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Sample records for publication nitrosamine contents

  1. Effect of modified atmosphere packaging and irradiation in combination on content of nitrosamines in cooked pork sausage.

    Science.gov (United States)

    Song, I H; Kim, W J; Jo, C; Ahn, H J; Kim, J H; Byun, M W

    2003-06-01

    The effect of modified atmosphere packaging and irradiation in combination on nitrosodimethylamine (NDMA) and nitrosopyrrolidine (NPYR) levels in pork sausage was studied. Emulsion-type cooked pork sausage was manufactured and packaged in aerobic, CO2 (100%), N2 (100%), and CO2/N2 (25%/75%) environments, respectively, and irradiated at 0, 5, 10, and 20 kGy with gamma irradiation. The nitrosamine contents were significantly reduced by irradiation, and the reduction of nitrosamines was more extensive with modified atmosphere packaging than with aerobic packaging. The correlation coefficient between irradiation dose and nitrosamine content indicated that irradiation can reduce the levels of nitrosamines. The combination of irradiation and modified atmosphere packaging is effective in enhancing the chemical safety of sausage by reducing nitrosamines, if present, as well as enhancing the microbial safety of cooked pork sausage.

  2. Evaluation of N-Nitrosamine Formation in Routine Potato Cooking

    Directory of Open Access Journals (Sweden)

    Qajarbeygi

    2015-08-01

    Full Text Available Background Nitrosamine is amongst carcinogen chemical compounds, which can enter the human body through consumption of food. Potatoes are a root vegetable consumed by many people around the world, however their potential for nitrosamine formation during cooking processes needs to be considered for public health matters. Objectives In this study we evaluated the effect of conventional potato cooking method on N-nitrosamine compound formation. Materials and Methods The amounts of four nitrosamines, namely N-nitrosodimethylamine (NDMA, N-nitrosodiethylamine (NDEA, N-nitrosopiperidine (NPIP and N-nitrosopyrrolidine (NPYR were determined in four different potato-baking methods. Sixty potato samples were randomly collected from Hamadan city. Fried potato samples were roasted at 180°C and boiled potato samples were scalded at 120°C. Nitrosamine levels were measured using gas chromatography coupled with electronic ionization detector (GC-EID, and spectrophotometry was used for measuring nitrite. Results Fried samples that were measured by the gas chromatography method had the highest average levels of nitrosamine compounds; NDMA, 5.09 ng kg-1, and NDEA, 8.66 ng kg-1. Low levels of nitrosamine compounds were associated with raw potatoes, in which no nitrosamine compound was detected. Based on the analysis of the potato samples by spectrophotometry, the highest levels of nitrite was found in raw potatoes with a mean of 2.43 mg kg-1 and the lowest levels of nitrite were detected in boiled potatoes with an average of 1.172 mg kg-1. Conclusions Nitrosamine was formed with conventional potato baking methods with the most nitrosamine formation found on the surface fried samples. Nitrites amount in baked potatoes decreased. Generally, the amount of nitrosamine in baked potato samples was lower than acceptable limits.

  3. N-Nitrosamines in the factory environment

    Energy Technology Data Exchange (ETDEWEB)

    Fajen, J M; Fine, D H; Rounbehler, D P

    1980-01-01

    Under the NIOSH-sponsored contract, a total of 40 surveys were conducted at 28 manufacturing plants. The industries investigated were the fish, dye, leather, rubber and manufacturers and users of cutting fluids. NDELA, NMOR, NDMA and NDPhA were found in the air of several factories. In a chrome tannery, NDMA was identified at levels as high as 47 micrograms/m3 and NMOR was found at 27 micrograms/m3 in a rubber tire plant. This study has resulted in an increased understanding of man's exposure to exogenous N-nitrosamines. It is conceivable, from the information obtained in this study, that nitrosamine exposure comparable to that in the tire and rubber industry exists in other industries not yet surveyed. NIOSH is continuing its research on nitrosamines in the industrial environment. A full, industry-wide report on the 40 plant surveys is being compiled for publication.

  4. A Review of Aspects of Oxidative Hair Dye Chemistry with Special Reference to N-Nitrosamine Formation

    Science.gov (United States)

    Lewis, David; Mama, John; Hawkes, Jamie

    2013-01-01

    This review discusses a new aspect to the safety profile of oxidative hair dyes using data already in the public domain. These dyes contain secondary amines that are capable of forming potentially carcinogenic nitrosamine derivatives when exposed to atmospheric pollution. Numerous scientific articles confirm the existence of secondary amines in hair dyes (and their intermediates), the possibility of nitrosation by atmospheric NOx of secondary amines to give the N-nitrosamines, and the significant safety risks on N-nitrosamines. It is believed that such nitrosamine derivatives should be investigated more fully in the interests of consumer safety. PMID:28809322

  5. A Review of Aspects of Oxidative Hair Dye Chemistry with Special Reference to N-Nitrosamine Formation

    Directory of Open Access Journals (Sweden)

    Jamie Hawkes

    2013-02-01

    Full Text Available This review discusses a new aspect to the safety profile of oxidative hair dyes using data already in the public domain. These dyes contain secondary amines that are capable of forming potentially carcinogenic nitrosamine derivatives when exposed to atmospheric pollution. Numerous scientific articles confirm the existence of secondary amines in hair dyes (and their intermediates, the possibility of nitrosation by atmospheric NOx of secondary amines to give the N-nitrosamines, and the significant safety risks on N-nitrosamines. It is believed that such nitrosamine derivatives should be investigated more fully in the interests of consumer safety.

  6. Detection and toxicity assessment of nitrosamines migration from latex gloves in the Chinese market.

    Science.gov (United States)

    Feng, Di; Wang, Huiping; Cheng, Xuelian; Wang, Jiedong; Ning, Lifeng; Zhou, Qingfeng; Zhou, Yue; Yang, Quanli

    2009-09-01

    Nitrosamines are potent carcinogens and have been found in latex products. In 2007, twenty-seven natural latex gloves including sterile gloves, examination gloves and household use gloves were sampled from the Chinese market. This study monitored the migration of nitrosamines and nitrosatable substance from these gloves, and evaluated their mutagenicity using a Salmonella typhimurium mutation assay (Ames assay) with the strains TA98, TA97, TA100 and TA102 and by a micronucleus test (MN test) using ICR mice. In addition, the cytotoxicity of these compounds was determined by a MTT assay. N-nitrosodimethylamine (NDMA), N-nitrosodiethylamine (NDEA) and N-nitrosodibutylamine (NDBA) were all found in samples treated with artificial sweat for 4h at 37 degrees C, and total nitrosamines varied from 18.89 to 244.51microg/Kg. The nitrosamine mixture of NDMA, NDEA and NDBA was used in both the Ames assay and the MN test. The proportion of NDMA, NDEA and NDBA (1:10:20) was selected according to the proportion of nitrosamines migration from sample E05. In the Ames assay, the lowest dose (1.98 x 10(-3)microg per plate) produced a positive result in the TA98 strain, corresponding to nitrosamines migration from sample E05 of 0.016g (the total nitrosamines migration from glove E05 was 122.55 microg/kg). The TA100 strain responded positively at a dose of 4.96 x 10(-2)microg per plate, corresponding to nitrosamines migration from glove E05 of 0.040g. The MN test showed nitrosamine migration of 3.04 mg from 2066 pairs of sample E05 and could induce micronuclei in one mouse weighing 28g (average weight of one E05 glove was 6g). Extracts from gloves were found to be cytotoxic and there was a significant correlation between cytotoxicity (IC50) and the release level of nitrosamines. In conclusion, in view of the high content of nitrosamines in latex gloves and the potential toxicity of nitrosamines migration from these gloves, it is suggested that both an effective and feasible detection

  7. Solid-Phase Extraction and High-Performance Liquid Chromatography Mass Spectrometry Analysis of Nitrosamines in Treated Drinking Water and Wastewater

    Science.gov (United States)

    N-Nitrosamines, including N-dimethylnitrosamine (NDMA), were identified as chlorination byproducts in drinking water in 1989. Nitrosamines are known rodent carcinogens and probable human carcinogens, so that they have been considered disinfection byproducts (DBPs) of public healt...

  8. [Nitrates and nitrites in meat products--nitrosamines precursors].

    Science.gov (United States)

    Avasilcăi, Liliana; Cuciureanu, Rodica

    2011-01-01

    To determine the content in nitrates and nitrites and the formation of two nitrosamines (N-nitrosodimethylamine--NDMA, and N-nitrosodiethylaamine--NDEA) in samples of chicken ham, dry Banat salami, dry French salami, traditional Romania sausages, and pork pastrami. Nitrites were determined by spectrophotometry with Peter-Griess reagent, and nitrates by the same method after reduction to nitrites with cadmium powder. High performance liquid chromatography with UV detection was used to determine nitrosamines. The initial concentration of nitrates, nitrites, NDMA and NDEA in the samples ranged as follows: 14.10-60.40 mg NO3/kg, 2.70-26.70 mg NO2/kg, from non-detectable to 0.90 microg NDMA/kg, and from non-detectable to 0.27 microg NDEA/kg, respectively. After 28 days the concentrations were: 3.24-17.1 mg NO3/kg, 0.04 -1.87 mg NO2/kg, 0.8-29 microg NDMA/kg, and 11.6-61.9 microg NDEA/kg, respectively. The decreased nitrate and nitrite and increased NDMA and NDEA concentrations prove that in food products nitrosamines are formed due to residual nitrite during their preservation. The determination of nitrasamines revealed levels much above the admitted maximal concentration for these food products.

  9. Determination of nitrate, nitrite, N- nitrosamines, cyanide and ...

    African Journals Online (AJOL)

    The nitrate, nitrite, N- nitrosamines and ascorbic acid content as well as the levels of cyanide in eight brands of fruit juices and twelve brands of sachet water commonly marketed and consumed in Nigeria were estimated. The mean values of nitrate ranged from 2.29±0.05 to 16.50±1.21 mg/L for the juices and 0.64±0.21 to ...

  10. Formation and mitigation of N-nitrosamines in nitrite preserved cooked sausages

    DEFF Research Database (Denmark)

    Herrmann, Susan Strange; Granby, Kit; Duedahl-Olesen, Lene

    2015-01-01

    Literature on formation and mitigation of N-nitrosamine (NA) and especially non-volatile NA (NVNA) in meat products is scarce and the present study is therefore a relevant contribution to the field. We found positive correlation between the levels of N-nitrosopiperidine (NPIP), N-nitrosohydroxypr...... and a combination of the two provided no further protection. Increasing the black pepper content increased the levels of NPIP and NMTCA. Only slight effects of increased fat content and addition of tripolyphosphate were observed....

  11. Occurrences of nitrosamines in chlorinated and chloraminated drinking water in three representative cities, China

    International Nuclear Information System (INIS)

    Luo, Qian; Wang, Donghong; Wang, Zijian

    2012-01-01

    An investigation of the occurrence of nine nitrosamines in drinking water following different water treatment processes was conducted using samples from seven drinking water treatment plants in three cities and tap waters in one city in China. The total nitrosamine levels ranged from not detected (n.d.) to 43.45 ng/L. The species and concentrations of the nine nitrosamines varied with disinfection methods and source waters. N-nitrosodimethylamine (NDMA), which is the nitrosamines of greatest concern, was identified in raw water, disinfecting water, finished water and tap water samples, ranging from 0.8 to 21.6, 0.12 to 24.2, n.d. to 8.8, and n.d. to 13.3 ng/L, respectively. Chloramination alone produced the most significant amounts of NDMA, while ozonation followed by chloramination led to moderately reduced levels. Additionally, chlorination produced relatively less NDMA, while low pressure ultraviolet radiation followed by chlorination could also significantly reduce them. Total organic carbon is one of the most important factors influencing nitrosamines formation in disinfecting water. In contrast, the addition of chlorine following any other disinfection was found to increase the formation of the other eight species of nitrosamines. The three nitrosamines recommended for monitoring by the US EPA were detected in the tap water samples, but most were present at levels below those that pose a risk to human health. Nevertheless, the occurrence and concentration of nitrosamines regulated in the Drinking Water Contaminant Candidate List could cause some potential human effects and therefore warrant attention. Highlights: ► Nitrosamines in disinfected drinking water in three Chinese cities were investigated. ► Some nitrosamines could be detected in raw water. ► Advanced treatment affects nitrosamine levels both positively and negatively. ► Organic matters contribute to increased nitrosamine level. ► Nitrosamine levels in this study were below the EPA MAC but

  12. Occurrences of nitrosamines in chlorinated and chloraminated drinking water in three representative cities, China

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Qian; Wang, Donghong; Wang, Zijian

    2012-10-15

    An investigation of the occurrence of nine nitrosamines in drinking water following different water treatment processes was conducted using samples from seven drinking water treatment plants in three cities and tap waters in one city in China. The total nitrosamine levels ranged from not detected (n.d.) to 43.45 ng/L. The species and concentrations of the nine nitrosamines varied with disinfection methods and source waters. N-nitrosodimethylamine (NDMA), which is the nitrosamines of greatest concern, was identified in raw water, disinfecting water, finished water and tap water samples, ranging from 0.8 to 21.6, 0.12 to 24.2, n.d. to 8.8, and n.d. to 13.3 ng/L, respectively. Chloramination alone produced the most significant amounts of NDMA, while ozonation followed by chloramination led to moderately reduced levels. Additionally, chlorination produced relatively less NDMA, while low pressure ultraviolet radiation followed by chlorination could also significantly reduce them. Total organic carbon is one of the most important factors influencing nitrosamines formation in disinfecting water. In contrast, the addition of chlorine following any other disinfection was found to increase the formation of the other eight species of nitrosamines. The three nitrosamines recommended for monitoring by the US EPA were detected in the tap water samples, but most were present at levels below those that pose a risk to human health. Nevertheless, the occurrence and concentration of nitrosamines regulated in the Drinking Water Contaminant Candidate List could cause some potential human effects and therefore warrant attention. Highlights: Black-Right-Pointing-Pointer Nitrosamines in disinfected drinking water in three Chinese cities were investigated. Black-Right-Pointing-Pointer Some nitrosamines could be detected in raw water. Black-Right-Pointing-Pointer Advanced treatment affects nitrosamine levels both positively and negatively. Black-Right-Pointing-Pointer Organic matters

  13. Zeolites for nitrosamine and pharmaceutical removal from demineralised and surface water: Mechanisms and efficacy

    KAUST Repository

    De Ridder, David J.

    2012-03-01

    Zeolites with a high Si/Al ratio can be used as selective adsorbents in water treatment, targeting organic micropollutants which are removed poorly with activated carbon. Due to size exclusion, many Natural Organic Matter (NOM) components cannot access the pores, thus limiting adsorption competition between organic micropollutant and NOM. Furthermore, zeolite channel diameters are close to molecule diameters, which results in strong van der Waals interaction. MOR200 and ZSM5, the two most hydrophobic zeolites, showed the highest removal of neutral nitrosamines in demineralised water, with higher efficacy than activated carbon. DAY and MOR30, which were relatively hydrophilic zeolites, did not show appreciable removal of any of the nitrosamines. When nitrosamines were adsorbed from surface water, there was no influence of competition with, or pore blockage by, NOM components on nitrosamine removal for ZSM5 zeolite, in contrast to activated carbon. Repulsion of negatively charged pharmaceuticals was significant for ZSM5, which had a Si/Al ratio of 80. MOR200 had a Si/Al ratio of 200, indicating a lower Al content than ZSM5 and, as such, a lower negative surface charge. Charge effects were not observed for MOR200. A relationship was found between the Stokes diameter of the pharmaceuticals and nitrosamines, and their removal by ZSM5 and MOR200, indicating that a "close fit" adsorption mechanism is more likely than hydrophobic interaction in these zeolites. Due to their selective nature, adsorption on zeolites should only be considered as an additional treatment step to existing processes, dedicated for the removal of specific organic micropollutants. Less specific treatment techniques, such as activated carbon filtration, are still required to ensure a broad barrier for organic micropollutants in water treatment. © 2012 Elsevier B.V. All rights reserved.

  14. Simplified method for the determination of N-nitrosamines in rubber vulcanizates

    Energy Technology Data Exchange (ETDEWEB)

    Incavo, Joseph A [Goodyear Tire and Rubber Company, Akron, OH (United States); Schafer, Melvin A [oodyear Tire and Rubber Company, Akron, OH (United States)

    2006-01-31

    A simplified method for the trace determination of N-nitrosamines in carbon black-loaded rubber compounds is described. The extraction of volatile nitrosamines is accomplished by thermal desorption rather than the traditional solvent extraction procedure. The analytes are trapped on Thermosorb/N sorbent and subsequently analyzed by gas chromatography with thermal energy analyzer detection (GC/TEA). Conditions that provide full extraction of nitrosamines from actual rubber compounds were determined to be 30 min at 150 deg. C in vessels dynamically purged with N{sub 2}. Method precision was found to be 10% for NDMA at 71 ng/g and 7.3% for NMOR at 248 ng/g. Recoveries for the seven common N-nitrosamines ranged from 94 to 117%. Limits of detection in the rubber matrix are 6.3-13 ng/g. The technique is found to offer improved recovery of lower molecular weight nitrosamines and it is shown to be simpler and faster than previous techniques.

  15. Simplified method for the determination of N-nitrosamines in rubber vulcanizates

    International Nuclear Information System (INIS)

    Incavo, Joseph A.; Schafer, Melvin A.

    2006-01-01

    A simplified method for the trace determination of N-nitrosamines in carbon black-loaded rubber compounds is described. The extraction of volatile nitrosamines is accomplished by thermal desorption rather than the traditional solvent extraction procedure. The analytes are trapped on Thermosorb/N sorbent and subsequently analyzed by gas chromatography with thermal energy analyzer detection (GC/TEA). Conditions that provide full extraction of nitrosamines from actual rubber compounds were determined to be 30 min at 150 deg. C in vessels dynamically purged with N 2 . Method precision was found to be 10% for NDMA at 71 ng/g and 7.3% for NMOR at 248 ng/g. Recoveries for the seven common N-nitrosamines ranged from 94 to 117%. Limits of detection in the rubber matrix are 6.3-13 ng/g. The technique is found to offer improved recovery of lower molecular weight nitrosamines and it is shown to be simpler and faster than previous techniques

  16. Monitoring exposure of personnel to volatile nitrosamines in the laboratory environment

    Energy Technology Data Exchange (ETDEWEB)

    Issenberg, P; Swanson, S E

    1980-01-01

    A convenient sampling method was developed for collection of volatile nitrosamines from large-volume air samples. Stainless steel tubes containing 0.3 g Tenax GC were employed to collect nitrosamines from 5-30 1 air samples. Nitrosamines were eluted from the sample tubes with diethylether to minimize formation of artifacts which were observed when thermal desorption was employed. Eluates were analysed directly by GC-TEA and nitrosamine identities were confirmed using high-resolution GC-MS with selected ion-monitoring. The detection limit was approximately 0.8 micrograms/m3 (0.3 ppb) for NDMA in 2 ml of diethylether extract. The laboratory operations studied included chemical synthesis, trace analysis, animal treatment, microbial mutagenesis tests and in vitro biochemical procedures. In most cases, nitrosamines were not detected in laboratory air, but levels of 200-800 micrograms/m3 (42 to 180 ppb) of N-nitrosomethyl-tert-butylamine were measured during animal treatment, 0.8-8.6 micrograms/m3 (0.3 to 2.8 ppb) of NDMA during mutagenesis assays, 12-22 micrograms/m3 (4-7 ppb) of NDMA during in vitro metabolism studies and 11 micrograms/m3 (3.6 ppb) of NDMA in a walk-in refrigerator. Appropriate corrective measures reduced all nitrosamine levels to below the detection limit. Hamsters and rats treated with NDAA (80 mg/kg, s.c.) excreted 4.4 and 12.9%, respectively, of the nitrosamine in expired air in 24 hr. This route of excretion may be metabolically significant and should be considered in the safe design of animal treatment and holding facilities.

  17. Formation of Nitrosamines in Food and in the Digestive System

    Science.gov (United States)

    Wishnok, John S.

    1977-01-01

    A discussion is presented of the toxicity, chemistry, and environmental presence of nitrosamines. Carcinogenicity and effects on various organs of test animals are reviewed. Also some information on the presence of use of nitrosamines in human food is given. (MR)

  18. N-nitrosamines in drinking water and beer: Detection and risk assessment.

    Science.gov (United States)

    Fan, Chun-Cheng; Lin, Tsair-Fuh

    2018-06-01

    Occurrence and risk related to nitrosamines, a group of carcinogenic compounds found in some drinking waters and beer, are studied. An analytical method using a solid-phase micro-extraction (SPME) along with gas chromatography (GC) and mass spectrometry (MS) was developed to determine seven N-nitrosamines in drinking water and beer, including N-nitrosomethylamine (NMEA), N-nitrosodiethylamine (NDEA), N-nitrosodimethylamine (NDMA), N-nitrosodi-n-propylamine (NDPA), N-nitrosopyrrolidine (NPyr), N-nitrosopiperidine (NPip), and N-nitrosodinbutylamine (NDBA). The analysis can be completed in 70 min, and only a 4 mL sample is required, with a detection limit of 0.1-0.8 ng/L for the seven nitrosamines in water and 6-15.7 ng/L in beer. The method was applied to analyze water samples collected from 11 reservoirs and their associated drinking water treatment plants in Taiwan and 10 beer samples from 6 brands with factories located in 6 countries. In the drinking water samples, all seven N-nitrosamines were detected, with NDMA having the highest level at 10.2 ng/L. In the beer samples, NDMA was detected at much lower concentrations (0.12-0.23 μg/L) than the 5 μg/L US standard, while NPip was detected at much higher concentrations (4.1-5.3 μg/L) compared to NDMA. The risk assessment indicates that the risk associated with NDMA is the highest among the studied N-nitrosamines in Taiwan's drinking water, with an average cancer risk of 6.4 × 10 -06 . For other nitrosamines, the risks are all below 10 -6 . For the risks associated with N-nitrosamines in beer, NDMA, NDEA, NDPA, and NPip are in the range of 1.5 × 10 -05 to 4.6 × 10 -04 , while that for other nitrosamines are much lower. As for beer, no information for NPip and no modern information for NDEA and NDPA have previously been available, more studies about nitrosamines in beer are suggested for better estimation and control of the risks associated with consumption of beer. Copyright © 2018

  19. Novel Study on N-Nitrosamines as Risk Factors of Cardiovascular Diseases

    Directory of Open Access Journals (Sweden)

    Salah A. Sheweita

    2014-01-01

    Full Text Available Millions of people are exposed daily to N-nitrosamines from different environmental sources. The present study aims at investigating the role of N-nitrosamines in the alteration of homocysteine, lipid profile, oxidative stress, paraoxonase activity, antioxidant enzymes, and free radicals which are important risk factors for CVD. In addition, biomarkers of cardiovascular diseases such as creatine kinase MB activity (CK-MB and lactate dehydrogenase (LDH as well as protein expression of both glutathione peroxidase and glutathione S-transferase π isozyme were assayed after treatment of rats with 0.2 mg/kg body weight of N-nitrosodibutylamine (NDBA, N-nitrosoethylbutylamine (NEBA, N-nitrosobutylpropylamine (NBPA, N-nitrosodiethylamine (NDEA, N-nitrosodimethylamine (NDMA, and N-nitrosodiphenylamine (NDPA as a daily dose for two weeks. LDL levels, paraoxonase activity, reduced glutathione levels, and glutathione reductase activities were increased, whereas HDL levels decreased after treatment of rats with most of N-nitrosamines compared to control group. Moreover, levels of free radicals and catalase activity increased, whereas protein expression of both glutathione peroxidase and glutathione S-transferase decreased after treatment of rats with some N-nitrosamines. The data showed that most N-nitrosamines increased CK-MB and LDH activities. It is concluded that N-nitrosamines increased levels of free radicals, and decreased the activity of antioxidant enzymes which may consequently increase the incidence of CVDs.

  20. Ingestion Exposure to Nitrosamines in Chlorinated Drinking Water

    Science.gov (United States)

    Han, Kichan

    2011-01-01

    Objectives N-Nitrosodimethylamine (NDMA) is classified as a probable human carcinogen by the United States Environmental Protection Agency (US EPA) and is formed during the chlorination of municipal drinking water. In this study, selected nitrosamines were measured in chlorinated drinking water collected from Chuncheon, Kangwon-do, Republic of Korea, and a risk assessment for NDMA was conducted. Methods Twelve water samples were collected from 2 treatment plants and 10 household taps. Samples were analyzed for 6 nitrosamines via solid-phase extraction cleanup followed by conversion to dansyl derivatives and high-performance liquid chromatography-fluorescence detection (HPLC-FLD). Considering the dietary patterns of Korean people and the concentration change of NDMA by boiling, a carcinogenic risk assessment from ingestion exposure was conducted following the US EPA guidelines. Results NDMA concentrations ranged between 26.1 and 112.0 ng/L. NDMA in water was found to be thermally stable, and thus its concentration at the end of boiling was greater than before thermal treatment owing to the decrease in water volume. The estimated excess lifetime carcinogenic risk exceeded the regulatory baseline risk of 10-5. Conclusions This result suggests that more extensive studies need to be conducted on nitrosamine concentration distributions over the country and the source of relatively high nitrosamine concentrations. PMID:22125764

  1. Formation, precursors, control, and occurrence of nitrosamines in drinking water: a review.

    Science.gov (United States)

    Krasner, Stuart W; Mitch, William A; McCurry, Daniel L; Hanigan, David; Westerhoff, Paul

    2013-09-01

    This review summarizes major findings over the last decade related to nitrosamines in drinking water, with a particular focus on N-nitrosodimethylamine (NDMA), because it is among the most widely detected nitrosamines in drinking waters. The reaction of inorganic dichloramine with amine precursors is likely the dominant mechanism responsible for NDMA formation in drinking waters. Even when occurrence surveys found NDMA formation in chlorinated drinking waters, it is unclear whether chloramination resulted from ammonia in the source waters. NDMA formation has been associated with the use of quaternary amine-based coagulants and anion exchange resins, and wastewater-impaired source waters. Specific NDMA precursors in wastewater-impacted source waters may include tertiary amine-containing pharmaceuticals or other quaternary amine-containing constituents of personal care products. Options for nitrosamine control include physical removal of precursors by activated carbon or precursor deactivation by application of oxidants, particularly ozone or chlorine, upstream of chloramination. Although NDMA has been the most prevalent nitrosamine detected in worldwide occurrence surveys, it may account for only ≈ 5% of all nitrosamines in chloraminated drinking waters. Other significant contributors to total nitrosamines are poorly characterized. However, high levels of certain low molecular weight nitrosamines have been detected in certain Chinese waters suspected to be impaired by industrial effluents. The review concludes by identifying research needs that should be addressed over the next decade. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. [Formation of nitrosamines in cheese products].

    Science.gov (United States)

    Klein, D; Keshavarz, A; Lafont, P; Hardy, J; Debry, G

    1980-01-01

    Several strains of micromycetes used as fermentation agents in the cheese industry or having led to accidents during cheese making are able to favor the formation of nitrosamines in 60% of the cases. The concentrations observed are similar to those found by other authors with other microorganisms. The results obtained in a semi-synthetic medium are checked during the ripening of experimental camembert type cheese made from milk containing nitrates and cultured with a strain of Penicillium camemberti, which favors very much the synthesis of nitrosamines. The amount of nitrosodimethylamine formed in this cheese increases from 5 to 20 ppb during ripening. A tentative explanation of the mechanism of formation is outlined.

  3. Metabolism of acyclic and cyclic N-nitrosamines in cultured human bronchi

    DEFF Research Database (Denmark)

    Harris, Curtis C.; Autrup, Herman; Stoner, Gary D.

    1977-01-01

    The metabolism of carcinogenic N-nitrosamines was studied in normal-appearing bronchial specimens obtained from 4 patients. Explants of bronchi were cultured in a chemically defined medium for 7 days. N-Nitrosamines [N-nitrosodimethylamine (DMN), N-nitrosodiethylamine (DEN), N,N'-dinitrosopiperaz...

  4. Specific and total N-nitrosamines formation potentials of nitrogenous micropollutants during chloramination.

    Science.gov (United States)

    Piazzoli, Andrea; Breider, Florian; Aquillon, Caroline Gachet; Antonelli, Manuela; von Gunten, Urs

    2018-05-15

    N-nitrosamines are a group of potent human carcinogens that can be formed during oxidative treatment of drinking water and wastewater. Many tertiary and quaternary amines present in consumer products (e.g., pharmaceuticals, personal care and household products) are known to be N-nitrosodimethylamine (NDMA) precursors during chloramination, but the formation of other N-nitrosamines has been rarely studied. This study investigates the specific and total N-nitrosamine (TONO) formation potential (FP) of various precursors from nitrogen-containing micropollutants (chlorhexidine, metformin, benzalkonium chloride and cetyltrimethylammonium chloride) and tertiary and quaternary model amines (trimethyl amine, N,N-dimethylbutyl amine, N,N-dimethylbenzyl amine and tetramethyl ammonium). All the studied nitrogenous micropollutants displayed quantifiable TONO FP, with molar yields in the range 0.04-11.92%. However, the observed TONO pools constituted mostly of uncharacterized species, not included in US-EPA 8270 N-nitrosamines standard mix. Only the quaternary ammonium compound benzalkonium chloride showed quantifiable NDMA FP (0.56% molar yield), however, explaining only a minor fraction of the observed TONO FP. The studied model amines showed molar NDMA yields from 0.10% (trimethyl amine) to 5.05% (N,N-dimethylbenzyl amine), very similar to the molar TONO yields. The comparison of the FPs of micropollutants and model compounds showed that the presence of electron donating functional groups (such as a benzyl group) in tertiary and quaternary amine precursors leads to a higher formation of NDMA and uncharacterized N-nitrosamines, respectively. LC-qTOF screening of a list of proposed N-nitrosamine structures has enabled to identify a novel N-nitrosamine (N-nitroso-N-methyldodecylamine) from the chloramination of benzalkonium chloride. This finding supports the hypothesis that different functional groups in quaternary amines can act as leaving groups during chloramination and

  5. Occurrences of nitrosamines in chlorinated and chloraminated drinking water in three representative cities, China.

    Science.gov (United States)

    Luo, Qian; Wang, Donghong; Wang, Zijian

    2012-10-15

    An investigation of the occurrence of nine nitrosamines in drinking water following different water treatment processes was conducted using samples from seven drinking water treatment plants in three cities and tap waters in one city in China. The total nitrosamine levels ranged from not detected (n.d.) to 43.45 ng/L. The species and concentrations of the nine nitrosamines varied with disinfection methods and source waters. N-nitrosodimethylamine (NDMA), which is the nitrosamines of greatest concern, was identified in raw water, disinfecting water, finished water and tap water samples, ranging from 0.8 to 21.6, 0.12 to 24.2, n.d. to 8.8, and n.d. to 13.3 ng/L, respectively. Chloramination alone produced the most significant amounts of NDMA, while ozonation followed by chloramination led to moderately reduced levels. Additionally, chlorination produced relatively less NDMA, while low pressure ultraviolet radiation followed by chlorination could also significantly reduce them. Total organic carbon is one of the most important factors influencing nitrosamines formation in disinfecting water. In contrast, the addition of chlorine following any other disinfection was found to increase the formation of the other eight species of nitrosamines. The three nitrosamines recommended for monitoring by the US EPA were detected in the tap water samples, but most were present at levels below those that pose a risk to human health. Nevertheless, the occurrence and concentration of nitrosamines regulated in the Drinking Water Contaminant Candidate List could cause some potential human effects and therefore warrant attention. Copyright © 2012 Elsevier B.V. All rights reserved.

  6. Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the Short Willet Food Frequency Questionnaire.

    Science.gov (United States)

    Griesenbeck, John S; Steck, Michelle D; Huber, John C; Sharkey, Joseph R; Rene, Antonio A; Brender, Jean D

    2009-04-06

    Studies have suggested that nitrates, nitrites, and nitrosamines have an etiologic role in adverse pregnancy outcomes and chronic diseases such as cancer. Although an extensive body of literature exists on estimates of these compounds in foods, the extant data varies in quality, quantified estimates, and relevance. We developed estimates of nitrates, nitrites, and nitrosamines for food items listed in the Short Willet Food Frequency Questionnaire (WFFQ) as adapted for use in the National Birth Defects Prevention Study. Multiple reference databases were searched for published literature reflecting nitrate, nitrite, and nitrosamine values in foods. Relevant published literature was reviewed; only publications reporting results for items listed on the WFFQ were selected for inclusion. The references selected were prioritized according to relevance to the U.S. population. Based on our estimates, vegetable products contain the highest levels of nitrate, contributing as much as 189 mg/serving. Meat and bean products contain the highest levels of nitrites with values up to 1.84 mg/serving. Alcohol, meat and dairy products contain the highest values of nitrosamines with a maximum value of 0.531 microg/serving. The estimates of dietary nitrates, nitrites, and nitrosamines generated in this study are based on the published values currently available. To our knowledge, these are the only estimates specifically designed for use with the adapted WFFQ and generated to represent food items available to the U.S. population. The estimates provided may be useful in other research studies, specifically in those exploring the relation between exposure to these compounds in foods and adverse health outcomes.

  7. N-nitrosamines induced infertility and hepatotoxicity in male rabbits.

    Science.gov (United States)

    Sheweita, S A; El Banna, Y Y; Balbaa, M; Abdullah, I A; Hassan, H E

    2017-09-01

    N-nitrosamines are widely spread environmental pollutants of well-known toxicity and carcinogenicity in various animal species. These compounds are metabolically activated by cytochrome P450 system predominantly in the liver and in other tissues into more active metabolites leading to generation of both alkylating agents that alkylate DNA and reactive oxygen species. In the current study, we investigated the influence of four types of N-nitrosamines that are commonly present in the environment [methyethylnitrosamine, (MEN), diethylnitrosamine (DEN), diphenylnitroasamine (DPN) and dimethylnitrosamine (DMN)] on both livers and testes of male rabbits through assessment of 17 β-hydroxysteroid dehydrogenase (17 β-HSD) activity. The protein expression of the three cytochrome P450s (CYP11A1, CYP19A1, and CYP21A2) is involved in the steroidogenesis. The levels of testosterone (T) and estradiol (E2) were also determined in the plasma of N-nitrosamines-treated rabbits after one, four-, eight- and twelve weeks of treatment of male New Zealand rabbits with an oral dose of 0.5 mg/kg B.W/day of each compound. In addition, activities of glutathione reductase (GR), superoxide dismutase (SOD), catalase (CAT) and levels of free radicals measured as thiobarbituric acid reactive substances (TBARS), and reduced glutathione (GSH) level were quantified in both livers and testes. The present study showed that levels of free radicals (TBARS) were markedly increased, whereas GSH levels were depleted in the tissues of both livers and testes after treatment of rabbits with any of N-nitrosamines. In addition, all tested N-nitrosamines inhibited the activities of antioxidant enzyme activities (GR, GST, SOD, and CAT) in hepatic and testicular tissues of rabbits after 12 weeks of treatment. Histopathological examination showed that N-nitrosamines caused lymphocytic infiltration with vascular degeneration and necrosis, congestion of central vein with RBCs hemolysis, dilated sinusoids, as well as

  8. Carcinogenic nitrosamines in traditional beer as the cause of oesophageal squamous cell carcinoma in black South Africans.

    Science.gov (United States)

    Pillay, Viness; Isaacson, Charles; Mothobi, Pride; Hale, Martin; Tomar, Lomas Kumar; Tyagi, Charu; Altini, Mario; Choonara, Yahya Essop; Kumar, Pradeep

    2015-09-21

    Before the 1930s, squamous cell carcinoma (SCC) of the oesophagus was almost unknown among black South Africans. From the 1930s the annual frequency rose. A dietary cause was sought, the staple diet of black people having changed from sorghum to maize (corn), with traditional beer being brewed from maize. Carcinogenic N-nitrosamines in traditional beer were suggested as a cause of SCC of the oesophagus, with Fusarium moniliforme, a corn saprophyte, thought to play a role. To confirm the presence of N-nitrosamines in traditional beer and demonstrate a mechanism for the oncogenesis of oesophageal carcinoma. Analysis by high-performance liquid chromatography was conducted for the identification of nitrosamines in traditional beer samples, and molecular docking studies were employed to predict the affinity between N-nitrosamines and the S100A2 protein. Carcinogenic N-nitrosamines were identified in all six samples of traditional beer examined (N=18 analyses), and docking studies confirmed a high affinity of the nitrosamine N-nitrosopyrrolidone with the S100A2 protein. This may result in the altered expression of the S100A2 protein, leading to tumour progression and prognosis. It is suggested that carcinogenic N-nitrosamines in traditional beer are a major factor in the causation of SCC of the oesophagus in black South Africans. N-nitrosamines have been shown to produce cancer experimentally, but there has not been conclusive epidemiological evidence that N-nitrosamines are carcinogenic to humans. This study is the first to demonstrate the potential link between N-nitrosamines and a human tumour.

  9. Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the short willet food frequency questionnaire

    Directory of Open Access Journals (Sweden)

    Rene Antonio A

    2009-04-01

    Full Text Available Abstract Background Studies have suggested that nitrates, nitrites, and nitrosamines have an etiologic role in adverse pregnancy outcomes and chronic diseases such as cancer. Although an extensive body of literature exists on estimates of these compounds in foods, the extant data varies in quality, quantified estimates, and relevance. Methods We developed estimates of nitrates, nitrites, and nitrosamines for food items listed in the Short Willet Food Frequency Questionnaire (WFFQ as adapted for use in the National Birth Defects Prevention Study. Multiple reference databases were searched for published literature reflecting nitrate, nitrite, and nitrosamine values in foods. Relevant published literature was reviewed; only publications reporting results for items listed on the WFFQ were selected for inclusion. The references selected were prioritized according to relevance to the U.S. population. Results Based on our estimates, vegetable products contain the highest levels of nitrate, contributing as much as 189 mg/serving. Meat and bean products contain the highest levels of nitrites with values up to 1.84 mg/serving. Alcohol, meat and dairy products contain the highest values of nitrosamines with a maximum value of 0.531 μg/serving. The estimates of dietary nitrates, nitrites, and nitrosamines generated in this study are based on the published values currently available. Conclusion To our knowledge, these are the only estimates specifically designed for use with the adapted WFFQ and generated to represent food items available to the U.S. population. The estimates provided may be useful in other research studies, specifically in those exploring the relation between exposure to these compounds in foods and adverse health outcomes.

  10. Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the short willet food frequency questionnaire

    Science.gov (United States)

    Griesenbeck, John S; Steck, Michelle D; Huber, John C; Sharkey, Joseph R; Rene, Antonio A; Brender, Jean D

    2009-01-01

    Background Studies have suggested that nitrates, nitrites, and nitrosamines have an etiologic role in adverse pregnancy outcomes and chronic diseases such as cancer. Although an extensive body of literature exists on estimates of these compounds in foods, the extant data varies in quality, quantified estimates, and relevance. Methods We developed estimates of nitrates, nitrites, and nitrosamines for food items listed in the Short Willet Food Frequency Questionnaire (WFFQ) as adapted for use in the National Birth Defects Prevention Study. Multiple reference databases were searched for published literature reflecting nitrate, nitrite, and nitrosamine values in foods. Relevant published literature was reviewed; only publications reporting results for items listed on the WFFQ were selected for inclusion. The references selected were prioritized according to relevance to the U.S. population. Results Based on our estimates, vegetable products contain the highest levels of nitrate, contributing as much as 189 mg/serving. Meat and bean products contain the highest levels of nitrites with values up to 1.84 mg/serving. Alcohol, meat and dairy products contain the highest values of nitrosamines with a maximum value of 0.531 μg/serving. The estimates of dietary nitrates, nitrites, and nitrosamines generated in this study are based on the published values currently available. Conclusion To our knowledge, these are the only estimates specifically designed for use with the adapted WFFQ and generated to represent food items available to the U.S. population. The estimates provided may be useful in other research studies, specifically in those exploring the relation between exposure to these compounds in foods and adverse health outcomes. PMID:19348679

  11. Spatial and temporal occurrence of N-nitrosamines in seven drinking water supply systems.

    Science.gov (United States)

    Brisson, Isabelle J; Levallois, Patrick; Tremblay, Hélène; Sérodes, Jean; Deblois, Christian; Charrois, Jeffrey; Taguchi, Vincent; Boyd, Jessica; Li, Xingfang; Rodriguez, Manuel J

    2013-09-01

    The spatiotemporal presence of eight N-nitrosamines in the water of seven supply systems in Quebec considered to be susceptible to these emerging disinfection by-products was evaluated. This is the first study on the presence of N-nitrosamines in drinking water utilities in Quebec. Seven sampling campaigns were carried out at several sampling points in each of the systems over a period of 1 year. The results show that N-nitrosamines, primarily N-nitrosodimethylamine (NDMA), were not commonly detected in the water of the facilities under study (10 % of samples). The concentrations measured were lower than those reported in recent North American studies. None of the 195 samples taken exceeded the Ontario standard of 9 ng/L for NDMA (maximum value observed of 3.3 ng/L). N-nitrosomethylethylamine and N-nitrosopiperidine were detected once, with concentrations of 3.7 and 6.0 ng/L, respectively. Chloramination was identified as being the main risk factor regarding the presence of N-nitrosamines, but water quality and some operating parameters, in particular disinfectant residual, also seem to be related to their presence. NDMA concentrations at the end of the distribution systems were generally higher than water leaving the plant. No seasonal trends were observed for the formation of N-nitrosamines in the investigated supply systems. Finally, an association between the presence of N-nitrosamines and the levels of trihalomethanes and haloacetic acids was observed in some facilities.

  12. N-nitrosamine formation by monochloramine, free chlorine, and peracetic acid disinfection with presence of amine precursors in drinking water system.

    Science.gov (United States)

    West, Danielle M; Wu, Qihua; Donovan, Ariel; Shi, Honglan; Ma, Yinfa; Jiang, Hua; Wang, Jianmin

    2016-06-01

    In this study, the formation of eight N-nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosodiethylamine, N-nitrosomethylamine, N-nitrosodi-n-propylamine, N-nitrosodi-n-butylamine, N-Nitrosopiperidine, N-Nitrosopyrrolidine, N-Nitrosomorpholine, were systematically evaluated with respect to seven N-nitrosamine precursors (dimethylamine, trimethylamine, 3-(dimethylaminomethyl)indole, 4-dimethylaminoantipyrine, ethylmethylamine, diethylamine, dipropylamine) and three disinfectants (monochloramine, free chlorine, peracetic acid) under variable dosages, exposure times, and pH in a drinking water system. Without the presence of the seven selected N-nitrosamine precursors N-nitrosamine formation was not observed under any tested condition except very low levels of N-Nitrosopyrrolidine under some conditions. With selected N-nitrosamine precursors present N-nitrosamines formed at different levels under different conditions. The highest N-nitrosamine formation was NDMA with a maximum concentration of 1180 ng/L by monochloramine disinfection with precursors present; much lower levels of N-nitrosamines were formed by free chlorine disinfection; and no detectable level of N-nitrosamines were observed by peracetic acid disinfection except low level of N-Nitrosodi-n-propylamine under some conditions. NDMA formation was not affected by pH while four other N-nitrosamine formations were slightly affected by sample pH tested between 7 and 9, with formation decreasing with increasing pH. Monochloramine exposure time study displayed fast formation of N-nitrosamines, largely formed in four hours of exposure and maximized after seven days. This was a systematic study on the N-nitrosamine formation with the seven major N-nitrosamine precursors presence and absence under different conditions, including peracetic acid disinfection which has not been studied elsewhere. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA

    Directory of Open Access Journals (Sweden)

    Eleno Rodrigues Vieira

    2006-01-01

    Full Text Available N-Nitrosamines are receiving special attention because they present high mutagenic and carcinogenic potential. They can be found in several areas. In rubber, for example, they can be found in Nipples and Pacifiers. Spiegelhalder and Pressumann, have observed that N-Nitrosamines present in nipples and pacifiers could easily migrate to artificial saliva. They have also observed that a considerable amount of N-Nitrosamines precursors, such as nitrosable amines, could migrate to saliva, increasing the possibility of N-Nitrosamines formation into the stomach of living beings. In 80's, Holland, Germany and FDA-U.S.A. have established volatile N-Nitrosamines limit levels. In 2002, in Brazil, limit levels came through Resolução RDC n° 221 of ANVISA. This resolution refers to NBR10334 and NBR 13793 standards where limits and analysis methods are specified. In this work SENAICETEPO presents the method adopted for determination of N-Nitrosamines and N-Nitrosables in nipples and pacifiers. The detection and determination limits of the analytical system as well the method uncertainty were evaluated, in order to demonstrate the adequacy of this technique to comply with the requirements of NBR10334/2003 and NBR 13793/2003 standard.

  14. Volatile N-nitrosamines in meat products: Potential precursors, influence of processing, and mitigation strategies.

    Science.gov (United States)

    De Mey, Eveline; De Maere, Hannelore; Paelinck, Hubert; Fraeye, Ilse

    2017-09-02

    Meat products can be contaminated with carcinogenic N-nitrosamines, which is ascribed to the reaction between a nitrosating agent, originating from nitrite or smoke, and a secondary amine, derived from protein and lipid degradation. Although in model systems it is demonstrated that many amine containing compounds can be converted to N-nitrosamines, the yield is dependent of reaction conditions (e.g., low pH and high temperature). In this article, the influence of the composition of the meat products (e.g., pH, a w , spices) and processing (e.g., ageing, ripening, fermentation, smoking, heat treatment and storage) on the presence and availability of the amine precursors and the N-nitrosamine formation mechanism is discussed. In addition, this article explores the current N-nitrosamine mitigation strategies in order to obtain healthier and more natural meat products.

  15. Controlling Nitrosamines, Nitramines, and Amines in Amine-Based CO₂ Capture Systems with Continuous Ultraviolet and Ozone Treatment of Washwater.

    Science.gov (United States)

    Dai, Ning; Mitch, William A

    2015-07-21

    Formation of nitrosamines and nitramines from reactions between flue gas NOx and the amines used in CO2 capture units has arisen as a significant concern. Washwater scrubbers can capture nitrosamines and nitramines. They can also capture amines, preventing formation of nitrosamines and nitramines downwind by amine reactions with ambient NOx. The continuous application of UV alone, or a combination of UV and ozone to the return line of a washwater treatment unit was evaluated to control the accumulation of nitrosamines, nitramines and amines in a laboratory-scale washwater unit. With model secondary amine solvents ranging from nonvolatile diethanolamine to volatile morpholine, application of 272-537 mJ/cm(2) UV incident fluence alone reduced the accumulation of nitrosamines and nitramines by approximately an order of magnitude. Modeling indicated that the gains achieved by UV treatment should increase over time, because UV treatment converts the time dependence of nitrosamine accumulation from a quadratic to a linear function. Ozone (21 mg/L) maintained low steady-state concentrations of amines in the washwater. While modeling indicated that more than 80% of nitrosamine accumulation in the washwater was associated with reaction of washwater amines with residual NOx, a reduction in nitrosamine accumulation rates due to ozone oxidation of amines was not fully realized because the ozonation products of amines reduced nitrosamine photolysis rates by competing for photons.

  16. GC determination of N-nitrosamines by supersonic molecular beam MS equipped with triple quadrupole analyzer, GC/SMB/QQQ/MS

    International Nuclear Information System (INIS)

    Anna, Voloshenko; Rimma, Shelkov; Lev, Ovadia; Jenny, Gun

    2011-01-01

    The determination of 14 N-nitrosamines by a supersonic molecular beam electron ionization mass spectrometer equipped with triple quadruple analyzer, GC/SMB/EI/QQQ/MS is presented. The supersonic molecular beam electron ionization ion source allows the elucidation of the molecular ion of 13 out of the 14 examined nitrosamines (except for diphenylnitrosamine which was degraded before the analysis). It was possible to use the molecular ions of all the nitrosamines as the parent ions for multiple reactions monitoring mode, which in turn allows significant increase of specificity and lowering of the method limit of detection of the higher molecular weight nitrosamines. The instrumental LOD for different N-nitrosamines was 1-5 pg injection -1 . The proposed method was exemplified by analysis of N-nitrosamines and N-nitrosatables in rubber teats according to the British Standard BS EN 12868:1999.

  17. Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment

    Directory of Open Access Journals (Sweden)

    de la Monte Suzanne M

    2009-12-01

    Full Text Available Abstract Background The current epidemics of type 2 diabetes mellitus (T2DM, non-alcoholic steatohepatitis (NASH, and Alzheimer's disease (AD all represent insulin-resistance diseases. Previous studies linked insulin resistance diseases to high fat diets or exposure to streptozotocin, a nitrosamine-related compound that causes T2DM, NASH, and AD-type neurodegeneration. We hypothesize that low-level exposure to nitrosamines that are widely present in processed foods, amplifies the deleterious effects of high fat intake in promoting T2DM, NASH, and neurodegeneration. Methods Long Evans rat pups were treated with N-nitrosodiethylamine (NDEA by i.p. Injection, and upon weaning, they were fed with high fat (60%; HFD or low fat (5%; LFD chow for 6 weeks. Rats were evaluated for cognitive impairment, insulin resistance, and neurodegeneration using behavioral, biochemical, molecular, and histological methods. Results NDEA and HFD ± NDEA caused T2DM, NASH, deficits in spatial learning, and neurodegeneration with hepatic and brain insulin and/or IGF resistance, and reductions in tau and choline acetyltransferase levels in the temporal lobe. In addition, pro-ceramide genes, which promote insulin resistance, were increased in livers and brains of rats exposed to NDEA, HFD, or both. In nearly all assays, the adverse effects of HFD+NDEA were worse than either treatment alone. Conclusions Environmental and food contaminant exposures to low, sub-mutagenic levels of nitrosamines, together with chronic HFD feeding, function synergistically to promote major insulin resistance diseases including T2DM, NASH, and AD-type neurodegeneration. Steps to minimize human exposure to nitrosamines and consumption of high-fat content foods are needed to quell these costly and devastating epidemics.

  18. Nitrosamine degradation by UV light in post-combustion CO2 capture: effect of solvent matrix

    NARCIS (Netherlands)

    Miguel Mercader, F. de; Voice, A.K.; Trap, H.C.; Goetheer, E.L.V.

    2013-01-01

    Potential production and emission of nitrosamines during post-combustion CO2 capture has drawn some attention due to their toxicity and potential carcinogenicity. One of the possible ways to reduce the concentration of nitrosamines is irradiation of the liquid streams of the capture plant with UV

  19. Formation and fates of nitrosamines and their formation potentials from a surface water source to drinking water treatment plants in Southern Taiwan.

    Science.gov (United States)

    Chen, Wei-Hsiang; Wang, Chung-Ya; Huang, Tsung-Hsien

    2016-10-01

    Nitrosamines are toxic and emerging disinfection byproducts. In this study, three drinking water treatment plants (DWTPs) in southern Taiwan treating the same source water in Gaoping River with comparable technologies were selected. The objective was to evaluate the formation and fates of six nitrosamines and their formation potentials (FPs) from a surface water source to drinking water. Albeit decreased further downstream in the river, four nitrosamine-FPs were observed in the source water due to anthropogenic pollution in the upstream areas. In the DWTPs, nitrosamines were formed and NDMA was the main species. While high organic carbon concentrations indicated elevated nitrosamine-FPs in the source water, NDMA formation in the DWTPs was more positively associated with reductions of water parameters that quantify organic matters with double bonded ring structures. Although precursor removal via pre-oxidation is a viable approach to limit nitrosamine formation during post-disinfection, this study clearly indicates that a great portion of NDMA in treated water has been formed in the 1st oxidation step of drinking water treatment. The pre-oxidation simulations in the lab demonstrated the impact of pre-chlorination on nitrosamine formation. Given the limited removal in conventional treatment processes, avoiding nitrosamine-FPs in sources and/or nitrosamine formation during pre-oxidation become important issues to control the threats of nitrosamines in drinking water. Under current circumstance in which pre-oxidation is widely used to optimize the treatment effectiveness in many DWTPs, its adverse effect by forming nitrosamines needs to be carefully minimized and using technologies other than pre-chlorination (e.g., pre-ozonation) may be considered. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Monitoring nitrosamines in large water distribution systems and their removal using cyclodextrin polyurethanes

    OpenAIRE

    2010-01-01

    M.Sc. The disinfection of drinking water is an important step in the water treatment process. However, toxic (unwanted) disinfection by-products (DBPs) are often produced during the disinfection of drinking water. One such group of DBPs are the nitrosamines such as N-Nitrosodimethylamine (NDMA). Nitrosamines, particularly NDMA, are highly carcinogenic, mutagenic and teratogenic. The US Environmental Protection Agency (USEPA) placed these compounds into the group B2, which indicates compoun...

  1. Prospective study of meat intake and dietary nitrates, nitrites, and nitrosamines and risk of adult glioma123

    Science.gov (United States)

    Holick, Crystal N; Batchelor, Tracy T; Giovannucci, Edward; Hunter, David J

    2009-01-01

    Background: The hypothesis that nitrosamine exposure may increase the risk of glioma has been circulating for several decades, but testing it has been difficult because of the ubiquitous nature of nitrosamine exposure. Diet has been the focus of many studies because it can substantially influence nitrosamine exposure, mostly from the endogenous formation of nitrosamines based on intake of nitrite and nitrate. Objective: The objective was to examine the relation between intakes of meats, nitrate, nitrite, and 2 nitrosamines [nitrosodimethylamine (NDMA) and nitrosopyrolidine (NPYR)] and glioma risk in a prospective analysis. Methods: Data from 3 US prospective cohort studies were combined for this analysis; 335 glioma cases were diagnosed during ≤24 y of follow-up. Dietary intake was assessed with food-frequency questionnaires. Nitrate, nitrite, and nitrosamine values were calculated based on published values of these nutrients in various foods over different periods in time. Cox proportional hazards models were used to estimate incidence rate ratios (RRs) and 95% CIs. Estimates from each cohort were pooled by using a random-effects model. Results: Risk of glioma was not elevated among individuals in the highest intake category of total processed meats (RR: 0.92; 95% CI: 0.48, 1.77), nitrate (RR: 1.02; 95% CI: 0.66, 1.58), nitrites (RR: 1.26; 95% CI: 0.89, 1.79), or NDMA (RR: 0.88; 95% CI: 0.57, 1.36) compared with the lowest category. No effect modification was observed by intake of vitamins C or E or other antioxidant measures. Conclusion: We found no suggestion that intake of meat, nitrate, nitrite, or nitrosamines is related to the risk of glioma. PMID:19587083

  2. Electrochemical destruction of nitrosamines

    Energy Technology Data Exchange (ETDEWEB)

    Lejen, T; Volchek, K; Ladanowski, C; Velicogna, D; Whittaker, H [Environment Canada, Ottawa, ON (Canada). Emergencies Engineering Div.

    1996-09-01

    Treatment conditions for the electrolytic destruction of nitrosamines were studied. The joint investigation between Canada and the Ukraine was part of an assessment of hazardous contaminants at former Soviet ICBM missile sites. The electrochemical destruction of N-dimethylnitrosamines (NDMA) on carbon/platinum electrodes was studied under basic and acidic conditions by UV spectroscopy, gas chromatography, mass spectroscopy, and colorimetry. Experiments with a 100 ppm NDMA solution showed that electrolytic-reduction was pH sensitive within a range of pH 0.5 to 4.0. Electrolysis was effective for the reduction of NDMA in strong acidic conditions. 30 refs., 1 tab., 4 figs.

  3. Simultaneous removal of ammonia and N-nitrosamine precursors from high ammonia water by zeolite and powdered activated carbon.

    Science.gov (United States)

    Xue, Runmiao; Donovan, Ariel; Zhang, Haiting; Ma, Yinfa; Adams, Craig; Yang, John; Hua, Bin; Inniss, Enos; Eichholz, Todd; Shi, Honglan

    2018-02-01

    When adding sufficient chlorine to achieve breakpoint chlorination to source water containing high concentration of ammonia during drinking water treatment, high concentrations of disinfection by-products (DBPs) may form. If N-nitrosamine precursors are present, highly toxic N-nitrosamines, primarily N-nitrosodimethylamine (NDMA), may also form. Removing their precursors before disinfection should be a more effective way to minimize these DBPs formation. In this study, zeolites and activated carbon were examined for ammonia and N-nitrosamine precursor removal when incorporated into drinking water treatment processes. The test results indicate that Mordenite zeolite can remove ammonia and five of seven N-nitrosamine precursors efficiently by single step adsorption test. The practical applicability was evaluated by simulation of typical drinking water treatment processes using six-gang stirring system. The Mordenite zeolite was applied at the steps of lime softening, alum coagulation, and alum coagulation with powdered activated carbon (PAC) sorption. While the lime softening process resulted in poor zeolite performance, alum coagulation did not impact ammonia and N-nitrosamine precursor removal. During alum coagulation, more than 67% ammonia and 70%-100% N-nitrosamine precursors were removed by Mordenite zeolite (except 3-(dimethylaminomethyl)indole (DMAI) and 4-dimethylaminoantipyrine (DMAP)). PAC effectively removed DMAI and DMAP when added during alum coagulation. A combination of the zeolite and PAC selected efficiently removed ammonia and all tested seven N-nitrosamine precursors (dimethylamine (DMA), ethylmethylamine (EMA), diethylamine (DEA), dipropylamine (DPA), trimethylamine (TMA), DMAP, and DMAI) during the alum coagulation process. Copyright © 2017. Published by Elsevier B.V.

  4. Transnitrosation of alicyclic N-nitrosamines containing a sulfur atom.

    Science.gov (United States)

    Inami, Keiko; Kondo, Sonoe; Ono, Yuta; Saso, Chiharu; Mochizuki, Masataka

    2013-12-15

    Aromatic and aliphatic nitrosamines are known to transfer a nitrosonium ion to another amine. The transnitrosation of alicyclic N-nitroso compounds generates S-nitrosothiols, which are potential nitric oxide donors in vivo. In this study, certain alicyclic N-nitroso compounds based on non-mutagenic N-nitrosoproline or N-nitrosothioproline were synthesised, and the formation of S-nitrosoglutathione (GSNO) was quantified under acidic conditions. We then investigated the effect of a sulfur atom as the substituent and as a ring component on the GSNO formation. In the presence of thiourea under acidic conditions, GSNO was formed from N-nitrosoproline and glutathione, and an N-nitroso compound containing a sulfur atom and glutathione produced GSNO without thiourea. The quantity of GSNO derived from the reaction of the N-nitrosamines containing a sulfur atom and glutathione was higher than that from the N-nitrosoproline and glutathione plus thiourea. Among the analogues that contained a sulfur atom either in the ring or as a substituent, the thiazolidines produced a slightly higher quantity of GSNO than the analogue with a thioamide group. A compound containing sulfur atoms both in the ring and as a substituent exhibited the highest activity for GSNO formation among the alicyclic N-nitrosamines tested. The results indicate that the intramolecular sulfur atom plays an important role in the transnitrosation via alicyclic N-nitroso compounds to form GSNO. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  5. Nitrosamines in new automobiles

    Energy Technology Data Exchange (ETDEWEB)

    Fine, D H; Reisch, J; Rounbehler, D P

    1980-01-01

    The volatile nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosomorpholine (NMOR), N-nitrosodiethylamine (NDEA) and possibly N-nitrosodibutylamine (NDBA) have been found to be present as airborne pollutants in the interiors of new (1979 model) automobiles. In the 38 automobiles tested, the levels ranged from 0.07 to 0.83 micrograms/m3 (average 0.3 micrograms/m3) for NDMA, from 0.07 to 2.5 micrograms/m3 (average 0.67 micrograms/m3) for NMOR, from 0.04 to 0.39 micrograms/m3 (average 0.11 micrograms/m3) for NDEA and trace levels (less than 0.01 micrograms/m3) for NDMA.

  6. Role of membrane fouling substances on the rejection of N-nitrosamines by reverse osmosis.

    Science.gov (United States)

    Fujioka, Takahiro; Kodamatani, Hitoshi; Aizawa, Hidenobu; Gray, Stephen; Ishida, Kenneth P; Nghiem, Long D

    2017-07-01

    The impact of fouling substances on the rejection of four N-nitrosamines by a reverse osmosis (RO) membrane was evaluated by characterizing individual organic fractions in a secondary wastewater effluent and deploying a novel high-performance liquid chromatography-photochemical reaction-chemiluminescence (HPLC-PR-CL) analytical technique. The HPLC-PR-CL analytical technique allowed for a systematic examination of the correlation between the fouling level and the permeation of N-nitrosamines in the secondary wastewater effluent and synthetic wastewaters through an RO membrane. Membrane fouling caused by the secondary wastewater effluent led to a notable decrease in the permeation of N-nitrosodimethylamine (NDMA) while a smaller but nevertheless discernible decrease in the permeation of N-nitrosomethylethylamine (NMEA), N-nitrosopyrrolidine (NPYR) and N-nitrosomorpholine (NMOR) was also observed. Fluorescence spectrometry analysis revealed that major foulants in the secondary wastewater effluent were humic and fulvic acid-like substances. Analysis using the size exclusion chromatography technique also identified polysaccharides and proteins as additional fouling substances. Thus, further examination was conducted using solutions containing model foulants (i.e., sodium alginate, bovine serum albumin, humic acid and two fulvic acids). Similar to the secondary wastewater effluent, membrane fouling with fulvic acid solutions resulted in a decrease in N-nitrosamine permeation. In contrast, membrane fouling with the other model foulants resulted in a negligible impact on N-nitrosamine permeation. Overall, these results suggest that the impact of fouling on the permeation of N-nitrosamines by RO is governed by specific small organic fractions (e.g. fulvic acid-like organics) in the secondary wastewater effluent. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Monitoring the prevalence of nitrosamines in South African waters and their removal using cyclodextrin polyurethanes

    Science.gov (United States)

    Mhlongo, Sthembile H.; Mamba, Bhekie B.; Krause, Rui W.

    The prevalence of nitrosamines, especially N-nitrosodimethylamine (NDMA), was monitored in three South African water supplies. NDMA a disinfection by-product (DBP) and potent carcinogen, has recently been detected in many drinking water supplies internationally. Besides direct industrial or human-derived contamination, nitrosodimethylamine can be formed through a chemical reaction between monochloroamine and an organic based compound such as dimethylamine which is frequently detected in surface water. It has been suggested that chloramination of surface waters with a high concentration of dissolved organic carbon (DOC) could result in elevated NDMA formation. Growing evidence suggests that NDMA occurs more frequently and at higher concentrations in drinking water systems that practise chloramination compared to systems that use chlorination. In gauging the extent of water contamination by nitrosamines in water distribution systems, especially NDMA, water samples collected from three different water treatment plants that practise chemical drinking water disinfection were qualitatively analysed for the presence of nitrosamines. Solid phase microextraction (SPME) was employed in the extraction of nitrosamines from the water samples and gas chromatography-mass spectrometry (GC-MS), was used in the analysis of the water samples. Trace amounts of NDMA were detected at one of the water treatment plants and in the distribution network. The application of water-insoluble cyclodextrin (CD) polymers in the removal of nitrosamines and potential amine precursors from the water samples was tested. Quantitative removal of NDMA (based on peak area) from the water samples was achieved which suggests that in the water treatment train the use of these nanosponges can be applied in the mitigation of trace contaminants such as NDMA.

  8. Mechanistic Insight into the Degradation of Nitrosamines via Aqueous-Phase UV Photolysis or a UV-Based Advanced Oxidation Process: Quantum Mechanical Calculations.

    Science.gov (United States)

    Minakata, Daisuke; Coscarelli, Erica

    2018-02-28

    Nitrosamines are a group of carcinogenic chemicals that are present in aquatic environments that result from byproducts of industrial processes and disinfection products. As indirect and direct potable reuse increase, the presence of trace nitrosamines presents challenges to water infrastructures that incorporate effluent from wastewater treatment. Ultraviolet (UV) photolysis or UV-based advanced oxidation processes that produce highly reactive hydroxyl radicals are promising technologies to remove nitrosamines from water. However, complex reaction mechanisms involving radicals limit our understandings of the elementary reaction pathways embedded in the overall reactions identified experimentally. In this study, we perform quantum mechanical calculations to identify the hydroxyl radical-induced initial elementary reactions with N -nitrosodimethylamine (NDMA), N -nitrosomethylethylamine, and N -nitrosomethylbutylamine. We also investigate the UV-induced NDMA degradation mechanisms. Our calculations reveal that the alkyl side chains of nitrosamine affect the reaction mechanism of hydroxyl radicals with each nitrosamine investigated in this study. Nitrosamines with one- or two-carbon alkyl chains caused the delocalization of the electron density, leading to slower subsequent degradation. Additionally, three major initial elementary reactions and the subsequent radical-involved reaction pathways are identified in the UV-induced NDMA degradation process. This study provides mechanistic insight into the elementary reaction pathways, and a future study will combine these results with the kinetic information to predict the time-dependent concentration profiles of nitrosamines and their transformation products.

  9. Mechanistic Insight into the Degradation of Nitrosamines via Aqueous-Phase UV Photolysis or a UV-Based Advanced Oxidation Process: Quantum Mechanical Calculations

    Directory of Open Access Journals (Sweden)

    Daisuke Minakata

    2018-02-01

    Full Text Available Nitrosamines are a group of carcinogenic chemicals that are present in aquatic environments that result from byproducts of industrial processes and disinfection products. As indirect and direct potable reuse increase, the presence of trace nitrosamines presents challenges to water infrastructures that incorporate effluent from wastewater treatment. Ultraviolet (UV photolysis or UV-based advanced oxidation processes that produce highly reactive hydroxyl radicals are promising technologies to remove nitrosamines from water. However, complex reaction mechanisms involving radicals limit our understandings of the elementary reaction pathways embedded in the overall reactions identified experimentally. In this study, we perform quantum mechanical calculations to identify the hydroxyl radical-induced initial elementary reactions with N-nitrosodimethylamine (NDMA, N-nitrosomethylethylamine, and N-nitrosomethylbutylamine. We also investigate the UV-induced NDMA degradation mechanisms. Our calculations reveal that the alkyl side chains of nitrosamine affect the reaction mechanism of hydroxyl radicals with each nitrosamine investigated in this study. Nitrosamines with one- or two-carbon alkyl chains caused the delocalization of the electron density, leading to slower subsequent degradation. Additionally, three major initial elementary reactions and the subsequent radical-involved reaction pathways are identified in the UV-induced NDMA degradation process. This study provides mechanistic insight into the elementary reaction pathways, and a future study will combine these results with the kinetic information to predict the time-dependent concentration profiles of nitrosamines and their transformation products.

  10. Adsorption of parent nitrosamine on the nanocrystaline M-ZSM-5 ...

    Indian Academy of Sciences (India)

    interactions were predicted from adsorption of nitrosamine on the M-zeolite clusters. The comparison of inter- ... 1. Introduction. Approximately 60–90% of human cancers are ... catalysts that have been widely used in the adsorption of serious ...

  11. Occurrence of nitrate, nitrite and volatile nitrosamines in certain feedstuffs and animal products.

    Science.gov (United States)

    Ologhobo, A D; Adegede, H I; Maduagiwu, E N

    1996-01-01

    Nitrate, nitrite and nitrosamines were analysed in poultry feeds, meat and eggs. The poultry meat was boiled and roasted while the eggs were raw and boiled, and the effects of these processing treatments on the level of these compounds were investigated. Nitrate levels in the meat samples were significantly (P Nitrite levels were also reduced significantly by processing (P Nitrite levels were generally low in all feed samples. Nitrosamines were not detected in any of the feed samples and in the meat samples except in two samples of boiled meat which contained 0.001 g/kg each.

  12. Variation of levels and distribution of N-nitrosamines in different seasons in drinking waters of East China.

    Science.gov (United States)

    Li, Ting; Yu, Dian; Xian, Qiming; Li, Aimin; Sun, Cheng

    2015-08-01

    We surveyed the occurrence of nine N-nitrosamine species in ten bottled drinking waters from supermarket and other water samples including raw waters, finished waters, and distribution system waters from nine municipal drinking water treatment plants in eight cities of Jiangsu Province, East China. N-nitrosodimethylamine (NDMA) was detected in one of ten bottled drinking water samples at concentration of 4.8 ng/L and N-nitrosomorpholine (NMor) was detected in four of the ten bottles with an average concentration and a standard deviation of 16 ± 15 ng/L. The levels of nitrosamines in the distribution system water samples collected during summer season ranged from below detection limit (BDL) to 5.4 ng/L for NDMA, BDL to 9.5 ng/L for N-nitrosomethylethylamine (NMEA), BDL to 2.7 ng/L for N-nitrosodiethylamine (NDEA) and BDL to 8.5 ng/L for N-nitrosopyrrolidine (NPyr). Samples of distribution system waters collected in winter season had levels of nitrosamines ranged from BDL to 45 ng/L for NDMA, BDL to 5.2 ng/L for NPyr, and BDL to 309 ng/L for N-nitrosopiperidine (NPip). A positive correlation of the concentration of NDMA as well as the total nine N-nitrosamines between finished waters and distribution system waters was observed. Both dissolved organic carbon and nitrite were found to correlate linearly with N-nitrosamine levels in raw waters.

  13. Gastritis, nitrosamines, and gastric cancer

    Energy Technology Data Exchange (ETDEWEB)

    Stemmermann, G.N.; Mower, H.

    1981-01-01

    Gastritis is associated with peptic ulcer, gastroenterostomy, pernicious anemia, and exposure to nitrosamines. Once established, the process may be self-perpetuating, resulting in atrophy, metaplasia, dysplasia, and neoplasia. This can be explained by the process of endogenous nitrosation of amines in the inflamed gastric mucosa. Evidence is presented to support this hypothesis. Several drugs given parenterally have been identified as mutagenic nitroso compounds in homogenates of human and canine antral mucosa. Nitrite for this process is apparently derived from the inflamed mucosa. Different amines appear to be nitrosated at different places in the antrum, suggesting the presence of site-specific enzymes that control these reactions.

  14. Influence of putrescine, cadaverine, spermidine or spermine on the formation of N-nitrosamine in heated cured pork meat.

    Science.gov (United States)

    Drabik-Markiewicz, G; Dejaegher, B; De Mey, E; Kowalska, T; Paelinck, H; Vander Heyden, Y

    2011-06-15

    The influence of biogenic amines (i.e. putrescine, cadaverine, spermidine and spermine) on the N-nitrosamine formation in heated cured lean meat was studied in the presence or absence of sodium nitrite and at different meat processing temperatures. Experimental evidence was produced using gas chromatography with thermal energy analysis detection (GC-TEA). Concentration of N-nitrosamines was modelled as a function of the temperature and the nitrite concentration for two situations, i.e. presence or absence of added biogenic amines to the meat. The significance of the influence of the changing parameters was evaluated by ANOVA (Analysis of Variance). It was found that higher processing temperatures and higher added amounts of sodium nitrite increase the yields of N-nitrosodimethylamine (NDMA) and N-nitrosopiperidine (NPIP). Spermidine and putrescine amplify the formation of NDMA, but spermine and cadeverine do not influence the formation of this N-nitrosamine. Spermidine and cadeverine cause a significant increase of NPIP. Beside N-nitrosopyrrolidine (NPYR) in some rare cases, no other volatile N-nitrosamines are detected. Copyright © 2010 Elsevier Ltd. All rights reserved.

  15. Separation Of N-Nitrosamines By Micellar Electrokinetic Chromatography

    International Nuclear Information System (INIS)

    Nur Amira Md Ali; Mohd Marsin Sanagi; Wan Aini Wan Ibrahim

    2014-01-01

    A simple and rapid micellar electrokinetic chromatography (MEKC) method was developed for separation of three selected N-Nitrosamines namely N-nitrosodipropylamine (NDPA), N-nitrosodibutylamine (NDBA) and N-nitrosodiphenylamine (NDPhA). The effects of composition of the buffer and its pH, concentration of surfactants on the separation and migration times of nitrosamines were investigated. The instrumental variables affecting sensitivity and resolution such as power supply and injection mode were carefully optimized. The best separation was achieved using 40 mM sodium dodecyl sulfate (SDS) as a surfactant in 10 mM phosphate buffer (pH 8.0) at a temperature of 25 degree Celsius, applied voltage of 29 kV, wavelength of 230 nm and electrokinetic injection of 9 s at 5 kV within 10 min analysis time. Excellent linearity was obtained in the concentration range of 2 to 100 μg/ mL with coefficients of determination, r 2 ≥0.979. This method showed good reproducibility with relative standard deviation (RSDs) value ranging from 2.46 % to 6.61 %. The limits of detection (LOD) and limits of quantification (LOQ) ranged from 0.16 to 0.43 μg/ mL and 0.54 to 1.44 μg/mL respectively. (author)

  16. Evaluation of the influence of proline, hydroxyproline or pyrrolidine in the presence of sodium nitrite on N-nitrosamine formation when heating cured meat.

    Science.gov (United States)

    Drabik-Markiewicz, G; Dejaegher, B; De Mey, E; Impens, S; Kowalska, T; Paelinck, H; Vander Heyden, Y

    2010-01-11

    N-nitrosamines are meant to be probable or possible carcinogenic components, possibly formed out of a reaction between nitrite and N-containing substances such as amino acids and secondary amines. Nitrite is often used for processing meat products because of its colouring and antimicrobial properties. During this experimental setup, the influence of proline, hydroxyproline or pyrrolidine on N-nitrosamine formation in meat samples was evaluated. The N-nitrosamines concentrations were measured with gas chromatography-thermal energy analyzer. Only the concentrations of N-nitrosodimethylamine and N-nitrosopyrrolidine were found above the limit of detection in a number of tested experimental conditions. The concentration of these two N-nitrosamines was modelled as a function of temperature and nitrite concentration for different situations (presence or absence of added natural N-containing meat components). It could be concluded that proline and pyrrolidine promoted the formation of N-nitrosopyrrolidine. It could also be confirmed that the higher the temperature of the meat processing procedure and the higher the sodium nitrite amounts added, the higher were the yields of the respective N-nitrosamines.

  17. Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the short willet food frequency questionnaire

    OpenAIRE

    Griesenbeck, John S; Steck, Michelle D; Huber, John C; Sharkey, Joseph R; Rene, Antonio A; Brender, Jean D

    2009-01-01

    Abstract Background Studies have suggested that nitrates, nitrites, and nitrosamines have an etiologic role in adverse pregnancy outcomes and chronic diseases such as cancer. Although an extensive body of literature exists on estimates of these compounds in foods, the extant data varies in quality, quantified estimates, and relevance. Methods We developed estimates of nitrates, nitrites, and nitrosamines for food items listed in the Short Willet Food Frequency Questionnaire (WFFQ) as adapted ...

  18. [The elaboration of gas chromatographic method of the determination of N-nitrosamines (N-nitrosodimethylamine, N-nitrosodiethylamine) in biological samples (urine)].

    Science.gov (United States)

    Zaytseva, N V; Ulanova, T S; Nurislamova, T V; Popova, N A

    2014-01-01

    The issues of the elaboration of a method for the determination of N-nitrosamines (N-nitrosodimethylamine, N-nitrosodiethylamine) in urine by means of the method of capillary gas chromatography with the use of a thermionic detector are considered. There were performed investigations on the study of the efficacy of the extraction of N-nitrosamines from the urine by steam distillation and gas chromatographic detection of headspace. With the aim of the maximal recovery of N-nitrosamines from the urine and setting parameters of the extraction two method were used to prepare the bioassay for the analysis the alkalization with potassium hydroxide and the addition of salting out reagent--neutral salts of alkali and alkaline earth metals. During the process of performed studies there was found that the greatest degree of extraction of N-nitrosamines from the urine by the method of headspace analysis is achieved if using the salting-out agent in an amount of 16 g of sodium sulfate and for N-nitrosodimethylamine is 99%, for N-nitrosodiethylamine--100%.

  19. The Role of Hydroxylamine as a Nitrification Intermediate in N-nitrosamine Formation

    Science.gov (United States)

    The formation of N-nitrosamines, and in particular N-nitrosodimethylamine (NDMA), in drinking water systems that use chloramines is a concern because of their potential carcinogenicity and occurrences in finished waters at toxicologically relevant levels. The widely accepted mech...

  20. Detection and Occurrence of N-Nitrosamines in Archived Biosolids from the Targeted National Sewage Sludge Survey of the U.S. Environmental Protection Agency

    Science.gov (United States)

    2015-01-01

    The occurrence of eight carcinogenic N-nitrosamines in biosolids from 74 wastewater treatment plants (WWTPs) in the contiguous United States was investigated. Using liquid chromatography-tandem mass spectrometry, seven nitrosamines [(N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine, N-nitrosodi-n-propylamine (NDPA), N-nitrosodibutylamine, N-nitrosopyrrolidine, N-nitrosopiperidine (NPIP), and N-nitrosodiphenylamine (NDPhA)] were detected with varying detection frequency (DF) in 88% of the biosolids samples (n = 80), with five of the seven being reported here for the first time in biosolids. While rarely detected (DF 3%), NDMA was the most abundant compound at an average concentration of 504 ± 417 ng/g dry weight of biosolids. The most frequently detected nitrosamine was NDPhA (0.7—147 ng/g) with a DF of 79%, followed by NDPA (7–505 ng/g) and NPIP (51–1185 ng/g) at 21% and 11%, respectively. The DF of nitrosamines in biosolids was positively correlated with their respective n-octanol–water partition coefficients (R2 = 0.65). The DF and sum of mean concentrations of nitrosamines in biosolids increased with the treatment capacity of WWTPs. Given their frequent occurrence in nationally representative samples and the amount of U.S. biosolids being applied on land as soil amendment, this study warrants more research into the occurrence and fate of nitrosamines in biosolids-amended soils in the context of crop and drinking water safety. PMID:24697330

  1. An inline ion-exchange system in a chemiluminescence-based analyzer for direct analysis of N-nitrosamines in treated wastewater.

    Science.gov (United States)

    Kodamatani, Hitoshi; Roback, Shannon L; Plumlee, Megan H; Ishida, Kenneth P; Masunaga, Hiroto; Maruyama, Noboru; Fujioka, Takahiro

    2018-04-13

    A newly developed, ion exchange-based inline pretreatment system was used to mitigate the effect of background constituents in natural water and treated wastewater to achieve rapid, reliable, and sensitive analysis of N-nitrosamines. The pretreatment system (anion exchange module, AEM) was incorporated into a high-performance liquid chromatograph (HPLC) coupled with a photochemical reactor (PR) and chemiluminescence (CL) detector (HPLC-PR-CL), which can analyze four hydrophilic N-nitrosamines at ng/L levels. This system requires no pre-concentration of the water sample nor the use of deuterated surrogates, unlike other conventional N-nitrosamine analytical techniques. The AEM converted anions in the eluent to hydroxide ions after HPLC separation and increased eluent pH, allowing for the subsequent photochemical reactions, which are otherwise achieved by pH conditioning with an additional dosing pump of basic chemical. The AEM also removed anionic interfering compounds (e.g. nitrate) from the samples, allowing for improved N-nitrosamine analysis in treated wastewater. The operating conditions of the AEM and PR were optimized to obtain sensitive and stable analytical performance. As a result, the lowest-concentration minimum reporting levels of N-nitrosodimethylamine, N-nitrosomorpholine, N-nitrosomethylethylamine, and N- nitrosopyrrolidine using the optimized system were 0.42, 0.54, 0.58, and 1.4 ng/L, respectively. The improved analytical method was validated by comparing the results with a conventional method based on gas chromatography coupled with a mass spectrometric ion trap detector. These results indicated that HPLC-PR-CL equipped with an inline AEM can be competitively applied as a rapid analytical technique for the determination of N-nitrosamines in various water matrices. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Maternal dietary intake of nitrates, nitrites and nitrosamines and selected birth defects in offspring: a case-control study.

    Science.gov (United States)

    Huber, John C; Brender, Jean D; Zheng, Qi; Sharkey, Joseph R; Vuong, Ann M; Shinde, Mayura U; Griesenbeck, John S; Suarez, Lucina; Langlois, Peter H; Canfield, Mark A; Romitti, Paul A; Weyer, Peter J

    2013-03-21

    Dietary intake of nitrates, nitrites, and nitrosamines can increase the endogenous formation of N-nitroso compounds in the stomach. Results from animal studies suggest that these compounds might be teratogenic. We examined the relationship between maternal dietary intake of nitrates, nitrites (including plant and animal sources as separate groups), and nitrosamines and several types of birth defects in offspring. For this population-based case-control study, data from a 58-question food frequency questionnaire, adapted from the short Willett Food Frequency Questionnaire and administered as part of the National Birth Defects Prevention Study (NBDPS), were used to estimate daily intake of dietary nitrates, nitrites, and nitrosamines in a sample of 6544 mothers of infants with neural tube defects (NTD)s, oral clefts (OC)s, or limb deficiencies (LD)s and 6807 mothers of unaffected control infants. Total daily intake of these compounds was divided into quartiles based on the control mother distributions. Odds ratios (OR)s and 95% confidence intervals (CI)s were estimated using logistic regression; estimates were adjusted for maternal daily caloric intake, maternal race-ethnicity, education, dietary folate intake, high fat diet (>30% of calories from fat), and state of residence. While some unadjusted ORs for NTDS had 95% (CI)s that excluded the null value, none remained significant after adjustment for covariates, and the effect sizes were small (adjusted odds ratios [aOR]nitrate, nitrite, and nitrosamines.

  3. Public health implications of smokeless tobacco use as a harm reduction strategy.

    Science.gov (United States)

    Savitz, David A; Meyer, Roger E; Tanzer, Jason M; Mirvish, Sidney S; Lewin, Freddi

    2006-11-01

    Harm reduction strategies involve promoting a product that has adverse health consequences as a substitute for one that has more severe adverse health consequences. Smokeless tobacco low in nitrosamine content offers potential benefits in reducing smoking prevalence rates. Possible harm arises from the potential for such products to serve as a gateway to more harmful tobacco products, public misinterpretation of "less harmful" as "safe," distraction from the public health goal of tobacco elimination, and ethical issues involved in advising those marketing these harmful products. We offer a research agenda to provide a stronger basis for evaluating the risks and benefits of smokeless tobacco as a means of reducing the adverse health effects of tobacco.

  4. The Role of Hydroxylamine as a Nitrification Intermediate in N-Nitrosamine Formation- Indianapolis

    Science.gov (United States)

    The formation of N-nitrosamines, and in particular N-nitrosodimethylamine (NDMA), in drinking water systems that use chloramines is a concern because of their potential carcinogenicity and occurrences in finished waters at toxicologically relevant levels. The widely accepted mech...

  5. Intragastric nitrites, nitrosamines, and bacterial overgrowth during cimetidine treatment.

    OpenAIRE

    Stockbrugger, R W; Cotton, P B; Eugenides, N; Bartholomew, B A; Hill, M J; Walters, C L

    1982-01-01

    A six week course of cimetidine (1 g/day) healed peptic ulcers in 20 of 23 patients (14 with duodenal ulcer, nine with gastric ulcer). Reduction of basal acid output by 73% and peak acid output by 36% led to a rise in concentrations of intragastric aerobic bacteria and nitrate-reducing bacteria. While the mean intragastric concentration of nitrate was unchanged by treatment, there were statistically significant rises in nitrite and N-nitrosamine concentrations. The conversion from nitrates to...

  6. Drinking water as a proportion of total human exposure to volatile N-nitrosamines.

    Science.gov (United States)

    Hrudey, Steve E; Bull, Richard J; Cotruvo, Joseph A; Paoli, Greg; Wilson, Margaret

    2013-12-01

    Some volatile N-nitrosamines, primarily N-nitrosodimethylamine (NDMA), are recognized as products of drinking water treatment at ng/L levels and as known carcinogens. The U.S. EPA has identified the N-nitrosamines as contaminants being considered for regulation as a group under the Safe Drinking Water Act. Nitrosamines are common dietary components, and a major database (over 18,000 drinking water samples) has recently been created under the Unregulated Contaminant Monitoring Rule. A Monte Carlo modeling analysis in 2007 found that drinking water contributed less than 2.8% of ingested NDMA and less than 0.02% of total NDMA exposure when estimated endogenous formation was considered. Our analysis, based upon human blood concentrations, indicates that endogenous NDMA production is larger than expected. The blood-based estimates are within the range that would be calculated from estimates based on daily urinary NDMA excretion and an estimate based on methylated guanine in DNA of lymphocytes from human volunteers. Our analysis of ingested NDMA from food and water based on Monte Carlo modeling with more complete data input shows that drinking water contributes a mean proportion of the lifetime average daily NDMA dose ranging from between 0.0002% and 0.001% for surface water systems using free chlorine or between 0.001% and 0.01% for surface water systems using chloramines. The proportions of average daily dose are higher for infants (zero to six months) than other age cohorts, with the highest mean up to 0.09% (upper 95th percentile of 0.3%). © 2013 Society for Risk Analysis.

  7. Antimutagenic effects of betel leaf extract against the mutagenicity of two tobacco-specific N-nitrosamines.

    Science.gov (United States)

    Padma, P R; Amonkar, A J; Bhide, S V

    1989-03-01

    Epidemiological studies have implicated chewing tobacco alone to be more hazardous than chewing tobacco with betel quid. Experimental studies have shown that betel leaf is antimutagenic against standard mutagens like benzo[a]pyrene and dimethylbenz[a]anthracene. Since the tobacco-specific N-nitrosamines (TSNA) are the only carcinogens present in unburnt forms of tobacco, including chewing tobacco, we tested the effect of an extract of betel leaf against the mutagenicity of the two important TSNA, viz., N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, using the Ames Salmonella/microsome assay with TA100 +S9 and the in vivo micronucleus test. In both the test systems it was observed that betel leaf extract suppressed the mutagenic effects of both the nitrosamines to a significant extent.

  8. Nitrosamines in bacon: a case study of balancing risks.

    OpenAIRE

    McCutcheon, J W

    1984-01-01

    Nitrite has been used for centuries to preserve, color, and flavor meat. Today, about 10 billion pounds of cured meat products are produced annually, accounting for some one-tenth of the American food supply. Regulators became concerned about the safety of using nitrite in the early 1960s when studies showed the presence of carcinogenic nitrosamines in cured meat products. In the early 1970s, a study at the Massachusetts Institute of Technology implicated nitrite itself as a carcinogen. As st...

  9. Kinetics of nitrosamine and amine reactions with NO3 radical and ozone related to aqueous particle and cloud droplet chemistry

    Science.gov (United States)

    Weller, Christian; Herrmann, Hartmut

    2015-01-01

    Aqueous phase reactivity experiments with the amines dimethylamine (DMA), diethanolamine (DEA) and pyrrolidine (PYL) and their corresponding nitrosamines nitrosodimethylamine (NDMA), nitrosodiethanolamine (NDEA) and nitrosopyrrolidine (NPYL) have been performed. NO3 radical reaction rate coefficients for DMA, DEA and PYL were measured for the first time and are 3.7 × 105, 8.2 × 105 and 8.7 × 105 M-1 s-1, respectively. Rate coefficients for NO3 + NDMA, NDEA and NPYL are 1.2 × 108, 2.3 × 108 and 2.4 × 108 M-1 s-1. Compared to OH radical rate coefficients for reactions with amines, the NO3 radical will most likely not be an important oxidant but it is a potential nighttime oxidant for nitrosamines in cloud droplets or deliquescent particles. Ozone is unreactive towards amines and nitrosamines and upper limits of rate coefficients suggest that aqueous ozone reactions are not important in atmospheric waters.

  10. Determination of volatile nitrosamines in grilled lamb and vegetables using comprehensive gas chromatography - nitrogen chemiluminescence detection.

    Science.gov (United States)

    Kocak, D; Ozel, M Z; Gogus, F; Hamilton, J F; Lewis, A C

    2012-12-15

    The grilling of meat may generate dangerous levels of mutagenic and carcinogenic nitrosamines (NAs). Meat and vegetable samples underwent a two-step solid-phase extraction before analysis by comprehensive gas chromatography with a nitrogen chemiluminescence detection system (GCxGC-NCD). The GCxGC-NCD method showed high selectivity, sensitivity and equimolarity in its response to six specific NAs. NA contamination of charcoal-grilled lamb at various stages of cooking and with various fat contents and also charcoal-grilled vegetables were investigated. The grilling of lamb on unready charcoal resulted in the formation of considerable quantities of NAs. Grilling lamb on properly prepared, ready charcoal resulted in an increase in total concentrations of six NAs from 0 to 4.51 μg kg(-1) over a period of 16 min. Increasing the fat content of the grilled lamb from 5% to 20% caused a modest increase in total concentrations of the six investigated NAs from 4.51 to 5.30 μg kg(-1). Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Maternal characteristics associated with the dietary intake of nitrates, nitrites, and nitrosamines in women of child-bearing age: a cross-sectional study.

    Science.gov (United States)

    Griesenbeck, John S; Brender, Jean D; Sharkey, Joseph R; Steck, Michelle D; Huber, John C; Rene, Antonio A; McDonald, Thomas J; Romitti, Paul A; Canfield, Mark A; Langlois, Peter H; Suarez, Lucina

    2010-02-19

    Multiple N-nitroso compounds have been observed in animal studies to be both mutagenic and teratogenic. Human exposure to N-nitroso compounds and their precursors, nitrates and nitrites, can occur through exogenous sources, such as diet, drinking water, occupation, or environmental exposures, and through endogenous exposures resulting from the formation of N-nitroso compounds in the body. Very little information is available on intake of nitrates, nitrites, and nitrosamines and factors related to increased consumption of these compounds. Using survey and dietary intake information from control women (with deliveries of live births without major congenital malformations during 1997-2004) who participated in the National Birth Defects Prevention Study (NBDPS), we examined the relation between various maternal characteristics and intake of nitrates, nitrites, and nitrosamines from dietary sources. Estimated intake of these compounds was obtained from the Willet Food Frequency Questionnaire as adapted for the NBDPS. Multinomial logistic regression models were used to estimate odds ratios and 95% confidence intervals for the consumption of these compounds by self-reported race/ethnicity and other maternal characteristics. Median intake per day for nitrates, nitrites, total nitrites (nitrites + 5% nitrates), and nitrosamines was estimated at 40.48 mg, 1.53 mg, 3.69 mg, and 0.472 microg respectively. With the lowest quartile of intake as the referent category and controlling for daily caloric intake, factors predicting intake of these compounds included maternal race/ethnicity, education, body mass index, household income, area of residence, folate intake, and percent of daily calories from dietary fat. Non-Hispanic White participants were less likely to consume nitrates, nitrites, and total nitrites per day, but more likely to consume dietary nitrosamines than other participants that participated in the NBDPS. Primary food sources of these compounds also varied by

  12. Elevated urinary levels of carcinogenic N-nitrosamines in patients with urinary tract infections measured by isotope dilution online SPE LC–MS/MS

    International Nuclear Information System (INIS)

    Hu, Chiung-Wen; Shih, Ying-Ming; Liu, Hung-Hsin; Chiang, Yi-Chen; Chen, Chih-Ming; Chao, Mu-Rong

    2016-01-01

    Highlights: • Nine N-nitrosamines in urine were quantified by LC–MS/MS. • N-nitrosodiphenylamine was firstly identified in human urine. • UTI patients had much higher N-nitrosamines concentrations than healthy subjects. • N-nitrosamines were dramatically decreased after antibiotic treatment. • NDMA was correlated with the pH, WBC esterase activity or nitrite in UTI patients. - Abstract: N-nitrosamines (NAms) are well-documented for their carcinogenic potential. Human exposure to NAms may arise from the daily environment and endogenous formation via the reaction of secondary amines with nitrites or from bacteria infection. We describe the use of isotope dilution online solid-phase extraction (SPE) LC–MS/MS to quantify nine NAms in human urine. This method was validated and further applied to healthy subjects and patients with urinary tract infection (UTI). N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosopyrrolidine (NPYR) and N-nitrosomorpholine (NMOR) were analyzed with an APCI source, while N-nitrosodiethylamine (NDEA), N-nitrosopiperidine (NPIP), N-nitrosodi-n-propylamine (NDPA), N-nitrosodibutylamine (NDBA) and N-nitrosodiphenylamine (NDPhA) were quantified with an ESI source, due to their effect on the sensitivity and chromatography. NDMA was the most abundant N-nitrosamine, while NDPhA was firstly identified in human. UTI patients had three to twelve-fold higher concentrations for NDMA, NPIP, NDEA, NMOR and NDBA in urine than healthy subjects, and the NAms were significantly decreased after antibiotics treatment. NDMA concentrations were also significantly correlated with the pH value, leukocyte esterase activity or nitrite in urines of UTI patients. Our findings by online SPE LC–MS/MS method evidenced that UTI patients experienced various NAms exposures, especially the potent carcinogen NDMA, which was likely induced by bacteria infection.

  13. Elevated urinary levels of carcinogenic N-nitrosamines in patients with urinary tract infections measured by isotope dilution online SPE LC–MS/MS

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Chiung-Wen [Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan (China); Shih, Ying-Ming [Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan (China); Division of Chest Medicine, Department of Internal Medicine, Changhua Christian Hospital, Changhua 500, Taiwan (China); Liu, Hung-Hsin [Department of Occupational Safety and Health, Chung Shan Medical University, Taichung 402, Taiwan (China); Chiang, Yi-Chen [Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan (China); School of Public Health, Xiamen University, Xiamen 361102, Fujian (China); Chen, Chih-Ming [Department of Occupational Safety and Health, Chung Shan Medical University, Taichung 402, Taiwan (China); Chao, Mu-Rong, E-mail: chaomurong@gmail.com [Department of Occupational Safety and Health, Chung Shan Medical University, Taichung 402, Taiwan (China); Department of Occupational Medicine, Chung Shan Medical University Hospital, Taichung 402, Taiwan (China)

    2016-06-05

    Highlights: • Nine N-nitrosamines in urine were quantified by LC–MS/MS. • N-nitrosodiphenylamine was firstly identified in human urine. • UTI patients had much higher N-nitrosamines concentrations than healthy subjects. • N-nitrosamines were dramatically decreased after antibiotic treatment. • NDMA was correlated with the pH, WBC esterase activity or nitrite in UTI patients. - Abstract: N-nitrosamines (NAms) are well-documented for their carcinogenic potential. Human exposure to NAms may arise from the daily environment and endogenous formation via the reaction of secondary amines with nitrites or from bacteria infection. We describe the use of isotope dilution online solid-phase extraction (SPE) LC–MS/MS to quantify nine NAms in human urine. This method was validated and further applied to healthy subjects and patients with urinary tract infection (UTI). N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosopyrrolidine (NPYR) and N-nitrosomorpholine (NMOR) were analyzed with an APCI source, while N-nitrosodiethylamine (NDEA), N-nitrosopiperidine (NPIP), N-nitrosodi-n-propylamine (NDPA), N-nitrosodibutylamine (NDBA) and N-nitrosodiphenylamine (NDPhA) were quantified with an ESI source, due to their effect on the sensitivity and chromatography. NDMA was the most abundant N-nitrosamine, while NDPhA was firstly identified in human. UTI patients had three to twelve-fold higher concentrations for NDMA, NPIP, NDEA, NMOR and NDBA in urine than healthy subjects, and the NAms were significantly decreased after antibiotics treatment. NDMA concentrations were also significantly correlated with the pH value, leukocyte esterase activity or nitrite in urines of UTI patients. Our findings by online SPE LC–MS/MS method evidenced that UTI patients experienced various NAms exposures, especially the potent carcinogen NDMA, which was likely induced by bacteria infection.

  14. Impact of Nitrification on the Formation of N-Nitrosamines and Halogenated Disinfection Byproducts within Distribution System Storage Facilities.

    Science.gov (United States)

    Zeng, Teng; Mitch, William A

    2016-03-15

    Distribution system storage facilities are a critical, yet often overlooked, component of the urban water infrastructure. This study showed elevated concentrations of N-nitrosodimethylamine (NDMA), total N-nitrosamines (TONO), regulated trihalomethanes (THMs) and haloacetic acids (HAAs), 1,1-dichloropropanone (1,1-DCP), trichloroacetaldehyde (TCAL), haloacetonitriles (HANs), and haloacetamides (HAMs) in waters with ongoing nitrification as compared to non-nitrifying waters in storage facilities within five different chloraminated drinking water distribution systems. The concentrations of NDMA, TONO, HANs, and HAMs in the nitrifying waters further increased upon application of simulated distribution system chloramination. The addition of a nitrifying biofilm sample collected from a nitrifying facility to its non-nitrifying influent water led to increases in N-nitrosamine and halogenated DBP formation, suggesting the release of precursors from nitrifying biofilms. Periodic treatment of two nitrifying facilities with breakpoint chlorination (BPC) temporarily suppressed nitrification and reduced precursor levels for N-nitrosamines, HANs, and HAMs, as reflected by lower concentrations of these DBPs measured after re-establishment of a chloramine residual within the facilities than prior to the BPC treatment. However, BPC promoted the formation of halogenated DBPs while a free chlorine residual was maintained. Strategies that minimize application of free chlorine while preventing nitrification are needed to control DBP precursor release in storage facilities.

  15. Fluorescence method for the determination of carcinogenic N-nitrosamines using N-(8-methoxy-5-quinolinesulfonyl)-aziridine

    International Nuclear Information System (INIS)

    Gracheva, I.N.; Kovel'man, I.R.; Pimenova, V.V.; Tochilkin, A.I.; Zhukova, G.F.

    1986-01-01

    The determination of carcinogenic N-nitrosamines (NA) in the environment and particularly in food products is, according to the authors, extremely important. The objective of the present work is the development of an easily accessible and highly sensitive method for the determination of NA. NA, isolated from food products, are denitrosated to their corresponding amines, which are then determined in the form of fluorescent derivatives by reaction with N-(8-methoxy-5-quinolinesulfonyl) aziridine. The validity of the results of NA analysis from food product was confirmed by gas-liquid chromatography using a thermoluminescent detector TEA-502. The limit of detection is 1x10 -10 mole of N-nitrosamine. The possibility of separating and determining the new fluorescent derivatives III(a-f) on silufol plates, which are easily obtained and widely used in analytical practice, was examined

  16. Elimination of N-nitrosamines and their precusors in some foods by 60Co γ-ray irradiation

    International Nuclear Information System (INIS)

    Hu Jifan; He Yingqiang; Song Puju

    1987-01-01

    N-Dimethylnitrosamine (NDMA) in some marine foods, such as dried shrimp, fish meal and salted fish, was drastically reduced by γ-ray irradiation with 60 Co. The shrimp contained 54.6 ppb NDMA, but only 29.3, 8.8, 11.4, and 1.9 ppb were detected after irradiation with doses of 5, 10, 15 and 20 kGy. The corresponding reduction was 46.3%, 83.9%, 79.1%, and 96.6%, respectively. Similar results were also obtained in other two kinds of foods. NDMA could be completely eliminated by the irradiation in aqueous solution, which was much more markable than that in food samples. The major irradiated products of NDMA were dimethylamine and nitrous acid, but no re-formation of nitrosamines took place. 60 Co irradiation also significantly decreased the content of nitrite in salted fish and in aqueous solution. No effect on nitrate could be observed

  17. Biochemical, Physiological and Transcriptomic Comparison between Burley and Flue-Cured Tobacco Seedlings in Relation to Carbohydrates and Nitrate Content

    Directory of Open Access Journals (Sweden)

    Yafei Li

    2017-12-01

    Full Text Available Burley tobacco is a genotype of chloroplast-deficient mutant with accumulates high levels of tobacco-specific nitrosamines (TSNAs which would induce malignant tumors in animals. Nitrate is a principle precursor of tobacco-specific nitrosamines. Nitrate content in burley tobacco was significantly higher than that in flue-cured tobacco. The present study investigated differences between the two tobacco types to explore the mechanisms of nitrate accumulation in burley tobacco. transcripts (3079 related to the nitrogen and carbon metabolism were observed. Expression of genes involved in carbon fixation, glucose and starch biosynthesis, nitrate translocation and assimilation were significantly low in burley tobacco than flue-cured tobacco. Being relative to flue-cured tobacco, burley tobacco was significantly lower at total nitrogen and carbohydrate content, nitrate reductase and glutamine synthetase activities, chlorophyll content and photosynthetic rate (Pn, but higher nitrate content. Burley tobacco required six-fold more nitrogen fertilizers than flue-cured tobacco, but both tobaccos had a similar leaf biomass. Reduced chlorophyll content and photosynthetic rate (Pn might result in low carbohydrate formation, and low capacity of nitrogen assimilation and translocation might lead to nitrate accumulation in burley tobacco.

  18. Elimination of N-nitrosamines and their precusors in some foods by /sup 60/Co. gamma. -ray irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Jifan, Hu; Yingqiang, He; Puju, Song

    1987-10-01

    N-Dimethylnitrosamine (NDMA) in some marine foods, such as dried shrimp, fish meal and salted fish, was drastically reduced by ..gamma..-ray irradiation with /sup 60/Co. The shrimp contained 54.6 ppb NDMA, but only 29.3, 8.8, 11.4, and 1.9 ppb were detected after irradiation with doses of 5, 10, 15 and 20 kGy. The corresponding reduction was 46.3%, 83.9%, 79.1%, and 96.6%, respectively. Similar results were also obtained in other two kinds of foods. NDMA could be completely eliminated by the irradiation in aqueous solution, which was much more markable than that in food samples. The major irradiated products of NDMA were dimethylamine and nitrous acid, but no re-formation of nitrosamines took place. /sup 60/Co irradiation also significantly decreased the content of nitrite in salted fish and in aqueous solution. No effect on nitrate could be observed.

  19. [Common competencies and contents in public health in graduate programs].

    Science.gov (United States)

    Davó, M A Carmen; Vives-Cases, Carmen; Benavides, Fernando García; Alvarez-Dardet, Carlos; Segura-Benedicto, Andreu; Icart, Teresa; Astasio, Paloma; Gil, Angel; Ortiz, M Del Rocío; García, Angel; Ronda, Elena; Bosch, Félix

    2011-01-01

    To identify fundamental public health competencies and contents in nursing, pharmacy, teaching, medicine, human nutrition and dietetics, optics and optometry, labor relations and human resources, and social work in graduate programs and to formulate proposals for their improvement. The workshop on Public health contents in graduate programs in the XXI Menorca Public Health School was organized as follows: eight groups were set up, coordinated by 37 Spanish university teachers participating in the workshop and selected through key informants and snowball techniques. Two studies on public health professional competencies and the participants' own graduate programs were used to discuss public health professional competencies and contents and establish recommendations to improve public health programs. Each group worked on a particular degree course and the results were shared in plenary. Professional competencies for the three essential public health functions were indentified in all the degrees, except teaching, optics and optometry, and social work. Some of the competencies included in degrees in nursing, teaching, human nutrition and dietetics, and social work were rewritten to highlight the role of each type of professional in public health functions. The groups agreed on the introductory topics (basic concepts and health determinants) and intervention strategies. Common competencies and contents were identified in graduate programs. Updating public health contents in graduate programs would help to define and promote the profile of public health professionals. Copyright © 2011 SESPAS. Published by Elsevier Espana. All rights reserved.

  20. Exposure to N-nitroso compounds in a population of high liver cancer regions in Thailand: volatile nitrosamine (VNA) levels in Thai food.

    Science.gov (United States)

    Mitacek, E J; Brunnemann, K D; Suttajit, M; Martin, N; Limsila, T; Ohshima, H; Caplan, L S

    1999-04-01

    The recent case-control studies in Thailand indicate that a high incidence of liver cancer in Thailand has not been associated with common risk factors such as hepatitis B infection, aflatoxin intake and alcohol consumption. While the infestation by the liver fluke Opisthorchis viverrini (OV) accounted for the high risk in north-east Thailand, there was no such exposure in the other regions of the country where the incidence of liver cancer is also high. Case-control studies suggest that exposure to exogenous and possibly endogenous nitrosamines in food or tobacco in betel nut and cigarettes may play a role in the development of hepatocellular carcinoma (HCC), while OV infestation and chemical interaction of nitrosamines may also be aetiological factors in the development of cholangiocarcinoma (CCA). Over 1800 samples of fresh and preserved food were systematically collected and tested between 1988 and 1996. All the food items identified by anthropological studies to be consumed frequently in four major regions of Thailand were analysed for volatile nitrosamines using gas chromatography combined with a thermal energy analyser. Relatively high levels of N-nitrosodimethylamine (NDMA), N-nitrosopiperidine (NPIP) and N-nitrosopyrrolidine (NPYR) were detected in fermented fish ("Plasalid"). NDMA was also detected at levels ranging from trace amounts to 66.5 microg/kg in several salted and dried fish ("Larb-pla" and "Pla-siu"). NDMA and NPYR were frequently detected in several vegetables, particularly fermented beans ("Tau-chiau") at levels ranging between 1 and 95.1 microg/kg and 0-146 microg/kg, respectively. The possible role of nitrosamines in Thai food in the aetiology of liver cancer (HCC, CCA) is discussed.

  1. Effects of Physalis peruviana L on Toxicity and Lung Cancer Induction by Nicotine Derived Nitrosamine Ketone in Rats.

    Science.gov (United States)

    El-Kenawy, Ayman El-Meghawry; Elshama, Said Said; Osman, Hosam-Eldin Hussein

    2015-01-01

    Nicotine-derived nitrosamine ketone (NNK) is considered a key tobacco smoke carcinogen inducing lung tumors. Physalis peruviana L (harankash) is considered one plant with marked health benefits. This study aimed to evaluate Physalis peruviana L effect on the toxic effect of NNK induced lung cancer in the rats by using pulmonary histopathological, immunohistochemical and DNA flow cytometric analyses. Sixty adult male rats were divided into four groups, each consisting of fifteen animals. The first group received saline, the second received two successive toxic doses of NNK only while the third received two successive toxic doses of NNK with a single daily dose of Physalis peruviana L. The fourth group received a single daily dose of Physalis peruviana L only. Toxic doses of NNK induced hyperplasia and adenocarcinoma in the lung and positive immunoreactivity for Ki-67 and p53 staining with disturbance of the lung DNA content. Administration of Physalis peruviana L with NNK led to a mild pulmonary hyperplasia and weak expression of Ki-67 and p53 with an improvement in the lung DNA content. Physalis peruviana L may protect against NNK induced lung carcinogenesis due to its antioxidant and anti-proliferative effects.

  2. Effect of irradiation on the prevulcanized latex/low nitrosamines latex blends

    Energy Technology Data Exchange (ETDEWEB)

    Ibrahim, Pairu; Zin, Wan Manshol Wan [Malaysian Nuclear Agency, 43000 kajang, Selangor (Malaysia); Daik, Rusli [Faculty of Science and Technology, Universiti Kebangsaan Malaysia,43600 bangi, Selangor (Malaysia)

    2015-09-25

    Radiation Prevulcanized Natural Rubber Latex (RVNRL) was blended with Low Nitrosamines Latex (LNL) at different composition ratio. Methyl Metachrylate (MMA) was added for grafting onto the blended latex. Blended latex was subjected to gamma irradiation at various doses up to 8kGy. The mechanical properties and FTIR analysis were investigated as a function of the blended composition and irradiation dose. It was found that blending at specific ratio and gamma irradiation at specific dose led to significant improvement on the properties of the latex. The optimum mechanical properties was attained at a total blending ratio of 70% RVNRL and 30% of LNL.

  3. Application of ultraviolet, ozone, and advanced oxidation treatments to washwaters to destroy nitrosamines, nitramines, amines, and aldehydes formed during amine-based carbon capture.

    Science.gov (United States)

    Shah, Amisha D; Dai, Ning; Mitch, William A

    2013-03-19

    Although amine-based CO(2) absorption is a leading contender for full-scale postcombustion CO(2) capture at power plants, concerns have been raised about the potential release of carcinogenic N-nitrosamines and N-nitramines formed by reaction of exhaust gas NO(x) with the amines. Experiments with a laboratory-scale pilot unit suggested that washwater units meant to scrub contaminants from absorber unit exhaust could potentially serve as a source of N-nitrosamines via reactions of residual NO(x) with amines accumulating in the washwater. Dosage requirements for the continuous treatment of the washwater recycle line with ultraviolet (UV) light for destruction of N-nitrosamines and N-nitramines, and with ozone or hydroxyl radical-based advanced oxidation processes (AOPs) for destruction of amines and aldehydes, were evaluated. Although amine destruction. Ozone achieved 90% amine removal in washwaters at 5-12 molar excess of ozone, indicating transferred dosage levels of ∼100 mg/L for 90% removal in a first-stage washwater unit, but likely only ∼10 mg/L if applied to a second-stage washwater. Accurate dosage and cost estimates would require pilot testing to capture synergies between UV and ozone treatments.

  4. Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines

    NARCIS (Netherlands)

    van Maanen, J.M.S.; Welle, I.J.; Hageman, G.J.; Dallinga, J.W.; Mertens, P.L.; Kleinjans, J.C.S.

    1996-01-01

    Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines. van Maanen JM, Welle IJ, Hageman G, Dallinga JW, Mertens PL, Kleinjans JC. Department of Health Risk Analysis and Toxicology, University of Limburg,

  5. [Public health competencies and contents in Spanish undergraduate medical degrees].

    Science.gov (United States)

    Davó-Blanes, M Carmen; Vives-Cases, Carmen; Barrio-Fernández, José Luis; Porta, Miquel; Benavides, Fernando G; de Miguel, Ángel Gil

    2016-01-01

    To reach a consensus among public health faculty from various Spanish universities about the core public health competencies that should be integrated into undergraduate medical degrees. The 2nd Forum of University Teachers was held at the Rey Juan Carlos University (Madrid, 11-12 December 2014). Twenty-four university professors and lecturers from 19 Spanish universities imparting medical degrees participated in the forum. They were distributed in three working groups during three working sessions. In the first session, they were asked to identify and classify core public health competencies for medical degrees. In the second, they were asked to propose public health contents for the identified competencies. In the third session, the participants organized these contents in thematic blocks. The results were discussed in distinct plenary sessions. The highest number of core competencies was identified in the activities related to the public health functions «Assessment of the population's health needs» and «Developing health policies». The final programme included basic contents organised into five units: Concept of health, public health and its determinants; Epidemiology and health research; Determinants and health problems; Strategies, interventions and policies; and health systems, clinical and healthcare management. The public health core competencies and contents identified in this Forum may be considered as a starting point to improve and update public health training programmes for future medical professionals. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  6. Dietary Nitrates, Nitrites, and Nitrosamines Intake and the Risk of Gastric Cancer: A Meta-Analysis

    OpenAIRE

    Peng Song; Lei Wu; Wenxian Guan

    2015-01-01

    The potential associations between dietary consumption of nitrates, nitrites, and nitrosamines and gastric cancer risk have been investigated by several studies, but yielded inconclusive results. We conducted a meta-analysis to provide a quantitative assessment of their relationships. Relevant articles were identified by a systematic literature searching of PubMed and Embase databases prior to August 2015. Random-effects models were employed to pool the relative risks. A total of 22 articles ...

  7. Determination of nitrosamines and caffeine metabolites in wastewaters using gas chromatography mass spectrometry and ionic liquid stationary phases.

    Science.gov (United States)

    Reyes-Contreras, Carolina; Domínguez, Carmen; Bayona, Josep M

    2012-10-26

    Recently, the interest to assess the environmental and human health effects of a wide group of emerging contaminants is growing worldwide. However, one of the main problems associated to their exposure is their determination in environmental matrices. It is hindered by the high polarity of most of these analytes, the poor selectivity obtained with low polarity stationary phases and the high background obtained with polar columns commonly used in GC-MS. Accordingly, this study examines the suitability of ionic liquid (IL) (e.g. SLB-IL59, SLB-IL61, SLB-IL82 and SLB-IL111) as stationary phases for GC-MS and their application to the determination of nitrosamines and caffeine metabolites in wastewater samples. Different chromatographic conditions were evaluated and results discussed in terms of resolution and peak symmetry. The SLB-IL111 column enabled the baseline separation and quantification of 7 nitrosamines in a shorter analysis time compared with cyanopropylphenyl polysiloxane commonly used. On the other hand, the SLB-IL59 column provided the best results for caffeine metabolites. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. Analysis of nitrosamines in water by automated SPE and isotope dilution GC/HRMS Occurrence in the different steps of a drinking water treatment plant, and in chlorinated samples from a reservoir and a sewage treatment plant effluent.

    Science.gov (United States)

    Planas, Carles; Palacios, Oscar; Ventura, Francesc; Rivera, Josep; Caixach, Josep

    2008-08-15

    A method based on automated solid-phase extraction (SPE) and isotope dilution gas chromatography/high resolution mass spectrometry (GC/HRMS) has been developed for the analysis of nine nitrosamines in water samples. The combination of automated SPE and GC/HRMS for the analysis of nitrosamines has not been reported previously. The method shows as advantages the selectivity and sensitivity of GC/HRMS analysis and the high efficiency of automated SPE with coconut charcoal EPA 521 cartridges. Low method detection limits (MDLs) were achieved, along with a greater facility of the procedure and less dependence on the operator with regard to the methods based on manual SPE. Quality requirements for isotope dilution-based methods were accomplished for most analysed nitrosamines, regarding to trueness (80-120%), method precision (water samples (16 samples from a drinking water treatment plant {DWTP}, 2 chlorinated samples from a sewage treatment plant {STP} effluent, and 1 chlorinated sample from a reservoir) were analysed. Concentrations of nitrosamines in the STP effluent were 309.4 and 730.2 ng/L, being higher when higher doses of chlorine were applied. N-Nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) were the main compounds identified in the STP effluent, and NDEA was detected above 200 ng/L, regulatory level for NDMA in effluents stated in Ontario (Canada). Lower concentrations of nitrosamines were found in the reservoir (20.3 ng/L) and in the DWTP samples (n.d. -28.6 ng/L). NDMA and NDEA were respectively found in the reservoir and in treated and highly chlorinated DWTP samples at concentrations above 10 ng/L (guide value established in different countries). The highest concentrations of nitrosamines were found after chlorination and ozonation processes (ozonated, treated and highly chlorinated water) in DWTP samples.

  9. Analysis of nitrosamines in cooked bacon by QuEChERS sample preparation and gas chromatography – tandem mass spectrometry with backflushing

    Science.gov (United States)

    Nitrites are added as a preservative to a variety of cured meats, including bacon, to kill bacteria, extend shelf-life, and improve quality. During cooking, nitrites in the meat can be converted to carcinogenic nitrosamines (NAs), the formation of which are mitigated by the addition of anti-oxidant...

  10. [Public health competencies and contents in pharmacy degree programs in Spanish universities].

    Science.gov (United States)

    Lumbreras, Blanca; Davó-Blanes, María Carmen; Vives-Cases, Carmen; Bosch, Félix

    2015-01-01

    To identify public health core competencies and contents in pharmacy degrees at a meeting of public health lecturers in pharmacy degrees from various public and private universities. The first Meeting of the Forum of University Teaching Staff in Pharmacy Degrees was held at the Faculty of Medicine in the Complutense University, Madrid, Spain on the 19(th) and 20(th) of November 2013. The meeting was attended by 17 lecturers. Participants brought their own teaching programs and were given two previous studies on public health competencies for analysis of public health contents and competencies in pharmacy degrees. Working groups were formed and the results were shared. The highest number of core competencies was identified in the following functions: "Assessment of the population's health needs" and "Developing health policies". The final program included basic contents organized into 8 units: Concept of Public Health, Demography, Epidemiological Method, Environment and Health, Food Safety, Epidemiology of Major Health Problems, Health Promotion and Education, and Health Planning and Management. Representation of almost all the Spanish Pharmacy Faculties and the consensus reached in the description of competences and program contents will greatly improve the quality of teaching in this area. Copyright © 2014 SESPAS. Published by Elsevier Espana. All rights reserved.

  11. The Gap between Professional and Research Agenda: A Content Analysis of "Public Relations Journal" and "Public Relations Review."

    Science.gov (United States)

    Broom, Glen M.; And Others

    A content analysis compared the professional and research agendas of "Public Relations Journal" and "Public Relations Review" for the years 1975-81. A sample of 121 articles from the former and 111 articles from the latter were analyzed, and the content of each was assigned to one of 10 categories related to the context,…

  12. [Public health competencies and contents in Spanish university degree programmes of Veterinary Medicine].

    Science.gov (United States)

    Davó-Blanes, María Del Carmen; Vives-Cases, Carmen; Huerta, Belén

    2017-04-19

    To reach a consensus among public health faculty from various Spanish universities about the core public health competencies that should be integrated into the Veterinary Medicine degree training. The 3rd Forum of University Professors of Public Health was held at the School of Veterinary Medicine of the University of Cordoba (12-13 January 2016). Forty-two university professors and lecturers from nine Spanish universities with veterinary degrees participated in the forum. They were divided into five working groups during three working sessions to identify and classify core public health competencies for the Veterinary Medicine degree, propose public health contents for the identified competencies and organize such contents in thematic blocks. The results were discussed in different plenary sessions. The highest number of core competencies was identified in the activities related to the following public health functions: «Assessment of the population's health needs» and «Developing health policies». The final programme included basic contents organized into five units: 1) Fundamentals of public health; 2) Study and research in public health; 3) Production, animal health and environment; 4) Food security; and 5) Health education. The public health core competencies and contents identified in this Forum may be considered as a starting point to update public health training programmes for future veterinary professionals. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  13. Determinants of disinfectant pretreatment efficacy for nitrosamine control in chloraminated drinking water.

    Science.gov (United States)

    McCurry, Daniel L; Krasner, Stuart W; von Gunten, Urs; Mitch, William A

    2015-11-01

    Utilities using chloramines need strategies to mitigate nitrosamine formation to meet potential future nitrosamine regulations. The ability to reduce NDMA formation under typical post-chloramination conditions of pretreatment with ultraviolet light from a low pressure mercury lamp (LPUV), free chlorine (HOCl), ozone (O3), and UV light from a medium pressure mercury lamp (MPUV) were compared at exposures relevant to drinking water treatment. The order of efficacy after application to waters impacted by upstream wastewater discharges was O3 > HOCl ≈ MPUV > LPUV. NDMA precursor abatement generally did not correlate well between oxidants, and waters exhibited different behaviors with respect to pH and temperature, suggesting a variety of source-dependent NDMA precursors. For wastewater-impacted waters, the observed pH dependence for precursor abatement suggested the important role of secondary or tertiary amine precursors. Although hydroxyl radicals did not appear to be important for NDMA precursor abatement during O3 or MPUV pretreatment, the efficacy of MPUV correlated strongly with dissolved organic carbon concentration (p = 0.01), suggesting alternative indirect photochemical pathways. The temperature dependences during pre- and post-disinfection indicated that NDMA formation is likely to increase during warm seasons for O3 pretreatment, decrease for HOCl pretreatment, and remain unchanged for MPUV treatment, although seasonal changes in source water quality may counteract the temperature effects. For two waters impacted by relatively high polyDADMAC coagulant doses, pretreatment with HOCl, O3, and MPUV increased NDMA formation during post-chloramination. For O3 pretreatment, hydroxyl radicals likely led to precursor formation from the polymer in the latter tests. MPUV treatment of polymer-impacted water increased subsequent NDMA formation through an indirect photochemical process. Many factors may mitigate the importance of this increased NDMA formation

  14. Occurence and dietary exposure of volatile and non-volatile N-Nitrosamines in processed meat products

    DEFF Research Database (Denmark)

    Herrmann, Susan Strange; Duedahl-Olesen, Lene; Granby, Kit

    Nitrite and nitrate have for many decades been used for preservation of meat. However, nitrite can react with secondary amines in meat to form N-Nitrosamines (NAs), many of which have been shown to be genotoxic1 . The use of nitrite therefore ought to be limited as much as possible. To maintain...... a high level of consumer protection Denmark obtains National low limits of the nitrite use in meat products. An estimation of the dietary exposure to volatile NAs (VNA) and non-volatile NAs (NVNA) is necessary when performing a risk assessment of the use of nitrite and nitrate for meat preservation....

  15. Role of Oxides of Nitrogen in Tobacco-Specific Nitrosamine Formation in Flue-Cured Tobacco

    Directory of Open Access Journals (Sweden)

    Nestor TB

    2014-12-01

    Full Text Available Tobacco is known to contain a class of nitrosamines known as tobacco-specific nitrosamines or TSNA. Nitrosation of naturally occurring tobacco alkaloids is commonly accepted as the mechanism of TSNA formation in tobacco. Because green and freshly harvested tobaccos are virtually free of TSNA, formation and accumulation of TSNA are generally considered to occur during the curing process. Most recent hypotheses have focused on microbial reduction of nitrate to nitrite and other oxides of nitrogen (NOcompounds that react with tobacco alkaloids to form TSNA during curing. This natural microbial process remains the prevalent hypothesis for TSNA formation in burley and other air-cured tobaccos. However, a different mechanism for the formation of TSNA in flue-cured tobacco, independent of microbial activity, is documented in this paper. It is common practice to flue-cure Virginia or blonde tobacco in bulk barns that incorporate forced air ventilation and temperature control. For the last thirty-five years, many modern bulk barns in North America generally have used liquid propane gas (LPG with direct-fired burners that exhaust combustion gases directly into the barn where the tobacco is exposed to those gases. Our studies indicate that LPG combustion by-products in the exhaust stream, namely NO, react with naturally occurring tobacco alkaloids to form TSNA. Heat exchange curing methods preclude exposure of the tobacco to combustion gases and by-products, thereby eliminating this significant source of TSNA formation, without degrading leaf quality or smoking character. Research findings from 1998 and 1999 are presented to demonstrate the role of NOgases in TSNA formation and the significance of direct-fired curing as a primary source of TSNA formation in flue-cured tobacco. Also, data from an extensive barn conversion program in 2000, which resulted in a 94% average reduction in TSNA levels in cured flue-cured leaf, are presented.

  16. Identification of N-nitrosamines in treated drinking water using nanoelectrospray ionization high-field asymmetric waveform ion mobility spectrometry with quadrupole time-of-flight mass spectrometry.

    Science.gov (United States)

    Zhao, Yuan Yuan; Liu, Xin; Boyd, Jessica M; Qin, Feng; Li, Jianjun; Li, Xing-Fang

    2009-01-01

    We report a nanoelectrospray ionization (nESI) with high-field asymmetric waveform ion mobility spectrometry (FAIMS) and tandem mass spectrometry (MS-MS) method for determination of small molecules of m/z 50 to 200 and its potential application in environmental analysis. Integration of nESI with FAIMS and MS-MS combines the advantages of these three techniques into one method. The nESI provides efficient sample introduction and ionization and allows for collection of multiple data from only microliters of samples. The FAIMS provides rapid separation, reduces or eliminates background interference, and improves the signal-to-noise ratio as much as 10-fold over nESI-MS-MS. The tandem quadrupole time-of-flight MS detection provides accurate mass and mass spectral measurements for structural identification. Characteristics of FAIMS compensation voltage (CV) spectra of seven nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosodiethylamine (NDEA), N-nitrosodi-n-propylamine (NDPA), N-nitrosodi-n-butylamine (NDBA), N-nitrosopiperidine (NPip), and N-nitrosopyrrolidine (NPyr), were analyzed. The optimal CV of the nitrosamines (at DV -4000 V) were: -1.6 V, NDBA; 2.6 V, NDPA; 6.6 V, NPip; 8.8 V, NDEA; 13.2 V, NPyr; 14.4 V, NMEA; and 19.4 V, NDMA. Fragmentation patterns of the seven nitrosamines in the nESI-FAIMS-MS-MS were also obtained. The specific CV and MS-MS spectra resulted in positive identification of NPyr and NPip in a treated water sample, demonstrating the potential application of this technique in environmental analysis.

  17. Effects of plant polyphenols and a-tocopherol on lipid oxidation, residual nitrites, biogenic amines, and N-nitrosamines formation during ripening and storage of dry-cured bacon

    Science.gov (United States)

    Effects of plant polyphenols (green tea polyphenols (GTP) and grape seed extract (GSE) and a-tocopherol on physicochemical parameters, lipid oxidation, residual nitrite, microbiological counts, biogenic amines, and N-nitrosamines were determined in bacons during dry-curing and storage. Results show ...

  18. Effectively incorporating selected multimedia content into medical publications.

    Science.gov (United States)

    Ziegler, Alexander; Mietchen, Daniel; Faber, Cornelius; von Hausen, Wolfram; Schöbel, Christoph; Sellerer, Markus; Ziegler, Andreas

    2011-02-17

    Until fairly recently, medical publications have been handicapped by being restricted to non-electronic formats, effectively preventing the dissemination of complex audiovisual and three-dimensional data. However, authors and readers could significantly profit from advances in electronic publishing that permit the inclusion of multimedia content directly into an article. For the first time, the de facto gold standard for scientific publishing, the portable document format (PDF), is used here as a platform to embed a video and an audio sequence of patient data into a publication. Fully interactive three-dimensional models of a face and a schematic representation of a human brain are also part of this publication. We discuss the potential of this approach and its impact on the communication of scientific medical data, particularly with regard to electronic and open access publications. Finally, we emphasise how medical teaching can benefit from this new tool and comment on the future of medical publishing.

  19. Pins and posters: Paradigms for content publication on situated displays.

    Science.gov (United States)

    José, Rui; Pinto, Hélder; Silva, Bruno; Melro, Ana

    2013-01-01

    Public-display systems are still far from being a medium for meeting people's diverse communication goals. Moving toward open displays will require publication paradigms that can overcome the challenges of meaningful engagement and enable users to fully understand and control the publication process. The metaphors of pins and posters have inspired two complementary paradigms for public displays. Researchers implemented these paradigms in the Instant Places system, which they deployed on 10 displays in diverse urban locations for six months. They collected user and system data regarding the users' practices. The findings improve the understanding of what might drive user-generated content in networks of urban displays. Such knowledge can inform the design of tools and procedures for situated publication in public displays.

  20. 40 CFR 141.205 - Content of the public notice.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Content of the public notice. 141.205 Section 141.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS..., especially those who may not have received this notice directly (for example, people in apartments, nursing...

  1. Effect of Sodium Nitrite and Sodium Nitrate on Botulinal Toxin Production and Nitrosamine Formation in Wieners

    Science.gov (United States)

    Hustad, Gerald O.; Cerveny, John G.; Trenk, Hugh; Deibel, Robert H.; Kautter, Donald A.; Fazio, Thomas; Johnston, Ralph W.; Kolari, Olaf E.

    1973-01-01

    Wieners were formulated and processed approximating commercial conditions as closely as possible. Twenty-four batches of product were made with the addition of six levels of sodium nitrite (0, 50, 100, 150, 200, and 300 μg/g), four levels of sodium nitrate (0, 50, 150, and 450 μg/g), and two levels of Clostridium botulinum (0 and 620 spores/g). After formulation, processing, and vacuum packaging, portions of each batch were incubated at 27 C or held for 21 days at 7 C followed by incubation at 27 C for 56 days. The latter storage condition approximated distribution of product through commercial channels and potential temperature abuse at the consumer level. Samples were analyzed for botulinal toxin, nitrite, and nitrate levels after 3, 7, 14, 21, 28, and 56 days of incubation. When nitrite was not added, toxic samples were detected after 14 days of incubation at 27 C. At the lowest level of nitrite added (50 μg/g), no toxic samples were observed until 56 days of incubation. Higher levels of nitrite completely inhibited toxin production throughout the incubation period. Nine uninoculated samples, representing various levels and combinations of nitrite and nitrate, were evaluated organoleptically. The flavor quality of wieners made with nitrite was judged significantly higher (P = 0.05) than of wieners made without nitrite. The nine samples were negative for 14 volatile nitrosamines at a sensitivity level of 10 ng/g. The results indicated that nitrite effectively inhibited botulinal toxin formation at commercially employed levels in wieners and that detectable quantities of nitrosamines were not produced during preparation and processing of the product for consumption. PMID:4580194

  2. 21 CFR 516.157 - Publication of the index and content of an index listing.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Publication of the index and content of an index... MINOR SPECIES Index of Legally Marketed Unapproved New Animal Drugs for Minor Species § 516.157 Publication of the index and content of an index listing. (a) FDA will make the list of indexed drugs...

  3. The ATLAS Public Web Pages: Online Management of HEP External Communication Content

    CERN Document Server

    Goldfarb, Steven; Phoboo, Abha Eli; Shaw, Kate

    2015-01-01

    The ATLAS Education and Outreach Group is in the process of migrating its public online content to a professionally designed set of web pages built on the Drupal content management system. Development of the front-end design passed through several key stages, including audience surveys, stakeholder interviews, usage analytics, and a series of fast design iterations, called sprints. Implementation of the web site involves application of the html design using Drupal templates, refined development iterations, and the overall population of the site with content. We present the design and development processes and share the lessons learned along the way, including the results of the data-driven discovery studies. We also demonstrate the advantages of selecting a back-end supported by content management, with a focus on workflow. Finally, we discuss usage of the new public web pages to implement outreach strategy through implementation of clearly presented themes, consistent audience targeting and messaging, and th...

  4. Neuroscience for Content Innovation on European Public Service Broadcasters

    Science.gov (United States)

    Crespo-Pereira, Verónica; Martínez-Fernández, Valentín-Alejandro; Campos-Freire, Francisco

    2017-01-01

    The new media landscape is characterized by the fragmentation and disaffection of the audience towards traditional television. Such a context requires innovative strategies to meet the needs of the public and connect with it. This article analyses the ability of Neuroscience to optimize the production of content adapted to audiences. For this…

  5. Factors affecting ultraviolet irradiation/hydrogen peroxide (UV/H2O2) degradation of mixed N-nitrosamines in water

    International Nuclear Information System (INIS)

    Zhou, Chao; Gao, Naiyun; Deng, Yang; Chu, Wenhai; Rong, Wenlei; Zhou, Shengdong

    2012-01-01

    Highlights: ► NAms with three-induced toxicity, as emerging DBPs, has caused a great public attention. ► No paper regards UV/H 2 O 2 oxidation of mixed NAms in an aquatic environment. ► The treatment effect is typically affected by a few factors in water. ► NPIP and NDPhA are the most readily and difficult to be degraded due to unique structure. ► All the NAms degradation exhibited a pseudo-first-order kinetics pattern. - Abstract: Disinfection by-products (DBPs) are a great challenge to our drinking water security. Particularly, nitrosamines (NAms), as emerging DBPs, are potently carcinogenic, mutagenic, and teratogenic, and have increasingly attained public attention. This study was to evaluate the performance of the NAms degradation by the ultraviolet (UV) irradiation (253.7 nm) in the presence of hydrogen peroxide (H 2 O 2 ). In the UV/H 2 O 2 system, hydroxyl radicals (OH·), a type of nonselective and powerful oxidant, was produced to attack the molecules of NAms. Factors affecting the treatment efficiency, including the H 2 O 2 dosage, initial NAms concentration, UV irradiation intensity, initial solution pH, and inorganic anions present in water, were evaluated. All the NAms degradation exhibited a pseudo-first-order kinetics pattern. Within 60 min, 0.1 mg/L of any NAms could be almost decomposed except NDPhA that required 120 min for complete removal, at 25 μmol/L H 2 O 2 and at initial pH 7. Results demonstrate that the UV/H 2 O 2 treatment is a viable option to control NAms in water.

  6. Determination of eight nitrosamines in water at the ng L-1 levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry

    International Nuclear Information System (INIS)

    Ripolles, Cristina; Pitarch, Elena; Sancho, Juan V.; Lopez, Francisco J.; Hernandez, Felix

    2011-01-01

    Highlights: · Eight N-nitrosamines in water by LC(APCI)MS/MS QqQ analysis. · Validation at two levels: 10 ng L -1 (LOQ) and 100 ng L -1 in drinking water. · Developed method applied to different types of water samples. · NDMA was the analyte more frequently detected and at the highest concentration levels. - Abstract: In this work, we have developed a sensitive method for detection and quantification of eight N-nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosomorpholine (NMor), N-nitrosomethylethylamine (NMEA), N-nitrosopirrolidine (NPyr), N-nitrosodiethylamine (NDEA), N-nitrosopiperidine (NPip), N-nitroso-n-dipropylamine (NDPA) and N-nitrosodi-n-butylamine (NDBA) in drinking water. The method is based on liquid chromatography coupled to tandem mass spectrometry, using atmospheric pressure chemical ionization (APCI) in positive mode with a triple quadrupole analyzer (QqQ). The simultaneous acquisition of two MS/MS transitions in selected reaction monitoring mode (SRM) for each compound, together with the evaluation of their relative intensity, allowed the simultaneous quantification and reliable identification in water at ppt levels. Empirical formula of the product ions selected was confirmed by UHPLC-(Q)TOF MS accurate mass measurements from reference standards. Prior to LC-MS/MS QqQ analysis, a preconcentration step by off-line SPE using coconut charcoal EPA 521 cartridges (by passing 500 mL of water sample) was necessary to improve the sensitivity and to meet regulation requirements. For accurate quantification, two isotope labelled nitrosamines (NDMA-d 6 and NDPA-d 14 ) were added as surrogate internal standards to the samples. The optimized method was validated at two concentration levels (10 and 100 ng L -1 ) in drinking water samples, obtaining satisfactory recoveries (between 90 and 120%) and precision (RSD -1 . The described methodology has been applied to different types of water samples: chlorinated from drinking water and wastewater treatment

  7. Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of U.S. Commercial Cigarettes

    Science.gov (United States)

    Edwards, Selvin H.; Rossiter, Lana M.; Taylor, Kenneth M.; Holman, Matthew R.; Zhang, Liqin; Ding, Yan S.; Watson, Clifford H.

    2016-01-01

    Tobacco-specific nitrosamines (TSNAs) are N-nitroso-derivatives of pyridine-alkaloids (e.g., nicotine) present in tobacco and cigarette smoke. Two TSNAs, N’-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), are included on the Food and Drug Administration’s list of harmful and potentially harmful constituents (HPHCs) in tobacco products and tobacco. The amounts of four TSNAs (NNK, NNN, N-nitrosoanabasine (NAB), and N’-nitrosoanatabine (NAT)) in the tobacco and mainstream smoke from 50 U.S. commercial cigarette brands were measured from November 15, 2011 to January 4, 2012 using a validated, HPLC-MS/MS method. Smoke samples were generated using the International Organization of Standardization (ISO) and Canadian Intense (CI) machine-smoking regimens. NNN and NAT were the most abundant TSNAs in tobacco filler and smoke across all cigarette brands whereas NNK and NAB were present in the least amounts. The average of the ratios for each TSNA in mainstream smoke to filler content is 29% by the CI smoking regimen and 13% for the ISO machine-smoking regimen. The reliability of each TSNA to predict total TSNA amounts in the filler and smoke was examined. NNN, NAT, and NAB have a moderate to high correlation (R2 = 0.61 – 0.98) and all three TSNAs individually predict total TSNAs with minimal difference between measured and predicted total TSNA amounts (error Tobacco weight and levels of TSNAs in filler influence TSNA levels in smoke from the CI machine-smoking regimen. In contrast, filter ventilation is a major determinant of levels of TSNAs in smoke by the ISO machine-smoking regimen. Comparative analysis demonstrates substantial variability in TSNA amounts in tobacco filler and mainstream smoke yields under ISO and CI machine smoking regimens among U.S. commercial cigarette brands. PMID:28001416

  8. Surveillance of smokeless tobacco nicotine, pH, moisture, and unprotonated nicotine content.

    Science.gov (United States)

    Richter, Patricia; Spierto, Francis W

    2003-12-01

    Smokeless tobacco is a complex chemical mixture, including not only the components of the tobacco leaf but also chemicals added during the manufacturing process. Smokeless tobacco contains the addictive chemical nicotine and more than 20 cancer-causing chemicals, including the potent tobacco-specific nitrosamines. The National Toxicology Program of the National Institutes of Health has concluded that oral use of smokeless tobacco is a human carcinogen. Therefore, smokeless tobacco is not a safe alternative to cigarettes. In fact, smokeless tobacco use begins primarily during early adolescence and can lead to nicotine dependence and increased risk of becoming a cigarette smoker. Under the Comprehensive Smokeless Tobacco Health Education Act of 1986 (15 U.S.C. 4401 et seq., Pub. L. 99-252), tobacco manufacturers report annually to the Centers for Disease Control and Prevention (CDC) on the total nicotine, unprotonated nicotine, pH, and moisture content of their smokeless tobacco products. This information is considered "trade secret," or confidential, in accordance with 5 U.S.C. 552(b)(4) and 18 U.S.C. 1905 and cannot be released to the public. In an effort to provide consumers and researchers with information on the nicotine content of smokeless tobacco, CDC arranged for the analysis of popular brands of smokeless tobacco. The results of this CDC study show that pH is a primary factor in the amount of nicotine that is in the most readily absorbable, unprotonated form. Furthermore, this study found that the brands of moist snuff smokeless tobacco with the largest amount of unprotonated nicotine also are the most frequently sold brands.

  9. Determination of eight nitrosamines in water at the ng L{sup -1} levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Ripolles, Cristina; Pitarch, Elena; Sancho, Juan V; Lopez, Francisco J [Research Institute for Pesticides and Water, University Jaume I, Avda. Sos Baynat, E-12071 Castellon (Spain); Hernandez, Felix [Research Institute for Pesticides and Water, University Jaume I, Avda. Sos Baynat, E-12071 Castellon (Spain)

    2011-09-19

    Highlights: {center_dot} Eight N-nitrosamines in water by LC(APCI)MS/MS QqQ analysis. {center_dot} Validation at two levels: 10 ng L{sup -1} (LOQ) and 100 ng L{sup -1} in drinking water. {center_dot} Developed method applied to different types of water samples. {center_dot} NDMA was the analyte more frequently detected and at the highest concentration levels. - Abstract: In this work, we have developed a sensitive method for detection and quantification of eight N-nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosomorpholine (NMor), N-nitrosomethylethylamine (NMEA), N-nitrosopirrolidine (NPyr), N-nitrosodiethylamine (NDEA), N-nitrosopiperidine (NPip), N-nitroso-n-dipropylamine (NDPA) and N-nitrosodi-n-butylamine (NDBA) in drinking water. The method is based on liquid chromatography coupled to tandem mass spectrometry, using atmospheric pressure chemical ionization (APCI) in positive mode with a triple quadrupole analyzer (QqQ). The simultaneous acquisition of two MS/MS transitions in selected reaction monitoring mode (SRM) for each compound, together with the evaluation of their relative intensity, allowed the simultaneous quantification and reliable identification in water at ppt levels. Empirical formula of the product ions selected was confirmed by UHPLC-(Q)TOF MS accurate mass measurements from reference standards. Prior to LC-MS/MS QqQ analysis, a preconcentration step by off-line SPE using coconut charcoal EPA 521 cartridges (by passing 500 mL of water sample) was necessary to improve the sensitivity and to meet regulation requirements. For accurate quantification, two isotope labelled nitrosamines (NDMA-d{sub 6} and NDPA-d{sub 14}) were added as surrogate internal standards to the samples. The optimized method was validated at two concentration levels (10 and 100 ng L{sup -1}) in drinking water samples, obtaining satisfactory recoveries (between 90 and 120%) and precision (RSD < 20%). Limits of detection were found to be in the range of 1-8 ng L{sup -1

  10. Implementing the Institute of Medicine’s Recommended Curriculum Content in Schools of Public Health: A Baseline Assessment

    Science.gov (United States)

    Shortell, Stephen M.; Weist, Elizabeth M.; Sow, Mah-Sere Keita; Foster, Allison; Tahir, Ramika

    2004-01-01

    In September 2003, the Association of Schools of Public Health administered an online survey to representatives of all 33 accredited US schools of public health. The survey assessed the extent to which the schools were offering curriculum content in the 8 areas recommended by the Institute of Medicine: communication, community-based participatory research, cultural competence, ethics, genomics, global health, informatics, and law/policy. Findings indicated that, for the most part, schools of public health are offering content in these areas through many approaches and have incorporated various aspects of a broad-based ecological approach to public health education and training. The findings also suggested the possible need for greater content in genomics, informatics, community-based participatory research, and cultural competence. PMID:15451728

  11. Synthesis of (plus or minus) [5-3H] N'-Nitrosoanatabine, a tobacco-specific nitrosamine

    International Nuclear Information System (INIS)

    Desai, Dhimant; Lin, Guoying; Morimoto, Hiromi; Williams, Philip G.; El-Bayoumy, Karam; Amin, Shantu

    2002-01-01

    Tobacco-specific N'-nitrosamines (TSNA) are a unique class of systemic organ-specific carcinogens. The TSNA are formed by N-nitrosation of nicotine and of the minor tobacco alkaloids after harvesting of tobacco and during smoking. The N-nitrosation of anatabine leads to N'-nitrosoanatabine (NAT; 1-nitroso-1,2,3,4-tetrahydro-2,3'-bipyridyl) which requires in-depth assays in laboratory animals other than the rat. Furthermore, delineation of its tissue distribution and metabolism is needed for structure:activity comparisons with other TSNA and for the assessment of potential human risk from this TSNA. We have, therefore, synthesized (+)[5-3H]NAT. 5-Bromo-3-pyridine-carboxaldehyde was condensed with ethyl carbamate prior to Diels-Alder reaction with 1,4-butadiene to give the racemic anatabine ring system. Hydrolysis followed by reduction with LiAlT4 and nitrosation, led to (+)[5-3H]NAT (60 percent yield, specific activity 266 mCi/mmol, radiochemical purity of >99 percent)

  12. METHOD DEVELOPMENT FOR THE ANALYSIS OF N-NITROSODIMETHYLAMINE AND OTHER N-NITROSAMINES IN DRINKING WATER AT LOW NANOGRAM/LITER CONCENTRATIONS USING SOLID PHASE EXTRACTION AND GAS CHROMATOGRAPHY WITH CHEMICAL IONIZATION TANDEM MASS SPECTROMETRY

    Science.gov (United States)

    N-Nitrosodimethylamine (NDMA) is a probable human carcinogen that has been identified as a drinking water contaminant of concern. United States Environmental Protection Agency (USEPA) Method 521 has been developed for the analysis of NDMA and six additional N-nitrosamines in dri...

  13. Metabolismus des tabakspezifischen Nitrosamins N'-Nitrosonornicotin in Gewebeschnitten von Mäusen, Ratten und Menschen sowie Möglichkeiten der Hemmung durch Nicotin, Cotinin und Phenethylisothiocyanat

    OpenAIRE

    Lassnack, Bettina

    2005-01-01

    Das Ziel dieser Arbeit war es, speziesspezifische Unterschiede in der Metabolisierung des tabakspezifischen Nitrosamins N'-Nitrosonornicotin (NNN) in den Organen Lunge und Leber von Mäusen, Ratten und Mensch zu untersuchen. Gewebeschnitte von Lunge und Leber der Maus, Ratte und des Menschen wurden unter identischen Versuchsbedingungen mit [5-3H]-NNN sechs Stunden inkubiert. Es kamen je 8 Konzentrationen von 0,001 bis 1,2 µM zum Einsatz. Bei Maus und Ratte wurden pro Konzentration die Schnitte...

  14. Genotoxicity study on nicotine and nicotine-derived nitrosamine by accelerator mass spectrometry

    International Nuclear Information System (INIS)

    Li, X.S.; Wang, H.F.; Shi, J.Y.; Wang, X.Y.; Liu, Y.F.; Li, K.; Lu, X.Y.; Wang, J.J.; Liu, K.X.; Guo, Z.Y.

    1997-01-01

    The authors have studied DNA adduction with 14 C-labelled nicotine and nicotine-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), by accelerator mass spectrometry (AMS) in mouse liver at doses equivalent to low-level exposure of humans. The dose ranges of nicotine and NNK administered were from 0.4 μg to 4.0 x 10 2 μg·kg -1 , and from 0.1 μg to 2.0 x 10 4 μg·kg -1 , respectively. In the exposure of mice to either nicotine or NNK, the number of DNA adducts increased linearly with increasing dose. The detection limit of DNA adducts was 1 adduct per 10 11 nucleotide molecules. This limit is 1-4 orders of magnitude lower than that of other techniques used for quantification of DNA adducts. The results of the animal experiments enabled us to speculate that nicotine is a potential carcinogen. According to the procedure for 14 C-labelled-NNK synthesis, the authors discuss the ultimate chemical speciation of NNK bound to DNA. From the animal tests the authors derived a directly perceivable relation between tobacco consumption and DNA adduction as the carcinogenic risk assessment

  15. Capturing public opinion on public health topics: a comparison of experiences from a systematic review, focus group study, and analysis of online, user-generated content

    Directory of Open Access Journals (Sweden)

    Emma Louise Giles

    2015-08-01

    Full Text Available BackgroundCapturing public opinion towards public health topics is important to ensure that services, policy and research are aligned with the beliefs and priorities of the general public. A number of approaches can be used to capture public opinion. MethodsWe are conducting a programme of work on the effectiveness and acceptability of health promoting financial incentive interventions. We have captured public opinion on financial incentive interventions using three methods: a systematic review, focus group study, and analysis of online user-generated comments to news media reports. In this short, editorial-style, piece we compare and contrast our experiences with these three methods.ResultsEach of these methods had their advantages and disadvantages. Advantages include tailoring of the research question for systematic reviews, probing of answers during focus groups, and the ability to aggregate a large data set using online user-generated content. However, disadvantages include needing to update systematic reviews, participants conforming to a dominant perspective in focus groups, and being unable to collect respondent characteristics during analysis of user-generated online content. That said, analysis of user-generated online content offers additional time and resource advantages, and we found it elicited similar findings to those obtained via more traditional methods, such as systematic reviews and focus groups. ConclusionsA number of methods for capturing public opinions on public health topics are available. Public health researchers, policy makers and practitioners should choose methods appropriate to their aims. Analysis user-generated online content, especially in the context of news media reports, may be a quicker and cheaper alternative to more traditional methods, without compromising on the breadth of opinions captured.

  16. Capturing Public Opinion on Public Health Topics: A Comparison of Experiences from a Systematic Review, Focus Group Study, and Analysis of Online, User-Generated Content.

    Science.gov (United States)

    Giles, Emma Louise; Adams, Jean M

    2015-01-01

    Capturing public opinion toward public health topics is important to ensure that services, policy, and research are aligned with the beliefs and priorities of the general public. A number of approaches can be used to capture public opinion. We are conducting a program of work on the effectiveness and acceptability of health promoting financial incentive interventions. We have captured public opinion on financial incentive interventions using three methods: a systematic review, focus group study, and analysis of online user-generated comments to news media reports. In this short editorial-style piece, we compare and contrast our experiences with these three methods. Each of these methods had their advantages and disadvantages. Advantages include tailoring of the research question for systematic reviews, probing of answers during focus groups, and the ability to aggregate a large data set using online user-generated content. However, disadvantages include needing to update systematic reviews, participants conforming to a dominant perspective in focus groups, and being unable to collect respondent characteristics during analysis of user-generated online content. That said, analysis of user-generated online content offers additional time and resource advantages, and we found it elicited similar findings to those obtained via more traditional methods, such as systematic reviews and focus groups. A number of methods for capturing public opinions on public health topics are available. Public health researchers, policy makers, and practitioners should choose methods appropriate to their aims. Analysis of user-generated online content, especially in the context of news media reports, may be a quicker and cheaper alternative to more traditional methods, without compromising on the breadth of opinions captured.

  17. Nitrate, sulphate and chloride contents in public drinking water supplies in Sicily, Italy.

    Science.gov (United States)

    D'Alessandro, Walter; Bellomo, Sergio; Parello, Francesco; Bonfanti, Pietro; Brusca, Lorenzo; Longo, Manfredi; Maugeri, Roberto

    2012-05-01

    Water samples collected from public drinking water supplies in Sicily were analysed for electric conductivity and for their chloride, sulphate and nitrate contents. The samples were collected as uniformly as possible from throughout the Sicilian territory, with an average sampling density of about one sample for every 7,600 inhabitants. Chloride contents that ranged from 5.53 to 1,302 mg/l were correlated strongly with electric conductivity, a parameter used as a proxy for water salinity. The highest values are attributable to seawater contamination along the coasts of the island. High chloride and sulphate values attributable to evaporitic rock dissolution were found in the central part of Sicily. The nitrate concentrations ranged from 0.05 to 296 mg/l, with 31 samples (4.7% of the total) exceeding the maximum admissible concentration of 50 mg/l. Anomalous samples always came from areas of intensive agricultural usage, indicating a clear anthropogenic origin. The same parameters were also measured in bottled water sold in Sicily, and they all were within the ranges for public drinking water supplies. The calculated mean nitrate intake from consuming public water supplies (16.1 mg/l) did not differ significantly from that of bottled water (15.2 mg/l). Although the quality of public water supplies needs to be improved by eliminating those that do not comply with the current drinking water limits, at present it does not justify the high consumption of bottled water (at least for nitrate contents).

  18. [Public health competencies and contents in Spanish university degree programs of physical therapy, occupational therapy, environmental science, dentistry and veterinary science].

    Science.gov (United States)

    Davó-Blanes, M Carmen; Vives-Cases, Carmen; Alvarez-Dardet, Carlos; Segura-Benedicto A, Andreu; Bosch Llonch, Fèlix; G Benavides, Fernando

    2014-01-01

    To identify the basic competencies and contents related to public health to be included in degree programs according to the perspective of lecturers from various Spanish universities. In the context of the Second Workshop on Public Health Contents in Degree Programs (Mahon, 19 to 20 September 2012), 20 lecturers from different Spanish universities were distributed in five working groups. The lecturers had been selected from the instructional guides on public health and epidemiology published on the web sites of the Rectors' Conference of Spanish Universities. Each group worked on a degree program and the results were discussed in plenary sessions. The activities and competencies related to the three basic functions of public health were identified in all degree programs. Most of the professional competencies identified were related to the function of «assessment of population health needs». The contents proposed by the working groups related to epidemiology, basic concepts in public health, public health intervention, health management, and health policy. The main common topics among the degrees concerned the first three contents. Public health professional competencies and contents were identified in the degree programs examined. These results may serve as a starting point for a more detailed review of public health programs across degree levels and the search for a consensus on the common content that should be included in each of them. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

  19. Caring for Our Future: The Content of Prenatal Care. A Report of the Public Health Service Expert Panel on the Content of Prenatal Care.

    Science.gov (United States)

    National Institutes of Health (DHHS), Bethesda, MD.

    This report describes effective approaches for enhancing maternal, infant, and family outcomes based on the scientific and systematic assessment of the content of prenatal care conducted by the Public Health Service's Expert Panel on the Content of Prenatal Care. The range of risks, both medical and psychosocial, that the prenatal care provider…

  20. Microporous Carbon Spheres Solid Phase Membrane Tip Extraction for the Analysis of Nitrosamines in Water Samples

    International Nuclear Information System (INIS)

    Mohammed Salisu Musa; Wan Aini Wan Ibrahim

    2015-01-01

    A simple solid phase membrane tip extraction (SPMTE) utilizing microporous carbon spheres (MCS) was developed for the analysis of nitrosamines in aqueous samples. The method termed MCS-SPMTE was optimized for various important extraction parameters namely conditioning organic solvent, extraction time, effects of salt addition and pH change, desorption time, desorption solvent and sample volume. Under the optimized conditions, the method indicated good linearity in the range of 10-100 μg/ L with coefficients of determination, r 2 ≥0.9984. The method also demonstrated good reproducibility with % RSDs values ranging from 2.2 - 8.9 (n = 3). Limit of detection (LOD) and limit of quantification (LOQ) for the method ranged from 3.2 - 4.8 μg/ L and 10.9 - 15.9 μg/L respectively. Recoveries for both tap-water and lake water samples spiked at 10 μg/L were in the range of 83.2 - 107.5 %. (author)

  1. Synthesis of (plus or minus) [5-{sup 3}H] N'-Nitrosoanatabine, a tobacco-specific nitrosamine

    Energy Technology Data Exchange (ETDEWEB)

    Desai, Dhimant; Lin, Guoying; Morimoto, Hiromi; Williams, Philip G.; El-Bayoumy, Karam; Amin, Shantu

    2002-06-14

    Tobacco-specific N'-nitrosamines (TSNA) are a unique class of systemic organ-specific carcinogens. The TSNA are formed by N-nitrosation of nicotine and of the minor tobacco alkaloids after harvesting of tobacco and during smoking. The N-nitrosation of anatabine leads to N'-nitrosoanatabine (NAT; 1-nitroso-1,2,3,4-tetrahydro-2,3'-bipyridyl) which requires in-depth assays in laboratory animals other than the rat. Furthermore, delineation of its tissue distribution and metabolism is needed for structure:activity comparisons with other TSNA and for the assessment of potential human risk from this TSNA. We have, therefore, synthesized (+)[5-3H]NAT. 5-Bromo-3-pyridine-carboxaldehyde was condensed with ethyl carbamate prior to Diels-Alder reaction with 1,4-butadiene to give the racemic anatabine ring system. Hydrolysis followed by reduction with LiAlT4 and nitrosation, led to (+)[5-3H]NAT (60 percent yield, specific activity 266 mCi/mmol, radiochemical purity of >99 percent).

  2. Protective single/combined treatment with betel leaf and turmeric against methyl (acetoxymethyl) nitrosamine-induced hamster oral carcinogenesis.

    Science.gov (United States)

    Azuine, M A; Bhide, S V

    1992-05-28

    The inhibitory effect of oral administration of betel-leaf extract (BLE) and 2 of its constituents, beta-carotene and alpha-tocopherol, as single agents or in combination with dietary turmeric on methyl(acetoxymethyl)nitrosamine (DMN-OAC)-induced oral carcinogenesis in Syrian hamsters was studied. DMN-OAC was administered twice monthly for 6 months. The chemopreventive effect of BLE or its constituents with turmeric was determined by comparing tumor incidence observed in treated groups with that seen in control animals. The apparent site-specific chemopreventive effect of BLE or its constituents was demonstrated by inhibition of tumor incidence, reduction of tumor burden, extension of the tumor latency period and regression of established, frank tumors. The inhibitory effect of BLE or its constituents combined with turmeric was higher than that of the individual constituents. The study suggests that BLE could be developed as a potential chemopreventive agent for human oral cancer.

  3. A high efficient nanostructured filter based on functionalized carbon nanotube to reduce the tobacco-specific nitrosamines, NNK

    Science.gov (United States)

    Yoosefian, Mehdi

    2018-03-01

    Filtration efficiency of Pd and Ni loaded single-walled carbon nanotubes via the applicability of the adsorption process for the removal NNK, the tobacco-specific nitrosamines, from tobacco smoke were investigated using first-principles calculations. The thermal and mechanical stability of designed nanostructured filter could allow them to compete with typical commercially used. It is expected that the removal efficiency of the proposed nanostructured filter could also provide a promising adsorbent candidate in removing the environmental pollutant. The suggested separation mechanism in this study was discussed with frontier molecular orbital theory, natural bond orbital (NBO) analyses and the density of states in the density functional theory framework. Finally, by the Bader theory of atoms in molecules (AIM), the topological properties of the electron density contributions for intermolecular and intramolecular interactions has been analyzed. Calculations show that the transition metal-loaded SWCNT exhibit strong affinity toward the NNK molecules.

  4. It is time to regulate carcinogenic tobacco-specific nitrosamines in cigarette tobacco

    Science.gov (United States)

    Hecht, Stephen S.

    2014-01-01

    The Family Smoking Prevention and Tobacco Control Act gives the Food and Drug Administration power to regulate tobacco products. This commentary calls for immediate regulation of the carcinogenic tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N’-nitrosonornicotine (NNN) in cigarette tobacco as a logical path to cancer prevention. NNK and NNN, powerful carcinogens in laboratory animals, have been evaluated as “carcinogenic to humans” by the International Agency for Research on Cancer. NNK and NNN are present in the tobacco of virtually all marketed cigarettes; levels in cigarette smoke are directly proportional to the amounts in tobacco. The NNK metabolite NNAL, itself a strong carcinogen, is present in the urine of smokers and non-smokers exposed to secondhand smoke. Some of the highest levels of NNK and NNN are found in U.S. products. It is well established that factors such as choice of tobacco blend, agricultural conditions, and processing methods influence levels of NNK and NNN in cigarette tobacco and cigarette smoke. Therefore, it is time to control these factors and produce cigarettes with 100 ppb or less each of NNK and NNN in tobacco, which would result in an approximate 15-20 fold reduction of these carcinogens in the mainstream smoke of popular cigarettes sold in the United States. PMID:24806664

  5. Precursor/product studies of macrophage synthesis of nitrite, nitrate and N-nitrosamines

    International Nuclear Information System (INIS)

    Iyengar, R.; Marletta, M.A.

    1987-01-01

    Previous experiments showed that nitrite, nitrate and N-nitrosamine synthesis was carried out by both stimulated macrophages (M phi) and a number of M phi cell lines. Here the authors report the precursor to NO 2 - , NO 3 - , and the source of the nitrosating agent. Previous kinetic studies established a time lag for NO 2 - /NO 3 - synthesis during which protein synthesis required for product formation occurred. Medium change after the protein synthesis phase showed that L-arginine was the only amino acid essential for the synthesis. Other precursors were homoarginine, arginine methyl ester, arginine infinity-hydroxamate, argininamide and the peptide arginine-aspartate. Glutamine, citrulline, ornithine, hydroxylamine and D-arginine were among some of the non-precursors. Canavanine though not a precursor inhibited arginine-derived NO 2 -/NO 3 - synthesis while D-arginine had no effect. When 15 N-arginine (guanido- 15 N 2 , 95%) was used, GC/MS results showed that all the NO 2 - /NO 3 - synthesized was derived exclusively from these two guanido nitrogens. Similar labeling experiments carried out in the presence of morpholine showed that the isotopic enrichment of N-nitrosomorpholine was the same as that of NO 2 - /NO 3 - synthesized, suggesting that the nitrosating agent is a common intermediate. In conclusion, NO 2 - /NO 3 - and N-nitrosomorpholine synthesis by stimulated macrophages is derived specifically from the two guanido nitrogens of arginine

  6. The Possible HEPATOPROTECTIVE Effect Of Taurine In Diethyl Nitrosamine (DEN) Treated Rats

    International Nuclear Information System (INIS)

    SHAROUD, M.N.M.; ABD EL-MONEIM, A.E.

    2009-01-01

    Egypt occupies a progressed rank among the developing countries in prevalence of hepatic diseases and liver disorders. Hepatopathies are major public health problems in Egypt where hepatitis C virus (HCV) and schistosomia record a high prevalence which may account for the most serious clinical disorders e.g. liver cirrhosis and liver cancer.Vascular endothelial growth factor (VEGF) is the most specific and potent mitogen of endothelial cells. Hepatocellular carcinoma (HCC) is characterized by increased pathologic angio genesis and increased level of the vascular endothelial growth factor. Taurine is clinically used as a protecting agent of the liver and recently, its chemo preventive effect on rat large bowel carcinogenesis was reported.In this study, forty male albino rats were used and diethyl nitrosamine (DEN) was used for inducing pathological changes in different organs while taurine was given to investigate the possible protective effects on liver tissue after DEN treatment.The results showed elevation in serum AST, ALT, ALP, urea, creatinine, cholesterol and triglycerides in DEN group. On the other hand, estimation of sex hormones exhibited marked decrease in testosterone and significant increase in estradiol levels in DEN group as compared to control and taurine groups.Pathological examination of rat liver showed that DEN induced peri portal inflammatory cellular infiltrate, piece meal necrosis and necro inflammatory activity as well as the appearance of areas of haemorrhage and ballooning in hepatocytes. Moreover, moderate to high expression of V EGF in the cytoplasm of hepatocytes and sinusoidal cells were clearly observed while in control and taurine groups, normal architecture of hepatic tissue of rats was found and normal distribution of V EGF as diffuse or focal granular cytoplasmic stain in rats liver were observed. The prophylactic group showed minimal and mild changes in the liver tissue with absence of necro inflammation and the V EGF expression

  7. Analysis of undergraduate cell biology contents in Brazilian public universities.

    Science.gov (United States)

    Mermelstein, Claudia; Costa, Manoel Luis

    2017-04-01

    The enormous amount of information available in cell biology has created a challenge in selecting the core concepts we should be teaching our undergraduates. One way to define a set of essential core ideas in cell biology is to analyze what a specific cell biology community is teaching their students. Our main objective was to analyze the cell biology content currently being taught in Brazilian universities. We collected the syllabi of cell biology courses from public universities in Brazil and analyzed the frequency of cell biology topics in each course. We also compared the Brazilian data with the contents of a major cell biology textbook. Our analysis showed that while some cell biology topics such as plasma membrane and cytoskeleton was present in ∼100% of the Brazilian curricula analyzed others such as cell signaling and cell differentiation were present in only ∼35%. The average cell biology content taught in the Brazilian universities is quite different from what is presented in the textbook. We discuss several possible explanations for these observations. We also suggest a list with essential cell biology topics for any biological or biomedical undergraduate course. The comparative discussion of cell biology topics presented here could be valuable in other educational contexts. © 2017 The Authors. Cell Biology International Published by John Wiley & Sons Ltd on behalf of International Federation of Cell Biology.

  8. Science Concierge: A Fast Content-Based Recommendation System for Scientific Publications.

    Science.gov (United States)

    Achakulvisut, Titipat; Acuna, Daniel E; Ruangrong, Tulakan; Kording, Konrad

    2016-01-01

    Finding relevant publications is important for scientists who have to cope with exponentially increasing numbers of scholarly material. Algorithms can help with this task as they help for music, movie, and product recommendations. However, we know little about the performance of these algorithms with scholarly material. Here, we develop an algorithm, and an accompanying Python library, that implements a recommendation system based on the content of articles. Design principles are to adapt to new content, provide near-real time suggestions, and be open source. We tested the library on 15K posters from the Society of Neuroscience Conference 2015. Human curated topics are used to cross validate parameters in the algorithm and produce a similarity metric that maximally correlates with human judgments. We show that our algorithm significantly outperformed suggestions based on keywords. The work presented here promises to make the exploration of scholarly material faster and more accurate.

  9. An Investigation of the Amount of Emphasis Placed on Content and Delivery by Instructors of Public Speaking.

    Science.gov (United States)

    Siddens, Paul J., III

    A study examined how much emphasis instructors of public speaking place on content and delivery when teaching and delivering oral and written critiques. The study sought to determine whether when teaching a hybrid introduction to communication course, or public speaking course, instructors are challenged with teaching their students about issues…

  10. Tobacco-specific N-nitrosamines NNN and NNK levels in cigarette brands between 2000 and 2014.

    Science.gov (United States)

    Gunduz, I; Kondylis, A; Jaccard, G; Renaud, J-M; Hofer, R; Ruffieux, L; Gadani, F

    2016-04-01

    The evolution of the levels of tobacco-specific N-nitrosamines (TSNA), N-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mainstream (MS) cigarette smoke is investigated based on smoke and tobacco chemistry data of cigarette brands sold by Philip Morris International (PMI) between 2000 and 2014. A total of 315 cigarette samples representing a wide range of product and design characteristics manufactured by PMI between 2008 and 2014 were analyzed and compared to a previously published dataset of PMI brands manufactured in 2000. The data indicate that there is a substantial reduction of NNN and NNK levels in tobacco fillers and MS cigarette smoke per mg of tar and per mg of nicotine using Health Canada Intense (HCI) machine-smoking regime. This observed reduction in NNN and NNK levels in MS cigarette smoke is also supported by the downward trend observed on NNN and NNK levels in USA flue-cured Virginia and Burley tobacco lots from 2000 to 2014 crops, reflecting effectiveness of measures taken on curing and agricultural practices designed to minimize TSNA formation in tobacco. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  11. Anticancer activity of Cynodon dactylon L. root extract against diethyl nitrosamine induced hepatic carcinoma.

    Science.gov (United States)

    Kowsalya, R; Kaliaperumal, Jagatheesh; Vaishnavi, M; Namasivayam, Elangovan

    2015-01-01

    Hepatocellular carcinoma is one of the most common cancers and a lethal disease. In view of the limited treatment and a grave prognosis of liver cancer, preventive control has been emphasized. The methanolic extract of roots of Cynodon dactylon was screened for its hepato-protective activity in diethyl nitrosamine (DEN) induced liver cancer in Swiss albino mice. The plant extract at a dose of 50 mg/kg was administered orally once a week, up to 30 days after DEN administration. The animals were sacrificed; blood sample and liver tissue were collected and used for enzyme assay such as, asparatate amino transferase (AST), alanine aminotransferase (ALT), catalase (CAT), glutathione peroxidase (GPx) and glutathione-S-transferase (GST). The liver marker enzymes AST and ALT produced significant results in the protective action. The antioxidant enzyme assay results concerning the improved activity of GPx, GST and CAT. These results concluded that enhanced levels of antioxidant enzyme and reduced amount of serum amino transaminase, which are suggested to be the major mechanisms of C. dactylon root extract in protecting the mice from hepatocarcinoma induced by DEN. These biochemical observations were supplemented by histopathological examination of liver sections. The methanolic extract of C. dactylon possesses significant anticancer properties.

  12. Anticancer activity of Cynodon dactylon L. root extract against diethyl nitrosamine induced hepatic carcinoma

    Directory of Open Access Journals (Sweden)

    R Kowsalya

    2015-01-01

    Full Text Available Background: Hepatocellular carcinoma is one of the most common cancers and a lethal disease. In view of the limited treatment and a grave prognosis of liver cancer, preventive control has been emphasized. Materials and Methods: The methanolic extract of roots of Cynodon dactylon was screened for its hepato-protective activity in diethyl nitrosamine (DEN induced liver cancer in Swiss albino mice. The plant extract at a dose of 50 mg/kg was administered orally once a week, up to 30 days after DEN administration. The animals were sacrificed; blood sample and liver tissue were collected and used for enzyme assay such as, asparatate amino transferase (AST, alanine aminotransferase (ALT, catalase (CAT, glutathione peroxidase (GPx and glutathione-S-transferase (GST. The liver marker enzymes AST and ALT produced signifi cant results in the protective action. Results: The antioxidant enzyme assay results concerning the improved activity of GPx, GST and CAT. These results concluded that enhanced levels of antioxidant enzyme and reduced amount of serum amino transaminase, which are suggested to be the major mechanisms of C. dactylon root extract in protecting the mice from hepatocarcinoma induced by DEN. These biochemical observations were supplemented by histopathological examination of liver sections. Conclusion: The methanolic extract of C. dactylon possesses signifi cant anticancer properties

  13. Science Concierge: A Fast Content-Based Recommendation System for Scientific Publications.

    Directory of Open Access Journals (Sweden)

    Titipat Achakulvisut

    Full Text Available Finding relevant publications is important for scientists who have to cope with exponentially increasing numbers of scholarly material. Algorithms can help with this task as they help for music, movie, and product recommendations. However, we know little about the performance of these algorithms with scholarly material. Here, we develop an algorithm, and an accompanying Python library, that implements a recommendation system based on the content of articles. Design principles are to adapt to new content, provide near-real time suggestions, and be open source. We tested the library on 15K posters from the Society of Neuroscience Conference 2015. Human curated topics are used to cross validate parameters in the algorithm and produce a similarity metric that maximally correlates with human judgments. We show that our algorithm significantly outperformed suggestions based on keywords. The work presented here promises to make the exploration of scholarly material faster and more accurate.

  14. Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: alternative approaches.

    Science.gov (United States)

    Buist, H E; Devito, S; Goldbohm, R A; Stierum, R H; Venhorst, J; Kroese, E D

    2015-04-01

    Carbon capture and storage (CCS) technologies are considered vital and economic elements for achieving global CO2 reduction targets, and is currently introduced worldwide (for more information on CCS, consult for example the websites of the International Energy Agency (http://www.iea.org/topics/ccs/) and the Global CCS Institute (http://www.globalccsinstitute.com/)). One prominent CCS technology, the amine-based post-combustion process, may generate nitrosamines and their related nitramines as by-products, the former well known for their potential mutagenic and carcinogenic properties. In order to efficiently assess the carcinogenic potency of any of these by-products this paper reviews and discusses novel prediction approaches consuming less time, money and animals than the traditionally applied 2-year rodent assay. For this, available animal carcinogenicity studies with N-nitroso compounds and nitramines have been used to derive carcinogenic potency values, that were subsequently used to assess the predictive performance of alternative prediction approaches for these chemicals. Promising cancer prediction models are the QSARs developed by the Helguera group, in vitro transformation assays, and the in vivo initiation-promotion, and transgenic animal assays. All these models, however, have not been adequately explored for this purpose, as the number of N-nitroso compounds investigated is yet too limited, and therefore further testing with relevant N-nitroso compounds is needed. Copyright © 2015. Published by Elsevier Inc.

  15. Tobacco-Specific Nitrosamines in Electronic Cigarettes: Comparison between Liquid and Aerosol Levels

    Directory of Open Access Journals (Sweden)

    Konstantinos E. Farsalinos

    2015-07-01

    Full Text Available Introduction: Although electronic cigarette (EC liquids contain low levels of tobacco-specific nitrosamines (TSNAs, studies evaluating the levels emitted to the aerosol are scarce. The purpose of this study was to compare the levels of TSNAs between liquids and generated aerosol. Methods: Three EC liquids were obtained from the market. An additional (spiked sample was prepared by adding known amounts of standard TSNAs solutions to one of the obtained liquids. N-nitrosonornicotine (NNN, N-nitrosoanatabine (NAT, N-nitrosoanabasine (NAB and 4-(methylnitrosamino1-(3-pyridyl-1-butanone (NNK were measured. Three 100-puff sets from each liquid were trapped in filter pads and were subsequently analyzed for the presence of TSNAs. The expected levels of TSNAs (calculated based on the liquid consumption were compared with the measured levels in the aerosol. Results: Only NAB was found at trace levels in two commercial liquids (1.2 and 2.3 ng/g, while the third contained 1.5 ng/g NAB and 7.7 ng/g NNN. The 100-puff sets resulted in 336–515 mg liquid consumption, with no TSNAs being detected in the aerosol. The spiked sample contained 42.0–53.9 ng/g of each of the TSNAs. All TSNAs were detected in the aerosol with the measured levels being statistically similar to the expected amounts. A significant correlation between expected and measured levels of TSNAs in the aerosol was found (r = 0.83, p < 0.001. Conclusion: The findings of this study show that exposure of EC users to TSNAs can be accurately assessed based on the levels present in the liquid, without the need to analyze the aerosol.

  16. Effects of Phenobarbital and Carbazole on Carcinogenesis of the Lung, Thyroid, Kidney, and Bladder of Rats Pretreated with N‐Bis(2‐hydroxypropyl)nitrosamine

    Science.gov (United States)

    Masuda, Atsuko; Imaida, Katsumi; Ogiso, Tadashi; Ito, Nobuyuki

    1988-01-01

    Studies were made on potential modifying effects of phenobarbital (PB) and carbazole on tumor development induced by N‐bis(2‐hydroxypropyl)nitrosamine (DHPN), a wide‐spectrum carcinogen in rats. Effects on the lung, thyroid, kidney, bladder and liver were investigated. Male F344 rats were given 0.2% DHPN in their drinking water for 1 week and then 0.05% PB or 0.6% carbazole in their diet for 50 weeks. Control animals were treated with either DHPN or PB or carbazole only. Neither PB nor carbazole affected the incidence or histology of lung tumors. However, PB promoted the development of thyroid tumors and preneoplastic lesions of the liver, while carbazole promoted the induction of renal pelvic tumors. PMID:3133336

  17. Antimutagenic and anticarcinogenic effects of betel leaf extract against the tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK).

    Science.gov (United States)

    Bhide, S V; Padma, P R; Amonkar, A J

    1991-01-01

    Earlier studies showed that betel leaf inhibits the mutagenic action of standard mutagens like benzo[a]pyrene and dimethylbenz[a]anthracene. Since tobacco-specific nitrosamines are the major carcinogens present in unburnt forms of tobacco, we studied the effect of an extract of betel leaf on the mutagenic and carcinogenic actions of one of the most potent, 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK). Betel-leaf extract and hydroxychavicol suppressed the mutagenicity of NNK in both the Ames and the micronucleus test. In studies in mice, betel-leaf extract reduced the tumorigenic effects of NNK by 25%. Concurrent treatment with the extract also inhibited the decreases in levels of vitamin A in liver and plasma induced by NNK. Betel leaf thus has protective effects against the mutagenic, carcinogenic and adverse metabolic effects of NNK in mice.

  18. Visualizing Public Opinion in Croatia Based on Available Social Network Content

    Directory of Open Access Journals (Sweden)

    Ševa, Jurica

    2016-01-01

    Full Text Available In the last decade advances of computer technologies have lead towards a technological reality where the line between information consumers and information producers is blurred. This technological omnipresence allows for unprecedented data creation capabilities. Based on various data sources, it seems humans have fully embraced data-generating activities. One such activity is using online social network applications, like Facebook or Twitter in almost all aspects of their lives. One of the main features of online social network applications is perceived freedom of speech, individuality and privacy, even though every application has some special features. Therefore, content generated using these services presents the public with interesting insights in private life of people and their attitudes towards public affairs. Social network applications are active the most during specific public events aimed at the massive public. Due to its brevity, ease of use and frequency, Twitter is an interesting social network application for research and analysis. Other than allowing almost exclusively short messages (up to 140 characters, a tweet (a Twitter post can contain location of the message sender as well as a graphic to accompany the textual message. The textual part of the message may contain so called hashtags – keywords used for indexing and easy identification of a subject the message is related to. These hashtags allow us to group messages related to a specific event. Recent governmental elections held in Croatia were very popular amongst the Croatian Twitter community. Usage of hashtags allowed us to identify the right messages and thus most-used words to describe this event and potentially identify how people felt when talking, i.e. writing, about politics and the held elections. Furthermore, geolocation information, optionally embedded in a tweet, makes it possible to analyze which keywords were used in which parts of Croatia, all pertaining to

  19. African Journal of Biomedical Research - Vol 3, No 3 (2000)

    African Journals Online (AJOL)

    Formation of toxic nitrosamine as a complication of prostatic hyperplasma ... on trace element contents of the skin and pelace of west African dwarf (WAD) goat ... Double cervix in a five-year-old white Fulami cow · EMAIL FREE FULL TEXT ...

  20. Dietary Nitrates, Nitrites, and Nitrosamines Intake and the Risk of Gastric Cancer: A Meta-Analysis.

    Science.gov (United States)

    Song, Peng; Wu, Lei; Guan, Wenxian

    2015-12-01

    The potential associations between dietary consumption of nitrates, nitrites, and nitrosamines and gastric cancer risk have been investigated by several studies, but yielded inconclusive results. We conducted a meta-analysis to provide a quantitative assessment of their relationships. Relevant articles were identified by a systematic literature searching of PubMed and Embase databases prior to August 2015. Random-effects models were employed to pool the relative risks. A total of 22 articles consisting of 49 studies-19 studies for nitrates, 19 studies for nitrites, and 11 studies for N-nitrosodimethylamine (NDMA)-were included. The summary relative risk of stomach cancer for the highest categories, compared with the lowest, was 0.80 (95% confidence interval (CI), 0.69-0.93) for dietary nitrates intake, 1.31 (95% CI, 1.13-1.52) for nitrites, and 1.34 (95% CI, 1.02-1.76) for NDMA (p for heterogeneity was 0.015, 0.013 and nitrates and nitrites. The heterogeneity for NDMA could not be eliminated completely through stratified analysis. Although significant associations were all observed in case-control studies, the cohort studies still showed a slight trend. The dose-response analysis indicated similar results as well. High nitrates intake was associated with a weak but statistically significant reduced risk of gastric cancer. Whereas increased consumption of nitrites and NDMA seemed to be risk factors for cancer. Due to the lack of uniformity for exposure assessment across studies, further prospective researches are warranted to verify these findings.

  1. Dietary Nitrates, Nitrites, and Nitrosamines Intake and the Risk of Gastric Cancer: A Meta-Analysis

    Science.gov (United States)

    Song, Peng; Wu, Lei; Guan, Wenxian

    2015-01-01

    The potential associations between dietary consumption of nitrates, nitrites, and nitrosamines and gastric cancer risk have been investigated by several studies, but yielded inconclusive results. We conducted a meta-analysis to provide a quantitative assessment of their relationships. Relevant articles were identified by a systematic literature searching of PubMed and Embase databases prior to August 2015. Random-effects models were employed to pool the relative risks. A total of 22 articles consisting of 49 studies—19 studies for nitrates, 19 studies for nitrites, and 11 studies for N-nitrosodimethylamine (NDMA)—were included. The summary relative risk of stomach cancer for the highest categories, compared with the lowest, was 0.80 (95% confidence interval (CI), 0.69–0.93) for dietary nitrates intake, 1.31 (95% CI, 1.13–1.52) for nitrites, and 1.34 (95% CI, 1.02–1.76) for NDMA (p for heterogeneity was 0.015, 0.013 and NDMA could not be eliminated completely through stratified analysis. Although significant associations were all observed in case-control studies, the cohort studies still showed a slight trend. The dose-response analysis indicated similar results as well. High nitrates intake was associated with a weak but statistically significant reduced risk of gastric cancer. Whereas increased consumption of nitrites and NDMA seemed to be risk factors for cancer. Due to the lack of uniformity for exposure assessment across studies, further prospective researches are warranted to verify these findings. PMID:26633477

  2. A Model To Estimate the Sources of Tobacco-Specific Nitrosamines in Cigarette Smoke.

    Science.gov (United States)

    Lipowicz, Peter J; Seeman, Jeffrey I

    2017-08-21

    Tobacco-specific nitrosamines (TSNAs) are one of the most extensively and continually studied classes of compounds found in tobacco and cigarette smoke.1-5 The TSNAs N-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) have been characterized by the US Food and Drug Administration (FDA) as harmful and potentially harmful constituents in tobacco products,6 and cigarette manufacturers report their levels in cigarette tobacco filler and cigarette smoke to the FDA. NNN and NNK are classified by IARC as carcinogenic to humans.7 TSNAs transfer from tobacco to smoke by evaporation driven by heat and the flow of gases down the cigarette rod. Other TSNA sources in smoke include pyrorelease, where room temperature-unextractable TSNAs are released by smoking, and pyrosynthesis, where TSNAs are formed by reactions during smoking. We propose the first model that quantifies these three sources of TSNA in smoke. In our model, evaporative transfer efficiency of a TSNA is equated to the evaporative transfer efficiency of nicotine. Smoke TSNA measured in excess of what is transferred by evaporation is termed "pyrogeneration," which is the net sum of pyrorelease and pyrosynthesis minus pyrodegredation. This model requires no internal standard, is applicable to commercial cigarettes "as is," and uses existing analytical methods. This model was applied to archived Philip Morris USA data. For commercial blended cigarettes, NNN pyrogeneration appears to be unimportant, but NNK pyrogeneration contributes roughly 30-70% of NNK in smoke with the greater contribution at lower tobacco NNK levels. This means there is an opportunity to significantly reduce smoke NNK by up to 70% if pyrogeneration can be decreased or eliminated, perhaps by finding a way to grow and cure tobacco with reduced matrix-bound NNK. For burley research cigarettes, pyrogeneration may account for 90% or more of both NNN and NNK in smoke.

  3. The national public's values and interests related to the Arctic National Wildlife Refuge: A computer content analysis

    Science.gov (United States)

    David N. Bengston; David P. Fan; Roger Kaye

    2010-01-01

    This study examined the national public's values and interests related to the Arctic National Wildlife Refuge. Computer content analysis was used to analyze more than 23,000 media stories about the refuge from 1995 through 2007. Ten main categories of Arctic National Wildlife Refuge values and interests emerged from the analysis, reflecting a diversity of values,...

  4. Tobacco Product Use Patterns, and Nicotine and Tobacco-Specific Nitrosamine Exposure: NHANES 1999-2012.

    Science.gov (United States)

    Choi, Kelvin; Sabado, Melanie; El-Toukhy, Sherine; Vogtmann, Emily; Freedman, Neal D; Hatsukami, Dorothy

    2017-10-01

    Background: Few studies have examined differences in product consumption patterns and nicotine and tobacco-specific nitrosamines (TSNA) exposure between single versus dual- and poly-tobacco users. We applied the Tobacco Product Use Patterns (T-PUPs) model to fill this gap in the literature. Methods: Data from adults (age ≥18 years) who used any tobacco products during the 5 days prior to participating in the 1999-2012 National Health and Nutrition Examination Survey (NHANES) were analyzed. Participants were classified into seven T-PUPs: (1) cigarettes only, (2) noncigarette combustibles only, (3) noncombustibles only, (4) dual noncigarette combustibles and noncombustibles, (5) dual cigarettes and noncombustibles, (6) dual cigarettes and noncigarette combustibles, and (7) poly-tobacco use. Weighted regression models were used to compare product consumption, serum cotinine, and urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (i.e., NNAL) levels between single-, dual-, and poly-tobacco T-PUPs. Results: Dual- and poly-tobacco T-PUPs were associated with lower product consumption compared with single-product T-PUPs only in some cases (e.g., dual cigarette and noncombustible users smoked cigarettes on 0.6 fewer days in the past 5 days compared with cigarette-only users; P product T-PUPs. Conclusions: Product consumption, and nicotine and TSNAs exposure of dual- and poly-tobacco product category users somewhat differ from those of single-product category users as defined by the T-TUPs model. Impact: Higher levels of cotinine and NNAL among dual- and poly-tobacco T-TUPs users compared with the single-product T-TUPs users may indicate health concerns. Cancer Epidemiol Biomarkers Prev; 26(10); 1525-30. ©2017 AACR . ©2017 American Association for Cancer Research.

  5. A New Automated Method and Sample Data Flow for Analysis of Volatile Nitrosamines in Human Urine*

    Science.gov (United States)

    Hodgson, James A.; Seyler, Tiffany H.; McGahee, Ernest; Arnstein, Stephen; Wang, Lanqing

    2016-01-01

    Volatile nitrosamines (VNAs) are a group of compounds classified as probable (group 2A) and possible (group 2B) carcinogens in humans. Along with certain foods and contaminated drinking water, VNAs are detected at high levels in tobacco products and in both mainstream and sidestream smoke. Our laboratory monitors six urinary VNAs—N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosodiethylamine (NDEA), N-nitrosopiperidine (NPIP), N-nitrosopyrrolidine (NPYR), and N-nitrosomorpholine (NMOR)—using isotope dilution GC-MS/MS (QQQ) for large population studies such as the National Health and Nutrition Examination Survey (NHANES). In this paper, we report for the first time a new automated sample preparation method to more efficiently quantitate these VNAs. Automation is done using Hamilton STAR™ and Caliper Staccato™ workstations. This new automated method reduces sample preparation time from 4 hours to 2.5 hours while maintaining precision (inter-run CV < 10%) and accuracy (85% - 111%). More importantly this method increases sample throughput while maintaining a low limit of detection (<10 pg/mL) for all analytes. A streamlined sample data flow was created in parallel to the automated method, in which samples can be tracked from receiving to final LIMs output with minimal human intervention, further minimizing human error in the sample preparation process. This new automated method and the sample data flow are currently applied in bio-monitoring of VNAs in the US non-institutionalized population NHANES 2013-2014 cycle. PMID:26949569

  6. Islamic-Content-TED Public Speaking as a Source Material for Improving Islamic Student’s Communication Skill

    Directory of Open Access Journals (Sweden)

    Lyla Anggerwina Kusuma

    2017-10-01

    Full Text Available In applying communicative competence that became the utmost teaching method in teaching English program, the lecturers found the fact that the Islamic communication students are apparently reluctant to speak and communicate their ideas confidently. It happens because they thought that they do not know what they are going to say and how they are going to say their ideas. By knowing these problems the lecturers then tried to analyze the sequences of Islamic-content-TED and integrate those public speaking sequences from TED talks to STID Al-Hadid’s students to give an understanding and also to improve the confidence and quality in delivering public speaking speech for the sophomore students who are majoring Islamic Communication & Broadcasting. For further, in order to master this skill, students are also expected to find noble ideas to be shared in their personal public speaking. This action research study then found out that having sharing the sequences of TED talks, the student’s public speaking productions are more organized and powerful moreover; the fluency and also the student’s accuracy of the students could be controlled well.

  7. A STUDY OF THE REQUIRED PUBLIC ACCOUNTING PROGRAM IN PUBLIC COMPETITIVE EXAMINATIONS HELD BY CESPE

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    Fátima de Souza Freire

    2012-11-01

    Full Text Available With a view to standardizing the contents offered to future Accounting professionals, the Federal Accounting Council (CFC elaborated the National Proposal for Undergraduate Accountancy Program Contents. Thus, the curriculum that Higher Education Institutions (HEI adopt serves as an ally for students’ professional conquests. Stability and favorable job conditions attract many people to the dispute for a public function, with a growing Braz ilian public competitive examination market. According to the National Association for Protection and Support to Public Competitive Examinations (Anpac, between 2003 and 2009, the number of public servants in the executive power with a higher education degree in Brazil increased by 26%. The aim of this study was to confront the CFC’s suggested knowledge with the contents required during tests applied in public competitive examinations for Accountancy professionals. The intent is to identify what Public Accounting knowledge is demanded from candidates for the public career. Through a documentary research, 561 calls from public competitive examinations exclusively for Accountancy professionals were selected for the study sample. They were classified according to the proposed program contents, the test questions by the Center for Selection and Event Promotion (Cespe, between 2000 and 2009. In conclusion, the most frequent required Public Accounting areas are contents related to Public Equity and Budget. The results demonstrate that the CFC’s suggested content is in line with the knowledge required from candidates for public functions.

  8. Facile and sensitive determination of N-nitrosamines in food samples by high-performance liquid chromatography via combining fluorescent labeling with dispersive liquid-liquid microextraction.

    Science.gov (United States)

    Lu, Shuaimin; Wu, Di; Li, Guoliang; Lv, Zhengxian; Gong, Peiwei; Xia, Lian; Sun, Zhiwei; Chen, Guang; Chen, Xuefeng; You, Jinmao; Wu, Yongning

    2017-11-01

    The intake of N-nitrosamines (NAs) from foodstuffs is considered to be an important influence factor for several cancers. But the rapid and sensitive screening of NAs remains a challenge in the field of food safety. Inspired by that, a sensitive and rapid method was demonstrated for determination of five NAs (Nitrosopyrrolidine, Nitrosodimethylamine, Nitrosodiethylamine, Nitrosodipropylamine and Nitrosodibutylamine) using dispersive liquid-liquid microextraction (DLLME) followed by high-performance liquid chromatography with fluorescence detection (HPLC-FLD). The NAs were firstly denitrosated and labeled by 2-(11H-benzo[a]carbazol-11-yl) ethyl carbonochloridate (BCEC-Cl) and finally enriched by DLLME. Furthermore, the main DLLME conditions were optimized systematically. Under the optimal conditions, satisfactory limits of detection (LODs) were obtained with a range of 0.01-0.07ngg -1 , which were significantly lower than the reported methods. The developed method showed many merits including rapidity, simplicity, high sensitivity and excellent selectivity, which shows a broad prospect in food safety analysis. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Using Structured Observation and Content Analysis to Explore the Presence of Older People in Public Fora in Developing Countries

    Directory of Open Access Journals (Sweden)

    Geraldine Nosowska

    2014-01-01

    Full Text Available There is a lack of research on the everyday lives of older people in developing countries. This exploratory study used structured observation and content analysis to examine the presence of older people in public fora and considered the methods’ potential for understanding older people’s social integration and inclusion. Structured observation occurred of public social spaces in six cities each located in a different developing country and in one city in the United Kingdom, together with content analysis of the presence of people in newspaper pictures and on television in the selected countries. Results indicated that across all fieldwork sites and data sources, there was a low presence of older people, with women considerably less present than men in developing countries. There was variation across fieldwork sites in older people’s presence by place and time of day and in their accompanied status. The presence of older people in images drawn from newspapers was associated with the news/non-news nature of the source. The utility of the study’s methodological approach is considered, as is the degree to which the presence of older people in public fora might relate to social integration and inclusion in different cultural contexts.

  10. Objective coding of content and techniques in workplace-based supervision of an EBT in public mental health.

    Science.gov (United States)

    Dorsey, Shannon; Kerns, Suzanne E U; Lucid, Leah; Pullmann, Michael D; Harrison, Julie P; Berliner, Lucy; Thompson, Kelly; Deblinger, Esther

    2018-01-24

    Workplace-based clinical supervision as an implementation strategy to support evidence-based treatment (EBT) in public mental health has received limited research attention. A commonly provided infrastructure support, it may offer a relatively cost-neutral implementation strategy for organizations. However, research has not objectively examined workplace-based supervision of EBT and specifically how it might differ from EBT supervision provided in efficacy and effectiveness trials. Data come from a descriptive study of supervision in the context of a state-funded EBT implementation effort. Verbal interactions from audio recordings of 438 supervision sessions between 28 supervisors and 70 clinicians from 17 public mental health organizations (in 23 offices) were objectively coded for presence and intensity coverage of 29 supervision strategies (16 content and 13 technique items), duration, and temporal focus. Random effects mixed models estimated proportion of variance in content and techniques attributable to the supervisor and clinician levels. Interrater reliability among coders was excellent. EBT cases averaged 12.4 min of supervision per session. Intensity of coverage for EBT content varied, with some discussed frequently at medium or high intensity (exposure) and others infrequently discussed or discussed only at low intensity (behavior management; assigning/reviewing client homework). Other than fidelity assessment, supervision techniques common in treatment trials (e.g., reviewing actual practice, behavioral rehearsal) were used rarely or primarily at low intensity. In general, EBT content clustered more at the clinician level; different techniques clustered at either the clinician or supervisor level. Workplace-based clinical supervision may be a feasible implementation strategy for supporting EBT implementation, yet it differs from supervision in treatment trials. Time allotted per case is limited, compressing time for EBT coverage. Techniques that

  11. Directing the public to evidence-based online content.

    Science.gov (United States)

    Cooper, Crystale Purvis; Gelb, Cynthia A; Vaughn, Alexandra N; Smuland, Jenny; Hughes, Alexandra G; Hawkins, Nikki A

    2015-04-01

    To direct online users searching for gynecologic cancer information to accurate content, the Centers for Disease Control and Prevention's (CDC) 'Inside Knowledge: Get the Facts About Gynecologic Cancer' campaign sponsored search engine advertisements in English and Spanish. From June 2012 to August 2013, advertisements appeared when US Google users entered search terms related to gynecologic cancer. Users who clicked on the advertisements were directed to relevant content on the CDC website. Compared with the 3 months before the initiative (March-May 2012), visits to the CDC web pages linked to the advertisements were 26 times higher after the initiative began (June-August 2012) (padvertisements were supplemented with promotion on television and additional websites (September 2012-August 2013) (padvertisements can direct users to evidence-based content at a highly teachable moment--when they are seeking relevant information. © The Author 2014. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. Dietary Nitrates, Nitrites, and Nitrosamines Intake and the Risk of Gastric Cancer: A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Peng Song

    2015-12-01

    Full Text Available The potential associations between dietary consumption of nitrates, nitrites, and nitrosamines and gastric cancer risk have been investigated by several studies, but yielded inconclusive results. We conducted a meta-analysis to provide a quantitative assessment of their relationships. Relevant articles were identified by a systematic literature searching of PubMed and Embase databases prior to August 2015. Random-effects models were employed to pool the relative risks. A total of 22 articles consisting of 49 studies—19 studies for nitrates, 19 studies for nitrites, and 11 studies for N-nitrosodimethylamine (NDMA—were included. The summary relative risk of stomach cancer for the highest categories, compared with the lowest, was 0.80 (95% confidence interval (CI, 0.69–0.93 for dietary nitrates intake, 1.31 (95% CI, 1.13–1.52 for nitrites, and 1.34 (95% CI, 1.02–1.76 for NDMA (p for heterogeneity was 0.015, 0.013 and <0.001, respectively. The study type was found as the main source of heterogeneity for nitrates and nitrites. The heterogeneity for NDMA could not be eliminated completely through stratified analysis. Although significant associations were all observed in case-control studies, the cohort studies still showed a slight trend. The dose-response analysis indicated similar results as well. High nitrates intake was associated with a weak but statistically significant reduced risk of gastric cancer. Whereas increased consumption of nitrites and NDMA seemed to be risk factors for cancer. Due to the lack of uniformity for exposure assessment across studies, further prospective researches are warranted to verify these findings.

  13. Gender perspectives on access to public debate: reflecting on the evening news contents

    Directory of Open Access Journals (Sweden)

    Rosa Cabecinhas

    2013-06-01

    Full Text Available The present article aims to analyze the reception of media content within a gender perspective. The women’s full exercise of citizenship and access to public debate depends greatly on the way media presents them to the world. This study considers that balanced representation of men and women in the news is an important criterion to take into account in order to produce quality journalism. Considering the various television news programs, the evening news is definitely one of the most important and, yet, one of the less studied. Daily broadcast on a prime time schedule, it is considered to be an important source of information through which citizens acknowledge themain events of the news agenda and, also, their social roles and responsibilities. Therefore, several focus groups have been organized with the purpose of debating news contents and understanding how gender meanings are negotiated by audiences. The analysis of these debates displayed important gender perspectives among focus groups participants. Its outputs allowed a better understanding of how audiences interpret gender meanings in the media and emphasized the need to develop alternative proposals of journalistic practices capable of promoting a critical, balanced and diversified gender perspective within the audiences.

  14. Agonist and antagonist effects of tobacco-related nitrosamines on human α4β2 nicotinic acetylcholine receptors.

    Directory of Open Access Journals (Sweden)

    Simone eBrusco

    2015-09-01

    Full Text Available Regulation of the ‘neuronal’ nicotinic acetylcholine receptors (nAChRs is implicated in both tobacco addiction and smoking-dependent tumor promotion. Some of these effects are caused by the tobacco-derived N-nitrosamines, which are carcinogenic compounds that avidly bind to nAChRs. However, the functional effects of these drugs on specific nAChR subtypes are largely unknown. By using patch-clamp methods, we tested 4-(methylnitrosamine-1-(3-pyridyl-1-butanone (NNK and N’-nitrosonornicotine (NNN on human α4β2 nAChRs. These latter are widely distributed in the mammalian brain and are also frequently expressed outside the nervous system. NNK behaved as a partial agonist, with an apparent EC50 of 16.7 μM. At 100 μM, it activated 16 % of the maximal current activated by nicotine. When NNK was co-applied with nicotine, it potentiated the currents elicited by nicotine concentrations ≤ 100 nM. At higher concentrations of nicotine, NNK always inhibited the α4β2 nAChR. In contrast, NNN was a pure inhibitor of this nAChR subtype, with IC50 of approximately 1 nM in the presence of 10 μM nicotine. The effects of both NNK and NNN were mainly competitive and largely independent of Vm. The different actions of NNN and NNK must be taken into account when interpreting their biological effects in vitro and in vivo.

  15. A new strategy for umbilical cord blood collection developed at the first Colombian public cord blood bank increases total nucleated cell content.

    Science.gov (United States)

    Vanegas, Diana; Triviño, Lady; Galindo, Cristian; Franco, Leidy; Salguero, Gustavo; Camacho, Bernardo; Perdomo-Arciniegas, Ana-María

    2017-09-01

    The total nucleated cell dosage of umbilical cord blood (UCB) is an important factor in determining successful allogeneic hematopoietic stem cell transplantation after a minimum human leukocyte antigen donor-recipient match. The northern South American population is in need of a new-generation cord blood bank that cryopreserves only units with high total nucleated cell content, thereby increasing the likelihood of use. Colombia set up a public cord blood bank in 2014; and, as a result of its research for improving high total nucleated cell content, a new strategy for UCB collection was developed. Data from 2933 collected and 759 cryopreserved cord blood units between 2014 and 2015 were analyzed. The correlation of donor and collection variables with cellularity was evaluated. Moreover, blood volume, cell content, CD34+ count, clonogenic capacity, and microbial contamination were assessed comparing the new method, which combines in utero and ex utero techniques, with the conventional strategies. Multivariate analysis confirmed a correlation between neonatal birth weight and cell content. The new collection method increased total nucleated cell content in approximately 26% and did not alter pre-cryopreservation and post-thaw cell recovery, viability, or clonogenic ability. Furthermore, it showed a remarkably low microbial contamination rate (1.2%). The strategy for UCB collection developed at the first Colombian public cord blood bank increases total nucleated cell content and does not affect unit quality. The existence of this bank is a remarkable breakthrough for Latin-American patients in need of this kind of transplantation. © 2017 The Authors Transfusion published by Wiley Periodicals, Inc. on behalf of AABB.

  16. A Collaborative Study for the Determination of Tobacco Specific Nitrosamines in Tobacco

    Directory of Open Access Journals (Sweden)

    Morgan WT

    2014-12-01

    Full Text Available The manuscript presents results from a collaborative study by 15 different laboratories using two different methods to determine tobacco specific nitrosamines (TSNAs in tobacco and was performed under the auspices of the Tobacco Science Research Conference Analytical Methods Committee (TSRC-AMC. Although it is apparent that some of the laboratories failed to follow the provided protocols, both methods proved robust for determining TSNAs in a variety of different tobacco types. Twelve laboratories extracted the tobacco sample using an alkaline-methylene chloride extraction (Method 1 and nine used a buffer to extract the tobacco sample (Method 2. Six laboratories performed both methods. All participants used gas chromatography (GC to separate the TSNAs and chemiluminescence detection. Method 1 used N-hexyl-N-nitroso-1-hexanamine (NDHA as a surrogate (added prior to extraction internal standard for quantitation. Method 2 used N-nitrosoguvacoline (NG as the surrogate internal standard, NDHA as a chromatographic (added after extraction, prior to analysis internal standard and external standard quantitation. After demonstrating that the average accuracy of both methods was at least about 92% through recovery studies, eight different tobacco types were analyzed in triplicate by each method. Means, reproducibility (precision between laboratories and repeatability (precision within a laboratory of results were determined for each method. After statistical analyses, it was established that both methods were capable of analyzing a variety of tobacco types and repeatability between methods was not significantly different. The limit of detection (LOD and limit of quantitation (LOQ were lower for Method 2 as compared to Method 1 when using the surrogate internal standard. Reproducibility variation, analyzed as the coefficient of variation, was 6% lower for Method 2 vs. Method 1 for N-nitrosonornicotine (NNN and directionally 12% lower for 4-(methylnitrosamino

  17. A Content Analysis of College Reading Association/Association of Literacy Educators and Researchers Teacher Education Publications: Past, Present, and Future

    Science.gov (United States)

    Schumm, Jeanne Shay; Lewis-Spector, Jill; Price, Debra; Doorn, Kristen

    2014-01-01

    The purpose of this investigation was to conduct a content analysis of the publications of the Association of Literacy Educators and Researchers (ALER), previously known as College Reading Association (CRA), in the area of preservice teacher education in literacy. As a service to the organization, 71 articles published in ALER's flagship…

  18. Genotoxicity of a Low-Dose Nitrosamine Mixture as Drinking Water Disinfection Byproducts in NIH3T3 Cells.

    Science.gov (United States)

    Wang, Hai-Yan; Qin, Ming; Dong, Lei; Lv, Jia-Ying; Wang, Xia

    2017-01-01

    N - nitrosamines (NAms), which can arise as byproducts of disinfection agents, are reportedly found in drinking water, and their potential carcinogenicity is a concern; however, little research exists regarding the genotoxicity or carcinogenicity of NAms exposure as a low-dose mixture. The three most common NAms components in China's drinking water are N -nitrosodimethylamine (NDMA), N -nitrosodiethylamine (NDEA) and N -nitrosomethylethylamine (NMEA). Thus, we measured the genotoxic and carcinogenic potential of these compounds and measured the cell cycle and gene expression. The data show that exposure to the NAms-mixture doubled the revertants in the TA98 and TA100 S. typhimurium strains and increased the DNA double-strand breaks and the micronuclear frequency in the NIH3T3 cells compared to a single exposure. After long-term NAms mixture exposure, a malignant transformation of NIH3T3 and a significantly increased G2/M distribution were observed. Furthermore, P53, CDK1, P38, CDC25A and CyclinB expressions were down-regulated in the NAms-mixture exposure group; however, P21 and GADD45A genes were up-regulated. Interestingly, the CHK1/CHK2 and CDC25A genes had two responses, depending on the NAms concentrations. Thus, we observed mutagenic, genotoxic and carcinogenic effects after a low-dose NAms-mixture exposure in drinking water, and DNA repair and apoptosis pathways may contribute to these adverse effects.

  19. Is Content Really King? An Objective Analysis of the Public's Response to Medical Videos on YouTube

    Science.gov (United States)

    Desai, Tejas; Shariff, Afreen; Dhingra, Vibhu; Minhas, Deeba; Eure, Megan; Kats, Mark

    2013-01-01

    Medical educators and patients are turning to YouTube to teach and learn about medical conditions. These videos are from authors whose credibility cannot be verified & are not peer reviewed. As a result, studies that have analyzed the educational content of YouTube have reported dismal results. These studies have been unable to exclude videos created by questionable sources and for non-educational purposes. We hypothesize that medical education YouTube videos, authored by credible sources, are of high educational value and appropriately suited to educate the public. Credible videos about cardiovascular diseases were identified using the Mayo Clinic's Center for Social Media Health network. Content in each video was assessed by the presence/absence of 7 factors. Each video was also evaluated for understandability using the Suitability Assessment of Materials (SAM). User engagement measurements were obtained for each video. A total of 607 videos (35 hours) were analyzed. Half of all videos contained 3 educational factors: treatment, screening, or prevention. There was no difference between the number of educational factors present & any user engagement measurement (p NS). SAM scores were higher in videos whose content discussed more educational factors (pYouTube. PMID:24367517

  20. The 'Publicness-puzzle' in public leadership. A theoretical exploration of leadership in public organizations

    NARCIS (Netherlands)

    S.J. Dorsman (Stephan); M. Thaens (Marcel); S.M. Groeneveld (Sandra)

    2012-01-01

    textabstractAbstract Following a contingency approach we argue that the content and style of administrative leadership depends on characteristics of the public context. The purpose of the paper is to develop hypotheses on the relationships between several dimensions of publicness and

  1. Evaluation of the Intake of Nitrate, Nitrite, Nitrosodiethylamine and Nitrosodimethylamine by Food Consumption

    Directory of Open Access Journals (Sweden)

    Liliana Avasilcai

    2014-12-01

    Full Text Available The aim of the present study was the evaluation of nitrate, nitrite, nitrosodiethylamine (NDEA and nitrosodimethylamine (NDMA intake by food consumption. We determined concentrations of nitrates, nitrites in 102 food samples (40 meat products, 15 fermented cheese, 25 vegetables, 22 fruits and the concentration NDEA, NDMA in 40 meat products. Nitrates and nitrites were determined using Peter-Griess method; nitrosamines were quantified by HPLC with UV detection.  We designed vegetalian, vegetarian and conventional diets of about 2500 kcal/day.  Based of the values found, we calculated the intake of nitrates, nitrites and nitrosamines. The obtained values fits to WHO’s recommendations, except for vegetalian and conventional diet, in which the nitrate content was 3,46 respectively 1,64 times higher than the acceptable daily intake (157 mg NO3-/day.

  2. The Analysis of Content and Operational Components of Public School Teachers' Continuing Professional Development in Great Britain, Canada and the USA

    Science.gov (United States)

    Mukan, Nataliya; Kravets, Svitlana; Khamulyak, Nataliya

    2016-01-01

    In the article the content and operational components of continuing professional development of public school teachers in Great Britain, Canada, the USA have been characterized. The main objectives are defined as the theoretical analysis of scientific-pedagogical literature, which highlights different aspects of the problem under research;…

  3. Digital Broadband Content: Digital Content Strategies and policies. OECD Digital Economy Papers, No. 119

    Science.gov (United States)

    OECD Publishing (NJ1), 2006

    2006-01-01

    The development of digital content raises new issues as rapid technological developments challenge existing business models and government policies. This OECD study identifies and discusses six groups of business and public policy issues and illustrates these with existing and potential OECD Digital Content Strategies and Policies: (1) Innovation…

  4. Use of Twitter Polls to Determine Public Opinion Regarding Content Presented at a Major National Specialty Society Meeting.

    Science.gov (United States)

    Rosenkrantz, Andrew B; Hawkins, C Matthew

    2017-02-01

    The aim of this study was to evaluate the feasibility of using Twitter polls to assess public opinion regarding session content at a national specialty society meeting. Twitter polls allow users to embed multiple-choice questions within tweets and automatically aggregate responses. Two radiologists attending the 2016 annual meeting of the ACR posted a Twitter poll containing the hashtag #ACR2016 during 10 meeting sessions addressing socioeconomics/advocacy, patient experience, and social media/informatics (20 polls total). Each poll contained a question asking for an opinion regarding the session's content. Polls were open for responses for 24 hours. The average number of responses per poll was significantly higher for the user with the larger number of Twitter followers (24.3 ± 14.4 versus 11.2 ± 9.8, P = .015). A total of 57% of respondents agreed that radiologists' payments should shift to value-based payments, and 86% agreed that radiologists should routinely survey their patients to monitor quality; however, 83% disagreed with basing physician payments on patient satisfaction scores. A total of 85% disagreed that the artificial intelligence supercomputer Watson will entirely replace radiologists. A total of 76% agreed that social media can drive business at less cost than standard marketing. A total of 56% agreed with the direction of the ACR's advocacy and regulatory efforts, whereas 74% considered the ACR's advocacy efforts to be moderately or very useful for their practice. A total of 50% planned to change their practice on the basis of keynote remarks by Dr Ezekiel Emanuel. Twitter polls provide a free and easy infrastructure to potentially capture global public sentiment during the course of a medical society meeting. Their use may enrich and promote discussions of key session content. Copyright © 2016 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  5. Partnering and teamwork to create content for spherical display systems to enhance public literacy in earth system and ocean sciences

    Science.gov (United States)

    Beaulieu, S. E.; Patterson, K.; Joyce, K.; Silva, T.; Madin, K.; Spargo, A.; Brickley, A.; Emery, M.

    2013-12-01

    Spherical display systems, also known as digital globes, are technologies that, in person or online, can be used to help visualize global datasets and earth system processes. Using the InterRidge Global Database of Active Submarine Hydrothermal Vent Fields and imagery from deep-sea vehicles, we are creating content for spherical display systems to educate and excite the public about dynamic geophysical and biological processes and exploration in the deep ocean. The 'Global Viewport for Virtual Exploration of Deep-Sea Hydrothermal Vents' is a collaboration between the Woods Hole Oceanographic Institution and the Ocean Explorium at New Bedford Seaport, hosting a Magic Planet and Science On a Sphere (SOS), respectively. The main activities in the first year of our project were geared towards team building and content development. Here we will highlight the partnering and teamwork involved in creating and testing the effectiveness of our new content. Our core team is composed of a lead scientist, educators at both institutions, graphic artists, and a professional evaluator. The new content addresses key principles of Earth Science Literacy and Ocean Literacy. We will share the collaborative, iterative process by which we developed two educational pieces, 'Life without sunlight' and 'Smoke and fire underwater' - each focusing on a different set of 3 literacy principles. We will share how we conducted our front-end and formative evaluations and how we focused on 2 NSF Informal Education Impact Categories for our evaluation questionnaire for the public. Each educational piece is being produced as a stand-alone movie and as an interactive, docent-led presentation integrating a number of other datasets available from NOAA's SOS Users Network. The proximity of our two institutions enables a unique evaluation of the learning attained with a stand-alone spherical display vs. live presentations with an SOS.

  6. Pins and posters: paradigms for content publication on situated displays

    OpenAIRE

    José, Rui; Pinto, Helder; Siva, Bruno; Melro, Ana

    2013-01-01

    Public display systems are still far from being a communication medium that people can appropriate to serve diverse communication goals. Moving towards open displays will require new publication paradigms that can overcome the challenges of meaningful engagement and enable users to fully understand and control the entire publication process. In this paper, we report on the study of two novel and complimentary communication paradigms for public displays inspired by the metaphors of pin badges ...

  7. Case report combined hepatocellular and cholangiocarcinoma with sarcomatous transformation.

    Science.gov (United States)

    Boonsakan, Paisarn; Thangnapakorn, Orathai; Tapaneeyakorn, Jiemjit; Kositchaiwat, Sawit; Bunyaratvej, Sukhum

    2007-03-01

    Combined hepatocellular and cholangiocarcinoma with sarcomatous transformation was first recognized in Ramathibodi Hospital in 2005. This variant of carcinoma has been increasingly reported particularly from Asian countries. Dedifferentiation of the epithelial component to various sarcomatous components is likely the underlying mechanism. The causative factors of hepatocarcinogenesis in Thailand include chronic viral hepatitis B or C, exposures to aflatoxin B1 and nitrosamine(s) and occasionally some certain nodular hepatocellular lesions due to arterial hyperperfusion. It is suggested that the recent change of the Thai peoples' life style to an increased consumption of fast foods containing food preservatives especially nitrate or nitrite, the nitrosamine precursor may allow heavy exposure(s) to the chemical carcinogen(s) i.e. nitrosamine(s) leading to sarcomatous transformation of the carcinoma.

  8. Implementation of Content and Language Integrated Learning (CLIL) Programmes in Public Administration: Russian Students' and Matriculants' Opinion about Their First CLIL Experience

    Science.gov (United States)

    Rubtcova, Mariia; Kaisarova, Valentina

    2016-01-01

    Content and Language Integrated Learning (CLIL) is a pedagogic approach that has developed in response to the demand for integrating education in both school/university subjects and language skills. Our paper is devoted to the implementation of CLIL programmes in Public Administration within a particular sociolinguistic context: that of Russian…

  9. Public licenses and public domain as alternatives to copyright

    OpenAIRE

    Köppel, Petr

    2012-01-01

    The work first introduces the area of public licenses as a space between the copyright law and public domain. After that, consecutively for proprietary software, free and open source software, open hardware and open content, it maps particular types of public licenses and the accompanying social and cultural movements, puts them in mutual as well as historical context, examines their characteristics and compares them to each other, shows how the public licenses are defined by various accompan...

  10. Open Content in Open Context

    Science.gov (United States)

    Kansa, Sarah Whitcher; Kansa, Eric C.

    2007-01-01

    This article presents the challenges and rewards of sharing research content through a discussion of Open Context, a new open access data publication system for field sciences and museum collections. Open Context is the first data repository of its kind, allowing self-publication of research data, community commentary through tagging, and clear…

  11. Without blinders: Public values scholarship in Political Science, Economics, and Law—content and contribution to Public Administration

    NARCIS (Netherlands)

    de Graaf, Gjalt; van der Wal, Z.

    2017-01-01

    How and why are public values studied within public administration’s cognate disciplines? This question is addressed through a qualitative analysis of 50 public values (PVs) publications in political science, economics, and law published between 1969 and 2014. The findings show that political

  12. Effect of Ozonation and Biological Activated Carbon Treatment of Wastewater Effluents on Formation of N-nitrosamines and Halogenated Disinfection Byproducts.

    Science.gov (United States)

    Chuang, Yi-Hsueh; Mitch, William A

    2017-02-21

    Ozonation followed by biological activated carbon (O 3 /BAC) is being considered as a key component of reverse osmosis-free advanced treatment trains for potable wastewater reuse. Using a laboratory-scale O 3 /BAC system treating two nitrified wastewater effluents, this study characterized the effect of different ozone dosages (0-1.0 mg O 3 /mg dissolved organic carbon) and BAC empty bed contact times (EBCT; 15-60 min) on the formation after chlorination or chloramination of 35 regulated and unregulated halogenated disinfection byproducts (DBPs), 8 N-nitrosamines, and bromate. DBP concentrations were remarkably similar between the two wastewaters across O 3 /BAC conditions. Ozonation increased bromate, TCNM, and N-nitrosodimethylamine, but ozonation was less significant for other DBPs. DBP formation generally decreased significantly with BAC treatment at 15 min EBCT, but little further reduction was observed at higher EBCT where low dissolved oxygen concentrations may have limited biological activity. The O 3 /BAC-treated wastewaters met regulatory levels for trihalomethanes (THMs), haloacetic acids (HAAs), and bromate, although N-nitrosodimethylamine exceeded the California Notification Level in one case. Regulated THMs and HAAs dominated by mass. When DBP concentrations were weighted by measures of their toxic potencies, unregulated haloacetonitriles, haloacetaldehydes, and haloacetamides dominated. Assuming toxicity is additive, the calculated DBP-associated toxicity of the O 3 /BAC-treated chloraminated effluents were comparable or slightly higher than those calculated in a recent evaluation of Full Advanced Treatment trains incorporating reverse osmosis.

  13. The prevalence of harmful content on outdoor advertising in Los Angeles: land use, community characteristics, and the spatial inequality of a public health nuisance.

    Science.gov (United States)

    Lowery, Bryce C; Sloane, David C

    2014-04-01

    Our study sought to examine associations between the content of outdoor advertising and neighborhood ethnic/racial and socioeconomic composition to see whether particular communities disproportionately host harmful content. We constructed a spatial database of photographs taken from June 2012 until December 2012 in 7 identically zoned communities in Los Angeles, California, to compare outdoor advertising area and content. We selected communities to contrast by ethnicity/race, income, education, and youth population. At-risk communities and communities of color hosted more outdoor advertising depicting harmful content than other communities. Among included neighborhoods, harmful content and the proportion of outdoor advertising overall were most prevalent in communities of Asian Americans and Latino Americans. In all communities, harmful content represented at least 24% of outdoor advertising space. This study provides evidence of the potential for land-use decisions to result in spatially inequitable health impacts. Although dictating the placement of outdoor advertising through zoning may seem sensible, such a decision might have the unintended consequence of disadvantaging the well-being of local communities. Neighborhood factors require more contextually nuanced public health and land-use policy.

  14. 36 CFR 294.14 - Petition contents.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Petition contents. 294.14... State Petitions for Inventoried Roadless Area Management § 294.14 Petition contents. (a) Any petition... particular lands for which the petition is being made, including maps and other appropriate resources in...

  15. Identifying the Gender Dimension in Research Content

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, D.; Lalonde, B.St.L.; Tippett, C.; Archambault, E.; Callaert, J.; Mantouvalou, K.; Arora, L.

    2016-07-01

    Globally, there is an increasing interest in integrating the gender dimension in research content (GDRC). As a first step towards monitoring progress in this area, a new indicator measuring the proportion of a country’s scientific publications integrating a gender dimension in their subject matter was developed for the European Commission’s She Figures 2015 publication. This indicator is based on a keyword-based query covering both sex-related terms (biological characteristics of both women and men) and gender-related terms (social/cultural factors of both women and men). The final GDRC dataset consisted of some 212,600 distinct publications including a gender dimension in their research content. Findings suggest that integrating a gender dimension into research content is relatively rare. Unsurprisingly, it was less common for scientific articles in the fields of agricultural sciences, engineering and technology, and natural sciences to do so, and more common in the social sciences. (Author)

  16. Atmospheric chemistry and environmental impact of the use of amines in carbon capture and storage (CCS).

    Science.gov (United States)

    Nielsen, Claus J; Herrmann, Hartmut; Weller, Christian

    2012-10-07

    This critical review addresses the atmospheric gas phase and aqueous phase amine chemistry that is relevant to potential emissions from amine-based carbon capture and storage (CCS). The focus is on amine, nitrosamine and nitramine degradation, and nitrosamine and nitramine formation processes. A comparison between the relative importance of the various atmospheric sinks for amines, nitrosamines and nitramines is presented.

  17. 42 CFR 456.243 - Content of medical care evaluation studies.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Content of medical care evaluation studies. 456.243 Section 456.243 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Ur Plan: Medical Care Evaluation Studies § 456.243 Content of medical care evaluation studies. Each...

  18. 42 CFR 456.143 - Content of medical care evaluation studies.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Content of medical care evaluation studies. 456.143 Section 456.143 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN...: Medical Care Evaluation Studies § 456.143 Content of medical care evaluation studies. Each medical care...

  19. 46 CFR 531.9 - Publication.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Publication. 531.9 Section 531.9 Shipping FEDERAL... Publication of Essential Terms § 531.9 Publication. (a) Contents. All authorized persons who choose to file... contained in a publication widely available to the public and well known within the industry. Reference may...

  20. Unprofessional content on Facebook accounts of US urology residency graduates.

    Science.gov (United States)

    Koo, Kevin; Ficko, Zita; Gormley, E Ann

    2017-06-01

    To characterize unprofessional content on public Facebook accounts of contemporary US urology residency graduates. Facebook was queried with the names of all urologists who graduated from US urology residency programmes in 2015 to identify publicly accessible profiles. Profiles were assessed for unprofessional or potentially objectionable content using a prospectively designed rubric, based on professionalism guidelines by the American Urological Association, the American Medical Association, and the Accreditation Council for Graduate Medical Education. Content authorship (self vs other) was determined, and profiles were reviewed for self-identification as a urologist. Of 281 graduates, 223 (79%) were men and 267 (95%) held MD degrees. A total of 201 graduates (72%) had publicly identifiable Facebook profiles. Of these, 80 profiles (40%) included unprofessional or potentially objectionable content, including 27 profiles (13%) reflecting explicitly unprofessional behaviour, such as depictions of intoxication, uncensored profanity, unlawful behaviour, and confidential patient information. When unprofessional content was found, the content was self-authored in 82% of categories. Among 85 graduates (42%) who self-identified as a urologist on social media, nearly half contained concerning content. No differences in content were found between men and women, MD and DO degree-holders, or those who did or did not identify as a urologist (all P > 0.05). The majority of recent residency graduates had publicly accessible Facebook profiles, and a substantial proportion contained self-authored unprofessional content. Of those identifying as urologists on Facebook, approximately half violated published professionalism guidelines. Greater awareness of trainees' online identities is needed. © 2017 The Authors BJU International © 2017 BJU International Published by John Wiley & Sons Ltd.

  1. The Prevalence of Harmful Content on Outdoor Advertising in Los Angeles: Land Use, Community Characteristics, and the Spatial Inequality of a Public Health Nuisance

    Science.gov (United States)

    Sloane, David C.

    2014-01-01

    Objectives. Our study sought to examine associations between the content of outdoor advertising and neighborhood ethnic/racial and socioeconomic composition to see whether particular communities disproportionately host harmful content. Methods. We constructed a spatial database of photographs taken from June 2012 until December 2012 in 7 identically zoned communities in Los Angeles, California, to compare outdoor advertising area and content. We selected communities to contrast by ethnicity/race, income, education, and youth population. Results. At-risk communities and communities of color hosted more outdoor advertising depicting harmful content than other communities. Among included neighborhoods, harmful content and the proportion of outdoor advertising overall were most prevalent in communities of Asian Americans and Latino Americans. In all communities, harmful content represented at least 24% of outdoor advertising space. Conclusions. This study provides evidence of the potential for land-use decisions to result in spatially inequitable health impacts. Although dictating the placement of outdoor advertising through zoning may seem sensible, such a decision might have the unintended consequence of disadvantaging the well-being of local communities. Neighborhood factors require more contextually nuanced public health and land-use policy. PMID:24524512

  2. 36 CFR 223.82 - Contents of advertisement.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Contents of advertisement... SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER Timber Sale Contracts Advertisement and Bids § 223.82 Contents of advertisement. (a) A timber sale advertisement shall include the following information...

  3. 36 CFR 223.228 - Contents of advertisement.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Contents of advertisement... SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER Special Forest Products Advertisement and Bids § 223.228 Contents of advertisement. The Forest Service shall include the following information in an...

  4. Cobra: A content-based video retrieval system

    NARCIS (Netherlands)

    Petkovic, M.; Jonker, W.; Jensen, C.S.; Jeffery, K.G.; Pokorny, J.; Saltenis, S.; Bertino, E.; Böhm, K.; Jarke, M.

    2002-01-01

    An increasing number of large publicly available video libraries results in a demand for techniques that can manipulate the video data based on content. In this paper, we present a content-based video retrieval system called Cobra. The system supports automatic extraction and retrieval of high-level

  5. The legitimacy of area-based restrictions to maintain public order: giving content to the proportionality principle from a European legal perspective

    OpenAIRE

    Todts, Liesbeth

    2017-01-01

    Abstract: This contribution aims to provide a first exploratory analysis of the criteria that must be taken into account by national authorities when considering the proportionality of public order measures restricting the individual's fundamental right to freedom of movement, such as area-based restrictions. The content of the proportionality principle as regards area-based restrictions is not always clear, in particular at European human rights level, while it is an important condition that...

  6. Formation and Control of N-Nitrosodimethylamine (NDMA) in Wastewater Reclaimed for Indirect Potable Reuse

    OpenAIRE

    Sgroi, Massimiliano

    2014-01-01

    A large variety of disinfection by-products (DBPs) are formed during water treatment processes using chlorination. Disinfection with chloramines is often used to significantly reduce the formation of regulated DBPs. However, chloramination favours the formation of N-nitrosamines, which are emerging by-products of health concern. Of all the nitrosamines, N-nitrosodimethylamine (NDMA) has been most commonly detected in drinking water and wastewater. Nitrosamines can also be produced using diffe...

  7. Analysis of Aqueous Extractable Protein in Radiation Pre vulcanized Natural Rubber Latex (RVNRL) And Sulphur Pre vulcanized Natural Rubber Latex (SVNRL)

    International Nuclear Information System (INIS)

    Sofian Ibrahim; Mohd Noor Wadi Mat Lazim; Syuhada Ramli; Keong, C.C.; Khairul Hisyam Mohd Yusof; Muhammad Saiful Omar; Najib Mohd Zakey; Hafizuddin Maseri; Noor Hasni Mohd Ali

    2015-01-01

    The use of radiation do not only produces Radiation Pre vulcanized Natural Rubber Latex (RVNRL) that can be used for the production of nitrosamines free products, moreover, RVNRL also able to exclude type IV allergy that caused by high protein content in the products. Leaching water from production of finger coat from RVNRL and Sulphur Pre vulcanized Natural rubber Latex (SVNRL) has been collected. Extractable protein content from water samples measured according to the test protocol ASTM D5712-2010. Water from leaching process of finger coat made from RVNRL showed a higher protein content than SVNRL. This explains why RVNRL based products contain very low protein content and thus reduce the risk of Type IV allergy. (author)

  8. Content and Citation Analyses of "Public Relations Review."

    Science.gov (United States)

    Morton, Linda P.; Lin, Li-Yun

    1995-01-01

    Analyzes 161 cited and 177 uncited articles published in "Public Relations Review" (1975-93) to determine if 3 independent variables--research methods, type of statistics, and topics--influenced whether or not articles were cited in other research articles. Finds significant differences between quantitative and qualitative research methods but not…

  9. Developing an evidence-based public health informatics course.

    Science.gov (United States)

    Yu, Xinyu; Xie, Yue; Pan, Xuequn; Mayfield-Johnson, Susan; Whipple, Jessica; Azadbakht, Elena

    2015-10-01

    This study assessed the need to develop a public health informatics (PHI) introductory course and determine contents of such a course. Community assessments employing focus group interviews and an online survey were utilized to determine course need and content. Results revealed a need to provide PHI training to graduate public health students and suggested broad course content requirements. Results indicated lack of awareness of libraries and librarians as sources of public health information. A graduate PHI course was developed and delivered. Additionally, implementation of a subject guide increased the library's profile.

  10. 76 FR 68518 - Request for Information: Public Access to Peer-Reviewed Scholarly Publications Resulting From...

    Science.gov (United States)

    2011-11-04

    ... archiving publications and making them publically accessible be used to grow the economy and improve the... can ensure long-term stewardship if content is distributed across multiple private sources? (4) Are...

  11. 76 FR 80418 - Request for Information: Public Access to Peer-Reviewed Scholarly Publications Resulting From...

    Science.gov (United States)

    2011-12-23

    ... archiving publications and making them publically accessible be used to grow the economy and improve the... can ensure long-term stewardship if content is distributed across multiple private sources? (4) Are...

  12. 46 CFR 530.12 - Publication.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Publication. 530.12 Section 530.12 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE SERVICE CONTRACTS Publication of Essential Terms § 530.12 Publication. (a) Contents. All authorized persons who have a duty to file...

  13. User innovation in public service broadcasts

    DEFF Research Database (Denmark)

    Khajeheian, Datis; Tadayoni, Reza

    2016-01-01

    and develop user innovations into professional content. This study follows a qualitative approach with a document study of Denmark's public service broadcast and two interviews. Findings indicate that the commitment to quality and professional content prevents managers of PSBs from outsourcing......This research aims to understand how public service media can encourage media entrepreneurship in the society to enrich user innovations as a source of ideas, products, contents, talent and creativity. The assumption is that media entrepreneurs turn users into sources of external creativity...... their production to media entrepreneurs, but they trust large media companies as external producers. This research contributes to the field by proposing that public service media can foster media entrepreneurship in a society indirectly and by creating demand for external sources of creativity. Large media...

  14. 15 CFR 930.61 - Public participation.

    Science.gov (United States)

    2010-01-01

    ... comments, hearing proceedings and final decision-making to the minimum time necessary to reasonably inform the public, obtain sufficient comment, and develop a decision on the matter. (b) Content of public... for issuance of public notice include, but are not limited to, public notice through an official State...

  15. 43 CFR 4.1292 - Contents of petition.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Contents of petition. 4.1292 Section 4... PROCEDURES Special Rules Applicable to Surface Coal Mining Hearings and Appeals Petitions for Award of Costs and Expenses Under Section 525(e) of the Act § 4.1292 Contents of petition. (a) A petition filed under...

  16. Content analysis of publications on product-service systems

    Directory of Open Access Journals (Sweden)

    Fernanda Hänsch Beuren

    2014-02-01

    Full Text Available This work is an update of the literature on product-service systems (PSS through a review of the literature from 2006 to 2011. Aiming at changing consumption of products to a more sustainable society, the PSS has been considered a competitive opportunity, which offers the use of the product through the provision of services. In this context, this paper aims to complement the existing literature on PSS through a structured search of relevant journal databases. The identified studies have important information on the PSS and these are presented throughout the text, highlighting major journals, most cited authors and the main article used as reference by the academy. From the identified and interpreted publications, the paper highlights some key factors, which the literature has approached on the subject in recent years. Therefore, by analyzing the publications during the selected study period, a conclusive synthesis is presented at the end of each key-factor. Finally, some suggestions for future research on the subject are presented, highlighting the need for theoretical and empirical research to achieve better understanding about the benefits of a PSS as well as tools and methodologies that facilitate its implementation.

  17. NIGERIAN VETERINARY JOURNAL

    African Journals Online (AJOL)

    ADEYEYE

    cigarettes, cosmetics, condoms, party balloons and other rubber ..... determine levels of nitrosamines, nitrates and nitrites entails the use of High performance liquid chromatography ... might lead to the secretion of nitrosamines into eggs.

  18. Stopping Web Plagiarists from Stealing Your Content

    Science.gov (United States)

    Goldsborough, Reid

    2004-01-01

    This article gives tips on how to avoid having content stolen by plagiarists. Suggestions include: using a Web search service such as Google to search for unique strings of text at the individuals site to uncover other sites with the same content; buying a infringement-detection program; or hiring a public relations firm to do the work. There are…

  19. Online Education in Public Affairs

    Science.gov (United States)

    Ginn, Martha H.; Hammond, Augustine

    2012-01-01

    This exploratory study provides an overview of the current landscape of online education in the fields of Master of Public Administration and Master of Public Policy (MPA/MPP) utilizing a dataset compiled from content analysis of MPA/MPP programs' websites and survey of 96 National Association of Schools of Public Affairs and Administration…

  20. Determination of N-nitrosamines in processed meats by liquid extraction combined with gas chromatography-methanol chemical ionisation/mass spectrometry.

    Science.gov (United States)

    Scheeren, Marina Bergoli; Sabik, Hassan; Gariépy, Claude; Terra, Nelcindo Nascimento; Arul, Joseph

    2015-01-01

    A simple, accessible and reproducible method was developed and validated as an alternative for the determination of nine volatile N-nitrosamines (NAs) in meat products, using a low volume of organic solvent and without requiring specific apparatus, offering the possibility of practical implementation in routine laboratories. The NAs were extracted with dichloromethane followed by a clean-up with phosphate buffer solution (pH 7.0). The extracts were analysed by gas chromatography-chemical ionisation/mass spectrometry (GC-CI/MS) in positive-ion mode using methanol as reagent. Limits of detection and quantification, recovery and reproducibility were determined for all NAs (N-nitrosodimethylamine, N-nitrosomethylethylamine, N-nitrosodiethylamine, N-nitrosopyrrolidine, N-nitrosodipropylamine, N-nitrosomorpholine, N-nitrosopiperidine, N-nitrosodibutylamine and N-nitrosodiphenylamine). Satisfactory sensitivity and selectivity were obtained even without concentrating the extract by solvent evaporation, avoiding the loss of the nine NAs studied. Limits of detection ranged from 0.15 to 0.37 µg kg(-1), whereas limits of quantification ranged from 0.50 to 1.24 µg kg(-1). Recoveries calculated in cooked ham that had been spiked at 10 and 100 µg kg(-1) were found to be between 70% and 114% with an average relative standard deviation of 13.2%. The method was successfully used to analyse five samples of processed meat products on the day of purchase and 7 days later (after storage at 4°C). The most abundant NAs found in the analysed products were N-nitrosodipropylamine and N-nitrosopiperidine, which ranged from 1.75 to 34.75 µg kg(-1) and from 1.50 to 4.26 µg kg(-1), respectively. In general, an increase in the level of NAs was observed after the storage period. The proposed method may therefore be a useful tool for food safety control once it allows assessing the profile and the dietary intake of NAs in food over time.

  1. Analyzing Public Discourse: Using Media Content Analysis to Understand the Policy Process

    Science.gov (United States)

    Saraisky, Nancy Green

    2016-01-01

    One of the most basic and obvious sources of data for education policy analysis is text. This article discusses content analysis as an important part of the methodological toolbox for elucidating patterns and trends about education policy. Focusing specifically on media, I show how media content analysis can produce nuanced insights about the ways…

  2. Public Information for Water Pollution Control.

    Science.gov (United States)

    Water Pollution Control Federation, Washington, DC.

    This publication is a handbook for water pollution control personnel to guide them towards a successful public relations program. This handbook was written to incorporate the latest methods of teaching basic public information techniques to the non-professional in this area. Contents include: (1) a rationale for a public information program; (2)…

  3. Resources for Public Relations Teaching: Facilitating the Growth of Public Relations Education.

    Science.gov (United States)

    Coombs, Timothy

    2001-01-01

    Discusses briefly events (including a 1998 summer conference, a report, and a 1999 Pre-Conference) leading up to this themed issue on public relations teaching. Introduces the seven remaining articles in the issue which represent six different content areas to be covered in a public relations curriculum, and which reflects recommendations for…

  4. Delay-sensitive content distribution via peer-to-peer collaboration in public safety vehicular ad-hoc networks

    KAUST Repository

    Atat, Rachad; Yaacoub, Elias E.; Alouini, Mohamed-Slim; Filali, Fethi; Abu-Dayya, Adnan A.

    2014-01-01

    Delay-sensitive content distribution with peer-to-peer (P2P) cooperation in public safety vehicular networks is investigated. Two cooperative schemes are presented and analyzed. The first scheme is based on unicasting from the base station, whereas the second is based on threshold based multicasting. Long Term Evolution (LTE) is used for long range (LR) communications with the base station (BS) and IEEE 802.11p is considered for inter-vehicle collaboration on the short range (SR). The first scheme is shown to outperform non-cooperative unicasting and multicasting, while the second scheme outperforms non-cooperative unicasting beyond a specific number of cooperating vehicles, when the appropriate 802.11p power class is used. The first scheme achieves the best performance among the compared methods, and a practical approximation of that scheme is shown to be close to optimal performance. © 2014 Elsevier B.V. All rights reserved.

  5. Delay-sensitive content distribution via peer-to-peer collaboration in public safety vehicular ad-hoc networks

    KAUST Repository

    Atat, Rachad

    2014-05-01

    Delay-sensitive content distribution with peer-to-peer (P2P) cooperation in public safety vehicular networks is investigated. Two cooperative schemes are presented and analyzed. The first scheme is based on unicasting from the base station, whereas the second is based on threshold based multicasting. Long Term Evolution (LTE) is used for long range (LR) communications with the base station (BS) and IEEE 802.11p is considered for inter-vehicle collaboration on the short range (SR). The first scheme is shown to outperform non-cooperative unicasting and multicasting, while the second scheme outperforms non-cooperative unicasting beyond a specific number of cooperating vehicles, when the appropriate 802.11p power class is used. The first scheme achieves the best performance among the compared methods, and a practical approximation of that scheme is shown to be close to optimal performance. © 2014 Elsevier B.V. All rights reserved.

  6. Climate Change Discourse in Mass Media: Application of Computer-Assisted Content Analysis

    Science.gov (United States)

    Kirilenko, Andrei P.; Stepchenkova, Svetlana O.

    2012-01-01

    Content analysis of mass media publications has become a major scientific method used to analyze public discourse on climate change. We propose a computer-assisted content analysis method to extract prevalent themes and analyze discourse changes over an extended period in an objective and quantifiable manner. The method includes the following: (1)…

  7. Assessing Youth-Appealing Content in Alcohol Advertisements: Application of a Content Appealing to Youth (CAY) Index.

    Science.gov (United States)

    Padon, Alisa A; Rimal, Rajiv N; DeJong, William; Siegel, Michael; Jernigan, David

    2018-02-01

    Underage drinking is a serious public health problem in the United States, and youth exposure to alcohol advertising has been indicated as a possible contributing factor. Although a number of studies have identified advertising content features that youth find appealing, a key limitation of this research is the absence of a broader tool to examine those features, especially those used by alcohol brands that are popular with underage drinkers. We created an index of content elements found in the research literature to be appealing to youth, and then used this index in a content analysis to identify the degree to which youth-appealing content appeared in a sample of alcohol ads that aired on television shows popular among youth. Finally, using bivariate analysis, we tested the relationship between alcohol brands' use of this content and the popularity of those brands among youth. We found that many of the ads featured youth-appealing content, and that the ads for the alcohol brands most popular among youth had more youth-appealing content than the less popular brands.

  8. Constructing public worlds

    DEFF Research Database (Denmark)

    Jovchelovitch, Sandra; Priego-Hernandez, Jacqueline; Glaveanu, Vlad Petre

    2013-01-01

    : This paper explores how children in different cultures and socio-economic contexts develop representations about the public sphere. It addresses how contexts of representation shape the form and content of children’s thinking while expressing the two-way transactions between the child...... world. In affluent or individualistic public spheres we recognise the classical developmental pathway proposed by Piaget, with a clear increase in the separation between self and society as children grow. Children’s representations are flexible semiotic systems whose form and content interact...... productively with the context in which they develop. These results reject conceptions of children’s knowledge as a prototype of adult knowledge, suggesting that children’s societal knowledge evolves through adaptive strategies to specific socio-cultural environments....

  9. PRESENCE OF NITRATES AND NITRITES IN WATER FOR HUMAN CONSUMPTION AND THEIR IMPACT ON PUBLIC HEALTH IN SUGARCANE-PRODUCING AREAS

    OpenAIRE

    Itzel Galaviz-Villa; Cesáreo Landeros-Sánchez; Ma. del Refugio Castañeda Chávez; Fabiola Lango-Reynoso; Juan Pablo Martínez-Dávila; Arturo Pérez-Vázquez; Iourii Nikolskii-Gavrilov

    2011-01-01

    Water pollution has emerged as a consequence of human settlements, as well as from specific rural, agricultural, forestry and industrial activities within a region. It has been found that increasing use of nitrogen fertilizers also increases water pollution. Nitrates and nitrites that are dissolved in groundwater used for human consumption cause adverse health effects, such as production of nitrosamines (cause of cancer) and decrease of oxygen carrying capacity of the blood, known as blue bab...

  10. Monitoring the Sodium Content of Restaurant Foods: Public Health Challenges and Opportunities

    Science.gov (United States)

    Cogswell, Mary E.; Gunn, Janelle P.; Curtis, Christine J.; Rhodes, Donna; Hoy, Kathy; Pehrsson, Pamela; Nickle, Melissa; Merritt, Robert

    2013-01-01

    We reviewed methods of studies assessing restaurant foods’ sodium content and nutrition databases. We systematically searched the 1964–2012 literature and manually examined references in selected articles and studies. Twenty-six (5.2%) of the 499 articles we found met the inclusion criteria and were abstracted. Five were conducted nationally. Sodium content determination methods included laboratory analysis (n = 15), point-of-purchase nutrition information or restaurants’ Web sites (n = 8), and menu analysis with a nutrient database (n = 3). There is no comprehensive data system that provides all information needed to monitor changes in sodium or other nutrients among restaurant foods. Combining information from different sources and methods may help inform a comprehensive system to monitor sodium content reduction efforts in the US food supply and to develop future strategies. PMID:23865701

  11. Proceedings of the Annual Conference on Environmental Toxicology (7th) 13, 14 and 15 October 1976

    Science.gov (United States)

    1977-04-01

    Nitrosopiperidine 0 - 9 ng Unknown unsymmetrical nitrosamines + II. Lung Polonium - 210 0.03-1.3 pCi + Nickel compounds 0 - 600 ng + Cadmium 9 - 70 ng...industrial development. In support of this under- standing, scientific papers, as well as reports in the public press, indicate that a number of food ...Mabuchi, 1972; Fraumeni, 1975). Ac- cording to current ideas, these causal factors are basically unre- lated to food additives, insecticides, pesticides

  12. Database Support for Research in Public Administration

    Science.gov (United States)

    Tucker, James Cory

    2005-01-01

    This study examines the extent to which databases support student and faculty research in the area of public administration. A list of journals in public administration, public policy, political science, public budgeting and finance, and other related areas was compared to the journal content list of six business databases. These databases…

  13. 43 CFR 46.310 - Contents of an environmental assessment.

    Science.gov (United States)

    2010-10-01

    ... implementation without the need for further analysis. Adaptive management includes a monitoring component... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Contents of an environmental assessment... OF THE NATIONAL ENVIRONMENTAL POLICY ACT OF 1969 Environmental Assessments § 46.310 Contents of an...

  14. Effect of Dry Red Grape Pomace as a Nitrite Substitute on the Microbiological and Physicochemical Properties and Residual Nitrite of Dry-cured Sausage

    OpenAIRE

    Fatemeh Riazi; Fariba Zeynali; Ebrahim Hoseini; Homa Behmadi

    2016-01-01

    Background and Objectives: Sodium nitrite and potassium nitrite have been traditionally used for inhibition of Clostridium botulinum and also as an agent to stabilize the color of meat products; however, usage of these additives at high levels could lead to toxicity and cancer originating from the formation of nitrosamines. Nowadays, application of natural preservatives in order to reduce the nitrite content in meat products is increasing. Thus, we used dry red grape pomace (DRGP) as a natura...

  15. Public programming in the archival literature: revelations from a ...

    African Journals Online (AJOL)

    Public programming in the archival literature: revelations from a content ... of archivists, outreach programmes, publicity, social media, and public relations. Information and communication technologies (ICTs) may play a greater role in public ...

  16. Validity and Reliability of Malay Version of the Job Content Questionnaire among Public Hospital Female Nurses in Malaysia

    Directory of Open Access Journals (Sweden)

    NA Amin

    2015-10-01

    Full Text Available Background: The Job Content Questionnaire (M-JCQ is an established self-reported instrument used across the world to measure the work dimensions based on the Karasek's demand-control-support model. Objective: To evaluate the psychometrics properties of the Malay version of M-JCQ among nurses in Malaysia. Methods: This cross-sectional study was carried out on nurses working in 4 public hospitals in Klang Valley area, Malaysia. M-JCQ was used to assess the perceived psychosocial stressors and physical demands of nurses at their workplaces. Construct validity of the questionnaire was examined using exploratory factor analysis (EFA. Cronbach's α values were used to estimate the reliability (internal consistency of the M-JCQ. Results: EFA showed that 34 selected items were loaded in 4 factors. Except for psychological job demand (Cronbach's α 0.51, the remaining 3 α values for 3 subscales (job control, social support, and physical demand were greater than 0.70, indicating acceptable internal consistency. However, an item was excluded due to poor item-total correlation (r<0.3. The final M-JCQ was consisted of 33 items. Conclusion: The M-JCQ is a reliable and valid instrument to measure psychosocial and physical stressors in the workplace of public hospital nurses in Malaysia.

  17. Characteristics of scientific web publications

    DEFF Research Database (Denmark)

    Thorlund Jepsen, Erik; Seiden, Piet; Ingwersen, Peter Emil Rerup

    2004-01-01

    were generated based on specifically selected domain topics that are searched for in three publicly accessible search engines (Google, AllTheWeb, and AltaVista). A sample of the retrieved hits was analyzed with regard to how various publication attributes correlated with the scientific quality...... of the content and whether this information could be employed to harvest, filter, and rank Web publications. The attributes analyzed were inlinks, outlinks, bibliographic references, file format, language, search engine overlap, structural position (according to site structure), and the occurrence of various...... types of metadata. As could be expected, the ranked output differs between the three search engines. Apparently, this is caused by differences in ranking algorithms rather than the databases themselves. In fact, because scientific Web content in this subject domain receives few inlinks, both Alta...

  18. High Ethanol Contents of Spirit Drinks in Kibera Slums, Kenya: Implications for Public Health.

    Science.gov (United States)

    Okaru, Alex O; Abuga, Kennedy O; Kibwage, Isaac O; Lachenmeier, Dirk W

    2017-10-17

    Cheap licit and artisanal illicit spirit drinks have been associated with numerous outbreaks of alcohol poisoning especially with methanol. This study aimed to evaluate the quality of cheap spirit drinks in Kibera slums in Nairobi County, Kenya. The samples consisted of cheap licit spirits ( n = 11) and the artisanal spirit drink, ' chang'aa' , ( n = 28). The parameters of alcoholic strength and volatile composition were used as indicators of quality and were determined using gas chromatography with flame ionization detection (GC-FID) and gas chromatography-mass spectrometry (GC-MS) respectively. The ranges for alcoholic strength were 42.8-85.8% vol and 28.3-56.7% vol for chang'aa and licit spirit drinks respectively, while the pH ranges were 3.3-4.2 and 4.4-4.8 for chang'aa and licit spirit drinks respectively. The majority of volatiles were found in artisanal spirits and they included higher alcohols, ethyl esters and carbonyl compounds. The alcoholic strength of all the artisanal spirits (100%) and 91% of the licit spirits was above the 40% vol of standard spirits such as vodka. The high ethanol content of the alcohol products was the only element of public health significance in this study.

  19. High Ethanol Contents of Spirit Drinks in Kibera Slums, Kenya: Implications for Public Health

    Directory of Open Access Journals (Sweden)

    Alex O. Okaru

    2017-10-01

    Full Text Available Cheap licit and artisanal illicit spirit drinks have been associated with numerous outbreaks of alcohol poisoning especially with methanol. This study aimed to evaluate the quality of cheap spirit drinks in Kibera slums in Nairobi County, Kenya. The samples consisted of cheap licit spirits (n = 11 and the artisanal spirit drink, ‘chang’aa’, (n = 28. The parameters of alcoholic strength and volatile composition were used as indicators of quality and were determined using gas chromatography with flame ionization detection (GC-FID and gas chromatography-mass spectrometry (GC-MS respectively. The ranges for alcoholic strength were 42.8–85.8% vol and 28.3–56.7% vol for chang’aa and licit spirit drinks respectively, while the pH ranges were 3.3–4.2 and 4.4–4.8 for chang’aa and licit spirit drinks respectively. The majority of volatiles were found in artisanal spirits and they included higher alcohols, ethyl esters and carbonyl compounds. The alcoholic strength of all the artisanal spirits (100% and 91% of the licit spirits was above the 40% vol of standard spirits such as vodka. The high ethanol content of the alcohol products was the only element of public health significance in this study.

  20. Language Learning of Gifted Individuals: A Content Analysis Study

    Directory of Open Access Journals (Sweden)

    Beria Gokaydin

    2017-11-01

    Full Text Available This study aims to carry out a content analysis of the studies on language learning of gifted individuals and determine the trends in this field. Articles on language learning of gifted individuals published in the Scopus database were examined based on certain criteria including type of publication, year of publication, language, research discipline, countries of research, institutions of authors, key words, and resources. Data were analyzed with the content analysis method. Results showed that the number of studies on language learning of gifted individuals has increased throughout the years. Recommendations for further research and practices are provided.

  1. Emerging and continuing trends in vaccine opposition website content.

    Science.gov (United States)

    Bean, Sandra J

    2011-02-24

    Anti-vaccination websites appeal to persons searching the Internet for vaccine information that reinforces their predilection to avoid vaccination for themselves or their children. Few published studies have systematically examined these sites. The aim of this study was to employ content analysis as a useful tool for examining and comparing anti-vaccination websites for recurring and changing emphases in content, design, and credibility themes since earlier anti-vaccination website content analyses were conducted. Between February and May 2010, using a commonly available search engine followed by a deep web search, 25 websites that contained anti-vaccination content were reviewed and analyzed for 24 content, 14 design, and 13 credibility attributes. Although several content claims remained similar to earlier analyses, two new themes emerged: (1) the 2009 H1N1 epidemic threat was "manufactured," and (2) the increasing presence of so-called "expert" testimony in opposing vaccination. Anti-vaccination websites are constantly changing in response to the trends in public health and the success of vaccination. Monitoring the changes can permit public health workers to mount programs more quickly to counter the opposition arguments. Additionally, opposition claims commonly appeal to emotions whereas the supporting claims appeal to reason. Effective vaccine support may be better served by including more emotionally compelling content. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. 32 East and Central African Journal of Pharmaceutical Sciences Vol ...

    African Journals Online (AJOL)

    admin

    pyrrolizidine alkaloids, nitrosamines and tannins. Nitrites commonly distributed in plants can easily be converted to nitrosamines. These substances have been found in beers and other plant derived beverages. Some unidentified chemicals in smoke from firewood commonly used by rural people are implicated in.

  3. Applying polarity rapid assessment method and ultrafiltration to characterize NDMA precursors in wastewater effluents.

    Science.gov (United States)

    Chen, Chao; Leavey, Shannon; Krasner, Stuart W; Mel Suffet, I H

    2014-06-15

    Certain nitrosamines in water are disinfection byproducts that are probable human carcinogens. Nitrosamines have diverse and complex precursors that include effluent organic matter, some anthropogenic chemicals, and natural (likely non-humic) substances. An easy and selective tool was first developed to characterize nitrosamine precursors in treated wastewaters, including different process effluents. This tool takes advantages of the polarity rapid assessment method (PRAM) and ultrafiltration (UF) (molecular weight distribution) to locate the fractions with the strongest contributions to the nitrosamine precursor pool in the effluent organic matter. Strong cation exchange (SCX) and C18 solid-phase extraction cartridges were used for their high selectivity for nitrosamine precursors. The details of PRAM operation, such as cartridge clean-up, capacity, pH influence, and quality control were included in this paper, as well as the main parameters of UF operation. Preliminary testing of the PRAM/UF method with effluents from one wastewater treatment plant gave very informative results. SCX retained 45-90% of the N-nitrosodimethylamine (NDMA) formation potential (FP)-a measure of the precursors-in secondary and tertiary wastewater effluents. These results are consistent with NDMA precursors likely having a positively charged amine group. C18 adsorbed 30-45% of the NDMAFP, which indicates that a substantial portion of these precursors were non-polar. The small molecular weight (MW) (10 kDa) fractions obtained from UF were the primary contributors to NDMAFP. The combination of PRAM and UF brings important information on the characteristics of nitrosamine precursors in water with easy operation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Content Analysis of Tobacco-related Twitter Posts

    OpenAIRE

    Mysl?n, Mark; Zhu, Shu-Hong; Conway, Michael

    2013-01-01

    Objective We present results of a content analysis of tobacco-related Twitter posts (tweets), focusing on tweets referencing e-cigarettes and hookah. Introduction Vast amounts of free, real-time, localizable Twitter data offer new possibilities for public health workers to identify trends and attitudes that more traditional surveillance methods may not capture, particularly in emerging areas of public health concern where reliable statistical evidence is not readily accessible. Existing appli...

  5. Publications | Page 316 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 3151 - 3160 of 6374 ... Through books, articles, research publications, and studies, we aim to widen the impact of our investment and advance development research. ... in tertiary education, Educational Contents of Compulsory ICT Training in Tertiary Education of Mongolia and Evaluation ON ICT education contents.

  6. Tests to evaluate public health disease reporting systems in local public health agencies

    National Research Council Canada - National Science Library

    Dausey, David J

    2005-01-01

    ... to evaluate the ability to receive and respond to case reports 24 hours a day, 7 days a week. We refined these tests by beta-testing them at 20 metropolitan area local public health agencies across the country over the course of 10 months. The contents of this manual will be of interest to public health professionals at the state and local l...

  7. Nuclear public information activities in Chile

    International Nuclear Information System (INIS)

    Munoz Quintana; R

    1995-01-01

    Nuclear plans and developing programs in developing and developed countries are facing-in a higher or lower degree- opposition from public opinion. The objectives and contents of the public education program on nuclear energy in Chile are dealt with in this paper

  8. THE PROBLEM OF CREATION AND CONSUMING OF MEDIA CONTENT OF INNOVATIVE PR

    Directory of Open Access Journals (Sweden)

    Berezenko Vita Vitalyevna

    2013-04-01

    Full Text Available The article analyses on the theoretical level the media content of innovative public relations which can be conveyed via the possibilities of online communication; it also defines the characteristic features of the media content drawing attention of scientific community ( scholars. The purpose of this article - review of the production and consumption of media content of innovative PR in Ukraine at the theoretical level. Problems of creating and consuming of innovative PR media content are determined; among them the problem of professional training and state of being ready of all participants of communication for adequate perception and consuming of innovative media content, intellectual product, as soon as they are science consuming a priori, i.e. complex; the problem of copyright for intellectual product created by both producer and consumer, i.e. created by their mutual efforts. Public relations produce new characteristics of content in media while carrying out strategic functions in the Ukrainian society.

  9. 42 CFR 456.522 - Content of request for variance.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Content of request for variance. 456.522 Section 456.522 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... perform UR within the time requirements for which the variance is requested and its good faith efforts to...

  10. Impact of social media as an instructional component on content knowledge, attitudes, and public engagement related to global climate change

    Science.gov (United States)

    Greenberg, Sallie E.

    Social media (SM) are considered important avenues to reach citizens and engage them in social change. Given the widespread use of SM and their potential to enhance communication, they could also have significant influence when used as an educational tool. Educators are exploring whether classroom SM use has instructional benefits, such as enhancing interactivity and engagement. It is critical to understand the potential of SM for creating meaningful learning environments and public engagement pathways. Much work remains to understand the use of SM in this context and how to use them effectively. This study draws on active learning theory to examine the impact of SM as an instructional component with community college students learning to make connections among science, social responsibility, and global understanding in an environmental biology course (the Course). Using global climate change as a theme, the Course included a Facebook instructional component. A pretest--posttest, nonrandomized comparison group design was used to measure the impact of Facebook as an integrated component of the Course. The treatment and comparison groups were determined to be comparable based on demographics, access and ownership of digital devices, and SM use despite non-random assignment. No statistically significant differences were found between groups on these factors. The intervention consisted of semester-long required use of Facebook for the treatment group. The impact of the SM intervention was measured in three areas: (a) content knowledge, (b) attitudes toward climate change, and (c) public engagement actions and intentions to act. At the conclusion of the Course, no discernable difference was measured in content knowledge gains between the two groups. However, students who used Facebook experienced statistically significant differences in attitude, becoming increasingly concerned about global climate change. The comparison group demonstrated statistically significant

  11. Legal and Organizational Issues in Collaborative User-Created Content

    OpenAIRE

    Sarvas, Risto

    2005-01-01

    Introduction In this paper we look into issues that arise when people collaboratively create digital content and want to publicly distribute it. We identify and analyze the issues based on four case studies on amateur content production. In our analysis we discuss the issues both from the amateurs’ point of view, and also, from the game brand owners’ perspective. User-created content (UCC) in games has become popular as demonstrated by game-related skins, mods and extensions, screenshots, gam...

  12. 45 CFR 1180.48 - General conditions on publications.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false General conditions on publications. 1180.48... Conditions Which Must Be Met by a Grantee Publications and Copyrights § 1180.48 General conditions on publications. (a) Content of materials. Subject to any specific requirements that apply to its grant, a grantee...

  13. Web-Based Media Contents Editor for UCC Websites

    Science.gov (United States)

    Kim, Seoksoo

    The purpose of this research is to "design web-based media contents editor for establishing UCC(User Created Contents)-based websites." The web-based editor features user-oriented interfaces and increased convenience, significantly different from previous off-line editors. It allows users to edit media contents online and can be effectively used for online promotion activities of enterprises and organizations. In addition to development of the editor, the research aims to support the entry of enterprises and public agencies to the online market by combining the technology with various UCC items.

  14. 77 FR 67678 - Content Specifications and Shielding Evaluations for Type B Transportation Packages

    Science.gov (United States)

    2012-11-13

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0270] Content Specifications and Shielding Evaluations for... Commission) is issuing for public comment Draft Regulatory Issue Summary (RIS) 2012-XX, ``Content... Material,'' for the review of content specifications and shielding evaluations included in the Certificates...

  15. Language Learning of Gifted Individuals: A Content Analysis Study

    Science.gov (United States)

    Gokaydin, Beria; Baglama, Basak; Uzunboylu, Huseyin

    2017-01-01

    This study aims to carry out a content analysis of the studies on language learning of gifted individuals and determine the trends in this field. Articles on language learning of gifted individuals published in the Scopus database were examined based on certain criteria including type of publication, year of publication, language, research…

  16. AN INVESTIGATION OF TEACHERS’ PEDAGOGICAL SKILLS AND CONTENT KNOWLEDGE IN A CONTENT-BASED INSTRUCTION CONTEXT

    Directory of Open Access Journals (Sweden)

    Tengku Nor Rizan Tengku Mohamad Maasum

    2012-01-01

    Full Text Available Advocates of the content-based approach believed that a language can be learnt effectively when it is the medium of instruction rather than just a subject. Integrating English and content as part of instruction has become one of the cornerstones of second language pedagogy. Researchers claimed that there are many benefits of integrating English and content instruction. Among the benefits are the increase in students’ interest with content themes, meaningful input and understanding. In 2003, the Malaysian Ministry of Education introduced the teaching and learning of science and mathematics in English for Year One, Form One and Lower Six Form in all government public schools. This paper describes the challenges faced by teachers when they are required to teach content subjects such as science and mathematics in English. The focus of the paper is on the teachers’ pedagogical skills and content knowldge which comprises subject matter content, pedagogical approach, classroom management, use of resources, assessment, preparation of teaching materials, managing students, teachers’ compensatory communication strategies, use of first language and teachers’ perspectives of teaching content subjects in English. Data were obtained from a self-report questionnaire administered to 495 secondary school teachers in West Malaysia. Results from the study provide implications for school administrators in making decisions in assignment of capable teachers to teach the various levels of classes. Suggestions for teacher self-development and life-long learning efforts are also provided.

  17. AN INVESTIGATION OF TEACHERS’ PEDAGOGICAL SKILLS AND CONTENT KNOWLEDGE IN A CONTENT-BASED INSTRUCTION CONTEXT

    Directory of Open Access Journals (Sweden)

    Tengku Nor Rizan Tengku Mohamad Maasum

    2012-01-01

    Full Text Available Abstract: Advocates of the content-based approach believed that a language can be learnt effectively when it is the medium of instruction rather than just a subject.  Integrating English and content as part of instruction has become one of the cornerstones of second language pedagogy. Researchers claimed that there are many benefits of integrating English and content instruction.  Among the benefits are the increase in students’ interest with content themes, meaningful input and understanding. In 2003, the Malaysian Ministry of Education introduced the teaching and learning of science and mathematics in English for Year One, Form One and Lower Six Form in all government public schools. This paper describes the challenges faced by teachers when they are required to teach content subjects such as science and mathematics in English.  The focus of the paper is on the teachers’ pedagogical skills  and content knowldge which comprises subject matter content, pedagogical approach, classroom management, use of resources, assessment, preparation of teaching materials, managing students, teachers’ compensatory communication strategies, use of first language and teachers’ perspectives of teaching content subjects in English. Data were obtained from a self-report questionnaire administered to 495 secondary school teachers in West Malaysia. Results from the study provide implications for school administrators in making decisions in assignment of  capable teachers to teach the various levels of classes. Suggestions for teacher self-development and life-long learning efforts are also provided.   Key words: Content-based instruction, ESL instruction, second language, first language and second language pedagogy

  18. Publication Design.

    Science.gov (United States)

    Nelson, Roy Paul

    This book is designed to solve the problem of coordinating art and typography with content in publications. Through text and illustrations, this book suggests ways to make pages and spreads in magazines, newspapers, and books attractive and readable. As a book of techniques, it is directed at potential and practicing art directors, designers, and…

  19. Emerging nicotine delivery products. Implications for public health.

    Science.gov (United States)

    Benowitz, Neal L

    2014-02-01

    The idea of clean nicotine delivery systems that would satisfy nicotine craving and promote smoking cessation has been considered as a possible public health tool for many years. Nicotine medications have been useful for smoking cessation but have not found widespread popularity among smokers, perhaps because of slow nicotine delivery and other sensory characteristics that differ from cigarettes. Traditional smokeless tobacco delivers as much nicotine as cigarettes and has been advocated for harm reduction but contains carcinogenic nitrosamines and has not been proven to promote cessation. Furthermore, there is concern that dual use of smokeless tobacco and cigarettes may inhibit quitting smoking. Newer oral dissolvable tobacco products contain lower levels of toxicants than other smokeless tobacco but also deliver much less nicotine and have not been popular with consumers. Electronic cigarettes that aerosolize nicotine without generating toxic tobacco combustion products have become quite popular and hold promise as a way to attract smokers away from cigarettes, although efficacy in promoting smoking cessation has not yet been demonstrated. There are concerns about safety of long-term use, and there is evidence that youth, including nonsmokers, are taking up e-cigarette use. E-cigarettes are marketed for use when one cannot smoke conventional cigarettes, and such use might result in more persistent cigarette smoking. Although their benefits and risks are being vigorously debated, e-cigarettes or other clean nicotine delivery devices could play an important role as an adjunct to a U.S. Food and Drug Administration regulatory intervention to make cigarettes less addictive and in this context could contribute to the end of cigarette smoking and smoking-induced disease.

  20. Influencing Database Use in Public Libraries.

    Science.gov (United States)

    Tenopir, Carol

    1999-01-01

    Discusses results of a survey of factors influencing database use in public libraries. Highlights the importance of content; ease of use; and importance of instruction. Tabulates importance indications for number and location of workstations, library hours, availability of remote login, usefulness and quality of content, lack of other databases,…

  1. Mathematical Content of Curricula and Beginning Salaries of Graduating Students

    Science.gov (United States)

    Lee, B. Brian; Lee, Jungsun

    2009-01-01

    The authors examined an association between mathematical content in college-level curricula and beginning salaries of graduating students on the basis of data collected from a public university in the southern region of the United States. The authors classified the mathematical content requirements of the curricula into the following 5 groups…

  2. The formation of volatile N-nitrosamines in kikuYl grass silage

    African Journals Online (AJOL)

    sorbed into the blood of the ruminant and transferred to the milk (Juszkiewicz ... precision chopped and ensiled in a bunker silo at a dry mat- ter content of 3090 ... one purple spot (Rf 0,83) on the silica gel G plate, indicating the presence of a ...

  3. What are cancer centers advertising to the public?: a content analysis.

    Science.gov (United States)

    Vater, Laura B; Donohue, Julie M; Arnold, Robert; White, Douglas B; Chu, Edward; Schenker, Yael

    2014-06-17

    Although critics have expressed concerns about cancer center advertising, analyses of the content of these advertisements are lacking. To characterize the informational and emotional content of direct-to-consumer cancer center advertisements. Content analysis. Top U.S. consumer magazines (n = 269) and television networks (n = 44) in 2012. Types of clinical services promoted; information provided about clinical services, including risks, benefits, costs, and insurance availability; use of emotional advertising appeals; and use of patient testimonials were assessed. Two investigators independently coded advertisements using ATLAS.ti, and κ values ranged from 0.77 to 1.00. A total of 102 cancer centers placed 409 unique clinical advertisements in top media markets in 2012. Advertisements promoted treatments (88%) more often than screening (18%) or supportive services (13%). Benefits of advertised therapies were described more often than risks (27% vs. 2%) but were rarely quantified (2%). Few advertisements mentioned coverage or costs (5%), and none mentioned specific insurance plans. Emotional appeals were frequent (85%), evoking hope for survival (61%), describing cancer treatment as a fight or battle (41%), and inducing fear (30%). Nearly one half of advertisements included patient testimonials, which were usually focused on survival, rarely included disclaimers (15%), and never described the results that a typical patient may expect. Internet advertisements were not included. Clinical advertisements by cancer centers frequently promote cancer therapy with emotional appeals that evoke hope and fear while rarely providing information about risks, benefits, costs, or insurance availability. Further work is needed to understand how these advertisements influence patient understanding and expectations of benefit from cancer treatments. National Institutes of Health.

  4. An Exploratory Look at Graduate Public Relations Education.

    Science.gov (United States)

    Aldoory, Linda; Toth, Elizabeth L.

    2000-01-01

    Conducts a content analysis of web pages to examine 26 United States Masters degree programs in public relations for their degree requirements, core courses, public relations courses, and optional courses. Finds a lack of adherence to the recommendations of the Foundation for Public Relations Research and Education. (NH)

  5. Total Dietary Fiber Content of Selected Traditional Beverages in Egypt: A Brief Profile

    Directory of Open Access Journals (Sweden)

    Basil H. Aboul-Enein

    2015-11-01

    Full Text Available Escalating obesity rates have become a major public health concern in North Africa and the Middle East. Culturally-congruent dietary health education and strategies continue to be warranted to address this increasing public health crisis. Knowledge and familiarity with traditional foods and their nutritive value would assist public health practitioners in becoming culturally competent when educating on healthy eating patterns. The aim of this study is to provide a brief dietary profile of the total dietary fiber (TDF contents of selected traditional beverages in Egypt. Five cookbooks for Egyptian food recipes were reviewed for traditional beverages. Beverage recipes (n = 19 were selected and reviewed for their TDF content using the United States Department of Agriculture (USDA National Nutrient Database for Standard Reference (Release 27. The published values for TDF content were tabulated and reported per 100 mL of consumable portions. The highest TDF content was found in carob juice (8.0 g and the lowest found in peppermint tea (0.0 g with an overall TDF mean content of 2.8 g. Traditional beverages could be regarded as important sources of TDF within a healthy Egyptian dietary pattern. Cultural awareness and familiarities to traditional foods and their respective dietary profiles should be encouraged as an objective towards building culturally-competent health professionals and combating obesity in Egypt. Furthermore, developments of a traditional Egyptian food nutrient database for public access should be explored.

  6. Monitoring sodium content of restaurant foods: Public health challenges and opportunities

    Science.gov (United States)

    Excess sodium intake is a major preventable risk factor for high blood pressure, a leading cause for heart disease and stroke. The majority of sodium intake comes from packaged and restaurant foods. At present, data on the sodium content of restaurant foods is limited. The purpose of this study i...

  7. Tests to evaluate public health disease reporting systems in local public health agencies (electronic resource)

    National Research Council Canada - National Science Library

    Ricci, Karen; Lurie, Nicole; Stoto, Michael A; Wasserman, Jeffrey; Dausey, David J; Meade, Barbara; Diamond, Alexis; Molander, Roger C

    2005-01-01

    ... to evaluate the ability to receive and respond to case reports 24 hours a day, 7 days a week. We refined these tests by beta-testing them at 20 metropolitan area local public health agencies across the country over the course of 10 months. The contents of this manual will be of interest to public health professionals at the state and local l...

  8. Validity and Reliability of Malay Version of the Job Content Questionnaire among Public Hospital Female Nurses in Malaysia.

    Science.gov (United States)

    Amin, N A; Quek, K F; Oxley, J A; Noah, R M; Nordin, R

    2015-10-01

    The Job Content Questionnaire (M-JCQ) is an established self-reported instrument used across the world to measure the work dimensions based on the Karasek's demand-control-support model. To evaluate the psychometrics properties of the Malay version of M-JCQ among nurses in Malaysia. This cross-sectional study was carried out on nurses working in 4 public hospitals in Klang Valley area, Malaysia. M-JCQ was used to assess the perceived psychosocial stressors and physical demands of nurses at their workplaces. Construct validity of the questionnaire was examined using exploratory factor analysis (EFA). Cronbach's α values were used to estimate the reliability (internal consistency) of the M-JCQ. EFA showed that 34 selected items were loaded in 4 factors. Except for psychological job demand (Cronbach's α 0.51), the remaining 3 α values for 3 subscales (job control, social support, and physical demand) were greater than 0.70, indicating acceptable internal consistency. However, an item was excluded due to poor item-total correlation (rMalaysia.

  9. Trialed production of low protein irradiated natural rubber latex in factory scale by gamma irradiation technique

    International Nuclear Information System (INIS)

    Utama, Marga; Herwinarni, S.; Halik, H.M.; Siswanto; Suharyanto; Syamsu, Y.; Handoko, B.

    2006-01-01

    Four tons fresh field natural rubber latex (FNRL) with total solid content 30% were added with 2 phr (part hundred ratio of rubber) normal butyl acrylate (nBA) then irradiated by gamma rays at 25 kGy. The irradiated FNRL was centrifuged, then the properties of irradiated centrifuged natural rubber latex (INRL) and its film were measured before and after storage for 5 months. It is found that the INRL is stable latex during storage in 5 months, with lowest protein, and free nitrosamine content. The tensile strength of INRL film was 24-27 MPa, and modulus 600% was 1,5-2,0 MPa, elongation at break was 900%, and hardness was 27-29 Shore A, while the extractable protein content less than 100 μg/g. (author)

  10. A PUBLIC CATALOG OF STELLAR MASSES, STAR FORMATION AND METALLICITY HISTORIES, AND DUST CONTENT FROM THE SLOAN DIGITAL SKY SURVEY USING VESPA

    International Nuclear Information System (INIS)

    Tojeiro, Rita; Wilkins, Stephen; Heavens, Alan F.; Panter, Ben; Jimenez, Raul

    2009-01-01

    We applied the VESPA algorithm to the Sloan Digital Sky Survey final data release of the Main Galaxies and Luminous Red Galaxies samples. The result is a catalog of stellar masses, detailed star formation and metallicity histories and dust content of nearly 800,000 galaxies. We make the catalog public via a T-SQL database, which is described in detail in this paper. We present the results using a range of stellar population and dust models, and will continue to update the catalog as new and improved models are made public. We also present a brief exploration of the catalog, and show that the quantities derived are robust: luminous red galaxies can be described by one to three populations, whereas a main galaxy sample galaxy needs on average two to five; red galaxies are older and less dusty; the dust values we recover are well correlated with measured Balmer decrements and star formation rates are also in agreement with previous measurements. We find that whereas some derived quantities are robust to the choice of modelling, many are still not.

  11. Music Provision in UK Public Libraries

    Science.gov (United States)

    Dorney, Carl; McKnight, Cliff

    2004-01-01

    Public library music provision, as a less traditional role for public libraries, has always caused contention: a vital source of cultural materials within the community though never confirmed to be a core part of library services by the Government. This article concerns itself with a detailed consideration of the decline of music services over the…

  12. 12 CFR 563c.3 - Qualification of public accountant.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Qualification of public accountant. 563c.3... REQUIREMENTS Form and Content of Financial Statements § 563c.3 Qualification of public accountant. (See also 17 CFR 210.2-01.) The term “qualified public accountant” means a certified public accountant or licensed...

  13. Social computing for verifying social media content in breaking news

    OpenAIRE

    Middleton, Stuart; Papadopoulos, Symeon; Kompatsiaris, Yiannis

    2018-01-01

    Social media is the place to go for both journalists and the general public when news events break, offering a real-time source of eyewitness images and videos through platforms like YouTube, Instagram, and Periscope. Yet, the value of such content as a means of documenting and disseminating breaking news is compromised by the increasing amount of content misuse and false claims in social media. To this end, cost-effective social computing solutions for user-generated content verification are...

  14. Public sentiment and discourse about Zika virus on Instagram.

    Science.gov (United States)

    Seltzer, E K; Horst-Martz, E; Lu, M; Merchant, R M

    2017-09-01

    Social media have strongly influenced the awareness and perceptions of public health emergencies, and a considerable amount of social media content is now shared through images, rather than text alone. This content can impact preparedness and response due to the popularity and real-time nature of social media platforms. We sought to explore how the image-sharing platform Instagram is used for information dissemination and conversation during the current Zika outbreak. This was a retrospective review of publicly posted images about Zika on Instagram. Using the keyword '#zika' we identified 500 images posted on Instagram from May to August 2016. Images were coded by three reviewers and contextual information was collected for each image about sentiment, image type, content, audience, geography, reliability, and engagement. Of 500 images tagged with #zika, 342 (68%) contained content actually related to Zika. Of the 342 Zika-specific images, 299 were coded as 'health' and 193 were coded 'public interest'. Some images had multiple 'health' and 'public interest' codes. Health images tagged with #zika were primarily related to transmission (43%, 129/299) and prevention (48%, 145/299). Transmission-related posts were more often mosquito-human transmission (73%, 94/129) than human-human transmission (27%, 35/129). Mosquito bite prevention posts outnumbered safe sex prevention; (84%, 122/145) and (16%, 23/145) respectively. Images with a target audience were primarily aimed at women (95%, 36/38). Many posts (60%, 61/101) included misleading, incomplete, or unclear information about the virus. Additionally, many images expressed fear and negative sentiment, (79/156, 51%). Instagram can be used to characterize public sentiment and highlight areas of focus for public health, such as correcting misleading or incomplete information or expanding messages to reach diverse audiences. Copyright © 2017 The Royal Society for Public Health. Published by Elsevier Ltd. All rights

  15. From primary care to public health: using Problem-based Learning and the ecological model to teach public health to first year medical students.

    Science.gov (United States)

    Hoover, Cora R; Wong, Candice C; Azzam, Amin

    2012-06-01

    We investigated whether a public health-oriented Problem-Based Learning case presented to first-year medical students conveyed 12 "Population Health Competencies for Medical Students," as recommended by the Association of American Medical Colleges and the Regional Medicine-Public Health Education Centers. A public health-oriented Problem-Based Learning case guided by the ecological model paradigm was developed and implemented among two groups of 8 students at the University of California, Berkeley-UCSF Joint Medical Program, in the Fall of 2010. Using directed content analysis, student-generated written reports were coded for the presence of the 12 population health content areas. Students generated a total of 29 reports, of which 20 (69%) contained information relevant to at least one of the 12 population health competencies. Each of the 12 content areas was addressed by at least one report. As physicians-in-training prepare to confront the challenges of integrating prevention and population health with clinical practice, Problem-Based Learning is a promising tool to enhance medical students' engagement with public health.

  16. Enriching Discovery Layers: A Product Comparison of Content Enrichment Services Syndetic Solutions and Content Café 2

    Directory of Open Access Journals (Sweden)

    Allison DaSilva

    2014-10-01

    Full Text Available A comparative analysis of content enrichment services, Syndetic Solutions and Content Café 2, was undertaken to explore which service would provide public library users with a superior online search and discovery experience through the enriched data elements offered, specifically looking at the cover image data element and exploring what factors impact the display of said element. A data-set of 250 items in five different formats, including books, CDs, DVDs, e-books, and video games, was searched in four North American public libraries’ discovery layers to compare the integration, extent, and quality of the cover image data element supplied by Syndetic Solutions and Content Café 2. Based on an analysis of the URLs, ISBNs, and UPCs for each of the 250 items, it was determined that the integration, and therefore the display, of the cover image data element was impacted by: (1 whether or not an ISBN or UPC was listed in the MARC bibliographic record; (2 which ISBN or UPC was listed, as items could potentially have more than one; (3 the inclusion of both ISBNs and UPCs in the record and the settings of the discovery tool; (4 the order in which the ISBNs or UPCs were listed in the record; and (5 whether or not Syndetic Solutions or Content Café 2 had the image data in its database at the time of the search. The quality of the cover image displayed was found to be impacted by the size requested by the library and the size of the image provided by the publisher. These findings may also have implications for the integration of other enriched data elements.

  17. Washington Public Libraries Online: Collaborating in Cyberspace.

    Science.gov (United States)

    Wildin, Nancy

    1997-01-01

    Discussion of public libraries, the Internet, and the World Wide Web focuses on development of a Web site in Washington. Highlights include access to the Internet through online public access catalogs; partnerships between various types of libraries; hardware and software; HTML training; content design; graphics design; marketing; evaluation; and…

  18. Algorithms and Public Service Media

    OpenAIRE

    Sørensen, Jannick Kirk; Hutchinson, Jonathon

    2018-01-01

    When Public Service Media (PSM) organisations introduce algorithmic recommender systems to suggest media content to users, fundamental values of PSM are challenged. Beyond being confronted with ubiquitous computer ethics problems of causality and transparency, also the identity of PSM as curator and agenda-setter is challenged. The algorithms represents rules for which content to present to whom, and in this sense they may discriminate and bias the exposure of diversity. Furthermore, on a pra...

  19. Astronomical Content in Rongorongo Tablet Keiti

    DEFF Research Database (Denmark)

    Wieczorek, Rafal

    2011-01-01

    Th e fi eld of rongorongo research: the study of Easter Island’s native script is in a peculiar state at the moment. While relative progress has been made in structural and statistical analysis in the last decades, at the level of both single glyphs as well as entire texts, little to no advanceme...... has been achieved in the actual decipherment. To shed new light on rongorongo research, a hypothesis regarding the contents of tablet Keiti, one of the 25 obtained artifacts, is proposed. Th e content, as well as the meaning, of all but one of these 25 rongorongo texts is still unknown....... In this publication, an interpretation for the recto side of tablet Keiti is presented. It is argued that the tablet contains astronomical observations or instructions regarding the Rapa Nui lunar calendar, and is similar in content to the only other rongorongo text whose function has been partially ascertained......: tablet Mamari. If the calendrical contents of this artifact were confi rmed, this would be a major boost to our understanding of Oceania’s only native script....

  20. DEFINING THE CHEMICAL SPACE OF PUBLIC GENOMIC ...

    Science.gov (United States)

    The current project aims to chemically index the genomics content of public genomic databases to make these data accessible in relation to other publicly available, chemically-indexed toxicological information. By defining the chemical space of public genomic data, it is possible to identify classes of chemicals on which to develop methodologies for the integration of chemogenomic data into predictive toxicology. The chemical space of public genomic data will be presented as well as the methodologies and tools developed to identify this chemical space.

  1. ARES Education and Public Outreach

    Science.gov (United States)

    Allen, Jaclyn; Galindo, Charles; Graff, Paige; Willis, Kim

    2014-01-01

    The ARES Directorate education team is charged with translating the work of ARES scientists into content that can be used in formal and informal K-12 education settings and assisting with public outreach. This is accomplished through local efforts and national partnerships. Local efforts include partnerships with universities, school districts, museums, and the Lunar and Planetary Institute (LPI) to share the content and excitement of space science research. Sharing astromaterials and exploration science with the public is an essential part of the Directorate's work. As a small enclave of physical scientists at a NASA Center that otherwise emphasizes human space operations and engineering, the ARES staff is frequently called upon by the JSC Public Affairs and Education offices to provide presentations and interviews. Scientists and staff actively volunteer with the JSC Speaker's Bureau, Digital Learning Network, and National Engineers Week programs as well as at Space Center Houston activities and events. The education team also participates in many JSC educator and student workshops, including the Pre-Service Teacher Institute and the Texas Aerospace Scholars program, with workshop presentations, speakers, and printed materials.

  2. Amylose content decreases during tuber development in potato.

    Science.gov (United States)

    Jansky, Shelley; Fajardo, Diego

    2016-10-01

    Potato starch is composed primarily of amylopectin and amylose in an approximately 3:1 ratio. Amylose is considered to be nutritionally desirable in North American and European markets, so there is interest in finding strategies to increase the amylose content of potato starch. There is also interest in marketing 'baby' potatoes, which are harvested when they are physiologically immature. This study was carried out to determine weekly changes in amylose content in potato tubers of 11 North American cultivars during the growing season. The trial was repeated across 3 years. We determined that amylose content is highest early and it decreases in a linear fashion as the growing season progresses. Mean amylose content across cultivars and years declined from 30.0% in late June to 26.8% in late August. The rate of decrease varied across years, with slopes of linear regression plots ranging from -0.17 in 2012 to -0.74 in 2011. Amylose content in tuber starch varied among cultivars, with the highest levels observed in Ranger Russet (30.7%) and White Pearl (31.6%); it was lowest in Kennebec (25.7%) and Langlade (25.6%). This study adds to a growing body of literature on the nutritional value of immature potato tubers. In addition to having higher levels of some phytonutrients, as reported in other studies, immature tubers have a higher proportion of amylose in the starch. This is nutritionally desirable in affluent regions where high fiber content is more important than calories from carbohydrates. Published 2016. This article is a U.S. Government work and is in the public domain in the USA. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

  3. 22 CFR 64.4 - Contents of application.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Contents of application. 64.4 Section 64.4 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES PARTICIPATION BY FEDERAL EMPLOYEES IN... and address of contact in the United States with whom communication may be made with respect to the...

  4. A comparative content analysis of media reporting of sports betting in Australia: lessons for public health media advocacy approaches.

    Science.gov (United States)

    David, Jennifer L; Thomas, Samantha L; Randle, Melanie; Bowe, Steven J; Daube, Mike

    2017-11-14

    Harmful gambling is a significant public health issue. There has been widespread discussion in the Australian media about the extent and impact of sports betting on the Australian community, particularly relating to young men and children. Given the role that the media plays in influencing policy change and political agendas, and the acknowledgement that media based advocacy is a fundamental component of successful advocacy campaigns, this research aimed to investigate how different stakeholder groups discuss sports betting within the Australian print media. The study uses this information to provide recommendations to guide public health media advocacy approaches. A quantitative content analysis of print media articles was conducted during two significant Parliamentary Inquiries about sports betting - (1) The Joint Select Committee Inquiry into the Advertising and Promotion of Gambling Services in Sport (2012/2013), and (2) 'The Review of Illegal Offshore Wagering (2015/2016). A total of 241 articles from 12 daily Australian newspapers were analysed. Statistical analysis was used to compare frequency of, and changes in, themes, voices and perspectives over time. Discussions about the marketing and communication of sports betting was a main theme in media reporting (n = 165, 68.5%), while discussions about gambling reform decreased significantly across the two time periods (p sports betting industry (p sporting code (p sports betting is important in developing effective public health advocacy approaches. This study indicates that discussions about the marketing strategies utilised by the sports betting industry was still a main theme in media articles. However, discussions relating to sports betting reforms, in particular to protect individuals who may be vulnerable to the harm associated with these products and their promotional strategies (for example children and young men) decreased during the time periods. Public health advocates may seek to address the

  5. Contents and purpose of financing activities: problems of definition

    OpenAIRE

    М. І. Дамірчиєв

    2015-01-01

    The author explores the purpose and content of financial activities. Focuses attention on the relationship categories "public financial activities" and "financial activities of the State," examines the relationship of financial activity to the financial system.

  6. Vgi Based Urban Public Transport

    Science.gov (United States)

    Teymurian, F.; Alesheikh, A. A.; Alimohammadi, A.; Sadeghi-Niaraki, A.

    2013-09-01

    Recent advances in information technology have made geographic information system (GIS) a powerful and affordable tool for planning and decision making in various fields such as the public transportation. These technologies such as the social network (e.g. face-book, twitter), new technologies such as ubiquitous, mobile, Web 2.0, geo tagging and RFID can help to create better shapes and forms of the communication and geo-collaboration for public. By using these, user-generated content and spatial information can be easily and quickly produced and shared in a dynamic, interactive, multimedia and distributed environment. The concept of volunteered geographic information (VGI) has been introduced by the transaction from consultation to content interaction. VGI describes any type of content that has a geographic element and has been voluntarily collected. In other words, ordinary users; without a professional training, can participate in generating and using the spatial information. As a result, the gaps between the producers and users of GIS and spatial information, has been considerably reduced. Public transportation is one of the most important elements of the transportation system. Rapid growth of the cities has resulted in high increase of demand for the public transportation which created new challenges. Improvement of the desirability of public transportation can increase its efficiency, reduction of the environmental pollution (such as air and noise pollution), traffic problems, and fuel consumption. Hence, development of an urban public transportation system which is responsive to citizen's need and motivates them to use public transportation system is one of the most important objectives and issues that urban planners and designers are concerned about. One solution to achieve this, goal is to develop public transportation system by assistance from the system users. According to approach, users are considered as the valuable resources, because people who are

  7. Association between drinking water uranium content and cancer risk in Bavaria, Germany

    Energy Technology Data Exchange (ETDEWEB)

    Radespiel-Troeger, M.; Meyer, M. [Population-based cancer registry Bavaria, Erlangen (Germany). Registration office

    2013-10-15

    To evaluate the possible association between uranium (U) content in public drinking water on the one hand and the risk of cancer of the colorectum, lung, female breast, prostate, kidney, and urinary bladder, total cancer, and leukemia on the other hand in Bavaria, an ecologic study on the level of municipalities was performed. Cancer incidence data for the years 2002-2008 were obtained from the population-based cancer registry Bavaria according to sex. Current U content data of public drinking water on the level of municipalities were obtained from a publicly available source. The possible association between drinking water U content and cancer risk adjusted for average socio-economic status was evaluated using Poisson regression. Drinking water U content was below 20 μg/L in 458 out of 461 included municipalities. We found a significantly increased risk of leukemia in men in the intermediate (U level, 1.00-4.99 μg/L; relative risk [RR], 1.14) and in the highest U exposure category (U level, ≥ 5 μg/L; RR, 1.28). Moreover, in women, a significantly elevated risk was identified with respect to kidney cancer in the highest exposure category (RR, 1.16) and with respect to lung cancer in the intermediate exposure category (RR, 1.12). The slightly increased risk of leukemia in men, kidney cancer in women, and lung cancer in women may require further investigation. If an increased cancer risk is confirmed, preventive measures (e.g., introduction of U filters in public water systems) may be considered.

  8. Public Libraries, Digital Literacy and Participatory Culture

    Science.gov (United States)

    McShane, Ian

    2011-01-01

    In recent years public libraries have experimented with user-generated or community-contributed content through the interactive tools of Web 2.0. For some commentators this not just establishes a new relationship between libraries and their publics, but signals the end of information hegemony and an "expert paradigm". Such claims need to…

  9. History and Content of Public Health Specialization Training and Employment Policies in the World and Turkey

    Directory of Open Access Journals (Sweden)

    Bulent Kilic

    2014-12-01

    Full Text Available Public health was accepted as a specialty in the mid-19th century in United Kingdom and Germany and, the beginning of 20th century in USA and Russia. In Turkey, public health specialization training started at Refik Saydam Hifzissihha Institute in 1958, at Hacettepe University in 1965 and at Ataturk University in 1967. While sanitation, communicable diseases and immunization subjects had priority in public health specialization training programs in the 1800s, health care management and epidemiology were customary curriculum in the second half of the 1900s. International Health Organizations, health planning and health economics subjects were included in curriculum during European Public Health School Directors meeting in 1966. Later on, public health has become a multidisciplinary field and psychology, sociology, anthropology, health economics and surveillance techniques were added to training programs. There are 520 public health specialists and 286 public health specialization students in Turkey in 2013. Specialization training programmes are offered in 57 departments. Half of the public health specialists work for the Ministry of Health (51%, while 47% of public health specialists work for universities. While 17% of public health specialists in the Ministry of Health worked in managerial positions, this ratio is increased to 25% in 2010. The Ministry of Health does not require public health specialization when assigning health managers. Authors strongly recommend that only the public health specialists should be assigned in managerial positions in the Provincial Directorate of Public Health and Community Health Centers. In addition, number of public health specialists working in central organization of Turkish Public Health Institution should be increased. [TAF Prev Med Bull 2014; 13(6.000: 495-504

  10. US Department of Energy environmental management advisory board public meeting

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    Contents of this publication include: list of participants; March 14, 1994--opening of public meeting and subcommittee reports, and public comment session; March 15, 1994--presentation by Thomas P. Grumbly, assistant secretary for environmental management, presentations by senior environmental management officials, and committee business.

  11. The changing information environment for nanotechnology: online audiences and content

    International Nuclear Information System (INIS)

    Anderson, Ashley A.; Brossard, Dominique; Scheufele, Dietram A.

    2010-01-01

    The shift toward online communication in all realms, from print newspapers to broadcast television, has implications for how the general public consumes information about nanotechnology. The goal of this study is threefold: to investigate who is using online sources for information and news about science and nanotechnology, to examine what the general public is searching for online with regards to nanotechnology, and to analyze what they find in online content of nanotechnology. Using survey data, we find those who report the Internet as their primary source of science and technology news are diverse in age, more knowledgeable about science and nanotechnology, highly educated, male, and more diverse racially than users of other media. In a comparison of demographic data on actual visits by online users to general news and science Web sites, science sites attracted more male, non-white users from the Western region of the United States than news sites did. News sites, on the other hand, attracted those with a slightly higher level of education. Our analysis of published estimates of keyword searches on nanotechnology reveals people are turning to the Internet to search for keyword searches related to the future, health, and applications of nanotechnology. A content analysis of online content reveals health content dominates overall. Comparisons of content in different types of sites-blogs, government, and general sites-are conducted.

  12. The changing information environment for nanotechnology: online audiences and content

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Ashley A., E-mail: aaanderson3@wisc.edu; Brossard, Dominique; Scheufele, Dietram A. [University of Wisconsin-Madison, Department of Life Sciences Communication (United States)

    2010-05-15

    The shift toward online communication in all realms, from print newspapers to broadcast television, has implications for how the general public consumes information about nanotechnology. The goal of this study is threefold: to investigate who is using online sources for information and news about science and nanotechnology, to examine what the general public is searching for online with regards to nanotechnology, and to analyze what they find in online content of nanotechnology. Using survey data, we find those who report the Internet as their primary source of science and technology news are diverse in age, more knowledgeable about science and nanotechnology, highly educated, male, and more diverse racially than users of other media. In a comparison of demographic data on actual visits by online users to general news and science Web sites, science sites attracted more male, non-white users from the Western region of the United States than news sites did. News sites, on the other hand, attracted those with a slightly higher level of education. Our analysis of published estimates of keyword searches on nanotechnology reveals people are turning to the Internet to search for keyword searches related to the future, health, and applications of nanotechnology. A content analysis of online content reveals health content dominates overall. Comparisons of content in different types of sites-blogs, government, and general sites-are conducted.

  13. Effect of Smokeless Tobacco on Surface Roughness of Dental Restorations

    Science.gov (United States)

    2016-05-01

    peer pressure.  Ingredients  found in smokeless tobacco include:  polonium   210 , n­nitrosamines, formaldehyde,  nicotine, cadmium, cyanide, arsenic...flavors, preservatives, and sugars are also added.  Polynuclear aromatic  hydrocarbons,  polonium   210 , and n­nitrosamines represent the chemical...N­nitrosamines in tobacco by super critical fluid extraction. Journal of   Agricultural and  Food  Chemistry 43, 916–922.     24 Brunnemann KD, Hoffmann D, Qi J

  14. In vitro and in vivo studies of the carcinogenic, toxic and genotoxic activities of the air pollutants SO2 and NOx, separately and in combination with carcinogenic polycyclic aromatic hydrocarbons and N-nitrosamines. In vivo- und in vitro-Studien zur carcinogenen, toxischen und genschaedigenden Wirkung von Luftschadstoffen (SO sub 2 , NO sub x , PAH, N-Nitrosoverbindungen, allein und in Kombination)

    Energy Technology Data Exchange (ETDEWEB)

    Schmezer, P; Zeller, W J; Klein, R G; Pool-Zobel, B L [Deutsches Krebsforschungszentrum, Heidelberg (Germany, F.R.). Inst. fuer Toxikologie und Chemotherapie

    1990-04-01

    Previous studies with different in vitro cell systems had shown that the DNA-damaging activity of several carcinogens may be decreased by SO{sub 2} and NO{sub x}. Experiments to elucidate possible mechanisms responsible for the observed effects were conducted. Comparative studies with the DNA-repair inhibitor novobiocin revealed that the reduction of benzo(a)pyrene (BaP) induced DNA-single strand breaks (DNA-SSB) in fetal hamster lung cells (FHLC) is probably caused by an inhibition of DNA-repair processes. Experiments with the Salmonella typhimurium mutagenicity assay showed that neither SO{sub 2} nor NO{sub x} influence the overall rate of BaP metabolism. Although it has been shown that both gases are able to influence appropriate enzyme activities, the net yield of mutagenic BaP metabolites is not altered. Finally, new investigations with primary rat hepatocytes revealed that no decrease of N-nitrosamine genotoxicity (DNA-SBB) was observed following simultaneous gas and nitrosamine exposure. With this system experiments are underway to elucidate if, in contrast, local influences (lung, nasal mucosa) are triggered by the in vivo combination treatment (SO{sub 2} and N-nitrosodimethylamine, NDMA). The present status of an ongoing inhalation study for carcinogenic activity of NDMA with and without the simultaneous application of the air pollutants is reported. The histopathological analysiss of the treatment groups receiving only NDMA exposure showed that even with an exposure as low as 0.04 ppm NDMA in the breathing air, which leads to a daily intake of 10 {mu}g NDMA/kg during 207 days of application, a 36% rate of tumor induction was observed.

  15. Nuclear education in public health and nursing

    International Nuclear Information System (INIS)

    Winder, A.E.; Stanitis, M.A.

    1988-01-01

    Twenty-three public health schools and 492 university schools of nursing were surveyed to gather specific information on educational programs related to nuclear war. Twenty public health schools and 240 nursing schools responded. Nuclear war-related content was most likely to appear in disaster nursing and in environmental health courses. Three schools of public health report that they currently offer elective courses on nuclear war. Innovative curricula included political action projects for nuclear war prevention

  16. Report of the Public's Right to Information Task Force

    International Nuclear Information System (INIS)

    Rubin, D.M.

    1979-10-01

    Information is presented concerning the public information chronology; Met Ed public relations; flow of public information during the accident at Three Mile Island; flow of public information on five key events during the accident at Three Mile Island; the journalist's perspective; content analysis of mass media coverage of the accident; local radio news coverage of the accident; and qualitative survey of newspaper coverage of the accident

  17. Report of the Public's Right to Information Task Force

    International Nuclear Information System (INIS)

    Rubin, D.M.; Chaapel, H.A.; Cunningham, A.M.

    1979-10-01

    Information is presented concerning the public information chronology; MET ED public relations; flow of public information during the accident at Three Mile Island; flow of public information on five key events during the accident at Three Mile Island; the journalist's perspective; content analysis of mass media coverage of the accident; local radio news coverage of the accident; and qualitative survey of newspaper coverage of the accident

  18. Teaching Art to Teens in Public Libraries

    Science.gov (United States)

    Crawford Barniskis, Shannon

    2013-01-01

    One of the hottest terms among public librarians today is "content creation," which involves stuff that library patrons make instead of simply use in a library context. Videos, music, fiction, paintings, 3D printed materials, websites--all these are made in public libraries, and will increase in popularity as more libraries shift from purveyors of…

  19. Examining the scope and patterns of deliberate self-injurious cutting content in popular social media.

    Science.gov (United States)

    Miguel, Elizabeth M; Chou, Tommy; Golik, Alejandra; Cornacchio, Danielle; Sanchez, Amanda L; DeSerisy, Mariah; Comer, Jonathan S

    2017-09-01

    Social networking services (SNS) have rapidly become a central platform for adolescents' social interactions and media consumption patterns. The present study examined a representative sample of publicly accessible content related to deliberate self-injurious cutting across three SNS platforms: Twitter, Tumblr, and Instagram. Data collection simulated searches for publicly available deliberate self-injury content on Twitter, Tumblr, and Instagram. Over a six-month period at randomly generated time points, data were obtained by searching "#cutting" on each SNS platform and collecting the first 10 posts generated. Independent evaluators coded posts for presence of the following: (a) graphic content, (b) negative self-evaluations, (c) references to mental health terms, (d) discouragement of deliberate self-injury, and (e) recovery-oriented resources. Differences across platforms were examined. Data collection yielded a sample of 1,155 public posts (770 of which were related to mental health). Roughly 60% of sampled posts depicted graphic content, almost half included negative self-evaluations, only 9.5% discouraged self-injury, and Instagram posts displayed the greatest proportion of graphic content and negative self-evaluations, whereas Twitter exhibited the smallest proportion of each. Findings characterize the graphic nature of online SNS deliberate self-injury content and the relative absence of SNS-posted resources for populations seeking out deliberate self-injurious cutting content. Mental health professionals must recognize the rapidly changing landscape of adolescent media consumption, influences, and social interaction as they may pertain to self-harm patterns. © 2017 Wiley Periodicals, Inc.

  20. 43 CFR 46.415 - Environmental impact statement content, alternatives, circulation and filing requirements.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Environmental impact statement content... Impact Statements § 46.415 Environmental impact statement content, alternatives, circulation and filing requirements. The Responsible Official may use any environmental impact statement format and design as long as...

  1. TechTrends 2010-2015: A Content Analysis

    Science.gov (United States)

    Stauffer, Eric

    2017-01-01

    This study is a content analysis of articles published within the journal "TechTrends" from 2000 to 2015. The study reveals that the publication "TechTrends" has increased the overall number of peer reviewed original papers over the last 6 years. The author describes the proportion of these original papers per volume and…

  2. Algorithms and Public Service Media

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk; Hutchinson, Jonathon

    2018-01-01

    When Public Service Media (PSM) organisations introduce algorithmic recommender systems to suggest media content to users, fundamental values of PSM are challenged. Beyond being confronted with ubiquitous computer ethics problems of causality and transparency, also the identity of PSM as curator...

  3. Data Content Protection for Virtual Libraries Heritage

    Directory of Open Access Journals (Sweden)

    Mihai DOINEA

    2016-01-01

    Full Text Available This paper presents aspects of digital content protection in virtual library systems. The legislation aspects are presented to better emphasize the need of new security mechanisms. Integrated library systems architecture is presented with focus on their main purpose, manipulating and rendering digital content to end-users. The cultural heritage stored in such systems is an important asset that needs to be protected against malicious manipulation. The characteristics of a smart virtual library, supported by an integrated library system, are analyzed and a security model is proposed for implementation, based on its particularities. The model aims to be an interface between the interactions of anonymous users with the Online Public Access Catalog of a virtual library that assures the protection of digital content. Conclusions are drawn to better support the idea of cultural persistence by the use of Information Systems.

  4. Video content analysis of surgical procedures.

    Science.gov (United States)

    Loukas, Constantinos

    2018-02-01

    In addition to its therapeutic benefits, minimally invasive surgery offers the potential for video recording of the operation. The videos may be archived and used later for reasons such as cognitive training, skills assessment, and workflow analysis. Methods from the major field of video content analysis and representation are increasingly applied in the surgical domain. In this paper, we review recent developments and analyze future directions in the field of content-based video analysis of surgical operations. The review was obtained from PubMed and Google Scholar search on combinations of the following keywords: 'surgery', 'video', 'phase', 'task', 'skills', 'event', 'shot', 'analysis', 'retrieval', 'detection', 'classification', and 'recognition'. The collected articles were categorized and reviewed based on the technical goal sought, type of surgery performed, and structure of the operation. A total of 81 articles were included. The publication activity is constantly increasing; more than 50% of these articles were published in the last 3 years. Significant research has been performed for video task detection and retrieval in eye surgery. In endoscopic surgery, the research activity is more diverse: gesture/task classification, skills assessment, tool type recognition, shot/event detection and retrieval. Recent works employ deep neural networks for phase and tool recognition as well as shot detection. Content-based video analysis of surgical operations is a rapidly expanding field. Several future prospects for research exist including, inter alia, shot boundary detection, keyframe extraction, video summarization, pattern discovery, and video annotation. The development of publicly available benchmark datasets to evaluate and compare task-specific algorithms is essential.

  5. The European Public on Social Media

    DEFF Research Database (Denmark)

    Tarta, Ancuta-Gabriela

    This study explorers the European public on social media by discussing the case of communicative interactions taking place on the official Facebook page of the European Parliament. Based on the theoretical framework conceptualizing the public and the public sphere on social network sites, the study...... examines the European social media public from two perspectives. The first is a top-down, institutional perspective of European Parliament, based on a case-study approach to the way this European institution constructs and addresses the public through its social media communication. The second is a bottom......-up perspective of the public of social media users, informed by a content analysis of Facebook comments and a discourse analysis of live chat interactions with Members of the European Parliament. Results confirm a discursive potential of the Facebook public of users. In the case of the Facebook comment threads...

  6. Elaboration and Evaluation of Contents about Hearing Health Inserted in Cybertutor.

    Science.gov (United States)

    Corrêa, Camila de Castro; Silva, Ricelly Avila da; Blasca, Wanderléia Quinhoneiro

    2014-04-01

    Introduction Cybertutor (electronic tutor) is a type of information and communication technology to disseminate knowledge about hearing, aiming at the prevention of hearing alterations and, when needed, early treatment, in addition to social inclusion of the hearing impaired. However, it is important to evaluate the level of language used in the content and the subjective perception of the target public regarding improvements of the tool. Objective To improve content about hearing health inserted in a cybertutor and to evaluate the level of legibility and the quality of the content and material made available. Method For the construction of the content, text and audiovisual resources were used, based on scientific publications, and were evaluated objectively with Flesch Reading Ease test and subjectively with a questionnaire created by the authors and answered by 10 ninth-year pupils. Results Two modules on hearing health were created, "Hearing Health" and "Intervention and Rehabilitation," which received Flesch scores of 50.8 and 51.4%, respectively, making it necessary to have a sixth- to ninth-year education to understand the material. The students' evaluation in reference to language and material showed that 55.5% considered the contents excellent; 38.2% classified the contents as satisfactory; 6.3% considered them reasonable; and 0% classified them as unsatisfactory. Conclusion The contents inserted in the cybertutor about hearing health presented a language level considered easy for the age group of the target population, in addition to receiving good subjective evaluation from the pupils, facilitating access to the information.

  7. Elaboration and Evaluation of Contents about Hearing Health Inserted in Cybertutor

    Science.gov (United States)

    Corrêa, Camila de Castro; Silva, Ricelly Avila da; Blasca, Wanderléia Quinhoneiro

    2014-01-01

    Introduction Cybertutor (electronic tutor) is a type of information and communication technology to disseminate knowledge about hearing, aiming at the prevention of hearing alterations and, when needed, early treatment, in addition to social inclusion of the hearing impaired. However, it is important to evaluate the level of language used in the content and the subjective perception of the target public regarding improvements of the tool. Objective To improve content about hearing health inserted in a cybertutor and to evaluate the level of legibility and the quality of the content and material made available. Method For the construction of the content, text and audiovisual resources were used, based on scientific publications, and were evaluated objectively with Flesch Reading Ease test and subjectively with a questionnaire created by the authors and answered by 10 ninth-year pupils. Results Two modules on hearing health were created, “Hearing Health” and “Intervention and Rehabilitation,” which received Flesch scores of 50.8 and 51.4%, respectively, making it necessary to have a sixth- to ninth-year education to understand the material. The students' evaluation in reference to language and material showed that 55.5% considered the contents excellent; 38.2% classified the contents as satisfactory; 6.3% considered them reasonable; and 0% classified them as unsatisfactory. Conclusion The contents inserted in the cybertutor about hearing health presented a language level considered easy for the age group of the target population, in addition to receiving good subjective evaluation from the pupils, facilitating access to the information. PMID:25992075

  8. Controllership as a Governance Instrument in the Public Sector

    Directory of Open Access Journals (Sweden)

    Mônica Clark Nunes Cavalcante

    2013-03-01

    Full Text Available Controllership is considered a Corporate Governance instrument, to the extent that it can contribute to reduce information asymmetry ad conflicts of interest, deriving from agency problems between organizational owners and managers, by making available information that permit valuing the organization and the extent to which its goals are achieved. Disclosure and accountability are basic pillars of Corporate Governance as well as Controllership. The Public Sector Committee (PSC of the International Federation of Accountants (IFAC developed a study on governance for the public context, considering that governance principles should be present in public entities, reflected in four dimensions, two of which related to control and to the availability of external reports (Federação Internacional dos Contadores [IFAC] (2001. The main goal in this research is to identify which information the Office of the Comptroller General (CGU makes available on its website comply with the type and contents of IFAC recommendations for control and external reports, as governance dimensions in the public sector. Through a bibliographic and documentary research, it was verified that only information related to budgetary and financial reports comply with the type and contents recommended by IFAC. The research also revealed that information related to internal audit and annual Government accountability partially address the contents recommended by IFAC.

  9. How people react to Zika virus outbreaks on Twitter? A computational content analysis.

    Science.gov (United States)

    Fu, King-Wa; Liang, Hai; Saroha, Nitin; Tse, Zion Tsz Ho; Ip, Patrick; Fung, Isaac Chun-Hai

    2016-12-01

    Zika-related Twitter incidence peaked after the World Health Organization declared an emergency. Five themes were identified from Zika-related Twitter content: (1) societal impact of the outbreak; (2) government, public and private sector, and general public responses to the outbreak; (3) pregnancy and microcephaly: negative health consequences related to pregnant women and babies; (4) transmission routes; and (5) case reports. User-generated contents sites were preferred direct information channels rather than those of the government authorities. Copyright © 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  10. Introduction: Alternative Public School Financing.

    Science.gov (United States)

    Disend, David S., Ed.

    2000-01-01

    Argues that time and money are the two critical resources to allocate in any plan, and certainly regarding public education. Discusses four important elements in the debate about the use of resources: efficiency, content, effectiveness, and fairness. Outlines difficulties and questions regarding school funding. (SR)

  11. Arrangement and processing of monographic publications in youth sections of public libraries

    Directory of Open Access Journals (Sweden)

    Mateja Ločniškar-Fidler

    2006-01-01

    Full Text Available A systematic and transparent layout of library material on book shelves of public libraries is one of the essential conditions for successful viewing and searching of materials. The research tried to determine the contemporary classification system of library material for the youth. The data needed for the research was gathered and analyzed by a questionnaire completed by five randomly selected central public libraries. Special collections, arrangement and classification of certain fiction and specialized monographic publications for infants, teenagers and adolescents were analyzed. It was of our interest to observe whether the libraries assign the elements of a call number - which are evident on the library material and in online catalogs – according to standards and current instructions. The article also focuses on the unity and differences of the technical processing, and on color and/or image of labels which additionally explain the classification and the contents of the monographic publications for the youth.

  12. PUBLIC RELATIONS AS AN INFORMATION PROCESS PHENOMENON

    Directory of Open Access Journals (Sweden)

    TKACH L. M.

    2016-06-01

    Full Text Available Formulation of the problem. If public relations as a phenomenon of information management are examined, we deal with the question of knowledge content and nature of relationship of PR with environment, ability to manage the perception and attitude of people to events in the environment; ensure priority of information over other resources. Goal. To investigate the concept of "public relations" of foreign and domestic experts; consider the typology of the public and the "laws" of public opinion; define the basic principles according to which relations with public should be built, and to identify PR activities as a kind of social communication. Conclusions. Public relations on the basis of advanced information and communication technologies create fundamentally new opportunities for information control and influence on public consciousness.

  13. Transparency for Sponsored Content : Analysing Codes of Ethics in Public Relations, Marketing, Advertising and Journalism

    OpenAIRE

    Ikonen, Pasi; Luoma-aho, Vilma; Bowen, Shannon A.

    2017-01-01

    As sponsored content is gaining ground globally, the boundaries between strategic communication, advertising and journalism are blurring. As sponsored content becomes more common, it raises novel ethical concerns that no industry alone can answer, such as How much disclosure is needed for transparency? Self-regulation via codes of ethics has been suggested as a remedy to meet the rising transparency expectations, and this article analysed 40 codes of ethics in the fields of communication, adv...

  14. Denmark’s Master of Public Governance Program

    DEFF Research Database (Denmark)

    Greve, Carsten; Pedersen, Anne Reff

    2017-01-01

    This paper focuses on Denmark’s Master of Public Governance and its assessments and lessons learned. Denmark is seen to have an efficient economy and public sector, a digitalized public service delivery system, and an advanced work–life balance. The Danish government invested substantial resources...... into developing a Master of Public Governance program – a flexible and modular program for public managers to take over a period of up to six years. The paper focuses on the Copenhagen version of the Master of Public Governance program. More than 1000 public managers from central, regional and local government...... are now active in pursuing an executive public management education through this program. The development, structure, content and the innovative teaching ideas are presented. The available data, including an official evaluation of the MPG program, is used to assess the program and present some lessons...

  15. Exploiting Publication Contents and Collaboration Networks for Collaborator Recommendation.

    Directory of Open Access Journals (Sweden)

    Xiangjie Kong

    Full Text Available Thanks to the proliferation of online social networks, it has become conventional for researchers to communicate and collaborate with each other. Meanwhile, one critical challenge arises, that is, how to find the most relevant and potential collaborators for each researcher? In this work, we propose a novel collaborator recommendation model called CCRec, which combines the information on researchers' publications and collaboration network to generate better recommendation. In order to effectively identify the most potential collaborators for researchers, we adopt a topic clustering model to identify the academic domains, as well as a random walk model to compute researchers' feature vectors. Using DBLP datasets, we conduct benchmarking experiments to examine the performance of CCRec. The experimental results show that CCRec outperforms other state-of-the-art methods in terms of precision, recall and F1 score.

  16. A comparative content analysis of media reporting of sports betting in Australia: lessons for public health media advocacy approaches

    Directory of Open Access Journals (Sweden)

    Jennifer L. David

    2017-11-01

    Full Text Available Abstract Background Harmful gambling is a significant public health issue. There has been widespread discussion in the Australian media about the extent and impact of sports betting on the Australian community, particularly relating to young men and children. Given the role that the media plays in influencing policy change and political agendas, and the acknowledgement that media based advocacy is a fundamental component of successful advocacy campaigns, this research aimed to investigate how different stakeholder groups discuss sports betting within the Australian print media. The study uses this information to provide recommendations to guide public health media advocacy approaches. Methods A quantitative content analysis of print media articles was conducted during two significant Parliamentary Inquiries about sports betting - (1 The Joint Select Committee Inquiry into the Advertising and Promotion of Gambling Services in Sport (2012/2013, and (2 'The Review of Illegal Offshore Wagering (2015/2016. A total of 241 articles from 12 daily Australian newspapers were analysed. Statistical analysis was used to compare frequency of, and changes in, themes, voices and perspectives over time. Results Discussions about the marketing and communication of sports betting was a main theme in media reporting (n = 165, 68.5%, while discussions about gambling reform decreased significantly across the two time periods (p < 0.0001. The presence of sports betting industry (p < 0.0001, sporting code (p < 0.0001 and public health expert (p = 0.001 voices all increased significantly across the two time periods. There were very few (n = 11, 4.6% voices from those who had experienced gambling harm. Finally, while there were significantly fewer articles taking the perspective that regulation changes were needed to protect vulnerable sub-populations (p < 0.0001, articles that had a neutral perspective about the need for regulation change increased

  17. Cured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: a population based case-control study.

    Science.gov (United States)

    Liu, Chen-Yu; Hsu, Yi-Hsiang; Wu, Ming-Tsang; Pan, Pi-Chen; Ho, Chi-Kung; Su, Li; Xu, Xin; Li, Yi; Christiani, David C

    2009-01-13

    Consumption of cured/smoked meat and fish leads to the formation of carcinogenic N-nitroso compounds in the acidic stomach. This study investigated whether consumed cured/smoked meat and fish, the major dietary resource for exposure to nitrites and nitrosamines, is associated with childhood acute leukemia. A population-based case-control study of Han Chinese between 2 and 20 years old was conducted in southern Taiwan. 145 acute leukemia cases and 370 age- and sex-matched controls were recruited between 1997 and 2005. Dietary data were obtained from a questionnaire. Multiple logistic regression models were used in data analyses. Consumption of cured/smoked meat and fish more than once a week was associated with an increased risk of acute leukemia (OR = 1.74; 95% CI: 1.15-2.64). Conversely, higher intake of vegetables (OR = 0.55; 95% CI: 0.37-0.83) and bean-curd (OR = 0.55; 95% CI: 0.34-0.89) was associated with a reduced risk. No statistically significant association was observed between leukemia risk and the consumption of pickled vegetables, fruits, and tea. Dietary exposure to cured/smoked meat and fish may be associated with leukemia risk through their contents of nitrites and nitrosamines among children and adolescents, and intake of vegetables and soy-bean curd may be protective.

  18. Standards-based Content Resources: A Prerequisite for Content Integration and Content Interoperability

    Directory of Open Access Journals (Sweden)

    Christian Galinski

    2010-05-01

    Full Text Available Objective: to show how standards-based approaches for content standardization, content management, content related services and tools as well as the respective certification systems not only guarantee reliable content integration and content interoperability, but also are of particular benefit to people with special needs in eAccessibility/eInclusion. Method: document MoU/MG/05 N0221 ''Semantic Interoperability and the need for a coherent policy for a framework of distributed, possibly federated repositories for all kinds of content items on a world-wide scale''2, which was adopted in 2005, was a first step towards the formulation of global interoperability requirements for structured content. These requirements -based on advanced terminological principles- were taken up in EU-projects such as IN-SAFETY (INfrastructure and SAFETY and OASIS (Open architecture for Accessible Services Integration and Standardization. Results: Content integration and content interoperability are key concepts in connection with the emergence of state-of-the-art distributed and federated databases/repositories of structured content. Given the fact that linguistic content items are increasingly combined with or embedded in non-linguistic content items (and vice versa, a systemic and generic approach to data modelling and content management has become the order of the day. Fulfilling the requirements of capability for multilinguality and multimodality, based on open standards makes software and database design fit for eAccessibility/eInclusion from the outset. It also makes structured content capable for global content integration and content interoperability, because it enhances its potential for being re-used and re-purposed in totally different eApplications. Such content as well as the methods, tools and services applied can be subject to new kinds of certification schemes which also should be based on standards. Conclusions: Content must be totally reliable in some

  19. Disease Detection or Public Opinion Reflection? Content Analysis of Tweets, Other Social Media, and Online Newspapers During the Measles Outbreak in the Netherlands in 2013

    Science.gov (United States)

    Harmsen, Irene Anhai; Broekhuizen, Emma; Clijnk, Rutger; De Melker, Hester; Paulussen, Theo; Kok, Gerjo; Ruiter, Robert; Das, Enny

    2015-01-01

    institutes to respond immediately and appropriately to those public concerns. More research is required to develop an automatic coding system that captures content and user’s characteristics that are most relevant to the diseases within the National Immunization Program and related public health events and can inform official responses. PMID:26013683

  20. Disease detection or public opinion reflection? Content analysis of tweets, other social media, and online newspapers during the measles outbreak in The Netherlands in 2013.

    Science.gov (United States)

    Mollema, Liesbeth; Harmsen, Irene Anhai; Broekhuizen, Emma; Clijnk, Rutger; De Melker, Hester; Paulussen, Theo; Kok, Gerjo; Ruiter, Robert; Das, Enny

    2015-05-26

    to those public concerns. More research is required to develop an automatic coding system that captures content and user's characteristics that are most relevant to the diseases within the National Immunization Program and related public health events and can inform official responses.

  1. Interaction Design for Public Spaces

    DEFF Research Database (Denmark)

    Kortbek, Karen Johanne

    2008-01-01

    In this abstract I describe the doctorial research project "Interaction Design for Public Spaces". The objective of the project is to explore and design interaction contexts in culture related public spaces such as museums, experience centres and festivals. As a perspective on this domain, I...... will focus on the usage of the body as an interaction device. Furthermore, the project will involve a dramaturgic take on communication and design of interactive systems in the pursuit of new ways to stage the interactive contexts. The outcome of the project will be guidelines and conceptual frameworks which...... will help interaction designers when designing for bodily movement, and communicating and staging interactive content in public spaces....

  2. Anticarcinogenic effect of betel leaf extract against tobacco carcinogens.

    Science.gov (United States)

    Padma, P R; Lalitha, V S; Amonkar, A J; Bhide, S V

    1989-06-01

    Epidemiological studies have implicated that betel quid offers some protection to tobacco induced carcinogenesis. Earlier studies in our laboratory have shown betel leaf extract (BLE) to be antimutagenic against standard mutagens and tobacco-specific N'-nitrosamines (TSNA), N'-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). In the present study, we have tested the anticarcinogenic effect of BLE using Swiss male mice. Two protocols of study were used to test this effect. In the first protocol, the effect of BLE was tested against the standard carcinogen benzo[a]pyrene (BP) using Wattenberg's stomach tumor model, Cancer Res., 41 (1981) 2820-2823. In this protocol, BLE inhibited the tumorigenicity of BP to a significant extent. In the second protocol, the effect of BLE against the two tobacco-specific nitrosamines, NNN and NNK was studied using long-term studies on Swiss male mice. The nitrosamines were administered on the tongues of the mice, while the BLE was supplied in drinking water. Two doses of NNN (22 mg and 72 mg) and one dose of NNK (22 mg) were used. In this study, it was observed that the number of tumor bearing animals decreased, but the difference was significant only in the group treated with the low dose of NNN in combination with BLE. However, in all the BLE treated animals, irrespective of the dose of nitrosamine, the hepatic vitamin A and C levels were elevated significantly as compared to the corresponding nitrosamine-treated controls. These results indicate that BLE has a promising anticarcinogenic role to play in tobacco induced cancer.(ABSTRACT TRUNCATED AT 250 WORDS)

  3. Formation of Tobacco Specific Nitrosamines in Mainstream Cigarette Smoke; Part 1, FTC Smoking

    Directory of Open Access Journals (Sweden)

    Moldoveanu SC

    2014-12-01

    Full Text Available This report evaluates the formation of nitrosonornicotine (NNN and of 4-(methyl-nitrosamino-1-(3-pyridyl-1-butanone (NNK from nicotine, and of NNN from nornicotine in the mainstream smoke of a burning cigarette. The cigarettes analyzed in the study were Kentucky reference cigarettes 1R4F and 2R4F, and five other cigarettes, three of them having tobaccos with low levels of tobacco specific nitrosamines (TSNAs. All cigarettes had ‘tar’ levels around 10 mg [where ‘tar’ is defined as the weight of total wet particulate matter (TPM minus the weight of nicotine and water]. Cigarettes were smoked according to the U.S. Federal Trade Commission (FTC puffing regimen, using a 35 mL puff volume, 2 sec puff duration and 60 sec puff intervals. Three separate experiments were performed in this study to evaluate the proportion of TSNAs transferred from preexistent tobacco TSNAs and the proportion formed during smoking (pyrosynthesized. In one experiment, the results were obtained by GC/MS analysis of 13C3-TSNAs formed in smoke when 13C3-nicotine was intentionally added to cigarettes. Another experiment used GC analysis with chemiluminescence detection of TSNAs from smoke before and after an excess of nornicotine was intentionally added to cigarettes, and another experiment consisted of LC/MS/MS analysis of 2H4-TSNAs formed in the smoke when 2H4-nicotine and when 2H4-nornicotine were intentionally added to cigarettes. The use of different analytical methods for the study of TSNA formation conveyed an additional level of confidence regarding the reliability of the results obtained. It was found that NNK was generated during smoking from nicotine with 3 × 10-5% to 8 × 10-5% conversion (0.3 ppm to 0.8 ppm conversion of the nicotine while the result for NNN generation was not conclusive. One experiment demonstrated the formation of NNN from nicotine between 4 × 10-5% and 1.5 × 10-4% (0.4 ppm to 1.5 ppm reported to nicotine, but another experiment did not

  4. What Are Cancer Centers Advertising to the Public? A Content Analysis

    Science.gov (United States)

    Vater, Laura B.; Donohue, Julie M.; Arnold, Robert; White, Douglas B; Chu, Edward; Schenker, Yael

    2015-01-01

    Background Although critics have expressed concerns about cancer center advertising, the content of these advertisements has not been analyzed. Objective To characterize the informational and emotional content of cancer center advertisements. Design Systematic analysis of all cancer center advertisements in top U.S. consumer magazines (N=269) and television networks (N=44) in 2012. Measurements Using a standardized codebook, we assessed (1) types of clinical services promoted; (2) information provided about clinical services, including risks, benefits, and costs; (3) use of emotional advertising appeals; and (4) use of patient testimonials. Two investigators independently coded advertisements using ATLAS.ti. Kappa values ranged from 0.77 to 1.0. Results A total of 102 cancer centers placed 409 unique clinical advertisements in top media markets in 2012. Advertisements promoted treatments (88%) more often than screening (18%) or supportive services (13%; padvertised therapies were described more often than risks (27% vs. 2%; padvertisements mentioned insurance coverage or costs (5%). Emotional appeals were frequent (85%), most often evoking hope for survival (61%), describing cancer treatment as a fight or battle (41%), and evoking fear (30%). Nearly half of advertisements included patient testimonials, usually focused on survival or cure. Testimonials rarely included disclaimers (15%) and never described the results a typical patient might expect. Limitations Internet advertisements were not included. Conclusions Clinical advertisements by cancer centers frequently promote cancer therapy using emotional appeals that evoke hope and fear while rarely providing information about risks, benefits, or costs. Further work is needed to understand how these advertisements influence patient understanding and expectations of benefit from cancer treatments. PMID:24863081

  5. Public Perceptions Regarding Use of Virtual Reality in Health Care: A Social Media Content Analysis Using Facebook.

    Science.gov (United States)

    Keller, Michelle Sophie; Park, Hannah J; Cunningham, Maria Elena; Fouladian, Joshua Eleazar; Chen, Michelle; Spiegel, Brennan Mason Ross

    2017-12-19

    Virtual reality (VR) technology provides an immersive environment that enables users to have modified experiences of reality. VR is increasingly used to manage patients with pain, disability, obesity, neurologic dysfunction, anxiety, and depression. However, public opinion regarding the use of VR in health care has not been explored. Understanding public opinion of VR is critical to ensuring effective implementation of this emerging technology. This study aimed to examine public opinion about health care VR using social listening, a method that allows for the exploration of unfiltered views of topics discussed on social media and online forums. In March 2016, NBC News produced a video depicting the use of VR for patient care. The video was repackaged by NowThis, a social media news website, and distributed on Facebook by Upworthy, a news aggregator, yielding 4.3 million views and 2401 comments. We used Microsoft Excel Power Query and ATLAS.ti software (version 7.5, Scientific Software Development) to analyze the comments using content analysis and categorized the comments around first-, second-, and third-order concepts. We determined self-identified gender from the user's Facebook page and performed sentiment analysis of the language to analyze whether the perception of VR differed by gender using a Pearson's chi-square test. Out of the 1614 analyzable comments, 1021 (63.26%) were attributed to female Facebook users, 572 (35.44%) to male users, and 21 (1.30%) to users of unknown gender. There were 1197 comments coded as expressing a positive perception about VR (74.16%), 251 coded as expressing a negative perception and/or concern (15.56%), and 560 coded as neutral (34.70%). Informants identified 20 use cases for VR in health care, including the use of VR for pain and stress reduction; bed-bound individuals; women during labor; and patients undergoing chemotherapy, dialysis, radiation, or imaging procedures. Negative comments expressed concerns about radiation

  6. Content and Grade Trends in State Assessments and NAEP.

    Directory of Open Access Journals (Sweden)

    William D. Schafer

    2007-08-01

    Full Text Available Each state is required by the No Child Left Behind Act to report the percents of its students who have reached a score level called - proficient- or above for certain grades in the content areas of reading (or a similar construct and math. Using 2005 data from public web sites of states and the National Assessment of Educational Progress (NAEP, state-to-state differences in percents were analyzed, both unconditionally and conditionally on NAEP, for (1 trend across content areas (horizontal moderation, (2 trend across grade levels (vertical moderation, and (3 consistency with NAEP. While there was considerable variation from state to state, especially on an idealistic-realistic dimension, the results generally show that states are relatively consistent in trends across grades and contents.

  7. 36 CFR 1206.84 - What is the format and content of the narrative report?

    Science.gov (United States)

    2010-07-01

    ... content of the narrative report? 1206.84 Section 1206.84 Parks, Forests, and Public Property NATIONAL... Grant Administration § 1206.84 What is the format and content of the narrative report? (a) Interim narrative reports should state briefly the performance objectives and activities for the entire grant and...

  8. Human perception considerations for 3D content creation

    Science.gov (United States)

    Green, G. Almont

    2011-03-01

    Observation and interviews with people viewing autostereoscopic 3D imagery provides evidence that there are many human perception considerations required for 3D content creation. A study was undertaken whereby it was witnessed that certain test autostereoscopic imagery elicited a highly emotional response and engagement, while other test autostereoscopic imagery was given only a passing glance. That an image can be viewed with a certain level of stereopsis does not make it compelling. By taking into consideration the manner in which humans perceive depth and the space between objects, 3D content can achieve a level of familiarity and realness that is not possible with single perspective imagery. When human perception issues are ignored, 3D imagery can be undesirable to viewers and a negative bias against 3D imagery can occur. The preparation of 3D content is more important than the display technology. Where human perception, as it is used to interpret reality, is not mimicked in the creation of 3D content, the general public typically express a negative bias against that imagery (where choices are provided). For some, the viewing of 3D content that could not exist naturally, induces physical discomfort.

  9. Improving Elementary School Students’ English Vocabulary Through Local Cultural Content Materials

    OpenAIRE

    Frans Manurung; Ignatius Harjanto

    2015-01-01

    Abstract Elementary students of a certain public school in Indonesia had difficulties in learning English. One of the crucial problems was learning English vocabulary. In an attempt to help the students learn and improve English vocabulary, the researchers decided to use CAR to teach English vocabulary with local cultural content materials. The aim of this study was to investigate how the teaching of English vocabulary with local cultural content materials contributed to the improvement ...

  10. Evaluation of microbial content of some soybean milk products ...

    African Journals Online (AJOL)

    Evaluating the microbiological content of soybean milk, highly consumed by the public is the aim of this research work. Ten samples of soybean milk, locally prepared by different manufacturers were used for the study. The microbial load and identity of the microorganisms present were determined using standard ...

  11. A Room with a View: Observations on "Unanticipated" Licensing Agreements and Born Digital Content

    Science.gov (United States)

    Lapinski, P. Scott

    2012-01-01

    One of the many challenges that content creators and repository administrators are both struggling with in this "born digital" information environment is the "ownership" of content. After several years of engaging directly with researchers across their campus and providing seminars on the National Institutes of Health (NIH) Public Access Policy,…

  12. 36 CFR 1206.82 - What is the format and content of the financial report?

    Science.gov (United States)

    2010-07-01

    ... content of the financial report? 1206.82 Section 1206.82 Parks, Forests, and Public Property NATIONAL... Grant Administration § 1206.82 What is the format and content of the financial report? Grant recipients must submit financial reports on Standard Form 269, if there is program income to report, or Standard...

  13. Content Dynamics Over the Network Cloud

    Science.gov (United States)

    2015-11-04

    AFRL-AFOSR-CL-TR-2015-0003 Content dynamics over the network cloud Fernando Paganini UNIVERSIDAD ORT URUGUAY CUAREIM 1451 MONTEVIDEO, 11100 UY 11/04...approved for public release. FINAL PERFORMANCE REPORT: 7-15-2012 to 7-14-2015 AFOSR GRANT NUMBER: FA9550-12-1-0398 PI: Fernando Paganini Universidad ORT...349-362, Apr 2014. 7. M. Zubeldía, “From resource allocation to neighbor selection in peer-to-peer networks”, MS Thesis, Universidad ORT Uruguay

  14. Caffeine Content Labeling: A Missed Opportunity for Promoting Personal and Public Health

    OpenAIRE

    Kole, Jon; Barnhill, Anne

    2013-01-01

    Current regulation of caffeine-containing products is incoherent, fails to protect consumers' interests, and should be modified in multiple ways. We make the case for one of the regulatory reforms that are needed: all consumable products containing added caffeine should be required by the Food and Drug Administration (FDA) to include caffeine quantity on their labels. Currently, no foods or beverages that contain caffeine are required to include caffeine content on their labels. Strengthening...

  15. The Funding of Public Service Media

    DEFF Research Database (Denmark)

    Lowe, Gregory F.; Berg, Christian E.

    2013-01-01

    This article provides an overview of the financial situation for public service broadcasting in European Union member countries, situating concerns about the sector's economic value-for-money in a broader discourse about contention over socio-political values. The authors argue that debate about...

  16. Institutional Branding: A Content Analysis of Public Service Announcements from American Universities

    Science.gov (United States)

    Clayton, Michael J.; Cavanagh, Kevin V.; Hettche, Matt

    2012-01-01

    American universities receive millions of dollars worth of media exposure every year via Public Service Announcements (PSAs) broadcast during their respective school's athletic competitions. This research explores the message strategies and executional devices used by NCAA FBS (National Collegiate Athletic Association Football Bowl Subdivision)…

  17. [Dynamics and interactions between the university community and public health 2.0].

    Science.gov (United States)

    Rodríguez-Gómez, Rodolfo

    2016-01-01

    To explore the experiences of a group of participants in a university community with the web in general and with digital contents on public health, to describe their motivations and to understand how social networks influence their interaction with content on public health. Qualitative research. Deep semi-structured interviews were conducted to understand the phenomenon. Five categories emerged after the study: socialization and internalization of the cyberculture, social marketing linked to the web and public health, culture of fear and distrust, the concept of health, and the health system and public health. Participants have internalized the web and have given it a strong symbolic capital. The challenges of public health 2.0 are not only to achieve interaction with users and to get a place in cyberspace, but also to fight against the stigma of the "public" and to take advantage of the influence of the web on small-world networks to communicate.

  18. 10 CFR 455.62 - Contents of a technical assistance program.

    Science.gov (United States)

    2010-01-01

    ... 455.62 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND... Schools, Hospitals, Units of Local Government, and Public Care Institutions § 455.62 Contents of a... and installation of each energy conservation measure, discussing pertinent assumptions as necessary...

  19. Online Communication And PR in Romanian Public Administration. The Case Study of Public Institutions From Transylvania

    Directory of Open Access Journals (Sweden)

    Delia Cristina BALABAN

    2016-02-01

    Full Text Available New technologies such as Internet and new media introduce new challenges for public communication. Private companies from Romania use in a very creative way the new tools of Web 2.0, such as social media. In the Romanian public sector, especially in the public administration there are important steps taken towards a modern communication. Based on the example of over 40 city halls, city councils, prefectures and county councils from Transylvania, the present paper analyzes the use of new media tools in public communication by applying content analysis and in-depth interviews with the PR representatives in those institutions in two stages, 2011 and 2015. The most important advantages of online communication in public administration are high speed, cost reduction, reaching young audiences, etc. Nevertheless, there are also critical voices that express possible risks such as exclusion of audience groups that have no online media literacy.

  20. Research on the crisis of public relation in library

    International Nuclear Information System (INIS)

    Liu Shanyong

    2010-01-01

    In modem society, a variety of organizations including libraries will inevitably encounter all kinds of crises. Organizations can pull through and create good impression if they deal with correctly the crisis of public relation. The article defines the crisis, the crisis of public relation, and analyzes the characteristics and types of the crises in library. Finally the article emphasizes the contents and six strategies of the crisis of public relation in library. (authors)

  1. Privacy with Public Access: Digital Memorials on QR Codes

    DEFF Research Database (Denmark)

    Gotved, Stine

    2015-01-01

    takes the departure in gravestones with QR-codes; objects at once physical and digital, underhandedly putting presumably private content within public reach. A plethora of issues of privacy and publicness are at play within the study's two connected but rather different empirical spaces: the physical...... in the borderland between private and public is exemplified, and with the presentation, we are ensuring a continued discussion on privacy as well as legacy in our digital society....

  2. Public and Private Sector Managers: Are They Really That Different?

    Science.gov (United States)

    1982-04-01

    16, 17, 18, or equivalent public law positions) and private sector managers and executives in terms of job content, job characteristics, and...2) both groups of managers indicate that they do not have time for reflective, systematic planning, and (3) public and private sector managers agree

  3. Evaluation of natural radionuclide contents in the building industry

    International Nuclear Information System (INIS)

    Mrnustik, J.

    1990-01-01

    A model was adopted to calculate the effective annual dose equivalent for inhabitants of rooms built from three combinations of building materials with different natural radionuclide contents. The mean natural radionuclide contents of Czech building materials were assessed based on extensive data. The vast majority of materials satisfy the requirement that the annual dose equivalent lie within the 1-2 mSv range. Materials with average radionuclide contents contribute to the radiation burden of the population approximately twofold with respect to the natural background, which is acceptable. Raw materials used for the production of building materials must be checked for radioactivity, this checking, however, should be sensible; hasty purchases of expensive measuring instrumentation, establishment of specialized institutions, etc., as a response to public phobia is unreasonable. (P.A.). 2 tabs

  4. Review of a Proposed Quarterly Coal Publication

    Energy Technology Data Exchange (ETDEWEB)

    1981-01-01

    This Review of a Proposed Quartery Coal Publication contains findings and recommendations regarding the content of a new summary Energy Information Administration (EIA) coal and coke publication entitled The Quarterly Coal Review (QCR). It is divided into five sections: results of interviews with selected EIA data users; identification of major functions of the coal and coke industries; analysis of coal and coke data collection activities; evaluation of issues conerning data presentation including recommendations for the content of the proposed QCR; and comparison of the proposed QCR with other EIA publications. Major findings and recommendations are as follows: (1) User interviews indicate a definite need for a compehensive publication that would support analyses and examine economic, supply and demand trends in the coal industry; (2) the organization of the publication should reflect the natural order of activities of the coal and coke industries. Based on an analysis of the industries, these functions are: production, stocks, imports, exports, distribution, and consumption; (3) current EIA coal and coke surveys collect sufficient data to provide a summary of the coal and coke industries on a quarterly basis; (4) coal and coke data should be presented separately. Coke data could be presented as an appendix; (5) three geographic aggregations are recommended in the QCR. These are: US total, coal producing districts, and state; (6) coal consumption data should be consolidated into four major consumer categories: electric utilities, coke plants, other industrial, and residential commercial; (7) several EIA publications could be eliminated by the proposed QCR.

  5. An Analysis of Geography Content in Relation to Geography for Life Standards in Oman

    Science.gov (United States)

    Al-Nofli, Mohammed Abdullah

    2018-01-01

    Since the publication of "Geography for Life: National Geography Standards" in the United States (Geography Education Standards Project, 1994), it has been widely used to develop quality curriculum materials for what students should know and able to do in geography. This study compared geography content taught in Omani public schools…

  6. Estimating Snow Cover from Publicly Available Images

    OpenAIRE

    Fedorov, Roman; Camerada, Alessandro; Fraternali, Piero; Tagliasacchi, Marco

    2016-01-01

    In this paper we study the problem of estimating snow cover in mountainous regions, that is, the spatial extent of the earth surface covered by snow. We argue that publicly available visual content, in the form of user generated photographs and image feeds from outdoor webcams, can both be leveraged as additional measurement sources, complementing existing ground, satellite and airborne sensor data. To this end, we describe two content acquisition and processing pipelines that are tailored to...

  7. The use of content analysis in the assessment of medical controversies.

    Science.gov (United States)

    de Villiers, F P

    1991-12-01

    Medicine is fraught with controversies, and several strategies have been developed in order to reach rational conclusions. Examples are using more subjects or an improved research design, developing consensus statements or using meta-analysis. An additional strategy is described in this paper. The language content of scientific papers is examined to establish whether the authors use factual (informational) language or emotional appeals (directive language) to convince the reader. This type of content analysis is then applied to a sample controversy. The paper shows that directive language content analysis can be applied effectively to scientific publications to clarify the basis of and reasoning behind some controversies.

  8. Contributions of Public Health to nursing practice

    Directory of Open Access Journals (Sweden)

    Káren Mendes Jorge de Souza

    Full Text Available ABSTRACT Objective: Analyze the perceptions of undergraduate nursing students about the contributions of public health to nursing practice in the Unified Health System. Method: Qualitative Descriptive Study. Data collection was carried out through semi-directed interviews with 15 students. The language material was analyzed according to content and thematic analysis. Results: Thematic categories were established, namely: "Perceptions about Public Health" and "Contribution of Public Health to nursing practice in the Unified Health System". Final considerations: Perceptions about Public Health are diversified, but converge to the recognition of this field as the basis for training nurses qualified to work in the SUS with technical competence, autonomy and focusing on the integrality in health care.

  9. Regulating alcohol advertising: content analysis of the adequacy of federal and self-regulation of magazine advertisements, 2008-2010.

    Science.gov (United States)

    Smith, Katherine C; Cukier, Samantha; Jernigan, David H

    2014-10-01

    We analyzed beer, spirits, and alcopop magazine advertisements to determine adherence to federal and voluntary advertising standards. We assessed the efficacy of these standards in curtailing potentially damaging content and protecting public health. We obtained data from a content analysis of a census of 1795 unique advertising creatives for beer, spirits, and alcopops placed in nationally available magazines between 2008 and 2010. We coded creatives for manifest content and adherence to federal regulations and industry codes. Advertisements largely adhered to existing regulations and codes. We assessed only 23 ads as noncompliant with federal regulations and 38 with industry codes. Content consistent with the codes was, however, often culturally positive in terms of aspirational depictions. In addition, creatives included degrading and sexualized images, promoted risky behavior, and made health claims associated with low-calorie content. Existing codes and regulations are largely followed regarding content but do not adequately protect against content that promotes unhealthy and irresponsible consumption and degrades potentially vulnerable populations in its depictions. Our findings suggest further limitations and enhanced federal oversight may be necessary to protect public health.

  10. Open Innovation as Business Model Game-changer in the Public Sector

    DEFF Research Database (Denmark)

    Gaur, Aakanksha; Osella, Michele; Ferro, Enrico

    2017-01-01

    Organizations are increasingly looking to tap into external knowledge sources through open innovation initiatives. Most public sector agencies are in the early stages of adoption of open innovation and are in the process of defining relevant issues. Once such issue concerns how open innovation...... be better aligned with open innovation strategies (in our case crowdsourcing). Our results indicate that in adopting a crowd-based open innovation strategy, the content, structure and governance dimensions of public sector business model need to be aligned accordingly. The content of the business model...

  11. Using Twitter to Understand Public Perceptions Regarding the #HPV Vaccine: Opportunities for Public Health Nurses to Engage in Social Marketing.

    Science.gov (United States)

    Keim-Malpass, Jessica; Mitchell, Emma M; Sun, Emily; Kennedy, Christine

    2017-07-01

    Given the degree of public mistrust and provider hesitation regarding the human papillomavirus (HPV) vaccine, it is important to explore how information regarding the vaccine is shared online via social media outlets. The purpose of this study was to evaluate the content of messaging regarding the HPV vaccine on the social media and microblogging site Twitter, and describe the sentiment of those messages. This study utilized a cross-sectional descriptive approach. Over a 2-week period, Twitter content was searched hourly using key terms "#HPV and #Gardasil," which yielded 1,794 Twitter posts for analysis. Each post was then analyzed individually using an a priori coding strategy and directed content analysis. The majority of Twitter posts were written by lay consumers and were sharing commentary about a media source. However, when actual URLs were shared, the most common form of share was linking back to a blog post written by lay users. The vast majority of content was presented as polarizing (either as a positive or negative tweet), with 51% of the Tweets representing a positive viewpoint. Using Twitter to understand public sentiment offers a novel perspective to explore the context of health communication surrounding certain controversial issues. © 2017 Wiley Periodicals, Inc.

  12. U.S. Public Relations from an International Perspective: Curricular Issues and Objectives.

    Science.gov (United States)

    Pratt, Cornelius B.; Ogbondah, Chris W.

    This paper establishes a rationale for international public relations courses in the curricula of university public relations education in the U.S. and outlines the content of such courses. Disagreements between practitioners and educators on a blueprint for public relations education are documented. Developments pointing to a crucial need for…

  13. Library Web Sites in Pakistan: An Analysis of Content

    Science.gov (United States)

    Qutab, Saima; Mahmood, Khalid

    2009-01-01

    Purpose: The purpose of this paper is to investigate library web sites in Pakistan, to analyse their content and navigational strengths and weaknesses and to give recommendations for developing better web sites and quality assessment studies. Design/methodology/approach: Survey of web sites of 52 academic, special, public and national libraries in…

  14. The Public Health Practitioner of the Future.

    Science.gov (United States)

    Erwin, Paul Campbell; Brownson, Ross C

    2017-08-01

    The requisite capacities and capabilities of the public health practitioner of the future are being driven by multiple forces of change, including public health agency accreditation, climate change, health in all policies, social media and informatics, demographic transitions, globalized travel, and the repercussions of the Affordable Care Act. We describe five critical capacities and capabilities that public health practitioners can build on to successfully prepare for and respond to these forces of change: systems thinking and systems methods, communication capacities, an entrepreneurial orientation, transformational ethics, and policy analysis and response. Equipping the public health practitioner with the requisite capabilities and capacities will require new content and methods for those in public health academia, as well as a recommitment to lifelong learning on the part of the practitioner, within an increasingly uncertain and polarized political environment.

  15. Constructing Public Space: Global Perspectives on Social Media and Popular Contestation

    NARCIS (Netherlands)

    Poell, T.; van Dijck, J.

    2016-01-01

    This introduction to the special section on the construction of public space in social media activism discusses (1) the types of social media practices involved in the construction of publicness during contemporary episodes of popular contention, (2) the particular political institutional contexts

  16. Adapting online learning for Canada's Northern public health workforce

    Directory of Open Access Journals (Sweden)

    Marnie Bell

    2013-08-01

    Full Text Available Background . Canada's North is a diverse, sparsely populated land, where inequalities and public health issues are evident, particularly for Aboriginal people. The Northern public health workforce is a unique mix of professional and paraprofessional workers. Few have formal public health education. From 2009 to 2012, the Public Health Agency of Canada (PHAC collaborated with a Northern Advisory Group to develop and implement a strategy to strengthen public health capacity in Canada's 3 northern territories. Access to relevant, effective continuing education was identified as a key issue. Challenges include diverse educational and cultural backgrounds of public health workers, geographical isolation and variable technological infrastructure across the north. Methods . PHAC's Skills Online program offers Internet-based continuing education modules for public health professionals. In partnership with the Northern Advisory Group, PHAC conducted 3 pilots between 2008 and 2012 to assess the appropriateness of the Skills Online program for Northern/Aboriginal public health workers. Module content and delivery modalities were adapted for the pilots. Adaptations included adding Inuit and Northern public health examples and using video and teleconference discussions to augment the online self-study component. Results . Findings from the pilots were informative and similar to those from previous Skills Online pilots with learners in developing countries. Online learning is effective in bridging the geographical barriers in remote locations. Incorporating content on Northern and Aboriginal health issues facilitates engagement in learning. Employer support facilitates the recruitment and retention of learners in an online program. Facilitator assets included experience as a public health professional from the north, and flexibility to use modified approaches to support and measure knowledge acquisition and application, especially for First Nations, Inuit and

  17. Adapting online learning for Canada's Northern public health workforce.

    Science.gov (United States)

    Bell, Marnie; MacDougall, Karen

    2013-01-01

    Canada's North is a diverse, sparsely populated land, where inequalities and public health issues are evident, particularly for Aboriginal people. The Northern public health workforce is a unique mix of professional and paraprofessional workers. Few have formal public health education. From 2009 to 2012, the Public Health Agency of Canada (PHAC) collaborated with a Northern Advisory Group to develop and implement a strategy to strengthen public health capacity in Canada's 3 northern territories. Access to relevant, effective continuing education was identified as a key issue. Challenges include diverse educational and cultural backgrounds of public health workers, geographical isolation and variable technological infrastructure across the north. PHAC's Skills Online program offers Internet-based continuing education modules for public health professionals. In partnership with the Northern Advisory Group, PHAC conducted 3 pilots between 2008 and 2012 to assess the appropriateness of the Skills Online program for Northern/Aboriginal public health workers. Module content and delivery modalities were adapted for the pilots. Adaptations included adding Inuit and Northern public health examples and using video and teleconference discussions to augment the online self-study component. Findings from the pilots were informative and similar to those from previous Skills Online pilots with learners in developing countries. Online learning is effective in bridging the geographical barriers in remote locations. Incorporating content on Northern and Aboriginal health issues facilitates engagement in learning. Employer support facilitates the recruitment and retention of learners in an online program. Facilitator assets included experience as a public health professional from the north, and flexibility to use modified approaches to support and measure knowledge acquisition and application, especially for First Nations, Inuit and Metis learners. Results demonstrate that

  18. 42 CFR 90.4 - Contents of requests for health assessments.

    Science.gov (United States)

    2010-10-01

    ... ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES ADMINISTRATIVE... assessment. (c) Each request for a health assessment should include, where possible: (1) Any other... 42 Public Health 1 2010-10-01 2010-10-01 false Contents of requests for health assessments. 90.4...

  19. Factors associated with the content of sex education in U.S. public secondary schools.

    Science.gov (United States)

    Landry, David J; Darroch, Jacqueline E; Singh, Susheela; Higgins, Jenny

    2003-01-01

    While sex education is almost universal in U.S. schools, its content varies considerably. Topics such as abstinence, and basic information on HIV and other sexually transmitted diseases (STDs), are commonly taught; birth control and how to access STD and contraceptive services are taught less often. Factors potentially associated with these variations need to be examined. Data on 1,657 respondents to a 1999 national survey of teachers providing sex education in grades 7-12 were assessed for variation in topics covered. Logistic regression was used to ascertain factors associated with instruction on selected topics. The content of sex education varied by region and by instructors' approach to teaching about abstinence and contraception. For example, teaching abstinence as the only means of pregnancy and STD prevention was more common in the South than in the Northeast (30% vs. 17%). Emphasizing the ineffectiveness of contraceptives was less common in the Northeast (17%) than in other regions (27-32%). Instructors teaching that methods are ineffective and presenting abstinence as teenagers' only option had significantly reduced odds of teaching various skills and topics (odds ratios, 0.1-0.5). Instructors' approach to teaching about methods is a very powerful indicator of the content of sex education. Given the well-documented relationship between what teenagers learn about safer sexual behavior and their use of methods when they initiate sexual activity, sex education in all U.S. high schools should include accurate information about condoms and other contraceptives.

  20. Public Engagement in Planetary Science through Europlanet Social Media

    Science.gov (United States)

    Heenatigala, T.

    2017-09-01

    From 'Save the Hubble' campaign to ESA's Rosetta mission, social media has played a major role in public engagement and continues to grow. However, with this growing number of social media platforms and the amount of content that goes public daily, the 'noise' level is high - making it difficult to reach a good, relevant audience. Hence, it's important to use different strategies with the content created, from launching a video to live session to issue a press release. Under the Horizon 2020, the Europlanet Media Centre[1] identifies the importance of using social media for outreach. Europlanet uses primary and secondary social media platforms strategically to engage with the followers and a new audience.

  1. Secretly political: Civic engagement in online publics in Kazakhstan

    DEFF Research Database (Denmark)

    Shklovski, Irina; Valtysson, Bjarki

    2012-01-01

    The proliferation of networked forms of communication has captured the attention of media and scholars alike. We have never had quite as many resources for communication as we have today, and such communicative potential has implications for social change. In this article we consider public spheres...... that emerge through communication in the digital realm, paying atten- tion to how networked publics operate within such spheres. We present results from a study of a popular local online discussion forum in Kazakhstan. Steeped in Habermas’s idea of the public sphere, this study focuses on cultural public...... spheres defined through engagement and participation of diverse publics. We consider a range of publics that might emerge, such as mundane-publics, issue-publics, and counter-publics and how these differ in their content and purpose. While the majority of work on networked publics has been situated...

  2. MVC for content management on the cloud

    OpenAIRE

    McGruder, Crystal A.

    2011-01-01

    Approved for public release; distribution is unlimited. Cloud computing portrays a new model for providing IT services over the Internet. In cloud computing, resources are accessed from the Internet through web-based tools. Although cloud computing offers reduced cost, increased storage, high automation, flexibility, mobility, and the ability of IT to shift focus, there are other concerns such as the management, organization and structure of content on the cloud that large organizations sh...

  3. Radiation preservation with reduced nitrites of bacon and other cured meats - a review

    International Nuclear Information System (INIS)

    Singh, H.

    1987-01-01

    The main problem caused by nitrite as a preservative is the formation of carcinogenic nitrosamines in bacon and other cured meats. This has led to a search for alternatives to the use of nitrite. Irradiation with reduced level of nitrite is a promising alternative to the use of current levels of nitrite. Radurization (radiation pasteurization) of bacon containing 20 to to 40 mg/kg of nitrite in evacuated packages, irradiated and stored at 4 degrees C, gives a product with good organoleptic qualities and extended shelf life of > 80 days vs. < days 30 days for the conventionally treated bacon. Radappertization (radiation sterilization) of bacon containing 20 mg/kg of nitrite at a dose of about 30 kGy, irradiated at -20 degrees or lower in evacuated packages, results in a product that is shelf stable for months to years at room temperature (∼ 25 degrees C). It has organoleptic properties comparable to commercial bacon in terms of color, flavor, odor and texture. Irradiation also reduces the nitrite and preformed nitrosamines present in bacon. Lower levels of nitrosamines are formed on cooking irradiated bacon containing presently used commercial levels of nitrite (120-150 mg/kg) and the levels of nitrosamines become negligible with 20 mg/kg of nitrite. Various aspects of preservation of bacon and other cured meats are reviewed in this report with emphasis on radiation processing. 357 refs

  4. Celebrity over science? An analysis of Lyme disease video content on YouTube.

    Science.gov (United States)

    Yiannakoulias, N; Tooby, R; Sturrock, S L

    2017-10-01

    Lyme disease has been a subject of medical controversy for several decades. In this study we looked at the availability and type of content represented in a (n = 700) selection of YouTube videos on the subject of Lyme disease. We classified video content into a small number of content areas, and studied the relationship between these content areas and 1) video views and 2) video likeability. We found very little content uploaded by government or academic institutions; the vast majority of content was uploaded by independent users. The most viewed videos tend to contain celebrity content and personal stories; videos with prevention information tend to be of less interest, and videos with science and medical information tend to be less liked. Our results suggest that important public health information on YouTube is very likely to be ignored unless it is made more appealing to modern consumers of online video content. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Tourist maps – definition, types and contents

    Directory of Open Access Journals (Sweden)

    Jancewicz Kacper

    2017-03-01

    Full Text Available Tourist maps are one of the most common groups of cartographic documents. Their variety in terms of content, subject matter and publication titles is a result of growing popularity of diverse forms of tourism activity. The aim of the authors of this article is to demonstrate issues related to tourist maps, including their variety in relation to contemporary forms of tourism. As tourist maps are constantly developing, the authors decided to propose a classification of tourist maps which is adequate from the point of view of the types of maps we currently distinguish. Taking into consideration the aim and type of tourism, the maps were divided into the following sub-groups: maps for sightseeing tourism, qualified tourism, and other tourism, as well as tourist city maps, and maps prepared for promotion and advertising of tourism. The first there categories were further divided into more detailed sub-categories and each of them was described briefly in terms of its content. The classification of maps based on their scales and form of content presentation was also included.

  6. Health Information Needs and Health Seeking Behavior During the 2014-2016 Ebola Outbreak: A Twitter Content Analysis.

    Science.gov (United States)

    Odlum, Michelle; Yoon, Sunmoo

    2018-03-23

    For effective public communication during major disease outbreaks like the 2014-2016 Ebola epidemic, health information needs of the population must be adequately assessed. Through content analysis of social media data, like tweets, public health information needs can be effectively assessed and in turn provide appropriate health information to address such needs. The aim of the current study was to assess health information needs about Ebola, at distinct epidemic time points, through longitudinal tracking. Natural language processing was applied to explore public response to Ebola over time from July 2014 to March 2015. A total 155,647 tweets (unique 68,736, retweet 86,911) mentioning Ebola were analyzed and visualized with infographics. Public fear, frustration, and health information seeking regarding Ebola-related global priorities were observed across time. Our longitudinal content analysis revealed that due to ongoing health information deficiencies, resulting in fear and frustration, social media was at times an impediment and not a vehicle to support health information needs. Content analysis of tweets effectively assessed Ebola information needs. Our study also demonstrates the use of Twitter as a method for capturing real-time data to assess ongoing information needs, fear, and frustration over time.

  7. Fighting obesity or obese persons? Public perceptions of obesity-related health messages.

    Science.gov (United States)

    Puhl, R; Peterson, J L; Luedicke, J

    2013-06-01

    This study examined public perceptions of obesity-related public health media campaigns with specific emphasis on the extent to which campaign messages are perceived to be motivating or stigmatizing. In summer 2011, data were collected online from a nationally representative sample of 1014 adults. Participants viewed a random selection of 10 (from a total of 30) messages from major obesity public health campaigns from the United States, the United Kingdom and Australia, and rated each campaign message according to positive and negative descriptors, including whether it was stigmatizing or motivating. Participants also reported their familiarity with each message and their intentions to comply with the message content. Participants responded most favorably to messages involving themes of increased fruit and vegetable consumption, and general messages involving multiple health behaviors. Messages that have been publicly criticized for their stigmatizing content received the most negative ratings and the lowest intentions to comply with message content. Furthermore, messages that were perceived to be most positive and motivating made no mention of the word 'obesity' at all, and instead focused on making healthy behavioral changes without reference to body weight. These findings have important implications for framing messages in public health campaigns to address obesity, and suggest that certain types of messages may lead to increased motivation for behavior change among the public, whereas others may be perceived as stigmatizing and instill less motivation to improve health.

  8. Boletus edulis Nitrite Reductase Reduces Nitrite Content of Pickles and Mitigates Intoxication in Nitrite-intoxicated Mice.

    Science.gov (United States)

    Zhang, Weiwei; Tian, Guoting; Feng, Shanshan; Wong, Jack Ho; Zhao, Yongchang; Chen, Xiao; Wang, Hexiang; Ng, Tzi Bun

    2015-10-08

    Pickles are popular in China and exhibits health-promoting effects. However, nitrite produced during fermentation adversely affects health due to formation of methemoglobin and conversion to carcinogenic nitrosamine. Fruiting bodies of the mushroom Boletus edulis were capable of inhibiting nitrite production during pickle fermentation. A 90-kDa nitrite reductase (NiR), demonstrating peptide sequence homology to fungal nitrite reductase, was isolated from B. edulis fruiting bodies. The optimum temperature and pH of the enzyme was 45 °C and 6.8, respectively. B. edulis NiR was capable of prolonging the lifespan of nitrite-intoxicated mice, indicating that it had the action of an antidote. The enzyme could also eliminate nitrite from blood after intragastric administration of sodium nitrite, and after packaging into capsule, this nitrite-eliminating activity could persist for at least 120 minutes thus avoiding immediate gastric degradation. B. edulis NiR represents the first nitrite reductase purified from mushrooms and may facilitate subsequent applications.

  9. Public health and Plowshare

    Energy Technology Data Exchange (ETDEWEB)

    Terrill, Jr, J G [Consumer Protection and Environmental Health Service, U.S. PubIic Health Service, Washington, DC (United States)

    1969-07-01

    The protection of public health and safety is a principal area of concern in any application of nuclear energy. A health and safety analysis must be conducted and reviewed by appropriate agencies and the final results made available to interested agencies and groups, both public and private, prior to the application. This is especially important for the Plowshare Program - the peaceful uses of nuclear explosives - where the public is to be the ultimate beneficiary. Because public health must be a primary concern in the Plowshare Program, it is essential that the potential risk be weighed against the expected benefits to the public. Public health agencies must play an increasingly important role in the planning and operational stages of the peaceful applications of nuclear explosives and in the final stage of consumer use of Plowshare-generated products. There are many long term and long distance ramifications of the Plowshare Program, such a the potential radiological contamination of consumer products that may reach the consumer at long times after the event or at great distances from the site of the event. Criteria for evaluating public exposure to radiation from these products need to be developed based on sound scientific research. Standards for radioactivity in consumer products must be developed in relation to potential exposure of the public. Above all, a clear benefit to the public with a minimum of risk must be shown. The major purpose of this Symposium on the Public Health Aspects of Peaceful Uses of Nuclear-Explosives is to focus attention on the health and safety aspects, present the results of safety analyses accomplished to date and other information necessary to an understanding of the public health aspects, and to identify areas where additional research is required. A general overview of the total symposium content is presented with emphasis on the relationship of the topics to public health. (author)

  10. Public health and Plowshare

    International Nuclear Information System (INIS)

    Terrill, J.G. Jr.

    1969-01-01

    The protection of public health and safety is a principal area of concern in any application of nuclear energy. A health and safety analysis must be conducted and reviewed by appropriate agencies and the final results made available to interested agencies and groups, both public and private, prior to the application. This is especially important for the Plowshare Program - the peaceful uses of nuclear explosives - where the public is to be the ultimate beneficiary. Because public health must be a primary concern in the Plowshare Program, it is essential that the potential risk be weighed against the expected benefits to the public. Public health agencies must play an increasingly important role in the planning and operational stages of the peaceful applications of nuclear explosives and in the final stage of consumer use of Plowshare-generated products. There are many long term and long distance ramifications of the Plowshare Program, such a the potential radiological contamination of consumer products that may reach the consumer at long times after the event or at great distances from the site of the event. Criteria for evaluating public exposure to radiation from these products need to be developed based on sound scientific research. Standards for radioactivity in consumer products must be developed in relation to potential exposure of the public. Above all, a clear benefit to the public with a minimum of risk must be shown. The major purpose of this Symposium on the Public Health Aspects of Peaceful Uses of Nuclear-Explosives is to focus attention on the health and safety aspects, present the results of safety analyses accomplished to date and other information necessary to an understanding of the public health aspects, and to identify areas where additional research is required. A general overview of the total symposium content is presented with emphasis on the relationship of the topics to public health. (author)

  11. Strategi Public Relations dalam Mendukung Pemasaran Pembangkit Listrik Nasional (PLN

    Directory of Open Access Journals (Sweden)

    Novi Anggraeni

    2014-07-01

    Full Text Available Public relations is one of the elements that determine the viability of an organization positively. The purpose of the research; 1. Knowing the planning public relations strategies in support of marketing; 2. Knowing the kinds of public relations activities; 3. Knowing the packaging contents of the message of the communication media used; 4. Knowing the effect to be achieved; and 5. Knowing the obstacles faced. The method used descriptive qualitative. Results of the study are: 1. Judging from the background criteria for Public Relations of PT. PLN (Persero APJ Cirebon is formal education, job experience, appearance, skills, individual characteristics, and adaptation, credible communicator. 2. Kegiatan Public Relations to support the marketing of which the existence of a local radio talk show in Cirebon (Cirebon FM, a local television talk show in Cirebon (RCTV, cooperation in carrying out tasks related to corporate law. 3. Packaging persuasive message content, preparation of informative messages are intended to provide excitement and build consumer understanding. 4. The effect achieved a change in opinions, attitudes and behavior. 5. Barriers found limited use of communication media and the lack of communication superiors and subordinates

  12. The relationship between selenium and gastric cancer

    International Nuclear Information System (INIS)

    Shi Kuixiong; Ma Guansheng; Zhang Tingyu; Cheng Wufeng; Mao Dajuan; Pan Bixia; Xu Xiuxian

    1993-01-01

    Both sodium selenite and selenium yeast were chosen to block the MNNG mutagenesis. The inhibition rates were 66.5% and 37.9% respectively. The selenium levels in hair, serum and gastric juice, and the contents of nitrosamine in gastric juice were also determined. The results showed that the selenium levels were SG > CAG and Dys > GC (p CAG, Dyas and GC (p < 0.05). 19 cases of CAG patients treated with selenium yeast and 16 cases of the control were observed. After 10 weeks, the selenium levels in serum for the treated group were significantly increased. The symptoms of CAG patients seemed to be alleviated

  13. A Critical Analysis of the Library-Related Literature Concerning Censorship in Public Libraries and Public School Libraries in the United States during the 1980s.

    Science.gov (United States)

    Abbott, Randy L.

    This content analysis examines library science and education literature on censorship in public and public school libraries in the 1980s. The first chapter discusses the organization and activities of right-wing and left-wing pressure groups together with ways in which librarians have responded to their pressure. The distinction between censorship…

  14. Even in Public Television, Ownership Changes Matter.

    Science.gov (United States)

    Lashley, Marilyn E.

    1992-01-01

    Shows that executive turnover through four administrations (1967-89) has kept public broadcasting mired in budgetary crises, transforming its goals, structure, and programing content over time. Describes policy preferences imposed by administrators, identifies attendant modifications in organizational structure, and delineates effects of these…

  15. Neo-Nazis Sympathizers on the Forums of the Romanian Online Publications

    Directory of Open Access Journals (Sweden)

    Elena-Irina Macovei

    2013-08-01

    Full Text Available The research aims to highlight how the forums of the Romanian online publications may often become spaces for right-wing extremist propaganda. The case study includes about 1.000 comments of the readers, expressed on the articles about a protest of several intellectuals against a TV program of the Romanian public Television (TVR, where Corneliu Zelea Codreanu, the founder of the Iron Guard, a Nazi organization created in 1927, was presented as a romantic hero. The results of the content analysis of comments revealed the stigmatizing themes, the stereotypes and the extremist ideas identified on the forums of these articles. In addition, the comparison between the electronic platforms of the publications showed the importance of their features and of the characteristics of audiences regarding the content of the comments.

  16. Utilizing a Photo-Analysis Software for Content Identifying Method (CIM

    Directory of Open Access Journals (Sweden)

    Nejad Nasim Sahraei

    2015-01-01

    Full Text Available Content Identifying Methodology or (CIM was developed to measure public preferences in order to reveal the common characteristics of landscapes and aspects of underlying perceptions including the individual's reactions to content and spatial configuration, therefore, it can assist with the identification of factors that influenced preference. Regarding the analysis of landscape photographs through CIM, there are several studies utilizing image analysis software, such as Adobe Photoshop, in order to identify the physical contents in the scenes. This study attempts to evaluate public’s ‘preferences for aesthetic qualities of pedestrian bridges in urban areas through a photo-questionnaire survey, in which respondents evaluated images of pedestrian bridges in urban areas. Two groups of images were evaluated as the most and least preferred scenes that concern the highest and lowest mean scores respectively. These two groups were analyzed by CIM and also evaluated based on the respondent’s description of each group to reveal the pattern of preferences and the factors that may affect them. Digimizer Software was employed to triangulate the two approaches and to determine the role of these factors on people’s preferences. This study attempts to introduce the useful software for image analysis which can measure the physical contents and also their spatial organization in the scenes. According to the findings, it is revealed that Digimizer could be a useful tool in CIM approaches through preference studies that utilizes photographs in place of the actual landscape in order to determine the most important factors in public preferences for pedestrian bridges in urban areas.

  17. Development of an online tool for public health: the European Public Health Law Network.

    Science.gov (United States)

    Basak, P

    2011-09-01

    The European Public Health Law Network was established in 2007 as part of the European Union (EU) co-funded Public Health Law Flu project. The aims of the website consisted of designing an interactive network of specialist information and encouraging an exchange of expertise amongst members. The website sought to appeal to academics, public health professionals and lawyers. The Public Health Law Flu project team designed and managed the website. Registered network members were recruited through publicity, advertising and word of mouth. Details of the network were sent to health organizations and universities throughout Europe. Corresponding website links attracted many new visitors. Publications, news, events and a pandemic glossary became popular features on the site. Although the website initially focused only on pandemic diseases it has grown into a multidisciplinary website covering a range of public health law topics. The network contains over 700 publications divided into 28 public health law categories. News, events, front page content, legislation and the francophone section are updated on a regular basis. Since 2007 the website has received over 15,000 views from 156 countries. Newsletter subscribers have risen to 304. There are now 723 followers on the associated Twitter site. The European Public Health Law Network has been a successful and innovative site in the area of public health law. Interest in the site continues to grow. Future funding can contribute to a bigger site with interactive features and pages in a wider variety of languages to attract a wider global audience. Copyright © 2011 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  18. Content

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    secondary levels. In subject matter didactics, the question of content is more developed, but it is still mostly confined to teaching on lower levels. As for higher education didactics, discussions on selection of content are almost non-existent on the programmatic level. Nevertheless, teachers are forced...... curriculum, in higher education, and to generate analytical categories and criteria for selection of content, which can be used for systematic didactical reflection. The larger project also concerns reflection on and clarification of the concept of content, including the relation between content at the level......Aim, content and methods are fundamental categories of both theoretical and practical general didactics. A quick glance in recent pedagogical literature on higher education, however, reveals a strong preoccupation with methods, i.e. how teaching should be organized socially (Biggs & Tang, 2007...

  19. A Content Analysis of Cognitive Health Promotion in Popular Magazines

    Science.gov (United States)

    Friedman, Daniela B.; Laditka, Sarah B.; Laditka, James N.; Price, Anna E.

    2011-01-01

    Health behaviors, particularly physical activity, may promote cognitive health. The public agenda for health behaviors is influenced by popular media. We analyzed the cognitive health content of 20 United States magazines, examining every page of every 2006-2007 issue of the highest circulating magazines for general audiences, women, men, African…

  20. Bringing the Science of JWST to the Public

    Science.gov (United States)

    Green, Joel D.; Smith, Denise A.; Lawton, Brandon L.; Meinke, Bonnie K.; Jirdeh, Hussein

    2017-01-01

    The James Webb Space Telescope is the successor to the Hubble Space Telescope. STScI and the Office of Public Outreach are committed to bringing awareness of the technology, the excitement, and the future science potential of this great observatory to the public and to the scientific community, prior to its 2018 launch. The challenges in ensuring the high profile of JWST (understanding the infrared, the vast distance to the telescope's final position, and the unfamiliar science territory) requires us to lay the proper background, particularly in the area of spectroscopy. We currently engage the full range of the public and scientific communities using a variety of high impact, memorable initiatives, in combination with modern technologies to extend reach, linking the science goals of Webb to the ongoing discoveries being made by Hubble. Webbtelescope.org, the public hub for scientific information related to JWST, is now open. We have injected Webb-specific content into ongoing outreach programs: for example, partnering with high impact science communicators such as MinutePhysics to produce timely and concise content; partnering with musicians and artists to link science and art. Augmented reality apps showcase NASA’s telescopes in a format usable by anyone with a smartphone, and visuals from increasingly affordable 3D VR technologies.

  1. Influence of gamma irradiation of fission products of a research reactor on the stability of nitroso compounds

    Energy Technology Data Exchange (ETDEWEB)

    Mirna, A; Rau, G; Stark, W; Lock, O

    1982-10-01

    There is still a great deal of prejudice against using ionizing rays to treat foods. According to a report by the Joint FAO/IAEA/WHO Expert Committee of Food irradiation the irradiation of foods at a dose of up to 10 kGy (= 1 Mrd) is not regarded as a health hazard: the method is particularly recommended for treating spices and a number of other foods. The content of volatile nitrosamines (NA) can be reduced by the effects of gamma rays in a similar way to UV irradiation. A reduction in the NA content, although only limited, is regarded as a positive side effect of irradiation. The use of Cs-137, which accumulates when reconditioning the fuel elements of nuclear power plants, as a source of radiation may be of increasing interest in the future in view of efforts to save energy.

  2. Media framing and construction of childhood obesity: a content analysis of Swedish newspapers.

    Science.gov (United States)

    van Hooft, J; Patterson, C; Löf, M; Alexandrou, C; Hilton, S; Nimegeer, A

    2018-02-01

    Despite lower prevalence than most European countries, childhood obesity is a Swedish public health priority due to its lasting health impacts and socioeconomic patterning. Mass media content influences public and political perceptions of health issues, and media framing of childhood obesity may influence perceptions of its solutions. This study examines framing of childhood obesity in Swedish morning and evening newspapers from 1996 to 2014. Content analysis of 726 articles about childhood obesity published in the five most-circulated Swedish newspapers. Article content coded quantitatively and subjected to statistical analysis, describing relationships between themes and trends over time. Childhood obesity was consistently problematised, primarily in health terms, and linked to socio-economic and geographical factors. The yearly frequency of articles peaked in 2004, followed by a decline, corresponding with evidence about prevalence. Childhood obesity was framed as being driven by individual behaviours more frequently than structural or environmental factors. Structural framings increased over time, but constructions of the problem as driven by individual behaviours, particularly parenting, remained prominent. A relative growth in structural framings of causes and solutions over time, combined with prominent coverage of socio-economic inequalities, might be indicative of public and political amenability towards societal-level solutions, but individual behaviours remain prominent in framing of the issue. Health advocates might incorporate these insights into media engagement.

  3. Container-content compatibility studies: a pharmaceutical team's integrated approach.

    Science.gov (United States)

    Laschi, Alda; Sehnal, Natacha; Alarcon, Antoine; Barcelo, Beatrice; Caire-Maurisier, François; Delaire, Myriam; Feuilloley, Marc; Genot, Stéphanie; Lacaze, Catherine; Pisarik, Luc; Smati, Christophe

    2009-01-01

    Container-content compatibility studies are required as part of the submission of a new product market authorization file or for a change relating to the primary product-contact packaging. Many regulatory publications and guidances are available in the USA, Europe, and Japan. However these publications and guidances are not sufficiently precise enough to allow for consistent interpretation and implementation of the technical requirements. A working group has been formed by the French Society of Pharmaceutical Science and Technology (SFSTP) in order to propose guidance for container-content interaction studies that meet both European and US requirements, and allows consistent and standardized information to be presented by the industry to the regulators. When a pharmaceutical drug product remains in prolonged contact with a material, the two critical points to consider are the drug product's quality and safety. A pharmaceutical evaluation of the container-content relationship should be done based on the knowledge of the contact material (e.g., type, physicochemical properties), its manufacturing processes (e.g., the type of sterilization that could potentially alter the interactions), and the formulation components involved in contact with this material (e.g., physicochemical properties, pharmaceutical presentation, route of administration). Quality is evaluated using the stability study performed on the product. Safety is partially evaluated with the stability study and is analyzed in conjunction with toxicity testing, specifically with cytotoxicity testing. The toxicity aspect is the key point of the container-content compatibility study and of patient safety. Migration tests are conducted when an interaction is suspected, or found based on previous results, to identify the component responsible for this interaction and to help select a new material if needed. Therefore, such tests are perhaps not the best ones to use for the purpose of safety evaluation

  4. Methodological innovations in public health education: transdisciplinary problem solving.

    Science.gov (United States)

    Lawlor, Edward F; Kreuter, Matthew W; Sebert-Kuhlmann, Anne K; McBride, Timothy D

    2015-03-01

    In 2008, the faculty of the Brown School at Washington University in St. Louis designed a Master of Public Health program centered on transdisciplinary problem solving in public health. We have described the rationale for our approach, guiding principles and pedagogy for the program, and specific transdisciplinary competencies students acquire. We have explained how transdisciplinary content has been organized and delivered, how the program is being evaluated, and how we have demonstrated the feasibility of this approach for a Master of Public Health degree.

  5. Public infrastructure investment: A bridge to productivity growth?

    OpenAIRE

    Jerome Levy Economics Institute of Bard College

    1993-01-01

    Table of Contents: Preface, by Dimitri B. Papadimitriou; Public Capital and Economic Growth, by David Alan Aschauer; New Federal Spending for Infrastructure: Should We Let This Genie Out of the Bottle?, by Douglas Holtz-Eakin. Abstract: This brief presents contrasting views on the effects of public infrastructure investment on private sector productivity. David Alan Aschauer states that the slower rate of productivity growth since the early 1970s-coupled with an aging population, the declinin...

  6. Elite Polarization and Public Opinion

    DEFF Research Database (Denmark)

    Robison, Joshua; Mullinix, Kevin

    2016-01-01

    Elite polarization has reshaped American politics and is an increasingly salient aspect of news coverage within the United States. As a consequence, a burgeoning body of research attempts to unravel the effects of elite polarization on the mass public. However, we know very little about how...... polarization is communicated to the public by news media. We report the results of one of the first content analyses to delve into the nature of news coverage of elite polarization. We show that such coverage is predominantly critical of polarization. Moreover, we show that unlike coverage of politics focused...... on individual politicians, coverage of elite polarization principally frames partisan divisions as rooted in the values of the parties rather than strategic concerns. We build on these novel findings with two survey experiments exploring the influence of these features of polarization news coverage on public...

  7. When public service drama travels

    DEFF Research Database (Denmark)

    Jensen, Pia Majbritt; Nielsen, Jakob Isak; Waade, Anne Marit

    2016-01-01

    the last 15 years, our empirical data also show significant new patterns in production culture and international market orientation within DR. Interestingly, however, our study demonstrates the distinctive contribution that precisely DR’s public service remit has made to the quality of its drama......This article provides a detailed analysis of how the Danish public service broadcaster DR employs external funding for its drama productions. This investigation is carried out in order to discuss the schisms involved when a public service broadcaster – whose traditional obligations arguably pertain...... to the national sphere – becomes a player in the international market for television content and, as a consequence, becomes partly reliant on international funding. Our article examines five different forms of external funding (i.e. funding from sources other than DR’s licence fee income): (1) co...

  8. Content of teachers' stereotypes about adolescents

    Directory of Open Access Journals (Sweden)

    Đerić Ivana

    2009-01-01

    Full Text Available Discourse on 'problematic behavior' of the young in adolescence period is often present in lay, media, professional and scientific public. In this research, we performed empirical testing of the psychological concept of 'storm and stress', which is manifested by stereotypes about adolescents as rebels. The goal was to establish whether teachers hold stereotypes about younger adolescents as a social group and what the content of the stereotype is. Research participants were 193 teachers teaching the seventh grade in ten Belgrade primary schools. Factor analysis method established the presence of several factors, which reflect the psychological content and meaning of teachers' stereotypes about younger adolescents. The results of our research point out: (a that stereotypes of teachers about younger adolescents stand in partial correspondence with the content of a widely distributed concept of 'storm and stress'; (b that this concept is mostly loaded with a negative perception of pupils on the part of teachers and (c that teachers less often perceive pupils through the prism of some positive qualities. That is, teachers think that these positive qualities are not 'typical' qualities of adolescents if they are observed as a group. Interviewed teachers hold stereotypes about younger adolescents, but intensity and valence of stereotypes vary depending on the nature of obtained factors.

  9. Is Public Relations Research Providing the Unified Body of Knowledge Necessary for Professional Status?

    Science.gov (United States)

    Gaudino, James L.; Steele, Michael E.

    To investigate whether researchers are developing empirically-based public relations research efforts, and whether such efforts could be considered useful to public relations practitioners, a study conducted a content analysis of all articles published in "Public Relations Review" from 1977 through 1987. Articles (196 were coded in all)…

  10. Phenology Atlas of Czechia in preparation - aim & content

    Science.gov (United States)

    Hajkova, L.; Nekovar, J.; Novak, M.; Richterova, D.

    2009-09-01

    The main task is to create Phenology Atlas of Czechia for the period 1991 - 2010 by using geographic information systems. The general outputs will be maps (average phenophase onset at different altitudes), graphs (evaluation of phenophase onset in time) and tables (statistical results) with text, picture and botanical specification. The publication will be divided into 6 main chapters (Introduction, Phenology in Czechia & Europe, Methodology of observation, Field crops & Fruit trees & Wild plants, Phenology regionalisation, Temporal and Spatial variability). The essantial emphasis will be enforced on wild plants especially allergology important plants and phenophases. CHMI phenological and meteorological data will be used as an input data. This publication will be allocated for general public, supposed size B4, 270 - 300 pages. The research project is proposed for 3 years (2009 - 2011). In the presentation will be given several examples of Atlas content (Norway Spruce and Birch phenophases from Transaction of CHMI Nr.50, 2007).

  11. Public Reporting and a More Sustainable Army

    Science.gov (United States)

    2009-04-01

    Coca - Cola Yes Microsoft Yes International Business Machines (IBM) Yes General Electric (GE) Yes Nokia Yes Toyota Yes Intel Yes McDonald’s Yes...DISCLAIMER: The contents of this report are not to be used for advertising , publication, or promotional purposes. Citation of trade names does not

  12. Aboriginal and Torres Strait Islander public health: online and integrated into core Master of Public Health subjects

    Directory of Open Access Journals (Sweden)

    Lynnell Angus

    2016-04-01

    Full Text Available The Master of Public Health (MPH is an internationally recognised post-graduate qualification for building the public health workforce. In Australia, MPH graduate attributes include six Indigenous public health (IPH competencies. The University of Melbourne MPH program includes five core subjects and ten specialisation streams, of which one is Indigenous health. Unless students complete this specialisation or electives in Indigenous health, it is possible for students to graduate without attaining the IPH competencies. To address this issue in a crowded and competitive curriculum an innovative approach to integrating the IPH competencies in core MPH subjects was developed. Five online modules that corresponded with the learning outcomes of the core public health subjects were developed, implemented and evaluated in 2015. This brief report outlines the conceptualisation, development, and description of the curriculum content; it also provides preliminary student evaluation and staff feedback on the integration project.

  13. Resource file: practical publications for energy management, edition III

    Energy Technology Data Exchange (ETDEWEB)

    1980-03-01

    The Resource File is an in-depth bibliography of 166 practical and action-oriented energy conservation publications and materials. It is a reference tool, designed for Federal, state, and local energy managers or people who are asked to recommend how-to conservation guides to the public. Each listing describes a publication's intended audience and provides a summary of its contents. Included are operations and maintenance manuals, life-cycle costing handbooks, home insulation manuals, films on fuel-saving driving techniques, and courses devoted exclusively to home weatherization. 166 items.

  14. Impact of Online User-Generated Content on Retailers and Manufacturers

    Science.gov (United States)

    Kwark, Young

    2013-01-01

    Online user-generated content has been ubiquitous. Consumers are eager to not only listen to the other consumers but provide opinion to the public. The former reduces the consumers' uncertainty about products and the latter reduces the firms' uncertainty about consumers. We examine the effect of online product reviews, a most common form of…

  15. Multimedia content classification metrics for content adaptation

    OpenAIRE

    Fernandes, Rui; Andrade, M.T.

    2015-01-01

    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  16. Multimedia content classification metrics for content adaptation

    OpenAIRE

    Fernandes, Rui; Andrade, M.T.

    2016-01-01

    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  17. Regulating Alcohol Advertising: Content Analysis of the Adequacy of Federal and Self-Regulation of Magazine Advertisements, 2008–2010

    Science.gov (United States)

    Cukier, Samantha; Jernigan, David H.

    2014-01-01

    Objectives. We analyzed beer, spirits, and alcopop magazine advertisements to determine adherence to federal and voluntary advertising standards. We assessed the efficacy of these standards in curtailing potentially damaging content and protecting public health. Methods. We obtained data from a content analysis of a census of 1795 unique advertising creatives for beer, spirits, and alcopops placed in nationally available magazines between 2008 and 2010. We coded creatives for manifest content and adherence to federal regulations and industry codes. Results. Advertisements largely adhered to existing regulations and codes. We assessed only 23 ads as noncompliant with federal regulations and 38 with industry codes. Content consistent with the codes was, however, often culturally positive in terms of aspirational depictions. In addition, creatives included degrading and sexualized images, promoted risky behavior, and made health claims associated with low-calorie content. Conclusions. Existing codes and regulations are largely followed regarding content but do not adequately protect against content that promotes unhealthy and irresponsible consumption and degrades potentially vulnerable populations in its depictions. Our findings suggest further limitations and enhanced federal oversight may be necessary to protect public health. PMID:24228667

  18. A roughly mapped terra incognita: Image of the child in adult-oriented media contents

    Directory of Open Access Journals (Sweden)

    Korać Nada M.

    2003-01-01

    Full Text Available The study analyzes the image of the child in the media contents intended for adult audiences in Serbia, considering the importance of the role media play in shaping public opinion on children, as well as the influence of such public opinion on adults' attitudes, decisions and actions concerning children. The study focuses on visibility and portrayal of children in the media, in order to determine to what extent children are present in them, and in what way. Relevant data were collected for three media - press, radio and television - mostly covering the entire territory of Serbia, over two consecutive months (April - May 2001. Content analysis revealed that children are not only underrepresented, but also misrepresented, in Serbian media.

  19. Publications of GANIL interdisciplinary researches 1983-2012

    International Nuclear Information System (INIS)

    2012-01-01

    After a brief presentation of some statistical information on the content and evolution of research topics during the period ranging from 1983 to 2012, this publication proposes a list of the numerous publications issued by the GANIL, a group of interdisciplinary researches. These publications addressed the following themes: atomic spectroscopy, physics of atomic collisions, physics of molecular collisions, ion transport in solids, duct, electron emission, pulverization, surface modification, effects in amorphous materials, effects in metals, effects in semiconductors, effects in superconductors, effects in oxides and carbides, effects in ionic crystals, effects in polymers, radiolysis at high linear energy transfer, radio-biology, nano materials and nano structuration, applications, miscellaneous topics, accreditation to supervise researches, research thesis

  20. [Pedagogical training in stricto sensu graduate programs in public health].

    Science.gov (United States)

    Corrêa, Guilherme Torres; Ribeiro, Victoria Maria Brant

    2013-06-01

    The scope of this research is to discuss the relevance and need for pedagogical training of university lecturers in the Public Health field. The contention is that college teaching is a practice that requires specific training, since it is characterized by complex elements that transcend the mastery of given content. Considering stricto sensu graduate studies as an important stage in the training of future university lecturers, an attempt was made to identify and analyze the subjects and practices of pedagogical training in academic masters and doctorate programs in Public Health. To achieve the research aim, this work was based on Pierre Bourdieu's field theory and on Tomaz Tadeu da Silva's curriculum theory. Results indicate that the programs do not consider the aspect of teacher training as a major issue. With regard to the Public Health field approximately 61% of masters and 38% of doctorate programs have pedagogical training subjects/practices. Furthermore, there is a tendency for technical-instrumental training, which is in line with the history of the Public Health field. The conclusion is that there is a need to develop a culture that values college and graduate Public Health teaching, considering the complexity of pedagogical practice in all its dimensions.

  1. Surfing the net for public health resources.

    Science.gov (United States)

    Angell, C; Hemingway, A; Hartwell, H

    2011-08-01

    To identify public health open educational resources (OER) available online, map the identified OER to The Public Health Skills and Career Framework (PHSCF), and triangulate these findings with public health practitioners. Systematic online search for public health OER. An online search was undertaken using a pre-defined set of search terms and inclusion/exclusion criteria. Public health OER were then mapped against the UK PHSCF. The findings of the search were discussed with public health specialists to determine whether or not they used these resources. A number of public health OER were identified, located on 42 websites from around the world. Mapping against the UK PHSCF demonstrated a lack of coverage in some areas of public health education. It was noted that many of the OER websites identified were not those generally used in practice, and those sites preferred by public health specialists were not identified by the online search. Public health OER are available from a number of providers, frequently universities and government organizations. However, these reflect a relatively small pool of original OER providers. Tagging of websites does not always identify their public health content. In addition, users of public health OER may not use search engines to identify resources but locate them using other means. Copyright © 2011 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  2. Selected DOE Headquarters publications, October 1977-September 1979

    International Nuclear Information System (INIS)

    1979-11-01

    This sixth issue of cumulative listings of DOE Headquarters publications covers the first two years of the Department's operation (October 1, 1977 - September 30, 1979). It lists two groups of publications issued by then-existing Headquarters organizations and provides an index to their title keywords. The two groups of publications are publications assigned a DOE/XXX-type report number code and Headquarters contractor reports prepared by contractors (and published by DOE) to describe research and development work they have performed for the Department. Certain publications are omitted. They include such items as pamphlets, fact sheets, bulletins, newsletters, and telephone directories, as well as headquarters publications issued under the DOE-tr (DOE translation) and CONF (conference proceedings) codes, and technical reports from the Jet Propulsion Laboratory and NASA issued under DOE/JPL and DOE/NASA codes. The contents of this issue will not be repeated in subsequent issues of DOE/AD-0010

  3. Public gambling policy : the need for gambling market segmentation

    OpenAIRE

    Grebliauskas, Artūras

    2011-01-01

    Gambling services market is characterized by their complexity: they contain private and public goods characteristics, external effects and are politically sensitive. Therefore, understanding the contents of these services is necessary for the effective delivery of public gambling policy. Lithuanian gambling market can be distinguished according the following types of market structure: 1) Monopolistic competition – a category B slot parlors and 2) Oligopoly – betting, casinos, and 3) A natural...

  4. Is electricity a public good?

    International Nuclear Information System (INIS)

    Salies, Evens; Kiesling, Lynne; Giberson, Michael

    2007-04-01

    Wholesale electricity markets are increasingly driven by the rules of competition while recent outages in different regions of the world suggest that security of supply is a public good. The objective of this paper is to show that security of supply and more generally, electricity supply has both public and private characteristics. Whilst the public good characteristic explains why some producers may prefer to free ride on others' investments to maintain reliability, the private good aspect of reliability shows that agents may have a variety of preferences for reliability. Then by relying on the concept of Pareto-relevant externality, the paper explores the private aspect of reliability for the prospect of creating and selling reliability as a differentiated product complementary to bulk power markets. Finally, policy recommendations are derived that aim to enhance information content in the network. Initially published in 'Revue de l'OFCE' No. 101

  5. Cigarette smoke chemistry market maps under Massachusetts Department of Public Health smoking conditions.

    Science.gov (United States)

    Morton, Michael J; Laffoon, Susan W

    2008-06-01

    This study extends the market mapping concept introduced by Counts et al. (Counts, M.E., Hsu, F.S., Tewes, F.J., 2006. Development of a commercial cigarette "market map" comparison methodology for evaluating new or non-conventional cigarettes. Regul. Toxicol. Pharmacol. 46, 225-242) to include both temporal cigarette and testing variation and also machine smoking with more intense puffing parameters, as defined by the Massachusetts Department of Public Health (MDPH). The study was conducted over a two year period and involved a total of 23 different commercial cigarette brands from the U.S. marketplace. Market mapping prediction intervals were developed for 40 mainstream cigarette smoke constituents and the potential utility of the market map as a comparison tool for new brands was demonstrated. The over-time character of the data allowed for the variance structure of the smoke constituents to be more completely characterized than is possible with one-time sample data. The variance was partitioned among brand-to-brand differences, temporal differences, and the remaining residual variation using a mixed random and fixed effects model. It was shown that a conventional weighted least squares model typically gave similar prediction intervals to those of the more complicated mixed model. For most constituents there was less difference in the prediction intervals calculated from over-time samples and those calculated from one-time samples than had been anticipated. One-time sample maps may be adequate for many purposes if the user is aware of their limitations. Cigarette tobacco fillers were analyzed for nitrate, nicotine, tobacco-specific nitrosamines, ammonia, chlorogenic acid, and reducing sugars. The filler information was used to improve predicting relationships for several of the smoke constituents, and it was concluded that the effects of filler chemistry on smoke chemistry were partial explanations of the observed brand-to-brand variation.

  6. Is the low level of physical activity a public policy issue?

    Directory of Open Access Journals (Sweden)

    Kalman Michal

    2013-03-01

    Full Text Available BACKGROUND: Many studies and scientific evidence confirm a positive effect of physical activity on the quality of life and human health. Physical activity, which is also one of the key factors preventing mass non-communicable diseases, is decreasing in Europe, including the Czech Republic, both in children and adults. Serious health consequences for the population and economy of the countries are a reason for a discussion about including the low level of physical activity among public policy issues and a higher allocation of public sources into the area of physical activity promotion. OBJECTIVES: The main objective of the paper is to determine whether the low level of physical activity is a public policy issue. An issue that should by systematically addressed by national, regional as well as local policy. METHODS: Through the policy analysis approach we conducted a content analysis of 25 systematically selected foreign national strategies aimed at the issue of physical activity promotion. The data source was an internal database of the World Health Organization - the International Inventory of Documents on Physical Activity Promotion. The content analysis of the strategies was performed using the Atlas.ti software tool. RESULTS: During a content analysis of 25 foreign strategies a total of 411 text segments (quotations relating to the low level of physical activity were selected. These text segments showed five basic features of a public policy issue according to a conceptual framework developed by Bardach (2000 and Patton and Sawicky (1993 - 1 affects the lives of a significant number of people of a society; 2 is analysable; 3 can be solved through public policy tools; 4 the primary cause or problem can be defined; 5 cannot be solved easily and quickly. CONCLUSIONS: The results indicate that the low level of physical activity is a public policy issue that must be systematically addressed at national level.

  7. Creative communication in public relations activities

    Directory of Open Access Journals (Sweden)

    Dalibor Jakus

    2013-12-01

    Full Text Available This article discusses several approaches to new waves of public relations. Emphasis is given to the creative impulse since many public relations professionals are less familiar with it than other forms of communication. Five criteria are suggested for structuring creative communications: 1. learning how to be a good storyteller; 2. visual communication is the content that could increasingly build strong relationships with audiences; 3. the PR practitioner’s challenge is to evaluate what people are discussing and identify the recurring issues in their marketplace; 4. recognizing that local is new global; and 5. predicate that PR is constantly changing. People who work in public relations possess the skill of offering arguments that will convince the people themselves of something. However, these skills can be offered in traditional or creative forms of expression. If we define public relations as the management of an organization’s communication with its public, then we are referring to the traditional dimension of public relations, the basis and ultimate goal of which are to cultivate relationships with the participants of the process in order to obtain support and to build trust and reputation.

  8. Public and media attitudes to nuclear power in Italy

    International Nuclear Information System (INIS)

    Belelli, U.

    1988-01-01

    A study carried out by the Italian Electricity Board on the public acceptability of nuclear power, is reported. The question was examined in two ways. A sociological analysis was carried out with the aim of understanding the behaviour of public opinion. The results revealed that individual attitudes towards nuclear power are based on cost-benefit evaluations assessed in terms of social parameters by an instinctive rather than a rational process. Secondly press articles before and after the Chernobyl accident were analysed in terms of both the message being communicated and the quality of the technical content. Characteristics of the press coverage were more stress on nuclear safety after Chernobyl leading to greater opposition to nuclear power in general, a tendency for comment to dominate over factual information and no proper evaluation of the technical content. The major overall conclusions drawn are the need for international cooperation to address the social implications of the nuclear question, and for effective communication of information on power plant safety both to expert social and political bodies and, in a popular version, to the general public. (U.K.)

  9. CONTENT MANAGEMENT SYSTEM FOR EDUСATIONAL SITES

    Directory of Open Access Journals (Sweden)

    Natalia T. Zadorozhna

    2010-08-01

    Full Text Available Technological aspects of Content Management System (CMS-system, developed by the Internet-center of education branch are analysed in the article. As well as CMS-system for site "PCERU" (Public Council of Education and Researchers of Ukraine, portal of the State National Pedagogical Library of Ukraine V.O. Sukhomlinskogo, methodological and technological aspects of creation of the electronic version of scientifically-methodical magazine «The Ukrainian language and the literature at school» Institute of pedagogics of APS of Ukraine are described.

  10. Art as Resistance: Creating and Collecting Content for a Public Lesson on Standardization

    Science.gov (United States)

    Smith, Becky L. Noël; Shaw, Michael L.

    2014-01-01

    The negative emotional affects of standardized teaching and learning abound in public schools and work to create a melancholic, shared reality for teachers and students. The authors argue that teachers and students must acknowledge this melancholy and pursue shared inquiry around those emotions in order to help bring about understanding and the…

  11. Content Analysis of Research Trends in Instructional Design Models: 1999-2014

    Science.gov (United States)

    Göksu, Idris; Özcan, Kursat Volkan; Çakir, Recep; Göktas, Yuksel

    2017-01-01

    This study examines studies on instructional design models by applying content analysis. It covers 113 papers published in 44 international Social Science Citation Index (SSCI) and Science Citation Index (SCI) journals. Studies on instructional design models are explored in terms of journal of publication, preferred model, country where the study…

  12. Theological ethics, moral philosophy, and public moral discourse.

    Science.gov (United States)

    Jonsen, Albert R

    1994-03-01

    The advent and growth of bioethics in the United States in the late 1960s and early 1970s precipitated an era of public moral discourse, that is, the deliberate attempt to analyze and formulate moral argument for use in public policy. The language for rational discussion of moral matters evolved from the parent disciplines of moral philosophy and theological ethics, as well as from the idioms of a secular, pluralistic world that was searching for policy answers to difficult bioethical questions. This article explores the basis and content of the unique contributions of both theological and philosophical ethics to the development of public moral discourse.

  13. Research Agendas and Pedagogical Applications: What "Public Relations Review" Tells Us.

    Science.gov (United States)

    Thomsen, Steven R.

    A study explored the research agenda of "Public Relations Review," the oldest scholarly journal in the public relations field. To provide a descriptive and inferential analysis of the content of the journal from 1985 to 1994, four volumes were selected at random (1985, 1987, 1991, and 1993) and all the articles in them were analyzed.…

  14. Educating the future public health workforce: do schools of public health teach students about the private sector?

    Science.gov (United States)

    Rutkow, Lainie; Traub, Arielle; Howard, Rachel; Frattaroli, Shannon

    2013-01-01

    Recent surveys indicate that approximately 40% of graduates from schools of public health are employed within the private sector or have an employer charged with regulating the private sector. These data suggest that schools of public health should provide curricular opportunities for their students--the future public health workforce--to learn about the relationship between the private sector and the public's health. To identify opportunities for graduate students in schools of public health to select course work that educates them about the relationship between the private sector and public health. We systematically identified and analyzed data gathered from publicly available course titles and descriptions on the Web sites of accredited schools of public health. Data were collected in the United States. The sample consisted of accredited schools of public health. Descriptions of the number and types of courses that schools of public health offer about the private sector and identification of how course descriptions frame the private sector relative to public health. We identified 104 unique courses with content about the private sector's relationship to public health. More than 75% of accredited schools of public health offered at least 1 such course. Nearly 25% of identified courses focused exclusively on the health insurance industry. Qualitative analysis of the data revealed 5 frames used to describe the private sector, including its role as a stakeholder in the policy process. Schools of public health face a curricular gap, with relatively few course offerings that teach students about the relationship between the private sector and the public's health. By developing new courses or revising existing ones, schools of public health can expose the future public health workforce to the varied ways public health professionals interact with the private sector, and potentially influence students' career paths.

  15. An Analysis of Televised Public Service Advertising. Drug Abuse Information Research Project.

    Science.gov (United States)

    Hanneman, Gerhard J.; And Others

    Government regulations state that broadcasters are obligated to allot program time to matters of public interest, but neither law nor precedent have determined their commitment to present messages on social problems. To determine the amount of public service advertising (PSA) that is broadcast, particularly anti-drug appeals, a content analysis…

  16. Selected DOE Headquarters publications, October 1977-September 1979

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-11-01

    This sixth issue of cumulative listings of DOE Headquarters publications covers the first two years of the Department's operation (October 1, 1977 - September 30, 1979). It lists two groups of publications issued by then-existing Headquarters organizations and provides an index to their title keywords. The two groups of publications are publications assigned a DOE/XXX-type report number code and Headquarters contractor reports prepared by contractors (and published by DOE) to describe research and development work they have performed for the Department. Certain publications are omitted. They include such items as pamphlets, fact sheets, bulletins, newsletters, and telephone directories, as well as headquarters publications issued under the DOE-tr (DOE translation) and CONF (conference proceedings) codes, and technical reports from the Jet Propulsion Laboratory and NASA issued under DOE/JPL and DOE/NASA codes. The contents of this issue will not be repeated in subsequent issues of DOE/AD-0010. (RWR)

  17. A Study on Volunteers of the Storytelling of Training in Public Libraries: A Case Study on Volunteer Storyteller of Taipei Public Library

    Directory of Open Access Journals (Sweden)

    Yu-Ping Peng

    2017-03-01

    Full Text Available In recent years, the administrators of public library administrators have been actively promoting children’s reading services. In particular, storytelling activities have a significantly positive effect on enhancing children’s interest and ability in reading. Because of human resource shortages at public libraries, providing these services depends on volunteers. The public libraries should enhance the competencies of volunteers who engage in storytelling, and provide appropriate training for maintaining as well as improving the effectiveness of storytelling services. Therefore, this study was conducted to examine the storytelling training of storytelling volunteers. The study used in-depth interviews to obtain information on the experiences, ideas, and suggestions of public library storytelling volunteers at Taipei Public Library. Current education and training of storytelling volunteer encompasses demand analysis, implementation methods, course content, assessment of effectiveness, and suggestions for adjusting education and training in public library. Finally, the present study results are provided for education and training of storytelling volunteers for public libraries.

  18. Content and ratings of teen-rated video games.

    Science.gov (United States)

    Haninger, Kevin; Thompson, Kimberly M

    2004-02-18

    Children's exposure to violence, blood, sexual themes, profanity, substances, and gambling in the media remains a source of public health concern. However, content in video games played by older children and adolescents has not been quantified or compared with the rating information provided to consumers by the Entertainment Software Rating Board (ESRB). To quantify and characterize the content in video games rated T (for "Teen") and to measure the agreement between the content observed in game play and the ESRB-assigned content descriptors displayed on the game box. We created a database of all 396 T-rated video game titles released on the major video game consoles in the United States by April 1, 2001, to identify the distribution of games by genre and to characterize the distribution of ESRB-assigned content descriptors. We randomly sampled 80 video game titles (which included 81 games because 1 title included 2 separate games), played each game for at least 1 hour, quantitatively assessed the content, and compared the content we observed with the content descriptors assigned by the ESRB. Depictions of violence, blood, sexual themes, gambling, and alcohol, tobacco, or other drugs; whether injuring or killing characters is rewarded or is required to advance in the game; characterization of gender associated with sexual themes; and use of profanity in dialogue, lyrics, or gestures. Analysis of all content descriptors assigned to the 396 T-rated video game titles showed 373 (94%) received content descriptors for violence, 102 (26%) for blood, 60 (15%) for sexual themes, 57 (14%) for profanity, 26 (7%) for comic mischief, 6 (2%) for substances, and none for gambling. In the random sample of 81 games we played, we found that 79 (98%) involved intentional violence for an average of 36% of game play, 73 (90%) rewarded or required the player to injure characters, 56 (69%) rewarded or required the player to kill, 34 (42%) depicted blood, 22 (27%) depicted sexual themes

  19. Considerations in the public acceptance of sewage sludge irradiation systems

    International Nuclear Information System (INIS)

    Dix, G.P.

    1975-01-01

    Considerations associated with public acceptance of municipal sewage sludge irradiation systems are discussed including the benefit to society, public information and safeguards. Public acceptance of products is based upon the benefit to society as measured by reduced consumer costs, minimization of public risk and enhancement of the quality of life and the environment. When viewed in this positive light, the sludge irradiator has high potential benefits to the community. If large-scale engineering experiments show that sludge irradiation is more cost-effective than other methods, reduced consumer costs would result. Today many sewage plants do not consistently remove pathogens from sludge; sludge irradiation could be an effective method of pathogen removal and result in avoidance of a major public risk. The sludge irradiator may be able to clean up recreational areas, reduce noxious odours from sewage treatment facilities, and reduce the energy requirements for producing fertilizer and soil conditioners and conserve their mineral content. Plant safeguards must be explained to dispel public concern that the contents of the source can be released to the sludge accidentally. This will be the main issue within the technical sector of the public, and the design, procedural and administrative safeguards of the plant must be fully explained. The primary risk associated with sludge irradiators will be the remote possibility of source leakage into the sludge. The various safeguards in sludge irradiation plants are discussed in detail including the form of the radionuclide, encapsulation, the irradiation chamber, safeguards instrumentation, shielding and thermal safeguards. (Author)

  20. Public inquiries in Canada

    International Nuclear Information System (INIS)

    Bourque, D.

    1992-01-01

    The Canadian Constitution provides that the provinces may exclusively make laws in relation to electrical generation facilities. However through the exercise of its declaratory power, which is an exceptional power assigned to the federal Parliament, the latter has assumed exclusive legislative jurisdiction over the nuclear fuel cycle. Thus, the legislation applying to nuclear power plants is that which is passed by the federal Parliament. On June 18, 1990, the Canadian government tabled Bill C-78 (Environmental Assessment Act), which clarifies the nature, purpose and scope of public hearings into the construction of nuclear power plants. These reflections upon the role of the public hearing in the Canadian context lead to more general observations on the need to restructure decision-making mechanisms in order to take into account new values that important segments of the population are espousing. More open and democratic decision-making mechanisms, both for developing the content of energy policies and reviewing the construction of specific projects, constitute one of the avenues that should be explored in order to arrive at better public understanding and acceptance of nuclear energy. Public hearings can play an important role in this restructuring of decision-making mechanisms. Precise rules must nevertheless be established in order to use this means effectively and to avoid raising false expectations. (author)

  1. On the Creative Edge: Exploring Motivations for Creating Non-Suicidal Self-Injury Content Online.

    Science.gov (United States)

    Seko, Yukari; Kidd, Sean A; Wiljer, David; McKenzie, Kwame J

    2015-10-01

    The last decade has witnessed an exponential growth in user-generated online content featuring Non-Suicidal Self-Injury (NSSI), including photography, digital video, poems, blogging, and drawings. Although the increasing visibility of NSSI content has evoked public concern over potential health risks, little research has investigated why people are drawn to create and publish such content. This article reports the findings from a qualitative analysis of online interviews with 17 individuals who produce NSSI content. A thematic analysis of participants' narratives identified two prominent motives: self-oriented motivation (to express self and creativity, to reflect on NSSI experience, to mitigate self-destructive urges) and social motivation (to support similar others, to seek out peers, to raise social awareness). Participants also reported a double-edged impact of NSSI content both as a trigger and a deterrent to NSSI. © The Author(s) 2015.

  2. Corporate social responsibility as a part of corporate public relations in Serbia

    Directory of Open Access Journals (Sweden)

    Vuković Andrea

    2016-01-01

    Full Text Available Besides the media, the web presentations of the companies are one of the possible and widely applied means for communication of corporate social responsibility (CSR. For efficient CSR communication, good planning of the massages that will be presented to the public is of particular importance. It is additionally emphasized in the countries in the transition period where the social environment is burdened with numerous problems that result in pre­formed public mistrust towards companies. The extent and the results of public cognition of the company and creation of its identity and image are highly dependent from content of the web presentation but also of the manner of presentation and positioning of specific contents. Application of adequate slogans, can also highly contribute to the visibility of specific information. In order to review the way in which companies in Serbia present their CSR motives and activities, the web pages of leading companies in Serbia from the agro-business, public and financial sectors were analyzed and the practice of presentation of CSR to the public was reviewed. The similarities and differences in approach to CSR communication among analyzed sectors are outlined in the research results.

  3. The public communication of science in public health graduate programs in Brazil: From the coordinators' perspective

    Science.gov (United States)

    Teixeira, C. A.; Gallo, P. R.

    2014-12-01

    Introduction - The elaboration process of public policies for science and technology in knowledge societies should include not only experts, but all society members. There are studies on lay people's perception of science and technology. However, what is the scientists' perspective on public communication of science? Objectives - To describe and characterize the concepts that coordinators of Brazilian public health graduate programs have about public communication of science. Methods - This is an analytical and descriptive report of an exploratory research (doctoral study). The answers of fifty-one coordinators to two questionnaires were submitted for content analysis. The categories were transformed into variables that allowed the data processing by the Hiérarchique Classificatoire et Cohésitive (CHIC®) software. Results - Similarity analysis strongly suggested (0,99) that coordinators understand public communication as a communication directed to academic peers and students, also as a form of participation in scientific events and communication by scientific papers. Likewise, the implication analysis suggested a strong implication (0,98) between scientific communication understood as public communication. Conclusion - The notion of public communication of science as a social right and as a commitment and responsibility of researchers and research centers is not explicitly present in the narrative of the coordinators, although in general the coordinators conceive it as a relevant activity. This study thus contributes to a reflection on the role of scientists, researchers and research centers in public communication of science and technology.

  4. Defining the public, defining sociology: hybrid science-public relations and boundary-work in early American sociology.

    Science.gov (United States)

    Evans, Michael S

    2009-01-01

    In this paper, I examine how scientific disciplines define their boundaries by defining the publics with whom they engage. The case study is an episode in the development of early American sociology. In response to the dual challenge of credibility set up by the conflict between religious Baconian science and secular positivist science, key actors engaged in specific strategies of boundary-work to create their desired "sociological public"--a hybrid form of science-public relations that appealed to hostile university scientists while excluding a supportive religious audience from participation in the production of scientific knowledge. Using this case, I offer two specific insights. First I illustrate how, in the pursuit of scientific credibility, actors engage in boundary-work to differentiate audiences, not just practitioners. Such defining of publics is constitutive of scientific disciplines in their formative stage. Second, I demonstrate how audience boundaries can be redefined through the capture of existing boundary objects. Specifically, the removal of informational content in key boundary objects creates durable boundaries that are difficult to overcome.

  5. Facebook and Public Health

    DEFF Research Database (Denmark)

    Straton, Nadiya; Vatrapu, Ravi; Mukkamala, Raghava Rao

    2017-01-01

    This paper reports on a survey about the perceptions and practices of social media managers and experts in the area of public health. We have collected Facebook data from 153 public health care organizations and conducted a survey on them. 12% of organizations responded to the questionnaire....... The survey results were combined with the findings from our previous work of applying clustering and supervised learning algorithms on big social data from the official Facebook walls of these organizations. In earlier research, we showed that the most successful strategy that leads to higher post engagement...... is visual content. In this paper, we investigated if organisations pursue this strategy or some other strategy that was successful and has not been uncovered by the machine learning algorithms. Performance of each organisation on Facebook is based on the number of posts (volume share) and the number...

  6. Publication trends in neuroimaging of minimally conscious states

    Directory of Open Access Journals (Sweden)

    Alex Garnett

    2013-09-01

    Full Text Available We used existing and customized bibliometric and scientometric methods to analyze publication trends in neuroimaging research of minimally conscious states and describe the domain in terms of its geographic, contributor, and content features. We considered publication rates for the years 2002–2011, author interconnections, the rate at which new authors are added, and the domains that inform the work of author contributors. We also provided a content analysis of clinical and ethical themes within the relevant literature. We found a 27% growth in the number of papers over the period of study, professional diversity among a wide range of peripheral author contributors but only few authors who dominate the field, and few new technical paradigms and clinical themes that would fundamentally expand the landscape. The results inform both the science of consciousness as well as parallel ethics and policy studies of the potential for translational challenges of neuroimaging in research and health care of people with disordered states of consciousness.

  7. Taking Stock of Parent Education in the Family Courts: Envisioning a Public Health Model

    Science.gov (United States)

    Salem, Peter; Sandler, Irwin; Wolchik, Sharlene

    2012-01-01

    The paper reviewed the development and current status of the parent education movement in the Family Courts. Parent education programs are now being implemented in courts throughout the United States and have a high level of public acceptance; however, a stronger research methodology to evaluate the effects and continued work to align the goals with the content and teaching strategies of these programs are needed. A new conceptual framework is proposed for parent education, which views divorce as a public health problem for children as well as a legal issue. The three-level framework uses concepts from public health to align the goals, content and format of parent education programs and to enable rigorous evaluations of the outcomes achieved by these programs. PMID:23641191

  8. Problems with Permatrace: a note on digital image publication

    Directory of Open Access Journals (Sweden)

    Guy Hopkinson

    2004-01-01

    Full Text Available The methodology presented here developed out of work required to convert the hard-copy illustrations submitted to Internet Archaeology for publication of the 1975 excavations at Cricklade. The publication (and digital image preparatory work was funded by English Heritage and was, in part, an experiment designed to explore some of the possibilities presented by digital image publication. Various challenges in how to transform the drawings on permatrace to a digital format were encountered. While a full exploration of the potential of all areas of digital image preparation and publication was not possible, some interesting technical options were evaluated. This short article explains the processes applied in creating the images that were finally incorporated within the publication. It also examines some other avenues regarding the presentation of archaeological drawings that could be explored in both future Internet Archaeology content and other digital publications.

  9. "Less Than A Wife": A Study of Polycystic Ovary Syndrome Content in Teen and Women's Digital Magazines.

    Science.gov (United States)

    Sanchez, Ninive; Jones, Hillary

    2016-06-02

    Polycystic ovary syndrome (PCOS) is a major public health problem that affects women's physical and mental health. According to the US National Institutes of Health Office of Disease Prevention, there is a need to improve public awareness of the syndrome among health care providers and the public. Women's magazines are a type of "edutainment" that publish health content in addition to beauty, fashion, and entertainment content. These media have the potential to expose primarily female readers to content on PCOS and influence readers' beliefs and attitudes about women with PCOS. The objective of this study was to explore how digital (online) teen and women's magazines portray women with PCOS. We used data from the Alliance for Audited Media to identify popular digital teen and women's magazines with circulation rates ≥1,000,001. We also included magazines with circulation rates 100,001-1,000,000 directed toward racial and ethnic minority readers. A search of magazine websites over a 1-month period in 2015 yielded 21 magazines (eg, Glamour, Cosmopolitan en Español, Essence, and O, The Oprah Magazine) and 170 articles containing "PCOS" and "polycystic ovary syndrome." Textual analysis using a grounded theory approach was used to identify themes. Articles depicted PCOS symptoms as a hindrance to women's social roles as wives and mothers and largely placed personal responsibility on women to improve their health. To a lesser extent, women were depicted as using their personal experience with PCOS to advocate for women's health. Experiences of Latina and African American women and adolescents with PCOS were absent from women's magazine articles. The findings can inform health education programs that teach women to be critical consumers of PCOS-related content in digital women's magazines. Future research on PCOS content in digital teen and women's magazines can help researchers, patients, and consumer groups engage with the media to increase public awareness of PCOS.

  10. Accreditation in a public hospital: perceptions of a multidisciplinary team.

    Science.gov (United States)

    Camillo, Nadia Raquel Suzini; Oliveira, João Lucas Campos de; Bellucci Junior, José Aparecido; Cervilheri, Andressa Hirata; Haddad, Maria do Carmo Fernandez Lourenço; Matsuda, Laura Misue

    2016-06-01

    to analyze the perceptions of the multidisciplinary team on Accreditation in a public hospital. descriptive, exploratory, qualitative research, performed in May 2014, using recorded individual interviews. In total, 28 employees of a public hospital, Accredited with Excellence, answered the guiding question: "Tell me about the Accreditation system used in this hospital". The interviews were transcribed and subjected to content analysis. of the speeches, three categories emerged: Advantages offered by the Accreditation; Accredited public hospital resembling a private hospital; Pride/satisfaction for acting in an accredited public hospital. participants perceived Accreditation as a favorable system for a quality management in the public service because it promotes the development of professional skills and improves cost management, organizational structure, management of assistance and perception of job pride/satisfaction.

  11. Articles Published and Downloaded by Public Health Scientists: Analysis of Data From the CDC Public Health Library, 2011-2013.

    Science.gov (United States)

    Iskander, John; Bang, Gail; Stupp, Emma; Connick, Kathy; Gomez, Onnalee; Gidudu, Jane

    2016-01-01

    To describe scientific information usage and publication patterns of the Centers for Disease Control and Prevention (CDC) Public Health Library and Information Center patrons. Administratively collected patron usage data and aggregate data on CDC-authored publications from the CDC Library for 3 consecutive years were analyzed. The CDC Public Health Library and Information Center, which serves CDC employees nationally and internationally. Internal patrons and external users of the CDC Library. Three-year trends in full-text article publication and downloads including most common journals used for each purpose, systematic literature searches requested and completed, and subscriptions to a weekly public health current literature awareness service. From 2011 to 2013, CDC scientists published a total of 7718 articles in the peer-reviewed literature. During the same period, article downloads from the CDC Library increased 25% to more than 1.1 million, completed requests for reviews of the scientific literature increased by 34%, and electronic subscriptions to literature compilation services increased by 23%. CDC's scientific output and information use via the CDC Library are both increasing. Researchers and field staff are making greater use of literature review services and other customized information content delivery. Virtual public health library access is an increasingly important resource for the scientific practice of public health.

  12. Patriotic Rhetoric in Chinese Public Spaces

    Directory of Open Access Journals (Sweden)

    Pawel Zygadlo

    2017-10-01

    Full Text Available This paper begins with the analysis of the socio-cultural phenomenon known as “public space.” This analysis is followed by the reflection on distinctive features of public space in contemporary China. Subsequently, I focus on the use of public space by Chinese authorities for spreading official political and ideological discourse. For this purpose, I analyse the form and content of messages displayed in places of public utility. I conclude by showing what, how and why these are being displayed and widely promoted by the authorities. I argue that public space in China, on the one hand, is “public” in the sense that it is accessible and used by citizens; on the other, it is “arrested by authorities” and used for their socio-political and ideological purposes. Such an arrangement is a statement of the unvocalised agreement between the authorities and citizens that allows the former to avoid major conflicts with the latter and legitimise political power. In return, the latter enjoy a wide range of socio-cultural freedom and are being provided with psychological comfort resulting from identification with a greater endeavour of restoring the glory of the Chinese nation.

  13. The role of content marketing in social media content communities

    Directory of Open Access Journals (Sweden)

    Charmaine du Plessis

    2017-10-01

    Full Text Available Background: Content marketing has become a leading marketing technique in digital marketing communication and uses the point of view of consumers to build relationships by creating and sharing engaging content in social media that enhance their daily lives. Existing research on social media communities has focused mainly on social media marketing and virtual brand community perspectives while content marketing’s valuable and unobtrusive role in social media content communities has largely been overlooked. Objective: The purpose of this article was to investigate content marketing’s role in social media content communities to engage with the target audience in an innate manner. Method: This study made use of a directed, inductive content analysis of 51 practitioner documents relating to business-to-consumer content marketing practices to add another perspective to existing research on communities in social media. The content analysis was facilitated by using QDA Miner, a widely adopted and reliable qualitative data analysis software programme. Results: Three categories emerged from the data namely building content communities, platform-specific content and understanding channels. These categories provide sufficient evidence of how brands make use of social media content communities to connect with the target audience in an unobtrusive manner, in addition to being present in virtual brand communities. Conclusion: The findings make several contributions to the existing literature. Firstly, it provides a clearer distinction between brand and social media content communities. Secondly, it extends conceptions about social media communities to include content communities and, thirdly, it provides sufficient evidence of how content marketing could benefit a brand by naturally becoming part of social media conversations.

  14. Content validity and nursing sensitivity of community-level outcomes from the Nursing Outcomes Classification (NOC).

    Science.gov (United States)

    Head, Barbara J; Aquilino, Mary Lober; Johnson, Marion; Reed, David; Maas, Meridean; Moorhead, Sue

    2004-01-01

    To evaluate the content validity and nursing sensitivity of six community-level outcomes from the Nursing Outcomes Classification (NOC; Johnson, Maas, & Moorhead, 2000). A survey research design was used. Questionnaires were mailed to 300 public health nursing experts; 102 nurses responded. Experts evaluated between 11 and 30 indicators for each of the six outcomes for: (a) importance of the indicators for measuring the outcome, and (b) influence of nursing on the indicators. Content validity and nursing sensitivity of the outcomes were estimated with a modified Fehring technique. All outcomes were deemed important; only Community Competence had an outcome content validity score < .80. The outcome sensitivity score for Community Health: Immunity was .80; other outcome scores ranged from .62-.70. Indicator ratios for all 102 indicators met the study criterion for importance, with 87% designated as critical and 13% as supplemental. Sensitivity ratios reflected judgments that 45% of the indicators were sensitive to nursing intervention. The study provided evidence of outcome content validity and nursing sensitivity of the study outcomes; further validation research is recommended, followed by testing of the study outcomes in clinical practice. Community-level nursing-sensitive outcomes will potentially enable study of the efficacy and effectiveness of public health interventions focused on improving health of populations and communities.

  15. The Nature of Conflict in Firm-Client Relations: A Content Analysis of "Public Relations Journal," 1980-89.

    Science.gov (United States)

    Bourland, Pamela G.

    1993-01-01

    Finds that key issues recurring in articles regarding public relations firm-client relations were concerns over knowing each other's businesses, contributing to a consistent communication flow, finances, and "chemistry." Finds that conflict issues for public relations firms parallel those for advertising firms as reported in the advertising agency…

  16. Are the Public Health Responsibility Deal alcohol pledges likely to improve public health? An evidence synthesis.

    Science.gov (United States)

    Knai, Cécile; Petticrew, Mark; Durand, Mary Alison; Eastmure, Elizabeth; Mays, Nicholas

    2015-08-01

    The English Public Health Responsibility Deal (RD) is a public-private partnership involving voluntary pledges between industry, government and other actors in various areas including alcohol, and designed to improve public health. This paper reviews systematically the evidence underpinning four RD alcohol pledges. We conducted a systematic review of reviews of the evidence underpinning interventions proposed in four RD alcohol pledges, namely alcohol labelling, tackling underage alcohol sales, advertising and marketing alcohol, and alcohol unit reduction. In addition, we included relevant studies of interventions where these had not been covered by a recent review. We synthesized the evidence from 14 reviews published between 2002 and 2013. Overall, alcohol labelling is likely to be of limited effect on consumption: alcohol unit content labels can help consumers assess the alcohol content of drinks; however, labels promoting drinking guidelines and pregnancy warning labels are unlikely to influence drinking behaviour. Responsible drinking messages are found to be ambiguous, and industry-funded alcohol prevention campaigns can promote drinking instead of dissuading consumption. Removing advertising near schools can contribute to reducing underage drinking; however, community mobilization and law enforcement are most effective. Finally, reducing alcohol consumption is more likely to occur if there are incentives such as making lower-strength alcohol products cheaper. The most effective evidence-based strategies to reduce alcohol-related harm are not reflected consistently in the RD alcohol pledges. The evidence is clear that an alcohol control strategy should support effective interventions to make alcohol less available and more expensive. © 2015 Society for the Study of Addiction.

  17. Effect of the Fukushima nuclear disaster on global public acceptance of nuclear energy

    International Nuclear Information System (INIS)

    Kim, Younghwan; Kim, Minki; Kim, Wonjoon

    2013-01-01

    The Fukushima nuclear disaster has significantly changed public attitudes toward nuclear energy. It is important to understand how this change has occurred in different countries before the global community revises existing nuclear policies. This study examines the effect of the Fukushima disaster on public acceptance of nuclear energy in 42 countries. We find that the operational experience of nuclear power generation which has significantly affected positive public opinion about nuclear energy became considerably negative after the disaster, suggesting fundamental changes in public acceptance regardless of the level of acceptance before the disaster. In addition, contrary to our expectation, the proportion of nuclear power generation is positively and significantly related to public acceptance of nuclear energy after the Fukushima accident and government pressure on media content led to a greater decrease in the level of public acceptance after the accident. Nuclear energy policymakers should consider the varied factors affecting public acceptance of nuclear energy in each country depending on its historical, environmental, and geographical circumstances before they revise nuclear policy in response to the Fukushima accident. - Highlights: • Fukushima accident has negatively changed public attitudes toward nuclear energy. • Effect of operational experience became considerably negative after the accident. • Effect of proportion of nuclear power generation is positive after the accident. • Effect of government pressure on media content became negative after the accident. • Country specific policy responses on nuclear public acceptance are required

  18. Leadership Strategies of Performance Measures Impacts in Public Sector Management: A National Content Analysis.

    Science.gov (United States)

    Kubala, James Joseph

    A quantitative and qualitative study examined three leadership strategies found in performance-based management (human resource, scientific management and political strategies used in public sector management); a framework by which performance measurement (PM) supports leadership strategies; and how the strategies impact PM. It examined leadership…

  19. Western public awareness of the Ukrainian famine in the early 1930s

    OpenAIRE

    Edvīns Šnore

    2013-01-01

    Doctoral thesis: Western public awareness of the Ukrainian famine in the early 1930s Doctoral thesis “Western public awareness of the Ukrainian famine in the early 1930s” analyses the reaction of the West to the Ukrainian famine in 1932/33. The thesis chronologically reviews 1932/33 Western press publications about the Ukrainian famine, analyses their content and factors, which influenced it such as the work of Western correspondents in Moscow, their motivations, Soviet censors...

  20. Siberian Regional Identity in the Context of Historical Consciousness (Content Analysis of Tomsk Regional Media

    Directory of Open Access Journals (Sweden)

    A V Bocharov

    2011-12-01

    Full Text Available The article presents a model to study the Siberian regional identity in the context of historical consciousness, as well as the results of its practical application in the content analysis of the publications by the Tomsk regional media. On the basis of the content analysis procedures the author demonstrates how, through historical memory, the regional identity is formed and manifested in the regional media in various spheres of society.

  1. The Role of Content Aggregators In GEOValue

    Science.gov (United States)

    Wright, D. J.; Breyer, S.; Hogeweg, M.; Foust, J.; Jordan, L.; Plunkett, G.

    2016-12-01

    Data (aka content) in the form of numbers or layers, and transformed into information by way of maps, images, graphs, charts, tables, even stories, are foundational for a myriad of decision-makers. Recent advances in information technology, as well as civil remote sensing of the Earth, are rapidly allowing us to advance beyond mere static data collection and archiving, further enabling information awareness and understanding, and leading us towards knowledge and better decision making. However, such volumes, velocities, and varieties of data streams also bring with them serious dilemmas with regard to effective organization, cataloging, and easy access. This is where the role of aggregator comes in, with their provision of the necessary sustainability and reliability of information via proven, well-engineered platforms, all with the necessary interoperability and openness as guaranteed through the adoption of established standards. Information technology (IT) giants such as Google, Facebook, IBM and Apple are well known for aggregating just about every aspect of life in modern society, from our music to our mood swings. A use case of the Environmental Systems Research Institute (aka Esri) is presented as a geospatial aggregator. It has over the years, compiled, assembled and produced a carefully curated library of public content into a global "Living Atlas of the World," organized into different themes such as Earth observation, transportation, demographics, natural hazards, ecological land units, elevation, and more. Among a myriad of decision scenarios with this content to be presented is the tracking of sea ice in the Arctic, estimating potential impact to shipping lanes or coastal infrastructure, and forecasting future conditions. Esri as the main aggregator of Living Atlas content continues to welcome not only contributors who will publish new content to be included in this global Atlas, but fellow curators who will assist in reviewing, organizing, and even

  2. Health and Safety Considerations of Fermented Sausages

    Directory of Open Access Journals (Sweden)

    Askild Holck

    2017-01-01

    Full Text Available Fermented sausages are highly treasured traditional foods. A large number of distinct sausages with different properties are produced using widely different recipes and manufacturing processes. Over the last years, eating fermented sausages has been associated with potential health hazards due to their high contents of saturated fats, high NaCl content, presence of nitrite and its degradation products such as nitrosamines, and use of smoking which can lead to formation of toxic compounds such as polycyclic aromatic hydrocarbons. Here we review the recent literature regarding possible health effects of the ingredients used in fermented sausages. We also go through attempts to improve the sausages by lowering the content of saturated fats by replacing them with unsaturated fats, reducing the NaCl concentration by partly replacing it with KCl, and the use of selected starter cultures with desirable properties. In addition, we review the food pathogenic microorganisms relevant for fermented sausages (Escherichia coli, Salmonella enterica, Staphylococcus aureus, Listeria monocytogenes, Clostridium botulinum, and Toxoplasma gondii and processing and postprocessing strategies to inhibit their growth and reduce their presence in the products.

  3. Police Tweets and Public Perceptions of Safety and Police Performance: An Experiment on Framing and Other Tweet Content

    Directory of Open Access Journals (Sweden)

    Imke Smulders

    2017-05-01

    Full Text Available The introduction of new media as a means of communication by the police triggers interesting questions about the impact of such new developments, such as the effect on people’s safety perceptions. Since communication is mostly overlooked as a possible determinant of safety perception, this led to a research project into the relationship between Twitter use by community policing officers and citizen’s perceptions of safety. This article reports on a part of this study, an experiment on framing and other linguistic effects of tweets by police officers. To assess the aforementioned relationship, it is important to examine how the precise content of a community policing officer’s tweet is perceived by the public. In an experimental setting the effects of gain versus loss frames, implicit versus explicit advice and style of addressing have been tested, with regard to safety perceptions and several related factors. The results show that gain framed tweets yield significantly more positive responses concerning opinion about police performance, perceived risk of burglary or assault, safety perception and marginally for perceived crime level in the neighbourhood. Including an explicitly or implicitly formulated piece of advice in the tweets doesn’t make a difference in any of the queried variables and style of addressing has only small effects: formal address leads to slightly more positive opinions about police performance than impersonal address.  The results show that formulation aspects – specifically framing – are worth taking into account in safety communications and that this type of research is beneficial for studying effects of social media.

  4. Marketing messages in food and alcohol magazine advertisements, variations across type and nutritional content of promoted products: a content analysis.

    Science.gov (United States)

    Pitts, A; Burke, W; Adams, J

    2014-09-01

    'Marketing messages' are the themes used in advertisements to promote products. We explored the frequency of different marketing messages used in food and alcohol advertisements in UK women's magazines and associations with the type and nutritional content of products promoted. All advertisements for food and alcohol in 108 issues of popular UK monthly women's magazines were identified and text-based marketing messages classified using a bespoke coding framework. This information was linked to existing data on the type (i.e. food group) and nutritional content of advertised products. A total of 2 687 marketing messages were identified in 726 advertisements. Consumer messages such as 'taste' and 'quality' were most frequently found. Marketing messages used in advertisements for food and alcohol were notably different. The relationship between type and nutritional content of products advertised and marketing messages used was not intuitive from a consumer perspective: advertisements for foods 'high in fat and/or sugar' were less likely to use messages related to health, but more likely to use messages emphasizing reduced amounts of specific nutrients. Almost all advertisements included consumer-related marketing messages. Marketing messages used were not always congruent with the type or nutritional content of advertised products. These findings should be considered when developing policy. © The Author 2013. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. [CONTENT OF TRANS FATTY ACIDS IN FOOD PRODUCTS IN SPAIN].

    Science.gov (United States)

    Robledo de Dios, Teresa; Dal Re Saavedra, M Ángeles; Villar Villalba, Carmen; Pérez-Farinós, Napoleón

    2015-09-01

    trans fatty acids are associated to several health disorders, as ischemic heart disease or diabetes mellitus. to assess the content of trans fatty acids in products in Spain, and the percentage of trans fatty acids respecting total fatty acids. 443 food products were acquired in Spain, and they were classified into groups. The content in fatty acids was analyzed using gas chromatography. Estimates of central tendency and variability of the content of trans fatty acids in each food group were computed (in g of trans fatty acids/100 g of product). The percentage of trans fatty acids respecting total fatty acids was calculated in each group. 443 products were grouped into 42 groups. Median of trans fatty acids was less than 0.55 g / 100 g of product in all groups except one. 83 % of groups had less than 2 % of trans fatty acids, and 71 % of groups had less than 1 %. the content of trans fatty acids in Spain is low, and it currently doesn't play a public health problem. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  6. Analysis of the literature pertaining to the education of public health professionals

    Directory of Open Access Journals (Sweden)

    Connie J Evashwick

    2013-11-01

    Full Text Available A well-educated workforce is essential to the infrastructure of a public health system. At the time when global focus on public health is increasing, a severe shortage of public health professionals is projected. A strong educational framework is imperative to ensure the capacity and capability of the worldwide public health workforce for the future. Frenk and Chen (2011 comment that academic public health has done far less than medicine or nursing to examine its pedagogy. The goal of this study is to examine the literature pertaining to the education of public health professionals in order to document the extent to which those preparing public health professionals think about what they teach, how they teach, and what the results of the instruction are. The specific objectives are to (1 identify relevant peer reviewed literature, (2 analyze that literature for content, (3 characterize the literature according to type of methodology, and (4 draw conclusions and implications to enhance future pedagogical efforts. The study searched three bibliographic sources for articles written in English between 2000-2012. The search of PubMed, Scopus, Education Full Text identified 576 unique articles. The articles were analyzed according to ten content themes and four format categories. The conclusions are that those teaching public health professionals devote considerable thought to what and how they teach, although original research and evaluation studies are fewer than descriptive reports of courses, programs and curricula. A journal devoted specifically to articles pertaining to education of public health professionals will encourage academicians to write articles sharing approaches to educating the public health workforce.

  7. Analysing public relations education through international standards: The Portuguese case

    OpenAIRE

    Gonçalves, Gisela Marques Pereira; Spínola, Susana de Carvalho; Padamo, Celma

    2013-01-01

    By using international reports on PR education as a benchmark we analyse the status of PR higher education in Portugal. Despite differences among the study programs, the findings reveal that the standard five courses recommendation by the Commission on Public Relations Education (CPRE) are a part of Portuguese undergraduate curriculum. This includes 12 of the 14 content field guidelines needed to achieve the ideal master's program. Data shows, however, the difficulty of positioning public rel...

  8. New public management reforms in Nigerian democratic governance

    African Journals Online (AJOL)

    This paper brings concepts and ideas from around the world about the need for and ways of achieving more responsive and accountable new public management within the framework of democratic governance. The paper adopts a content analysis method through the use of secondary data. The findings of the paper ...

  9. A partnership development process assessment scale for public health nurses in Japan.

    Science.gov (United States)

    Shigematsu, Yukako; Hatano, Yoko; Kimura, Hitoe

    2015-01-01

    The objective of this study was to develop and test a Partnership Development Process Assessment (PDPA) scale for content and construct validity and internal consistency reliability. This is needed to document and evaluate community health partnership development processes between public health nurses and community-based organizations in Japan. The study was conducted in three phases. Ten semi-structured interviews were conducted to generate items for a new scale. Thirty items were generated and reviewed by an expert panel for content validity and item refinement. A national postal survey of public health nurses was conducted to determine the scale's internal structure, evaluate its reliability, and explore its construct and criterion validity. Validity and reliability testing of the PDPA scale using a content validity index and analysis of correlations with an existing scale were performed. Twenty-six items were selected and grouped into four factors: activities to share roles to manage community health issues, platform activities to support partnerships, activities to evaluate partnership practices, and activities to share information regarding community health issues. After factor analysis, 23 items were retained. The PDPA scale is a valid and reliable instrument for public health nurses to assess partnership development activities. © 2015 Wiley Periodicals, Inc.

  10. Public information and licensing procedures for nuclear installations. European experience

    International Nuclear Information System (INIS)

    Mayoux, J.C.; Chevillard, F.; Mutschler, U.; Stubbe, C.

    1981-10-01

    This paper reviews the licensing procedures for nuclear installations in various European countries and examines the form, content and methods selected for information and consultation of the public. The author stresses the importance of this stage in the procedure, both for the nuclear operator and the public authorities, given the population's concern about the environment. He concludes that, irrespective of its complexity, the nuclear field cannot remain the concern of a few initiates competent to take decisions and that, consequently, this implies creation of new information systems to meet the public's desire to participate more directly in the process. (NEA) [fr

  11. Cosmetic tourism: public opinion and analysis of information and content available on the Internet.

    Science.gov (United States)

    Nassab, Reza; Hamnett, Nathan; Nelson, Kate; Kaur, Simranjit; Greensill, Beverley; Dhital, Sanjiv; Juma, Ali

    2010-01-01

    The medical tourism market is a rapidly growing sector fueled by increasing health care costs, longer domestic waiting times, economic recession, and cheaper air travel. The authors investigate public opinion on undergoing cosmetic surgery abroad and then explore the information patients are likely to encounter on the Internet when searching for such services. A poll of 197 members of the general public was conducted in the United Kingdom. An Internet search including the terms plastic surgery abroad was conducted, and the first 100 relevant sites were reviewed. Of the 197 respondents, 47% had considered having some form of cosmetic surgery. Most (97%) would consider going abroad for their procedure. The Internet was a source of information for 70%. The review of the first 100 sites under "plastic surgery abroad" revealed that most centers were located in Eastern Europe (26%), South America (14%), and the Far East (11%). Exploring the information provided on the Web sites, we found 37% contained no information regarding procedures. Only 10% of sites contained any information about potential complications. Even less frequently mentioned (4%) were details of aftercare or follow-up procedures. The authors found that the overwhelming majority of respondents considering plastic surgery would also consider seeking cosmetic surgical treatment abroad. The Internet sites that appear most prominently in an online search contained a distinct lack of information for potential patients, particularly with regard to complications and aftercare. There is, therefore, a need for improved public awareness and education about the considerations inherent in medical tourism. The introduction of more stringent regulations for international centers providing such services should also be considered to help safeguard patients.

  12. Adolescents' self-presentation on a teen dating web site: a risk-content analysis.

    Science.gov (United States)

    Pujazon-Zazik, Melissa A; Manasse, Stephanie M; Orrell-Valente, Joan K

    2012-05-01

    To analzye adolescents' profiles on MyLol.net, a teen dating Web site, for risk content. We hypothesized that risk content would vary by age and gender. We selected and coded 752 publicly viewable profiles of adolescents aged 14-18 years for the following five risks: sex, alcohol, drugs, cigarettes, and violence. Of the total profiles, 27.7% contained risk-related content: 15.8% sexual behavior, 13.8% alcohol use, 1.6% drug use, 6.8% cigarette smoking, and .9% violence activity. Being female, "single" relationship status, and use of profanity (p cyberbullies and sexual predators). Stronger universal Internet policies and education are needed to help protect adolescents. Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  13. The Empirical content of theories in judgment and decision making: Shortcomings and remedies

    Directory of Open Access Journals (Sweden)

    Andreas Glockner

    2011-12-01

    Full Text Available According to Karl Popper, we can tell good theories from poor ones by assessing their empirical content (empirischer Gehalt, which basically reflects how much information they convey concerning the world. ``The empirical content of a statement increases with its degree of falsifiability: the more a statement forbids, the more it says about the world of experience.'' Two criteria to evaluate the empirical content of a theory are their level of universality (Allgemeinheit and their degree of precision (Bestimmtheit. The former specifies how many situations it can be applied to. The latter refers to the specificity in prediction, that is, how many subclasses of realizations it allows. We conduct an analysis of the empirical content of theories in Judgment and Decision Making (JDM and identify the challenges in theory formulation for different classes of models. Elaborating on classic Popperian ideas, we suggest some guidelines for publication of theoretical work.

  14. Nuclear power. Nuclear fuel cycle and waste management. 1990-2002. International Atomic Energy Agency publications

    International Nuclear Information System (INIS)

    2002-02-01

    This document lists all sales publications of the International Atomic Energy Agency dealing with Nuclear Power, Nuclear Fuel Cycle and Waste Management, issued during the period 1990-2002. It gives a short abstract of these publications along with contents and their costs

  15. Manual of References, Creating Tables and Figures in Scholarly Publications: APA 6 Rules

    OpenAIRE

    Mehmet Ali Akkaya

    2016-01-01

    One precondition of contribution of a discipline to its field, to the scientific word in general and to the entire humankind is producing qualified scientific publications in the related field or discipline. National and international standard(s) provided for citing and referencing tables and figures, in addition to the content (and context) of the scientific publications might provide the relevant publication to be more widely and correctly read and reviewed. This study deals with adaptation...

  16. Pandemics in the age of Twitter: content analysis of Tweets during the 2009 H1N1 outbreak.

    Directory of Open Access Journals (Sweden)

    Cynthia Chew

    Full Text Available BACKGROUND: Surveys are popular methods to measure public perceptions in emergencies but can be costly and time consuming. We suggest and evaluate a complementary "infoveillance" approach using Twitter during the 2009 H1N1 pandemic. Our study aimed to: 1 monitor the use of the terms "H1N1" versus "swine flu" over time; 2 conduct a content analysis of "tweets"; and 3 validate Twitter as a real-time content, sentiment, and public attention trend-tracking tool. METHODOLOGY/PRINCIPAL FINDINGS: Between May 1 and December 31, 2009, we archived over 2 million Twitter posts containing keywords "swine flu," "swineflu," and/or "H1N1." using Infovigil, an infoveillance system. Tweets using "H1N1" increased from 8.8% to 40.5% (R(2 = .788; p<.001, indicating a gradual adoption of World Health Organization-recommended terminology. 5,395 tweets were randomly selected from 9 days, 4 weeks apart and coded using a tri-axial coding scheme. To track tweet content and to test the feasibility of automated coding, we created database queries for keywords and correlated these results with manual coding. Content analysis indicated resource-related posts were most commonly shared (52.6%. 4.5% of cases were identified as misinformation. News websites were the most popular sources (23.2%, while government and health agencies were linked only 1.5% of the time. 7/10 automated queries correlated with manual coding. Several Twitter activity peaks coincided with major news stories. Our results correlated well with H1N1 incidence data. CONCLUSIONS: This study illustrates the potential of using social media to conduct "infodemiology" studies for public health. 2009 H1N1-related tweets were primarily used to disseminate information from credible sources, but were also a source of opinions and experiences. Tweets can be used for real-time content analysis and knowledge translation research, allowing health authorities to respond to public concerns.

  17. Motivational and Parental Mediation Factors Related to Kenyan Adolescents' Intake of Sexual Radio and TV Content.

    Science.gov (United States)

    Ngula, Kyalo Wa; Miller, Ann Neville; Mberia, Hellen K

    2018-06-01

    Research on the influence of media on youths' sexual behavior in sub-Saharan Africa has focused almost entirely on the effects of multimedia health communication campaigns and edutainment programming. Scholarly literature is nearly silent about the influence of the multiple hours that young people in many sub-Saharan nations spend immersed in increasingly sex-heavy entertainment programming. We surveyed a stratified cluster sample of 437 Nairobi public high school students about motivational and parental mediation factors associated with their exposure to sexual radio and TV content. Watching sexual content in the bedroom predicted higher intake of both sexual radio and TV content. Believing that parents were successful in their efforts to limit media use predicted lower intake of both sexual radio and TV content. A friend/companion motive for watching was associated with taking in higher levels of sexual TV content. For day school students, watching sexual content in the sitting room also predicted higher levels of exposure to sexual TV content.

  18. FINANCIAL REPORTING IN PUBLIC INSTITUTIONS AND NON-FINANCIAL ENTITIES. SIMILARITIES AND DIFFERENCES

    OpenAIRE

    Daniela Vitan

    2011-01-01

    The present paperwork contains issues regarding financial reporting at the public institutions and non – financial entities. The main aspects are regarding the obligation of all entities to present the financial statements, the content of financial statements in public institutions and non-financial entities. Also, is presented the similarities and the differences aspects between financial reporting of these two patrimonial entities.

  19. Content Instruction through a Foreign Language. A Report on the 1992-1993 TCE Programme. Research and Fieldwork No. 18.

    Science.gov (United States)

    Rasanen, Anne, Ed.; Marsh, David, Ed.

    This volume of articles is a report from the national teacher in-service development program in teaching content through a foreign language at the Continuing Education Centre of the University of Jyvaskyla, Finland. This publication is mainly in English, because of the basic rationale of the Teaching Content through English (TCE) programme, and…

  20. What Do Publication Advisers Think Schools Are For?

    Science.gov (United States)

    Campbell, Laurence R.

    1979-01-01

    Reports results of a survey of high school publication advisers' views on what high schools should teach, types of criticism they receive for news media content, and job-related duties they perform. Notes that many school newspapers avoid covering controversial issues, and stresses the need for freedom of speech for student journalists. (GW)

  1. 17 CFR 210.3A-05 - Special requirements as to public utility holding companies.

    Science.gov (United States)

    2010-04-01

    ... Consolidated and Combined Financial Statements § 210.3A-05 Special requirements as to public utility holding companies. There shall be shown in the consolidated balance sheet of a public utility holding company the... SECURITIES AND EXCHANGE COMMISSION FORM AND CONTENT OF AND REQUIREMENTS FOR FINANCIAL STATEMENTS, SECURITIES...

  2. A Bluetooth Solution for Public Information Systems

    Directory of Open Access Journals (Sweden)

    Nicolae Radu MARSANU

    2011-01-01

    Full Text Available This paper gives insights into the opportunities offered by the Bluetooth technology. Bluetooth advertising proves to be a cheap and strong tool for enriching and improving the experience offered by a public transport system, by delivering dense and essential information about topics of interest. Alongside the Java platform, new applications can be designed and implemented to make use of the already available Bluetooth technology incorporated in devices in the target public’s custody. The paper sets focus on the segment of ready to be made available content regarding general information about the routes and timetables of the vehicles integrated in a public transport system.

  3. Content Maps: A Teaching and Assessment Tool for Content Knowledge

    Science.gov (United States)

    Ward, Phillip; Lehwald, Harry; Lee, Yun Soo

    2015-01-01

    Developing content knowledge in teachers presents a constant challenge for teacher educators. This article introduces a teaching and assessment tool called a "content map," which allows teacher educators, teachers, and coaches to conceptualize the scope, sequence, and relational characteristics of the content being taught. Content maps…

  4. How should health service organizations respond to diversity? A content analysis of six approaches

    NARCIS (Netherlands)

    Seeleman, C.; Essink-Bot, M.-L.; Stronks, K.; Ingleby, D.

    2015-01-01

    Background Health care organizations need to be responsive to the needs of increasingly diverse patient populations. We compared the contents of six publicly available approaches to organizational responsiveness to diversity. The central questions addressed in this paper are: what are the most

  5. Toastmaster's Inspired Pedagogical Changes: From a Speech Class into a Public Relations Course

    Science.gov (United States)

    Shadinger, David

    2016-01-01

    Action research is used to view pedagogical changes, first in a speech class and then in a public relations course over a five-year period. The course instructor gained experience as a member of a Toastmasters International club and used Toastmasters-like activities, to revise content in the courses. Ultimately, students in the public relations…

  6. An intelligent content discovery technique for health portal content management.

    Science.gov (United States)

    De Silva, Daswin; Burstein, Frada

    2014-04-23

    Continuous content management of health information portals is a feature vital for its sustainability and widespread acceptance. Knowledge and experience of a domain expert is essential for content management in the health domain. The rate of generation of online health resources is exponential and thereby manual examination for relevance to a specific topic and audience is a formidable challenge for domain experts. Intelligent content discovery for effective content management is a less researched topic. An existing expert-endorsed content repository can provide the necessary leverage to automatically identify relevant resources and evaluate qualitative metrics. This paper reports on the design research towards an intelligent technique for automated content discovery and ranking for health information portals. The proposed technique aims to improve efficiency of the current mostly manual process of portal content management by utilising an existing expert-endorsed content repository as a supporting base and a benchmark to evaluate the suitability of new content A model for content management was established based on a field study of potential users. The proposed technique is integral to this content management model and executes in several phases (ie, query construction, content search, text analytics and fuzzy multi-criteria ranking). The construction of multi-dimensional search queries with input from Wordnet, the use of multi-word and single-word terms as representative semantics for text analytics and the use of fuzzy multi-criteria ranking for subjective evaluation of quality metrics are original contributions reported in this paper. The feasibility of the proposed technique was examined with experiments conducted on an actual health information portal, the BCKOnline portal. Both intermediary and final results generated by the technique are presented in the paper and these help to establish benefits of the technique and its contribution towards effective

  7. A Comparative Study on New Media Marketing in Domestic and Foreign Public Libraries

    Directory of Open Access Journals (Sweden)

    Xu Yan

    2017-01-01

    Full Text Available Currently, new media has become the popular platform for brand marketing and services promoting of public libraries. Using the method of online survey, literature analysis and comparative analysis, this paper chooses 4 foreign public libraries and 4 domestic public libraries as the research samples and compares the differences in new media marketing between them from new media marketing tools, marketing content and marketing strategies, then makes some proposals and measures to perfect domestic public libraries’ new media marketing, so as to provide references to improve the libraries’ social awareness and benefits.

  8. FORECAST, ORGANIZATION-COORDINATION AND MOTIVATION IN LOCAL PUBLIC ADMINISTRATION MANAGEMENT

    OpenAIRE

    Petronela SCUTARIU

    2015-01-01

    The proper functioning of local administrative system is not possible without the exercise of the functions of local public administration management. From such a direction, in this article we intend to analyze the contents of the functions of forecast, of organization-coordination and of motivation, in order to show how each of these contributes to good management of local public affairs. Defining the mission, the objectives of local government and the actions to be taken to achieve them, th...

  9. Building a biodiversity content management system for science, education, and outreach

    Directory of Open Access Journals (Sweden)

    C S Parr

    2006-01-01

    Full Text Available We describe the system architecture and data template design for the Animal Diversity Web (http://www.animaldiversity.org, an online natural history resource serving three audiences: 1 the scientific community, 2 educators and learners, and 3 the general public. Our architecture supports highly scalable, flexible resource building by combining relational and object-oriented databases. Content resources are managed separately from identifiers that relate and display them. Websites targeting different audiences from the same database handle large volumes of traffic. Content contribution and legacy data are robust to changes in data models. XML and OWL versions of our data template set the stage for making ADW data accessible to other systems.

  10. Trade Policy Preferences and the Factor Content of Trade

    DEFF Research Database (Denmark)

    Jäkel, Ina Charlotte; Smolka, Marcel

    demonstrate that the factor price changes induced by trade policy are negatively correlated with the factor content of free trade (and therefore factor abundance). Using large-scale international survey data, we test whether these predicted distributional effects are reflected in the trade policy preferences...... of workers with different labor market skills. In order to isolate the effects of factor abundance from other skill-related confounding factors, we employ a within-skill-group estimator that exploits the cross-country variation in the factor content of free trade. In line with theory, the data show......This paper provides a theoretical and empirical analysis of public opinion towards free trade, investigating cleavages both between and within countries. We study the distributional effects of trade policy in a neoclassical economy with not just two, but many input factors in production. We...

  11. Public Communication on Urban Air Pollution

    International Nuclear Information System (INIS)

    Otra, C.; Sala, R.

    2014-01-01

    The aim of this study was to analyze the state of public information in the field of air pollution in Spain. We conducted semi-structured interviews with members of public agencies, technical experts, scientists, and members of non governmental associations together with a documentary analysis of air pollution documents (plans, reports, etc.). We tried to characterize the information actions on air quality carried out in Spanish cities during the last years. In the results section we first analyze the ideas, concerns and considerations that underlie the actions of public information on air pollution, as well as the main challenges of public communication on this subject, according to the documents and the different experts consulted. We analyze the various contents of information transmitted nowadays (on levels of pollution, health impacts and mitigation or protection actions), as well as the mechanisms by which it is communicated, both continuously and in the case of threshold overcoming episodes. We also review the different media used to communicate air pollution information (Internet, mobile applications and other forms) and other issues such as information audiences, or the perceived impacts of information provided. Finally, the implications for more diverse and effective public involvement strategies in air pollution are discussed. (Author)

  12. Can existing mobile apps support healthier food purchasing behaviour? Content analysis of nutrition content, behaviour change theory and user quality integration.

    Science.gov (United States)

    Flaherty, Sarah-Jane; McCarthy, Mary; Collins, Alan; McAuliffe, Fionnuala

    2018-02-01

    To assess the quality of nutrition content and the integration of user quality components and behaviour change theory relevant to food purchasing behaviour in a sample of existing mobile apps. Descriptive comparative analysis of eleven mobile apps comprising an assessment of their alignment with existing evidence on nutrition, behaviour change and user quality, and their potential ability to support healthier food purchasing behaviour. Mobile apps freely available for public use in GoogePlay were assessed and scored according to agreed criteria to assess nutrition content quality and integration of behaviour change theory and user quality components. A sample of eleven mobile apps that met predefined inclusion criteria to ensure relevance and good quality. The quality of the nutrition content varied. Improvements to the accuracy and appropriateness of nutrition content are needed to ensure mobile apps support a healthy behaviour change process and are accessible to a wider population. There appears to be a narrow focus towards behaviour change with an overemphasis on behavioural outcomes and a small number of behaviour change techniques, which may limit effectiveness. A significant effort from the user was required to use the mobile apps appropriately which may negatively influence user acceptability and subsequent utilisation. Existing mobile apps may offer a potentially effective approach to supporting healthier food purchasing behaviour but improvements in mobile app design are required to maximise their potential effectiveness. Engagement of mobile app users and nutrition professionals is recommended to support effective design.

  13. CERN Public homepage takes its first step towards web 2.0

    CERN Multimedia

    2009-01-01

    Some of you may have noticed a change of format on the CERN public homepage recently. The Bulletin catches up with Dan Noyes, CERN web content manager, to find out what is happening. With over 7000 websites in the cern.ch domain, CERN’s web landscape is a challenging one to manage. Dan Noyes, who joined CERN a year ago, is the web content manager within the Communication group, which is mandated to develop the public and user websites as well as developing standards and guidelines for the wider CERN web. The recent changes made to the public homepage were the first small step towards some quite major changes proposed for CERN’s websites over the next couple of years. Currently, one of the problems of CERN’s websites is that the quantity and the diversity of the information in them make them difficult to manage, if one wants to avoid duplication and to keep information updated and easy to find. This is also aggravated by the lack of a standard design philosophy a...

  14. mLearning and Creative Practices: A Public Challenge?

    Science.gov (United States)

    Antonczak, Laurent; Keegan, Helen; Cochrane, Thomas

    2016-01-01

    The ethos of open sharing of experiences and user generated content enabled by Mobile social media can be problematic in some cases (politics, gender, minorities), and it is not fully understood within the creative and academic sector. Creative people, students, and lecturers can misconceive the value and issues around open and public access to…

  15. Public Relations in the State Institutions from Galati

    Directory of Open Access Journals (Sweden)

    Daniela Aurelia Tanase Popa

    2016-06-01

    Full Text Available The paper aims at identifying and analyzing specific public relations activities in various state institutions from Galati in order to shape a PR typological profile in this geographic area. From the methodological point of view, the paper is based on in-depth interview technique for data collection and content analysis as a method of interpretation. The purpose of this qualitative study is to investigate the professional activity of the specialist in public relations in state institutions in Galati and achieving it was made possible through a structured interview guide on three indicators: professional environment, typological profile, professional responsibility.

  16. Social Media Analysis For Organizations: Us Northeastern Public And State Libraries Case Study

    OpenAIRE

    Collins, Matthew; Karami, Amir

    2018-01-01

    Social networking sites such as Twitter have provided a great opportunity for organizations such as public libraries to disseminate information for public relations purposes. However, there is a need to analyze vast amounts of social media data. This study presents a computational approach to explore the content of tweets posted by nine public libraries in the northeastern United States of America. In December 2017, this study extracted more than 19,000 tweets from the Twitter accounts of sev...

  17. Developing Technological Pedagogical Content Knowledge in pre-service science teachers: Support from blended learning

    NARCIS (Netherlands)

    Alayyar, G.; Fisser, Petra; Voogt, Joke

    2012-01-01

    The Technological Pedagogical Content Knowledge (TPACK) framework has been used to prepare pre-service science teachers at the Public Authority of Applied Education and Training in Kuwait for ICT integration in education. Pre-service teachers worked in teams to design an ICT solution for an

  18. Developing Technological Pedagogical Content Knowledge in pre-service science teachers : Support from blended learning

    NARCIS (Netherlands)

    Alayyar, G.; Fisser, Petra; Voogt, Joke

    2012-01-01

    The Technological Pedagogical Content Knowledge (TPACK) framework has been used to prepare pre-service science teachers at the Public Authority of Applied Education and Training in Kuwait for ICT integration in education. Pre-service teachers worked in teams to design an ICT solution for an

  19. A cell-microelectronic sensing technique for profiling cytotoxicity of chemicals

    International Nuclear Information System (INIS)

    Boyd, Jessica M.; Huang, Li; Xie Li; Moe, Birget; Gabos, Stephan; Li Xingfang

    2008-01-01

    A cell-microelectronic sensing technique is developed for profiling chemical cytotoxicity and is used to study different cytotoxic effects of the same class chemicals using nitrosamines as examples. This technique uses three human cell lines (T24 bladder, HepG2 liver, and A549 lung carcinoma cells) and Chinese hamster ovary (CHO-K1) cells in parallel as the living components of the sensors of a real-time cell electronic sensing (RT-CES) method for dynamic monitoring of chemical toxicity. The RT-CES technique measures changes in the impedance of individual microelectronic wells that is correlated linearly with changes in cell numbers during t log phase of cell growth, thus allowing determination of cytotoxicity. Four nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosodiphenylamine (NDPhA), N-nitrosopiperidine (NPip), and N-nitrosopyrrolidine (NPyr), were examined and unique cytotoxicity profiles were detected for each nitrosamine. In vitro cytotoxicity values (IC 50 ) for NDPhA (ranging from 0.6 to 1.9 mM) were significantly lower than the IC 50 values for the well-known carcinogen NDMA (15-95 mM) in all four cell lines. T24 cells were the most sensitive to nitrosamine exposure among the four cell lines tested (T24 > CHO > A549 > HepG2), suggesting that T24 may serve as a new sensitive model for cytotoxicity screening. Cell staining results confirmed that administration of the IC 50 concentration from the RT-CES experiments inhibited cell growth by 50% compared to the controls, indicating that the RT-CES method provides reliable measures of IC 50 . Staining and cell-cycle analysis confirmed that NDPhA caused cell-cycle arrest at the G0/G1 phase, whereas NDMA did not disrupt the cell cycle but induced cell death, thus explaining the different cytotoxicity profiles detected by the RT-CES method. The parallel cytotoxicity profiling of nitrosamines on the four cell lines by the RT-CES method led to the discovery of the unique cytotoxicity of NDPhA causing cell

  20. A cell-microelectronic sensing technique for profiling cytotoxicity of chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Boyd, Jessica M [Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, 10-102 Clinical Sciences Building, Edmonton, Alberta, T6G 2G3 (Canada); Huang, Li [Environmental Health Sciences, Department of Public Health Sciences, School of Public Health, University of Alberta, 10-102 Clinical Sciences Building, Edmonton, Alberta, T6G 2G3 (Canada); Li, Xie; Moe, Birget [Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, 10-102 Clinical Sciences Building, Edmonton, Alberta, T6G 2G3 (Canada); Gabos, Stephan [Public Health Surveillance and Environmental Health, Alberta Health and Wellness, 10025 Jasper Avenue, Box 1360, Edmonton, Alberta, T5J 2N3 (Canada); Xingfang, Li [Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, 10-102 Clinical Sciences Building, Edmonton, Alberta, T6G 2G3 (Canada); Environmental Health Sciences, Department of Public Health Sciences, School of Public Health, University of Alberta, 10-102 Clinical Sciences Building, Edmonton, Alberta, T6G 2G3 (Canada)], E-mail: xingfang.li@ualberta.ca

    2008-05-12

    A cell-microelectronic sensing technique is developed for profiling chemical cytotoxicity and is used to study different cytotoxic effects of the same class chemicals using nitrosamines as examples. This technique uses three human cell lines (T24 bladder, HepG2 liver, and A549 lung carcinoma cells) and Chinese hamster ovary (CHO-K1) cells in parallel as the living components of the sensors of a real-time cell electronic sensing (RT-CES) method for dynamic monitoring of chemical toxicity. The RT-CES technique measures changes in the impedance of individual microelectronic wells that is correlated linearly with changes in cell numbers during t log phase of cell growth, thus allowing determination of cytotoxicity. Four nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosodiphenylamine (NDPhA), N-nitrosopiperidine (NPip), and N-nitrosopyrrolidine (NPyr), were examined and unique cytotoxicity profiles were detected for each nitrosamine. In vitro cytotoxicity values (IC{sub 50}) for NDPhA (ranging from 0.6 to 1.9 mM) were significantly lower than the IC{sub 50} values for the well-known carcinogen NDMA (15-95 mM) in all four cell lines. T24 cells were the most sensitive to nitrosamine exposure among the four cell lines tested (T24 > CHO > A549 > HepG2), suggesting that T24 may serve as a new sensitive model for cytotoxicity screening. Cell staining results confirmed that administration of the IC{sub 50} concentration from the RT-CES experiments inhibited cell growth by 50% compared to the controls, indicating that the RT-CES method provides reliable measures of IC{sub 50}. Staining and cell-cycle analysis confirmed that NDPhA caused cell-cycle arrest at the G0/G1 phase, whereas NDMA did not disrupt the cell cycle but induced cell death, thus explaining the different cytotoxicity profiles detected by the RT-CES method. The parallel cytotoxicity profiling of nitrosamines on the four cell lines by the RT-CES method led to the discovery of the unique cytotoxicity of NDPh

  1. Teaching seven principles for public health ethics: towards a curriculum for a short course on ethics in public health programmes.

    Science.gov (United States)

    Schröder-Bäck, Peter; Duncan, Peter; Sherlaw, William; Brall, Caroline; Czabanowska, Katarzyna

    2014-10-07

    Teaching ethics in public health programmes is not routine everywhere - at least not in most schools of public health in the European region. Yet empirical evidence shows that schools of public health are more and more interested in the integration of ethics in their curricula, since public health professionals often have to face difficult ethical decisions. The authors have developed and practiced an approach to how ethics can be taught even in crowded curricula, requiring five to eight hours of teaching and learning contact time. In this way, if programme curricula do not allow more time for ethics, students of public health can at least be sensitised to ethics and ethical argumentation. This approach - focusing on the application of seven mid-level principles to cases (non-maleficence, beneficence, health maximisation, efficiency, respect for autonomy, justice, proportionality) - is presented in this paper. Easy to use 'tools' applying ethics to public health are presented. The crowded nature of the public health curriculum, and the nature of students participating in it, required us to devise and develop a short course, and to use techniques that were likely to provide a relatively efficient introduction to the processes, content and methods involved in the field of ethics.

  2. Fundamentalism in Psychological Science. The Publication Manual as "Bible."

    Science.gov (United States)

    Walsh-Bowers, Richard

    1999-01-01

    Analyzes the content of the fourth edition of the "Publication Manual of the American Psychological Association" (1994) as if it were a biblical text. Draws on socio-historical studies and critical feminist perspectives to discuss the manual's function as a fundamentalist "bible" in relation to psychologists' culture. (SLD)

  3. Ethics in Ethnobiology Publication

    Directory of Open Access Journals (Sweden)

    James R. Welch

    2012-12-01

    Full Text Available With the recent multiplication of traditional and electronic venues for publishing in ethnobiology, the social sciences, the life sciences, and related fields, it is increasingly important that authors practice self-diligence to ensure that the contents of their publications meet criteria of veracity and ethical soundness. Although the peer-review process encourages high standards, it is an insufficient means for verifying the ethical worthiness of most publications. The ethical merits of published research derive from a cumulative process including formulating a research design, obtaining permissions, collecting and analyzing data, and finally composing and submitting a manuscript. Unfortunately, there is no failsafe ethical gatekeeper at any stage of the process. The importance of ethical publishing is all the more important in the field of ethnobiology, as professionals in the field  often cross the intellectual and methodological boundaries between disciplines, and their research often involves multiple stakeholders in widespread jurisdictions.

  4. [The role of the public health personnel in the Prevention Department (in the Hygiene Services and Public Health Care and Hygiene of Food and Nutrition): proposal for the future of public health care].

    Science.gov (United States)

    Brusaferro, Silvio; Marcolongo, Adriano; Schiava, Flavio; Bggio, Luca; Betta, Alberto; Buzzo, Armando; Cinquetti, Sandro; Coin, Paulo; Dal Fior, Tina; De Battisti, Fabio; De Marchi, Chiara; De Noni, Lucia; Donatoni, Luigi; Ferraresso, Anna; Gallo, Giovanni; Gallo, Lorenza; Gallo, Tolinda; Gottardello, Lorena; Menegon, Tiziana; Minuzzo, Michele; Paussi, Gianna; Pinna, Clara; Poli, Albino; Rossato, Luigi; Sbrogliò, Luca; Simeoni, Josef; Speccini, Manuela; Stoppato, Ugo; Superbi, Piero; Tardivo, Stefano; Urdich, Alessandro; Valsecchi, Massimo; Zamparo, Manuela

    2008-01-01

    A global and local discussion on Public Health relevance is taking place, including the future role and organization of its services. Noteworthy becomes the role played by Public Health Specialists. This work presents the results of a workshop, carried out following the Guilbert methodology, whose aim was to define Public Health Doctors functions and their related activities. The programme involved 30 professionals from Triveneto area (North Eastern Italy), working in Prevention Departments at National Health Service and Universities. The key-functions identified were: 1) Health status assessment and identification of community risk factors, 2) Health Promotion, 3) Prevention, 4) Protection, 5) Planning, 6) Communication, 7) Professional Training, 8) Alliances and resources for complex Public Health programs, 9) Crisis management in Public Health, 10) Research. For each function activities were identified, meaning concerning areas and contents that must be warranted by professionals. This experience allowed to share existing attitudes and experiences present in Triveneto area, and it can stand as a feasible instrument for different settings. Nevertheless, it appears mandatory explaining at each level in the society role and functions of Prevention Departments.

  5. Information Seeking in Social Media: A Review of YouTube for Sedentary Behavior Content.

    Science.gov (United States)

    Knight, Emily; Intzandt, Brittany; MacDougall, Alicia; Saunders, Travis J

    2015-01-20

    The global prevalence of sedentary lifestyles is of grave concern for public health around the world. Moreover, the health risk of sedentary behaviors is of growing interest for researchers, clinicians, and the general public as evidence demonstrates that prolonged amounts of sedentary time increases risk for lifestyle-related diseases. There is a growing trend in the literature that reports how social media can facilitate knowledge sharing and collaboration. Social sites like YouTube facilitate the sharing of media content between users. The purpose of this project was to identify sedentary behavior content on YouTube and describe features of this content that may impact the effectiveness of YouTube for knowledge translation. YouTube was searched on a single day by 3 independent reviewers for evidence-based sedentary behavior content. Subjective data (eg, video purpose, source, and activity type portrayed) and objective data (eg, number of views, comments, shares, and length of the video) were collected from video. In total, 106 videos met inclusion criteria. Videos were uploaded from 13 countries around the globe (ie, Australia, Barbados, Belgium, Canada, Colombia, Kenya, New Zealand, Russia, South Africa, Spain, Ukraine, United Kingdom, United States). The median video length was 3:00 minutes: interquartile range (IQR) 1:44-5:40. On average, videos had been on YouTube for 15.0 months (IQR 6.0-27.5) and had been viewed 239.0 times (IQR 44.5-917.5). Videos had remarkably low numbers of shares (median 0) and comments (median 1). Only 37.7% (40/106) of videos portrayed content on sedentary behaviors, while the remaining 66 videos portrayed physical activity or a mix of behaviors. Academic/health organizations (39.6%, 42/106) and individuals (38.7%, 41/106) were the most prevalent source of videos, and most videos (67.0%, 71/106) aimed to educate viewers about the topic. This study explored sedentary behavior content available on YouTube. Findings demonstrate that

  6. A study of real-time content marketing : formulating real-time content marketing based on content, search and social media

    OpenAIRE

    Nguyen, Thi Kim Duyen

    2015-01-01

    The primary objective of this research is to understand profoundly the new concept of content marketing – real-time content marketing on the aspect of the digital marketing experts. Particularly, the research will focus on the real-time content marketing theories and how to build real-time content marketing strategy based on content, search and social media. It also finds out how marketers measure and keep track of conversion rates of their real-time content marketing plan. Practically, th...

  7. The use of international television formats by public-service broadcasters in Australia, Denmark and Germany

    DEFF Research Database (Denmark)

    Esser, Andrea; Jensen, Pia Majbritt

    2015-01-01

    the provision of content that informs and educates, helps imagine the nation, enriches the lives and culture of its citizens and provides an inclusive public sphere to support democracy. Can internationally franchised programmes fulfil these remits? And to what extent are they employed by public service...

  8. Content, Accessibility, and Dissemination of Disaster Information via Social Media During the 2016 Louisiana Floods.

    Science.gov (United States)

    Scott, Katherine K; Errett, Nicole A

    2017-12-27

    Social media is becoming increasingly integrated into disaster response communication strategies of public health and emergency response agencies. We sought to assess the content, accessibility, and dissemination of social media communications made by government agencies during a disaster response. A cross-sectional analysis of social media posts made by federal, state, and local government, public health and emergency management agencies before, during, and after the 2016 Louisiana floods was conducted to determine their content, accessibility, and dissemination by level of government and time relative to disaster onset. Facebook and/or Twitter posts made by public agencies involved in the response to the 2016 Louisiana Flooding events (FEMA Disaster Declaration [DR-4277]) published between August 4 and September 16, 2016, publicly available online between February 21 and March 31, 2017, were included in the analysis. Content: The text of each post was assessed to determine whether it contained information on provision of situational awareness; addressing misconception, actionable requests; mental, behavioral, and emotional support; and/or recovery and rebuilding resources. Accessibility: A Flesh-Kincaid grade level of each post was calculated, and information on post language, originality, hyperlinks, visuals, videos, or hash tag was recorded. Dissemination: The average number of reacts/likes, shares/retweets, and comments per post was calculated. Most posts contained information related to situational awareness and recovery resources. There was an increase in messages during the first week of the disaster at all levels. Few posts were made in languages other than English. Compared with state and federal posts, local Facebook posts averaged fewer reacts, comments, and shares throughout the analysis period. Government agencies may maximize the use of social media platforms for disaster communications by establishing their social media network in advance of a

  9. Public health in the 21st century: working differently means leading and learning differently.

    Science.gov (United States)

    Czabanowska, Katarzyna; Rethmeier, Kenneth A; Lueddeke, George; Smith, Tony; Malho, André; Otok, Robert; Stankunas, Mindaugas

    2014-12-01

    Public health needs to adapt to the complex context of 21st century Europe. Unquestionably, leaders for health require new skills to face a myriad of wicked problems and challenges that are at a critical juncture for potential improvements. Public health curricula are traditionally oriented around core educational disciplines, and there is little room for developing students' leadership capabilities within the context of public health. The aim is to present the meaning of contemporary public health leadership based on qualitative research and propose a curriculum model for contemporary public health leadership. A series of in-depth semi-structured interviews were carried out with six European public health leaders from a variety of countries and professional backgrounds. The interviews recorded and transcribed. A thematic content analysis was undertaken to identify themes within the data. Five common themes that help to inform future leadership capacity arose from the interviews: the inner path of leadership, the essence of leadership, new types of leadership, future leaders' imperatives functioning within a complex and uncertain European public health context. The leadership thematic model makes an important contribution to defining public health leadership in Europe and can help to guide the content development of public health leadership curricula. The authors assert that a new 'integrative inquiry-based learning model', with leadership as a central component, will allow schools and departments of public health across Europe to be able to ensure that tomorrow's public health leaders are adequately trained and prepared for the challenges they will face. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  10. Education for Public Health Capacity in the Nursing Workforce: Findings from a Review of Education and Practice Issues.

    Science.gov (United States)

    Latter, Sue; Speller, Viv; Westwood, Greta; Latchem, Susan

    2003-01-01

    Literature review and interviews with nine public health and nursing education informants in Britain indicated that, although National Health Service policy highlights public health, clinical placements in this area are limited and curriculum content needs to be applicable to public health. Needs assessments show skills gaps in practicing nurses…

  11. Nuclear public information activities in Chile; Programa de educacion publica de la energia nuclear en Chile

    Energy Technology Data Exchange (ETDEWEB)

    Munoz Quintana, R [Comision Chilena de Energia Nuclear, Santiago (Chile)

    1995-10-01

    Nuclear plans and developing programs in developing and developed countries are facing-in a higher or lower degree- opposition from public opinion. The objectives and contents of the public education program on nuclear energy in Chile are dealt with in this paper.

  12. Radiation protection, public policies and education

    International Nuclear Information System (INIS)

    Alves, Simone F.; Jacomino, Vanusa M.F.; Barreto, Alberto A.

    2011-01-01

    The objective of this paper is to inform about the aspects of radiation protection public policies concerning the public spheres and the ordinary population. It is known that information has been considered a very important good in several knowledge areas. However, the efficiency of their transmission mechanisms should be periodically evaluated, checking existing critical and stagnation points. Nuclear area can be mentioned as a historically typical case, where the public policies assume relevant importance as tool for promotion, control and education of the population in general. Considering the polemic nature of such subject, it is clear that there is a need for conducting the construction of educational contents taking in account the educator training necessities. The addressing of radiation protection aspects applied to nuclear techniques conducts, for example, to the awareness on the benefits of radiation and its industrial and medical applications, which are established considering the worldwide adopted basic principles of radiation protection. Such questions, concerned with (or related to) public policies, establish a link between radiation protection and education, themes explored in this article to provide a better view of the current Brazilian scenario. (author)

  13. MACRO-PUBLIC RELATIONS: CRISIS COMMUNICATION IN THE AGE OF INTERNET

    OpenAIRE

    Zhongxuan Lin; Yujuan Guo; Yingying Chen

    2013-01-01

    In order to study the crisis communication in the age of Internet, the study takes the battle between two Internet companies, Tencent and Qihoo, as a case study, but focuses more on their huge public audiences, which may be defined as a “macro-public” crowd. The study employs multiple research methods including survey, focus groups interviews and content analysis to explore their “macro-public relations” which may be driven by the spiral of silence and crowd psychology. This dynamic undergrou...

  14. “Less Than A Wife”: A Study of Polycystic Ovary Syndrome Content in Teen and Women’s Digital Magazines

    Science.gov (United States)

    Jones, Hillary

    2016-01-01

    Background Polycystic ovary syndrome (PCOS) is a major public health problem that affects women’s physical and mental health. According to the US National Institutes of Health Office of Disease Prevention, there is a need to improve public awareness of the syndrome among health care providers and the public. Women’s magazines are a type of “edutainment” that publish health content in addition to beauty, fashion, and entertainment content. These media have the potential to expose primarily female readers to content on PCOS and influence readers’ beliefs and attitudes about women with PCOS. Objective The objective of this study was to explore how digital (online) teen and women’s magazines portray women with PCOS. Methods We used data from the Alliance for Audited Media to identify popular digital teen and women’s magazines with circulation rates ≥1,000,001. We also included magazines with circulation rates 100,001–1,000,000 directed toward racial and ethnic minority readers. A search of magazine websites over a 1-month period in 2015 yielded 21 magazines (eg, Glamour, Cosmopolitan en Español, Essence, and O, The Oprah Magazine) and 170 articles containing “PCOS” and “polycystic ovary syndrome.” Textual analysis using a grounded theory approach was used to identify themes. Results Articles depicted PCOS symptoms as a hindrance to women’s social roles as wives and mothers and largely placed personal responsibility on women to improve their health. To a lesser extent, women were depicted as using their personal experience with PCOS to advocate for women’s health. Experiences of Latina and African American women and adolescents with PCOS were absent from women’s magazine articles. Conclusions The findings can inform health education programs that teach women to be critical consumers of PCOS-related content in digital women’s magazines. Future research on PCOS content in digital teen and women’s magazines can help researchers

  15. Determination of Mineral Contents in Unpolished Rice and Bean Samples by Neutron Activation Analysis

    International Nuclear Information System (INIS)

    Moon, J. H.; Kim, S. H.; Baek, S. Y.; Chung, Y. S.

    2012-01-01

    As scientists have focused their researches on the health impacts caused by mineral nutrient deficiencies and hazardous elements, public concern regarding mineral intake from dietary food is rising. In this reason, the dietary habits of Koreans have been shifted from white rice to more nutrient rice like unpolished rice and rice mixed with beans. It is known that unpolished rice and beans contain more protein, vitamin and mineral contents than white rice and are more beneficial to human health, even though they sometimes cause indigestion or allergy. The objectives of this study were to determine the mineral contents in unpolished rice and bean samples by a neutron activation analysis (NAA) and to compare the level of mineral contents between the samples

  16. Determination of Mineral Contents in Unpolished Rice and Bean Samples by Neutron Activation Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Moon, J. H.; Kim, S. H.; Baek, S. Y.; Chung, Y. S. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    As scientists have focused their researches on the health impacts caused by mineral nutrient deficiencies and hazardous elements, public concern regarding mineral intake from dietary food is rising. In this reason, the dietary habits of Koreans have been shifted from white rice to more nutrient rice like unpolished rice and rice mixed with beans. It is known that unpolished rice and beans contain more protein, vitamin and mineral contents than white rice and are more beneficial to human health, even though they sometimes cause indigestion or allergy. The objectives of this study were to determine the mineral contents in unpolished rice and bean samples by a neutron activation analysis (NAA) and to compare the level of mineral contents between the samples

  17. Trustee Essentials: A Handbook for Wisconsin Public Library Trustees.

    Science.gov (United States)

    Wisconsin State Dept. of Public Instruction, Madison.

    This handbook for Trustees of the Wisconsin Public Library describes in detail the tasks involved in being a library trustee. The handbook comprises a number of "Trustee Essentials" that cover the basic essential information needed by Trustees, as well as sources of additional information. Contents include: The Trustee Job Description;…

  18. Developing a comprehensive curriculum for public health advocacy.

    Science.gov (United States)

    Hines, Ayelet; Jernigan, David H

    2012-11-01

    There is a substantial gap in public health school curricula regarding advocacy. Development of such a curriculum faces three challenges: faculty lack advocacy skills and experience; the public health literature on effective advocacy is limited; and yet a successful curriculum must be scalable to meet the needs of approximately 9,000 public health students graduating each year. To meet these challenges, we propose a 100-hour interactive online curriculum in five sections: campaigning and organizing, policy making and lobbying, campaign communications, new media, and fund-raising. We outline the content for individual modules in each of these sections, describe how the curriculum would build on existing interactive learning and social media technologies, and provide readers the opportunity to "test-drive" excerpts of a module on "grasstops" organizing. Developing advocacy skills and expertise is critical to meeting the challenges of public health today, and we provide a blueprint for how such training might be brought to scale in the field.

  19. Online tables of contents for books: effect on usage*

    Science.gov (United States)

    Morris, Ruth C.

    2001-01-01

    Objectives: To explore whether the presence of online tables of contents (TOC) in an online catalog affects circulation (checkouts and inhouse usage). Two major questions were posed: (1) did the presence of online tables of contents for books increase use, and, (2) if it did, what factors might cause the increase? Method: A randomized and stratified design was used in tracking usage of 3,957 book titles that were previously divided into two groups: one with TOC and one without TOC. Stratification was done for year of imprint, location, subject, previous use, circulating or non-circulating status, and presence of TOC. The use was tracked by the online catalog statistics in the InnoPac online catalog for fourteen months. Results: The study found that tables of contents do increase usage. It also showed a correlation in the size of the effect based on the currency of the titles. In general, even after adjusting for all of the variables (publication date, location, circulation status, subject, and previous use), the odds of a title being used increased by 45% if the titles had online tables of contents, a statistically significant impact at the 0.05 level. Conclusions: This case-control study presents new information about the impact on circulation and inhouse use when tables of contents for books are added to the online catalog record. The study helps to establish the positive role of tables of contents in online catalogs. The research establishes TOC as a major parameter that can be successfully studied using quantitative methods. The study also provides information professionals with some guidance on when enhancement of TOC is likely to be most effective in increasing the use of existing collections. PMID:11209798

  20. Training physician investigators in medicine and public health research.

    Science.gov (United States)

    Gourevitch, Marc N; Jay, Melanie R; Goldfrank, Lewis R; Mendelsohn, Alan L; Dreyer, Benard P; Foltin, George L; Lipkin, Mack; Schwartz, Mark D

    2012-07-01

    We have described and evaluated the impact of a unique fellowship program designed to train postdoctoral, physician fellows in research at the interface of medicine and public health. We developed a rigorous curriculum in public health content and research methods and fostered linkages with research mentors and local public health agencies. Didactic training provided the foundation for fellows' mentored research initiatives, which addressed real-world challenges in advancing the health status of vulnerable urban populations. Two multidisciplinary cohorts (6 per cohort) completed this 2-year degree-granting program and engaged in diverse public health research initiatives on topics such as improving pediatric care outcomes through health literacy interventions, reducing hospital readmission rates among urban poor with multiple comorbidities, increasing cancer screening uptake, and broadening the reach of addiction screening and intervention. The majority of fellows (10/12) published their fellowship work and currently have a career focused in public health-related research or practice (9/12). A fellowship training program can prepare physician investigators for research careers that bridge the divide between medicine and public health.

  1. Naturalising Representational Content

    Science.gov (United States)

    Shea, Nicholas

    2014-01-01

    This paper sets out a view about the explanatory role of representational content and advocates one approach to naturalising content – to giving a naturalistic account of what makes an entity a representation and in virtue of what it has the content it does. It argues for pluralism about the metaphysics of content and suggests that a good strategy is to ask the content question with respect to a variety of predictively successful information processing models in experimental psychology and cognitive neuroscience; and hence that data from psychology and cognitive neuroscience should play a greater role in theorising about the nature of content. Finally, the contours of the view are illustrated by drawing out and defending a surprising consequence: that individuation of vehicles of content is partly externalist. PMID:24563661

  2. To make files of projects of some non-noticeable modifications of base nuclear installations (INB) available to the public

    International Nuclear Information System (INIS)

    Vial, Eugenie

    2013-01-01

    As the French Nuclear Safety Authority (ASN) published a decision related to the availability to the public of files of projects of modifications as specified in the French Code of the Environment, the author proposes an analysis of this decision. He discusses its scope of application within a legal and regulatory context at the crossroad of nuclear and environmental issues, and indicates the procedures concerned by this decision. He outlines the content of the files which the operator must transmit to the ASN: the modification request file, the public availability file. He indicates the operations which must be performed prior to public availability, the content of the notice of availability, and the conditions of information of the local information commission (CLI) and of the advert of public availability. He presents the various operations to be performed after the public availability

  3. [Written and pictorial content in magazines and their possible relationship to eating disorders].

    Science.gov (United States)

    Szabó, Kornélia; Túry, Ferenc

    2012-02-01

    In the current study we reviewed the literature on studies exploring the magazine reading frequency, written and pictorial contents appearing in magazines and their connection to eating disorders. Reading different fashion and fitness magazines has effect on readers through several indirect and direct factors and through trustable and false information. They affect readers' body satisfaction, self-esteem, eating habits and more generally their health behavior. Different theories have been explained to account for these associations and several other studies examined empirically the connection between the frequency of magazine reading and eating disorders, as well as the symptoms leading to eating disorders. We analyzed and summarized articles between 1975 and 2009 from online databases. We used the following sources: Science Direct (http://www.sciencedirect.com/), Springer-Verlag GmbH (http://www.springerlink.com/) and SAGE Publications Ltd (http://online.sagepub. com/). The pictorial and written magazine contents were associated with the development and maintenance of eating disorders or with symptoms that might lead to eating disorders. The publications compared to previous years featured an increased number of advertisements for unhealthy foods, for unhealthy radical diet plans and exercise programs. Furthermore the magazines contained conflicting messages about nutrition, body functions and eating disorders. Written and pictorial magazine contents, messages might increase the risk for development of eating disorders, especially in vulnerable individuals.

  4. Smoking cessation apps for smartphones: content analysis with the self-determination theory.

    Science.gov (United States)

    Choi, Jounghwa; Noh, Ghee-Young; Park, Dong-Jin

    2014-02-12

    Smartphones are increasingly receiving attention from public health scholars and practitioners as a means to assist individuals' health management. A number of smartphone apps for smoking cessation are also available; however, little effort has been made to evaluate the content and functions of these apps employing a theoretical framework. The present study aims to analyze and evaluate the contents of smoking cessation apps available in South Korea employing the self-determination theory (SDT) as a theoretical framework for analysis. This study analyzes the extent to which smoking cessation apps have features that satisfy the basic needs identified in the SDT, which stimulate autonomous motivation. The type of motivational goal content manifested in the apps and how the goal content was framed are also explored. By assessing the features of smoking cessation apps based on the SDT, this study aims to offer direction for improvement for these apps. Out of 309 apps identified from the iTunes store and Google Play (excluding 27 duplications), 175 apps were randomly drawn and analyzed. The coding scheme was drafted by the authors based on the SDT and gain/loss framing theory and was further finely tuned through the process of coder training and by establishing intercoder reliability. Once the intercoder reliability was established, the coders divided up the rest of the sample and coded them independently. The analysis revealed that most apps (94.3%, 165/175) had at least one feature that tapped at least 1 of the 3 basic needs. Only 18 of 175 apps (10.3%) addressed all 3 basic needs. For goal content, money (53.7%, 94/175) showed the highest frequency, followed by health (32.0%, 56/175), time (7.4%, 13/175), and appearance (1.1%, 2/175), suggesting that extrinsic goals are more dominantly presented in smoking cessation apps. For the framing of goal content, gain framing appeared more frequently (41.7%, 73/175). The results suggest that these smoking cessation apps may

  5. Content Model Use and Development to Redeem Thin Section Records

    Science.gov (United States)

    Hills, D. J.

    2014-12-01

    The National Geothermal Data System (NGDS) is a catalog of documents and datasets that provide information about geothermal resources located primarily within the United States. The goal of NGDS is to make large quantities of geothermal-relevant geoscience data available to the public by creating a national, sustainable, distributed, and interoperable network of data providers. The Geological Survey of Alabama (GSA) has been a data provider in the initial phase of NGDS. One method by which NGDS facilitates interoperability is through the use of content models. Content models provide a schema (structure) for submitted data. Schemas dictate where and how data should be entered. Content models use templates that simplify data formatting to expedite use by data providers. These methodologies implemented by NGDS can extend beyond geothermal data to all geoscience data. The GSA, using the NGDS physical samples content model, has tested and refined a content model for thin sections and thin section photos. Countless thin sections have been taken from oil and gas well cores housed at the GSA, and many of those thin sections have related photomicrographs. Record keeping for these thin sections has been scattered at best, and it is critical to capture their metadata while the content creators are still available. A next step will be to register the GSA's thin sections with SESAR (System for Earth Sample Registration) and assign an IGSN (International Geo Sample Number) to each thin section. Additionally, the thin section records will be linked to the GSA's online record database. When complete, the GSA's thin sections will be more readily discoverable and have greater interoperability. Moving forward, the GSA is implementing use of NGDS-like content models and registration with SESAR and IGSN to improve collection maintenance and management of additional physical samples.

  6. Digital Content Strategies

    OpenAIRE

    Halbheer, Daniel; Stahl, Florian; Koenigsberg, Oded; Lehmann, Donald R

    2013-01-01

    This paper studies content strategies for online publishers of digital information goods. It examines sampling strategies and compares their performance to paid content and free content strategies. A sampling strategy, where some of the content is offered for free and consumers are charged for access to the rest, is known as a "metered model" in the newspaper industry. We analyze optimal decisions concerning the size of the sample and the price of the paid content when sampling serves the dua...

  7. The role of content marketing in social media content communities

    OpenAIRE

    Charmaine du Plessis

    2017-01-01

    Background: Content marketing has become a leading marketing technique in digital marketing communication and uses the point of view of consumers to build relationships by creating and sharing engaging content in social media that enhance their daily lives. Existing research on social media communities has focused mainly on social media marketing and virtual brand community perspectives while content marketing’s valuable and unobtrusive role in social media content communities has largely bee...

  8. Public concerns about transboundary haze: a comparison of Indonesia, Singapore, and Malaysia

    OpenAIRE

    Tim Forsyth

    2014-01-01

    Public concerns about environmental problems create narrative structures that influence policy by allocating roles of blame, responsibility, and appropriate behavior. This paper presents an analysis of public concerns about transboundary haze resulting from forest fires in Indonesia, Singapore, and Malaysia for crises experienced in 1997, 2005 and 2013. The source of the information is content analysis of 2231 articles from representative newspapers in each country. The study shows that newsp...

  9. Product development public-private partnerships for public health: a systematic review using qualitative data.

    Science.gov (United States)

    De Pinho Campos, Katia; Norman, Cameron D; Jadad, Alejandro R

    2011-10-01

    Almost a decade ago, public health initiated a number of innovative ventures to attract investments from multinational drug companies for the development of new drugs and vaccines to tackle neglected diseases (NDs). These ventures - known as product development public-private partnerships (PD PPPs) - represent the participation of the public and private actors toward the discovery and development of essential medicines to reduce the suffering of over one billion people worldwide living with NDs. This systematic review aimed to identify empirical-based descriptive articles to understand critical elements in the partnership process, and propose a framework to shed light on future guidelines to support better planning, design and management of existing and new forms of PPPs for public health. Ten articles met the inclusion criteria and were analyzed and synthesized using qualitative content analysis. The findings show that the development stage of PD PPPs requires a careful initiation and planning process including discussion on values and shared goals, agreement on mutual interests & equality of power relation, exchange of expertise & resources, stakeholder engagement, and assessment of the local health capacity. The management stage of PD PPPs entails transparency, extensive communication and participatory decision-making among partner organizations. This review illustrates the difficulties, challenges and effective responses during the partnering process. This model of collaboration may offer a way to advance population health at present, while creating streams of innovation that can yield future social and financial dividends in enhancing the public's health more widely. Copyright © 2011 Elsevier Ltd. All rights reserved.

  10. Technological feasibility of preserving meat, poultry and fish products by using a combination of conventional additives, mild heat treatment and irradiation

    International Nuclear Information System (INIS)

    Wierbicki, E.

    1981-01-01

    Radappertization is particularly applicable to precooked meat, poultry, fin fish, and shellfish, as well as to dry foods, animal feed, and spices. The resulting radappertized products are free from food spoilage microorganisms and organisms of public health significance, including the pathogens such as C. botulinum, salmonellae, trichinae, etc. The radappertized products can be stored without refrigeration for long periods (years), the limiting factor being the integrity of the primary packaging material. Irradiation sterilization of cured meats allows complete elimination or a drastic reduction of incoming nitrite to the levels needed only for characteristic colour and flavour of the items while providing protection against C. botulinum by irradiation. The irradiated-cured products with the low levels of added nitrite are free from residual nitrite and nitrosamines, including nitrosopyrrolidine in fried bacon. In recent co-operative research with the US Department of Agriculture, it was shown that irradiation also destroys pre-formed nitrosamines in bacon. The technology of the process was developed by the US National Food Irradiation Program and the US Army from 1953 to 1980. The US Army spearheaded the development of this new technology to the point where the food irradiation potentials have become meaningful within the broad scope of national and international interests. Therefore, it was highly appropriate that, effective 1 October 1980, the responsibility for the programme at this stage was transferred to the US Department of Agriculture which has been designated as the leading agency for the US Federal food and nutrition programmes

  11. Triphenylamine - a 'new' stabilizer for nitrocellulose based propellants. Pt. 1: chemical stability studies

    Energy Technology Data Exchange (ETDEWEB)

    Wilker, Stephan; Heeb, Gerhard [WIWEB ASt Heimerzheim, Grosses Cent, 53913 Swisttal (Germany); Vogelsanger, Beat [Nitrochemie Wimmis AG, Niesenstr. 44, 3752 Wimmis (Switzerland); Petrzilek, Jan; Skladal, Jan [Explosia a.s. - Research Institute of Industrial Chemistry (VUPCH), 532 17 Pardubice (Czech Republic)

    2007-04-15

    Triphenylamine (TPA) was used for the first time in France in 1937 as a stabilizer for propellants. The stability of those samples was described as 'good'. Around 1950 an American group produced TPA stabilized propellants and investigated the decomposition mechanism. Apart from one single experiment in the 1970s no further attempts were made to take TPA as a stabilizer for propellants. With the background of an increasingly critical discussion about nitrosamines in propellants and their declaration of being carcinogenic, TPA revealed a renaissance since the year 2000. To achieve the goal of nitrosamine free propellants several TPA stabilized propellants were produced. Their processability, stability and ballistic properties were investigated. This publication summarizes the most important results of stability tests on more than 30 different TPA stabilized propellants including the decomposition mechanism, the synthesis of the consecutive products and their stabilizing properties. In addition, the internal compatibility of TPA with the most important propellant ingredients is discussed and its relative decomposition rate is compared with that of other stabilizers. In summary TPA is a suitable stabilizer for propellants. It has nevertheless two disadvantages. It is relatively rapidly consumed in double base formulations (which makes it difficult to pass the criteria of AOP-48, Ed. 2) and the stabilizing activity of the two major consecutive products 4-NO{sub 2}-TPA and especially 4,4{sup '}-di-NO{sub 2}-TPA is low. (Abstract Copyright [2007], Wiley Periodicals, Inc.)

  12. Publications in Cuba after Latin American Independences

    Directory of Open Access Journals (Sweden)

    Juan José SÁNCHEZ BAENA

    2011-04-01

    Full Text Available This article has a double objective. On the one hand, it aims to offer a vision of the consequences of the liberal Triennium, and the end of Spanish domain in continental America, on the Cuban printing culture. On the other hand, it analyses the main aspects that influenced Cuban society through the most important periodical contents. The extraordinary economic and commercial development, whose most influential agent was the economic group denominated «sacarocracia», made the printing evolution unstoppable, despite the strong control and censorship imposed by the Spanish government fearing the independence of near Republics. Some new serial publications with good content appeared, such as Revista Bimestre Cubana, and the expansion of printing slowly began in new Cuban populations.

  13. Aging Education in the Public Schools--Coming of Age?

    Science.gov (United States)

    Hoot, James L.; Lumsden, D. Barry

    A statewide survey of elementary and secondary teachers in Texas indicates that little attention is currently given to direct teaching about aging or to integrating this content area into the school curriculum. The following questions were asked: (1) To what extent is aging incorporated into the public school curricula? (2) Would increased…

  14. The Reflection of Social Values in Public School Reading Textbooks in the United States: A Critical Content Analysis

    Science.gov (United States)

    Stockdale, Christopher L.

    2015-01-01

    In light of the recently published Common Core State Standards Initiative, public school curriculum has once again come under scrutiny. While curriculum debates have taken place since the very beginnings of public schooling in the United States, too few have taken more than a passing notice of the textbooks that, in many cases, comprise the…

  15. The Use of Format Adaptation in Danish Public Service Programming

    DEFF Research Database (Denmark)

    Jensen, Pia Majbritt

    2013-01-01

    The article investigates Danish public service broadcasters’ use of format adaptations over a 12-year period in order to examine claims that formats constitute a potential threat to public service broadcasting and the national Danish television industry and culture. The article’s findings, howeve...... service orientation. Instead the article argues, following German sociologist Ulrich Beck, that format adaptation can represent a form of ‘banal transnationalism’, pointing to the fact that the world is no longer exclusively defined by national boundaries.......The article investigates Danish public service broadcasters’ use of format adaptations over a 12-year period in order to examine claims that formats constitute a potential threat to public service broadcasting and the national Danish television industry and culture. The article’s findings, however......, bear little evidence to support these claims. The practice of format adaptation constitutes a comparatively small proportion of the overall production of Danish public service content, and, more importantly, most of the formats adapted by the public broadcasters have a comparatively solid public...

  16. [Postgraduate studies in public health: the problem of efficiency evaluation].

    Science.gov (United States)

    Boczkowski, Andrzej

    2003-01-01

    The satisfaction of customer is the main measure and the most important, generally recognized criterion for evaluating the quality of products and services. In the case of education and training, the quality is frequently understood as effectiveness, i.e., the degree to what educational objectives of a training institution are met; the objectives previously formulated on the basis of analyzed and defined demands and expectations of customers (clients). In the first part of the paper: (1) the problems related to the question who in fact is the customer in the context of an institution providing education in public health are discussed; (2) a proposal for resolving these problems is presented; and (3) the main directions of evaluation activities, which should be undertaken under monitoring and effectiveness assessment of postgraduate training in public health are pointed out. In the years 1998-2002, the students' assessment data on educational programs, curriculum contents and subject teachers in the field of postgraduate studies in the School of Public Health, Nofer Institute of Occupational Medicine, Łódź, were collected with the help of specially-designed evaluation questionnaires. The data on the students' self-assessment of gained professional competencies were also collected. All students who completed the School of Public Health in these years were subjected to the evaluation inquiries. The data collected were analyzed. Due to the analysis it was possible to define: the quality of the curriculum contents, as well as the professional and didactic skills of the teaching staff as perceived by the students; the degree to what particular curriculum in public health contributed to the increase in professional competence as perceived by the students; the degree to what particular teaching subjects influenced the students' knowledge of and skills in Public Health. The results obtained provided information very useful in the teaching process, designing of

  17. Myonuclear transcription is responsive to mechanical load and DNA content but uncoupled from cell size during hypertrophy.

    Science.gov (United States)

    Kirby, Tyler J; Patel, Rooshil M; McClintock, Timothy S; Dupont-Versteegden, Esther E; Peterson, Charlotte A; McCarthy, John J

    2016-03-01

    Myofibers increase size and DNA content in response to a hypertrophic stimulus, thus providing a physiological model with which to study how these factors affect global transcription. Using 5-ethynyl uridine (EU) to metabolically label nascent RNA, we measured a sevenfold increase in myofiber transcription during early hypertrophy before a change in cell size and DNA content. The typical increase in myofiber DNA content observed at the later stage of hypertrophy was associated with a significant decrease in the percentage of EU-positive myonuclei; however, when DNA content was held constant by preventing myonuclear accretion via satellite cell depletion, both the number of transcriptionally active myonuclei and the amount of RNA generated by each myonucleus increased. During late hypertrophy, transcription did not scale with cell size, as smaller myofibers (transcriptional activity. Finally, transcription was primarily responsible for changes in the expression of genes known to regulate myofiber size. These findings show that resident myonuclei possess a significant reserve capacity to up-regulate transcription during hypertrophy and that myofiber transcription is responsive to DNA content but uncoupled from cell size during hypertrophy. © 2016 Kirby et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  18. The Issue of the Public Space – Pornography of Contemporary and new Media

    Directory of Open Access Journals (Sweden)

    Divna Vuksanović

    2014-05-01

    Full Text Available The text examines the relationship “intimate”, “private” and “public” space in the field of contemporary media. Questioning begins with the medium photography, to complete the research in the field of activity of social networks like Facebook, Twitter and Instagram, for example. There has been, in fact, a large number of pornographic content is distributed through these networks. However, this is not just about the flood of pornographic content in these media venues, but also on their structure, that the use of technical means, to the coincidence of public and intimate space of action in the area of private property. Text funds criticism tries to point out the specific problem of abuse of public space in contemporary times.

  19. National public health policy in a local context--implementation in two Swedish municipalities.

    Science.gov (United States)

    Jansson, Elisabeth; Fosse, Elisabeth; Tillgren, Per

    2011-12-01

    In 2003 the wide-ranging Swedish National Public Health Policy (SNPHP), with a focus on health determinants, was adopted by the Swedish parliament. In the context of multilevel governance, SNPHP implementation is dependent on self-governed municipalities and counties. The aim of the study is, from a municipal perspective, to investigate public-health policies in two municipalities. Content analysis of documents and interviews provided a foundation for an explorative case study. The SNPHP at national level is overriding but politically controversial. At local level, a health-determinants perspective was detectable in the policies implemented, but none regarding to health equality. At local level, the SNPHP is not regarded as implementable; rather, limited parts have, to varying degrees, been reconciled with local public-health goals, according to municipal needs and conditions. A success-promoting factor in the two municipalities was the presence of committed and knowledgeable actors/implementers. Also, the municipality with a more centrally controlled and stable party-political leadership succeeded better in implementing structural and intersectoral community-wide policies for coordinated local health promotion. The contents of national and local public-health policies differ, and municipalities that have implemented their own local health policies do not seem to regard the SNPHP as justifiable or adoptable. If the SNPHP overall aim regarding equal health is to be achieved homogeneously in Swedish municipalities, its contents and purpose need clearer management and negotiation, so that implementation of the national policy locally is understandable and motivated. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  20. International Public-private Partnership Policies

    DEFF Research Database (Denmark)

    Greve, Carsten

    This paper focuses on how international public-private partnership (PPP) policies are formulated and implemented by international organizations. PPPs for infrastructure projects are relevant and present in many countries around the world. The literature is full of studies of individual countries......, International Monetary Fund, OECD, UN, and the World Bank. The methodology is to examine the most recent policy papers (documents and reports) and compare their content and tools. The paper shows that international organizations cooperate on certain issues in policy Development and tools for PPPs. But each...