WorldWideScience

Sample records for public-domain databases research

  1. Molecular scaffold analysis of natural products databases in the public domain.

    Science.gov (United States)

    Yongye, Austin B; Waddell, Jacob; Medina-Franco, José L

    2012-11-01

    Natural products represent important sources of bioactive compounds in drug discovery efforts. In this work, we compiled five natural products databases available in the public domain and performed a comprehensive chemoinformatic analysis focused on the content and diversity of the scaffolds with an overview of the diversity based on molecular fingerprints. The natural products databases were compared with each other and with a set of molecules obtained from in-house combinatorial libraries, and with a general screening commercial library. It was found that publicly available natural products databases have different scaffold diversity. In contrast to the common concept that larger libraries have the largest scaffold diversity, the largest natural products collection analyzed in this work was not the most diverse. The general screening library showed, overall, the highest scaffold diversity. However, considering the most frequent scaffolds, the general reference library was the least diverse. In general, natural products databases in the public domain showed low molecule overlap. In addition to benzene and acyclic compounds, flavones, coumarins, and flavanones were identified as the most frequent molecular scaffolds across the different natural products collections. The results of this work have direct implications in the computational and experimental screening of natural product databases for drug discovery.

  2. The Use and Abuse of Research in the Public Domain

    Science.gov (United States)

    Reid, Alan

    2016-01-01

    In Australia, education think tanks have become increasingly influential in policy circles through "reports" to government, and in public debate through the mainstream media. Invariably think-tanks draw on educational research to lend authority and legitimacy to their work. This is desirable if the research deepens understandings about…

  3. Towards development of a high quality public domain global roads database

    Directory of Open Access Journals (Sweden)

    Andrew Nelson

    2006-12-01

    Full Text Available There is clear demand for a global spatial public domain roads data set with improved geographic and temporal coverage, consistent coding of road types, and clear documentation of sources. The currently best available global public domain product covers only one-quarter to one-third of the existing road networks, and this varies considerably by region. Applications for such a data set span multiple sectors and would be particularly valuable for the international economic development, disaster relief, and biodiversity conservation communities, not to mention national and regional agencies and organizations around the world. The building blocks for such a global product are available for many countries and regions, yet thus far there has been neither strategy nor leadership for developing it. This paper evaluates the best available public domain and commercial data sets, assesses the gaps in global coverage, and proposes a number of strategies for filling them. It also identifies stakeholder organizations with an interest in such a data set that might either provide leadership or funding for its development. It closes with a proposed set of actions to begin the process.

  4. Reclamation research database

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    A reclamation research database was compiled to help stakeholders search publications and research related to the reclamation of Alberta's oil sands region. New publications are added to the database by the Cumulative Environmental Management Association (CEMA), a nonprofit association whose mandate is to develop frameworks and guidelines for the management of cumulative environmental effects in the oil sands region. A total of 514 research papers have been compiled in the database to date. Topics include recent research on hydrology, aquatic and terrestrial ecosystems, laboratory studies on biodegradation, and the effects of oil sands processing on micro-organisms. The database includes a wide variety of studies related to reconstructed wetlands as well as the ecological effects of hydrocarbons on phytoplankton and other organisms. The database format included information on research format availability, as well as information related to the author's affiliations. Links to external abstracts were provided where available, as well as details of source information.

  5. Public Domain or Private Data? Developing an Ethical Approach to Social Media Research in an Inter-Disciplinary Project

    Science.gov (United States)

    Stevens, Gemma; O'Donnell, Victoria L.; Williams, Lynn

    2015-01-01

    This paper discusses the ethical issues faced in undertaking research about the role of learning in the subjective experience of chronic illness, where data were taken from social media. Drawing on psychology and education, this paper discusses the ways in which authors from these disciplines are laying the groundwork for legitimate online…

  6. Native Health Research Database

    Science.gov (United States)

    ... APP WITH JAVASCRIPT TURNED OFF. THE NATIVE HEALTH DATABASE REQUIRES JAVASCRIPT IN ORDER TO FUNCTION. PLEASE ENTER ... To learn more about searching the Native Health Database, click here. Keywords Title Author Source of Publication ...

  7. Surgical research using national databases.

    Science.gov (United States)

    Alluri, Ram K; Leland, Hyuma; Heckmann, Nathanael

    2016-10-01

    Recent changes in healthcare and advances in technology have increased the use of large-volume national databases in surgical research. These databases have been used to develop perioperative risk stratification tools, assess postoperative complications, calculate costs, and investigate numerous other topics across multiple surgical specialties. The results of these studies contain variable information but are subject to unique limitations. The use of large-volume national databases is increasing in popularity, and thorough understanding of these databases will allow for a more sophisticated and better educated interpretation of studies that utilize such databases. This review will highlight the composition, strengths, and weaknesses of commonly used national databases in surgical research.

  8. PUBLIC DOMAIN PROTECTION. USES AND REUSES OF PUBLIC DOMAIN WORKS

    OpenAIRE

    Monica Adriana LUPAȘCU

    2015-01-01

    This study tries to highlight the necessity of an awareness of the right of access to the public domain, particularly using the example of works whose protection period has expired, as well as the ones which the law considers to be excluded from protection. Such works are used not only by large libraries from around the world, but also by rights holders, via different means of use, including incorporations into original works or adaptations. However, the reuse that follows these uses often on...

  9. Database Research: Achievements and Challenges

    Institute of Scientific and Technical Information of China (English)

    Shan Wang; Xiao-Yong Du; Xiao-Feng Meng; Hong Chen

    2006-01-01

    Database system is the infrastructure of the modern information system. The R&D in the database system moves along by giant steps. This report presents the achievements Renmin University of China (RUC) has made in the past 25 years and at the same time addresses some of the research projects we, RUC, are currently working on. The National Natural Science Foundation of China supports and initiates most of our research projects and these successfully conducted projects have produced fruitful results.

  10. Biological Databases for Human Research

    Institute of Scientific and Technical Information of China (English)

    Dong Zou; Lina Ma; Jun Yu; Zhang Zhang

    2015-01-01

    The completion of the Human Genome Project lays a foundation for systematically studying the human genome from evolutionary history to precision medicine against diseases. With the explosive growth of biological data, there is an increasing number of biological databases that have been developed in aid of human-related research. Here we present a collection of human-related biological databases and provide a mini-review by classifying them into different categories according to their data types. As human-related databases continue to grow not only in count but also in volume, challenges are ahead in big data storage, processing, exchange and curation.

  11. Biological Databases for Human Research

    Science.gov (United States)

    Zou, Dong; Ma, Lina; Yu, Jun; Zhang, Zhang

    2015-01-01

    The completion of the Human Genome Project lays a foundation for systematically studying the human genome from evolutionary history to precision medicine against diseases. With the explosive growth of biological data, there is an increasing number of biological databases that have been developed in aid of human-related research. Here we present a collection of human-related biological databases and provide a mini-review by classifying them into different categories according to their data types. As human-related databases continue to grow not only in count but also in volume, challenges are ahead in big data storage, processing, exchange and curation. PMID:25712261

  12. Cultural Heritage and the Public Domain

    Directory of Open Access Journals (Sweden)

    Bas Savenije

    2012-09-01

    by providing their resources on the Internet” (Berlin Declaration 2003. Therefore, in the spirit of the Berlin Declaration, the ARL encourages its members’ libraries to grant all non-commercial users “a free, irrevocable, worldwide, right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship”. And: “If fees are to be assessed for the use of digitised public domain works, those fees should only apply to commercial uses” (ARL Principles July 2010. In our view, cultural heritage institutions should make public domain material digitised with public funding as widely available as possible for access and reuse. The public sector has the primary responsibility to fund digitisation. The involvement of private partners, however, is encouraged by ARL as well as the Comité des Sages. Private funding for digitisation is a complement to the necessary public investment, especially in times of economic crisis, but should not be seen as a substitute for public funding. As we can see from these reports there are a number of arguments in favour of digitisation and also of providing maximum accessibility to the digitised cultural heritage. In this paper we will investigate the legal aspects of digitisation of cultural heritage, especially public domain material. On the basis of these we will make an inventory of policy considerations regarding reuse. Furthermore, we will describe the conclusions the National Library of the Netherlands (hereafter: KB has formulated and the arguments that support these. In this context we will review public-private partnerships and also the policy of the KB. We will conclude with recommendations for cultural heritage institutions concerning a reuse policy for digitised public domain material.

  13. Copyright and the Value of the Public Domain

    OpenAIRE

    Erickson, Kristofer; Heald, Paul; Homberg, Fabian; Kretschmer, Martin; Mendis, Dinusha

    2015-01-01

    This research report documents the results of a year-long knowledge exchange initiative undertaken between the Intellectual Property Office, researchers at the University of Glasgow CREATe Centre, and more than two dozen UK businesses and innovators, to explore how value is generated from the public domain. The study was supported by the Economic and Social Research Council (ESRC) and the Intellectual Property Office (IPO). The core research team consisted of Dr. Kristofer Erickson (Lord Kelv...

  14. USDA food and nutrient databases provide the infrastructure for food and nutrition research, policy, and practice.

    Science.gov (United States)

    Ahuja, Jaspreet K C; Moshfegh, Alanna J; Holden, Joanne M; Harris, Ellen

    2013-02-01

    The USDA food and nutrient databases provide the basic infrastructure for food and nutrition research, nutrition monitoring, policy, and dietary practice. They have had a long history that goes back to 1892 and are unique, as they are the only databases available in the public domain that perform these functions. There are 4 major food and nutrient databases released by the Beltsville Human Nutrition Research Center (BHNRC), part of the USDA's Agricultural Research Service. These include the USDA National Nutrient Database for Standard Reference, the Dietary Supplement Ingredient Database, the Food and Nutrient Database for Dietary Studies, and the USDA Food Patterns Equivalents Database. The users of the databases are diverse and include federal agencies, the food industry, health professionals, restaurants, software application developers, academia and research organizations, international organizations, and foreign governments, among others. Many of these users have partnered with BHNRC to leverage funds and/or scientific expertise to work toward common goals. The use of the databases has increased tremendously in the past few years, especially the breadth of uses. These new uses of the data are bound to increase with the increased availability of technology and public health emphasis on diet-related measures such as sodium and energy reduction. Hence, continued improvement of the databases is important, so that they can better address these challenges and provide reliable and accurate data.

  15. Fundamental Research of Distributed Database

    Directory of Open Access Journals (Sweden)

    Swati Gupta

    2011-08-01

    Full Text Available The purpose of this paper is to present an introduction toDistributed Databases which are becoming very popularnow a days. Today’s business environment has anincreasing need for distributed database and Client/server applications as the desire for reliable, scalable and accessible information is Steadily rising. Distributed database systems provide an improvement on communication and data processing due to its datadistribution throughout different network sites. Not Only isdata access faster, but a single-point of failure is less likelyto occur, and it provides local control of data for users.

  16. A Decade of Database Research Publications

    CERN Document Server

    Sakr, Sherif

    2011-01-01

    We analyze the database research publications of four major core database technology conferences (SIGMOD, VLDB, ICDE, EDBT), two main theoretical database conferences (PODS, ICDT) and three database journals (TODS, VLDB Journal, TKDE) over a period of 10 years (2001 - 2010). Our analysis considers only regular papers as we do not include short papers, demo papers, posters, tutorials or panels into our statistics. We rank the research scholars according to their number of publication in each conference/journal separately and in combined. We also report about the growth in the number of research publications and the size of the research community in the last decade.

  17. Correlates of Access to Business Research Databases

    Science.gov (United States)

    Gottfried, John C.

    2010-01-01

    This study examines potential correlates of business research database access through academic libraries serving top business programs in the United States. Results indicate that greater access to research databases is related to enrollment in graduate business programs, but not to overall enrollment or status as a public or private institution.…

  18. Database Support for Research in Public Administration

    Science.gov (United States)

    Tucker, James Cory

    2005-01-01

    This study examines the extent to which databases support student and faculty research in the area of public administration. A list of journals in public administration, public policy, political science, public budgeting and finance, and other related areas was compared to the journal content list of six business databases. These databases…

  19. National Database for Autism Research (NDAR)

    Data.gov (United States)

    U.S. Department of Health & Human Services — National Database for Autism Research (NDAR) is an extensible, scalable informatics platform for austism spectrum disorder-relevant data at all levels of biological...

  20. Research on computer virus database management system

    Science.gov (United States)

    Qi, Guoquan

    2011-12-01

    The growing proliferation of computer viruses becomes the lethal threat and research focus of the security of network information. While new virus is emerging, the number of viruses is growing, virus classification increasing complex. Virus naming because of agencies' capture time differences can not be unified. Although each agency has its own virus database, the communication between each other lacks, or virus information is incomplete, or a small number of sample information. This paper introduces the current construction status of the virus database at home and abroad, analyzes how to standardize and complete description of virus characteristics, and then gives the information integrity, storage security and manageable computer virus database design scheme.

  1. Emerging multidisciplinary research across database management systems

    CERN Document Server

    Nica, Anisoara; Varde, Aparna

    2011-01-01

    The database community is exploring more and more multidisciplinary avenues: Data semantics overlaps with ontology management; reasoning tasks venture into the domain of artificial intelligence; and data stream management and information retrieval shake hands, e.g., when processing Web click-streams. These new research avenues become evident, for example, in the topics that doctoral students choose for their dissertations. This paper surveys the emerging multidisciplinary research by doctoral students in database systems and related areas. It is based on the PIKM 2010, which is the 3rd Ph.D. workshop at the International Conference on Information and Knowledge Management (CIKM). The topics addressed include ontology development, data streams, natural language processing, medical databases, green energy, cloud computing, and exploratory search. In addition to core ideas from the workshop, we list some open research questions in these multidisciplinary areas.

  2. An online database for brain disease research

    Directory of Open Access Journals (Sweden)

    Richman Sam

    2006-04-01

    Full Text Available Abstract Background The Stanley Medical Research Institute online genomics database (SMRIDB is a comprehensive web-based system for understanding the genetic effects of human brain disease (i.e. bipolar, schizophrenia, and depression. This database contains fully annotated clinical metadata and gene expression patterns generated within 12 controlled studies across 6 different microarray platforms. Description A thorough collection of gene expression summaries are provided, inclusive of patient demographics, disease subclasses, regulated biological pathways, and functional classifications. Conclusion The combination of database content, structure, and query speed offers researchers an efficient tool for data mining of brain disease complete with information such as: cross-platform comparisons, biomarkers elucidation for target discovery, and lifestyle/demographic associations to brain diseases.

  3. Preserving the positive functions of the public domain in science

    Directory of Open Access Journals (Sweden)

    Pamela Samuelson

    2003-11-01

    Full Text Available Science has advanced in part because data and scientific methodologies have traditionally not been subject to intellectual property protection. In recent years, intellectual property has played a greater role in scientific work. While intellectual property rights may have a positive role to play in some fields of science, so does the public domain. This paper will discuss some of the positive functions of the public domain and ways in which certain legal developments may negatively impact the public domain. It suggests some steps that scientists can take to preserve the positive functions of the public domain for science.

  4. EnArgus – Federal Research Database on Energy Research

    OpenAIRE

    Wirth, Hans-Christoph

    2013-01-01

    27 slides.-- Presentation delivered at the German National Session (Section II) The presentation introduces the German Database on Energy Research that is to provide the required research information to assess the impact of the 6th Energy Research Programme implemented by the Federal Ministry for Economy and Technology -- including research funding, projects and outputs.

  5. Multicenter neonatal databases: Trends in research uses.

    Science.gov (United States)

    Creel, Liza M; Gregory, Sean; McNeal, Catherine J; Beeram, Madhava R; Krauss, David R

    2017-01-13

    In the US, approximately 12.7% of all live births are preterm, 8.2% of live births were low birth weight (LBW), and 1.5% are very low birth weight (VLBW). Although technological advances have improved mortality rates among preterm and LBW infants, improving overall rates of prematurity and LBW remains a national priority. Monitoring short- and long-term outcomes is critical for advancing medical treatment and minimizing morbidities associated with prematurity or LBW; however, studying these infants can be challenging. Several large, multi-center neonatal databases have been developed to improve research and quality improvement of treatments for and outcomes of premature and LBW infants. The purpose of this systematic review was to describe three multi-center neonatal databases. We conducted a literature search using PubMed and Google Scholar over the period 1990 to August 2014. Studies were included in our review if one of the databases was used as a primary source of data or comparison. Included studies were categorized by year of publication; study design employed, and research focus. A total of 343 studies published between 1991 and 2014 were included. Studies of premature and LBW infants using these databases have increased over time, and provide evidence for both neonatology and community-based pediatric practice. Research into treatment and outcomes of premature and LBW infants is expanding, partially due to the availability of large, multicenter databases. The consistency of clinical conditions and neonatal outcomes studied since 1990 demonstrates that there are dedicated research agendas and resources that allow for long-term, and potentially replicable, studies within this population.

  6. Nucleic Acids Research annual Database Issue and the NAR online Molecular Biology Database Collection in 2009.

    Science.gov (United States)

    Galperin, Michael Y; Cochrane, Guy R

    2009-01-01

    The current issue of Nucleic Acids Research includes descriptions of 179 databases, of which 95 are new. These databases (along with several molecular biology databases described in other journals) have been included in the Nucleic Acids Research online Molecular Biology Database Collection, bringing the total number of databases in the collection to 1170. In this introductory comment, we briefly describe some of these new databases and review the principles guiding the selection of databases for inclusion in the Nucleic Acids Research annual Database Issue and the Nucleic Acids Research online Molecular Biology Database Collection. The complete database list and summaries are available online at the Nucleic Acids Research web site (http://nar.oxfordjournals.org/).

  7. 22 CFR 120.11 - Public domain.

    Science.gov (United States)

    2010-04-01

    .... Government and specific access and dissemination controls protecting information resulting from the research... published information; (3) Through second class mailing privileges granted by the U.S. Government; (4) At.... Government access and dissemination controls. University research will not be considered fundamental...

  8. The 2013 Nucleic Acids Research Database Issue and the online molecular biology database collection.

    Science.gov (United States)

    Fernández-Suárez, Xosé M; Galperin, Michael Y

    2013-01-01

    The 20th annual Database Issue of Nucleic Acids Research includes 176 articles, half of which describe new online molecular biology databases and the other half provide updates on the databases previously featured in NAR and other journals. This year's highlights include two databases of DNA repeat elements; several databases of transcriptional factors and transcriptional factor-binding sites; databases on various aspects of protein structure and protein-protein interactions; databases for metagenomic and rRNA sequence analysis; and four databases specifically dedicated to Escherichia coli. The increased emphasis on using the genome data to improve human health is reflected in the development of the databases of genomic structural variation (NCBI's dbVar and EBI's DGVa), the NIH Genetic Testing Registry and several other databases centered on the genetic basis of human disease, potential drugs, their targets and the mechanisms of protein-ligand binding. Two new databases present genomic and RNAseq data for monkeys, providing wealth of data on our closest relatives for comparative genomics purposes. The NAR online Molecular Biology Database Collection, available at http://www.oxfordjournals.org/nar/database/a/, has been updated and currently lists 1512 online databases. The full content of the Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/).

  9. Security Research on Engineering Database System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Engine engineering database system is an oriented C AD applied database management system that has the capability managing distributed data. The paper discusses the security issue of the engine engineering database management system (EDBMS). Through studying and analyzing the database security, to draw a series of securi ty rules, which reach B1, level security standard. Which includes discretionary access control (DAC), mandatory access control (MAC) and audit. The EDBMS implem ents functions of DAC, ...

  10. The 2012 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection.

    Science.gov (United States)

    Galperin, Michael Y; Fernández-Suárez, Xosé M

    2012-01-01

    The 19th annual Database Issue of Nucleic Acids Research features descriptions of 92 new online databases covering various areas of molecular biology and 100 papers describing recent updates to the databases previously described in NAR and other journals. The highlights of this issue include, among others, a description of neXtProt, a knowledgebase on human proteins; a detailed explanation of the principles behind the NCBI Taxonomy Database; NCBI and EBI papers on the recently launched BioSample databases that store sample information for a variety of database resources; descriptions of the recent developments in the Gene Ontology and UniProt Gene Ontology Annotation projects; updates on Pfam, SMART and InterPro domain databases; update papers on KEGG and TAIR, two universally acclaimed databases that face an uncertain future; and a separate section with 10 wiki-based databases, introduced in an accompanying editorial. The NAR online Molecular Biology Database Collection, available at http://www.oxfordjournals.org/nar/database/a/, has been updated and now lists 1380 databases. Brief machine-readable descriptions of the databases featured in this issue, according to the BioDBcore standards, will be provided at the http://biosharing.org/biodbcore web site. The full content of the Database Issue is freely available online on the Nucleic Acids Research web site (http://nar.oxfordjournals.org/).

  11. The 2010 Nucleic Acids Research Database Issue and online Database Collection: a community of data resources.

    Science.gov (United States)

    Cochrane, Guy R; Galperin, Michael Y

    2010-01-01

    The current issue of Nucleic Acids Research includes descriptions of 58 new and 73 updated data resources. The accompanying online Database Collection, available at http://www.oxfordjournals.org/nar/database/a/, now lists 1230 carefully selected databases covering various aspects of molecular and cell biology. While most data resource descriptions remain very brief, the issue includes several longer papers that highlight recent significant developments in such databases as Pfam, MetaCyc, UniProt, ELM and PDBe. The databases described in the Database Issue and Database Collection, however, are far more than a distinct set of resources; they form a network of connected data, concepts and shared technology. The full content of the Database Issue is available online at the Nucleic Acids Research web site (http://nar.oxfordjournals.org/).

  12. Database tools in genetic diseases research.

    Science.gov (United States)

    Bianco, Anna Monica; Marcuzzi, Annalisa; Zanin, Valentina; Girardelli, Martina; Vuch, Josef; Crovella, Sergio

    2013-02-01

    The knowledge of the human genome is in continuous progression: a large number of databases have been developed to make meaningful connections among worldwide scientific discoveries. This paper reviews bioinformatics resources and database tools specialized in disseminating information regarding genetic disorders. The databases described are useful for managing sample sequences, gene expression and post-transcriptional regulation. In relation to data sets available from genome-wide association studies, we describe databases that could be the starting point for developing studies in the field of complex diseases, particularly those in which the causal genes are difficult to identify.

  13. RIDE: the Research Infrastructure Database for EPOS

    Science.gov (United States)

    Bailo, Daniele; Bartoloni, Alessandro; Jeffery, Keith G.; Clemenceau, Alice; Hoffmann, Thomas L.

    2013-04-01

    The European Plate Observing System (EPOS) is a European initiative which aims to promote and make possible innovative approaches for a better understanding of the physical processes laying behind natural events and geo-science phenomena (earthquakes, volcanic eruptions, unrest episodes and tsunamis etc.) by integrating existing national and trans-national Research Infrastructures (RIs). Such integration will increase access and use of the multidisciplinary data recorded by solid Earth monitoring networks, acquired in laboratory experiments and/or produced by computational simulations. Here we present the Research Infrastructures Database for EPOS (RIDE), a database containing technical information about the different RIs declared by EPOS partners and EPOS associate partners, which will eventually compose the EPOS distributed Research Infrastructure. The main goals of RIDE are (i) to allow the EPOS RI to be organized, with interactive access and information mining available to a broad community of users and stakeholders, (ii) to have a first set of information to be stored in the EPOS catalogue, which will be used as a basis for the development of EPOS Core Services, (iii) to enable EPOS partners to revise and update the current RI information, (iv) to show the contents of the EPOS integration plan to all stakeholders, (v) to facilitate the dissemination of existing data infrastructures to different communities and to promote a discussion within the community to implement the present data infrastructures. RIDE - whose driving technology is Apache CouchDB - contains at the current status detailed information on more than 200 Research Infrastructures. It enables any user to visualize RIs and sensors on a map, to carry out statistics on the stored data and to browse through the details of any RI. Based on the content of RIDE it is now possible to estimate the potential size of the new EPOS distributed RI: EPOS is going to integrate more than 7000 sensors (seismic

  14. The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection.

    Science.gov (United States)

    Galperin, Michael Y; Cochrane, Guy R

    2011-01-01

    The current 18th Database Issue of Nucleic Acids Research features descriptions of 96 new and 83 updated online databases covering various areas of molecular biology. It includes two editorials, one that discusses COMBREX, a new exciting project aimed at figuring out the functions of the 'conserved hypothetical' proteins, and one concerning BioDBcore, a proposed description of the 'minimal information about a biological database'. Papers from the members of the International Nucleotide Sequence Database collaboration (INSDC) describe each of the participating databases, DDBJ, ENA and GenBank, principles of data exchange within the collaboration, and the recently established Sequence Read Archive. A testament to the longevity of databases, this issue includes updates on the RNA modification database, Definition of Secondary Structure of Proteins (DSSP) and Homology-derived Secondary Structure of Proteins (HSSP) databases, which have not been featured here in >12 years. There is also a block of papers describing recent progress in protein structure databases, such as Protein DataBank (PDB), PDB in Europe (PDBe), CATH, SUPERFAMILY and others, as well as databases on protein structure modeling, protein-protein interactions and the organization of inter-protein contact sites. Other highlights include updates of the popular gene expression databases, GEO and ArrayExpress, several cancer gene databases and a detailed description of the UK PubMed Central project. The Nucleic Acids Research online Database Collection, available at: http://www.oxfordjournals.org/nar/database/a/, now lists 1330 carefully selected molecular biology databases. The full content of the Database Issue is freely available online at the Nucleic Acids Research web site (http://nar.oxfordjournals.org/).

  15. Hypertext and Database Tools for Qualitative Research.

    Science.gov (United States)

    Horney, Mark A.; Healey, Deborah

    This study compared and contrasted the use of hypertext and relational database knowledge representation techniques in the analysis of qualitative data. A parallel analysis of teacher interview transcripts was conducted with two computer programs: "EntryWay," a hypertext editor, and "FoxBase+/Mac," a relational database with a…

  16. The 2015 Nucleic Acids Research Database Issue and molecular biology database collection.

    Science.gov (United States)

    Galperin, Michael Y; Rigden, Daniel J; Fernández-Suárez, Xosé M

    2015-01-01

    The 2015 Nucleic Acids Research Database Issue contains 172 papers that include descriptions of 56 new molecular biology databases, and updates on 115 databases whose descriptions have been previously published in NAR or other journals. Following the classification that has been introduced last year in order to simplify navigation of the entire issue, these articles are divided into eight subject categories. This year's highlights include RNAcentral, an international community portal to various databases on noncoding RNA; ValidatorDB, a validation database for protein structures and their ligands; SASBDB, a primary repository for small-angle scattering data of various macromolecular complexes; MoonProt, a database of 'moonlighting' proteins, and two new databases of protein-protein and other macromolecular complexes, ComPPI and the Complex Portal. This issue also includes an unusually high number of cancer-related databases and other databases dedicated to genomic basics of disease and potential drugs and drug targets. The size of NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/a/, remained approximately the same, following the addition of 74 new resources and removal of 77 obsolete web sites. The entire Database Issue is freely available online on the Nucleic Acids Research web site (http://nar.oxfordjournals.org/).

  17. The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection.

    Science.gov (United States)

    Fernández-Suárez, Xosé M; Rigden, Daniel J; Galperin, Michael Y

    2014-01-01

    The 2014 Nucleic Acids Research Database Issue includes descriptions of 58 new molecular biology databases and recent updates to 123 databases previously featured in NAR or other journals. For convenience, the issue is now divided into eight sections that reflect major subject categories. Among the highlights of this issue are six databases of the transcription factor binding sites in various organisms and updates on such popular databases as CAZy, Database of Genomic Variants (DGV), dbGaP, DrugBank, KEGG, miRBase, Pfam, Reactome, SEED, TCDB and UniProt. There is a strong block of structural databases, which includes, among others, the new RNA Bricks database, updates on PDBe, PDBsum, ArchDB, Gene3D, ModBase, Nucleic Acid Database and the recently revived iPfam database. An update on the NCBI's MMDB describes VAST+, an improved tool for protein structure comparison. Two articles highlight the development of the Structural Classification of Proteins (SCOP) database: one describes SCOPe, which automates assignment of new structures to the existing SCOP hierarchy; the other one describes the first version of SCOP2, with its more flexible approach to classifying protein structures. This issue also includes a collection of articles on bacterial taxonomy and metagenomics, which includes updates on the List of Prokaryotic Names with Standing in Nomenclature (LPSN), Ribosomal Database Project (RDP), the Silva/LTP project and several new metagenomics resources. The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been expanded to 1552 databases. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/).

  18. The Human Communication Research Centre dialogue database.

    Science.gov (United States)

    Anderson, A H; Garrod, S C; Clark, A; Boyle, E; Mullin, J

    1992-10-01

    The HCRC dialogue database consists of over 700 transcribed and coded dialogues from pairs of speakers aged from seven to fourteen. The speakers are recorded while tackling co-operative problem-solving tasks and the same pairs of speakers are recorded over two years tackling 10 different versions of our two tasks. In addition there are over 200 dialogues recorded between pairs of undergraduate speakers engaged on versions of the same tasks. Access to the database, and to its accompanying custom-built search software, is available electronically over the JANET system by contacting liz@psy.glasgow.ac.uk, from whom further information about the database and a user's guide to the database can be obtained.

  19. Development and Initial Validation of Public Domain Basic Interest Markers

    Science.gov (United States)

    Liao, Hsin-Ya; Armstrong, Patrick Ian; Rounds, James

    2008-01-01

    Goldberg (Goldberg, L. R. (1999). "A broad-bandwidth, public-domain, personality inventory measuring the lower-level facets of several five-factor models." In: I. Mervielde, I. Deary, F. De Fruyt, & F. Ostendorf (Eds.), "Personality psychology in Europe" (Vol. 7, pp. 7-28). Tilburg, The Netherlands: Tilburg University Press) has argued that the…

  20. Research Directions in Database Security IV

    Science.gov (United States)

    1993-07-01

    second algorithm, which is based on multiversion timestamp ordering, is that high level transactions can be forced to read arbitrarily old data values...system. The first, the single ver- sion model, stores only the latest veision of each data item, while the second, the 88 multiversion model, stores... Multiversion Database Model In the standard database model, where there is only one version of each data item, all transactions compete for the most recent

  1. Databases and registers: useful tools for research, no studies.

    Science.gov (United States)

    Curbelo, Rafael J; Loza, Estíbaliz; de Yébenes, Maria Jesús García; Carmona, Loreto

    2014-04-01

    There are many misunderstandings about databases. Database is a commonly misused term in reference to any set of data entered into a computer. However, true databases serve a main purpose, organising data. They do so by establishing several layers of relationships; databases are hierarchical. Databases commonly organise data over different levels and over time, where time can be measured as the time between visits, or between treatments, or adverse events, etc. In this sense, medical databases are closely related to longitudinal observational studies, as databases allow the introduction of data on the same patient over time. Basically, we could establish four types of databases in medicine, depending on their purpose: (1) administrative databases, (2) clinical databases, (3) registers, and (4) study-oriented databases. But a database is a useful tool for a large variety of studies, not a type of study itself. Different types of databases serve very different purposes, and a clear understanding of the different research designs mentioned in this paper would prevent many of the databases we launch from being just a lot of work and very little science.

  2. The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection.

    Science.gov (United States)

    Rigden, Daniel J; Fernández-Suárez, Xosé M; Galperin, Michael Y

    2016-01-04

    The 2016 Database Issue of Nucleic Acids Research starts with overviews of the resources provided by three major bioinformatics centers, the U.S. National Center for Biotechnology Information (NCBI), the European Bioinformatics Institute (EMBL-EBI) and Swiss Institute for Bioinformatics (SIB). Also included are descriptions of 62 new databases and updates on 95 databases that have been previously featured in NAR plus 17 previously described elsewhere. A number of papers in this issue deal with resources on nucleic acids, including various kinds of non-coding RNAs and their interactions, molecular dynamics simulations of nucleic acid structure, and two databases of super-enhancers. The protein database section features important updates on the EBI's Pfam, PDBe and PRIDE databases, as well as a variety of resources on pathways, metabolomics and metabolic modeling. This issue also includes updates on popular metagenomics resources, such as MG-RAST, EBI Metagenomics, and probeBASE, as well as a newly compiled Human Pan-Microbe Communities database. A significant fraction of the new and updated databases are dedicated to the genetic basis of disease, primarily cancer, and various aspects of drug research, including resources for patented drugs, their side effects, withdrawn drugs, and potential drug targets. A further six papers present updated databases of various antimicrobial and anticancer peptides. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/). The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been updated with the addition of 88 new resources and removal of 23 obsolete websites, which brought the current listing to 1685 databases.

  3. Use of administrative medical databases in population-based research.

    Science.gov (United States)

    Gavrielov-Yusim, Natalie; Friger, Michael

    2014-03-01

    Administrative medical databases are massive repositories of data collected in healthcare for various purposes. Such databases are maintained in hospitals, health maintenance organisations and health insurance organisations. Administrative databases may contain medical claims for reimbursement, records of health services, medical procedures, prescriptions, and diagnoses information. It is clear that such systems may provide a valuable variety of clinical and demographic information as well as an on-going process of data collection. In general, information gathering in these databases does not initially presume and is not planned for research purposes. Nonetheless, administrative databases may be used as a robust research tool. In this article, we address the subject of public health research that employs administrative data. We discuss the biases and the limitations of such research, as well as other important epidemiological and biostatistical key points specific to administrative database studies.

  4. Databases and their application

    NARCIS (Netherlands)

    E.C. Grimm; R.H.W Bradshaw; S. Brewer; S. Flantua; T. Giesecke; A.M. Lézine; H. Takahara; J.W.,Jr Williams

    2013-01-01

    During the past 20 years, several pollen database cooperatives have been established. These databases are now constituent databases of the Neotoma Paleoecology Database, a public domain, multiproxy, relational database designed for Quaternary-Pliocene fossil data and modern surface samples. The poll

  5. Databases in the 3rd Millennium: Trends and Research Directions

    Directory of Open Access Journals (Sweden)

    Jaroslav Pokorny

    2010-04-01

    Full Text Available A database approach to data of arbitrary types has shown that the architecture of a universal database machine is restricting in a number of cases. There appear special-purpose data servers using now types of hardware devices. Data is moving toward the user, who exploits mobile devices equipped with database functionality. The goal of the paper is to present new trends in databases, particularly in their architectures and to show on cloud computing, data streams, mobile and embedded databases, and databases supporting Web.2.0 some new ideas and possibilities of solution of associated problems. The other goal of the paper is also to point out on actual problems associated with database research.

  6. The European Project and Literature Database for Organic Farming Research

    OpenAIRE

    Willer, Helga

    2003-01-01

    Currently an internet- based platform for organic farming research in Germany and Europe is established as part of the German internet portal for organic farming. This portal is financed by the German Ministry of Consumer Protection, Food And Agriculture within the federal scheme for organic agriculture. An important part of the research platform is a database, containing all relevant results and projects. This database was developed by the Danish Research Centre for Organic Agriculture (DARC...

  7. The Vocational Guidance Research Database: A Scientometric Approach

    Science.gov (United States)

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the use of…

  8. The Vocational Guidance Research Database: A Scientometric Approach

    Science.gov (United States)

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the…

  9. The Vocational Guidance Research Database: A Scientometric Approach

    Science.gov (United States)

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the…

  10. National Databases for Neurosurgical Outcomes Research: Options, Strengths, and Limitations.

    Science.gov (United States)

    Karhade, Aditya V; Larsen, Alexandra M G; Cote, David J; Dubois, Heloise M; Smith, Timothy R

    2017-08-05

    Quality improvement, value-based care delivery, and personalized patient care depend on robust clinical, financial, and demographic data streams of neurosurgical outcomes. The neurosurgical literature lacks a comprehensive review of large national databases. To assess the strengths and limitations of various resources for outcomes research in neurosurgery. A review of the literature was conducted to identify surgical outcomes studies using national data sets. The databases were assessed for the availability of patient demographics and clinical variables, longitudinal follow-up of patients, strengths, and limitations. The number of unique patients contained within each data set ranged from thousands (Quality Outcomes Database [QOD]) to hundreds of millions (MarketScan). Databases with both clinical and financial data included PearlDiver, Premier Healthcare Database, Vizient Clinical Data Base and Resource Manager, and the National Inpatient Sample. Outcomes collected by databases included patient-reported outcomes (QOD); 30-day morbidity, readmissions, and reoperations (National Surgical Quality Improvement Program); and disease incidence and disease-specific survival (Surveillance, Epidemiology, and End Results-Medicare). The strengths of large databases included large numbers of rare pathologies and multi-institutional nationally representative sampling; the limitations of these databases included variable data veracity, variable data completeness, and missing disease-specific variables. The improvement of existing large national databases and the establishment of new registries will be crucial to the future of neurosurgical outcomes research.

  11. Research on methods of designing and building digital seabed database

    Institute of Scientific and Technical Information of China (English)

    Su Tianyun; Liu Baohua; Zhai Shikui; Liang Ruicai; Zheng Yanpeng; Fu Qiang

    2007-01-01

    With a review of the recent development in digitalization and application of seabed data , this paper systematically proposed methods for integrating seabed data by analyzing its feature based on ORACLE database management system and advanced techniques of spatial data management. We did research on storage structure of seabed data, distributed- integrated database system, standardized spatial database and seabed metadata management system in order to effectively manage and use these seabed information in practical application . Finally , we applied the methods researched and proposed in this paper to build the Bohai Sea engineering geology database that stores engineering geology data and other seabed information from the Bohai Sea area . As a result , the Bohai Sea engineering geology database can effectively integrate huge amount of distributed and complicated seabed data to meet the practical requisition of Bohai Sea engineering geology environment exploration and exploitation.

  12. Quality of Researchers' Searches of the ERIC Database

    Directory of Open Access Journals (Sweden)

    Scott Hertzberg

    1999-08-01

    Full Text Available During the last ten years, end-users of electronic databases have become progressively less dependent on librarians and other intermediaries. This is certainly the case with the Educational Resources Information Center (ERIC Database, a resource once accessed by passing a paper query form to a librarian and now increasingly searched directly by end-users. This article empirically examines the search strategies currently being used by researchers and other groups. College professors and educational researchers appear to be doing a better job searching the database than other ERIC patrons. However, the study suggests that most end-users should be using much better search strategies.

  13. Agents unleashed a public domain look at agent technology

    CERN Document Server

    Wayner, Peter

    1995-01-01

    Agents Unleashed: A Public Domain Look at Agent Technology covers details of building a secure agent realm. The book discusses the technology for creating seamlessly integrated networks that allow programs to move from machine to machine without leaving a trail of havoc; as well as the technical details of how an agent will move through the network, prove its identity, and execute its code without endangering the host. The text also describes the organization of the host's work processing an agent; error messages, bad agent expulsion, and errors in XLISP-agents; and the simulators of errors, f

  14. Databases for multilevel biophysiology research available at Physiome.jp.

    Science.gov (United States)

    Asai, Yoshiyuki; Abe, Takeshi; Li, Li; Oka, Hideki; Nomura, Taishin; Kitano, Hiroaki

    2015-01-01

    Physiome.jp (http://physiome.jp) is a portal site inaugurated in 2007 to support model-based research in physiome and systems biology. At Physiome.jp, several tools and databases are available to support construction of physiological, multi-hierarchical, large-scale models. There are three databases in Physiome.jp, housing mathematical models, morphological data, and time-series data. In late 2013, the site was fully renovated, and in May 2015, new functions were implemented to provide information infrastructure to support collaborative activities for developing models and performing simulations within the database framework. This article describes updates to the databases implemented since 2013, including cooperation among the three databases, interactive model browsing, user management, version management of models, management of parameter sets, and interoperability with applications.

  15. A Philosophy Research Database to Share Data Resources

    Directory of Open Access Journals (Sweden)

    Jili Cheng

    2007-12-01

    Full Text Available Philosophy research used to rely mainly on the traditional published journals and newspapers for collecting or communicating data. However, because of financial limits or lack of capability to collect data, required published materials and even restricted materials and developing information from research projects often could not be obtained. The rise of digital techniques and Internet opportunities has allowed data resource sharing of philosophy research. However, although there are several ICPs with large-scale comprehensive commercial databases in the field in China, no real non-profit professional database for philosophy researchers exists. Therefore, in 2002, the Philosophy Institute of the Chinese Academy of Social Sciences began a project to build "The Database of Philosophy Research." Until Mar. 2006 the number of subsets had reached 30, with more than 30,000 records, retrieval services reached 6,000, and article-reading reached 30,000. Because of the concept of intellectual property, the service of the database is currently limited to the information held in CASS. Nevertheless, this is the first academic database for philosophy research, so its orientation is towards resource-sharing, leading users to data, and serving large number of demands from other provinces and departments.

  16. NIST Gas Hydrate Research Database and Web Dissemination Channel.

    Science.gov (United States)

    Kroenlein, K; Muzny, C D; Kazakov, A; Diky, V V; Chirico, R D; Frenkel, M; Sloan, E D

    2010-01-01

    To facilitate advances in application of technologies pertaining to gas hydrates, a freely available data resource containing experimentally derived information about those materials was developed. This work was performed by the Thermodynamic Research Center (TRC) paralleling a highly successful database of thermodynamic and transport properties of molecular pure compounds and their mixtures. Population of the gas-hydrates database required development of guided data capture (GDC) software designed to convert experimental data and metadata into a well organized electronic format, as well as a relational database schema to accommodate all types of numerical and metadata within the scope of the project. To guarantee utility for the broad gas hydrate research community, TRC worked closely with the Committee on Data for Science and Technology (CODATA) task group for Data on Natural Gas Hydrates, an international data sharing effort, in developing a gas hydrate markup language (GHML). The fruits of these efforts are disseminated through the NIST Sandard Reference Data Program [1] as the Clathrate Hydrate Physical Property Database (SRD #156). A web-based interface for this database, as well as scientific results from the Mallik 2002 Gas Hydrate Production Research Well Program [2], is deployed at http://gashydrates.nist.gov.

  17. Open access high throughput drug discovery in the public domain: a Mount Everest in the making.

    Science.gov (United States)

    Roy, Anuradha; McDonald, Peter R; Sittampalam, Sitta; Chaguturu, Rathnam

    2010-11-01

    High throughput screening (HTS) facilitates screening large numbers of compounds against a biochemical target of interest using validated biological or biophysical assays. In recent years, a significant number of drugs in clinical trails originated from HTS campaigns, validating HTS as a bona fide mechanism for hit finding. In the current drug discovery landscape, the pharmaceutical industry is embracing open innovation strategies with academia to maximize their research capabilities and to feed their drug discovery pipeline. The goals of academic research have therefore expanded from target identification and validation to probe discovery, chemical genomics, and compound library screening. This trend is reflected in the emergence of HTS centers in the public domain over the past decade, ranging in size from modestly equipped academic screening centers to well endowed Molecular Libraries Probe Centers Network (MLPCN) centers funded by the NIH Roadmap initiative. These centers facilitate a comprehensive approach to probe discovery in academia and utilize both classical and cutting-edge assay technologies for executing primary and secondary screening campaigns. The various facets of academic HTS centers as well as their implications on technology transfer and drug discovery are discussed, and a roadmap for successful drug discovery in the public domain is presented. New lead discovery against therapeutic targets, especially those involving the rare and neglected diseases, is indeed a Mount Everestonian size task, and requires diligent implementation of pharmaceutical industry's best practices for a successful outcome.

  18. Norwegian words: A lexical database for clinicians and researchers.

    Science.gov (United States)

    Lind, Marianne; Simonsen, Hanne Gram; Hansen, Pernille; Holm, Elisabeth; Mevik, Bjørn-Helge

    2015-04-01

    All words have properties linked to form, meaning and usage patterns which influence how easily they are accessed from the mental lexicon in language production, perception and comprehension. Examples of such properties are imageability, phonological and morphological complexity, word class, argument structure, frequency of use and age of acquisition. Due to linguistic and cultural variation the properties and the values associated with them differ across languages. Hence, for research as well as clinical purposes, language specific information on lexical properties is needed. To meet this need, an electronically searchable lexical database with more than 1600 Norwegian words coded for more than 12 different properties has been established. This article presents the content and structure of the database as well as the search options available in the interface. Finally, it briefly describes some of the ways in which the database can be used in research, clinical practice and teaching.

  19. A lexical database tool for quantitative phonological research

    CERN Document Server

    Bird, S D

    1999-01-01

    A lexical database tool tailored for phonological research is described. Database fields include transcriptions, glosses and hyperlinks to speech files. Database queries are expressed using HTML forms, and these permit regular expression search on any combination of fields. Regular expressions are passed directly to a Perl CGI program, enabling the full flexibility of Perl extended regular expressions. The regular expression notation is extended to better support phonological searches, such as search for minimal pairs. Search results are presented in the form of HTML or LaTeX tables, where each cell is either a number (representing frequency) or a designated subset of the fields. Tables have up to four dimensions, with an elegant system for specifying which fragments of which fields should be used for the row/column labels. The tool offers several advantages over traditional methods of analysis: (i) it supports a quantitative method of doing phonological research; (ii) it gives universal access to the same se...

  20. A relational database application in support of integrated neuroscience research.

    Science.gov (United States)

    Rudowsky, Ira; Kulyba, Olga; Kunin, Mikhail; Ogarodnikov, Dmitri; Raphan, Theodore

    2004-12-01

    The development of relational databases has significantly improved the performance of storage, search, and retrieval functions and has made it possible for applications that perform real-time data acquisition and analysis to interact with these types of databases. The purpose of this research was to develop a user interface for interaction between a data acquisition and analysis application and a relational database using the Oracle9i system. The overall system was designed to have an indexing capability that threads into the data acquisition and analysis programs. Tables were designed and relations within the database for indexing the files and information contained within the files were established. The system provides retrieval capabilities over a broad range of media, including analog, event, and video data types. The system's ability to interact with a data capturing program at the time of the experiment to create both multimedia files as well as the meta-data entries in the relational database avoids manual entries in the database and ensures data integrity and completeness for further interaction with the data by analysis applications.

  1. Gas Hydrate Research Database and Web Dissemination Channel

    Energy Technology Data Exchange (ETDEWEB)

    Micheal Frenkel; Kenneth Kroenlein; V Diky; R.D. Chirico; A. Kazakow; C.D. Muzny; M. Frenkel

    2009-09-30

    To facilitate advances in application of technologies pertaining to gas hydrates, a United States database containing experimentally-derived information about those materials was developed. The Clathrate Hydrate Physical Property Database (NIST Standard Reference Database {number_sign} 156) was developed by the TRC Group at NIST in Boulder, Colorado paralleling a highly-successful database of thermodynamic properties of molecular pure compounds and their mixtures and in association with an international effort on the part of CODATA to aid in international data sharing. Development and population of this database relied on the development of three components of information-processing infrastructure: (1) guided data capture (GDC) software designed to convert data and metadata into a well-organized, electronic format, (2) a relational data storage facility to accommodate all types of numerical and metadata within the scope of the project, and (3) a gas hydrate markup language (GHML) developed to standardize data communications between 'data producers' and 'data users'. Having developed the appropriate data storage and communication technologies, a web-based interface for both the new Clathrate Hydrate Physical Property Database, as well as Scientific Results from the Mallik 2002 Gas Hydrate Production Research Well Program was developed and deployed at http://gashydrates.nist.gov.

  2. GiSAO.db: a database for ageing research

    Directory of Open Access Journals (Sweden)

    Grillari Johannes

    2011-05-01

    Full Text Available Abstract Background Age-related gene expression patterns of Homo sapiens as well as of model organisms such as Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster are a basis for understanding the genetic mechanisms of ageing. For an effective analysis and interpretation of expression profiles it is necessary to store and manage huge amounts of data in an organized way, so that these data can be accessed and processed easily. Description GiSAO.db (Genes involved in senescence, apoptosis and oxidative stress database is a web-based database system for storing and retrieving ageing-related experimental data. Expression data of genes and miRNAs, annotation data like gene identifiers and GO terms, orthologs data and data of follow-up experiments are stored in the database. A user-friendly web application provides access to the stored data. KEGG pathways were incorporated and links to external databases augment the information in GiSAO.db. Search functions facilitate retrieval of data which can also be exported for further processing. Conclusions We have developed a centralized database that is very well suited for the management of data for ageing research. The database can be accessed at https://gisao.genome.tugraz.at and all the stored data can be viewed with a guest account.

  3. ERPDB: An Integrated Database of ERP Data for Neuroinformatics Research

    Directory of Open Access Journals (Sweden)

    QingHong Yan

    2007-10-01

    Full Text Available Event-related potential (ERP is the measurement of the brain's electrical activity in response to different types of events, such as attention, words, thinking, or sounds. By measuring the brain's response to such events, we can learn how different types of information are processed. As the mass of recorded ERP data explodes, an automatic and accurate tool to store, manage, and retrieve data readily is of increasing concern in neuroinformatics. In this paper, we describe a relational ERP database that has been constructed using the SQL server 2000 database management system and an IIS web server that has been setup for data retrieval through a custom web interface (http://202.113.232.103:8088/erpdb/index.asp. A novel database structure has been used to store ERP data of different activity channels, which provides a rapid and accurate way for data retrieval within any given range on the time zone with various searching options. The database is divided into: (1 subjects' information and record information and (2 ERP data, which has been structured and standardized in a database table supplemented with unrestricted text files. It can integrate or exchange data with other clinical databases or computer-based information systems through a program based on ADO techniques. Users are able to readily retrieve ERP data through the user-friendly web page interface. All online resources of the database are freely available to the scientific community. As the database develops further, we anticipate it will become a valuable tool that will make a great contribution to everyday clinical practice, teaching, and research work inneuroscience and psychology in the future.

  4. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The journal of Meteorological and Environmental Research[ISSN:2152-3940] has been included and stored by four famous databases:CAS,CABI,CSA and CNKI.CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  5. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The journal of Meteorological and Environmental Research [ISSN: 2152 -3940]has been included and stored by four fa-mous databases: CAS,CABI,CSA and CNKI.CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  6. Fedora Content Modelling for Improved Services for Research Databases

    DEFF Research Database (Denmark)

    Elbæk, Mikael Karstensen; Heller, Alfred; Pedersen, Gert Schmeltz

    A re-implementation of the research database of the Technical University of Denmark, DTU, is based on Fedora. The backbone consists of content models for primary and secondary entities and their relationships, giving flexible and powerful extraction capabilities for interoperability and reporting...

  7. DANBIO-powerful research database and electronic patient record

    DEFF Research Database (Denmark)

    Hetland, Merete Lund

    2011-01-01

    The nationwide DANBIO registry has been designed to capture operational clinical data as part of routine clinical care. At the same time, it provides a powerful research database. This article reviews the DANBIO registry with focus on problems and solutions of design, funding and linkage, provides...... is based on open-source software. Via a unique personal identification code, linkage with various national registers is possible for research purposes. Since the year 2000, more than 10,000 patients have been included. The main focus of research has been on treatment efficacy and drug survival. Compared...... as an electronic patient 'chronicle' in routine care, and at the same time provides a powerful research database....

  8. Databases

    Data.gov (United States)

    National Aeronautics and Space Administration — The databases of computational and experimental data from the first Aeroelastic Prediction Workshop are located here. The databases file names tell their contents by...

  9. DANBIO-powerful research database and electronic patient record

    DEFF Research Database (Denmark)

    Hetland, Merete Lund

    2011-01-01

    an overview of the research outcome and presents the cohorts of RA patients. The registry, which is approved as a national quality registry, includes patients with RA, PsA and AS, who are followed longitudinally. Data are captured electronically from the source (patients and health personnel). The IT platform...... as an electronic patient 'chronicle' in routine care, and at the same time provides a powerful research database....

  10. Public-domain software for root image analysis

    Directory of Open Access Journals (Sweden)

    Mirian Cristina Gomes Costa

    2014-10-01

    Full Text Available In the search for high efficiency in root studies, computational systems have been developed to analyze digital images. ImageJ and Safira are public-domain systems that may be used for image analysis of washed roots. However, differences in root properties measured using ImageJ and Safira are supposed. This study compared values of root length and surface area obtained with public-domain systems with values obtained by a reference method. Root samples were collected in a banana plantation in an area of a shallower Typic Carbonatic Haplic Cambisol (CXk, and an area of a deeper Typic Haplic Ta Eutrophic Cambisol (CXve, at six depths in five replications. Root images were digitized and the systems ImageJ and Safira used to determine root length and surface area. The line-intersect method modified by Tennant was used as reference; values of root length and surface area measured with the different systems were analyzed by Pearson's correlation coefficient and compared by the confidence interval and t-test. Both systems ImageJ and Safira had positive correlation coefficients with the reference method for root length and surface area data in CXk and CXve. The correlation coefficient ranged from 0.54 to 0.80, with lowest value observed for ImageJ in the measurement of surface area of roots sampled in CXve. The IC (95 % revealed that root length measurements with Safira did not differ from that with the reference method in CXk (-77.3 to 244.0 mm. Regarding surface area measurements, Safira did not differ from the reference method for samples collected in CXk (-530.6 to 565.8 mm² as well as in CXve (-4231 to 612.1 mm². However, measurements with ImageJ were different from those obtained by the reference method, underestimating length and surface area in samples collected in CXk and CXve. Both ImageJ and Safira allow an identification of increases or decreases in root length and surface area. However, Safira results for root length and surface area are

  11. Concierge: Personal database software for managing digital research resources

    Directory of Open Access Journals (Sweden)

    Hiroyuki Sakai

    2007-11-01

    Full Text Available This article introduces a desktop application, named Concierge, for managing personal digital research resources. Using simple operations, it enables storage of various types of files and indexes them based on content descriptions. A key feature of the software is a high level of extensibility. By installing optional plug-ins, users can customize and extend the usability of the software based on their needs. In this paper, we also introduce a few optional plug-ins: literaturemanagement, electronic laboratory notebook, and XooNlps client plug-ins. XooNIps is a content management system developed to share digital research resources among neuroscience communities. It has been adopted as the standard database system in Japanese neuroinformatics projects. Concierge, therefore, offers comprehensive support from management of personal digital research resources to their sharing in open-access neuroinformatics databases such as XooNIps. This interaction between personal and open-access neuroinformatics databases is expected to enhance the dissemination of digital research resources. Concierge is developed as an open source project; Mac OS X and Windows XP versions have been released at the official site (http://concierge.sourceforge.jp.

  12. Veterinary clinical research database for homeopathy: placebo-controlled trials.

    Science.gov (United States)

    Clausen, J; Albrecht, H; Mathie, R T

    2013-04-01

    Veterinary homeopathy has led a somewhat shadowy existence since its first introduction. Only in the last three decades has the number of clinical trials increased considerably. This literature is generally not well perceived, which may be partly a consequence of the diffuse and somewhat inaccessible nature of some of the relevant research publications. The Veterinary Clinical Research Database for Homeopathy (VetCR) was launched in 2006 to provide information on existing clinical research in veterinary homeopathy and to facilitate the preparation of systematic reviews. The aim of the present report is to provide an overview of this first database on clinical research in veterinary homeopathy, with a special focus on its content of placebo controlled clinical trials and summarising what is known about placebo effects in animals. In April 2012, the VetCR database contained 302 data records. Among these, 203 controlled trials were identified: 146 randomised and 57 non-randomised. In 97 of those 203 trials, the homeopathic medical intervention was compared to placebo. A program of formal systematic reviews of peer-reviewed randomised controlled trials in veterinary homeopathy is now underway; detailed findings from the program's data extraction and appraisal approach, including the assessment of trial quality (risk of bias), will be reported in due course. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Databases

    Directory of Open Access Journals (Sweden)

    Nick Ryan

    2004-01-01

    Full Text Available Databases are deeply embedded in archaeology, underpinning and supporting many aspects of the subject. However, as well as providing a means for storing, retrieving and modifying data, databases themselves must be a result of a detailed analysis and design process. This article looks at this process, and shows how the characteristics of data models affect the process of database design and implementation. The impact of the Internet on the development of databases is examined, and the article concludes with a discussion of a range of issues associated with the recording and management of archaeological data.

  14. About the Database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by five famous databases:CAS,CABI,CSA,EBSCO and CNKI. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive source for chemical information. Centre for Agriculture and Bioscience International(CABI) is a not-for-profit international

  15. About the Database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    正The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by five famous databases:CAS,CABI,CSA,EBSCO and CNKI. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive source for chemical information. Centre for Agriculture and Bioscience International(CABI) is a not-for-profit international

  16. A neuroinformatics database system for disease-oriented neuroimaging research.

    Science.gov (United States)

    Wong, Stephen T C; Hoo, Kent Soo; Cao, Xinhua; Tjandra, Donny; Fu, J C; Dillon, William P

    2004-03-01

    Clinical databases are continually growing and accruing more patient information. One of the challenges for managing this wealth of data is efficient retrieval and analysis of a broad range of image and non-image patient data from diverse data sources. This article describes the design and implementation of a new class of research data warehouse, neuroinformatics database system (NIDS), which will alleviate these problems for clinicians and researchers studying and treating patients with intractable temporal lobe epilepsy. The NIDS is a secured, multi-tier system that enables the user to gather, proofread, analyze, and store data from multiple underlying sources. In addition to data management, the NIDS provides several key functions including image analysis and processing, free text search of patient reports, construction of general queries, and on-line statistical analysis. The establishment of this integrated research database will serve as a foundation for future hypothesis-driven experiments, which could uncover previously unsuspected correlations and perhaps help to identify new and accurate predictors for image diagnosis.

  17. BAO Plate Archive Project: Digitization, Electronic Database and Research Programmes

    Science.gov (United States)

    Mickaelian, A. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Farmanyan, S. V.; Gigoyan, K. S.; Gyulzadyan, M. V.; Khachatryan, K. G.; Knyazyan, A. V.; Kostandyan, G. R.; Mikayelyan, G. A.; Nikoghosyan, E. H.; Paronyan, G. M.; Vardanyan, A. V.

    2016-06-01

    The most important part of the astronomical observational heritage are astronomical plate archives created on the basis of numerous observations at many observatories. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,000 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt type and other smaller telescopes during 1947-1991. In 2002-2005, the famous Markarian Survey (also called First Byurakan Survey, FBS) 1874 plates were digitized and the Digitized FBS (DFBS) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. A large project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage was started in 2015. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 11 astronomers and 2 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database will be used to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects, mainly including high proper motion stars, variable objects and Solar System bodies.

  18. Systematic analysis of public domain compound potency data identifies selective molecular scaffolds across druggable target families.

    Science.gov (United States)

    Hu, Ye; Wassermann, Anne Mai; Lounkine, Eugen; Bajorath, Jürgen

    2010-01-28

    Molecular scaffolds that yield target family-selective compounds are of high interest in pharmaceutical research. There continues to be considerable debate in the field as to whether chemotypes with a priori selectivity for given target families and/or targets exist and how they might be identified. What do currently available data tell us? We present a systematic and comprehensive selectivity-centric analysis of public domain target-ligand interactions. More than 200 molecular scaffolds are identified in currently available active compounds that are selective for established target families. A subset of these scaffolds is found to produce compounds with high selectivity for individual targets among closely related ones. These scaffolds are currently underrepresented in approved drugs.

  19. XML Database Researching%XML数据库技术研究

    Institute of Scientific and Technical Information of China (English)

    秦杰; 杨树强; 窦文华

    2003-01-01

    XML database is a new database technology. This paper gives an overview about the last research aboutXML database and its related productions,then comparing XML database with traditional RDBMS. We analyze andpoint out some weaknesses about XML database,and give out our viewpoint.

  20. Research Groups & Research Subjects - RED | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available rch Groups & Research Subjects Data detail Data name Research Groups & Research Sub... Number of data entries 174 entries Data item Description Research ID Research ID (Subject number) Institute...tion Download License Update History of This Database Site Policy | Contact Us Research Groups & Research Subjects - RED | LSDB Archive ... ...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us RED Resea... Organization Section Section (Department) User name User name Experimental title Experimental title (Rese

  1. An outlook on the nature of mental creations after belonging to public domain

    Directory of Open Access Journals (Sweden)

    Pedjman Mohammadi

    2015-05-01

    Full Text Available The public domain of copyright which considers the end of protection period, attempts to cause balance among the rights of authors, society and third parties. So at the end of financial rights of author’s protection period the possibility of free utilization of these literary works will be possible. But in this situation one of the controversial difficulties is the nature of these kinds of literary works which, according to some scholars, after belonging to public domain, they will change in to the Allowable. To approve their idea, they focus on common features existing in these literary works(works relating to public domain and the Allowable. On the other hand it is believed that literary works after belonging to public domain essentially works after belonging to public domain essentially due to lacking of scarcity element are not considered property at all.

  2. Plant database resources at The Institute for Genomic Research.

    Science.gov (United States)

    Chan, Agnes P; Rabinowicz, Pablo D; Quackenbush, John; Buell, C Robin; Town, Chris D

    2007-01-01

    With the completion of the genome sequences of the model plants Arabidopsis and rice, and the continuing sequencing efforts of other economically important crop plants, an unprecedented amount of genome sequence data is now available for large-scale genomics studies and analyses, such as the identification and discovery of novel genes, comparative genomics, and functional genomics. Efficient utilization of these large data sets is critically dependent on the ease of access and organization of the data. The plant databases at The Institute for Genomic Research (TIGR) have been set up to maintain various data types including genomic sequence, annotation and analyses, expressed transcript assemblies and analyses, and gene expression profiles from microarray studies. We present here an overview of the TIGR database resources for plant genomics and describe methods to access the data.

  3. Toward an Ontology-Based Framework for Clinical Research Databases

    Science.gov (United States)

    Kong, Y. Megan; Dahlke, Carl; Xiang, Qun; Qian, Yu; Karp, David; Scheuermann, Richard H.

    2010-01-01

    Clinical research includes a wide range of study designs from focused observational studies to complex interventional studies with multiple study arms, treatment and assessment events, and specimen procurement procedures. Participant characteristics from case report forms need to be integrated with molecular characteristics from mechanistic experiments on procured specimens. In order to capture and manage this diverse array of data, we have developed the Ontology-Based eXtensible conceptual model (OBX) to serve as a framework for clinical research data in the Immunology Database and Analysis Portal (ImmPort). By designing OBX around the logical structure of the Basic Formal Ontology (BFO) and the Ontology for Biomedical Investigations (OBI), we have found that a relatively simple conceptual model can represent the relatively complex domain of clinical research. In addition, the common framework provided by BFO makes it straightforward to develop data dictionaries based on reference and application ontologies from the OBO Foundry. PMID:20460173

  4. Secondary analysis of large databases for hepatology research.

    Science.gov (United States)

    Okafor, Philip N; Chiejina, Maria; de Pretis, Nicolo; Talwalkar, Jayant A

    2016-04-01

    Secondary analysis of large datasets involves the utilization of existing data that has typically been collected for other purposes to advance scientific knowledge. This is an established methodology applied in health services research with the unique advantage of efficiently identifying relationships between predictor and outcome variables but which has been underutilized for hepatology research. Our review of 1431 abstracts published in the 2013 European Association for the Study of Liver (EASL) abstract book showed that less than 0.5% of published abstracts utilized secondary analysis of large database methodologies. This review paper describes existing large datasets that can be exploited for secondary analyses in liver disease research. It also suggests potential questions that could be addressed using these data warehouses and highlights the strengths and limitations of each dataset as described by authors that have previously used them. The overall goal is to bring these datasets to the attention of readers and ultimately encourage the consideration of secondary analysis of large database methodologies for the advancement of hepatology.

  5. Influenza research database: an integrated bioinformatics resource for influenza virus research

    Science.gov (United States)

    The Influenza Research Database (IRD) is a U.S. National Institute of Allergy and Infectious Diseases (NIAID)-sponsored Bioinformatics Resource Center dedicated to providing bioinformatics support for influenza virus research. IRD facilitates the research and development of vaccines, diagnostics, an...

  6. Intra-disciplinary differences in database coverage and the consequences for bibliometric research

    DEFF Research Database (Denmark)

    Faber Frandsen, Tove; Nicolaisen, Jeppe

    2008-01-01

    disciplines focusing on interdisciplinary differences; however, little is known about the potential existence of intradisciplinary differences in database coverage. Focusing on intradisciplinary differences, the article documents large database-coverage differences within two disciplines (economics......Bibliographic databases (including databases based on open access) are routinely used for bibliometric research. The value of a specific database depends to a large extent on the coverage of the discipline(s) under study. A number of studies have determined the coverage of databases in specific...

  7. Knowledge map of artemisinin research in SCI and Medline database

    Directory of Open Access Journals (Sweden)

    Qiang Yao , Jing Chen , Peng-Hui Lyu , Shi-Jing Zhang , Fei-Cheng Ma & Jian-Guo Fang

    2012-12-01

    Full Text Available Background & objectives: Artemisinin was first extracted from the herb Artemisia annua which has been used formany centuries in Chinese traditional medicine as a treatment for fever and malaria. It has been given the 2011Lasker-DeBakey clinical medical research award. In this paper, knowledge map of artemisinin research wasdrawn to provide some information for global researchers interested in artemisinin and its relevant references.Methods: In this work, bibliometric analysis and knowledge visualization technology were applied to evaluateglobal scientific production and developing trend of artemisinin research through Science Citation Index (SCIpapers and Medline papers with online version published as following aspects: publication outputs, subjectcategories, journals, countries, international collaboration, citations, authorship and co-authorship, author keywords and co-words analysis. The Thomson Data Analyzer (TDA, Netdraw and Aureka software were employedto analyze the SCI as well as Medline papers data for knowledge mapping.Results: Global literature of artemisinin research has increased rapidly over the past 30 years and has boosted inrecent years. Seen from the statistical study in many aspects, Pharmacology & Pharmacy, and Chemistry are stillthe main subjects of artemisinin research with parasitology and tropical medicine increasing quickly. MalariaJournal and American Journal of Tropical Medicine are top productive journals both in SCI and Medline databases.Quantity and quality of papers in US are in a leading position, although papers quantity and active degree indeveloping countries such as P.R. China, Thailand and India are relatively high, the quality of papers from thesecountries needs to be improved. New emerging key words and co-words remind us that mechanism of action,pharmacokinetics, artemisinin-based alternatives, etc. are the future trends of artemisinin research.Conclusion: Through bibliometric analysis the development

  8. Developing a personal computer-based data visualization system using public domain software

    Science.gov (United States)

    Chen, Philip C.

    1999-03-01

    The current research will investigate the possibility of developing a computing-visualization system using a public domain software system built on a personal computer. Visualization Toolkit (VTK) is available on UNIX and PC platforms. VTK uses C++ to build an executable. It has abundant programming classes/objects that are contained in the system library. Users can also develop their own classes/objects in addition to those existing in the class library. Users can develop applications with any of the C++, Tcl/Tk, and JAVA environments. The present research will show how a data visualization system can be developed with VTK running on a personal computer. The topics will include: execution efficiency; visual object quality; availability of the user interface design; and exploring the feasibility of the VTK-based World Wide Web data visualization system. The present research will feature a case study showing how to use VTK to visualize meteorological data with techniques including, iso-surface, volume rendering, vector display, and composite analysis. The study also shows how the VTK outline, axes, and two-dimensional annotation text and title are enhancing the data presentation. The present research will also demonstrate how VTK works in an internet environment while accessing an executable with a JAVA application programing in a webpage.

  9. Middle East, North Africa and Western Eurasia Seismic Research Database

    Energy Technology Data Exchange (ETDEWEB)

    O' Boyle, J L; Ruppert, S D; Hauk, T F; Dodge, D A; Ganzberger, M D; Ryall, F

    2003-07-14

    The National Nuclear Security Administration (NNSA) Ground-Based Nuclear Explosion Monitoring Research and Engineering (GNEM R&E) Program at Lawrence Livermore National Laboratory (LLNL) has made significant progress populating a comprehensive Seismic Research Database (SRDB) used for deriving seismic calibration parameters for the Middle East, North Africa and Western Eurasia (ME/NA/WE) regions. In addition to an overview of select individual information products, we present an overview of our visualization, integration, validation, and organizational processes. Development of these processes and the LLNL SRDB was necessitated by both the very large amount of data and information involved (over 15 terabytes) and the varied data and research result formats utilized. The LLNL SRDB allows for the collection of raw and contextual seismic data used in research, provides an interface for researchers to access data, provides a framework to store research results and integrate datasets, and supports assembly, integration and dissemination of datasets to the NNSA Knowledge Base (KB). The LLNL SRDB is a flexible and extensible framework consisting of a relational database (RDB), Geographical Information System (GIS), and associated product/data visualization and data management tools. This framework is designed to accommodate large volumes of data in diverse formats from many sources (both in-house-derived research and integrated contractor products), in addition to maintaining detailed quality control and metadata. In order to efficiently organize information within the LLNL SRDB, it was necessary to automate procedures needed to create and update database tables, but a large effort is still required by technicians and scientists to load special datasets, review results of automated processing and resolve quality issues. The LLNL SRDB currently has 3 million reconciled event origins and arrivals from several global, regional and local seismic bulletins and 30 million

  10. LLNL Middle East and North Africa research database

    Energy Technology Data Exchange (ETDEWEB)

    Ruppert, S.D.; Hauk, T.F.; Leach, R.

    1997-07-15

    The Lawrence Livermore National Laboratory (LLNL) CTBT R{ampersand}D program has made significant progress assembling a comprehensive seismic database (DB) for events and derived parameters in the Middle East and North Africa (ME/NA). The LLNL research DB provides not only a coherent framework in which store and organize large volumes of collected seismic waveforms and associated event parameter information but also provides an efficient data processing/research environment. The DB is designed to be flexible and extensible in order to accommodate the large volumes of data in diverse formats from many sources in addition to maintaining detailed quality control and metadata. Researchers can make use of the relational nature of the DB and interactive analysis tools to quickly and efficiently process large volumes of data. Seismic waveforms have been systematically collected form a wide range of local and regional networks using numerous earthquake bulletins and converted a common format based on CSS3.O while undergoing quality control and corrections of errors. By combining traveltime observations, event characterization studies, and regional wave-propagation studies of the LLNL CTBT team, we are assembling a library of ground truth information and event location correction surfaces required to support the ME/NA regionalization program. Corrections and parameters distilled from the LLNL research DB will provide needed contributions to the DOE knowledge base for the ME/NA region and enable the USNDC and IDC to effectively verify CTBT compliance.

  11. The GUDMAP database – an online resource for genitourinary research

    Science.gov (United States)

    Harding, Simon D.; Armit, Chris; Armstrong, Jane; Brennan, Jane; Cheng, Ying; Haggarty, Bernard; Houghton, Derek; Lloyd-MacGilp, Sue; Pi, Xingjun; Roochun, Yogmatee; Sharghi, Mehran; Tindal, Christopher; McMahon, Andrew P.; Gottesman, Brian; Little, Melissa H.; Georgas, Kylie; Aronow, Bruce J.; Potter, S. Steven; Brunskill, Eric W.; Southard-Smith, E. Michelle; Mendelsohn, Cathy; Baldock, Richard A.; Davies, Jamie A.; Davidson, Duncan

    2011-01-01

    The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research. PMID:21652655

  12. The GUDMAP database--an online resource for genitourinary research.

    Science.gov (United States)

    Harding, Simon D; Armit, Chris; Armstrong, Jane; Brennan, Jane; Cheng, Ying; Haggarty, Bernard; Houghton, Derek; Lloyd-MacGilp, Sue; Pi, Xingjun; Roochun, Yogmatee; Sharghi, Mehran; Tindal, Christopher; McMahon, Andrew P; Gottesman, Brian; Little, Melissa H; Georgas, Kylie; Aronow, Bruce J; Potter, S Steven; Brunskill, Eric W; Southard-Smith, E Michelle; Mendelsohn, Cathy; Baldock, Richard A; Davies, Jamie A; Davidson, Duncan

    2011-07-01

    The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.

  13. Development of a combined database for meta-epidemiological research

    DEFF Research Database (Denmark)

    Savović, Jelena; Harris, Ross J; Wood, Lesley

    2010-01-01

    Collections of meta-analyses assembled in meta-epidemiological studies are used to study associations of trial characteristics with intervention effect estimates. However, methods and findings are not consistent across studies. To combine data from 10 meta-epidemiological studies into a single da...... database will be used to examine the combined evidence on sources of bias in randomized controlled trials. The strategy used to remove overlap between meta-analyses may be of use for future empirical research. Copyright © 2010 John Wiley & Sons, Ltd.......Collections of meta-analyses assembled in meta-epidemiological studies are used to study associations of trial characteristics with intervention effect estimates. However, methods and findings are not consistent across studies. To combine data from 10 meta-epidemiological studies into a single...

  14. University Real Estate Development Database: A Database-Driven Internet Research Tool

    Science.gov (United States)

    Wiewel, Wim; Kunst, Kara

    2008-01-01

    The University Real Estate Development Database is an Internet resource developed by the University of Baltimore for the Lincoln Institute of Land Policy, containing over six hundred cases of university expansion outside of traditional campus boundaries. The University Real Estate Development database is a searchable collection of real estate…

  15. University Real Estate Development Database: A Database-Driven Internet Research Tool

    Science.gov (United States)

    Wiewel, Wim; Kunst, Kara

    2008-01-01

    The University Real Estate Development Database is an Internet resource developed by the University of Baltimore for the Lincoln Institute of Land Policy, containing over six hundred cases of university expansion outside of traditional campus boundaries. The University Real Estate Development database is a searchable collection of real estate…

  16. Research Note on the Energy Infrastructure Attack Database (EIAD

    Directory of Open Access Journals (Sweden)

    Jennifer Giroux

    2013-12-01

    Full Text Available The January 2013 attack on the In Amenas natural gas facility drew international attention. However this attack is part of a portrait of energy infrastructure targeting by non-state actors that spans the globe. Data drawn from the Energy Infrastructure Attack Database (EIAD shows that in the last decade there were, on average, nearly 400 annual attacks carried out by armed non-state actors on energy infrastructure worldwide, a figure that was well under 200 prior to 1999. This data reveals a global picture whereby violent non-state actors target energy infrastructures to air grievances, communicate to governments, impact state economic interests, or capture revenue in the form of hijacking, kidnapping ransoms, theft. And, for politically motivated groups, such as those engaged in insurgencies, attacking industry assets garners media coverage serving as a facilitator for international attention. This research note will introduce EIAD and position its utility within various research areas where the targeting of energy infrastructure, or more broadly energy infrastructure vulnerability, has been addressed, either directly or indirectly. We also provide a snapshot of the initial analysis of the data between 1980-2011, noting specific temporal and spatial trends, and then conclude with a brief discussion on the contribution of EIAD, highlighting future research trajectories. 

  17. Development of mooring-anchor program in public domain for coupling with floater program for FOWTs (Floating Offshore Wind Turbines)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, MooHyun [American Bureau of Shipping (ABS), Houston, TX (United States)

    2014-08-01

    This report presents the development of offshore anchor data sets which are intended to be used to develop a database that allows preliminary selection and sizing of anchors for the conceptual design of floating offshore wind turbines (FOWTs). The study is part of a project entitled “Development of Mooring-Anchor Program in Public Domain for Coupling with Floater Program for FOWTs (Floating Offshore Wind Turbines)”, under the direction of Dr. Moo-Hyun Kim at the Texas A&M University and with the sponsorship from the US Department of Energy (Contract No. DE-EE0005479, CFDA # 81.087 for DE-FOA-0000415, Topic Area 1.3: Subsurface Mooring and Anchoring Dynamics Models).

  18. Database security and encryption technology research and application

    Science.gov (United States)

    Zhu, Li-juan

    2013-03-01

    The main purpose of this paper is to discuss the current database information leakage problem, and discuss the important role played by the message encryption techniques in database security, As well as MD5 encryption technology principle and the use in the field of website or application. This article is divided into introduction, the overview of the MD5 encryption technology, the use of MD5 encryption technology and the final summary. In the field of requirements and application, this paper makes readers more detailed and clearly understood the principle, the importance in database security, and the use of MD5 encryption technology.

  19. Materialities of Law: Celebrity Production and the Public Domain

    Directory of Open Access Journals (Sweden)

    Esther Milne

    2009-12-01

    Full Text Available Celebrity production and consumption are powerful socio-economic forces. The celebrity functions as a significant economic resource for the commercial sector and plays a fundamental symbolic role within culture by providing a shared ‘vocabulary’ through which to understand contemporary social relations. A pivotal element of this allure is the process by which the celebrity figure is able to forge an intimate link with its audience, often producing public expressions of profound compassion, respect or revulsion. This process, however, is complicated by emerging participatory media forms whose impact is experienced as new conditions of possibility for celebrity production and consumption. As Marshall argues, video mash-ups of celebrity interviews, such as those of Christian Bale or Tom Cruise, are dramatically changing the relation between celebrity and audience (Marshall, 2006: 640. Meanings produced by these audience remixes challenge the extent to which a celebrity might control her image. So is the celebrity personality, therefore, a public or private commodity? Who owns the celebrity image within remix culture? Although the celebrity figure has been thoroughly researched in relation to its patterns of consumption; semiotic power; and industry construction; less attention has been focused on the forms of celebrity governance enabled by legislative and case law settings. How might the law deal with the significant economic and cultural power exercised within celebrity culture?

  20. Suburban development – a search for public domains in Danish suburban neighbourhoods

    DEFF Research Database (Denmark)

    Melgaard, Bente; Bech-Danielsen, Claus

    , potentials for bridge-building across the enclaves of the suburb are looked for through a combined architectural-anthropological mapping of public spaces in a specific suburb in Denmark, the analyses being carried out in the light of Hajer & Reijndorp’s definition of public domains and the term exchange....... The results so far show that suburban spaces with a potential for creating bridge-building across the segregated enclaves do exist but that, among other things, focus on spatial design is needed before actual public domains creating the basis for exchange are achieved....

  1. Economic evaluation databases as an aid to healthcare decision makers and researchers.

    Science.gov (United States)

    Aguiar-Ibáñez, Raquel; Nixon, John; Glanville, Julie; Craig, Dawn; Rice, Stephen; Christie, James; Drummond, Michael F

    2005-12-01

    Economic evaluation databases have been developed to assist in setting priorities and facilitating research within the healthcare sector. This paper presents an overview of the major databases of economic evaluations currently available (HEED, NHS EED, the CEA Registry, CODECS, PEDE, EURONHEED and JEED). It describes the key features of each database and the main user groups. It also presents evidence of the value of access to economic evaluation databases, particularly for the researchers and decision makers who form their main target audience. The research available shows that both decision makers and researchers find economic evaluation databases helpful as a source of information. However, database producers may also need to better understand the requirements of their users and consider adaptations to their products.

  2. Long non-coding RNA Databases in Cardiovascular Research

    Institute of Scientific and Technical Information of China (English)

    Frank Ruhle; Monika Stoll

    2016-01-01

    With the rising interest in the regulatory functions of long non-coding RNAs (lncRNAs) in complex human diseases such as cardiovascular diseases, there is an increasing need in public databases offering comprehensive and integrative data for all aspects of these versatile molecules. Recently, a variety of public data repositories that specialized in lncRNAs have been developed, which make use of huge high-throughput data particularly from next-generation sequencing (NGS) approaches. Here, we provide an overview of current lncRNA databases covering basic and functional annotation, lncRNA expression and regulation, interactions with other biomole-cules, and genomic variants influencing the structure and function of lncRNAs. The prominent lncRNA antisense noncoding RNA in the INK4 locus (ANRIL), which has been unequivocally associated with coronary artery disease through genome-wide association studies (GWAS), serves as an example to demonstrate the features of each individual database.

  3. The 24th annual Nucleic Acids Research database issue: a look back and upcoming changes

    Science.gov (United States)

    Galperin, Michael Y.; Fernández-Suárez, Xosé M.; Rigden, Daniel J.

    2017-01-01

    This year's Database Issue of Nucleic Acids Research contains 152 papers that include descriptions of 54 new databases and update papers on 98 databases, of which 16 have not been previously featured in NAR. As always, these databases cover a broad range of molecular biology subjects, including genome structure, gene expression and its regulation, proteins, protein domains, and protein–protein interactions. Following the recent trend, an increasing number of new and established databases deal with the issues of human health, from cancer-causing mutations to drugs and drug targets. In accordance with this trend, three recently compiled databases that have been selected by NAR reviewers and editors as ‘breakthrough’ contributions, denovo-db, the Monarch Initiative, and Open Targets, cover human de novo gene variants, disease-related phenotypes in model organisms, and a bioinformatics platform for therapeutic target identification and validation, respectively. We expect these databases to attract the attention of numerous researchers working in various areas of genetics and genomics. Looking back at the past 12 years, we present here the ‘golden set’ of databases that have consistently served as authoritative, comprehensive, and convenient data resources widely used by the entire community and offer some lessons on what makes a successful database. The Database Issue is freely available online at the https://academic.oup.com/nar web site. An updated version of the NAR Molecular Biology Database Collection is available at http://www.oxfordjournals.org/nar/database/a/. PMID:28053160

  4. Comprehensiveness of "Social Work Abstracts" as a Database for Researchers and Practitioners

    Science.gov (United States)

    Shek, Daniel T. L.

    2008-01-01

    Objective: The comprehensiveness of "Social Work Abstracts (SWA)" as a database was examined. Method: The coverage of articles of "Research on Social Work Practice" and "Social Work Research" in "SWA" from 1995 to 2005 was examined. "SWA" was compared with other databases on several dimensions. A case study based on the author's publications was…

  5. National Databases with Information on College Students with Disabilities. NCCSD Research Brief. Volume 1, Issue 1

    Science.gov (United States)

    Avellone, Lauren; Scott, Sally

    2017-01-01

    The purpose of this research brief was to identify and provide an overview of national databases containing information about college students with disabilities. Eleven instruments from federal and university-based sources were described. Databases reflect a variety of survey methods, respondents, definitions of disability, and research questions.…

  6. Comprehensiveness of "Social Work Abstracts" as a Database for Researchers and Practitioners

    Science.gov (United States)

    Shek, Daniel T. L.

    2008-01-01

    Objective: The comprehensiveness of "Social Work Abstracts (SWA)" as a database was examined. Method: The coverage of articles of "Research on Social Work Practice" and "Social Work Research" in "SWA" from 1995 to 2005 was examined. "SWA" was compared with other databases on several dimensions. A case study based on the author's publications was…

  7. Research of database-based modeling for mining management system

    Institute of Scientific and Technical Information of China (English)

    WU Hai-feng; JIN Zhi-xin; BAI Xi-jun

    2005-01-01

    Put forward the method to construct the simulation model automatically with database-based automatic modeling(DBAM) for mining system. Designed the standard simulation model linked with some open cut Pautomobile dispatch system. Analyzed and finded out the law among them, and designed model maker to realize the automatic programming of the new model program.

  8. Research and development of Chinese LCA database and LCA software

    Institute of Scientific and Technical Information of China (English)

    GONG Xianzheng; NIE Zuoren; Wang Zhihong; ZUO Tieyong

    2006-01-01

    This paper detailed introduces the related work for building Chinese National Database, Sinocenter, of materials life cycle assessment (MLCA) and developing the environmental burden dataset of materials.The MLCA database was built in 2004, and the basic framework mainly includes LCA methodology, materials environmental dataset about energy consumption, resource input and environmental emissions.Nowadays, the database contains about fifty-thousand records of the main materials industries, such as cement, iron and steel, nonferrous metal, etc., and also includes the primary LCI data of fossil fuels and electricity grid in China.At the same time, the LCA method localization work is going on, for instance, calculated the resource characterization factors of 42 kinds of metal and 58 sorts of nonmetal, and also obtained some heavy metal impact factors in water.Based on the database, the iron and steel dataset has been developed with the data quality analysis, and some environmental burden data could be queried in our website, www.cnmlca.com, in the future.Lastly, according to the framework of the ISO14040 series standards, the antitype of Chinese LCA evaluation system was developed to support materials and products LCA evaluation in China.

  9. Data recycling: using existing databases to increase research capacity in speech-language development and disorders.

    Science.gov (United States)

    Justice, Laura M; Breit-Smith, Allison; Rogers, Margaret

    2010-01-01

    This clinical forum was organized to provide a means for informing the research and clinical communities of one mechanism through which research capacity might be enhanced within the field of speech-language pathology. Specifically, forum authors describe the process of conducting secondary analyses of extant databases to answer questions of relevance to speech and language development and disorders. This prologue defines the concept of secondary analysis of databases and provides an overview of each of the articles that make up the forum. Researchers invested in addressing basic and applied problems of relevance to speech and language services in schools can make use of a variety of extant databases to increase research capacity.

  10. Healthcare Databases in Thailand and Japan: Potential Sources for Health Technology Assessment Research.

    Science.gov (United States)

    Saokaew, Surasak; Sugimoto, Takashi; Kamae, Isao; Pratoomsoot, Chayanin; Chaiyakunapruk, Nathorn

    2015-01-01

    Health technology assessment (HTA) has been continuously used for value-based healthcare decisions over the last decade. Healthcare databases represent an important source of information for HTA, which has seen a surge in use in Western countries. Although HTA agencies have been established in Asia-Pacific region, application and understanding of healthcare databases for HTA is rather limited. Thus, we reviewed existing databases to assess their potential for HTA in Thailand where HTA has been used officially and Japan where HTA is going to be officially introduced. Existing healthcare databases in Thailand and Japan were compiled and reviewed. Databases' characteristics e.g. name of database, host, scope/objective, time/sample size, design, data collection method, population/sample, and variables were described. Databases were assessed for its potential HTA use in terms of safety/efficacy/effectiveness, social/ethical, organization/professional, economic, and epidemiological domains. Request route for each database was also provided. Forty databases- 20 from Thailand and 20 from Japan-were included. These comprised of national censuses, surveys, registries, administrative data, and claimed databases. All databases were potentially used for epidemiological studies. In addition, data on mortality, morbidity, disability, adverse events, quality of life, service/technology utilization, length of stay, and economics were also found in some databases. However, access to patient-level data was limited since information about the databases was not available on public sources. Our findings have shown that existing databases provided valuable information for HTA research with limitation on accessibility. Mutual dialogue on healthcare database development and usage for HTA among Asia-Pacific region is needed.

  11. [Musculoskeletal shock wave therapy--current database of clinical research].

    Science.gov (United States)

    Rompe, J D; Buch, M; Gerdesmeyer, L; Haake, M; Loew, M; Maier, M; Heine, J

    2002-01-01

    During the past decade application of extracorporal shock waves became an established procedure for the treatment of various musculoskeletal diseases in Germany. Up to now the positive results of prospective randomised controlled trials have been published for the treatment of plantar fasciitis, lateral elbow epicondylitis (tennis elbow), and of calcifying tendinitis of the rotator cuff. Most recently, contradicting results of prospective randomised placebo-controlled trials with adequate sample size calculation have been reported. The goal of this review is to present information about the current clinical database on extracorporeal shock wave treatment (ESWT).

  12. 37 CFR 201.26 - Recordation of documents pertaining to computer shareware and donation of public domain computer...

    Science.gov (United States)

    2010-07-01

    ... pertaining to computer shareware and donation of public domain computer software. 201.26 Section 201.26... GENERAL PROVISIONS § 201.26 Recordation of documents pertaining to computer shareware and donation of public domain computer software. (a) General. This section prescribes the procedures for submission of...

  13. 32 CFR 644.24 - Acquisition by Transfer from other Government Departments or Agencies (except Public Domain).

    Science.gov (United States)

    2010-07-01

    ... Departments or Agencies (except Public Domain). 644.24 Section 644.24 National Defense Department of Defense... Departments or Agencies (except Public Domain). When a requirement develops for the acquisition of Government... of existing improvements, the estimated cost of the proposed construction, attitude of the...

  14. The Use of a Relational Database in Qualitative Research on Educational Computing.

    Science.gov (United States)

    Winer, Laura R.; Carriere, Mario

    1990-01-01

    Discusses the use of a relational database as a data management and analysis tool for nonexperimental qualitative research, and describes the use of the Reflex Plus database in the Vitrine 2001 project in Quebec to study computer-based learning environments. Information systems are also discussed, and the use of a conceptual model is explained.…

  15. The ECLS-K Study and Database: A Resource for School Social Work Practitioners and Researchers

    Science.gov (United States)

    Williams, Sheara A.

    2008-01-01

    The purpose of this article is to introduce the Early Childhood Longitudinal Study-Kindergarten (ECLS-K) database to school social work practitioners and researchers. This database not only serves as a viable source for evidence-based practice pertaining to the influences of families and schools on the academic achievement of children beginning at…

  16. Open-Access Metabolomics Databases for Natural Product Research: Present Capabilities and Future Potential

    Science.gov (United States)

    Johnson, Sean R.; Lange, Bernd Markus

    2015-01-01

    Various databases have been developed to aid in assigning structures to spectral peaks observed in metabolomics experiments. In this review article, we discuss the utility of currently available open-access spectral and chemical databases for natural products discovery. We also provide recommendations on how the research community can contribute to further improvements. PMID:25789275

  17. Safety features in nuclear power plants to eliminate the need of emergency planning in public domain

    Indian Academy of Sciences (India)

    P K Vijayan; M T Kamble; A K Nayak; K K Vaze; R K Sinha

    2013-10-01

    Following the Fukushima accident, the safety features of Nuclear Power Plants (NPP) are being re-examined worldwide including India to demonstrate capabilities to cope with severe accidents. In order to restore public confidence and support for nuclear power, it is felt necessary to design future NPPs with near zero impact outside the plant boundary and thus enabling elimination of emergency planning in public domain. Authors have identified a set of safety features which are needed to be incorporated in advanced reactors to achieve this goal. These features enabling prevention, termination, mitigation and containment of radioactivity for beyond design basis accidents arising from extreme natural events are essential for achieving the goal of elimination of emergency planning in public domain. Inherent safety characteristics, passive and engineered safety features to achieve these functions are discussed in this paper. Present trends and future developments in this direction are also described briefly.

  18. Design of a decentralized reusable research database architecture to support data acquisition in large research projects.

    Science.gov (United States)

    Iavindrasana, Jimison; Depeursinge, Adrien; Ruch, Patrick; Spahni, Stéphane; Geissbuhler, Antoine; Müller, Henning

    2007-01-01

    The diagnostic and therapeutic processes, as well as the development of new treatments, are hindered by the fragmentation of information which underlies them. In a multi-institutional research study database, the clinical information system (CIS) contains the primary data input. An important part of the money of large scale clinical studies is often paid for data creation and maintenance. The objective of this work is to design a decentralized, scalable, reusable database architecture with lower maintenance costs for managing and integrating distributed heterogeneous data required as basis for a large-scale research project. Technical and legal aspects are taken into account based on various use case scenarios. The architecture contains 4 layers: data storage and access are decentralized at their production source, a connector as a proxy between the CIS and the external world, an information mediator as a data access point and the client side. The proposed design will be implemented inside six clinical centers participating in the @neurIST project as part of a larger system on data integration and reuse for aneurism treatment.

  19. Landslide databases for applied landslide impact research: the example of the landslide database for the Federal Republic of Germany

    Science.gov (United States)

    Damm, Bodo; Klose, Martin

    2014-05-01

    This contribution presents an initiative to develop a national landslide database for the Federal Republic of Germany. It highlights structure and contents of the landslide database and outlines its major data sources and the strategy of information retrieval. Furthermore, the contribution exemplifies the database potentials in applied landslide impact research, including statistics of landslide damage, repair, and mitigation. The landslide database offers due to systematic regional data compilation a differentiated data pool of more than 5,000 data sets and over 13,000 single data files. It dates back to 1137 AD and covers landslide sites throughout Germany. In seven main data blocks, the landslide database stores besides information on landslide types, dimensions, and processes, additional data on soil and bedrock properties, geomorphometry, and climatic or other major triggering events. A peculiarity of this landslide database is its storage of data sets on land use effects, damage impacts, hazard mitigation, and landslide costs. Compilation of landslide data is based on a two-tier strategy of data collection. The first step of information retrieval includes systematic web content mining and exploration of online archives of emergency agencies, fire and police departments, and news organizations. Using web and RSS feeds and soon also a focused web crawler, this enables effective nationwide data collection for recent landslides. On the basis of this information, in-depth data mining is performed to deepen and diversify the data pool in key landslide areas. This enables to gather detailed landslide information from, amongst others, agency records, geotechnical reports, climate statistics, maps, and satellite imagery. Landslide data is extracted from these information sources using a mix of methods, including statistical techniques, imagery analysis, and qualitative text interpretation. The landslide database is currently migrated to a spatial database system

  20. Impact of IPAD on CAD/CAM database university research

    Science.gov (United States)

    Leach, L. M.; Wozny, M. J.

    1984-01-01

    IPAD program has provided direction, focus and software products which impacted on CAD/CAM data base research and follow-on research. The relationship of IPAD to the research projects which involve the storage of geometric data in common data ase facilities such as data base machines, the exchange of data between heterogeneous data bases, the development of IGES processors, the migration of lrge CAD/CAM data base management systems to noncompatible hosts, and the value of RIM as a research tool is described.

  1. Development and testing of a database of NIH research funding of AAPM members: A report from the AAPM Working Group for the Development of a Research Database (WGDRD).

    Science.gov (United States)

    Whelan, Brendan; Moros, Eduardo G; Fahrig, Rebecca; Deye, James; Yi, Thomas; Woodward, Michael; Keall, Paul; Siewerdsen, Jeff H

    2017-04-01

    To produce and maintain a database of National Institutes of Health (NIH) funding of the American Association of Physicists in Medicine (AAPM) members, to perform a top-level analysis of these data, and to make these data (hereafter referred to as the AAPM research database) available for the use of the AAPM and its members. NIH-funded research dating back to 1985 is available for public download through the NIH exporter website, and AAPM membership information dating back to 2002 was supplied by the AAPM. To link these two sources of data, a data mining algorithm was developed in Matlab. The false-positive rate was manually estimated based on a random sample of 100 records, and the false-negative rate was assessed by comparing against 99 member-supplied PI_ID numbers. The AAPM research database was queried to produce an analysis of trends and demographics in research funding dating from 2002 to 2015. A total of 566 PI_ID numbers were matched to AAPM members. False-positive and -negative rates were respectively 4% (95% CI: 1-10%, N = 100) and 10% (95% CI: 5-18%, N = 99). Based on analysis of the AAPM research database, in 2015 the NIH awarded $USD 110M to members of the AAPM. The four NIH institutes which historically awarded the most funding to AAPM members were the National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering, National Heart Lung and Blood Institute, and National Institute of Neurological Disorders and Stroke. In 2015, over 85% of the total NIH research funding awarded to AAPM members was via these institutes, representing 1.1% of their combined budget. In the same year, 2.0% of AAPM members received NIH funding for a total of $116M, which is lower than the historic mean of $120M (in 2015 USD). A database of NIH-funded research awarded to AAPM members has been developed and tested using a data mining approach, and a top-level analysis of funding trends has been performed. Current funding of AAPM members is lower than

  2. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research.

    Science.gov (United States)

    Post, Andrew; Kurc, Tahsin; Overcash, Marc; Cantrell, Dedra; Morris, Tim; Eckerson, Kristi; Tsui, Circe; Willey, Terry; Quyyumi, Arshed; Eapen, Danny; Umpierrez, Guillermo; Ziemer, David; Saltz, Joel

    2011-01-01

    In the CTSA era there is great interest in aggregating and comparing populations across institutions. These sites likely represent data differently in their clinical data warehouses and other databases. Clinical data warehouses frequently are structured in a generalized way that supports many constituencies. For research, there is a need to transform these heterogeneous data into a shared representation, and to perform categorization and interpretation to optimize the data representation for investigators. We are addressing this need by extending an existing temporal abstraction-based clinical database query system, PROTEMPA. The extended system allows specifying data types of interest in federated databases, extracting the data into a shared representation, transforming it through categorization and interpretation, and loading it into a registry database that can be refreshed. Such a registry's access control, data representation and query tools can be tailored to the needs of research while keeping local databases as the source of truth.

  3. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Until now,Meteorological and Environmental Research [ISSN: 2152 - 3940] has been included by CAS and CABI from 2010.CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  4. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Meteorological and Environmental Research [ISSN: 2152 -3940]has been included by CAS and CABI since 2010. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  5. Research in Mobile Database Query Optimization and Processing

    Directory of Open Access Journals (Sweden)

    Agustinus Borgy Waluyo

    2005-01-01

    Full Text Available The emergence of mobile computing provides the ability to access information at any time and place. However, as mobile computing environments have inherent factors like power, storage, asymmetric communication cost, and bandwidth limitations, efficient query processing and minimum query response time are definitely of great interest. This survey groups a variety of query optimization and processing mechanisms in mobile databases into two main categories, namely: (i query processing strategy, and (ii caching management strategy. Query processing includes both pull and push operations (broadcast mechanisms. We further classify push operation into on-demand broadcast and periodic broadcast. Push operation (on-demand broadcast relates to designing techniques that enable the server to accommodate multiple requests so that the request can be processed efficiently. Push operation (periodic broadcast corresponds to data dissemination strategies. In this scheme, several techniques to improve the query performance by broadcasting data to a population of mobile users are described. A caching management strategy defines a number of methods for maintaining cached data items in clients' local storage. This strategy considers critical caching issues such as caching granularity, caching coherence strategy and caching replacement policy. Finally, this survey concludes with several open issues relating to mobile query optimization and processing strategy.

  6. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Until now, Meteorological and Environmental Research [ISSN:2152-3940] has been included by CAS and CABI from 2010. CAS is a division of the American Chemical Society established in 1907, and is the most authoritative and comprehensive source for chemical information. It is praised as the key of world literature treasury of Chemistry and Chemical. CAS monitors, indexes, and abstracts the world's chemistry-related literature and patents, updates this information daily, and makes it accessible through state...

  7. Oral contraceptives and venous thromboembolic disease. Analyses of the UK General Practice Research Database and the UK Mediplus database.

    Science.gov (United States)

    Farmer, R D; Lawrenson, R A; Todd, J C; Williams, T J; MacRae, K

    1999-01-01

    The results of three independent studies of venous thromboembolic disease (VTE) and oral contraceptives are reviewed together with two further cohort/case-control studies which we conducted using the MediPlus and General Practice Research Database (GPRD) databases. These latter studies jointly involved 395 cases and uniquely examined the association between VTE and individual combined oral contraceptive (COC) formulations. The two studies yielded very similar results. Crude incidence rates for idiopathic VTE of 4.6 and 3.8 were found per 10,000 exposed woman-years (EWY), in the MediPlus and GPRD studies respectively. Incidence rates increased markedly with age, and in both databases the rates amongst users of levonorgestrel products were lower than those amongst users of desogestrel and gestodene products. A case fatality rate of 3% and a mortality rate of 10 per million EWY were estimated. Odds ratios (OR) were calculated for confounding variables and different COC formulations. Both database studies indicated an excess of current smokers and women with high body mass indices amongst cases. There were significantly more cases with asthma in the GPRD study and cases who had been using their COC for less than a year. No statistically significant differences between COC formulations were found in the analyses where controls were matched to cases by practice and year of birth in both the MediPlus and GPRD studies. In the GPRD study we also ran a study where controls were matched by practice and within 5 year age bands. In this study the OR were consistently higher for the newer or 'third generation' products than when controls were matched by year of birth. However only the acne formulation/OC containing cyproterone acetate and 35 microg ethinyloestradiol yielded a significant OR of 2.3. It may be concluded that improvements in prescribing are paramount as the results strongly indicate that overweight women and those who smoke are at a greater risk of VTE. Further

  8. The Pitfalls of Cyberspace and Electronic Database Research--Who Sells What to Whom for Which Audience?

    Science.gov (United States)

    Willey, Susan

    2000-01-01

    Raises questions about the validity and reliability of doing research online via the proliferation of academic databases. Finds different versions of the Lexis-Nexis database have differing search capabilities. Argues that dependence on database research findings means dependence on decisions made by a few people who design search engines and…

  9. A Chronostratigraphic Relational Database Ontology

    Science.gov (United States)

    Platon, E.; Gary, A.; Sikora, P.

    2005-12-01

    an integrated query system for the searching across GEON's biostratigraphy databases, as well as databases available in the public domain. Although creating an ontology directly from the existing database metadata would have been effective and straightforward, our effort was directed towards creating a more efficient representation of our database, as well as a general representation of the biostratigraphic domain.

  10. Atlantic Canada's energy research and development website and database

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    Petroleum Research Atlantic Canada maintains a website devoted to energy research and development in Atlantic Canada. The site can be viewed on the world wide web at www.energyresearch.ca. It includes a searchable database with information about researchers in Nova Scotia, their projects and published materials on issues related to hydrocarbons, alternative energy technologies, energy efficiency, climate change, environmental impacts and policy. The website also includes links to research funding agencies, external related databases and related energy organizations around the world. Nova Scotia-based users are invited to submit their academic, private or public research to the site. Before being uploaded into the database, a site administrator reviews and processes all new information. Users are asked to identify their areas of interest according to the following research categories: alternative or renewable energy technologies; climate change; coal; computer applications; economics; energy efficiency; environmental impacts; geology; geomatics; geophysics; health and safety; human factors; hydrocarbons; meteorology and oceanology (metocean) activities; petroleum operations in deep and shallow waters; policy; and power generation and supply. The database can be searched 5 ways according to topic, researchers, publication, projects or funding agency. refs., tabs., figs.

  11. Open window: when easily identifiable genomes and traits are in the public domain.

    Directory of Open Access Journals (Sweden)

    Misha Angrist

    Full Text Available "One can't be of an enquiring and experimental nature, and still be very sensible."--Charles Fort. As the costs of personal genetic testing "self-quantification" fall, publicly accessible databases housing people's genotypic and phenotypic information are gradually increasing in number and scope. The latest entrant is openSNP, which allows participants to upload their personal genetic/genomic and self-reported phenotypic data. I believe the emergence of such open repositories of human biological data is a natural reflection of inquisitive and digitally literate people's desires to make genomic and phenotypic information more easily available to a community beyond the research establishment. Such unfettered databases hold the promise of contributing mightily to science, science education and medicine. That said, in an age of increasingly widespread governmental and corporate surveillance, we would do well to be mindful that genomic DNA is uniquely identifying. Participants in open biological databases are engaged in a real-time experiment whose outcome is unknown.

  12. Appropriateness of the food-pics image database for experimental eating and appetite research with adolescents.

    Science.gov (United States)

    Jensen, Chad D; Duraccio, Kara M; Barnett, Kimberly A; Stevens, Kimberly S

    2016-12-01

    Research examining effects of visual food cues on appetite-related brain processes and eating behavior has proliferated. Recently investigators have developed food image databases for use across experimental studies examining appetite and eating behavior. The food-pics image database represents a standardized, freely available image library originally validated in a large sample primarily comprised of adults. The suitability of the images for use with adolescents has not been investigated. The aim of the present study was to evaluate the appropriateness of the food-pics image library for appetite and eating research with adolescents. Three hundred and seven adolescents (ages 12-17) provided ratings of recognizability, palatability, and desire to eat, for images from the food-pics database. Moreover, participants rated the caloric content (high vs. low) and healthiness (healthy vs. unhealthy) of each image. Adolescents rated approximately 75% of the food images as recognizable. Approximately 65% of recognizable images were correctly categorized as high vs. low calorie and 63% were correctly classified as healthy vs. unhealthy in 80% or more of image ratings. These results suggest that a smaller subset of the food-pics image database is appropriate for use with adolescents. With some modifications to included images, the food-pics image database appears to be appropriate for use in experimental appetite and eating-related research conducted with adolescents. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Development of a pseudo/anonymised primary care research database: Proof-of-concept study.

    Science.gov (United States)

    MacRury, Sandra; Finlayson, Jim; Hussey-Wilson, Susan; Holden, Samantha

    2016-06-01

    General practice records present a comprehensive source of data that could form a variety of anonymised or pseudonymised research databases to aid identification of potential research participants regardless of location. A proof-of-concept study was undertaken to extract data from general practice systems in 15 practices across the region to form pseudo and anonymised research data sets. Two feasibility studies and a disease surveillance study compared numbers of potential study participants and accuracy of disease prevalence, respectively. There was a marked reduction in screening time and increase in numbers of potential study participants identified with the research repository compared with conventional methods. Accurate disease prevalence was established and enhanced with the addition of selective text mining. This study confirms the potential for development of national anonymised research database from general practice records in addition to improving data collection for local or national audits and epidemiological projects.

  14. Moving to Google Cloud: Renovation of Global Borehole Temperature Database for Climate Research

    Science.gov (United States)

    Xiong, Y.; Huang, S.

    2013-12-01

    Borehole temperature comprises an independent archive of information on climate change which is complementary to the instrumental and other proxy climate records. With support from the international geothermal community, a global database of borehole temperatures has been constructed for the specific purpose of the study on climate change. Although this database has become an important data source in climate research, there are certain limitations partially because the framework of the existing borehole temperature database was hand-coded some twenty years ago. A database renovation work is now underway to take the advantages of the contemporary online database technologies. The major intended improvements include 1) dynamically linking a borehole site to Google Earth to allow for inspection of site specific geographical information; 2) dynamically linking an original key reference of a given borehole site to Google Scholar to allow for a complete list of related publications; and 3) enabling site selection and data download based on country, coordinate range, and contributor. There appears to be a good match between the enhancement requirements for this database and the functionalities of the newly released Google Fusion Tables application. Google Fusion Tables is a cloud-based service for data management, integration, and visualization. This experimental application can consolidate related online resources such as Google Earth, Google Scholar, and Google Drive for sharing and enriching an online database. It is user friendly, allowing users to apply filters and to further explore the internet for additional information regarding the selected data. The users also have ways to map, to chart, and to calculate on the selected data, and to download just the subset needed. The figure below is a snapshot of the database currently under Google Fusion Tables renovation. We invite contribution and feedback from the geothermal and climate research community to make the

  15. Development of a computational database for probabilistic safety assessment of nuclear research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Macedo, Vagner S.; Oliveira, Patricia S. Pagetti de; Andrade, Delvonei Alves de, E-mail: vagner.macedo@usp.br, E-mail: patricia@ipen.br, E-mail: delvonei@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The objective of this work is to describe the database being developed at IPEN - CNEN / SP for application in the Probabilistic Safety Assessment of nuclear research reactors. The database can be accessed by means of a computational program installed in the corporate computer network, named IPEN Intranet, and this access will be allowed only to professionals previously registered. Data updating, editing and searching tasks will be controlled by a system administrator according to IPEN Intranet security rules. The logical model and the physical structure of the database can be represented by an Entity Relationship Model, which is based on the operational routines performed by IPEN - CNEN / SP users. The web application designed for the management of the database is named PSADB. It is being developed with MySQL database software and PHP programming language is being used. Data stored in this database are divided into modules that refer to technical specifications, operating history, maintenance history and failure events associated with the main components of the nuclear facilities. (author)

  16. The Creative Commons. A Third Way between Public Domain and Community ?

    Directory of Open Access Journals (Sweden)

    Clément Bert-Erboul

    2016-04-01

    Full Text Available How have the Creative Commons’ ownership rules used by free websites like Wikipedia or Flickr and in 3D printer projects or in alternative kitchen gardens, been develo­ped? Internet users and technological experimentation communities rely heavily on these free tools, but the ideologies of the public domain and online communities that allowed their birth often remain obscure. In this article we used American legal doctri­ne, the scientific literature and specialized press archives. From these sources we analyzed the links between Copyright reforms and the institutionalization of the activity of free software developers, at the origin of Creative Commons licenses. The case of intangible goods property applied to tangibles goods shows how the community members and institutions legitimize their IT practices by means of several producers of norms, such as States or communities.

  17. Database as a Tool for Promoting Research Activities in the Classroom: An Example in Teaching Humanities.

    Science.gov (United States)

    Degl'Innocenti, Riccardo; Ferraris, Maria

    1988-01-01

    Describes Datamondo, an instructional package that introduces the use of a newspaper database in humanities teaching at the secondary level in Italy. The effectiveness of the package in developing basic linguistic skills and as a research tool is evaluated. (8 references) (Author/CLB)

  18. Data-Based Decision Making at the Policy, Research, and Practice Levels

    NARCIS (Netherlands)

    Schildkamp, Kim; Ebbeler, Johanna

    2015-01-01

    Data-based decision making (DBDM) can lead to school improvement. However, schools struggle with the implementation of DBDM. In this symposium, we will discuss research and the implementation of DBDM at the national and regional policy level and the classroom level. We will discuss policy issues aro

  19. Quality standards for real-world research. Focus on observational database studies of comparative effectiveness.

    Science.gov (United States)

    Roche, Nicolas; Reddel, Helen; Martin, Richard; Brusselle, Guy; Papi, Alberto; Thomas, Mike; Postma, Dirjke; Thomas, Vicky; Rand, Cynthia; Chisholm, Alison; Price, David

    2014-02-01

    Real-world research can use observational or clinical trial designs, in both cases putting emphasis on high external validity, to complement the classical efficacy randomized controlled trials (RCTs) with high internal validity. Real-world research is made necessary by the variety of factors that can play an important a role in modulating effectiveness in real life but are often tightly controlled in RCTs, such as comorbidities and concomitant treatments, adherence, inhalation technique, access to care, strength of doctor-caregiver communication, and socio-economic and other organizational factors. Real-world studies belong to two main categories: pragmatic trials and observational studies, which can be prospective or retrospective. Focusing on comparative database observational studies, the process aimed at ensuring high-quality research can be divided into three parts: preparation of research, analyses and reporting, and discussion of results. Key points include a priori planning of data collection and analyses, identification of appropriate database(s), proper outcomes definition, study registration with commitment to publish, bias minimization through matching and adjustment processes accounting for potential confounders, and sensitivity analyses testing the robustness of results. When these conditions are met, observational database studies can reach a sufficient level of evidence to help create guidelines (i.e., clinical and regulatory decision-making).

  20. Opportunities for real-life respiratory research in Korea: The HIRA database and beyond

    NARCIS (Netherlands)

    Van Boven, Job F.M.; Rhee, Chin-Kook; Park, Hae-Yun; Yoo, Kwang H.; Kim, Dong-Kyu; Soriano, Joan; Ming, Simon Wan Yau; Price, David; Park, Hae Sim

    2016-01-01

    Background: To date, most real-life respiratory research has been conducted using databases from Europe and North America. However, over half of the World population suffering from asthma or chronic obstructive pulmonary disease (COPD) are living outside these areas, limiting generalizability of

  1. Current trends and new challenges of databases and web applications for systems driven biological research

    Directory of Open Access Journals (Sweden)

    Pradeep Kumar eSreenivasaiah

    2010-12-01

    Full Text Available Dynamic and rapidly evolving nature of systems driven research imposes special requirements on the technology, approach, design and architecture of computational infrastructure including database and web application. Several solutions have been proposed to meet the expectations and novel methods have been developed to address the persisting problems of data integration. It is important for researchers to understand different technologies and approaches. Having familiarized with the pros and cons of the existing technologies, researchers can exploit its capabilities to the maximum potential for integrating data. In this review we discuss the architecture, design and key technologies underlying some of the prominent databases (DBs and web applications. We will mention their roles in integration of biological data and investigate some of the emerging design concepts and computational technologies that are likely to have a key role in the future of systems driven biomedical research.

  2. Comparison of CINAHL, EMBASE, and MEDLINE databases for the nurse researcher.

    Science.gov (United States)

    Burnham, J; Shearer, B

    1993-01-01

    The purpose of this research was to determine which of three databases, CINAHL, EMBASE or MEDLINE, should be accessed when researching nursing topics. The three databases were searched for citations on topics selected by three nurse researchers and the results were compared. For the search of nursing care literature on a medical condition, it was helpful to search both CINAHL and MEDLINE. CINAHL provided the majority of relevant articles for the second search, on computers and privacy, but inclusion of MEDLINE and EMBASE enhanced retrieval somewhat. The search on substance abuse in pregnancy, not restricted to nursing literature, retrieved better results when searching both MEDLINE and EMBASE. Due to the nature and distribution of the nursing literature, it is especially important for the searcher to understand and respond to the focus of the researcher.

  3. [Relevance of design and structure of data-bases in research].

    Science.gov (United States)

    Sevillano García, M D

    2004-09-01

    Research studies require a methodological frame providing concepts and approach procedures. The so-called scientific method encompasses systematic data collection and problem solving notions. Epidemiology and statistics are essential disciplines in this process. The goal of this course is to provide knowledge for design of databases, with special attention to the definition of variables and to measurement scales. A small database on headache is made using fictitious information. A questionnaire designed for this purpose is used as a foundation. Finally, we present a graphic design on the percentage distribution of the variable gender, as an example of the summary statistics.

  4. MouldingSandDB – a modern database storing moulding sands properties research results

    Directory of Open Access Journals (Sweden)

    J. Jakubski

    2011-01-01

    Full Text Available The complexity of foundry processes requires the use of modern, advanced IT tools for optimization, storage and analysis of t echnicaldata. Properties of moulding and core sands that are collected in research laboratories, manufacturers, and finally in the foundries, are not in use later on. It seems important to create a database that will allow to use the results stored, along with the possibility of searching according to set criteria, adjusted to casting practice. This paper presents part of the database named „MouldingSandDB”, which allows to collect and search data for synthetic moulding sands.

  5. DOG-SPOT database for comprehensive management of dog genetic research data

    Directory of Open Access Journals (Sweden)

    Sutter Nathan B

    2010-12-01

    Full Text Available Abstract Research laboratories studying the genetics of companion animals have no database tools specifically designed to aid in the management of the many kinds of data that are generated, stored and analyzed. We have developed a relational database, "DOG-SPOT," to provide such a tool. Implemented in MS-Access, the database is easy to extend or customize to suit a lab's particular needs. With DOG-SPOT a lab can manage data relating to dogs, breeds, samples, biomaterials, phenotypes, owners, communications, amplicons, sequences, markers, genotypes and personnel. Such an integrated data structure helps ensure high quality data entry and makes it easy to track physical stocks of biomaterials and oligonucleotides.

  6. A guide for medical information searches of bibliographic databases - psychiatric research as an example.

    Science.gov (United States)

    Löhönen, Johanna; Isohanni, Matti; Nieminen, Pentti; Miettunen, Jouko

    2009-09-01

    Information overload, demanding work with strict time limits, and the extensive number of medical bibliographic databases and other research sources all underline the importance of being able to search for up-to-date information effectively. Medical journals play a key role in providing access to the latest information in medicine and health and bibliographic databases play an important role in accessing them. This paper sheds light on the role of the information search process and discusses how to approach key medical bibliographic databases and information sources, using the field of psychiatry as an example. Because of an increasing amount of information, the constant renewal within the discipline and a variety of services available, those seeking information must precisely define what kind of information they are looking for and from which sources the information needed may be found.

  7. GDR (Genome Database for Rosaceae: integrated web resources for Rosaceae genomics and genetics research

    Directory of Open Access Journals (Sweden)

    Ficklin Stephen

    2004-09-01

    Full Text Available Abstract Background Peach is being developed as a model organism for Rosaceae, an economically important family that includes fruits and ornamental plants such as apple, pear, strawberry, cherry, almond and rose. The genomics and genetics data of peach can play a significant role in the gene discovery and the genetic understanding of related species. The effective utilization of these peach resources, however, requires the development of an integrated and centralized database with associated analysis tools. Description The Genome Database for Rosaceae (GDR is a curated and integrated web-based relational database. GDR contains comprehensive data of the genetically anchored peach physical map, an annotated peach EST database, Rosaceae maps and markers and all publicly available Rosaceae sequences. Annotations of ESTs include contig assembly, putative function, simple sequence repeats, and anchored position to the peach physical map where applicable. Our integrated map viewer provides graphical interface to the genetic, transcriptome and physical mapping information. ESTs, BACs and markers can be queried by various categories and the search result sites are linked to the integrated map viewer or to the WebFPC physical map sites. In addition to browsing and querying the database, users can compare their sequences with the annotated GDR sequences via a dedicated sequence similarity server running either the BLAST or FASTA algorithm. To demonstrate the utility of the integrated and fully annotated database and analysis tools, we describe a case study where we anchored Rosaceae sequences to the peach physical and genetic map by sequence similarity. Conclusions The GDR has been initiated to meet the major deficiency in Rosaceae genomics and genetics research, namely a centralized web database and bioinformatics tools for data storage, analysis and exchange. GDR can be accessed at http://www.genome.clemson.edu/gdr/.

  8. Astronomy Education Research Observations from the iSTAR international Study of Astronomical Reasoning Database

    Science.gov (United States)

    Tatge, C. B.; Slater, S. J.; Slater, T. F.; Schleigh, S.; McKinnon, D.

    2016-12-01

    Historically, an important part of the scientific research cycle is to situate any research project within the landscape of the existing scientific literature. In the field of discipline-based astronomy education research, grappling with the existing literature base has proven difficult because of the difficulty in obtaining research reports from around the world, particularly early ones. In order to better survey and efficiently utilize the wide and fractured range and domain of astronomy education research methods and results, the iSTAR international Study of Astronomical Reasoning database project was initiated. The project aims to host a living, online repository of dissertations, theses, journal articles, and grey literature resources to serve the world's discipline-based astronomy education research community. The first domain of research artifacts ingested into the iSTAR database were doctoral dissertations. To the authors' great surprise, nearly 300 astronomy education research dissertations were found from the last 100-years. Few, if any, of the literature reviews from recent astronomy education dissertations surveyed even come close to summarizing this many dissertations, most of which have not been published in traditional journals, as re-publishing one's dissertation research as a journal article was not a widespread custom in the education research community until recently. A survey of the iSTAR database dissertations reveals that the vast majority of work has been largely quantitative in nature until the last decade. We also observe that modern-era astronomy education research writings reaches as far back as 1923 and that the majority of dissertations come from the same eight institutions. Moreover, most of the astronomy education research work has been done covering learners' grasp of broad knowledge of astronomy rather than delving into specific learning targets, which has been more in vogue during the last two decades. The surprisingly wide breadth

  9. MIPS PlantsDB: a database framework for comparative plant genome research.

    Science.gov (United States)

    Nussbaumer, Thomas; Martis, Mihaela M; Roessner, Stephan K; Pfeifer, Matthias; Bader, Kai C; Sharma, Sapna; Gundlach, Heidrun; Spannagl, Manuel

    2013-01-01

    The rapidly increasing amount of plant genome (sequence) data enables powerful comparative analyses and integrative approaches and also requires structured and comprehensive information resources. Databases are needed for both model and crop plant organisms and both intuitive search/browse views and comparative genomics tools should communicate the data to researchers and help them interpret it. MIPS PlantsDB (http://mips.helmholtz-muenchen.de/plant/genomes.jsp) was initially described in NAR in 2007 [Spannagl,M., Noubibou,O., Haase,D., Yang,L., Gundlach,H., Hindemitt, T., Klee,K., Haberer,G., Schoof,H. and Mayer,K.F. (2007) MIPSPlantsDB-plant database resource for integrative and comparative plant genome research. Nucleic Acids Res., 35, D834-D840] and was set up from the start to provide data and information resources for individual plant species as well as a framework for integrative and comparative plant genome research. PlantsDB comprises database instances for tomato, Medicago, Arabidopsis, Brachypodium, Sorghum, maize, rice, barley and wheat. Building up on that, state-of-the-art comparative genomics tools such as CrowsNest are integrated to visualize and investigate syntenic relationships between monocot genomes. Results from novel genome analysis strategies targeting the complex and repetitive genomes of triticeae species (wheat and barley) are provided and cross-linked with model species. The MIPS Repeat Element Database (mips-REdat) and Catalog (mips-REcat) as well as tight connections to other databases, e.g. via web services, are further important components of PlantsDB.

  10. Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis

    Directory of Open Access Journals (Sweden)

    Xiao Peng

    2004-02-01

    Full Text Available Abstract Background Public SNP databases are frequently used to choose SNPs for candidate genes in the association and linkage studies of complex disorders. However, their utility for such studies of diseases with ethnic-dependent background has never been evaluated. Results To estimate the accuracy and completeness of SNP public databases, we analyzed the allele frequencies of 41 SNPs in 10 candidate genes for obesity and/or osteoporosis in a large American-Caucasian sample (1,873 individuals from 405 nuclear families by PCR-invader assay. We compared our results with those from the databases and other published studies. Of the 41 SNPs, 8 were monomorphic in our sample. Twelve were reported for the first time for Caucasians and the other 29 SNPs in our sample essentially confirmed the respective allele frequencies for Caucasians in the databases and previous studies. The comparison of our data with other ethnic groups showed significant differentiation between the three major world ethnic groups at some SNPs (Caucasians and Africans differed at 3 of the 18 shared SNPs, and Caucasians and Asians differed at 13 of the 22 shared SNPs. This genetic differentiation may have an important implication for studying the well-known ethnic differences in the prevalence of obesity and osteoporosis, and complex disorders in general. Conclusion A comparative analysis of the SNP data of the candidate genes obtained in the present study, as well as those retrieved from the public domain, suggests that the databases may currently have serious limitations for studying complex disorders with an ethnic-dependent background due to the incomplete and uneven representation of the candidate SNPs in the databases for the major ethnic groups. This conclusion attests to the imperative necessity of large-scale and accurate characterization of these SNPs in different ethnic groups.

  11. Where in the genome are we? A cautionary tale of database use in genomics research.

    Directory of Open Access Journals (Sweden)

    Laura Kelly eVaughan

    2013-03-01

    Full Text Available With the advent of high throughput data genomic technologies the volume of available data is now staggering. In addition databases that provide resources to annotate, translate and connect biological data have grown exponentially in content and use. The availability of such data emphasizes the importance of bioinformatics and computational biology in genomics research and has led to the development of thousands of tools to integrate and utilize these resources. When utilizing such resources, the principles of reproducible research are often overlooked. In this manuscript we provide selected case studies illustrating issues that may arise while working with genes and genetic polymorphisms. These case studies illustrate potential sources of error which can be introduced if the practices of reproducible research are not employed and non-concurrent databases are used. We also show examples of a lack of transparency when these databases are concerned when using popular bioinformatics tools. These examples highlight that resources are constantly evolving, and in order to provide reproducible results, research should be aware of and connected to the correct release of the data, particularly when implementing computational tools.

  12. Insight: An ontology-based integrated database and analysis platform for epilepsy self-management research.

    Science.gov (United States)

    Sahoo, Satya S; Ramesh, Priya; Welter, Elisabeth; Bukach, Ashley; Valdez, Joshua; Tatsuoka, Curtis; Bamps, Yvan; Stoll, Shelley; Jobst, Barbara C; Sajatovic, Martha

    2016-10-01

    We present Insight as an integrated database and analysis platform for epilepsy self-management research as part of the national Managing Epilepsy Well Network. Insight is the only available informatics platform for accessing and analyzing integrated data from multiple epilepsy self-management research studies with several new data management features and user-friendly functionalities. The features of Insight include, (1) use of Common Data Elements defined by members of the research community and an epilepsy domain ontology for data integration and querying, (2) visualization tools to support real time exploration of data distribution across research studies, and (3) an interactive visual query interface for provenance-enabled research cohort identification. The Insight platform contains data from five completed epilepsy self-management research studies covering various categories of data, including depression, quality of life, seizure frequency, and socioeconomic information. The data represents over 400 participants with 7552 data points. The Insight data exploration and cohort identification query interface has been developed using Ruby on Rails Web technology and open source Web Ontology Language Application Programming Interface to support ontology-based reasoning. We have developed an efficient ontology management module that automatically updates the ontology mappings each time a new version of the Epilepsy and Seizure Ontology is released. The Insight platform features a Role-based Access Control module to authenticate and effectively manage user access to different research studies. User access to Insight is managed by the Managing Epilepsy Well Network database steering committee consisting of representatives of all current collaborating centers of the Managing Epilepsy Well Network. New research studies are being continuously added to the Insight database and the size as well as the unique coverage of the dataset allows investigators to conduct

  13. Fast resolution of the neutron diffusion equation through public domain Ode codes

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, V.M.; Vidal, V.; Garayoa, J. [Universidad Politecnica de Valencia, Departamento de Sistemas Informaticos, Valencia (Spain); Verdu, G. [Universidad Politecnica de Valencia, Departamento de Ingenieria Quimica y Nuclear, Valencia (Spain); Gomez, R. [I.E.S. de Tavernes Blanques, Valencia (Spain)

    2003-07-01

    The time-dependent neutron diffusion equation is a partial differential equation with source terms. The resolution method usually includes discretizing the spatial domain, obtaining a large system of linear, stiff ordinary differential equations (ODEs), whose resolution is computationally very expensive. Some standard techniques use a fixed time step to solve the ODE system. This can result in errors (if the time step is too large) or in long computing times (if the time step is too little). To speed up the resolution method, two well-known public domain codes have been selected: DASPK and FCVODE that are powerful codes for the resolution of large systems of stiff ODEs. These codes can estimate the error after each time step, and, depending on this estimation can decide which is the new time step and, possibly, which is the integration method to be used in the next step. With these mechanisms, it is possible to keep the overall error below the chosen tolerances, and, when the system behaves smoothly, to take large time steps increasing the execution speed. In this paper we address the use of the public domain codes DASPK and FCVODE for the resolution of the time-dependent neutron diffusion equation. The efficiency of these codes depends largely on the preconditioning of the big systems of linear equations that must be solved. Several pre-conditioners have been programmed and tested; it was found that the multigrid method is the best of the pre-conditioners tested. Also, it has been found that DASPK has performed better than FCVODE, being more robust for our problem.We can conclude that the use of specialized codes for solving large systems of ODEs can reduce drastically the computational work needed for the solution; and combining them with appropriate pre-conditioners, the reduction can be still more important. It has other crucial advantages, since it allows the user to specify the allowed error, which cannot be done in fixed step implementations; this, of course

  14. PDS: A Performance Database Server

    Directory of Open Access Journals (Sweden)

    Michael W. Berry

    1994-01-01

    Full Text Available The process of gathering, archiving, and distributing computer benchmark data is a cumbersome task usually performed by computer users and vendors with little coordination. Most important, there is no publicly available central depository of performance data for all ranges of machines from personal computers to supercomputers. We present an Internet-accessible performance database server (PDS that can be used to extract current benchmark data and literature. As an extension to the X-Windows-based user interface (Xnetlib to the Netlib archival system, PDS provides an on-line catalog of public domain computer benchmarks such as the LINPACK benchmark, Perfect benchmarks, and the NAS parallel benchmarks. PDS does not reformat or present the benchmark data in any way that conflicts with the original methodology of any particular benchmark; it is thereby devoid of any subjective interpretations of machine performance. We believe that all branches (research laboratories, academia, and industry of the general computing community can use this facility to archive performance metrics and make them readily available to the public. PDS can provide a more manageable approach to the development and support of a large dynamic database of published performance metrics.

  15. Research information needs on terrestrial vertebrate species of the interior Columbia basin and northern portions of the Klamath and Great Basins: a research, development, and application database.

    Science.gov (United States)

    Bruce G. Marcot

    1997-01-01

    Research information needs on selected invertebrates and all vertebrates of the interior Columbia River basin and adjacent areas in the United States were collected into a research, development, and application database as part of the Interior Columbia Basin Ecosystem Management Project. The database includes 482 potential research study topics on 232 individual...

  16. Product- and Process Units in the CRITT Translation Process Research Database

    DEFF Research Database (Denmark)

    Carl, Michael

    The first version of the "Translation Process Research Database" (TPR DB v1.0) was released In August 2012, containing logging data of more than 400 translation and text production sessions. The current version of the TPR DB, (v1.4), contains data from more than 940 sessions, which represents more...... than 300 hours of text production. The database provides the raw logging data, as well as Tables of pre-processed product- and processing units. The TPR-DB includes various types of simple and composed product and process units that are intended to support the analysis and modelling of human text...... reception, production, and translation processes. In this talk I describe some of the functions and features of the TPR-DB v1.4, and how they can be deployed in empirical human translation process research....

  17. Development of the Database for Environmental Sound Research and Application (DESRA: Design, Functionality, and Retrieval Considerations

    Directory of Open Access Journals (Sweden)

    Brian Gygi

    2010-01-01

    Full Text Available Theoretical and applied environmental sounds research is gaining prominence but progress has been hampered by the lack of a comprehensive, high quality, accessible database of environmental sounds. An ongoing project to develop such a resource is described, which is based upon experimental evidence as to the way we listen to sounds in the world. The database will include a large number of sounds produced by different sound sources, with a thorough background for each sound file, including experimentally obtained perceptual data. In this way DESRA can contain a wide variety of acoustic, contextual, semantic, and behavioral information related to an individual sound. It will be accessible on the Internet and will be useful to researchers, engineers, sound designers, and musicians.

  18. Building a recruitment database for asthma trials: a conceptual framework for the creation of the UK Database of Asthma Research Volunteers.

    Science.gov (United States)

    Nwaru, Bright I; Soyiri, Ireneous N; Simpson, Colin R; Griffiths, Chris; Sheikh, Aziz

    2016-05-26

    Randomised clinical trials are the 'gold standard' for evaluating the effectiveness of healthcare interventions. However, successful recruitment of participants remains a key challenge for many trialists. In this paper, we present a conceptual framework for creating a digital, population-based database for the recruitment of asthma patients into future asthma trials in the UK. Having set up the database, the goal is to then make it available to support investigators planning asthma clinical trials. The UK Database of Asthma Research Volunteers will comprise a web-based front-end that interactively allows participant registration, and a back-end that houses the database containing participants' key relevant data. The database will be hosted and maintained at a secure server at the Asthma UK Centre for Applied Research based at The University of Edinburgh. Using a range of invitation strategies, key demographic and clinical data will be collected from those pre-consenting to consider participation in clinical trials. These data will, with consent, in due course, be linkable to other healthcare, social, economic, and genetic datasets. To use the database, asthma investigators will send their eligibility criteria for participant recruitment; eligible participants will then be informed about the new trial and asked if they wish to participate. A steering committee will oversee the running of the database, including approval of usage access. Novel communication strategies will be utilised to engage participants who are recruited into the database in order to avoid attrition as a result of waiting time to participation in a suitable trial, and to minimise the risk of their being approached when already enrolled in a trial. The value of this database will be whether it proves useful and usable to researchers in facilitating recruitment into clinical trials on asthma and whether patient privacy and data security are protected in meeting this aim. Successful recruitment is

  19. Conference Proceedings: “Down Syndrome: National Conference on Patient Registries, Research Databases, and Biobanks”

    OpenAIRE

    Oster-Granite, Mary Lou; Parisi, Melissa A.; Abbeduto, Leonard; Berlin, Dorit S.; Bodine, Cathy; Bynum, Dana; Capone, George; Collier, Elaine; Hall, Dan; Kaeser, Lisa; Kaufmann, Petra; Krischer, Jeffrey; Livingston, Michelle; McCabe, Linda L.; Pace, Jill

    2011-01-01

    A December 2010 meeting, “Down Syndrome: National Conference on Patient Registries, Research Databases, and Biobanks,” was jointly sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) at the National Institutes of Health (NIH) in Bethesda, MD, and the Global Down Syndrome Foundation (GDSF)/Linda Crnic Institute for Down Syndrome based in Denver, CO. Approximately 70 attendees and organizers from various advocacy groups, federal agencies (Cen...

  20. Genomics and Public Health Research: Can the State Allow Access to Genomic Databases?

    Directory of Open Access Journals (Sweden)

    M Stanton Jean

    2012-04-01

    Full Text Available Because many diseases are multifactorial disorders,the scientific progress in genomics and genetics should be taken into consideration in public health research. In this context, genomic databases will constitute an important source of information. Consequently, it is important to identify and characterize the State's role and authority on matters related to public health,in order to verify whether it has access to such databases while engaging in public health genomic research. We first consider the evolution of the concept of public health, as well as its core functions, using a comparative approach (e.g. WHO, PAHO, CDC and the Canadian province of Quebec. Following an analysis of relevant Quebec legislation, the precautionary principle is examined as a possible avenue to justify State access to and use of genomic databases for research purposes. Finally, we consider the Influenza pandemic plans developed by WHO, Canada, and Quebec,as examples of key tools framing public health decision-making process.We observed that State powers in public health, are not,in Quebec,well adapted to the expansion of genomics research.We propose that the scope of the concept of research in public health should be clear and include the following characteristics:a commitment to the health and well-being of the population and to their determinants; the inclusion of both applied research and basic research; and, an appropriate model of governance (authorization, follow-up,consent, etc..We also suggest that the strategic approach version of the precautionary principle could guide collective choices in these matters.

  1. CmMDb: a versatile database for Cucumis melo microsatellite markers and other horticulture crop research.

    Science.gov (United States)

    Bhawna; Chaduvula, Pavan K; Bonthala, Venkata S; Manjusha, Verma; Siddiq, Ebrahimali A; Polumetla, Ananda K; Prasad, Gajula M N V

    2015-01-01

    Cucumis melo L. that belongs to Cucurbitaceae family ranks among one of the highest valued horticulture crops being cultivated across the globe. Besides its economical and medicinal importance, Cucumis melo L. is a valuable resource and model system for the evolutionary studies of cucurbit family. However, very limited numbers of molecular markers were reported for Cucumis melo L. so far that limits the pace of functional genomic research in melon and other similar horticulture crops. We developed the first whole genome based microsatellite DNA marker database of Cucumis melo L. and comprehensive web resource that aids in variety identification and physical mapping of Cucurbitaceae family. The Cucumis melo L. microsatellite database (CmMDb: http://65.181.125.102/cmmdb2/index.html) encompasses 39,072 SSR markers along with its motif repeat, motif length, motif sequence, marker ID, motif type and chromosomal locations. The database is featured with novel automated primer designing facility to meet the needs of wet lab researchers. CmMDb is a freely available web resource that facilitates the researchers to select the most appropriate markers for marker-assisted selection in melons and to improve breeding strategies.

  2. The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2016 Update on Research.

    Science.gov (United States)

    Jacobs, Marshall L; Jacobs, Jeffrey P; Pasquali, Sara K; Hill, Kevin D; Hornik, Christoph; O'Brien, Sean M; Shahian, David M; Habib, Robert H; Edwards, Fred H

    2016-09-01

    The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD) is the largest congenital and pediatric cardiac surgical clinical data registry in the world. With more than 400,000 total operations from nearly all centers performing pediatric and congenital heart operations in North America, the STS CHSD is an unparalleled platform for clinical investigation, outcomes research, and quality improvement activities in this subspecialty. In 2015, several major original publications reported analyses of data in the CHSD pertaining to specific diagnostic and procedural groups, age-defined cohorts, or the entire population of patients in the database. Additional publications reported the most recent development, evaluation, and application of metrics for quality measurement and reporting of pediatric and congenital heart operation outcomes. This use of the STS CHSD for outcomes research and for quality measurement continues to expand as database participation and the available wealth of data in it continue to grow. This article reviews outcomes research and quality improvement articles published in 2015 based on STS CHSD data.

  3. The international river interface cooperative: Public domain flow and morphodynamics software for education and applications

    Science.gov (United States)

    Nelson, Jonathan M.; Shimizu, Yasuyuki; Abe, Takaaki; Asahi, Kazutake; Gamou, Mineyuki; Inoue, Takuya; Iwasaki, Toshiki; Kakinuma, Takaharu; Kawamura, Satomi; Kimura, Ichiro; Kyuka, Tomoko; McDonald, Richard R.; Nabi, Mohamed; Nakatsugawa, Makoto; Simões, Francisco R.; Takebayashi, Hiroshi; Watanabe, Yasunori

    2016-07-01

    This paper describes a new, public-domain interface for modeling flow, sediment transport and morphodynamics in rivers and other geophysical flows. The interface is named after the International River Interface Cooperative (iRIC), the group that constructed the interface and many of the current solvers included in iRIC. The interface is entirely free to any user and currently houses thirteen models ranging from simple one-dimensional models through three-dimensional large-eddy simulation models. Solvers are only loosely coupled to the interface so it is straightforward to modify existing solvers or to introduce other solvers into the system. Six of the most widely-used solvers are described in detail including example calculations to serve as an aid for users choosing what approach might be most appropriate for their own applications. The example calculations range from practical computations of bed evolution in natural rivers to highly detailed predictions of the development of small-scale bedforms on an initially flat bed. The remaining solvers are also briefly described. Although the focus of most solvers is coupled flow and morphodynamics, several of the solvers are also specifically aimed at providing flood inundation predictions over large spatial domains. Potential users can download the application, solvers, manuals, and educational materials including detailed tutorials at www.-i-ric.org. The iRIC development group encourages scientists and engineers to use the tool and to consider adding their own methods to the iRIC suite of tools.

  4. Assessing water availability over peninsular Malaysia using public domain satellite data products

    Science.gov (United States)

    Ali, M. I.; Hashim, M.; Zin, H. S. M.

    2014-02-01

    Water availability monitoring is an essential task for water resource sustainability and security. In this paper, the assessment of satellite remote sensing technique for determining water availability is reported. The water-balance analysis is used to compute the spatio-temporal water availability with main inputs; the precipitation and actual evapotranspiration rate (AET), both fully derived from public-domain satellite products of Tropical Rainfall Measurement Mission (TRMM) and MODIS, respectively. Both these satellite products were first subjected to calibration to suit corresponding selected local precipitation and AET samples. Multi-temporal data sets acquired 2000-2010 were used in this study. The results of study, indicated strong agreement of monthly water availability with the basin flow rate (r2 = 0.5, p < 0.001). Similar agreements were also noted between the estimated annual average water availability with the in-situ measurement. It is therefore concluded that the method devised in this study provide a new alternative for water availability mapping over large area, hence offers the only timely and cost-effective method apart from providing comprehensive spatio-temporal patterns, crucial in water resource planning to ensure water security.

  5. Public domain small-area cancer incidence data for New York State, 2005-2009

    Directory of Open Access Journals (Sweden)

    Francis P. Boscoe

    2016-04-01

    Full Text Available There has long been a demand for cancer incidence data at a fine geographic resolution for use in etiologic hypothesis generation and testing, methodological evaluation and teaching. In this paper we describe a public domain dataset containing data for 23 anatomic sites of cancer diagnosed in New York State, USA between 2005 and 2009 at the census block group level. The dataset includes 524,503 tumours distributed across 13,823 block groups with an average population of about 1400. In addition, the data have been linked with race/ethnicity and with socioeconomic indicators such as income, educational attainment and language proficiency. We demonstrate the application of the dataset by confirming two well-established relationships: that between breast cancer and median household income and that between stomach cancer and Asian race. We foresee that this dataset will serve as the basis for a wide range of spatial analyses and as a benchmark for evaluating spatial methods in the future.

  6. Assessment of current cybersecurity practices in the public domain : cyber indications and warnings domain.

    Energy Technology Data Exchange (ETDEWEB)

    Hamlet, Jason R.; Keliiaa, Curtis M.

    2010-09-01

    This report assesses current public domain cyber security practices with respect to cyber indications and warnings. It describes cybersecurity industry and government activities, including cybersecurity tools, methods, practices, and international and government-wide initiatives known to be impacting current practice. Of particular note are the U.S. Government's Trusted Internet Connection (TIC) and 'Einstein' programs, which are serving to consolidate the Government's internet access points and to provide some capability to monitor and mitigate cyber attacks. Next, this report catalogs activities undertaken by various industry and government entities. In addition, it assesses the benchmarks of HPC capability and other HPC attributes that may lend themselves to assist in the solution of this problem. This report draws few conclusions, as it is intended to assess current practice in preparation for future work, however, no explicit references to HPC usage for the purpose of analyzing cyber infrastructure in near-real-time were found in the current practice. This report and a related SAND2010-4766 National Cyber Defense High Performance Computing and Analysis: Concepts, Planning and Roadmap report are intended to provoke discussion throughout a broad audience about developing a cohesive HPC centric solution to wide-area cybersecurity problems.

  7. Preserving Madagascar's Natural Heritage: The Importance of Keeping the Island's Vertebrate Fossils in the Public Domain

    Directory of Open Access Journals (Sweden)

    Karen E. Samonds

    2006-12-01

    Full Text Available The origin of Madagascar’s highly endemic vertebrate fauna remains one of the great unsolved mysteries of natural history. From what landmasses did the basal stocks of this unique and imbalanced fauna come? When and how did the ancestral populations arrive on the island? How rapidly did they diversify, and why? The most direct means of addressing these questions, and other enigmas concerning the evolutionary and biogeographic history of Madagascar’s vertebrate fauna, is through discovery of fossils from a sequence of well-dated geological horizons. Many fossils relevant to these queries have been discovered by paleontologists in recent years ... but many more are being lost to commercial enterprises, both foreign and domestic, that have little or no regard for the scientific significance of fossils. The objectives of this essay are to 1 provide an overview of Madagascar’s vertebrate fossil record and its importance, 2 raise awareness concerning the illegal collection, exportation, and sale of vertebrate fossils, and 3 stress the importance of keeping vertebrate fossils from the island in the public domain. In light of these issues, we underscore the necessity for development of adequate repositories and support infrastructure in Madagascar to safeguard and display the country’s vertebrate fossil collections; doing so would ensure the preservation and appreciation of Madagascar’s rich natural heritage for future generations of scientists and Malagasy citizens alike.

  8. The international river interface cooperative: Public domain flow and morphodynamics software for education and applications

    Science.gov (United States)

    Nelson, Jonathan M.; Shimizu, Yasuyuki; Abe, Takaaki; Asahi, Kazutake; Gamou, Mineyuki; Inoue, Takuya; Iwasaki, Toshiki; Kakinuma, Takaharu; Kawamura, Satomi; Kimura, Ichiro; Kyuka, Tomoko; McDonald, Richard R.; Nabi, Mohamed; Nakatsugawa, Makoto; Simoes, Francisco J.; Takebayashi, Hiroshi; Watanabe, Yasunori

    2016-01-01

    This paper describes a new, public-domain interface for modeling flow, sediment transport and morphodynamics in rivers and other geophysical flows. The interface is named after the International River Interface Cooperative (iRIC), the group that constructed the interface and many of the current solvers included in iRIC. The interface is entirely free to any user and currently houses thirteen models ranging from simple one-dimensional models through three-dimensional large-eddy simulation models. Solvers are only loosely coupled to the interface so it is straightforward to modify existing solvers or to introduce other solvers into the system. Six of the most widely-used solvers are described in detail including example calculations to serve as an aid for users choosing what approach might be most appropriate for their own applications. The example calculations range from practical computations of bed evolution in natural rivers to highly detailed predictions of the development of small-scale bedforms on an initially flat bed. The remaining solvers are also briefly described. Although the focus of most solvers is coupled flow and morphodynamics, several of the solvers are also specifically aimed at providing flood inundation predictions over large spatial domains. Potential users can download the application, solvers, manuals, and educational materials including detailed tutorials at www.-i-ric.org. The iRIC development group encourages scientists and engineers to use the tool and to consider adding their own methods to the iRIC suite of tools.

  9. A simple technique for morphological measurement of cerebral arterial circle variations using public domain software (Osiris).

    Science.gov (United States)

    Ansari, Saeed; Dadmehr, Majid; Eftekhar, Behzad; McConnell, Douglas J; Ganji, Sarah; Azari, Hassan; Kamali-Ardakani, Shahab; Hoh, Brian L; Mocco, J

    2011-12-01

    This article describes a straightforward method to measure the dimensions and identify morphological variations in the cerebral arterial circle using the general-purpose software program Osiris. This user-friendly and portable program displays, manipulates, and analyzes medical digital images, and it has the capability to determine morphometric properties of selected blood vessels (or other anatomical structures) in humans and animals. To ascertain morphometric variations in the cerebral arterial circle, 132 brains of recently deceased fetuses, infants, and adults were dissected. The dissection procedure was first digitized, and then the dimensions were measured with Osiris software. Measurements of each vessel's length and external diameters were used to identify and classify morphological variations in the cerebral arterial circle. The most commonly observed anatomical variations were uni- and bilateral hypoplasia of the posterior communicating artery. This study demonstrates that public domain software can be used to measure and classify cerebral arterial circle vessels. This method could be extended to examine other anatomical regions or to study other animals. Additionally, knowledge of variations within the circle could be applied clinically to enhance diagnostic and treatment specificity.

  10. APD3: the antimicrobial peptide database as a tool for research and education.

    Science.gov (United States)

    Wang, Guangshun; Li, Xia; Wang, Zhe

    2016-01-04

    The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3. This database currently focuses on natural antimicrobial peptides (AMPs) with defined sequence and activity. It includes a total of 2619 AMPs with 261 bacteriocins from bacteria, 4 AMPs from archaea, 7 from protists, 13 from fungi, 321 from plants and 1972 animal host defense peptides. The APD3 contains 2169 antibacterial, 172 antiviral, 105 anti-HIV, 959 antifungal, 80 antiparasitic and 185 anticancer peptides. Newly annotated are AMPs with antibiofilm, antimalarial, anti-protist, insecticidal, spermicidal, chemotactic, wound healing, antioxidant and protease inhibiting properties. We also describe other searchable annotations, including target pathogens, molecule-binding partners, post-translational modifications and animal models. Amino acid profiles or signatures of natural AMPs are important for peptide classification, prediction and design. Finally, we summarize various database applications in research and education.

  11. Database of osmoregulated proteins in mammalian cells.

    Science.gov (United States)

    Grady, Cameron R; Knepper, Mark A; Burg, Maurice B; Ferraris, Joan D

    2014-10-28

    Biological information, even in highly specialized fields, is increasing at a volume that no single investigator can assimilate. The existence of this vast knowledge base creates the need for specialized computer databases to store and selectively sort the information. We have developed a manually curated database of the effects of hypertonicity on target proteins. Effects include changes in mRNA abundance and protein abundance, activity, phosphorylation state, binding, and cellular compartment. The biological information used in this database was derived from three research approaches: transcriptomic, proteomic, and reductionist (hypothesis-driven). The data are presented in the form of grammatical triplets consisting of subject, verb phrase, and object. The purpose of this format is to allow the data to be read from left to right as an English sentence. It is readable either by humans or by computers using natural language processing algorithms. An example of a data entry reads "Hypertonicity increases activity of ABL1 in HEK293." This database was created to provide access to a wealth of information on the effects of hypertonicity in a format that can be selectively sorted. Published 2014. This article is a U.S. Government work and is in the public domain in the USA. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  12. Longitudinal research databases in medical education: facilitating the study of educational outcomes over time and across institutions.

    Science.gov (United States)

    Cook, David A; Andriole, Dorothy A; Durning, Steven J; Roberts, Nicole K; Triola, Marc M

    2010-08-01

    Many education research questions cannot be answered using participants from one institution or short periods of follow-up. In response to societal demands for accountability and evidence of effectiveness, new models of research must be developed to study the outcomes of educational activities. Following the 2007 Millennium Conference on Medical Education Research, organizers assigned a task force to explore the use of longitudinal databases in education research. This article summarizes the task force's findings. Similar to the Framingham studies in clinical medicine, longitudinal databases assemble prospectively collected information to retrospectively answer questions of interest. Many studies using such databases have been published. The task force identified three general approaches to database-type research. First, institutions can obtain identified information from existing sources, link it with school-specific information and other identified information, deidentify it, and merge it with similar information from other collaborating schools. Second, researchers can obtain from existing sources deidentified information on large samples and explore associations within this dataset. Third, investigators can design and implement databases to prospectively collect trainee information over time and across multiple institutions for the purpose of education research. Although costly, such comprehensive, purpose-built databases would ensure the availability of information needed to answer a variety of medical education research questions. Millennium Conference participants believed that stakeholders should explore the funding and development of such prospective databases. In the meantime, education researchers should use existing sources of individualized learner data to better understand how to develop competent, compassionate clinicians.

  13. Adjusting for COPD severity in database research: developing and validating an algorithm

    Directory of Open Access Journals (Sweden)

    Goossens LMA

    2011-12-01

    Full Text Available Lucas MA Goossens1, Christine L Baker2, Brigitta U Monz3, Kelly H Zou2, Maureen PMH Rutten-van Mölken11Institute for Medical Technology Assessment, Erasmus University, Rotterdam, The Netherlands; 2Pfizer Inc, New York City, NY, USA; 3Boehringer Ingelheim International GmbH, Ingelheim am Rhein, GermanyPurpose: When comparing chronic obstructive lung disease (COPD interventions in database research, it is important to adjust for severity. Global Initiative for Chronic Obstructive Lung Disease (GOLD guidelines grade severity according to lung function. Most databases lack data on lung function. Previous database research has approximated COPD severity using demographics and healthcare utilization. This study aims to derive an algorithm for COPD severity using baseline data from a large respiratory trial (UPLIFT.Methods: Partial proportional odds logit models were developed for probabilities of being in GOLD stages II, III and IV. Concordance between predicted and observed stage was assessed using kappa-statistics. Models were estimated in a random selection of 2/3 of patients and validated in the remainder. The analysis was repeated in a subsample with a balanced distribution across severity stages. Univariate associations of COPD severity with the covariates were tested as well.Results: More severe COPD was associated with being male and younger, having quit smoking, lower BMI, osteoporosis, hospitalizations, using certain medications, and oxygen. After adjusting for these variables, co-morbidities, previous healthcare resource use (eg, emergency room, hospitalizations and inhaled corticosteroids, xanthines, or mucolytics were no longer independently associated with COPD severity, although they were in univariate tests. The concordance was poor (kappa = 0.151 and only slightly better in the balanced sample (kappa = 0.215.Conclusion: COPD severity cannot be reliably predicted from demographics and healthcare use. This limitation should be

  14. Chess databases as a research vehicle in psychology: Modeling large data.

    Science.gov (United States)

    Vaci, Nemanja; Bilalić, Merim

    2016-09-01

    The game of chess has often been used for psychological investigations, particularly in cognitive science. The clear-cut rules and well-defined environment of chess provide a model for investigations of basic cognitive processes, such as perception, memory, and problem solving, while the precise rating system for the measurement of skill has enabled investigations of individual differences and expertise-related effects. In the present study, we focus on another appealing feature of chess-namely, the large archive databases associated with the game. The German national chess database presented in this study represents a fruitful ground for the investigation of multiple longitudinal research questions, since it collects the data of over 130,000 players and spans over 25 years. The German chess database collects the data of all players, including hobby players, and all tournaments played. This results in a rich and complete collection of the skill, age, and activity of the whole population of chess players in Germany. The database therefore complements the commonly used expertise approach in cognitive science by opening up new possibilities for the investigation of multiple factors that underlie expertise and skill acquisition. Since large datasets are not common in psychology, their introduction also raises the question of optimal and efficient statistical analysis. We offer the database for download and illustrate how it can be used by providing concrete examples and a step-by-step tutorial using different statistical analyses on a range of topics, including skill development over the lifetime, birth cohort effects, effects of activity and inactivity on skill, and gender differences.

  15. Fine-grained policy control in U.S. Army Research Laboratory (ARL) multimodal signatures database

    Science.gov (United States)

    Bennett, Kelly; Grueneberg, Keith; Wood, David; Calo, Seraphin

    2014-06-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) consists of a number of colocated relational databases representing a collection of data from various sensors. Role-based access to this data is granted to external organizations such as DoD contractors and other government agencies through a client Web portal. In the current MMSDB system, access control is only at the database and firewall level. In order to offer finer grained security, changes to existing user profile schemas and authentication mechanisms are usually needed. In this paper, we describe a software middleware architecture and implementation that allows fine-grained access control to the MMSDB at a dataset, table, and row level. Result sets from MMSDB queries issued in the client portal are filtered with the use of a policy enforcement proxy, with minimal changes to the existing client software and database. Before resulting data is returned to the client, policies are evaluated to determine if the user or role is authorized to access the data. Policies can be authored to filter data at the row, table or column level of a result set. The system uses various technologies developed in the International Technology Alliance in Network and Information Science (ITA) for policy-controlled information sharing and dissemination1. Use of the Policy Management Library provides a mechanism for the management and evaluation of policies to support finer grained access to the data in the MMSDB system. The GaianDB is a policy-enabled, federated database that acts as a proxy between the client application and the MMSDB system.

  16. Proving and therapeutic experiments in the HomBRex basic homeopathy research database.

    Science.gov (United States)

    Van Wijk, R; Albrecht, H

    2007-10-01

    The HomBRex database of basic research experiments on homeopathy indexes studies on biological systems including animal, human, plant, fungi and microbial organisms. Its objective is to index proving and therapeutic experiments on the Similia Principle and the role of dilution and succussion of substances in experimental biologic systems. The database was analyzed when it contained more than 1100 experiments in more than 900 original articles. The database provides information on 732 experiments using healthy human, animal and plant systems. These experiments were divided into 'ideal' model proving (475) and prophylactic (257) categories. It also includes 397 therapeutic experiments, in which an effect of a substance was tested in a diseased or disturbed system. A large number of substances were used, including high and low dilutions and potencies-191 substances in proving, 130 in prophylactic and 112 in therapeutic experiments. In general, basic research in homeopathy does not directly investigate the Similia Principle. We conclude, that from the overwhelming variety in organisms, diseased states, and substances, only a limited number of biological systems and states should be selected to study the Similia Principle.

  17. A database for reproducible manipulation research: CapriDB – Capture, Print, Innovate

    Directory of Open Access Journals (Sweden)

    Florian T. Pokorny

    2017-04-01

    Full Text Available We present a novel approach and database which combines the inexpensive generation of 3D object models via monocular or RGB-D camera images with 3D printing and a state of the art object tracking algorithm. Unlike recent efforts towards the creation of 3D object databases for robotics, our approach does not require expensive and controlled 3D scanning setups and aims to enable anyone with a camera to scan, print and track complex objects for manipulation research. The proposed approach results in detailed textured mesh models whose 3D printed replicas provide close approximations of the originals. A key motivation for utilizing 3D printed objects is the ability to precisely control and vary object properties such as the size, material properties and mass distribution in the 3D printing process to obtain reproducible conditions for robotic manipulation research. We present CapriDB – an extensible database resulting from this approach containing initially 40 textured and 3D printable mesh models together with tracking features to facilitate the adoption of the proposed approach.

  18. Research on Performance Evaluation of Biological Database based on Layered Queuing Network Model under the Cloud Computing Environment

    OpenAIRE

    Zhengbin Luo; Dongmei Sun

    2013-01-01

    To evaluate the performance of biological database based on layered queuing network model and under cloud computing environment is a premise, as well as an important step for biological database optimization. Based on predecessors’ researches concerning computer software and hardware performance evaluation under cloud environment, the study has further constructed a model system to evaluate the performance of biological database based on layered queuing network model and under cloud environme...

  19. Conference Proceedings: “Down Syndrome: National Conference on Patient Registries, Research Databases, and Biobanks”

    Science.gov (United States)

    Oster-Granite, Mary Lou; Parisi, Melissa A.; Abbeduto, Leonard; Berlin, Dorit S.; Bodine, Cathy; Bynum, Dana; Capone, George; Collier, Elaine; Hall, Dan; Kaeser, Lisa; Kaufmann, Petra; Krischer, Jeffrey; Livingston, Michelle; McCabe, Linda L.; Pace, Jill; Pfenninger, Karl; Rasmussen, Sonja A.; Reeves, Roger H.; Rubinstein, Yaffa; Sherman, Stephanie; Terry, Sharon F.; Whitten, Michelle Sie; Williams, Stephen; McCabe, Edward R.B.; Maddox, Yvonne T.

    2011-01-01

    A December 2010 meeting, “Down Syndrome: National Conference on Patient Registries, Research Databases, and Biobanks,” was jointly sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) at the National Institutes of Health (NIH) in Bethesda, MD, and the Global Down Syndrome Foundation (GDSF)/Linda Crnic Institute for Down Syndrome based in Denver, CO. Approximately 70 attendees and organizers from various advocacy groups, federal agencies (Centers for Disease Control and Prevention, and various NIH Institutes, Centers, and Offices), members of industry, clinicians, and researchers from various academic institutions were greeted by Drs. Yvonne Maddox, Deputy Director of NICHD, and Edward McCabe, Executive Director of the Linda Crnic Institute for Down Syndrome. They charged the participants to focus on the separate issues of contact registries, research databases, and biobanks through both podium presentations and breakout session discussions. Among the breakout groups for each of the major sessions, participants were asked to generate responses to questions posed by the organizers concerning these three research resources as they related to Down syndrome and then to report back to the group at large with a summary of their discussions. This report represents a synthesis of the discussions and suggested approaches formulated by the group as a whole. PMID:21835664

  20. The Traumatic Brain Injury Model Systems: a longitudinal database, research, collaboration and knowledge translation.

    Science.gov (United States)

    Hammond, F M; Malec, J F

    2010-12-01

    In 1988, the National Institute on Disability and Rehabilitation Research (NIDRR) launched the Traumatic Brain Injury Model Systems (TBIMS) program, creating the longest and largest longitudinal database on individuals with moderate-to-severe traumatic brain injury (TBI) available today. In addition to sustaining the longitudinal database, centers that successfully compete to be part of the TBIMS centers are also expected to complete local and collaborative research projects to further scientific knowledge about TBI. The research has focused on areas of the NIDRR Long Range Plan which emphasizes employment, health and function, technology for access and function, independent living and community integration, and other associated disability research areas. Centers compete for funded participation in the TBIMS on a 5-year cycle. Dissemination of scientific knowledge gained through the TBIMS is the responsibility of both individual centers and the TBIMS as a whole. This is accomplished through multiple venues that target a broad audience of those who need to receive the information and learn how to best apply it to practice. The sites produce many useful websites, manuals, publications and other materials to accomplish this translation of knowledge to practice.

  1. The Cancer Epidemiology Descriptive Cohort Database: A Tool to Support Population-Based Interdisciplinary Research.

    Science.gov (United States)

    Kennedy, Amy E; Khoury, Muin J; Ioannidis, John P A; Brotzman, Michelle; Miller, Amy; Lane, Crystal; Lai, Gabriel Y; Rogers, Scott D; Harvey, Chinonye; Elena, Joanne W; Seminara, Daniela

    2016-10-01

    We report on the establishment of a web-based Cancer Epidemiology Descriptive Cohort Database (CEDCD). The CEDCD's goals are to enhance awareness of resources, facilitate interdisciplinary research collaborations, and support existing cohorts for the study of cancer-related outcomes. Comprehensive descriptive data were collected from large cohorts established to study cancer as primary outcome using a newly developed questionnaire. These included an inventory of baseline and follow-up data, biospecimens, genomics, policies, and protocols. Additional descriptive data extracted from publicly available sources were also collected. This information was entered in a searchable and publicly accessible database. We summarized the descriptive data across cohorts and reported the characteristics of this resource. As of December 2015, the CEDCD includes data from 46 cohorts representing more than 6.5 million individuals (29% ethnic/racial minorities). Overall, 78% of the cohorts have collected blood at least once, 57% at multiple time points, and 46% collected tissue samples. Genotyping has been performed by 67% of the cohorts, while 46% have performed whole-genome or exome sequencing in subsets of enrolled individuals. Information on medical conditions other than cancer has been collected in more than 50% of the cohorts. More than 600,000 incident cancer cases and more than 40,000 prevalent cases are reported, with 24 cancer sites represented. The CEDCD assembles detailed descriptive information on a large number of cancer cohorts in a searchable database. Information from the CEDCD may assist the interdisciplinary research community by facilitating identification of well-established population resources and large-scale collaborative and integrative research. Cancer Epidemiol Biomarkers Prev; 25(10); 1392-401. ©2016 AACR. ©2016 American Association for Cancer Research.

  2. Construction of a bibliographic information database and development of retrieval system for research reports in nuclear science and technology (II)

    Energy Technology Data Exchange (ETDEWEB)

    Han, Duk Haeng; Kim, Tae Whan; Choi, Kwang; Yoo, An Na; Keum, Jong Yong; Kim, In Kwon [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-05-01

    The major goal of this project is to construct a bibliographic information database in nuclear engineering and to develop a prototype retrieval system. To give an easy access to microfiche research report, this project has accomplished the construction of microfiche research reports database and the development of retrieval system. The results of the project are as follows; 1. Microfiche research reports database was constructed by downloading from DOE Energy, NTIS, INIS. 2. The retrieval system was developed in host and web version using access point such as title, abstracts, keyword, report number. 6 tabs., 8 figs., 11 refs. (Author) .new.

  3. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    DEFF Research Database (Denmark)

    Jones, Roy; Wilkinson, David; Lopez, Oscar L;

    2011-01-01

    Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical...

  4. FmMDb: A Versatile Database of Foxtail Millet Markers for Millets and Bioenergy Grasses Research

    Science.gov (United States)

    Misra, Gopal; Prasad, Manoj

    2013-01-01

    The prominent attributes of foxtail millet (Setaria italica L.) including its small genome size, short life cycle, inbreeding nature, and phylogenetic proximity to various biofuel crops have made this crop an excellent model system to investigate various aspects of architectural, evolutionary and physiological significances in Panicoid bioenergy grasses. After release of its whole genome sequence, large-scale genomic resources in terms of molecular markers were generated for the improvement of both foxtail millet and its related species. Hence it is now essential to congregate, curate and make available these genomic resources for the benefit of researchers and breeders working towards crop improvement. In view of this, we have constructed the Foxtail millet Marker Database (FmMDb; http://www.nipgr.res.in/foxtail.html), a comprehensive online database for information retrieval, visualization and management of large-scale marker datasets with unrestricted public access. FmMDb is the first database which provides complete marker information to the plant science community attempting to produce elite cultivars of millet and bioenergy grass species, thus addressing global food insecurity. PMID:23951158

  5. YM500v3: a database for small RNA sequencing in human cancer research

    Science.gov (United States)

    Chung, I-Fang; Chang, Shing-Jyh; Chen, Chen-Yang; Liu, Shu-Hsuan; Li, Chia-Yang; Chan, Chia-Hao; Shih, Chuan-Chi; Cheng, Wei-Chung

    2017-01-01

    We previously presented the YM500 database, which contains >8000 small RNA sequencing (smRNA-seq) data sets and integrated analysis results for various cancer miRNome studies. In the updated YM500v3 database (http://ngs.ym.edu.tw/ym500/) presented herein, we not only focus on miRNAs but also on other functional small non-coding RNAs (sncRNAs), such as PIWI-interacting RNAs (piRNAs), tRNA-derived fragments (tRFs), small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs). There is growing knowledge of the role of sncRNAs in gene regulation and tumorigenesis. We have also incorporated >10 000 cancer-related RNA-seq and >3000 more smRNA-seq data sets into the YM500v3 database. Furthermore, there are two main new sections, ‘Survival' and ‘Cancer', in this updated version. The ‘Survival’ section provides the survival analysis results in all cancer types or in a user-defined group of samples for a specific sncRNA. The ‘Cancer’ section provides the results of differential expression analyses, miRNA–gene interactions and cancer miRNA-related pathways. In the ‘Expression’ section, sncRNA expression profiles across cancer and sample types are newly provided. Cancer-related sncRNAs hold potential for both biotech applications and basic research. PMID:27899625

  6. The Government Finance Database: A Common Resource for Quantitative Research in Public Financial Analysis.

    Science.gov (United States)

    Pierson, Kawika; Hand, Michael L; Thompson, Fred

    2015-01-01

    Quantitative public financial management research focused on local governments is limited by the absence of a common database for empirical analysis. While the U.S. Census Bureau distributes government finance data that some scholars have utilized, the arduous process of collecting, interpreting, and organizing the data has led its adoption to be prohibitive and inconsistent. In this article we offer a single, coherent resource that contains all of the government financial data from 1967-2012, uses easy to understand natural-language variable names, and will be extended when new data is available.

  7. Research Update: The materials genome initiative: Data sharing and the impact of collaborative ab initio databases

    Science.gov (United States)

    Jain, Anubhav; Persson, Kristin A.; Ceder, Gerbrand

    2016-05-01

    Materials innovations enable new technological capabilities and drive major societal advancements but have historically required long and costly development cycles. The Materials Genome Initiative (MGI) aims to greatly reduce this time and cost. In this paper, we focus on data reuse in the MGI and, in particular, discuss the impact of three different computational databases based on density functional theory methods to the research community. We also discuss and provide recommendations on technical aspects of data reuse, outline remaining fundamental challenges, and present an outlook on the future of MGI's vision of data sharing.

  8. Scientific Research Database of the 2008 Ms8.0 Wenchuan Earthquake

    Science.gov (United States)

    Liang, C.; Yang, Y.; Yu, Y.

    2013-12-01

    Nearly 5 years after the 2008 Ms8.0 Wenchuan Earthquake, the Ms7.0 Lushan earthquake stroke 70km away along the same fault system. Given the tremendous life loss and property damages as well as the short time and distance intervals between the two large magnitude events, the scientific probing into their causing factors and future seismic activities in the nearby region will continue to be in the center of earthquake research in China and even the world for years to come. In the past five years, scientists have made significant efforts to study the Wenchuan earthquake from various aspects using different datasets and methods. Their studies cover a variety of topics including seismogenic environment, earthquake precursors, rupture process, co-seismic phenomenon, hazard relief, reservoir induced seismicity and more. These studies have been published in numerous journals in Chinese, English and many other languages. In addition, 54 books regarding to this earthquake have been published. The extremely diversified nature of all publications makes it very difficult and time-consuming, if not impossible, to sort out information needed by individual researcher in an efficient way. An information platform that collects relevant scientific information and makes them accessible in various ways can be very handy. With this mission in mind, the Earthquake Research Group in the Chengdu University of Technology has developed a website www.wceq.org to attack this target: (1) articles published by major journals and books are recorded into a database. Researchers will be able to find articles by topics, journals, publication dates, authors and keywords e.t.c by a few clicks; (2) to fast track the latest developments, researchers can also follow upon updates in the current month, last 90days, 180 days and 365 days by clicking on corresponding links; (3) the modern communication tools such as Facebook, Twitter and their Chinese counterparts are accommodated in this site to share

  9. Monitoring of equine health in Denmark: the importance, purpose, research areas and content of a future database.

    Science.gov (United States)

    Hartig, Wendy; Houe, Hans; Andersen, Pia Haubro

    2013-04-01

    The plentiful data on Danish horses are currently neither organized nor easily accessible, impeding register-based epidemiological studies on Danish horses. A common database could be beneficial. In principle, databases can contain a wealth of information, but no single database can serve every purpose. Hence the establishment of a Danish equine health database should be preceded by careful consideration of its purpose and content, and stakeholder attitudes should be investigated. The objectives of the present study were to identify stakeholder attitudes to the importance, purpose, research areas and content of a health database for horses in Denmark. A cross-sectional study was conducted with 13 horse-related stakeholder groups in Denmark. The groups surveyed included equine veterinarians, researchers, veterinary students, representatives from animal welfare organizations, horse owners, trainers, farriers, authority representatives, ordinary citizens, and representatives from laboratories, insurance companies, medical equipment companies and pharmaceutical companies. Supplementary attitudes were inferred from qualitative responses. The overall response rate for all stakeholder groups was 45%. Stakeholder group-specific response rates were 27-80%. Sixty-eight percent of questionnaire respondents thought a national equine health database was important. Most respondents wanted the database to contribute to improved horse health and welfare, to be used for research into durability and disease heritability, and to serve as a basis for health declarations for individual horses. The generally preferred purpose of the database was thus that it should focus on horse health and welfare rather than on performance or food safety, and that it should be able to function both at a population and an individual horse level. In conclusion, there is a positive attitude to the establishment of a health database for Danish horses. These results could enrich further reflection on the

  10. National Database for Autism Research (NDAR): Big Data Opportunities for Health Services Research and Health Technology Assessment.

    Science.gov (United States)

    Payakachat, Nalin; Tilford, J Mick; Ungar, Wendy J

    2016-02-01

    The National Database for Autism Research (NDAR) is a US National Institutes of Health (NIH)-funded research data repository created by integrating heterogeneous datasets through data sharing agreements between autism researchers and the NIH. To date, NDAR is considered the largest neuroscience and genomic data repository for autism research. In addition to biomedical data, NDAR contains a large collection of clinical and behavioral assessments and health outcomes from novel interventions. Importantly, NDAR has a global unique patient identifier that can be linked to aggregated individual-level data for hypothesis generation and testing, and for replicating research findings. As such, NDAR promotes collaboration and maximizes public investment in the original data collection. As screening and diagnostic technologies as well as interventions for children with autism are expensive, health services research (HSR) and health technology assessment (HTA) are needed to generate more evidence to facilitate implementation when warranted. This article describes NDAR and explains its value to health services researchers and decision scientists interested in autism and other mental health conditions. We provide a description of the scope and structure of NDAR and illustrate how data are likely to grow over time and become available for HSR and HTA.

  11. The role of patent and non-patent databases in patent research in universities

    Science.gov (United States)

    Tolstaya, A. M.; Suslina, I. V.; Tolstaya, P. M.

    2017-01-01

    This studies deal with the description and systematization of the popular patent retrieval resources. The importance of the non-patent information when conducting patent research for the intellectual property created in educational and scientific activity of the university is highlighted. The differences in the patent and non-patent information are found out. Based on the databases` analysis the authors conducted the patent research on "Wireless endoscopic capsules" (development of the NRNU MEPhI). This study can be used to facilitate the university work on the new product development in order to improve the efficiency of the process of the commercialization of the intellectual activity results, including the entering the international market.

  12. Development of a Local Entomological Database for Education and Research using Simulation (Virtual Methods

    Directory of Open Access Journals (Sweden)

    Emad I. Khater

    2014-01-01

    Full Text Available Bioinformatics has been regarded as one of the rapidly-evolving fields with enormous impact on the history of life and biomedical sciences. It is an interdisciplinary science that integrates life sciences, mathematics and computer science in order to extract meaningful biological insights from large data sets of raw DNA and protein sequences. Our objective was the development of an entomogenomics database (provisionally named EntomDB for education and research in entomology (entomology is the science of insects. This DB includes DNA/protein sequence data selected from genomes of major insect models of importance in biology and biomedical research. EntomDB will represent a customized easy, interactive and self-learning resource tool for beginner users in poor-resource settings. This will enable the users to learn basic skills in bioinformatics and genomics, needlessly to search through the numerous databases currently available on the World-Wide Web with their complex interfaces and contents. EntomDB will help students and young researchers in studying the primary structure, splicing, and translation and predict function of different genes by using simple simulation methods. It is also designed to be adaptable to work off-line, in case no internet connection is available. EntomDB is primarily designed for entomology discipline; however, it can easily be adapted for other disciplines in life and biomedical sciences. EntomDB will have important educational and developmental outcomes in promoting bioinformatics learning in the developing world and provide affordable first-level training for advanced degree and research levels.

  13. 版权法上的公共领域研究%On public domain in copyright law

    Institute of Scientific and Technical Information of China (English)

    黄汇

    2009-01-01

    Public domain is a core rule of copyright law, under which various creative materials are available for an author to use without charge or liability for infringement, hence ensuring the effective implementation of copyright law.Public domain is characterized by openness, public ownership, irrevocability and formality. Based on the premise that the author's work will not be interfered, public domain ultimately aims at the enlargement of its own universe and prosperity of the culture of human society. Its introduction into copyright law satisfies both historical and logical demands. Without its acknowledgement,copyright cannot be justified. In that sense, public domain and copyright can be deemed as twins. Public domain is not only an existing institution, but also an ideological tendency or a methodology. It has evaluative and inspective values towards copyright. It is an important precondition of copy-rights, and what is more, an important measure for controlling the expansion and realizing the purpose of copyright.%公共领域是版权法的核心,它是保证作者有效运用各种创作素材从而使版权的其余部分得以良好运转的工具.公共领域具有开放性、有主性、不可撤销性和程序性等特征,它以保证作者的创作为前提,却最终以自身的不断扩大和人类社会的文化繁衍为依归.公共领域在版权法上的生成既是历史的,更是逻辑的.没有公共领域的被承认,也就没有版权的正当性可言,因此公共领域和版权实际上一同诞生.公共领域不仅是一种制度存在物,它更是一种思想倾向和方法论,公共领域对版权具有评价和检视功能,它既是版权运行的重要前提,又是控制版权扩张和实现版权目的的重要手段.

  14. NASA's Astromaterials Database: Enabling Research Through Increased Access to Sample Data, Metadata and Imagery

    Science.gov (United States)

    Evans, Cindy; Todd, Nancy

    2014-01-01

    The Astromaterials Acquisition & Curation Office at NASA's Johnson Space Center (JSC) is the designated facility for curating all of NASA's extraterrestrial samples. Today, the suite of collections includes the lunar samples from the Apollo missions, cosmic dust particles falling into the Earth's atmosphere, meteorites collected in Antarctica, comet and interstellar dust particles from the Stardust mission, asteroid particles from Japan's Hayabusa mission, solar wind atoms collected during the Genesis mission, and space-exposed hardware from several missions. To support planetary science research on these samples, JSC's Astromaterials Curation Office hosts NASA's Astromaterials Curation digital repository and data access portal [http://curator.jsc.nasa.gov/], providing descriptions of the missions and collections, and critical information about each individual sample. Our office is designing and implementing several informatics initiatives to better serve the planetary research community. First, we are re-hosting the basic database framework by consolidating legacy databases for individual collections and providing a uniform access point for information (descriptions, imagery, classification) on all of our samples. Second, we continue to upgrade and host digital compendia that summarize and highlight published findings on the samples (e.g., lunar samples, meteorites from Mars). We host high resolution imagery of samples as it becomes available, including newly scanned images of historical prints from the Apollo missions. Finally we are creating plans to collect and provide new data, including 3D imagery, point cloud data, micro CT data, and external links to other data sets on selected samples. Together, these individual efforts will provide unprecedented digital access to NASA's Astromaterials, enabling preservation of the samples through more specific and targeted requests, and supporting new planetary science research and collaborations on the samples.

  15. TarNet: An Evidence-Based Database for Natural Medicine Research.

    Science.gov (United States)

    Hu, Ruifeng; Ren, Guomin; Sun, Guibo; Sun, Xiaobo

    2016-01-01

    Complex diseases seriously threaten human health. Drug discovery approaches based on "single genes, single drugs, and single targets" are limited in targeting complex diseases. The development of new multicomponent drugs for complex diseases is imperative, and the establishment of a suitable solution for drug group-target protein network analysis is a key scientific problem that must be addressed. Herbal medicines have formed the basis of sophisticated systems of traditional medicine and have given rise to some key drugs that remain in use today. The search for new molecules is currently taking a different route, whereby scientific principles of ethnobotany and ethnopharmacognosy are being used by chemists in the discovery of different sources and classes of compounds. In this study, we developed TarNet, a manually curated database and platform of traditional medicinal plants with natural compounds that includes potential bio-target information. We gathered information on proteins that are related to or affected by medicinal plant ingredients and data on protein-protein interactions (PPIs). TarNet includes in-depth information on both plant-compound-protein relationships and PPIs. Additionally, TarNet can provide researchers with network construction analyses of biological pathways and protein-protein interactions (PPIs) associated with specific diseases. Researchers can upload a gene or protein list mapped to our PPI database that has been manually curated to generate relevant networks. Multiple functions are accessible for network topological calculations, subnetwork analyses, pathway analyses, and compound-protein relationships. TarNet will serve as a useful analytical tool that will provide information on medicinal plant compound-affected proteins (potential targets) and system-level analyses for systems biology and network pharmacology researchers. TarNet is freely available at http://www.herbbol.org:8001/tarnet, and detailed tutorials on the program are also

  16. TarNet: An Evidence-Based Database for Natural Medicine Research.

    Directory of Open Access Journals (Sweden)

    Ruifeng Hu

    Full Text Available Complex diseases seriously threaten human health. Drug discovery approaches based on "single genes, single drugs, and single targets" are limited in targeting complex diseases. The development of new multicomponent drugs for complex diseases is imperative, and the establishment of a suitable solution for drug group-target protein network analysis is a key scientific problem that must be addressed. Herbal medicines have formed the basis of sophisticated systems of traditional medicine and have given rise to some key drugs that remain in use today. The search for new molecules is currently taking a different route, whereby scientific principles of ethnobotany and ethnopharmacognosy are being used by chemists in the discovery of different sources and classes of compounds.In this study, we developed TarNet, a manually curated database and platform of traditional medicinal plants with natural compounds that includes potential bio-target information. We gathered information on proteins that are related to or affected by medicinal plant ingredients and data on protein-protein interactions (PPIs. TarNet includes in-depth information on both plant-compound-protein relationships and PPIs. Additionally, TarNet can provide researchers with network construction analyses of biological pathways and protein-protein interactions (PPIs associated with specific diseases. Researchers can upload a gene or protein list mapped to our PPI database that has been manually curated to generate relevant networks. Multiple functions are accessible for network topological calculations, subnetwork analyses, pathway analyses, and compound-protein relationships.TarNet will serve as a useful analytical tool that will provide information on medicinal plant compound-affected proteins (potential targets and system-level analyses for systems biology and network pharmacology researchers. TarNet is freely available at http://www.herbbol.org:8001/tarnet, and detailed tutorials on the

  17. Turning text into research networks: information retrieval and computational ontologies in the creation of scientific databases.

    Directory of Open Access Journals (Sweden)

    Flávio Ceci

    Full Text Available BACKGROUND: Web-based, free-text documents on science and technology have been increasing growing on the web. However, most of these documents are not immediately processable by computers slowing down the acquisition of useful information. Computational ontologies might represent a possible solution by enabling semantically machine readable data sets. But, the process of ontology creation, instantiation and maintenance is still based on manual methodologies and thus time and cost intensive. METHOD: We focused on a large corpus containing information on researchers, research fields, and institutions. We based our strategy on traditional entity recognition, social computing and correlation. We devised a semi automatic approach for the recognition, correlation and extraction of named entities and relations from textual documents which are then used to create, instantiate, and maintain an ontology. RESULTS: We present a prototype demonstrating the applicability of the proposed strategy, along with a case study describing how direct and indirect relations can be extracted from academic and professional activities registered in a database of curriculum vitae in free-text format. We present evidence that this system can identify entities to assist in the process of knowledge extraction and representation to support ontology maintenance. We also demonstrate the extraction of relationships among ontology classes and their instances. CONCLUSION: We have demonstrated that our system can be used for the conversion of research information in free text format into database with a semantic structure. Future studies should test this system using the growing number of free-text information available at the institutional and national levels.

  18. A Green's function database platform for seismological research and education: applications and examples

    Science.gov (United States)

    Heimann, Sebastian; Kriegerowski, Marius; Dahm, Torsten; Simone, Cesca; Wang, Rongjiang

    2016-04-01

    The study of seismic sources from measured waveforms requires synthetic elementary seismograms (Green's functions, GF) calculated for specific earth models and source receiver geometries. Since the calculation of GFs is computationally expensive and requires careful parameter testing and quality control, pre-calculated GF databases, which can be re-used for different types of applications, can be of advantage. We developed a GF database web platform for the seismological community (http://kinherd.org/), where a researcher can share Green's function stores and retrieve synthetic seismograms on the fly for various point and extended earthquake source models for many different earth models at local, regional and global scale. This web service is part of a rich new toolset for the creation and handling of Green's functions and synthetic seismograms (http://emolch.github.com/pyrocko/gf). It can be used off-line or in client mode. We demonstrate core features of the GF platform with different applications on global, regional and local scales. These include the automatic inversion of kinematic source parameter from teleseismic body waves, the improved depth estimate of shallow induced earthquakes from regional seismological arrays, or the relative moment tensor inversion of local earthquakes from volcanic induced seismicity.

  19. Research progress in muscle-derived stem cells Literature retrieval results based on international database

    Institute of Scientific and Technical Information of China (English)

    Li Zhang; Wei Wang

    2012-01-01

    OBJECTIVE: To identify global research trends of muscle-derived stem cells (MDSCs) using a bibliometric analysis of the Web of Science, Research Portfolio Online Reporting Tools of the National Institutes of Health (NIH), and the Clinical Trials registry database (ClinicalTrials.gov). DATA RETRIEVAL: We performed a bibliometric analysis of data retrievals for MDSCs from 2002 to 2011 using the Web of Science, NIH, and ClinicalTrials.gov. MAIN OUTCOME MEASURES: (1) Type of literature; (2) annual publication output; (3) distribution according to journals; (4) distribution according to country; (5) distribution according to institution; (6) top cited authors over the last 10 years; (7) projects financially supported by the NIH; and (8) clinical trials registered.RESULTS: (1) In all, 802 studies on MDSCs appeared in the Web of Science from 2002 to 2011, almost half of which derived from American authors and institutes. The number of studies on MDSCs has gradually increased over the past 10 years. Most papers on MDSCs appeared in journals with a particular focus on cell biology research, such as Experimental Cell Research, Journal of Cell Science, and PLoS One. (2) Eight MDSC research projects have received over US$6 billion in funding from the NIH. The current project led by Dr. Johnny Huard of the University of Pittsburgh-"Muscle-Based Tissue Engineering to Improve Bone Healing"-is supported by the NIH. Dr. Huard has been the most productive and top-cited author in the field of gene therapy and adult stem cell research in the Web of Science over last 10 years. (3) On ClinicalTrials.gov, "Muscle Derived Cell Therapy for Bladder Exstrophy Epispadias Induced Incontinence" Phase 1 is registered and sponsored by Johns Hopkins University and has been led by Dr. John P. Gearhart since November 2009.CONCLUSION: From our analysis of the literature and research trends, we found that MDSCs may offer further benefits in regenerative medicine.

  20. Proyecto AVIS: a Spanish open access bird database available for research

    Directory of Open Access Journals (Sweden)

    Sara Varela

    2014-12-01

    Full Text Available Proyecto AVIS1 is an open access citizen science database that stores information collected by amateur ornithologists about bird occurrences and abundance in Spain. Proyecto AVIS was launched in 2005 and today stores data from 415 species (ca. 90% of bird species in Spain; it covers 30% of the Spanish territory, including the Canary Islands in the Atlantic Ocean and the Balearic Islands in the Mediterranean Sea. Here, we acknowledge the work of all the volunteers that have gathered bird records in the field and uploaded these observations over the last 10 years, and introduce Proyecto AVIS to a broader community of biogeographers and macroecologists to promote its use for research

  1. PlantDB – a versatile database for managing plant research

    Directory of Open Access Journals (Sweden)

    Gruissem Wilhelm

    2008-01-01

    Full Text Available Abstract Background Research in plant science laboratories often involves usage of many different species, cultivars, ecotypes, mutants, alleles or transgenic lines. This creates a great challenge to keep track of the identity of experimental plants and stored samples or seeds. Results Here, we describe PlantDB – a Microsoft® Office Access database – with a user-friendly front-end for managing information relevant for experimental plants. PlantDB can hold information about plants of different species, cultivars or genetic composition. Introduction of a concise identifier system allows easy generation of pedigree trees. In addition, all information about any experimental plant – from growth conditions and dates over extracted samples such as RNA to files containing images of the plants – can be linked unequivocally. Conclusion We have been using PlantDB for several years in our laboratory and found that it greatly facilitates access to relevant information.

  2. Creating a data exchange strategy for radiotherapy research: towards federated databases and anonymised public datasets.

    Science.gov (United States)

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Büttner, Daniel; Debus, Jürgen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A; Lewensohn, Rolf; Lühr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Björn; Zips, Daniel; Baumann, Michael

    2014-12-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational models to support medical decisions (e.g. risk/benefit analysis of treatment options) represent just a fraction of the potential benefits of medical data-pooling. Distributed machine learning and knowledge exchange from federated databases can be considered as one beyond other attractive approaches for knowledge generation within "Big Data". Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning data, are deemed to be fundamental elements for large multi-centre studies in the field of radiation therapy and oncology. To fully utilise the captured medical information, the study data have to be more than just an electronic version of a traditional (un-modifiable) paper CRF. Challenges that have to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data exchange in the field of radiation therapy and oncology.

  3. Evolution of Industry Knowledge in the Public Domain: Prior Art Searching for Software Patents

    Directory of Open Access Journals (Sweden)

    Jinseok Park

    2005-03-01

    Full Text Available Searching prior art is a key part of the patent application and examination processes. A comprehensive prior art search gives the inventor ideas as to how he can improve or circumvent existing technology by providing up to date knowledge on the state of the art. It also enables the patent applicant to minimise the likelihood of an objection from the patent office. This article explores the characteristics of prior art associated with software patents, dealing with difficulties in searching prior art due to the lack of resources, and considers public contribution to the formation of prior art databases. It addresses the evolution of electronic prior art in line with technological development, and discusses laws and practices in the EPO, USPTO, and the JPO in relation to the validity of prior art resources on the Internet. This article also investigates the main features of searching sources and tools in the three patent offices as well as non-patent literature databases. Based on the analysis of various searching databases, it provides some strategies of efficient prior art searching that should be considered for software-related inventions.

  4. Cancer studies based on secondary data analysis of the Taiwan's National Health Insurance Research Database

    Science.gov (United States)

    Chiang, Jui-Kun; Lin, Chih-Wen; Wang, Chun-Lung; Koo, Malcolm; Kao, Yee-Hsin

    2017-01-01

    Abstract There has been a surge in the academic publication output based on secondary analyses of the data from the Taiwan's National Health Insurance claim records. It has become a challenge to comprehend such a rapid expansion of the literature. Therefore, this study aimed to explore the conceptual content of National Health Insurance Research Database-based cancer research, using the abstract of articles extracted from PubMed between 2002 and 2015. Search terms including “National Health Insurance Research Database (NHIRD) AND Taiwan,” “Taiwan AND population-based,” and “Taiwan AND nationwide” were used to search in PubMed with the publication date limited to between 1997 and 2015. The retrieved articles were manually screened to retain only those that were cancer-related and were based on secondary data analysis of the NHIRD. A total 589 articles were selected for subsequent text mining using the R software. Among the 589 articles, the top 5 most studied cancer types were breast (16.3%), lung (11.4%), colorectal (10.4%), liver (8.3%), and prostate (7.5%). The articles that received the highest number of citations by PubMed Central articles were cited 92 times. The top 3 most frequently occurred keywords in the abstracts of the 589 articles were cancer, patient, and risk, with 3670, 2535, and 1652 times, respectively. Analysis of key conception indicated that the most common conceptions were diabetes, survival, breast cancer, lung cancer, and colorectal cancer. In conclusion, in this study of 589 published articles on secondary data analysis of the NHIRD, indexed by PubMed between 2002 and 2015, we found that while the risk factors of cancer, treatment of cancer, and survival of cancer patients were popular research topics, end-of-life cancer care issues were less studied. Further studies should explore these areas since they are as important as treatment of the disease itself for many patients. PMID:28445277

  5. Production of radioactive phantoms using a standard inkjet printer and the public domain multi-printing code GENIA.

    Science.gov (United States)

    Scafè, R; Auer, P; Bennati, P; La Porta, L; Pisacane, F; Cinti, M N; Pellegrini, R; De Vincentis, G; Conte, G; Pani, R

    2011-10-01

    The public domain code GENIA, based on multi-printing method for producing surface sources with appropriate radioactivity, is described. The conventional technique, running on standard inkjet printer with radio-marked ink filling, is improved by repeating elementary printing commands in the same band. Well outlined sources with adjustable radioactivity can be obtained without refilling. The intrinsic limitation of printable radioactivity, depending on the value available at nozzles at printing time, was overcome. In addition the method permits the accurate calibration of the amount of activity released onto the paper.

  6. A synopsis of original research projects published in scientific database in the Russian Federation.

    Science.gov (United States)

    Smirnova, Daria; Pavlichenko, Alexey; Karpenko, Olga; Schmeleva, Liubov; Morozov, Petr

    2015-06-01

    The article describes the current state of scientific publications in the field of psychiatry in the Russian Federation. Issues of academic dissertations, lack of access to recent Russian language research in foreign databases, and recent reforms in the Ministry of Education and Science for overcoming these limitations are discussed in detail. Four exemplary dissertation studies published in Russian language are summarized. The first research examines the contribution of patient's verbal behavior to the reliable diagnosis of mild depression, identifying objective signs for distinguishing it from normal sadness; the mood component influenced the whole mental status and was represented in both structure and semantics of patients' speech. The second paper describes the course of panic disorder with agoraphobia, with the notable results that debut of panic disorder with full-blown panic attacks, often declines to a second accompanied with agoraphobia, which after several years gives way to limited symptom attacks and decreased agoraphobic avoidance. The third study describes the high prevalence of affective and anxiety disorders in patients with diabetes mellitus type 1 and 2, and the role of personality traits in adherence to treatment in patients with poor glucose control. The fourth project uses functional MRI for probing the features of neuronal resting-state networks in patients with temporal lobe epilepsy; the association with affective symptoms provides a model for investigating the pathophysiology of mood disorder.

  7. The Developmental Brain Disorders Database (DBDB): a curated neurogenetics knowledge base with clinical and research applications.

    Science.gov (United States)

    Mirzaa, Ghayda M; Millen, Kathleen J; Barkovich, A James; Dobyns, William B; Paciorkowski, Alex R

    2014-06-01

    The number of single genes associated with neurodevelopmental disorders has increased dramatically over the past decade. The identification of causative genes for these disorders is important to clinical outcome as it allows for accurate assessment of prognosis, genetic counseling, delineation of natural history, inclusion in clinical trials, and in some cases determines therapy. Clinicians face the challenge of correctly identifying neurodevelopmental phenotypes, recognizing syndromes, and prioritizing the best candidate genes for testing. However, there is no central repository of definitions for many phenotypes, leading to errors of diagnosis. Additionally, there is no system of levels of evidence linking genes to phenotypes, making it difficult for clinicians to know which genes are most strongly associated with a given condition. We have developed the Developmental Brain Disorders Database (DBDB: https://www.dbdb.urmc.rochester.edu/home), a publicly available, online-curated repository of genes, phenotypes, and syndromes associated with neurodevelopmental disorders. DBDB contains the first referenced ontology of developmental brain phenotypes, and uses a novel system of levels of evidence for gene-phenotype associations. It is intended to assist clinicians in arriving at the correct diagnosis, select the most appropriate genetic test for that phenotype, and improve the care of patients with developmental brain disorders. For researchers interested in the discovery of novel genes for developmental brain disorders, DBDB provides a well-curated source of important genes against which research sequencing results can be compared. Finally, DBDB allows novel observations about the landscape of the neurogenetics knowledge base.

  8. Food-pics: an image database for experimental research on eating and appetite

    Directory of Open Access Journals (Sweden)

    Jens eBlechert

    2014-06-01

    Full Text Available Our current environment is characterized by the omnipresence of food cues. The sight and smell of real foods, but also graphically depictions of appetizing foods, can guide our eating behavior, for example, by eliciting food craving and influencing food choice. The relevance of visual food cues on human information processing has been demonstrated by a growing body of studies employing food images across the disciplines of psychology, medicine, and neuroscience. However, currently used food image sets vary considerably across laboratories and image characteristics (contrast, brightness, etc. and food composition (calories, macronutrients, etc. are often unspecified. These factors might have contributed to some of the inconsistencies of this research. To remedy this, we developed food-pics, a picture database comprising 568 food images and 315 non-food images along with detailed meta-data. A total of N = 1988 individuals with large variance in age and weight from German speaking countries and North America provided normative ratings of valence, arousal, palatability, desire to eat, recognizability and visual complexity. Furthermore, data on macronutrients (g, energy density (kcal, and physical image characteristics (color composition, contrast, brightness, size, complexity are provided. The food-pics image data base is freely available under the creative commons license with the hope that the set will facilitate standardization and comparability across studies and advance experimental research on the determinants of eating behavior.

  9. Governance and oversight of researcher access to electronic health data: the role of the Independent Scientific Advisory Committee for MHRA database research, 2006-2015.

    Science.gov (United States)

    Waller, P; Cassell, J A; Saunders, M H; Stevens, R

    2017-03-01

    In order to promote understanding of UK governance and assurance relating to electronic health records research, we present and discuss the role of the Independent Scientific Advisory Committee (ISAC) for MHRA database research in evaluating protocols proposing the use of the Clinical Practice Research Datalink. We describe the development of the Committee's activities between 2006 and 2015, alongside growth in data linkage and wider national electronic health records programmes, including the application and assessment processes, and our approach to undertaking this work. Our model can provide independence, challenge and support to data providers such as the Clinical Practice Research Datalink database which has been used for well over 1,000 medical research projects. ISAC's role in scientific oversight ensures feasible and scientifically acceptable plans are in place, while having both lay and professional membership addresses governance issues in order to protect the integrity of the database and ensure that public confidence is maintained.

  10. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers,Asian Agricultural Research eventually passes the extremely strict appraisal,to be indexed by CABI’ s full text repository.CABI is globally acclaimed as one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry.Since inception of publication,Asian Agricultural Research has also been indexed by AGE Database,Naresuan University Library,Rural Development Foundation of India,Royal Tropical Institute and CSA Illumina.Editorial office of Asian Agricultural Research CABI Database CABI Database,one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry,is compiled by Centre for Agricultural Bioscience International.This data base,since 1973,has indexed 5

  11. RDD Databases

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This database was established to oversee documents issued in support of fishery research activities including experimental fishing permits (EFP), letters of...

  12. Research on Performance Evaluation of Biological Database based on Layered Queuing Network Model under the Cloud Computing Environment

    Directory of Open Access Journals (Sweden)

    Zhengbin Luo

    2013-06-01

    Full Text Available To evaluate the performance of biological database based on layered queuing network model and under cloud computing environment is a premise, as well as an important step for biological database optimization. Based on predecessors’ researches concerning computer software and hardware performance evaluation under cloud environment, the study has further constructed a model system to evaluate the performance of biological database based on layered queuing network model and under cloud environment. Moreover, traditional layered queuing network model is also optimized and upgraded in this process. After having constructed the performance evaluation system, the study applies laboratory experiment method to test the validity of the constructed performance model. Shown by the test result, this model is effective in evaluating the performance of biological system under cloud environment and the predicted result is quite close to the tested result. This has demonstrated the validity of the model in evaluating the performance of biological database.

  13. The research of network database security technology based on web service

    Science.gov (United States)

    Meng, Fanxing; Wen, Xiumei; Gao, Liting; Pang, Hui; Wang, Qinglin

    2013-03-01

    Database technology is one of the most widely applied computer technologies, its security is becoming more and more important. This paper introduced the database security, network database security level, studies the security technology of the network database, analyzes emphatically sub-key encryption algorithm, applies this algorithm into the campus-one-card system successfully. The realization process of the encryption algorithm is discussed, this method is widely used as reference in many fields, particularly in management information system security and e-commerce.

  14. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    DEFF Research Database (Denmark)

    Jones, Roy; Wilkinson, David; Lopez, Oscar L

    2011-01-01

    Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical...... community because of concerns that commercial, rather than scientific, goals are the primary purpose of such endeavours. Thus, there are few examples of sustained collaboration between leading academic clinical researchers and industry professionals in a large-scale data mining project. We present here...

  15. LLNL Middle East and North Africa and Former Soviet Union Research Database

    Energy Technology Data Exchange (ETDEWEB)

    O' Boyle, J.L.; Ruppert, S.D.; Hauk, T.F.; Dodge, D.; Firpo, M.

    2000-07-14

    The Lawrence Livermore National Laboratory (LLNL) Ground-Based Nuclear Explosion Monitoring (GNEM) R and D program has made significant progress populating a comprehensive Seismic Research knowledge Base (SRKB) and deriving calibration parameters for the Middle East and North Africa (ME/NA) and Former Soviet Union (FSU) regions. The LLNL SRKB provides not only a coherent framework in which to store and organize very large volumes of collected seismic waveforms, associated event parameter information, and spatial contextual data, but also provides an efficient data processing/research environment for deriving location and discrimination correction surfaces. The SRKB is a flexible and extensible framework consisting of a relational database (RDB), Geographical Information System (GIS), and associated product/data visualization and data management tools. This SRKB framework is designed to accommodate large volumes of data (over 2 million waveforms from 20,000 events) in diverse formats from many sources in addition to maintaining detailed quality control and metadata. Using the SRKB framework, they are combining travel-time observations, event characterization studies, and regional tectonic models to assemble a library of ground truth information and phenomenology correction surfaces required for support of the ME/NA and FSU regionalization program. Corrections and parameters distilled from the LLNL SRKB provide needed contributions to the DOE Knowledge Base (DOE KB) for the ME/NA and FSU regions and will help improve monitoring for underground nuclear testing. The LLNL research products will facilitate calibration of IMS stations (primary and auxiliary), their surrogates (if not yet installed) and selected gamma stations necessary to complete the above tasks in the ME/NA and FSU regions. They present expanded lookup tables for critical station parameter information (including location and response) and a new integrated and reconciled event catalog dataset including

  16. FishPathogens.eu a new database in the research of aquatic animal diseases

    DEFF Research Database (Denmark)

    Jonstrup, Søren Peter; Gray, T.; Olesen, Niels Jørgen

    We live in a world where the amount of information available is enormous. In order to keep track of the available knowledge, databases are needed to collect, store, and sort it. Www.fishpathogens.eu is a database developed and maintained by the European Union Reference Laboratory for Fish Diseases...

  17. Advances in Parallel Computing and Databases for Digital Pathology in Cancer Research

    Science.gov (United States)

    2016-11-13

    be used in conjunction for wider analysis. • In-database analytics Using basic linear algebra ap- proaches, several common processing steps such as...and in-database linear algebra operations that are well suited for the storage and analysis of biomedical imaging data. SciDB is a full ACID (atomicity

  18. Patterns of Undergraduates' Use of Scholarly Databases in a Large Research University

    Science.gov (United States)

    Mbabu, Loyd Gitari; Bertram, Albert; Varnum, Ken

    2013-01-01

    Authentication data was utilized to explore undergraduate usage of subscription electronic databases. These usage patterns were linked to the information literacy curriculum of the library. The data showed that out of the 26,208 enrolled undergraduate students, 42% of them accessed a scholarly database at least once in the course of the entire…

  19. Evidence for ASD recurrence rates and reproductive stoppage from large UK ASD research family databases.

    Science.gov (United States)

    Wood, Claire L; Warnell, Frances; Johnson, Mary; Hames, Annette; Pearce, Mark S; McConachie, Helen; Parr, Jeremy R

    2015-02-01

    Following a diagnosis of a developmental disorder such as autism spectrum disorder (ASD) in early childhood, parents may decide to have fewer children than previously planned. The tendency for families to halt reproduction after receiving a diagnosis for one child is known as reproductive stoppage. Stoppage may lead to an underestimate of recurrence risk estimates of parents having more than one child with ASD. Using two large UK ASD family databases, we investigated recurrence rates for ASD and evidence for reproductive stoppage for both ASD and undiagnosed ASD/broader autism phenotype in a subgroup of families. Reproductive stoppage was tested for using the Mann-Whitney U-test to disprove the null hypothesis that affected and nonaffected children were distributed randomly by birth order. Dahlberg's later-sib method was used to estimate recurrence risk and take stoppage into account. Data were available from 299 families (660 children) including 327 with ASD. Ten percent of the complete families had more than one child with an ASD. Using Dahlberg's later-sib method, the recurrence risk for ASD was 24.7% overall and 50.0% in families with two or more older siblings with ASD. Children with ASD were born significantly later in families than those without ASD in all sibship combinations. This study shows strong evidence that ASD is associated with reproductive stoppage. These data have important implications for family planning and genetic counseling. © 2014 International Society for Autism Research, Wiley Periodicals, Inc.

  20. The PubChemQC project: A large chemical database from the first principle calculations

    Science.gov (United States)

    Maho, Nakata

    2015-12-01

    In this research, we have been constructing a large database of molecules by ab initio calculations. Currently, we have over 1.53 million entries of 6-31G* B3LYP optimized geometries and ten excited states by 6-31+G* TDDFT calculations. To calculate molecules, we only refer the InChI (International Chemical Identifier) representation of chemical formula by the International Union of Pure and Applied Chemistry (IUPAC), thus, no reference to experimental data. These results are open to public at http://pubchemqc.riken.jp/. The molecular data have been taken from the PubChem Project (http://pubchem.ncbi.nlm.nih.gov/) which is one of the largest in the world (approximately 63 million molecules are listed) and free (public domain) database. Our final goal is, using these data, to develop a molecular search engine or molecular expert system to find molecules which have desired properties.

  1. The PubChemQC Project: a large chemical database from the first principle calculations

    CERN Document Server

    Nakata, Maho

    2015-01-01

    In this research, we have been constructing a large database of molecules by {\\it ab initio} calculations. Currently, we have over 1.53 million entries of 6-31G* B3LYP optimized geometries and ten excited states by 6-31+G* TDDFT calculations. To calculate molecules, we only refer the InChI (International Chemical Identifier) representation of chemical formula by the International Union of Pure and Applied Chemistry (IUPAC), thus, no reference to experimental data. These results are open to public at http://pubchemqc.riken.jp/. The molecular data have been taken from the PubChem Project (http://pubchem.ncbi.nlm.nih.gov/) which is one of the largest in the world (approximately 63 million molecules are listed) and free (public domain) database. Our final goal is, using these data, to develop a molecular search engine or molecular expert system to find molecules which have desired properties.

  2. Researches on Cartographic Database-Based Interactive Three-Dimensional Topographic Map

    Institute of Scientific and Technical Information of China (English)

    Jiang Wenping; Xi Daping

    2003-01-01

    With the development of computer graphics, the three-dimensional (3D) visualization brings new technological revolution to the traditional cartography. Therefore, the topographic 3D-map emerges to adapt to this technological revolution, and the applications of topographic 3D-map are spread rapidly to other relevant fields due to its incomparable advantage. The researches on digital map and the construction of map database offer strong technical support and abundant data source for this new technology, so the research and development of topographic 3D-map will receive greater concern. The basic data of the topographic 3D-map are rooted mainly in digital map and its basic model is derived from digital elevation model (DEM) and 3D-models of other DEM-based geographic features. In view of the potential enormous data and the complexity of geographic features, the dynamic representation of geographic information becomes the focus of the research of topographic 3D-map and also the prerequisite condition of 3D query and analysis. In addition to the equipment of hardware that are restraining, to a certain extent, the 3D representation, the data organization structure of geographic information will be the core problem of research on 3D-map. Level of detail (LOD), space partitioning, dynamic object loading (DOL) and object culling are core technologies of the dynamic 3D representation. The objectselection, attribute-query and model-editing are important functions and interaction tools for users with 3D-maps provided by topographic 3D-map system, all of which are based on the data structure of the 3Dmodel. This paper discusses the basic theories, concepts and cardinal principles of topographic 3D-map,expounds the basic way to organize the scene hierarchy of topographic 3D-map based on the node mechanism and studies the dynamic representation technologies of topographic 3D-map based on LOD, space partitioning, DOL and object culling. Moreover, such interactive operation

  3. The impact of standardizing the definition of visits on the consistency of multi-database observational health research.

    Science.gov (United States)

    Voss, Erica A; Ma, Qianli; Ryan, Patrick B

    2015-03-08

    Use of administrative claims from multiple sources for research purposes is challenged by the lack of consistency in the structure of the underlying data and definition of data across claims data providers. This paper evaluates the impact of applying a standardized revenue code-based logic for defining inpatient encounters across two different claims databases. We selected members who had complete enrollment in 2012 from the Truven MarketScan Commercial Claims and Encounters (CCAE) and the Optum Clinformatics (Optum) databases. The overall prevalence of inpatient conditions in the raw data was compared to that in the common data model (CDM) with the standardized visit definition applied. In CCAE, 87.18% of claims from 2012 that were classified as part of inpatient visits in the raw data were also classified as part of inpatient visits after the data were standardized to CDM, and this overlap was consistent from 2006 to 2011. In contrast, Optum had 83.18% concordance in classification of 2012 claims from inpatient encounters before and after standardization, but the consistency varied over time. The re-classification of inpatient encounters substantially impacted the observed prevalence of medical conditions occurring in the inpatient setting and the consistency in prevalence estimates between the databases. On average, before standardization, each condition in Optum was 12% more prevalent than that same condition in CCAE; after standardization, the prevalence of conditions had a mean difference of only 1% between databases. Amongst 7,039 conditions reviewed, the difference in the prevalence of 67% of conditions in these two databases was reduced after standardization. In an effort to improve consistency in research results across database one should review sources of database heterogeneity, such as the way data holders process raw claims data. Our study showed that applying the Observational Medical Outcomes Partnership (OMOP) CDM with a standardized approach for

  4. The Method of Analysis Derived Coefficients of Database as a New Method of Historical Research (for Example, a Database of Ballistic Parameters of Naval Artillery

    Directory of Open Access Journals (Sweden)

    Nicholas W. Mitiukov

    2015-12-01

    Full Text Available In paper there is proposed a new method of historical research, based on analysis of derivatives coefficients of database (for example, the form factor in the database of ballistic data. This method has a much greater protection from subjectivism and direct falsification, compared with the analysis obtained directly from the source of the numerical series, as any intentional or unintentional distortion of the raw data provides a significant contrast ratio derived from the average sample values. Application of this method to the analysis of ballistic data base of naval artillery allowed to find the facts, forcing a new look at some of the events in the history data on the German naval artillery before World War I, probably overpriced for disinformation opponents of the Entente; during the First World War, Spain, apparently held secret talks with the firm Bofors ended purchase of Swedish shells; the first Russian naval rifled guns were created obvious based on the project Blackly, not Krupp as traditionally considered.

  5. Recent Progress on Selected Topics in Database Research--A Report by Nine Young Chinese Researchers Working in the United States

    Institute of Scientific and Technical Information of China (English)

    Zhiyuan Chen; Chen Li; Jian Pei; Yufei Tao; Haixun Wang; Wei Wang; Jiong Yang; Jun Yang; Donghui Zhang

    2003-01-01

    The study on database technologies, or more generally, the technologies of dataand information management, is an important and active research field. Recently, many excitingresults have been reported. In this fast growing field, Chinese researchers play more and more activeroles. Research papers from Chinese scholars, both in China and abroad, appear in prestigious academic forums.In this paper, we, nine young Chinese researchers working in the United States, presentconcise surveys and report our recent progress on the selected fields that we are working on.Although the paper covers only a small number of topics and the selection of the topics is far frombalanced, we hope that such an effort would attract more and more researchers, especially thosein China, to enter the frontiers of database research and promote collaborations. For the obviousreason, the authors are listed alphabetically, while the sections are arranged in the order of theauthor list.

  6. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most author-itative and prestigious abstract data bases concerning agriculture and forestry. Since inception of publication, Asian Agri-cultural Research has also been indexed by AGE Database, Naresuan University Library, Rural Development Foundation of India, Royal Tropical Institute and CSA Illumina.

  7. Asian Agricultural Research is indexed by CABI, CSA Illumina, AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry. Since inception of publication, Asian Agricultural Research has also been indexed by AGE Database, Naresuan University Library, Rural Development Foundation of India, Royal Tropical Institute and CSA lllumina.

  8. Development and Initial Validation of Brief Public Domain RIASEC Marker Scales

    Science.gov (United States)

    Armstrong, Patrick Ian; Allison, Wyndolyn; Rounds, James

    2008-01-01

    Although commercially developed interest measures based on Holland's RIASEC types are effectively used in a variety of applied settings, these measures have somewhat limited research utility due to their length and copyright restrictions placed by the test publishers. In the present study, two sets of 8-item RIASEC scales were developed using…

  9. Genome databases

    Energy Technology Data Exchange (ETDEWEB)

    Courteau, J.

    1991-10-11

    Since the Genome Project began several years ago, a plethora of databases have been developed or are in the works. They range from the massive Genome Data Base at Johns Hopkins University, the central repository of all gene mapping information, to small databases focusing on single chromosomes or organisms. Some are publicly available, others are essentially private electronic lab notebooks. Still others limit access to a consortium of researchers working on, say, a single human chromosome. An increasing number incorporate sophisticated search and analytical software, while others operate as little more than data lists. In consultation with numerous experts in the field, a list has been compiled of some key genome-related databases. The list was not limited to map and sequence databases but also included the tools investigators use to interpret and elucidate genetic data, such as protein sequence and protein structure databases. Because a major goal of the Genome Project is to map and sequence the genomes of several experimental animals, including E. coli, yeast, fruit fly, nematode, and mouse, the available databases for those organisms are listed as well. The author also includes several databases that are still under development - including some ambitious efforts that go beyond data compilation to create what are being called electronic research communities, enabling many users, rather than just one or a few curators, to add or edit the data and tag it as raw or confirmed.

  10. Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

    Directory of Open Access Journals (Sweden)

    Christina M Lill

    Full Text Available More than 800 published genetic association studies have implicated dozens of potential risk loci in Parkinson's disease (PD. To facilitate the interpretation of these findings, we have created a dedicated online resource, PDGene, that comprehensively collects and meta-analyzes all published studies in the field. A systematic literature screen of -27,000 articles yielded 828 eligible articles from which relevant data were extracted. In addition, individual-level data from three publicly available genome-wide association studies (GWAS were obtained and subjected to genotype imputation and analysis. Overall, we performed meta-analyses on more than seven million polymorphisms originating either from GWAS datasets and/or from smaller scale PD association studies. Meta-analyses on 147 SNPs were supplemented by unpublished GWAS data from up to 16,452 PD cases and 48,810 controls. Eleven loci showed genome-wide significant (P < 5 × 10(-8 association with disease risk: BST1, CCDC62/HIP1R, DGKQ/GAK, GBA, LRRK2, MAPT, MCCC1/LAMP3, PARK16, SNCA, STK39, and SYT11/RAB25. In addition, we identified novel evidence for genome-wide significant association with a polymorphism in ITGA8 (rs7077361, OR 0.88, P  =  1.3 × 10(-8. All meta-analysis results are freely available on a dedicated online database (www.pdgene.org, which is cross-linked with a customized track on the UCSC Genome Browser. Our study provides an exhaustive and up-to-date summary of the status of PD genetics research that can be readily scaled to include the results of future large-scale genetics projects, including next-generation sequencing studies.

  11. Development of a Cost-Effective Database Software for Psychiatric Research: A Study From Tertiary Care Teaching Hospital

    Directory of Open Access Journals (Sweden)

    Sabu Karakkamandapam

    2010-10-01

    Full Text Available Background: Technological progression made drastic changes in health care. Still there is a growing concern about proper utilization of health information within hospitals for various research activities. Huge volumes of such health information in majority of hospitals are redundant due to lack of appropriate and cost-effective technological tools for retrieving relevant health information for research purpose. Objective: To develop a cost-effective and user-friendly computerized medical record database for psychiatry using available technology with the department. Methodology: Study performed at a tertiary care teaching hospital in Udupi district of South India. Various datasets from psychiatry medical records were utilized for the design and creation of database. A computerized database called PsyCase was developed with the help of technology available within the department. A 4612 patient’s data were entered into the PsyCase and subjected to various analyses. Results: Applications of PsyCase in various epidemiological studies were explored through performing numerous analyses with actual data. PsyCase was found effective in supporting psychiatric research as well as routine clinical and administrative activities. Conclusion: This study emphasizes need of appropriate use of technology available within a healthcare system to facilitate medical research in psychiatry and role of health information professional in such initiatives. Healthcare organization must focus on collective utilization of resources within the system to improve the utilization of health information for medical research.

  12. RESEARCH ON HLR MOBILITY DATABASE FAILURE RECOVERY AND PERFORMANCE ANALYSIS FOR CDMA2000 SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Liu Caixia; Yu Dingjiu; Cheng Dongnian; Tang Hongbo; Wu Jiangxing

    2004-01-01

    In this paper, a novel Home Location Register(HLR) mobility database recovery scheme is proposed. With database backing-up and signal sending as its key processes, the presented scheme is designed for the purpose of both decreasing system costs and reducing number of lost calls. In our scheme, an algorithm is developed for an HLR to identify such VLRs that there are new MSs roaming into them since the latest HLR database backing up. The identification of those VLRs is used by the HLR to send Unreliable Roaming Data Directive messages to each of them to get the correct location information of those new MSs. Additionally, two kinds of relationships, one between the number of lost calls and the database backing-up period and the other between the backing-up cost and the period, are well analyzed. Both analytical and numerical results indicate that there will be an optimal HLR database backing-up period if certain system parameters are given and the total cost can be consequently minimized.

  13. [The use of bibliographic databases by Spanish-speaking Latin American biomedical researchers: a cross-sectional study].

    Science.gov (United States)

    Ospina, Edgar Guillermo; Reveiz Herault, Ludovic; Cardona, Andrés Felipe

    2005-04-01

    To describe how Spanish-speaking biomedical professionals in Latin America access and utilize bibliographic databases. Based on a MEDLINE search, 2 515 articles published between August 2002 and August 2003 were identified that dealt with and/or had authors from 16 countries: Argentina, Bolivia, Chile, Colombia, Costa Rica, Cuba, Ecuador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Uruguay, and Venezuela. The search was limited to references to basic science, clinical science, or social medicine. A survey was sent by e-mail to researchers who lived in 15 of the 16 countries (the exception being Nicaragua). The survey asked about the researcher's area of work (basic science, clinical science, or public health), the level of skill in using databases, the frequency and type of access to the databases most utilized, the impact from not having access to the full text of articles when preparing a manuscript, and how the respondent usually obtained the full-text version of articles. A total of 586 e-mail messages with the survey were sent out, and 185 responses were received (32%). The databases most utilized to obtain biomedical information were MEDLINE (34.1%), general search engines (Google, Yahoo!, and AltaVista) (15.9%), on-line journals (9.8%), BIREME-LILACS (6.0%), BioMedNet (5.4%), the databases of the Centers for Disease Control and Prevention of the United States of America (5.2%), and the Cochrane Library (4.9%). Of the respondents, 64% said they had average or advanced abilities in using MEDLINE. However, 71% of the respondents did not use or were not aware of the MEDLINE Medical Subject Headings (MeSH), a controlled vocabulary established by the National Library of Medicine of the United States of America for indexing articles. The frequency of accessing the databases was similar in all the countries studied, without significant differences in terms of the type of access (authorized access to commercial databases, unauthorized access to

  14. ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes

    Energy Technology Data Exchange (ETDEWEB)

    Novichkov, Pavel S.; Ratnere, Igor; Wolf, Yuri I.; Koonin, Eugene V.; Dubchak, Inna

    2009-07-23

    The database of Alignable Tight Genomic Clusters (ATGCs) consists of closely related genomes of archaea and bacteria, and is a resource for research into prokaryotic microevolution. Construction of a data set with appropriate characteristics is a major hurdle for this type of studies. With the current rate of genome sequencing, it is difficult to follow the progress of the field and to determine which of the available genome sets meet the requirements of a given research project, in particular, with respect to the minimum and maximum levels of similarity between the included genomes. Additionally, extraction of specific content, such as genomic alignments or families of orthologs, from a selected set of genomes is a complicated and time-consuming process. The database addresses these problems by providing an intuitive and efficient web interface to browse precomputed ATGCs, select appropriate ones and access ATGC-derived data such as multiple alignments of orthologous proteins, matrices of pairwise intergenomic distances based on genome-wide analysis of synonymous and nonsynonymous substitution rates and others. The ATGC database will be regularly updated following new releases of the NCBI RefSeq. The database is hosted by the Genomics Division at Lawrence Berkeley National laboratory and is publicly available at http://atgc.lbl.gov.

  15. THE BUILDING OF THE SPATIAL DATABASE OF THE SATCHINEZ ORNITHOLOGICAL RESERVE AS A PREMISE OF MODERN ECOLOGICAL RESEARCH

    Directory of Open Access Journals (Sweden)

    M. Török-Oance

    2005-01-01

    Full Text Available The creation of a database for the Ornithological Reserve “The Satchinez Marshes” was a necessity for a modern and complex ecological research. This database offers the possibility of a precise localization of the species of plants and animals identified in the field and it is a genuine base for the identification of the main types of habitats and ecosystems in the reserve. With the help of the Terrain Numerical Model, the analysis, at the level of pixels, of the abiotical factors involved in the repartition of ecosystems was made possible, as well as the three-dimensions visualizations of all the results. With the help of the aerophotograms taken in 1963 and 1973, we reconstructed the situation of the reserve at that time, by creating a database of the terrain usage at that time. The same thing was done in 2004, using more diverse sources: cadastral planes, images taken from the satellite, air photos taken in the same year and last, but not least, data collected in the field in 2003-2004. At the same time, this database can be considered a bench-mark (for the year 2004 for the identification of the modifications that occurred during 1963 and 2004, but for future research as well.

  16. The Aspergillus Genome Database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community.

    Science.gov (United States)

    Arnaud, Martha B; Chibucos, Marcus C; Costanzo, Maria C; Crabtree, Jonathan; Inglis, Diane O; Lotia, Adil; Orvis, Joshua; Shah, Prachi; Skrzypek, Marek S; Binkley, Gail; Miyasato, Stuart R; Wortman, Jennifer R; Sherlock, Gavin

    2010-01-01

    The Aspergillus Genome Database (AspGD) is an online genomics resource for researchers studying the genetics and molecular biology of the Aspergilli. AspGD combines high-quality manual curation of the experimental scientific literature examining the genetics and molecular biology of Aspergilli, cutting-edge comparative genomics approaches to iteratively refine and improve structural gene annotations across multiple Aspergillus species, and web-based research tools for accessing and exploring the data. All of these data are freely available at http://www.aspgd.org. We welcome feedback from users and the research community at aspergillus-curator@genome.stanford.edu.

  17. Workshop report: Identifying opportunities for global integration of toxicogenomics databases, 26-27 June 2013, Research Triangle Park, NC, USA.

    Science.gov (United States)

    Hendrickx, Diana M; Boyles, Rebecca R; Kleinjans, Jos C S; Dearry, Allen

    2014-12-01

    A joint US-EU workshop on enhancing data sharing and exchange in toxicogenomics was held at the National Institute for Environmental Health Sciences. Currently, efficient reuse of data is hampered by problems related to public data availability, data quality, database interoperability (the ability to exchange information), standardization and sustainability. At the workshop, experts from universities and research institutes presented databases, studies, organizations and tools that attempt to deal with these problems. Furthermore, a case study showing that combining toxicogenomics data from multiple resources leads to more accurate predictions in risk assessment was presented. All participants agreed that there is a need for a web portal describing the diverse, heterogeneous data resources relevant for toxicogenomics research. Furthermore, there was agreement that linking more data resources would improve toxicogenomics data analysis. To outline a roadmap to enhance interoperability between data resources, the participants recommend collecting user stories from the toxicogenomics research community on barriers in data sharing and exchange currently hampering answering to certain research questions. These user stories may guide the prioritization of steps to be taken for enhancing integration of toxicogenomics databases.

  18. 高校科研管理系统数据库设计与实现%Design and Realization of University Scientific Research Management System Database

    Institute of Scientific and Technical Information of China (English)

    李海生; 李春青

    2014-01-01

    数据库设计是科研管理系统设计的核心,该文从数据库表的创建、SQL Server数据库关键技术的应用、数据库用户安全性管理、ADO.NET数据库访问技术和SQL Server数据库连接5个方面阐述高校科研管理系统数据库的设计与实现。%The database design is the core of the scientific research management system design, this article from the establishment of database tables, SQL Server database key technology application, the database user security management, ADO.NET database access technology and SQL Server database connection with the 5 aspects of the university scientific research management system design and implementation of the database.

  19. The National Hospital Discharge Survey and Nationwide Inpatient Sample: the databases used affect results in THA research.

    Science.gov (United States)

    Bekkers, Stijn; Bot, Arjan G J; Makarawung, Dennis; Neuhaus, Valentin; Ring, David

    2014-11-01

    The National Hospital Discharge Survey (NHDS) and the Nationwide Inpatient Sample (NIS) collect sample data and publish annual estimates of inpatient care in the United States, and both are commonly used in orthopaedic research. However, there are important differences between the databases, and because of these differences, asking these two databases the same question may result in different answers. The degree to which this is true for arthroplasty-related research has, to our knowledge, not been characterized. We tested the following null hypotheses: (1) there are no differences between the NHDS and NIS in patient characteristics, comorbidities, and adverse events in patients with hip osteoarthritis treated with THA, and (2) there are no differences between databases in factors associated with inpatient mortality, adverse events, and length of hospital stay after THA. The NHDS and NIS databases use different methods of data collection and weighting to provide data representative of all nonfederal hospital discharges in the United States. In 2006 the NHDS database contained 203,149 patients with hip arthritis treated with hip arthroplasty, and the NIS database included 193,879 patients. Multivariable analyses for factors associated with inpatient mortality, adverse events, and days of care were constructed for each database. We found that 26 of 42 of the factors in demographics, comorbidities, and adverse events after THA in the NIS and NHDS databases differed more than 10%. Age and days of care were associated with inpatient mortality with the NHDS and the NIS although the effect rates differ more than 10%. The NIS identified seven other factors not identified by the NHDS: wound complications, congestive heart failure, new mental disorder, chronic pulmonary disease, dementia, geographic region Northeast, acute postoperative anemia, and sex, that were associated with inpatient mortality even after controlling for potentially confounding variables. For inpatient

  20. Monitoring Urban Tree Cover Using Object-Based Image Analysis and Public Domain Remotely Sensed Data

    Directory of Open Access Journals (Sweden)

    Meghan Halabisky

    2011-10-01

    Full Text Available Urban forest ecosystems provide a range of social and ecological services, but due to the heterogeneity of these canopies their spatial extent is difficult to quantify and monitor. Traditional per-pixel classification methods have been used to map urban canopies, however, such techniques are not generally appropriate for assessing these highly variable landscapes. Landsat imagery has historically been used for per-pixel driven land use/land cover (LULC classifications, but the spatial resolution limits our ability to map small urban features. In such cases, hyperspatial resolution imagery such as aerial or satellite imagery with a resolution of 1 meter or below is preferred. Object-based image analysis (OBIA allows for use of additional variables such as texture, shape, context, and other cognitive information provided by the image analyst to segment and classify image features, and thus, improve classifications. As part of this research we created LULC classifications for a pilot study area in Seattle, WA, USA, using OBIA techniques and freely available public aerial photography. We analyzed the differences in accuracies which can be achieved with OBIA using multispectral and true-color imagery. We also compared our results to a satellite based OBIA LULC and discussed the implications of per-pixel driven vs. OBIA-driven field sampling campaigns. We demonstrated that the OBIA approach can generate good and repeatable LULC classifications suitable for tree cover assessment in urban areas. Another important finding is that spectral content appeared to be more important than spatial detail of hyperspatial data when it comes to an OBIA-driven LULC.

  1. SU-E-P-26: Oncospace: A Shared Radiation Oncology Database System Designed for Personalized Medicine, Decision Support, and Research

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, M; Robertson, S; Moore, J; Wong, J; DeWeese, T; McNutt, T [Johns Hopkins University, Baltimore, MD (United States); Phillips, M [Univ Washington, Seattle, WA (United States); Hendrickson, K [University of Washington, Seattle, WA (United States); Song, W; Kwok, P [Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, U of T, Toronto, Ontario (Canada)

    2015-06-15

    Purpose: Advancement in Radiation Oncology (RO) practice develops through evidence based medicine and clinical trial. Knowledge usable for treatment planning, decision support and research is contained in our clinical data, stored in an Oncospace database. This data store and the tools for populating and analyzing it are compatible with standard RO practice and are shared with collaborating institutions. The question is - what protocol for system development and data sharing within an Oncospace Consortium? We focus our example on the technology and data meaning necessary to share across the Consortium. Methods: Oncospace consists of a database schema, planning and outcome data import and web based analysis tools.1) Database: The Consortium implements a federated data store; each member collects and maintains its own data within an Oncospace schema. For privacy, PHI is contained within a single table, accessible to the database owner.2) Import: Spatial dose data from treatment plans (Pinnacle or DICOM) is imported via Oncolink. Treatment outcomes are imported from an OIS (MOSAIQ).3) Analysis: JHU has built a number of webpages to answer analysis questions. Oncospace data can also be analyzed via MATLAB or SAS queries.These materials are available to Consortium members, who contribute enhancements and improvements. Results: 1) The Oncospace Consortium now consists of RO centers at JHU, UVA, UW and the University of Toronto. These members have successfully installed and populated Oncospace databases with over 1000 patients collectively.2) Members contributing code and getting updates via SVN repository. Errors are reported and tracked via Redmine. Teleconferences include strategizing design and code reviews.3) Successfully remotely queried federated databases to combine multiple institutions’ DVH data for dose-toxicity analysis (see below – data combined from JHU and UW Oncospace). Conclusion: RO data sharing can and has been effected according to the Oncospace

  2. The U.S. Dairy Forage Research Center (USDFRC) condensed tannin NMR database

    Science.gov (United States)

    This perspective describes a solution-state NMR database for flavan-3-ol monomers and condensed tannin dimers through tetramers obtained from the literature to 2015, containing data searchable by structure, molecular formula, degrees of polymerization, 1H and 13C chemical shifts of the condensed tan...

  3. D Digital Model Database Applied to Conservation and Research of Wooden Construction in China

    Science.gov (United States)

    Zheng, Y.

    2013-07-01

    Protected by the Tai-Hang Mountains, Shanxi Province, located in north central China, is a highly prosperous, densely populated valley and considered to be one of the cradles of Chinese civilization. Its continuous habitation and rich culture have given rise to a large number of temple complexes and pavilions. Among these structures, 153 can be dated as early as from the Tang dynasty (618- 907C.E.) to the end of the Yuan dynasty (1279-1368C.E.) in Southern Shanxi area. The buildings are the best-preserved examples of wooden Chinese architecture in existence, exemplifying historic building technology and displaying highly intricate architectural decoration and detailing. They have survived war, earthquakes, and, in the last hundred years, neglect. In 2005, a decade-long conservation project was initiated by the State Administration of Cultural Heritage of China (SACH) to conserve and document these important buildings. The conservation process requires stabilization, conservation of important features, and, where necessary, partial dismantlement in order to replace unsound structural elements. Project team of CHCC have developed a practical recording system that created a record of all building components prior to and during the conservation process. After that we are trying to establish a comprehensive database which include all of the 153 earlier buildings, through which we can easily entering, browse, indexing information of the wooden construction, even deep into component details. The Database can help us to carry out comparative studies of these wooden structures, and, provide important support for the continued conservation of these heritage buildings. For some of the most important wooden structure, we have established three-dimensional models. Connected the Database with 3D Digital Model based on ArcGIS, we have developed 3D Digital Model Database for these cherish buildings. The 3D Digital Model Database helps us set up an integrate information inventory

  4. Active Databases & Their Research Status%主动数据库及其研究现状

    Institute of Scientific and Technical Information of China (English)

    梁雯

    2001-01-01

    The similarities and differences between an active database and a traditional database are expounded. The general model of an active database and the model of the Active Database Management System are discussed. In the light of the deficiencies of the object-oriented database, the paper probes into the superiorities of combining the active database with the object-oriented database. It also discusses the present situation and the development of the active database as well as the problems to be solved.

  5. A plant resource and experiment management system based on the Golm Plant Database as a basic tool for omics research

    Directory of Open Access Journals (Sweden)

    Selbig Joachim

    2008-05-01

    names generated by the system and barcode labels facilitate identification and management of the material. Web pages are provided as user interfaces to facilitate maintaining the system in an environment with many desktop computers and a rapidly changing user community. Web based search tools are the basis for joint use of the material by all researchers of the institute. Conclusion The Golm Plant Database system, which is based on a relational database, collects the genetic and environmental information on plant material during its production or experimental use at the Max-Planck-Institute of Molecular Plant Physiology. It thus provides information according to the MIAME standard for the component 'Sample' in a highly standardised format. The Plant Database system thus facilitates collaborative work and allows efficient queries in data analysis for systems biology research.

  6. Establishment of database and network for research of stream generator and state of the art technology review

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jae Bong; Hur, Nam Su; Moon, Seong In; Seo, Hyeong Won; Park, Bo Kyu; Park, Sung Ho; Kim, Hyung Geun [Sungkyunkwan Univ., Seoul (Korea, Republic of)

    2004-02-15

    A significant number of steam generator tubes are defective and are removed from service or repaired world widely. This wide spread damage has been caused by diverse degradation mechanisms, some of which are difficult to detect and predict. Regarding domestic nuclear power plants, also, the increase of number of operating nuclear power plants and operating periods may result in the increase of steam generator tube failure. So, it is important to carry out the integrity evaluation process to prevent the steam generator tube damage. There are two objectives of this research. The one is to make database for the research of steam generator at domestic research institution. It will increase the efficiency and capability of limited domestic research resources by sharing data and information through network organization. Also, it will enhance the current standard of integrity evaluation procedure that is considerably conservative but can be more reasonable. The second objective is to establish the standard integrity evaluation procedure for steam generator tube by reviewing state of the art technology. The research resources related to steam generator tubes are managed by the established web-based database system. The following topics are covered in this project: development of web-based network for research on steam generator tubes review of state of the art technology.

  7. The Danish Ventral Hernia Database - a valuable tool for quality assessment and research

    DEFF Research Database (Denmark)

    Helgstrand, Frederik; Jorgensen, Lars Nannestad

    2016-01-01

    AIM: The Danish Ventral Hernia Database (DVHD) provides national surveillance of current surgical practice and clinical postoperative outcomes. The intention is to reduce postoperative morbidity and hernia recurrence, evaluate new treatment strategies, and facilitate nationwide implementation...... of evidence-based treatment strategies. This paper describes the design and purpose of DVHD. STUDY POPULATION: Adult (≥18 years) patients with a Danish Civil Registration Number and undergoing surgery under elective or emergency conditions for ventral hernia in a Danish surgical department from 2007...... of operations and is an excellent tool for observing changes over time, including adjustment of several confounders. This national database registry has impacted on clinical practice in Denmark and led to a high number of scientific publications in recent years....

  8. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    NARCIS (Netherlands)

    Skripcak, T.; Belka, C.; Bosch, W.; Brink, C. Van den; Brunner, T.; Budach, V.; Büttner, D.; Debus, J.; Dekker, A.; Grau, C.; Gulliford, S.; Hurkmans, C.; Just, U.; Krause, M.; Lambin, P.; Langendijk, J.A.; Lewensohn, R.; Luhr, A.; Maingon, P.; Masucci, M.; Niyazi, M.; Poortmans, P.M.P.; Simon, M.; Schmidberger, H.; Spezi, E.; Stuschke, M.; Valentini, V.; Verheij, M.; Whitfield, G.; Zackrisson, B.; Zips, D.; Baumann, M.

    2014-01-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research

  9. Creating a data exchange strategy for radiotherapy research : Towards federated databases and anonymised public datasets

    NARCIS (Netherlands)

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Buettner, Daniel; Debus, Juergen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A.; Lewensohn, Rolf; Luehr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Bjoern; Zips, Daniel; Baumann, Michael

    2014-01-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate 'translational research

  10. Creating a data exchange strategy for radiotherapy research : Towards federated databases and anonymised public datasets

    NARCIS (Netherlands)

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Buettner, Daniel; Debus, Juergen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A.; Lewensohn, Rolf; Luehr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Bjoern; Zips, Daniel; Baumann, Michael

    2014-01-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate 'translational research

  11. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    NARCIS (Netherlands)

    Skripcak, T.; Belka, C.; Bosch, W.; Brink, C. Van den; Brunner, T.; Budach, V.; Büttner, D.; Debus, J.; Dekker, A.; Grau, C.; Gulliford, S.; Hurkmans, C.; Just, U.; Krause, M.; Lambin, P.; Langendijk, J.A.; Lewensohn, R.; Luhr, A.; Maingon, P.; Masucci, M.; Niyazi, M.; Poortmans, P.M.P.; Simon, M.; Schmidberger, H.; Spezi, E.; Stuschke, M.; Valentini, V.; Verheij, M.; Whitfield, G.; Zackrisson, B.; Zips, D.; Baumann, M.

    2014-01-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research

  12. A Hypervelocity Experimental Research Database (HERD): Support for the Wright Laboratory Armament Directorate Code Validation Program (COVAL)

    Science.gov (United States)

    Mullin, Scott A.; Anderson, Charles E., Jr.; Hertel, Eugene S., Jr.; Hunt, Ronald D.

    The Hypervelocity Experimental Research Database (HERD) described in this paper was developed to aid researchers with code validation for impacts that occur at velocities faster than the testable regime. Codes of concern include both hydrocodes and fast-running analytical or semi-empirical models used to predict the impact phenomenology and damage that results to projectiles and targets. There are several well documented experimental programs that can serve as benchmarks for code validation; these are identified and described. Recommendations for further experimentation (a canonical problem) to provide validation data are also discussed.

  13. What can we learn from a decade of database audits? The Duke Clinical Research Institute experience, 1997--2006.

    Science.gov (United States)

    Rostami, Reza; Nahm, Meredith; Pieper, Carl F

    2009-04-01

    Despite a pressing and well-documented need for better sharing of information on clinical trials data quality assurance methods, many research organizations remain reluctant to publish descriptions of and results from their internal auditing and quality assessment methods. We present findings from a review of a decade of internal data quality audits performed at the Duke Clinical Research Institute, a large academic research organization that conducts data management for a diverse array of clinical studies, both academic and industry-sponsored. In so doing, we hope to stimulate discussions that could benefit the wider clinical research enterprise by providing insight into methods of optimizing data collection and cleaning, ultimately helping patients and furthering essential research. We present our audit methodologies, including sampling methods, audit logistics, sample sizes, counting rules used for error rate calculations, and characteristics of audited trials. We also present database error rates as computed according to two analytical methods, which we address in detail, and discuss the advantages and drawbacks of two auditing methods used during this 10-year period. Our review of the DCRI audit program indicates that higher data quality may be achieved from a series of small audits throughout the trial rather than through a single large database audit at database lock. We found that error rates trended upward from year to year in the period characterized by traditional audits performed at database lock (1997-2000), but consistently trended downward after periodic statistical process control type audits were instituted (2001-2006). These increases in data quality were also associated with cost savings in auditing, estimated at 1000 h per year, or the efforts of one-half of a full time equivalent (FTE). Our findings are drawn from retrospective analyses and are not the result of controlled experiments, and may therefore be subject to unanticipated confounding

  14. What can we learn from a decade of database audits? The Duke Clinical Research Institute experience, 1997–2006

    Science.gov (United States)

    Rostami, Reza; Nahm, Meredith; Pieper, Carl F.

    2011-01-01

    Background Despite a pressing and well-documented need for better sharing of information on clinical trials data quality assurance methods, many research organizations remain reluctant to publish descriptions of and results from their internal auditing and quality assessment methods. Purpose We present findings from a review of a decade of internal data quality audits performed at the Duke Clinical Research Institute, a large academic research organization that conducts data management for a diverse array of clinical studies, both academic and industry-sponsored. In so doing, we hope to stimulate discussions that could benefit the wider clinical research enterprise by providing insight into methods of optimizing data collection and cleaning, ultimately helping patients and furthering essential research. Methods We present our audit methodologies, including sampling methods, audit logistics, sample sizes, counting rules used for error rate calculations, and characteristics of audited trials. We also present database error rates as computed according to two analytical methods, which we address in detail, and discuss the advantages and drawbacks of two auditing methods used during this ten-year period. Results Our review of the DCRI audit program indicates that higher data quality may be achieved from a series of small audits throughout the trial rather than through a single large database audit at database lock. We found that error rates trended upward from year to year in the period characterized by traditional audits performed at database lock (1997–2000), but consistently trended downward after periodic statistical process control type audits were instituted (2001–2006). These increases in data quality were also associated with cost savings in auditing, estimated at 1000 hours per year, or the efforts of one-half of a full time equivalent (FTE). Limitations Our findings are drawn from retrospective analyses and are not the result of controlled experiments, and

  15. A nonsurgical endodontics relational research database: the initial six years of experience.

    Science.gov (United States)

    Iqbal, Mian K; Shukovsky, Deborah Gortler; Wong, Steven; Vohra, Gayatri

    2008-09-01

    The purpose of this study was to report results of the initial six years of experience utilizing a nonsurgical root canal treatment (NSRCT) database; to compare patient characteristics, operative procedures, and patient outcomes observed in the database to those observed in other studies; and to discuss the potential benefits of a clinical endodontic database. A total of 7,372 NSRCT cases performed by endodontic residents at the University of Pennsylvania from 2000 to 2006 were evaluated. The odds ratio (OR) for caries and trauma being causative agents for NSRCT in

  16. Mapping the Iranian Research Literature in the Field of Traditional Medicine in Scopus Database 2010-2014.

    Science.gov (United States)

    GhaedAmini, Hossein; Okhovati, Maryam; Zare, Morteza; Saghafi, Zahra; Bazrafshan, Azam; GhaedAmini, Alireza; GhaedAmini, Mohammadreza

    2016-05-01

    The aim of this study was to provide research and collaboration overview of Iranian research efforts in the field of traditional medicine during 2010-2014. This is a bibliometric study using the Scopus database as data source, using search affiliation address relevant to traditional medicine and Iran as the search strategy. Subject and geographical overlay maps were also applied to visualize the network activities of the Iranian authors. Highly cited articles (citations >10) were further explored to highlight the impact of research domains more specifically. About 3,683 articles were published by Iranian authors in Scopus database. The compound annual growth rate of Iranian publications was 0.14% during 2010-2014. Tehran University of Medical Sciences (932 articles), Shiraz University of Medical Sciences (404 articles) and Tabriz Islamic Medical University (391 articles), were the leading institutions in the field of traditional medicine. Medicinal plants (72%), digestive system's disease (21%), basics of traditional medicine (13%), mental disorders (8%) were the major research topics. United States (7%), Netherlands (3%), and Canada (2.6%) were the most important collaborators of Iranian authors. Iranian research efforts in the field of traditional medicine have been increased slightly over the last years. Yet, joint multi-disciplinary collaborations are needed to cover inadequately described areas of traditional medicine in the country.

  17. Use of media and public-domain Internet sources for detection and assessment of plant health threats

    Directory of Open Access Journals (Sweden)

    David M. Hartley

    2011-09-01

    Full Text Available Event-based biosurveillance is a recognized approach to early warning and situational awareness of emerging health threats. In this study, we build upon previous human and animal health work to develop a new approach to plant pest and pathogen surveillance. We show that monitoring public domain electronic media for indications and warning of epidemics and associated social disruption can provide information about the emergence and progression of plant pest infestation or disease outbreak. The approach is illustrated using a case study, which describes a plant pest and pathogen epidemic in China and Vietnam from February 2006 to December 2007, and the role of ducks in contributing to zoonotic virus spread in birds and humans. This approach could be used as a complementary method to traditional plant pest and pathogen surveillance to aid global and national plant protection officials and political leaders in early detection and timely response to significant biological threats to plant health, economic vitality, and social stability. This study documents the inter-relatedness of health in human, animal, and plant populations and emphasizes the importance of plant health surveillance.

  18. Development of prostate cancer research database with the clinical data warehouse technology for direct linkage with electronic medical record system.

    Science.gov (United States)

    Choi, In Young; Park, Seungho; Park, Bumjoon; Chung, Byung Ha; Kim, Choung-Soo; Lee, Hyun Moo; Byun, Seok-Soo; Lee, Ji Youl

    2013-01-01

    In spite of increased prostate cancer patients, little is known about the impact of treatments for prostate cancer patients and outcome of different treatments based on nationwide data. In order to obtain more comprehensive information for Korean prostate cancer patients, many professionals urged to have national system to monitor the quality of prostate cancer care. To gain its objective, the prostate cancer database system was planned and cautiously accommodated different views from various professions. This prostate cancer research database system incorporates information about a prostate cancer research including demographics, medical history, operation information, laboratory, and quality of life surveys. And, this system includes three different ways of clinical data collection to produce a comprehensive data base; direct data extraction from electronic medical record (EMR) system, manual data entry after linking EMR documents like magnetic resonance imaging findings and paper-based data collection for survey from patients. We implemented clinical data warehouse technology to test direct EMR link method with St. Mary's Hospital system. Using this method, total number of eligible patients were 2,300 from 1997 until 2012. Among them, 538 patients conducted surgery and others have different treatments. Our database system could provide the infrastructure for collecting error free data to support various retrospective and prospective studies.

  19. How Large Is the "Public Domain"? A Comparative Analysis of Ringer's 1961 Copyright Renewal Study and HathiTrust CRMS Data

    Science.gov (United States)

    Wilkin, John P.

    2017-01-01

    The 1961 Copyright Office study on renewals, authored by Barbara Ringer, has cast an outsized influence on discussions of the U.S. 1923-1963 public domain. As more concrete data emerge from initiatives such as the large-scale determination process in the Copyright Review Management System (CRMS) project, questions are raised about the reliability…

  20. 41 CFR 102-75.100 - When an agency holds land withdrawn or reserved from the public domain and determines that it no...

    Science.gov (United States)

    2010-07-01

    ... land withdrawn or reserved from the public domain and determines that it no longer needs this land, what must it do? 102-75.100 Section 102-75.100 Public Contracts and Property Management Federal... it no longer needs this land, what must it do? An agency holding unneeded land withdrawn or...

  1. Construction of a rice glycoside hydrolase phylogenomic database and identification of targets for biofuel research

    Directory of Open Access Journals (Sweden)

    Rita eSharma

    2013-08-01

    Full Text Available Glycoside hydrolases (GH catalyze the hydrolysis of glycosidic bonds in cell wall polymers and can have major effects on cell wall architecture. Taking advantage of the massive datasets available in public databases, we have constructed a rice phylogenomic database of GHs (http://ricephylogenomics.ucdavis.edu/cellwalls/gh/. This database integrates multiple data types including the structural features, orthologous relationships, mutant availability and gene expression patterns for each GH family in a phylogenomic context. The rice genome encodes 437 GH genes classified into 34 families. Based on pairwise comparison with eight dicot and four monocot genomes, we identified 138 GH genes that are highly diverged between monocots and dicots, 57 of which have diverged further in rice as compared with four monocot genomes scanned in this study. Chromosomal localization and expression analysis suggest a role for both whole-genome and localized gene duplications in expansion and diversification of GH families in rice. We examined the meta-profiles of expression patterns of GH genes in twenty different anatomical tissues of rice. Transcripts of 51 genes exhibit tissue or developmental stage-preferential expression, whereas, seventeen other genes preferentially accumulate in actively growing tissues. When queried in RiceNet, a probabilistic functional gene network that facilitates functional gene predictions, nine out of seventeen genes form a regulatory network with the well-characterized genes involved in biosynthesis of cell wall polymers including cellulose synthase and cellulose synthase-like genes of rice. Two-thirds of the GH genes in rice are up regulated in response to biotic and abiotic stress treatments indicating a role in stress adaptation. Our analyses identify potential GH targets for cell wall modification.

  2. The Nordic prescription databases as a resource for pharmacoepidemiological research-a literature review

    DEFF Research Database (Denmark)

    Wettermark, B; Zoëga, H; Furu, K

    2013-01-01

    PURPOSE: All five Nordic countries have nationwide prescription databases covering all dispensed drugs, with potential for linkage to outcomes. The aim of this review is to present an overview of therapeutic areas studied and methods applied in pharmacoepidemiologic studies using data from...... in Norway, and 61 in Sweden. Four studies used data from more than one Nordic country. The most commonly studied drugs were those acting on the nervous system, followed by cardiovascular drugs and gastrointestinal/endocrine drugs. A total of 228 studies examined drug utilization and 263 focused...

  3. Biological Databases

    Directory of Open Access Journals (Sweden)

    Kaviena Baskaran

    2013-12-01

    Full Text Available Biology has entered a new era in distributing information based on database and this collection of database become primary in publishing information. This data publishing is done through Internet Gopher where information resources easy and affordable offered by powerful research tools. The more important thing now is the development of high quality and professionally operated electronic data publishing sites. To enhance the service and appropriate editorial and policies for electronic data publishing has been established and editors of article shoulder the responsibility.

  4. DMPD: Fifty years of interferon research: aiming at a moving target. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16979566 Fifty years of interferon research: aiming at a moving target. Vilcek J. I...mmunity. 2006 Sep;25(3):343-8. (.png) (.svg) (.html) (.csml) Show Fifty years of interferon research: aiming... at a moving target. PubmedID 16979566 Title Fifty years of interferon research: aiming at a moving target.

  5. Bibliometric analysis of nutrition and dietetics research activity in Arab countries using ISI Web of Science database.

    Science.gov (United States)

    Sweileh, Waleed M; Al-Jabi, Samah W; Sawalha, Ansam F; Zyoud, Sa'ed H

    2014-01-01

    Reducing nutrition-related health problems in Arab countries requires an understanding of the performance of Arab countries in the field of nutrition and dietetics research. Assessment of research activity from a particular country or region could be achieved through bibliometric analysis. This study was carried out to investigate research activity in "nutrition and dietetics" in Arab countries. Original and review articles published from Arab countries in "nutrition and dietetics" Web of Science category up until 2012 were retrieved and analyzed using the ISI Web of Science database. The total number of documents published in "nutrition and dietetics" category from Arab countries was 2062. This constitutes 1% of worldwide research activity in the field. Annual research productivity showed a significant increase after 2005. Approximately 60% of published documents originated from three Arab countries, particularly Egypt, Kingdom of Saudi Arabia, and Tunisia. However, Kuwait has the highest research productivity per million inhabitants. Main research areas of published documents were in "Food Science/Technology" and "Chemistry" which constituted 75% of published documents compared with 25% for worldwide documents in nutrition and dietetics. A total of 329 (15.96%) nutrition - related diabetes or obesity or cancer documents were published from Arab countries compared with 21% for worldwide published documents. Interest in nutrition and dietetics research is relatively recent in Arab countries. Focus of nutrition research is mainly toward food technology and chemistry with lesser activity toward nutrition-related health research. International cooperation in nutrition research will definitely help Arab researchers in implementing nutrition research that will lead to better national policies regarding nutrition.

  6. Estimating and modelling bias of the hierarchical partitioning public-domain software: implications in environmental management and conservation.

    Directory of Open Access Journals (Sweden)

    Pedro P Olea

    Full Text Available BACKGROUND: Hierarchical partitioning (HP is an analytical method of multiple regression that identifies the most likely causal factors while alleviating multicollinearity problems. Its use is increasing in ecology and conservation by its usefulness for complementing multiple regression analysis. A public-domain software "hier.part package" has been developed for running HP in R software. Its authors highlight a "minor rounding error" for hierarchies constructed from >9 variables, however potential bias by using this module has not yet been examined. Knowing this bias is pivotal because, for example, the ranking obtained in HP is being used as a criterion for establishing priorities of conservation. METHODOLOGY/PRINCIPAL FINDINGS: Using numerical simulations and two real examples, we assessed the robustness of this HP module in relation to the order the variables have in the analysis. Results indicated a considerable effect of the variable order on the amount of independent variance explained by predictors for models with >9 explanatory variables. For these models the nominal ranking of importance of the predictors changed with variable order, i.e. predictors declared important by its contribution in explaining the response variable frequently changed to be either most or less important with other variable orders. The probability of changing position of a variable was best explained by the difference in independent explanatory power between that variable and the previous one in the nominal ranking of importance. The lesser is this difference, the more likely is the change of position. CONCLUSIONS/SIGNIFICANCE: HP should be applied with caution when more than 9 explanatory variables are used to know ranking of covariate importance. The explained variance is not a useful parameter to use in models with more than 9 independent variables. The inconsistency in the results obtained by HP should be considered in future studies as well as in those

  7. The Energy Science and Technology Database on a local library system: A case study at the Los Alamos National Research Library

    Energy Technology Data Exchange (ETDEWEB)

    Holtkamp, I.S.

    1994-10-01

    This paper presents an overview of efforts at Los Alamos National Laboratory to acquire and mount the Energy Science and Technology Database (EDB) as a citation database on the Research Library`s Geac Advance system. The rationale for undertaking this project and expected benefits are explained. Significant issues explored are loading non-USMARC records into a MARC-based library system, the use of EDB records to replace or supplement in-house cataloging of technical reports, the impact of different cataloging standards and database size on searching and retrieval, and how integrating an external database into the library`s online catalog may affect staffing and workflow.

  8. BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.

    Science.gov (United States)

    Howe, E A; de Souza, A; Lahr, D L; Chatwin, S; Montgomery, P; Alexander, B R; Nguyen, D-T; Cruz, Y; Stonich, D A; Walzer, G; Rose, J T; Picard, S C; Liu, Z; Rose, J N; Xiang, X; Asiedu, J; Durkin, D; Levine, J; Yang, J J; Schürer, S C; Braisted, J C; Southall, N; Southern, M R; Chung, T D Y; Brudz, S; Tanega, C; Schreiber, S L; Bittker, J A; Guha, R; Clemons, P A

    2015-01-01

    BARD, the BioAssay Research Database (https://bard.nih.gov/) is a public database and suite of tools developed to provide access to bioassay data produced by the NIH Molecular Libraries Program (MLP). Data from 631 MLP projects were migrated to a new structured vocabulary designed to capture bioassay data in a formalized manner, with particular emphasis placed on the description of assay protocols. New data can be submitted to BARD with a user-friendly set of tools that assist in the creation of appropriately formatted datasets and assay definitions. Data published through the BARD application program interface (API) can be accessed by researchers using web-based query tools or a desktop client. Third-party developers wishing to create new tools can use the API to produce stand-alone tools or new plug-ins that can be integrated into BARD. The entire BARD suite of tools therefore supports three classes of researcher: those who wish to publish data, those who wish to mine data for testable hypotheses, and those in the developer community who wish to build tools that leverage this carefully curated chemical biology resource.

  9. A three dimensional children head database for acoustical research and development

    DEFF Research Database (Denmark)

    Harder, Stine; Paulsen, Rasmus Reinhold; Larsen, Martin;

    2013-01-01

    . The process consists of a regularized surface reconstruction step followed by an alignment step. Finally, a surface representation of the entire head is extracted using a triangulation of the zero-level iso-surface of the implicit volume. The process has been used to reconstruct the heads of children aged 10......Most computational-acoustic work within spatial hearing relies on head-related transfer functions from databases of measurements taken on adult humans or dummy heads. We aim to provide a set of 3D digital heads including children, from which head-related transfer functions can be computed instead...... by acquisition of multiple 3D surface scans of the same subject using a high-resolution photogrammetric scanner. Secondly, the scans are semi-automatically aligned and noise and incoherence is removed. This is followed by an iterative process where a volumetric implicit representation of the head is optimized...

  10. Research on the J2EE-based product database management system

    Institute of Scientific and Technical Information of China (English)

    LIN Lin; YAO Yu; ZHONG Shi-sheng

    2007-01-01

    The basic frame and the design idea of J2EE-based Product Data Management (PDM) system are presented. This paper adopts the technology of Object-Oriented to realize the database design and builds the information model of this PDM system. The integration key technology of PDM and CAD systems are discussed,the isomerous interface characteristics between CAD and PDM systems are analyzed, and finally, the integration mode of the PDM and CAD systems is given. Using these technologies, the integration of PDM and CAD systems is realized and the consistence of data in PDM and CAD systems is kept. Finally, the Product Data Management system is developed, which has been tested on development process of the hydraulic generator. The running process is stable and safety.

  11. Review of 130 years of research on cyanobacteria in aquatic ecosystems in Serbia presented in a Serbian Cyanobacterial Database

    Directory of Open Access Journals (Sweden)

    Zorica Svirčev

    2017-05-01

    Full Text Available The presence of toxic cyanobacteria in aquatic ecosystems in the territory of the Republic of Serbia was surveyed over a period of several decades. Increasing attention is being paid to some negative consequences that may be caused by these microorganisms. Information from available literary sources regarding the distribution and frequency of cyanobacteria and their toxins over a period of 130 years, together with the effects on humans and wildlife in aquatic ecosystems, were gathered and incorporated into a Serbian Cyanobacterial Database created for the CYANOCOST Action. This database encompasses information on 65 aquatic ecosystems, including rivers, lakes, ponds, canals, irrigation reservoirs, reservoirs used for drinking water supply and reservoirs used for other purposes. Cyanobacterial blooms were found in almost 80% of the investigated aquatic ecosystems. The analysis of the research showed the presence of more than 70 species, including blooms of 24 species from 13 genera. Five species of cyanobacteria: Microcystis aeruginosa, Aphanizomenon flos-aquae, Planktothrix agardhii, Microcystis flos-aquae and Planktothrix rubescens frequently formed blooms in the investigated waterbodies and cyanotoxins were also detected in some of them, which had certain negative effects. Here, we present an overview of data contained in the Serbian Cyanobacterial Database, concerning cyanobacterial distribution, cyanotoxin production and associated biological effects in different types of water bodies from the Republic of Serbia. Also, recent important and major cases of cyanobacterial blooming in reservoirs used for drinking water supply: at Vrutci and Ćelije, the Aleksandrovac irrigation reservoir, the Ponjavica River and Lake Palić, including systematic research on the Lake Ludoš and few fishponds are further described. It can be concluded that cyanobacteria and cyanotoxins are omnipresent in different water bodies throughout the Republic of Serbia

  12. A spatial classification and database for management, research, and policy making: The Great Lakes aquatic habitat framework

    Science.gov (United States)

    Wang, Lizhu; Riseng, Catherine M.; Mason, Lacey; Werhrly, Kevin; Rutherford, Edward; McKenna, James E.; Castiglione, Chris; Johnson, Lucinda B.; Infante, Dana M.; Sowa, Scott P.; Robertson, Mike; Schaeffer, Jeff; Khoury, Mary; Gaiot, John; Hollenhurst, Tom; Brooks, Colin N.; Coscarelli, Mark

    2015-01-01

    Managing the world's largest and most complex freshwater ecosystem, the Laurentian Great Lakes, requires a spatially hierarchical basin-wide database of ecological and socioeconomic information that is comparable across the region. To meet such a need, we developed a spatial classification framework and database — Great Lakes Aquatic Habitat Framework (GLAHF). GLAHF consists of catchments, coastal terrestrial, coastal margin, nearshore, and offshore zones that encompass the entire Great Lakes Basin. The catchments captured in the database as river pour points or coastline segments are attributed with data known to influence physicochemical and biological characteristics of the lakes from the catchments. The coastal terrestrial zone consists of 30-m grid cells attributed with data from the terrestrial region that has direct connection with the lakes. The coastal margin and nearshore zones consist of 30-m grid cells attributed with data describing the coastline conditions, coastal human disturbances, and moderately to highly variable physicochemical and biological characteristics. The offshore zone consists of 1.8-km grid cells attributed with data that are spatially less variable compared with the other aquatic zones. These spatial classification zones and their associated data are nested within lake sub-basins and political boundaries and allow the synthesis of information from grid cells to classification zones, within and among political boundaries, lake sub-basins, Great Lakes, or within the entire Great Lakes Basin. This spatially structured database could help the development of basin-wide management plans, prioritize locations for funding and specific management actions, track protection and restoration progress, and conduct research for science-based decision making.

  13. Database Urban Europe

    NARCIS (Netherlands)

    Sleutjes, B.; de Valk, H.A.G.

    2016-01-01

    Database Urban Europe: ResSegr database on segregation in The Netherlands. Collaborative research on residential segregation in Europe 2014–2016 funded by JPI Urban Europe (Joint Programming Initiative Urban Europe).

  14. A meta-database comparison from various European research networks dedicated to forests sites

    NARCIS (Netherlands)

    Danielewska, A.; Clarke, N.; Olejnik, J.; Hansen, K.; Vries, de W.

    2013-01-01

    Of a wide variety of international forest research and monitoring networks, several networks are dedicated to the effects of climate change on forests, while the effects of anthropogenic pollutants on forests have been a major area for both monitoring and research for decades. The large amounts of d

  15. Government databases and public health research: facilitating access in the public interest.

    Science.gov (United States)

    Adams, Carolyn; Allen, Judy

    2014-06-01

    Access to datasets of personal health information held by government agencies is essential to support public health research and to promote evidence-based public health policy development. Privacy legislation in Australia allows the use and disclosure of such information for public health research. However, access is not always forthcoming in a timely manner and the decision-making process undertaken by government data custodians is not always transparent. Given the public benefit in research using these health information datasets, this article suggests that it is time to recognise a right of access for approved research and that the decisions, and decision-making processes, of government data custodians should be subject to increased scrutiny. The article concludes that researchers should have an avenue of external review where access to information has been denied or unduly delayed.

  16. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    DEFF Research Database (Denmark)

    Skripcak, Tomas; Belka, Claus; Bosch, Walter

    2014-01-01

    for knowledge generation within “Big Data“. Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning...... to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data......Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research...

  17. In search of yoga: Research trends in a western medical database

    Directory of Open Access Journals (Sweden)

    Marcy C McCall

    2014-01-01

    Conclusions: The prevalence of yoga research in western healthcare is increasing. The marked increase in volume indicates the need for more systematic analysis of the literature in terms of quality and results.

  18. Maintaining the Database for Information Object Analysis, Intent, Dissemination and Enhancement (IOAIDE) and the US Army Research Laboratory Campus Sensor Network (ARL CSN)

    Science.gov (United States)

    2017-01-04

    ARL-TR-7921 ● JAN 2017 US Army Research Laboratory Maintaining the Database for Information Object Analysis , Intent...ARL-TR-7921 ● JAN 2017 US Army Research Laboratory Maintaining the Database for Information Object Analysis , Intent, Dissemination and...YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) January 2017 2. REPORT TYPE Technical Report 3. DATES COVERED (From - To) 4. TITLE

  19. [Research and development of medical case database: a novel medical case information system integrating with biospecimen management].

    Science.gov (United States)

    Pan, Shiyang; Mu, Yuan; Wang, Hong; Wang, Tong; Huang, Peijun; Ma, Jianfeng; Jiang, Li; Zhang, Jie; Gu, Bing; Yi, Lujiang

    2010-04-01

    To meet the needs of management of medical case information and biospecimen simultaneously, we developed a novel medical case information system integrating with biospecimen management. The database established by MS SQL Server 2000 covered, basic information, clinical diagnosis, imaging diagnosis, pathological diagnosis and clinical treatment of patient; physicochemical property, inventory management and laboratory analysis of biospecimen; users log and data maintenance. The client application developed by Visual C++ 6.0 was used to implement medical case and biospecimen management, which was based on Client/Server model. This system can perform input, browse, inquest, summary of case and related biospecimen information, and can automatically synthesize case-records based on the database. Management of not only a long-term follow-up on individual, but also of grouped cases organized according to the aim of research can be achieved by the system. This system can improve the efficiency and quality of clinical researches while biospecimens are used coordinately. It realizes synthesized and dynamic management of medical case and biospecimen, which may be considered as a new management platform.

  20. Automatic detection of lung nodules in computed tomography images: training and validation of algorithms using public research databases

    Science.gov (United States)

    Camarlinghi, Niccolò

    2013-09-01

    Lung cancer is one of the main public health issues in developed countries. Lung cancer typically manifests itself as non-calcified pulmonary nodules that can be detected reading lung Computed Tomography (CT) images. To assist radiologists in reading images, researchers started, a decade ago, the development of Computer Aided Detection (CAD) methods capable of detecting lung nodules. In this work, a CAD composed of two CAD subprocedures is presented: , devoted to the identification of parenchymal nodules, and , devoted to the identification of the nodules attached to the pleura surface. Both CADs are an upgrade of two methods previously presented as Voxel Based Neural Approach CAD . The novelty of this paper consists in the massive training using the public research Lung International Database Consortium (LIDC) database and on the implementation of new features for classification with respect to the original VBNA method. Finally, the proposed CAD is blindly validated on the ANODE09 dataset. The result of the validation is a score of 0.393, which corresponds to the average sensitivity of the CAD computed at seven predefined false positive rates: 1/8, 1/4, 1/2, 1, 2, 4, and 8 FP/CT.

  1. Research of Cadastral Data Modelling and Database Updating Based on Spatio-temporal Process

    Directory of Open Access Journals (Sweden)

    ZHANG Feng

    2016-02-01

    Full Text Available The core of modern cadastre management is to renew the cadastre database and keep its currentness,topology consistency and integrity.This paper analyzed the changes and their linkage of various cadastral objects in the update process.Combined object-oriented modeling technique with spatio-temporal objects' evolution express,the paper proposed a cadastral data updating model based on the spatio-temporal process according to people's thought.Change rules based on the spatio-temporal topological relations of evolution cadastral spatio-temporal objects are drafted and further more cascade updating and history back trace of cadastral features,land use and buildings are realized.This model implemented in cadastral management system-ReGIS.Achieved cascade changes are triggered by the direct driving force or perceived external events.The system records spatio-temporal objects' evolution process to facilitate the reconstruction of history,change tracking,analysis and forecasting future changes.

  2. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Jones Roy

    2011-10-01

    Full Text Available Abstract Background Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical community because of concerns that commercial, rather than scientific, goals are the primary purpose of such endeavours. Thus, there are few examples of sustained collaboration between leading academic clinical researchers and industry professionals in a large-scale data mining project. We present here a successful example of this type of collaboration in the field of dementia. Methods The Donepezil Data Repository comprised 18 randomised, controlled trials conducted between 1991 and 2005. The project team at Pfizer determined that the data mining process should be guided by a diverse group of leading Alzheimer's disease clinical researchers called the "Expert Working Group." After development of a list of potential faculty members, invitations were extended and a group of seven members was assembled. The Working Group met regularly with Eisai/Pfizer clinicians and statisticians to discuss the data, identify issues that were currently of interest in the academic and clinical communities that might lend themselves to investigation using these data, and note gaps in understanding or knowledge of Alzheimer's disease that these data could address. Leadership was provided by the Pfizer Clinical Development team leader; Working Group members rotated responsibility for being lead and co-lead for each investigation and resultant publication. Results Six manuscripts, each published in a leading subspecialty journal, resulted from the group's work. Another project resulted in poster presentations at international congresses and two were cancelled due to resource constraints. Conclusions The experience represents a particular approach to

  3. Assessing worldwide research activity on probiotics in pediatrics using Scopus database: 1994-2014.

    Science.gov (United States)

    Sweileh, Waleed M; Shraim, Naser Y; Al-Jabi, Samah W; Sawalha, Ansam F; Rahhal, Belal; Khayyat, Rasha A; Zyoud, Sa'ed H

    2016-01-01

    A wide variety of probiotic products has been introduced into the market in the past decade. Research trends and activity on probiotics help understand how these products were evolved and their potential future role in medicine. The objective of this study was to assess the research activity on probiotics in pediatrics using bibliometric indicators and network visualization. Original and review articles on probiotics in pediatrics published worldwide were retrieved from SciVerse, Scopus (1994-2014) and analyzed. VOSviewer was used for network visualization. The total number of documents published on probiotics in pediatrics was 2817. Research activity on probiotics in pediatrics showed approximately 90- fold increase during the study period. Approximately 22 % of published articles originated from USA and has the greatest share, however, Finland ranked first when data were stratified by population or income. The most productive institution in this field was Turku University in Finland with 82 (2.91 %) articles. Half of the prolific authors were also from Finland. Most of the published research activity appeared in Journal of Pediatric Gastroenterology and Nutrition. Most frequently encountered title terms include nutrition, infant formula, necrotizing enetrocolitis, allergy, and diarrhea. The total number of citations for the retreived documents documents was 70991, and the average citation per article was 25.20. Interest in probiotic research and its potential benefits in pediatric ailments is relatively recent but significantly increasing. Bibliometric analysis can be used as an indicator of the importance and growth of probiotic use in pediatrics.

  4. Designing and recruiting to UK autism spectrum disorder research databases: do they include representative children with valid ASD diagnoses?

    Science.gov (United States)

    Warnell, F; George, B; McConachie, H; Johnson, M; Hardy, R; Parr, J R

    2015-09-04

    (1) Describe how the Autism Spectrum Database-UK (ASD-UK) was established; (2) investigate the representativeness of the first 1000 children and families who participated, compared to those who chose not to; (3) investigate the reliability of the parent-reported Autism Spectrum Disorder (ASD) diagnoses, and present evidence about the validity of diagnoses, that is, whether children recruited actually have an ASD; (4) present evidence about the representativeness of the ASD-UK children and families, by comparing their characteristics with the first 1000 children and families from the regional Database of children with ASD living in the North East (Dasl(n)e), and children and families identified from epidemiological studies. Recruitment through a network of 50 UK child health teams and self-referral. Parents/carers with a child with ASD, aged 2-16 years, completed questionnaires about ASD and some gave professionals' reports about their children. 1000 families registered with ASD-UK in 30 months. Children of families who participated, and of the 208 who chose not to, were found to be very similar on: gender ratio, year of birth, ASD diagnosis and social deprivation score. The reliability of parent-reported ASD diagnoses of children was very high when compared with clinical reports (over 96%); no database child without ASD was identified. A comparison of gender, ASD diagnosis, age at diagnosis, school placement, learning disability, and deprivation score of children and families from ASD-UK with 1084 children and families from Dasl(n)e, and families from population studies, showed that ASD-UK families are representative of families of children with ASD overall. ASD-UK includes families providing parent-reported data about their child and family, who appear to be broadly representative of UK children with ASD. Families continue to join the databases and more than 3000 families can now be contacted by researchers about UK autism research. Published by the BMJ

  5. Neodymium in the oceans: a global database, a regional comparison and implications for palaeoceanographic research

    Science.gov (United States)

    van de Flierdt, Tina; Griffiths, Alexander M.; Lambelet, Myriam; Little, Susan H.; Stichel, Torben; Wilson, David J.

    2016-11-01

    The neodymium (Nd) isotopic composition of seawater has been used extensively to reconstruct ocean circulation on a variety of time scales. However, dissolved neodymium concentrations and isotopes do not always behave conservatively, and quantitative deconvolution of this non-conservative component can be used to detect trace metal inputs and isotopic exchange at ocean-sediment interfaces. In order to facilitate such comparisons for historical datasets, we here provide an extended global database for Nd isotopes and concentrations in the context of hydrography and nutrients. Since 2010, combined datasets for a large range of trace elements and isotopes are collected on international GEOTRACES section cruises, alongside classical nutrient and hydrography measurements. Here, we take a first step towards exploiting these datasets by comparing high-resolution Nd sections for the western and eastern North Atlantic in the context of hydrography, nutrients and aluminium (Al) concentrations. Evaluating those data in tracer-tracer space reveals that North Atlantic seawater Nd isotopes and concentrations generally follow the patterns of advection, as do Al concentrations. Deviations from water mass mixing are observed locally, associated with the addition or removal of trace metals in benthic nepheloid layers, exchange with ocean margins (i.e. boundary exchange) and/or exchange with particulate phases (i.e. reversible scavenging). We emphasize that the complexity of some of the new datasets cautions against a quantitative interpretation of individual palaeo Nd isotope records, and indicates the importance of spatial reconstructions for a more balanced approach to deciphering past ocean changes. This article is part of the themed issue 'Biological and climatic impacts of ocean trace element chemistry'.

  6. Gypsy moths: Pest control research. (Latest citations from the Life Sciences Collection database). Published Search

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    The bibliography contains citations concerning control and research regarding gypsy moths or lymantria dispar. Both natural and synthetic controls are discussed, including parasites, viral diseases, fungal diseases, bird predation, bacterial diseases, pheromone trapping, insecticides, and physical and chemical localized protection. Laboratory and field studies on sex pheromones, environmental effects on life cycles, effects of feeding behavior, plant-insect interactions, and other research relating to the control of this forest pest are considered. (Contains 250 citations and includes a subject term index and title list.)

  7. Combining Public Domain and Professional Panoramic Imagery for the Accurate and Dense 3d Reconstruction of the Destroyed Bel Temple in Palmyra

    Science.gov (United States)

    Wahbeh, W.; Nebiker, S.; Fangi, G.

    2016-06-01

    This paper exploits the potential of dense multi-image 3d reconstruction of destroyed cultural heritage monuments by either using public domain touristic imagery only or by combining the public domain imagery with professional panoramic imagery. The focus of our work is placed on the reconstruction of the temple of Bel, one of the Syrian heritage monuments, which was destroyed in September 2015 by the so called "Islamic State". The great temple of Bel is considered as one of the most important religious buildings of the 1st century AD in the East with a unique design. The investigations and the reconstruction were carried out using two types of imagery. The first are freely available generic touristic photos collected from the web. The second are panoramic images captured in 2010 for documenting those monuments. In the paper we present a 3d reconstruction workflow for both types of imagery using state-of-the art dense image matching software, addressing the non-trivial challenges of combining uncalibrated public domain imagery with panoramic images with very wide base-lines. We subsequently investigate the aspects of accuracy and completeness obtainable from the public domain touristic images alone and from the combination with spherical panoramas. We furthermore discuss the challenges of co-registering the weakly connected 3d point cloud fragments resulting from the limited coverage of the touristic photos. We then describe an approach using spherical photogrammetry as a virtual topographic survey allowing the co-registration of a detailed and accurate single 3d model of the temple interior and exterior.

  8. Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database

    Directory of Open Access Journals (Sweden)

    Kalathur Ravi Kiran

    2012-06-01

    Full Text Available Abstract Background Huntington’s disease (HD is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation of a single gene, intensive research has linked numerous other genes to its pathogenesis. To obtain a systematic overview of these genes, which may serve as therapeutic targets, CHDI Foundation has recently established the HD Research Crossroads database. With currently over 800 cataloged genes, this web-based resource constitutes the most extensive curation of genes relevant to HD. It provides us with an unprecedented opportunity to survey molecular mechanisms involved in HD in a holistic manner. Methods To gain a synoptic view of therapeutic targets for HD, we have carried out a variety of bioinformatical and statistical analyses to scrutinize the functional association of genes curated in the HD Research Crossroads database. In particular, enrichment analyses were performed with respect to Gene Ontology categories, KEGG signaling pathways, and Pfam protein families. For selected processes, we also analyzed differential expression, using published microarray data. Additionally, we generated a candidate set of novel genetic modifiers of HD by combining information from the HD Research Crossroads database with previous genome-wide linkage studies. Results Our analyses led to a comprehensive identification of molecular mechanisms associated with HD. Remarkably, we not only recovered processes and pathways, which have frequently been linked to HD (such as cytotoxicity, apoptosis, and calcium signaling, but also found strong indications for other potentially disease-relevant mechanisms that have been less intensively studied in the context of HD (such as the cell cycle and RNA splicing, as well as Wnt and ErbB signaling. For follow-up studies, we provide a regularly updated compendium of molecular mechanism, that are

  9. Linking CALL and SLA: Using the IRIS Database to Locate Research Instruments

    Science.gov (United States)

    Handley, Zöe; Marsden, Emma

    2014-01-01

    To establish an evidence base for future computer-assisted language learning (CALL) design, CALL research needs to move away from CALL versus non-CALL comparisons, and focus on investigating the differential impact of individual coding elements, that is, specific features of a technology which might have an impact on learning (Pederson, 1987).…

  10. The Development of a Video Database for Language Educational Research Projects

    Science.gov (United States)

    Hawkey, Roger; Thompson, Sue; Turner, Richard

    2007-01-01

    The analysis of classroom observation data is seen as increasingly important in research on the impact of high-stakes language tests or new foreign-language programmes on students, teachers and other stakeholders. Video-recordings of language teaching and learning in classrooms impacted by such tests or programmes can provide revealing data,…

  11. National databases and rheumatology research II: the National Health and Nutrition Examination Surveys.

    Science.gov (United States)

    Sokka, Tuulikki; Krishnan, Eswar

    2004-11-01

    Three National Health and Nutrition Examination Surveys were conducted in the United States between 1971 and 1994 to provide data on the nutritional and health status of the population and on specific target conditions. This article describes features of the surveys and provides examples of research on musculoskeletal disorders that used the survey data.

  12. Integrating NASA's Land Analysis System (LAS) image processing software with an appropriate Geographic Information System (GIS): A review of candidates in the public domain

    Science.gov (United States)

    Rochon, Gilbert L.

    1989-01-01

    A user requirements analysis (URA) was undertaken to determine and appropriate public domain Geographic Information System (GIS) software package for potential integration with NASA's LAS (Land Analysis System) 5.0 image processing system. The necessity for a public domain system was underscored due to the perceived need for source code access and flexibility in tailoring the GIS system to the needs of a heterogenous group of end-users, and to specific constraints imposed by LAS and its user interface, Transportable Applications Executive (TAE). Subsequently, a review was conducted of a variety of public domain GIS candidates, including GRASS 3.0, MOSS, IEMIS, and two university-based packages, IDRISI and KBGIS. The review method was a modified version of the GIS evaluation process, development by the Federal Interagency Coordinating Committee on Digital Cartography. One IEMIS-derivative product, the ALBE (AirLand Battlefield Environment) GIS, emerged as the most promising candidate for integration with LAS. IEMIS (Integrated Emergency Management Information System) was developed by the Federal Emergency Management Agency (FEMA). ALBE GIS is currently under development at the Pacific Northwest Laboratory under contract with the U.S. Army Corps of Engineers' Engineering Topographic Laboratory (ETL). Accordingly, recommendations are offered with respect to a potential LAS/ALBE GIS linkage and with respect to further system enhancements, including coordination with the development of the Spatial Analysis and Modeling System (SAMS) GIS in Goddard's IDM (Intelligent Data Management) developments in Goddard's National Space Science Data Center.

  13. 语义数据库Freebase研究%Research on Semantic Database Freebase

    Institute of Scientific and Technical Information of China (English)

    李俊

    2011-01-01

    Based on literature research and case studies, this paper makes an analysis on Freebase. It introduces the differences between Freebase and other semantic projects, studies the sources of Freebase, analyses its structure and features, and mainly focuses on the research of its knowledge representation and organization. This paper also explores the applications based on Freebase and the advices on how to use Freebase, which provides a thought to the research on advanced information technology as well.%采用文献研究与案例分析方法,对语义数据库Freebase进行研究。介绍Freebase与其他语义Web项目的区别及其数据来源,并分析其数据库架构的技术特性,对其在语义Web环境下知识表示和组织的理念与技术进行重点研究。同时对国外基于Freebase的应用进行探讨,为国内图书馆使用Freebase数据提供建议。

  14. Heart research advances using database search engines, Human Protein Atlas and the Sydney Heart Bank.

    Science.gov (United States)

    Li, Amy; Estigoy, Colleen; Raftery, Mark; Cameron, Darryl; Odeberg, Jacob; Pontén, Fredrik; Lal, Sean; Dos Remedios, Cristobal G

    2013-10-01

    This Methodological Review is intended as a guide for research students who may have just discovered a human "novel" cardiac protein, but it may also help hard-pressed reviewers of journal submissions on a "novel" protein reported in an animal model of human heart failure. Whether you are an expert or not, you may know little or nothing about this particular protein of interest. In this review we provide a strategic guide on how to proceed. We ask: How do you discover what has been published (even in an abstract or research report) about this protein? Everyone knows how to undertake literature searches using PubMed and Medline but these are usually encyclopaedic, often producing long lists of papers, most of which are either irrelevant or only vaguely relevant to your query. Relatively few will be aware of more advanced search engines such as Google Scholar and even fewer will know about Quertle. Next, we provide a strategy for discovering if your "novel" protein is expressed in the normal, healthy human heart, and if it is, we show you how to investigate its subcellular location. This can usually be achieved by visiting the website "Human Protein Atlas" without doing a single experiment. Finally, we provide a pathway to discovering if your protein of interest changes its expression level with heart failure/disease or with ageing. Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.

  15. Reliability Of A Surgeon-Reported Morbidity And Mortality Database: A Comparison Of Short-Term Morbidity Between The Scoliosis Research Society And National Surgical Quality Improvement Program Databases

    Science.gov (United States)

    Martin, Christopher T.; Pugely, Andrew J.; Gao, Yubo; Skovrlj, Branko; Lee, Nathan J.; Cho, Samuel K.; Mendoza-Lattes, Sergio

    2016-01-01

    Background There exists a lack of comparison between large national healthcare databases reporting surgical morbidity and mortality. Prior authors have expressed concern that the Scoliosis Research Society (SRS) membership may have underreported complications in spinal surgery. Thus, the purpose of the present study was to compare the incidence of morbidity between the SRS and National Surgical Quality Improvement Program (NSQIP) databases. Methods We reviewed patients enrolled between 2012 and 2013, with a total of 96,875 patients identified in the SRS dataset and 15,909 in the combined adult and pediatric NSQIP dataset. Patients were matched based on diagnostic category,and a univariate analysis was used to compare reported complication rates in the categories of perioperative infection, neurologic injury, and mortality. The SRS database only requires detailed demographic data reporting on patients that have had a complication event. We compared the demographics and comorbidities of this subgroup, and used this as a surrogate to assess the potential magnitude of confounders. Results Small differences existed between the SRS and NSQIP databases in terms of mortality (0.1% v. 0.2%), infection (1.2% v. 2%), and neurologic injury (0.8% v. 0.1%) (p<0.001 for each comparison). Infection rates were consistently lower across multiple diagnostic sub-categories in the SRS database, whereas neurologic injury rates were consistently lower in the NSQIP database. These differences reached statistical significance across several diagnostic subcategories, but the clinical magnitude of the differences was small. Amongst the patients with a complication, modest differences in comorbidities existed between the two cohorts. Conclusion Overall, the incidence of short-term morbidity and mortality was similar between the two databases. There were modest differences in comorbidities, which may explain the small differences observed in morbidity. Concerns regarding possible under

  16. Veterans Administration Databases

    Science.gov (United States)

    The Veterans Administration Information Resource Center provides database and informatics experts, customer service, expert advice, information products, and web technology to VA researchers and others.

  17. Scopus database: a review.

    Science.gov (United States)

    Burnham, Judy F

    2006-03-08

    The Scopus database provides access to STM journal articles and the references included in those articles, allowing the searcher to search both forward and backward in time. The database can be used for collection development as well as for research. This review provides information on the key points of the database and compares it to Web of Science. Neither database is inclusive, but complements each other. If a library can only afford one, choice must be based in institutional needs.

  18. Pediatric critical care physician-administered procedural sedation using propofol: a report from the Pediatric Sedation Research Consortium Database.

    Science.gov (United States)

    Kamat, Pradip P; McCracken, Courtney E; Gillespie, Scott E; Fortenberry, James D; Stockwell, Jana A; Cravero, Joseph P; Hebbar, Kiran B

    2015-01-01

    Increasing demand for pediatric procedural sedation has resulted in a marked increase in provision of pediatric procedural sedation by pediatric critical care physicians both inside and outside of the ICU. Reported experience of pediatric critical care physicians-administered pediatric procedural sedation is limited. We used the Pediatric Sedation Research Consortium database to evaluate a multicenter experience with propofol by pediatric critical care physicians in all settings. Review of national Pediatric Sedation Research Consortium database to identify pediatric procedural sedation provided by pediatric critical care physicians from 2007 to 2012. Demographic and clinical data were collected to describe pediatric procedural sedation selection, location, and delivery. Multivariable logistic regression analysis was performed to identify risk factors associated with pediatric procedural sedation-related adverse events and complications. A total of 91,189 pediatric procedural sedation performed by pediatric critical care physicians using propofol were included in the database. Median age was 60.0 months (range, 0-264 months; interquartile range, 34.0-132.0); 81.9% of patients were American Society of Anesthesiologists class I or II. Most sedations were performed in dedicated sedation or radiology units (80.9%). Procedures were successfully completed in 99.9% of patients. A propofol bolus alone was used in 52.8%, and 41.7% received bolus plus continuous infusion. Commonly used adjunctive medications were lidocaine (35.3%), opioids (23.3%), and benzodiazepines (16.4%). Overall adverse event incidence was 5.0% (95% CI, 4.9-5.2%), which included airway obstruction (1.6%), desaturation (1.5%), coughing (1.0%), and emergent airway intervention (0.7%). No deaths occurred; a single cardiac arrest was reported in a 13-month-old child receiving propofol and ketamine, with no untoward neurologic sequelae. Risk factors associated with adverse event included: location of

  19. An integrated, ontology-driven approach to constructing observational databases for research.

    Science.gov (United States)

    Hsu, William; Gonzalez, Nestor R; Chien, Aichi; Pablo Villablanca, J; Pajukanta, Päivi; Viñuela, Fernando; Bui, Alex A T

    2015-06-01

    The electronic health record (EHR) contains a diverse set of clinical observations that are captured as part of routine care, but the incomplete, inconsistent, and sometimes incorrect nature of clinical data poses significant impediments for its secondary use in retrospective studies or comparative effectiveness research. In this work, we describe an ontology-driven approach for extracting and analyzing data from the patient record in a longitudinal and continuous manner. We demonstrate how the ontology helps enforce consistent data representation, integrates phenotypes generated through analyses of available clinical data sources, and facilitates subsequent studies to identify clinical predictors for an outcome of interest. Development and evaluation of our approach are described in the context of studying factors that influence intracranial aneurysm (ICA) growth and rupture. We report our experiences in capturing information on 78 individuals with a total of 120 aneurysms. Two example applications related to assessing the relationship between aneurysm size, growth, gene expression modules, and rupture are described. Our work highlights the challenges with respect to data quality, workflow, and analysis of data and its implications toward a learning health system paradigm.

  20. An open-database of Grape Harvest dates for climate research: data description and quality assessment

    Directory of Open Access Journals (Sweden)

    V. Daux

    2011-11-01

    not homogenous. Extremely late years all occur during a two-century long time-window from the early 17th to the early 19th century, while extremely early years are frequent during the 16th and since the mid-19th century.

    The dataset is made accessible for climate research through the Internet. It should allow a variety of climate studies, including reconstructions of atmospheric circulation over Western Europe.

  1. Acupuncture in stroke rehabilitation Literature retrieval based on international databases

    Institute of Scientific and Technical Information of China (English)

    Feng Sun; Jinchun Wang; Xia Wen

    2012-01-01

    OBJECTIVE: To identify global research trends of acupuncture in stroke rehabilitation using a bibliometric analysis of the Web of Science and the Clinical Trials registry database (ClinicalTrials.gov). DATA RETRIEVAL: We performed a bibliometric analysis of data retrievals for acupuncture in stroke rehabilitation from 1992 to 2011 using the Web of Science and ClinicalTrials.gov. SELECTION CRITERIA: Inclusion criteria: (1) Web of Science: (a) Peer-reviewed articles on acupuncture in stroke rehabilitation that were published and indexed in the Web of Science. (b) Type of articles: original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material and news items. (c) Year of publication: 1992-2011. (2) ClinicalTrials.gov: All clinical trials relating to acupuncture in stroke rehabilitation were searched in this database. Exclusion criteria: (1) Web of Science: (a) Articles that required manual searching or telephone access. (b) We excluded documents that were not published in the public domain. (c) We excluded a number of corrected papers from the total number of articles. (2) ClinicalTrials.gov: (a) We excluded clinical trials that were not in the ClinicalTrials.gov database. (b) We excluded clinical trials that dealt with magnetic stimulation other than acupuncture in stroke rehabilitation in the ClinicalTrials.gov database. MAIN OUTCOME MEASURES: (1) Type of literature; (2) annual publication output; (3) distribution according to journals; (4) distribution according to country; (5) distribution according to institution; (6) top cited articles over the last 20 years; and (7) clinical trials registered.RESULTS: (1) In all, 92 studies on acupuncture in stroke rehabilitation appeared in the Web of Science from 1992 to 2011, almost half of which derived from Chinese and American authors and institutes. The number of studies addressing acupuncture in stroke rehabilitation has gradually increased over the past 20 years. Most

  2. Cloud-Based NoSQL Open Database of Pulmonary Nodules for Computer-Aided Lung Cancer Diagnosis and Reproducible Research.

    Science.gov (United States)

    Ferreira Junior, José Raniery; Oliveira, Marcelo Costa; de Azevedo-Marques, Paulo Mazzoncini

    2016-12-01

    Lung cancer is the leading cause of cancer-related deaths in the world, and its main manifestation is pulmonary nodules. Detection and classification of pulmonary nodules are challenging tasks that must be done by qualified specialists, but image interpretation errors make those tasks difficult. In order to aid radiologists on those hard tasks, it is important to integrate the computer-based tools with the lesion detection, pathology diagnosis, and image interpretation processes. However, computer-aided diagnosis research faces the problem of not having enough shared medical reference data for the development, testing, and evaluation of computational methods for diagnosis. In order to minimize this problem, this paper presents a public nonrelational document-oriented cloud-based database of pulmonary nodules characterized by 3D texture attributes, identified by experienced radiologists and classified in nine different subjective characteristics by the same specialists. Our goal with the development of this database is to improve computer-aided lung cancer diagnosis and pulmonary nodule detection and classification research through the deployment of this database in a cloud Database as a Service framework. Pulmonary nodule data was provided by the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI), image descriptors were acquired by a volumetric texture analysis, and database schema was developed using a document-oriented Not only Structured Query Language (NoSQL) approach. The proposed database is now with 379 exams, 838 nodules, and 8237 images, 4029 of them are CT scans and 4208 manually segmented nodules, and it is allocated in a MongoDB instance on a cloud infrastructure.

  3. CERN - Researching the building blocks of matter

    CERN Multimedia

    2008-01-01

    At the heart of understanding the Universe and life itself, the exploration carried out by CERN is at the pinnacle of modern research and currently in the eye of the public domain more than ever before. (1 page)

  4. Rat Genome Database (RGD)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Rat Genome Database (RGD) is a collaborative effort between leading research institutions involved in rat genetic and genomic research to collect, consolidate,...

  5. Synthesis of Available Research and Databases on the Migrant Education Program. Volume I: Federal, State, and Local Data.

    Science.gov (United States)

    Gutmann, Babette; And Others

    This report examines federal, state, and local databases containing information on migrant workers and their children, identifies their common characteristics, and assesses their potential utility to inform educational policy analysis. General criteria used to evaluate each database's strengths and weaknesses include standardization, reliability,…

  6. Preliminary results of the Social Impact Research Group of MEDEX: the request database (2000–2002 of two Meteorological Services

    Directory of Open Access Journals (Sweden)

    J. Amaro

    2010-12-01

    Full Text Available One of the aims of the MEDEX project is to improve the knowledge of high-impact weather events in the Mediterranean. According to the guidelines of this project, a pilot study was carried out in two regions of Spain (the Balearic Islands and Catalonia by the Social Impact Research group of MEDEX. The main goal is to suggest some general and suitable criteria about how to analyse requests received in Meteorological Services arising out of the damage caused by weather events. Thus, all the requests received between 2000 and 2002 at the Servei Meteorològic de Catalunya as well as at the Division of AEMET in the Balearic Islands were analysed.

    Firstly, the proposed criteria in order to build the database are defined and discussed. Secondly, the temporal distribution of the requests for damage claims is analysed. On average, almost half of them were received during the first month after the event happened. During the first six months, the percentage increases by 90%. Thirdly, various factors are taken into account to determine the impact of specific events on society. It is remarkable that the greatest number of requests is for those episodes with simultaneous heavy rain and strong wind, and finally, those that are linked to high population density.

  7. ZIKV - CDB: A Collaborative Database to Guide Research Linking SncRNAs and ZIKA Virus Disease Symptoms.

    Directory of Open Access Journals (Sweden)

    Victor Satler Pylro

    2016-06-01

    Full Text Available In early 2015, a ZIKA Virus (ZIKV infection outbreak was recognized in northeast Brazil, where concerns over its possible links with infant microcephaly have been discussed. Providing a causal link between ZIKV infection and birth defects is still a challenge. MicroRNAs (miRNAs are small noncoding RNAs (sncRNAs that regulate post-transcriptional gene expression by translational repression, and play important roles in viral pathogenesis and brain development. The potential for flavivirus-mediated miRNA signalling dysfunction in brain-tissue development provides a compelling hypothesis to test the perceived link between ZIKV and microcephaly.Here, we applied in silico analyses to provide novel insights to understand how Congenital ZIKA Syndrome symptoms may be related to an imbalance in miRNAs function. Moreover, following World Health Organization (WHO recommendations, we have assembled a database to help target investigations of the possible relationship between ZIKV symptoms and miRNA-mediated human gene expression.We have computationally predicted both miRNAs encoded by ZIKV able to target genes in the human genome and cellular (human miRNAs capable of interacting with ZIKV genomes. Our results represent a step forward in the ZIKV studies, providing new insights to support research in this field and identify potential targets for therapy.

  8. Contextualising the role of the gatekeeper in social science research

    African Journals Online (AJOL)

    public domain, permission needs to be obtained from the legitimate authorities in ... The role and influence of gatekeepers in social science research has been .... Conversely, denial of access, by virtue of the researcher's relationship with the.

  9. Database Publication Practices

    DEFF Research Database (Denmark)

    Bernstein, P.A.; DeWitt, D.; Heuer, A.

    2005-01-01

    There has been a growing interest in improving the publication processes for database research papers. This panel reports on recent changes in those processes and presents an initial cut at historical data for the VLDB Journal and ACM Transactions on Database Systems.......There has been a growing interest in improving the publication processes for database research papers. This panel reports on recent changes in those processes and presents an initial cut at historical data for the VLDB Journal and ACM Transactions on Database Systems....

  10. Relational databases

    CERN Document Server

    Bell, D A

    1986-01-01

    Relational Databases explores the major advances in relational databases and provides a balanced analysis of the state of the art in relational databases. Topics covered include capture and analysis of data placement requirements; distributed relational database systems; data dependency manipulation in database schemata; and relational database support for computer graphics and computer aided design. This book is divided into three sections and begins with an overview of the theory and practice of distributed systems, using the example of INGRES from Relational Technology as illustration. The

  11. Exploiting the potential of large databases of electronic health records for research using rapid search algorithms and an intuitive query interface.

    Science.gov (United States)

    Tate, A Rosemary; Beloff, Natalia; Al-Radwan, Balques; Wickson, Joss; Puri, Shivani; Williams, Timothy; Van Staa, Tjeerd; Bleach, Adrian

    2014-01-01

    UK primary care databases, which contain diagnostic, demographic and prescribing information for millions of patients geographically representative of the UK, represent a significant resource for health services and clinical research. They can be used to identify patients with a specified disease or condition (phenotyping) and to investigate patterns of diagnosis and symptoms. Currently, extracting such information manually is time-consuming and requires considerable expertise. In order to exploit more fully the potential of these large and complex databases, our interdisciplinary team developed generic methods allowing access to different types of user. Using the Clinical Practice Research Datalink database, we have developed an online user-focused system (TrialViz), which enables users interactively to select suitable medical general practices based on two criteria: suitability of the patient base for the intended study (phenotyping) and measures of data quality. An end-to-end system, underpinned by an innovative search algorithm, allows the user to extract information in near real-time via an intuitive query interface and to explore this information using interactive visualization tools. A usability evaluation of this system produced positive results. We present the challenges and results in the development of TrialViz and our plans for its extension for wider applications of clinical research. Our fast search algorithms and simple query algorithms represent a significant advance for users of clinical research databases.

  12. Prototype of an Integrated Hurricane Information System for Research: Design and Implementation of the Database and Web Portal

    Science.gov (United States)

    Li, P. P.; Knosp, B.; Vu, Q. A.; Hristova-Veleva, S.; Chao, Y.; Vane, D.; Lambrigtsen, B.; Su, H.; Dang, V.; Fovell, R.; Willis, J.; Tanelli, S.; Fishbein, E.; Ao, C. O.; Poulsen, W. L.; Park, K. J.; Fetzer, E.; Vazquez, J.; Callahan, P. S.; Marcus, S.; Garay, M.; Kahn, R.; Haddad, Z.

    2007-12-01

    location placemark to see the time, location, and the intensity of the hurricane. Large scale datasets, such as SST or aerosol optical depth can be overlaid on top of the hurricane track in Google Map. In addition, available satellite and in-situ data during the hurricane period are displayed as little bars in a time line organized by datasets. When clicking a little bar, pre-generated plots for the selected dataset will be displayed in a separate window together with all other datasets co-located around the same time. The raw data in user-specified format can be downloaded for further analysis or model integration. As for the 3D model data, Live Access Server (LAS) is used to provide custom subsets and on-the-fly visualization. The site is dynamically configured using a backend relational database that is designed to let users easily browse through the website to find data and plots that are pertinent to their research. In this presentation, we will describe the current status of the integrated hurricane information system prototype, the design and the implementation of the hurricane database and portal, and future enhancements.

  13. Reducing the probability of false positive research findings by pre-publication validation – Experience with a large multiple sclerosis database

    Directory of Open Access Journals (Sweden)

    Heinz Moritz

    2008-04-01

    Full Text Available Abstract Background Published false positive research findings are a major problem in the process of scientific discovery. There is a high rate of lack of replication of results in clinical research in general, multiple sclerosis research being no exception. Our aim was to develop and implement a policy that reduces the probability of publishing false positive research findings. We have assessed the utility to work with a pre-publication validation policy after several years of research in the context of a large multiple sclerosis database. Methods The large database of the Sylvia Lawry Centre for Multiple Sclerosis Research was split in two parts: one for hypothesis generation and a validation part for confirmation of selected results. We present case studies from 5 finalized projects that have used the validation policy and results from a simulation study. Results In one project, the "relapse and disability" project as described in section II (example 3, findings could not be confirmed in the validation part of the database. The simulation study showed that the percentage of false positive findings can exceed 20% depending on variable selection. Conclusion We conclude that the validation policy has prevented the publication of at least one research finding that could not be validated in an independent data set (and probably would have been a "true" false-positive finding over the past three years, and has led to improved data analysis, statistical programming, and selection of hypotheses. The advantages outweigh the lost statistical power inherent in the process.

  14. Conditioning Probabilistic Databases

    CERN Document Server

    Koch, Christoph

    2008-01-01

    Past research on probabilistic databases has studied the problem of answering queries on a static database. Application scenarios of probabilistic databases however often involve the conditioning of a database using additional information in the form of new evidence. The conditioning problem is thus to transform a probabilistic database of priors into a posterior probabilistic database which is materialized for subsequent query processing or further refinement. It turns out that the conditioning problem is closely related to the problem of computing exact tuple confidence values. It is known that exact confidence computation is an NP-hard problem. This has lead researchers to consider approximation techniques for confidence computation. However, neither conditioning nor exact confidence computation can be solved using such techniques. In this paper we present efficient techniques for both problems. We study several problem decomposition methods and heuristics that are based on the most successful search techn...

  15. Biofuel Database

    Science.gov (United States)

    Biofuel Database (Web, free access)   This database brings together structural, biological, and thermodynamic data for enzymes that are either in current use or are being considered for use in the production of biofuels.

  16. Onzekere databases

    NARCIS (Netherlands)

    van Keulen, Maurice

    Een recente ontwikkeling in het databaseonderzoek betret zogenaamde 'onzekere databases'. Dit artikel beschrijft wat onzekere databases zijn, hoe ze gebruikt kunnen worden en welke toepassingen met name voordeel zouden kunnen hebben van deze technologie.

  17. Community Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This excel spreadsheet is the result of merging at the port level of several of the in-house fisheries databases in combination with other demographic databases such...

  18. Specialist Bibliographic Databases

    OpenAIRE

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Voronov, Alexander A.; Trukhachev, Vladimir I.; Kostyukova, Elena I.; Gerasimov, Alexey N.; Kitas, George D.

    2016-01-01

    Specialist bibliographic databases offer essential online tools for researchers and authors who work on specific subjects and perform comprehensive and systematic syntheses of evidence. This article presents examples of the established specialist databases, which may be of interest to those engaged in multidisciplinary science communication. Access to most specialist databases is through subscription schemes and membership in professional associations. Several aggregators of information and d...

  19. Research of Qingdao Fundamental Geographic Database Construction%青岛市基础地理空间数据库建设研究

    Institute of Scientific and Technical Information of China (English)

    赵云华; 刘加生; 乔新

    2013-01-01

    The paper analyzes the status of the fundamental geographic information resources of Qingdao and researches the the spatial database technology.An optimized way of constructing fundamental geographic database of Qingdao is found out.%通过对基础地理数据的分析、空间数据库技术的认识、结合青岛基础地理信息资源的现状,研究出建立青岛市基础地理空间数据库的最优方法.

  20. Database Administrator

    Science.gov (United States)

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  1. Database Administrator

    Science.gov (United States)

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  2. Iranian Nephrology and Urology Research Output in the Past Two Decades: A Bibliographic Analysis of Medline Database

    Directory of Open Access Journals (Sweden)

    Einollahi

    2015-09-01

    Full Text Available Context We performed a bibliometric search to evaluate the number of papers published in the field of nephrology and urology by Iranian researchers in the past two decades. Evidence Acquisition We did an online search in abstract/title part of articles with 129 keywords such as kidney, renal, hemodialysis, transplant, nephrology, glomerulonephritis, ureteral, nephrolithiasis, and etc. Endnote software version 7 was used to search articles published in PubMed database from November 1993 to November 2013. Those articles in which Iran was the affiliation of at least one of the authors were selected. These articles in the field of nephrology and urology were analyzed regarding the name of originated institution, field of study, total number of publications, type of study, collaboration rate of Iranian nephrologist and urologists for every year, annual sharing of Iranian articles in five journals with highest impact factor (IF and journal IF. Results The total number of publications in the field of nephrology and urology was 3,771 (average of 189 papers per year. Most of the Iranian nephrology and urology papers were from the capital city, Tehran (50.03%. There was an increasing trend in the number of publications over the years. Most papers were about transplantation (44.6%, nephrology (20.9% and hemodialysis (16.4%. Of all, 53.7% were retrospective articles, whereas the proportion of clinical trials was relatively small (10.8%. Conclusions Although Iranian publications in the field of nephrology and urology have had a considerable and significant increase in the recent years amongst the Middle Eastern countries, there is a wide distance to be a science exporter country.

  3. Database security of financial software and audit techniques research%财务软件数据库安全与审计技术研究

    Institute of Scientific and Technical Information of China (English)

    张晓宁; 孙泽明; 董冰; 陈敬萱

    2016-01-01

    本文以财务软件数据库安全与审计追踪技术为主线,通过数据库存储以及调用过程中的数据库加密来达到数据库的安全性要求。通过审计追踪技术,来解决人工审计相对繁琐而且效率不高,容易造成安全隐患,难以追查造成事故原因等问题。本系统使用Delphi7.0作为主要软件开发工具,并利用SQL Server 2000进行数据库开发与研究,最终实现对财务预结算软件的应用,并完成数据库的加密算法和审计追踪的设计,有效地提高了数据库的安全性和审计的高效性。文章还对加密后的数据库进行了仿真验证,结果表明,数据库可以通过加密来防止攻击破解,具有较高的实用价值。%Taking the Financial software database security design and audit tracking technology command as the main clue, through the database to store and call process, database security requirements is achieved by using database encryption . Through audit tracking, artificial audit to resolve relatively cumbersome and inefficient, likely to cause safety problems, it is difficult to trace the origin of the accident caused by other problems. The system uses Delphi7.0 as the software for developing, and uses SQL Server 2000 to develop and research database. The research ultimately achieves financial accounting settlement application for forcing, and completes the database encryption algorithm, therefore effectively improve the security of the database. The article especially discusses the system’ s database of the simulation design. The simulation results show that database can be encrypted to prevent from attacking, which has high practical value.

  4. A lake-centric geospatial database to guide research and inform management decisions in an Arctic watershed in northern Alaska experiencing climate and land-use changes

    Science.gov (United States)

    Jones, Benjamin M.; Arp, Christopher D.; Whitman, Matthew S.; Nigro, Debora A.; Nitze, Ingmar; Beaver, John; Gadeke, Anne; Zuck, Callie; Liljedahl, Anna K.; Daanen, Ronald; Torvinen, Eric; Fritz, Stacey; Grosse, Guido

    2017-01-01

    Lakes are dominant and diverse landscape features in the Arctic, but conventional land cover classification schemes typically map them as a single uniform class. Here, we present a detailed lake-centric geospatial database for an Arctic watershed in northern Alaska. We developed a GIS dataset consisting of 4362 lakes that provides information on lake morphometry, hydrologic connectivity, surface area dynamics, surrounding terrestrial ecotypes, and other important conditions describing Arctic lakes. Analyzing the geospatial database relative to fish and bird survey data shows relations to lake depth and hydrologic connectivity, which are being used to guide research and aid in the management of aquatic resources in the National Petroleum Reserve in Alaska. Further development of similar geospatial databases is needed to better understand and plan for the impacts of ongoing climate and land-use changes occurring across lake-rich landscapes in the Arctic.

  5. Database Description - KOME | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available [ Credits ] BLAST Search Image Search Home About Archive Update History Contact us KOME Database... Description General information of database Database name Knowledge-based Oryza Molecular biol...baraki 305-8602, Japan National Institute of Agrobiological Sciences Plant Genome Research Unit Shoshi Kikuchi E-mail : Database... classification Plant databases - Rice Organism Taxonomy Name: Oryza sativa Taxonomy ID: 4530 Database...A clones that were completely sequenced in the Rice full-length cDNA project is shown in the database. The f

  6. The Danish Anaesthesia Database

    DEFF Research Database (Denmark)

    Antonsen, Kristian; Rosenstock, Charlotte Vallentin; Lundstrøm, Lars Hyldborg

    2016-01-01

    AIM OF DATABASE: The aim of the Danish Anaesthesia Database (DAD) is the nationwide collection of data on all patients undergoing anesthesia. Collected data are used for quality assurance, quality development, and serve as a basis for research projects. STUDY POPULATION: The DAD was founded in 2004...

  7. World Database of Happiness

    NARCIS (Netherlands)

    R. Veenhoven (Ruut)

    1995-01-01

    textabstractABSTRACT The World Database of Happiness is an ongoing register of research on subjective appreciation of life. Its purpose is to make the wealth of scattered findings accessible, and to create a basis for further meta-analytic studies. The database involves four sections:
    1.

  8. Database Publication Practices

    DEFF Research Database (Denmark)

    Bernstein, P.A.; DeWitt, D.; Heuer, A.

    2005-01-01

    There has been a growing interest in improving the publication processes for database research papers. This panel reports on recent changes in those processes and presents an initial cut at historical data for the VLDB Journal and ACM Transactions on Database Systems....

  9. An organic database system

    NARCIS (Netherlands)

    M.L. Kersten (Martin); A.P.J.M. Siebes (Arno)

    1999-01-01

    textabstractThe pervasive penetration of database technology may suggest that we have reached the end of the database research era. The contrary is true. Emerging technology, in hardware, software, and connectivity, brings a wealth of opportunities to push technology to a new level of maturity.

  10. World Database of Happiness

    NARCIS (Netherlands)

    R. Veenhoven (Ruut)

    1995-01-01

    textabstractABSTRACT The World Database of Happiness is an ongoing register of research on subjective appreciation of life. Its purpose is to make the wealth of scattered findings accessible, and to create a basis for further meta-analytic studies. The database involves four sections:
    1. Bib

  11. World Database of Happiness

    NARCIS (Netherlands)

    R. Veenhoven (Ruut)

    1995-01-01

    textabstractABSTRACT The World Database of Happiness is an ongoing register of research on subjective appreciation of life. Its purpose is to make the wealth of scattered findings accessible, and to create a basis for further meta-analytic studies. The database involves four sections:
    1. Bib

  12. Reflections on a decade of research by ASEAN dental faculties: analysis of publications from ISI-WOS databases from 2000 to 2009.

    Science.gov (United States)

    Sirisinha, Stitaya; Koontongkaew, Sittichai; Phantumvanit, Prathip; Wittayawuttikul, Ruchareka

    2011-05-01

    This communication analyzed research publications in dentistry in the Institute of Scientific Information Web of Science databases of 10 dental faculties in the Association of South-East Asian Nations (ASEAN) from 2000 to 2009. The term used for the "all-document types" search was "Faculty of Dentistry/College of Dentistry." Abstracts presented at regional meetings were also included in the analysis. The Times Higher Education System QS World University Rankings showed that universities in the region fare poorly in world university rankings. Only the National University of Singapore and Nanyang Technological University appeared in the top 100 in 2009; 19 universities in the region, including Indonesia, Malaysia, the Philippines, Singapore, and Thailand, appeared in the top 500. Data from the databases showed that research publications by dental institutes in the region fall short of their Asian counterparts. Singapore and Thailand are the most active in dental research of the ASEAN countries.

  13. Further Research is Required to Determine Which Database Products Best Support Research in Public Administration. A review of: Tucker, James, Corey. “Database Support for Research in Public Administration.” Behavioral & Social Sciences Librarian 24.1 (2005: 47-60.

    Directory of Open Access Journals (Sweden)

    David Hook

    2006-06-01

    Full Text Available Objective – To examine the extent to which six commercial database products support student and faculty research in the area of public administration. Design – Bibliometric study. Setting – Academic library in the United States. Subjects – Six commercial business‐related database products were examined: Proquest’s ABI/INFORM Global edition (ABI, EBSCO’s Business Source Premier (BSP, Gale’s General BusinessFile ASAP (GBF, EBSCO’s Academic Search Premier (ASP, EBSCO’s Expanded Academic Index (EAI and Proquest’s International Academic Research Library (ARL. Three of the databases (ABI, BSP, GBF were chosen because they address the management, human resource, and financing elements of public administration. The other three (ASP, EAI, ARL were included because of their multidisciplinary coverage. Methods – A list of journal titles covering public administration was assembled from the Institute of Scientific Information’s Social Sciences Citation Index and previously published lists of recommended journals in the field. The author then compared the compiled list of journal titles against the journal titles indexed by the six database products. He further analyzed the results by level of journal coverage (abstract only, full‐text, and full‐text with embargo and subject area based on categories described in Ulrich’s Periodicals Directory. Main Results – The study found that three of the six database products ‐‐EAI, BSP, and ARL ‐‐ provide indexing for the greatest number of public administration journals contained in the compiled list. EIA and ARL cover the greatest number of those that are full‐text journals, while BSP and ASP cover the greatest number of those full‐text journals limited by publisher embargoes. Conclusion – The author concludes that of the six databases examined, EAI, BSP, and ARL are the best for public administration research, based on their strength in the subject areas of public

  14. The Danish Melanoma Database

    DEFF Research Database (Denmark)

    Hölmich, Lisbet Rosenkrantz; Klausen, Siri; Spaun, Eva

    2016-01-01

    AIM OF DATABASE: The aim of the database is to monitor and improve the treatment and survival of melanoma patients. STUDY POPULATION: All Danish patients with cutaneous melanoma and in situ melanomas must be registered in the Danish Melanoma Database (DMD). In 2014, 2,525 patients with invasive......, nature, and treatment hereof is registered. In case of death, the cause and date are included. Currently, all data are entered manually; however, data catchment from the existing registries is planned to be included shortly. DESCRIPTIVE DATA: The DMD is an old research database, but new as a clinical...

  15. GestuRe and ACtion Exemplar (GRACE) video database: stimuli for research on manners of human locomotion and iconic gestures.

    Science.gov (United States)

    Aussems, Suzanne; Kwok, Natasha; Kita, Sotaro

    2017-09-15

    Human locomotion is a fundamental class of events, and manners of locomotion (e.g., how the limbs are used to achieve a change of location) are commonly encoded in language and gesture. To our knowledge, there is no openly accessible database containing normed human locomotion stimuli. Therefore, we introduce the GestuRe and ACtion Exemplar (GRACE) video database, which contains 676 videos of actors performing novel manners of human locomotion (i.e., moving from one location to another in an unusual manner) and videos of a female actor producing iconic gestures that represent these actions. The usefulness of the database was demonstrated across four norming experiments. First, our database contains clear matches and mismatches between iconic gesture videos and action videos. Second, the male actors and female actors whose action videos matched the gestures in the best possible way, perform the same actions in very similar manners and different actions in highly distinct manners. Third, all the actions in the database are distinct from each other. Fourth, adult native English speakers were unable to describe the 26 different actions concisely, indicating that the actions are unusual. This normed stimuli set is useful for experimental psychologists working in the language, gesture, visual perception, categorization, memory, and other related domains.

  16. 基于数据库安全的研究与应用%Research and Application of Database Security

    Institute of Scientific and Technical Information of China (English)

    葛耀武; 张明玉; 方芳

    2014-01-01

    With the rapid development of computer technology and communication technology, big data era has arrived. To follow the era demand, the database technology provides the solution. The database as the aggregates of information, it shoulders the task of storing and managing data, and its security is also becoming increasingly important. This article discusses the definition of database and the security threat faced by database system, and discusses the database-related security technology.%伴随着计算机技术以及通信技术的快速发展,大数据时代已经来临。而数据库技术为顺应这一时代要求提供了方案,数据库作为信息的聚集体,担负着存储和管理数据信息的任务,其安全性也越来越重要。本文论述了数据库安全定义、数据库系统面临的安全威胁,探讨了数据库相关的安全技术。

  17. The Molecular Biology Database Collection: 2008 update.

    Science.gov (United States)

    Galperin, Michael Y

    2008-01-01

    The Nucleic Acids Research online Molecular Biology Database Collection is a public repository that lists more than 1000 databases described in this and previous Nucleic Acids Research annual database issues, as well as a selection of molecular biology databases described in other journals. All databases included in this Collection are freely available to the public. The 2008 update includes 1078 databases, 110 more than the previous one. The links to more than 80 databases have been updated and 25 obsolete databases have been removed from the list. The complete database list and summaries are available online at the Nucleic Acids Research web site, http://nar.oxfordjournals.org/.

  18. Shark Mark Recapture Database (MRDBS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Shark Mark Recapture Database is a Cooperative Research Program database system used to keep multispecies mark-recapture information in a common format for...

  19. Children's Culture Database (CCD)

    DEFF Research Database (Denmark)

    Wanting, Birgit

    a Dialogue inspired database with documentation, network (individual and institutional profiles) and current news , paper presented at the research seminar: Electronic access to fiction, Copenhagen, November 11-13, 1996...

  20. IVR RSA Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This database contains trip-level reports submitted by vessels participating in Research Set-Aside projects with IVR reporting requirements.

  1. Research on the Index of MySQL Database%MySQL数据库索引的研究

    Institute of Scientific and Technical Information of China (English)

    王贵生

    2014-01-01

    Database index is the key data structure for improving the speed of data retrieval. In this paper, we analyze the index principle by combining with the principle of external storage and the B-tree structure of the database. We analyze of the reasons why many databases using B+tree as the index structure. And we analyze the advantages and disadvantages of MySQL database index in the InnoDB storage engine.%数据库索引是用于提高数据检索速度的关键数据结构,该文结合常用的数据库索引结构B树,分析索引的原理,并结合外存储的原理,分析大多数数据库使用B+树作为索引结构的原因,并结合MySQL数据库中InnoDB存储引擎中的索引实现,分析其优缺点。

  2. The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case–control study using the UK General Practice Research Database

    OpenAIRE

    Skow, A.; Douglas, I.; Smeeth, L.

    2013-01-01

    AIM: To investigate whether the use of carbamazepine is associated with reduced risk of Parkinson's disease. METHODS: We conducted a population-based matched case-control study of patients randomly selected from the UK General Research Practice Database (GPRD). We identified 8,549 patients with Parkinson's disease using diagnosis criteria with a positive predictive value of 90%. These patients were compared with 42,160 controls matched for age, sex, and general practice. RESULTS: Overall, 3.0...

  3. Database Manager

    Science.gov (United States)

    Martin, Andrew

    2010-01-01

    It is normal practice today for organizations to store large quantities of records of related information as computer-based files or databases. Purposeful information is retrieved by performing queries on the data sets. The purpose of DATABASE MANAGER is to communicate to students the method by which the computer performs these queries. This…

  4. Development of a database for prompt gamma-ray neutron activation analysis: Summary report of the third research coordination meeting

    Energy Technology Data Exchange (ETDEWEB)

    Lindstrom, Richard M.; Firestone, Richard B.; Pavi, ???

    2003-04-01

    The main discussions and conclusions from the Third Co-ordination Meeting on the Development of a Database for Prompt Gamma-ray Neutron Activation Analysis are summarized in this report. All results were reviewed in detail, and the final version of the TECDOC and the corresponding software were agreed upon and approved for preparation. Actions were formulated with the aim of completing the final version of the TECDOC and associated software by May 2003.

  5. Transition Plan For Moving AFOMS Occupational Analysis Report Contents to AFPC’s Human Resources Research Database

    Science.gov (United States)

    2008-09-20

    its current configuration MTISurv Utilities will not reverse the conversion to ORACLE ( Metrica , 2002), but it could be modified, or an alternative...improving formal course content ( Metrica , 2000; Teachout, Sego & Ford, 1995; Teachout, Sego, & Olea, 1993). The conceptual foundation of TEEM is that in...Database and Delivering Data for Analysis. Randolph AFB TX: AFOMS/OAV. Metrica , Inc. (2002, Jan). MTISurv Installation Instructions and User’s

  6. 计算机数据库安全管理研究%Research on Security Management of Computer Database

    Institute of Scientific and Technical Information of China (English)

    石玉芳

    2015-01-01

    近年来,随着科学技术的快速发展,计算机的广泛应用给人们的日常生活工作带来翻天覆地的变化,但计算机自身系统也在不断地完善,存在着一定的缺陷与问题,尤其是技术及数据库的安全问题。计算机数据库作为计算机系统操作数据以及存储的形式,作为计算机数据系统的重要组成环节,它的安全问题直接关系到整个计算机数据系统未来的发展。该文从计算机数据库安全管理等方面入手,针对目前计算机数据库安全管理的现状以及存在的问题,提出几点有效的建议和措施,从而提高计算机数据库安全管理水平。%in recent years, with the rapid development of science and technology, the extensive application of the computer to the people's daily life and work bring earth shaking changes, but the computer system also in the continuous improvement, there is a certain defects and problems, especially the problem of database technology and safety. Computer database as a computer system data manipulation and storage form, as an important part of the computer data system and its security problems directly related to the computer data of the future development of the system. The from the computer database security management of aiming at the status quo and the existing problems of safety management of computer database, puts forward some effective suggestions and mea⁃sures, so as to improve the safety management level of computer database.

  7. The Tinnitus Research Initiative (TRI database: A new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome

    Directory of Open Access Journals (Sweden)

    Staudinger Susanne

    2010-08-01

    database currently contains data from more than 400 patients. It is expected that more centers will join the project and that the patient numbers will rapidly grow, so that this international database will further facilitate future research and contribute to the development of evidence based on individualized treatment.

  8. A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology

    Directory of Open Access Journals (Sweden)

    Huang Xiangning

    2001-02-01

    Full Text Available Abstract Background An association between mumps-measles-rubella (MMR vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to considerable concern about the safety of the vaccine. Methods A matched case-control study using data derived form the United Kingdom General Practice Research Database. Children with a possible diagnosis of autism will be identified from their electronic health records. All diagnoses will be validated by a detailed review of hospital letters and by using information derived from a parental questionnaire. Ten controls per case will be selected from the database. Conditional logistic regression will be used to assess the association between MMR vaccination and autism. In addition case series analyses will be undertaken to estimate the relative incidence of onset of autism in defined time intervals after vaccination. The study is funded by the United Kingdom Medical Research Council. Discussion Electronic health databases offer tremendous opportunities for evaluating the adverse effects of vaccines. However there is much scope for bias and confounding. The rigorous validation of all diagnoses and the collection of additional information by parental questionnaire in this study are essential to minimise the possibility of misleading results.

  9. The Danish Testicular Cancer database

    DEFF Research Database (Denmark)

    Daugaard, Gedske; Kier, Maria Gry Gundgaard; Bandak, Mikkel

    2016-01-01

    AIM: The nationwide Danish Testicular Cancer database consists of a retrospective research database (DaTeCa database) and a prospective clinical database (Danish Multidisciplinary Cancer Group [DMCG] DaTeCa database). The aim is to improve the quality of care for patients with testicular cancer (TC......) in Denmark, that is, by identifying risk factors for relapse, toxicity related to treatment, and focusing on late effects. STUDY POPULATION: All Danish male patients with a histologically verified germ cell cancer diagnosis in the Danish Pathology Registry are included in the DaTeCa databases. Data...

  10. Clinical databases in physical therapy.

    NARCIS (Netherlands)

    Swinkels, I.C.; Ende, C.H.M. van den; Bakker, D. de; Wees, P.J. van der; Hart, D.L.; Deutscher, D.; Bosch, W.J.H.M. van den; Dekker, J.

    2007-01-01

    Clinical databases in physical therapy provide increasing opportunities for research into physical therapy theory and practice. At present, information on the characteristics of existing databases is lacking. The purpose of this study was to identify clinical databases in which physical therapists r

  11. Clinical databases in physical therapy.

    NARCIS (Netherlands)

    Swinkels, I.C.; Ende, C.H.M. van den; Bakker, D. de; Wees, P.J. van der; Hart, D.L.; Deutscher, D.; Bosch, W.J.H.M. van den; Dekker, J.

    2007-01-01

    Clinical databases in physical therapy provide increasing opportunities for research into physical therapy theory and practice. At present, information on the characteristics of existing databases is lacking. The purpose of this study was to identify clinical databases in which physical therapists

  12. Database Replication

    CERN Document Server

    Kemme, Bettina

    2010-01-01

    Database replication is widely used for fault-tolerance, scalability and performance. The failure of one database replica does not stop the system from working as available replicas can take over the tasks of the failed replica. Scalability can be achieved by distributing the load across all replicas, and adding new replicas should the load increase. Finally, database replication can provide fast local access, even if clients are geographically distributed clients, if data copies are located close to clients. Despite its advantages, replication is not a straightforward technique to apply, and

  13. Probabilistic Databases

    CERN Document Server

    Suciu, Dan; Koch, Christop

    2011-01-01

    Probabilistic databases are databases where the value of some attributes or the presence of some records are uncertain and known only with some probability. Applications in many areas such as information extraction, RFID and scientific data management, data cleaning, data integration, and financial risk assessment produce large volumes of uncertain data, which are best modeled and processed by a probabilistic database. This book presents the state of the art in representation formalisms and query processing techniques for probabilistic data. It starts by discussing the basic principles for rep

  14. Dealer Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The dealer reporting databases contain the primary data reported by federally permitted seafood dealers in the northeast. Electronic reporting was implemented May 1,...

  15. National database

    DEFF Research Database (Denmark)

    Kristensen, Helen Grundtvig; Stjernø, Henrik

    1995-01-01

    Artikel om national database for sygeplejeforskning oprettet på Dansk Institut for Sundheds- og Sygeplejeforskning. Det er målet med databasen at samle viden om forsknings- og udviklingsaktiviteter inden for sygeplejen.......Artikel om national database for sygeplejeforskning oprettet på Dansk Institut for Sundheds- og Sygeplejeforskning. Det er målet med databasen at samle viden om forsknings- og udviklingsaktiviteter inden for sygeplejen....

  16. The Danish Depression Database

    DEFF Research Database (Denmark)

    Videbech, Poul Bror Hemming; Deleuran, Anette

    2016-01-01

    AIM OF DATABASE: The purpose of the Danish Depression Database (DDD) is to monitor and facilitate the improvement of the quality of the treatment of depression in Denmark. Furthermore, the DDD has been designed to facilitate research. STUDY POPULATION: Inpatients as well as outpatients...... as an evaluation of the risk of suicide are measured before and after treatment. Whether psychiatric aftercare has been scheduled for inpatients and the rate of rehospitalization are also registered. DESCRIPTIVE DATA: The database was launched in 2011. Every year since then ~5,500 inpatients and 7,500 outpatients...... have been registered annually in the database. A total of 24,083 inpatients and 29,918 outpatients have been registered. The DDD produces an annual report published on the Internet. CONCLUSION: The DDD can become an important tool for quality improvement and research, when the reporting is more...

  17. The International Nucleotide Sequence Database Collaboration

    Science.gov (United States)

    Cochrane, Guy; Karsch-Mizrachi, Ilene; Takagi, Toshihisa; Sequence Database Collaboration, International Nucleotide

    2016-01-01

    The International Nucleotide Sequence Database Collaboration (INSDC; http://www.insdc.org) comprises three global partners committed to capturing, preserving and providing comprehensive public-domain nucleotide sequence information. The INSDC establishes standards, formats and protocols for data and metadata to make it easier for individuals and organisations to submit their nucleotide data reliably to public archives. This work enables the continuous, global exchange of information about living things. Here we present an update of the INSDC in 2015, including data growth and diversification, new standards and requirements by publishers for authors to submit their data to the public archives. The INSDC serves as a model for data sharing in the life sciences. PMID:26657633

  18. Research and implementation of database security protocol%数据库安全协议研究与实现

    Institute of Scientific and Technical Information of China (English)

    凃云杰

    2016-01-01

    With provision for the multiple access modes of Cache database,the Antlr grammar generating tool is used to convert the Cache object script grammar and SQL script grammar into the intermediate representation language,so as to set the uniform audit rule. The main functions of the system include Cache protocol analysis and Cache object script grammar transfor-mation mainly. The manual method is used to compile and collect massive test cases in realization process. It is determined that the protocol analysis module can play a role in security audit of Cache database.%鉴于Cache数据库多种访问方式,利用Antlr语法产生工具完成Cache对象脚本语法和SQL脚本语法向中间表示语言的转换以便于设置统一的审计规则.该系统的主要功能包括Cache协议分析和Cache对象脚本语法转换等.在实现过程中用人工方法编写和收集大量测试用例,确定了协议分析模块能够起到对Cache数据库进行安全审计的作用.

  19. Specialist Bibliographic Databases.

    Science.gov (United States)

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Voronov, Alexander A; Trukhachev, Vladimir I; Kostyukova, Elena I; Gerasimov, Alexey N; Kitas, George D

    2016-05-01

    Specialist bibliographic databases offer essential online tools for researchers and authors who work on specific subjects and perform comprehensive and systematic syntheses of evidence. This article presents examples of the established specialist databases, which may be of interest to those engaged in multidisciplinary science communication. Access to most specialist databases is through subscription schemes and membership in professional associations. Several aggregators of information and database vendors, such as EBSCOhost and ProQuest, facilitate advanced searches supported by specialist keyword thesauri. Searches of items through specialist databases are complementary to those through multidisciplinary research platforms, such as PubMed, Web of Science, and Google Scholar. Familiarizing with the functional characteristics of biomedical and nonbiomedical bibliographic search tools is mandatory for researchers, authors, editors, and publishers. The database users are offered updates of the indexed journal lists, abstracts, author profiles, and links to other metadata. Editors and publishers may find particularly useful source selection criteria and apply for coverage of their peer-reviewed journals and grey literature sources. These criteria are aimed at accepting relevant sources with established editorial policies and quality controls.

  20. Development and application of a database of food ingredient fraud and economically motivated adulteration from 1980 to 2010.

    Science.gov (United States)

    Moore, Jeffrey C; Spink, John; Lipp, Markus

    2012-04-01

    Food ingredient fraud and economically motivated adulteration are emerging risks, but a comprehensive compilation of information about known problematic ingredients and detection methods does not currently exist. The objectives of this research were to collect such information from publicly available articles in scholarly journals and general media, organize into a database, and review and analyze the data to identify trends. The results summarized are a database that will be published in the US Pharmacopeial Convention's Food Chemicals Codex, 8th edition, and includes 1305 records, including 1000 records with analytical methods collected from 677 references. Olive oil, milk, honey, and saffron were the most common targets for adulteration reported in scholarly journals, and potentially harmful issues identified include spices diluted with lead chromate and lead tetraoxide, substitution of Chinese star anise with toxic Japanese star anise, and melamine adulteration of high protein content foods. High-performance liquid chromatography and infrared spectroscopy were the most common analytical detection procedures, and chemometrics data analysis was used in a large number of reports. Future expansion of this database will include additional publically available articles published before 1980 and in other languages, as well as data outside the public domain. The authors recommend in-depth analyses of individual incidents. This report describes the development and application of a database of food ingredient fraud issues from publicly available references. The database provides baseline information and data useful to governments, agencies, and individual companies assessing the risks of specific products produced in specific regions as well as products distributed and sold in other regions. In addition, the report describes current analytical technologies for detecting food fraud and identifies trends and developments. © 2012 US Pharmacupia Journal of Food Science

  1. Legacy2Drupal - Conversion of an existing oceanographic relational database to a semantically enabled Drupal content management system

    Science.gov (United States)

    Maffei, A. R.; Chandler, C. L.; Work, T.; Allen, J.; Groman, R. C.; Fox, P. A.

    2009-12-01

    Content Management Systems (CMSs) provide powerful features that can be of use to oceanographic (and other geo-science) data managers. However, in many instances, geo-science data management offices have previously designed customized schemas for their metadata. The WHOI Ocean Informatics initiative and the NSF funded Biological Chemical and Biological Data Management Office (BCO-DMO) have jointly sponsored a project to port an existing, relational database containing oceanographic metadata, along with an existing interface coded in Cold Fusion middleware, to a Drupal6 Content Management System. The goal was to translate all the existing database tables, input forms, website reports, and other features present in the existing system to employ Drupal CMS features. The replacement features include Drupal content types, CCK node-reference fields, themes, RDB, SPARQL, workflow, and a number of other supporting modules. Strategic use of some Drupal6 CMS features enables three separate but complementary interfaces that provide access to oceanographic research metadata via the MySQL database: 1) a Drupal6-powered front-end; 2) a standard SQL port (used to provide a Mapserver interface to the metadata and data; and 3) a SPARQL port (feeding a new faceted search capability being developed). Future plans include the creation of science ontologies, by scientist/technologist teams, that will drive semantically-enabled faceted search capabilities planned for the site. Incorporation of semantic technologies included in the future Drupal 7 core release is also anticipated. Using a public domain CMS as opposed to proprietary middleware, and taking advantage of the many features of Drupal 6 that are designed to support semantically-enabled interfaces will help prepare the BCO-DMO database for interoperability with other ecosystem databases.

  2. FEEDBACK ON A PUBLICLY DISTRIBUTED IMAGE DATABASE: THE MESSIDOR DATABASE

    Directory of Open Access Journals (Sweden)

    Etienne Decencière

    2014-08-01

    Full Text Available The Messidor database, which contains hundreds of eye fundus images, has been publicly distributed since 2008. It was created by the Messidor project in order to evaluate automatic lesion segmentation and diabetic retinopathy grading methods. Designing, producing and maintaining such a database entails significant costs. By publicly sharing it, one hopes to bring a valuable resource to the public research community. However, the real interest and benefit of the research community is not easy to quantify. We analyse here the feedback on the Messidor database, after more than 6 years of diffusion. This analysis should apply to other similar research databases.

  3. A Multidimensional Rasch Analysis of the Functional Independence Measure Based on the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database.

    Science.gov (United States)

    Pretz, Christopher R; Kean, Jacob; Heinemann, Allen W; Kozlowski, Allan J; Bode, Rita K; Gebhardt, Eveline

    2016-07-15

    A number of studies have evaluated the psychometric properties of the Functional Independence Measure (FIM™) using Rasch analysis, although none has done so using the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database, a longitudinal database that captures demographic and outcome information on persons with moderate to severe traumatic brain injury across the United States. In the current study, we examine the psychometric properties of the FIM as represented by persons within this database and demonstrate that the FIM comprises three subscales representing cognitive, self-care, and mobility domains. These subscales were analyzed simultaneously using a multivariate Rasch model in combination with a time dependent concurrent calibration scheme with the goal of creating a raw score-to-logit transformation that can be used to improve the accuracy of parametric statistical analyses. The bowel and bladder function items were removed because of misfit with the motor and cognitive items. Some motor items exhibited step disorder, which was addressed by collapsing Categories 1-3 for Toileting, Stairs, Locomotion, Tub/Shower Transfers; Categories 1 and 2 for Toilet and Bed Transfers; and Categories 2 and 3 for Grooming. The strong correlations (r = 0.82-0.96) among the three subscales suggest they should be modeled together. Coefficient alpha of 0.98 indicates high internal consistency. Keyform maps are provided to enhance clinical interpretation and application of study results.

  4. Challenges of molecular nutrition research 6: The nutritional phenotype database to store, share and evaluate nutritional systems biology studies

    NARCIS (Netherlands)

    Ommen, B. van; Bouwman, J.; Dragsted, L.O.; Drevon, C.A.; Elliott, R.; Groot, P. de; Kaput, J.; Mathers, J.C.; Müller, M.; Pepping, F.; Saito, J.; Scalbert, A.; Radonjic, M.; Rocca-Serra, P.; Travis, A.; Wopereis, S.; Evelo, C.T.

    2010-01-01

    The challenge of modern nutrition and health research is to identify food-based strategies promoting life-long optimal health and well-being. This research is complex because it exploits a multitude of bioactive compounds acting on an extensive network of interacting processes. Whereas nutrition res

  5. Challenges of molecular nutrition research 6: The nutritional phenotype database to store, share and evaluate nutritional systems biology studies

    NARCIS (Netherlands)

    Ommen, B. van; Bouwman, J.; Dragsted, L.O.; Drevon, C.A.; Elliott, R.; Groot, P. de; Kaput, J.; Mathers, J.C.; Müller, M.; Pepping, F.; Saito, J.; Scalbert, A.; Radonjic, M.; Rocca-Serra, P.; Travis, A.; Wopereis, S.; Evelo, C.T.

    2010-01-01

    The challenge of modern nutrition and health research is to identify food-based strategies promoting life-long optimal health and well-being. This research is complex because it exploits a multitude of bioactive compounds acting on an extensive network of interacting processes. Whereas nutrition

  6. PADB : Published Association Database

    Directory of Open Access Journals (Sweden)

    Lee Jin-Sung

    2007-09-01

    Full Text Available Abstract Background Although molecular pathway information and the International HapMap Project data can help biomedical researchers to investigate the aetiology of complex diseases more effectively, such information is missing or insufficient in current genetic association databases. In addition, only a few of the environmental risk factors are included as gene-environment interactions, and the risk measures of associations are not indexed in any association databases. Description We have developed a published association database (PADB; http://www.medclue.com/padb that includes both the genetic associations and the environmental risk factors available in PubMed database. Each genetic risk factor is linked to a molecular pathway database and the HapMap database through human gene symbols identified in the abstracts. And the risk measures such as odds ratios or hazard ratios are extracted automatically from the abstracts when available. Thus, users can review the association data sorted by the risk measures, and genetic associations can be grouped by human genes or molecular pathways. The search results can also be saved to tab-delimited text files for further sorting or analysis. Currently, PADB indexes more than 1,500,000 PubMed abstracts that include 3442 human genes, 461 molecular pathways and about 190,000 risk measures ranging from 0.00001 to 4878.9. Conclusion PADB is a unique online database of published associations that will serve as a novel and powerful resource for reviewing and interpreting huge association data of complex human diseases.

  7. Harmonization of Databases

    DEFF Research Database (Denmark)

    Charlifue, Susan; Tate, Denise; Biering-Sorensen, Fin

    2016-01-01

    The objectives of this article are to (1) provide an overview of existing spinal cord injury (SCI) clinical research databases-their purposes, characteristics, and accessibility to users; and (2) present a vision for future collaborations required for cross-cutting research in SCI. This vision...... strengths and weaknesses. Efforts to provide a uniform approach to data collection are also reviewed. The databases reviewed offer different approaches to capture important clinical information on SCI. They vary on size, purpose, data points, inclusion of standard outcomes, and technical requirements. Each...... highlights the need for validated and relevant data for longitudinal clinical trials and observational and epidemiologic SCI-related studies. Three existing SCI clinical research databases/registries are reviewed and summarized with regard to current formats, collection methods, and uses, including major...

  8. Print: University of Gaziantep Press. Abstracted and Indexed in: ULAKBİM national index EBSCO Host database Indexcopernius index Akademia Sosyal Bilimler Indeksi ERGO ( Educational Research Global Observary NewJour Türk Eğitim İndeks

    Directory of Open Access Journals (Sweden)

    2013-06-01

    Full Text Available ed and Indexed in: ULAKBİM national index EBSCO Host database Indexcopernius index Akademia Sosyal Bilimler Indeksi ERGO ( Educational Research Global Observary NewJour Türk Eğitim İndeks

  9. Database Description - RPD | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available ation: National Institute of Crop Science, National Agriculture and Food Research Organization Journal Searc...titute of Crop Science, National Agriculture and Food Research Organization Setsuko Komatsu E-mail: Database

  10. 报刊公共领域与邹韬奋%The public domain of newspaper and journal and Zou Taofen

    Institute of Scientific and Technical Information of China (English)

    董亚秋

    2012-01-01

      众所周知,邹韬奋是我国卓越的新闻记者、出版家,更是一名进步爱国的政论家。他主编的《生活》周刊、《大众生活》和《全民抗战》刊物,由于其客观的立场、报刊的公共性和其注重与读者平等的讨论,构成了报刊公共领域。作为这一公共领域中的发言人角色,邹韬奋积极发表新闻评论,设立读者信箱和小言论等精品栏目,与读者和同仁进行交流。这些编辑出版活动充分展现了邹韬奋在报刊公共空间中的舆论引导作用。%  As we all know, Zou Tao-fen is an excellent journalist, publishing house, was a progressive patriotic political commentators. He published in life magazine, the public and the National Journal of the war, due to its objective of publicity and its focus on position, press and reader discussions on an equal footing, forming the newspaper of the public domain. Role as spokesman in this public area, Zou Tao-fen news positive comments, set up reader mail and small boutique, such as columns, communicate with colleagues and readers. These activities have fully demonstrated Zou taofen's editing and publishing in the newspaper public opinion to guide the role of the public space.

  11. Replacing the wild type loxP site in BACs from the public domain with lox66 using a lox66 transposon

    Directory of Open Access Journals (Sweden)

    Stennett Naima

    2010-02-01

    Full Text Available Abstract Background Chromatin adjoining the site of integration of a transgene affects expression and renders comparisons of closely related transgenes, such as those derived from a BAC deletion series retrofitted with enhancer-traps, unreliable. Gene targeting to a pre-determined site on the chromosome is likely to alleviate the problem. Findings A general procedure to replace the loxP site located at one end of genomic DNA inserts in BACs with lox66 is described. Truncating insert DNA from the loxP end with a Tn10 transposon carrying a lox66 site simultaneously substitutes the loxP with a lox66 sequence. The replacement occurs with high stringency, and the procedure should be applicable to all BACs in the public domain. Cre recombination of loxP with lox66 or lox71 was found to be as efficient as another loxP site during phage P1 transduction of small plasmids containing those sites. However the end-deletion of insert DNA in BACs using a lox66 transposon occurred at no more than 20% the efficiency observed with a loxP transposon. Differences in the ability of Cre protein available at different stages of the P1 life cycle to recombine identical versus non-identical lox-sites is likely responsible for this discrepancy. A possible mechanism to explain these findings is discussed. Conclusions The loxP/lox66 replacement procedure should allow targeting BACs to a pre-positioned lox71 site in zebrafish chromosomes; a system where homologous recombination-mediated "knock-in" technology is unavailable.

  12. DRAG: a database for recognition and analasys of gait

    Science.gov (United States)

    Kuchi, Prem; Hiremagalur, Raghu Ram V.; Huang, Helen; Carhart, Michael; He, Jiping; Panchanathan, Sethuraman

    2003-11-01

    A novel approach is proposed for creating a standardized and comprehensive database for gait analysis. The field of gait analysis is gaining increasing attention for applications such as visual surveillance, human-computer interfaces, and gait recognition and rehabilitation. Numerous algorithms have been developed for analyzing and processing gait data; however, a standard database for their systematic evaluation does not exist. Instead, existing gait databases consist of subsets of kinematic, kinetic, and electromyographic activity recordings by different investigators, at separate laboratories, and under varying conditions. Thus, the existing databases are neither homogenous nor sufficiently populated to statistically validate the algorithms. In this paper, a methodology for creating a database is presented, which can be used as a common ground to test the performance of algorithms that rely upon external marker data, ground reaction loading data, and/or video images. The database consists of: (1) synchronized motion-capture data (3D marker data) obtained using external markers, (2) computed joint angles, and (3) ground reaction loading acquired with plantar pressure insoles. This database could be easily expanded to include synchronized video, which will facilitate further development of video-based algorithms for motion tracking. This eventually could lead to the realization of markerless gait tracking. Such a system would have extensive applications in gait recognition, as well as gait rehabilitation. The entire database (marker, angle, and force data) will be placed in the public domain, and made available for downloads over the World Wide Web.

  13. The impact of standardizing the definition of visits on the consistency of multi-database observational health research

    National Research Council Canada - National Science Library

    Voss, Erica A; Ma, Qianli; Ryan, Patrick B

    2015-01-01

    Use of administrative claims from multiple sources for research purposes is challenged by the lack of consistency in the structure of the underlying data and definition of data across claims data providers...

  14. Development of a Cost-Effective Database Software for Psychiatric Research: A Study From Tertiary Care Teaching Hospital

    OpenAIRE

    Sabu Karakkamandapam; Narayanan Sree Kumaran Nair; PSVN Sharma

    2010-01-01

    Background: Technological progression made drastic changes in health care. Still there is a growing concern about proper utilization of health information within hospitals for various research activities. Huge volumes of such health information in majority of hospitals are redundant due to lack of appropriate and cost-effective technological tools for retrieving relevant health information for research purpose. Objective: To develop a cost-effective and user-friendly computerized medical reco...

  15. The Research and Design of MS SQL Database in Intelligent Buildings%智能楼宇中MS SQL数据库研究及设计

    Institute of Scientific and Technical Information of China (English)

    高天哲

    2011-01-01

    Intelligent Building Systems is created with the development of building systems, modem computer technology and information technology. It is convenient for daily life and businesses management. In this paper, the design and implementation of information systems based on MS SQL in the intelligent building is researched. First,the intelligent building systems and some knowledge of MS SQL is introduced, then the design and implementation of a database system is studied and a number of optimization meagre,about database system are researched.%智能楼宇系统是建筑系统与现代的计算机技术和信息技术相结合产生的。智能楼宇系统给日常生活和企业带来了便捷的管理方式。本文主要研究了智能楼宇系统中基于MS SQL数据库的信息系统的设计和实现。首先介绍了智能楼宇系统和MSSQL的一些知识。然后研究设计了数据库系统韵实现和数据库的一些优化措施。

  16. Glycoproteomic and glycomic databases.

    Science.gov (United States)

    Baycin Hizal, Deniz; Wolozny, Daniel; Colao, Joseph; Jacobson, Elena; Tian, Yuan; Krag, Sharon S; Betenbaugh, Michael J; Zhang, Hui

    2014-01-01

    Protein glycosylation serves critical roles in the cellular and biological processes of many organisms. Aberrant glycosylation has been associated with many illnesses such as hereditary and chronic diseases like cancer, cardiovascular diseases, neurological disorders, and immunological disorders. Emerging mass spectrometry (MS) technologies that enable the high-throughput identification of glycoproteins and glycans have accelerated the analysis and made possible the creation of dynamic and expanding databases. Although glycosylation-related databases have been established by many laboratories and institutions, they are not yet widely known in the community. Our study reviews 15 different publicly available databases and identifies their key elements so that users can identify the most applicable platform for their analytical needs. These databases include biological information on the experimentally identified glycans and glycopeptides from various cells and organisms such as human, rat, mouse, fly and zebrafish. The features of these databases - 7 for glycoproteomic data, 6 for glycomic data, and 2 for glycan binding proteins are summarized including the enrichment techniques that are used for glycoproteome and glycan identification. Furthermore databases such as Unipep, GlycoFly, GlycoFish recently established by our group are introduced. The unique features of each database, such as the analytical methods used and bioinformatical tools available are summarized. This information will be a valuable resource for the glycobiology community as it presents the analytical methods and glycosylation related databases together in one compendium. It will also represent a step towards the desired long term goal of integrating the different databases of glycosylation in order to characterize and categorize glycoproteins and glycans better for biomedical research.

  17. Research of Database Based on NoSQL%基于NoSQL的数据库技术分析

    Institute of Scientific and Technical Information of China (English)

    权治; 宋晶晶

    2013-01-01

    由于Web2.0的快速发展,非关系型、分布式数据存储得到了快速的发展.针对传统关系型数据库逐渐暴露出的性能瓶颈,介绍了非关系型数据库(Non_ relational Database,NoSQL)模型及NoSQL数据库,对NoSQL数据库具有的特点做了简单定义,阐述了NoSQL数据库的存储方式,论证了NoSQL比较于传统关系数据库的优点,并介绍了著名的CAP理论.针对NoSQL的大数据量存储机制,总结了主流解决方案的共同特点及共同技术,并对数据库的性能测试结果进行了分析.

  18. Developing a national database to recent Hispanic/minority graduates and professionals for employmnet, procurement, consulting, and educational research opportunities with the federal government. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Keller, G.D.; Garza, H.

    1996-09-30

    This report very briefly summarizes notable accomplishments of the grant collaboration between the Hispanic Experts Database/Minority Experts Database and the American Council on Education. The Directory of Hispanic Experts was compiled and distributed from the database. The database was expanded through several initiatives, and information dissemination was increased. The database is now available on the Internet and the World Wide Web. Restructuring of Web sites and other means of information dissemination was performed to coordinate the database with other government databases and eliminate duplication.

  19. Food traceability systems in China: The current status of and future perspectives on food supply chain databases, legal support, and technological research and support for food safety regulation.

    Science.gov (United States)

    Tang, Qi; Li, Jiajia; Sun, Mei; Lv, Jun; Gai, Ruoyan; Mei, Lin; Xu, Lingzhong

    2015-02-01

    Over the past few decades, the field of food security has witnessed numerous problems and incidents that have garnered public attention. Given this serious situation, the food traceability system (FTS) has become part of the expanding food safety continuum to reduce the risk of food safety problems. This article reviews a great deal of the related literature and results from previous studies of FTS to corroborate this contention. This article describes the development and benefits of FTS in developed countries like the United States of America (USA), Japan, and some European countries. Problems with existing FTS in China are noted, including a lack of a complete database, inadequate laws and regulations, and lagging technological research into FTS. This article puts forward several suggestions for the future, including improvement of information websites, clarification of regulatory responsibilities, and promotion of technological research.

  20. Replikasi Unidirectional pada Heterogen Database

    Directory of Open Access Journals (Sweden)

    Hendro Nindito

    2013-12-01

    Full Text Available The use of diverse database technology in enterprise today can not be avoided. Thus, technology is needed to generate information in real time. The purpose of this research is to discuss a database replication technology that can be applied in heterogeneous database environments. In this study we use Windows-based MS SQL Server database to Linux-based Oracle database as the goal. The research method used is prototyping where development can be done quickly and testing of working models of the interaction process is done through repeated. From this research it is obtained that the database replication technolgy using Oracle Golden Gate can be applied in heterogeneous environments in real time as well.

  1. Cancer studies based on secondary data analysis of the Taiwan's National Health Insurance Research Database: A computational text analysis and visualization study.

    Science.gov (United States)

    Chiang, Jui-Kun; Lin, Chih-Wen; Wang, Chun-Lung; Koo, Malcolm; Kao, Yee-Hsin

    2017-04-01

    There has been a surge in the academic publication output based on secondary analyses of the data from the Taiwan's National Health Insurance claim records. It has become a challenge to comprehend such a rapid expansion of the literature. Therefore, this study aimed to explore the conceptual content of National Health Insurance Research Database-based cancer research, using the abstract of articles extracted from PubMed between 2002 and 2015. Search terms including "National Health Insurance Research Database (NHIRD) AND Taiwan," "Taiwan AND population-based," and "Taiwan AND nationwide" were used to search in PubMed with the publication date limited to between 1997 and 2015. The retrieved articles were manually screened to retain only those that were cancer-related and were based on secondary data analysis of the NHIRD. A total 589 articles were selected for subsequent text mining using the R software. Among the 589 articles, the top 5 most studied cancer types were breast (16.3%), lung (11.4%), colorectal (10.4%), liver (8.3%), and prostate (7.5%). The articles that received the highest number of citations by PubMed Central articles were cited 92 times. The top 3 most frequently occurred keywords in the abstracts of the 589 articles were cancer, patient, and risk, with 3670, 2535, and 1652 times, respectively. Analysis of key conception indicated that the most common conceptions were diabetes, survival, breast cancer, lung cancer, and colorectal cancer. In conclusion, in this study of 589 published articles on secondary data analysis of the NHIRD, indexed by PubMed between 2002 and 2015, we found that while the risk factors of cancer, treatment of cancer, and survival of cancer patients were popular research topics, end-of-life cancer care issues were less studied. Further studies should explore these areas since they are as important as treatment of the disease itself for many patients.

  2. Establishment of the Database for Medical Scientiifc Researches%医学科研数据仓库的建设

    Institute of Scientific and Technical Information of China (English)

    翟凤杰; 费晓璐; 洪松林; 庄映辉

    2013-01-01

    应用面向主题的数据仓库技术,将我院现有的电子化业务数据中有关临床医学的海量数据进行整合,以集成的电子化数据形成医学科研的专用数据仓库。利用该独立的医学科研数据仓库,使得科研人员可对历史的全部海量数据进行在线的、实时的、深入的分析,挖掘和共享临床科研数据,帮助提高各级医学技术人员的科研能力和效率。%Application of the subject-oriented data base technology contributes to integration of massive clinical medical data derived from the current digital business data base of the hospital as well as construction of the special data base for medical scientiifc researches. The independent and integrated data base for medical scientiifc researches provides the researchers with a platform to implement on-line, real-time and in-depth analysis on the massive historical data. Mining and sharing the clinical research data will help to improve the ability and efifciency of scientiifc researches for medical technical personnel at all levels.

  3. Causes and risk factors for death in systemic sclerosis : a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

    NARCIS (Netherlands)

    Tyndall, Anthony J.; Bannert, Bettina; Vonk, Madelon; Airo, Paolo; Cozzi, Franco; Carreira, Patricia E.; Bancel, Dominique Farge; Allanore, Yannick; Mueller-Ladner, Ulf; Distler, Oliver; Iannone, Florenzo; Pellerito, Raffaele; Pileckyte, Margarita; Miniati, Irene; Ananieva, Lidia; Gurman, Alexandra Balbir; Damjanov, Nemanja; Mueller, Adelheid; Valentini, Gabriele; Riemekasten, Gabriela; Tikly, Mohammed; Hummers, Laura; Henriques, Maria J. S.; Caramaschi, Paola; Scheja, Agneta; Rozman, Blaz; Ton, Evelien; Kumanovics, Gabor; Coleiro, Bernard; Feierl, Eva; Szucs, Gabriella; Von Muehlen, Carlos Alberto; Riccieri, Valeria; Novak, Srdan; Chizzolini, Carlo; Kotulska, Anna; Denton, Christopher; Coelho, Paulo C.; Koetter, Ina; Simsek, Ismail; de la Pena Lefebvre, Paloma Garcia; Hachulla, Eric; Seibold, James R.; Rednic, Simona; Stork, Jiri; Morovic-Vergles, Jadranka; Walker, Ulrich A.

    2010-01-01

    Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc). Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centre

  4. Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database

    OpenAIRE

    Walker, U.; A. Tyndall; Czirják, L; Denton, C.; Farge-Bancel, D.; Kowal-Bielecka, O.; Müller-Ladner, U; Bocelli-Tyndall, C.; Matucci-Cerinic, M; Ribi, Camillo; Chizzolini, Carlo; EUSTAR Group

    2007-01-01

    Systemic sclerosis (SSc) is a multisystem autoimmune disease, which is classified into a diffuse cutaneous (dcSSc) and a limited cutaneous (lcSSc) subset according to the skin involvement. In order to better understand the vascular, immunological and fibrotic processes of SSc and to guide its treatment, the EULAR Scleroderma Trials And Research (EUSTAR) group was formed in June 2004.

  5. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database.

    NARCIS (Netherlands)

    Tyndall, A.J.; Bannert, B.; Vonk, M.C.; Airo, P.; Cozzi, F.; Carreira, P.E.; Bancel, D.F.; Allanore, Y.; Muller-Ladner, U.; Distler, O.; Iannone, F.; Pellerito, R.; Pileckyte, M.; Miniati, I.; Ananieva, L.; Gurman, A.B.; Damjanov, N.; Mueller, A.; Valentini, G.; Riemekasten, G.; Tikly, M.; Hummers, L.; Henriques, M.J.; Caramaschi, P.; Scheja, A.; Rozman, B.; Ton, E.; Kumanovics, G.; Coleiro, B.; Feierl, E.; Szucs, G.; Muhlen, C.A. Von; Riccieri, V.; Novak, S.; Chizzolini, C.; Kotulska, A.; Denton, C.; Coelho, P.C.; Kotter, I.; Simsek, I.; Pena Lefebvre, P.G. de la; Hachulla, E.; Seibold, J.R.; Rednic, S.; Stork, J.; Morovic-Vergles, J.; Walker, U.A.

    2010-01-01

    OBJECTIVES: To determine the causes and predictors of mortality in systemic sclerosis (SSc). METHODS: Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR

  6. The history of the USDA Nematode Collection and its database: valuable resources for taxonomic research and identification

    Science.gov (United States)

    The United States Department of Agriculture Nematode Collection continues to serve as one of the largest and most comprehensive nematode repositories in the world. Nematology research in the United States began in the late 1800’s, and for many years the collections of the USDA nematologists remained...

  7. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database.

    NARCIS (Netherlands)

    Tyndall, A.J.; Bannert, B.; Vonk, M.C.; Airo, P.; Cozzi, F.; Carreira, P.E.; Bancel, D.F.; Allanore, Y.; Muller-Ladner, U.; Distler, O.; Iannone, F.; Pellerito, R.; Pileckyte, M.; Miniati, I.; Ananieva, L.; Gurman, A.B.; Damjanov, N.; Mueller, A.; Valentini, G.; Riemekasten, G.; Tikly, M.; Hummers, L.; Henriques, M.J.; Caramaschi, P.; Scheja, A.; Rozman, B.; Ton, E.; Kumanovics, G.; Coleiro, B.; Feierl, E.; Szucs, G.; Muhlen, C.A. Von; Riccieri, V.; Novak, S.; Chizzolini, C.; Kotulska, A.; Denton, C.; Coelho, P.C.; Kotter, I.; Simsek, I.; Pena Lefebvre, P.G. de la; Hachulla, E.; Seibold, J.R.; Rednic, S.; Stork, J.; Morovic-Vergles, J.; Walker, U.A.

    2010-01-01

    OBJECTIVES: To determine the causes and predictors of mortality in systemic sclerosis (SSc). METHODS: Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR cent

  8. Identification of organization name variants in large databases using rule-based scoring and clustering: With a case study on the web of science database

    NARCIS (Netherlands)

    E.A.M. Caron (Emiel); H.A.M. Daniels (Hennie)

    2016-01-01

    textabstractThis research describes a general method to automatically clean organizational and business names variants within large databases, such as: patent databases, bibliographic databases, databases in business information systems, or any other database containing organisational name

  9. WMC Database Evaluation. Case Study Report

    Energy Technology Data Exchange (ETDEWEB)

    Palounek, Andrea P. T [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-29

    The WMC Database is ultimately envisioned to hold a collection of experimental data, design information, and information from computational models. This project was a first attempt at using the Database to access experimental data and extract information from it. This evaluation shows that the Database concept is sound and robust, and that the Database, once fully populated, should remain eminently usable for future researchers.

  10. The Danish Testicular Cancer database

    DEFF Research Database (Denmark)

    Daugaard, Gedske; Kier, Maria Gry Gundgaard; Bandak, Mikkel

    2016-01-01

    AIM: The nationwide Danish Testicular Cancer database consists of a retrospective research database (DaTeCa database) and a prospective clinical database (Danish Multidisciplinary Cancer Group [DMCG] DaTeCa database). The aim is to improve the quality of care for patients with testicular cancer (TC......) in Denmark, that is, by identifying risk factors for relapse, toxicity related to treatment, and focusing on late effects. STUDY POPULATION: All Danish male patients with a histologically verified germ cell cancer diagnosis in the Danish Pathology Registry are included in the DaTeCa databases. Data...... survivors alive on October 2014 were invited to fill in this questionnaire including 160 validated questions. Collection of questionnaires is still ongoing. A biobank including blood/sputum samples for future genetic analyses has been established. Both samples related to DaTeCa and DMCG DaTeCa database...

  11. Databases and data mining

    Science.gov (United States)

    Over the course of the past decade, the breadth of information that is made available through online resources for plant biology has increased astronomically, as have the interconnectedness among databases, online tools, and methods of data acquisition and analysis. For maize researchers, the numbe...

  12. 数据库原理与应用课程教学方法研究%Research in teaching method of database application

    Institute of Scientific and Technical Information of China (English)

    戚娜

    2012-01-01

    Access数据库原理与应用是高职计算机相关专业的一门专业基础课程,但在Access数据库教学的过程中,发现学生对Access数据库的理解与应用却不如人意。为了学生通过该课程的学习可以掌握一种数据库技术。本文采用实态调查、比较研究和归纳研究的方法对该课程的教学方法进行了研究,提出了新的教学方法和思路,达到提高教学效果的目的。%Access Database Application is an essential compulsory course for college students of computer related majors in vocational school, but in the teaching of Access, find students not well understand the course. Through the studying of this course, students master a technical of database, the paper uses the investigation, the comparative study and the inductive research, proposes a new teaching method and train of thought, achieve the purpose of improving teaching effectiveness.

  13. Djeen (Database for Joomla!’s Extensible Engine): a research information management system for flexible multi-technology project administration

    Science.gov (United States)

    2013-01-01

    Background With the advance of post-genomic technologies, the need for tools to manage large scale data in biology becomes more pressing. This involves annotating and storing data securely, as well as granting permissions flexibly with several technologies (all array types, flow cytometry, proteomics) for collaborative work and data sharing. This task is not easily achieved with most systems available today. Findings We developed Djeen (Database for Joomla!’s Extensible Engine), a new Research Information Management System (RIMS) for collaborative projects. Djeen is a user-friendly application, designed to streamline data storage and annotation collaboratively. Its database model, kept simple, is compliant with most technologies and allows storing and managing of heterogeneous data with the same system. Advanced permissions are managed through different roles. Templates allow Minimum Information (MI) compliance. Conclusion Djeen allows managing project associated with heterogeneous data types while enforcing annotation integrity and minimum information. Projects are managed within a hierarchy and user permissions are finely-grained for each project, user and group. Djeen Component source code (version 1.5.1) and installation documentation are available under CeCILL license from http://sourceforge.net/projects/djeen/files and supplementary material. PMID:23742665

  14. The Danish Depression Database

    Directory of Open Access Journals (Sweden)

    Videbech P

    2016-10-01

    Full Text Available Poul Videbech,1 Anette Deleuran2 1Mental Health Centre Glostrup, Department of Clinical Medicine, University of Copenhagen, Glostrup, 2Psychiatric Centre Amager, Copenhagen S, Denmark Aim of database: The purpose of the Danish Depression Database (DDD is to monitor and facilitate the improvement of the quality of the treatment of depression in Denmark. Furthermore, the DDD has been designed to facilitate research. Study population: Inpatients as well as outpatients with depression, aged above 18 years, and treated in the public psychiatric hospital system were enrolled. Main variables: Variables include whether the patient has been thoroughly somatically examined and has been interviewed about the psychopathology by a specialist in psychiatry. The Hamilton score as well as an evaluation of the risk of suicide are measured before and after treatment. Whether psychiatric aftercare has been scheduled for inpatients and the rate of rehospitalization are also registered. Descriptive data: The database was launched in 2011. Every year since then ~5,500 inpatients and 7,500 outpatients have been registered annually in the database. A total of 24,083 inpatients and 29,918 outpatients have been registered. The DDD produces an annual report published on the Internet. Conclusion: The DDD can become an important tool for quality improvement and research, when the reporting is more complete. Keywords: quality assurance, suicide, somatic diseases, national database

  15. Use of the Medicare database in epidemiologic and health services research: a valuable source of real-world evidence on the older and disabled populations in the US

    Directory of Open Access Journals (Sweden)

    Mues KE

    2017-05-01

    Full Text Available Katherine E Mues,1 Alexander Liede,1 Jiannong Liu,2 James B Wetmore,2 Rebecca Zaha,1 Brian D Bradbury,1 Allan J Collins,2 David T Gilbertson2 1Center for Observational Research, Amgen Inc., Thousand Oaks and San Francisco, CA, 2Chronic Disease Research Group, Minneapolis, MN, USA Abstract: Medicare is the federal health insurance program for individuals in the US who are aged ≥65 years, select individuals with disabilities aged <65 years, and individuals with end-stage renal disease. The Centers for Medicare and Medicaid Services grants researchers access to Medicare administrative claims databases for epidemiologic and health outcomes research. The data cover beneficiaries’ encounters with the health care system and receipt of therapeutic interventions, including medications, procedures, and services. Medicare data have been used to describe patterns of morbidity and mortality, describe burden of disease, compare effectiveness of pharmacologic therapies, examine cost of care, evaluate the effects of provider practices on the delivery of care and patient outcomes, and explore the health impacts of important Medicare policy changes. Considering that the vast majority of US citizens ≥65 years of age have Medicare insurance, analyses of Medicare data are now essential for understanding the provision of health care among older individuals in the US and are critical for providing real-world evidence to guide decision makers. This review is designed to provide researchers with a summary of Medicare data, including the types of data that are captured, and how they may be used in epidemiologic and health outcomes research. We highlight strengths, limitations, and key considerations when designing a study using Medicare data. Additionally, we illustrate the potential impact that Centers for Medicare and Medicaid Services policy changes may have on data collection, coding, and ultimately on findings derived from the data. Keywords: Medicare

  16. Giving raw data a chance to talk: a demonstration of exploratory visual analytics with a pediatric research database using Microsoft Live Labs Pivot to promote cohort discovery, research, and quality assessment.

    Science.gov (United States)

    Viangteeravat, Teeradache; Nagisetty, Naga Satya V Rao

    2014-01-01

    Secondary use of large and open data sets provides researchers with an opportunity to address high-impact questions that would otherwise be prohibitively expensive and time consuming to study. Despite the availability of data, generating hypotheses from huge data sets is often challenging, and the lack of complex analysis of data might lead to weak hypotheses. To overcome these issues and to assist researchers in building hypotheses from raw data, we are working on a visual and analytical platform called PRD Pivot. PRD Pivot is a de-identified pediatric research database designed to make secondary use of rich data sources, such as the electronic health record (EHR). The development of visual analytics using Microsoft Live Labs Pivot makes the process of data elaboration, information gathering, knowledge generation, and complex information exploration transparent to tool users and provides researchers with the ability to sort and filter by various criteria, which can lead to strong, novel hypotheses.

  17. 网络微博中公共领域与私人领域的融合%The Fusion of the Public Domain and Private Sphere in Network Micro Blog

    Institute of Scientific and Technical Information of China (English)

    石良

    2012-01-01

    It is clarified that based on the public domain and the private sphere,the paper chooses the micro blog as a starting point,takes examples from sociological theory such as discursive power,social role,and opinion leaders,the fusion tendency of the public domain-private sector in the network——the public domain personal and private sector public is clarified.And it is analyzed that based on reality,the effect is brought to the society by fusion of the public or private field.%把微博作为切入点,借鉴话语权、社会角色、意见领袖等社会学理论阐释了网络中公共领域和私人领域融合的趋势——公共领域私人化与私人领域公共化。并且立足现实,分析了公私领域融合给社会带来的现实影响。

  18. Epilepsy informatics and an ontology-driven infrastructure for large database research and patient care in epilepsy

    Science.gov (United States)

    Sahoo, Satya S.; Zhang, Guo-Qiang; Lhatoo, Samden D.

    2013-01-01

    Summary The epilepsy community increasingly recognizes the need for a modern classification system that can also be easily integrated with effective informatics tools. The 2010 reports by the United States President's Council of Advisors on Science and Technology (PCAST) identified informatics as a critical resource to improve quality of patient care, drive clinical research, and reduce the cost of health services. An effective informatics infrastructure for epilepsy, which is underpinned by a formal knowledge model or ontology, can leverage an ever increasing amount of multimodal data to improve (1) clinical decision support, (2) access to information for patients and their families, (3) easier data sharing, and (4) accelerate secondary use of clinical data. Modeling the recommendations of the International League Against Epilepsy (ILAE) classification system in the form of an epilepsy domain ontology is essential for consistent use of terminology in a variety of applications, including electronic health records systems and clinical applications. In this review, we discuss the data management issues in epilepsy and explore the benefits of an ontology-driven informatics infrastructure and its role in adoption of a “data-driven” paradigm in epilepsy research. PMID:23647220

  19. Scientific publications and research groups on alcohol consumption and related problems worldwide: authorship analysis of papers indexed in PubMed and Scopus databases (2005 to 2009).

    Science.gov (United States)

    González-Alcaide, Gregorio; Castelló-Cogollos, Lourdes; Castellano-Gómez, Miguel; Agullo-Calatayud, Víctor; Aleixandre-Benavent, Rafael; Alvarez, Francisco Javier; Valderrama-Zurián, Juan Carlos

    2013-01-01

    The research of alcohol consumption-related problems is a multidisciplinary field. The aim of this study is to analyze the worldwide scientific production in the area of alcohol-drinking and alcohol-related problems from 2005 to 2009. A MEDLINE and Scopus search on alcohol (alcohol-drinking and alcohol-related problems) published from 2005 to 2009 was carried out. Using bibliometric indicators, the distribution of the publications was determined within the journals that publish said articles, specialty of the journal (broad subject terms), article type, language of the publication, and country where the journal is published. Also, authorship characteristics were assessed (collaboration index and number of authors who have published more than 9 documents). The existing research groups were also determined. About 24,100 documents on alcohol, published in 3,862 journals, and authored by 69,640 authors were retrieved from MEDLINE and Scopus between the years 2005 and 2009. The collaboration index of the articles was 4.83 ± 3.7. The number of consolidated research groups in the field was identified as 383, with 1,933 authors. Documents on alcohol were published mainly in journals covering the field of "Substance-Related Disorders," 23.18%, followed by "Medicine," 8.7%, "Psychiatry," 6.17%, and "Gastroenterology," 5.25%. Research on alcohol is a consolidated field, with an average of 4,820 documents published each year between 2005 and 2009 in MEDLINE and Scopus. Alcohol-related publications have a marked multidisciplinary nature. Collaboration was common among alcohol researchers. There is an underrepresentation of alcohol-related publications in languages other than English and from developing countries, in MEDLINE and Scopus databases. Copyright © 2012 by the Research Society on Alcoholism.

  20. ASIAN AGRICULTURAL RESEARCH is indexed by CABI,CSA Illumina,AGE and other famous databases,famous research institutes and teaching organizations of many countries

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>Through the joint efforts of personnel in editorial office and multitudinous readers, ASIAN AGRICULTURAL RESEARCH eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as

  1. ASIAN AGRICULTURAL RESEARCH is indexed by CABI,CSA Illumina,AGE and other famous databases,famous research institutes and teaching organizations of many countries

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>Through the joint efforts of personnel in editorial office and multitudinous readers, ASIAN AGRICULTURAL RESEARCH eventually passes the extremely strid appraisal, to be indexed by CABI’s full text repository.

  2. Database Description - RED | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available icroarray Project and other research groups. Features and manner of utilization o...f database If you are interested in a particular research subject, can find the appropriate Research ID from... the red_subject_info table. You will then get the experimental data for the selected research. Also, you ca

  3. Evaluation of Scientific Outputs of Kashan University of Medical Sciences in Scopus Citation Database based on Scopus, ResearchGate, and Mendeley Scientometric Measures.

    Science.gov (United States)

    Batooli, Zahra; Ravandi, Somaye Nadi; Bidgoli, Mohammad Sabahi

    2016-02-01

    It is essential to evaluate the impact of scientific publications through citation analysis in citation indexes. In addition, scientometric measures of social media also should be assessed. These measures include how many times the publications were read, viewed, and downloaded. The present study aimed to assess the scientific output of scholars at Kashan University of Medical Sciences by the end of March 2014 based on scientometric measures of Scopus, ResearchGate, and Mendeley. A survey method was used to study the articles published in Scopus journals by scholars at Kashan University of Medical Sciences by the end of March 2014. The required data were collected from Scopus, ResearchGate, and Mendeley. The data were analyzed with descriptive statistics. Also, the Spearman correlation was used between the number of views of articles in ResearchGate with citation number of the articles in Scopus and reading frequency of the articles in Mendeley with citation number in Scopus were examined using the Spearman correlation in SPSS 16. Five-hundred and thirty-three articles were indexed in the Scopus Citation Database by the end of March 2014. Collectively, those articles were cited 1,315 times. The articles were covered by ResearchGate (74%) more than Mendeley (44%). In addition, 98% of the articles indexed in ResearchGate and 92% of the articles indexed in Mendeley were viewed at least once. The results showed that there was a positive correlation between the number of views of the articles in ResearchGate and Mendeley and the number of citations of the articles in Scopus. Coverage and the number of visitors were higher in ResearchGate than in Mendeley. The increase in the number of views of articles in ResearchGate and Mendeley also increased the number of citations of the papers. Social networks, such as ResearchGate and Mendeley, also can be used as tools for the evaluation of academics and scholars based on the scientific research they have conducted.

  4. Fiscal 1996 report on the investigational research on the construction of a database of physical functions; 1996 nendo chosa hokokusho (shintai kino database no kochiku ni kansuru chosa kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    For the purpose of realizing `the affluence` sought in the Japanese economic society, the supply and preparation of products, service and environments friendly to human beings seem to be important. In the future, the development of products which are fully considered also of aged and handicapped people is more expected than the conventional manufacturing of products added with value. Especially in accordance with the rapid aging, from a viewpoint that the lowering of physical functions caused by aging has an exactly close relation with the response to products and the environment, development of the database of physical functions for the aged which is useful for the design is urgently promoted. First, the data to be supplied for database were selected. As to the selection method, the data required for database were defined by collection/analysis of the existing data, examination of the needs of enterprise designers, and analysis of daily activities. In the study of the database, the structure by which data can be effectively supplied was studied and verified by pilot database for extraction of the subjects and solution to the problems. 6 refs., 57 figs., 26 tabs.

  5. Mouse genome database 2016.

    Science.gov (United States)

    Bult, Carol J; Eppig, Janan T; Blake, Judith A; Kadin, James A; Richardson, Joel E

    2016-01-01

    The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data.

  6. Database Description - Q-TARO | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available tiva Taxonomy ID: 4530 Database description This is a database of Rice QTL information extracted from published research...pare their positions. To facilitate reliable comparisons of rice QTLs, we extracted QTL information from published research

  7. A Database of Invariant Rings

    OpenAIRE

    Kemper, Gregor; Körding, Elmar; Malle, Gunter; Matzat, B. Heinrich; Vogel, Denis; Wiese, Gabor

    2001-01-01

    We announce the creation of a database of invariant rings. This database contains a large number of invariant rings of finite groups, mostly in the modular case. It gives information on generators and structural properties of the invariant rings. The main purpose is to provide a tool for researchers in invariant theory.

  8. Semantic web services for web databases

    CERN Document Server

    Ouzzani, Mourad

    2011-01-01

    Semantic Web Services for Web Databases introduces an end-to-end framework for querying Web databases using novel Web service querying techniques. This includes a detailed framework for the query infrastructure for Web databases and services. Case studies are covered in the last section of this book. Semantic Web Services For Web Databases is designed for practitioners and researchers focused on service-oriented computing and Web databases.

  9. ASIAN AGRICULTURAL RESEARCH is indexed by CABI,CSA Illumina,AGE and other famous databases,famous research institutes and teaching organizations of many countries

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>Through the joint efforts of personnel in editorial office and multitudinous readers, ASIAN AGRICULTURAL RESEARCH eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most authoritative and

  10. 汽车覆盖件模具切削物理数据库研究%Research on Physical Database of Automobile Panel Die Cutting

    Institute of Scientific and Technical Information of China (English)

    吴雪峰; 冯高成

    2016-01-01

    近年来我国汽车制造业的迅速发展,导致汽车覆盖件模具需求很大.目前,很多发达国家学者进行了金属切削数据库的开发和研究,然而我国针对于汽车覆盖件模具切削加工的先进切削数据库系统比较少.本文以汽车覆盖件模具切削为研究对象,通过研究模具加工中的基础切削问题与基本加工工艺,以服务的角度出发,采用大数据、云计算技术建立汽车用淬硬钢模具切削基础数据库云平台,挖掘机床性能、加工工艺、刀具选择与加工质量的基本关系,提供标准模具工艺查询、工艺参数优化、刀具优选等服务,为智能机床装备的使用提供基础数据支持.%In recent years,the rapid development of Chinese automobile manufacturing industry causes great needs of automobile cover die. At present,many developed country scholars have conducted the research and development of metal cutting database,however,there are less advanced die machining cutting database sys-tem for automobile panel die cutting in our country. Aiming at automobile panel die cutting,automotive hard-ened die steel cutting cloud database platform is established through the study of basic cutting problem and the basic processing technology of die processing by big data and cloud computing technology. According to the service starting,the basic relationship between the performance of the machine tool is studied,and machining process and tool selection with processing quality,services of standard die technology query and optimization of process parameters and tool selection are provided to offer basic data support for the use of intelligent machine tool equipment.

  11. Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice Research Database.

    Science.gov (United States)

    Mackenzie, I S; Morant, S V; Bloomfield, G A; MacDonald, T M; O'Riordan, J

    2014-01-01

    To estimate the incidence and prevalence of multiple sclerosis (MS) by age and describe secular trends and geographic variations within the UK over the 20-year period between 1990 and 2010 and hence to provide updated information on the impact of MS throughout the UK. A descriptive study. The study was carried out in the General Practice Research Database (GPRD), a primary care database representative of the UK population. Incidence and prevalence of MS per 100 000 population. Secular and geographical trends in incidence and prevalence of MS. The prevalence of MS recorded in GPRD increased by about 2.4% per year (95% CI 2.3% to 2.6%) reaching 285.8 per 100 000 in women (95% CI 278.7 to 293.1) and 113.1 per 100 000 in men (95% CI 108.6 to 117.7) by 2010. There was a consistent downward trend in incidence of MS reaching 11.52 per 100 000/year (95% CI 10.96 to 12.11) in women and 4.84 per 100 000/year (95% CI 4.54 to 5.16) in men by 2010. Peak incidence occurred between ages 40 and 50 years and maximum prevalence between ages 55 and 60 years. Women accounted for 72% of prevalent and 71% of incident cases. Scotland had the highest incidence and prevalence rates in the UK. We estimate that 126 669 people were living with MS in the UK in 2010 (203.4 per 100 000 population) and that 6003 new cases were diagnosed that year (9.64 per 100 000/year). There is an increasing population living longer with MS, which has important implications for resource allocation for MS in the UK.

  12. The Definition of a Prolonged Intensive Care Unit Stay for Spontaneous Intracerebral Hemorrhage Patients: An Application with National Health Insurance Research Database

    Directory of Open Access Journals (Sweden)

    Chien-Lung Chan

    2014-01-01

    Full Text Available Introduction. Length of stay (LOS in the intensive care unit (ICU of spontaneous intracerebral hemorrhage (sICH patients is one of the most important issues. The disease severity, psychosocial factors, and institutional factors will influence the length of ICU stay. This study is used in the Taiwan National Health Insurance Research Database (NHIRD to define the threshold of a prolonged ICU stay in sICH patients. Methods. This research collected the demographic data of sICH patients in the NHIRD from 2005 to 2009. The threshold of prolonged ICU stay was calculated using change point analysis. Results. There were 1599 sICH patients included. A prolonged ICU stay was defined as being equal to or longer than 10 days. There were 436 prolonged ICU stay cases and 1163 nonprolonged cases. Conclusion. This study showed that the threshold of a prolonged ICU stay is a good indicator of hospital utilization in ICH patients. Different hospitals have their own different care strategies that can be identified with a prolonged ICU stay. This indicator can be improved using quality control methods such as complications prevention and efficiency of ICU bed management. Patients’ stay in ICUs and in hospitals will be shorter if integrated care systems are established.

  13. Tidal Creek Sentinel Habitat Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Ecological Research, Assessment and Prediction's Tidal Creeks: Sentinel Habitat Database was developed to support the National Oceanic and Atmospheric...

  14. DATABASE REPLICATION IN HETEROGENOUS PLATFORM

    Directory of Open Access Journals (Sweden)

    Hendro Nindito

    2014-01-01

    Full Text Available The application of diverse database technologies in enterprises today is increasingly a common practice. To provide high availability and survavibality of real-time information, a database replication technology that has capability to replicate databases under heterogenous platforms is required. The purpose of this research is to find the technology with such capability. In this research, the data source is stored in MSSQL database server running on Windows. The data will be replicated to MySQL running on Linux as the destination. The method applied in this research is prototyping in which the processes of development and testing can be done interactively and repeatedly. The key result of this research is that the replication technology applied, which is called Oracle GoldenGate, can successfully manage to do its task in replicating data in real-time and heterogeneous platforms.

  15. International Ventilation Cooling Application Database

    DEFF Research Database (Denmark)

    Holzer, Peter; Psomas, Theofanis Ch.; OSullivan, Paul

    2016-01-01

    The currently running International Energy Agency, Energy and Conservation in Buildings, Annex 62 Ventilative Cooling (VC) project, is coordinating research towards extended use of VC. Within this Annex 62 the joint research activity of International VC Application Database has been carried out...... European and international Low Energy buildings. Still it’s not really widespread. Obstacles are challenges as regards noise, dust, weather and burglary, proving the research efforts of the Annex being necessary. The VC database forms a worthwhile basis for both dissemination and further research targets......., systematically investigating the distribution of technologies and strategies within VC. The database is structured as both a ticking-list-like building-spreadsheet and a collection of building-datasheets. The content of both closely follows Annex 62 State-Of-The- Art-Report. The database has been filled, based...

  16. Free access to INIS database provides a gateway to nuclear energy research results; INIS-tietokanta avaa paeaesyn ydinenergia-alan tutkimustuloksiin

    Energy Technology Data Exchange (ETDEWEB)

    Tolonen, E.; Malmgren, M. (Aalto Univ., Espoo (Finland). e-mail:eva.tolonen@tkk.fi; marja.malmgren@tkk.fi)

    2009-07-01

    Free access to INIS database was opened to all the Internet users around the world on May, 2009. The article reviews the history of INIS (the International Nuclear Information System), data aquisition process, database content and search possibilities. INIS is focused on the worldwide literature of the peaceful uses of nuclear energy and the database is produced in close collaboration with the IEA/ETDE World Energy Base (ETDEWEB), a database focusing on all aspects of energy. Nuclear Science Abstracts database (NSA), which is a comprehensive collection of international nuclear science and technology literature for the period 1948 through 1976, is also briefly discussed in the article. In Finland, the recently formed Aalto University is responsible for collecting and disseminating information (literature) and for the preparation of input to the INIS and IEA/ETDE Databases on the national level

  17. The NIDDK Information Network: A Community Portal for Finding Data, Materials, and Tools for Researchers Studying Diabetes, Digestive, and Kidney Diseases.

    Directory of Open Access Journals (Sweden)

    Patricia L Whetzel

    Full Text Available The NIDDK Information Network (dkNET; http://dknet.org was launched to serve the needs of basic and clinical investigators in metabolic, digestive and kidney disease by facilitating access to research resources that advance the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK. By research resources, we mean the multitude of data, software tools, materials, services, projects and organizations available to researchers in the public domain. Most of these are accessed via web-accessible databases or web portals, each developed, designed and maintained by numerous different projects, organizations and individuals. While many of the large government funded databases, maintained by agencies such as European Bioinformatics Institute and the National Center for Biotechnology Information, are well known to researchers, many more that have been developed by and for the biomedical research community are unknown or underutilized. At least part of the problem is the nature of dynamic databases, which are considered part of the "hidden" web, that is, content that is not easily accessed by search engines. dkNET was created specifically to address the challenge of connecting researchers to research resources via these types of community databases and web portals. dkNET functions as a "search engine for data", searching across millions of database records contained in hundreds of biomedical databases developed and maintained by independent projects around the world. A primary focus of dkNET are centers and projects specifically created to provide high quality data and resources to NIDDK researchers. Through the novel data ingest process used in dkNET, additional data sources can easily be incorporated, allowing it to scale with the growth of digital data and the needs of the dkNET community. Here, we provide an overview of the dkNET portal and its functions. We show how dkNET can be used to address a variety of use cases

  18. The NIDDK Information Network: A Community Portal for Finding Data, Materials, and Tools for Researchers Studying Diabetes, Digestive, and Kidney Diseases

    Science.gov (United States)

    Whetzel, Patricia L.; Grethe, Jeffrey S.; Banks, Davis E.; Martone, Maryann E.

    2015-01-01

    The NIDDK Information Network (dkNET; http://dknet.org) was launched to serve the needs of basic and clinical investigators in metabolic, digestive and kidney disease by facilitating access to research resources that advance the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). By research resources, we mean the multitude of data, software tools, materials, services, projects and organizations available to researchers in the public domain. Most of these are accessed via web-accessible databases or web portals, each developed, designed and maintained by numerous different projects, organizations and individuals. While many of the large government funded databases, maintained by agencies such as European Bioinformatics Institute and the National Center for Biotechnology Information, are well known to researchers, many more that have been developed by and for the biomedical research community are unknown or underutilized. At least part of the problem is the nature of dynamic databases, which are considered part of the “hidden” web, that is, content that is not easily accessed by search engines. dkNET was created specifically to address the challenge of connecting researchers to research resources via these types of community databases and web portals. dkNET functions as a “search engine for data”, searching across millions of database records contained in hundreds of biomedical databases developed and maintained by independent projects around the world. A primary focus of dkNET are centers and projects specifically created to provide high quality data and resources to NIDDK researchers. Through the novel data ingest process used in dkNET, additional data sources can easily be incorporated, allowing it to scale with the growth of digital data and the needs of the dkNET community. Here, we provide an overview of the dkNET portal and its functions. We show how dkNET can be used to address a variety of use cases that involve

  19. The AMMA database

    Science.gov (United States)

    Boichard, Jean-Luc; Brissebrat, Guillaume; Cloche, Sophie; Eymard, Laurence; Fleury, Laurence; Mastrorillo, Laurence; Moulaye, Oumarou; Ramage, Karim

    2010-05-01

    The AMMA project includes aircraft, ground-based and ocean measurements, an intensive use of satellite data and diverse modelling studies. Therefore, the AMMA database aims at storing a great amount and a large variety of data, and at providing the data as rapidly and safely as possible to the AMMA research community. In order to stimulate the exchange of information and collaboration between researchers from different disciplines or using different tools, the database provides a detailed description of the products and uses standardized formats. The AMMA database contains: - AMMA field campaigns datasets; - historical data in West Africa from 1850 (operational networks and previous scientific programs); - satellite products from past and future satellites, (re-)mapped on a regular latitude/longitude grid and stored in NetCDF format (CF Convention); - model outputs from atmosphere or ocean operational (re-)analysis and forecasts, and from research simulations. The outputs are processed as the satellite products are. Before accessing the data, any user has to sign the AMMA data and publication policy. This chart only covers the use of data in the framework of scientific objectives and categorically excludes the redistribution of data to third parties and the usage for commercial applications. Some collaboration between data producers and users, and the mention of the AMMA project in any publication is also required. The AMMA database and the associated on-line tools have been fully developed and are managed by two teams in France (IPSL Database Centre, Paris and OMP, Toulouse). Users can access data of both data centres using an unique web portal. This website is composed of different modules : - Registration: forms to register, read and sign the data use chart when an user visits for the first time - Data access interface: friendly tool allowing to build a data extraction request by selecting various criteria like location, time, parameters... The request can

  20. The Danish Sarcoma Database

    Directory of Open Access Journals (Sweden)

    Jorgensen PH

    2016-10-01

    complications, and recurrence within 5 years follow-up. The database is also a valuable research tool to study the impact of technical and medical interventions on prognosis of sarcoma patients. Keywords: sarcoma, skeletal and ekstraskeletal, population-based database, online database, quality indicators

  1. MetaBase—the wiki-database of biological databases

    Science.gov (United States)

    Bolser, Dan M.; Chibon, Pierre-Yves; Palopoli, Nicolas; Gong, Sungsam; Jacob, Daniel; Angel, Victoria Dominguez Del; Swan, Dan; Bassi, Sebastian; González, Virginia; Suravajhala, Prashanth; Hwang, Seungwoo; Romano, Paolo; Edwards, Rob; Bishop, Bryan; Eargle, John; Shtatland, Timur; Provart, Nicholas J.; Clements, Dave; Renfro, Daniel P.; Bhak, Daeui; Bhak, Jong

    2012-01-01

    Biology is generating more data than ever. As a result, there is an ever increasing number of publicly available databases that analyse, integrate and summarize the available data, providing an invaluable resource for the biological community. As this trend continues, there is a pressing need to organize, catalogue and rate these resources, so that the information they contain can be most effectively exploited. MetaBase (MB) (http://MetaDatabase.Org) is a community-curated database containing more than 2000 commonly used biological databases. Each entry is structured using templates and can carry various user comments and annotations. Entries can be searched, listed, browsed or queried. The database was created using the same MediaWiki technology that powers Wikipedia, allowing users to contribute on many different levels. The initial release of MB was derived from the content of the 2007 Nucleic Acids Research (NAR) Database Issue. Since then, approximately 100 databases have been manually collected from the literature, and users have added information for over 240 databases. MB is synchronized annually with the static Molecular Biology Database Collection provided by NAR. To date, there have been 19 significant contributors to the project; each one is listed as an author here to highlight the community aspect of the project. PMID:22139927

  2. The Danish Testicular Cancer database

    Directory of Open Access Journals (Sweden)

    Daugaard G

    2016-10-01

    Full Text Available Gedske Daugaard,1 Maria Gry Gundgaard Kier,1 Mikkel Bandak,1 Mette Saksø Mortensen,1 Heidi Larsson,2 Mette Søgaard,2 Birgitte Groenkaer Toft,3 Birte Engvad,4 Mads Agerbæk,5 Niels Vilstrup Holm,6 Jakob Lauritsen1 1Department of Oncology 5073, Copenhagen University Hospital, Rigshospitalet, Copenhagen, 2Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, 3Department of Pathology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, 4Department of Pathology, Odense University Hospital, Odense, 5Department of Oncology, Aarhus University Hospital, Aarhus, 6Department of Oncology, Odense University Hospital, Odense, Denmark Aim: The nationwide Danish Testicular Cancer database consists of a retrospective research database (DaTeCa database and a prospective clinical database (Danish Multidisciplinary Cancer Group [DMCG] DaTeCa database. The aim is to improve the quality of care for patients with testicular cancer (TC in Denmark, that is, by identifying risk factors for relapse, toxicity related to treatment, and focusing on late effects. Study population: All Danish male patients with a histologically verified germ cell cancer diagnosis in the Danish Pathology Registry are included in the DaTeCa databases. Data collection has been performed from 1984 to 2007 and from 2013 onward, respectively. Main variables and descriptive data: The retrospective DaTeCa database contains detailed information with more than 300 variables related to histology, stage, treatment, relapses, pathology, tumor markers, kidney function, lung function, etc. A questionnaire related to late effects has been conducted, which includes questions regarding social relationships, life situation, general health status, family background, diseases, symptoms, use of medication, marital status, psychosocial issues, fertility, and sexuality. TC survivors alive on October 2014 were invited to fill in this questionnaire including 160 validated questions

  3. Database on wind characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, K.S. [The Technical Univ. of Denmark (Denmark); Courtney, M.S. [Risoe National Lab., (Denmark)

    1999-08-01

    The organisations that participated in the project consists of five research organisations: MIUU (Sweden), ECN (The Netherlands), CRES (Greece), DTU (Denmark), Risoe (Denmark) and one wind turbine manufacturer: Vestas Wind System A/S (Denmark). The overall goal was to build a database consisting of a large number of wind speed time series and create tools for efficiently searching through the data to select interesting data. The project resulted in a database located at DTU, Denmark with online access through the Internet. The database contains more than 50.000 hours of measured wind speed measurements. A wide range of wind climates and terrain types are represented with significant amounts of time series. Data have been chosen selectively with a deliberate over-representation of high wind and complex terrain cases. This makes the database ideal for wind turbine design needs but completely unsuitable for resource studies. Diversity has also been an important aim and this is realised with data from a large range of terrain types; everything from offshore to mountain, from Norway to Greece. (EHS)

  4. Data integration for European marine biodiversity research: creating a database on benthos and plankton to study large-scale patterns and long-term changes

    NARCIS (Netherlands)

    Vandepitte, L.; Vanhoorne, B.; Kraberg, A.; Craeymeersch, J.A.M.

    2010-01-01

    The general aim of setting up a central database on benthos and plankton was to integrate long-, medium- and short-term datasets on marine biodiversity. Such a database makes it possible to analyse species assemblages and their changes on spatial and temporal scales across Europe. Data collation las

  5. Data integration for European marine biodiversity research: creating a database on benthos and plankton to study large-scale patterns and long-term changes

    NARCIS (Netherlands)

    Vandepitte, L.; Vanhoorne, B.; Kraberg, A.; Anisimova, N.; Antoniadou, C.; Araújo, R.; Bartsch, I.; Beker, B.; Benedetti-Cecchi, L.; Bertocci, I.; Cochrane, S.J.; Cooper, K.; Craeymeersch, J.A.; Christou, E.; Crisp, D.J.; Dahle, S.; de Boissier, M.; De Kluijver, M.; Denisenko, S.; De Vito, D.; Duineveld, G.; Escaravage, V.L.; Fleischer, D.; Fraschetti, S.; Giangrande, A.; Heip, C.H.R.; Hummel, H.; Janas, U.; Karez, R.; Kedra, M.; Kingston, P.; Kuhlenkamp, R.; Libes, M.; Martens, P.; Mees, J.; Mieszkowska, N.; Mudrak, S.; Munda, I.; Orfanidis, S.; Orlando-Bonaca, M.; Palerud, R.; Rachor, E.; Reichert, K.; Rumohr, H.; Schiedek, D.; Schubert, P.; Sistermans, W.C.H.; Sousa Pinto, I.S.; Southward, A.J.; Terlizzi, A.; Tsiaga, E.; Van Beusekom, J.E.E.; Vanden Berghe, E.; Warzocha, J.; Wasmund, N.; Weslawski, J.M.; Widdicombe, C.; Wlodarska-Kowalczuk, M.; Zettler, M.L.

    2010-01-01

    The general aim of setting up a central database on benthos and plankton was to integrate long-, medium- and short-term datasets on marine biodiversity. Such a database makes it possible to analyse species assemblages and their changes on spatial and temporal scales across Europe. Data collation

  6. The Arabidopsis Information Resource (TAIR): a model organism database providing a centralized, curated gateway to Arabidopsis biology, research materials and community.

    Science.gov (United States)

    Rhee, Seung Yon; Beavis, William; Berardini, Tanya Z; Chen, Guanghong; Dixon, David; Doyle, Aisling; Garcia-Hernandez, Margarita; Huala, Eva; Lander, Gabriel; Montoya, Mary; Miller, Neil; Mueller, Lukas A; Mundodi, Suparna; Reiser, Leonore; Tacklind, Julie; Weems, Dan C; Wu, Yihe; Xu, Iris; Yoo, Daniel; Yoon, Jungwon; Zhang, Peifen

    2003-01-01

    Arabidopsis thaliana is the most widely-studied plant today. The concerted efforts of over 11 000 researchers and 4000 organizations around the world are generating a rich diversity and quantity of information and materials. This information is made available through a comprehensive on-line resource called the Arabidopsis Information Resource (TAIR) (http://arabidopsis.org), which is accessible via commonly used web browsers and can be searched and downloaded in a number of ways. In the last two years, efforts have been focused on increasing data content and diversity, functionally annotating genes and gene products with controlled vocabularies, and improving data retrieval, analysis and visualization tools. New information include sequence polymorphisms including alleles, germplasms and phenotypes, Gene Ontology annotations, gene families, protein information, metabolic pathways, gene expression data from microarray experiments and seed and DNA stocks. New data visualization and analysis tools include SeqViewer, which interactively displays the genome from the whole chromosome down to 10 kb of nucleotide sequence and AraCyc, a metabolic pathway database and map tool that allows overlaying expression data onto the pathway diagrams. Finally, we have recently incorporated seed and DNA stock information from the Arabidopsis Biological Resource Center (ABRC) and implemented a shopping-cart style on-line ordering system.

  7. Study on Establishment and Research of a National Costumes Database System%民族服饰数据库系统的建立与研究

    Institute of Scientific and Technical Information of China (English)

    郭敏

    2015-01-01

    从民族服饰文化的现状入手,研究了民族服饰数据库系统的总体设计、系统实现的关键技术、主要功能模块的设计,并挖掘出其长远的应用前景. 此系统的建立,弘扬了民族服饰文化,使得民族服饰文化遗产得到了很好的保存.%Starting from the current situation of national costumes culture ,it researched the overall design of national costumes database system ,the key techniques of system implementation ,the design of the main functional modules in this paper ,and dug the system′s long-term application prospect .The establishment of this system which carries forward the national costume culture ,making the national dress culture herit-age is well preserved .

  8. 数据库加密技术的研究与应用%Research and Application of Database Encryption Technology

    Institute of Scientific and Technical Information of China (English)

    韩利凯

    2011-01-01

    数据库加密技术是实现数据库信息安全的一种有效方法.从数据库系统的安全需求着手,对数据库加密的基本要求、数据库加密技术中的关键问题等进行了研究和探讨,提出了数据库加密技术在B/S学籍管理系统中的实现方案.%Database encryption technology is an effective method for realizing database information security.This article studies and discusses the basic requirements of database encryption and the key problems in database encryption technology.It also puts forward a scheme of applying database encryption technology in B/S registration management system.

  9. Database development and management

    CERN Document Server

    Chao, Lee

    2006-01-01

    Introduction to Database Systems Functions of a DatabaseDatabase Management SystemDatabase ComponentsDatabase Development ProcessConceptual Design and Data Modeling Introduction to Database Design Process Understanding Business ProcessEntity-Relationship Data Model Representing Business Process with Entity-RelationshipModelTable Structure and NormalizationIntroduction to TablesTable NormalizationTransforming Data Models to Relational Databases .DBMS Selection Transforming Data Models to Relational DatabasesEnforcing ConstraintsCreating Database for Business ProcessPhysical Design and Database

  10. The Danish Melanoma Database

    Directory of Open Access Journals (Sweden)

    Hölmich Lr

    2016-10-01

    Full Text Available Lisbet Rosenkrantz Hölmich,1 Siri Klausen,2 Eva Spaun,3 Grethe Schmidt,4 Dorte Gad,5 Inge Marie Svane,6,7 Henrik Schmidt,8 Henrik Frank Lorentzen,9 Else Helene Ibfelt10 1Department of Plastic Surgery, 2Department of Pathology, Herlev-Gentofte Hospital, University of Copenhagen, Herlev, 3Institute of Pathology, Aarhus University Hospital, Aarhus, 4Department of Plastic and Reconstructive Surgery, Breast Surgery and Burns, Rigshospitalet – Glostrup, University of Copenhagen, Copenhagen, 5Department of Plastic Surgery, Odense University Hospital, Odense, 6Center for Cancer Immune Therapy, Department of Hematology, 7Department of Oncology, Herlev-Gentofte Hospital, University of Copenhagen, Herlev, 8Department of Oncology, 9Department of Dermatology, Aarhus University Hospital, Aarhus, 10Registry Support Centre (East – Epidemiology and Biostatistics, Research Centre for Prevention and Health, Glostrup – Rigshospitalet, University of Copenhagen, Glostrup, Denmark Aim of database: The aim of the database is to monitor and improve the treatment and survival of melanoma patients.Study population: All Danish patients with cutaneous melanoma and in situ melanomas must be registered in the Danish Melanoma Database (DMD. In 2014, 2,525 patients with invasive melanoma and 780 with in situ tumors were registered. The coverage is currently 93% compared with the Danish Pathology Register.Main variables: The main variables include demographic, clinical, and pathological characteristics, including Breslow’s tumor thickness, ± ulceration, mitoses, and tumor–node–metastasis stage. Information about the date of diagnosis, treatment, type of surgery, including safety margins, results of lymphoscintigraphy in patients for whom this was indicated (tumors > T1a, results of sentinel node biopsy, pathological evaluation hereof, and follow-up information, including recurrence, nature, and treatment hereof is registered. In case of death, the cause and date

  11. 基于空间数据库VRGIS的研究与应用%The Research and Application for VRGIS Based on the Spatial Database

    Institute of Scientific and Technical Information of China (English)

    宋敏; 申闫春

    2012-01-01

    结合空间数据库、GIS、计算机图形学、RS等技术构建了虚拟现实地理信息系统。通过研究地形数据的生成及空间数据库的存储管理,实现了遥感影像的自动配准及无缝拼接;基于四叉树的LOD算法、地形节点评价系统、动态调度及大规模纹理映射等技术的研究,实现了地形数据的3维可视化;提出了自适应特征数据覆盖渲染算法,将2维GIS特征数据覆盖叠加到所创建的3维模型上,构建了虚拟现实环境。该系统成功应用于胜利油田,实现了地下油田的虚拟现实3维可视化,具有一定的理论价值和现实意义。%Combined with the spatial database,GIS,computer graphics,RS technology etc.,the paper constructs VRGIS which has realized the functions of automatic registration and seamless for the remote sensing image through the study of the terrain data generation and spatial database storage management.Additionally it has achieved 3D visualization of the terrain data based on the technology research of quadtree LOD algorithm,terrain node evaluation system,dynamic scheduling and large-scale texture mapping etc.That covers the 2D GIS feature data and adds it to the 3D model and builds the virtual reality environment by using the adaptive feature data cover rendering algorithm.The system has been successfully applied to the project of Shengli oilfield,and has realized the function of virtual reality 3D visualization for the underground oilfield.That has certain theory value and practical significance.

  12. SQL Server数据库DML触发器的研究与应用%Research and Application on DML Trigger of SQL Server Database

    Institute of Scientific and Technical Information of China (English)

    刘维学; 乔丽平

    2013-01-01

    DML触发器是SQL Server数据库中应用最广泛的触发器,在维护数据完整性、提高数据安全性、满足复杂的数据约束等方面具有重要作用。文中对DML触发器的应用进行详细研究。首先,介绍了DML触发器包含的AFTER和IN-STEAD OF两种类型;其次,通过图形表示了AFTER触发器的触发顺序,并阐明了指定触发顺序需要注意的问题;然后,研究INSERT、DELETE、UPDATE三类触发器的工作原理;最后,给出了DML触发器的几个应用技巧。实际运用时要结合文中的研究内容进行详细设计,以便提高数据库系统的整体性能。%DML trigger is the trigger that most widely used in SQL Server database,and plays an important role in maintaining data integ-rity,improving data security,and meeting complex data constraints. Study the application of DML trigger in detail. First,introduce the two types of AFTER and INSTEAD OF that included in DML trigger;Second,show the trigger sequence of AFTER trigger through a graph-ical,and clarify the needing attention problems of specified trigger;Then research the working principle of the three class triggers of IN-SERT,DELETE and UPDATE;Finally,give several application skills of DML trigger. The practical application does the detail design should combine this contents in order to improve the overall performance of database system.

  13. 跨数据库持久层框架的研究与实现%Research and implementation of cross-database persistence layer framework

    Institute of Scientific and Technical Information of China (English)

    李晓龙; 谭景信

    2011-01-01

    SQL方言导致直接在特定数据库上开发的业务系统不能在多种数据库间灵活的迁移,为此提出了一个能够跨数据库的持久层框架.通过建立多数据库开发规范,在持久层框架iBATIS的基础上扩展了对多数据库方言的支持,增加了多数据库SQL解析及数据分页的能力.在二次开发和对SQL执行效率要求高的领域首次解决了系统跨数据库的问题.遵循多数据库开发规范并使用该框架开发的系统就可以实现在多种数据库环境下的无缝迁移.%SQL dialect causes the business systems which develop in the specific database can not flexible migrate between different databases. So a persistence framework is presented, which can support multiple databases. The framework based on Ibatis supports for multiple database dialects by establishing multi-database development of norms. The capacities of multi-database SQL parsing and data paging are added to Ibatis. The problem of cross-database is solved in the requiring high efficiency and secondary development area. The systems which follow the multi-database development of norms and use this framework can seamless migrate in the multiple databases environment.

  14. Towards P2P XML Database Technology

    NARCIS (Netherlands)

    Y. Zhang (Ying)

    2007-01-01

    textabstractTo ease the development of data-intensive P2P applications, we envision a P2P XML Database Management System (P2P XDBMS) that acts as a database middle-ware, providing a uniform database abstraction on top of a dynamic set of distributed data sources. In this PhD work, we research which

  15. Information Literacy Skills: Comparing and Evaluating Databases

    Science.gov (United States)

    Grismore, Brian A.

    2012-01-01

    The purpose of this database comparison is to express the importance of teaching information literacy skills and to apply those skills to commonly used Internet-based research tools. This paper includes a comparison and evaluation of three databases (ProQuest, ERIC, and Google Scholar). It includes strengths and weaknesses of each database based…

  16. Oracle数据库启动过程研究与实践%Research and Operation of Oracle database startup process

    Institute of Scientific and Technical Information of China (English)

    周文琼; 王乐球

    2011-01-01

    On the basis of the analysis Oracle database startup process,described Oracle database startup failure led to different reasons,to simulate a variety of fault,the fault handling process,so that readers better understanding Oracle database startup process.%分析了Oracle数据库启动过程,阐述了导致Oracle数据库启动故障的不同原因,模拟了各种故障,提出了故障的处理过程,使读者对Oracle数据库启动过程有更深入的了解。

  17. ARTI Refrigerant Database

    Energy Technology Data Exchange (ETDEWEB)

    Calm, J.M.

    1992-11-09

    The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air- conditioning and refrigeration equipment. The database identifies sources of specific information on R-32, R-123, R-124, R-125, R-134, R-134a, R-141b, R-142b, R-143a, R-152a, R-245ca, R-290 (propane), R- 717 (ammonia), ethers, and others as well as azeotropic and zeotropic and zeotropic blends of these fluids. It addresses lubricants including alkylbenzene, polyalkylene glycol, ester, and other synthetics as well as mineral oils. It also references documents on compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. A computerized version is available that includes retrieval software.

  18. The DIPPR® databases

    Science.gov (United States)

    Thomson, G. H.

    1996-01-01

    The Design Institute for Physical Property Data® (DIPPR), one of the Sponsored Research groups of the American Institute of Chemical Engineers (AIChE), has been in existence for 15 years and has supported a total of 14 projects, some completed, some ongoing. Four of these projects are “database” projects for which the primary product is a database of carefully evaluated property data. These projects are Data Compilation; Evaluated Data on Mixtures; Environmental, Safety, and Health Data Compilation; and Difusivities and Thermal Properties of Polymer Solutions. This paper lists the existing DIPPR projects; discusses DIPPR's structure and modes of dissemination of results; describes DIPPR's supporters and its unique characteristics; and finally, discusses the origin, nature, and content of the four database projects.

  19. Database systems for knowledge-based discovery.

    Science.gov (United States)

    Jagarlapudi, Sarma A R P; Kishan, K V Radha

    2009-01-01

    Several database systems have been developed to provide valuable information from the bench chemist to biologist, medical practitioner to pharmaceutical scientist in a structured format. The advent of information technology and computational power enhanced the ability to access large volumes of data in the form of a database where one could do compilation, searching, archiving, analysis, and finally knowledge derivation. Although, data are of variable types the tools used for database creation, searching and retrieval are similar. GVK BIO has been developing databases from publicly available scientific literature in specific areas like medicinal chemistry, clinical research, and mechanism-based toxicity so that the structured databases containing vast data could be used in several areas of research. These databases were classified as reference centric or compound centric depending on the way the database systems were designed. Integration of these databases with knowledge derivation tools would enhance the value of these systems toward better drug design and discovery.

  20. La apropiación del dominio público y las posibilidades de acceso a los bienes culturales | The appropriation of the public domain and the possibilities of access to cultural goods

    Directory of Open Access Journals (Sweden)

    Joan Ramos Toledano

    2017-06-01

    Full Text Available Resumen: Las normas de propiedad intelectual y copyright prevén un periodo de protección otorgando unos derechos económicos exclusivos y temporales. Pasado un plazo determinado, las obras protegidas entran en lo que se denomina dominio público. Éste suele ser considerado como el momento en el que los bienes culturales pasan a estar bajo el dominio y control de la sociedad en conjunto. El presente trabajo pretende argumentar que, dado nuestro actual sistema económico, en realidad el dominio público funciona más como una posibilidad de negocio para determinadas empresas que como una verdadera opción para que el público pueda acceder a las obras. Abstract: The legislation of continental intellectual property and copyright provide for a period of protection granting exclusive and temporary economic rights. After a certain period, protected works enter into what is called the public domain. This is often considered as the moment in which the cultural goods come under the control and domain of society as a whole. The present paper pretends to argue that, given our current economic system, the public domain actually functions more as a business opportunity for certain companies than as a real option for the public to access artistic and intellectual works.  

  1. ADO.NET数据访问体系结构研究%Architecture Research of Database Accessing on ADO.NET

    Institute of Scientific and Technical Information of China (English)

    詹发荣

    2009-01-01

    ADO.NET是基于.NET Framework平台下的数据访问技术.该文介绍了ADO.NET的数据访问工作机理,并对ADO.NET和ADO进行了简单比较,分析了ADO.NET框架下访问数据库的两类核心组件,最后给出了采用ADO.NET访问不同数据库需要引入相应的命名空间.%ADO.NET is a technology of database accessing based on .NET Framework, it introduces ADO.NET's database accessing prin-ciple, and it compares ADO.NET and ADO, Analyzing two core module of accessing database under ADO.NET Framework, Finally, ac-cess to different databases using ADO.NET a need to introduce the corresponding namespace.

  2. Research and Design on the Disk Manager of Spatial Database%空间数据库磁盘管理器的研究与设计

    Institute of Scientific and Technical Information of China (English)

    范建伟; 汪林林

    2003-01-01

    The disk manager of spatial database provides uniform storage and management for spatial data and attribute data in GIS applications. To investigate it will have effect on creating storage manager of spatial database and SDBMS with lore's property right for our country. This paper investigates and analyzes the Oracele's spatial data model, and on the basis of it , it puts forward a new method about disk storage of spatial data and has it designed.

  3. A New Database for Speaker Recognition

    DEFF Research Database (Denmark)

    Feng, Ling; Hansen, Lars Kai

    2005-01-01

    In this paper we discuss properties of speech databases used for speaker recognition research and evaluation, and we characterize some popular standard databases. The paper presents a new database called ELSDSR dedicated to speaker recognition applications. The main characteristics of this database...... are: English spoken by non-native speakers, a single session of sentence reading and relatively extensive speech samples suitable for learning person specific speech characteristics....

  4. Risk of Mortality (Including Sudden Cardiac Death and Major Cardiovascular Events in Atypical and Typical Antipsychotic Users: A Study with the General Practice Research Database

    Directory of Open Access Journals (Sweden)

    Tarita Murray-Thomas

    2013-01-01

    Full Text Available Objective. Antipsychotics have been associated with increased cardiac events including mortality. This study assessed cardiac events including mortality among antipsychotic users relative to nonusers. Methods. The General Practice Research Database (GPRD was used to identify antipsychotic users, matched general population controls, and psychiatric diseased nonusers. Outcomes included cardiac mortality, sudden cardiac death (SCD, all-cause mortality (excluding suicide, coronary heart disease (CHD, and ventricular arrhythmias (VA. Sensitivity analyses were conducted for age, dose, duration, antipsychotic type, and psychiatric disease. Results. 183,392 antipsychotic users (115,491 typical and 67,901 atypical, 544,726 general population controls, and 193,920 psychiatric nonusers were identified. Nonusers with schizophrenia, dementia, or bipolar disorder had increased risks of all-cause mortality compared to general population controls, while nonusers with major depression had comparable risks. Relative to psychiatric nonusers, the adjusted relative ratios (aRR of all-cause mortality in antipsychotic users was 1.75 (95% CI: 1.64–1.87; cardiac mortality 1.72 (95% CI: 1.42–2.07; SCD primary definition 5.76 (95% CI: 2.90–11.45; SCD secondary definition 2.15 (95% CI: 1.64–2.81; CHD 1.16 (95% CI: 0.94–1.44; and VA 1.16 (95% CI: 1.02–1.31. aRRs of the various outcomes were lower for atypical versus typical antipsychotics (all-cause mortality 0.83 (95% CI: 0.80–0.85; cardiac mortality 0.89 (95% CI: 0.82–0.97; and SCD secondary definition 0.76 (95% CI: 0.55–1.04. Conclusions. Antipsychotic users had an increased risk of cardiac mortality, all-cause mortality, and SCD compared to a psychiatric nonuser cohort.

  5. Risk of severe acute liver injury among patients with brain cancer treated with temozolomide: a nested case-control study using the healthcore integrated research database.

    Science.gov (United States)

    Desai, Vibha C A; Quinlan, Scott C; Deitz, Anne C; He, Jinghua; Holick, Crystal N; Lanes, Stephan

    2017-08-01

    Temozolomide (TMZ) is used to treat adult patients with glioblastoma multiforme (GBM). Cases of hepatotoxicity have been reported among patients using TMZ. The objective of the study was to assess the relation, if any, between exposure to TMZ and serious acute liver injury (SALI). We used the HealthCore Integrated Research Database to perform a case-control study nested within a retrospective cohort of adult patients aged 18-100 years with at least two diagnoses of brain cancer anytime between 2006 and 2014. Patients without continuous eligibility or with a SALI diagnosis within 6 months prior to the date of incident brain cancer diagnosis were excluded. Medical records were sought for potential SALI cases and reviewed by two hepatologists. Five controls were selected for each case using incidence density sampling, matched on age and calendar year of index date. The analysis included 61 confirmed SALI cases and 305 selected controls. Exposure to TMZ was classified according to dispensing date and days supply of medication dispensed. We estimated odds ratios using conditional logistic regression models. The odds ratio for any exposure to TMZ was 0.91 (95% CI 0.44-1.91), for recent exposure to TMZ was 0.62 (95% CI 0.21-1.85). There was no increased risk of SALI with increasing duration of exposure to TMZ. When patients with unconfirmed SALI were included in the analysis, results were similar (OR 1.04; 95% CI 0.70-1.54). In conclusion, this study did not find an association between TMZ and SALI risk among patients with brain cancer.

  6. OECD/NEA thermochemical database

    Energy Technology Data Exchange (ETDEWEB)

    Byeon, Kee Hoh; Song, Dae Yong; Shin, Hyun Kyoo; Park, Seong Won; Ro, Seung Gy

    1998-03-01

    This state of the art report is to introduce the contents of the Chemical Data-Service, OECD/NEA, and the results of survey by OECD/NEA for the thermodynamic and kinetic database currently in use. It is also to summarize the results of Thermochemical Database Projects of OECD/NEA. This report will be a guide book for the researchers easily to get the validate thermodynamic and kinetic data of all substances from the available OECD/NEA database. (author). 75 refs.

  7. Legacy2Drupal: Conversion of an existing relational oceanographic database to a Drupal 7 CMS

    Science.gov (United States)

    Work, T. T.; Maffei, A. R.; Chandler, C. L.; Groman, R. C.

    2011-12-01

    technologies included in the Drupal 7 core is anticipated. Using a public domain CMS as opposed to proprietary middleware, and taking advantage of the many features of Drupal 7 that are designed to support semantically-enabled interfaces will help prepare the BCO-DMO and other science data repositories for interoperability between systems that serve ecosystem research data.

  8. 基于Delhpi平台的数据库程序设计研究%Research on the Database Programming Based on Delphi Platform

    Institute of Scientific and Technical Information of China (English)

    鲍海燕

    2011-01-01

    数据库技术是当今信息社会的重要基础技术之一,在众多的数据库开发工具当中,Delphi尤为突出,它适应于多种数据库结构,具有高效率的数据库管理系统和最新的数据分析手段并且提供大量的企业组件。介绍了基于Delphi平台的数据库程序设计的原理,各组件功能应用以及数据库的连接方法,通过测试程序对比了各个数据库连接方法的访问时间,得出DBExpress方法优于BDE及ADO,大大提高了Delphi程序设计中数据库存取和访问的效率,总结了Delphi数据库开发的步骤,便于使用者学习和应用。%Database technology is one of the most important fundamental technologies in the information society.Among many of the database development tools,Delphi is particularly prominent.It performs highly efficient database management system and the latest data analysis method and provides a lot of enterprise components,which adapts to a variety of database structures.Database technology introduces the function application of each parts,the database connection method and the principle based on Delphi platform database program design.By comparing the visiting time of each database connection method after testing program,we know that DBExpress method is better than BDE and ADO,which greatly improves the efficiency of the Delphi programming database access and visiting.The steps of the Delphi database development is summarized to facilitate the users' study and application.

  9. Dietary Supplement Ingredient Database

    Science.gov (United States)

    ... and US Department of Agriculture Dietary Supplement Ingredient Database Toggle navigation Menu Home About DSID Mission Current ... values can be saved to build a small database or add to an existing database for national, ...

  10. International Ventilation Cooling Application Database

    DEFF Research Database (Denmark)

    Holzer, Peter; Psomas, Theofanis Ch.; OSullivan, Paul

    2016-01-01

    The currently running International Energy Agency, Energy and Conservation in Buildings, Annex 62 Ventilative Cooling (VC) project, is coordinating research towards extended use of VC. Within this Annex 62 the joint research activity of International VC Application Database has been carried out, ...

  11. X-Eye: A reference format for eye tracking data to facilitate analyses across databases

    Science.gov (United States)

    Winkler, Stefan; Savoy, Florian M.; Subramanian, Ramanathan

    2014-02-01

    Datasets of images annotated with eye tracking data constitute important ground truth for the development of saliency models, which have applications in many areas of electronic imaging. While comparisons and reviews of saliency models abound, similar comparisons among the eye tracking databases themselves are rare. In an earlier paper, we reviewed the content and purpose of over two dozen databases available in the public domain and discussed their commonalities and differences. A major issue is that the formats of the various datasets vary a lot owing to the nature of tools used for eye movement recordings, and often specialized code is required to use the data for further analysis. In this paper, we therefore propose a common reference format for eye tracking data, together with conversion routines for 16 existing image eye tracking databases to that format. Furthermore, we conduct a few analyses on these datasets as examples of what X-Eye facilitates.

  12. ARTI refrigerant database

    Energy Technology Data Exchange (ETDEWEB)

    Calm, J.M.

    1997-02-01

    The Refrigerant Database is an information system on alternative refrigerants, associated lubricants, and their use in air conditioning and refrigeration. It consolidates and facilitates access to property, compatibility, environmental, safety, application and other information. It provides corresponding information on older refrigerants, to assist manufacturers and those using alterative refrigerants, to make comparisons and determine differences. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included, though some may be added at a later date. The database identifies sources of specific information on various refrigerants. It addresses lubricants including alkylbenzene, polyalkylene glycol, polyolester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents. They are included to accelerate availability of the information and will be completed or replaced in future updates.

  13. ARTI Refrigerant Database

    Energy Technology Data Exchange (ETDEWEB)

    Cain, J.M. (Calm (James M.), Great Falls, VA (United States))

    1993-04-30

    The Refrigerant Database consolidates and facilitates access to information to assist industry in developing equipment using alternative refrigerants. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included. The database identifies sources of specific information on R-32, R-123, R-124, R-125, R-134, R-134a, R-141b, R-142b, R-143a, R-152a, R-245ca, R-290 (propane), R-717 (ammonia), ethers, and others as well as azeotropic and zeotropic blends of these fluids. It addresses lubricants including alkylbenzene, polyalkylene glycol, ester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents to accelerate availability of the information and will be completed or replaced in future updates.

  14. ARTI Refrigerant Database

    Energy Technology Data Exchange (ETDEWEB)

    Cain, J.M. [Calm (James M.), Great Falls, VA (United States)

    1993-04-30

    The Refrigerant Database consolidates and facilitates access to information to assist industry in developing equipment using alternative refrigerants. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included. The database identifies sources of specific information on R-32, R-123, R-124, R-125, R-134, R-134a, R-141b, R-142b, R-143a, R-152a, R-245ca, R-290 (propane), R-717 (ammonia), ethers, and others as well as azeotropic and zeotropic blends of these fluids. It addresses lubricants including alkylbenzene, polyalkylene glycol, ester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents to accelerate availability of the information and will be completed or replaced in future updates.

  15. ARTI refrigerant database

    Energy Technology Data Exchange (ETDEWEB)

    Calm, J.M. [Calm (James M.), Great Falls, VA (United States)

    1998-08-01

    The Refrigerant Database is an information system on alternative refrigerants, associated lubricants, and their use in air conditioning and refrigeration. It consolidates and facilitates access to property, compatibility, environmental, safety, application and other information. It provides corresponding information on older refrigerants, to assist manufactures and those using alternative refrigerants, to make comparisons and determine differences. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included, though some may be added at a later date. The database identifies sources of specific information on many refrigerants including propane, ammonia, water, carbon dioxide, propylene, ethers, and others as well as azeotropic and zeotropic blends of these fluids. It addresses lubricants including alkylbenzene, polyalkylene glycol, polyolester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents. They are included to accelerate availability of the information and will be completed or replaced in future updates.

  16. NoSQL Databases

    OpenAIRE

    2013-01-01

    This thesis deals with database systems referred to as NoSQL databases. In the second chapter, I explain basic terms and the theory of database systems. A short explanation is dedicated to database systems based on the relational data model and the SQL standardized query language. Chapter Three explains the concept and history of the NoSQL databases, and also presents database models, major features and the use of NoSQL databases in comparison with traditional database systems. In the fourth ...

  17. USAID Anticorruption Projects Database

    Data.gov (United States)

    US Agency for International Development — The Anticorruption Projects Database (Database) includes information about USAID projects with anticorruption interventions implemented worldwide between 2007 and...

  18. Collecting Taxes Database

    Data.gov (United States)

    US Agency for International Development — The Collecting Taxes Database contains performance and structural indicators about national tax systems. The database contains quantitative revenue performance...

  19. Database Description - Arabidopsis Phenome Database | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available n accumulated, which is an indispensable resource to improve plant omics studies both on basic and applied research...mutant lines to the phenome to improve experimental research. Inconstancy among them however has inhibited t...s. One is the “RIKEN Phenome Integration of Arabidopsis Mutants”, that allows researchers to search mutants ...seful materials for their experimental research. The other, the “Database of Curated Plant Phenome” focusing

  20. Usability in Scientific Databases

    Directory of Open Access Journals (Sweden)

    Ana-Maria Suduc

    2012-07-01

    Full Text Available Usability, most often defined as the ease of use and acceptability of a system, affects the users' performance and their job satisfaction when working with a machine. Therefore, usability is a very important aspect which must be considered in the process of a system development. The paper presents several numerical data related to the history of the scientific research of the usability of information systems, as it is viewed in the information provided by three important scientific databases, Science Direct, ACM Digital Library and IEEE Xplore Digital Library, at different queries related to this field.

  1. Research and Implementation of Distributed Database Technology%分布式数据库技术的研究与实现

    Institute of Scientific and Technical Information of China (English)

    杨东; 谢菲; 杨晓刚; 何遵文

    2015-01-01

    Distributed Database technology is progeny combining database technology with computer network technology. It involves parallel computing, distribution strategy ,data slice ,query optimization and distributed database concurrency control, transaction processing and recovery, etc. This paper aims to study the key technology of the distributed database, to find a new,general-purpose distributed database model to adapt to a variety of complex application scenarios ,with large data change in response to increasingly challenge.%分布式数据库技术是数据库技术与计算机网络技术[1]相结合的产物,主要技术涉及并行计算、分布策略、数据分片、查询优化以及分布式数据库系统的并发控制[2]、事务处理与恢复技术等。本文旨在通过对分布式数据库关键技术的研究,找到一种新型的、适应多种复杂应用场景的通用型分布式数据库模型,以应对日益凸显的大数据变革带来的挑战。

  2. Research of the methods of association rules in image database%图像数据库关联规则的挖掘方法研究

    Institute of Scientific and Technical Information of China (English)

    王远敏

    2012-01-01

      In multimedia applications,the use of the image database is increasingly widespread. In order to use image database more effectively,many data mining techniques is used in image database.This paper uses FP_tree techniques in data mining to mine the rule in image database and constructs an new image database system.%  在多媒体应用中,图像数据库的使用日趋广泛,为了更有效地使用图像数据库,许多数据挖掘技术被用于图像数据库中。本文使用数据挖掘中的关联规则方法来进一步提高图像数据库的性能,基于此构建了一个图像数据库系统,在这个系统中使用了FP增长算法挖掘图像数据的关联规则。

  3. Database tomography for commercial application

    Science.gov (United States)

    Kostoff, Ronald N.; Eberhart, Henry J.

    1994-01-01

    Database tomography is a method for extracting themes and their relationships from text. The algorithms, employed begin with word frequency and word proximity analysis and build upon these results. When the word 'database' is used, think of medical or police records, patents, journals, or papers, etc. (any text information that can be computer stored). Database tomography features a full text, user interactive technique enabling the user to identify areas of interest, establish relationships, and map trends for a deeper understanding of an area of interest. Database tomography concepts and applications have been reported in journals and presented at conferences. One important feature of the database tomography algorithm is that it can be used on a database of any size, and will facilitate the users ability to understand the volume of content therein. While employing the process to identify research opportunities it became obvious that this promising technology has potential applications for business, science, engineering, law, and academe. Examples include evaluating marketing trends, strategies, relationships and associations. Also, the database tomography process would be a powerful component in the area of competitive intelligence, national security intelligence and patent analysis. User interests and involvement cannot be overemphasized.

  4. Capacity development in food composition database management and nutritional research and education in Central and Eastern European, Middle Eastern and North African countries.

    Science.gov (United States)

    Gurinović, M; Witthöft, C M; Tepšić, J; Ranić, M; Hulshof, P J M; Hollman, P C; Porubska, J; Gohar, A; Debeljak-Martačić, J; Petrović-Oggiano, G; Novaković, R; Glibetić, M; Oshaug, A

    2010-11-01

    Capacity development (CD) in food and nutrition is much more than formal training and includes human resource development, and organisational, institutional and legal framework development with the aim of enhancing nutrition-relevant knowledge and skills to support infrastructural development. The goal of the European Food Information Resource (EuroFIR) Network of Excellence has been to develop and integrate food composition data throughout Europe. EuroFIR joined forces in CD with the United Nations (UN) University and UN System Standing Committee on Nutrition, the Network for Capacity Development in Nutrition in Central and Eastern Europe, the Central and Eastern European Countries Food Data Systems network and with the Middle East and North African Capacity Building Initiative. The aim of this paper is to discuss an inventory of the status of food composition databases (FCDBs) and the training needs of compilers in non-EuroFIR countries in Central and Eastern Europe (CEE) and in the Middle East and North Africa (MENA), and to present the CD achieved through EuroFIR and other network collaborations. Two online questionnaires were created addressing the FCDB status and specific training needs in countries of the targeted regions. Data were collected during 2006-2008 and then analysed. Subsequently, CD activities were organised. Contacts were established in 19 CEE and 7 MENA countries, of which several had national food composition tables, but no electronic versions. Education, training, workshops, networking and the sharing of experiences were uniformly requested. Subsequently, CD activities in EuroFIR were organised focussing on food composition courses, exchange visits, workshops and individual training for PhD students, junior scientists and other staff categories, as well as conferences linked to food composition research and food information. To facilitate CD activities, EuroFIR has signed a Memorandum of Understanding with the Czech Republic, Hungary

  5. Predicting return visits to the emergency department for pediatric patients: Applying supervised learning techniques to the Taiwan National Health Insurance Research Database.

    Science.gov (United States)

    Hu, Ya-Han; Tai, Chun-Tien; Chen, Solomon Chih-Cheng; Lee, Hai-Wei; Sung, Sheng-Feng

    2017-06-01

    Return visits (RVs) to the emergency department (ED) consume medical resources and may represent a patient safety issue. The occurrence of unexpected RVs is considered a performance indicator for ED care quality. Because children are susceptible to medical errors and utilize considerable ED resources, knowing the factors that affect RVs in pediatric patients helps improve the quality of pediatric emergency care. We collected data on visits made by patients aged ≤18years to EDs from the National Health Insurance Research Database. The outcome of interest was a RV within 3days of the initial visit. Potential factors were categorized into demographics, medical history, features of ED visits, physician characteristics, hospital characteristics, and treatment-seeking behavior. A multivariate logistic regression was used to identify independent predictors of RVs. We compared the performance of various data mining techniques, including Naïve Bayes, classification and regression tree (CART), random forest, and logistic regression, in predicting RVs. Finally, we developed a decision tree to stratify the risk of RVs. Of 125,940 visits, 6,282 (5.0%) were followed by a RV within 3 days. Predictors of RVs included younger age, higher acuity, intravenous fluid, more examination types, complete blood count, consultation, lower hospital level, hospitalization within one week before the initial visit, frequent ED visits in the past one year, and visits made in Spring or on Saturdays. Patients with allergic diseases and those underwent ultrasound examination were less likely to return. Decision tree models performed better in predicting RVs in terms of area under curve. The decision tree constructed using the CART technique showed that the number of ED visits in the past one year, diagnosis category, testing of complete blood count, and age were important discriminators of risk of RVs. We identified several factors which are associated with RVs to the ED in pediatric patients

  6. Design and internal validation of an obstetric early warning score: secondary analysis of the Intensive Care National Audit and Research Centre Case Mix Programme database.

    Science.gov (United States)

    Carle, C; Alexander, P; Columb, M; Johal, J

    2013-04-01

    We designed and internally validated an aggregate weighted early warning scoring system specific to the obstetric population that has the potential for use in the ward environment. Direct obstetric admissions from the Intensive Care National Audit and Research Centre's Case Mix Programme Database were randomly allocated to model development (n = 2240) or validation (n = 2200) sets. Physiological variables collected during the first 24 h of critical care admission were analysed. Logistic regression analysis for mortality in the model development set was initially used to create a statistically based early warning score. The statistical score was then modified to create a clinically acceptable early warning score. Important features of this clinical obstetric early warning score are that the variables are weighted according to their statistical importance, a surrogate for the FI O2 /Pa O2 relationship is included, conscious level is assessed using a simplified alert/not alert variable, and the score, trigger thresholds and response are consistent with the new non-obstetric National Early Warning Score system. The statistical and clinical early warning scores were internally validated using the validation set. The area under the receiver operating characteristic curve was 0.995 (95% CI 0.992-0.998) for the statistical score and 0.957 (95% CI 0.923-0.991) for the clinical score. Pre-existing empirically designed early warning scores were also validated in the same way for comparison. The area under the receiver operating characteristic curve was 0.955 (95% CI 0.922-0.988) for Swanton et al.'s Modified Early Obstetric Warning System, 0.937 (95% CI 0.884-0.991) for the obstetric early warning score suggested in the 2003-2005 Report on Confidential Enquiries into Maternal Deaths in the UK, and 0.973 (95% CI 0.957-0.989) for the non-obstetric National Early Warning Score. This highlights that the new clinical obstetric early warning score has an excellent ability to

  7. Difference in patient profiles and outcomes in Japanese versus American patients undergoing coronary revascularization (collaborative study by CREDO-Kyoto and the Texas Heart Institute Research Database).

    Science.gov (United States)

    Kohsaka, Shun; Kimura, Takeshi; Goto, Masashi; Lee, Vei-Vei; Elayda, Macarthur; Furukawa, Yutaka; Fukushima, Masanori; Komeda, Masashi; Sakata, Ryuuzou; Willerson, James T; Wilson, James M; Kita, Toru

    2010-06-15

    Although coronary revascularization is common in both Japan and the United States (US), no direct comparison has been performed to demonstrate differences in the clinical characteristics and long-term outcomes of patients in these 2 countries. We analyzed the preprocedural, in-hospital, and long-term data from the Coronary Revascularization Demonstrating Outcome registry (Kyoto, Japan) and the Texas Heart Institute Research Database (Houston, Texas) of 16,100 patients who had undergone elective, initial percutaneous coronary intervention or coronary artery bypass grafting. The Japanese procedures were performed from 2000 to 2002 (n = 8,871, follow-up period 3.5 years, interquartile range 2.6 to 4.3) and the US procedures from 1999 to 2003 (n = 7,229, follow-up period 5.2 years, interquartile range 3.8 to 6.5). The Japanese patients tended to be older (mean age 67.2 vs 62.7 years; p <0.001), to smoke (52.9% vs 46.0%; p <0.001), and to have diabetes (39.2% vs 31.0%; p <0.001) and stroke (16.4% vs 5.0%; p <0.001). The US patients were more obese (body mass index 23.7 vs 29.3 kg/m(2); p <0.001), with greater rates of systemic atherosclerotic disease. Both groups had a similar in-hospital mortality rate (Japanese patients 0.9% vs US patients 1.1%; p = 0.19) and crude long-term mortality rate (Japanese patients 27.7/1,000 person-years, US patients 28.2/1,000 person-years; p = 0.35). After adjustment for known predictors, the US group had greater long-term mortality than the Japanese group (hazard ratio 1.71, 95% confidence interval 1.50 to 1.95; p <0.001). This finding was consistent among all high-risk subgroups. In conclusion, the 2 registries showed similar crude outcomes but important differences in patient risk factors such as obesity. In the adjusted analysis, the Japanese patients had better outcomes than did the US patients. Additional study is needed to assess the effect of ethnic and risk factor variations on coronary artery disease.

  8. An evaluation of Birmingham Own Health® telephone care management service among patients with poorly controlled diabetes. a retrospective comparison with the General Practice Research Database

    Directory of Open Access Journals (Sweden)

    Adab Peymané

    2011-09-01

    Full Text Available Abstract Background Telephone-based care management programmes have been shown to improve health outcomes in some chronic diseases. Birmingham Own Health® is a telephone-based care service (nurse-delivered motivational coaching and support for self-management and lifestyle change for patients with poorly controlled diabetes, delivered in Birmingham, UK. We used a novel method to evaluate its effectiveness in a real-life setting. Methods Retrospective cohort study in the UK. 473 patients aged ≥ 18 years with diabetes enrolled onto Birmingham Own Health® (intervention cohort and with > 90 days follow-up, were each matched by age and sex to up to 50 patients with diabetes registered with the General Practice Research Database (GPRD to create a pool of 21,052 controls (control cohort. Controls were further selected from the main control cohort, matching as close as possible to the cases for baseline test levels, followed by as close as possible length of follow-up (within +/-30 days limits and within +/-90 days baseline test date. The aim was to identify a control group with as similar distribution of prognostic factors to the cases as possible. Effect sizes were computed using linear regression analysis adjusting for age, sex, deprivation quintile, length of follow-up and baseline test levels. Results After adjusting for baseline values and other potential confounders, the intervention showed significant mean reductions among people with diabetes of 0.3% (95%CI 0.1, 0.4% in HbA1c; 3.5 mmHg (1.5, 5.5 in systolic blood pressure, 1.6 mmHg (0.4, 2.7 in diastolic blood pressure and 0.7 unit reduction (0.3, 1.0 in BMI, over a mean follow-up of around 10 months. Only small effects were seen on average on serum cholesterol levels (0.1 mmol/l reduction (0.1, 0.2. More marked effects were seen for each clinical outcome among patients with worse baseline levels. Conclusions Despite the limitations of the study design, the results are consistent with the

  9. A Call to Arms: Revisiting Database Design

    CERN Document Server

    Badia, Antonio

    2011-01-01

    Good database design is crucial to obtain a sound, consistent database, and - in turn - good database design methodologies are the best way to achieve the right design. These methodologies are taught to most Computer Science undergraduates, as part of any Introduction to Database class. They can be considered part of the "canon", and indeed, the overall approach to database design has been unchanged for years. Moreover, none of the major database research assessments identify database design as a strategic research direction. Should we conclude that database design is a solved problem? Our thesis is that database design remains a critical unsolved problem. Hence, it should be the subject of more research. Our starting point is the observation that traditional database design is not used in practice - and if it were used it would result in designs that are not well adapted to current environments. In short, database design has failed to keep up with the times. In this paper, we put forth arguments to support o...

  10. The Danish Smoking Cessation Database

    DEFF Research Database (Denmark)

    Rasmussen, Mette; Tønnesen, Hanne

    2016-01-01

    , place or person working with a preventive aim. There are no age limits for registering a smoker in the database. Data collection: The SCDB contains prospectively collected baseline and outcome data on SC clinics, interventions, and individual smokers. Baseline data include socio-economic, demographic......Background: The Danish Smoking Cessation Database (SCDB) was established in 2001 as the first national healthcare register within the field of health promotion. Aim of the database: The aim of the SCDB is to document and evaluate smoking cessation (SC) interventions to assess and improve...... their quality. The database was also designed to function as a basis for register-based research projects. Study population The population includes smokers in Denmark who have been receiving a face-to-face SC intervention offered by an SC clinic affiliated with the SCDB. SC clinics can be any organisation...

  11. SmallSat Database

    Science.gov (United States)

    Petropulos, Dolores; Bittner, David; Murawski, Robert; Golden, Bert

    2015-01-01

    The SmallSat has an unrealized potential in both the private industry and in the federal government. Currently over 70 companies, 50 universities and 17 governmental agencies are involved in SmallSat research and development. In 1994, the U.S. Army Missile and Defense mapped the moon using smallSat imagery. Since then Smart Phones have introduced this imagery to the people of the world as diverse industries watched this trend. The deployment cost of smallSats is also greatly reduced compared to traditional satellites due to the fact that multiple units can be deployed in a single mission. Imaging payloads have become more sophisticated, smaller and lighter. In addition, the growth of small technology obtained from private industries has led to the more widespread use of smallSats. This includes greater revisit rates in imagery, significantly lower costs, the ability to update technology more frequently and the ability to decrease vulnerability of enemy attacks. The popularity of smallSats show a changing mentality in this fast paced world of tomorrow. What impact has this created on the NASA communication networks now and in future years? In this project, we are developing the SmallSat Relational Database which can support a simulation of smallSats within the NASA SCaN Compatability Environment for Networks and Integrated Communications (SCENIC) Modeling and Simulation Lab. The NASA Space Communications and Networks (SCaN) Program can use this modeling to project required network support needs in the next 10 to 15 years. The SmallSat Rational Database could model smallSats just as the other SCaN databases model the more traditional larger satellites, with a few exceptions. One being that the smallSat Database is designed to be built-to-order. The SmallSat database holds various hardware configurations that can be used to model a smallSat. It will require significant effort to develop as the research material can only be populated by hand to obtain the unique data

  12. Network Hatred:Obstruction and Decomposition of Order Construction in Virtual Public Domain%网络怨恨:虚拟公共领域秩序建构的梗阻与消解

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    网络怨恨既是一种情感体验,也是一种生存状态。越来越多的虚拟社会现象表明,网络怨恨已经出现了一定程度上的弥散,虚拟公共领域秩序建构因而面临着无法回避的现实梗阻。网络怨恨导致无直接利益冲突的网络暴力频现,基于网络民粹主义的阶层对抗遭遇激化,同时网络空间出现颠覆性的价值位移。究其根源,网络怨恨与网络世界的平等理念、现代社会的竞争意识和难以克服的现实困境密切相关。需要通过提升虚拟公共领域的公共理性,适度满足网络怨恨的宣泄需求,构建包容性发展的网络监督体系,纠正虚拟公共领域中的价值位移等途径,才能真正消解网络怨恨,实现虚拟公共领域的秩序化运行。%Network hatred is not only an emotional experience , but also a living state.It is suggested by more and more virtual social phenomenon that network hatred has been dispersing in the new public domain and has become virtual social emotions in the keynote.Thus, order construction in the virtual public domain has been ex-posed to practical obstructions which cannot be evaded.As a result of network hatred , network violence , which has no direct conflict of interests , frequently shows up , and network populism-based hierarchical confrontation is triggered , and concurrently , subversive value displacement shows up in network space.Tracing to the source , network hatred is closely related to the equality philosophy of network world , the sense of competition in the modern society and the insurmountable practical difficulties.Only by such channels as improving public reason of the virtual public domain , moderately satisfying the needs for unbosoming network hatred , constructing net-work supervision system under inclusive development and correcting value displacement in the virtual public do -main, can network hatred be truly decomposed and regularized operation of the

  13. Based on the Oracle Database Performance Adjustment and Optimization Research%基于Oracle数据库系统的优化与性能调整研究

    Institute of Scientific and Technical Information of China (English)

    刘哲

    2012-01-01

    Oracle performance optimizer will directly affect the efficient operation of database application sys- tem. This article discusses the Oracle database performance optimization objectives, and analyzes the factors affecting performance in every other sides. And the adjustment and optimization of database,memory,I/O, and SQL statements is presented and explained in detail. And finally proved by experiments,after optimiza- tion, Oracle database performance has been improved and enhanced.%指出了Oracle数据库性能直接影响到Oracle数据库应用系统的运行效率,分析了Oracle数据库性能优化的目标及影响Oracle数据库系统性能的因素,探讨了数据库的优化、内存优化、I/O优化和SQL语句优化技术,实验表明:经过优化后,Oracle数据库性能得到了改善和提高。

  14. Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of patients with systemic sclerosis.

    NARCIS (Netherlands)

    Allanore, Y.; Meune, C.; Vonk, M.C.; Airo, P.; Hachulla, E.; Caramaschi, P.; Riemekasten, G.; Cozzi, F.; Beretta, L.; Derk, C.T.; Komocsi, A.; Farge, D.; Balbir, A.; Riccieri, V.; Distler, O.; Chiala, A.; Papa, N.D.; Simic, K.P.; Ghio, M.; Stamenkovic, B.; Rednic, S.; Host, N.; Pellerito, R.; Zegers, E.; Kahan, A.; Walker, U.A.; Matucci-Cerinic, M.

    2010-01-01

    OBJECTIVES: To measure the prevalence of, and factors associated with, left ventricular (LV) dysfunction in systemic sclerosis (SSc). METHODS: The EUSTAR database was first searched. A case-control study of a patient subset was then performed to further identify independent factors associated with

  15. Databases of the marine metagenomics

    KAUST Repository

    Mineta, Katsuhiko

    2015-10-28

    The metagenomic data obtained from marine environments is significantly useful for understanding marine microbial communities. In comparison with the conventional amplicon-based approach of metagenomics, the recent shotgun sequencing-based approach has become a powerful tool that provides an efficient way of grasping a diversity of the entire microbial community at a sampling point in the sea. However, this approach accelerates accumulation of the metagenome data as well as increase of data complexity. Moreover, when metagenomic approach is used for monitoring a time change of marine environments at multiple locations of the seawater, accumulation of metagenomics data will become tremendous with an enormous speed. Because this kind of situation has started becoming of reality at many marine research institutions and stations all over the world, it looks obvious that the data management and analysis will be confronted by the so-called Big Data issues such as how the database can be constructed in an efficient way and how useful knowledge should be extracted from a vast amount of the data. In this review, we summarize the outline of all the major databases of marine metagenome that are currently publically available, noting that database exclusively on marine metagenome is none but the number of metagenome databases including marine metagenome data are six, unexpectedly still small. We also extend our explanation to the databases, as reference database we call, that will be useful for constructing a marine metagenome database as well as complementing important information with the database. Then, we would point out a number of challenges to be conquered in constructing the marine metagenome database.

  16. Databases of the marine metagenomics.

    Science.gov (United States)

    Mineta, Katsuhiko; Gojobori, Takashi

    2016-02-01

    The metagenomic data obtained from marine environments is significantly useful for understanding marine microbial communities. In comparison with the conventional amplicon-based approach of metagenomics, the recent shotgun sequencing-based approach has become a powerful tool that provides an efficient way of grasping a diversity of the entire microbial community at a sampling point in the sea. However, this approach accelerates accumulation of the metagenome data as well as increase of data complexity. Moreover, when metagenomic approach is used for monitoring a time change of marine environments at multiple locations of the seawater, accumulation of metagenomics data will become tremendous with an enormous speed. Because this kind of situation has started becoming of reality at many marine research institutions and stations all over the world, it looks obvious that the data management and analysis will be confronted by the so-called Big Data issues such as how the database can be constructed in an efficient way and how useful knowledge should be extracted from a vast amount of the data. In this review, we summarize the outline of all the major databases of marine metagenome that are currently publically available, noting that database exclusively on marine metagenome is none but the number of metagenome databases including marine metagenome data are six, unexpectedly still small. We also extend our explanation to the databases, as reference database we call, that will be useful for constructing a marine metagenome database as well as complementing important information with the database. Then, we would point out a number of challenges to be conquered in constructing the marine metagenome database.

  17. RESEARCH ON ALL NEGATIVE ASSOCIATION RULES MINING IN A DATABASE%数据库中全部负关联规则挖掘研究

    Institute of Scientific and Technical Information of China (English)

    李红; 宗瑜; 解浚源

    2011-01-01

    数据库中关联规则信息是知识的表述形式之一,负关联规则挖掘是数据库关联信息挖掘的重要研究内容,具有广泛的应用范围.现有的挖掘方法不能获取数据库中全部的负关联规则,考虑从数据库中提取全部的负关联规则,通过(1)扫描数据库建立数据库频繁模式树DFP-tree( Database Frequent Pattern tree);(2)在精简DFP-tree的基础上获取全部极小非频繁项集ASI;(3)对ASI中极大频繁项集的向上闭包,得到全部非频繁项集;(4)在此基础上采用相关度作为规则兴趣度量之一提取负关联规则.理论和实验表明算法的正确性和效率.%In a database, associated rule information is one of the representation formats for knowledge. Negative association rule mining is so important to study in database association information mining that it bears wide application value. Existing mining approaches can not obtain all negative rules from a database. The paper considers to extract all negative association rules from a database through: (1) scanning the database to build a database frequent pattern tree called DFP-tree; (2) acquiring based on pruning the DFP-tree all small infrequent itemsets; (3) acquiring via upward closure packets of large frequent itemsets in ASI all infrequent itemsets; (4) based on the previous 3 steps adopting correlation metric as one of rule interest measurements to extract negative association rules. Theories and experiments validate the correctness and efficiency of the presented algorithm.

  18. Cloud Databases: A Paradigm Shift in Databases

    Directory of Open Access Journals (Sweden)

    Indu Arora

    2012-07-01

    Full Text Available Relational databases ruled the Information Technology (IT industry for almost 40 years. But last few years have seen sea changes in the way IT is being used and viewed. Stand alone applications have been replaced with web-based applications, dedicated servers with multiple distributed servers and dedicated storage with network storage. Cloud computing has become a reality due to its lesser cost, scalability and pay-as-you-go model. It is one of the biggest changes in IT after the rise of World Wide Web. Cloud databases such as Big Table, Sherpa and SimpleDB are becoming popular. They address the limitations of existing relational databases related to scalability, ease of use and dynamic provisioning. Cloud databases are mainly used for data-intensive applications such as data warehousing, data mining and business intelligence. These applications are read-intensive, scalable and elastic in nature. Transactional data management applications such as banking, airline reservation, online e-commerce and supply chain management applications are write-intensive. Databases supporting such applications require ACID (Atomicity, Consistency, Isolation and Durability properties, but these databases are difficult to deploy in the cloud. The goal of this paper is to review the state of the art in the cloud databases and various architectures. It further assesses the challenges to develop cloud databases that meet the user requirements and discusses popularly used Cloud databases.

  19. 基于数据库分类的deep web爬行器研究%Research on Deep Web Crawler Based on Database Classification

    Institute of Scientific and Technical Information of China (English)

    郭少友; 赵善义; 李建平; 王斌

    2011-01-01

    在现有相关研究的基础上,设计一种基于数据库分类的deepweb爬行器。该爬行器首先从抓取的网页中识别出deepweb数据库的入口表单,然后采用查询探测方法对数据库进行自动分类,并根据分类结果来选取一组合适的关键词作为查询词,自动填写入口表单中的文本框并向数据库提出查询请求。实验结果表明,基于数据库分类的deepweb爬行器的爬行效果要优于基于指定查询词的deepweb行器的爬行效果。%On the basis of related work, this paper designs a deep web crawler based on database classification. First, it identifies the entry forms of deep web databases from downloaded pages, and then classifies deep web databases with query probing . According to the classification results, some proper keywords are selected as query terms, and automatically filled in the text boxes of these forms to query deep web databases. The experimental results show that the crawling effect of the crawler based on database classification is superior to that of the crawler based on specified query terms.

  20. Logical database design principles

    CERN Document Server

    Garmany, John; Clark, Terry

    2005-01-01

    INTRODUCTION TO LOGICAL DATABASE DESIGNUnderstanding a Database Database Architectures Relational Databases Creating the Database System Development Life Cycle (SDLC)Systems Planning: Assessment and Feasibility System Analysis: RequirementsSystem Analysis: Requirements Checklist Models Tracking and Schedules Design Modeling Functional Decomposition DiagramData Flow Diagrams Data Dictionary Logical Structures and Decision Trees System Design: LogicalSYSTEM DESIGN AND IMPLEMENTATION The ER ApproachEntities and Entity Types Attribute Domains AttributesSet-Valued AttributesWeak Entities Constraint

  1. An Interoperable Cartographic Database

    OpenAIRE

    Slobodanka Ključanin; Zdravko Galić

    2007-01-01

    The concept of producing a prototype of interoperable cartographic database is explored in this paper, including the possibilities of integration of different geospatial data into the database management system and their visualization on the Internet. The implementation includes vectorization of the concept of a single map page, creation of the cartographic database in an object-relation database, spatial analysis, definition and visualization of the database content in the form of a map on t...

  2. 高校图书馆数据库利用率统计与绩效的研究%Empirical Research on the Usage Statistics and Performance of Databases in University Libraries

    Institute of Scientific and Technical Information of China (English)

    刘佳音; 邓同庆

    2012-01-01

    电子资源的建设与利用逐渐成为衡量一个图书馆实力的重要指标。本文基于高校图书馆的电子资源特别是外文数据库利用主要指标的统计,研究数据库的利用率以及电子资源的实际需求。通过对各数据库的投入支出进行绩效分析以及同类型数据库之间的横向比较,为图书馆馆藏资源建设提供有针对性的指导意见。%With the continuous development of digital libraries,the construction and utilization of electronic resources have become important indicators of the strength of a library.Based on the statistical data of main indicators of electronic resources usage in the university library,especially databases of foreign language,the overall utilization of various databases and actual needs of electronic resources are researched.Performance ratios of investment and expenditures of each database are evaluated and horizontal comparison are made among the same type databases,so as to provide targeted guidance and advices for library resources construction and information literacy education.

  3. Kazusa Marker DataBase: a database for genomics, genetics, and molecular breeding in plants

    OpenAIRE

    2014-01-01

    In order to provide useful genomic information for agronomical plants, we have established a database, the Kazusa Marker DataBase (http://marker.kazusa.or.jp). This database includes information on DNA markers, e.g., SSR and SNP markers, genetic linkage maps, and physical maps, that were developed at the Kazusa DNA Research Institute. Keyword searches for the markers, sequence data used for marker development, and experimental conditions are also available through this database. Currently, 10...

  4. 基于哈希函数的数据库查询技术的研究%Research on Database Query Technology Based on Hash Function

    Institute of Scientific and Technical Information of China (English)

    贾丹; 佟玉军; 陈文实

    2012-01-01

    分析了目前常用的哈希函数和数据库传统的查找方式存在的不足,提出了一种新的思想,将哈希函数与数据库设计相结合,直接定位到所要查找的记录,以提高查找效率。%Commonly used hash functions and shortcoming of database traditional search method were analyzed, a new idea was proposed, which combines hash function with database design,locates the record that will be searched directly and to the effect improves search efficiency.

  5. Research of Parallel Query Processing Algorithm In Object-Oriented Database%面向对象数据库的并行查询处理

    Institute of Scientific and Technical Information of China (English)

    王意洁; 王勇军; 胡守仁

    2000-01-01

    In this paper, according to the features of the object-oriented database and its query, the stage-by-stage executing strategy,the class-based hybrid data placement strategy, the mark-based data operation parallel executing algorithm and the semi-join-based parallel query processing algorithm are proposed.the correctness of the algorithm is proved.and the results of performance evaluation are given.

  6. Oceans of Data: In what ways can learning research inform the development of electronic interfaces and tools for use by students accessing large scientific databases?

    Science.gov (United States)

    Krumhansl, R. A.; Foster, J.; Peach, C. L.; Busey, A.; Baker, I.

    2012-12-01

    The practice of science and engineering is being revolutionized by the development of cyberinfrastructure for accessing near real-time and archived observatory data. Large cyberinfrastructure projects have the potential to transform the way science is taught in high school classrooms, making enormous quantities of scientific data available, giving students opportunities to analyze and draw conclusions from many kinds of complex data, and providing students with experiences using state-of-the-art resources and techniques for scientific investigations. However, online interfaces to scientific data are built by scientists for scientists, and their design can significantly impede broad use by novices. Knowledge relevant to the design of student interfaces to complex scientific databases is broadly dispersed among disciplines ranging from cognitive science to computer science and cartography and is not easily accessible to designers of educational interfaces. To inform efforts at bridging scientific cyberinfrastructure to the high school classroom, Education Development Center, Inc. and the Scripps Institution of Oceanography conducted an NSF-funded 2-year interdisciplinary review of literature and expert opinion pertinent to making interfaces to large scientific databases accessible to and usable by precollege learners and their teachers. Project findings are grounded in the fundamentals of Cognitive Load Theory, Visual Perception, Schemata formation and Universal Design for Learning. The Knowledge Status Report (KSR) presents cross-cutting and visualization-specific guidelines that highlight how interface design features can address/ ameliorate challenges novice high school students face as they navigate complex databases to find data, and construct and look for patterns in maps, graphs, animations and other data visualizations. The guidelines present ways to make scientific databases more broadly accessible by: 1) adjusting the cognitive load imposed by the user

  7. 基于R-PEM的Web数据库安全机制研究%Research on the Web Database Security Based on R-PEM

    Institute of Scientific and Technical Information of China (English)

    罗军; 韩坚华; 汪双兔

    2014-01-01

    Aims at the security problem of relational Web database, in the overall framework of the mechanism on the basis of credible, designs the structure model of Web database based on R-PEM. The use of security authentication interfaces and HIP with credible mechanism to en-sure the effective and security operation of Web database. Experimental analysis shows, this security mechanism is not only resisitant to a variety of network intrusion of violence and aggressive behavior, such as computer viruses, DoS attacks, but also generates Web database system protection security policies and efficient defense system in complex mobile network conditions.%针对目前关系型Web数据库出现的多重系统安全问题,在可信机制的整体框架基础之上,设计一种基于关系安全策略机制(R-PEM)的数据库结构体系模型。利用可信机制与主机标识协议体系的安全验证接口,保证Web数据库安全有效地运行。实验分析可知,此安全机制不仅能够抵抗多种暴力网络入侵与攻击行为,例如计算机病毒入侵、DoS攻击等,同时也能在复杂的移动网络条件下,生成Web数据库系统防护安全策略,形成高效的防御体系。

  8. DMTB: the magnetotactic bacteria database

    Science.gov (United States)

    Pan, Y.; Lin, W.

    2012-12-01

    Magnetotactic bacteria (MTB) are of interest in biogeomagnetism, rock magnetism, microbiology, biomineralization, and advanced magnetic materials because of their ability to synthesize highly ordered intracellular nano-sized magnetic minerals, magnetite or greigite. Great strides for MTB studies have been made in the past few decades. More than 600 articles concerning MTB have been published. These rapidly growing data are stimulating cross disciplinary studies in such field as biogeomagnetism. We have compiled the first online database for MTB, i.e., Database of Magnestotactic Bacteria (DMTB, http://database.biomnsl.com). It contains useful information of 16S rRNA gene sequences, oligonucleotides, and magnetic properties of MTB, and corresponding ecological metadata of sampling sites. The 16S rRNA gene sequences are collected from the GenBank database, while all other data are collected from the scientific literature. Rock magnetic properties for both uncultivated and cultivated MTB species are also included. In the DMTB database, data are accessible through four main interfaces: Site Sort, Phylo Sort, Oligonucleotides, and Magnetic Properties. References in each entry serve as links to specific pages within public databases. The online comprehensive DMTB will provide a very useful data resource for researchers from various disciplines, e.g., microbiology, rock magnetism and paleomagnetism, biogeomagnetism, magnetic material sciences and others.

  9. Teaching Research of Database Theory and Application Course%《数据库原理及应用》课程的教学法研究

    Institute of Scientific and Technical Information of China (English)

    张燕; 毛莉君

    2012-01-01

    According to the current database technology penetration by a computer professional to non-computer professional features,combined with each specialized in different professional direction and goal,the purpose of teaching methods and teaching points from the database of professional learning,and cultivate the talent is more suitable for the development of modem database technology to erdianee the students' interest and practical ability.%针对目前数据库技术已经由计算机专业渗透到了非计算机专业的特点,结合每个专业不同的专业方向和培养目标,从各专业的数据库学习目的、教学的方法和教学要点等方面进行了探讨,以提高学生的学习兴趣和动手能力,培养出更适合现代数据库技术发展的人才。

  10. SQL Server Database Intrusion Detection System Research%SQL Server数据库入侵检测系统的研究

    Institute of Scientific and Technical Information of China (English)

    郭可

    2016-01-01

    with the rapid development of network technology, the Internet has spread in the life of people, network attack has be-come a developing needs to solve an important issue. The traditional firewall technology already cannot satisfy the needs of In-ternet security, intrusion detection technology in improving the security of network database can provide effective protection. In this paper, the intrusion detection system and database intrusion detection technology has carried on the simple analysis, SQL server database intrusion detection system design method is proposed.%随着网络技术的迅速发展,互联网在人们的生活中已经普及,网络攻击也成为网络发展中需要解决的一个重要的课题。传统的防火墙技术已经不能满足互联网安全的需要,数据库的入侵检测技术在提高网络的安全性方面可以提供有效的保障。该文对入侵检测系统和数据库入侵检测技术进行了简单的分析,提出了SQL server数据库入侵检测系统设计方法。

  11. The Danish Anaesthesia Database

    Directory of Open Access Journals (Sweden)

    Antonsen K

    2016-10-01

    Full Text Available Kristian Antonsen,1 Charlotte Vallentin Rosenstock,2 Lars Hyldborg Lundstrøm2 1Board of Directors, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Capital Region of Denmark, Denmark; 2Department of Anesthesiology, Copenhagen University Hospital, Nordsjællands Hospital-Hillerød, Capital Region of Denmark, Denmark Aim of database: The aim of the Danish Anaesthesia Database (DAD is the nationwide collection of data on all patients undergoing anesthesia. Collected data are used for quality assurance, quality development, and serve as a basis for research projects. Study population: The DAD was founded in 2004 as a part of Danish Clinical Registries (Regionernes Kliniske Kvalitetsudviklings Program [RKKP]. Patients undergoing general anesthesia, regional anesthesia with or without combined general anesthesia as well as patients under sedation are registered. Data are retrieved from public and private anesthesia clinics, single-centers as well as multihospital corporations across Denmark. In 2014 a total of 278,679 unique entries representing a national coverage of ~70% were recorded, data completeness is steadily increasing. Main variable: Records are aggregated for determining 13 defined quality indicators and eleven defined complications all covering the anesthetic process from the preoperative assessment through anesthesia and surgery until the end of the postoperative recovery period. Descriptive data: Registered variables include patients' individual social security number (assigned to all Danes and both direct patient-related lifestyle factors enabling a quantification of patients' comorbidity as well as variables that are strictly related to the type, duration, and safety of the anesthesia. Data and specific data combinations can be extracted within each department in order to monitor patient treatment. In addition, an annual DAD report is a benchmark for departments nationwide. Conclusion: The DAD is covering the

  12. Database Description - RMOS | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us RMOS Database Description General information of database Database name RMOS Alternative nam...arch Unit Shoshi Kikuchi E-mail : Database classification Plant databases - Rice Microarray Data and other Gene Expression Database...s Organism Taxonomy Name: Oryza sativa Taxonomy ID: 4530 Database description The Ric...e Microarray Opening Site is a database of comprehensive information for Rice Mic...es and manner of utilization of database You can refer to the information of the

  13. AERONET's Development and Contributions through Two Decades of Aerosol Research

    Science.gov (United States)

    Holben, B. N.

    2016-12-01

    The name Brent Holben has been synonymous with AERONET since it's inception nearly two and a half decades ago. Like most scientific endeavors, progress relies on collaboration, persistence and the occasional good idea at the right time. And so it is with AERONET. I will use this opportunity to trace the history of AERONET's development and the scientific achievements that we, as a community, have developed and profited from in our research and understanding of aerosols, describe measurements from this simple instrument applied on a grand scale that created new research opportunities and most importantly acknowledge those that have been and continue to be key in AERONET contributions to aerosol science. Born from a need to remove atmospheric effects in remotely sensed data in the 1980's, molded at a confluence of ideas and shaped as a public domain database, the program has grown from a prototype instrument in 1992 designed to routinely monitor biomass burning aerosol optical depth to over 600 globally distributed sites providing near real-time aerosol properties for satellite validation, assimilation in models and access for numerous research projects. Although standardization and calibration are fundamental elements for scientific success, development for the scientific needs of the community drive new approaches for reprocessing archival data and making new measurements. I'll discuss these and glimpse into the future for AERONET.

  14. Computerized comprehensive data analysis of Lung Imaging Database Consortium (LIDC)

    OpenAIRE

    Tan, Jun; Pu, Jiantao; Zheng, Bin; Wang, Xingwei; Leader, Joseph K.

    2010-01-01

    Purpose: Lung Image Database Consortium (LIDC) is the largest public CT image database of lung nodules. In this study, the authors present a comprehensive and the most updated analysis of this dynamically growing database under the help of a computerized tool, aiming to assist researchers to optimally use this database for lung cancer related investigations.

  15. Overview of selected molecular biological databases

    Energy Technology Data Exchange (ETDEWEB)

    Rayl, K.D.; Gaasterland, T.

    1994-11-01

    This paper presents an overview of the purpose, content, and design of a subset of the currently available biological databases, with an emphasis on protein databases. Databases included in this summary are 3D-ALI, Berlin RNA databank, Blocks, DSSP, EMBL Nucleotide Database, EMP, ENZYME, FSSP, GDB, GenBank, HSSP, LiMB, PDB, PIR, PKCDD, ProSite, and SWISS-PROT. The goal is to provide a starting point for researchers who wish to take advantage of the myriad available databases. Rather than providing a complete explanation of each database, we present its content and form by explaining the details of typical entries. Pointers to more complete ``user guides`` are included, along with general information on where to search for a new database.

  16. Danish Palliative Care Database

    Directory of Open Access Journals (Sweden)

    Groenvold M

    2016-10-01

    Full Text Available Mogens Groenvold,1,2 Mathilde Adsersen,1 Maiken Bang Hansen1 1The Danish Palliative Care Database (DPD Secretariat, Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, 2Department of Public Health, University of Copenhagen, Copenhagen, Denmark Aims: The aim of the Danish Palliative Care Database (DPD is to monitor, evaluate, and improve the clinical quality of specialized palliative care (SPC (ie, the activity of hospital-based palliative care teams/departments and hospices in Denmark. Study population: The study population is all patients in Denmark referred to and/or in contact with SPC after January 1, 2010. Main variables: The main variables in DPD are data about referral for patients admitted and not admitted to SPC, type of the first SPC contact, clinical and sociodemographic factors, multidisciplinary conference, and the patient-reported European Organisation for Research and Treatment of Cancer Quality of Life Questionaire-Core-15-Palliative Care questionnaire, assessing health-related quality of life. The data support the estimation of currently five quality of care indicators, ie, the proportions of 1 referred and eligible patients who were actually admitted to SPC, 2 patients who waited <10 days before admission to SPC, 3 patients who died from cancer and who obtained contact with SPC, 4 patients who were screened with European Organisation for Research and Treatment of Cancer Quality of Life Questionaire-Core-15-Palliative Care at admission to SPC, and 5 patients who were discussed at a multidisciplinary conference. Descriptive data: In 2014, all 43 SPC units in Denmark reported their data to DPD, and all 9,434 cancer patients (100% referred to SPC were registered in DPD. In total, 41,104 unique cancer patients were registered in DPD during the 5 years 2010–2014. Of those registered, 96% had cancer. Conclusion: DPD is a national clinical quality database for SPC having clinically relevant variables and high data

  17. Data-Based Teacher Development.

    Science.gov (United States)

    Borg, Simon

    1998-01-01

    Describes how data from English language teaching (ELT) classroom research can be exploited in teacher development activities. The contribution data-based activities can make to teacher development is outlined, and examples that illustrate the principles underlying their design are presented. A case is made for using such activities to facilitate…

  18. The COMPADRE Plant Matrix Database

    DEFF Research Database (Denmark)

    2014-01-01

    COMPADRE contains demographic information on hundreds of plant species. The data in COMPADRE are in the form of matrix population models and our goal is to make these publicly available to facilitate their use for research and teaching purposes. COMPADRE is an open-access database. We only request...

  19. REPLIKASI UNIDIRECTIONAL PADA HETEROGEN DATABASE

    Directory of Open Access Journals (Sweden)

    Hendro Nindito

    2013-11-01

    where development can be done quickly and testing of working models of the interaction process is done through repeated. From this research it is obtained that the database replication technology using Oracle Golden Gate can be applied in heterogeneous environments in real time as well.

  20. The COMPADRE Plant Matrix Database

    DEFF Research Database (Denmark)

    2014-01-01

    COMPADRE contains demographic information on hundreds of plant species. The data in COMPADRE are in the form of matrix population models and our goal is to make these publicly available to facilitate their use for research and teaching purposes. COMPADRE is an open-access database. We only request...