Language Choice and Use of Malaysian Public University Lecturers in the Education Domain

Directory of Open Access Journals (Sweden)

Tam Lee Mei

2016-02-01

Full Text Available It is a norm for people from a multilingual and multicultural country such as Malaysia to speak at least two or more languages. Thus, the Malaysian multilingual situation resulted in speakers having to make decisions about which languages are to be used for different purposes in different domains. In order to explain the phenomenon of language choice, Fishman domain analysis (1964 was adapted into this research. According to Fishman’s domain analysis, language choice and use may depend on the speaker’s experiences situated in different settings, different language repertoires that are available to the speaker, different interlocutors and different topics. Such situations inevitably cause barriers and difficulties to those professionals who work in the education domain. Therefore, the purpose of this research is to explore the language choice and use of Malaysian public university lecturers in the education domain and to investigate whether any significant differences exist between ethnicity and field of study with the English language choice and use of the lecturers. 200 survey questionnaires were distributed to examine the details of the lecturers’ language choice and use. The findings of this research reveal that all of the respondents generally preferred to choose and use English language in both formal and informal education domain. Besides, all of the respondents claimed that they chose and used more than one language. It is also found that ethnicity and field of study of the respondents influence the language choice and use in the education domain. In addition, this research suggested that the language and educational policy makers have been largely successful in raising the role and status of the English language as the medium of instruction in tertiary education while maintaining the Malay language as having an important role in the communicative acts, thus characterizing the lecturers’ language choice and use. Keywords: Language

End States, Ladder Compounds, and Domain-Wall Fermions

International Nuclear Information System (INIS)

Creutz, M.

1999-01-01

A magnetic field applied to a cross-linked ladder compound can generate isolated electronic states bound to the ends of the chain. After exploring the interference phenomena responsible, I discuss a connection to the domain-wall approach to chiral fermions in lattice gauge theory. The robust nature of the states under small variations of the bond strengths is tied to chiral symmetry and the multiplicative renormalization of fermion masses. copyright 1999 The American Physical Society

The effects of public health policies on population health and health inequalities in European welfare states: protocol for an umbrella review.

Science.gov (United States)

Thomson, Katie; Bambra, Clare; McNamara, Courtney; Huijts, Tim; Todd, Adam

2016-04-08

The welfare state is potentially an important macro-level determinant of health that also moderates the extent, and impact, of socio-economic inequalities in exposure to the social determinants of health. The welfare state has three main policy domains: health care, social policy (e.g. social transfers and education) and public health policy. This is the protocol for an umbrella review to examine the latter; its aim is to assess how European welfare states influence the social determinants of health inequalities institutionally through public health policies. A systematic review methodology will be used to identify systematic reviews from high-income countries (including additional EU-28 members) that describe the health and health equity effects of upstream public health interventions. Interventions will focus on primary and secondary prevention policies including fiscal measures, regulation, education, preventative treatment and screening across ten public health domains (tobacco; alcohol; food and nutrition; reproductive health services; the control of infectious diseases; screening; mental health; road traffic injuries; air, land and water pollution; and workplace regulations). Twenty databases will be searched using a pre-determined search strategy to evaluate population-level public health interventions. Understanding the impact of specific public health policy interventions will help to establish causality in terms of the effects of welfare states on population health and health inequalities. The review will document contextual information on how population-level public health interventions are organised, implemented and delivered. This information can be used to identify effective interventions that could be implemented to reduce health inequalities between and within European countries. PROSPERO CRD42016025283.

New Inversion and Interpretation of Public-Domain Electromagnetic Survey Data from Selected Areas in Alaska

Science.gov (United States)

Smith, B. D.; Kass, A.; Saltus, R. W.; Minsley, B. J.; Deszcz-Pan, M.; Bloss, B. R.; Burns, L. E.

2013-12-01

Public-domain airborne geophysical surveys (combined electromagnetics and magnetics), mostly collected for and released by the State of Alaska, Division of Geological and Geophysical Surveys (DGGS), are a unique and valuable resource for both geologic interpretation and geophysical methods development. A new joint effort by the US Geological Survey (USGS) and the DGGS aims to add value to these data through the application of novel advanced inversion methods and through innovative and intuitive display of data: maps, profiles, voxel-based models, and displays of estimated inversion quality and confidence. Our goal is to make these data even more valuable for interpretation of geologic frameworks, geotechnical studies, and cryosphere studies, by producing robust estimates of subsurface resistivity that can be used by non-geophysicists. The available datasets, which are available in the public domain, include 39 frequency-domain electromagnetic datasets collected since 1993, and continue to grow with 5 more data releases pending in 2013. The majority of these datasets were flown for mineral resource purposes, with one survey designed for infrastructure analysis. In addition, several USGS datasets are included in this study. The USGS has recently developed new inversion methodologies for airborne EM data and have begun to apply these and other new techniques to the available datasets. These include a trans-dimensional Markov Chain Monte Carlo technique, laterally-constrained regularized inversions, and deterministic inversions which include calibration factors as a free parameter. Incorporation of the magnetic data as an additional constraining dataset has also improved the inversion results. Processing has been completed in several areas, including Fortymile and the Alaska Highway surveys, and continues in others such as the Styx River and Nome surveys. Utilizing these new techniques, we provide models beyond the apparent resistivity maps supplied by the original

Blockchain-based Public Key Infrastructure for Inter-Domain Secure Routing

OpenAIRE

de la Rocha Gómez-Arevalillo , Alfonso; Papadimitratos , Panos

2017-01-01

International audience; A gamut of secure inter-domain routing protocols has been proposed in the literature. They use traditional PGP-like and centralized Public Key Infrastructures for trust management. In this paper, we propose our alternative approach for managing security associations, Secure Blockchain Trust Management (SBTM), a trust management system that instantiates a blockchain-based PKI for the operation of securerouting protocols. A main motivation for SBTM is to facilitate gradu...

Remotely Piloted Aircraft and War in the Public Relations Domain

Science.gov (United States)

2014-10-01

the terms as they appear in quoted texts. 2. Peter Kreeft, Socratic Logic: A Logic Text Using Socratic Method , Platonic Questions, and Aristotelian...Ronald Brooks.22 This method of refuting an argu- ment reflects option C (above), demonstrating that the conclusion does not follow from the premises...and War in the Public Relations Domain Feature tional Security Assistance Force (ISAF) met to discuss methods of elim- inating civilian casualties in

Public health insurance under a nonbenevolent state.

Science.gov (United States)

Lemieux, Pierre

2008-10-01

This paper explores the consequences of the oft ignored fact that public health insurance must actually be supplied by the state. Depending how the state is modeled, different health insurance outcomes are expected. The benevolent model of the state does not account for many actual features of public health insurance systems. One alternative is to use a standard public choice model, where state action is determined by interaction between self-interested actors. Another alternative--related to a strand in public choice theory--is to model the state as Leviathan. Interestingly, some proponents of public health insurance use an implicit Leviathan model, but not consistently. The Leviathan model of the state explains many features of public health insurance: its uncontrolled growth, its tendency toward monopoly, its capacity to buy trust and loyalty from the common people, its surveillance ability, its controlling nature, and even the persistence of its inefficiencies and waiting lines.

Structural Characterization of Monomeric/Dimeric State of p59fyn SH2 Domain.

Science.gov (United States)

Huculeci, Radu; Kieken, Fabien; Garcia-Pino, Abel; Buts, Lieven; van Nuland, Nico; Lenaerts, Tom

2017-01-01

Src homology 2 (SH2) domains are key modulators in various signaling pathways allowing the recognition of phosphotyrosine sites of different proteins. Despite the fact that SH2 domains acquire their biological functions in a monomeric state, a multitude of reports have shown their tendency to dimerize. Here, we provide a technical description on how to isolate and characterize by gel filtration, circular dichroism (CD), and nuclear magnetic resonance (NMR) each conformational state of p59 fyn SH2 domain.

Climiate Resilience Screening Index and Domain Scores

Data.gov (United States)

U.S. Environmental Protection Agency — CRSI and related-domain scores for all 50 states and 3135 counties in the U.S. This dataset is not publicly accessible because: They are already available within the...

Application of modern tensor calculus to engineered domain structures. 2. Tensor distinction of domain states

Czech Academy of Sciences Publication Activity Database

Kopský, Vojtěch

2006-01-01

Roč. 62, - (2006), s. 65-76 ISSN 0108-7673 R&D Projects: GA ČR GA202/04/0992 Institutional research plan: CEZ:AV0Z10100520 Keywords : tensorial covariants * domain states * stability spaces Subject RIV: BE - Theoretical Physics Impact factor: 1.676, year: 2006

Edge states in gated bilayer-monolayer graphene ribbons and bilayer domain walls

Science.gov (United States)

Mirzakhani, M.; Zarenia, M.; Peeters, F. M.

2018-05-01

Using the effective continuum model, the electron energy spectrum of gated bilayer graphene with a step-like region of decoupled graphene layers at the edge of the sample is studied. Different types of coupled-decoupled interfaces are considered, i.e., zigzag (ZZ) and armchair junctions, which result in significant different propagating states. Two non-valley-polarized conducting edge states are observed for ZZ type, which are mainly located around the ZZ-ended graphene layers. Additionally, we investigated both BA-BA and BA-AB domain walls in the gated bilayer graphene within the continuum approximation. Unlike the BA-BA domain wall, which exhibits gapped insulating behaviour, the domain walls surrounded by different stackings of bilayer regions feature valley-polarized edge states. Our findings are consistent with other theoretical calculations, such as from the tight-binding model and first-principles calculations, and agree with experimental observations.

Suburban development – a search for public domains in Danish suburban neighbourhoods

DEFF Research Database (Denmark)

Melgaard, Bente; Bech-Danielsen, Claus

These years some of the post-war Danish suburbs are facing great challenges – social segregation, demographic changes and challenges in building technology. In particular, segregation prevents social life from unfolding across social, economic and cultural borders. Therefore, in this paper......, potentials for bridge-building across the enclaves of the suburb are looked for through a combined architectural-anthropological mapping of public spaces in a specific suburb in Denmark, the analyses being carried out in the light of Hajer & Reijndorp’s definition of public domains and the term exchange...

Diverse oligomeric states of CEACAM IgV domains.

Science.gov (United States)

Bonsor, Daniel A; Günther, Sebastian; Beadenkopf, Robert; Beckett, Dorothy; Sundberg, Eric J

2015-11-03

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) comprise a large family of cell surface adhesion molecules that bind to themselves and other family members to carry out numerous cellular functions, including proliferation, signaling, differentiation, tumor suppression, and survival. They also play diverse and significant roles in immunity and infection. The formation of CEACAM oligomers is caused predominantly by interactions between their N-terminal IgV domains. Although X-ray crystal structures of CEACAM IgV domain homodimers have been described, how CEACAMs form heterodimers or remain monomers is poorly understood. To address this key aspect of CEACAM function, we determined the crystal structures of IgV domains that form a homodimeric CEACAM6 complex, monomeric CEACAM8, and a heterodimeric CEACAM6-CEACAM8 complex. To confirm and quantify these interactions in solution, we used analytical ultracentrifugation to measure the dimerization constants of CEACAM homodimers and isothermal titration calorimetry to determine the thermodynamic parameters and binding affinities of CEACAM heterodimers. We found the CEACAM6-CEACAM8 heterodimeric state to be substantially favored energetically relative to the CEACAM6 homodimer. Our data provide a molecular basis for the adoption of the diverse oligomeric states known to exist for CEACAMs and suggest ways in which CEACAM6 and CEACAM8 regulate the biological functions of one another, as well as of additional CEACAMs with which they interact, both in cis and in trans.

The Value of Privacy and Surveillance Drones in the Public Domain : Scrutinizing the Dutch Flexible Deployment of Mobile Cameras Act

NARCIS (Netherlands)

Gerdo Kuiper; Quirine Eijkman

2017-01-01

The flexible deployment of drones in the public domain, is in this article assessed from a legal philosophical perspective. On the basis of theories of Dworkin and Moore the distinction between individual rights and collective security policy goals is discussed. Mobile cameras in the public domain

Agents unleashed a public domain look at agent technology

CERN Document Server

Wayner, Peter

1995-01-01

Agents Unleashed: A Public Domain Look at Agent Technology covers details of building a secure agent realm. The book discusses the technology for creating seamlessly integrated networks that allow programs to move from machine to machine without leaving a trail of havoc; as well as the technical details of how an agent will move through the network, prove its identity, and execute its code without endangering the host. The text also describes the organization of the host's work processing an agent; error messages, bad agent expulsion, and errors in XLISP-agents; and the simulators of errors, f

The International River Interface Cooperative: Public Domain Software for River Flow and Morphodynamics (Invited)

Science.gov (United States)

Nelson, J. M.; Shimizu, Y.; McDonald, R.; Takebayashi, H.

2009-12-01

The International River Interface Cooperative is an informal organization made up of academic faculty and government scientists with the goal of developing, distributing and providing education for a public-domain software interface for modeling river flow and morphodynamics. Formed in late 2007, the group released the first version of this interface (iRIC) in late 2009. iRIC includes models for two and three-dimensional flow, sediment transport, bed evolution, groundwater-surface water interaction, topographic data processing, and habitat assessment, as well as comprehensive data and model output visualization, mapping, and editing tools. All the tools in iRIC are specifically designed for use in river reaches and utilize common river data sets. The models are couched within a single graphical user interface so that a broad spectrum of models are available to users without learning new pre- and post-processing tools. The first version of iRIC was developed by combining the USGS public-domain Multi-Dimensional Surface Water Modeling System (MD_SWMS), developed at the USGS Geomorphology and Sediment Transport Laboratory in Golden, Colorado, with the public-domain river modeling code NAYS developed by the Universities of Hokkaido and Kyoto, Mizuho Corporation, and the Foundation of the River Disaster Prevention Research Institute in Sapporo, Japan. Since this initial effort, other Universities and Agencies have joined the group, and the interface has been expanded to allow users to integrate their own modeling code using Executable Markup Language (XML), which provides easy access and expandability to the iRIC software interface. In this presentation, the current components of iRIC are described and results from several practical modeling applications are presented to illustrate the capabilities and flexibility of the software. In addition, some future extensions to iRIC are demonstrated, including software for Lagrangian particle tracking and the prediction of

The history and use of cancer registry data by public health cancer control programs in the United States.

Science.gov (United States)

White, Mary C; Babcock, Frances; Hayes, Nikki S; Mariotto, Angela B; Wong, Faye L; Kohler, Betsy A; Weir, Hannah K

2017-12-15

Because cancer registry data provide a census of cancer cases, registry data can be used to: 1) define and monitor cancer incidence at the local, state, and national levels; 2) investigate patterns of cancer treatment; and 3) evaluate the effectiveness of public health efforts to prevent cancer cases and improve cancer survival. The purpose of this article is to provide a broad overview of the history of cancer surveillance programs in the United States, and illustrate the expanding ways in which cancer surveillance data are being made available and contributing to cancer control programs. The article describes the building of the cancer registry infrastructure and the successful coordination of efforts among the 2 federal agencies that support cancer registry programs, the Centers for Disease Control and Prevention and the National Cancer Institute, and the North American Association of Central Cancer Registries. The major US cancer control programs also are described, including the National Comprehensive Cancer Control Program, the National Breast and Cervical Cancer Early Detection Program, and the Colorectal Cancer Control Program. This overview illustrates how cancer registry data can inform public health actions to reduce disparities in cancer outcomes and may be instructional for a variety of cancer control professionals in the United States and in other countries. Cancer 2017;123:4969-76. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

Public-domain software for root image analysis

Directory of Open Access Journals (Sweden)

Mirian Cristina Gomes Costa

2014-10-01

Full Text Available In the search for high efficiency in root studies, computational systems have been developed to analyze digital images. ImageJ and Safira are public-domain systems that may be used for image analysis of washed roots. However, differences in root properties measured using ImageJ and Safira are supposed. This study compared values of root length and surface area obtained with public-domain systems with values obtained by a reference method. Root samples were collected in a banana plantation in an area of a shallower Typic Carbonatic Haplic Cambisol (CXk, and an area of a deeper Typic Haplic Ta Eutrophic Cambisol (CXve, at six depths in five replications. Root images were digitized and the systems ImageJ and Safira used to determine root length and surface area. The line-intersect method modified by Tennant was used as reference; values of root length and surface area measured with the different systems were analyzed by Pearson's correlation coefficient and compared by the confidence interval and t-test. Both systems ImageJ and Safira had positive correlation coefficients with the reference method for root length and surface area data in CXk and CXve. The correlation coefficient ranged from 0.54 to 0.80, with lowest value observed for ImageJ in the measurement of surface area of roots sampled in CXve. The IC (95 % revealed that root length measurements with Safira did not differ from that with the reference method in CXk (-77.3 to 244.0 mm. Regarding surface area measurements, Safira did not differ from the reference method for samples collected in CXk (-530.6 to 565.8 mm² as well as in CXve (-4231 to 612.1 mm². However, measurements with ImageJ were different from those obtained by the reference method, underestimating length and surface area in samples collected in CXk and CXve. Both ImageJ and Safira allow an identification of increases or decreases in root length and surface area. However, Safira results for root length and surface area are

DATABASES AND THE SUI-GENERIS RIGHT – PROTECTION OUTSIDE THE ORIGINALITY. THE DISREGARD OF THE PUBLIC DOMAIN

Directory of Open Access Journals (Sweden)

Monica LUPAȘCU

2018-05-01

Full Text Available This study focuses on databases as they are regulated by Directive no.96/9/EC regarding the protection of databases. There are also several references to Romanian Law no.8/1996 on copyright and neighbouring rights which implements the mentioned European Directive. The study analyses certain effects that the sui-generis protection has on public domain. The study tries to demonstrate that the reglementation specific to databases neglects the interests correlated with the public domain. The effect of such a regulation is the abusive creation of some databases in which the public domain (meaning information not protected by copyright such as news, ideas, procedures, methods, systems, processes, concepts, principles, discoveries ends up being encapsulated and made available only to some private interests, the access to public domain being regulated indirectly. The study begins by explaining the sui- generis right and its origin. The first mention of databases can be found in “Green Paper on Copyright (1998,” a document that clearly shows, the database protection was thought to cover a sphere of information non-protectable from the scientific and industrial fields. Several arguments are made by the author, most of them based on the report of the Public Consultation sustained in 2014 in regards to the necessity of the sui-generis right. There are some references made to a specific case law, namely British Houseracing Board vs William Hill and Fixture Marketing Ldt. The ECJ’s decision în that case is of great importance for the support of public interest to access information corresponding to some restrictive fields that are derived as a result of the maker’s activities, because in the absence of the sui-generis right, all this information can be freely accessed and used.

Magnetic vortex state and multi-domain pattern in electrodeposited hemispherical nanogranular nickel films

International Nuclear Information System (INIS)

Samardak, Alexander; Sukovatitsina, Ekaterina; Ognev, Alexey; Stebliy, Maksim; Davydenko, Alexander; Chebotkevich, Ludmila; Keun Kim, Young; Nasirpouri, Forough; Janjan, Seyed-Mehdi; Nasirpouri, Farzad

2014-01-01

Magnetic states of nickel nanogranular films were studied in two distinct structures of individual and agglomerated granules electrodeposited on n-type Si(1 1 1) surface from a modified Watts bath at a low pH of 2. Magnetic force microscopy and micromagnetic simulations revealed three-dimensional out-of-plane magnetic vortex states in stand-alone hemispherical granules and their arrays, and multi-domain patterns in large agglomerates and integrated films. Once the granules coalesce into small chains or clusters, the coercivity values increased due to the reduction of inter-granular spacing and strengthening of the magnetostatic interaction. Further growth leads to the formation of a continuous granulated film which strongly affected the coercivity and remanence. This was characterized by the domain wall nucleation and propagation leading to a stripe domain pattern. Magnetoresistance measurements as a function of external magnetic field are indicative of anisotropic magnetoresistance (AMR) for the continuous films electrodeposited on Si substrate. - Highlights: • Magnetic states of electrodeposited nickel in isolated spherical and agglomerated nanogranules, and a continuous film. • Preferential magnetization reversal mechanism in isolated granules is vortex state. • Micromagnetic simulations confirm the three-dimensional vortex. • Transition between the vortex state and multi-domain magnetic pattern causes a significant decrease in the coercive force. • Continuous nickel films electrodeposited on silicon substrate exhibit AMR whose magnitude increases with the film thickness

Basement domain map of the conterminous United States and Alaska

Science.gov (United States)

Lund, Karen; Box, Stephen E.; Holm-Denoma, Christopher S.; San Juan, Carma A.; Blakely, Richard J.; Saltus, Richard W.; Anderson, Eric D.; DeWitt, Ed

2015-01-01

The basement-domain map is a compilation of basement domains in the conterminous United States and Alaska designed to be used at 1:5,000,000-scale, particularly as a base layer for national-scale mineral resource assessments. Seventy-seven basement domains are represented as eighty-three polygons on the map. The domains are based on interpretations of basement composition, origin, and architecture and developed from a variety of sources. Analysis of previously published basement, lithotectonic, and terrane maps as well as models of planetary development were used to formulate the concept of basement and the methodology of defining domains that spanned the ages of Archean to present but formed through different processes. The preliminary compilations for the study areas utilized these maps, national-scale gravity and aeromagnetic data, published and limited new age and isotopic data, limited new field investigations, and conventional geologic maps. Citation of the relevant source data for compilations and the source and types of original interpretation, as derived from different types of data, are provided in supporting descriptive text and tables.

Publication List - New York State Museum.

Science.gov (United States)

New York State Museum, Albany.

Presented is a list of publications in six areas: (1) Anthropology and Archeology, (2) Botany, (3) Entomology, (4) Zoology, (5) Geology and Paleontology, and (6) Miscellaneous. This list was produced by the New York State Department of Education in cooperation with the New York State Museum. The list includes the publication number, author(s),…

Public health nursing competency in a rural/frontier state.

Science.gov (United States)

Bigbee, Jeri L; Otterness, Nancy; Gehrke, Pam

2010-01-01

To assess the self-reported levels of competency among public health nurses (PHNs) in Idaho. A cross-sectional descriptive design was used. The sample consisted of 124 PHNs, including 30 in leadership roles, currently practicing in Idaho's official public health agencies. Structured interviews were conducted with participants who provided self-ratings in the 8 domains of public health competency as developed by the Council on Linkages Between Academia and Public Health Practice and the Quad Council of Public Health Nursing Organizations. The findings indicated that the overall level of competency was most strongly associated with the duration of professional experience. No major differences in the competency levels were found in relation to nurses' level of education or licensure. Nurses in leadership positions reported the highest levels of competency. Rurality, as measured by district population density, was not significantly correlated with competency levels, except in relation to community dimensions of practice skills. The findings suggest that PHNs' self-perceived levels of competence are most strongly influenced by their years of professional experience, particularly in leadership roles. Professional development efforts should focus on the domains with the lowest perceived competency: policy development/program planning skills, analytic assessment skills, and financial planning/management skills.

Combating Identity Fraud in the Public Domain: Information Strategies for Healthcare and Criminal Justice

NARCIS (Netherlands)

Plomp, M.G.A.; Grijpink, J.H.A.M.

2011-01-01

Two trends are present in both the private and public domain: increasing interorganisational co-operation and increasing digitisation. Nowadays, more and more processes within and between organisations take place electronically. These developments are visible on local, national and European scale.

State commitment to public participation

International Nuclear Information System (INIS)

Baranski, S.C.; Serie, P.J.

1989-01-01

This paper discusses how New York's approach to developing a new low-level radioactive waste disposal facility demonstrates a commitment to responsibility for waste generated within its borders. There is a strong, legislated commitment to meeting federal milestones and starting from scratch to select a suitable site and disposal method. Equally strong is the state's commitment to meaningful public participation. A statewide program is underway, including public information and education and interactive techniques. The public participation program is fully integrated with the technical and policy activities of the New York State Low-Level Radioactive Waste Siting Commission at all levels. The program is designed to progressively tailor techniques and coverage to the steps in site and method selection, and will focus most intensively on the communities where four sites are selected for full characterization

Survey of state funding for public transportation 2010

Science.gov (United States)

2010-07-01

The AASHTO Standing Committee on Public Transportation is pleased to release the Survey of State : Funding for Public Transportation. The survey results reflect Fiscal Year 2008 data. This annual report : provides a snapshot of state-by-state investm...

Public Health Implications of Changing Rodent Importation Patterns - United States, 1999-2013.

Science.gov (United States)

Lankau, E W; Sinclair, J R; Schroeder, B A; Galland, G G; Marano, N

2017-04-01

The United States imports a large volume of live wild and domestic animal species; these animals pose a demonstrated risk for introduction of zoonotic diseases. Rodents are imported for multiple purposes, including scientific research, zoo exhibits and the pet trade. Current U.S. public health regulatory restrictions specific to rodent importation pertain only to those of African origin. To understand the impacts of these regulations and the potential public health risks of international rodent trade to the United States, we evaluated live rodent import records during 1999-2013 by shipment volume and geographic origin, source (e.g. wild-caught versus captive- or commercially bred), intended purpose and rodent taxonomy. Live rodent imports increased from 2737 animals during 1999 to 173 761 animals during 2013. Increases in both the number and size of shipments contributed to this trend. The proportion of wild-captured imports declined from 75% during 1999 to guinea pigs and hamsters arriving from other countries in North America were predominant taxa underlying this trend. After 2003, African-origin imports became sporadic events under the federal permit process. These patterns suggest development of large-scale captive rodent breeding markets abroad for commercial sale in the United States. While the shift from wild-captured imports alleviates many conservation concerns and risks for novel disease emergence, such consolidated sourcing might elevate exposure risks for zoonotic diseases associated with high-density rodent breeding (e.g. lymphocytic choriomeningitis or salmonellosis). A responsive border health system must periodically re-evaluate importation regulations in conjunction with key stakeholders to ensure a balance between the economic benefits of rodent trade against the potential public health risks. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.

Alaska Public Offices Commission, Department of Administration, State of

Science.gov (United States)

Visiting Alaska State Employees State of Alaska Department of Administration Alaska Public Offices Commission Alaska Department of Administration, Alaska Public Offices Commission APOC Home Commission Filer ; AO's Contact Us Administration > Alaska Public Offices Commission Alaska Public Offices Commission

Home, Office of Public Advocacy, Department of Administration, State of

Science.gov (United States)

Visiting Alaska State Employees State of Alaska Department of Administration Division of Office of Public Advocacy Alaska Department of Administration, Office of Public Advocacy Home Programs Sections Forms Vendor Support Search Office of Public Advocacy State of Alaska Administration > Office of Public Advocacy

State funding for local public health: observations from six case studies.

Science.gov (United States)

Potter, Margaret A; Fitzpatrick, Tiffany

2007-01-01

The purpose of this study is to describe state funding of local public health within the context of state public health system types. These types are based on administrative relationships, legal structures, and relative proportion of state funding in local public health budgets. We selected six states representing various types and geographic regions. A case study for each state summarized available information and was validated by state public health officials. An analysis of the case studies reveals that the variability of state public health systems--even within a given type--is matched by variability in approaches to funding local public health. Nevertheless, some meaningful associations appear. For example, higher proportions of state funding occur along with higher levels of state oversight and the existence of local service mandates in state law. These associations suggest topics for future research on public health financing in relation to local accountability, local input to state priority-setting, mandated local services, and the absence of state funds for public health services in some local jurisdictions.

Aviation and Airports, Transportation & Public Facilities, State of Alaska

Science.gov (United States)

State Employees Alaska Department of Transportation & Public Facilities header image Alaska Department of Transportation & Public Facilities / Aviation and Airports Search DOT&PF State of pages view official DOT&PF Flickr pages Department of Transportation & Public Facilities PO Box

Inhomogeneous states of nonequilibrium superconductors: Quasiparticle bags and antiphase domain walls

International Nuclear Information System (INIS)

Salkola, M.I.; Schrieffer, J.R.

1998-01-01

Nonequilibrium properties of short-coherence-length s-wave superconductors are analyzed in the presence of extrinsic and intrinsic inhomogeneities. In general, the lowest-energy configurations of quasiparticle excitations are topological textures into which quasiparticles segregate and that are described as antiphase domain walls between superconducting regions whose order parameter phases differ by π. Antiphase domain walls can be probed by various experimental techniques, for example, by optical absorption and NMR. At zero temperature, quasiparticles seldom appear as self-trapped bag states. However, for low concentrations of quasiparticles, they may be stabilized in superconductors by extrinsic defects. copyright 1998 The American Physical Society

Response to a widespread, unauthorized dispersal of radioactive waste in the public domain

International Nuclear Information System (INIS)

Wenslawski, F.A.; North, H.S.

1979-01-01

In March 1976 State of Nevada radiological health officials became aware that radioactive items destined for disposal at a radioactive waste burial facility near Beatty, Nevada had instead been distributed to wide segments of the public domain. Because the facility was jointly licensed by the State of Nevada and the Federal Nuclear Regulatory Commission, both agencies quickly responded. It was learned that over a period of several years a practice existed at the disposal facility of opening containers, removing contents and allowing employees to take items of worth or fancy. Numerous items such as hand tools, electric motors, laboratory instruments, shipping containers, etc., had received widespread and uncontrolled distribution in the town of Beatty as well as lesser distributions to other locations. Because the situation might have had the potential for a significant health and safety impact, a comprehensive recovery operation was conducted. During the course of seven days of intense effort, thirty-five individuals became involved in a comprehensive door by door survey and search of the town. Aerial surveys were performed using a helicopter equipped with sensitive radiation detectors, while ground level scans were conducted using a van containing similar instrumentation. Aerial reconnaissance photographs were taken, a special town meeting was held and numerous persons were interviewed. The recovery effort resulted in a retrieval of an estimated 20 to 25 pickup truck loads of radioactively contaminated equipment as well as several loads of large items returned on a 40-foot flatbed trailer

Controller design for flexible, distributed parameter mechanical arms via combined state space and frequency domain techniques

Science.gov (United States)

Book, W. J.; Majett, M.

1982-01-01

The potential benefits of the ability to control more flexible mechanical arms are discussed. A justification is made in terms of speed of movement. A new controller design procedure is then developed to provide this capability. It uses both a frequency domain representation and a state variable representation of the arm model. The frequency domain model is used to update the modal state variable model to insure decoupled states. The technique is applied to a simple example with encouraging results.

Fast resolution of the neutron diffusion equation through public domain Ode codes

Energy Technology Data Exchange (ETDEWEB)

Garcia, V.M.; Vidal, V.; Garayoa, J. [Universidad Politecnica de Valencia, Departamento de Sistemas Informaticos, Valencia (Spain); Verdu, G. [Universidad Politecnica de Valencia, Departamento de Ingenieria Quimica y Nuclear, Valencia (Spain); Gomez, R. [I.E.S. de Tavernes Blanques, Valencia (Spain)

2003-07-01

The time-dependent neutron diffusion equation is a partial differential equation with source terms. The resolution method usually includes discretizing the spatial domain, obtaining a large system of linear, stiff ordinary differential equations (ODEs), whose resolution is computationally very expensive. Some standard techniques use a fixed time step to solve the ODE system. This can result in errors (if the time step is too large) or in long computing times (if the time step is too little). To speed up the resolution method, two well-known public domain codes have been selected: DASPK and FCVODE that are powerful codes for the resolution of large systems of stiff ODEs. These codes can estimate the error after each time step, and, depending on this estimation can decide which is the new time step and, possibly, which is the integration method to be used in the next step. With these mechanisms, it is possible to keep the overall error below the chosen tolerances, and, when the system behaves smoothly, to take large time steps increasing the execution speed. In this paper we address the use of the public domain codes DASPK and FCVODE for the resolution of the time-dependent neutron diffusion equation. The efficiency of these codes depends largely on the preconditioning of the big systems of linear equations that must be solved. Several pre-conditioners have been programmed and tested; it was found that the multigrid method is the best of the pre-conditioners tested. Also, it has been found that DASPK has performed better than FCVODE, being more robust for our problem.We can conclude that the use of specialized codes for solving large systems of ODEs can reduce drastically the computational work needed for the solution; and combining them with appropriate pre-conditioners, the reduction can be still more important. It has other crucial advantages, since it allows the user to specify the allowed error, which cannot be done in fixed step implementations; this, of course

.Gov Domains API

Data.gov (United States)

General Services Administration — This dataset offers the list of all .gov domains, including state, local, and tribal .gov domains. It does not include .mil domains, or other federal domains outside...

Procurement and Contracting, Transportation & Public Facilities, State of

Science.gov (United States)

Visiting Alaska State Employees Alaska Department of Transportation & Public Facilities header image Alaska Department of Transportation & Public Facilities / Procurement and Contracting Search DOT& pages Department of Transportation & Public Facilities PO Box 112500 3132 Channel Drive Juneau

Operational Efficiency of Public Transport System in Kwara State ...

African Journals Online (AJOL)

Operational Efficiency of Public Transport System in Kwara State, Nigeria. ... The paper examines the operations of Public Transport in Nigeria using the Kwara State Transport Service as a case study. ... EMAIL FULL TEXT EMAIL FULL TEXT

Report : public transportation in Washington State, 1984

Science.gov (United States)

1984-10-01

This report is an update of the Public Transportation in Washington State publication, dated December 1981. In order to reflect the changes that have occurred since that time, this report contains the most current data obtainable. Chapter One of this...

Time-resolved imaging of domain pattern destruction and recovery via nonequilibrium magnetization states

Science.gov (United States)

Wessels, Philipp; Ewald, Johannes; Wieland, Marek; Nisius, Thomas; Vogel, Andreas; Viefhaus, Jens; Meier, Guido; Wilhein, Thomas; Drescher, Markus

2014-11-01

The destruction and formation of equilibrium multidomain patterns in permalloy (Ni80Fe20 ) microsquares has been captured using pump-probe x-ray magnetic circular dichroism (XMCD) spectromicroscopy at a new full-field magnetic transmission soft x-ray microscopy endstation with subnanosecond time resolution. The movie sequences show the dynamic magnetization response to intense Oersted field pulses of approximately 200-ps root mean square (rms) duration and the magnetization reorganization to the ground-state domain configuration. The measurements display how a vortex flux-closure magnetization distribution emerges out of a nonequilibrium uniform single-domain state. During the destruction of the initial vortex pattern, we have traced the motion of the central vortex core that is ejected out of the microsquare at high velocities exceeding 1 km/s. A reproducible recovery into a defined final vortex state with stable chirality and polarity could be achieved. Using an additional external bias field, the transient reversal of the square magnetization direction could be monitored and consistently reproduced by micromagnetic simulations.

Steady-state configurations of Dzyaloshinskii domain walls driven by field and current

Energy Technology Data Exchange (ETDEWEB)

Sánchez-Tejerina, L., E-mail: luis.st@ee.uva.es [Departamento de Electricidad y Electrónica, Facultad de Ciencias, Universidad de Valladolid, 47011 Valladolid (Spain); Departamento de Física Aplicada, Facultad de Ciencias, Universidad de Salamanca, 37011 Salamanca (Spain); Alejos, O. [Departamento de Electricidad y Electrónica, Facultad de Ciencias, Universidad de Valladolid, 47011 Valladolid (Spain); Martínez, E. [Departamento de Física Aplicada, Facultad de Ciencias, Universidad de Salamanca, 37011 Salamanca (Spain)

2017-02-01

The dynamics of Dzyaloshinskii domain walls (DDW) in ultrathin ferromagnetic strips with perpendicular magnetic anisotropy, for different values of both perpendicular field and longitudinal current excitation associated to the Spin-Hall effect, has been studied, taking into account different values of the interfacial Dzyaloshinskii-Moriya interaction (DMI). This study has been carried out with the help of the q-Φ one-dimensional model and micromagnetic simulations. We have found that Walker breakdown may be avoided by applying a certain threshold current, even though the inverse effect is also possible. We have also found that, for particular values of field and current, the magnetization within the DDW experiences an abrupt change of orientation, which provokes a change on the contribution of current to the terminal DDW velocity. This effect disappears for sufficiently strong DMI, as it is expected from the model. - Highlights: • Steady-state configurations of Dzyaloshinskii domain walls driven by field and current have been reported. • Field-like torques and Slonczewskii-like torques due to spin-orbit interactions have been considered. • The response is associated with the rotation of the domain wall inner magnetization. • An asymmetric behavior arising from the existence of degenerate states is shown. • The asymmetry results in different travelled distances and/or terminal speeds.

Steady-state configurations of Dzyaloshinskii domain walls driven by field and current

International Nuclear Information System (INIS)

Sánchez-Tejerina, L.; Alejos, O.; Martínez, E.

2017-01-01

The dynamics of Dzyaloshinskii domain walls (DDW) in ultrathin ferromagnetic strips with perpendicular magnetic anisotropy, for different values of both perpendicular field and longitudinal current excitation associated to the Spin-Hall effect, has been studied, taking into account different values of the interfacial Dzyaloshinskii-Moriya interaction (DMI). This study has been carried out with the help of the q-Φ one-dimensional model and micromagnetic simulations. We have found that Walker breakdown may be avoided by applying a certain threshold current, even though the inverse effect is also possible. We have also found that, for particular values of field and current, the magnetization within the DDW experiences an abrupt change of orientation, which provokes a change on the contribution of current to the terminal DDW velocity. This effect disappears for sufficiently strong DMI, as it is expected from the model. - Highlights: • Steady-state configurations of Dzyaloshinskii domain walls driven by field and current have been reported. • Field-like torques and Slonczewskii-like torques due to spin-orbit interactions have been considered. • The response is associated with the rotation of the domain wall inner magnetization. • An asymmetric behavior arising from the existence of degenerate states is shown. • The asymmetry results in different travelled distances and/or terminal speeds.

The public understanding of nanotechnology in the food domain: the hidden role of views on science, technology, and nature.

Science.gov (United States)

Vandermoere, Frederic; Blanchemanche, Sandrine; Bieberstein, Andrea; Marette, Stephan; Roosen, Jutta

2011-03-01

In spite of great expectations about the potential of nanotechnology, this study shows that people are rather ambiguous and pessimistic about nanotechnology applications in the food domain. Our findings are drawn from a survey of public perceptions about nanotechnology food and nanotechnology food packaging (N = 752). Multinomial logistic regression analyses further reveal that knowledge about food risks and nanotechnology significantly influences people's views about nanotechnology food packaging. However, knowledge variables were unrelated to support for nanofood, suggesting that an increase in people's knowledge might not be sufficient to bridge the gap between the excitement some business leaders in the food sector have and the restraint of the public. Additionally, opposition to nanofood was not related to the use of heuristics but to trust in governmental agencies. Furthermore, the results indicate that public perceptions of nanoscience in the food domain significantly relate to views on science, technology, and nature.

Geothermal publications list for Geopowering the West States

Energy Technology Data Exchange (ETDEWEB)

None

2004-12-01

A list of geothermal publications is provided for each of the states under the ''GeoPowering the West'' program. They are provided to assist the various states in developing their geothermal resources for direct-use and electric power applications. Each state publication list includes the following: (1) General papers on various direct-uses and electric power generation available from the Geo-Heat Center either by mail or on-line at: http://geoheat.oit.edu. (2) General Geo-Heat Center Quarterly Bulletin articles related to various geothermal uses--also available either by mail or on-line; (3) Publications from other web sites such as: Geothermal-Biz.com; NREL, EGI, GEO and others ; and (4) Geothermal Resources Council citations, which are available from their web site: www.geothermal.org.

A Fast, Efficient Domain Adaptation Technique for Cross-Domain Electroencephalography(EEG-Based Emotion Recognition

Directory of Open Access Journals (Sweden)

Xin Chai

2017-05-01

Full Text Available Electroencephalography (EEG-based emotion recognition is an important element in psychiatric health diagnosis for patients. However, the underlying EEG sensor signals are always non-stationary if they are sampled from different experimental sessions or subjects. This results in the deterioration of the classification performance. Domain adaptation methods offer an effective way to reduce the discrepancy of marginal distribution. However, for EEG sensor signals, both marginal and conditional distributions may be mismatched. In addition, the existing domain adaptation strategies always require a high level of additional computation. To address this problem, a novel strategy named adaptive subspace feature matching (ASFM is proposed in this paper in order to integrate both the marginal and conditional distributions within a unified framework (without any labeled samples from target subjects. Specifically, we develop a linear transformation function which matches the marginal distributions of the source and target subspaces without a regularization term. This significantly decreases the time complexity of our domain adaptation procedure. As a result, both marginal and conditional distribution discrepancies between the source domain and unlabeled target domain can be reduced, and logistic regression (LR can be applied to the new source domain in order to train a classifier for use in the target domain, since the aligned source domain follows a distribution which is similar to that of the target domain. We compare our ASFM method with six typical approaches using a public EEG dataset with three affective states: positive, neutral, and negative. Both offline and online evaluations were performed. The subject-to-subject offline experimental results demonstrate that our component achieves a mean accuracy and standard deviation of 80.46% and 6.84%, respectively, as compared with a state-of-the-art method, the subspace alignment auto-encoder (SAAE, which

[On the role of the state-private partnership in public health].

Science.gov (United States)

Nechaev, V S; Nisan, B A

2012-01-01

The article deals with the issues of study of state-private partnership in the framework of development of strategic measures of regulation of this area in public health. It is demonstrated that the regulation of state-private partnership has to combine the dynamism inherent in entrepreneurship and the public stability needed for normal public health functioning. The control functions of state authorities in the area of public health policy developed into concept of "supervision" which obligates the state to manage the health system guided by norms of ethics and financial expediency. The regulation as a main tool of "supervision" in the state-private partnership has to meet the same two requirements. The activation of entrepreneur activity in public health by no means is caused by increase of privatization in this sector. Under these conditions, the implementation of market mechanisms in public health system make is more effective and efficient.

Towards an information strategy for combating identity fraud in the public domain: Cases from healthcare and criminal justice

NARCIS (Netherlands)

Plomp, M.G.A.; Grijpink, J.H.A.M.

2011-01-01

Two trends are present in both the private and public domain: increasing interorganisational co-operation and increasing digitisation. More and more processes within and between organisations take place electronically, on local, national and European scale. The technological and organisational

Between-Domain Relations of Students’ Academic Emotions and Their Judgments of School Domain Similarity

Directory of Open Access Journals (Sweden)

Thomas eGoetz

2014-10-01

Full Text Available With the aim to deepen our understanding of the between-domain relations of academic emotions, a series of three studies was conducted. We theorized that between-domain relations of trait (i.e., habitual emotions reflected students’ judgments of domain similarities, whereas between-domain relations of state (i.e., momentary emotions did not. This supposition was based on the accessibility model of emotional self-report, according to which individuals’ beliefs tend to strongly impact trait, but not state emotions. The aim of Study 1 (interviews; N = 40; 8th and 11th graders was to gather salient characteristics of academic domains from students’ perspective. In Study 2 (N=1709; 8th and 11th graders the 13 characteristics identified in Study 1 were assessed along with academic emotions in four different domains (mathematics, physics, German, and English using a questionnaire-based trait assessment. With respect to the same domains, state emotions were assessed in Study 3 (N = 121; 8th and 11th graders by employing an experience sampling approach. In line with our initial assumptions, between-domain relations of trait but not state academic emotions reflected between-domain relations of domain characteristics. Implications for research and practice are discussed.

Between-domain relations of students' academic emotions and their judgments of school domain similarity

Science.gov (United States)

Goetz, Thomas; Haag, Ludwig; Lipnevich, Anastasiya A.; Keller, Melanie M.; Frenzel, Anne C.; Collier, Antonie P. M.

2014-01-01

With the aim to deepen our understanding of the between-domain relations of academic emotions, a series of three studies was conducted. We theorized that between-domain relations of trait (i.e., habitual) emotions reflected students' judgments of domain similarities, whereas between-domain relations of state (i.e., momentary) emotions did not. This supposition was based on the accessibility model of emotional self-report, according to which individuals' beliefs tend to strongly impact trait, but not state emotions. The aim of Study 1 (interviews; N = 40; 8th and 11th graders) was to gather salient characteristics of academic domains from students' perspective. In Study 2 (N = 1709; 8th and 11th graders) the 13 characteristics identified in Study 1 were assessed along with academic emotions in four different domains (mathematics, physics, German, and English) using a questionnaire-based trait assessment. With respect to the same domains, state emotions were assessed in Study 3 (N = 121; 8th and 11th graders) by employing an experience sampling approach. In line with our initial assumptions, between-domain relations of trait but not state academic emotions reflected between-domain relations of domain characteristics. Implications for research and practice are discussed. PMID:25374547

Terrorism and emergency preparedness in state and territorial public health departments--United States, 2004.

Science.gov (United States)

2005-05-13

After the events of September 11, 2001, federal funding for state public health preparedness programs increased from $67 million in fiscal year (FY) 2001 to approximately $1 billion in FY 2002. These funds were intended to support preparedness for and response to terrorism, infectious disease outbreaks, and other public health threats and emergencies. The Council of State and Territorial Epidemiologists (CSTE) assessed the impact of funding on epidemiologic capacity, including terrorism preparedness and response, in state health departments in November 2001 and again in May 2004, after distribution of an additional $1 billion in FY 2003. This report describes the results of those assessments, which indicated that increased funding for terrorism preparedness and emergency response has rapidly increased the number of epidemiologists and increased capacity for preparedness at the state level. However, despite the increase in epidemiologists, state public health officials estimate that 192 additional epidemiologists, an increase of 45.3%, are needed nationwide to fully staff terrorism preparedness programs.

Algorithm for determining two-periodic steady-states in AC machines directly in time domain

Directory of Open Access Journals (Sweden)

Sobczyk Tadeusz J.

2016-09-01

Full Text Available This paper describes an algorithm for finding steady states in AC machines for the cases of their two-periodic nature. The algorithm enables to specify the steady-state solution identified directly in time domain despite of the fact that two-periodic waveforms are not repeated in any finite time interval. The basis for such an algorithm is a discrete differential operator that specifies the temporary values of the derivative of the two-periodic function in the selected set of points on the basis of the values of that function in the same set of points. It allows to develop algebraic equations defining the steady state solution reached in a chosen point set for the nonlinear differential equations describing the AC machines when electrical and mechanical equations should be solved together. That set of those values allows determining the steady state solution at any time instant up to infinity. The algorithm described in this paper is competitive with respect to the one known in literature an approach based on the harmonic balance method operated in frequency domain.

Theoretical and applied aspects of public-state partnership

Directory of Open Access Journals (Sweden)

V. R. Bodelan

2014-10-01

Full Text Available The article summarizes the main approaches to the formation and the development of public-state partnership in foreign countries and in Ukraine. The category «Public-state Partnership» has no clear definition in science, and in public administration it is used in many senses. The lack of theoretical justification, no systematic approach to the separation of theoretical and methodological foundations of the public-state partnerships, the forms of its practical implementation does not allow our country to be competitive internationally. In particular, this applies to such an aspects such as social maturity of business and entrepreneurship. Such companies create NGOs that in many countries provide 3 to 9% of GDP, attract domestic and foreign investments, benefit society and are a form of targeting state impact on the condition and development of social processes and relationships. Ukraine has not yet established the culture of social entrepreneurship, both government authorities and NGOs are not aware how promising such activity authorized by the legislation of Ukraine is. The reserve and the capacity of NGOs when considering formation of a special investment climate, development of production, replenishment of the budgets at all levels, creating conditions for entrepreneurship etc. are not applied. Main role is assigned for the NGOs that make a significant contribution to socio-economic development of the country and become its reliable investment partner.

Advancing public health obesity policy through state attorneys general.

Science.gov (United States)

Pomeranz, Jennifer L; Brownell, Kelly D

2011-03-01

Obesity in the United States exacts a heavy health and financial toll, requiring new approaches to address this public health crisis. State attorneys general have been underutilized in efforts to formulate and implement food and obesity policy solutions. Their authority lies at the intersection of law and public policy, creating unique opportunities unavailable to other officials and government entities. Attorneys general have a broad range of authority over matters specifically relevant to obesity and nutrition policy, including parens patriae (parent of the country) authority, protecting consumer interests, enacting and supporting rules and regulations, working together across states, engaging in consumer education, and drafting opinions and amicus briefs. Significant room exists for greater attorney general involvement in formulating and championing solutions to public health problems such as obesity.

Assessment of current cybersecurity practices in the public domain : cyber indications and warnings domain.

Energy Technology Data Exchange (ETDEWEB)

Hamlet, Jason R.; Keliiaa, Curtis M.

2010-09-01

This report assesses current public domain cyber security practices with respect to cyber indications and warnings. It describes cybersecurity industry and government activities, including cybersecurity tools, methods, practices, and international and government-wide initiatives known to be impacting current practice. Of particular note are the U.S. Government's Trusted Internet Connection (TIC) and 'Einstein' programs, which are serving to consolidate the Government's internet access points and to provide some capability to monitor and mitigate cyber attacks. Next, this report catalogs activities undertaken by various industry and government entities. In addition, it assesses the benchmarks of HPC capability and other HPC attributes that may lend themselves to assist in the solution of this problem. This report draws few conclusions, as it is intended to assess current practice in preparation for future work, however, no explicit references to HPC usage for the purpose of analyzing cyber infrastructure in near-real-time were found in the current practice. This report and a related SAND2010-4766 National Cyber Defense High Performance Computing and Analysis: Concepts, Planning and Roadmap report are intended to provoke discussion throughout a broad audience about developing a cohesive HPC centric solution to wide-area cybersecurity problems.

Public sector leadership: New perspectives for research and practice

OpenAIRE

D. Orazi; A.Turrini; G. Valotti

2013-01-01

In this paper, we aim to portray the state of the art in public sector leadership in order to recommend directions for research and training practice. To this end, we review the scattered strands of literature on public sector leadership (PSL) and classify them in a single framework. The results of the study suggest that public sector leadership is emerging as a distinctive and autonomous domain in public administration/public management studies, although the debate is still underdeveloped co...

Enhancing public access to legal information : A proposal for a new official legal information generic top-level domain

NARCIS (Netherlands)

Mitee, Leesi Ebenezer

2017-01-01

Abstract: This article examines the use of a new legal information generic Top-Level Domain (gTLD) as a viable tool for easy identification of official legal information websites (OLIWs) and enhancing global public access to their resources. This intervention is necessary because of the existence of

Rock Art and Radiance: Archaeology in the Public Domain as Life-Long Learning.

Science.gov (United States)

Ouzman, Sven

The re-invigoration of storytelling in academic and public spheres allows rock art to offer opportunities to various publics, of which archaeologists are part. But how exactly this process of archaeology as lifelong learning is to proceed is not always clear, particularly in the United States. Until the last half decade of the twentieth century,…

Into the Dark Domain: The UK Web Archive as a Source for the Contemporary History of Public Health

Science.gov (United States)

Gorsky, Martin

2015-01-01

With the migration of the written record from paper to digital format, archivists and historians must urgently consider how web content should be conserved, retrieved and analysed. The British Library has recently acquired a large number of UK domain websites, captured 1996–2010, which is colloquially termed the Dark Domain Archive while technical issues surrounding user access are resolved. This article reports the results of an invited pilot project that explores methodological issues surrounding use of this archive. It asks how the relationship between UK public health and local government was represented on the web, drawing on the ‘declinist’ historiography to frame its questions. It points up some difficulties in developing an aggregate picture of web content due to duplication of sites. It also highlights their potential for thematic and discourse analysis, using both text and image, illustrated through an argument about the contradictory rationale for public health policy under New Labour. PMID:26217072

Control of vortex state in cobalt nanorings with domain wall pinning centers

Directory of Open Access Journals (Sweden)

Manohar Lal

2018-05-01

Full Text Available Magnetic rings at the mesoscopic scale exhibit new spin configuration states and switching behavior, which can be controlled via geometrical structure, material composition and applied field. Vortex states in magnetic nanorings ensure flux closure, which is necessary for low stray fields in high packing density in memory devices. We performed magnetoresistance measurements on cobalt nanoring devices and show that by attaching nanowires to the ring, the vortex state can be stabilized. When a square pad is attached to the free end of the wire, the domain wall nucleation field in the nanowire is reduced. In addition, the vortex state persists over a larger range of magnetic fields, and exists at all in-plane orientations of the magnetic field. These experimental findings are well supported by our micromagnetic simulations.

Survey of state funding for public transportation 2005

Science.gov (United States)

2006-05-01

This report is the 25th compilation of information on State funding of public transportation. The transportation departments in all 50 States and the District of Columbia responded to the survey, which was distributed and compiled by the U.S. Departm...

ORD-State Cooperation is Essential to Help States Address Contemporary Environmental Public Health Challenges

Science.gov (United States)

Dr. Cascio’s presentation “ORD-State Cooperation is Essential to Help States Address Contemporary Environmental Public Health Challenges” at ORD’s State Coordination Team Meeting will highlight the role that ORD science and technical expertise in helping t...

Molecular dynamics simulations from putative transition states of alpha-spectrin SH3 domain

NARCIS (Netherlands)

Periole, Xavier; Vendruscolo, Michele; Mark, Alan E.

2007-01-01

A series of molecular dynamics simulations in explicit solvent were started from nine structural models of the transition state of the SH3 domain of alpha-spectrin, which were generated by Lindorff Larsen et al. (Nat Struct Mol Biol 2004;11:443-449) using molecular dynamics simulations in which

Public Libraries and Internet Access across the United States: A Comparison by State 2004–2006

Directory of Open Access Journals (Sweden)

Paul T. Jaeger

2007-06-01

Full Text Available Drawing upon findings from a national survey of U.S. public libraries, this paper examines trends in Internet and public computing access in public libraries across states from 2004 to 2006. Based on library-supplied information about levels and types of Internet and public computing access, the authors offer insights into the network-based content and services that public libraries provide. Examining data from 2004 to 2006 reveals trends and accomplishments in certain states and geographic regions. This paper details and discusses the data, identifies and analyzes issues related to Internet access, and suggests areas for future research.

State-level public policy as a predictor of individual and family well-being.

Science.gov (United States)

Zimmerman, S L

1987-01-01

This exploratory study examines the relationship between state-level public policy and individual and family well-being and factors that affect it. The inquiry, based on exchange and choice theories, assumes that state-level public policy reflects states' awareness of the needs of individuals and families, their ability to predict the future in failing to meet them, and the extent to which the norm of reciprocity prevails in the 50 states. Measures of states' collective choices were states' per capita expenditures for public welfare, education, and health, and per capita taxes in 1980; measures of states' individual and well- or ill-being, or social malaise, were states' teenage birthrates, infant death rates, and suicide rates. Taken into account as antecedent and intervening variables were age, gender, and racial composition, income distribution, marital, socioeconomic, and employment status of states' populations, and attitudes toward public spending. The findings show that higher state expenditures for public welfare and for education indeed contribute to individual and family well-being as measured by lower state rates of suicide and teenage births. States per capita spending for education, which together with state per capita spending for public welfare was a positive predictor of school completion rates and positively associated with states' income level, accounted for almost all of the variance in states' per capita taxes. State spending for public welfare was not a predictor of state per capita taxes. These findings are cause for considerable concern given the reduced role of the federal government in human affairs, particularly in states whose choices violate the assumptions underlying exchange and choice theories and the norm of reciprocity which says that people should help, not hurt, others.

Public Relations in the State Institutions from Galati

Directory of Open Access Journals (Sweden)

Daniela Aurelia Tanase Popa

2016-06-01

Full Text Available The paper aims at identifying and analyzing specific public relations activities in various state institutions from Galati in order to shape a PR typological profile in this geographic area. From the methodological point of view, the paper is based on in-depth interview technique for data collection and content analysis as a method of interpretation. The purpose of this qualitative study is to investigate the professional activity of the specialist in public relations in state institutions in Galati and achieving it was made possible through a structured interview guide on three indicators: professional environment, typological profile, professional responsibility.

THE ECONOMIC CRISIS IMPACT ON PUBLIC EXPENDITURES IN EU NEW MEMBER STATES

Directory of Open Access Journals (Sweden)

Sabau-Popa Diana Claudia

2012-07-01

Full Text Available This article analyzes the main trends of public expenditures in the New Member States 12 in the last decade. We develop a synthetic analysis of the total public expenditures and also an analytical inquiry of major categories of public expenditures according to COFOG. Based on data provided by Eurostat from 2000 to 2010 we try to capture the impact of global financial crisis on the major trends of the public expenditures for new member states. Our purpose is to reveal a global view of the state of public expenditures in this group of EU countries and also we try to make a comparison between Romania and these countries considering that the stance of public finance is quite similar to the new member states. The major findings of this study are the high increase of the public expenditures for all the countries especially in 2009, due to a huge increase of the social protection expenditures. In this context we underline some correlations between the public expenditures evolution and economic growth.

Capitalism and Public Education in the United States

Science.gov (United States)

Schneller, Peter L.

2017-01-01

The United States democratic system includes characteristics of capitalism as well as socialism. Perhaps the most socialistic endeavor of the US is its K-12 public school system; in fact, US public schools are necessary for democracy to thrive and to create an educated and well-informed populace. However, capitalism and socialism are strange…

Transient intermediates are populated in the folding pathways of single-domain two-state folding protein L

Science.gov (United States)

Maity, Hiranmay; Reddy, Govardhan

2018-04-01

Small single-domain globular proteins, which are believed to be dominantly two-state folders, played an important role in elucidating various aspects of the protein folding mechanism. However, recent single molecule fluorescence resonance energy transfer experiments [H. Y. Aviram et al. J. Chem. Phys. 148, 123303 (2018)] on a single-domain two-state folding protein L showed evidence for the population of an intermediate state and it was suggested that in this state, a β-hairpin present near the C-terminal of the native protein state is unfolded. We performed molecular dynamics simulations using a coarse-grained self-organized-polymer model with side chains to study the folding pathways of protein L. In agreement with the experiments, an intermediate is populated in the simulation folding pathways where the C-terminal β-hairpin detaches from the rest of the protein structure. The lifetime of this intermediate structure increased with the decrease in temperature. In low temperature conditions, we also observed a second intermediate state, which is globular with a significant fraction of the native-like tertiary contacts satisfying the features of a dry molten globule.

Health domains and race in generic preference-based health-related quality of life instruments in the United States literature

Directory of Open Access Journals (Sweden)

Claudia Cristina de Aguiar Pereira

2010-12-01

Full Text Available Race differences in health have been extensively analyzed and documented in the literature, especially between African Americans or blacks and whites in the United States. Despite the vast literature in the area, the majority of studies that explore the relationship between race and health use outcomes such as self-rated health, mortality or morbidity, and disability, but very few use Health-Related Quality of Life (HRQoL measures and their domains or dimensions. This narrative review aims to provide a better understanding of the relationship between race and health domains that are commonly used in preference-based HRQoL measures. We investigated the literature on race, physical health, mental health, pain and discomfort, cognition, neurologic spectrum domains, dexterity, ambulation, vitality and social functioning domains. We conducted a literature search and review using the key words race and the health domain of interest, using medical and social sciences databases, such as MEDLINE/Pubmed, Web of Science, and the Google Scholar portal.The majority of the studies identified in the literature show that African Americans or blacks in the United States tend to have lower scores than whites throughout a variety of health domains found in preference-based HRQoL measures. This review also emphasizes the scarcity of studies that investigate some health domains, such as social functioning, dexterity, vitality and neurologic spectrum domains, and therefore we identify the need for more studies focusing on race and measures that address such domains.

Dynamics of SARS-coronavirus HR2 domain in the prefusion and transition states

Science.gov (United States)

McReynolds, Susanna; Jiang, Shaokai; Rong, Lijun; Caffrey, Michael

2009-12-01

The envelope glycoproteins S1 and S2 of severe acute respiratory syndrome coronavirus (SARS-CoV) mediate viral entry by conformational change from a prefusion state to a postfusion state that enables fusion of the viral and target membranes. In this work we present the characterization of the dynamic properties of the SARS-CoV S2-HR2 domain (residues 1141-1193 of S) in the prefusion and newly discovered transition states by NMR 15N relaxation studies. The dynamic properties of the different states, which are stabilized under different experimental conditions, extend the current model of viral membrane fusion and give insight into the design of structure-based antagonists of SARS-CoV in particular, as well as other enveloped viruses such as HIV.

The Notice on the Notion of State Aid and Public Procurement Law

DEFF Research Database (Denmark)

Ølykke, Grith Skovgaard

2016-01-01

uncertainty. Then the elaborations made in the Notice on the notion of aid concerning the relation between the two areas of law are analysed and discussed, in particular, first, the question whether adhering to the procurement procedures laid down in the public procurement directives will eliminate the risk......The Commission Notice on the notion of State aid includes elaboration on the relationship between State aid law and public procurement law. To begin with, the article examines some of the reasons why the relationship between State aid law and public procurement law is surrounded by legal...... of granting State aid and, second, the issues rising from State aid control of in-house situations. It is concluded that even though the Notice on the notion of aid brings some needed clarity that fosters coherence between State aid law and public procurement law, the existing legal uncertainty is not even...

Renewable energy policy design and framing influence public support in the United States

Science.gov (United States)

Stokes, Leah C.; Warshaw, Christopher

2017-08-01

The United States has often led the world in supporting renewable energy technologies at both the state and federal level. However, since 2011 several states have weakened their renewable energy policies. Public opinion will probably be crucial for determining whether states expand or contract their renewable energy policies in the future. Here we show that a majority of the public in most states supports renewable portfolio standards, which require a portion of the electricity mix to come from renewables. However, policy design and framing can strongly influence public support. Using a survey experiment, we show that effects of renewable portfolio standards bills on residential electricity costs, jobs and pollution, as well as bipartisan elite support, are all important drivers of public support. In many states, these bills' design and framing can push public opinion above or below majority support.

75 FR 3952 - Delegation by the Under Secretary of State for Public Diplomacy and Public Affairs to the...

Science.gov (United States)

2010-01-25

... Public Diplomacy and Public Affairs to the Coordinator, Bureau of International Information Programs, or... Diplomacy and Public Affairs by law, including by Delegation of Authority No. 234 of October 1, 1999, and... State for Public Diplomacy and Public Affairs may at any time exercise the functions and authorities...

A hybrid fault diagnosis approach based on mixed-domain state features for rotating machinery.

Science.gov (United States)

Xue, Xiaoming; Zhou, Jianzhong

2017-01-01

To make further improvement in the diagnosis accuracy and efficiency, a mixed-domain state features data based hybrid fault diagnosis approach, which systematically blends both the statistical analysis approach and the artificial intelligence technology, is proposed in this work for rolling element bearings. For simplifying the fault diagnosis problems, the execution of the proposed method is divided into three steps, i.e., fault preliminary detection, fault type recognition and fault degree identification. In the first step, a preliminary judgment about the health status of the equipment can be evaluated by the statistical analysis method based on the permutation entropy theory. If fault exists, the following two processes based on the artificial intelligence approach are performed to further recognize the fault type and then identify the fault degree. For the two subsequent steps, mixed-domain state features containing time-domain, frequency-domain and multi-scale features are extracted to represent the fault peculiarity under different working conditions. As a powerful time-frequency analysis method, the fast EEMD method was employed to obtain multi-scale features. Furthermore, due to the information redundancy and the submergence of original feature space, a novel manifold learning method (modified LGPCA) is introduced to realize the low-dimensional representations for high-dimensional feature space. Finally, two cases with 12 working conditions respectively have been employed to evaluate the performance of the proposed method, where vibration signals were measured from an experimental bench of rolling element bearing. The analysis results showed the effectiveness and the superiority of the proposed method of which the diagnosis thought is more suitable for practical application. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Public health surveillance of cancer survival in the United States and worldwide: The contribution of the CONCORD programme.

Science.gov (United States)

Allemani, Claudia; Coleman, Michel P

2017-12-15

CONCORD is a programme for the global surveillance of cancer survival. In 2015, the second cycle of the program (CONCORD-2) established long-term surveillance of cancer survival worldwide, for the first time, in the largest cancer survival study published to date. CONCORD-2 provided cancer survival trends for 25,676,887 patients diagnosed during the 15-year period between 1995 and 2009 with 1 of 10 common cancers that collectively represented 63% of the global cancer burden in 2009. Herein, the authors summarize the past, describe the present, and outline the future of the CONCORD programme. They discuss the difference between population-based studies and clinical trials, and review the importance of international comparisons of population-based cancer survival. This study will focus on the United States. The authors explain why population-based survival estimates are crucial for driving effective cancer control strategies to reduce the wide and persistent disparities in cancer survival between white and black patients, which are likely to be attributable to differences in access to early diagnosis and optimal treatment. Cancer 2017;123:4977-81. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

[Public control and equity of access to hospitals under non-State public administration].

Science.gov (United States)

Carneiro Junior, Nivaldo; Elias, Paulo Eduardo

2006-10-01

To analyze social health organizations in the light of public control and the guarantee of equity of access to health services. Utilizing the case study technique, two social health organizations in the metropolitan region of São Paulo were selected. The analytical categories were equity of access and public control, and these were based on interviews with key informants and technical-administrative reports. It was observed that the overall funding and administrative control of the social health organizations are functions of the state administrator. The presence of a local administrator is important for ensuring equity of access. Public control is expressed through supervisory actions, by means of accounting and financial procedures. Equity of access and public control are not taken into consideration in the administration of these organizations. The central question lies in the capacity of the public authorities to have a presence in implementing this model at the local level, thereby ensuring equity of access and taking public control into consideration.

State Aid as a Defence for Public Authorities?

DEFF Research Database (Denmark)

Ølykke, Grith Skovgaard

2016-01-01

court’s perception. As the contracts had been declared to be in force by a declaratory judgment that was res judicata, the dispute before the CJEU concerned the national interpretation of the principle of res judicata and its application in a State aid context. The CJEU first turned to the principle......In the annotated judgment a public authority uses the existence of State aid as a defence in a legal action, where its contractual partner aimed to achieve damages and fulfilment of the contracts. The public authority claimed that the contracts were not on market terms, which also was the national...... of consistent interpretation, which it considered could provide various solutions for the national court to draw all the necessary consequences of the possible breach of the duty to notify State aid. In the alternative, the CJEU considered the principle of effectiveness and found that due to the fundamental...

Award of Public Contracts as a Means to Conferring State Aid

DEFF Research Database (Denmark)

Fanøe Petersen, Cecilie

The Thesis investigates the interface between State aid law and public procurement law with an emphasis on analysing when the award of public contracts by contracting authorities constitutes State aid within the meaning of Article 107(1) TFEU. Article 107(1) TFEU prohibits any aid granted by a Me...

State Public Health Enabling Authorities: Results of a Fundamental Activities Assessment Examining Core and Essential Services

Science.gov (United States)

Hoss, Aila; Menon, Akshara; Corso, Liza

2016-01-01

Context Public health enabling authorities establish the legal foundation for financing, organizing, and delivering public health services. State laws vary in terms of the content, depth, and breadth of these fundamental public health activities. Given this variance, the Institute of Medicine has identified state public health laws as an area that requires further examination. To respond to this call for further examination, the Centers for Disease Control and Prevention’s Public Health Law Program conducted a fundamental activities legal assessment on state public health laws. Objective The goal of the legal assessment was to examine state laws referencing frameworks representing public health department fundamental activities (ie, core and essential services) in an effort to identify, catalog, and describe enabling authorities of state governmental public health systems. Design In 2013, Public Health Law Program staff compiled a list of state statutes and regulations referencing different commonly-recognized public health frameworks of fundamental activities. The legal assessment included state fundamental activities laws available on WestlawNext as of July 2013. The results related to the 10 essential public health services and the 3 core public health functions were confirmed and updated in June 2016. Results Eighteen states reference commonly-recognized frameworks of fundamental activities in their laws. Thirteen states have listed the 10 essential public health services in their laws. Eight of these states have also referenced the 3 core public health functions in their laws. Five states reference only the core public health functions. Conclusions Several states reference fundamental activities in their state laws, particularly through use of the essential services framework. Further work is needed to capture the public health laws and practices of states that may be performing fundamental activities but without reference to a common framework. PMID

State Public Health Enabling Authorities: Results of a Fundamental Activities Assessment Examining Core and Essential Services.

Science.gov (United States)

Hoss, Aila; Menon, Akshara; Corso, Liza

2016-01-01

Public health enabling authorities establish the legal foundation for financing, organizing, and delivering public health services. State laws vary in terms of the content, depth, and breadth of these fundamental public health activities. Given this variance, the Institute of Medicine has identified state public health laws as an area that requires further examination. To respond to this call for further examination, the Centers for Disease Control and Prevention's Public Health Law Program conducted a fundamental activities legal assessment on state public health laws. The goal of the legal assessment was to examine state laws referencing frameworks representing public health department fundamental activities (ie, core and essential services) in an effort to identify, catalog, and describe enabling authorities of state governmental public health systems. In 2013, Public Health Law Program staff compiled a list of state statutes and regulations referencing different commonly-recognized public health frameworks of fundamental activities. The legal assessment included state fundamental activities laws available on WestlawNext as of July 2013. The results related to the 10 essential public health services and the 3 core public health functions were confirmed and updated in June 2016. Eighteen states reference commonly-recognized frameworks of fundamental activities in their laws. Thirteen states have listed the 10 essential public health services in their laws. Eight of these states have also referenced the 3 core public health functions in their laws. Five states reference only the core public health functions. Several states reference fundamental activities in their state laws, particularly through use of the essential services framework. Further work is needed to capture the public health laws and practices of states that may be performing fundamental activities but without reference to a common framework.

Effects of the Strategic Prevention Framework State Incentives Grant (SPF SIG) on state prevention infrastructure in 26 states.

Science.gov (United States)

Orwin, Robert G; Stein-Seroussi, Alan; Edwards, Jessica M; Landy, Ann L; Flewelling, Robert L

2014-06-01

The Strategic Prevention Framework State Incentive Grant (SPF SIG) program is a national public health initiative sponsored by the U.S. Substance Abuse and Mental Health Services Administration's Center for Substance Abuse Prevention to prevent substance abuse and its consequences. State grantees used a data-driven planning model to allocate resources to 450 communities, which in turn launched over 2,200 intervention strategies to target prevention priorities in their respective populations. An additional goal was to build prevention capacity and infrastructure at the state and community levels. This paper addresses whether the state infrastructure goal was achieved, and what contextual and implementation factors were associated with success. The findings are consistent with claims that, overall, the SPF SIG program met its goal of increasing prevention capacity and infrastructure across multiple infrastructure domains, though the mediating effects of implementation were evident only in the evaluation/monitoring domain. The results also show that an initiative like the SPF SIG, which could easily have been compartmentalized within the states, has the potential to permeate more broadly throughout state prevention systems.

75 FR 6643 - Publication of State Plan Pursuant to the Help America Vote Act

Science.gov (United States)

2010-02-10

... ELECTION ASSISTANCE COMMISSION Publication of State Plan Pursuant to the Help America Vote Act... plans previously submitted by New Jersey and Wisconsin. DATES: This notice is effective upon publication... the State plans submitted for publication provide information on how the respective State succeeded in...

Using the laws and the regularities of public administration in the state strategic planning

Directory of Open Access Journals (Sweden)

O. L. Yevmieshkina

2016-03-01

Full Text Available The article researches the use of laws of public administration in the state strategic planning; defined a methodological basis of state strategic planning. State strategic planning as a function of public administration exists in accordance with its laws and regularities. Author established the use of public administration laws as: unity socio-economic system, required diversity, system integrity, unity techniques and basic functions of social management at all levels of public administration: central, sectorial, regional. At the public administration level this laws as a rule us in working and realization of state strategy, state, region and sectorial program, which directed to improve of political, economic and social process. State strategic planning as a function of public administration exists in accordance with its laws. The law in our research is considered as objective, substantive, necessary, sustainable relationship between events. The most essential feature of law is reflecting the objective state of affairs, objective relations between things, items and phenomenon’s. The other difficult sign of law is necessity as relation, which inevitably revealed in the development process of different things. Law category with regularity category is relation. Regularity is wider category then the law. The state strategic planning is an integrated, systematic process due to the action and use laws and regularities of public administration. That improves the efficiency of public administration.

The Public Diplomacy Resources Of The Union State Of Russia And Belarus

Directory of Open Access Journals (Sweden)

K. P. Borishpolets

2017-01-01

Full Text Available Public diplomacy has become a common attribute of the global political life since the early 21 century. The interest for the public diplomacy is also evident among the EEU countries. Nevertheless, the question of the public diplomacy resource savailable for the integrating post-Soviet states and their usage remains open. The practice of the Union State of Russia and Belarus (USRB is characterized by a wide range of public initiatives to increase the public attractiveness of the bilateral integration project. It communicates with a broad international environment and thereby creates a positive image for the Russian-Belarusian partnership. Public diplomacy of the USRB is a complex phenomenon combining various functional components, mechanisms and. Two mutually complementary vectors in its development can be distinguished, the first one related to the actions of officials and leaders of partner countries, and the second one – to the practice of non-state actors in the form of public organizations, business communities, academics, and the media. The state institutions along with the special social structures are actively involved in different projects boosting the international public image of USRB and play a critical part in creating a positive image of the Russian-Belarus cooperation. This fact represents the growing structural interaction of the traditional and new actors of the world political processes.

78 FR 77110 - Publication of State Plan Pursuant to the Help America Vote Act

Science.gov (United States)

2013-12-20

... ELECTION ASSISTANCE COMMISSION Publication of State Plan Pursuant to the Help America Vote Act... at www.eac.gov . DATES: This notice is effective upon publication in the Federal Register. FOR... publication provide information on how the respective State succeeded in carrying out its previous State plan...

Where Money Mattered: Organizational and Economic Consequences of State Public School Expenditures in the United States: 1880-1940.

Science.gov (United States)

Balfanz, Robert

1997-01-01

Uses historical, state-level schooling data, manufacturing productivity measures, and quantitative research to examine relationships between changes in rate and distribution of public school expenditures, public schooling organization, and state-level economic growth from 1880-1940. Significant effects for per-student spending on school…

A new frequency-domain criterion for elimination of limit cycles in fixed-point state-space digital filters using saturation arithmetic

International Nuclear Information System (INIS)

Singh, Vimal

2007-01-01

In [Singh V. Elimination of overflow oscillations in fixed-point state-space digital filters using saturation arithmetic. IEEE Trans Circ Syst 1990;37(6):814-8], a frequency-domain criterion for the suppression of limit cycles in fixed-point state-space digital filters using saturation overflow arithmetic was presented. The passivity property owing to the presence of multiple saturation nonlinearities was exploited therein. In the present paper, a new notion of passivity, namely, that involving the state variables is considered, thereby arriving at an entirely new frequency-domain criterion for the suppression of limit cycles in such filters

PUBLIC ADMINISTRATION: MODERNIZING THE CURRENT MODEL OF STATE MANAGEMENT

Directory of Open Access Journals (Sweden)

Evgenii V. Ohotskii

2014-01-01

Full Text Available Applying the method of retrospective analysis the article deals with the process of forming the scientific fundamentals and the search by the international community of effective and adequate to the current stage of social development public administration system. The author attempts to analyze, in a number of cases in terms of models, features of public administration systems at different stages of historical development, drawing attention to reasons why the Soviet model of public administration did not manage to meet competition, did not provide the required social effect and as a natural result suffered a defeat in the global confrontation between the two social systems. Current models and theoretical concepts of public administration, especially the "new public administration", which became scientific basis for administrative reforms implemented in many countries, are the particular subject of scientific analysis. The author draws attention to major comprehensive characteristics of modern state public administration: making it impossible to absolutize principles of traditional hierarchy system of forced administration; globalization - gradual destruction of boundaries between national and international levels of administration, the growing role of supranational subjects of administration relations; informatization - increasing importance of information and communication technologies and of political networks: development of civil society, especially political parties and non-governmental organizations, growing public involvement in discussion and adoption of the most important administrative decisions; making the state policy more pluralistic and which will result in the formation of nonlinear - humanistic social consciousness as the intellectual basis of modern social governance. The author's position is that Russia is yet to solve the issue of choosing a public administration model that would be effective for further administrative

DAE emergency response centre (ERC) at Kalpakkam for response to nuclear and radiological emergencies in public domain

International Nuclear Information System (INIS)

Meenakshisundaram, V.; Rajagopal, V.; Mathiyarasu, R.; Subramanian, V.; Rajaram, S.; Somayaji, K.M.; Kannan, V.; Rajagopalan, H.

2008-01-01

In India, Department of Atomic Energy (DAE) has been identified as the nodal agency/authority in respect of providing the necessary technical inputs in the event of any radiation emergency that may occur in public domain. The overall system takes into consideration statutory requirements, executive decisions as well as National and International obligations. This paper highlights the details about the strength of the Kalpakkam ERC and other essential requisites and their compliance since its formation

Policy Perspectives on State Elementary and Secondary Public Education Finance Systems in the United States

Science.gov (United States)

Verstegen, Deborah A.

2016-01-01

The purpose of this article is to describe and compare individual state funding systems for public elementary and secondary education in the United States. States' major education funding systems are described as well as funding mechanisms for students with disabilities; English language learners (ELL); gifted and talented students; and low income…

State Policy Snapshot: School District Facilities and Public Charter Schools

Science.gov (United States)

Simnick, Russ

2015-01-01

One of the greatest challenges to the health of the public charter school movement is access to adequate facilities in which the schools operate. Public charter school facilities are rarely funded on par with school district facilities. Over the years, more states have come to realize that they have an obligation to ensure that all public school…

78 FR 17716 - Notice Seeking Public Interest for Solar Energy Development on Public Lands in the State of Colorado

Science.gov (United States)

2013-03-22

... Public Interest for Solar Energy Development on Public Lands in the State of Colorado AGENCY: Bureau of... State Office is providing an opportunity for parties to express an interest in proposing solar energy... two designated Solar Energy Zones (SEZs) serialized as COC-074761 (Los Mogotes East SEZ) and COC...

Power distribution, the environment, and public health. A state-level analysis

International Nuclear Information System (INIS)

Boyce, James K.; Klemer, Andrew R.; Templet, Paul H.; Willis, Cleve E.

1999-01-01

This paper examines relationships among power distribution, the environment, and public health by means of a cross-sectional analysis of the 50 US states. A measure of inter-state variations in power distribution is derived from data on voter participation, tax fairness, Medicaid access, and educational attainment. We develop and estimate a recursive model linking the distribution of power to environmental policy, environmental stress, and public health. The results support the hypothesis that greater power inequality leads to weaker environmental policies, which in turn lead to greater environmental degradation and to adverse public health outcomes

Power distribution, the environment, and public health. A state-level analysis

Energy Technology Data Exchange (ETDEWEB)

Boyce, James K. [Department of Economics, University of Massachusetts, Amherst, MA 01003 (United States); Klemer, Andrew R. [Department of Biology, University of Minnesota, Duluth, MN (United States); Templet, Paul H. [Institute of Environmental Studies, Louisiana State University, Baton Rouge, LA (United States); Willis, Cleve E. [Department of Resource Economics, University of Massachusetts, Amherst, MA 01003 (United States)

1999-04-15

This paper examines relationships among power distribution, the environment, and public health by means of a cross-sectional analysis of the 50 US states. A measure of inter-state variations in power distribution is derived from data on voter participation, tax fairness, Medicaid access, and educational attainment. We develop and estimate a recursive model linking the distribution of power to environmental policy, environmental stress, and public health. The results support the hypothesis that greater power inequality leads to weaker environmental policies, which in turn lead to greater environmental degradation and to adverse public health outcomes.

Power distribution, the environment, and public health. A state-level analysis

Energy Technology Data Exchange (ETDEWEB)

Boyce, James K. [Department of Economics, University of Massachusetts, Amherst, MA 01003 (United States); Klemer, Andrew R. [Department of Biology, University of Minnesota, Duluth, MN (United States); Templet, Paul H. [Institute of Environmental Studies, Louisiana State University, Baton Rouge, LA (United States); Willis, Cleve E. [Department of Resource Economics, University of Massachusetts, Amherst, MA 01003 (United States)

1999-04-15

This paper examines relationships among power distribution, the environment, and public health by means of a cross-sectional analysis of the 50 US states. A measure of inter-state variations in power distribution is derived from data on voter participation, tax fairness, Medicaid access, and educational attainment. We develop and estimate a recursive model linking the distribution of power to environmental policy, environmental stress, and public health. The results support the hypothesis that greater power inequality leads to weaker environmental policies, which in turn lead to greater environmental degradation and to adverse public health outcomes

Public consultation in public policy information: a state-of-the-art report

International Nuclear Information System (INIS)

Bishop, A.B.; McKee, M.; Hansen, R.D.

1977-01-01

The purpose of the National Waste Terminal Storage (NWTS) Program is to site, construct and operate nuclear waste repositories at several locations. Recent experience indicates that the public is aware of the problems of nuclear waste disposal, and correspondingly there is public concern about how and where to dispose of nuclear wastes. The selection of sites involves a wide range of considerations including geological, technical and environmental feasibility. In addition to these, it is important that societal acceptance of repository options also be taken into account in moving foward with the NWTS Program. Such an incorporation of social considerations and preferences correspondingly implies the need for public consultation in the site selection process. In exploring the concept and state-or-the-art of public involvement in public policy decision, a number of important questions are relevant: (1) What are the basic objectives of public participation in policy formation and program decisions. (2) Who are the ''publics'' that should be involved and how can they be identified. (3) What information should be communicated between the agency and the publics. (4) What techniques are available to elicit public participation and involvement and what are their capabilities. At the outset, it should be noted that the purpose of this paper in addressing these questions is not to design public participation procedures for the NWTS program. Rather, the above are questions that provide a broad framework for developing an understanding of citizen participation in public policy decisions, such as nuclear waste disposal. In this sense, the following discussion is to provide a context and guidance for approaching the problem of organizing and structuring involvement in the NWTS program. Annotated bibliography of 95 references is included

Public consultation in public policy information: a state-of-the-art report

Energy Technology Data Exchange (ETDEWEB)

Bishop, A.B.; McKee, M.; Hansen, R.D.

1977-01-01

The purpose of the National Waste Terminal Storage (NWTS) Program is to site, construct and operate nuclear waste repositories at several locations. Recent experience indicates that the public is aware of the problems of nuclear waste disposal, and correspondingly there is public concern about how and where to dispose of nuclear wastes. The selection of sites involves a wide range of considerations including geological, technical and environmental feasibility. In addition to these, it is important that societal acceptance of repository options also be taken into account in moving foward with the NWTS Program. Such an incorporation of social considerations and preferences correspondingly implies the need for public consultation in the site selection process. In exploring the concept and state-or-the-art of public involvement in public policy decision, a number of important questions are relevant: (1) What are the basic objectives of public participation in policy formation and program decisions. (2) Who are the ''publics'' that should be involved and how can they be identified. (3) What information should be communicated between the agency and the publics. (4) What techniques are available to elicit public participation and involvement and what are their capabilities. At the outset, it should be noted that the purpose of this paper in addressing these questions is not to design public participation procedures for the NWTS program. Rather, the above are questions that provide a broad framework for developing an understanding of citizen participation in public policy decisions, such as nuclear waste disposal. In this sense, the following discussion is to provide a context and guidance for approaching the problem of organizing and structuring involvement in the NWTS program. Annotated bibliography of 95 references is included.

An Examination of State Funding Models Regarding Virtual Schools for Public Elementary and Secondary Education in the United States

Science.gov (United States)

Stedrak, Luke J.

2012-01-01

This study contains an analysis of virtual schools, public policy, and funding in the United States. The purpose of this study was to determine what public policies and legislation were in place regarding the funding models of virtual education on a state by state basis. Furthermore, this study addressed how allocations were being made by state…

State Outlook: Fiscal and Public Policy Issues Affecting Postsecondary Education

Science.gov (United States)

American Association of State Colleges and Universities, 2010

2010-01-01

This publication provides a compilation of the issues affecting postsecondary education in America. The contents of this issue include: (1) Overview of Economic and Fiscal Policy Dynamics; (2) July 2010 Economic Snapshot; (3) State Economic Conditions and Budget Outlook; (4) State Budget Pressures; (5) State Budget Realignment Strategies; (6)…

2000-2010 Annual State-Scale Service and Domain Scores for Forecasting Well-Being from Service-Based Decisions

Data.gov (United States)

U.S. Environmental Protection Agency — 2000-2010 Annual State-Scale Service and Domain scores used to support the approach for forecasting EPA's Human Well-Being Index. A modeling approach was developed...

Governmental public health in the United States: the implications of federalism.

Science.gov (United States)

Turnock, Bernard J; Atchison, Christopher

2002-01-01

Governmental public health activities in the United States have evolved over time as a result of two forces: the nature and perceived importance of threats to the population's health and safety, and changing relationships among the various levels of government. Shifts toward a more state-centered form of federalism in the second half of the twentieth century weakened key aspects of the governmental public health enterprise, including its leadership and coordination, by the century's end. These developments challenge governmental public health responses to the new threats and increased societal expectations of the early twenty-first century.

FINANCIAL AUDIT AS A PART OF STATE ADMINISTRATION IN UKRAINE: CONDITION AND PUBLIC NEED

Directory of Open Access Journals (Sweden)

Sergey Bardash

2016-11-01

Full Text Available Economic development of countries leads to the need improving the quality of public administration, the results of which provide economic growth, social prosperity and are facilitating to solve global problems that are facing humanity. To improve the efficiency of public administration should be effective monitoring system that can detect deviations from the planned strategic development goals, unseemly level of its operation determines the target of work, which is to establish the condition of the state financial audit in Ukraine and the definition of new uncontrollable earlier objects which are managed the state apparatus, the identification of which will improve the functionality of the system of state financial audit in Ukraine. In order to achieve the goals you need to solve the following tasks. First, should set a condition of the state economic management in Ukraine and determine the public authorities, which are subjects to implementing control functions of public administration. Second, determine the resources that have the public interest and should be controlled by the state. Third, determine the composition of objects and install a condition of government auditing system in order to improve the efficiency of these next control measures of the Accounting Chamber of Ukraine and the State Audit Service of Ukraine. The methodological basis of the study is the dialectical method, which is to implement research of financial audit in public administration, its relationship with other forms of control exercised by the state; systematic analysis of financial and economic processes, which is carrying out researching of the state financial audit in the system of relations arising between economic entities of the public and private sectors; methods of retrospective and comparative analysis of experience within the objective focus in the organization of state financial audit on the territory of Ukraine; evaluation and generalization which

Sources and Resources Into the Dark Domain: The UK Web Archive as a Source for the Contemporary History of Public Health.

Science.gov (United States)

Gorsky, Martin

2015-08-01

With the migration of the written record from paper to digital format, archivists and historians must urgently consider how web content should be conserved, retrieved and analysed. The British Library has recently acquired a large number of UK domain websites, captured 1996-2010, which is colloquially termed the Dark Domain Archive while technical issues surrounding user access are resolved. This article reports the results of an invited pilot project that explores methodological issues surrounding use of this archive. It asks how the relationship between UK public health and local government was represented on the web, drawing on the 'declinist' historiography to frame its questions. It points up some difficulties in developing an aggregate picture of web content due to duplication of sites. It also highlights their potential for thematic and discourse analysis, using both text and image, illustrated through an argument about the contradictory rationale for public health policy under New Labour.

Civil rights as determinants of public health and racial and ethnic health equity: Health care, education, employment, and housing in the United States.

Science.gov (United States)

Hahn, R A; Truman, B I; Williams, D R

2018-04-01

This essay examines how civil rights and their implementation have affected and continue to affect the health of racial and ethnic minority populations in the United States. Civil rights are characterized as social determinants of health. A brief review of US history indicates that, particularly for Blacks, Hispanics, and American Indians, the longstanding lack of civil rights is linked with persistent health inequities. Civil rights history since 1950 is explored in four domains-health care, education, employment, and housing. The first three domains show substantial benefits when civil rights are enforced. Discrimination and segregation in housing persist because anti-discrimination civil rights laws have not been well enforced. Enforcement is an essential component for the success of civil rights law. Civil rights and their enforcement may be considered a powerful arena for public health theorizing, research, policy, and action.

75 FR 51759 - Publication of State Plan Pursuant to the Help America Vote Act

Science.gov (United States)

2010-08-23

... ELECTION ASSISTANCE COMMISSION Publication of State Plan Pursuant to the Help America Vote Act... previously submitted by California. DATES: This notice is effective upon publication in the Federal Register... plans submitted for publication provide information on how the respective state succeeded in carrying...

Linking public relations processes and organizational effectiveness at a state health department.

Science.gov (United States)

Wise, Kurt

2003-01-01

This qualitative case study explored a state health department's relationships with strategic constituencies from a public relations perspective. The relationships were explored within the theoretical framework of the Excellence Theory, the dominant paradigm in public research. Findings indicate application of the Excellence Theory has the potential to increase organizational effectiveness at public health entities. With respect to the case investigated, findings indicate that the state health department could increase its organizational effectiveness through the adoption of recommendations based on the Excellence Theory.

75 FR 39671 - Publication of State Plan Pursuant to the Help America Vote Act

Science.gov (United States)

2010-07-12

... ELECTION ASSISTANCE COMMISSION Publication of State Plan Pursuant to the Help America Vote Act... plan previously submitted by South Dakota. DATES: This notice is effective upon publication in the... 254(a)(12), all the state plans submitted for publication provide information on how the respective...

75 FR 41454 - Publication of State Plan Pursuant to the Help America Vote Act

Science.gov (United States)

2010-07-16

... ELECTION ASSISTANCE COMMISSION Publication of State Plan Pursuant to the Help America Vote Act... plans previously submitted by Alaska. DATES: This notice is effective upon publication in the Federal... programs. In accordance with HAVA Section 254(a)(12), all the state plans submitted for publication provide...

Solar Photovoltaic Financing: Deployment on Public Property by State and Local Governments

Energy Technology Data Exchange (ETDEWEB)

Cory, K.; Coughlin, J.; Coggeshall, C.

2008-05-01

State and local governments have grown increasingly aware of the economic, environmental, and societal benefits of taking a lead role in U.S. implementation of renewable energy, particularly distributed photovoltaic (PV) installations. Recently, solar energy's cost premium has declined as a result of technology improvements and an increase in the cost of traditional energy generation. At the same time, a nationwide public policy focus on carbon-free, renewable energy has created a wide range of financial incentives to lower the costs of deploying PV even further. These changes have led to exponential increases in the availability of capital for solar projects, and tremendous creativity in the development of third-party ownership structures. As significant users of electricity, state and local governments can be an excellent example for solar PV system deployment on a national scale. Many public entities are not only considering deployment on public building rooftops, but also large-scale applications on available public lands. The changing marketplace requires that state and local governments be financially sophisticated to capture as much of the economic potential of a PV system as possible. This report examines ways that state and local governments can optimize the financial structure of deploying solar PV for public uses.

Feature-level domain adaptation

DEFF Research Database (Denmark)

Kouw, Wouter M.; Van Der Maaten, Laurens J P; Krijthe, Jesse H.

2016-01-01

-level domain adaptation (flda), that models the dependence between the two domains by means of a feature-level transfer model that is trained to describe the transfer from source to target domain. Subsequently, we train a domain-adapted classifier by minimizing the expected loss under the resulting transfer...... modeled via a dropout distribution, which allows the classiffier to adapt to differences in the marginal probability of features in the source and the target domain. Our experiments on several real-world problems show that flda performs on par with state-of-the-art domainadaptation techniques.......Domain adaptation is the supervised learning setting in which the training and test data are sampled from different distributions: training data is sampled from a source domain, whilst test data is sampled from a target domain. This paper proposes and studies an approach, called feature...

State landscape in public health planning and quality improvement: results of the ASTHO survey.

Science.gov (United States)

Madamala, Kusuma; Sellers, Katie; Pearsol, Jim; Dickey, Michael; Jarris, Paul E

2010-01-01

Limited data exist on state public health agencies and their use of planning and quality improvement (QI) initiatives. Using the 2007 Association of State and Territorial Health Officials (ASTHO) State Public Health Survey, this article describes how state public health agencies perform tasks related to planning, performance management (PM), and QI. While 82 percent of respondents report having a QI process in place, only 9.8 percent have it fully implemented departmentwide. Seventy-six percent reported having a PM process in place, with 16 percent (n = 8) having it fully implemented departmentwide. A state health improvement plan was used by 80.4 percent of respondents, with 56.9 percent of respondents completing the plan more than 3 years ago. More than two-thirds (68.2%) of the respondents developed the plan by using results of their state health assessment. Analysis of state health department level planning, PM, and QI initiatives can inform states' efforts to ready themselves to meet the proposed national voluntary accreditation standards of the Public Health Accreditation Board.

77 FR 75425 - Publication of State Plan Pursuant to the Help America Vote Act

Science.gov (United States)

2012-12-20

... ELECTION ASSISTANCE COMMISSION Publication of State Plan Pursuant to the Help America Vote Act... site at www.eac.gov . DATES: This notice is effective upon publication in the Federal Register. FOR... with HAVA Section 254(a)(12), all the State plans submitted for publication provide information on how...

Public supply and domestic water use in the United States, 2015

Science.gov (United States)

Dieter, Cheryl A.; Maupin, Molly A.

2017-10-30

IntroductionThe U.S. Geological Survey (USGS) National Water Use Science Project (NWUSP), part of the USGS Water Availability and Use Science Program (WAUSP), has estimated water use in the United States every 5 years since 1950. This report provides an overview of total population, public-supply use, including the population that is served by public-supply systems and the domestic deliveries to those users, and self-supplied domestic water use in the United States for 2015, continuing the task of estimating water use in the United States every 5 years. In this report, estimates for the United States include the 50 States, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands (hereafter referred to as “states” for brevity).County-level data for total population, public-supply withdrawals and the population served by public-supply systems, and domestic withdrawals for 2015 were published in a data release in an effort to provide data to the public in a timely manner. Data in the current version (1.0) of Dieter and others (2017) contains county-level total withdrawals from groundwater and surface-water sources (both fresh and saline) for public-water supply, the deliveries from those suppliers to domestic users, and the quantities of water from groundwater and surface-water sources for self-supplied domestic users, and total population. Methods used to estimate the various data elements for the public-supply and domestic use categories at the county level are described by Bradley (2017).This Open-File Report is an interim report summarizing the data published in Dieter and others (2017) at the state and national level. This report includes discussions on the total population, totals for public-supply withdrawals and population served, total domestic withdrawals, and provides comparisons of the 2015 estimates to 2010 estimates (Maupin and others, 2014). Total domestic water use, as described in this report, represents the summation of deliveries from

A Logic for Inclusion of Administrative Domains and Administrators in Multi-domain Authorization

Science.gov (United States)

Iranmanesh, Zeinab; Amini, Morteza; Jalili, Rasool

Authorization policies for an administrative domain or a composition of multiple domains in multi-domain environments are determined by either one administrator or multiple administrators' cooperation. Several logic-based models for multi-domain environments' authorization have been proposed; however, they have not considered administrators and administrative domains in policies' representation. In this paper, we propose the syntax, proof theory, and semantics of a logic for multi-domain authorization policies including administrators and administrative domains. Considering administrators in policies provides the possibility of presenting composite administration having applicability in many collaborative applications. Indeed, administrators and administrative domains stated in policies can be used in authorization. The presented logic is based on modal logic and utilizes two calculi named the calculus of administrative domains and the calculus of administrators. It is also proved that the logic is sound. A case study is presented signifying the logic application in practical projects.

Dynamics of domain coverage of the protein sequence universe

Science.gov (United States)

2012-01-01

Background The currently known protein sequence space consists of millions of sequences in public databases and is rapidly expanding. Assigning sequences to families leads to a better understanding of protein function and the nature of the protein universe. However, a large portion of the current protein space remains unassigned and is referred to as its “dark matter”. Results Here we suggest that true size of “dark matter” is much larger than stated by current definitions. We propose an approach to reducing the size of “dark matter” by identifying and subtracting regions in protein sequences that are not likely to contain any domain. Conclusions Recent improvements in computational domain modeling result in a decrease, albeit slowly, in the relative size of “dark matter”; however, its absolute size increases substantially with the growth of sequence data. PMID:23157439

Dynamics of domain coverage of the protein sequence universe

Directory of Open Access Journals (Sweden)

Rekapalli Bhanu

2012-11-01

Full Text Available Abstract Background The currently known protein sequence space consists of millions of sequences in public databases and is rapidly expanding. Assigning sequences to families leads to a better understanding of protein function and the nature of the protein universe. However, a large portion of the current protein space remains unassigned and is referred to as its “dark matter”. Results Here we suggest that true size of “dark matter” is much larger than stated by current definitions. We propose an approach to reducing the size of “dark matter” by identifying and subtracting regions in protein sequences that are not likely to contain any domain. Conclusions Recent improvements in computational domain modeling result in a decrease, albeit slowly, in the relative size of “dark matter”; however, its absolute size increases substantially with the growth of sequence data.

Time evolution of one-dimensional gapless models from a domain wall initial state: stochastic Loewner evolution continued?

International Nuclear Information System (INIS)

Calabrese, Pasquale; Hagendorf, Christian; Doussal, Pierre Le

2008-01-01

We study the time evolution of quantum one-dimensional gapless systems evolving from initial states with a domain wall. We generalize the path integral imaginary time approach that together with boundary conformal field theory allows us to derive the time and space dependence of general correlation functions. The latter are explicitly obtained for the Ising universality class, and the typical behavior of one- and two-point functions is derived for the general case. Possible connections with the stochastic Loewner evolution are discussed and explicit results for one-point time dependent averages are obtained for generic κ for boundary conditions corresponding to stochastic Loewner evolution. We use this set of results to predict the time evolution of the entanglement entropy and obtain the universal constant shift due to the presence of a domain wall in the initial state

The Health of the Public Charter School Movement: A State-by-State Analysis. Second Edition

Science.gov (United States)

Ziebarth, Todd; Bierlein Palmer, Louann

2016-01-01

In October 2014, the first edition of "The Health of the Public Charter School Movement: A State-by-State Analysis" was released. Both encouraging words and constructive criticism for how to improve the report going forward were received. This second edition builds on the solid foundation of the inaugural version, while making…

Thermal stability of bubble domains in ferromagnetic discs

Energy Technology Data Exchange (ETDEWEB)

Hrkac, G [University of Sheffield, Engineering Materials, Mappin Street, Sheffield S1 3JD (United Kingdom) ; Bance, S [University of Sheffield, Engineering Materials, Mappin Street, Sheffield S1 3JD (United Kingdom) ; Goncharov, A [University of Sheffield, Engineering Materials, Mappin Street, Sheffield S1 3JD (United Kingdom) ; Schrefl, T [University of Sheffield, Engineering Materials, Mappin Street, Sheffield S1 3JD (United Kingdom) ; Suess, D [Vienna University of Technology, Wiedner Hauptstr. 8-10e, A-1040 Vienna (Austria)

2007-05-07

The transition and thermal stability of disc-shaped ferromagnetic particles at the temperature of T = 300 K with a uniaxial anisotropy along the symmetry axis from a bi-domain to a single domain state has been studied. The nudge elastic band method was used to map the energy landscape and to calculate the energy barrier between the transition states. For single FePt disc-shaped particles with perpendicular anisotropy three transition configurations have been found: single domain, stripe- and stable bubble domains at zero applied field. The single domain configuration along the positive anisotropy axis is reached by an annihilation process of the domain wall and the all-down state by a complex domain expansion process. Magnetization configurations in two interacting discs show an increase in thermal stability compared with single disc systems, which is attributed to the interacting magnetostatic energy between the two particles.

Thermal stability of bubble domains in ferromagnetic discs

International Nuclear Information System (INIS)

Hrkac, G; Bance, S; Goncharov, A; Schrefl, T; Suess, D

2007-01-01

The transition and thermal stability of disc-shaped ferromagnetic particles at the temperature of T = 300 K with a uniaxial anisotropy along the symmetry axis from a bi-domain to a single domain state has been studied. The nudge elastic band method was used to map the energy landscape and to calculate the energy barrier between the transition states. For single FePt disc-shaped particles with perpendicular anisotropy three transition configurations have been found: single domain, stripe- and stable bubble domains at zero applied field. The single domain configuration along the positive anisotropy axis is reached by an annihilation process of the domain wall and the all-down state by a complex domain expansion process. Magnetization configurations in two interacting discs show an increase in thermal stability compared with single disc systems, which is attributed to the interacting magnetostatic energy between the two particles

Multiple Case Studies of Public Library Systems in New York State: Service Decision-Making Processes

Science.gov (United States)

Ren, Xiaoai

2012-01-01

This research examined the functions and roles of public library systems in New York State and the services they provide for individual libraries and the public. The dissertation further studied the service decision-making processes at three selected New York State cooperative public library systems. Public library systems have played an important…

Quality improvement and accreditation readiness in state public health agencies.

Science.gov (United States)

Madamala, Kusuma; Sellers, Katie; Beitsch, Leslie M; Pearsol, Jim; Jarris, Paul

2012-01-01

There were 3 specific objectives of this study. The first objective was to examine the progress of state/territorial health assessment, health improvement planning, performance management, and quality improvement (QI) activities at state/territorial health agencies and compare findings to the 2007 findings when available. A second objective was to examine respondent interest and readiness for national voluntary accreditation. A final objective was to explore organizational factors (eg, leadership and capacity) that may influence QI or accreditation readiness. Cross-sectional study. State and Territorial Public Health Agencies. Survey respondents were organizational leaders at State and Territorial Public Health Agencies. Sixty-seven percent of respondents reported having a formal performance management process in place. Approximately 77% of respondents reported a QI process in place. Seventy-three percent of respondents agreed or strongly agreed that they would seek accreditation and 36% agreed or strongly agreed that they would seek accreditation in the first 2 years of the program. In terms of accreditation prerequisites, a strategic plan was most frequently developed, followed by a state/territorial health assessment and health improvement plan, respectively. Advancements in the practice and applied research of QI in state public health agencies are necessary steps for improving performance. In particular, strengthening the measurement of the QI construct is essential for meaningfully assessing current practice patterns and informing future programming and policy decisions. Continued QI training and technical assistance to agency staff and leadership is also critical. Accreditation may be the pivotal factor to strengthen both QI practice and research. Respondent interest in seeking accreditation may indicate the perceived value of accreditation to the agency.

Public health services and systems research: current state of finance research.

Science.gov (United States)

Ingram, Richard C; Bernet, Patrick M; Costich, Julia F

2012-11-01

There is a growing recognition that the US public health system should strive for efficiency-that it should determine the optimal ways to utilize limited resources to improve and protect public health. The field of public health finance research is a critical part of efforts to understand the most efficient ways to use resources. This article discusses the current state of public health finance research through a review of public health finance literature, chronicles important lessons learned from public health finance research to date, discusses the challenges faced by those seeking to conduct financial research on the public health system, and discusses the role of public health finance research in relation to the broader endeavor of Public Health Services and Systems Research.

Alternative mechanisms of state public health institutions financing in Ukraine

Directory of Open Access Journals (Sweden)

Hural, Anastasiya

2011-05-01

Full Text Available BACKGROUND. The main source of state public health institutions financing in Ukraine is budgetary funding. In order to overcome the underfunding, the idea of multichannel health financing was proposed in the late 1990s. The main forms of extrabudgetary financial support of public health institutions in Ukraine are voluntary health insurance, non-profit self-financing, charity and sponsorship. The study aims to deeper understand the nature of alternative financing mechanisms of state public health institutions in Ukraine and peculiarities of their use in practice.METHODS. The proposed study is exploratory. Case-study was selected as research method. Nine unstructured interviews were conducted in six health care facilities that have agreed to participate in the study. All studied facilities were in-patient.RESULTS. The sources of financial revenues of the studied institutions were as follows: reimbursement for treatment of insured patients, reimbursement for treatment of sickness funds members, payments for services (medical examinations, counseling, transportation to the hospital, rental of premises, payment for internship from the students of paid forms of medical education, charitable contributions, contracts with companies, contracts with private clinics based in public institutions’ premises (limited liability companies, private entrepreneurs, sponsorship, grants, gifts, payments for services for foreigners, and in-kind revenues. Major health facilities expenditures were the following: salaries (not covered from extrabudgetary revenues; ranged from 70% to 92% of the funds provided to the institutions from state (municipal, regional budget, energy carriers (partially covered from extrabudgetary funds, patients nutrition, medicines, materials, household expenditures, reparation of premises, and purchase of equipment (mostly covered from extrabudgetary revenues. In the studied cases, funds raised by alternative funding mechanisms amounted from

The Sustanability of Public Finance in New Members States of European Union

Directory of Open Access Journals (Sweden)

Adrian INCEU

2011-10-01

Full Text Available The issue of public finance sustainability is very important for all EU member states in the actual context after the economic crisis. This article makes an analysis of the sustainability of public finances for the new member states (which joined EU in 2004 and 2007. Firstly, we try to analyze the impact of the economic crisis on public finances sustainability. The sustainability of public finances can be reflected through the level of public debt and budget deficit for a country. For this reason the article presents the evolution of budget deficits for NMS 12 before and after the recent economic crisis. Based on the econometric regression the correlation between economic growth rate (indicator used for measuring the economic evolution and the budget deficit is revealed. Results for Romania and NMS 12 are quite similar; fact that tells us that the status of public finances is following the same trend in Romania as in the NMS 12.

Availability of ICTs in public libraries in North Central states of Nigeria

African Journals Online (AJOL)

This scenario prompted the researchers to examine the situation of ICTs provision in public libraries in North Central States of Nigeria. Public libraries were del iberately selected for this study because of their importance to the general public (the peoples' university) in Nigeria. The study is predominantly qualitative as most ...

A reaction time advantage for calculating beliefs over public representations signals domain specificity for 'theory of mind'.

Science.gov (United States)

Cohen, Adam S; German, Tamsin C

2010-06-01

In a task where participants' overt task was to track the location of an object across a sequence of events, reaction times to unpredictable probes requiring an inference about a social agent's beliefs about the location of that object were obtained. Reaction times to false belief situations were faster than responses about the (false) contents of a map showing the location of the object (Experiment 1) and about the (false) direction of an arrow signaling the location of the object (Experiment 2). These results are consistent with developmental, neuro-imaging and neuropsychological evidence that there exist domain specific mechanisms within human cognition for encoding and reasoning about mental states. Specialization of these mechanisms may arise from either core cognitive architecture or via the accumulation of expertise in the social domain.

Audit the effectiveness of the electronic system of public (state) procurement

OpenAIRE

Pysmenna, М.

2017-01-01

The study deals with the methodology of the audit the effectiveness of e-environment for public procurement. The purpose of this paper is deepening theoretical and methodological framework for auditing electronic systems for public (government) procurement. Research methods included analysis of legislation in the area of procurement, monitoring of individual transactions of public (state) procurement, interview with the responsible persons of budgetary funds on the assessment of the effective...

Extent of reference services to users in Ebonyi State Public Libraary ...

African Journals Online (AJOL)

Users are very satisfied with the extent of reference services provided to them by the public library studied. Findings further show that the reference section of Ebonyi State Public Library, Abakiliki is faced with the problems of inadequate reading space, equipment and furniture, reference information sources, unconducive ...

SH2 Domain Histochemistry.

Science.gov (United States)

Buhs, Sophia; Nollau, Peter

2017-01-01

Among posttranslational modifications, the phosphorylation of tyrosine residues is a key modification in cell signaling. Because of its biological importance, characterization of the cellular state of tyrosine phosphorylation is of great interest. Based on the unique properties of endogenously expressed SH2 domains recognizing tyrosine phosphorylated signaling proteins with high specificity we have developed an alternative approach, coined SH2 profiling, enabling us to decipher complex patterns of tyrosine phosphorylation in various normal and cancerous tissues. So far, SH2 profiling has largely been applied for the analysis of protein extracts with the limitation that information on spatial distribution and intensity of tyrosine phosphorylation within a tissue is lost. Here, we describe a novel SH2 domain based strategy for differential characterization of the state of tyrosine phosphorylation in formaldehyde-fixed and paraffin-embedded tissues. This approach demonstrates that SH2 domains may serve as very valuable tools for the analysis of the differential state of tyrosine phosphorylation in primary tissues fixed and processed under conditions frequently applied by routine pathology laboratories.

Utah Public Education Funding: The Fiscal Impact of School Choice. School Choice Issues in the State

Science.gov (United States)

Aud, Susan

2007-01-01

This study examines Utah's funding system for public education and provides an analysis of the fiscal impact of allowing parents to use a portion of their child's state education funding to attend a school of their choice, public or private. Like many states, Utah is facing pressure to improve its system of public education funding. The state's…

State equation approximation of transfer matrices and its application to the phase domain calculation of electromagnetic transients

International Nuclear Information System (INIS)

Soysal, A.O.; Semlyen, A.

1994-01-01

A general methodology is presented for the state equation approximation of a multiple input-output linear system from transfer matrix data. A complex transformation matrix, obtained by eigen analysis at a fixed frequency, is used for diagonalization of the transfer matrix over the whole frequency range. A scalar estimation procedure is applied for identification of the modal transfer functions. The state equations in the original coordinates are obtained by inverse transformation. An iterative Gauss-Newton refinement process is used to reduce the overall error of the approximation. The developed methodology is applied to the phase domain modeling of untransposed transmission lines. The approach makes it possible to perform EMTP calculations directly in the phase domain. This results in conceptual simplification and savings in computation time since modal transformations are not needed in the sequences of the transient analysis. The presented procedure is compared with the conventional modal approach in terms of accuracy and computation time

Single-domain versus two-domain configuration in thin ferromagnetic prisms

International Nuclear Information System (INIS)

Pini, Maria Gloria; Politi, Paolo

2007-01-01

Thin ferromagnetic elements in the form of rectangular prisms are theoretically investigated in order to study the transition from single-domain to two-domain state, with changing the in-plane aspect ratio p. We address two main questions: first, how general is the transition; second, how the critical value p c depends on the physical parameters. We use two complementary methods: discrete-lattice calculations and a micromagnetic continuum approach. Ultrathin films do not appear to split in two domains. Instead, thicker films may undergo the above transition. We have used the continuum approach to analyze recent magnetic force microscopy observations in 30nm-thick patterned permalloy elements, finding a good agreement for p c

Medical police and the nanny state: public health versus private autonomy.

Science.gov (United States)

Baron, Jeremy Hugh

2006-07-01

Rome tried to increase both the numbers of its people and their well-being, and hence their wealth, but it was not until the 16th century that European rulers were urged to achieve these aims by the power of the state to enforce public health. By the 17th century, absolutist states such as France, Austria and especially Germany had created an administrative profession of enlightened despotism, with medical police to encourage healthy and thus wealth-producing citizens. Johann Peter Frank (1745-1821) was the profession's exemplar with his 6,262 page System einer vollstländigen medischiner Polizey, leading to comprehensive public health legislation in German-speaking states, followed by more libertarian countries such as Britain and the United States. However, controversy continues on the role of government in trying to save its citizens, and especially their children, from harming themselves and/or others by their actions and omissions.

DC-SIGN neck domain is a pH-sensor controlling oligomerization: SAXS and hydrodynamic studies of extracellular domain.

Science.gov (United States)

Tabarani, Georges; Thépaut, Michel; Stroebel, David; Ebel, Christine; Vivès, Corinne; Vachette, Patrice; Durand, Dominique; Fieschi, Franck

2009-08-07

DC-SIGN is a C-type lectin receptor of dendritic cells and is involved in the early stages of numerous infectious diseases. DC-SIGN is organized into a tetramer enabling multivalent interaction with pathogens. Once formed, the DC-SIGN-pathogen complex can be internalized into compartments of increasing acidity. We have studied the pH dependence of the oligomerization state and conformation of the entire extracellular domain and neck region. We present evidence for equilibrium between the monomeric and tetrameric states of the extracellular domain, which exhibits a marked dependence with respect to both pH and ionic strength. Using solution x-ray scattering we have obtained a molecular envelope of the extracellular domain in which a model has been built. Our results highlight the central role of the neck domain in the pH-sensitive control of the oligomerization state, in the extended conformation of the protein, and in carbohydrate recognition domain organization and presentation. This work opens new insight into the molecular mechanism of ligand release and points to new avenues to block the first step of this important infection pathway.

Health, civilization, and the state: a history of public health from ancient to modern times

National Research Council Canada - National Science Library

Porter, Dorothy

1999-01-01

... including: * * * * * * * pestilence, public order and morality in pre-modern times the Enlightenment and its effects public health and centralization in Victorian Britain localization of health care in the United States population issues and family welfare the rise of the classic welfare state and its health care policies attitudes towards public health in...

Professionalism in Public Relations Pedagogy: A Comparative Analysis of Public Relations Curricula among the United States, the United Kingdom, and South Korea

Science.gov (United States)

Chung, Wonjun; Choi, Jinbong

2012-01-01

Based on a concept of professionalism, this study analyzed and compared current public relations curricula of higher education among the United States, the United Kingdom, and South Korea. In terms of three educational orientations, results indicated that public relations education in the United States is the most balanced among theoretical,…

Librarian-Initiated Publications Discovery: How Do Digital Depository Librarians Discover and Select Web-Based Government Publications for State Digital Depositories?

Science.gov (United States)

Lin, Chi-Shiou; Eschenfelder, Kristin R.

2010-01-01

This paper reports on a study of librarian initiated publications discovery (LIPD) in U.S. state digital depository programs using the OCLC Digital Archive to preserve web-based government publications for permanent public access. This paper describes a model of LIPD processes based on empirical investigations of four OCLC DA-based digital…

An Overview of Public Domain Tools for Measuring the Sustainability of Environmental Remediation - 12060

Energy Technology Data Exchange (ETDEWEB)

Claypool, John E.; Rogers, Scott [AECOM, Denver, Colorado, 80202 (United States)

2012-07-01

their clients. When it comes to the public domain, Federal government agencies are spearheading the development of software tools to measure and report emissions of air pollutants (e.g., carbon dioxide, other greenhouse gases, criteria air pollutants); consumption of energy, water and natural resources; accident and safety risks; project costs and other economic metrics. Most of the tools developed for the Government are available to environmental practitioners without charge, so they are growing in usage and popularity. The key features and metrics calculated by the available public-domain tools for measuring the sustainability of environmental remediation projects share some commonalities but there are differences amongst the tools. The SiteWise{sup TM} sustainability tool developed for the Navy and US Army will be compared with the Sustainable Remediation Tool (SRT{sup TM}) developed for the US Air Force (USAF). In addition, the USAF's Clean Solar and Wind Energy in Environmental Programs (CleanSWEEP), a soon-to-be-released tool for evaluating the economic feasibility of utilizing renewal energy for powering remediation systems will be described in the paper. (authors)

Structure characterization of the central repetitive domain of high molecular weight gluten proteins .2. Characterization in solution and in the dry state

NARCIS (Netherlands)

van Dijk, A.A.; De Boef, E.; Bekkers, A.; van Wijk, L.L.; van Swieten, E.; Hamer, R.J.; Robillard, G.T.

The structure of the central repetitive domain of high molecular weight (HMW) wheat gluten proteins was characterized in solution and in the dry state using HMW proteins Bx6 and Bx7 and a subcloned, bacterially expressed part of the repetitive domain of HMW Dx5. Model studies of the HMW consensus

Public responses to radioactive wastes in the United States

International Nuclear Information System (INIS)

Kasperson, R.E.

1993-01-01

Whatever the actual public health and environmental risks posed by nuclear power and the disposal of radioactive wastes, they pale in comparison with what the public believes they are. There can be little doubt that members of the public perceive substantial dangers from such facilities and are intensely concerned about them. Intense concern is apparent in the controversy that has erupted not only in the United States but in many societies where search activities have been conducted for a radioactive or other hazardous waste disposal facility. It is also apparent in the findings from a significant accumulation of polls, surveys, attitude studies, and psychometric research as well as in direct experience in diverse countries in Europe, North America, and Asia. (author). 10 refs

Public Health and Solitary Confinement in the United States.

Science.gov (United States)

Cloud, David H; Drucker, Ernest; Browne, Angela; Parsons, Jim

2015-01-01

The history of solitary confinement in the United States stretches from the silent prisons of 200 years ago to today's supermax prisons, mechanized panopticons that isolate tens of thousands, sometimes for decades. We examined the living conditions and characteristics of the populations in solitary confinement. As part of the growing movement for reform, public health agencies have an ethical obligation to help address the excessive use of solitary confinement in jails and prisons in accordance with established public health functions (e.g., violence prevention, health equity, surveillance, and minimizing of occupational and psychological hazards for correctional staff). Public health professionals should lead efforts to replace reliance on this overly punitive correctional policy with models based on rehabilitation and restorative justice.

Public Health and Solitary Confinement in the United States

Science.gov (United States)

Drucker, Ernest; Browne, Angela; Parsons, Jim

2015-01-01

The history of solitary confinement in the United States stretches from the silent prisons of 200 years ago to today’s supermax prisons, mechanized panopticons that isolate tens of thousands, sometimes for decades. We examined the living conditions and characteristics of the populations in solitary confinement. As part of the growing movement for reform, public health agencies have an ethical obligation to help address the excessive use of solitary confinement in jails and prisons in accordance with established public health functions (e.g., violence prevention, health equity, surveillance, and minimizing of occupational and psychological hazards for correctional staff). Public health professionals should lead efforts to replace reliance on this overly punitive correctional policy with models based on rehabilitation and restorative justice. PMID:25393185

Public-private Partnership in the Context of Realisation of the State Financial Policy

Directory of Open Access Journals (Sweden)

Ostapenko Victoriia M.

2014-02-01

Full Text Available In the result of the study the article analyses modern tendencies of development of economy of Ukraine. It marks out problems connected with realisation of the state financial policy. It considers the essence of the state financial policy, its directions (such as budget-tax and monetary-credit, structural components and tasks. It emphasises the place of the public-private partnership as an instrument of realisation of the financial policy. It justifies tasks in the process of realisation of goals of the modern financial policy, which could be carried out with the help of the public-private partnership. The prospect of further studies in this direction is formation of practical recommendations on the use of the public-private partnership in the process of realisation of the state financial policy. Further improvement of the public-private partnership is connected with development of efficient mechanisms of its introduction and optimisation of its financial structure.

Informational Element of Power: The Role of Public Diplomacy in United States-Cuba Policy Implementation

National Research Council Canada - National Science Library

Andujar, Roberto C

2005-01-01

THESIS: The United States should reassess its Public Diplomacy strategy toward Cuba and the key role that Public Diplomacy plays in preparing the Cuban people to transition to a free and democratic state. RATIONALE...

The Role of Backbone Hydrogen Bonds in the Transition State for Protein Folding of a PDZ Domain.

Directory of Open Access Journals (Sweden)

Søren W. Pedersen

Full Text Available Backbone hydrogen bonds are important for the structure and stability of proteins. However, since conventional site-directed mutagenesis cannot be applied to perturb the backbone, the contribution of these hydrogen bonds in protein folding and stability has been assessed only for a very limited set of small proteins. We have here investigated effects of five amide-to-ester mutations in the backbone of a PDZ domain, a 90-residue globular protein domain, to probe the influence of hydrogen bonds in a β-sheet for folding and stability. The amide-to-ester mutation removes NH-mediated hydrogen bonds and destabilizes hydrogen bonds formed by the carbonyl oxygen. The overall stability of the PDZ domain generally decreased for all amide-to-ester mutants due to an increase in the unfolding rate constant. For this particular region of the PDZ domain, it is therefore clear that native hydrogen bonds are formed after crossing of the rate-limiting barrier for folding. Moreover, three of the five amide-to-ester mutants displayed an increase in the folding rate constant suggesting that the hydrogen bonds are involved in non-native interactions in the transition state for folding.

The Development of an Automated Book Catalog for the State and Urban Publications Collection at Mankato State College.

Science.gov (United States)

Smith, Susan B.; Lester, Daniel W.

The State and Urban Publications Collection at Mankato State College contains materials from state and local agencies on urban planning. By 1971, when the collection had grown to the point that its haphazard organization was decreasing its usefulness as a resource tool, the library and the Urban Studies Institute formulated an information…

C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels.

Directory of Open Access Journals (Sweden)

Chai Ann Ng

Full Text Available Kv11.1 potassium channels are important for regulation of the normal rhythm of the heartbeat. Reduced activity of Kv11.1 channels causes long QT syndrome type 2, a disorder that increases the risk of cardiac arrhythmias and sudden cardiac arrest. Kv11.1 channels are members of the KCNH subfamily of voltage-gated K(+ channels. However, they also share many similarities with the cyclic nucleotide gated ion channel family, including having a cyclic nucleotide-binding homology (cNBH domain. Kv11.1 channels, however, are not directly regulated by cyclic nucleotides. Recently, crystal structures of the cNBH domain from mEAG and zELK channels, both members of the KCNH family of voltage-gated potassium channels, revealed that a C-terminal β9-strand in the cNBH domain occupied the putative cyclic nucleotide-binding site thereby precluding binding of cyclic nucleotides. Here we show that mutations to residues in the β9-strand affect the stability of the open state relative to the closed state of Kv11.1 channels. We also show that disrupting the structure of the β9-strand reduces the stability of the inactivated state relative to the open state. Clinical mutations located in this β9-strand result in reduced trafficking efficiency, which suggests that binding of the C-terminal β9-strand to the putative cyclic nucleotide-binding pocket is also important for assembly and trafficking of Kv11.1 channels.

assessement of information resource of public libraries in rivers state

African Journals Online (AJOL)

Information Impact | Journal of Information and Knowledge Management

users, awareness of resources provided by public libraries in Rivers State is low, ... decision making, and culture development of individuals and social groups. ..... programmes, current affairs, fish production, human right, business, oil spillage,.

Assessing water availability over peninsular Malaysia using public domain satellite data products

International Nuclear Information System (INIS)

Ali, M I; Hashim, M; Zin, H S M

2014-01-01

Water availability monitoring is an essential task for water resource sustainability and security. In this paper, the assessment of satellite remote sensing technique for determining water availability is reported. The water-balance analysis is used to compute the spatio-temporal water availability with main inputs; the precipitation and actual evapotranspiration rate (AET), both fully derived from public-domain satellite products of Tropical Rainfall Measurement Mission (TRMM) and MODIS, respectively. Both these satellite products were first subjected to calibration to suit corresponding selected local precipitation and AET samples. Multi-temporal data sets acquired 2000-2010 were used in this study. The results of study, indicated strong agreement of monthly water availability with the basin flow rate (r 2 = 0.5, p < 0.001). Similar agreements were also noted between the estimated annual average water availability with the in-situ measurement. It is therefore concluded that the method devised in this study provide a new alternative for water availability mapping over large area, hence offers the only timely and cost-effective method apart from providing comprehensive spatio-temporal patterns, crucial in water resource planning to ensure water security

Structure characterization of the central repetitive domain of high molecular weight gluten proteins. II. Characterization in solution and in the dry state

OpenAIRE

Dijk, Alard A. van; Boef, Esther de; Bekkers, August; Wijk, Lourens L. van; Swieten, Eric van; Hamer, Rob J.; Robillard, George T.

1997-01-01

The structure of the central repetitive domain of high molecular weight HMW) wheat gluten proteins was characterized in solution and in the dry state using HMW proteins Bx6 and Bx7 and a subcloned, bacterially expressed part of the repetitive domain of HMW Dx5. Model studies of the HMW consensus peptides PGQGQQ and GYYPTSPQQ formed the basis for the data analysis (van Dijk AA et al., 1997, Protein Sci 6:637-648). In solution, the repetitive domain contained a continuous nonoverlapping series ...

State Disinvestment, Technologies of Choice and "Fitting In": Neoliberal Transformations in US Public Education

Science.gov (United States)

Convertino, Christina

2017-01-01

Given state cuts to US public education, overcrowding and underfunding in urban district schools continue to grow. Yet, how parents understand the role of state disinvestment on underfunded and overcrowded public schools remains relatively unexamined. Drawing from an ethnographic study of school choice in Arizona, I explore how a group of white…

1H, 15N and 13C assignments of domain 5 of Dictyostelium discoideum gelation factor (ABP-120) in its native and 8M urea-denatured states.

Science.gov (United States)

Hsu, Shang-Te Danny; Cabrita, Lisa D; Christodoulou, John; Dobson, Christopher M

2009-06-01

The gelation factor from Dictyostelium discoideum (ABP-120) is an actin binding protein consisting of six immunoglobulin (Ig) domains in the C-terminal rod domain. We have recently used the pair of domains 5 and 6 of ABP-120 as a model system for studying multi-domain nascent chain folding on the ribosome. Here we present the NMR assignments of domain 5 in its native and 8M urea-denatured states.

75 FR 66054 - Nondiscrimination on the Basis of Disability in State and Local Government Services, Public...

Science.gov (United States)

2010-10-27

... Nondiscrimination on the Basis of Disability in State and Local Government Services, Public Accommodations and in... of Disability; Accessibility of Web Information and Services of State and Local Government Entities and Public Accommodations; Nondiscrimination on the Basis of Disability in State and Local Government...

A Comparative Analysis of Internal Communication and Public Relations Audits. State of the Art.

Science.gov (United States)

Dozier, David M.; Hellweg, Susan A.

A review of current literature regarding the state of the art in the conduct of internal communication and public relations audits by public relations practitioners reveals that these two related measurement activities are of considerable importance to the practice of public relations. Public relations audits are concerned with exploratory…

Islamophobia and Public Health in the United States.

Science.gov (United States)

Samari, Goleen

2016-11-01

Anti-Muslim sentiments are increasingly common globally and in the United States. The recent rise in Islamophobia calls for a public health perspective that considers the stigmatized identity of Muslim Americans and health implications of Islamophobic discrimination. Drawing on a stigma, discrimination, and health framework, I expand the dialogue on the rise of Islamophobia to a discussion of how Islamophobia affects the health of Muslim Americans. Islamophobia can negatively influence health by disrupting several systems-individual (stress reactivity and identity concealment), interpersonal (social relationships and socialization processes), and structural (institutional policies and media coverage). Islamophobia deserves attention as a source of negative health outcomes and health disparities. Future public health research should explore the multilevel and multidimensional pathways between Islamophobia and population health.

Basis adaptation and domain decomposition for steady-state partial differential equations with random coefficients

Energy Technology Data Exchange (ETDEWEB)

Tipireddy, R.; Stinis, P.; Tartakovsky, A. M.

2017-12-01

We present a novel approach for solving steady-state stochastic partial differential equations (PDEs) with high-dimensional random parameter space. The proposed approach combines spatial domain decomposition with basis adaptation for each subdomain. The basis adaptation is used to address the curse of dimensionality by constructing an accurate low-dimensional representation of the stochastic PDE solution (probability density function and/or its leading statistical moments) in each subdomain. Restricting the basis adaptation to a specific subdomain affords finding a locally accurate solution. Then, the solutions from all of the subdomains are stitched together to provide a global solution. We support our construction with numerical experiments for a steady-state diffusion equation with a random spatially dependent coefficient. Our results show that highly accurate global solutions can be obtained with significantly reduced computational costs.

78 FR 39765 - Notice of Proposed Classification of Public Lands/Minerals for State Indemnity Selection, Colorado

Science.gov (United States)

2013-07-02

... Proposed Classification of Public Lands/Minerals for State Indemnity Selection, Colorado AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Proposed Classification. SUMMARY: The Colorado State Board... public lands and mineral estate in lieu of lands to which the State was entitled but did not receive...

Factors associated with local public health agency participation in obesity prevention in southern States.

Science.gov (United States)

Hatala, Jeffrey J; Fields, Tina T

2015-05-01

Obesity rates in the southern US states are higher than in other states. Historically, large-scale community-based interventions in the United States have not proven successful. With local public health agencies (LPHAs) tasked with prevention, their role in obesity prevention is important, yet little research exists regarding what predicts the participation of LPHAs. Cross-sectional data from the 2008 National Association of City and County Health Officials profile study and two public health conceptual frameworks were used to assess structural and environmental predictors of LPHA participation in obesity prevention. The predictors were compared between southern and nonsouthern states. Univariate and weighted logistic regressions were performed. Analysis revealed that more LPHAs in southern states were engaged in nearly all of the 10 essential public health functions related to obesity prevention compared with nonsouthern states. Presence of community-based organizations and staffing levels were the only significant variables in two of the six logistic regression models. This study provides insights into the success rates of the obesity prevention efforts of LPHAs in southern and nonsouthern states. Future research is needed to understand why and how certain structural elements and any additional factors influence LPHA participation in obesity prevention.

How Much Do We Spend? Creating Historical Estimates of Public Health Expenditures in the United States at the Federal, State, and Local Levels.

Science.gov (United States)

Leider, Jonathon P; Resnick, Beth; Bishai, David; Scutchfield, F Douglas

2018-04-01

The United States has a complex governmental public health system. Agencies at the federal, state, and local levels all contribute to the protection and promotion of the population's health. Whether the modern public health system is well situated to deliver essential public health services, however, is an open question. In some part, its readiness relates to how agencies are funded and to what ends. A mix of Federalism, home rule, and happenstance has contributed to a siloed funding system in the United States, whereby health agencies are given particular dollars for particular tasks. Little discretionary funding remains. Furthermore, tracking how much is spent, by whom, and on what is notoriously challenging. This review both outlines the challenges associated with estimating public health spending and explains the known sources of funding that are used to estimate and demonstrate the value of public health spending.

Bit-Oriented Quantum Public-Key Cryptosystem Based on Bell States

Science.gov (United States)

Wu, WanQing; Cai, QingYu; Zhang, HuanGuo; Liang, XiaoYan

2018-06-01

Quantum public key encryption system provides information confidentiality using quantum mechanics. This paper presents a quantum public key cryptosystem ( Q P K C) based on the Bell states. By H o l e v o' s theorem, the presented scheme provides the security of the secret key using one-wayness during the QPKC. While the QPKC scheme is information theoretic security under chosen plaintext attack ( C P A). Finally some important features of presented QPKC scheme can be compared with other QPKC scheme.

Radiological emergencies due to postulated events of melted radioactive material mixed in steel reaching public domain

International Nuclear Information System (INIS)

Meena, T.R.; Anoj Kumar; Patra, R.P.; Vikas; Patil, S.S.; Chatterjee, M.K.; Sharma, Ranjit; Murali, S.

2014-01-01

National level response mechanism is developed at emergency response centres of DAE (DAE-ERCs) at 22 different locations spread all over the country and National Disaster Response Forces with National Disaster Management Authority (NDMA). ERCs are equipped with radiation monitors, radionuclide identifinders, Personnel Radiation Dosimeters (PRD) with monitoring capabilities of the order of tens of nGy/h (μR/hr) above the radiation background at any suspected locations. Even if small amounts of radioactive material is smuggled and brought in some other form into public domain, ERCs are capable to detect, identify and segregate the radioactive material from any inactive scrap. DAE-ERCs have demonstrated their capability in source search, detection, identification and recovery during the radiological emergency at Mayapuri, New Delhi

Radiological emergencies due to postulated events of melted radioactive material mixed in steel reaching public domain

Energy Technology Data Exchange (ETDEWEB)

Meena, T. R.; Kumar, Anoj; Patra, R. P.; Vikas,; Patil, S. S.; Chatterjee, M. K.; Sharma, Ranjit; Murali, S., E-mail: tejram@barc.gov.in [Radiation Safety Systems Division, Bhabha Atomic Research Centre, Mumbai (India)

2014-07-01

National level response mechanism is developed at emergency response centres of DAE (DAE-ERCs) at 22 different locations spread all over the country and National Disaster Response Forces with National Disaster Management Authority (NDMA). ERCs are equipped with radiation monitors, radionuclide identifinders, Personnel Radiation Dosimeters (PRD) with monitoring capabilities of the order of tens of nGy/h (μR/hr) above the radiation background at any suspected locations. Even if small amounts of radioactive material is smuggled and brought in some other form into public domain, ERCs are capable to detect, identify and segregate the radioactive material from any inactive scrap. DAE-ERCs have demonstrated their capability in source search, detection, identification and recovery during the radiological emergency at Mayapuri, New Delhi.

Finding the Secret of Image Saliency in the Frequency Domain.

Science.gov (United States)

Li, Jia; Duan, Ling-Yu; Chen, Xiaowu; Huang, Tiejun; Tian, Yonghong

2015-12-01

There are two sides to every story of visual saliency modeling in the frequency domain. On the one hand, image saliency can be effectively estimated by applying simple operations to the frequency spectrum. On the other hand, it is still unclear which part of the frequency spectrum contributes the most to popping-out targets and suppressing distractors. Toward this end, this paper tentatively explores the secret of image saliency in the frequency domain. From the results obtained in several qualitative and quantitative experiments, we find that the secret of visual saliency may mainly hide in the phases of intermediate frequencies. To explain this finding, we reinterpret the concept of discrete Fourier transform from the perspective of template-based contrast computation and thus develop several principles for designing the saliency detector in the frequency domain. Following these principles, we propose a novel approach to design the saliency detector under the assistance of prior knowledge obtained through both unsupervised and supervised learning processes. Experimental results on a public image benchmark show that the learned saliency detector outperforms 18 state-of-the-art approaches in predicting human fixations.

Job Satisfaction and Expected Turnover Among Federal, State, and Local Public Health Practitioners.

Science.gov (United States)

Leider, Jonathon P; Harper, Elizabeth; Shon, Ji Won; Sellers, Katie; Castrucci, Brian C

2016-10-01

To use data on the governmental public health workforce to examine demographics and elucidate drivers of job satisfaction and intent to leave one's organization. Using microdata from the 2014 Federal Employee Viewpoint Survey and 2014 Public Health Workforce Interests and Needs Survey, we drew comparisons between federal, state, and local public health staff. We fitted logistic regressions to examine correlates of both job satisfaction and intent to leave one's organization within the coming year. Correlates of job satisfaction included pay satisfaction, organizational support, and employee involvement. Approximately 40% of federal, state, and local staff said they were either considering leaving their organization in the next year or were planning to retire by 2020. Public health practitioners largely like their jobs, but many are dissatisfied with their pay and are considering working elsewhere. More should be done to understand the determinants of job satisfaction and how to successfully retain high-quality staff. Public health is at a crossroads. Significant turnover is expected in the coming years. Retention efforts should engage staff across all levels of public health.

Detecting and monitoring water stress states in maize crops using spectral ratios obtained in the photosynthetic domain

Science.gov (United States)

Baranoski, Gladimir V. G.; Van Leeuwen, Spencer R.

2017-07-01

The reliable detection and monitoring of changes in the water status of crops composed of plants like maize, a highly adaptable C4 species in large demand for both food and biofuel production, are longstanding remote sensing goals. Existing procedures employed to achieve these goals rely predominantly on the spectral signatures of plant leaves in the infrared domain where the light absorption within the foliar tissues is dominated by water. It has been suggested that such procedures could be implemented using subsurface reflectance to transmittance ratios obtained in the visible (photosynthetic) domain with the assistance of polarization devices. However, the experiments leading to this proposition were performed on detached maize leaves, which were not influenced by the whole (living) plant's adaptation mechanisms to water stress. In this work, we employ predictive simulations of light-leaf interactions in the photosynthetic domain to demonstrate that the living specimens' physiological responses to dehydration stress should be taken into account in this context. Our findings also indicate that a reflectance to transmittance ratio obtained in the photosynthetic domain at a lower angle of incidence without the use of polarization devices may represent a cost-effective alternative for the assessment of water stress states in maize crops.

Comparison of montreal cognitive assessment and mini-mental state examination in evaluating cognitive domain deficit following aneurysmal subarachnoid haemorrhage.

Directory of Open Access Journals (Sweden)

George Kwok Chu Wong

Full Text Available Cognitive deficits are common after aneurysmal subarachnoid haemorrhage (aSAH, and clinical evaluation is important for their management. Our hypothesis was that the Montreal Cognitive Assessment (MoCa is superior to the Mini-Mental State Examination (MMSE in screening for cognitive domain deficit in aSAH patients.We carried out a prospective observational and diagnostic accuracy study on Hong Kong aSAH patients aged 21 to 75 years who had been admitted within 96 hours of ictus. The domain-specific neuropsychological assessment battery, the MoCA and MMSE were administered 2-4 weeks and 1 year after ictus. A cognitive domain deficit was defined as a cognitive domain z score <-1.65 (below the fifth percentile. Cognitive impairment was defined as two or more cognitive domain deficits. The study is registered at ClinicalTrials.gov of the US National Institutes of Health (NCT01038193.Both the MoCA and the MMSE were successful in differentiating between patients with and without cognitive domain deficits and cognitive impairment at both assessment periods. At 1 year post-ictus, the MoCA produced higher area under the curve scores for cognitive impairment than the MMSE (MoCA, 0.92; 95% CI, 0.83 to 0.97 versus MMSE, 0.77; 95% CI, 0.66 to 0.83, p = 0.009.Cognitive domain deficits and cognitive impairment in patients with aSAH can be screened with the MoCA in both the subacute and chronic phases.

A taxonomy of state public health preparedness units: an empirical examination of organizational structure.

Science.gov (United States)

Menachemi, Nir; Yeager, Valerie A; Duncan, W Jack; Katholi, Charles R; Ginter, Peter M

2012-01-01

State public health preparedness units (SPHPUs) were developed in response to federal funding to improve response to disasters: a responsibility that had not traditionally been within the purview of public health. The SPHPUs were created within the existing public health organizational structure, and their placement may have implications for how the unit functions, how communication takes place, and ultimately how well the key responsibilities are performed. This study empirically identifies a taxonomy of similarly structured SPHPUs and examines whether this structure is associated with state geographic, demographic, and threat-vulnerability characteristics. Data representing each SPHPU were extracted from publically available sources, including organizational charts and emergency preparedness plans for 2009. A cross-sectional segmentation analysis was conducted of variables representing structural attributes. Fifty state public health departments. Variables representing "span of control" and "hierarchal levels" were extracted from organizational charts. Structural "complexity" and "centralization" were extracted from state emergency preparedness documents and other secondary sources. On average, 6.6 people report to the same manager as the SPHPU director; 2.1 levels separate the SPHPU director from the state health officer; and a mean of 13.5 agencies collaborate with SPHPU during a disaster. Despite considerable variability in how SPHPUs had been structured, results of the cluster and principal component analysis identified 7 similarly structured groups. Neither the taxonomic groups nor the individual variables representing structure were found to be associated with state characteristics, including threat vulnerabilities. Our finding supports the hypothesis that SPHPUs are seemingly inadvertently (eg, not strategically) organized. This taxonomy provides the basis for which future research can examine how SPHPU structure relates to performance measures and

DEFINITION OF PUBLIC SERVICE OBLIGATION POTENTIAL IN THE NEW EU MEMBER STATES

Directory of Open Access Journals (Sweden)

Martin HROMÁDKA

2017-04-01

Full Text Available This paper deals with public service obligation, a form of state aid that applies to air services. The paper first provides general information on the European legislation applying to this form of state aid, and elaborates the legal framework and general principles. The second part is dedicated to a comparison of a similar subsidizing programme in the USA and Australia. An examination of current imposed public service obligation routes in Europe is provided in the following section. The coefficients defining the number of imposed PSO routes per various geo-economic variables have been defined.

Mutations in the FMN domain modulate MCD spectra of the heme site in the oxygenase domain of inducible nitric oxide synthase.

Science.gov (United States)

Sempombe, Joseph; Elmore, Bradley O; Sun, Xi; Dupont, Andrea; Ghosh, Dipak K; Guillemette, J Guy; Kirk, Martin L; Feng, Changjian

2009-05-27

The nitric oxide synthase (NOS) output state for NO production is a complex of the flavin mononucleotide (FMN)-binding domain and the heme domain, and thereby it facilitates the interdomain electron transfer from the FMN to the catalytic heme site. Emerging evidence suggests that interdomain FMN-heme interactions are important in the formation of the output state because they guide the docking of the FMN domain to the heme domain. In this study, notable effects of mutations in the adjacent FMN domain on the heme structure in a human iNOS bidomain oxygenase/FMN construct have been observed by using low-temperature magnetic circular dichroism (MCD) spectroscopy. The comparative MCD study of wild-type and mutant proteins clearly indicates that a properly docked FMN domain contributes to the observed L-Arg perturbation of the heme MCD spectrum in the wild-type protein and that the conserved surface residues in the FMN domain (E546 and E603) play key roles in facilitating a productive alignment of the FMN and heme domains in iNOS.

76 FR 366 - Public Water Supply Supervision Program; Program Revision for the State of Washington

Science.gov (United States)

2011-01-04

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9247-4] Public Water Supply Supervision Program; Program... State Public Water Supply Supervision Primacy Program. Washington has adopted a definition for public water system that is analogous to EPA's definition of public water system, and has adopted regulations...

On Domain Registries and Website Content

DEFF Research Database (Denmark)

Schwemer, Sebastian Felix

2018-01-01

such as Internet access service providers, hosting platforms, and websites that link to content. This article shows that in recent years, however, that the (secondary) liability of domain registries and registrars, and more specifically country code top-level domain registries (ccTLDs) for website content, has...... been tested in several EU Member States. The article investigates tendencies in the national lower-court jurisprudence and explores to what extent the liability exemption regime of the E-Commerce Directive applies to domain registries. The analysis concludes that whereas domain registries fall under...

Allocation of ventilators in a public health disaster.

Science.gov (United States)

Powell, Tia; Christ, Kelly C; Birkhead, Guthrie S

2008-03-01

In a public health emergency, many more patients could require mechanical ventilators than can be accommodated. To plan for such a crisis, the New York State Department of Health and the New York State Task Force on Life and the Law convened a workgroup to develop ethical and clinical guidelines for ventilator triage. The workgroup crafted an ethical framework including the following components: duty to care, duty to steward resources, duty to plan, distributive justice, and transparency. Incorporating the ethical framework, the clinical guidelines propose both withholding and withdrawing ventilators from patients with the highest probability of mortality to benefit patients with the highest likelihood of survival. Triage scores derive from the sepsis-related organ failure assessment system, which assigns points based on function in 6 basic medical domains. Triage may not be implemented by a facility without clear permission from public health authorities. New York State released the draft guidelines for public comment, allowing for revision to reflect both community values and medical innovation. This ventilator triage system represents a radical shift from ordinary standards of care, and may serve as a model for allocating other scarce resources in disasters.

Web Syndication Approaches for Sharing Primary Data in "Small Science" Domains

Directory of Open Access Journals (Sweden)

Eric C Kansa

2010-06-01

Full Text Available In some areas of science, sophisticated web services and semantics underlie "cyberinfrastructure". However, in "small science" domains, especially in field sciences such as archaeology, conservation, and public health, datasets often resist standardization. Publishing data in the small sciences should embrace this diversity rather than attempt to corral research into "universal" (domain standards. A growing ecosystem of increasingly powerful Web syndication based approaches for sharing data on the public Web can offer a viable approach. Atom Feed based services can be used with scientific collections to identify and create linkages across different datasets, even across disciplinary boundaries without shared domain standards.

A Theoretical and Conceptual Approach to Public Policy , State Models and Brazilian Judiciary Practice

Directory of Open Access Journals (Sweden)

Andrea Abrahão Costa

2016-05-01

Full Text Available Since the consolidation of Western democratic regimes, the issue of public policy takes greater prominence in the academic setting and was taken as an object of study by different branches of knowledge. In the present paper attempts to map the various concepts built for public policy, in order to try to answer three questions: what would be the public policy, which the theories that could be used to give them support and what historical context discussion would have appeared. In addition, it seeks to systematize the interaction between public policy and law from three aspects: their integration in the context of the Constitutional State, legalization of phenomenon of emergence of the policy and its relationship with the notions that inform the public governance. It is stated, finally, that the presented questioning aims to contribute to the start of construction of a proper legal analysis of the field of public policy.

An information theory framework for dynamic functional domain connectivity.

Science.gov (United States)

Vergara, Victor M; Miller, Robyn; Calhoun, Vince

2017-06-01

Dynamic functional network connectivity (dFNC) analyzes time evolution of coherent activity in the brain. In this technique dynamic changes are considered for the whole brain. This paper proposes an information theory framework to measure information flowing among subsets of functional networks call functional domains. Our method aims at estimating bits of information contained and shared among domains. The succession of dynamic functional states is estimated at the domain level. Information quantity is based on the probabilities of observing each dynamic state. Mutual information measurement is then obtained from probabilities across domains. Thus, we named this value the cross domain mutual information (CDMI). Strong CDMIs were observed in relation to the subcortical domain. Domains related to sensorial input, motor control and cerebellum form another CDMI cluster. Information flow among other domains was seldom found. Other methods of dynamic connectivity focus on whole brain dFNC matrices. In the current framework, information theory is applied to states estimated from pairs of multi-network functional domains. In this context, we apply information theory to measure information flow across functional domains. Identified CDMI clusters point to known information pathways in the basal ganglia and also among areas of sensorial input, patterns found in static functional connectivity. In contrast, CDMI across brain areas of higher level cognitive processing follow a different pattern that indicates scarce information sharing. These findings show that employing information theory to formally measured information flow through brain domains reveals additional features of functional connectivity. Copyright © 2017 Elsevier B.V. All rights reserved.

The public information aspects of nuclear regulatory inspection in the United States

International Nuclear Information System (INIS)

Volgenau, E.

1977-01-01

The public information aspects of the regulation of nuclear power present a unique set of problems. Not only must the regulators communicate often complex technical information to the public, they must also assure the public, the press and the legislative bodies of the adequacy of the regulatory process and the safety of power plant operations. The United States Nuclear Regulatory Commission (NRC), recognizing the importance of a continuing, open dialogue with the public, has placed particular emphasis on informing the public of its operations. NRC's experiences have been both good and bad. On balance, however, the NRC believes it is following the best course by conducting its operations openly and candidly. (author)

75 FR 27743 - Publication of State Plan Pursuant to the Help America Vote Act

Science.gov (United States)

2010-05-18

... ELECTION ASSISTANCE COMMISSION Publication of State Plan Pursuant to the Help America Vote Act... previously submitted by New Mexico. DATES: This notice is effective upon publication in the Federal Register... 27744

Public Investment and Economic Growth in The European Union Member States

Directory of Open Access Journals (Sweden)

Liliana DONATH

2009-06-01

Full Text Available The issue of public investments becamea very challenging subject for public decisionmakerssince it incorporates the question of stateperformance, the quality of public finance and theireffects on growth. The quality of public finance is amultidimensional concept. It may be regarded asrepresenting all the arrangements and operationsregarding the financial politics that sustain themacroeconomic objectives, particularly the longtermeconomic growth. Financial policies atEuropean level highlight the fact that a concentrationof the public expenses in areas that stimulate theeconomic growth and a more efficient use of thepublic resources are key methods for sustainingthe economic growth. The empirical proofs seem tosupport the assumption according to which certaintypes of public expenses can supply incentivesand other can negatively influence the economicgrowth. The paper tries to reveal the effects ofcapital spending on economic growth (GDP percapita for the European Union member states.The GDP per capita and the capital expenses(functional classification of public expenses -“COFOG” have been obtained by consideringthe Eurostat statistics, the measurement unit forboth variables is Euro, while the period of analysisis of 7 years (2000-2006.

Principals' Management of Conflicts in Public Secondary Schools in Ondo State, Nigeria: A Critical Survey

Science.gov (United States)

Adeyemi, T. O.

2009-01-01

This paper examined principals' management of conflicts in public secondary schools in Ondo State, Nigeria. As a descriptive survey, the study population comprised all the 281 public secondary schools in the State. Out of this population, a sample of 80 schools was drawn while 340 respondents (80 principals and 260 teachers) were selected through…

Hospitalization flow in the public and private systems in the state of Sao Paulo, Brazil.

Science.gov (United States)

Rocha, Juan Stuardo Yazlle; Monteiro, Rosane Aparecida; Moreira, Marizélia Leão

2015-01-01

OBJECTIVE To describe the migration flows of demand for public and private hospital care among the health regions of the state of Sao Paulo, Brazil.METHODS Study based on a database of hospitalizations in the public and private systems of the state of Sao Paulo, Southeastern Brazil, in 2006. We analyzed data from 17 health regions of the state, considering people hospitalized in their own health region and those who migrated outwards (emigration) or came from other regions (immigration). The index of migration effectiveness of patients from both systems was estimated. The coverage (hospitalization coefficient) was analyzed in relation to the number of inpatient beds per population and the indexes of migration effectiveness.RESULTS The index of migration effectiveness applied to the hospital care demand flow allowed characterizing health regions with flow balance, with high emigration of public and private patients, and with high attraction of public and private patients.CONCLUSIONS There are differences in hospital care access and opportunities among health regions in the state of Sao Paulo, Brazil.

The Public Understanding of Assessment in Educational Reform in the United States

Science.gov (United States)

Brookhart, Susan M.

2013-01-01

The United States education system depends on legislation and funding at the federal, state and local levels. Public understanding of assessment therefore is important to educational reform in the USA. Educational reformers often invoke assessment information as a reason for reform, typically by citing unacceptable achievement on some measure or…

Delivery of public services in ethnic minority states: Gender equality ...

International Development Research Centre (IDRC) Digital Library (Canada)

Delivery of public services in ethnic minority states: Gender equality and decentralization in Myanmar. In 2017, to sustain Myanmar's democratic transition, IDRC and Global Affairs Canada ... and staff from the University of Toronto's Munk School of Global Affairs (Asia ... Ideas from the global climate change hotspot research.

SH2 domains: modulators of nonreceptor tyrosine kinase activity.

Science.gov (United States)

Filippakopoulos, Panagis; Müller, Susanne; Knapp, Stefan

2009-12-01

The Src homology 2 (SH2) domain is a sequence-specific phosphotyrosine-binding module present in many signaling molecules. In cytoplasmic tyrosine kinases, the SH2 domain is located N-terminally to the catalytic kinase domain (SH1) where it mediates cellular localization, substrate recruitment, and regulation of kinase activity. Initially, structural studies established a role of the SH2 domain stabilizing the inactive state of Src family members. However, biochemical characterization showed that the presence of the SH2 domain is frequently required for catalytic activity, suggesting a crucial function stabilizing the active state of many nonreceptor tyrosine kinases. Recently, the structure of the SH2-kinase domain of Fes revealed that the SH2 domain stabilizes the active kinase conformation by direct interactions with the regulatory helix alphaC. Stabilizing interactions between the SH2 and the kinase domains have also been observed in the structures of active Csk and Abl. Interestingly, mutations in the SH2 domain found in human disease can be explained by SH2 domain destabilization or incorrect positioning of the SH2. Here we summarize our understanding of mechanisms that lead to tyrosine kinase activation by direct interactions mediated by the SH2 domain and discuss how mutations in the SH2 domain trigger kinase inactivation.

Unsupervised domain adaptation techniques based on auto-encoder for non-stationary EEG-based emotion recognition.

Science.gov (United States)

Chai, Xin; Wang, Qisong; Zhao, Yongping; Liu, Xin; Bai, Ou; Li, Yongqiang

2016-12-01

In electroencephalography (EEG)-based emotion recognition systems, the distribution between the training samples and the testing samples may be mismatched if they are sampled from different experimental sessions or subjects because of user fatigue, different electrode placements, varying impedances, etc. Therefore, it is difficult to directly classify the EEG patterns with a conventional classifier. The domain adaptation method, which is aimed at obtaining a common representation across training and test domains, is an effective method for reducing the distribution discrepancy. However, the existing domain adaptation strategies either employ a linear transformation or learn the nonlinearity mapping without a consistency constraint; they are not sufficiently powerful to obtain a similar distribution from highly non-stationary EEG signals. To address this problem, in this paper, a novel component, called the subspace alignment auto-encoder (SAAE), is proposed. Taking advantage of both nonlinear transformation and a consistency constraint, we combine an auto-encoder network and a subspace alignment solution in a unified framework. As a result, the source domain can be aligned with the target domain together with its class label, and any supervised method can be applied to the new source domain to train a classifier for classification in the target domain, as the aligned source domain follows a distribution similar to that of the target domain. We compared our SAAE method with six typical approaches using a public EEG dataset containing three affective states: positive, neutral, and negative. Subject-to-subject and session-to-session evaluations were performed. The subject-to-subject experimental results demonstrate that our component achieves a mean accuracy of 77.88% in comparison with a state-of-the-art method, TCA, which achieves 73.82% on average. In addition, the average classification accuracy of SAAE in the session-to-session evaluation for all the 15 subjects

Progress in increasing electronic reporting of laboratory results to public health agencies--United States, 2013.

Science.gov (United States)

2013-09-27

Electronic reporting of laboratory results to public health agencies can improve public health surveillance for reportable diseases and conditions by making reporting more timely and complete. Since 2010, CDC has provided funding to 57 state, local, and territorial health departments through the Epidemiology and Laboratory Capacity for Infectious Diseases cooperative agreement to assist with improving electronic laboratory reporting (ELR) from clinical and public health laboratories to public health agencies. As part of this agreement, CDC and state and large local health departments are collaborating to monitor ELR implementation in the United States by developing data from each jurisdiction regarding total reporting laboratories, laboratories sending ELR by disease category and message format, and the number of ELR laboratory reports compared with the total number of laboratory reports. At the end of July 2013, 54 of the 57 jurisdictions were receiving at least some laboratory reports through ELR, and approximately 62% of 20 million laboratory reports were being received electronically, compared with 54% in 2012. Continued progress will require collaboration between clinical laboratories, laboratory information management system (LIMS) vendors, and public health agencies.

Budget Deficit And Public Debt - The Great Challenges For The Eu Member States

Directory of Open Access Journals (Sweden)

Lupu, Iulia

2010-12-01

Full Text Available The financial crises had a strong impact on the public finance sectors from European countries. Even if in 2007 they started from relative good fiscal positions, the public debt and the budgetary deficits considerably deteriorated and registered historic values in European Union. With all measures taken to stimulate the economy, is a very favourable scenario to return at the taxes level from 2007. The aggregate numbers regarding the deficit and public debt incline to disguise the different evolutions of the European Union member states. The strong deterioration of fiscal indicators is caused by the automat effect of the economic productivity and also by measures taken by the governments of the member states. The past experiences can help to evaluate the fiscal measures that must be adopted in order to reduce the public debt and the deficit, without having an universal solution for all countries. Very important is the existing context for the implementation of adopted measures.

The First Steps Towards Harmonizing Public Sector Accounting for European Union Member States

DEFF Research Database (Denmark)

Pontoppidan, Caroline Aggestam; Alijarde, Isabel Brusca

2016-01-01

This paper analyses the process that led the European Commission to the decision to develop European Public Sector Accounting Standards (EPSAS) for harmonizing public sector accounting practices within the European Union. The paper finds that there was limited scope in terms of stakeholder...... participation in the public consultation that served as a basis for the decision. In addition, the decision to adopt EPSAS for EU member states raises questions on the relationship between regional and global governance in the area of public sector accounting....

Corporal Punishment in Public Schools: Is the United States Out of Step?

Science.gov (United States)

McCarthy, Martha M.

2005-01-01

Few topics evoke more emotion than how to discipline children in public schools. And not many people are neutral in their views toward corporal punishment. Surprisingly, the United States stands almost alone on its position regarding the legality of corporal punishment. Among thirty-five industrialized countries, only the United States and the…

Relational conceptions of paternalism: a way to rebut nanny-state accusations and evaluate public health interventions.

Science.gov (United States)

Carter, S M; Entwistle, V A; Little, M

2015-08-01

'Nanny-state' accusations can function as powerful rhetorical weapons against interventions intended to promote public health. Public health advocates often lack effective rebuttals to these criticisms. Nanny-state accusations are largely accusations of paternalism. They conjure up emotive concern about undue governmental interference undermining peoples' autonomy. But autonomy can be understood in various ways. We outline three main conceptions of autonomy, argue that these that can underpin three different conceptions of paternalism, and consider implications for responses to nanny-state accusations and the assessment of public health interventions. Detailed conceptual analysis. The conceptions of paternalism implicit in nanny-state accusations generally depend on libertarian conceptions of autonomy. These reflect unrealistic views of personal independence and do not discriminate sufficiently between trivial and important freedoms. Decisional conceptions of paternalism, like their underlying decisional conceptions of autonomy, have limited applicability in public health contexts. Relational conceptions of paternalism incorporate relational conceptions of autonomy, so recognize that personal autonomy depends on socially shaped skills, self-identities and self-evaluations as well as externally structured opportunities. They encourage attention to the various ways that social interactions and relationships, including disrespect, stigmatization and oppression, can undermine potential for autonomy. While nanny-state accusations target any interference with negative freedom, however trivial, relational conceptions direct concerns to those infringements of negative freedom, or absences of positive freedom, serious enough to undermine self-determination, self-governance and/or self-authorization. Relational conceptions of autonomy and paternalism offer public health policymakers and practitioners a means for rebutting nanny-state accusations, and can support more nuanced

Topological domain walls in helimagnets

Science.gov (United States)

Schoenherr, P.; Müller, J.; Köhler, L.; Rosch, A.; Kanazawa, N.; Tokura, Y.; Garst, M.; Meier, D.

2018-05-01

Domain walls naturally arise whenever a symmetry is spontaneously broken. They interconnect regions with different realizations of the broken symmetry, promoting structure formation from cosmological length scales to the atomic level1,2. In ferroelectric and ferromagnetic materials, domain walls with unique functionalities emerge, holding great promise for nanoelectronics and spintronics applications3-5. These walls are usually of Ising, Bloch or Néel type and separate homogeneously ordered domains. Here we demonstrate that a wide variety of new domain walls occurs in the presence of spatially modulated domain states. Using magnetic force microscopy and micromagnetic simulations, we show three fundamental classes of domain walls to arise in the near-room-temperature helimagnet iron germanium. In contrast to conventional ferroics, the domain walls exhibit a well-defined inner structure, which—analogous to cholesteric liquid crystals—consists of topological disclination and dislocation defects. Similar to the magnetic skyrmions that form in the same material6,7, the domain walls can carry a finite topological charge, permitting an efficient coupling to spin currents and contributions to a topological Hall effect. Our study establishes a new family of magnetic nano-objects with non-trivial topology, opening the door to innovative device concepts based on helimagnetic domain walls.

Public acceptance of nuclear power generation in the United States

International Nuclear Information System (INIS)

Liverman, J.L.; Thorne, R.D.

1977-01-01

Within the United States environmental awareness has spread and matured since the early 1960's. Evidence of this is found in cautious attitudes toward the installation of nuclear power reactors and other components of the nuclear fuel cycle. Hazards associated with nuclear energy technologies appear to attract a greater share of public attention than the hazards of nonnuclear counterparts. The association of nuclear power with nuclear weapons may be at the root of this concern. The explicit identification of increased incidences of cancer and genetic effects in humans as potential consequences of exposure to ionizing radiation and knowledge that radiation exposures and health consequences arising from nuclear power operations might occur many generations after operations cease also underlie this concern. Based in large part on these concerns, a number of actions have been taken in the United States to prevent and to delay installation and development of nuclear technology. These actions are reviewed and analyzed with emphasis on the 1976 California nuclear moratorium referendum and other more recent actions at state and national levels. They are compared with the status and outcome of similar actions in other nations as is possible. Additionally, ERDA's current approaches to public involvement in the decision making process is discussed, including the value of comprehensive analyses of health, environmental, and socioeconomic aspects of alternative energy sources in responding to public needs. U.S. plans for providing such analyses for all installed and developing energy technologies are presented with special reference to areas which require international cooperation for implementation. The value of international analysis and internationally accepted environmental control strategies for all energy technologies is also addressed

Public Governance and Governability: Accountability and Disclosure permitted by Accounting Applied to the Public Sector as a Sustainability Instrument for the State

Directory of Open Access Journals (Sweden)

Antonio Gonçalves Oliveira

2013-03-01

Full Text Available In an accounting-financial perspective applied to business organizations, the Going-Concern Principle presupposes their sustainability towards perpetuity, influencing and guaranteeing investors’ returns. In Public Management, this is no different, underlining the existence of the Going-Concern Principle of the State. This describes the State as a political society that, like the company, should be perennial and sustainable, always aiming for the promotion of the common good and the development of its people. In line with the expected contribution, this paper is aimed at discussing the importance of Accounting Applied to the Public Sector as a useful tool for effective Public Governance and Governability, in accordance with a sustainability view that is applicable to the management of the State. What the method is concerned, regarding the ends, it was an exploratory and explanatory research and, regarding the means, bibliographic and documentary research and theoreticalempirical observation were used, focusing on compliance with Public Management disclosure (transparency and accountability (social responsibility to render accounts to society. As a result, a strong interrelation between the terms was verified, as Accounting evidences governments’ results and actions based on governance (the means/the how related to governability (political power and actions, and also that both are oriented towards the sustainability of the State. As regards the latter, it was also verified that it is more comprehensive than the term “sustainability” itself, which is often narrowed down to the eco-environmental view and ignores important financial (equilibrium and economic-social variables inherent in the social function of the State Como.

1H-detected MAS solid-state NMR experiments enable the simultaneous mapping of rigid and dynamic domains of membrane proteins

Science.gov (United States)

Gopinath, T.; Nelson, Sarah E. D.; Veglia, Gianluigi

2017-12-01

Magic angle spinning (MAS) solid-state NMR (ssNMR) spectroscopy is emerging as a unique method for the atomic resolution structure determination of native membrane proteins in lipid bilayers. Although 13C-detected ssNMR experiments continue to play a major role, recent technological developments have made it possible to carry out 1H-detected experiments, boosting both sensitivity and resolution. Here, we describe a new set of 1H-detected hybrid pulse sequences that combine through-bond and through-space correlation elements into single experiments, enabling the simultaneous detection of rigid and dynamic domains of membrane proteins. As proof-of-principle, we applied these new pulse sequences to the membrane protein phospholamban (PLN) reconstituted in lipid bilayers under moderate MAS conditions. The cross-polarization (CP) based elements enabled the detection of the relatively immobile residues of PLN in the transmembrane domain using through-space correlations; whereas the most dynamic region, which is in equilibrium between folded and unfolded states, was mapped by through-bond INEPT-based elements. These new 1H-detected experiments will enable one to detect not only the most populated (ground) states of biomacromolecules, but also sparsely populated high-energy (excited) states for a complete characterization of protein free energy landscapes.

The new PR of states: How nation branding practices affect the security function of public diplomacy

DEFF Research Database (Denmark)

Rasmussen, Rasmus Kjærgaard; Merkelsen, Henrik

2012-01-01

This paper investigates how the role of public relations practice in public diplomacy is undergoing a transformation as a consequence of the influence from nation branding. A case study of the Danish government's response to the so-called Cartoon Crisis illustrates how the threat from international...... a domestic audience. In the public diplomacy efforts towards transnational publics the link to national security will completely disappear whereby the public relations of states is transformed to the marketing of states....... terrorism to national security initially served as a catalyst for new public diplomacy initiatives. But as the initiatives were implemented within a framework of nation branding the focus on risk reduction became subjected to a marketing logic and a new focus on economic objectives took over. The paper...

Public Education Finance Systems in the United States and Funding Policies for Populations with Special Educational Needs

Science.gov (United States)

Verstegen, Deborah A.

2011-01-01

This research investigates state finance policies for public education using survey methodology. The purpose is to update previous work and the existing knowledge base in the field as well as to provide a compendium of finance and policy options that are used across the states to finance public elementary and secondary schools. Chief state school…

Opening of energy markets: consequences on the missions of public utility and of security of supplies in the domain of electric power and gas

International Nuclear Information System (INIS)

2001-01-01

This conference was jointly organized by the International Energy Agency (IEA) and the French ministry of economy, finances, and industry (general direction of energy and raw materials, DGEMP). It was organized in 6 sessions dealing with: 1 - the public utility in the domain of energy: definition of the public utility missions, experience feedback about liberalized markets, public utility obligation and pricing regulation; 2 - the new US energy policy and the lessons learnt from the California crisis; 3 - the security of electric power supplies: concepts of security of supplies, opinion of operators, security of power supplies versus liberalization and investments; 4 - security of gas supplies: markets liberalization and investments, long-term contracts and security of supplies; 5 - debate: how to integrate the objectives of public utility and of security of supplies in a competing market; 6 - conclusions. This document brings together the available talks and transparencies presented at the conference. (J.S.)

Matter antimatter domains: A possible solution to the CP domain wall problem in the early universe

Science.gov (United States)

Mohanty, A. K.; Stecker, F. W.

1984-01-01

An SU(5) grand unified theory model is used to show how the degeneracy between vacua with different spontaneously broken charge parity can be dynamically lifted by a condensate of heavy fermion pairs. This drives a phase transition to a unique vacuum state with definite charge parity. The transition eliminates the domain walls in a matter antimatter symmetric domain cosmology.

Carbon Stocks and Projections on Public Forestlands in the United States, 1952-2040

Science.gov (United States)

James E. Smith; Linda S. Heath

2004-01-01

Approximately 37% of forestlands in the conterminous United States are publicly owned; they represent a substantial area of potential carbon sequestration in US forests and in forest products. However, large areas of public forestlands traditionally have been less intensively inventoried than privately owned forests. Thus, less information is available about their role...

Clustering of physical inactivity in leisure, work, commuting and household domains among Brazilian adults.

Science.gov (United States)

Del Duca, G F; Nahas, M V; de Sousa, T F; Mota, J; Hallal, P C; Peres, K G

2013-06-01

To identify the clustering of physical inactivity in leisure, work, commuting and household contexts, and the sociodemographic factors associated with the clustering of inactive behaviour in different domains among Brazilian adults. Cross-sectional population-based study. The study was performed in Florianopolis, capital of Santa Catarina, one of the southern states of Brazil, from September 2009 to January 2010. Adults aged 20-59 years were interviewed. Physical inactivity in each domain was defined as non-participation in specific physical activities, using a validated Brazilian questionnaire. Clustering of physical inactivity was identified by the ratio between observed prevalence and expected prevalence of 16 different combinations. Multinomial logistic regression was used in the analysis of sociodemographic factors associated with clustering of physical inactivity. Of the 1720 interviewees, the greatest differences between the observed and expected proportions were observed in simultaneous physical inactivity in the leisure and household domains for men, and physical inactivity in the leisure domain alone for women (59% and 88%, respectively); these differences were higher than expected if the behaviours were independent. Physical inactivity in two or more domains was observed more frequently in men and in individuals with a higher per-capita family income. Ageing was associated with physical inactivity in three or four domains. Physical inactivity was observed in different domains according to gender. Men and older individuals with a higher per-capita family income were more likely to exhibit physical inactivity when all domains were considered together. Copyright © 2013 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Ferroelectric negative capacitance domain dynamics

Science.gov (United States)

Hoffmann, Michael; Khan, Asif Islam; Serrao, Claudy; Lu, Zhongyuan; Salahuddin, Sayeef; Pešić, Milan; Slesazeck, Stefan; Schroeder, Uwe; Mikolajick, Thomas

2018-05-01

Transient negative capacitance effects in epitaxial ferroelectric Pb(Zr0.2Ti0.8)O3 capacitors are investigated with a focus on the dynamical switching behavior governed by domain nucleation and growth. Voltage pulses are applied to a series connection of the ferroelectric capacitor and a resistor to directly measure the ferroelectric negative capacitance during switching. A time-dependent Ginzburg-Landau approach is used to investigate the underlying domain dynamics. The transient negative capacitance is shown to originate from reverse domain nucleation and unrestricted domain growth. However, with the onset of domain coalescence, the capacitance becomes positive again. The persistence of the negative capacitance state is therefore limited by the speed of domain wall motion. By changing the applied electric field, capacitor area or external resistance, this domain wall velocity can be varied predictably over several orders of magnitude. Additionally, detailed insights into the intrinsic material properties of the ferroelectric are obtainable through these measurements. A new method for reliable extraction of the average negative capacitance of the ferroelectric is presented. Furthermore, a simple analytical model is developed, which accurately describes the negative capacitance transient time as a function of the material properties and the experimental boundary conditions.

Public Sector Employment Inequality in the United States and the Great Recession.

Science.gov (United States)

Laird, Jennifer

2017-02-01

Historically in the United States, the public sector has served as an equalizing institution through the expansion of job opportunities for minority workers. This study examines whether the public sector continues to serve as an equalizing institution in the aftermath of the Great Recession. Using data from the Current Population Survey, I investigate changes in public sector employment between 2003 and 2013. My results point to a post-recession double disadvantage for black public sector workers: they are concentrated in a shrinking sector of the economy, and they are more likely than white and Hispanic public sector workers to experience job loss. These two trends are a historical break for the public sector labor market. I find that race and ethnicity gaps in public sector employment cannot be explained by differences in education, occupation, or any of the other measurable factors that are typically associated with employment. Among unemployed workers who most recently worked for the public sector, black women are the least likely to transition into private sector employment.

Social Media Analysis For Organizations: Us Northeastern Public And State Libraries Case Study

OpenAIRE

Collins, Matthew; Karami, Amir

2018-01-01

Social networking sites such as Twitter have provided a great opportunity for organizations such as public libraries to disseminate information for public relations purposes. However, there is a need to analyze vast amounts of social media data. This study presents a computational approach to explore the content of tweets posted by nine public libraries in the northeastern United States of America. In December 2017, this study extracted more than 19,000 tweets from the Twitter accounts of sev...

Organizational models of public administration: a study of some aspects of the reality derived from Ceara State reform

Directory of Open Access Journals (Sweden)

Maria Lucineide Serpa Gomes

2010-01-01

Full Text Available The new public management is a much-debated issue in Brazil and in many other countries worldwide. Its origin is historically dated in the 80´s, attributed to State economic and fiscal crises that had reached many countries in that decade and was also a response to State Welfare deterioration. The answer given prescribed a set of policies that proclaimed the application of market principles and private sector logic to the Public Administration. The study has as the objective to analyze the relation between the new public model practices and the modernization and efficiency of the State administration. The specific objectives are concentrated on presenting the models of Public Administration; on identifying reforms carried through in Brazilian Public Administration until the current days; on analyzing managerial practices of the new model applied to state administration. This is an exploratory, qualitative and documentary research. Interviews had been carried out, and then, the study made use of the technique of content analysis. To choose the respondents in the field research, the study considered the criterion of linking the interviewee to the process of modernization of the Public Administration. Thus, managers, former-managers of the main state secretariats involved with modernization of public administration, and researchers who had previously taken part in this process were selected. The contribution of this work results in a better evaluation of the modernization of the state Administration and also of its consequences.

Certification of Public Librarians in the United States; A Detailed Summary of Legal and Voluntary Certification Plans for Public Librarians Based on Information Supplied by the Various Certificating State Agencies or other Appropriate Sources, 2nd Edition.

Science.gov (United States)

Frame, Ruth R.; Coyne, John R.

Contained in this report is a detailed summary of legal and voluntary certification plans for public librarians in each of the 50 states. Descriptions of the certification plans for public librarians are based on information supplied by state agencies in September 1971. Each plan is identified by the descriptive terms--mandatory, permissive or…

Places of the Heart: Memorials, Public History and the State in Australia Since 1960

Directory of Open Access Journals (Sweden)

Paul Ashton

2008-08-01

Full Text Available Memorials as a form of public history allow us to chart the complex interactions and negotiations between officially endorsed historical narratives, public memorials, privately sponsored memorials in public spaces and new histories. As Ludmilla Jordanova reminds us, ‘the state… lies at the heart of public history’. And this is evident in the public process of memorialisation. At one level, the state endorses certain narratives within which communities and organisations need to operate if they are to be officially part of the national story and its regional and local variants. Ultimate endorsement for memorials includes listings on heritage registers. Controls over the erection of memorials vary from official policies to process for the issue of permits for their construction in public places or their removal. The state, however, is not monolithic. Permissible pasts evolve over time given shifts in power and social and cultural change. This involves both ‘retrospective commemoration’ and ‘participatory memorialisation’. The presence and power of the past in peoples’ lives, too, means in practice that memorial landscapes will reflect, in truly democratic societies, the values, experiences and dominant concerns of its citizens.

Prediction Reweighting for Domain Adaptation.

Science.gov (United States)

Shuang Li; Shiji Song; Gao Huang

2017-07-01

There are plenty of classification methods that perform well when training and testing data are drawn from the same distribution. However, in real applications, this condition may be violated, which causes degradation of classification accuracy. Domain adaptation is an effective approach to address this problem. In this paper, we propose a general domain adaptation framework from the perspective of prediction reweighting, from which a novel approach is derived. Different from the major domain adaptation methods, our idea is to reweight predictions of the training classifier on testing data according to their signed distance to the domain separator, which is a classifier that distinguishes training data (from source domain) and testing data (from target domain). We then propagate the labels of target instances with larger weights to ones with smaller weights by introducing a manifold regularization method. It can be proved that our reweighting scheme effectively brings the source and target domains closer to each other in an appropriate sense, such that classification in target domain becomes easier. The proposed method can be implemented efficiently by a simple two-stage algorithm, and the target classifier has a closed-form solution. The effectiveness of our approach is verified by the experiments on artificial datasets and two standard benchmarks, a visual object recognition task and a cross-domain sentiment analysis of text. Experimental results demonstrate that our method is competitive with the state-of-the-art domain adaptation algorithms.

Transcript structure and domain display: a customizable transcript visualization tool.

Science.gov (United States)

Watanabe, Kenneth A; Ma, Kaiwang; Homayouni, Arielle; Rushton, Paul J; Shen, Qingxi J

2016-07-01

Transcript Structure and Domain Display (TSDD) is a publicly available, web-based program that provides publication quality images of transcript structures and domains. TSDD is capable of producing transcript structures from GFF/GFF3 and BED files. Alternatively, the GFF files of several model organisms have been pre-loaded so that users only needs to enter the locus IDs of the transcripts to be displayed. Visualization of transcripts provides many benefits to researchers, ranging from evolutionary analysis of DNA-binding domains to predictive function modeling. TSDD is freely available for non-commercial users at http://shenlab.sols.unlv.edu/shenlab/software/TSD/transcript_display.html : jeffery.shen@unlv.nevada.edu. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Turning point: the Robert Wood Johnson Foundation's effort to revitalize public health at the state level.

Science.gov (United States)

Hassmiller, Susan

2002-01-01

The Robert Wood Johnson (RWJ) Foundation initiated Turning Point in collaboration with the W.K. Kellogg Foundation (Kellogg) in 1997. The purpose of this major national initiative was to strengthen the public health infrastructure in the United States so that states, local communities, and their public health agencies might respond to the challenge to protect and improve the public's health in the 21st century. RWJ funded 21 states and Kellogg funded 43 communities to work together to create a new way of thinking about how health could be improved and who should be involved. Although the ultimate outcome was to improve health, both foundations expected diverse partnerships to work together to create strategic health improvement plans at both the community and state levels. The foundations funded a variety of strategies within those health improvement plans during an implementation phase. The premise in funding partnerships, as opposed to a single entity, was that effective public health systems would be developed best through a shared responsibility (including the private sector) for the health of a community.

Human exposure to rabid free-ranging cats: a continuing public health concern in Pennsylvania.

Science.gov (United States)

Campagnolo, E R; Lind, L R; Long, J M; Moll, M E; Rankin, J T; Martin, K F; Deasy, M P; Dato, V M; Ostroff, S M

2014-08-01

Rabid free-ranging cats have been a public health concern in Pennsylvania since raccoon variant rabies first was recognized in the state in the early 1980s. Over the last decade, between 1.5 and 2.5% of cats submitted to Pennsylvania's state laboratories for rabies testing have been positive. In this report, we describe the extent of rabies in free-ranging cats in Pennsylvania. We also present two examples of human exposure to rabid free-ranging cats that occurred in Pennsylvania during 2010-2011 and the public health actions taken to address rabies exposure in the humans and animals. We then describe the concerns surrounding the unvaccinated and free-ranging cat population in Pennsylvania and possible options in managing this public and animal health problem. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

The Measurement and Role of Ecological Resilience Systems Theory Across Domain-Specific Outcomes: The Domain-Specific Resilient Systems Scales.

Science.gov (United States)

Maltby, John; Day, Liz; Hall, Sophie S; Chivers, Sally

2017-10-01

Research suggests that trait resilience may be best understood within an ecological resilient systems theory, comprising engineering, ecological, and adaptive capacity resilience. However, there is no evidence as to how this theory translates to specific life domains. Data from two samples (the United States, n = 1,278; the United Kingdom, n = 211) facilitated five studies that introduce the Domain-Specific Resilient Systems Scales for assessing ecological resilient systems theory within work, health, marriage, friendships, and education. The Domain-Specific Resilient Systems Scales are found to predict unique variance in job satisfaction, lower job burnout, quality-of-life following illness, marriage commitment, and educational engagement, while controlling for factors including sex, age, personality, cognitive ability, and trait resilience. The findings also suggest a distinction between the three resilience dimensions in terms of the types of systems to which they contribute. Engineering resilience may contribute most to life domains where an established system needs to be maintained, for example, one's health. Ecological resilience may contribute most to life domains where the system needs sustainability in terms of present and future goal orientation, for example, one's work. Adaptive Capacity may contribute most to life domains where the system needs to be retained, preventing it from reaching a crisis state, for example, work burnout.

Availability of medicines in public sector health facilities of two North Indian States.

Science.gov (United States)

Prinja, Shankar; Bahuguna, Pankaj; Tripathy, Jaya Prasad; Kumar, Rajesh

2015-12-23

Access to free essential medicines is a critical component of universal health coverage. However availability of essential medicines is poor in India with more than two-third of the people having limited or no access. This has pushed up private out-of-pocket expenditure due to medicines. The states of Punjab and Haryana are in the process of institutionalizing drug procurement models to provide uninterrupted access to essential medicines free of cost in all public hospitals and health centres. We undertook this study to assess the availability of medicines in public sector health facilities in the 2 states. Secondly, we also ascertained the quality of storage and inventory management systems in health facilities. The present study was carried out in 80 public health facilities across 12 districts in Haryana and Punjab states. Overall, within each state 1 MC, 6 DHs, 11 CHCs and 22 PHCs were selected for the study. Drug procurement mechanisms in both the states were studied through document reviews and in-depth interviews with key stakeholders. Stock registers were reviewed to collect data on availability of a basket of essential medicines -92 at Primary Health Centre (PHC) level, 132 at Community Health Centre (CHC) level and 160 at tertiary care (District Hospital/Medical College) level. These essential medicines were selected based on the Essential Medicine List (EML) of the Department of Health (DOH). Overall availability of medicines was 45.2% and 51.1% in Punjab and Haryana respectively. Availability of anti-hypertensives was around 60% in both the states whereas for anti-diabetics it was 44% and 47% in Punjab and Haryana respectively. Atleast one drug in each of the categories including analgesic/antipyretic, anti-helminthic, anti-spasmodic, anti-emetic, anti-hypertensive and uterotonics were nearly universally available in public sector facilities. On the contrary, medicines such as thrombolytics, anti-cancer and endocrine medicines were available in less

An Approach to Coordinate Efforts to Reduce the Public Health Burden of Stroke: The Delta States Stroke Consortium

OpenAIRE

Virginia J. Howard; Joe Acker; Camilo R. Gomez; Ada H. Griffies; Wanda Magers; Max Michael III; Sean R. Orr; Martha Phillips; James M. Raczynski; John E. Searcy; Richard M. Zweifler; George Howard

2004-01-01

Stroke is the third leading cause of death and a leading cause of disability in the United States, with a particularly high burden on the residents of the southeastern states, a region dubbed the Stroke Belt. These five states Alabama, Arkansas, Louisiana, Mississippi, and Tennessee have formed the Delta States Stroke Consortium to direct efforts to reduce this burden. The consortium is proposing an approach to identify domains where interventions may be instituted and an array of activitie...

State Tuition, Fees, and Financial Assistance Policies: For Public Colleges and Universities, 2010-11

Science.gov (United States)

Bell, Allison C.; Carnahan, Julie; L'Orange, Hans P.

2011-01-01

This report, "State Tuition, Fees, and Financial Assistance Policies for Public Colleges and Universities: 2010-11", examines the philosophies, policies, and procedures that influence decision-making regarding public college and university tuition, student fees, and student financial aid programs. This report also provides information…

77 FR 33456 - Public Water Supply Supervision Program; Program Revision for the State of Washington

Science.gov (United States)

2012-06-06

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9682-4] Public Water Supply Supervision Program; Program... State Public Water Supply Supervision Primacy Program. Washington has adopted regulations analogous to... of Health--Office of Drinking Water, [[Page 33457

Nongovernment Philanthropic Spending on Public Health in the United States.

Science.gov (United States)

Shaw-Taylor, Yoku

2016-01-01

The objective of this study was to estimate the dollar amount of nongovernment philanthropic spending on public health activities in the United States. Health expenditure data were derived from the US National Health Expenditures Accounts and the US Census Bureau. Results reveal that spending on public health is not disaggregated from health spending in general. The level of philanthropic spending is estimated as, on average, 7% of overall health spending, or about $150 billion annually according to National Health Expenditures Accounts data tables. When a point estimate of charity care provided by hospitals and office-based physicians is added, the value of nongovernment philanthropic expenditures reaches approximately $203 billion, or about 10% of all health spending annually.

Examining the Effect of Exposure Therapy on Public Speaking State Anxiety

Science.gov (United States)

Finn, Amber N.; Sawyer, Chris R.; Schrodt, Paul

2009-01-01

Increased public speaking confidence is often cited as a major benefit for undergraduates taking the basic communication course. Several scholars have reported that the state anxiety of novice speakers declines progressively during performance, a phenomenon called within-session habituation. However, the contributions of these short-term…

Costs at Public Universities: How Does California Compare with Other States? Report 10-12

Science.gov (United States)

Fuller, Ryan

2010-01-01

The cost of attending the University of California (UC) and California State University (CSU) has increased in recent years as UC and CSU have raised fees in response to reduced state funding. Fees are generally lower than fees at public universities in other states, but with California's higher living costs, the overall cost of attendance at UC…

United States private schools have higher rates of exemptions to school immunization requirements than public schools.

Science.gov (United States)

Shaw, Jana; Tserenpuntsag, Boldtsetseg; McNutt, Louise-Anne; Halsey, Neal

2014-07-01

To compare medical, religious, and personal belief immunization exemption rates between private and public schools in US. Exemption rates were calculated using the Centers for Disease Control and Prevention School Immunization Assessment Surveys for the 2009-2010 school year excluding states with incomplete survey data. Standardized exemption rates weighted on enrollments in public and private schools were calculated. Differences in exemption rates between public and private schools were tested using Wilcoxon signed rank test. The overall state exemption rate was higher in US private than public schools, 4.25% (SD 4.27) vs 1.91% (1.67), P = .0001 and private schools had higher exemption rates for all types of exemptions; medical 0.58% (0.71) vs 0.34% (0.34) respectively (P = .0004), religious 2.09% (3.14) vs 0.83% (1.05) respectively (P = .0001), and personal belief 6.10% (4.12) vs 2.79% (1.57), respectively (P = .006). Overall exemption rates were significantly higher in states that allowed personal belief exemptions. Exemption rates were significantly higher in US private than in public schools. Children attending private schools may be at higher risk of vaccine-preventable diseases than public school children. Copyright © 2014 Elsevier Inc. All rights reserved.

Towards a minimal generic set of domains of functioning and health.

Science.gov (United States)

Cieza, Alarcos; Oberhauser, Cornelia; Bickenbach, Jerome; Chatterji, Somnath; Stucki, Gerold

2014-03-03

The World Health Organization (WHO) has argued that functioning, and, more concretely, functioning domains constitute the operationalization that best captures our intuitive notion of health. Functioning is, therefore, a major public-health goal. A great deal of data about functioning is already available. Nonetheless, it is not possible to compare and optimally utilize this information. One potential approach to address this challenge is to propose a generic and minimal set of functioning domains that captures the experience of individuals and populations with respect to functioning and health. The objective of this investigation was to identify a minimal generic set of ICF domains suitable for describing functioning in adults at both the individual and population levels. We performed a psychometric study using data from: 1) the German National Health Interview and Examination Survey 1998, 2) the United States National Health and Nutrition Examination Survey 2007/2008, and 3) the ICF Core Set studies. Random Forests and Group Lasso regression were applied using one self-reported general-health question as a dependent variable. The domains selected were compared to those of the World Health Survey (WHS) developed by the WHO. Seven domains of the International Classification of Functioning, Disability and Health (ICF) are proposed as a minimal generic set of functioning and health: energy and drive functions, emotional functions, sensation of pain, carrying out daily routine, walking, moving around, and remunerative employment. The WHS domains of self-care, cognition, interpersonal activities, and vision were not included in our selection. The minimal generic set proposed in this study is the starting point to address one of the most important challenges in health measurement--the comparability of data across studies and countries. It also represents the first step in developing a common metric of health to link information from the general population to information

Psychometric characteristics of a public-domain self-report measure of vocational interests: the Oregon Vocational Interest Scales.

Science.gov (United States)

Pozzebon, Julie A; Visser, Beth A; Ashton, Michael C; Lee, Kibeom; Goldberg, Lewis R

2010-03-01

We investigated the psychometric properties of the Oregon Vocational Interest Scales (ORVIS), a brief public-domain alternative to commercial inventories, in a large community sample and in a college sample. In both samples, we examined the factor structure, scale intercorrelations, and personality correlates of the ORVIS, and in the community sample, we also examined the correlations of the ORVIS scales with cognitive abilities and with the scales of a longer, proprietary interest survey. In both samples, all 8 scales-Leadership, Organization, Altruism, Creativity, Analysis, Producing, Adventuring, and Erudition-showed wide variation in scores, high internal-consistency reliabilities, and a pattern of high convergent and low discriminant correlations with the scales of the proprietary interest survey. Overall, the results support the construct validity of the scales, which are recommended for use in research on vocational interests and other individual differences.

La apropiación del dominio público y las posibilidades de acceso a los bienes culturales | The appropriation of the public domain and the possibilities of access to cultural goods

Directory of Open Access Journals (Sweden)

Joan Ramos Toledano

2017-06-01

Full Text Available Resumen: Las normas de propiedad intelectual y copyright prevén un periodo de protección otorgando unos derechos económicos exclusivos y temporales. Pasado un plazo determinado, las obras protegidas entran en lo que se denomina dominio público. Éste suele ser considerado como el momento en el que los bienes culturales pasan a estar bajo el dominio y control de la sociedad en conjunto. El presente trabajo pretende argumentar que, dado nuestro actual sistema económico, en realidad el dominio público funciona más como una posibilidad de negocio para determinadas empresas que como una verdadera opción para que el público pueda acceder a las obras.   Abstract: The legislation of continental intellectual property and copyright provide for a period of protection granting exclusive and temporary economic rights. After a certain period, protected works enter into what is called the public domain. This is often considered as the moment in which the cultural goods come under the control and domain of society as a whole. The present paper pretends to argue that, given our current economic system, the public domain actually functions more as a business opportunity for certain companies than as a real option for the public to access artistic and intellectual works.

The Efficiency and Public Transport Accessibility of Indirect State Administration in the Czech Republic

Directory of Open Access Journals (Sweden)

Vrabková Iveta

2016-06-01

Full Text Available This paper examines the efficiency and public transport accessibility of indirect (devolved state administration performed by municipalities with extended powers (hereinafter MEPs in the Czech Republic. Our aim is to evaluate the efficiency of the revenues made by municipalities with extended powers, through performing powers delegated to them by the state administration, and those municipalities’ public transport accessibility as of 31 December, 2014. The rate of efficiency is tested on an output-oriented Free Disposable Hull model. One input variable is selected - the operating expenses of the municipal offices recalculated per inhabitant of the municipality’s administrative district - and two output variables are selected: contribution to the performance of state administration, recalculated per inhabitant of the municipality’s administrative district, and revenues from administrative fees per inhabitant of the municipality’s administrative district. The municipality’s offices’ transport accessibility is evaluated via network analysis using ArcGIS software. The article investigates the hypothesis that public administration deconcentration practices logically result in higher security costs and therefore inefficiency. The results reveal that only 66 of the country’s 205 MEPs are efficient and that operating expenses and state contributions for the performance of state administrative tasks play a significant role in these results. Efficiency is less significantly influenced by administrative fee revenues. Public transport accessibility is analyzed for two time intervals - 6:00 to 8:00 am and 1:00 to 2:00 pm - on Tuesdays. The degree of accessibility is defined using a six-point scale of accessibility. The results show that the best accessibility is in the morning hours, when the offices are accessible for 68.8% of the population aged 15+ in the Czech Republic; the worst accessibility is in the afternoon hours when only 2% of the

Selected ICAR Data from the SAPA-Project: Development and Initial Validation of a Public-Domain Measure

Directory of Open Access Journals (Sweden)

David M. Condon

2016-01-01

Full Text Available These data were collected during the initial evaluation of the International Cognitive Ability Resource (ICAR project. ICAR is an international collaborative effort to develop open-source public-domain tools for cognitive ability assessment, including tools that can be administered in non-proctored environments (e.g., online administration and those which are based on automatic item generation algorithms. These data provide initial validation of the first four ICAR item types as reported in Condon & Revelle [1]. The 4 item types contain a total of 60 items: 9 Letter and Number Series items, 11 Matrix Reasoning items, 16 Verbal Reasoning items and 24 Three-dimensional Rotation items. Approximately 97,000 individuals were administered random subsets of these 60 items using the Synthetic Aperture Personality Assessment method between August 18, 2010 and May 20, 2013. The data are available in rdata and csv formats and are accompanied by documentation stored as a text file. Re-use potential includes a wide range of structural and item-level analyses.

SH2 domains: modulators of nonreceptor tyrosine kinase activity

OpenAIRE

Filippakopoulos, Panagis; Müller, Susanne; Knapp, Stefan

2009-01-01

The Src homology 2 (SH2) domain is a sequence-specific phosphotyrosine-binding module present in many signaling molecules. In cytoplasmic tyrosine kinases, the SH2 domain is located N-terminally to the catalytic kinase domain (SH1) where it mediates cellular localization, substrate recruitment, and regulation of kinase activity. Initially, structural studies established a role of the SH2 domain stabilizing the inactive state of Src family members. However, biochemical characterization showed ...

Ubiquitin domain proteins in disease

DEFF Research Database (Denmark)

Klausen, Louise Kjær; Schulze, Andrea; Seeger, Michael

2007-01-01

The human genome encodes several ubiquitin-like (UBL) domain proteins (UDPs). Members of this protein family are involved in a variety of cellular functions and many are connected to the ubiquitin proteasome system, an essential pathway for protein degradation in eukaryotic cells. Despite...... and cancer. Publication history: Republished from Current BioData's Targeted Proteins database (TPdb; http://www.targetedproteinsdb.com)....

Norwegian public health policy: revitalization of the social democratic welfare state?

Science.gov (United States)

Fosse, Elisabeth

2009-01-01

Norway is part of the so-called social democratic welfare state model, which is characterized by its emphasis on solidarity and redistribution among social groups. The concepts of upstream and downstream policy measures may be useful to characterize different approaches to public health policies: upstream measures would be structural measures, in line with the social democratic welfare state model, while downstream measures would be more targeted at individuals or groups at some sort of risk. The aim of this article is to analyze national policies in Norway and how these may be characterized in terms of upstream and downstream factors. Health promotion and public health policies have been high on the Norwegian political agenda for two decades. However, the national policy emphasis has shifted between strategies aimed at individuals and structural strategies--that is, between downstream and upstream measures. Until 2003, policies included mainly downstream measures, but since then a policy shift has taken place and current policy includes an emphasis on upstream measures. This policy was strengthened after a left-wing coalition came into government in 2005. It may be argued that the present policy represents a revitalization of universal and structural measures, in line with the social democratic welfare state model.

In search of a consensus model of the resting state of a voltage-sensing domain.

Science.gov (United States)

Vargas, Ernesto; Bezanilla, Francisco; Roux, Benoît

2011-12-08

Voltage-sensing domains (VSDs) undergo conformational changes in response to the membrane potential and are the critical structural modules responsible for the activation of voltage-gated channels. Structural information about the key conformational states underlying voltage activation is currently incomplete. Through the use of experimentally determined residue-residue interactions as structural constraints, we determine and refine a model of the Kv channel VSD in the resting conformation. The resulting structural model is in broad agreement with results that originate from various labs using different techniques, indicating the emergence of a consensus for the structural basis of voltage sensing. Copyright © 2011 Elsevier Inc. All rights reserved.

Poster project to emphasize public health in the pharmacy curriculum.

Science.gov (United States)

Kelsch, Michael P; Werremeyer, Amy B

2011-02-10

To implement and assess a required public health poster project in a doctor of pharmacy (PharmD) program. Third-year PharmD students collaborated in pairs to research a public health topic relating to pharmacy practice. Each student group prepared an informational poster, while receiving feedback from a faculty mentor at each stage of the project. The students presented their completed posters at a statewide pharmacy conference. Faculty members evaluated the posters with a grading rubric, and students completed a survey instrument that assessed the overall experience. In general, faculty members rated the class highly across all domains of the grading rubric. The class generally agreed that the poster project increased their awareness of public health issues related to pharmacy practice, overall knowledge of public health, and presentation skills. The implementation of a poster project was well received by students and faculty members as an effective method for enhancing public health instruction in the PharmD program at North Dakota State University.

Fraud Prevention and Employee Rationalization in New York State Public Schools

Science.gov (United States)

Slezak, Kathleen

2013-01-01

Prompted by frequent media reports of school fraud and a lack of relevant K-12 literature, this research study was designed to investigate current fraud prevention practices in public school districts in New York State. Using a "fraud triangle" model, an analysis of existing legislation and professional practice guidelines reveals that…

Single-domain epitaxial silicene on diboride thin films

Energy Technology Data Exchange (ETDEWEB)

Fleurence, A., E-mail: antoine@jaist.ac.jp; Friedlein, R.; Aoyagi, K.; Yamada-Takamura, Y. [School of Materials Science, Japan Advanced Institute of Science and Technology (JAIST), 1-1 Asahidai, Nomi, Ishikawa 923-1292 (Japan); Gill, T. G. [School of Materials Science, Japan Advanced Institute of Science and Technology (JAIST), 1-1 Asahidai, Nomi, Ishikawa 923-1292 (Japan); London Centre for Nanotechnology, University College London (UCL), London WC1H 0AH (United Kingdom); Department of Chemistry, UCL, London WC1H 0AJ (United Kingdom); Sadowski, J. T. [Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, New York 11973 (United States); Copel, M.; Tromp, R. M. [IBM Research Division, Thomas J. Watson Research Center, Yorktown Heights, New York 10598 (United States); Hirjibehedin, C. F. [London Centre for Nanotechnology, University College London (UCL), London WC1H 0AH (United Kingdom); Department of Chemistry, UCL, London WC1H 0AJ (United Kingdom); Department of Physics and Astronomy, UCL, London WC1E 6BT (United Kingdom)

2016-04-11

Epitaxial silicene, which forms spontaneously on ZrB{sub 2}(0001) thin films grown on Si(111) wafers, has a periodic stripe domain structure. By adsorbing additional Si atoms on this surface, we find that the domain boundaries vanish, and a single-domain silicene sheet can be prepared without altering its buckled honeycomb structure. The amount of Si required to induce this change suggests that the domain boundaries are made of a local distortion of the silicene honeycomb lattice. The realization of a single domain sheet with structural and electronic properties close to those of the original striped state demonstrates the high structural flexibility of silicene.

One Health approach: A platform for intervention in emerging public health challenges of Kerala state

Directory of Open Access Journals (Sweden)

A. Sukumaran

2015-05-01

Full Text Available The authors, key functionaries in the Kerala state public health system, review the communicable disease scenario of the state for the past 4 years, and in the background of the One Health concept, opines that the re-emerged discipline is perfectly in tune with the current challenges of the state. The unique model of Kerala state is witnessing newer challenges in its public health arena: The rapidly increasing migrant workforce from relatively poorer states of India, rapid urbanization and its consequent stress on public health, unsolved issues of urban waste disposal, reemergence of many communicable diseases like malaria, more so, the falciparum type, emergence of many zoonotic diseases like Lyme disease, scrub typhus, and Kyasanur forest disease etc. Conventional zoonotic infections such as anthrax and brucellosis remain potential threat for human health as well. Rabies continued to cause major concern from mortality point of view, as well as major drainer of state’s budget every year. Leptospirosis has remained major burden among the communicable disease for the past 10 years, and the annual incidence ranged from 2 to 7 per 100,000 population. Having a large section of its people working in various agriculture and animal rearing occupations, the state has all risk factors for propagation of Leptospirosis, but lacks interdisciplinary collaboration in its control and prevention area, the author highlights major avenues for collaboration. Japanese encephalitis appeared as an epidemic in 2011 in two of the southern districts in Kerala, one of the districts being famous tourist spot for both humans, as well as migrant birds. There is ample scope for collaborative research on the source of the virus, and in the subsequent years, the disease had been detected in more districts. Lyme disease was reported for the first time in India, from one of the districts in Kerala, promptly investigated by a joint team from Human Public Health and Veterinary

Time-Domain Fluorescence Lifetime Imaging Techniques Suitable for Solid-State Imaging Sensor Arrays

Directory of Open Access Journals (Sweden)

Robert K. Henderson

2012-05-01

Full Text Available We have successfully demonstrated video-rate CMOS single-photon avalanche diode (SPAD-based cameras for fluorescence lifetime imaging microscopy (FLIM by applying innovative FLIM algorithms. We also review and compare several time-domain techniques and solid-state FLIM systems, and adapt the proposed algorithms for massive CMOS SPAD-based arrays and hardware implementations. The theoretical error equations are derived and their performances are demonstrated on the data obtained from 0.13 μm CMOS SPAD arrays and the multiple-decay data obtained from scanning PMT systems. In vivo two photon fluorescence lifetime imaging data of FITC-albumin labeled vasculature of a P22 rat carcinosarcoma (BD9 rat window chamber are used to test how different algorithms perform on bi-decay data. The proposed techniques are capable of producing lifetime images with enough contrast.

Advances in the Study of Post-Communist States and Public Administrations

DEFF Research Database (Denmark)

Vanhuysse, Pieter

2008-01-01

I introduce a 5-article special section that discusses recent advances in the study of postcommunist states and public administrations based around Anna Gzymala-Busse's Rebuilding Leviathan and Conor O'Dwyer's Runaway State Building. In addition to contributions by these two authors, it contains...... an editorial introduction by Pieter Vanhuysse, who argues that these books combine rigorous theory building with innovative empirical analysis of the size and effectiveness of CEE administrative bureaucracy, and make inroads by pointing to the nature of party competition as an important factor driving CEE...

Public relations in the State Office for Nuclear Safety

International Nuclear Information System (INIS)

Prochazkova, Radka

2000-01-01

The State Office for Nuclear Safety (SONS) is a government agency. The Office is headed by a chairperson who is appointed by the Czech Government. The Office has got its own budget and reports directly to the Czech Government. SONS was established in 1993 and continued activities of the former Czechoslovak Commission for Atomic Energy. SONS main activity is the central administration and supervision of the peaceful utilization of nuclear power and ionizing radiation and in the field of radiation protection. SONS is regulated mainly by the Atomic Act. A separate department of Public Relations was established last year in SONS especially due to the enactment of the statutory obligation of government agencies to render information. Basic P.R. communication means in the field of external communication include: Information Center; Internet; Press Releases; Publications - publishing regularly or for topical events; Seminars; Meetings; Press conferences; Editorial articles; Answering questions

Informatics and communication in a state public health department: a case study.

Science.gov (United States)

Hills, Rebecca A; Turner, Anne M

2008-11-06

State and local health departments are witnessing growth in the area of informatics. As new informatics projects commence, existing methods of communication within the health department may not be sufficient. We gathered information about roles and communication between a development team and a user group working simultaneously on an informatics project in a state public health department in an effort to better define how communication and role definition is best used within an informatics project.

Claiming justice: knowing mental illness in the public art of Anna Schuleit's 'Habeas Corpus' and 'Bloom'.

Science.gov (United States)

Bell, Susan E

2011-05-01

This study investigates two public art performances by artist Anna Schuleit in the early 2000s commemorating the life and history of two state hospitals ('asylums') in Massachusetts and the people who built, worked, and were patients in them. Public art is made for and sited in the public domain, outside, freely accessible, frequently collaborative, and often ephemeral. This study addresses a series of questions: What can public art 'do' for understanding mental illness? What use is a public art project for those living with (and caring for those who live with) mental illness? How can a public work of art sustain and portray meaning in an expressive way, open up a shared discursive space, and demand witness through embodiment?

CDC's National Environmental Public Health Tracking Program in Action: Case Studies From State and Local Health Departments.

Science.gov (United States)

Eatman, Shana; Strosnider, Heather M

The Centers for Disease Control and Prevention's (CDC's) National Environmental Public Health Tracking Program (Tracking Program) is a multidisciplinary collaboration that involves the ongoing collection, integration, analysis, interpretation, and dissemination of data from environmental hazard monitoring, human exposure surveillance, and health effects surveillance. With a renewed focus on data-driven decision-making, the CDC's Tracking Program emphasizes dissemination of actionable data to public health practitioners, policy makers, and communities. The CDC's National Environmental Public Health Tracking Network (Tracking Network), a Web-based system with components at the national, state, and local levels, houses environmental public health data used to inform public health actions (PHAs) to improve community health. This article serves as a detailed landscape on the Tracking Program and Tracking Network and the Tracking Program's leading performance measure, "public health actions." Tracking PHAs are qualitative statements addressing a local problem or situation, the role of the state or local Tracking Program, how the problem or situation was addressed, and the action taken. More than 400 PHAs have been reported by funded state and local health departments since the Tracking Program began collecting PHAs in 2005. Three case studies are provided to illustrate the use of the Tracking Program resources and data on the Tracking Network, and the diversity of actions taken. Through a collaborative network of experts, data, and tools, the Tracking Program and its Tracking Network are actively informing state and local PHAs. In a time of competing priorities and limited funding, PHAs can serve as a powerful tool to advance environmental public health practice.

Public Health System Research in Public Health Emergency Preparedness in the United States (2009-2015): Actionable Knowledge Base.

Science.gov (United States)

Savoia, Elena; Lin, Leesa; Bernard, Dottie; Klein, Noah; James, Lyndon P; Guicciardi, Stefano

2017-09-01

In 2008, the Institute of Medicine released a letter report identifying 4 research priority areas for public health emergency preparedness in public health system research: (1) enhancing the usefulness of training, (2) improving timely emergency communications, (3) creating and maintaining sustainable response systems, and (4) generating effectiveness criteria and metrics. To (1) identify and characterize public health system research in public health emergency preparedness produced in the United States from 2009 to 2015, (2) synthesize research findings and assess the level of confidence in these findings, and (3) describe the evolution of knowledge production in public health emergency preparedness system research. Search Methods and Selection Criteria. We reviewed and included the titles and abstracts of 1584 articles derived from MEDLINE, EMBASE, and gray literature databases that focused on the organizational or financial aspects of public health emergency preparedness activities and were grounded on empirical studies. We included 156 articles. We appraised the quality of the studies according to the study design. We identified themes during article analysis and summarized overall findings by theme. We determined level of confidence in the findings with the GRADE-CERQual tool. Thirty-one studies provided evidence on how to enhance the usefulness of training. Results demonstrated the utility of drills and exercises to enhance decision-making capabilities and coordination across organizations, the benefit of cross-sector partnerships for successfully implementing training activities, and the value of integrating evaluation methods to support training improvement efforts. Thirty-six studies provided evidence on how to improve timely communications. Results supported the use of communication strategies that address differences in access to information, knowledge, attitudes, and practices across segments of the population as well as evidence on specific

United States of America Department of Energy Environmental Management Advisory Committee Public Meeting

Energy Technology Data Exchange (ETDEWEB)

1993-12-01

This reports contains documentation of presentations given at the United States of America Department of Energy Environmental Management Advisory Committee Public Meeting held December 14--15, 1993 in Alexandria, Virginia.

Domains in Ferroic Crystals and Thin Films

CERN Document Server

Tagantsev, Alexander K; Fousek, Jan

2010-01-01

Domains in Ferroic Crystals and Thin Films presents experimental findings and theoretical understanding of ferroic (non-magnetic) domains developed during the past 60 years. It addresses the situation by looking specifically at bulk crystals and thin films, with a particular focus on recently-developed microelectronic applications and methods for observation of domains with techniques such as scanning force microscopy, polarized light microscopy, scanning optical microscopy, electron microscopy, and surface decorating techniques. Domains in Ferroic Crystals and Thin Films covers a large area of material properties and effects connected with static and dynamic properties of domains, which are extremely relevant to materials referred to as ferroics. In most solid state physics books, one large group of ferroics is customarily covered: those in which magnetic properties play a dominant role. Numerous books are specifically devoted to magnetic ferroics and cover a wide spectrum of magnetic domain phenomena. In co...

The individual face to face with public health: a conflict of interests or a conflict of conditions?

Directory of Open Access Journals (Sweden)

Janusz Sytnik-Czetwertyński

2016-02-01

Abstract The freedom of man and the freedom of the citizen are two entirely different domains. By nature, man is created for freedom, yet he does not possess the ability to effectively provide himself with a feeling of security. Man is therefore forced to negotiate, and in exchange for the abandonment of certain rights to freedom, receives a guarantee of relative peace. In order to enforce its obligations, the state is sometimes forced, in the name of the public good, to pacify the intentions of the individual and enforce pro-social actions. The issue discussed here is therefore reduced to the following: is the domain of public health one of those which should remain under the complete, or merely partial, control of the state (such as defence for instance, or should it remain open to the rights and demands of citizens?   The conclusion seems to be the following: the public health perspective is a social one and there is therefore little room for a wide-ranging dialogue with the individual. On the other hand, the system cannot close itself entirely to the reactions of society, since it is supposed to serve people and not its own ideals. It must possess the capacity to not lose sight of people and their problems, so often defying any prognoses and expectations, within the process of enacting public health policy.     Key words: face to face, public health.

On the study of the magnetic domain pattern via the initial magnetization curve

International Nuclear Information System (INIS)

Wu, T.

1997-01-01

This study inquires into the relationships between the initial magnetization curve and the magnetic domain pattern in the demagnetized states for amorphous TbFeCo as well as multilayered Co/Pd thin film samples. This was done specifically through an investigation of different demagnetized states of samples demagnetized by a variety of methods. The magnetic domain pattern for the sample demagnetized by an in-plane magnetic field and for the sample demagnetized by a perpendicular magnetic field was found to be quite different even though both states have zero magnetization. The former state has denser and finer domains than the latter. In addition, both states were studied in light of the initial magnetization curves obtained by measurements of the magneto-optic Kerr effect and the extraordinary Hall effect. Moreover, the initial magnetization for the fine domains increases with an increase in magnetic field, while for the coarse domains, the initial magnetization remains at zero for magnetic field below coercivity H c , then rises sharply to saturated magnetization when magnetic field is nearly equal to H c . copyright 1997 American Institute of Physics

Photoinduced Domain Pattern Transformation in Ferroelectric-Dielectric Superlattices

Energy Technology Data Exchange (ETDEWEB)

Ahn, Youngjun; Park, Joonkyu; Pateras, Anastasios; Rich, Matthew B.; Zhang, Qingteng; Chen, Pice; Yusuf, Mohammed H.; Wen, Haidan; Dawber, Matthew; Evans, Paul G.

2017-07-01

The nanodomain pattern in ferroelectric/dielectric superlattices transforms to a uniform polarization state under above-bandgap optical excitation. X-ray scattering reveals a disappearance of domain diffuse scattering and an expansion of the lattice. The reappearance of the domain pattern occurs over a period of seconds at room temperature, suggesting a transformation mechanism in which charge carriers in long-lived trap states screen the depolarization field. A Landau-Ginzburg-Devonshire model predicts changes in lattice parameter and a critical carrier concentration for the transformation.

Suitability of public use secondary data sets to study multiple activities.

Science.gov (United States)

Putnam, Michelle; Morrow-Howell, Nancy; Inoue, Megumi; Greenfield, Jennifer C; Chen, Huajuan; Lee, YungSoo

2014-10-01

The aims of this study were to inventory activity items within and across U.S. public use data sets, to identify gaps in represented activity domains and challenges in interpreting domains, and to assess the potential for studying multiple activity engagement among older adults using existing data. We engaged in content analysis of activity measures of 5U.S. public use data sets with nationally representative samples of older adults. Data sets included the Health & Retirement Survey (HRS), Americans' Changing Lives Survey (ACL), Midlife in the United States Survey (MIDUS), the National Health Interview Survey (NHIS), and the Panel Study of Income Dynamics survey (PSID). Two waves of each data set were analyzed. We identified 13 distinct activity domains across the 5 data sets, with substantial differences in representation of those domains among the data sets, and variance in the number and type of activity measures included in each. Our findings indicate that although it is possible to study multiple activity engagement within existing data sets, fuller sets of activity measures need to be developed in order to evaluate the portfolio of activities older adults engage in and the relationship of these portfolios to health and wellness outcomes. Importantly, clearer conceptual models of activity broadly conceived are required to guide this work. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

U.S. EPA Environmental Quality Index - Air Domain

Science.gov (United States)

This is an invited presentation by Region 5, Air Office, who asked me to provide an overview of the Air Domain and health results associated with the Air Domain of the Environmental Quality Index. Region 5 is hosting an Air Toxics meeting for its member states (Ohio, Michigan, I...

The Odd One Out? Revisiting the Belgian Welfare State

Directory of Open Access Journals (Sweden)

Cor Wagenaar

2014-08-01

Full Text Available Michael Ryckewaert publication Building the Economic Backbone of the Belgian Welfare State. Infrastructure, planning and architecture 1945-1973 describes the evolution of the welfare state and Belgium, more specifically its spatial characteristics. This by now historical socio-political model had decidedly collectivist traits, culminating in the provision of social security networks and a vast expansion of the public domain. If collectivism was one of the key elements of the welfare state, the absence of centralized planning appears to make the Belgian variant somewhat problematic.Whereas in countries like the Netherlands, Germany and France, modernism became the house style of the welfare state, thanks to the massive investments in public housing, this did not happen in Belgium. Here, the De Taeye Act of 1948 sponsored the construction of individual, detached houses; not surprisingly, most clients preferred traditional architecture and refrained from modern experiments. Industrial parks, office buildings and shops, on the other hand, developed into the cornerstones of Belgian modern architecture after 1945. Both the low-density sprawl and the industrial parks depend heavily on the use of the car, which was accommodated by the construction of a network of highways.

Top priorities for alcohol regulators in the United States: protecting public health or the alcohol industry?

Science.gov (United States)

Mart, Sarah M

2012-02-01

This paper describes alcohol industry involvement in the 2010 annual conference proceedings of the National Conference of State Liquor Administrators (NCSLA) in the United States. The author attended the conference, observed conference attendees and panelists and identified key themes in the panel sessions. The NCSLA Annual Meeting took place 20-24 June 2010 in New Orleans, Louisiana. NCSLA meeting attendees and panelists were professionals from state alcohol control systems; federal government agencies; and companies representing the alcohol industry. The total number of conference attendees and participants were counted as well as the number of attendees and participants from regulator, industry and public health sectors. More than two-thirds (72.2%) of the 187 conference attendees were from alcohol producers, importers, wholesalers, retailers or their attorneys. Nearly two-thirds (65.0%) of the 40 panelists were from the alcohol industry. The author of this paper was the only attendee, and the only panelist, representing public health policy. The National Conference of State Liquor Administrators in the United States is dominated by the global companies that produce, import, distribute and sell alcohol, highlighting a lack of public health considerations within the Association's liquor control agenda [corrected]. © 2012 Alcohol Justice.

A multistate examination of partnership activity among local public health systems using the National Public Health Performance Standards.

Science.gov (United States)

Barnes, Priscilla A; Curtis, Amy B; Hall-Downey, Laura; Moonesinghe, Ramal

2012-01-01

This study examines whether partnership-related measures in the second version of the National Public Health Performance Standards (NPHPS) are useful in evaluating level of activity as well as identifying latent constructs that exist among local public health systems (LPHSs). In a sample of 110 LPHSs, descriptive analysis was conducted to determine frequency and percentage of 18 partnership-related NPHPS measures. Principal components factor analysis was conducted to identify unobserved characteristics that promote effective partnerships among LPHSs. Results revealed that 13 of the 18 measures were most frequently reported at the minimal-moderate level (conducted 1%-49% of the time). Coordination of personal health and social services to optimize access (74.6%) was the most frequently reported measure at minimal-moderate levels. Optimal levels (conducted >75% of the time) were reported most frequently in 2 activities: participation in emergency preparedness coalitions and local health departments ensuring service provision by working with state health departments (67% and 61% of respondents, respectively) and the least optimally reported activity was review partnership effectiveness (4% of respondents). Factor analysis revealed categories of partnership-related measures in 4 domains: resources and activities contributing to relationship building, evaluating community leadership activities, research, and state and local linkages to support public health activities. System-oriented public health assessments may have questions that serve as proxy measures to examine levels of interorganizational partnerships. Several measures from the NPHPS were useful in establishing a national baseline of minimal and optimal activity levels as well as identifying factors to enhance the delivery of the 10 essential public health services among organizations and individuals in public health systems.

Integrative Spatial Data Analytics for Public Health Studies of New York State.

Science.gov (United States)

Chen, Xin; Wang, Fusheng

2016-01-01

Increased accessibility of health data made available by the government provides unique opportunity for spatial analytics with much higher resolution to discover patterns of diseases, and their correlation with spatial impact indicators. This paper demonstrated our vision of integrative spatial analytics for public health by linking the New York Cancer Mapping Dataset with datasets containing potential spatial impact indicators. We performed spatial based discovery of disease patterns and variations across New York State, and identify potential correlations between diseases and demographic, socio-economic and environmental indicators. Our methods were validated by three correlation studies: the correlation between stomach cancer and Asian race, the correlation between breast cancer and high education population, and the correlation between lung cancer and air toxics. Our work will allow public health researchers, government officials or other practitioners to adequately identify, analyze, and monitor health problems at the community or neighborhood level for New York State.

The PH Domain of PDK1 Exhibits a Novel, Phospho-Regulated Monomer-Dimer Equilibrium With Important Implications for Kinase Domain Activation: Single Molecule and Ensemble Studies†

Science.gov (United States)

Ziemba, Brian P.; Pilling, Carissa; Calleja, Véronique; Larijani, Banafshé; Falke, Joseph J.

2013-01-01

Phosphoinositide-Dependent Kinase-1 (PDK1) is an essential master kinase recruited to the plasma membrane by the binding of its C-terminal PH domain to the signaling lipid phosphatidylinositol-3,4-5-trisphosphate (PIP3). Membrane binding leads to PDK1 phospho-activation, but despite the central role of PDK1 in signaling and cancer biology this activation mechanism remains poorly understood. PDK1 has been shown to exist as a dimer in cells, and one crystal structure of its isolated PH domain exhibits a putative dimer interface. It has been proposed that phosphorylation of PH domain residue T513 (or the phospho-mimetic T513E mutation) may regulate a novel PH domain dimer-monomer equilibrium, thereby converting an inactive PDK1 dimer to an active monomer. However, the oligomeric state(s) of the PH domain on the membrane have not yet been determined, nor whether a negative charge at position 513 is sufficient to regulate its oligomeric state. The present study investigates the binding of purified WT and T513E PDK1 PH domains to lipid bilayers containing the PIP3 target lipid, using both single molecule and ensemble measurements. Single molecule analysis of the brightness of fluorescent PH domain shows that the PIP3-bound WT PH domain on membranes is predominantly dimeric, while the PIP3-bound T513E PH domain is monomeric, demonstrating that negative charge at the T513 position is sufficient to dissociate the PH domain dimer and is thus likely to play a central role in PDK1 monomerization and activation. Single molecule analysis of 2-D diffusion of PH domain-PIP3 complexes reveals that the dimeric WT PH domain diffuses at the same rate a single lipid molecule, indicating that only one of its two PIP3 binding sites is occupied and there is little protein penetration into the bilayer as observed for other PH domains. The 2-D diffusion of T513E PH domain is slower, suggesting the negative charge disrupts local structure in a way that enables greater protein insertion into

75 FR 56911 - Request for Public Comment on the United States Standards for Corn

Science.gov (United States)

2010-09-17

... Public Comment on the United States Standards for Corn AGENCY: Grain Inspection, Packers and Stockyards... Standards and grading procedures for corn under the United States Grain Standards Act (USGSA). Since the standards were last revised, the use of corn for ethanol and the number of different varieties of corn has...

Epithelium-Stroma Classification via Convolutional Neural Networks and Unsupervised Domain Adaptation in Histopathological Images.

Science.gov (United States)

Huang, Yue; Zheng, Han; Liu, Chi; Ding, Xinghao; Rohde, Gustavo K

2017-11-01

Epithelium-stroma classification is a necessary preprocessing step in histopathological image analysis. Current deep learning based recognition methods for histology data require collection of large volumes of labeled data in order to train a new neural network when there are changes to the image acquisition procedure. However, it is extremely expensive for pathologists to manually label sufficient volumes of data for each pathology study in a professional manner, which results in limitations in real-world applications. A very simple but effective deep learning method, that introduces the concept of unsupervised domain adaptation to a simple convolutional neural network (CNN), has been proposed in this paper. Inspired by transfer learning, our paper assumes that the training data and testing data follow different distributions, and there is an adaptation operation to more accurately estimate the kernels in CNN in feature extraction, in order to enhance performance by transferring knowledge from labeled data in source domain to unlabeled data in target domain. The model has been evaluated using three independent public epithelium-stroma datasets by cross-dataset validations. The experimental results demonstrate that for epithelium-stroma classification, the proposed framework outperforms the state-of-the-art deep neural network model, and it also achieves better performance than other existing deep domain adaptation methods. The proposed model can be considered to be a better option for real-world applications in histopathological image analysis, since there is no longer a requirement for large-scale labeled data in each specified domain.

Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion

International Nuclear Information System (INIS)

Habenstein, Birgit; Wasmer, Christian; Bousset, Luc; Sourigues, Yannick; Schütz, Anne; Loquet, Antoine; Meier, Beat H.; Melki, Ronald; Böckmann, Anja

2011-01-01

We present the de novo resonance assignments for the crystalline 33 kDa C-terminal domain of the Ure2 prion using an optimized set of five 3D solid-state NMR spectra. We obtained, using a single uniformly 13 C, 15 N labeled protein sample, sequential chemical-shift information for 74% of the N, Cα, Cβ triples, and for 80% of further side-chain resonances for these spin systems. We describe the procedures and protocols devised, and discuss possibilities and limitations of the assignment of this largest protein assigned today by solid-state NMR, and for which no solution-state NMR shifts were available. A comparison of the NMR chemical shifts with crystallographic data reveals that regions with high crystallographic B-factors are particularly difficult to assign. While the secondary structure elements derived from the chemical shift data correspond mainly to those present in the X-ray crystal structure, we detect an additional helical element and structural variability in the protein crystal, most probably originating from the different molecules in the asymmetric unit, with the observation of doubled resonances in several parts, including entire stretches, of the protein. Our results provide the point of departure towards an atomic-resolution structural analysis of the C-terminal Ure2p domain in the context of the full-length prion fibrils.

Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion

Energy Technology Data Exchange (ETDEWEB)

Habenstein, Birgit [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France); Wasmer, Christian [Harvard Medical School (United States); Bousset, Luc; Sourigues, Yannick [UPR 3082 CNRS, Laboratoire d' Enzymologie et Biochimie Structurales (France); Schuetz, Anne [ETH Zurich, Physical Chemistry (Switzerland); Loquet, Antoine [Max Planck Institute for Biophysical Chemistry (Germany); Meier, Beat H., E-mail: beme@ethz.ch [ETH Zurich, Physical Chemistry (Switzerland); Melki, Ronald, E-mail: melki@lebs.cnrs-gif.fr [UPR 3082 CNRS, Laboratoire d' Enzymologie et Biochimie Structurales (France); Boeckmann, Anja, E-mail: a.bockmann@ibcp.fr [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France)

2011-11-15

We present the de novo resonance assignments for the crystalline 33 kDa C-terminal domain of the Ure2 prion using an optimized set of five 3D solid-state NMR spectra. We obtained, using a single uniformly {sup 13}C, {sup 15}N labeled protein sample, sequential chemical-shift information for 74% of the N, C{alpha}, C{beta} triples, and for 80% of further side-chain resonances for these spin systems. We describe the procedures and protocols devised, and discuss possibilities and limitations of the assignment of this largest protein assigned today by solid-state NMR, and for which no solution-state NMR shifts were available. A comparison of the NMR chemical shifts with crystallographic data reveals that regions with high crystallographic B-factors are particularly difficult to assign. While the secondary structure elements derived from the chemical shift data correspond mainly to those present in the X-ray crystal structure, we detect an additional helical element and structural variability in the protein crystal, most probably originating from the different molecules in the asymmetric unit, with the observation of doubled resonances in several parts, including entire stretches, of the protein. Our results provide the point of departure towards an atomic-resolution structural analysis of the C-terminal Ure2p domain in the context of the full-length prion fibrils.

Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states

Energy Technology Data Exchange (ETDEWEB)

Bodenheimer, Annette M. [Molecular and Structural Biochemistry Department, North Carolina State University, Raleigh NC USA; Neutron Sciences Directorate, Oak Ridge National Laboratory, TN USA; Meilleur, Flora [Molecular and Structural Biochemistry Department, North Carolina State University, Raleigh NC USA; Neutron Sciences Directorate, Oak Ridge National Laboratory, TN USA

2016-11-07

Trichoderma reesei Cel7A efficiently hydrolyses cellulose. We report here the crystallographic structures of the wild-type TrCel7A catalytic domain (CD) in an open state and, for the first time, in a closed state. Molecular dynamics (MD) simulations indicate that the loops along the CD tunnel move in concerted motions. Together, the crystallographic and MD data suggest that the CD cycles between the tense and relaxed forms that are characteristic of work producing enzymes. Analysis of the interactions formed by R251 provides a structural rationale for the concurrent decrease in product inhibition and catalytic efficiency measured for product-binding site mutants.

Containment Domains: A Scalable, Efficient and Flexible Resilience Scheme for Exascale Systems

Directory of Open Access Journals (Sweden)

Jinsuk Chung

2013-01-01

Full Text Available This paper describes and evaluates a scalable and efficient resilience scheme based on the concept of containment domains. Containment domains are a programming construct that enable applications to express resilience needs and to interact with the system to tune and specialize error detection, state preservation and restoration, and recovery schemes. Containment domains have weak transactional semantics and are nested to take advantage of the machine and application hierarchies and to enable hierarchical state preservation, restoration and recovery. We evaluate the scalability and efficiency of containment domains using generalized trace-driven simulation and analytical analysis and show that containment domains are superior to both checkpoint restart and redundant execution approaches.

Variation in exemptions to school immunization requirements among New York State private and public schools.

Science.gov (United States)

Lai, Yun-Kuang; Nadeau, Jessica; McNutt, Louise-Anne; Shaw, Jana

2014-12-12

School immunization requirements have ensured high vaccination rates and have helped to control vaccine-preventable diseases. However, vaccine exemptions have increased in the last decade. This study compared New York State private versus public schools with respect to medical and religious exemption rates. This retrospective study utilizes New York State Department of Health Immunization Survey data from the 2003 through 2012 academic years. Schools were categorized as private or public, the former further categorized by religious affiliation. Rates of medical and religious vaccine exemptions were compared by school category. From 2003 to 2012, religious exemptions increased in private and public schools from 0.63% to 1.35% and 0.17% to 0.29% (Spearman's R: 0.89 and 0.81), respectively. Among private schools, increases in religious exemption rates during the study period were observed in Catholic/Eastern Orthodox, Protestant/Other Christian, Jewish, and secular schools (Spearman's R=0.66, 0.99, 0.89, and 0.93), respectively. Exemption rate ratios in private schools compared to public schools were 1.39 (95% CI 1.15-1.68) for medical and 3.94 (95% CI: 3.20-4.86) for religious exemptions. Among private school students, all school types except for Catholic/Eastern Orthodox and Episcopal affiliates were more likely to report religious exemptions compared to children in public schools. Medical and religious exemption rates increased over time and higher rates were observed among New York State private schools compared to public schools. Low exemption rates are critical to minimize disease outbreaks in the schools and their community. Copyright © 2014 Elsevier Ltd. All rights reserved.

Coherent states in quantum physics

CERN Document Server

Gazeau, Jean-Pierre

2009-01-01

This self-contained introduction discusses the evolution of the notion of coherent states, from the early works of Schrödinger to the most recent advances, including signal analysis. An integrated and modern approach to the utility of coherent states in many different branches of physics, it strikes a balance between mathematical and physical descriptions.Split into two parts, the first introduces readers to the most familiar coherent states, their origin, their construction, and their application and relevance to various selected domains of physics. Part II, mostly based on recent original results, is devoted to the question of quantization of various sets through coherent states, and shows the link to procedures in signal analysis. Title: Coherent States in Quantum Physics Print ISBN: 9783527407095 Author(s): Gazeau, Jean-Pierre eISBN: 9783527628292 Publisher: Wiley-VCH Dewey: 530.12 Publication Date: 23 Sep, 2009 Pages: 360 Category: Science, Science: Physics LCCN: Language: English Edition: N/A LCSH:

The association of state law to physical education time allocation in US public schools.

Science.gov (United States)

Perna, Frank M; Oh, April; Chriqui, Jamie F; Mâsse, Louise C; Atienza, Audie A; Nebeling, Linda; Agurs-Collins, Tanya; Moser, Richard P; Dodd, Kevin W

2012-08-01

We examined whether public schools in states with specific and stringent physical education (PE) laws, as assessed by the Physical Education-Related State Policy Classification System (PERSPCS), available on the Classification of Laws Associated with School Students (C.L.A.S.S.) Web site, reported more weekly PE time in the most recent School Health Policies and Programs Survey (SHPPS). Schools (n=410) were grouped by their state's PERSPCS time requirement scores (none, nonspecific requirement, or specific requirement). Average weekly school-level PE was calculated using the SHPPS-reported PE minutes. Weighted analyses determined if PE minutes/week differed by PERSPCS group. Schools in states with specific requirement laws averaged over 27 and 60 more PE minutes/week at the elementary and middle school levels, respectively, compared with schools within states with nonspecific laws and over 40 and 60 more PE minutes per week, respectively, compared with elementary and middle schools in states with no laws. High school results were nonsignificant. Public health guidelines recommend at least 60 minutes of daily physical activity for children, and PE may further this goal. Strong codified law with specific time requirements for PE may be an important tool contributing toward adequate PE time and daily physical activity recommendations.

76 FR 38416 - Notice of Segregation of Public Lands in the States of Arizona, California, Colorado, Nevada, New...

Science.gov (United States)

2011-06-30

... Segregation of Public Lands in the States of Arizona, California, Colorado, Nevada, New Mexico, and Utah... laws, but not the mineral leasing or material sales acts, for a period of 2 years for the purpose of..., approximately 677,384 acres of public lands located in the States of Arizona, California, Colorado, Nevada, New...

Public-Private Partnership Potential in Property Management of Russia and Belarus Union State

Directory of Open Access Journals (Sweden)

A P Vihrjan

2010-09-01

Full Text Available The article describes a possibility of implementation of an institute of public-private partnership, mainly concessions, as a notable component of management system of the Union State's of Russia and Belarus Property.

Space science public outreach at Louisiana State University

Science.gov (United States)

Guzik, T.; Babin, E.; Cooney, W.; Giammanco, J.; Hartman, D.; McNeil, R.; Slovak, M.; Stacy, J.

Over the last seven years the Astronomy / Astrophysics group in the Department of Physics and Astronomy of Louisiana State University has developed an exten- sive Space Science education and public outreach program. This program includes the local park district (the Recreation and Park Commission for the Parish of East Baton Rouge, BREC), the local amateur astronomer group (the Baton Rouge As- tronomical Society, BRAS), the Louisiana Arts and Science Museum (LASM), and Southern University (SU, part of the largest HBCU system in the nation). Our effort has directly led to the development of the Highland Road Park Observatory (HRPO, http://www.bro.lsu.edu/hrpo) that supports student astronomy training at LSU and SU, amateur observations and a public program for adults and children, establishment of a series of teacher professional development workshops in astronomy and physics, and the "Robots for Internet Experiences (ROBIE)" project (http://www.bro.lsu.edu/) where we have several instruments (e.g. HAM radio, radio telescope, optical tele- scopes) that can be controlled over the internet by students and teachers in the class- room along with associated lessons developed by a teacher group. In addition, this year the LASM, will be opening a new planetarium / space theater in downtown Baton Rouge, Louisiana. We are currently working to bring live views of the heavens from the HRPO telescope to audiences attending planetarium shows and will be working closely with planetarium staff to develop shows that highlight LSU astronomy / space science research. During the presentation we will provide some details about our in- dividual projects, the overall structure of our program, establishing community links and some of the lessons we learned along the way. Finally, we would like to acknowl- edge NASA, Louisiana State University, the Louisiana Systemic Initiatives Program and the Louisiana Technology Innovation Fund for their support.

Public Debt, Public Investment and Economic Growth in Mexico

Directory of Open Access Journals (Sweden)

Isaac Sánchez-Juárez

2016-03-01

Full Text Available The primary objective of this article is to answer the following two research questions: has the growing public debt of state governments promoted increased public investment? If the answer is yes, then does any increase in public investment lead to more growth in the Mexican states? Dynamic Models of panel data and the Generalized Method of Moments, with information for 32 states from 1993 to 2012, were used for this purpose. The econometric results confirmed that public debt is positively correlated with public investment and that this in turn generates economic growth. This does not mean that a good economic policy strategy has been followed, since the marginal positive impact of public investment, and therefore the public debt on the production per person, is reduced (1% increase in the interaction between public investment and public debt variable causes a 0.0005% increase in economic growth. This suggests deviations from the debt contracted for purposes other than production, which could lead to a situation of unsustainability of state public finances in the medium term.

Economic Growth, Productivity, and Public Education Funding: Is South Carolina a Death Spiral State?

Science.gov (United States)

Driscoll, Lisa G.; Knoeppel, Robert C.; Della Sala, Matthew R.; Watson, Jim R.

2014-01-01

As a result of the Great Recession of 2007-2009, most states experienced declines in employment, consumer spending, and economic productivity (Alm, Buschman, and Sjoquist 2011). In turn, these events led to historic declines in state tax revenues (Mikesell and Mullins 2010; Boyd and Dadayan 2009), resulting in major cuts in public spending. Local…

Time-Domain Voltage Sag State Estimation Based on the Unscented Kalman Filter for Power Systems with Nonlinear Components

Directory of Open Access Journals (Sweden)

Rafael Cisneros-Magaña

2018-06-01

Full Text Available This paper proposes a time-domain methodology based on the unscented Kalman filter to estimate voltage sags and their characteristics, such as magnitude and duration in power systems represented by nonlinear models. Partial and noisy measurements from the electrical network with nonlinear loads, used as data, are assumed. The characteristics of voltage sags can be calculated in a discrete form with the unscented Kalman filter to estimate all the busbar voltages; being possible to determine the rms voltage magnitude and the voltage sag starting and ending time, respectively. Voltage sag state estimation results can be used to obtain the power quality indices for monitored and unmonitored busbars in the power grid and to design adequate mitigating techniques. The proposed methodology is successfully validated against the results obtained with the time-domain system simulation for the power system with nonlinear components, being the normalized root mean square error less than 3%.

Public-Private Partnerships (PPP on moulding state structures: The Non-Ergodic Africa

Directory of Open Access Journals (Sweden)

Fred Amonya

2016-10-01

Full Text Available Public-Private Partnerships (PPP is a ubiquitous reality. In Africa, the wave of PPP has hit states in their infancy – still moulding following only 50 years since independence. The common perspective of PPP on the realms of scholarship is transactional (focused on the delivery-end of infrastructure. This paper presents a deeper and broader perspective, and it is a distillate of a case study on PPP as a policy phenomenon. It dissects and illuminates the interaction between the forces of state formation and the wave of PPP hitting the continent. The lens of this case study is Institutional Rational Choice (IRC. The tools are a variety, comprising textual analysis, hermeneutics and econometrics – in keeping with the essence of case study (explication of reality in-situ. The product is not the orthodox generalization (claiming ‘the way’. Instead, the explication offers a viewpoint (and trigger questions on public space of Africa, while underpinning the non-ergodic character of that space

Characteristics of scientific web publications

DEFF Research Database (Denmark)

Thorlund Jepsen, Erik; Seiden, Piet; Ingwersen, Peter Emil Rerup

2004-01-01

were generated based on specifically selected domain topics that are searched for in three publicly accessible search engines (Google, AllTheWeb, and AltaVista). A sample of the retrieved hits was analyzed with regard to how various publication attributes correlated with the scientific quality...... of the content and whether this information could be employed to harvest, filter, and rank Web publications. The attributes analyzed were inlinks, outlinks, bibliographic references, file format, language, search engine overlap, structural position (according to site structure), and the occurrence of various...... types of metadata. As could be expected, the ranked output differs between the three search engines. Apparently, this is caused by differences in ranking algorithms rather than the databases themselves. In fact, because scientific Web content in this subject domain receives few inlinks, both Alta...

Liberalization of energy markets: local policies of public-private contractual relations; Liberalisation des marches energetiques: les politiques locales de relations contractuelles public-prive

Energy Technology Data Exchange (ETDEWEB)

Cahn, M; Schilken, P

2001-07-01

This state-of-the-art focusses on the contractual relations between the local authorities and the private sector in the domain of energy. In the past, specialized services were supplied and internally managed by utilities and monopolies, while today the same services are ensured by private companies selected according to their efficiency and competitiveness. In France, country of centralized tradition, such practices are not really developed while they are already in UK and Germany. This study gives an overview of the advantages of these practices using some examples taken in four domains: the helps to the choice of an electricity supplier and of the quality of power, the contracts of concessions of power distribution, the supply of energy advice services by external experts, and the helps for the investment in the domain of mastery of energy demand. Nine case-forms illustrate the experience of nine European countries in these public-private energy partnerships: Basel (CH), Berlin, Hagen and Heidelberg (DE), Brent, Leicester and Waltham Forest (GB), Graz (AT) and Jablonec (CZ). (J.S.)

Imbalances in the German public health system - numbers of state-certified occupational physicians and relation to socioeconomic data.

Science.gov (United States)

Gyo, Christoph; Boll, Michael; Brüggmann, Dörthe; Klingelhöfer, Doris; Quarcoo, David; Groneberg, David A

2016-01-01

State-certified occupational physicians who work as civil servants in the Federal Republic of Germany are key players in the German Public Health system. They control i.e. the legal compliance in occupational health and participate in the occupational disease procedures. Despite the role model function of the German Public health system for many developing countries, this area of Public health is debated to have been hampered in the past years by a disregard concerning structural developments. Different databases were screened for occupational health benchmarks. Obtained data were compared to socioeconomic data and indices were calculated. The overall numbers of State-certified occupational physicians decreased in Germany between 1992 and 2012 from 136 to 86 (63 %). On the single state level, the ratios of State-certified occupational physicians per 1 Mio. working population ranged from 8 for the state of Saarland to 0.8 for the state of North Rhine Westphalia. A general difference was found for old versus new German states. Also, large differences were present for the ratios of State-certified occupational physicians per 10 6 employees towards public debt per capita (€) and the ratios of State-certified occupational physicians per Gross Domestic Product (GDP) in the 16 German states in 2012. In striking contrast to the WHO document on the Occupational safety and health (OSH) system that states in its executive summary that the human and institutional capacities of the German occupational health system are very strong in both quantity and quality, we here show extreme imbalances present at the single state levels that developed over the past 20 years. With a regard to the increasing complexity of the economic system a reversal of this trend should be demanded.

Characterizing the Business Skills of the Public Health Workforce: Practical Implications From the Public Health Workforce Interests and Needs Survey (PH WINS).

Science.gov (United States)

Kornfeld, Julie; Sznol, Joshua; Lee, David

2015-01-01

Public health financial competencies are often overlooked or underrepresented in public health training programs. These skills are important for public health workforce members who are involved in managing resources and strategic planning and have been defined as key competencies by several national entities. To characterize business skills among state health agency employees and examine self-reported skill levels and their association with job satisfaction, worksite training and development opportunities, and annual salary. A cross-sectional survey, the Public Health Workforce Interests and Needs Survey (PH WINS), of state health agency central office employees was conducted in 2014. Multivariable logistic regression analyses, controlling for job classification, supervisory status, years of public health practice, annual compensation, educational attainment, geographic region, and sociodemographic status, were used to assess the relationship between business skills and training environment and job satisfaction. Linear regression was used to correlate business skills and annual compensation. A total of 10,246 state health agency staff completed a Web-based survey. Self-reported proficiency in business skills, job satisfaction, opportunities for training, and annual salary. The workforce reported high levels of proficiency in applying quality improvement concepts and managing change (67.5% and 69.2%, respectively). Half of the respondents reported proficiency in budget skills (49.3%). Participants who were proficient in applying quality improvement concepts were significantly more likely to report job satisfaction (OR = 1.27). A supportive training environment was significantly associated with business competencies (range of OR = 1.08-1.11). Managing change (β = .15) and budget skill proficiency (β = .37) were significantly associated with increased yearly compensation. Public health workers who self-report proficiency with business skills report increased job

Astronomy in the United States: Workforce Development and Public Engagement

Science.gov (United States)

Impey, Chris

2012-08-01

Astronomy workforce development and public engagement in the United States are described. The number of professional astronomers has grown by about a third in the past 25 years, to about 4000. Only one in four are faculty in an academic setting; the rest work in a wide range of public and private research institutes. PhD production has remained steady at about 200 per year. Women account for roughly half of BSc degrees and a third of PhD degrees, but their participation declines to about 10% at the level of full professor. Minorities are underrepresented by a substantial factor at all levels of the profession. In terms of public engagement, astronomy has unique advantages associated with its visual appeal and the large and active amateur astronomy community. The are 1400 public planetaria in the US, with another 110 in schools and universities. Astronomers have made good use of new media such as blogs and podcasts and social networks, but the biggest impact has been in the area of citizen science, where people with no technical background contribute directly to a research project by, for example, classifying galaxies. The International Year of Astronomy and the remarkable success of the Galileoscope have inspired large numbers of people to appreciate astronomy, contributing indirectly to the professional vitality of the field.

Structure of Concatenated HAMP Domains Provides a Mechanism for Signal Transduction

Energy Technology Data Exchange (ETDEWEB)

Airola, Michael V.; Watts, Kylie J.; Bilwes, Alexandrine M.; Crane, Brian R. (Cornell); (Lorma Linda U)

2010-08-23

HAMP domains are widespread prokaryotic signaling modules found as single domains or poly-HAMP chains in both transmembrane and soluble proteins. The crystal structure of a three-unit poly-HAMP chain from the Pseudomonas aeruginosa soluble receptor Aer2 defines a universal parallel four-helix bundle architecture for diverse HAMP domains. Two contiguous domains integrate to form a concatenated di-HAMP structure. The three HAMP domains display two distinct conformations that differ by changes in helical register, crossing angle, and rotation. These conformations are stabilized by different subsets of conserved residues. Known signals delivered to HAMP would be expected to switch the relative stability of the two conformations and the position of a coiled-coil phase stutter at the junction with downstream helices. We propose that the two conformations represent opposing HAMP signaling states and suggest a signaling mechanism whereby HAMP domains interconvert between the two states, which alternate down a poly-HAMP chain.

The Reflection of Social Values in Public School Reading Textbooks in the United States: A Critical Content Analysis

Science.gov (United States)

Stockdale, Christopher L.

2015-01-01

In light of the recently published Common Core State Standards Initiative, public school curriculum has once again come under scrutiny. While curriculum debates have taken place since the very beginnings of public schooling in the United States, too few have taken more than a passing notice of the textbooks that, in many cases, comprise the…

Convergence of the Policies for Promoting Total Quality Management in the Public Administrations of Balkan States – European Union Member States

Directory of Open Access Journals (Sweden)

Ani MATEI

2011-03-01

Full Text Available In the past three decades, total quality management (TQM has been appreciated as “fundamental modality in view to improve the activity in the public and private sectors” (Boyne and Walker, 2002, p. 1. For the time being, in public administrations, we witness an extension of the policies for promoting TQM, although the experiences have not always been positive.The European Administrative Space (EAS incorporates TQM, in different manners at national level, taking into consideration its recognised impact on the efficiency of public administration, one of EAS fundamental principles (Zurga, 2008, pp. 39-49. In the context of analysing EAS evolution, the administrative convergence will also comprise the convergence of TQM policies. In fact, the field literature (Hackman, Wageman, 1995 reveals, in the context of national TQM policy-making, the concepts of ”Convergent validity” and ”Discriminant validity”, reflecting ”the degree to which the version of TQM promulgated by the founders and observed in organizational practice share a common set of assumptions and prescriptions” (Hackman, Wageman, 1995, pp. 318-319.By a comparative analysis on TQM policies in the national public administrations of Balkan states, EU Member States: Greece, Cyprus, Slovenia, Bulgaria and Romania, the current paper aims to reveal the level of their convergence as well as the theoretical consistency of the conceptual and practical framework for TQM assertion.The comparative analysis will be based on a comprehensive vision on TQM, provided by Dean and Bowen (1994, Boyne and Walker (2002, namely its approach should be characterised on own principles, practices and techniques, grouped on customer focus, continuous improvement and team work (Boyne and Walker, 2002, pp. 4-5.The tradition on promoting TQM in public administration in the above-mentioned states is relatively recent: since 1990s – Cyprus, since 1995 – Greece and Slovenia, since 2000 – Bulgaria and

Lessons Learned in Promoting Evidence-Based Public Health: Perspectives from Managers in State Public Health Departments.

Science.gov (United States)

Allen, Peg; Jacob, Rebekah R; Lakshman, Meenakshi; Best, Leslie A; Bass, Kathryn; Brownson, Ross C

2018-03-02

Evidence-based public health (EBPH) practice, also called evidence-informed public health, can improve population health and reduce disease burden in populations. Organizational structures and processes can facilitate capacity-building for EBPH in public health agencies. This study involved 51 structured interviews with leaders and program managers in 12 state health department chronic disease prevention units to identify factors that facilitate the implementation of EBPH. Verbatim transcripts of the de-identified interviews were consensus coded in NVIVO qualitative software. Content analyses of coded texts were used to identify themes and illustrative quotes. Facilitator themes included leadership support within the chronic disease prevention unit and division, unit processes to enhance information sharing across program areas and recruitment and retention of qualified personnel, training and technical assistance to build skills, and the ability to provide support to external partners. Chronic disease prevention leaders' role modeling of EBPH processes and expectations for staff to justify proposed plans and approaches were key aspects of leadership support. Leaders protected staff time in order to identify and digest evidence to address the common barrier of lack of time for EBPH. Funding uncertainties or budget cuts, lack of political will for EBPH, and staff turnover remained challenges. In conclusion, leadership support is a key facilitator of EBPH capacity building and practice. Section and division leaders in public health agencies with authority and skills can institute management practices to help staff learn and apply EBPH processes and spread EBPH with partners.

Use of media and public-domain Internet sources for detection and assessment of plant health threats.

Science.gov (United States)

Thomas, Carla S; Nelson, Noele P; Jahn, Gary C; Niu, Tianchan; Hartley, David M

2011-09-05

Event-based biosurveillance is a recognized approach to early warning and situational awareness of emerging health threats. In this study, we build upon previous human and animal health work to develop a new approach to plant pest and pathogen surveillance. We show that monitoring public domain electronic media for indications and warning of epidemics and associated social disruption can provide information about the emergence and progression of plant pest infestation or disease outbreak. The approach is illustrated using a case study, which describes a plant pest and pathogen epidemic in China and Vietnam from February 2006 to December 2007, and the role of ducks in contributing to zoonotic virus spread in birds and humans. This approach could be used as a complementary method to traditional plant pest and pathogen surveillance to aid global and national plant protection officials and political leaders in early detection and timely response to significant biological threats to plant health, economic vitality, and social stability. This study documents the inter-relatedness of health in human, animal, and plant populations and emphasizes the importance of plant health surveillance.

Making the case: leveraging resources toward public health system improvement in Turning Point states.

Science.gov (United States)

Bekemeier, Betty; Riley, Catharine M; Padgett, Stephen M; Berkowitz, Bobbie

2007-01-01

Leveraging funds to sustain the efforts of a grant-funded initiative is often an explicit, or implicit, expectation in philanthropy. However, the magnitude of funds leveraged and the factors that facilitate success in leveraging are rarely researched. An example of one of these grant-funded initiatives is the National Turning Point Initiative. Twenty-one states received funding from The Robert Wood Johnson Foundation as part of this initiative to establish and implement strategic goals for achieving significant statewide public health system improvement through diverse, cross-sector partnerships. Leaders from 17 of these 21 states participated in a two-phased study regarding the leveraging of additional funds for their public health infrastructure improvement activities. This article reports on the second phase of the study. In this phase, key informant interviews were conducted to examine how leveraging of resources occurred as part of this large national initiative. Findings indicate that the combination of a comprehensive planning process and a broad-based partnership was crucial in securing resources to expand their efforts. The ability to strategically respond to unexpected events and opportunities also helped states use their plans and partnerships to "make the case" for additional resources to improve their public health infrastructure.

The structure and organization of local and state public health agencies in the U.S.: a systematic review.

Science.gov (United States)

Hyde, Justeen K; Shortell, Stephen M

2012-05-01

This systematic review provides a synthesis of the growing field of public health systems research related to the structure and organization of state and local governmental public health agencies. It includes an overview of research examining the influence of organizational characteristics on public health performance and health status and a summary of the strengths and gaps of the literature to date. Data were retrieved through an iterative process, beginning with key word searches in three publication databases (PubMed, JSTOR, Web of Science). Gray literature was searched through the use of Google Scholar™. Targeted searches on websites and key authors were also performed. Documents underwent an initial and secondary screening; they were retained if they contained information about local or state public health structure, organization, governance, and financing. 77 articles met the study criteria. Public health services are delivered by a mix of local, state, and tribal governmental and nongovernmental agencies and delivered through centralized (28%); decentralized (37%); or combined authority (35%). The majority of studies focused on organizational characteristics that are associated with public health performance based on the 10 Essential Public Health Services framework. Population size of jurisdiction served (>50,000); structure of authority (decentralized and mixed); per capita spending at the local level; some partnerships (academic, health services); and leadership of agency directors have been found to be related to public health performance. Fewer studies examined the relationship between organizational characteristics and health outcomes. Improvements in health outcomes are associated with an increase in local health department expenditures, FTEs per capita, and location of health department within local networks. Public health systems in the U.S. face a number of critical challenges, including limited organizational capacity and financial resources

A Public Health Analysis of the Proposed Resolution of [the 1997 United States] Tobacco Litigation

OpenAIRE

Fox, Brion J. J.D.; Lightwood, James M. Ph.D.; Glantz, Stanton A. Ph.D.

1998-01-01

The proposed tobacco settlement agreement, as negotiated by some state attorneys general and the tobacco industry that was made public on June 20, 1997 (Appendix F), raises a complex array of public health, public policy, legal and economic issues. It was intended to be a blueprint for national tobacco control legislation that would end the most important litigation current and potential against the tobacco industry. As with most complex legislation, the deal, after it was announced, underwen...

Small-angle X-ray scattering analysis reveals the ATP-bound monomeric state of the ATPase domain from the homodimeric MutL endonuclease, a GHKL phosphotransferase superfamily protein.

Science.gov (United States)

Iino, Hitoshi; Hikima, Takaaki; Nishida, Yuya; Yamamoto, Masaki; Kuramitsu, Seiki; Fukui, Kenji

2015-05-01

DNA mismatch repair is an excision system that removes mismatched bases chiefly generated by replication errors. In this system, MutL endonucleases direct the excision reaction to the error-containing strand of the duplex by specifically incising the newly synthesized strand. Both bacterial homodimeric and eukaryotic heterodimeric MutL proteins belong to the GHKL ATPase/kinase superfamily that comprises the N-terminal ATPase and C-terminal dimerization regions. Generally, the GHKL proteins show large ATPase cycle-dependent conformational changes, including dimerization-coupled ATP binding of the N-terminal domain. Interestingly, the ATPase domain of human PMS2, a subunit of the MutL heterodimer, binds ATP without dimerization. The monomeric ATP-bound state of the domain has been thought to be characteristic of heterodimeric GHKL proteins. In this study, we characterized the ATP-bound state of the ATPase domain from the Aquifex aeolicus MutL endonuclease, which is a homodimeric GHKL protein unlike the eukaryotic MutL. Gel filtration, dynamic light scattering, and small-angle X-ray scattering analyses clearly showed that the domain binds ATP in a monomeric form despite its homodimeric nature. This indicates that the uncoupling of dimerization and ATP binding is a common feature among bacterial and eukaryotic MutL endonucleases, which we suggest is closely related to the molecular mechanisms underlying mismatch repair.

A role for chromatin topology in imprinted domain regulation.

Science.gov (United States)

MacDonald, William A; Sachani, Saqib S; White, Carlee R; Mann, Mellissa R W

2016-02-01

Recently, many advancements in genome-wide chromatin topology and nuclear architecture have unveiled the complex and hidden world of the nucleus, where chromatin is organized into discrete neighbourhoods with coordinated gene expression. This includes the active and inactive X chromosomes. Using X chromosome inactivation as a working model, we utilized publicly available datasets together with a literature review to gain insight into topologically associated domains, lamin-associated domains, nucleolar-associating domains, scaffold/matrix attachment regions, and nucleoporin-associated chromatin and their role in regulating monoallelic expression. Furthermore, we comprehensively review for the first time the role of chromatin topology and nuclear architecture in the regulation of genomic imprinting. We propose that chromatin topology and nuclear architecture are important regulatory mechanisms for directing gene expression within imprinted domains. Furthermore, we predict that dynamic changes in chromatin topology and nuclear architecture play roles in tissue-specific imprint domain regulation during early development and differentiation.

Generating social capital through public health leadership training: a six-year assessment.

Science.gov (United States)

Hawley, Suzanne R; St Romain, Theresa; Rempel, Scott L; Orr, Shirley A; Molgaard, Craig A

2012-08-01

Social capital, or a sense of partnership leading to shared goals, provides a means for addressing today's public health workforce challenges. This concept is particularly important in underserved rural areas, though efforts to intentionally generate social capital have been limited. Within the rural state of Kansas, the Kansas Public Health Leadership Institute (KPHLI) has implemented a social capital pre/post assessment to quantify the impact of KPHLI training on social capital within the state's decentralized public health system. This paper discusses 38 assessment items related to bonding, bridging and linking social capital. The assessment was completed pre and post training by 130 of 148 scholars (87.8%) in six KPHLI training cycles. Data were analyzed using Wilcoxon paired t-tests in SPSS. Thirty-five of 38 items demonstrated statistically significant increases at post-test, across all 10 sub-domains. Leadership training by the KPHLI fosters quantifiable increases in characteristics of social capital, which are essential for public health systems to cope with increased workforce demands and prepare for accreditation. This study represents a key first step in examining the deliberate generation of social capital within a decentralized rural environment.

Beyond cross-domain learning: Multiple-domain nonnegative matrix factorization

KAUST Repository

Wang, Jim Jing-Yan; Gao, Xin

2014-01-01

Traditional cross-domain learning methods transfer learning from a source domain to a target domain. In this paper, we propose the multiple-domain learning problem for several equally treated domains. The multiple-domain learning problem assumes that samples from different domains have different distributions, but share the same feature and class label spaces. Each domain could be a target domain, while also be a source domain for other domains. A novel multiple-domain representation method is proposed for the multiple-domain learning problem. This method is based on nonnegative matrix factorization (NMF), and tries to learn a basis matrix and coding vectors for samples, so that the domain distribution mismatch among different domains will be reduced under an extended variation of the maximum mean discrepancy (MMD) criterion. The novel algorithm - multiple-domain NMF (MDNMF) - was evaluated on two challenging multiple-domain learning problems - multiple user spam email detection and multiple-domain glioma diagnosis. The effectiveness of the proposed algorithm is experimentally verified. © 2013 Elsevier Ltd. All rights reserved.

Beyond cross-domain learning: Multiple-domain nonnegative matrix factorization

KAUST Repository

Wang, Jim Jing-Yan

2014-02-01

Traditional cross-domain learning methods transfer learning from a source domain to a target domain. In this paper, we propose the multiple-domain learning problem for several equally treated domains. The multiple-domain learning problem assumes that samples from different domains have different distributions, but share the same feature and class label spaces. Each domain could be a target domain, while also be a source domain for other domains. A novel multiple-domain representation method is proposed for the multiple-domain learning problem. This method is based on nonnegative matrix factorization (NMF), and tries to learn a basis matrix and coding vectors for samples, so that the domain distribution mismatch among different domains will be reduced under an extended variation of the maximum mean discrepancy (MMD) criterion. The novel algorithm - multiple-domain NMF (MDNMF) - was evaluated on two challenging multiple-domain learning problems - multiple user spam email detection and multiple-domain glioma diagnosis. The effectiveness of the proposed algorithm is experimentally verified. © 2013 Elsevier Ltd. All rights reserved.

Cellular Entry of the Diphtheria Toxin Does Not Require the Formation of the Open-Channel State by Its Translocation Domain

Directory of Open Access Journals (Sweden)

Alexey S. Ladokhin

2017-09-01

Full Text Available Cellular entry of diphtheria toxin is a multistage process involving receptor targeting, endocytosis, and translocation of the catalytic domain across the endosomal membrane into the cytosol. The latter is ensured by the translocation (T domain of the toxin, capable of undergoing conformational refolding and membrane insertion in response to the acidification of the endosomal environment. While numerous now classical studies have demonstrated the formation of an ion-conducting conformation—the Open-Channel State (OCS—as the final step of the refolding pathway, it remains unclear whether this channel constitutes an in vivo translocation pathway or is a byproduct of the translocation. To address this question, we measure functional activity of known OCS-blocking mutants with H-to-Q replacements of C-terminal histidines of the T-domain. We also test the ability of these mutants to translocate their own N-terminus across lipid bilayers of model vesicles. The results of both experiments indicate that translocation activity does not correlate with previously published OCS activity. Finally, we determined the topology of TH5 helix in membrane-inserted T-domain using W281 fluorescence and its depth-dependent quenching by brominated lipids. Our results indicate that while TH5 becomes a transbilayer helix in a wild-type protein, it fails to insert in the case of the OCS-blocking mutant H322Q. We conclude that the formation of the OCS is not necessary for the functional translocation by the T-domain, at least in the histidine-replacement mutants, suggesting that the OCS is unlikely to constitute a translocation pathway for the cellular entry of diphtheria toxin in vivo.

Onshore industrial wind turbine locations for the United States up to March 2014

Science.gov (United States)

Diffendorfer, James E.; Kramer, Louisa; Ancona, Zachary H.; Garrity, Christopher P.

2015-01-01

Wind energy is a rapidly growing form of renewable energy in the United States. While summary information on the total amounts of installed capacity are available by state, a free, centralized, national, turbine-level, geospatial dataset useful for scientific research, land and resource management, and other uses did not exist. Available in multiple formats and in a web application, these public domain data provide industrial-scale onshore wind turbine locations in the United States up to March 2014, corresponding facility information, and turbine technical specifications. Wind turbine records have been collected and compiled from various public sources, digitized or position verified from aerial imagery, and quality assured and quality controlled. Technical specifications for turbines were assigned based on the wind turbine make and model as described in public literature. In some cases, turbines were not seen in imagery or turbine information did not exist or was difficult to obtain. Uncertainty associated with these is recorded in a confidence rating.

Onshore industrial wind turbine locations for the United States up to March 2014.

Science.gov (United States)

Diffendorfer, Jay E; Kramer, Louisa A; Ancona, Zach H; Garrity, Christopher P

2015-11-24

Wind energy is a rapidly growing form of renewable energy in the United States. While summary information on the total amounts of installed capacity are available by state, a free, centralized, national, turbine-level, geospatial dataset useful for scientific research, land and resource management, and other uses did not exist. Available in multiple formats and in a web application, these public domain data provide industrial-scale onshore wind turbine locations in the United States up to March 2014, corresponding facility information, and turbine technical specifications. Wind turbine records have been collected and compiled from various public sources, digitized or position verified from aerial imagery, and quality assured and quality controlled. Technical specifications for turbines were assigned based on the wind turbine make and model as described in public literature. In some cases, turbines were not seen in imagery or turbine information did not exist or was difficult to obtain. Uncertainty associated with these is recorded in a confidence rating.

Regular periodical public disclosure obligations of public companies

Directory of Open Access Journals (Sweden)

Marjanski Vladimir

2011-01-01

Full Text Available Public companies in the capacity of capital market participants have the obligation to inform the public on their legal and financial status, their general business operations, as well as on the issuance of securities and other financial instruments. Such obligations may be divided into two groups: The first group consists of regular periodical public disclosures, such as the publication of financial reports (annual, semi-annual and quarterly, and the management's reports on the public company's business operations. The second group comprises the obligation of occasional (ad hoc public disclosure. The thesis analyses the obligation of public companies to inform the public in course of their regular reporting. The new Capital Market Law based on two EU Directives (the Transparency Directive and the Directive on Public Disclosure of Inside Information and the Definition of Market Manipulation regulates such obligation of public companies in substantially more detail than the prior Law on the Market of Securities and Other Financial Instruments (hereinafter: ZTHV. Due to the above the ZTHV's provisions are compared to the new solutions within the domain of regular periodical disclosure of the Capital Market Law.

Incentive regulation of nuclear power plants by state public utility commissions

International Nuclear Information System (INIS)

Petersen, J.C.

1987-12-01

This report on incentive regulation of nuclear power plants by state public utility commissions (PUCs). Economic performance incentives established by state PUCs are applicable to the construction or operation of about 45 nuclear power reactors owned by 30 utilities in 17 states. The NRC staff monitors development of the incentives and periodically provides an updated report on all nuclear plant incentives to its regional offices. The staff maintains contact with the PUCs and the utilities responsible for implementing the incentives in order to obtain the updated information and to consider potential safety effects of the incentives. This report presents the NRC staff's concerns on potential safety effects of economic performance incentives. It also includes a plant-by-plant survey that describes the mechanics of each incentive and discusses the financial effects of the incentive on the utility-owner(s) of the plant

The High Cost of Failing to Reform Public Education in Indiana. School Choice Issues in the State

Science.gov (United States)

Gottlob, Brian J.

2006-01-01

This study documents the public costs of high school dropouts in Indiana, and examines how school choice would provide large public benefits by increasing the graduation rate in Indiana public schools. It calculates the annual cost of high school dropouts in Indiana due to lower state income tax payments, increased reliance on Medicaid, and…

State Public Policies and the Racial/Ethnic Stratification of College Access and Choice in the State of Maryland

Science.gov (United States)

Perna, Laura W.; Steele, Patricia; Woda, Susan; Hibbert, Taifa

2005-01-01

This study uses descriptive analyses of data from multiple sources to examine changes during the 1990s in the racial/ethnic stratification of college access and choice in Maryland and to explore state public policies that may have influenced changes in the demand for and supply of higher education for students of different racial/ethnic groups…

Insights into signal transduction by a hybrid FixL: Denaturation study of on and off states of a multi-domain oxygen sensor.

Science.gov (United States)

Guimarães, Wellinson G; Gondim, Ana C S; Costa, Pedro Mikael da Silva; Gilles-Gonzalez, Marie-Alda; Lopes, Luiz G F; Carepo, Marta S P; Sousa, Eduardo H S

2017-07-01

FixL from Rhizobium etli (ReFixL) is a hybrid oxygen sensor protein. Signal transduction in ReFixL is effected by a switch off of the kinase activity on binding of an oxygen molecule to ferrous heme iron in another domain. Cyanide can also inhibit the kinase activity upon binding to the heme iron in the ferric state. The unfolding by urea of the purified full-length ReFixL in both active pentacoordinate form, met-FixL(Fe III ) and inactive cyanomet-FixL (Fe III -CN - ) form was monitored by UV-visible absorption spectroscopy, circular dichroism (CD) and fluorescence spectroscopy. The CD and UV-visible absorption spectroscopy revealed two states during unfolding, whereas fluorescence spectroscopy identified a three-state unfolding mechanism. The unfolding mechanism was not altered for the active compared to the inactive state; however, differences in the ΔG H2O were observed. According to the CD results, compared to cyanomet-FixL, met-FixL was more stable towards chemical denaturation by urea (7.2 vs 4.8kJmol -1 ). By contrast, electronic spectroscopy monitoring of the Soret band showed cyanomet-FixL to be more stable than met-FixL (18.5 versus 36.2kJmol -1 ). For the three-state mechanism exhibited by fluorescence, the ΔG H2O for both denaturation steps were higher for the active-state met-FixL than for cyanomet-FixL. The overall stability of met-FixL is higher in comparison to cyanomet-FixL suggesting a more compact protein in the active form. Nonetheless, hydrogen bonding by bound cyanide in the inactive state promotes the stability of the heme domain. This work supports a model of signal transduction by FixL that is likely shared by other heme-based sensors. Copyright © 2017 Elsevier Inc. All rights reserved.

Public attitudes toward biofuels. Effects of knowledge, political partisanship, and media use.

Science.gov (United States)

Cacciatore, Michael A; Binder, Andrew R; Scheufele, Dietram A; Shaw, Bret R

2012-01-01

Despite large-scale investments and government mandates to expand biofuels development and infrastructure in the United States, little is known about how the public conceives of this alternative fuel technology. This study examines public opinion of biofuels by focusing on citizen knowledge and the motivated processing of media information. Specifically, we explore the direct effects of biofuels knowledge and the moderating effect of partisanship on the relationship between media use and benefit vs. risk perceptions in the following four domains: environmental impacts, economic consequences, ethical/social implications, and political ramifications. Our results suggest that more knowledgeable respondents see fewer benefits of biofuels relative to risks, and that Democrats and Republicans are affected differently by media use when forming opinions about biofuels. Among Democrats, greater attention to political media content leads to a more favorable outlook toward the technology across several domains of interest, while among Republicans, an increase in attention to political content has the opposite effect. Possible reasons for these results, as well as implications of the findings at the intersection of politics and the life sciences, are discussed.

THE ROLE OF THE STATE IN ADAM SMITH’S THOUGHT SYSTEM AND MODERN PUBLIC FINANCE THEORY: A COMPARATIVE EVALUATION

Directory of Open Access Journals (Sweden)

Turan YAY

2010-07-01

Full Text Available What are the main functions of the state? Which functions must be fulfilled by the state, which functions must be not? How should the state fulfill these responsibilities? What must be the main principles of the state, related to public expenditures, taxation and debt policies? In this paper, the place of the role and functions of the state in Adam Smith’s thought system will be discussed. In this context, especially the related parts of the Wealth of Nations and Lectures on Jurisprudence will be focused on and evaluated in the light of contemporary public finance theory

CDC’s National Environmental Public Health Tracking Program in Action: Case Studies From State and Local Health Departments

Science.gov (United States)

Eatman, Shana; Strosnider, Heather M.

2017-01-01

The Centers for Disease Control and Prevention’s (CDC’s) National Environmental Public Health Tracking Program (Tracking Program) is a multidisciplinary collaboration that involves the ongoing collection, integration, analysis, interpretation, and dissemination of data from environmental hazard monitoring, human exposure surveillance, and health effects surveillance. With a renewed focus on data-driven decision-making, the CDC’s Tracking Program emphasizes dissemination of actionable data to public health practitioners, policy makers, and communities. The CDC’s National Environmental Public Health Tracking Network (Tracking Network), a Web-based system with components at the national, state, and local levels, houses environmental public health data used to inform public health actions (PHAs) to improve community health. This article serves as a detailed landscape on the Tracking Program and Tracking Network and the Tracking Program’s leading performance measure, “public health actions.” Tracking PHAs are qualitative statements addressing a local problem or situation, the role of the state or local Tracking Program, how the problem or situation was addressed, and the action taken. More than 400 PHAs have been reported by funded state and local health departments since the Tracking Program began collecting PHAs in 2005. Three case studies are provided to illustrate the use of the Tracking Program resources and data on the Tracking Network, and the diversity of actions taken. Through a collaborative network of experts, data, and tools, the Tracking Program and its Tracking Network are actively informing state and local PHAs. In a time of competing priorities and limited funding, PHAs can serve as a powerful tool to advance environmental public health practice. PMID:28763381

Public health and allied career choices for AYUSH graduates in India

Directory of Open Access Journals (Sweden)

Janmejaya Samal

2013-01-01

Full Text Available Introduction Until the very recent time majority of AYUSH graduates were limited to their own field of study with few exceptions in to the field of public health and allied areas. The reasons could be lack of awareness, unavailability of suitable job opportunity or a sense of insecurity in a relatively new and offbeat domain of work. However more recently, there has been a paradigm shift; with increase in information access, awareness of job opportunities and a great degree of professional and personal satisfaction. This has led to a huge rush of these graduates in to the field of public health and allied areas. Objective ToexplorepublichealthandalliedcareerchoicesforAYUSHgraduateswithspecialreferencetothe scopes and opportunities in each of these fields. Methodology Review based study. Information was obtained by systematic search process using internet based Google, Google Scholar search engines. Discussion The results obtained were pertinent to the domain of public health and allied careers including Public health and related areas such as; Health and Hospital Management, Health Policy, Health Economics, Heath Care Financing, Epidemiology, Medical Sociology, Clinical Research, Pharmaceutical Management etc. it is observed that the placement and job opportunities are much more because of the rapid expansion of health care industry in India with endeavors from public and private stakeholders. There has been a multimillion dollars investment by various national and international donor agencies, pharmaceutical sector, central and state governments and the development partners. Conclusion AYUSH graduates can definitely find this field interesting as well as challenging and job opportunities may not be a problem for the right one.

Public Parks and Wellbeing in Urban Areas of the United States.

Directory of Open Access Journals (Sweden)

Lincoln R Larson

Full Text Available Sustainable development efforts in urban areas often focus on understanding and managing factors that influence all aspects of health and wellbeing. Research has shown that public parks and green space provide a variety of physical, psychological, and social benefits to urban residents, but few studies have examined the influence of parks on comprehensive measures of subjective wellbeing at the city level. Using 2014 data from 44 U.S. cities, we evaluated the relationship between urban park quantity, quality, and accessibility and aggregate self-reported scores on the Gallup-Healthways Wellbeing Index (WBI, which considers five different domains of wellbeing (e.g., physical, community, social, financial, and purpose. In addition to park-related variables, our best-fitting OLS regression models selected using an information theory approach controlled for a variety of other typical geographic and socio-demographic correlates of wellbeing. Park quantity (measured as the percentage of city area covered by public parks was among the strongest predictors of overall wellbeing, and the strength of this relationship appeared to be driven by parks' contributions to physical and community wellbeing. Park quality (measured as per capita spending on parks and accessibility (measured as the overall percentage of a city's population within ½ mile of parks were also positively associated with wellbeing, though these relationships were not significant. Results suggest that expansive park networks are linked to multiple aspects of health and wellbeing in cities and positively impact urban quality of life.

Communication self-assessment by public prosecutors in a north-eastern Brazilian state.

Science.gov (United States)

Sales, Neuza Josina; Castaneda, Daniel Francisco Neyra; Barreto, Íkaro Daniel de Carvalho; Paoliello, Marina; Campanha, Silvia Márcia Andrade

2016-01-01

To describe how public prosecutors self-assess their communication approaches and how listeners react to them; to analyze how this relates to gender, age, and work experience. Descriptive, transversal study. A questionnaire was developed and sent to 126 public prosecutors for completion. Thirty-three completed questionnaires were sent back. The independent variables were gender, age, and number of years of professional experience. The dependent variables were communication self-assessment throughout the years of work, communication parameters used, and listeners' reactions. A descriptive analyzis and Fisher's Exact Test was carried out. the sample contained both male and female participants with a median age of 43 years and an average of 20 years of professional experience. Most of the respondents claimed they had experienced demotivation, insecurity, tension, and difficulty when trying to convince listeners. More women than men reported they felt that their communication had worsened throughout their careers. All the women reported they experienced insecurity when speaking in public. One third of the public prosecutors stated they suffered from disorders on their voice. Those respondents aged over 43, experienced greater proportion on voice change than younger ones. In contrast to their younger colleagues, the majority of public prosecutors with more than 20 years of professional experience revealed that they felt insecure when speaking in public. the public prosecutors identified their strong and weak communication parameters. Gender, age, and work experience affect communicative performance.

Effect of increasing disorder on domains of the 2d Coulomb glass.

Science.gov (United States)

Bhandari, Preeti; Malik, Vikas

2017-12-06

We have studied a two dimensional lattice model of Coulomb glass for a wide range of disorders at [Formula: see text]. The system was first annealed using Monte Carlo simulation. Further minimization of the total energy of the system was done using an algorithm developed by Baranovskii et al, followed by cluster flipping to obtain the pseudo-ground states. We have shown that the energy required to create a domain of linear size L in d dimensions is proportional to [Formula: see text]. Using Imry-Ma arguments given for random field Ising model, one gets critical dimension [Formula: see text] for Coulomb glass. The investigation of domains in the transition region shows a discontinuity in staggered magnetization which is an indication of a first-order type transition from charge-ordered phase to disordered phase. The structure and nature of random field fluctuations of the second largest domain in Coulomb glass are inconsistent with the assumptions of Imry and Ma, as was also reported for random field Ising model. The study of domains showed that in the transition region there were mostly two large domains, and that as disorder was increased the two large domains remained, but a large number of small domains also opened up. We have also studied the properties of the second largest domain as a function of disorder. We furthermore analysed the effect of disorder on the density of states, and showed a transition from hard gap at low disorders to a soft gap at higher disorders. At [Formula: see text], we have analysed the soft gap in detail, and found that the density of states deviates slightly ([Formula: see text]) from the linear behaviour in two dimensions. Analysis of local minima show that the pseudo-ground states have similar structure.

Institutionalizing the Human Domain: Achieving Cross Domain Synergy for Every Day Missions

Science.gov (United States)

2017-04-06

others rely on more primitive and traditional sources of information or are characterized by strong central government censorship . Technology can play...many societies, others rely on more primitive and traditional sources of information or are characterized by strong central government censorship and...Capabilities for Operations in the Human Domain 92 31 Notes 1 The National Military Strategy of the United States of America , 2015

Absorption and fluorescence spectroscopic characterization of BLUF domain of AppA from Rhodobacter sphaeroides

Science.gov (United States)

Zirak, P.; Penzkofer, A.; Schiereis, T.; Hegemann, P.; Jung, A.; Schlichting, I.

2005-08-01

The BLUF domain of the transcriptional anti-repressor protein AppA from the non-sulfur anoxyphototrophic purple bacterium Rhodobacter sphaeroides was characterized by absorption and emission spectroscopy. The BLUF domain constructs AppA 148 (consisting of amino-acid residues 1-148) and AppA 126 (amino-acid residues 1-126) are investigated. The cofactor of the investigated domains is found to consist of a mixture of the flavins riboflavin, FMN, and FAD. The dark-adapted domains exist in two different active receptor conformations (receptor states) with different sub-nanosecond fluorescence lifetimes (BLUF r,f and BLUF r,sl) and a small non-interacting conformation (BLUF nc). The active receptor conformations are transformed to putative signalling states (BLUF s,f and BLUF s,sl) of low fluorescence efficiency and picosecond fluorescence lifetime by blue-light excitation (light-adapted domains). In the dark at room temperature both signalling states recover back to the initial receptor states with a time constant of about 17 min. A quantum yield of signalling state formation of about 25% was determined by intensity dependent transmission measurements. A photo-cycle scheme is presented including photo-induced charge transfer complex formation, charge recombination, and protein binding pocket reorganisation.

Absorption and fluorescence spectroscopic characterization of BLUF domain of AppA from Rhodobacter sphaeroides

International Nuclear Information System (INIS)

Zirak, P.; Penzkofer, A.; Schiereis, T.; Hegemann, P.; Jung, A.; Schlichting, I.

2005-01-01

The BLUF domain of the transcriptional anti-repressor protein AppA from the non-sulfur anoxyphototrophic purple bacterium Rhodobacter sphaeroides was characterized by absorption and emission spectroscopy. The BLUF domain constructs AppA 148 (consisting of amino-acid residues 1-148) and AppA 126 (amino-acid residues 1-126) are investigated. The cofactor of the investigated domains is found to consist of a mixture of the flavins riboflavin, FMN, and FAD. The dark-adapted domains exist in two different active receptor conformations (receptor states) with different sub-nanosecond fluorescence lifetimes (BLUF r,f and BLUF r,sl ) and a small non-interacting conformation (BLUF nc ). The active receptor conformations are transformed to putative signalling states (BLUF s,f and BLUF s,sl ) of low fluorescence efficiency and picosecond fluorescence lifetime by blue-light excitation (light-adapted domains). In the dark at room temperature both signalling states recover back to the initial receptor states with a time constant of about 17 min. A quantum yield of signalling state formation of about 25% was determined by intensity dependent transmission measurements. A photo-cycle scheme is presented including photo-induced charge transfer complex formation, charge recombination, and protein binding pocket reorganisation

Public Governance and Governability: Accountability and Disclosure permitted by Accounting Applied to the Public Sector as a Sustainability Instrument for the State

OpenAIRE

Antonio Gonçalves Oliveira; Hilda Alberton Carvalho; Dayanne Paretti Corrêa

2013-01-01

In an accounting-financial perspective applied to business organizations, the Going-Concern Principle presupposes their sustainability towards perpetuity, influencing and guaranteeing investors’ returns. In Public Management, this is no different, underlining the existence of the Going-Concern Principle of the State. This describes the State as a political society that, like the company, should be perennial and sustainable, always aiming for the promotion of the common good and the developmen...

Conformational stability analyses of alpha subunit I domain of LFA-1 and Mac-1.

Directory of Open Access Journals (Sweden)

Debin Mao

Full Text Available β₂ integrin of lymphocyte function-associated antigen-1 (LFA-1 or macrophage-1 antigen (Mac-1 binds to their common ligand of intercellular adhesion molecule-1 (ICAM-1 and mediates leukocyte-endothelial cell (EC adhesions in inflammation cascade. Although the two integrins are known to have distinct functions, the corresponding micro-structural bases remain unclear. Here (steered-molecular dynamics simulations were employed to elucidate the conformational stability of α subunit I domains of LFA-1 and Mac-1 in different affinity states and relevant I domain-ICAM-1 interaction features. Compared with low affinity (LA Mac-1, the LA LFA-1 I domain was unstable in the presence or absence of ICAM-1 ligand, stemming from diverse orientations of its α₇-helix with different motifs of zipper-like hydrophobic junction between α₁- and α₇-helices. Meanwhile, spontaneous transition of LFA-1 I domain from LA state to intermediate affinity (IA state was first visualized. All the LA, IA, and high affinity (HA states of LFA-1 I domain and HA Mac-1 I domain were able to bind to ICAM-1 ligand effectively, while LA Mac-1 I domain was unfavorable for binding ligand presumably due to the specific orientation of S144 side-chain that capped the MIDAS ion. These results furthered our understanding in correlating the structural bases with their functions of LFA-1 and Mac-1 integrins from the viewpoint of I domain conformational stability and of the characteristics of I domain-ICAM-1 interactions.

Cardiopulmonary resuscitation training in Washington state public high schools.

Science.gov (United States)

Reder, Sheri; Quan, Linda

2003-03-01

To determine the best approaches for increasing cardiopulmonary resuscitation (CPR) training opportunities for public high school students, we conducted a statewide survey of all 310 public high schools in Washington State. The findings describe CPR student training currently provided by high schools, barriers to providing, and strategies to increase CPR training of high school students. The response rate was 89% (276 schools) from a combination of mail and telephone surveys; 35% (n=97) reported that they did not provide any CPR student training. Of the 132 schools that provided CPR student training, 23% trained less than 10% of their students, and 39% trained more than 90% of their students. The majority of public high schools, 70%, did not have any teacher trained to teach CPR or had only one teacher with such training. Yet 80% of schools felt that CPR training is best provided in school settings. Schools perceived the greatest benefit of CPR training as providing students with the skill to save a life (43%). The most frequently identified barriers were logistical: limited time to teach the curriculum (24%), lack of funds (16%), and instructor scheduling difficulties (17%). Less than 5% of respondents voiced any opposition to CPR training, and that opposition was for logistical reasons. To increase CPR training, the single best strategies suggested were: increase funding, provide time in the curriculum, have more certified instructors, and make CPR student training a requirement.

Health domains for sale: the need for global health Internet governance.

Science.gov (United States)

Mackey, Tim Ken; Liang, Bryan A; Kohler, Jillian C; Attaran, Amir

2014-03-05

A debate on Internet governance for health, or "eHealth governance", is emerging with the impending award of a new dot-health (.health) generic top-level domain name (gTLD) along with a host of other health-related domains. This development is critical as it will shape the future of the health Internet, allowing largely unrestricted use of .health second-level domain names by future registrants, raising concerns about the potential for privacy, use and marketing of health-related information, credibility of online health content, and potential for Internet fraud and abuse. Yet, prospective .health gTLD applicants do not provide adequate safeguards for use of .health or related domains and have few or no ties to the global health community. If approved, one of these for-profit corporate applicants would effectively control the future of the .health address on the Internet with arguably no active oversight from important international public health stakeholders. This would represent a lost opportunity for the public health, medical, and broader health community in establishing a trusted, transparent and reliable source for health on the Internet. Countries, medical associations, civil society, and consumer advocates have objected to these applications on grounds that they do not meet the public interest. We argue that there is an immediate need for action to postpone awarding of the .health gTLD and other health-related gTLDs to address these concerns and ensure the appropriate development of sound eHealth governance rules, principles, and use. This would support the crucial need of ensuring access to quality and evidence-based sources of health information online, as well as establishing a safe and reliable space on the Internet for health. We believe, if properly governed, .health and other domains could represent such a promise in the future.

Spatial Domain Adaptive Control of Nonlinear Rotary Systems Subject to Spatially Periodic Disturbances

Directory of Open Access Journals (Sweden)

Yen-Hsiu Yang

2012-01-01

Full Text Available We propose a generic spatial domain control scheme for a class of nonlinear rotary systems of variable speeds and subject to spatially periodic disturbances. The nonlinear model of the rotary system in time domain is transformed into one in spatial domain employing a coordinate transformation with respect to angular displacement. Under the circumstances that measurement of the system states is not available, a nonlinear state observer is established for providing the estimated states. A two-degree-of-freedom spatial domain control configuration is then proposed to stabilize the system and improve the tracking performance. The first control module applies adaptive backstepping with projected parametric update and concentrates on robust stabilization of the closed-loop system. The second control module introduces an internal model of the periodic disturbances cascaded with a loop-shaping filter, which not only further reduces the tracking error but also improves parametric adaptation. The overall spatial domain output feedback adaptive control system is robust to model uncertainties and state estimated error and capable of rejecting spatially periodic disturbances under varying system speeds. Stability proof of the overall system is given. A design example with simulation demonstrates the applicability of the proposed design.

[Domains of physical activity in slave-descendant communities in Southwest Bahia State, Brazil: a population-based study].

Science.gov (United States)

Bezerra, Vanessa Moraes; Andrade, Amanda Cristina de Souza; César, Cibele Comini; Caiaffa, Waleska Teixeira

2015-06-01

This study aimed to describe the prevalence of physical activity (PA) and associated factors in various domains (leisure-time, work, home, and commuting) among quilombolas (descendants of African slaves) in Bahia State, Brazil. This was a cross-sectional study of 797 individuals from 18 to 100 years of age. The study adopted a cutoff point of 150 minutes of PA per week. A hierarchical Poisson model was used. The highest prevalence of PA was at work (42.1%), followed by the home environment (39.3%), commuting (35.5%), and leisure time (13.1%). PA at work was associated with male gender, lower age, higher schooling, and consumption of alcohol and fruits. PA in the household domain was associated with female gender, lower age, marital status (married), and negative self-rated health. In commuting, PA was associated with male gender and lower age bracket, and during leisure time with safety, male gender, lower age, and higher schooling. The study concludes that this slave-descendant community displays a profile of PA that is characteristic of rural groups (more active at work, with little leisure-time activity). The determinants of PA were similar to those seen in urban groups.

Resolving the Origin of Pseudo-Single Domain Magnetic Behavior

Science.gov (United States)

Roberts, Andrew P.; Almeida, Trevor P.; Church, Nathan S.; Harrison, Richard J.; Heslop, David; Li, Yiliang; Li, Jinhua; Muxworthy, Adrian R.; Williams, Wyn; Zhao, Xiang

2017-12-01

The term "pseudo-single domain" (PSD) has been used to describe the transitional state in rock magnetism that spans the particle size range between the single domain (SD) and multidomain (MD) states. The particle size range for the stable SD state in the most commonly occurring terrestrial magnetic mineral, magnetite, is so narrow ( 20-75 nm) that it is widely considered that much of the paleomagnetic record of interest is carried by PSD rather than stable SD particles. The PSD concept has, thus, become the dominant explanation for the magnetization associated with a major fraction of particles that record paleomagnetic signals throughout geological time. In this paper, we argue that in contrast to the SD and MD states, the term PSD does not describe the relevant physical processes, which have been documented extensively using three-dimensional micromagnetic modeling and by parallel research in material science and solid-state physics. We also argue that features attributed to PSD behavior can be explained by nucleation of a single magnetic vortex immediately above the maximum stable SD transition size. With increasing particle size, multiple vortices, antivortices, and domain walls can nucleate, which produce variable cancellation of magnetic moments and a gradual transition into the MD state. Thus, while the term PSD describes a well-known transitional state, it fails to describe adequately the physics of the relevant processes. We recommend that use of this term should be discontinued in favor of "vortex state," which spans a range of behaviors associated with magnetic vortices.

Field-induced strain memory with non-180 .deg. domain-reorientation control

International Nuclear Information System (INIS)

Kadota, Yoichi; Hosaka, Hiroshi; Morita, Takeshi

2010-01-01

Using non-180 .deg. domain-reorientation control, we propose the strain memory effect in ferroelectric ceramics. Electric fields with asymmetric amplitudes were applied to soft-type lead zirconate titanate (PZT) ceramics, and the strain hysteresis and the polarization loop were measured. The butterfly curve became asymmetric under an electric field with a particular asymmetric amplitude. The asymmetric butterfly curve had two stable strain states at zero electric field. Thus, the strain memory effect was realized as the difference between the two stable strain states. An XRD analysis was carried out to verify the contribution of the non-180 .deg. domain reorientation to the strain memory effect. The non-180 .deg. domain reorientation was determined as the intensity ratio of the (002) to the (200) peak. The strain memory determined from macroscopic strain measurements had a linear relationship to the non-180 .deg. domain volume fraction. This result indicated the origin of the strain memory to be the non-180 .deg. domain reorientation.

Certification of Public Librarians in the United States. A Detailed Summary of Legally Mandated and Voluntary Certification Plans for Public Librarians Based on Information Supplied by the Various Certificating State Agencies or Other Appropriate Sources. 3rd Edition.

Science.gov (United States)

Coe, Mary J., Ed.

This report contains summaries of legally mandated and voluntary certification plans for public librarians in the United States based on information supplied by the various certifying state agencies or other appropriate sources in April 1979. Each plan is identified by the descriptive terms "mandatory" (certification required by law--23 states),…

77 FR 56674 - United States v. Humana Inc. and Arcadian Management Services, Inc.; Public Comment and Response...

Science.gov (United States)

2012-09-13

... students in the United States. The AMA's comment states that: MA [Medicare Advantage] plans in competitive... Services, Inc.; Public Comment and Response on Proposed Final Judgment Pursuant to the Antitrust Procedures... on the proposed Final Judgment in United States v. Humana Inc. and Arcadian Management Services, Inc...

Incentive regulation of nuclear power plants by state Public Utility Commissions

International Nuclear Information System (INIS)

Martin, R.L.; Olson, J.; Hendrickson, P.

1989-12-01

Economic performance incentives established by state Public Utility Commissions (PUCs) currently are applicable to the construction or operation of approximately 73 nuclear power reactors owned by 27 utilities with investment greater than 10% in 18 states. The NRC staff monitors development of the incentives and periodically provides an updated report on all nuclear plant incentives to its headquarters and regional offices. The staff maintains contact with the PUCs and the utilities responsible for implementing the incentives in order to obtain the updated information and to consider potential safety effects of the incentives. This report on incentive regulation of nuclear power plants by state PUCs presents the NRC staff's concerns on potential safety effects of economic performance incentives. It also includes a plant-by-plant survey that describes the mechanics of each incentive and discusses the financial effects of the incentive on the utility-owner(s) of the plant

Domains and domain loss

DEFF Research Database (Denmark)

Haberland, Hartmut

2005-01-01

politicians and in the media, especially in the discussion whether some languages undergo ‘domain loss’ vis-à-vis powerful international languages like English. An objection that has been raised here is that domains, as originally conceived, are parameters of language choice and not properties of languages...

Integrational Models and Forms of Inter-State Public-Private Partnership: Aspects of Financial Convergence

Directory of Open Access Journals (Sweden)

ALINA KULAI

2015-10-01

Full Text Available In the article we examined the main models and forms of public-private partnership, their role in the socio-economic development and deepening of financial convergence of countries-participants of the partnership. The attention was paid to decentralization of inter-state forms of public-private partnership as the basis of cross-border and transnational partnership. The scientific research, described in this publication, have found their practical application in the realization of the project within Euro-region “Bug”. This project has founded a joined Ukrainian – Polish institution of labor migration administration and also of granting necessary permissions for realization activities within Ukraine.

Improving the performance of DomainDiscovery of protein domain boundary assignment using inter-domain linker index

Directory of Open Access Journals (Sweden)

Zomaya Albert Y

2006-12-01

Full Text Available Abstract Background Knowledge of protein domain boundaries is critical for the characterisation and understanding of protein function. The ability to identify domains without the knowledge of the structure – by using sequence information only – is an essential step in many types of protein analyses. In this present study, we demonstrate that the performance of DomainDiscovery is improved significantly by including the inter-domain linker index value for domain identification from sequence-based information. Improved DomainDiscovery uses a Support Vector Machine (SVM approach and a unique training dataset built on the principle of consensus among experts in defining domains in protein structure. The SVM was trained using a PSSM (Position Specific Scoring Matrix, secondary structure, solvent accessibility information and inter-domain linker index to detect possible domain boundaries for a target sequence. Results Improved DomainDiscovery is compared with other methods by benchmarking against a structurally non-redundant dataset and also CASP5 targets. Improved DomainDiscovery achieves 70% accuracy for domain boundary identification in multi-domains proteins. Conclusion Improved DomainDiscovery compares favourably to the performance of other methods and excels in the identification of domain boundaries for multi-domain proteins as a result of introducing support vector machine with benchmark_2 dataset.

Conformational analysis of isolated domains of Helicobacter pylori CagA.

Directory of Open Access Journals (Sweden)

Amanda P Woon

Full Text Available The CagA protein of Helicobacter pylori is associated with increased virulence and gastric cancer risk. CagA is translocated into the host cell by a H. pylori type IV secretion system via mechanisms that are poorly understood. Translocated CagA interacts with numerous host factors, altering a variety of host signalling pathways. The recently determined crystal structure of C-terminally-truncated CagA indicated the presence of two domains: the smaller, flexible N-terminal domain and the larger, middle domain. In this study, we have investigated the conformation, oligomeric state and stability of the N-terminal, middle and glutamate-proline-isoleucine-tyrosine-alanine (EPIYA-repeats domains. All three domains are monomeric, suggesting that the multimerisation of CagA observed in infected cells is likely to be mediated not by CagA itself but by its interacting partners. The middle and the C-terminal domains, but not the N-terminal domain, are capable of refolding spontaneously upon heat denaturation, lending support to the hypothesis that unfolded CagA is threaded C-terminus first through the type IV secretion channel with its N-terminal domain, which likely requires interactions with other domains to refold, being threaded last. Our findings also revealed that the C-terminal EPIYA-repeats domain of CagA exists in an intrinsically disordered premolten globule state with regions in PPII conformation--a feature that is shared by many scaffold proteins that bind multiple protein components of signalling pathways. Taken together, these results provide a deeper understanding of the physicochemical properties of CagA that underpin its complex cellular and oncogenic functions.

The role of the State Audit Institution in prevention of white-collar crime in the public sector

Directory of Open Access Journals (Sweden)

Šuput Jelena

2014-01-01

Full Text Available In this paper, the author points out to the important role of the Serbian State Audit Institution in prevention of corruptive practices, felonies and white-collar crime in the public sector in the Republic of Serbia. Although the activity of supreme state auditors is not primarily aimed at detecting criminal offences in the public sector, their efforts and results in this area are by no means insignificant. This is due to the fact that state auditors are well-trained to interpret and apply the legal provisions from the area of public finance, public procurements and accountancy, regulating the budget system of revenues and expenditures whose violation may constitute a criminal offence within the scope of white-collar crime. Considering the fact that it is an independent and autonomous state authority, the Serbian Supreme Audit Institution should play a very important role in reducing 'the dark figures of white-collar crime'. In many cases, the fear of crime detection as well as the fear of being punished are sufficient to exert the preventive effect on the potential perpetrators of white-collar crimes. However, we have to bear in mind that the prevention of corruption and other felonies which are qualified as white-collar crime calls for a joint effort of all state institutions and citizens alike. Another fact which is very important for improving the operative quality of the Supreme Audit Institution is its membership in the International Organisation of Supreme Audit Institutions and cooperation with the Supreme Audit Institutions in other countries.

Valuation of scleroderma and psoriatic arthritis health states by the general public

Directory of Open Access Journals (Sweden)

Hays Ron D

2010-10-01

Full Text Available Abstract Objective Psoriatic arthritis (PsA and scleroderma (SSc are chronic rheumatic disorders with detrimental effects on health-related quality of life. Our objective was to assess health values (utilities from the general public for health states common to people with PsA and SSc for economic evaluations. Methods Adult subjects from the general population in a Midwestern city (N = 218 completed the SF-12 Health Survey and computer-assisted 0-100 rating scale (RS, time trade-off (TTO, range: 0.0-1.0 and standard gamble (SG, range: 0.0-1.0 utility assessments for several hypothetical PsA and SSc health states. Results Subjects included 135 (62% females, 143 (66% Caucasians, and 62 (28% African-Americans. The mean (SD scores for the SF-12 Physical Component Summary scale were 52.9 (8.3 and for the SF-12 Mental Component Summary scale were 49.0 (9.1, close to population norms. The mean RS, TTO, and SG scores for PsA health states varied with severity, ranging from 20.2 to 63.7 (14.4-20.3 for the RS 0.29 to 0.78 (0.24-0.31 for the TTO, and 0.48 to 0.82 (0.24-0.34 for the SG. The mean RS, TTO, and SG scores for SSc health states were 25.3-69.7 (15.2-16.3 for the RS, 0.36-0.80 (0.25-0.31 for the TTO, and 0.50-0.81 (0.26-0.32 for the SG, depending on disease severity. Conclusion Health utilities for PsA and SSc health states as assessed from the general public reflect the severity of the diseases. These descriptive findings could have implications regarding comparative effectiveness research for tests and treatments for PsA and SSc.

Columbia Public Health Core Curriculum: Short-Term Impact.

Science.gov (United States)

Begg, Melissa D; Fried, Linda P; Glover, Jim W; Delva, Marlyn; Wiggin, Maggie; Hooper, Leah; Saxena, Roheeni; de Pinho, Helen; Slomin, Emily; Walker, Julia R; Galea, Sandro

2015-12-01

We evaluated a transformed core curriculum for the Columbia University, Mailman School of Public Health (New York, New York) master of public health (MPH) degree. The curriculum, launched in 2012, aims to teach public health as it is practiced: in interdisciplinary teams, drawing on expertise from multiple domains to address complex health challenges. We collected evaluation data starting when the first class of students entered the program and ending with their graduation in May 2014. Students reported being very satisfied with and challenged by the rigorous curriculum and felt prepared to integrate concepts across varied domains and disciplines to solve public health problems. This novel interdisciplinary program could serve as a prototype for other schools that wish to reinvigorate MPH training.

Crystal shapes on striped surface domains

International Nuclear Information System (INIS)

Valencia, Antoni

2004-01-01

The equilibrium shapes of a simple cubic crystal in contact with a planar chemically patterned substrate are studied theoretically using an effective interface model. The substrate is primarily made of lyophobic material and is patterned with a lyophilic (easily wettable) stripe domain. Three regimes can be distinguished for the equilibrium shapes of the crystal. The transitions between these regimes as the volume of the crystal is changed are continuous or discontinuous depending on the strength of the couplings between the crystal and the lyophilic and lyophobic surface domains. If the crystal grows through a series of states close to equilibrium, the discontinuous transitions correspond to growth instabilities. These transitions are compared with similar results that have been obtained for a volume of liquid wetting a lyophilic stripe domain

Common Core State Standards in the Middle Grades: What's New in the Geometry Domain and How Can Teachers Support Student Learning?

Science.gov (United States)

Teuscher, Dawn; Tran, Dung; Reys, Barbara J.

2015-01-01

The Common Core State Standards for Mathematics (CCSSM) is a primary focus of attention for many stakeholders' (e.g., teachers, district mathematics leaders, and curriculum developers) intent on improving mathematics education. This article reports on specific content shifts related to the geometry domain in the middle grades (6-8)…

The Concept of Public Goods, the State, and Higher Education Finance: A View from the BRICs

Science.gov (United States)

Carnoy, Martin; Froumin, Isak; Loyalka, Prashant K.; Tilak, Jandhyala B.

2014-01-01

Because higher education serves both public and private interests, the way it is conceived and financed is contested politically, appearing in different forms in different societies. What is public and private in education is a political--social construct, subject to various political forces, primarily interpreted through the prism of the state.…

2017 Emerging Technology Domains Risk Survey

Science.gov (United States)

2017-10-01

REV-03.18.2016.0 2017 Emerging Technology Domains Risk Survey Daniel Klinedinst Joel Land Kyle O’Meara October 2017 TECHNICAL REPORT CMU/SEI...Distribution Statement A: Approved for Public Release. Distribution is Unlimited. List of Tables Table 1: New and Emerging Technologies 2 Table 2: Security...Impact of New and Emerging Technologies 4 Table 3: Severity Classifications and Impact Scores 5 CMU/SEI-2017-TR-008 | SOFTWARE ENGINEERING

2016 Emerging Technology Domains Risk Survey

Science.gov (United States)

2016-04-05

measures upon which the CERT/CC based its recommendations and how each domain was triaged for importance. 6. Exploitation Examples details concepts or...Distribution Statement A: Approved for Public Release; Distribution is Unlimited 2 Methodology A measured approach to analysis is required when...only a few vehicles had access to a cellular Internet connection, and only at 3G speeds. Some vehicles already have LTE connections, and many

Dressed Domain Walls and holography

International Nuclear Information System (INIS)

Grisa, Luca; Pujolas, Oriol

2008-01-01

The cutoff version of the AdS/CFT correspondence states that the Randall Sundrum scenario is dual to a Conformal Field Theory (CFT) coupled to gravity in four dimensions. The gravitational field produced by relativistic Domain Walls can be exactly solved in both sides of the correspondence, and thus provides one further check of it. We show in the two sides that for the most symmetric case, the wall motion does not lead to particle production of the CFT fields. Still, there are nontrivial effects. Due to the trace anomaly, the CFT effectively renormalizes the Domain Wall tension. On the five dimensional side, the wall is a codimension 2 brane localized on the Randall-Sundrum brane, which pulls the wall in a uniform acceleration. This is perceived from the brane as a Domain Wall with a tension slightly larger than its bare value. In both cases, the deviation from General Relativity appears at nonlinear level in the source, and the leading corrections match to the numerical factors.

Metastable states in magnetic nanorings

DEFF Research Database (Denmark)

Castaño, F. J.; Ross, C. A.; Frandsen, Cathrine

2003-01-01

Magnetization states and hysteresis behavior of small ferromagnetic rings, of diameters 180-520 nm, have been investigated using magnetic force microscopy. In addition to the expected bi-domain ("onion") and flux-closed ("vortex") magnetization states, a metastable state has been found. This "twi......Magnetization states and hysteresis behavior of small ferromagnetic rings, of diameters 180-520 nm, have been investigated using magnetic force microscopy. In addition to the expected bi-domain ("onion") and flux-closed ("vortex") magnetization states, a metastable state has been found....... This "twisted" state contains a 360degrees domain wall which can exist over a wide range of applied fields. Four possible configurations of the twisted state are possible. Micromagnetic modeling shows that the twisted state is stabilised in small diameter, narrow rings. Additionally, more complex configurations...

Report on residual radioactive materials on public or acquired lands of the United States

Energy Technology Data Exchange (ETDEWEB)

None

1979-07-01

This report identifies sites located on public or acquired lands of the United States containing residual radioactive materials and other radioactive waste (excluding waste resulting from the production of electric energy) and was developed in accordance with the provisions of Section 114(b) of Public Law 95-604, "Uranium Mill Tailings Radiation Control Act of 1978," enacted on November 8, 1978. Additionally, the report specifies which Federal agency has jurisdiction over such sites and, where appropriate data were available, provides a description of the radiological status of each of the sites reported. For purpose of providing a timely report t o t h e Congress, a termination date of May 31, 1979 was established for the receipt, correlation, and analysis of the input data. As of this date, residual radioactive materials and other radioactive waste have been identified by six Federal agencies at 48 sites throughout the United States. Table 1 on page vi provides a summary listing of the number of sites under the jurisdiction of each of these reporting agencies. A cross listing in tabular form by affected state is presented in Table 2 on page viii. Of the 48 sites reported, 36 are located i n three western states - Colorado (27 sites), Wyoming (5 sites), and Utah (4 sites). Based upon t h e data submitted, the sites were categorized into three broad radiological status categories -- controlled, unstabilized, and risk to the public. At controlled sites, the residue is stabilized, access t o t h e site is controlled, the s i t e is well monitored, and does not currently constitute a risk to the public. At sites in the unstabilized category, a probability exists for the spread of contamination. Sites in the risk category contain residue which represents a long-term risk to the public under present conditions. Of the 48 reported sites,. 9 (approximately 19%) could be classified in the controlled category; 38 (approximately 79%) were in the unstabilized category and

Quality of Source Water from Public-Supply Wells in the United States, 1993-2007

Science.gov (United States)

Toccalino, Patricia L.; Norman, Julia E.; Hitt, Kerie J.

2010-01-01

More than one-third of the Nation's population receives their drinking water from public water systems that use groundwater as their source. The U.S. Geological Survey (USGS) sampled untreated source water from 932 public-supply wells, hereafter referred to as public wells, as part of multiple groundwater assessments conducted across the Nation during 1993-2007. The objectives of this study were to evaluate (1) contaminant occurrence in source water from public wells and the potential significance of contaminant concentrations to human health, (2) national and regional distributions of groundwater quality, and (3) the occurrence and characteristics of contaminant mixtures. Treated finished water was not sampled. The 932 public wells are widely distributed nationally and include wells in selected parts of 41 states and withdraw water from parts of 30 regionally extensive aquifers used for public water supply. These wells are distributed among 629 unique public water systems-less than 1 percent of all groundwater-supplied public water systems in the United States-but the wells were randomly selected within the sampled hydrogeologic settings to represent typical aquifer conditions. Samples from the 629 systems represent source water used by one-quarter of the U.S. population served by groundwater-supplied public water systems, or about 9 percent of the entire U.S. population in 2008. One groundwater sample was collected prior to treatment or blending from each of the 932 public wells and analyzed for as many as six water-quality properties and 215 contaminants. Consistent with the terminology used in the Safe Drinking Water Act (SDWA), all constituents analyzed in water samples in this study are referred to as 'contaminants'. More contaminant groups were assessed in this study than in any previous national study of public wells and included major ions, nutrients, radionuclides, trace elements, pesticide compounds, volatile organic compounds (VOCs), and fecal

A graph kernel approach for alignment-free domain-peptide interaction prediction with an application to human SH3 domains.

Science.gov (United States)

Kundu, Kousik; Costa, Fabrizio; Backofen, Rolf

2013-07-01

State-of-the-art experimental data for determining binding specificities of peptide recognition modules (PRMs) is obtained by high-throughput approaches like peptide arrays. Most prediction tools applicable to this kind of data are based on an initial multiple alignment of the peptide ligands. Building an initial alignment can be error-prone, especially in the case of the proline-rich peptides bound by the SH3 domains. Here, we present a machine-learning approach based on an efficient graph-kernel technique to predict the specificity of a large set of 70 human SH3 domains, which are an important class of PRMs. The graph-kernel strategy allows us to (i) integrate several types of physico-chemical information for each amino acid, (ii) consider high-order correlations between these features and (iii) eliminate the need for an initial peptide alignment. We build specialized models for each human SH3 domain and achieve competitive predictive performance of 0.73 area under precision-recall curve, compared with 0.27 area under precision-recall curve for state-of-the-art methods based on position weight matrices. We show that better models can be obtained when we use information on the noninteracting peptides (negative examples), which is currently not used by the state-of-the art approaches based on position weight matrices. To this end, we analyze two strategies to identify subsets of high confidence negative data. The techniques introduced here are more general and hence can also be used for any other protein domains, which interact with short peptides (i.e. other PRMs). The program with the predictive models can be found at http://www.bioinf.uni-freiburg.de/Software/SH3PepInt/SH3PepInt.tar.gz. We also provide a genome-wide prediction for all 70 human SH3 domains, which can be found under http://www.bioinf.uni-freiburg.de/Software/SH3PepInt/Genome-Wide-Predictions.tar.gz. Supplementary data are available at Bioinformatics online.

Absorption and fluorescence spectroscopic characterization of BLUF domain of AppA from Rhodobacter sphaeroides

Energy Technology Data Exchange (ETDEWEB)

Zirak, P. [Institut II - Experimentelle und Angewandte Physik, Universitaet Regensburg, Universitaetstrasse 31, D-93053 Regensburg (Germany); Penzkofer, A. [Institut II - Experimentelle und Angewandte Physik, Universitaet Regensburg, Universitaetstrasse 31, D-93053 Regensburg (Germany)], E-mail: alfons.penzkofer@physik.uni-regensburg.de; Schiereis, T. [Institut fuer Biologie, Experimentelle Biophysik, Humboldt-Universitaet zu Berlin, Invalidenstrasse 42, D-10115 Berlin (Germany); Hegemann, P. [Institut fuer Biologie, Experimentelle Biophysik, Humboldt-Universitaet zu Berlin, Invalidenstrasse 42, D-10115 Berlin (Germany); Jung, A. [Max-Planck-Institut fuer medizinische Forschung, Abteilung Biomolekulare Mechanismen, Jahnstrasse 29, D-69120 Heidelberg (Germany); Schlichting, I. [Max-Planck-Institut fuer medizinische Forschung, Abteilung Biomolekulare Mechanismen, Jahnstrasse 29, D-69120 Heidelberg (Germany)

2005-08-08

The BLUF domain of the transcriptional anti-repressor protein AppA from the non-sulfur anoxyphototrophic purple bacterium Rhodobacter sphaeroides was characterized by absorption and emission spectroscopy. The BLUF domain constructs AppA{sub 148} (consisting of amino-acid residues 1-148) and AppA{sub 126} (amino-acid residues 1-126) are investigated. The cofactor of the investigated domains is found to consist of a mixture of the flavins riboflavin, FMN, and FAD. The dark-adapted domains exist in two different active receptor conformations (receptor states) with different sub-nanosecond fluorescence lifetimes (BLUF{sub r,f} and BLUF{sub r,sl}) and a small non-interacting conformation (BLUF{sub nc}). The active receptor conformations are transformed to putative signalling states (BLUF{sub s,f} and BLUF{sub s,sl}) of low fluorescence efficiency and picosecond fluorescence lifetime by blue-light excitation (light-adapted domains). In the dark at room temperature both signalling states recover back to the initial receptor states with a time constant of about 17 min. A quantum yield of signalling state formation of about 25% was determined by intensity dependent transmission measurements. A photo-cycle scheme is presented including photo-induced charge transfer complex formation, charge recombination, and protein binding pocket reorganisation.

Public health against a centralized state: institutions and welfare services in the province of Mendoza during the first Peronism

Directory of Open Access Journals (Sweden)

Ivana Hirschegger

2016-10-01

Full Text Available This research analyzes the state action in public health during the first Peronism and engages on some factors that determined the success or failure of policies at provincial level. The work also refers , through concrete examples , to smaller territorial units such as municipalities , while application areas of public policy or executors of them. Some of the questions that were attempted to answer what extent the new changes in the state structure were accompanied by concrete actions that have a bearing on the living conditions of the population? What obstacles limited government action? the realization of public works will be included in this analysis by the state , staff in charge , as well as investments in other resources necessary for adequate medical care.

Using Sentence-Level Classifiers for Cross-Domain Sentiment Analysis

Science.gov (United States)

2014-09-01

National Defence, 2014 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2014 DRDC-RDDC...domain sentiment classification via spectral feature alignment. In Proceedings of the 19th international conference on World Wide Web, WWW ’10...Dennis, S. 5. DATE OF PUBLICATION (Month and year of publication of document.) September 2014 6a. NO. OF PAGES (Total containing information

Performance Assessment in CTE: Focusing on the Cognitive, Psychomotor ...and Affective Domains

Science.gov (United States)

Washer, Bart; Cochran, Lori

2012-01-01

When a student is performing in the psychomotor domain, the authors believe the student is also performing in the cognitive domain (sequencing steps, evaluating the situation) and in the affective domain (appreciating a job well done, quality control, safety). As Dabney Doty, former instructor at the University of Central Missouri, stated, "There…

Public health implications of changing rodent importation patterns— United States, 1999–2013

Science.gov (United States)

Lankau, Emily W.; Sinclair, Julie R.; Schroeder, Betsy A.; Galland, G. Gale; Marano, Nina

2015-01-01

Summary The United States imports a large volume of live wild and domestic animal species; these animals pose a demonstrated risk for introduction of zoonotic diseases. Rodents are imported for multiple purposes, including scientific research, zoo exhibits, and the pet trade. Current U.S. public health regulatory restrictions specific to rodent importation pertain only to those of African origin. To understand the impacts of these regulations and the potential public health risks of international rodent trade to the United States, we evaluated live rodent import records during 1999 –2013 by shipment volume and geographic origin, source (e.g., wild -caught versus captive-or commercially bred), intended purpose, and rodent taxonomy. Live rodent imports increased from 2,737 animals during 1999 to 173,761 animals during 2013. Increases in both the number and size of shipments contributed to this trend. The proportion of wild-captured imports declined from 75% during 1999 to guinea pigs, and hamsters arriving from other countries in North America were predominant taxa underlying this trend . After 2003, African-origin imports became sporadic events under the federal permit process. These patterns suggest development of large -scale captive rodent breeding markets abroad for commercial sale in the United States. While the shift from wild-captured imports alleviates many conservation concerns and risks for novel disease emergence, such consolidated sourcing might elevate exposure risks for zoonotic diseases associated with high-density rodent breeding(e.g. , lymphocytic choriomeningitis or salmonellosis). A responsive border health system must periodically re-evaluate importation regulations in conjunction with key stakeholders to ensure a balance between the economic benefits of rodent trade against the potential public health risks. PMID:26245515

A domain-independent descriptive design model and its application to structured reflection on design processes

NARCIS (Netherlands)

Reymen, Isabelle; Hammer, D.K.; Kroes, P.A.; van Aken, Joan Ernst; van Aken, J.E.; Dorst, C.H.; Bax, M.F.T.; Basten, T

2006-01-01

Domain-independent models of the design process are an important means for facilitating interdisciplinary communication and for supporting multidisciplinary design. Many so-called domain-independent models are, however, not really domain independent. We state that to be domain independent, the

Reclaiming public space: designing for public interaction with private devices

DEFF Research Database (Denmark)

Eriksson, Eva; Hansen, Thomas Riisgaard; Lykke-Olesen, Andreas

2007-01-01

. In this paper we explore the implications of interacting in public space and how technology can be rethought to not only act as personal devices, but be the tool to reclaim the right and possibility to interact in public spaces. We introduce information exchange, social support and regulation as three central......Public spaces are changing from being ungoverned places for interaction to be more formalized, controlled, less interactive, and designed places aimed at fulfilling a purpose. Simultaneously, new personal mobile technology aims at providing private individual spaces in the public domain...... aspects for reclaiming public space. The PhotoSwapper application is presented as an example of a system designed to integrate pervasive technology in a public setting. The system is strongly inspired by the activities at a traditional market place. Based on the design of the application we discuss four...

[The activity of the State Sanitary Inspectorate after implementation of the act of January, 23 2009 "Amending certain acts regarding reorganization and redistribution of competences of the public administration at the provincial level"].

Science.gov (United States)

Rudaś, Dariusz; Skórczewski, Krzysztof

2011-01-01

The restructuring of the State Sanitary Inspectorate was determined by the need to adjust the existing system to the new structure- and task-oriented standards introduced by the administrative reforms at the provincial level. This brought about a lot of changes in the way State County Sanitary Inspectors operate. For first few months after the enforcement of the Act of January 23.2009 amending certain acts regarding reorganization and redistribution of competences of the public administration at the provincial level (Journal of Laws, No. 92, item. 753, 2009) brought about a lot of ambiguities and expectations. Such unresolved issues are typical for the initial or transition period after implementation of a new law. The approach to the operation of the State Sanitary Inspectorate at the county level depicted in the article lays the emphasis on the challenges in the legal and task-oriented domain that arose after coming into force of the aforementioned amendment. By way of conclusion, the authors of the article briefly summaries the practical outcomes of the transformations undergone by the State Sanitary Inspectorate at the county level.

Value of Public Health Funding in Preventing Hospital Bloodstream Infections in the United States.

Science.gov (United States)

Whittington, Melanie D; Bradley, Cathy J; Atherly, Adam J; Campbell, Jonathan D; Lindrooth, Richard C

2017-11-01

To estimate the association of 1 activity of the Prevention and Public Health Fund with hospital bloodstream infections and calculate the return on investment (ROI). The activity was funded for 1 year (2013). A difference-in-differences specification evaluated hospital standardized infection ratios (SIRs) before funding allocation (years 2011 and 2012) and after funding allocation (years 2013 and 2014) in the 15 US states that received the funding compared with hospital SIRs in states that did not receive the funding. We estimated the association of the funded public health activity with SIRs for bloodstream infections. We calculated the ROI by dividing cost offsets from infections averted by the amount invested. The funding was associated with a 33% (P < .05) reduction in SIRs and an ROI of $1.10 to $11.20 per $1 invested in the year of funding allocation (2013). In 2014, after the funding stopped, significant reductions were no longer evident. This activity was associated with a reduction in bloodstream infections large enough to recoup the investment. Public health funding of carefully targeted areas may improve health and reduce health care costs.

US Public Opinion on Carrying Firearms in Public Places.

Science.gov (United States)

Wolfson, Julia A; Teret, Stephen P; Azrael, Deborah; Miller, Matthew

2017-06-01

To estimate US public opinion, overall and by gun ownership status, about the public places where legal gun owners should be allowed to carry firearms. We fielded an online survey among 3949 adults, including an oversample of gun owners and veterans, in April 2015. We used cross-tabulations with survey weights to generate nationally representative estimates. Fewer than 1 in 3 US adults supported gun carrying in any of the specified venues. Support for carrying in public was consistently higher among gun owners than among non-gun owners. Overall, support for carrying in public was lowest for schools (19%; 95% confidence interval [CI] = 16.7, 21.1), bars (18%; 95% CI = 15.9, 20.6), and sports stadiums (17%; 95% CI = 15.0, 19.5). Most Americans, including most gun owners, support restricting public places legal gun owners can carry firearms. These views contrast sharply with the current trend in state legislatures of expanding where, how, and by whom guns can be carried in public. Recent state laws and proposed federal legislation that would force states to honor out-of-state concealed carry permits are out of step with American public opinion.

BUILDING AN EU MEMBER STATE THROUGH DEMOCRACY PROMOTION: THE CASE OF CROATIA'S PUBLIC ADMINISTRATION REFORM

Directory of Open Access Journals (Sweden)

Sonja Grimm

2013-01-01

Full Text Available This contribution studies the process of building an EU member state through democracy promotion in the case of Croatia with a special focus on two reform initiatives in the field of Public Administration Reform (PAR. Croatia’s experience is representative of intense efforts of the international community to overcome the consequences of violent state dissolution and civil war. The EU in particular has assisted post-conflict democratization with diplomatic initiatives, the provision of aid, and political conditionality. The Croatian political elite showed great willingness to implement democratic reforms, while at the same time remaining critical of what they viewed as ‘too much’ external interference in domestic state affairs. Based on 30 interviews with Croatian officials, Croatian civil society actors, members of the EU delegation and other representatives of the International donor community, we empirically assess progress and setbacks in Croatia’s public administration reform and explain why some reform initiatives have been successfully implemented while others are still pending.

Nuclear power in the United States: public views and industry actions

International Nuclear Information System (INIS)

Poncelet, C.G.

1981-01-01

The author describes the public policy environment that surround the nuclear power program in the United States and the social implications as an expression of the public opinion, the mass media as a source of information and the organized opposition movements with their socio-political motivations. The political climate after the new Republican government is also analysed as well as the communication efforts of the nuclear industry to ascertain the need of assertive programs and the sense of cooperation and commitment on the part of both the nuclear and electric utility industries. The general situation is characterized on the one hand by the growing acknowledgement of the need for nuclear power development in an economy dominated by the oil crisis; on the other hand, it is the financial crisis faced by electric utilities which directly impacts on this future development. (AF)

Depiction of global trends in publications on mobile health

Directory of Open Access Journals (Sweden)

Shahla Foozonkhah

2017-07-01

Full Text Available Background: Variety of mobile health initiatives in different levels have been undertaken across many countries. Trends of these initiatives can be reflected in the research published in m-health domain. Aim: This paper aims to depict global trends in the published works on m-health topic. Materials and Methods: The Web of Science database was used to identify all relevant published papers on mobile health domain worldwide. The search was conducted on documents published from January 1898 to December 2014. The criteria for searching were set to be “mHealth” or “Mobile health” or “m health” or “m_health” or “m-health” in topics. Results: Findings revealed an increasing trend of citations and publications on m-health research since 2012. English was the first most predominant language of the publication. The US had the highest number of publication with 649 papers; however, the Netherlands ranked first after considering publication number in terms of countries population. “Studies in Health Technology and Informatics” was the source title with highest number of publications on mobile health topics. Conclusion: Trend of research observed in this study indicates the continuing growth is happening in mobile health domain. This may imply that the new model of health-care delivery is emerging. Further research is needed to specify directions of mobile health research. It is necessary to identify and prioritize the research gaps in this domain.

Rascal: A domain specific language for source code analysis and manipulation

NARCIS (Netherlands)

P. Klint (Paul); T. van der Storm (Tijs); J.J. Vinju (Jurgen); A. Walenstein; S. Schuppe

2009-01-01

htmlabstractMany automated software engineering tools require tight integration of techniques for source code analysis and manipulation. State-of-the-art tools exist for both, but the domains have remained notoriously separate because different computational paradigms fit each domain best. This

RASCAL : a domain specific language for source code analysis and manipulationa

NARCIS (Netherlands)

Klint, P.; Storm, van der T.; Vinju, J.J.

2009-01-01

Many automated software engineering tools require tight integration of techniques for source code analysis and manipulation. State-of-the-art tools exist for both, but the domains have remained notoriously separate because different computational paradigms fit each domain best. This impedance

Atomic resolution imaging of ferroelectric domains

International Nuclear Information System (INIS)

Bursill, L.A.

1997-01-01

Electron optical principles involved in obtaining atomic resolution images of ferroelectric domains are reviewed, including the methods available to obtain meaningful interpretation and analysis of the image detail in terms of the atomic structures. Recent work is concerned with establishing the relationship between the essentially static chemical nanodomains and the spatial and temporal fluctuations of the nanoscale polar domains present in the relaxor class of materials, including lead scandium tantalate (PST) and lead magnesium niobate (PMN). Correct interpretation of the images required use of Next Nearest Neighbour Ising model simulations for the chemical domain textures upon which we must superimpose the polar domain textures; an introduction to this work is presented. A thorough analysis of the atomic scale chemical inhomogeneities, based upon the HRTEM results, has lead to an improved formulation of the theory of the dielectric response of PMN and PST, which is capable to predict the observed temperature and frequency dependence. HRTEM may be combined with solid state and statistical physics principles to provide a deeper understanding of structure/property relationships. 15 refs., 6 figs

78 FR 17652 - Tri-State Generation and Transmission Association, Inc. v. Public Service Company of New Mexico...

Science.gov (United States)

2013-03-22

... Generation and Transmission Association, Inc. v. Public Service Company of New Mexico; Notice of Complaint... CFR 385.206 and 18 CFR 385.212, Tri-State Generation and Transmission Association, Inc. (Complainant), filed a complaint against the Public Service Company of New Mexico (Respondent or PNM) alleging that...

Temporary formation of highly conducting domain walls for non-destructive read-out of ferroelectric domain-wall resistance switching memories

Science.gov (United States)

Jiang, Jun; Bai, Zi Long; Chen, Zhi Hui; He, Long; Zhang, David Wei; Zhang, Qing Hua; Shi, Jin An; Park, Min Hyuk; Scott, James F.; Hwang, Cheol Seong; Jiang, An Quan

2018-01-01

Erasable conductive domain walls in insulating ferroelectric thin films can be used for non-destructive electrical read-out of the polarization states in ferroelectric memories. Still, the domain-wall currents extracted by these devices have not yet reached the intensity and stability required to drive read-out circuits operating at high speeds. This study demonstrated non-destructive read-out of digital data stored using specific domain-wall configurations in epitaxial BiFeO3 thin films formed in mesa-geometry structures. Partially switched domains, which enable the formation of conductive walls during the read operation, spontaneously retract when the read voltage is removed, reducing the accumulation of mobile defects at the domain walls and potentially improving the device stability. Three-terminal memory devices produced 14 nA read currents at an operating voltage of 5 V, and operated up to T = 85 °C. The gap length can also be smaller than the film thickness, allowing the realization of ferroelectric memories with device dimensions far below 100 nm.

A novel square-root domain realization of first order all-pass filter

OpenAIRE

ÖLMEZ, Sinem; ÇAM, Uğur

2010-01-01

In this paper, a new square-root domain, first order, all-pass filter based on the MOSFET square law is presented. The proposed filter is designed by using nonlinear mapping on the state variables of a state space description of the transfer function. To the best knowledge of the authors, the filter is the first square-root domain first order all-pass structure designed by using state space synthesis method in the literature. The center frequency of the all-pass filter is not only a...

Competition and deregulation in the electric industry. A study of organizational change: The New York State Public Service Commission

Science.gov (United States)

Ashley, Deborah J. Cordaro

2000-11-01

Public organizations are formed in response to societal needs. They collect taxes, educate children, enforce laws and provide protection to the environment, the nation and consumers. One such organization is the New York State Public Service Commission. In 1907, legislation was passed to form the New York State Public Service Commission the first regulatory body of its kind in the United States. Its mission was to provide safe, reliable and reasonably priced electricity. Subsequently, this became the model that was implemented in every state in the nation. The past decade heralds an era of competition and a lessening of regulatory control. The telephone, natural gas and airline industries are in various stages of deregulation, and the electric industry is beginning down this path as well. In an environment such as this, are regulatory organizations necessary, and if they are, how can they organize to meet the new societal requirements? The case of the New York State Public Service Commission at this point in time offers a real time study of a regulatory body immersed in an environment that is calling for competition and an end to big government. Utilizing case studies of industries that have deregulated, or are in the process of deregulating, indicates a future societal need for regulations. This result does not lead to a conclusion that organizational change is unnecessary. This Dissertation will lay out the current organizational structure of the Public Service Commission, give an overview of the environmental signals, describe the mission/core values, and illustrate general political and employee factors that are indigenous to public service. Utilizing both classic and current organizational theory, an evaluation will be made of the Commission's need for change, their ability to change, and obstacles they may encounter.

PREFACE: Domain wall dynamics in nanostructures Domain wall dynamics in nanostructures

Science.gov (United States)

Marrows, C. H.; Meier, G.

2012-01-01

forms of ordered phases such as antiferromagnetism and ferroelectricity. We would like to thank the scientists from all over the world who happily agreed to contribute their latest results to this special issue, and the Journal of Physics: Condensed Matter staff for their help, patience and professionalism. In such a fast-moving field it is not possible to give a definitive account, and this special issue can be no more than a snapshot of the current state of knowledge regarding this topic. Nevertheless, we hope that this collection of papers is a useful resource for experienced workers in the field, forms a useful introduction to researchers early in their careers and inspires others in related areas of nanotechnology to enter into the study of domain dynamics in nanostructures. Domain wall dynamics in nanostructures contents Temperature estimation in a ferromagnetic Fe-Ni nanowire involving a current-driven domain wall motionA Yamaguchi, A Hirohata, T Ono and H Miyajima Magnetization reversal in magnetic nanostripes via Bloch wall formation M Zeisberger and R Mattheis Magnetic soft x-ray microscopy of the domain wall depinning process in permalloy magnetic nanowiresMi-Young Im, Lars Bocklage, Guido Meier and Peter Fischer Domain wall propagation in meso- and nanoscale ferroelectrics R G P McQuaid, M McMillen, L-W Chang, A Gruverman and J M Gregg Transverse and vortex domain wall structure in magnetic nanowires with uniaxial in-plane anisotropyM T Bryan, S Bance, J Dean, T Schrefl and D A Allwood The stochastic nature of the domain wall motion along high perpendicular anisotropy strips with surface roughness Eduardo Martinez Temperature-dependent dynamics of stochastic domain-wall depinning in nanowiresClemens Wuth, Peter Lendecke and Guido Meier Controlled pinning and depinning of domain walls in nanowires with perpendicular magnetic anisotropyTheo Gerhardt, André Drews and Guido Meier The interaction of transverse domain wallsBenjamin Krüger The increase of the

Prognostic framing of stakeholders' subjectivities: A case of all-terrain vehicle management on state public lands

Science.gov (United States)

Stanley T. Asah; David N. Bengston; Keith Wendt; Leif. DeVaney

2012-01-01

Management of all-terrain vehicle (ATV) use on Minnesota state forest lands has a contentious history and land managers are caught between ATV riders, nonmotorized recreationists, private landowners, and environmental advocates. In this paper, we demonstrate the usefulness of framing distinct perspectives about ATV management on Minnesota state public forests,...

77 FR 7600 - Notice of Segregation of Public Lands in the State of Arizona for the Restoration Design Energy...

Science.gov (United States)

2012-02-13

...] Notice of Segregation of Public Lands in the State of Arizona for the Restoration Design Energy Project... Arizona from all forms of appropriation under the public land laws, including the mining law, but... the Restoration Design Energy Project (RDEP). The public lands contained in this segregation total...

Navigating the evidentiary turn in public health: Sensemaking strategies to integrate genomics into state-level chronic disease prevention programs.

Science.gov (United States)

Senier, Laura; Smollin, Leandra; Lee, Rachael; Nicoll, Lauren; Shields, Michael; Tan, Catherine

2018-06-23

In the past decade, healthcare delivery has faced two major disruptions: the mapping of the human genome and the rise of evidence-based practice. Sociologists have documented the paradigmatic shift towards evidence-based practice in medicine, but have yet to examine its effect on other health professions or the broader healthcare arena. This article shows how evidence-based practice is transforming public health in the United States. We present an in-depth qualitative analysis of interview, ethnographic, and archival data to show how Michigan's state public health agency has navigated the turn to evidence-based practice, as they have integrated scientific advances in genomics into their chronic disease prevention programming. Drawing on organizational theory, we demonstrate how they managed ambiguity through a combination of sensegiving and sensemaking activities. Specifically, they linked novel developments in genomics to a long-accepted public health planning model, the Core Public Health Functions. This made cutting edge advances in genomics more familiar to their peers in the state health agency. They also marshaled state-specific surveillance data to illustrate the public health burden of hereditary cancers in Michigan, and to make expert panel recommendations for genetic screening more locally relevant. Finally, they mobilized expertise to help their internal colleagues and external partners modernize conventional public health activities in chronic disease prevention. Our findings show that tools and concepts from organizational sociology can help medical sociologists understand how evidence-based practice is shaping institutions and interprofessional relations in the healthcare arena. Copyright © 2018 Elsevier Ltd. All rights reserved.

Switching behavior and novel stable states of magnetic hexagonal nanorings

Energy Technology Data Exchange (ETDEWEB)

Yasir Rafique, M., E-mail: myasir.rafique@ciitlahore.edu.pk [Department of Physics, COMSATS Institute of Information Technology, Lahore 54000 (Pakistan); Pan, Liqing; Guo, Zhengang [College of Science and Research Institute for New Energy, China Three Gorges University, Yichang 443002 (China)

2017-06-15

Micromagnetic simulations for Cobalt hexagonal shape nanorings show onion (O) and vortex state (V) along with new state named “tri-domain state”. The tri-domain state is observed in sufficiently large width of ring. The magnetic reversible mechanism and transition of states are explained with help of vector field display. The transitions from one state to other occur by propagation of domain wall. The vertical parts of hexagonal rings play important role in developing the new “tri-domain” state. The behaviors of switching fields from onion to tri-domain (HO-Tr), tri-domain to vortex state (HTr-V) and vortex to onion state and “states size” are discussed in term of geometrical parameter of ring.

76 FR 6171 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Public Meeting...

Science.gov (United States)

2011-02-03

... International Law (ACPIL): Public Meeting on Family Law The Department of State, Office of Legal Adviser, Office of Private International Law would like to give notice of a public meeting to discuss preparations for the upcoming Special Commission of the Hague Conference on Private International Law on the 1980...

Public health program capacity for sustainability: a new framework.

Science.gov (United States)

Schell, Sarah F; Luke, Douglas A; Schooley, Michael W; Elliott, Michael B; Herbers, Stephanie H; Mueller, Nancy B; Bunger, Alicia C

2013-02-01

Public health programs can only deliver benefits if they are able to sustain activities over time. There is a broad literature on program sustainability in public health, but it is fragmented and there is a lack of consensus on core constructs. The purpose of this paper is to present a new conceptual framework for program sustainability in public health. This developmental study uses a comprehensive literature review, input from an expert panel, and the results of concept-mapping to identify the core domains of a conceptual framework for public health program capacity for sustainability. The concept-mapping process included three types of participants (scientists, funders, and practitioners) from several public health areas (e.g., tobacco control, heart disease and stroke, physical activity and nutrition, and injury prevention). The literature review identified 85 relevant studies focusing on program sustainability in public health. Most of the papers described empirical studies of prevention-oriented programs aimed at the community level. The concept-mapping process identified nine core domains that affect a program's capacity for sustainability: Political Support, Funding Stability, Partnerships, Organizational Capacity, Program Evaluation, Program Adaptation, Communications, Public Health Impacts, and Strategic Planning. Concept-mapping participants further identified 93 items across these domains that have strong face validity-89% of the individual items composing the framework had specific support in the sustainability literature. The sustainability framework presented here suggests that a number of selected factors may be related to a program's ability to sustain its activities and benefits over time. These factors have been discussed in the literature, but this framework synthesizes and combines the factors and suggests how they may be interrelated with one another. The framework presents domains for public health decision makers to consider when developing

The domain theory: patterns for knowledge and software reuse

National Research Council Canada - National Science Library

Sutcliffe, Alistair

2002-01-01

..., retrieval system, or any other means, without prior written permission of the publisher. Lawrence Erlbaum Associates, Inc., Publishers 10 Industrial Avenue Mahwah, New Jersey 07430 Library of Congress Cataloging-in-Publication Data Sutcliffe, Alistair, 1951- The domain theory : patterns for knowledge and software reuse / Alistair Sutcl...

State health managers' perceptions of the Public Health Action Organizational Contract in the State of Ceará, Brazil.

Science.gov (United States)

Goya, Neusa; Andrade, Luiz Odorico Monteiro de; Pontes, Ricardo José Soares; Tajra, Fábio Solon; Barreto, Ivana Cristina de Holanda Cunha

2017-04-01

The Public Health Action Organizational Contract (COAP) / Decree 7.508/2011 aimed to seal health agreements made between federated entities to promote the cooperative governance and management of Health Regions. A qualitative study was carried out adopting a hermeneutic approach to understand state health managers' perceptions of the elaboration and effects of the COAP in the State of Ceará. Open-ended interviewees and documental analysis were conducted. It was observed that the COAP led to the strengthening of regionalization in the government sphere; institutional gains through the implementation of ombudsmen and the National System of Pharmaceutical Care Management; increased information about the state health system's workforce; and health budget transparency. The following problems were (re)visited: institutional weakness in the operation of the network; limited state capacity for regulation of care; and underfunding. Regional governance was restricted to the government sphere, coordinated by the state, and was characterized by a predominantly bureaucratic and hierarchical governance structure. The COAP inaugurated a contractual interfederative model of regionalization, but revealed the institutional weaknesses of the SUS and its lacks of capacity to fulfill its principles as the structural problems of the three-tiered model go unaddressed.

Does co-creation impact public service delivery? The importance of state and governance traditions

NARCIS (Netherlands)

Voorberg, Willem; Bekkers, Victor; Flemig, Sophie; Timeus, Krista; Tõnurist, Piret; Tummers, L.G.

2017-01-01

Co-creation in public service delivery requires partnerships between citizens and civil servants. The authors argue that whether or not these partnerships will be successful depends on state and governance traditions (for example a tradition of authority sharing or consultation). These traditions

Partners in Public Health: Public Health Collaborations With Schools of Pharmacy, 2015.

Science.gov (United States)

DiPietro Mager, Natalie A; Ochs, Leslie; Ranelli, Paul L; Kahaleh, Abby A; Lahoz, Monina R; Patel, Radha V; Garza, Oscar W; Isaacs, Diana; Clark, Suzanne

To collect data on public health collaborations with schools of pharmacy, we sent a short electronic survey to accredited and preaccredited pharmacy programs in 2015. We categorized public health collaborations as working or partnering with local and/or state public health departments, local and/or state public health organizations, academic schools or programs of public health, and other public health collaborations. Of 134 schools, 65 responded (49% response rate). Forty-six (71%) responding institutions indicated collaborations with local and/or state public health departments, 34 (52%) with schools or programs of public health, and 24 (37%) with local and/or state public health organizations. Common themes of collaborations included educational programs, community outreach, research, and teaching in areas such as tobacco control, emergency preparedness, chronic disease, drug abuse, immunizations, and medication therapy management. Interdisciplinary public health collaborations with schools of pharmacy provide additional resources for ensuring the health of communities and expose student pharmacists to opportunities to use their training and abilities to affect public health. Examples of these partnerships may stimulate additional ideas for possible collaborations between public health organizations and schools of pharmacy.

Piezoelectric and electrooptic ferroics - qualitative domain and tensor characteristics

Czech Academy of Sciences Publication Activity Database

Janovec, Václav; Čmelík, M.; Machonský, L.

2010-01-01

Roč. 83, č. 9 (2010), 670-681 ISSN 0141-1594 Institutional research plan: CEZ:AV0Z10100520 Keywords : ferroic crystals * piezoelectric materials * electrooptic materials * species * orientation states * tensor domain states Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.006, year: 2010

The Impact of State Preemption of Local Smoking Restrictions on Public Health Protections and Changes in Social Norms

Directory of Open Access Journals (Sweden)

Paul D. Mowery

2012-01-01

Full Text Available Introduction. Preemption is a legislative or judicial arrangement in which a higher level of government precludes lower levels of government from exercising authority over a topic. In the area of smoke-free policy, preemption typically takes the form of a state law that prevents communities from adopting local smoking restrictions. Background. A broad consensus exists among tobacco control practitioners that preemption adversely impacts tobacco control efforts. This paper examines the effect of state provisions preempting local smoking restrictions in enclosed public places and workplaces. Methods. Multiple data sources were used to assess the impact of state preemptive laws on the proportion of indoor workers covered by smoke-free workplace policies and public support for smoke-free policies. We controlled for potential confounding variables. Results. State preemptive laws were associated with fewer local ordinances restricting smoking, a reduced level of worker protection from secondhand smoke, and reduced support for smoke-free policies among current smokers. Discussion. State preemptive laws have several effects that could impede progress in secondhand smoke protections and broader tobacco control efforts. Conclusion. Practitioners and advocates working on other public health issues should familiarize themselves with the benefits of local policy making and the potential impact of preemption.

AMPLIFICAREA RELAłIEI AUDITULUI PUBLIC INTERN CU AUDITUL PUBLIC EXTERN

Directory of Open Access Journals (Sweden)

Ioan Alexandru Szabo

2011-01-01

Full Text Available The paper deals with the issue of functional relations between the structure of theinternal audit and external audit in the public domain. The introduction isaddressed to international standards and regulatory framework that stipulates theneed for consolidation of the cooperation relations between the two categories ofprofessionals, namely, internal auditors and external public auditors. The authoremphasizes the importance of developing and of signing the Protocol ofcooperation and collaboration between the two audit authorities that are the Courtof Accounts and The Public Finance that support the professional partnership. Thearticle also presents the terms of the Protocol signed between external audit andinternal audit in the public sector. Finally, it is concluded that the increasing therole of internal audit in the implementation and development of management andinternal control system within public entities, is conditioned by the functionality ofthe collaboration and cooperation relationships between the two audits.

The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies.

Science.gov (United States)

Ziemba, Brian P; Pilling, Carissa; Calleja, Véronique; Larijani, Banafshé; Falke, Joseph J

2013-07-16

Phosphoinositide-dependent kinase-1 (PDK1) is an essential master kinase recruited to the plasma membrane by the binding of its C-terminal PH domain to the signaling lipid phosphatidylinositol-3,4,5-trisphosphate (PIP3). Membrane binding leads to PDK1 phospho-activation, but despite the central role of PDK1 in signaling and cancer biology, this activation mechanism remains poorly understood. PDK1 has been shown to exist as a dimer in cells, and one crystal structure of its isolated PH domain exhibits a putative dimer interface. It has been proposed that phosphorylation of PH domain residue T513 (or the phospho-mimetic T513E mutation) may regulate a novel PH domain dimer-monomer equilibrium, thereby converting an inactive PDK1 dimer to an active monomer. However, the oligomeric states of the PH domain on the membrane have not yet been determined, nor whether a negative charge at position 513 is sufficient to regulate its oligomeric state. This study investigates the binding of purified wild-type (WT) and T513E PDK1 PH domains to lipid bilayers containing the PIP3 target lipid, using both single-molecule and ensemble measurements. Single-molecule analysis of the brightness of the fluorescent PH domain shows that the PIP3-bound WT PH domain on membranes is predominantly dimeric while the PIP3-bound T513E PH domain is monomeric, demonstrating that negative charge at the T513 position is sufficient to dissociate the PH domain dimer and is thus likely to play a central role in PDK1 monomerization and activation. Single-molecule analysis of two-dimensional (2D) diffusion of PH domain-PIP3 complexes reveals that the dimeric WT PH domain diffuses at the same rate as a single lipid molecule, indicating that only one of its two PIP3 binding sites is occupied and there is little penetration of the protein into the bilayer as observed for other PH domains. The 2D diffusion of T513E PH domain is slower, suggesting the negative charge disrupts local structure in a way that allows

Domain-enhanced analysis of microarray data using GO annotations.

Science.gov (United States)

Liu, Jiajun; Hughes-Oliver, Jacqueline M; Menius, J Alan

2007-05-15

New biological systems technologies give scientists the ability to measure thousands of bio-molecules including genes, proteins, lipids and metabolites. We use domain knowledge, e.g. the Gene Ontology, to guide analysis of such data. By focusing on domain-aggregated results at, say the molecular function level, increased interpretability is available to biological scientists beyond what is possible if results are presented at the gene level. We use a 'top-down' approach to perform domain aggregation by first combining gene expressions before testing for differentially expressed patterns. This is in contrast to the more standard 'bottom-up' approach, where genes are first tested individually then aggregated by domain knowledge. The benefits are greater sensitivity for detecting signals. Our method, domain-enhanced analysis (DEA) is assessed and compared to other methods using simulation studies and analysis of two publicly available leukemia data sets. Our DEA method uses functions available in R (http://www.r-project.org/) and SAS (http://www.sas.com/). The two experimental data sets used in our analysis are available in R as Bioconductor packages, 'ALL' and 'golubEsets' (http://www.bioconductor.org/). Supplementary data are available at Bioinformatics online.

Exposure to simultaneous sedentary behavior domains and sociodemographic factors associated in public servants

Directory of Open Access Journals (Sweden)

Fernanda Cerveira Fronza

2017-11-01

Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2017v19n4p469   Exposure to sedentary behavior may contribute to health problems. This study aimed to estimate the prevalence of exposure to simultaneous sedentary behavior domains and verify associated sociodemographic characteristics among technical and administrative servers of a Brazilian university. This is a cross-sectional epidemiological study carried out with 623 technical and administrative servers. Sedentary behavior was identified through a questionnaire in the following domains: commuting (active / passive, sitting time at work, daily time spent watching television and computer use (≥3 hours / day. Sociodemographic variables were age, sex and educational level. The prevalence of servers that had one, two, three and four simultaneous sedentary behavior was 28.4%, 43.2%, 22.5% and 4.3%, respectively. Women were more likely to have three sedentary behavior simultaneously (OR = 1.61, CI 95% = 1.02, 2.56. Servers with 9-11 years of schooling were less exposed to two (OR = 0.27, CI 95% = 0.17, 0.44, three (OR = 0.39, CI 95% = 0.23, 0.66 and four (OR = 0.22, CI 95% = 0.07; 0.69 sedentary behavior simultaneously and those over 12 years of schooling were less likely of having two (OR = 0.22, CI 95% = 0.10; 0.49 and three (OR = 0.15, CI 95% = 0.05, 0.46 sedentary behavior simultaneously. More than half of servers have two sedentary behavior during the week. Having sedentary behavior in more than one domain simultaneously was associated with sex and educational level.

Measuring up to the Model: A Ranking of State Public Charter School Laws. Ninth Annual Edition

Science.gov (United States)

Ziebarth, Todd; Palmer, Louann Bierlein

2018-01-01

This ninth edition of "Measuring up to the Model: A Ranking of State Charter School Laws" presents the latest activity in charter public school legislation across the country. For the second year in a row, the 2018 rankings measure each state's charter school law against the National Alliance's updated model charter school law, "New…

Information Access in Rural Areas of the United States: The Public Library's Role in the Digital Divide and the Implications of Differing State Funding Models

Science.gov (United States)

Thiele, Jennifer

2016-01-01

In the United States, individual states have different means of determining and distributing funding. This influences library service and access to information particularly as it pertains to critical Internet access. Funding and service trends have changed, especially as it relates to public libraries, with some modifications working to their…

Convectons in periodic and bounded domains

International Nuclear Information System (INIS)

Mercader, Isabel; Batiste, Oriol; Alonso, Arantxa; Knobloch, Edgar

2010-01-01

Numerical continuation is used to compute spatially localized convection in a binary fluid with no-slip laterally insulating boundary conditions and the results are compared with the corresponding ones for periodic boundary conditions (PBC). The change in the boundary conditions produces a dramatic change in the snaking bifurcation diagram that describes the organization of localized states with PBC: the snaking branches turn continuously into a large amplitude state that resembles periodic convection with defects at the sidewalls. Odd parity convectons are more affected by the boundary conditions since the sidewalls suppress the horizontal pumping action that accompanies these states in spatially periodic domains.

Convectons in periodic and bounded domains

Energy Technology Data Exchange (ETDEWEB)

Mercader, Isabel; Batiste, Oriol; Alonso, Arantxa [Departament de Fisica Aplicada, Universitat Politecnica de Catalunya, Barcelona (Spain); Knobloch, Edgar [Department of Physics, University of California, Berkeley, CA 94720 (United States)

2010-04-15

Numerical continuation is used to compute spatially localized convection in a binary fluid with no-slip laterally insulating boundary conditions and the results are compared with the corresponding ones for periodic boundary conditions (PBC). The change in the boundary conditions produces a dramatic change in the snaking bifurcation diagram that describes the organization of localized states with PBC: the snaking branches turn continuously into a large amplitude state that resembles periodic convection with defects at the sidewalls. Odd parity convectons are more affected by the boundary conditions since the sidewalls suppress the horizontal pumping action that accompanies these states in spatially periodic domains.

Public and Private Regulation of the Forestry Sector: The Cases of The United States and Canada : Part 2

NARCIS (Netherlands)

van der Loos, H.Z.A.; Alimov, Andrey

This paper discusses and compares public and private forestry regulation practices in Canada and the United States. The analyses focuses on industry layout, sustainability policies and new and alternative forms of environmental governance. It concludes with an eye towards Russia, its public forestry

Public and Private Regulation of the Forestry Sector: The Cases of The United States and Canada : Part 1

NARCIS (Netherlands)

van der Loos, H.Z.A.; Alimov, Andrey

This paper discusses and compares public and private forestry regulation practices in Canada and the United States. The analyses focuses on industry layout, sustainability policies and new and alternative forms of environmental governance. It concludes with an eye towards Russia, its public forestry

The state of US trauma systems: public perceptions versus reality--implications for US response to terrorism and mass casualty events.

Science.gov (United States)

Champion, Howard R; Mabee, Marcia S; Meredith, J Wayne

2006-12-01

Injury has long been identified as the number one killer of Americans under the age of 34, and establishment of regional trauma systems and centers incorporating primary, secondary, and tertiary care and injury-prevention strategies has proved to be a vital element in reducing injury-related sequelae, deaths, and even costs. Despite these facts, trauma system development has not been given priority for funding in many local and state governments and only intermittently at the federal level. Consequently, many of the nation's trauma centers are strapped for funds to provide emergency care to their patients. In response to a 2002 Health Resources and Services Administration (HRSA) report, which identified public support as a key element in the success of trauma system development in states and communities across the United States, a Harris Interactive study was undertaken in the fall of 2004 to determine the public's attitudes, awareness, and knowledge concerning the nature and availability of trauma care and systems of trauma care. Results of the poll were contrasted with current data on the state of US trauma systems to determine the degree of correspondence. Results of the poll indicated that fully 61% of the American public does not know that injury is the leading cause of death for those aged 1 to 34, and most believe that a trauma system is in place in every state. Almost two-thirds of the American public is confident of receiving the best medical care in the event of serious injury and would be seriously concerned if no trauma center were nearby. But only eight states have fully developed trauma systems, and most states have no federal funding or infrastructure in place for managing the aftermath of a natural disaster or terrorist event. These and other objective data reveal the mismatch between public perceptions and reality. Although almost 90% of Americans believe that state trauma systems and hospitals should have a coordinated trauma response, this has

Housing in China: State Governance, Market and Public Perception

Directory of Open Access Journals (Sweden)

Emile Kok-Kheng Yeoh

2017-04-01

Full Text Available Chinese house prices have been receiving huge coverage in both the domestic and the international media. Although the Chinese government has implemented many policies to control house prices, especially in the big cities, it is obvious that there is disequilibrium between demand for and supply of houses. Even though numerous housing policies have been put in place to overcome that, house prices in China are still rising. Many Chinese citizens from the low- and middle-incomes group find it difficult to purchase a house in the cities due to high house prices. This paper covers the current situation of the house prices in China, introduces the existing state of affairs about the Chinese housing market, explores a series of important reasons for high house prices, examines various public policies the Chinese government is using to control real estate, as well as reveals the citizens’ perceptions related to rising house prices. To gauge citizens’ perception of the current state of affairs in this regard, a questionnaire survey was conducted to gather information with a final sample of 256 respondents from more than ten cities of different tiers in the different regions of China.

[Current state of measures to deal with natural disasters at public universities].

Science.gov (United States)

Hirouchi, Tomoko; Tanka, Mamoru; Shimada, Ikuko; Yoshimoto, Yoshinobu; Sato, Atsushi

2012-03-01

The responsibility of a university after a large-scale, natural disaster is to secure the safety of students' and local residents' lives. The present study investigated the current state of measures at public universities to deal with natural disasters in coordination with the local community. A survey was administered at 77 public universities in Japan from March 25 to May 10, 2011. The survey included questions on the existence of local disaster evacuation sites, a disaster manual, disaster equipment storage, emergency drinking water, and food storage. A total of 51% of universities had designated local evacuation sites. Based on responses for the remaining questions, universities with and without the designated disaster response solutions accounted for 42% and 57%, respectively, for disaster manuals; 55% and 33%, respectively, for disaster equipment; 32% and 13%, respectively, for disaster drinking water storage; and 26% and 7%, respectively, for emergency food storage. A majority of public universities have not created disaster manuals, regardless of whether they have a local evacuation site. The survey results also indicated that most universities have no storage of disaster equipment or emergency supplies.

Public Health Departments

Data.gov (United States)

Department of Homeland Security — State and Local Public Health Departments in the United States Governmental public health departments are responsible for creating and maintaining conditions that...

The politics of technology and site location: impact of state interventionism on an Indian public sector firm

Directory of Open Access Journals (Sweden)

Dilip Subramanian

2013-11-01

Full Text Available Can an industrial organisation simultaneously fulfil economic and social functions, that is to say successfully reconcile its own priorities of optimal resource utilisation and productive efficiency with the larger objectives of social justice defined for it by public authorities? This is the central question this paper whose compass is restricted to the 1980s asks, and seeks to answer on the basis of a study of locational and technology choices at a big public sector manufacturing firm, Indian Telephone Industries. It will show how decisions pertaining both to the implantation of new state-owned factories and the sourcing of technology were shaped not by an economic rationale but a political one where employment generation took precedence over all other considerations. This was a consequence, on the one hand, of the paradigm of state-initiated industrial development embraced by India after Independence in 1947 and which held out the promise of future prosperity for the population at large; on the other, of the mode of governance prevailing in public enterprises where state interventionism rhymed with the complete loss of autonomy for managements. The paper concludes by pointing out that however justified the redistributive goals allocated to public enterprises from the standpoint of improving living standards, they proved highly detrimental to their efficient working as well as onerous for the exchequer.

Participation and environment: The realization of environmental public audiences in the United States, Quebec and Brazil

International Nuclear Information System (INIS)

Fischer de Lemos, Chelen

2001-01-01

This article examines three experiences accomplishment of environmental public hearings as mechanisms of society participation in discussion and decision-making concerning the environmental problems: the United States experience, the Quebec experience and the Brazil experience. The analysis focuses the most significant aspects of the citizen participation for the state environment management and effective resolution of the environmental problems

Job satisfaction among public health professionals working in public sector: a cross sectional study from Pakistan.

Science.gov (United States)

Kumar, Ramesh; Ahmed, Jamil; Shaikh, Babar Tasneem; Hafeez, Rehan; Hafeez, Assad

2013-01-09

Job satisfaction largely determines the productivity and efficiency of human resource for health. It literally depicts the extent to which professionals like or dislike their jobs. Job satisfaction is said to be linked with the employee's work environment, job responsibilities and powers and time pressure; the determinants which affect employee's organizational commitment and consequently the quality of services. The objective of the study was to determine the level of and factors influencing job satisfaction among public health professionals in the public sector. This was a cross sectional study conducted in Islamabad, Pakistan. Sample size was universal including 73 public health professionals, with postgraduate qualifications and working in government departments of Islamabad. A validated structured questionnaire was used to collect data from April to October 2011. Overall satisfaction rate was 41% only, while 45% were somewhat satisfied and 14% of professionals highly dissatisfied with their jobs. For those who were not satisfied, working environment, job description and time pressure were the major causes. Other factors influencing the level of satisfaction were low salaries, lack of training opportunities, improper supervision and inadequate financial rewards. Our study documented a relatively low level of overall satisfaction among workers in public sector health care organizations. Considering the factors responsible for this state of affairs, urgent and concrete strategies must be developed to address the concerns of public health professionals as they represent a highly sensitive domain of health system of Pakistan. Improving the overall work environment, review of job descriptions and better remuneration might bring about a positive change.

Hybrid diffusion-P3 equation in N-layered turbid media: steady-state domain.

Science.gov (United States)

Shi, Zhenzhi; Zhao, Huijuan; Xu, Kexin

2011-10-01

This paper discusses light propagation in N-layered turbid media. The hybrid diffusion-P3 equation is solved for an N-layered finite or infinite turbid medium in the steady-state domain for one point source using the extrapolated boundary condition. The Fourier transform formalism is applied to derive the analytical solutions of the fluence rate in Fourier space. Two inverse Fourier transform methods are developed to calculate the fluence rate in real space. In addition, the solutions of the hybrid diffusion-P3 equation are compared to the solutions of the diffusion equation and the Monte Carlo simulation. For the case of small absorption coefficients, the solutions of the N-layered diffusion equation and hybrid diffusion-P3 equation are almost equivalent and are in agreement with the Monte Carlo simulation. For the case of large absorption coefficients, the model of the hybrid diffusion-P3 equation is more precise than that of the diffusion equation. In conclusion, the model of the hybrid diffusion-P3 equation can replace the diffusion equation for modeling light propagation in the N-layered turbid media for a wide range of absorption coefficients.

A National Blessing: Debt and Public Credit in the Atlantic Foundation of the United States of America

Directory of Open Access Journals (Sweden)

Matteo Battistini

2013-07-01

Full Text Available In the premises, the author analyses how the different historiographical trends concerning the Atlantic world have reduced the centrality of the State, and recent researches which focused on the processes of State-building and on the financial revolutions between the Seventeenth and the Nineteenth centuries. Within this frame, the essay outlines an Atlantic history of the foundation of the U.S. through a reading of the Report on Public Credit (1782 of Robert Morris, Superintendent of Finances, and some writings of Alexander Hamilton, Secretary of the Treasury. The author argues that the institution of public debt and the foundation of the national bank constituted an adequate response not only to the need of State which characterized European history, but also to the capitalistic practices which marked European economies. The author underlines the continuity between the processes of State-building and the transition to capitalism in Europe and America in the age of the democratic revolutions.

PUBLIC MANAGEMENT AND ORGANIZATIONAL VALUES IN PUBLIC ADMINISTRATION OF EASTERN SLAVONIA

OpenAIRE

Ruza Brcic; Ivan Malbasic

2013-01-01

For decades public administration has been considered a public issue in its own right, or even a causal factor of public issues. It is perceived as an inert and inflexible system that operates in a way that neither its practices nor its effects are transparent. With the aim of enhancing the eff ectiveness of public administration attempts have been made to redefi ne the role of the state and reform public administration and public management in accordance with that new role of the state, whic...

Doing the Right Thing: Measuring Well-Being for Public Policy

Directory of Open Access Journals (Sweden)

Marie J. C. Forgeard

2011-01-01

Full Text Available

Many experts now recognize that income is not a measure that alone captures the wellbeing of individuals, and governments around the world are starting to rethink the ways in which they measure the welfare of their citizens. Wellbeing is best understood as a multifaceted phenomenon that can be assessed by measuring a wide array of subjective and objective constructs. This review summarizes the state of research on the various domains of wellbeing measured by psychologists and social scientists, and provides an overview of the main theoretical perspectives that integrate these domains. Among these theoretical perspectives, we highlight Well-being Theory, which decomposes the wellbeing construct into five domains: Positive emotion, Engagement, Relationships, Meaning, and Accomplishment (PERMA. We conclude by formulating recommendations for future research on the measurement of wellbeing. These recommendations include the need to combine both objective and subjective indicators, and the use of a dashboard approach to measurement. This approach conveys the multifaceted nature of wellbeing and will help policy-makers and citizens understand which domains of wellbeing should constitute priorities for public policy.

Public opinion about laws to prohibit weight discrimination in the United States.

Science.gov (United States)

Puhl, Rebecca M; Heuer, Chelsea A

2011-01-01

Weight discrimination is pervasive in American society and impairs quality of life for obese persons. With approximately two-thirds of Americans now overweight or obese, vast numbers of people are vulnerable to weight prejudice and its consequences. Currently, no laws exist to prohibit weight discrimination. This study conducted an online survey with a national sample of 1,001 adults (representing demographics of the United States) to examine public support for six potential legislative measures to prohibit weight discrimination in the United States. Results indicated substantial support (65% of men, 81% of women) for laws to prohibit weight discrimination in the workplace, especially for legal measures that would prohibit employers from refusing to hire, terminate, or deny promotion based on a person's body weight. Laws that proposed extending the same protections to obese persons as people with physical disabilities received the least support, suggesting that Americans may not be in favor of considering obesity as a disability. Findings also highlight specific predictors of support (related to sex, age, education, income, body weight, and political ideology). These findings can be used to inform policy makers in efforts to develop antidiscrimination laws. Such measures will rectify health disparities for overweight Americans and facilitate public health efforts to address obesity.

Domain switching in single-phase multiferroics

Science.gov (United States)

Jia, Tingting; Cheng, Zhenxiang; Zhao, Hongyang; Kimura, Hideo

2018-06-01

Multiferroics are a time-honoured research subject by reason for their tremendous application potential in the information industry, such as in multi-state information storage devices and new types of sensors. An outburst of studies on multiferroicity has been witnessed in the 21st century, although this field has a long research history since the 19th century. Multiferroicity has now become one of the hottest research topics in condensed matter physics and materials science. Numerous efforts have been made to investigate the cross-coupling phenomena among ferroic orders such as ferroelectricity, (anti-)ferromagnetism, and ferroelasticity, especially the coupling between electric and magnetic orderings that would account for the magnetoelectric (ME) effect in multiferroic materials. The magnetoelectric properties and coupling behavior of single phase multiferroics are dominated by their domain structures. It was also noted that, however, the multiferroic materials exhibit very complicated domain structures. Studies on domain structure characterization and domain switching are a crucial step in the exploration of approaches to the control and manipulation of magnetic (electric) properties using an electric (magnetic) field or other means. In this review, following a concise outline of our current basic knowledge on the magnetoelectric (ME) effect, we summarize some important research activities on domain switching in single-phase multiferroic materials in the form of single crystals and thin films, especially domain switching behavior involving strain and the related physics in the last decade. We also introduce recent developments in characterization techniques for domain structures of ferroelectric or multiferroic materials, which have significantly advanced our understanding of domain switching dynamics and interactions. The effects of a series of issues such as electric field, magnetic field, and stress effects on domain switching are been discussed as well. It

Peculiarities of activities of public administration subjects in the public finance

Directory of Open Access Journals (Sweden)

Світлана Миколаївна Клімова

2017-12-01

Full Text Available A comprehensive reform of public administration and public finances conducted in Ukraine to implement the Association Agreement between Ukraine and the EU requires a thorough research. Problems related to the functioning of public administration, investigated by V. Averyanov, M. Benio, T.Belozerskaya, S. Vitvitsky, D. Vlasenko, S. Gaiduchenko, N. Hnidyuk, O. Jafarova, A. Zelentsov, T. Karabin, T. Kolomoets. The subject of the study is public administration in the field of public finance. T. Karabin investigated the basic theory of public administration and singled out the following: 1 classical theory; 2 the theory of new public management; 3 the theory of public service. The wording of the "broad" and "narrow" understanding of public administration should be made taking into account that today the public administration in Ukraine in the narrow sense consists of: 1 the bodies of state executive power (the Cabinet of Ministers of Ukraine, central executive authorities, their territorial offices, local state administrations, etc.; 2 specialized public authorities (for example, the Accounting Chamber, the National Bank of Ukraine; 3 subjects of local self-government (village, settlement, city council, village, settlement, city mayor, executive bodies of village, settlement, city council, head of state, rayon and regional councils, representing common interests of territorial communities of villages, settlements, cities; organs of self-organization of the population . In the broad sense, non-state actors (both collective and individual should be included in the circle of subjects of the public administration of Ukraine, which delegates power and administrative powers, which are in continuous interaction with public authorities, performing the functions assigned to them. The complexity of public administration in our country is due to the variability of all elements of the system, the links between them and the environment in which the

Public scientific communication: reflections on the public and its participation forms

Directory of Open Access Journals (Sweden)

Peter Sekloča

2009-09-01

Full Text Available Scientific communication also pertains to the domain of society, where the formation of public opinion about science and technology is taking place. Concerning this process, two main points are exposed in the commentary. The first is a proposition on how the public as a social category may be conceptualized, and the second is the extent of the participation of members of the public in strengthening socialization and democratization practices in new, highly complex, contexts of scientific research. The public is conceptualized to include all citizens no matter their professional origin, including scientists, which promotes the idea of openness and equality of the public sphere where scientific issues are discussed. To be democratic in its practical-political setting, such a conception needs to deal with the problems of participation in a highly mediatized world, where not every member of the public could be included into scientific research. The author thus reflects on the mechanisms which would enable the formation of public forums where the trust of influential public actors as stakeholders of research can be tested.

[State of food and nutritional care in public hospitals of Ecuador].

Science.gov (United States)

Gallegos Espinosa, Sylvia; Nicolalde Cifuentes, Marcelo; Santana Porbén, Sergio

2014-10-03

The ELAN Ecuadorian Study of Hospital Malnutrition returned a malnutrition rate of 37.1% in public hospitals of Ecuador [Gallegos Espinosa S, Nicolalde Cifuentes M, Santana Porbén S; para el Grupo Ecuatoriano de Estudio de la Desnutrición Hospitalaria. State of malnutrition in hospitals of Ecuador. Nutr Hosp (España) 2014;30:425-35]. Hospital malnutrition could be the result of institutional cultural practices affecting the patient's nutritional status. To present the current state of food and nutritional care provided to patients assisted in public hospitals of Ecuador. The state of food and nutritional care provided to 5,355 patients assisted in 36 hospitals of 23 provinces of the country was documented by means of the Hospital Nutrition Survey (HNS), conducted as part of the ELAN Study. HNS recorded the completion of nutritional assessment exercises, the use of food-bymouth, fasting, use of oral nutritional supplements, and implementation and conduction of Artificial nutritional schemes (Enteral/Parenteral); respectively. Less than 0.1% of clinical charts had a diagnosis of malnutrition included in the list of the patient's health problems. Less than half of the patients had been measured and weighted on admission. Serum Albumin values and Total Lymphocytes Counts were annotated on admission in only 13.5% and 59.2% of the instances, respectively. Current weight value was registered in only 59.4% of the patients with length of stay ³ 15 days. An oral nutritional supplement was prescribed in just 3.5% of non-malnourished patients in which significant metabolic stress and/or reduced food intakes concurred. Although up to 10 different indications for use of Artificial nutrition were identified in the sample study, any of these techniques was administered to just 2.5% (median of observed percentages; range: 1.3 - 11.9%) of surveyed patients. Currently, nutritional status of hospitalized patient is not included within therapeutic goals, nutritional assessment

A systematic review of stated preference studies reporting public preferences for healthcare priority setting.

Science.gov (United States)

Whitty, Jennifer A; Lancsar, Emily; Rixon, Kylie; Golenko, Xanthe; Ratcliffe, Julie

2014-01-01

There is current interest in incorporating weights based on public preferences for health and healthcare into priority-setting decisions. The aim of this systematic review was to explore the extent to which public preferences and trade-offs for priority-setting criteria have been quantified, and to describe the study contexts and preference elicitation methods employed. A systematic review was performed in April 2013 to identify empirical studies eliciting the stated preferences of the public for the provision of healthcare in a priority-setting context. Studies are described in terms of (i) the stated preference approaches used, (ii) the priority-setting levels and contexts, and (iii) the criteria identified as important and their relative importance. Thirty-nine studies applying 40 elicitation methods reported in 41 papers met the inclusion criteria. The discrete choice experiment method was most commonly applied (n = 18, 45.0 %), but other approaches, including contingent valuation and the person trade-off, were also used. Studies prioritised health systems (n = 4, 10.2 %), policies/programmes/services/interventions (n = 16, 41.0 %), or patient groups (n = 19, 48.7 %). Studies generally confirmed the importance of a wide range of process, non-health and patient-related characteristics in priority setting in selected contexts, alongside health outcomes. However, inconsistencies were observed for the relative importance of some prioritisation criteria, suggesting context and/or elicitation approach matter. Overall, findings suggest caution in directly incorporating public preferences as weights for priority setting unless the methods used to elicit the weights can be shown to be appropriate and robust in the priority-setting context.

The African State and the role and nature of non-state sources of security in the Democratic Republic of Congo and South Africa

DEFF Research Database (Denmark)

Mandrup, Thomas

2012-01-01

use of violence as being the domain of the modern state, which as a natural consequence, delegitimises non-state providers of security. Legitimacy is, therefore, tied to the formal state. Th e international debate concerning the role of PMSCs has been split primarily into two segments. One argues...... to control confl icts has led to low-intensity confl icts (LIC), which can be witnessed, for instance, in Uganda, the Democratic Republic of Congo, Colombia and Sri Lanka (O’Brien, 1998, p. 80). Since the end of the Cold War it has been common for weak state rulers with formal state legitimacy...... security contractors have led, both historically and at the present day, to fi erce academic and public debate. As Sarah Percy argues, the anti-mercenary discourse has two basic elements. One focuses on the fact that mercenaries use force outside what is considered to be legitimate, authoritative control...

The BRCT domain is a phospho-protein binding domain.

Science.gov (United States)

Yu, Xiaochun; Chini, Claudia Christiano Silva; He, Miao; Mer, Georges; Chen, Junjie

2003-10-24

The carboxyl-terminal domain (BRCT) of the Breast Cancer Gene 1 (BRCA1) protein is an evolutionarily conserved module that exists in a large number of proteins from prokaryotes to eukaryotes. Although most BRCT domain-containing proteins participate in DNA-damage checkpoint or DNA-repair pathways, or both, the function of the BRCT domain is not fully understood. We show that the BRCA1 BRCT domain directly interacts with phosphorylated BRCA1-Associated Carboxyl-terminal Helicase (BACH1). This specific interaction between BRCA1 and phosphorylated BACH1 is cell cycle regulated and is required for DNA damage-induced checkpoint control during the transition from G2 to M phase of the cell cycle. Further, we show that two other BRCT domains interact with their respective physiological partners in a phosphorylation-dependent manner. Thirteen additional BRCT domains also preferentially bind phospho-peptides rather than nonphosphorylated control peptides. These data imply that the BRCT domain is a phospho-protein binding domain involved in cell cycle control.

Structured Literature Review of disruptive innovation theory within the digital domain

DEFF Research Database (Denmark)

Vesti, Helle; Nielsen, Christian; Rosenstand, Claus Andreas Foss

2017-01-01

The area of interest is disruption is the digital domain. The research questions are: How has the disruption and digital disruption literature developed over time? What is the research focus into disruption regarding the digital domain and how has this changed over time? Which methods are being...... utilized in research regarding disruption and digital disruption? Where are the key contributors to disruption in general and in digital disruption? Is there a future for digital disruption research? The method is a Structured Literature Review (SLR). The contribution is the results of an analysis of 95...... publications within the field of disruption in the digital domain and disruptive innovation theory in general. Works of twelve practitioners and 83 academics are investigated....

Multi-Domain SDN Survivability for Agricultural Wireless Sensor Networks.

Science.gov (United States)

Huang, Tao; Yan, Siyu; Yang, Fan; Liu, Jiang

2016-11-06

Wireless sensor networks (WSNs) have been widely applied in agriculture field; meanwhile, the advent of multi-domain software-defined networks (SDNs) have improved the wireless resource utilization rate and strengthened network management. In recent times, multi-domain SDNs have been applied to agricultural sensor networks, namely multi-domain software-defined wireless sensor networks (SDWSNs). However, when the SDNs controlling agriculture networks suddenly become unavailable, whether intra-domain or inter-domain, sensor network communication is abnormal because of the loss of control. Moreover, there are controller and switch info-updating problems even if the controller becomes available again. To resolve these problems, this paper proposes a new approach based on an Open vSwitch extension for multi-domain SDWSNs, which can enhance agriculture network survivability and stability. We achieved this by designing a connection-state mechanism, a communication mechanism on both L2 and L3, and an info-updating mechanism based on Open vSwitch. The experimental results show that, whether it is agricultural inter-domain or intra-domain during the controller failure period, the sensor switches can enter failure recovery mode as soon as possible so that the sensor network keeps a stable throughput, a short failure recovery time below 300 ms, and low packet loss. Further, the domain can smoothly control the domain network again once the controller becomes available. This approach based on an Open vSwitch extension can enhance the survivability and stability of multi-domain SDWSNs in precision agriculture.

Multi-Domain SDN Survivability for Agricultural Wireless Sensor Networks

Directory of Open Access Journals (Sweden)

Tao Huang