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Sample records for ptba exhibits structural

  1. Proton microbeam irradiation effects on PtBA polymer

    Indian Academy of Sciences (India)

    J Kamila; S Roy; K Bhattacharjee; B Rout; B N Dev; R Guico; J Wang; A W Haberl; P Ayyub; P V Satyam

    2006-04-01

    Proton beam lithography has made it possible to make various types of 3D-structures in polymers. Usually PMMA, SU-8, PS polymers have been used as resist materials for lithographic purpose. Microbeam irradiation effects on poly-tert-butyl-acrylate (PtBA) polymer using 2.0 MeV proton microbeam are reported. Preliminary results on pattern formation on PtBA are carried out as a function of fluence. After writing the pattern, a thin layer of Ge is deposited. Distribution of Ge in pristine and ion beam patterned surface of PtBA polymer is studied using the optical and secondary electron microscopic experimental methods.

  2. Suppression of slow capacitance relaxation phenomenon in Pt/Ba0.3Sr0.7TiO3/Pt thin film ferroelectric structures by annealing in oxygen atmosphere

    KAUST Repository

    Altynnikov, A. G.

    2014-01-27

    The impact of oxygen annealing on the switching time of ferroelectric thin film capacitor structures Pt/Ba0.3Sr0.7TiO3/Pt was investigated. The response of their capacitance on pulsed control voltages before and after annealing was experimentally measured. It was demonstrated that the annealing results in suppression of the capacitance slow relaxation processes and increase of the threshold control voltages. These structures can therefore be attractive for fabrication of fast acting microwave devices. © 2014 Author(s).

  3. Exhibition

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    China[Guangzheu] International Trade Fair for Home Textiles Date:March 18th- March 21st,2011 Venue:China Import and Export Fair Complex(Guangzhou,China) Organizers:China National Textile&Apparel Council China Foreign Trade Center(Group) China Home Textile Association China Foreign Trade Guangzhou Exhibition Corp.

  4. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    A Look of Hope Islam Mahmoud Sweity From 19 to 30 June 2017 CERN Meyrin, Main Building Islam Mahmoud Sweity Islam Mahmoud Sweity was born in 1997 at Beit Awwa, Palestine. She is currently following a course to get an Art diploma of Painting at the college of Fine Arts at An-Najah National University under the supervision of Esmat Al As'aad. Her portraits, landscapes and still life paintings are full of life and shining colours. Charged of emotional empathy they catch the attention of the viewer and are reminding us that life is beautiful and worth living in spite of all difficulties we have to go through. She participated in many exhibitions and has exposed her drawings in 2015 at CERN and in France in the framework of the exhibition "The Origin“, and in 2017 in the Former Yugoslav Republic of Macedonia, Palestina and Jordan. In this exhibition the oil paintings made in the past year will be presented. For more information : staff.association@cern.ch | T&eacu...

  5. Exhibition

    CERN Multimedia

    Staff Association

    2016-01-01

    Encounters Hanne Blitz From February 1st to 12th 2016 CERN Meyrin, Main Building What is our reaction to a first encounter with a tourist attraction? Contemporary Dutch painter Hanne Blitz captures visitors' responses to art and architecture, sweeping vistas and symbolic memorials. Encounters, a series of oil paintings curated specially for this CERN exhibition, depicts tourists visiting cultural highlights around the world. A thought-provoking journey not to be missed, and a tip of the hat to CERN's large Hadron Collider.

  6. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    Sintropie Flavio Pellegrini From 13 to 24 March 2017 CERN Meyrin, Main Building Energia imprigionata - Flavio Pellegrini. The exhibition is composed by eleven wood artworks with the expression of movement as theme. The artworks are the result of harmonics math applied to sculpture. The powerful black colour is dominated by the light source, generating reflexes and modulations. The result is a continuous variation of perspective visions. The works generate, at a first approach, an emotion of mystery and incomprehension, only a deeper contemplation lets one discover entangling and mutative details, evidencing the elegance of the lines and letting the meaning emerge. For more information : staff.association@cern.ch | Tél: 022 766 37 38

  7. Exhibition

    CERN Multimedia

    Staff Association

    2014-01-01

      Parallels vision Astronomical subjects which evoke extrasensory kinetic visions Alberto Di Fabio From 8 to 10 October, CERN Meyrin, Main Building In the framework of Italy@cern, the Staff Association presents Alberto Di Fabio. Di Fabio’s work is inspired by the fundamental laws of the physical world, as well as organic elements and their interrelation. His paintings and works on paper merge the worlds of art and science, depicting natural forms and biological structures in vivid colour and imaginative detail. For all additional information: staff.association@cern.ch | Tel: 022 767 28 19

  8. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    Le Point Isabelle Gailland Du 20 février au 3 mars 2017 CERN Meyrin, Bâtiment principal La Diagonale - Isabelle Gailland. Au départ, un toujours même point minuscule posé au centre de ce que la toile est un espace. Une réplique d'autres points, condensés, alignés, isolés, disséminés construiront dans leur extension, la ligne. Ces lignes, croisées, courbées, déviées, prolongées, seront la structure contenant et séparant la matière des couleurs. La rotation de chaque toile en cours d'exécution va offrir un accès illimité à la non-forme et à la forme. Le point final sera l'ouverture sur différents points de vue de ce que le point et la ligne sont devenus une représentation pour l'œil et l'im...

  9. A Social Network Model Exhibiting Tunable Overlapping Community Structure

    NARCIS (Netherlands)

    Liu, D.; Blenn, N.; Van Mieghem, P.F.A.

    2012-01-01

    Social networks, as well as many other real-world networks, exhibit overlapping community structure. In this paper, we present formulas which facilitate the computation for characterizing the overlapping community structure of networks. A hypergraph representation of networks with overlapping

  10. Transmission electron microscopy investigation of Pt/Ba0.7Sr0.3TiO3/Pt capacitors with different annealing processes

    NARCIS (Netherlands)

    Qin, Y.L.; Jia, C.L.; Liedtke, R.; Waser, R.; Urban, K.

    2003-01-01

    The effects of postannealing in oxygen ambient and forming gas atmosphere (FGA) on the microstructure and chemistry of Pt/Ba0.7Sr0.3TiO3 (BST)/Pt capacitors prepared by chemical solution deposition have been investigated by means of transmission electron microscopy. The as-deposited film layers of t

  11. Altered cytoskeletal structures in transformed cells exhibiting obviously metastatic capabilities

    Institute of Scientific and Technical Information of China (English)

    LINZHONGXIANG; WUBINGQUAN; 等

    1990-01-01

    Cytoskeletal changes in transformed cells (LM-51) eshibiting obviously metastatic capabilities were investigated by utilization of double-fluorescent labelling through combinations of:(1) tubulin indirect immunofluorescence plus Rhodamine-phalloidin staining of F-actins;(2) indirect immunofluorescent staining with α-actinin polyclonal-and vinculin monoclonal antibodies.The LM-51 cells which showed metastatic index of >50% were derived from lung metastasis in nude mice after subcutaneous inoculation of human highly metastatic tumor DNA transfected NIH3T3 cell transformants.The parent NIH3T3 cells exhibited well-organized microtubules,prominent stress fibers and adhesion plaques while their transformants showed remarkable cytoskeletal alterations:(1)reduced microtubules but increased MTOC fluorescence;(2)disrupted stress fibers and fewer adhesion plaques with their protein components redistributed in the cytoplasm;(3)Factin-and α-actinin/vinculin aggregates appeared in the cytoplasm.These aggregates were dot-like,varied in size(0.1-0.4μm) and number,located near the ventral surface of the cells.TPA-induced actin/vinculin bodies were studied too.Indications that actin and α-actinin/vinculin redistribution might be important alterations involved in the expression of metastatic capabilities of LM-51 transformed cells were discussed.

  12. A Novel Rational Design Method for Laminated Composite Structures Exhibiting Complex Geometrically Nonlinear Buckling Behaviour

    DEFF Research Database (Denmark)

    Lindgaard, Esben; Lund, Erik

    2012-01-01

    This paper presents a novel FEM-based approach for fiber angle optimal design of laminated composite structures exhibiting complicated nonlinear buckling behavior, thus enabling design of lighter and more cost-effective structures. The approach accounts for the geometrically nonlinear behavior...

  13. Exhibition of circular Bragg phenomenon by hyperbolic, dielectric, structurally chiral materials

    Science.gov (United States)

    Lakhtakia, Akhlesh

    2014-01-01

    The relative permittivity dyadic of a dielectric structurally chiral material (SCM) varies helicoidally along a fixed direction; in consequence, the SCM exhibits the circular Bragg phenomenon, which is the circular-polarization-selective reflection of light. The introduction of hyperbolicity in an SCM-by making either one or two but not all three eigenvalues of the relative permittivity dyadic acquire negative real parts-does not eliminate the circular Bragg phenomenon, but significantly alters the regime for its exhibition. Significantly wider circular-polarization-sensitive stopbands may be exhibited by hyperbolic SCMs in comparison to nonhyperbolic SCMs. Physical vapor deposition techniques appear to be suitable to fabricate hyperbolic SCMs.

  14. Exhibition of circular Bragg phenomenon by hyperbolic, dielectric, structurally chiral materials

    CERN Document Server

    Lakhtakia, Akhlesh

    2013-01-01

    The relative permittivity dyadic of a dielectric structurally chiral material (SCM) varies helicoidally along a fixed direction; in consequence, the SCM exhibits the circular Bragg phenomenon, which is the circular-polarization-selective reflection of light. The introduction of hyperbolicity in an SCM---by making either one or two but not all three eigenvalues of the relative permittivity dyadic acquire negative real parts---does not eliminate the circular Bragg phenomenon, but significantly alters the regime for its exhibition. Physical vapor deposition techniques appear to be suitable to fabricate hyperbolic SCMs.

  15. Tunable plasmon lensing in graphene-based structure exhibiting negative refraction

    OpenAIRE

    Zhong, Shifeng; Lu, Yanxin; Li, Chao; Xu, Haixia; Shi, Fenghua; Chen, Yihang

    2017-01-01

    We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provide the hyperbolic dispersion relations of the graphene plasmon, giving rise to the all-angle plasmonic negative refraction. Plasmon lensing induced from the negative refraction is...

  16. Exhibition of circular Bragg phenomenon by hyperbolic, dielectric, structurally chiral materials

    OpenAIRE

    Lakhtakia, Akhlesh

    2013-01-01

    The relative permittivity dyadic of a dielectric structurally chiral material (SCM) varies helicoidally along a fixed direction; in consequence, the SCM exhibits the circular Bragg phenomenon, which is the circular-polarization-selective reflection of light. The introduction of hyperbolicity in an SCM---by making either one or two but not all three eigenvalues of the relative permittivity dyadic acquire negative real parts---does not eliminate the circular Bragg phenomenon, but significantly ...

  17. Crystal structure studies of NADP+ dependent isocitrate dehydrogenase from Thermus thermophilus exhibiting a novel terminal domain.

    Science.gov (United States)

    Kumar, S M; Pampa, K J; Manjula, M; Abdoh, M M M; Kunishima, Naoki; Lokanath, N K

    2014-06-20

    NADP(+) dependent isocitrate dehydrogenase (IDH) is an enzyme catalyzing oxidative decarboxylation of isocitrate into oxalosuccinate (intermediate) and finally the product α-ketoglutarate. The crystal structure of Thermus thermophilus isocitrate dehydrogenase (TtIDH) ternary complex with citrate and cofactor NADP(+) was determined using X-ray diffraction method to a resolution of 1.80 Å. The overall fold of this protein was resolved into large domain, small domain and a clasp domain. The monomeric structure reveals a novel terminal domain involved in dimerization, very unique and novel domain when compared to other IDH's. And, small domain and clasp domain showing significant differences when compared to other IDH's of the same sub-family. The structure of TtIDH reveals the absence of helix at the clasp domain, which is mainly involved in oligomerization in other IDH's. Also, helices/beta sheets are absent in the small domain, when compared to other IDH's of the same sub family. The overall TtIDH structure exhibits closed conformation with catalytic triad residues, Tyr144-Asp248-Lys191 are conserved. Oligomerization of the protein is quantized using interface area and subunit-subunit interactions between protomers. Overall, the TtIDH structure with novel terminal domain may be categorized as a first structure of subfamily of type IV.

  18. Structure-Based Inhibitors Exhibit Differential Activities against Helicobacter pylori and Escherichia coli Undecaprenyl Pyrophosphate Synthases

    Directory of Open Access Journals (Sweden)

    Chih-Jung Kuo

    2008-01-01

    Full Text Available Helicobacter pylori colonizes the human gastric epithelium and causes diseases such as gastritis, peptic ulcers, and stomach cancer. Undecaprenyl pyrophosphate synthase (UPPS, which catalyzes consecutive condensation reactions of farnesyl pyrophosphate with eight isopentenyl pyrophosphate to form lipid carrier for bacterial peptidoglycan biosynthesis, represents a potential target for developing new antibiotics. In this study, we solved the crystal structure of H. pylori UPPS and performed virtual screening of inhibitors from a library of 58,635 compounds. Two hits were found to exhibit differential activities against Helicobacter pylori and Escherichia coli UPPS, giving the possibility of developing antibiotics specially targeting pathogenic H. pylori without killing the intestinal E. coli.

  19. Multiple scattering of polarized light in disordered media exhibiting short-range structural correlations

    Science.gov (United States)

    Vynck, Kevin; Pierrat, Romain; Carminati, Rémi

    2016-09-01

    We develop a model based on a multiple scattering theory to describe the diffusion of polarized light in disordered media exhibiting short-range structural correlations. Starting from exact expressions of the average field and the field spatial correlation function, we derive a radiative transfer equation for the polarization-resolved specific intensity that is valid for weak disorder and we solve it analytically in the diffusion limit. A decomposition of the specific intensity in terms of polarization eigenmodes reveals how structural correlations, represented via the standard anisotropic scattering parameter g , affect the diffusion of polarized light. More specifically, we find that propagation through each polarization eigenchannel is described by its own transport mean free path that depends on g in a specific and nontrivial way.

  20. Multiple scattering of polarized light in disordered media exhibiting short-range structural correlations

    CERN Document Server

    Vynck, Kevin; Carminati, Rémi

    2016-01-01

    We develop a model based on a multiple scattering theory to describe the diffusion of polarized light in disordered media exhibiting short-range structural correlations. Starting from exact expressions of the average field and the field spatial correlation function, we derive a radiative transfer equation for the polarization-resolved specific intensity that is valid for weak disorder and we solve it analytically in the diffusion limit. A decomposition of the specific intensity in terms of polarization eigenmodes reveals how structural correlations, represented via the standard anisotropic scattering parameter $g$, affect the diffusion of polarized light. More specifically, we find that propagation through each polarization eigenchannel is described by its own transport mean free path that depends on $g$ in a specific and non-trivial way.

  1. Synthesis, structural and electrochemical characterization of benzimidazole compounds exhibiting a smectic C liquid crystal phase

    Science.gov (United States)

    Wei, Bingzhuo; Tan, Shuai; Liang, Ting; Cao, Siyu; Wu, Yong

    2017-04-01

    Mesomorphic benzimidazole compounds were prepared from a biphenyl benzoate based precursor by substitution reaction of alkyl bromide with 2-mercaptobenzimidazole. Molecular structures of the benzimidazole compounds were characterized by nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR) spectroscopy and elemental analysis. Differential scanning calorimetry (DSC) measurements and polarizing optical microscopic (POM) observations revealed that the benzimidazole compounds exhibited a thermotropic smectic C (SC) phase. Temperature dependent X-ray diffraction (XRD) patterns suggested a tilted bilayer smectic structure in which intermolecular hydrogen bonds between benzimidazole moieties formed lamellar arrangement. Electrochemical impedance spectroscopy (EIS) characterization suggested that the SC phase favored anhydrous proton conduction of the benzimidazole compounds and the proton conductivities showed an Arrhenius temperature dependence.

  2. Tunable plasmon lensing in graphene-based structure exhibiting negative refraction

    Science.gov (United States)

    Zhong, Shifeng; Lu, Yanxin; Li, Chao; Xu, Haixia; Shi, Fenghua; Chen, Yihang

    2017-02-01

    We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provide the hyperbolic dispersion relations of the graphene plasmon, giving rise to the all-angle plasmonic negative refraction. Plasmon lensing induced from the negative refraction is observed. We show that the ultracompact graphene-based system can produce sub-diffraction-limited images with the resolution significant smaller than the wavelength of the incident terahertz wave. Moreover, by adjusting the Fermi energy of the graphene, the imaging performance of the proposed system can remain almost invariant for different frequencies. Our results may find applications in diverse fields such as subwavelength spatial light manipulation, biological imaging, and so forth.

  3. Tunable plasmon lensing in graphene-based structure exhibiting negative refraction

    Science.gov (United States)

    Zhong, Shifeng; Lu, Yanxin; Li, Chao; Xu, Haixia; Shi, Fenghua; Chen, Yihang

    2017-01-01

    We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provide the hyperbolic dispersion relations of the graphene plasmon, giving rise to the all-angle plasmonic negative refraction. Plasmon lensing induced from the negative refraction is observed. We show that the ultracompact graphene-based system can produce sub-diffraction-limited images with the resolution significant smaller than the wavelength of the incident terahertz wave. Moreover, by adjusting the Fermi energy of the graphene, the imaging performance of the proposed system can remain almost invariant for different frequencies. Our results may find applications in diverse fields such as subwavelength spatial light manipulation, biological imaging, and so forth. PMID:28150750

  4. HIV-1 Protease with 20 Mutations Exhibits Extreme Resistance to Clinical Inhibitors through Coordinated Structural Rearrangements

    Energy Technology Data Exchange (ETDEWEB)

    Agniswamy, Johnson; Shen, Chen-Hsiang; Aniana, Annie; Sayer, Jane M.; Louis, John M.; Weber, Irene T. (GSU); (NIH)

    2012-06-28

    The escape mutant of HIV-1 protease (PR) containing 20 mutations (PR20) undergoes efficient polyprotein processing even in the presence of clinical protease inhibitors (PIs). PR20 shows >3 orders of magnitude decreased affinity for PIs darunavir (DRV) and saquinavir (SQV) relative to PR. Crystal structures of PR20 crystallized with yttrium, substrate analogue p2-NC, DRV, and SQV reveal three distinct conformations of the flexible flaps and diminished interactions with inhibitors through the combination of multiple mutations. PR20 with yttrium at the active site exhibits widely separated flaps lacking the usual intersubunit contacts seen in other inhibitor-free dimers. Mutations of residues 35-37 in the hinge loop eliminate interactions and perturb the flap conformation. Crystals of PR20/p2-NC contain one uninhibited dimer with one very open flap and one closed flap and a second inhibitor-bound dimer in the closed form showing six fewer hydrogen bonds with the substrate analogue relative to wild-type PR. PR20 complexes with PIs exhibit expanded S2/S2' pockets and fewer PI interactions arising from coordinated effects of mutations throughout the structure, in agreement with the strikingly reduced affinity. In particular, insertion of the large aromatic side chains of L10F and L33F alters intersubunit interactions and widens the PI binding site through a network of hydrophobic contacts. The two very open conformations of PR20 as well as the expanded binding site of the inhibitor-bound closed form suggest possible approaches for modifying inhibitors to target extreme drug-resistant HIV.

  5. Why credit risk markets are predestined for exhibiting log-periodic power law structures

    Science.gov (United States)

    Wosnitza, Jan Henrik; Leker, Jens

    2014-01-01

    Recent research has established the existence of log-periodic power law (LPPL) patterns in financial institutions’ credit default swap (CDS) spreads. The main purpose of this paper is to clarify why credit risk markets are predestined for exhibiting LPPL structures. To this end, the credit risk prediction of two variants of logistic regression, i.e. polynomial logistic regression (PLR) and kernel logistic regression (KLR), are firstly compared to the standard logistic regression (SLR). In doing so, the question whether the performances of rating systems based on balance sheet ratios can be improved by nonlinear transformations of the explanatory variables is resolved. Building on the result that nonlinear balance sheet ratio transformations hardly improve the SLR’s predictive power in our case, we secondly compare the classification performance of a multivariate SLR to the discriminative powers of probabilities of default derived from three different capital market data, namely bonds, CDSs, and stocks. Benefiting from the prompt inclusion of relevant information, the capital market data in general and CDSs in particular increasingly outperform the SLR while approaching the time of the credit event. Due to the higher classification performances, it seems plausible for creditors to align their investment decisions with capital market-based default indicators, i.e., to imitate the aggregate opinion of the market participants. Since imitation is considered to be the source of LPPL structures in financial time series, it is highly plausible to scan CDS spread developments for LPPL patterns. By establishing LPPL patterns in governmental CDS spread trajectories of some European crisis countries, the LPPL’s application to credit risk markets is extended. This novel piece of evidence further strengthens the claim that credit risk markets are adequate breeding grounds for LPPL patterns.

  6. Ground-state characterizations of systems predicted to exhibit L11 or L13 crystal structures

    Science.gov (United States)

    Nelson, Lance J.; Hart, Gus L. W.; Curtarolo, Stefano

    2012-02-01

    Despite their geometric simplicity, the crystal structures L11 (CuPt) and L13 (CdPt3) do not appear as ground states experimentally, except in Cu-Pt. We investigate the possibility that these phases are ground states in other binary intermetallic systems, but overlooked experimentally. Via the synergy between high-throughput and cluster-expansion computational methods, we conduct a thorough search for systems that may exhibit these phases and calculate order-disorder transition temperatures when they are predicted. High-throughput calculations predict L11 ground states in the systems Ag-Pd, Ag-Pt, Cu-Pt, Pd-Pt, Li-Pd, Li-Pt, and L13 ground states in the systems Cd-Pt, Cu-Pt, Pd-Pt, Li-Pd, Li-Pt. Cluster expansions confirm the appearance of these ground states in some cases. In the other cases, cluster expansion predicts unsuspected derivative superstructures as ground states. The order-disorder transition temperatures for all L11/L13 ground states were found to be sufficiently high that their physical manifestation may be possible.

  7. Structural characterization of alkaline hydrogen peroxide pretreated grasses exhibiting diverse lignin phenotypes

    Science.gov (United States)

    2012-01-01

    Background For cellulosic biofuels processes, suitable characterization of the lignin remaining within the cell wall and correlation of quantified properties of lignin to cell wall polysaccharide enzymatic deconstruction is underrepresented in the literature. This is particularly true for grasses which represent a number of promising bioenergy feedstocks where quantification of grass lignins is particularly problematic due to the high fraction of p-hydroxycinnamates. The main focus of this work is to use grasses with a diverse range of lignin properties, and applying multiple lignin characterization platforms, attempt to correlate the differences in these lignin properties to the susceptibility to alkaline hydrogen peroxide (AHP) pretreatment and subsequent enzymatic deconstruction. Results We were able to determine that the enzymatic hydrolysis of cellulose to to glucose (i.e. digestibility) of four grasses with relatively diverse lignin phenotypes could be correlated to total lignin content and the content of p-hydroxycinnamates, while S/G ratios did not appear to contribute to the enzymatic digestibility or delignification. The lignins of the brown midrib corn stovers tested were significantly more condensed than a typical commercial corn stover and a significant finding was that pretreatment with alkaline hydrogen peroxide increases the fraction of lignins involved in condensed linkages from 88–95% to ~99% for all the corn stovers tested, which is much more than has been reported in the literature for other pretreatments. This indicates significant scission of β-O-4 bonds by pretreatment and/or induction of lignin condensation reactions. The S/G ratios in grasses determined by analytical pyrolysis are significantly lower than values obtained using either thioacidolysis or 2DHSQC NMR due to presumed interference by ferulates. Conclusions It was found that grass cell wall polysaccharide hydrolysis by cellulolytic enzymes for grasses exhibiting a diversity of

  8. Structural characterization of alkaline hydrogen peroxide pretreated grasses exhibiting diverse lignin phenotypes

    Directory of Open Access Journals (Sweden)

    Li Muyang

    2012-06-01

    exhibiting a diversity of lignin structures and compositions could be linked to quantifiable changes in the composition of the cell wall and properties of the lignin including apparent content of the p-hydroxycinnamates while the limitations of S/G estimation in grasses is highlighted.

  9. Crystal structures and inhibitor binding properties of plant class V chitinases: the cycad enzyme exhibits unique structural and functional features.

    Science.gov (United States)

    Umemoto, Naoyuki; Kanda, Yuka; Ohnuma, Takayuki; Osawa, Takuo; Numata, Tomoyuki; Sakuda, Shohei; Taira, Toki; Fukamizo, Tamo

    2015-04-01

    A class V (glycoside hydrolase family 18) chitinase from the cycad Cycas revoluta (CrChiA) is a plant chitinase that has been reported to possess efficient transglycosylation (TG) activity. We solved the crystal structure of CrChiA, and compared it with those of class V chitinases from Nicotiana tabacum (NtChiV) and Arabidopsis thaliana (AtChiC), which do not efficiently catalyze the TG reaction. All three chitinases had a similar (α/β)8 barrel fold with an (α + β) insertion domain. In the acceptor binding site (+1, +2 and +3) of CrChiA, the Trp168 side chain was found to stack face-to-face with the +3 sugar. However, this interaction was not found in the identical regions of NtChiV and AtChiC. In the DxDxE motif, which is essential for catalysis, the carboxyl group of the middle Asp (Asp117) was always oriented toward the catalytic acid Glu119 in CrChiA, whereas the corresponding Asp in NtChiV and AtChiC was oriented toward the first Asp. These structural features of CrChiA appear to be responsible for the efficient TG activity. When binding of the inhibitor allosamidin was evaluated using isothermal titration calorimetry, the changes in binding free energy of the three chitinases were found to be similar to each other, i.e. between -9.5 and -9.8 kcal mol(-1) . However, solvation and conformational entropy changes in CrChiA were markedly different from those in NtChiV and AtChiC, but similar to those of chitinase A from Serratia marcescens (SmChiA), which also exhibits significant TG activity. These results provide insight into the molecular mechanism underlying the TG reaction and the molecular evolution from bacterial chitinases to plant class V chitinases.

  10. Preparation of intercalated polyaniline/clay nanocomposite and its exfoliation exhibiting dendritic structure

    Indian Academy of Sciences (India)

    N Srivastava; Y Singh; R A Singh

    2011-07-01

    Intercalated composite of polyaniline and clay has been reported. The composite was prepared by in situ polymerization of aniline within the layers of `illite’ clay. The composite was characterized for its structural, spectral, and microscopic properties. At higher level of loading the layered structure of composite breaks forming exfoliated composite, revealing well-defined nanosized dendritic morphology of polyaniline.

  11. An International Symposium and Exhibition on Active Materials and Adaptive Structures.

    Science.gov (United States)

    2007-11-02

    Quantum Consultants, Inc. Implementing Smart Composites: Organizational/Environmental Issues 236 M. Martin, Michigan State University Activities of the...R. Measures, M. LeBlanc, K. McEwen, K. Shankar , R. Tennyson, University of Toronto Institute for Aerospace Studies Micro-Damage Analysis with...Ceramic Actuators 301 A. P. Ritter, A. Bailey, F. Poppe, N. Shankar & B. Rawal, Martin Marietta Smart Structural Composites with Inherent Sensing

  12. Functionally Distinct Tendons From Elastin Haploinsufficient Mice Exhibit Mild Stiffening and Tendon-Specific Structural Alteration.

    Science.gov (United States)

    Eekhoff, Jeremy D; Fang, Fei; Kahan, Lindsey G; Espinosa, Gabriela; Cocciolone, Austin J; Wagenseil, Jessica E; Mecham, Robert P; Lake, Spencer P

    2017-11-01

    Elastic fibers are present in low quantities in tendon, where they are located both within fascicles near tenocytes and more broadly in the interfascicular matrix (IFM). While elastic fibers have long been known to be significant in the mechanics of elastin-rich tissue (i.e., vasculature, skin, lungs), recent studies have suggested a mechanical role for elastic fibers in tendons that is dependent on specific tendon function. However, the exact contribution of elastin to properties of different types of tendons (e.g., positional, energy-storing) remains unknown. Therefore, this study purposed to evaluate the role of elastin in the mechanical properties and collagen alignment of functionally distinct supraspinatus tendons (SSTs) and Achilles tendons (ATs) from elastin haploinsufficient (HET) and wild type (WT) mice. Despite the significant decrease in elastin in HET tendons, a slight increase in linear stiffness of both tendons was the only significant mechanical effect of elastin haploinsufficiency. Additionally, there were significant changes in collagen nanostructure and subtle alteration to collagen alignment in the AT but not the SST. Hence, elastin may play only a minor role in tendon mechanical properties. Alternatively, larger changes to tendon mechanics may have been mitigated by developmental compensation of HET tendons and/or the role of elastic fibers may be less prominent in smaller mouse tendons compared to the larger bovine and human tendons evaluated in previous studies. Further research will be necessary to fully elucidate the influence of various elastic fiber components on structure-function relationships in functionally distinct tendons.

  13. Exhibit Engineering

    DEFF Research Database (Denmark)

    Mortensen, Marianne Foss

    ) a synthesis of the findings from the first two studies with findings from the literature to generate two types of results: a coherent series of suggestions for a design iteration of the studied exhibit as well as a more general normative model for exhibit engineering. Finally, another perspective...

  14. Human Exhibitions

    DEFF Research Database (Denmark)

    Andreassen, Rikke

    From 1870s to 1910s, more than 50 exhibitions of so-called exotic people took place in Denmark. Here large numbers of people of Asian and African origin were exhibited for the entertainment and ‘education’ of a mass audience. Several of these exhibitions took place in Copenhagen Zoo. Here different...... light on the staging of exhibitions, the daily life of the exhibitees, the wider connections between shows across Europe and the thinking of the time on matters of race, science, gender and sexuality. A window onto contemporary racial understandings, the book presents interviews with the descendants...... of displayed people, connecting the attitudes and science of the past with both our (continued) modern fascination with ‘the exotic’, and contemporary language and popular culture. As such, it will be of interest to scholars of sociology, anthropology and history working in the areas of gender and sexuality...

  15. Crystal structure studies of NADP{sup +} dependent isocitrate dehydrogenase from Thermus thermophilus exhibiting a novel terminal domain

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, S.M. [Department of Studies in Physics, University of Mysore, Mysore 570 006 (India); Pampa, K.J. [Department of Studies in Microbiology, University of Mysore, Mysore 570 006 (India); Manjula, M. [Department of Studies in Physics, University of Mysore, Mysore 570 006 (India); Abdoh, M.M.M. [Department of Physics, Faculty of Science, An-Najah National University, Nablus, West Bank, Palestine (Country Unknown); Kunishima, Naoki [Advanced Protein Crystallography Research Group, RIKEN SPring-8 Center, Harima Institute, Hyogo 679-5148 (Japan); Lokanath, N.K., E-mail: lokanath@physics.uni-mysore.ac.in [Department of Studies in Physics, University of Mysore, Mysore 570 006 (India)

    2014-06-20

    Highlights: • We determined the structure of isocitrate dehydrogenase with citrate and cofactor. • The structure reveals a unique novel terminal domain involved in dimerization. • Clasp domain shows significant difference, and catalytic residues are conserved. • Oligomerization of the enzyme is quantized with subunit-subunit interactions. • Novel domain of this enzyme is classified as subfamily of the type IV. - Abstract: NADP{sup +} dependent isocitrate dehydrogenase (IDH) is an enzyme catalyzing oxidative decarboxylation of isocitrate into oxalosuccinate (intermediate) and finally the product α-ketoglutarate. The crystal structure of Thermus thermophilus isocitrate dehydrogenase (TtIDH) ternary complex with citrate and cofactor NADP{sup +} was determined using X-ray diffraction method to a resolution of 1.80 Å. The overall fold of this protein was resolved into large domain, small domain and a clasp domain. The monomeric structure reveals a novel terminal domain involved in dimerization, very unique and novel domain when compared to other IDH’s. And, small domain and clasp domain showing significant differences when compared to other IDH’s of the same sub-family. The structure of TtIDH reveals the absence of helix at the clasp domain, which is mainly involved in oligomerization in other IDH’s. Also, helices/beta sheets are absent in the small domain, when compared to other IDH’s of the same sub family. The overall TtIDH structure exhibits closed conformation with catalytic triad residues, Tyr144-Asp248-Lys191 are conserved. Oligomerization of the protein is quantized using interface area and subunit–subunit interactions between protomers. Overall, the TtIDH structure with novel terminal domain may be categorized as a first structure of subfamily of type IV.

  16. The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.

    Science.gov (United States)

    Adams, Cassandra J; Pike, Ashley C W; Maniam, Sandra; Sharpe, Timothy D; Coutts, Amanda S; Knapp, Stefan; La Thangue, Nicholas B; Bullock, Alex N

    2012-03-01

    Activation of p53 target genes for tumor suppression depends on the stress-specific regulation of transcriptional coactivator complexes. Strap (stress-responsive activator of p300) is activated upon DNA damage by ataxia telangiectasia mutated (ATM) and Chk2 kinases and is a key regulator of the p53 response. In addition to antagonizing Mdm2, Strap facilitates the recruitment of p53 coactivators, including JMY and p300. Strap is a predicted TPR-repeat protein, but shows only limited sequence identity with any protein of known structure. To address this and to elucidate the molecular mechanism of Strap activity we determined the crystal structure of the full-length protein at 2.05 Å resolution. The structure of Strap reveals an atypical six tetratricopeptide repeat (TPR) protein that also contains an unexpected oligonucleotide/oligosaccharide-binding (OB)-fold domain. This previously unseen domain organization provides an extended superhelical scaffold allowing for protein-protein as well as protein-DNA interaction. We show that both of the TPR and OB-fold domains localize to the chromatin of p53 target genes and exhibit intrinsic regulatory activity necessary for the Strap-dependent p53 response.

  17. Development of a Cell-penetrating Peptide that Exhibits Responsive Changes in its Secondary Structure in the Cellular Environment

    Science.gov (United States)

    Yamashita, Hiroko; Kato, Takuma; Oba, Makoto; Misawa, Takashi; Hattori, Takayuki; Ohoka, Nobumichi; Tanaka, Masakazu; Naito, Mikihiko; Kurihara, Masaaki; Demizu, Yosuke

    2016-01-01

    Cell-penetrating peptides (CPP) are received a lot of attention as an intracellular delivery tool for hydrophilic molecules such as drugs, proteins, and DNAs. We designed and synthesized nona-arginine analogues 1–5 [FAM-β-Ala-(l-Arg-l-Arg-l-Pro)3-(Gly)3-NH2 (1), FAM-β-Ala-(l-Arg-l-Arg-l-ProNH2)3-(Gly)3-NH2 (2), FAM-β-Ala-(l-Arg-l-Arg-l-ProGu)3-(Gly)3-NH2 (3), FAM-β-Ala-(l-Arg)2-(l-ProGu)2-(l-Arg)4-l-ProGu-(Gly)3-NH2 (4), and FAM-β-Ala-(l-Arg)6-(l-ProGu)3-(Gly)3-NH2 (5)] containing l-proline (l-Pro) or cationic proline derivatives (l-ProNH2 and l-ProGu), and investigated their cell-penetrating abilities. Interestingly, only peptide 3 having the side-chain guanidinyl l-ProGu exhibited a secondary structural change in cellular environment. Specifically, peptide 3 formed a random structure in hydrophilic conditions, whereas it formed a helical structure under amphipathic conditions. Furthermore, during cellular permeability tests, peptide 3 demonstrated greater cell-penetrating activity than other peptides and effectively transported plasmid DNA into HeLa cells. Thus, l-ProGu-containing peptide 3 may be a useful candidate as a gene delivery carrier. PMID:27609319

  18. Exhibit Engineering

    DEFF Research Database (Denmark)

    Mortensen, Marianne Foss

    of tools and processes to guide the design of educational science exhibits. The guiding paradigm for this development is design-based research, which is characterised by an iterative cycle of design, enactment, and analysis. In the design phase, an educational intervention is planned and carried out based...... on a hypothesised learning process and the means of supporting it. In the enactment phase, the educational intervention is implemented (i.e. the planned lesson is taught, or the museum exhibit is opened to the public). Finally, the analysis phase establishes causality between emergent characteristics...... of the learning outcomes and the design characteristics of the intervention. The analysis process can yield two types of outcomes: Suggestions for the refinement of the specific design in question, and “humble” theory, which is theory that can guide the design of a category of educational interventions...

  19. Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Ying-Chuan; Perryman, Alexander L.; Olson, Arthur J.; Torbett, Bruce E.; Elder, John H.; Stout, C. David, E-mail: dave@scripps.edu [The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (United States)

    2011-06-01

    Crystal structures of the 6s-98S FIV protease chimera with darunavir and lopinavir bound have been determined at 1.7 and 1.8 Å resolution, respectively. A chimeric feline immunodeficiency virus (FIV) protease (PR) has been engineered that supports infectivity but confers sensitivity to the human immunodeficiency virus (HIV) PR inhibitors darunavir (DRV) and lopinavir (LPV). The 6s-98S PR has five replacements mimicking homologous residues in HIV PR and a sixth which mutated from Pro to Ser during selection. Crystal structures of the 6s-98S FIV PR chimera with DRV and LPV bound have been determined at 1.7 and 1.8 Å resolution, respectively. The structures reveal the role of a flexible 90s loop and residue 98 in supporting Gag processing and infectivity and the roles of residue 37 in the active site and residues 55, 57 and 59 in the flap in conferring the ability to specifically recognize HIV PR drugs. Specifically, Ile37Val preserves tertiary structure but prevents steric clashes with DRV and LPV. Asn55Met and Val59Ile induce a distinct kink in the flap and a new hydrogen bond to DRV. Ile98Pro→Ser and Pro100Asn increase 90s loop flexibility, Gln99Val contributes hydrophobic contacts to DRV and LPV, and Pro100Asn forms compensatory hydrogen bonds. The chimeric PR exhibits a comparable number of hydrogen bonds, electrostatic interactions and hydrophobic contacts with DRV and LPV as in the corresponding HIV PR complexes, consistent with IC{sub 50} values in the nanomolar range.

  20. Investigations of surface structural, dynamical, and magnetic properties of systems exhibiting multiferroicity, and topological phases by helium scattering spectroscopies

    Energy Technology Data Exchange (ETDEWEB)

    El-Batanouny, Maged

    2015-08-03

    We propose to investigate the surface structural, dynamics and magnetic properties of the novel class of topological insulator crystals, as well as crystals that exhibit multiferroicity, magnetoelectricity and thermoelectricity. Topological insulators (TIs) are a new class of insulators in which a bulk gap for electronic excitations is generated because of the strong spin-orbit coupling inherent to these systems. These materials are distinguished from ordinary insulators by the presence of gapless metallic surface states, resembling chiral edge modes in quantum Hall systems, but with unconventional spin textures. These exotic metallic states are formed by topological conditions that also render the electrons travelling on such surfaces insensitive to scattering by impurities. The electronic quasi-particles populating the topological surface state are Dirac fermions; they have a linear dispersion and thus are massless just like photons. We propose to investigate the interaction of these massless Dirac fermions with the massive lattice in the newly discovered crystals, Bi2Se3, Bi2Te3 and Sb2Te3. We shall use inelastic helium beam scattering from surfaces to search for related signatures in surface phonon dispersions mappings that cover the entire surface Brillouin zone of these materials. Our recent investigations of the (001) surface of the multiferroic crystals (Li/Na)Cu2O2 revealed an anomalous surface structural behavior where surface Cu$^{2+}$ row rise above the surface plane as the crystal was cooled. Subsequent worming revealed the onset of a thermally activated incommensurate surface phase, driven by the elevated rows. We are currently investigating the structure of the magnetic phases in these quasi-one-dimensional magnetic rows. Multiferroics are excellent candidates for large magnetoelectric response. We propose to extend this investigation to the class of delafossites which are also multiferroics and have been investigated as good candidates for

  1. Two spin-peierls-like compounds exhibiting divergent structural features, lattice compression, and expansion in the low- temperature phase.

    Science.gov (United States)

    Tian, Zhengfang; Duan, Haibao; Ren, Xiaoming; Lu, Changsheng; Li, Yizhi; Song, You; Zhu, Huizhen; Meng, Qingjin

    2009-06-18

    Two quasi-one-dimensional (quasi-1D) compounds, [4'-CH(3)Bz-4-RPy][Ni(mnt)(2)] (mnt(2-) = maleonitriledithiolate), where 4'-CH(3)Bz-4-RPy(+) = 1-(4'-methylbenzyl)pyridinium (denoted as compound 1) and 1-(4'-methylbenzyl)-4-aminopyridinium (denoted as compound 2), show a spin-Peierls-like transition with T(C) approximately 182 K for 1 and T(C) approximately 155 K for 2. The enthalpy changes for the transition are estimated to be DeltaH = 316.6 J.mol(-1) for 1 and 1082.1 J.mol(-1) for 2. From fits to the magnetic susceptibility, the magnetic exchange constants in the gapless state are calculated to be J = 166(2) K with g = 2.020(23) for 1 versus J = 42(0) K with g = 2.056(5) for 2. In the high-temperature (HT) phase, 1 and 2 are isostructural and crystallize in the monoclinic space group P2(1)/c. The nonmagnetic cations and paramagnetic anions form segregated columns with regular anionic and cationic stacks. In the low-temperature (LT) phase, the crystals of the two compounds undergo a transformation to the triclinic space group P-1, and both anionic and cationic stacks dimerize. In the transformation from the HT to LT phases, the two compounds exhibit divergent structural features, with lattice compression for 1 but lattice expansion for 2, due to intermolecular slippage. Combined with our previous studies, it is also noted that the transition temperature, T(C), is qualitatively related to the cell volume in the HT phase for the series of compounds [1-(4'-R-benzylpyridinium][Ni(mnt)(2)] (where R represents the substituent). When there is a single substituent in the para position of benzene, giving a larger cell volume, the transition temperature increases.

  2. Crystal structures of a poplar thioredoxin peroxidase that exhibits the structure of glutathione peroxidases: insights into redox-driven conformational changes.

    Science.gov (United States)

    Koh, Cha San; Didierjean, Claude; Navrot, Nicolas; Panjikar, Santosh; Mulliert, Guillermo; Rouhier, Nicolas; Jacquot, Jean-Pierre; Aubry, André; Shawkataly, Omar; Corbier, Catherine

    2007-07-13

    Glutathione peroxidases (GPXs) are a group of enzymes that regulate the levels of reactive oxygen species in cells and tissues, and protect them against oxidative damage. Contrary to most of their counterparts in animal cells, the higher plant GPX homologues identified so far possess cysteine instead of selenocysteine in their active site. Interestingly, the plant GPXs are not dependent on glutathione but rather on thioredoxin as their in vitro electron donor. We have determined the crystal structures of the reduced and oxidized form of Populus trichocarpaxdeltoides GPX5 (PtGPX5), using a selenomethionine derivative. PtGPX5 exhibits an overall structure similar to that of the known animal GPXs. PtGPX5 crystallized in the assumed physiological dimeric form, displaying a pseudo ten-stranded beta sheet core. Comparison of both redox structures indicates that a drastic conformational change is necessary to bring the two distant cysteine residues together to form an intramolecular disulfide bond. In addition, a computer model of a complex of PtGPX5 and its in vitro recycling partner thioredoxin h1 is proposed on the basis of the crystal packing of the oxidized form enzyme. A possible role of PtGPX5 as a heavy-metal sink is also discussed.

  3. Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure

    Energy Technology Data Exchange (ETDEWEB)

    Longenecker, Kenton L.; Stamper, Geoffrey F.; Hajduk, Philip J.; Fry, Elizabeth H.; Jakob, Clarissa G.; Harlan, John E.; Edalji, Rohinton; Bartley, Diane M.; Walter, Karl A.; Solomon, Larry R.; Holzman, Thomas F.; Gu, Yu Gui; Lerner, Claude G.; Beutel, Bruce A.; Stoll, Vincent S. (Abbott)

    2010-07-19

    In a broad genomics analysis to find novel protein targets for antibiotic discovery, MurF was identified as an essential gene product for Streptococcus pneumonia that catalyzes a critical reaction in the biosynthesis of the peptidoglycan in the formation of the cell wall. Lacking close relatives in mammalian biology, MurF presents attractive characteristics as a potential drug target. Initial screening of the Abbott small-molecule compound collection identified several compounds for further validation as pharmaceutical leads. Here we report the integrated efforts of NMR and X-ray crystallography, which reveal the multidomain structure of a MurF-inhibitor complex in a compact conformation that differs dramatically from related structures. The lead molecule is bound in the substrate-binding region and induces domain closure, suggestive of the domain arrangement for the as yet unobserved transition state conformation for MurF enzymes. The results form a basis for directed optimization of the compound lead by structure-based design to explore the suitability of MurF as a pharmaceutical target.

  4. The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.

    Science.gov (United States)

    Shen, Betty W; Lambert, Abigail; Walker, Bradley C; Stoddard, Barry L; Kaiser, Brett K

    2016-01-16

    LAGLIDADG homing endonucleases ("meganucleases") are highly specific DNA cleaving enzymes that are used for genome engineering. Like other enzymes that act on DNA targets, meganucleases often display binding affinities and cleavage activities that are dominated by one protein domain. To decipher the underlying mechanism of asymmetric DNA recognition and catalysis, we identified and characterized a new monomeric meganuclease (I-SmaMI), which belongs to a superfamily of homologous enzymes that recognize divergent DNA sequences. We solved a series of crystal structures of the enzyme-DNA complex representing a progression of sequential reaction states, and we compared the structural rearrangements and surface potential distributions within each protein domain against their relative contribution to binding affinity. We then determined the effects of equivalent point mutations in each of the two enzyme active sites to determine whether asymmetry in DNA recognition is translated into corresponding asymmetry in DNA cleavage activity. These experiments demonstrate the structural basis for "dominance" by one protein domain over the other and provide insights into this enzyme's conformational switch from a nonspecific search mode to a more specific recognition mode.

  5. Crystal structures of human group-VIIA phospholipase A2 inhibited by organophosphorus nerve agents exhibit non-aged complexes

    Energy Technology Data Exchange (ETDEWEB)

    Samanta, Uttamkumar; Kirby, Stephen D.; Srinivasan, Prabhavathi; Cerasoli, Douglas M.; Bahnson, Brian J.; (Delaware); (USAMRIID)

    2009-09-02

    The enzyme group-VIIA phospholipase A2 (gVIIA-PLA2) is bound to lipoproteins in human blood and hydrolyzes the ester bond at the sn-2 position of phospholipid substrates with a short sn-2 chain. The enzyme belongs to a serine hydrolase superfamily of enzymes, which react with organophosphorus (OP) nerve agents. OPs ultimately exert their toxicity by inhibiting human acetycholinesterase at nerve synapses, but may additionally have detrimental effects through inhibition of other serine hydrolases. We have solved the crystal structures of gVIIA-PLA2 following inhibition with the OPs diisopropylfluorophosphate, sarin, soman and tabun. The sarin and soman complexes displayed a racemic mix of P{sub R} and P{sub S} stereoisomers at the P-chiral center. The tabun complex displayed only the P{sub R} stereoisomer in the crystal. In all cases, the crystal structures contained intact OP adducts that had not aged. Aging refers to a secondary process OP complexes can go through, which dealkylates the nerve agent adduct and results in a form that is highly resistant to either spontaneous or oxime-mediated reactivation. Non-aged OP complexes of the enzyme were corroborated by trypsin digest and matrix-assisted laser desorption ionization mass spectrometry of OP-enzyme complexes. The lack of stereoselectivity of sarin reaction was confirmed by gas chromatography/mass spectrometry using a chiral column to separate and quantitate the unbound stereoisomers of sarin following incubation with enzyme. The structural details and characterization of nascent reactivity of several toxic nerve agents is discussed with a long-term goal of developing gVIIA-PLA2 as a catalytic bioscavenger of OP nerve agents.

  6. Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil.

    Science.gov (United States)

    Chung, Min-Yu; Woo, Hyunjoon; Kim, Juyeon; Kong, Daecheol; Choi, Hee-Don; Choi, In-Wook; Kim, In-Hwan; Noh, Sang K; Kim, Byung Hee

    2017-03-01

    The positional distribution pattern of fatty acids (FAs) in the triacylglycerols (TAGs) affects intestinal absorption of these FAs. The aim of this study was to compare lymphatic absorption of pinolenic acid (PLA) present in structured pinolenic TAG (SPT) where PLA was evenly distributed on the glycerol backbone, with absorption of pine nut oil (PNO) where PLA was predominantly positioned at the sn-3 position. SPT was prepared via the nonspecific lipase-catalyzed esterification of glycerol with free FA obtained from PNO. Lymphatic absorption of PLA from PNO and from SPT was compared in a rat model of lymphatic cannulation. Significantly (P PNO (26.2 ± 0.6% dose), thereby indicating that PLA present in SPT has a greater capacity for lymphatic absorption than PLA from PNO.

  7. Changes in magnetic domain structure during twin boundary motion in single crystal Ni-Mn-Ga exhibiting magnetic shape memory effect

    Science.gov (United States)

    Kopecký, V.; Fekete, L.; Perevertov, O.; Heczko, O.

    2016-05-01

    The complexity of Ni-Mn-Ga single crystal originates from the interplay between ferromagnetic domain structure and ferroelastic twinned microstructure. Magnetic domain structure in the vicinity of single twin boundary was studied using magneto-optical indicator film and magnetic force microscopy technique. The single twin boundary of Type I was formed mechanically and an initial magnetization state in both variants were restored by local application of magnetic field (≈40 kA/m). The differently oriented variants exhibited either stripe or labyrinth magnetic domain pattern in agreement with the uniaxial magnetocrystalline anisotropy of the martensite. The twin boundary was then moved by compressive or tensile stress. The passage of the boundary resulted in the formation of granular or rake domains, respectively. Additionally, the specific magnetic domains pattern projected by twin boundary gradually vanished during twin boundary motion.

  8. Changes in magnetic domain structure during twin boundary motion in single crystal Ni-Mn-Ga exhibiting magnetic shape memory effect

    Directory of Open Access Journals (Sweden)

    V. Kopecký

    2016-05-01

    Full Text Available The complexity of Ni-Mn-Ga single crystal originates from the interplay between ferromagnetic domain structure and ferroelastic twinned microstructure. Magnetic domain structure in the vicinity of single twin boundary was studied using magneto-optical indicator film and magnetic force microscopy technique. The single twin boundary of Type I was formed mechanically and an initial magnetization state in both variants were restored by local application of magnetic field (≈40 kA/m. The differently oriented variants exhibited either stripe or labyrinth magnetic domain pattern in agreement with the uniaxial magnetocrystalline anisotropy of the martensite. The twin boundary was then moved by compressive or tensile stress. The passage of the boundary resulted in the formation of granular or rake domains, respectively. Additionally, the specific magnetic domains pattern projected by twin boundary gradually vanished during twin boundary motion.

  9. Parallel Exhibits: Combining Physical and Virtual Exhibits

    NARCIS (Netherlands)

    L. Lischke; T. Dingler; S. Schneegaß; A. Schmidt; M. van der Vaart; P. Wozniak

    2014-01-01

    People have a special fascination for original physical objects, their texture, and visible history. However, the digitization of exhibits and the use of these data is a current challenge for museums. We believe that museums need to capitalize on the affordances of physical exhibits to help users na

  10. New series of asymmetrically substituted Bis(1,2-dithiolato)-nickel(III) complexes exhibiting near IR absorption and structural diversity.

    Science.gov (United States)

    Madhu, Vedichi; Das, Samar K

    2008-06-16

    The synthesis, structural characterization, and properties of a new series of asymmetrically substituted bis(dithiolene) nickel(III) compounds [Bu4N][Ni(Phdt)2] (1) (Phdt = 2-Phenyl-1,2-dithiolate), [Bu4N][Ni(NO2Phdt)2] (2) (NO2Phdt = 2-( p-nitrophenyl)-1,2-dithiolate), [Bu4N][Ni(FPhdt)2] (3) (FPhdt = 2-( p-fluorophenyl)-1,2-dithiolate), [Bu4N][Ni(ClPhdt)2] (4) (ClPhdt = 2-( p-chlorophenyl)-1,2-dithiolate), and [Bu4N][Ni(BrPhdt)2] (5) (BrPhdt = 2-( p-bromophenyl)-1,2-dithiolate) have been described. All complexes 1- 5 exhibit absorptions in the near-infrared region; the shift of these absorption bands can be tuned by the choice of the substituents on the relevant dithiolene moieties. The substituents on the dithiolene moiety are also responsible for their structural diversities. The nature of the substituents on the dithiolene moiety play an important role in tuning the redox potentials along this series. The nitro derivative (compound 2) exhibits several redox couples in its cyclic voltammogram in contrast to the other compounds in this series. The synthesis and characterization of two asymmetrically halogen substituted tetrathiafulvalene (TTF) derivatives 4,4'-bis(4-chlorophenyl)-tetrathiafulvalene ClPhTTF (6) and 4,4'-bis(4-bromophenyl)-tetrathiafulvalene (BrPhTTF) (7) have been described. One of these compounds has been structurally characterized. Iodine treatment of the monoanionic Ni(III) compound [Bu4N][Ni(ClPhdt)2] (4) results in the formation of a neutral Ni(IV) complex [Ni(ClPhdt)2] (8). All monoanionic compounds 1- 5 are Ni(III) complexes, as evidenced by electron spin resonance spectroscopy. Interestingly, strong Cl...Cl interactions are observed in the solid state structures of the chlorinated compounds 6 and 8. Finally, the structural features of compound [Ni(ClPhdt)2] (8) and the TTF derivative ClPhTTF (6) are compared based on their enormous structural similarities, and the neutral compound [Ni(ClPhdt)2] (8) is classed as the "an inorganic

  11. Britain exhibition at CERN

    CERN Multimedia

    Bertin; CERN PhotoLab

    1969-01-01

    The United Kingdom inaugurated the Industrial Exhibitions in 1968, and it wasn't till 1971 that other countries staged exhibitions at CERN. This photo was taken in 1969, at the second British exhibition, where 16 companies were present.

  12. HP-CsB5O8 : synthesis and characterization of an outstanding borate exhibiting the simultaneous linkage of all structural units of borates.

    Science.gov (United States)

    Sohr, Gerhard; Többens, Daniel M; Schmedt Auf der Günne, Jörn; Huppertz, Hubert

    2014-12-15

    The new cesium pentaborate HP-CsB5 O8 is synthesized under high-pressure/high-temperature conditions of 6 GPa and 900 °C in a Walker-type multianvil apparatus. The compound crystallizes in the orthorhombic space group Pnma (Z=4) with the parameters a=789.7(1), b=961.2(1), c=836.3(1) pm, V=0.6348(1) nm(3) , R1 =0.0359 and wR2 =0.0440 (all data). The new structure type of HP-CsB5 O8 exhibits the simultaneous linkage of trigonal BO3 groups, corner-sharing BO4 tetrahedra, and edge-sharing BO4 tetrahedra including the presence of threefold-coordinated oxygen atoms. With respect to the rich structural chemistry of borates, HP-CsB5 O8 is the second structure type possessing this outstanding combination of the main structural units of borates in one compound. The structure consists of corrugated chains of corner- and edge-sharing BO4 tetrahedra interconnected through BO3 groups forming octagonal channels. Inside these channels, cesium is 13+3-fold coordinated by oxygen atoms. (11) B MQMAS NMR spectra are analyzed to estimate the isotropic chemical shift values and quadrupolar parameters. IR and Raman spectra are obtained and compared to the calculated vibrational frequencies at the Γ-point. The high-temperature behavior is examined by means of temperature-programmed powder diffraction.

  13. Only-child and non-only-child exhibit differences in creativity and agreeableness: evidence from behavioral and anatomical structural studies.

    Science.gov (United States)

    Yang, Junyi; Hou, Xin; Wei, Dongtao; Wang, Kangcheng; Li, Yadan; Qiu, Jiang

    2016-03-08

    Different family composition and size inevitably make only-children different from non-only-children. Previous studies have focused on the differences in behaviors, such as cognitive function and personality traits, between the only-child and the non-only-child. However, there are few studies that have focused on the topic of whether different family environments influence children's brain structural development and whether behavior differentially has its neural basis between only-child and non-only-child status. Thus, in the present study, we investigated the differences in cognition (e.g., intelligence and creativity) and personality and the anatomical structural differences of gray matter volume (GMV) using voxel-based morphometry (VBM) between only-children and non-only-children. The behavioral results revealed that only-children exhibited higher flexibility scores (a dimension of creativity) and lower agreeableness scores (a dimension of personality traits) than non-only-children. Most importantly, the GMV results revealed that there were significant differences in the GMV between only-children and non-only-children that occurred mainly in the brain regions of the supramarginal gyrus, which was positively correlated with flexibility scores; the medial prefrontal cortex (mPFC), which was positively correlated with agreeableness scores; and the parahippocampal gyrus. These findings may suggest that family environment (i.e., only-child vs. non-only-child), may play important roles in the development of the behavior and brain structure of individuals.

  14. Low temperature biosynthesis of Li2O-MgO-P2O5-TiO2 nanocrystalline glass with mesoporous structure exhibiting fast lithium ion conduction.

    Science.gov (United States)

    Du, Xiaoyong; He, Wen; Zhang, Xudong; Ma, Jinyun; Wang, Chonghai; Li, Chuanshan; Yue, Yuanzheng

    2013-04-01

    We demonstrate a biomimetic synthesis methodology that allows us to create Li2O-MgO-P2O5-TiO2 nanocrystalline glass with mesoporous structure at lower temperature. We design a 'nanocrystal-glass' configuration to build a nanoarchitecture by means of yeast cell templates self-assembly followed by the controlled in-situ biomineralization of materials on the cell wall. Electrochemically active nanocrystals are used as the lamellar building blocks of mesopores, and the semiconductive glass phase can act both as the 'glue' between nanocrystals and functionalized component. The Li2O-MgO-P2O5-TiO2 nanocrystalline glass exhibits outstanding thermal stability, high conductivity and wide potential window. This approach could be applied to many other multicomponent glass-ceramics to fabricate mesoporous conducting materials for solid-state lithium batteries.

  15. Digital collections and exhibits

    CERN Document Server

    Denzer, Juan

    2015-01-01

    Today's libraries are taking advantage of cutting-edge technologies such as flat panel displays using touch, sound, and hands-free motions to design amazing exhibits using everything from simple computer hardware to advanced technologies such as the Microsoft Kinect. Libraries of all types are striving to add new interactive experiences for their patrons through exciting digital exhibits, both online and off. Digital Collections and Exhibits takes away the mystery of designing stunning digital exhibits to spotlight library trea

  16. Etruscan Culture Exhibition

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    EARLY this year an exhibition on the ancient civilization of Etruria was held at the Beijing-based China Millennium Monument.The theme of the exhibition was Etruscan Culture and on show were the most representative cultural and historical relics of this ancient civilization unearthed in the past 20 years. The 349 exhibits from various

  17. Ethics on Exhibit

    Science.gov (United States)

    Vick, Randy M.

    2011-01-01

    This article discusses ethical questions raised by an exhibition of work by an artist with a history of mental illness and the exhibition's relevance to art therapy and “outsider art” discourse on the subject. Considerations for how such an exhibit could be handled had the circumstances included an art therapist and art therapy client are…

  18. Analysis of chikungunya virus proteins reveals that non-structural proteins nsP2 and nsP3 exhibit RNA interference (RNAi) suppressor activity.

    Science.gov (United States)

    Mathur, Kalika; Anand, Abhishek; Dubey, Sunil Kumar; Sanan-Mishra, Neeti; Bhatnagar, Raj K; Sunil, Sujatha

    2016-11-30

    RNAi pathway is an antiviral defence mechanism employed by insects that result in degradation of viral RNA thereby curbing infection. Several viruses including flaviviruses encode viral suppressors of RNAi (VSRs) to counteract the antiviral RNAi pathway. Till date, no VSR has been reported in alphaviruses. The present study was undertaken to evaluate chikungunya virus (CHIKV) proteins for RNAi suppressor activity. We systematically analyzed all nine CHIKV proteins for RNAi suppressor activity using Sf21 RNAi sensor cell line based assay. Two non-structural proteins, namely, nsP2 and nsP3 were found to exhibit RNAi suppressor activity. We further validated the findings in natural hosts, namely in Aedes and in mammalian cell lines and further through EMSA and Agrobacterium infiltration in GFP silenced transgenic tobacco plants. Domains responsible for maximum RNAi suppressor activity were also identified within these proteins. RNA binding motifs in these domains were identified and their participation in RNAi suppression evaluated using site directed mutagenesis. Sequence alignment of these motifs across all species of known alphaviruses revealed conservation of these motifs emphasizing on a similar role of action in other species of alphaviruses as well. Further validation of RNAi suppressor activity of these proteins awaits establishment of specific virus infection models.

  19. Exhibiting Mozart: Rethinking Biography

    OpenAIRE

    Spring, Ulrike

    2010-01-01

    Abstract: The article analyses the new permanent exhibition in the composer Wolfgang A. Mozart’s apartment in Vienna, opened in 2006, from the curator’s perspective. The exhibition presents an approach to biographical display in which the exhibited person becomes part of a multifaceted web of contexts, and the article argues for the active deployment of the polysemic character of objects as a means of grasping the complexity of a person’s biography. Presenting a concept for the...

  20. Test Control Center exhibit

    Science.gov (United States)

    2000-01-01

    Have you ever wondered how the engineers at John C. Stennis Space Center in Hancock County, Miss., test fire a Space Shuttle Main Engine? The Test Control Center exhibit at StenniSphere can answer your questions by simulating the test firing of a Space Shuttle Main Engine. A recreation of one of NASA's test control centers, the exhibit explains and portrays the 'shake, rattle and roar' that happens during a real test firing.

  1. EXHIBITION: Accelerated Particles

    CERN Multimedia

    2004-01-01

    An exhibition of plastic arts and two evenings of performances by sound and visual artists as part of CERN's 50th anniversary celebrations. Fifty candles for CERN, an international laboratory renowned for fundamental research, is a cause for celebration. Since March this year, Geneva and neighbouring parts of France have been the venues for a wealth of small and large-scale events, which will continue until November. Given CERN's location in the commune of Meyrin, the ForuMeyrin is hosting exhibitions of plastic arts and performances entitled: Accelerated Particles. Several works will be exhibited and performed in two 'salons'. Salon des matières: An exhibition of plastic arts From Tues 12 October to Wed 3 November 2004 Tuesdays to Fridays: 16:00 to 19:00 Saturdays: 14:00 to 18:00 Exhibition open late on performance nights, entrance free Salon des particules: Musical and visual performances Tues 12 and Mon 25 October from 20:00 to 23:00 Preview evening for both events: Tues 12 October from 18:...

  2. Council Chamber exhibition

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    To complete the revamp of CERN’s Council Chamber, a new exhibition is being installed just in time for the June Council meetings.   Panels will showcase highlights of CERN’s history, using some of the content prepared for the exhibitions marking 50 years of the PS, which were displayed in the main building last November. The previous photo exhibition in the Council Chamber stopped at the 1970s. To avoid the new panels becoming quickly out of date, photos are grouped together around specific infrastructures, rather than following a classic time-line. “We have put the focus on the accelerators – the world-class facilities that CERN has been offering researchers over the years, from the well-known large colliders to the lesser-known smaller facilities,” says Emma Sanders, who worked on the content. The new exhibition will be featured in a future issue of the Bulletin with photos and an interview with Fabienne Marcastel, designer of the exhibit...

  3. Exhibition in Sight

    Science.gov (United States)

    Wasserman, Burton

    1978-01-01

    Ludwig Mies van der Rohe is known primarily as an architect. However, he also designed chairs and tables. Discusses an exhibit held in New York City a few months ago which showed how well the famous architect achieved his goals in the area of furniture design. (Author/RK)

  4. Exhibitions in Sight

    Science.gov (United States)

    Wasserman, Burton

    1977-01-01

    Today, few artists make serving vessels on a monumental scale. Here artists compete in this unique area of specialization prompted by the Campbell Museum in Camden, New Jersey, which is dedicated to collecting and exhibiting the very best in soup tureens. (Author/RK)

  5. EXHIBITION: Accelerated Particles

    CERN Multimedia

    2004-01-01

    http://www.cern.ch/cern50/ An exhibition of plastic arts and two evenings of performances by sound and visual artists as part of CERN's fiftieth anniversary celebrations. The fiftieth anniversary of a world famous organization like CERN, an international laboratory specializing in fundamental research, is a cause for celebration. Since March this year, Geneva and neighbouring parts of France have been the venues for a wealth of small and large-scale events, which will continue until November. Given CERN's location in the commune of Meyrin, the ForuMeyrin is hosting two "salons" consisting of an exhibition of plastic arts and evenings of music and visual arts performances with the collective title of "Accelerated Particles". Several works will be exhibited and performed. Salon des matières: An exhibition of plastic arts Until Wednesday 3 November 2004. Tuesdays to Fridays: 4.00 p.m. to 7.00 p.m. Saturdays: 2.00 p.m. to 6.00 p.m. Doors open late on the evening of the performances. Salon des ...

  6. CERN permanent exhibitions

    CERN Multimedia

    2016-01-01

    Explore by yourself the issues CERN's physicists are trying to solve: given that the entire universe is made of particles, where do they come from? Why do they behave in the way they do? Discover the massive apparatus used by physicists at CERN, like the LHC, and see how each part works. And if you have more time on site, follow the LHC circuit at ground level to understand in situ this giant machine. Enter our exhibitions. Welcome!

  7. Droplet Lamp Design exhibition

    OpenAIRE

    Unver, Ertu; Dean, Lionel Theodore

    2011-01-01

    This paper describes experiments in the use of digital fluid simulation techniques within a\\ud product design context. It discusses the adoption and adaptation of virtual modelling tools in\\ud 3D creative practice. This work is exhibited at EuroMold, the world-wide fair in Germany for\\ud mold making, tooling, design and application development with around 60.000 visitors and lasts\\ud 4 days. The fair brings together professionals from design, prototyping and manufacturing.

  8. Upcycling CERN Exhibitions

    CERN Multimedia

    Katarina Anthony

    2015-01-01

    Summer is coming - and with it, a new Microcosm exhibition showcasing CERN (see here). But while the new exhibit is preparing to enchant visitors, many have been asking about the site's former content. Will it simply be out with the old and in with the new? Not as such!   The plasma ball from Microcosm is now on display at the LHCb site. As Microcosm's new content is moving in, its old content is moving up. From LHCb to IdeaSquare, former Microcosm displays and objects are being installed across the CERN site. "Microcosm featured many elements that were well suited to life outside of the exhibition," says Emma Sanders, Microcosm project leader in the EDU group. "We didn't want this popular content to go to waste, and so set out to find them new homes across CERN." The LHCb experiment has received a number of Microcosm favourites, including the Rutherford experiment, the cosmic ray display and the Thomson experiment. "We&...

  9. Online Exhibits & Concept Maps

    Science.gov (United States)

    Douma, M.

    2009-12-01

    Presenting the complexity of geosciences to the public via the Internet poses a number of challenges. For example, utilizing various - and sometimes redundant - Web 2.0 tools can quickly devour limited time. Do you tweet? Do you write press releases? Do you create an exhibit or concept map? The presentation will provide participants with a context for utilizing Web 2.0 tools by briefly highlighting methods of online scientific communication across several dimensions. It will address issues of: * breadth and depth (e.g. from narrow topics to well-rounded views), * presentation methods (e.g. from text to multimedia, from momentary to enduring), * sources and audiences (e.g. for experts or for the public, content developed by producers to that developed by users), * content display (e.g. from linear to non-linear, from instructive to entertaining), * barriers to entry (e.g. from an incumbent advantage to neophyte accessible, from amateur to professional), * cost and reach (e.g. from cheap to expensive), and * impact (e.g. the amount learned, from anonymity to brand awareness). Against this backdrop, the presentation will provide an overview of two methods of online information dissemination, exhibits and concept maps, using the WebExhibits online museum (www.webexhibits.org) and SpicyNodes information visualization tool (www.spicynodes.org) as examples, with tips on how geoscientists can use either to communicate their science. Richly interactive online exhibits can serve to engage a large audience, appeal to visitors with multiple learning styles, prompt exploration and discovery, and present a topic’s breadth and depth. WebExhibits, which was among the first online museums, delivers interactive information, virtual experiments, and hands-on activities to the public. While large, multidisciplinary exhibits on topics like “Color Vision and Art” or “Calendars Through the Ages” require teams of scholars, user interface experts, professional writers and editors

  10. Space Shuttle Cockpit exhibit

    Science.gov (United States)

    2000-01-01

    Want to sit in the cockpit of the Space Shuttle and watch astronauts work in outer space? At StenniSphere, you can do that and much more. StenniSphere, the visitor center at John C. Stennis Space Center in Hancock County, Miss., presents 14,000-square-feet of interactive exhibits that depict America's race for space as well as a glimpse of the future. StenniSphere is open free of charge from 9 a.m. to 5 p.m. daily.

  11. Anniversary Exhibition. Nechvolodov.

    Directory of Open Access Journals (Sweden)

    - -

    2006-03-01

    Full Text Available On the 10th of August, 2005 in Tartu (the second biggest educational and cultural city in Estonia Stanislav Nechvolodov's exhibition was opened to show the 5-year cycle of his work, traditional for the author and his admirers. At the opening ceremony Nechvolodov said that the exhibition was the last one and appointed on his 70th anniversary.The architectural and building society in Irkutsk remembers Stanislav Nechvolodov as an architect working on dwelling and civil buildings in 1960-70s. Below are some extracts from the Estonian press.«Postimees» newspaper, December 1993. The interview «Expressionistic naturalist, conservative Nechvolodov» by journalist Eric Linnumyagi. He asks about all the details and describes the troubles experienced by Nechvolodov during the perestroika period in Estonia, for example: the Tartu University refused to install the sculpture of Socrat, the art school refused to engage him as an instructor, the sculpture of Socrat moved to Vrotzlav, Poland, and Nechvolodov moved to Poland to read lectures there.«Tartu» newspaper, November 2000. Mats Oun, artist, says in the article «Nechvolodov: a man of Renaissance»: «Nechvolodov works in Estonia, his works are placed in many local and foreign museums. Regardless some insignificant faults, he deserves a high estimation, and his manysided open exhibition can be an example for other artists. He is a man of Renaissance».

  12. Structural, Magnetic, and Photomagnetic Studies of a Mononuclear Iron(II) Derivative Exhibiting an Exceptionally Abrupt Spin Transition. Light-Induced Thermal Hysteresis Phenomenon.

    Science.gov (United States)

    Létard, Jean-François; Guionneau, Philippe; Rabardel, Louis; Howard, Judith A. K.; Goeta, Andres E.; Chasseau, Daniel; Kahn, Olivier

    1998-08-24

    The new spin-crossover compound Fe(PM-BiA)(2)(NCS)(2) with PM-BiA = N-(2-pyridylmethylene)aminobiphenyl has been synthesized. The temperature dependence of chi(M)T (chi(M) = molar magnetic susceptibility and T = temperature) has revealed an exceptionally abrupt transition between low-spin (LS) (S = 0) and high-spin (HS) (S = 2) states with a well-reproducible hysteresis loop of 5 K (T(1/2) downward arrow = 168 K and T(1/2) upward arrow = 173 K). The crystal structure has been determined both at 298 K in the HS state and at 140 K in the LS state. The spin transition takes place without change of crystallographic space group (Pccn with Z = 4). The determination of the intermolecular contacts in the LS and HS forms has revealed a two-dimensional structural character. The enthalpy and entropy variations, DeltaH and DeltaS, associated with the spin transition have been deduced from heat capacity measurements. DeltaS (= 58 J K(-)(1) mol(-)(1)) is larger than for other spin transition bis(thiocyanato) iron(II) derivatives. At 10 K the well-known LIESST (light-induced excited spin state trapping) effect has been observed within the SQUID cavity, by irradiating a single crystal or a powder sample with a Kr(+) laser coupled to an optical fiber. The magnetic behavior recorded under light irradiation in the warming and cooling modes has revealed a light-induced thermal hysteresis (LITH) effect with 35 LS relaxation after LIESST has been found to deviate from first-order kinetics. The kinetics has been investigated between 10 and 78 K. A thermally activated relaxation behavior at elevated temperatures and a nearly temperature independent tunneling mechanism at low temperatures have been observed. The slow rate of tunneling from the metastable HS state toward the ground LS state may be explained by the unusually large change in Fe-N bond lengths between these two states.

  13. FT-Raman study of deferoxamine and deferiprone exhibits potent amelioration of structural changes in the liver tissues of mice due to aluminum exposure

    Science.gov (United States)

    Sivakumar, S.; Khatiwada, Chandra Prasad; Sivasubramanian, J.; Raja, B.

    2014-01-01

    The present study inform the alterations on major biochemical constituents such as lipids, proteins, nucleic acids and glycogen along with phosphodiester linkages, tryptophan bands, tyrosine doublet, disulfide bridge conformations, aliphatic hydrophobic residue, and salt bridges in liver tissues of mice using Fourier transform Raman spectroscopy. In amide I, amide II and amide III, the area value significant decrease due structural alteration in the protein, glycogen and triglycerides levels but chelating agents DFP and DFO upturned it. Morphology changes by aluminium induced alterations and recovery by chelating agents within liver tissues known by histopathological examination. Concentrations of trace elements were found by ICP-OES. FT-Raman study was revealed to be in agreement with biochemical studies and demonstrate that it can successfully specify the molecular alteration in liver tissues. The tyrosyl doublet ratio I899/I831 decreases more in aluminum intoxicated tissues but treatment with DFP and DFO + DFP brings back to nearer control value. This indicates more variation in the hydrogen bonding of the phenolic hydroxyl group due to aluminum poisoning. The decreased Raman intensity ratio (I3220/I3400) observed in the aluminum induced tissues suggests a decreased water domain size, which could be interpreted in terms of weaker hydrogen-bonded molecular species of water in the aluminum intoxicated liver tissues. Finally, FT-Raman spectroscopy might be a useful tool for obtained successfully to indicate the molecular level changes.

  14. Charge and Spin States in Schiff Base Metal Complexes with a Disiloxane Unit Exhibiting a Strong Noninnocent Ligand Character: Synthesis, Structure, Spectroelectrochemistry, and Theoretical Calculations.

    Science.gov (United States)

    Cazacu, Maria; Shova, Sergiu; Soroceanu, Alina; Machata, Peter; Bucinsky, Lukas; Breza, Martin; Rapta, Peter; Telser, Joshua; Krzystek, J; Arion, Vladimir B

    2015-06-15

    Mononuclear nickel(II), copper(II), and manganese(III) complexes with a noninnocent tetradentate Schiff base ligand containing a disiloxane unit were prepared in situ by reaction of 3,5-di-tert-butyl-2-hydroxybenzaldehyde with 1,3-bis(3-aminopropyl)tetramethyldisiloxane followed by addition of the appropriate metal(II) salt. The ligand H2L resulting from these reactions is a 2:1 condensation product of 3,5-di-tert-butyl-2-hydroxybenzaldehyde with 1,3-bis(3-aminopropyl)tetramethyldisiloxane. The resulting metal complexes, NiL·0.5CH2Cl2, CuL·1.5H2O, and MnL(OAc)·0.15H2O, were characterized by elemental analysis, spectroscopic methods (IR, UV-vis, X-band EPR, HFEPR, (1)H NMR), ESI mass spectrometry, and single crystal X-ray diffraction. Taking into account the well-known strong stabilizing effects of tert-butyl groups in positions 3 and 5 of the aromatic ring on phenoxyl radicals, we studied the one-electron and two-electron oxidation of the compounds using both experimental (chiefly spectroelectrochemistry) and computational (DFT) techniques. The calculated spin-density distribution and localized orbitals analysis revealed the oxidation locus and the effect of the electrochemical electron transfer on the molecular structure of the complexes, while time-dependent DFT calculations helped to explain the absorption spectra of the electrochemically generated species. Hyperfine coupling constants, g-tensors, and zero-field splitting parameters have been calculated at the DFT level of theory. Finally, the CASSCF approach has been employed to theoretically explore the zero-field splitting of the S = 2 MnL(OAc) complex for comparison purposes with the DFT and experimental HFEPR results. It is found that the D parameter sign strongly depends on the metal coordination geometry.

  15. The structure of a purple acid phosphatase involved in plant growth and pathogen defence exhibits a novel immunoglobulin-like fold

    Directory of Open Access Journals (Sweden)

    Svetlana Vladimirovna Antonyuk

    2014-03-01

    Full Text Available Phosphatases function in the production, transport and recycling of inorganic phosphorus, which is crucial for cellular metabolism and bioenergetics, as well as in bacterial killing, since they are able to generate reactive oxygen species via Fenton chemistry. Diphosphonucleotide phosphatase/phosphodiesterase (PPD1, a glycoprotein plant purple acid phosphatase (PAP from yellow lupin seeds, contains a bimetallic Fe–Mn catalytic site which is most active at acidic pH. Unlike other plant PAPs, PPD1 cleaves the pyrophosphate bond in diphosphonucleotides and the phosphodiester bond in various phosphodiesters. The homohexameric organization of PPD1, as revealed by a 1.65 Å resolution crystal structure and confirmed by solution X-ray scattering, is unique among plant PAPs, for which only homodimers have previously been reported. A phosphate anion is bound in a bidentate fashion at the active site, bridging the Fe and Mn atoms in a binding mode similar to that previously reported for sweet potato PAP, which suggests that common features occur in their catalytic mechanisms. The N-terminal domain of PPD1 has an unexpected and unique fibronectin type III-like fold that is absent in other plant PAPs. Here, the in vitro DNA-cleavage activity of PPD1 is demonstrated and it is proposed that the fibronectin III-like domain, which `overhangs' the active site, is involved in DNA selectivity, binding and activation. The degradation of DNA by PPD1 implies a role for PPD1 in plant growth and repair and in pathogen defence.

  16. 2007Fairs & Exhibitions in China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ The 6th China (Guangzhou) International Seasoning Exhibition Date: May 11-13 Founded in: 2003.05 Venues: Guangzhou Int'l Convention &Exhibition Center (Pazhou) Exhibits: Seasonings, food additives, relevant material,equipment, service and publications

  17. 2005 Fairs & Exhibitions in China

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Harbin China International Winter Goods Exhibition DATE: Jan. 5-9 FREQUENCY: Annual FOUNDED TIME: Dec. 2001 VENUE: Harbin China International Conference & Exhibition Center EXHIBITS: winter sports goods and outdoor devices

  18. The Report of Virtual Exhibition Software Development

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The main structure and key techniques of our Vir tual ExhibitionSoftware are summarized. It demonstrates the practice of Softwa re Engineering during the development of our project and discusses the use of UML in it.

  19. The Optimization Model of the Supply Chain Structure of Exhibition%会展供应链结构优化模型构建与系统优化

    Institute of Scientific and Technical Information of China (English)

    申强; 杨为民; 刘笑冰

    2014-01-01

    Considering the rapid development of the convention and exhibition industry in China and characteristics of supply chain management,this paper defines supply chain of the convention and exhibition industry based on principles of manufacturing supply chain and service supply chain management,combining with characteristics of the convention and exhibition industry.Morever,it constructs the optimization model of the supply chain structure and proposes the optimization concrete content and measures for the optimization model.The result shows that the supply chain of exhibition integrates the content and the characteristics of the manufacturing and service supply chain,and the key to improve its performance is optimizing the structure of its organization,implementation of information sharing and restriction of the behaviors of the participates.%考虑到中国会展产业的迅速发展和供应链管理特点,本文基于制造供应链和服务供应链管理理论,结合会展产业自身特征,在对会展供应链进行定义的基础上,构建会展供应链结构优化模型,并针对该优化模型提出具体的优化内容和措施。研究表明,会展供应链融合了制造供应链和服务供应链的特性和内容,其绩效提高的关键在于优化自身组织结构、实现参与主体的信息共享并约束参与主体的行为。

  20. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    Gaïa Manuella Cany Du 10 au 28 avril 2017 CERN Meyrin, Bâtiment principal Oiseau - Manuella Cany. Tableaux abstraits inspirés de vues satellites ou photos prises du ciel. Certains sont à la frontière du figuratif alors que d'autres permettent de laisser libre cours à son imagination. Aux détails infinis, ces tableaux sont faits pour être vus de loin et de près grâce à une attention toute particulière apportée aux effets de matières et aux couleurs le long de volutes tantôt nuancées tantôt contrastées.   Pour plus d’informations : staff.association@cern.ch | Tél: 022 766 37 38

  1. Exhibition

    CERN Multimedia

    Staff Association

    2011-01-01

    Jan Hladky, physicien de l'Institut de Physique de l'Académie des Sciences de la République tchèque, et membre de la collaboration Alice, expose ses œuvres au Bâtiment principal du 20 avril au 6 mai. Son exposition est dédiée aux victimes du séisme de Sendai. Des copies de ses œuvres seront mises en vente et les sommes récoltées seront versées au profit des victimes.

  2. Exhibition

    CERN Multimedia

    Staff Association

    2016-01-01

    The Elementary Particles of Painting Alfonso Fratteggiani Bianchi and Ermanno Imbergamo From September 26 to October 7, 2016 CERN Meyrin, Main Building With intentions similar to those of CERN physicists, the artist Alfonso Fratteggiani Bianchi investigates the color pigment, studying its interaction with light and with the support on which it is deposited. He creates monochrome paintings by spreading the color pigment in the pure state on stones, without using glue or any other type of adhesive. With intentions similar to artists, the physicist Ermanno Imbergamo investigates the use of luminescent wavelength shifters, materials commonly used in Particle Physics, for art. He creates other monochrome artworks, which disclose further aspects of interaction among light, color pigments and support. For more information: staff.association@cern.ch | Tel: 022 767 28 19

  3. Exhibition

    CERN Multimedia

    Staff Association

    2016-01-01

    La mosaïque ou quand détruire permet de construire Lauren Decamps Du 28 novembre au 9 décembre 2016 CERN Meyrin, Bâtiment principal Paysage d'Amsterdam - Lauren Decamps On ne doit jamais rien détruire qu'on ne soit sûr de pouvoir remplacer aussi avantageusement " écrivait Plutarque dans ses Œuvres morales du 1er siècle après JC. L'artiste mosaïste Lauren Decamps adhère à cette idée et tente à sa manière de donner une nouvelle vie à ses matériaux en les taillant puis les réassemblant, créant ainsi des œuvres abstraites et figuratives.

  4. Exhibition

    CERN Multimedia

    Staff Association

    2016-01-01

    COLORATION Sandra Duchêne From September 5 to 16, 2016 CERN Meyrin, Main Building La recherche de l’Universel. Après tout ! C’est de l’Amour ! What else to say ? …La couleur, l’ENERGIE de la vie…

  5. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    Œuvres recentes Fabienne Wyler Du 6 au 17 février 2017 CERN Meyrin, Bâtiment principal L'escalier du diable B - aquarelle, encre de Chine XLV - Fabienne Wyler. En relation avec certains procédés d’écriture contemporaine (par ex. Webern ou certaines musiques conçues par ordinateur), les compositions picturales de Fabienne Wyler s’élaborent à partir de « modules » (groupes de quadrangles) qu’elle reproduit en leur faisant subir toutes sortes de transformations et de déplacements : étirements, renversements, rotations, effet miroir, transpositions, déphasages, superpositions, etc., et ceci à toutes les échelles. Au fil des œuvres sont apparues des séries intitulées, Bifurcations, Intermittences, Attracteurs étranges, Polyrythmies. Ces titres ont un lien &e...

  6. Exhibition

    CERN Multimedia

    Staff Association

    2014-01-01

    Energie sombre, matière noire J.-J. Dalmais - J. Maréchal Du 11 au 27 novembre 2014, CERN Meyrin, Bâtiment principal A l’image des particules atomiques qui ont tissé des liens pour créer la matière, deux artistes haut bugistes croisent leurs regards et conjuguent leurs expressions singulières pour faire naître une vision commune de l’univers, produit des forces primordiales. Les sculptures de Jean-Jacques Dalmais et les peintures de Jacki Maréchal se rencontrent pour la première fois et se racontent par un enrichissement mutuel la belle histoire de la Vie. Dialogue magique des œuvres en mouvement qui questionnent en écho l’énergie sombre et la matière noire. Cette harmonieuse confluence de jeux de miroir et de résonnance illumine de poésie et de sobriété l’espace expos&...

  7. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    Harmonie Nathalie Lenoir Du 4 au 15 septembre 2017 CERN Meyrin, Bâtiment principal Peindre est un langage. Le tracé du pinceau sur le lin en est l'expression. A qui appartient un tableau en définitive ? A celui qui l'a peint ? A celui qui le regarde ? A celui qui l'emporte ? La peinture est une émotion partagée... Laissez-vous projeter de l'autre côté de la toile, prenez un moment pour rêver, en harmonie avec les éléments, parce-que la peinture parle à votre âme… Pour plus d’informations et demandes d’accès : staff.association@cern.ch | Tél : 022 766 37 38

  8. Exhibition

    CERN Document Server

    Staff Association

    2017-01-01

    Firmament des toiles Joëlle Lalagüe Du 6 au 16 juin 2017 CERN Meyrin, Bâtiment principal Phylaë Voyage - Joëlle Lalagüe. Each picture is an invitation for a cosmic trip. This is a whispering of soul, which comes from origins. A symphony of the world, some notes of love, a harmony for us to fly to infinity. Pour plus d’informations et demandes d'accès : staff.association@cern.ch | Tél: 022 766 37 38

  9. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    La couleur des jours oriSio Du 2 au 12 mai 2017 CERN Meyrin, Bâtiment principal oriSio - Motus Suite à un fort intérêt pour la Chine et une curiosité pour un médium très ancien, la laque ! Je réinterprète cet art à travers un style abstrait. Je présente ici des laques sur aluminium, travaillés au plasma et ensuite colorés à l’aide de pigments pour l’essentiel. Mes œuvres je les veux brutes, déchirées, évanescentes, gondolées, voire trouées mais avec une belle approche de profondeur de la couleur.   Pour plus d’informations : staff.association@cern.ch | Tél: 022 766 37 38

  10. Exhibition

    CERN Multimedia

    Staff Association

    2016-01-01

    La mosaïque ou quand détruire permet de construire Lauren Decamps Du 28 novembre au 9 décembre 2016 CERN Meyrin, Bâtiment principal Paysage d'Amsterdam - Lauren Decamps On ne doit jamais rien détruire qu'on ne soit sûr de pouvoir remplacer aussi avantageusement " écrivait Plutarque dans ses Œuvres morales du 1er siècle après JC. L'artiste mosaïste Lauren Decamps adhère à cette idée et tente à sa manière de donner une nouvelle vie à ses matériaux en les taillant puis les réassemblant, créant ainsi des œuvres abstraites et figuratives.

  11. Exhibition

    CERN Multimedia

    Staff Association

    2017-01-01

    Still Life Jérémy Bajulaz Du 25 septembre au 6 octobre 2017 CERN Meyrin, Main Building (Aubergine - Jérémy Bajulaz) Né en 1991 en Haute-Savoie, France. Diplômé de l'Ecole Emile Cohl à Lyon, Jérémy Bajulaz intègre en 2014 le programme d'artiste en résidence au Centre Genevois de Gravure Contemporaine. C'est là que son travail prendra corps, autour de la lumière et de ses vibrations aux travers de sujets comme le portrait et la nature morte, dans le souci de l'observation; le regard prenant une place importante dans le processus créatif. Lauréat 2017 du VII Premio AAAC, son travail a été présenté dans de nombreuses expositions collectives, en 2015 au Bâtiment d’Art Contemporain de Genève, en 2016 au 89e Salon de Lyon et du S...

  12. Application and Construction Of The Beam String Structure For Xiamen International Conference & Exhibition CenterⅡ%厦门国际会展中心二期张弦梁结构应用与实践

    Institute of Scientific and Technical Information of China (English)

    庄学臻

    2014-01-01

    厦门会展中心二期展厅跨度81米,施工工期异常紧张,采用张弦梁体系取得技术安全、质量可靠、工期短、造价经济、结构美观的良好效果,通过对会展中心张弦梁体系的选型、设计、施工难点分析,介绍了张弦梁结构的受力性能及应用实践,可供类似工程参考借鉴。%The roof structure system of the Conference and Exhibition Center is a beam string structure , its pre-stressing is very difficult . A minute description of the pre -stressing construction plan is given .Some first-phase preparations such as the construction simulation calculation and pre-stressing device design are introduced .The construction monitor plan and the synchronism control measure are briefly accounted .According to the construction simulation results and site construction monitoring result , the feature of pre -stress and steel structure construction of the structure are proposed .

  13. Ce{sub 2}B{sub 8}O{sub 15}. High-pressure synthesis and crystal structure determination of a rare-earth polyborate exhibiting a new 'Fundamental Building Block'

    Energy Technology Data Exchange (ETDEWEB)

    Glaetzle, Matthias; Heymann, Gunter; Huppertz, Hubert [Innsbruck Univ. (Austria). Inst. fuer Allgemeine, Anorganische und Theoretische Chemie

    2013-10-01

    The new cerium polyborate Ce{sub 2}B{sub 8}O{sub 15} was synthesized under high-pressure/high-temperature conditions of 6 GPa and 1050 C in a Walker-type multianvil apparatus. The single-crystal structure determination revealed that the new compound crystallizes in the space group P2/c with the lattice parameters a = 916.6(2), b = 421.0(1), c = 1248.9(3) pm, {beta} = 116.7(1) , V = 0.4303(2) nm{sup 3}, R1 = 0.0356, and wR2 = 0.0504. The crystal structure of Ce{sub 2}B{sub 8}O{sub 15} exhibits a new fundamental building block (FBB) in borate chemistry that consists of four BO{sub 4} tetrahedra and can be written as 4{open_square}: [{Phi}] left angle 3{open_square} right angle vertical stroke {open_square} vertical stroke. These FBB are interconnected via common corners, forming a complex threedimensional network that contains the Ce{sup 3+} cations. Ce{sub 2}B{sub 8}O{sub 15} represents the most boron rich rare-earth borate synthesized under high-pressure/high-temperature conditions so far. We report about the synthetic conditions, structural details, thermal behaviour, and the IR/Raman spectra of Ce{sub 2}B{sub 8}O{sub 15}. (orig.)

  14. Small non-polar complexes exhibiting significant piezoelectric properties: Solvothermal synthesis and crystal structures of MO5V(tren)·H2O (M=Mo and W; tren=tris(2-aminoethyl)amine)

    Science.gov (United States)

    Rasmussen, M.; Näther, C.; Bismayer, U.; Bensch, W.

    2012-11-01

    The two isostructural complexes MO5V(tren)·H2O (M=Mo (1) and W (2)) were synthesized under solvothermal conditions at pH≈12 crystallizing in the non-centrosymmetric space group P212121. The structures are constructed by a distorted tetrahedral [MO4]2- anion bound via one shared oxygen atom to a severely distorted [VIVN4O]2+ complex completing the octahedral coordination around the V centre. The two O atoms in the VN4O2 octahedron are in cis position. The two compounds represent rare examples where the [MO4]2- anion is acting as a ligand. Both compounds exhibit a piezoelectric effect which is more pronounced for M=Mo. The samples are further characterized with IR and UV/Vis spectroscopy and thermal analysis.

  15. The World of Virtual Exhibitions

    Directory of Open Access Journals (Sweden)

    Irena Eiselt

    2013-09-01

    Full Text Available EXTENDED ABSTRACTSpecial collections of the National and University Library (NUK hide a lot of items of precious value. The Slovenian cultural heritage is stored on paper or on other media as a part of the library’s Manuscripts, Incunabula and Rare Books Collection, Old Prints Collection, Maps and Pictorial Collection, Music Collection, Ephemera Collection, Serials Collection, and Slovenian Diaspora Publications Collection. Only a small part of the treasures is temporary revealed to the public on special exhibitions. The idea of virtual exhibitions of library treasures was born in 2005. The library aimed to exhibit precious items of special collections of high historical or artistic value. In 2008 the first two virtual exhibitions were created in-house offering access to the rich collections of old postcards of Ljubljana at the beginning of 20th century kept in the Maps and Pictorial Collection of NUK. They were soon followed by other virtual exhibitions. At the beginning they were organised in the same way as physical exhibitions, afterwards different programs were used for creation of special effects (for ex. 3D wall. About two years ago it was decided that the creation of virtual exhibitions will be simplified. Files of digitised and borndigital library materials in jpg format are imported to MS PowerPoint 2010. Each jpg file is now formatted by adding a frame, a description … to the slides which are saved as jpg files. The last step is the import of jpg files into Cooliris application used for NUK web exhibitions. In the paper the virtual exhibition design and creation, the technical point of view and criteria for the selection of exhibition content are explained following the example of the virtual exhibitions the Old Postcards of Ljubljana, Photo Ateliers in Slovenia, a collection of photographs Four Seasons by Fran Krašovec and photos of Post-Earthquake Ljubljana in 1895.

  16. Auto Technology Exhibition in Tianjing

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ The 4th International Automotive Technology Exhibition Tianjing2009,jointly hosted by the Society of Automotive Engineers of China(SAE-China),China Automotive Technology and Research Center(CATRC)and Tianjin Economic-Technological Development Area(TETD),is to be held in Tianjin Binhai International Convention and Exhibition Center from August 27 to August 30 this year.In line with China's national 11th Five-year Plan,The Automobile Industry Revitalization and Adjustments Planning and The Equipment Manufacturing Revitalization and Adjustments Planning,this Exhibition,centered on the theme of automobile and equipment manufacturing,arranges the exhibition halls respectively for private autos,commercial autos and equipment manufacturing etc.

  17. Photowalk Exhibition opens at Microcosm

    CERN Document Server

    Katarina Anthony

    2011-01-01

    The winning photographs from the 2010 Global Particle Physics Photowalk competition will go on display at Microcosm from 11 February to 2 April. The exhibition is part of a global photography event taking place over three continents, with Photowalk exhibitions opening simultaneously at Fermilab in the US, KEK in Japan and here at CERN.   DESY wire chamber - First place people's choice; second place global jury competition. Photographer: Hans-Peter Hildebrandt  If you were one of the 1,300 photography lovers who voted in last year’s Photowalk competition, this exhibition is your chance to see the winning entries in print. The exhibition will take place in the downstairs gallery of Microcosm, overlooking the garden. 15 photographs will be on display, with each of the laboratories that participated in Photowalk represented by their 3 winning entries. Among them will be the “people’s choice” sunburst photo of a particle detector at DESY (Photo 1), and...

  18. Small non-polar complexes exhibiting significant piezoelectric properties: Solvothermal synthesis and crystal structures of MO{sub 5}V(tren){center_dot}H{sub 2}O (M=Mo and W; tren=tris(2-aminoethyl)amine)

    Energy Technology Data Exchange (ETDEWEB)

    Rasmussen, M.; Naether, C. [Institut fuer Anorganische Chemie, Christian-Albrechts-Universitaet Kiel, Max-Eyth-Str. 2, D-24118 Kiel (Germany); Bismayer, U. [Mineralogisch-Petrographisches Institut, Universitaet Hamburg, Grindelallee 48 20146 Hamburg (Germany); Bensch, W., E-mail: wbensch@ac.uni-kiel.de [Institut fuer Anorganische Chemie, Christian-Albrechts-Universitaet Kiel, Max-Eyth-Str. 2, D-24118 Kiel (Germany)

    2012-11-15

    The two isostructural complexes MO{sub 5}V(tren){center_dot}H{sub 2}O (M=Mo (1) and W (2)) were synthesized under solvothermal conditions at pH Almost-Equal-To 12 crystallizing in the non-centrosymmetric space group P2{sub 1}2{sub 1}2{sub 1}. The structures are constructed by a distorted tetrahedral [MO{sub 4}]{sup 2-} anion bound via one shared oxygen atom to a severely distorted [V{sup IV}N{sub 4}O]{sup 2+} complex completing the octahedral coordination around the V centre. The two O atoms in the VN{sub 4}O{sub 2} octahedron are in cis position. The two compounds represent rare examples where the [MO{sub 4}]{sup 2-} anion is acting as a ligand. Both compounds exhibit a piezoelectric effect which is more pronounced for M=Mo. The samples are further characterized with IR and UV/Vis spectroscopy and thermal analysis. - Graphical abstract: The complexes [(V(tren)O)(MO4)]{center_dot}H2O (M = Mo, W; tren = tris(2-aminoethyl)amine)) composed of vertex-linked [MO4]{sup 2-} tetrahedron and [VN4O6]{sup 2+}octahedron. Highlights: Black-Right-Pointing-Pointer [MO{sub 4}]{sup 2-} tetrahedron (M=Mo, W) acting as ligand. Black-Right-Pointing-Pointer Jahn-Teller and steric distortion of the [VN{sub 4}O{sub 2}]{sup 2+} octahedron. Black-Right-Pointing-Pointer Non-centrosymmetric complexes exhibiting pronounced piezoelectric effect.

  19. Globe exhibit wins international acclaim

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    The Globe’s “Universe of Particles” exhibition has recently received four prestigious awards for its avant-garde design. This external praise is great encouragement for the CERN exhibitions currently on the drawing board.   The Universe of Particles exhibition has won 4 awards for its avant-garde design. Back in 2008, the design company Atelier Brückner was presented with a challenge: to design the layout of a new permanent exhibition for CERN, one that would epitomize both the Organization and its research. The brief was concise but complex: the exhibit had to be symbolic of the Organization, use modern technology, engage and immerse visitors, and, preferably, use touch-screen technology. With the help of IArt, an interactive technology firm, and based on the content provided by CERN’s Education Group, Atelier Brückner developed the “Universe of Particles” exhibit as it is today. Its principal concept centred on the s...

  20. Greenhouse Earth: A Traveling Exhibition

    Energy Technology Data Exchange (ETDEWEB)

    Booth, W.H.; Caesar, S.

    1992-09-01

    The Franklin Institute Science Museum provided an exhibit entitled the Greenhouse Earth: A Traveling Exhibition. This 3500 square-foot exhibit on global climate change was developed in collaboration with the Association of Science-Technology Centers. The exhibit opened at The Franklin Institute on February 14, 1992, welcoming 291,000 visitors over its three-month stay. During its three-year tour, Greenhouse Earth will travel to ten US cities, reaching two million visitors. Greenhouse Earth aims to deepen public understanding of the scientific issues of global warming and the conservation measures that can be taken to slow its effects. The exhibit features hands-on exhibitry, interactive computer programs and videos, a theater production, a demonstration cart,'' guided tours, and lectures. supplemental educational programs at the Institute included a teachers preview, a symposium on climate change, and a satellite field trip.'' The development of Greenhouse Earth included front-end and formative evaluation procedures. Evaluation includes interviews with visitors, prototypes, and summative surveys for participating museums. During its stay in Philadelphia, Greenhouse Earth was covered by the local and national press, with reviews in print and broadcast media. Greenhouse Earth is the first large-scale museum exhibit to address global climate change.

  1. A simple coordination complex exhibiting colour change on slight structural modification: Synthesis and crystal structures of violet and yellow forms of [NiII(opda)2(NCS)2] (opda = orthophenylenediamine)

    Indian Academy of Sciences (India)

    Sabbani Supriya; Samar K Das

    2010-09-01

    The violet-coloured compound [NiII(opda)2(NCS)2] (1) undergoes colour change to strawyellow colour retaining its molecular composition on standing over long period of time at room temperature in the solid state. Compound 1 (violet form) and its yellow-form [NiII(opda)2(NCS)2] (2) (opda = orthophenylenediammine) have been characterized by routine spectroscopic methods and single crystal X-ray diffraction analysis. Compound 1 crystallizes in monoclinic space group 21/ and its yellow form (compound 2) retains same space group. Their crystal structures show an intricate supramolecular network based on N-H$\\cdots$S hydrogen bonds, that involve amine and thiocyanate groups coordinated to nickel(II).

  2. Exhibition - Mathematics, A Beautiful Elsewhere

    CERN Multimedia

    2011-01-01

    From 21 October 2011 to 18 March 2012, the Fondation Cartier pour l’art contemporain will present the exhibition Mathematics: A Beautiful Elsewhere, an exhibition developed in association with the Institut des Hautes Études Scientifiques (IHÉS) and under the patronage of UNESCO. For this unprecedented event, the foundation invited mathematicians to work with artists with whom it has previously worked to create an exhibition that allows visitors to see, hear, do, interpret and think about mathematics. By bringing mathematics into its premises, the Fondation Cartier is itself undergoing the “sudden change of scenery” described by mathematician Alexandre Grothendieck. More information is available here. Fondation Cartier pour l’art contemporain 261, boulevard Raspail 75014 Paris http://fondation.cartier.com Private Visit For professors, researchers and all the staff of Mathematics departments...

  3. Green Revolution for Exhibition Industry

    Institute of Scientific and Technical Information of China (English)

    Yan Manman

    2010-01-01

    @@ Shanghai World Expo is widely regarded as another grand international pageant, so many people thought that the opening ceremony must be as much magnificent and brilliant as the opening ceremony for Beijing Olympics.However, it was revealed by Wan Jifei, Executive Director of the ExecutiveCommittee of the Shanghai World Expo that the opening ceremony of the Expo was not that luxurious and extravagant as that for the Beijing Olympics, but would have its own characteristics under the elaborate design and thorough arrangement conducted by the host. The veto against that luxurious opening ceremony was actually a practice echoing for the concept of Green World Expo, which would be applied for every corner from the beginning to the end of the Expo, including the construction of exhibition hall, building of exhibition stand and advertisement etc.

  4. World Expo and Exhibition Industry

    Institute of Scientific and Technical Information of China (English)

    Guo Liqin

    2010-01-01

    @@ February 8 witnessed the construction of 2010 World Expo's China Pavilion completed after two years' work. The pavilion, in the shape of an oriental crown,showcases the spirit of traditional Chinese culture. It is significant since all other nation's pavilion constructed only for temporary exhibition, but China's Pavilion will be lasting architecture as the symbol of world civilization. Another similar famous case is Eiffel Tower which was built as the entrance of the world expo held in. 1889.

  5. A New Exhibition in Microcosm

    CERN Multimedia

    2000-01-01

    Sebastien Pelletier explains states of matter to an enthusiastic group of youngsters during the opening of a new exhibition in Microcosm last week. The Fun with Physics workshop will be offered to all 13-14 year olds in school groups visiting CERN this year. The new Microcosm contents have been developed in collaboration with the local teaching community, and cover particles and the forces that act between them.

  6. "Big Science" exhibition at Balexert

    CERN Multimedia

    2008-01-01

    CERN is going out to meet those members of the general public who were unable to attend the recent Open Day. The Laboratory will be taking its "Big Science" exhibition from the Globe of Science and Innovation to the Balexert shopping centre from 19 to 31 May 2008. The exhibition, which shows the LHC and its experiments through the eyes of a photographer, features around thirty spectacular photographs measuring 4.5 metres high and 2.5 metres wide. Welcomed and guided around the exhibition by CERN volunteers, shoppers at Balexert will also have the opportunity to discover LHC components on display and watch films. "Fun with Physics" workshops will be held at certain times of the day. Main hall of the Balexert shopping centre, ground floor, from 9.00 a.m. to 7.00 p.m. Monday to Friday and from 10 a.m. to 6 p.m. on the two Saturdays. Call for volunteers All members of the CERN personnel are invited to enrol as volunteers to help welcom...

  7. Mobile Technologies in Museum Exhibitions

    Directory of Open Access Journals (Sweden)

    Sandra Medić

    2014-10-01

    Full Text Available In order to be up–to–date and give visitors a memorable and unique experience, museums are including usage of digital technologies in their exhibitions. Even though museums in Serbia are very important part of tourism offer, they still have traditional settings that are poorly interpreted. The majority of them have a scientific and historical review which is unattractive for various target groups of visitors and for museums it’s important to continually try out new ways in interpretation of their settings. Because technology continues to rapidly change the way we communicate, cultural institutions should adapt to new ways of communication with their visitors. This paper examines mobile technologies that can be used in museums to give visitors a different experience and transfer the knowledge innovatively. In that way it will be presented the modern concept of presentation of museum exhibitions, focusing on usage of mobile devices through mobile applications and QR codes. The paper provides the broad understanding of usage mobile technologies in museum exhibitions with its advantages and limitations. The research results can help the museums management to improve interpretation and communication with visitors and enrich the visitor experience.

  8. Borneo 2007. Three European Exhibitions

    Directory of Open Access Journals (Sweden)

    Bernard Sellato

    2013-01-01

    Full Text Available The year 2007 appears to have been an exceptionally good one for Borneo in Europe. Two exhibitions were held in France, and one in Switzerland, which prominently featured the big island, its forests, its peoples, its cultures, and its arts. Here a brief review of these three events. Bornéo... Dayak et Punan. Peuples de la forêt tropicale humide, Musée d’Art et d’Archéologie, Laon, France, 25 November 2006 – 11 March 2007 The beautiful city of Laon, only a short distance by train or by car fro...

  9. CERN Permanent exhibitions short version

    CERN Multimedia

    2016-01-01

    Visits Explore by yourself the issues CERN's physicists are trying to solve: given that the entire universe is made of particles, where do they come from? Why do they behave in the way they do? Discover the massive apparatus used by physicists at CERN, like the LHC, and see how each part works. CERN invites the public to discover the mysteries of the Universe and the work of the world's biggest physics laboratory through free of charge guided tours and permanent exhibitions. As a group, with friends, individually, on foot, on your bike, come and discover CERN or explore it virtually. Welcome!

  10. Disposable all-solid-state pH and glucose sensors based on conductive polymer covered hierarchical AuZn oxide.

    Science.gov (United States)

    Kim, Dong-Min; Cho, Seong Je; Cho, Chul-Ho; Kim, Kwang Bok; Kim, Min-Yeong; Shim, Yoon-Bo

    2016-05-15

    Poly(terthiophene benzoic acid) (pTBA) layered-AuZn alloy oxide (AuZnOx) deposited on the screen printed carbon electrode (pTBA/AuZnOx/SPCE) was prepared to create a disposable all-solid-state pH sensor at first. Further, FAD-glucose oxidase (GOx) was immobilized onto the pTBA/AuZnOx/SPCE to fabricate a glucose sensor. The characterizations of the sensor probe reveal that AuZnOx forms a homogeneous hierarchical structure, and that the polymerized pTBA layer on the alloy oxide surface captures GOx covalently. The benzoic acid group of pTBA coated on the probe layer synergetically improved the pH response of the alloy oxide and provide chemical binding sites to enzyme, which resulted in a Nernstian behavior (59.2 ± 0.5 mV/pH) in the pH range of 2-13. The experimental parameters affecting the glucose analysis were studied in terms of pH, temperature, humidity, and interferences. The sensor exhibited a fast response time <1s and a dynamic range between 30 and 500 mg/dL glucose with a detection limit of 17.23 ± 0.32 mg/dL. The reliabilities of the disposable pH and glucose sensors were examined for biological samples.

  11. Enrico Fermi exhibition at CERN

    CERN Document Server

    2002-01-01

    A touring exhibition celebrating the centenary of Enrico Fermi's birth in 1901 will be on display at CERN (Main Building, Mezzanine) from 12-27 September. You are cordially invited to the opening celebration on Thursday 12 September at 16:00 (Main Building, Council Chamber), which will include speechs from: Luciano Maiani Welcome and Introduction Arnaldo Stefanini Celebrating Fermi's Centenary in Documents and Pictures Antonino Zichichi The New 'Centro Enrico Fermi' at Via Panisperna Ugo Amaldi Fermi at Via Panisperna and the birth of Nuclear Medicine Jack Steinberger Fermi in Chicago Valentin Telegdi A Close-up of Fermi and the screening of a documentary video about Fermi: Scienziati a Pisa: Enrico Fermi (Scientists at Pisa: Enrico Fermi) created by Francesco Andreotti for La Limonaia from early film, photographs and sound recordings (In Italian, with English subtitles - c. 30 mins). This will be followed by an aperitif on the Mezz...

  12. Crows spontaneously exhibit analogical reasoning.

    Science.gov (United States)

    Smirnova, Anna; Zorina, Zoya; Obozova, Tanya; Wasserman, Edward

    2015-01-19

    Analogical reasoning is vital to advanced cognition and behavioral adaptation. Many theorists deem analogical thinking to be uniquely human and to be foundational to categorization, creative problem solving, and scientific discovery. Comparative psychologists have long been interested in the species generality of analogical reasoning, but they initially found it difficult to obtain empirical support for such thinking in nonhuman animals (for pioneering efforts, see [2, 3]). Researchers have since mustered considerable evidence and argument that relational matching-to-sample (RMTS) effectively captures the essence of analogy, in which the relevant logical arguments are presented visually. In RMTS, choice of test pair BB would be correct if the sample pair were AA, whereas choice of test pair EF would be correct if the sample pair were CD. Critically, no items in the correct test pair physically match items in the sample pair, thus demanding that only relational sameness or differentness is available to support accurate choice responding. Initial evidence suggested that only humans and apes can successfully learn RMTS with pairs of sample and test items; however, monkeys have subsequently done so. Here, we report that crows too exhibit relational matching behavior. Even more importantly, crows spontaneously display relational responding without ever having been trained on RMTS; they had only been trained on identity matching-to-sample (IMTS). Such robust and uninstructed relational matching behavior represents the most convincing evidence yet of analogical reasoning in a nonprimate species, as apes alone have spontaneously exhibited RMTS behavior after only IMTS training. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Cystamine preparations exhibit anticoagulant activity.

    Science.gov (United States)

    Aleman, Maria M; Holle, Lori A; Stember, Katherine G; Devette, Christa I; Monroe, Dougald M; Wolberg, Alisa S

    2015-01-01

    Transglutaminases are a superfamily of isoenzymes found in cells and plasma. These enzymes catalyze the formation of ε-N-(γ-glutamyl)-lysyl crosslinks between proteins. Cystamine blocks transglutaminase activity and is used in vitro in human samples and in vivo in mice and rats in studies of coagulation, immune dysfunction, and inflammatory disease. These studies have suggested cystamine blocks fibrin crosslinking and has anti-inflammatory effects, implicating transglutaminase activity in the pathogenesis of several diseases. We measured the effects of cystamine on fibrin crosslinking, tissue factor-triggered plasma clot formation and thrombin generation, and coagulation factor enzymatic activity. At concentrations that blocked fibrin crosslinking, cystamine also inhibited plasma clot formation and reduced thrombin generation. Cystamine inhibited the amidolytic activity of coagulation factor XI and thrombin towards chromogenic substrates. These findings demonstrate that cystamine exhibits anticoagulant activity during coagulation. Given the close relationship between coagulation and inflammation, these findings suggest prior studies that used cystamine to implicate transglutaminase activity in disease pathogenesis warrant re-examination.

  14. Cystamine preparations exhibit anticoagulant activity.

    Directory of Open Access Journals (Sweden)

    Maria M Aleman

    Full Text Available Transglutaminases are a superfamily of isoenzymes found in cells and plasma. These enzymes catalyze the formation of ε-N-(γ-glutamyl-lysyl crosslinks between proteins. Cystamine blocks transglutaminase activity and is used in vitro in human samples and in vivo in mice and rats in studies of coagulation, immune dysfunction, and inflammatory disease. These studies have suggested cystamine blocks fibrin crosslinking and has anti-inflammatory effects, implicating transglutaminase activity in the pathogenesis of several diseases. We measured the effects of cystamine on fibrin crosslinking, tissue factor-triggered plasma clot formation and thrombin generation, and coagulation factor enzymatic activity. At concentrations that blocked fibrin crosslinking, cystamine also inhibited plasma clot formation and reduced thrombin generation. Cystamine inhibited the amidolytic activity of coagulation factor XI and thrombin towards chromogenic substrates. These findings demonstrate that cystamine exhibits anticoagulant activity during coagulation. Given the close relationship between coagulation and inflammation, these findings suggest prior studies that used cystamine to implicate transglutaminase activity in disease pathogenesis warrant re-examination.

  15. EU Climate Change Exhibition Held

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>On April 25, the CPAFFC, the China-EU Association (CEUA) and the Delegation of the European Commission to China jointly held the opening ceremony for the EU Exhibition on Climate Change in the CPAFFC. He Luli, former vice chairperson of the NPC Standing Committee and honorary president of the CEUA, Jose Manuel Barroso, president of the European Commission, and Li Jianping, vice president of the CPAFFC, attended the opening ceremony and made speeches. Honorary President He Luli highly praised the achievements made by China and the EU in their longtime cooperation of mutual benefits in various fields including environmental protection. She said, for many years China and EU have both committed to the development of all-round strategic partnership and establishment of a multi-level mechanism of political dialogue. She expressed, with increasing enthusiasm the CEUA would continue to actively carry out nongovernmental exchanges between China and the EU, and promote cooperation between the two sides in the fields of economy, society, environmental protection, science and technology, culture, etc.

  16. Exhibition: Linus Pauling and the Twentieth Century

    CERN Document Server

    2003-01-01

    On April 28 the exhibit Linus Pauling and the Twentieth Century organised by UNIDIR (United Nations Institute for Disarmament Research) and SGI (Soka Gakkai International) as well as with the contributions of CERN and the University of Geneva, opened at the United Nations Office of Geneva. Linus Pauling is the only person to date to have won two unshared Nobel Prizes: Chemistry in 1954 and Peace in 1962. The first was awarded for his landmark research on the nature of the chemical bond and its application in understanding the structure of complex substances. The second one acknowledged his courageous protest against atmospheric nuclear testing and his championship of international peace. The exhibit, for audience of all ages, traces seven decades of Linus Pauling's life and influence on the 20th century. Before starting its European tour at the UNESCO headquarters in Paris, the exhibit opened in 1998 in San Francisco and then travelled within the United-States and to Japan with an attendance of more than one...

  17. Exhibition: Linus Pauling and the Twentieth Century

    CERN Multimedia

    2003-01-01

    On April 28 the exhibit Linus Pauling and the Twentieth Century organised by UNIDIR (United Nations Institute for Disarmament Research) and SGI (Soka Gakkai International) as well as with the contributions of CERN and the University of Geneva, opens at the United Nations Office of Geneva. Linus Pauling is the only person to date to have won two unshared Nobel Prizes: Chemistry in 1954 and Peace in 1962. The first was awarded for his landmark research on the nature of the chemical bond and its application in understanding the structure of complex substances. The second one acknowledged his courageous protest against atmospheric nuclear testing and his championship of international peace. The exhibit, for all ages' audiences, traces seven decades of Linus Pauling's life and influence on the 20th century. Before starting its European tour at the UNESCO headquarters in Paris, the exhibit opened in 1998 in San Francisco and then travelled within the United-States and to Japan with an attendance of more than one m...

  18. Beijing's Convention and Exhibition Industry Maintains Good Momentum

    Institute of Scientific and Technical Information of China (English)

    Xiong Jiuling

    2011-01-01

    @@ In recent years, Beijing's conven-tion and exhibition industry has maintained a good development momentum with expanding scale and improving facilities, becoming an inseparable part of the city's modern service sector.The development of the convention and exhibition industry has played an active role in perfecting the capital's functions, optimizing the industrial structure and enhancing the city's radiation capabilities.

  19. Liu Hong: no trivial on exhibitions

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    To Work for Tomorrow Liu Hong, General Manager of TUTTI Exhibition Service (Xiamen) Co., Ltd, has set up TUTTI Exhibition Service (Xiamen) Co., Ltd in 2001, when exhibition industry firstly appear in Xiamen. Furthermore, the company has developed rapidly in recent years. As Liu Hong regards, exhibition industry, as well as advertisement industry, is an industry filled with challenges and followed

  20. Low temperature biosynthesis of Li2O–MgO–P2O5–TiO2 nanocrystalline glass with mesoporous structure exhibiting fast lithium ion conduction

    DEFF Research Database (Denmark)

    Du, X.Y.; He, W.; Zhang, X.D.

    2013-01-01

    We demonstrate a biomimetic synthesis methodology that allows us to create Li2O–MgO–P2O5–TiO2 nanocrystalline glass with mesoporous structure at lower temperature. We design a ‘nanocrystal-glass’ configuration to build a nanoarchitecture by means of yeast cell templates self-assembly followed by ...

  1. Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Anti-Tumor Activity in Cancer Cells that Display Resistance to Proapoptotic Stimuli: an Investigation of Structure-Activity Relationship and Mechanistic Insight

    Science.gov (United States)

    Lamoral-Theys, Delphine; Andolfi, Anna; Van Goietsenoven, Gwendoline; Cimmino, Alessio; Le Calvé, Benjamin; Wauthoz, Nathalie; Mégalizzi, Véronique; Gras, Thierry; Bruyère, Céline; Dubois, Jacques; Mathieu, Véronique; Kornienko, Alexander; Kiss, Robert; Evidente, Antonio

    2011-01-01

    Twenty-two lycorine-related compounds were investigated for in vitro anti-tumor activity using four cancer cell lines displaying different levels of resistance to pro-apoptotic stimuli and two cancer cell lines sensitive to pro-apoptotic stimuli. Lycorine and six of its congeners exhibited potency in the single-digit micromolar range, while no compound appeared more active than lycorine. Lycorine also displayed the highest potential (in vitro) therapeutic ratio, being at least 15 times more active against cancer than normal cells. Our studies also showed that lycorine exerts its in vitro anti-tumor activity through cytostatic rather than cytotoxic effects. Furthermore, lycorine provided significant therapeutic benefit in mice bearing brain grafts of the B16F10 melanoma model at non-toxic doses. Thus, the results of the current study make lycorine an excellent lead for the generation of compounds able to combat cancers, which are naturally resistant to pro-apoptotic stimuli, such as glioblastoma, melanoma, non-small-cell-lung cancers, metastatic cancers, among others. PMID:19788245

  2. Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.

    Science.gov (United States)

    Lamoral-Theys, Delphine; Andolfi, Anna; Van Goietsenoven, Gwendoline; Cimmino, Alessio; Le Calvé, Benjamin; Wauthoz, Nathalie; Mégalizzi, Véronique; Gras, Thierry; Bruyère, Céline; Dubois, Jacques; Mathieu, Véronique; Kornienko, Alexander; Kiss, Robert; Evidente, Antonio

    2009-10-22

    Twenty-two lycorine-related compounds were investigated for in vitro antitumor activity using four cancer cell lines displaying different levels of resistance to proapoptotic stimuli and two cancer cell lines sensitive to proapoptotic stimuli. Lycorine and six of its congeners exhibited potency in the single-digit micromolar range, while no compound appeared more active than lycorine. Lycorine also displayed the highest potential (in vitro) therapeutic ratio, being at least 15 times more active against cancer than normal cells. Our studies also showed that lycorine exerts its in vitro antitumor activity through cytostatic rather than cytotoxic effects. Furthermore, lycorine provided significant therapeutic benefit in mice bearing brain grafts of the B16F10 melanoma model at nontoxic doses. Thus, the results of the current study make lycorine an excellent lead for the generation of compounds able to combat cancers, which are naturally resistant to proapoptotic stimuli, such as glioblastoma, melanoma, non-small-cell-lung cancers, and metastatic cancers, among others.

  3. VNU Exhibitions Asia: Two factors are crucial

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Reporter: How to appraises the Chinese exhibition industry market? Jime Essink :The Chinese exhibition market will experience a fast growth in the coming years. This will mainly be the result of an increase of international visitors who

  4. Report on Exhibition Industry in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ 1. General Characteristics of Shanghai Exhibitions As the leader of economic development in the Yangtze River Delta,Shanghai has basically formed a certain scale and strength in the aspects of urban transportation, exhibition venues, supporting facilities, service levels, etc.

  5. A ditopic O(4)S(2) macrocycle and its hard, soft, and hard/soft metal complexes exhibiting endo-, exo-, or endo/exocyclic coordination: synthesis, crystal structures, NMR titration, and physical properties.

    Science.gov (United States)

    Ryu, Hyunsoo; Park, Ki-Min; Ikeda, Mari; Habata, Yoichi; Lee, Shim Sung

    2014-04-21

    A 20-membered O4S2 macrocycle (L(2)) was synthesized as a ditopic ligating system toward hard and soft metal ions simultaneously. Five complexes (3-7) of L(2) with different structures and coordination modes, including discrete to infinite forms, mono- to heteronuclear, and endo- to exo- and endo/exocoordination, were prepared and structurally characterized. First, the reaction of L(2) with Pb(ClO4)2·3H2O afforded a typical endocyclic mononuclear perchlorato complex [Pb(L(2))(ClO4)2] (3) in which one lead(II) is surrounded by the macrocycle adopting a "tight and bent" conformation. Meanwhile, the reaction with a softer metal salt AgNO3 resulted in the formation of the dinuclear bis(macrocycle) complex [Ag2(L(2))2(NO3)2] (4) in which two exocyclic silver(I) ions are doubly linked by two nitrate ions. The treatment of L(2) with CuI gave a mixture of the exocyclic monomer complex [Cu(L(2))I] (5) and the exocyclic dimer complex [(Cu2I2)(L(2))2] (6), which were separated manually because of their brick and rhomboid shapes of the crystals, respectively. Furthermore, the reaction of L(2) with a mixture of CuI and NaI afforded a photoluminescent heteronuclear complex [Na2(Cu6I8)(L(2))2(CH3CN)4]n (7) in the endo/exocyclic coordination mode. In this case, the endocyclic sodium(I) complex units are linked by the double-open cubanes-type cluster Cu6I8, yielding a two-dimensional network. The structural and binding properties of the complex of L(2) with silver(I) nitrate in solution were monitored by the NMR titration. Photophysical and thermal properties for complex 7 were also investigated and discussed.

  6. Development Report on Exhibition Industry in Guangzhou

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ Ⅰ. Generat Features of Guangzhou Exhibitions (Ⅰ) Quantity of Exhibitions and Industry Features. Overall, after suf-fering from global financial crisis in 2008 as well as the interference of Beijing Olympic Games and other major events, the exhibition industry in Guangzhou has still not encountered an easy condition in 2009.

  7. Beijing Lack of "Carrier"Exhibition Center

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    An Interview towards Mr. Chu Xiangyin, Vice Chairman of Beijing Subcouncil, CCPIT Reporter: Would you please tell us development of exhibition industry in Beijing? Chu Xiangyin: Beijing Statistical Bureau and us have been designing and analyzing statistical system for exhibition industry from 2003. As the largest exhibition center in Beijing,

  8. Synthesis, structure, and magnetism of a family of heterometallic {Cu2Ln7} and {Cu4Ln12} (Ln = Gd, Tb, and Dy) complexes: the Gd analogues exhibiting a large magnetocaloric effect.

    Science.gov (United States)

    Langley, Stuart K; Moubaraki, Boujemaa; Tomasi, Corrado; Evangelisti, Marco; Brechin, Euan K; Murray, Keith S

    2014-12-15

    The syntheses, structures, and magnetic properties of two heterometallic Cu(II)-Ln(III) (Ln(III) = Gd, Tb, and Dy) families, utilizing triethanolamine and carboxylate ligands, are reported. The first structural motif displays a nonanuclear {Cu(II)2Ln(III)7} metallic core, while the second reveals a hexadecanuclear {Cu(II)4Ln(III)12} core. The differing nuclearities of the two families stem from the choice of carboxylic acid used in the synthesis. Magnetic studies show that the most impressive features are displayed by the {Cu(II)2Gd(III)7} and {Cu(II)4Gd(III)12} complexes, which display a large magnetocaloric effect, with entropy changes -ΔSm = 34.6 and 33.0 J kg(-1) K(-1) at T = 2.7 and 2.9 K, respectively, for a 9 T applied field change. It is also found that the {Cu(II)4Dy(III)12} complex displays single-molecule magnet behavior, with an anisotropy barrier to magnetization reversal of 10.1 K.

  9. Affordances and distributed cognition in museum exhibitions

    DEFF Research Database (Denmark)

    Achiam, Marianne; May, Michael; Marandino, Martha

    2014-01-01

    consistent framework. Here, we invoke the notions of affordance and distributed cognition to explain in a coherent way how visitors interact with exhibits and exhibit spaces and make meaning from those interactions, and we exemplify our points using observations of twelve visitors to exhibits at a natural...... history museum. We show how differences in exhibit characteristics give rise to differences in the interpretive strategies used by visitors in their meaning-making process, and conclude by discussing how the notions of affordance and distributed cognition can be used in an exhibit design perspective....

  10. Syntheses, structures, and magnetic properties of three one-dimensional end-to-end azide/cyanate-bridged copper(II) compounds exhibiting ferromagnetic interaction: new type of solid state isomerism.

    Science.gov (United States)

    Sasmal, Sujit; Sarkar, Sohini; Aliaga-Alcalde, Núria; Mohanta, Sasankasekhar

    2011-06-20

    The work in this paper presents the syntheses, structures, and magnetic properties of three end-to-end (EE) azide/cyanate-bridged copper(II) compounds [Cu(II)L(1)(μ(1,3)-NCO)](n)·2nH(2)O (1), [Cu(II)L(1)(μ(1,3)-N(3))](n)·2nH(2)O (2), and [Cu(II)L(2)(μ(1,3)-N(3))](n) (3), where the ligands used to achieve these species, HL(1) and HL(2), are the tridentate Schiff base ligands obtained from [1 + 1] condensations of salicylaldehyde with 4-(2-aminoethyl)-morpholine and 3-methoxy salicylaldehyde with 1-(2-aminoethyl)-piperidine, respectively. Compounds 1 and 2 crystallize in the monoclinic P2(1)/c space group, while compound 3 crystallizes in the orthorhombic Pbca space group. The metal center in 1-3 is in all cases pentacoordinated. Three coordination positions of the metal center in 1, 2, or 3 are satisfied by the phenoxo oxygen atom, imine nitrogen atom, and morpholine (for 1 and 2) or piperidine (for 3) nitrogen atom of one deprotonated ligand, [L(1)](-) or [L(2)](-). The remaining two coordination positions are satisfied by two nitrogen atoms of two end-to-end bridging azide ligands for 2 and 3 and one nitrogen atom and one oxygen atom of two end-to-end bridging cyanate ligands for 1. The coordination geometry of the metal ion is distorted square pyramidal in which one EE azide/cyanate occupies the apical position. Variable-temperature (2-300 K) magnetic susceptibilities of 1-3 have been measured under magnetic fields of 0.05 (from 2 to 30 K) and 1.0 T (from 30 to 300 K). The simulation reveals a ferromagnetic interaction in all three compounds with J values of +0.19 ± 0.01, +0.79 ± 0.01, and +1.25 ± 0.007 cm(-1) for 1, 2, and 3, respectively. Compound 1 is the sole example of a ferromagnetically coupled EE cyanate-bridged 1-D copper(II) system. In addition, a rare example of supramolecular isomerism and a nice example of magnetic isomerism have been observed and most interestingly a new type of solid state isomerism has emerged as a result of the comparison

  11. Presentation and exhibition activities for promoting theexportof transport services

    Directory of Open Access Journals (Sweden)

    Darya Vladimirovna Nesterova

    2012-03-01

    Full Text Available Development of presentation and exhibition activities is considered as an important factor in providing new competitive advantages at the strategic markets for exporting of transportation services. A specific role for exhibition activities as a factor to overcome market failures arose from imperfect information and incomplete markets is displayed. Exhibitions are considered as a true reflection of most market parameters, as a means to get correct information concerning market capacity and its borders, as an instrument to access to new markets. At the firm level presentation and branding activities should be considered as a modern technology (especially it concerns Russian companies which provide to hold up already existed markets and to conquer new ones. Presentation and branding activities are an effective technology to promote company trade-mark, competitive advantages for market demand increasing. Comparative analysis of the main exhibitions on transport and logistics issues is fulfilled on the data basecollected by authors. Data observes geographical distribution of transport exhibition and exhibition facilities development at several regions for the last years. The analyses allow to revealing a geographical structure of the exhibitions and its distribution by type of transport. The most promising and economically favorable exhibition areas for the promotion of Russian transport services are shown.

  12. Breast cancers from black women exhibit higher numbers of immunosuppressive macrophages with proliferative activity and of crown-like structures associated with lower survival compared to non-black Latinas and Caucasians.

    Science.gov (United States)

    Koru-Sengul, Tulay; Santander, Ana M; Miao, Feng; Sanchez, Lidia G; Jorda, Merce; Glück, Stefan; Ince, Tan A; Nadji, Mehrad; Chen, Zhibin; Penichet, Manuel L; Cleary, Margot P; Torroella-Kouri, Marta

    2016-07-01

    Racial disparities in breast cancer incidence and outcome are a major health care challenge. Patients in the black race group more likely present with an early onset and more aggressive disease. The occurrence of high numbers of macrophages is associated with tumor progression and poor prognosis in solid malignancies. Macrophages are observed in adipose tissues surrounding dead adipocytes in "crown-like structures" (CLS). Here we investigated whether the numbers of CD163+ tumor-associated macrophages (TAMs) and/or CD163+ CLS are associated with patient survival and whether there are significant differences across blacks, non-black Latinas, and Caucasians. Our findings confirm that race is statistically significantly associated with the numbers of TAMs and CLS in breast cancer, and demonstrate that the highest numbers of CD163+ TAM/CLS are found in black breast cancer patients. Our results reveal that the density of CD206 (M2) macrophages is a significant predictor of progression-free survival univariately and is also significant after adjusting for race and for HER2, respectively. We examined whether the high numbers of TAMs detected in tumors from black women were associated with macrophage proliferation, using the Ki-67 nuclear proliferation marker. Our results reveal that TAMs actively divide when in contact with tumor cells. There is a higher ratio of proliferating macrophages in tumors from black patients. These findings suggest that interventions based on targeting TAMs may not only benefit breast cancer patients in general but also serve as an approach to remedy racial disparity resulting in better prognosis patients from minority racial groups.

  13. Investigating Design Research Landscapes through Exhibition

    DEFF Research Database (Denmark)

    Jönsson, Li; Hansen, Flemming Tvede; Mäkelä, Maarit;

    2013-01-01

    What characterizes a design research exhibition compared to a traditional design and art exhibition? How do you show the very materialities of the design experiments as a means for communicating knowledge of research and of practice? How do you present, review and utilize such an exhibition......? With those questions in mind, the intention and challenge for the Nordes 2013 Design Research Exhibition was to expand on current notions of staging research enquires in design research conference contexts. Artefacts, installations, performances, and other materialities that relate to the theme...... of the conference - Experiments in Design Research – were displayed as tools to express and communicate different design research enquires. Through this paper we will describe the Nordes exhibition as a specific case that renders questions visible in relation to how to utilize a design research exhibition...

  14. Artefacts and the performance of an exhibition

    DEFF Research Database (Denmark)

    Svabo, Connie

    2008-01-01

    The article explores the role of mediating artefacts in children's encounters with a museum of natural history. Using actor network theory it explores how a specific artefact shapes the way users relate to exhibited objects and how the artefact guides users' movements in the exhibition. The media...

  15. Encountering Nanotechnology in an Interactive Exhibition

    Science.gov (United States)

    Murriello, Sandra E.; Knobel, Marcelo

    2008-01-01

    This article offers findings from a learning sciences-informed evaluation of a nanoscience and nanotechnology exhibition called Nano-Aventura (NanoAdventure), based on four interactive-collaborative games and two narrated videos. This traveling exhibition was developed in Brazil by the Museu Exploratorio de Ciencias for children and teenagers…

  16. Exhibition Economy Set to Boost City Development

    Institute of Scientific and Technical Information of China (English)

    Li Zhen

    2010-01-01

    @@ Awell-developed exhibition industry is usually regarded as an important cri terion in measuring a city's economic and social development level. In recent years, much attention has been paid to exhibition economy for its positive effect on dining, transportation, tourism, advertising, and shopping.

  17. Science Fiction Exhibits as STEM Gateways

    Science.gov (United States)

    Robie, Samantha

    Women continue to hold less than a quarter of all STEM jobs in the United States, prompting many museums to develop programs and exhibits with the express goal of interesting young girls in scientific fields. At the same time, a number of recent museum exhibits have harnessed the popularity of pop culture and science fiction in order to interest general audiences in STEM subject matter, as well as using the exhibits as springboards to expand or shift mission goals and focus. Because science fiction appears to be successful at raising interest in STEM fields, it may be an effective way to garner the interest of young girls in STEM in particular. This research seeks to describe the ways in which museums are currently using science fiction exhibits to interest young girls in STEM fields and careers. Research focused on four institutions across the country hosting three separate exhibits, and included staff interviews and content analysis of exhibit descriptions, promotional materials, a summative evaluation and supplementary exhibit productions. In some ways, science fiction exhibits do serve young girls, primarily through the inclusion of female role models, staff awareness, and prototype testing to ensure interactives are attractive to girls as well as to boys. However, STEM appears to be underutilized, which may be partly due to a concern within the field that the outcome of targeting a specific gender could be construed as "stereotyping".

  18. Encountering Nanotechnology in an Interactive Exhibition

    Science.gov (United States)

    Murriello, Sandra E.; Knobel, Marcelo

    2008-01-01

    This article offers findings from a learning sciences-informed evaluation of a nanoscience and nanotechnology exhibition called Nano-Aventura (NanoAdventure), based on four interactive-collaborative games and two narrated videos. This traveling exhibition was developed in Brazil by the Museu Exploratorio de Ciencias for children and teenagers…

  19. Exhibition-based Immersive Performance Environments

    DEFF Research Database (Denmark)

    Svabo, Connie

    2017-01-01

    Art”. This exhibition concept has been awarded the prize “Bikubens Udstillings Visionspris” 2016 for its innovative take on exhibitions. In the Sister’s Academy Boarding School visitors ‘move into’ and inhabit an exhibition for a longer period of time, for example 24 or 48 hours. This radically breaks...... with the conventional 1½ hour duration of museum visits and creates new possibilities of and challenges for presence in museums. The paper analyzes exhibition experience as an engagement, which with its immersive and emergent qualities, radically breaks with visual modes of appreciation. The visitor does not ‘stand...... to the everyday and to conventional modes of being, interaction and communication. The exhibition thus becomes a space of potential; a critical and utopian space for trying out new forms of being and new modes of engagement. Theoretically the paper focuses on Berleant’s environmental aesthetics and the notion...

  20. The Culture of Exhibitions and Conservation

    Directory of Open Access Journals (Sweden)

    Dimitrios Doumas

    2013-11-01

    Full Text Available The article reflects on temporary exhibitions from a theoretical as well as practical perspective. Regarded as a particularly effective mass-communication medium, exhibitions have a dual nature: they are scholarly undertakings, bringing off a curator’s vision and, simultaneously, they are projects with economic implications that need to be well managed and administered. The role of conservation in the making of temporary exhibitions, either in-house or touring, is here discussed in relation to how work is planned and prioritized as well as how time is managed and staff is allocated. Reference to weaknesses that lessen the crucial input of conservation in the decision-making process is also made. Much of the debate, which focuses on art exhibitions, concerns practicalities encountered in a private museum that extend from the very early stages of selecting objects for display to the mounting of an exhibition.

  1. High Quality Virtual Reality for Architectural Exhibitions

    DEFF Research Database (Denmark)

    Kreutzberg, Anette

    2016-01-01

    This paper will summarise the findings from creating and implementing a visually high quality Virtual Reality (VR) experiment as part of an international architecture exhibition. It was the aim to represent the architectural spatial qualities as well as the atmosphere created from combining natural...... and artificial lighting in a prominent not yet built project. The outcome is twofold: Findings concerning the integration of VR in an exhibition space and findings concerning the experience of the virtual space itself. In the exhibition, an important aspect was the unmanned exhibition space, requiring the VR...... and quantitative methods at two different occasions and setups after the exhibition, both showing a high degree of immersion and experience of reality....

  2. Holland at CERN – Industrial exhibition

    CERN Multimedia

    GS Department

    2010-01-01

    Sponsored by EVD, an agency of the Dutch Ministry of the Economy From 8 to 11 November 2010 Industrial Exhibition Administration Building Bldg. 61 9-00 - 17-30 Twenty seven companies will present their latest technology at the industrial exhibition "Holland at CERN". Dutch industry will exhibit products and technologies which are related to the field of particle physics. Individual interviews will take place directly at the stands in the Main Building. The firms will contact relevant users/technicians but any user wishing to make contact with a particular firm is welcome to use the contact details which are available from each departmental secretariat or at the following URL: http://gs-dep.web.cern.ch/gs-dep/groups/sem/ls/Industrial_Exhibitions.htm#Industrial_exhibitions You will find the list of exhibitors below. LIST OF EXHIBITORS: Schelde Exotech Vernooy BV Triumph Group INCAA Computers DeMaCo Holland bv TNO Science & Industry Janssen Precision Engi...

  3. A mini-exhibition with maximum content

    CERN Multimedia

    Laëtitia Pedroso

    2011-01-01

    The University of Budapest has been hosting a CERN mini-exhibition since 8 May. While smaller than the main travelling exhibition it has a number of major advantages: its compact design alleviates transport difficulties and makes it easier to find suitable venues in the Member States. Its content can be updated almost instantaneously and it will become even more interactive and high-tech as time goes by.   The exhibition on display in Budapest. The purpose of CERN's new mini-exhibition is to be more interactive and easier to install. Due to its size, the main travelling exhibition cannot be moved around quickly, which is why it stays in the same country for 4 to 6 months. But this means a long waiting list for the other Member States. To solve this problem, the Education Group has designed a new exhibition, which is smaller and thus easier to install. Smaller maybe, but no less rich in content, as the new exhibition conveys exactly the same messages as its larger counterpart. However, in the slimm...

  4. Design of contemporary art exhibitions - a struggle or an embracement?

    DEFF Research Database (Denmark)

    Schwarzbart, Judith

    the individual works together (in liniear or non-liniear structures). Finally, the insitutuion has its guidelines (corporate identity), museum pedagogs have their method and ideas, etc. This paper will address the use of exhibition design in relation to contemporary art and will discuss a number of examples...

  5. High Quality Virtual Reality for Architectural Exhibitions

    DEFF Research Database (Denmark)

    Kreutzberg, Anette

    2016-01-01

    This paper will summarise the findings from creating and implementing a visually high quality Virtual Reality (VR) experiment as part of an international architecture exhibition. It was the aim to represent the architectural spatial qualities as well as the atmosphere created from combining natural...... and artificial lighting in a prominent not yet built project. The outcome is twofold: Findings concerning the integration of VR in an exhibition space and findings concerning the experience of the virtual space itself. In the exhibition, an important aspect was the unmanned exhibition space, requiring the VR...... experience to be self-explanatory. Observations of different visitor reactions to the unmanned VR experience compared with visitor reactions at guided tours with personal instructions are evaluated. Data on perception of realism, spatial quality and light in the VR model were collected with qualitative...

  6. Footprints of China Auto Internatienal Exhibition Tour

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ November 2008,the Sixth China Auto International(Algeria & Egypt)Exhibition Tour is ready.Since the first session was held in 1995,the Chinese auto enterprises have been to Vietnam,Cambodia,Syria,and Russian.

  7. France at CERN – Industrial exhibition

    CERN Multimedia

    FP Department

    2012-01-01

    Industrial Exhibition Administration Building Bldg 61 – 1st Floor Tuesday 27 March: 9 a.m. – 5.30 p.m. Wednesday 28 March: 9 a.m. – 2 p.m.   About thirty French companies are presenting their latest technological advances during the industrial exhibition "France at CERN", featuring products and technologies specifically related to CERN activities. Individual B2B meetings can be organized with the sales and technical representatives of participating firms and will take place at either the companies’ exhibition stands or in conference rooms in the Main Building. Individuals wishing to make contact with one or more companies must use the contact details available from each secretariat of department or by using this link. B2B meetings will be coordinated by UBIFRANCE. You will also find the list of exhibiting and participating companies online here. This event is sponsored by the French subsidiary of RS Components, the most important distri...

  8. 49 CFR 250.2 - Required exhibits.

    Science.gov (United States)

    2010-10-01

    ... and detail for Class II railroads. (14) As Exhibit 14, a statement showing actual cash balance at the beginning of each month and the actual cash receipts and disbursements during each month of the current...

  9. Exhibition 2004: Never-falling Stand

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Another year for reform and development Reform and development, key words and melodies for present life, may reflect future changes definitely. Rapid progress of convention & exhibition industry undoubtedly predicates future development of this industry in China.

  10. Communicating Complex Sciences by Means of Exhibitions

    Science.gov (United States)

    Schneider, S.

    2011-12-01

    Earth Sciences will have to take over the leading role in global sustainable policy and in discussions about climate change. Efforts to raise attention within the politically responsible communities as well as in the public are getting more and more support by executive and advisory boards all over the world. But how can you successfully communicate complex sciences? For example, to start communication about climate change, the first step is to encourage people to be concerned about climate change. After that, one has to start thinking about how to present data and how to include the presented data into an unprejudiced context. Therefore, the communication toolbox offers various methods to reach diverse audiences. The R&D programme GEOTECHNOLOGIEN conducts roving exhibitions as one of its most successful communication tools. With roving exhibitions GEOTECHNOLOGIEN is able to get in touch with different audiences at once. The main purpose and theme of these exhibitions is to convey the everyday means of climate change to the visitors. It is within the responsibility of science to communicate the effects of a phenomenon like climate change as well as the impact of research results to the everyday life of people. Currently, a GEOTECHNOLOGIEN roving exhibition on remote sensing with satellites deals with various issues of environmental research, including a chapter on climate change. By following the 3M-concept (Meaning - Memorable - Moving), exhibitions allow to connect the visitors daily environment and personal experiences with the presented issues and objects. Therefore, hands-on exhibits, exciting multimedia effects and high-tech artefacts have to be combined with interpretive text elements to highlight the daily significance of the scientific topics and the exhibition theme respectively. To create such an exhibition, strong conceptual planning has to be conducted. This includes the specification of stern financial as well as time wise milestones. In addition

  11. Reaching the Public through Traveling Exhibitions

    Science.gov (United States)

    Dusenbery, P. B.; Harold, J. B.; Morrow, C. A.

    2004-11-01

    The Space Science Institute (SSI) of Boulder, Colorado has recently developed two museum exhibits called Alien Earths and MarsQuest. It has just started to develop another exhibit called Giant Planets. These exhibitions provide research scientists the opportunity to engage in a number of activities that are vital to the success of these major outreach programs. Alien Earths was developed in partnership with various research missions. The focus of the presentation will be on MarsQuest and Giant Planets. MarsQuest is a 5000 square-foot, \\$3M, traveling exhibition that is now touring the country. The exhibit's second 3-year tour will enable millions of Americans to share in the excitement of the scientific exploration of Mars and learn more about their own planet in the process. The associated planetarium show and education program will also be described, with particular emphasis on workshops to orient museum staff (e.g. museum educators and docents) and workshops for master educators near host museums and science centers. The workshops make innovative connections between the exhibition's interactive experiences and lesson plans aligned with the National Science Education Standards. These exhibit programs are good models for actively involving scientists and their discoveries to help improve informal science education in the museum community and for forging a stronger connection between formal and informal education. The presentation will also discuss how Giant Planets, a proposed 3500 square-foot traveling exhibition on the mysteries and discoveries of the outer planets, will be able to take advantage of the connections and resources that have been developed by the MarsQuest project.

  12. An Astrobiology Microbes Exhibit and Education Module

    Science.gov (United States)

    Lindstrom, Marilyn M.; Allen, Jaclyn S.; Stocco, Karen; Tobola, Kay; Olendzenski, Lorraine

    2001-01-01

    Telling the story of NASA-sponsored scientific research to the public in exhibits is best done by partnerships of scientists and museum professionals. Likewise, preparing classroom activities and training teachers to use them should be done by teams of teachers and scientists. Here we describe how we used such partnerships to develop a new astrobiology augmentation to the Microbes! traveling exhibit and a companion education module. "Additional information is contained in the original extended abstract."

  13. When Do Children Exhibit a "Yes" Bias?

    Science.gov (United States)

    Okanda, Mako; Itakura, Shoji

    2010-01-01

    This study investigated whether one hundred and thirty-five 3- to 6-year-old children exhibit a yes bias to various yes-no questions and whether their knowledge status affects the production of a yes bias. Three-year-olds exhibited a yes bias to all yes-no questions such as "preference-object" and "knowledge-object" questions pertaining to…

  14. Exhibition by Gozitan artist Mark Sagona

    OpenAIRE

    Calleja, Joseph

    2004-01-01

    Mark Sagona's exhibition, entitled "Recent Insights" was held at the Banca Giuratale in Victoria, Gozo between the 24th January and the 8th February 2004. It brought together twenty-four paintings, all produced in 2003 and the majority of which were realised in oil on canvas. The exhibition was curated by Dr Joseph Paul Cassar, and inaugurated by the Minister for Gozo, the Hon. Giovanna Debono.

  15. [All-Russian hygienic exhibitions and museums].

    Science.gov (United States)

    Kuzybaeva, M P

    2011-01-01

    The material about the popularization of hygiene and health education in Russia in the second half of the 19th century to early 20th century through exhibition and museum activities has been collected for the first time and analyzed in the paper. The role of scientists and scientific medical societies in this process is noted. The significance of museum and exhibition activities in this area for the development of medical science is defined.

  16. Evaluating Education and Science in the KSC Visitor Complex Exhibits

    Science.gov (United States)

    Erickson, Lance K.

    2000-01-01

    The continuing development of exhibits at the Kennedy Space Center's Visitor Complex is an excellent opportunity for NASA personnel to promote science and provide insight into NASA programs and projects for the approximately 3 million visitors that come to KSC annually. Stated goals for the Visitor Complex, in fact, emphasize science awareness and recommend broadening the appeal of the displays and exhibits for all age groups. To this end, this summer project seeks to evaluate the science content of planned exhibits/displays in relation to these developing opportunities and identify specific areas for enhancement of existing or planned exhibits and displays. To help expand the educational and science content within the developing exhibits at the Visitor Complex, this project was structured to implement the goals of the Visitor Center Director. To accomplish this, the exhibits and displays planned for completion within the year underwent review and evaluation for science content and educational direction. Planning emphasis for the individual displays was directed at combining the elements of effective education with fundamental scientific integrity, within an appealing format.

  17. Curated exhibitions and Australian art history

    Directory of Open Access Journals (Sweden)

    Catherine De Lorenzo

    2011-06-01

    Full Text Available Australian Art history in all it guises has tended to bypass the impact of contemporary curated exhibitions on shaping the discipline. Yet an examination of a cluster of key contemporary exhibitions from the early 1970s onwards reveals their significance for the history of art in Australia. They reflect institutional judgements behind the selection, research and display the work of artists as well as the reception of such work by the public, artists, art critics and art historians. This is especially so in the last decades of the 20th century and the first decade of the 21st, as the country underwent major cultural changes. This paper focuses on selected exhibitions of Australian art from 1968 to 2008 and indicates how exhibitions also constitute a major form of contemporary Australian art historiography. As this period coincides with a transformation in the way exhibitions were funded, it also begins to investigate the question of the long term impact of public funding of the arts.

  18. CERN exhibition a big hit in Bulgaria

    CERN Multimedia

    2005-01-01

    The first CERN exhibition in Bulgaria attracted many visitors. In the first ever CERN exhibition to be held in Bulgaria, over 1,400 visitors, many of them students and young physicists, visited the 10-day event in Sofia. The CERN mini-exhibition took place at the National Earth and Mankind Museum between 8 and 17 November. Permanently staffed by young physicists from Sofia University, there were exhibits on display about research activities at CERN, as well as four additional posters describing Bulgaria's participation. The inauguration took place on the morning of 8 November in the presence of the Vice-Minister for Science and Education, Mrs. Vanya Dobreva, and some 200 guests. A series of short speeches were followed by a visit to the exhibition. CERN's representative at the event, Ray Lewis, was then asked by Professor Matey Mateev, President of the Union of Physicists in Bulgaria, to say a few words on behalf of the Organization. Numerous journalists were also present at the inauguration. A painting enti...

  19. The Gravity- Powered Calculator, a Galilean Exhibit

    Science.gov (United States)

    Cerreta, Pietro

    2014-04-01

    The Gravity-Powered Calculator is an exhibit of the Exploratorium in San Francisco. It is presented by its American creators as an amazing device that extracts the square roots of numbers, using only the force of gravity. But if you analyze his concept construction one can not help but recall the research of Galileo on falling bodies, the inclined plane and the projectile motion; exactly what the American creators did not put into prominence with their exhibit. Considering the equipment only for what it does, in my opinion, is very reductive compared to the historical roots of the Galilean mathematical physics contained therein. Moreover, if accurate deductions are contained in the famous study of S. Drake on the Galilean drawings and, in particular on Folio 167 v, the parabolic paths of the ball leaping from its launch pad after descending a slope really actualize Galileo's experiments. The exhibit therefore may be best known as a `Galilean calculator'.

  20. The exploration of the exhibition informatization

    Science.gov (United States)

    Zhang, Jiankang

    2017-06-01

    The construction and management of exhibition informatization is the main task and choke point during the process of Chinese exhibition industry’s transformation and promotion. There are three key points expected to realize a breakthrough during the construction of Chinese exhibition informatization, and the three aspects respectively are adopting service outsourcing to construct and maintain the database, adopting advanced chest card technology to collect various kinds of information, developing statistics analysis to maintain good cutomer relations. The success of Chinese exhibition informatization mainly calls for mature suppliers who can provide construction and maintenance of database, the proven technology, a sense of data security, advanced chest card technology, the ability of data mining and analysis and the ability to improve the exhibition service basing on the commercial information got from the data analysis. Several data security measures are expected to apply during the process of system developing, including the measures of the terminal data security, the internet data security, the media data security, the storage data security and the application data security. The informatization of this process is based on the chest card designing. At present, there are several types of chest card technology: bar code chest card; two-dimension code card; magnetic stripe chest card; smart-chip chest card. The information got from the exhibition data will help the organizers to make relevant service strategies, quantify the accumulated indexes of the customers, and improve the level of the customer’s satisfaction and loyalty, what’s more, the information can also provide more additional services like the commercial trips, VIP ceremonial reception.

  1. Exhibits in libraries a practical guide

    CERN Document Server

    Brown, Mary E

    2005-01-01

    "Ccomprehensive...detailed"--Booklist; "thoroughly reseached...highly recommended"--Journal of Access Services. Library exhibits are more than entertainment for patrons. They can inspire and educate, stimulate an interest that can be explored in a book, or attract visitors who otherwise wouldn't stop by. Displays are also an opportunity for a library to put its creative foot forward or help patrons navigate the facility itself. This comprehensive "how-to" includes everything a librarian or staff member needs to know to put on an exhibit, from hatching ideas to evaluating the end result. Illustrations and photographs show practical methods of planning, labeling and displaying.

  2. How do exhibition visitors describe aesthetic qualities?

    DEFF Research Database (Denmark)

    Thomsen, Bente Dahl; Ravn, Anders Peter

    2007-01-01

    In this investigation, visitors to an art and design exhibition have used an interactive computer program to express the qualities they consider important for an art or design object (artefact). They have then used the program with their individually selected qualities to assess the artefacts. In...

  3. Autoimmune pancreatitis exhibiting multiple mass lesions.

    Science.gov (United States)

    Shiokawa, Masahiro; Kodama, Yuzo; Hiramatsu, Yukiko; Kurita, Akira; Sawai, Yugo; Uza, Norimitsu; Watanabe, Tomohiro; Chiba, Tsutomu

    2011-09-01

    Our case is a first report of autoimmune pancreatitis with multiple masses within the pancreas which was pathologically diagnosed by endoscopic ultrasound-guided fine needle aspiration and treated by steroid. The masses disappeared by steroid therapy. Our case is informative to know that autoimmune pancreatitis sometimes exhibits multiple masses within the pancreas and to diagnose it without unnecessary surgery.

  4. Autoimmune Pancreatitis Exhibiting Multiple Mass Lesions

    Directory of Open Access Journals (Sweden)

    Masahiro Shiokawa

    2011-09-01

    Full Text Available Our case is a first report of autoimmune pancreatitis with multiple masses within the pancreas which was pathologically diagnosed by endoscopic ultrasound-guided fine needle aspiration and treated by steroid. The masses disappeared by steroid therapy. Our case is informative to know that autoimmune pancreatitis sometimes exhibits multiple masses within the pancreas and to diagnose it without unnecessary surgery.

  5. CERN exhibition wins yet another design prize

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    The “Universe of Particles” exhibition in CERN’s Globe wins the silver design prize from the German direct business communications association FAMAB.   Not only do tens of thousands of people visit the “Universe of Particles” exhibition each year, but juries for design prizes are crossing its threshold more and more frequently too. In 2011 alone it claimed 8 awards, including winning outright the 2011 Annual Multimedia award, the iF Communication Design for Corporate Architecture award and the Modern Decoration Media award (the Bulletin already reported on some of these in July 2011). The FAMAB award is the latest to join the prestigious list. The jury of FAMAB’s “ADAM 2011” award was particularly impressed by the hands-on nature of the exhibition, which encourages visitors to get interested in science. They also appreciated the way that the space in the Globe is not just a container for the exhibits, but itself ...

  6. Comic Strips to Accompany Science Museum Exhibits

    Science.gov (United States)

    Chung, Beom Sun; Park, Eun-mi; Kim, Sang-Hee; Cho, Sook-kyoung; Chung, Min Suk

    2016-01-01

    Science museums make the effort to create exhibits with amusing explanations. However, existing explanation signs with lengthy text are not appealing, and as such, visitors do not pay attention to them. In contrast, conspicuous comic strips composed of simple drawings and humors can attract science museum visitors. This study attempted to reveal…

  7. 18 CFR 50.7 - Applications: exhibits.

    Science.gov (United States)

    2010-04-01

    ... data that represent system operating conditions. (i) Exhibit I—Project Cost and Financing. (1) A statement of estimated costs of any new construction or modification. (2) The estimated capital cost and...) Provide all files to model normal, single contingency, multiple contingency, and special...

  8. 32 CFR 705.24 - Exhibits.

    Science.gov (United States)

    2010-07-01

    ..., or similar events. Also included are general purpose displays in public buildings or public locations... support local Navy recruiters. Requests for exhibits for community relations events will be considered... event). (2) The office of the Assistant Secretary of Defense (Public Affairs) is the approving authority...

  9. 18 CFR 34.4 - Required exhibits.

    Science.gov (United States)

    2010-04-01

    ... Cash Flows must be in the form prescribed for the “Statement of Cash Flows” of the FERC Form No. 1... Cash Flows and Computation of Interest Coverage on an actual basis and a pro forma basis for the most... the statement of corporate purposes from its articles of incorporation. (b) Exhibit B. A copy of all...

  10. CCPIT Machinery Exhibition Succeeded in Kuala Lumpur

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

      From August 18 to 20, 2005, China Council for the Promotion of International Trade(CCPIT) held China Machinery and Electronics Trade Exhibition, CME 2005 in Kuala Lumpur, the capital of Malaysia on behalf of China, a good job has been done.……

  11. CCPIT Machinery Exhibition Succeeded in Kuala Lumpur

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ From August 18 to 20, 2005, China Council for the Promotion of International Trade(CCPIT) held China Machinery and Electronics Trade Exhibition, CME 2005 in Kuala Lumpur, the capital of Malaysia on behalf of China, a good job has been done.

  12. Exhibition Ethics - An Overview of Major Issues

    Directory of Open Access Journals (Sweden)

    Andromache Gazi

    2014-05-01

    Full Text Available Museum ethics are about value judgements. In making such judgements museum personnel is constantly valuing one option over another. This holds true for every aspect of museum work; from collecting policies and conservation to store priorities and exhibition. In recent decades there has been a growing concern in addressing ethical issues in museums as museum workers have developed cultural sensitivity and social responsiveness to a degree unseen before. Most codes of ethics urge museums to give appropriate consideration to represented groups or beliefs. In light of this, it has been recognised that exhibition of sensitive material, for example, must be done with great tact and respect for the feelings of religious, ethnic or other groups represented. Another issue concerns the display of unprovenanced material and repatriation. Yet, these are not the only ethical issues which exhibition developers are faced with. As museum workers we should constantly be reminded that exhibitions are active agents in the construction of knowledge. This paper discusses the hidden assumptions on which museum presentation and interpretation are often based. Decisions about what to include and what to exclude, what is valued and what is not, the means of presentation, language, and so on, all lead to presentational styles which may shape the public’s perception in unintended ways.

  13. Retrospect of China International Auto Exhibition Tours

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ "Fengfan Cup" the Frist China International Auto Exhibition Tour In 1995, the first session gathered 28 national motorcycles and autos from four big groups---China North Industries Group Corporation, China Aviation Industry Corporation, China Aerospace Science and Industry Cooperation and PLA General Logistics Department.

  14. Do Online Students Exhibit Different Learning Styles?

    Science.gov (United States)

    Hausler, Joel; Sanders, John W.; Young, Barbara

    2007-01-01

    Do online students exhibit different learning styles from onsite students; and if so, what accommodations relating to learning style differences may be made for online students? Our ideas of best practices within this area have been evolving to keep up with our students. Various tactics have been used to make sure students understand what kinds of…

  15. Do Online Students Exhibit Different Learning Styles

    Science.gov (United States)

    Hausler, Joel; Sanders, John W.; Young, Barbara

    2007-01-01

    We examined the relationship between learning styles and student type. This research seeks to examine if online students exhibit different learning styles from onsite students; and, if so, what accommodations relating to learning style differences may be made for online students? Students (N = 80) were asked to complete an online survey in order…

  16. The palaeontological exhibition: a venue for dialogue.

    Science.gov (United States)

    Murriello, Sandra

    2015-01-01

    Understanding the dialogue between museums and their visitors enables museums to subsist, undergo transformations and become consolidated as socially valued cultural venues. The Museo de La Plata (Argentina) was created in the late nineteenth century as a natural history museum, and this study shows that currently the museum is valued socially as a venue for family leisure and education, at which people make sense to the objects exhibited through characteristics conferred upon them by both the institution and the visitor. Nevertheless, such dialogue is somehow affected by the museographic proposal and the public interpretation of the institutional narrative, which could be analysed within the frame of contextual learning. As a consequence, the evolutionary idea that the museum aims to communicate is distorted by the public. This article highlights the importance of considering the visitors' interpretations when planning museum exhibitions, a perspective that has been rather absent in the Argentinian museums.

  17. Exhibition: Women and Sciences by Fiami

    CERN Multimedia

    Globe Info

    2011-01-01

    The 19-panel exhibition is on display at CERN's Microcosm from Monday to Saturday from 10.00 a.m. to 5.00 p.m.   Marie Curie won the Nobel Prize for Chemistry one hundred years ago. She is the only woman ever to win two Nobel Prizes, which is a testament to her remarkable work. But throughout history, women have played a role in science either in their own right or alongside other scientists. In this special exhibition, the comic-strip artist Fiami takes a look back at the relationship between women and science through his portraits of Mileva Einstein, Marie-Anne Lavoisier and, of course, Marie Curie. Fiami has recently published an entire album devoted to Marie Curie. Texts in French All ages - Entrance free Femmes et Sciences is on display at Microcosm: From Wednesday 21 September 2011 to Tuesday 20 December 2011.

  18. Active Cyber Defense Dynamics Exhibiting Rich Phenomena

    CERN Document Server

    Zheng, Ren; Xu, Shouhuai

    2016-01-01

    The Internet is a man-made complex system under constant attacks (e.g., Advanced Persistent Threats and malwares). It is therefore important to understand the phenomena that can be induced by the interaction between cyber attacks and cyber defenses. In this paper, we explore the rich phenomena that can be exhibited when the defender employs active defense to combat cyber attacks. To the best of our knowledge, this is the first study that shows that {\\em active cyber defense dynamics} (or more generally, {\\em cybersecurity dynamics}) can exhibit the bifurcation and chaos phenomena. This has profound implications for cyber security measurement and prediction: (i) it is infeasible (or even impossible) to accurately measure and predict cyber security under certain circumstances; (ii) the defender must manipulate the dynamics to avoid such {\\em unmanageable situations} in real-life defense operations.

  19. CERN's new microcosm exhibition is now open

    CERN Multimedia

    2016-01-01

    After a major revamp in 2015, CERN’s microcosm exhibition is once again open to visitors. The exhibition is free and open to all without reservation and visitors are encouraged to share their #microcosm @CERN experiences on social media. Read more: http://cern.ch/go/7HWC -Producer- CERN Video Productions -Director- Kate Kahle -Camera- indissoluble.com and Julien Ordan -Editor- Julien Ordan -Infography- Daniel Dominguez Noemi Caraban -Music- “Light Years” by Stellardrone http://freemusicarchive.org/music/Ste... You can follow us on: cern.ch youtube.com/cerntv google.com/+CERN facebook.com/cern twitter.com/cern/ linkedin.com/company/cern instagram.com/cern Copyright © 2016 CERN. Terms of use: http://copyright.web.cern.ch/

  20. Ikuo Hirayama Painting Exhibition Held in Beijing

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>To celebrate the 30th anniversary of the signing of the Sino-Japanese Peace and Friendship Treaty, the Ikuo Hirayama Painting Exhibition jointly sponsored by the China-Japan Friendship Association (CJFA), the China International Culture Association (CICA) and the Japan-China Friendship Association (JCFA), was held in the National Art Museum of China from April 17 to 26. At the invitation of the CJFA, Tomiichi Murayama, former Japanese prime minister, and Ikuo Hirayama, president of the JCFA and famous painter, who led a delegation of over 200 people of various circles, paid a visit to China to attend the opening ceremony of the exhibition and take part in the relevant activities from April 16 to 20.

  1. LHC INAUGURATION, LHC Fest highlights: exhibition time!

    CERN Multimedia

    2008-01-01

    David Gross, one of the twenty-one Nobel Laureates who have participated in the project.Tuesday 21 October 2008 Accelerating Nobels Colliding Charm, Atomic Cuisine, The Good Anomaly, A Quark Somewhere on the White Paper, Wire Proliferation, A Tale of Two Liquids … these are just some of the titles given to artworks by Physics Nobel Laureates who agreed to make drawings of their prize-winning discoveries (more or less reluctantly) during a special photo session. Science photographer Volker Steger made portraits of Physics Nobel Laureates and before the photo sessions he asked them to make a drawing of their most important discovery. The result is "Accelerating Nobels", an exhibition that combines unusual portraits of and original drawings by twenty-one Nobel laureates in physics whose work is closely related to CERN and the LHC. This exhibition will be one of the highlights of the LHC celebrations on 21 October in the SM18 hall b...

  2. Pingyao Traditional Cultural Exhibition Mounted in France

    Institute of Scientific and Technical Information of China (English)

    Ni; Yuan

    2014-01-01

    <正>On the initiative of Provins,a commune in the Nord Department of Northern France and a friendship city of Pingyao in Shanxi Province,an exhibition of Pingyao traditional cultural and art works was staged from June 14 to 17.On display in the ancient SaintQuiriace Collegiate Church were 40 artworks characteristic of the traditional folk art of North China including old photos of Pingyao,calligraphic works,paintings,paper-cut,embroidery and shadow puppets.

  3. Cinema Film Distribution and Exhibition in Ireland

    OpenAIRE

    O'Donnell, Damien

    1992-01-01

    This study of cinema film distribution and exhibition practices In Ireland examines key aspects of the Industry: firstly, the basic mechanics of the Industry and Its operations: secondly, the various alignments between exhibitors and distributors and consequences of those alignments: thirdly, the impact of the arrival of British multiplex companies: fourthly, the costs of film censorship; and finally, the idea of an 'art-house' circuit In Ireland.

  4. PLATE: Product Lifetimes And The Environment Exhibition

    OpenAIRE

    Hanson, Maria

    2015-01-01

    The PLATE (Product Lifetimes And The Environment) Exhibition explored critical themes related to how long products last in contemporary society. The topic of product longevity is examined in innovative ways through prototypes, objects, artefacts, posters, photographs and films produced by designers, social businesses, artists, researchers, lecturers and students.\\ud \\ud Featuring household products, furniture, lighting, fashion, jewellery and artworks, this collection of visual work embraced ...

  5. Exhibition: Dialogue between Science and religion

    CERN Multimedia

    2001-01-01

    Can the theory of the Big Bang reached by physicists and the concept of creation beloved of religion ever be reconciled? The two approaches have at least one point in common: they do not provide a final answer to the mysteries of the birth of the Universe. And this means that dialogue is alays possible between the two. It is to show the potential of such an exchange that Geneva's Société Evangélique organization is opening an exhibition under the title 'Big Bang and Creation', at the Planète Charmilles shopping centre, to run from 19 to 30 March. View of the 'Big Bang and Creation' exhibition. The exhibition is divided into three sections, showing the views of the scientist and those of the believer without setting them up in opposition to one another. In the first section, under a representation of the vault of heaven, the visitor will discover the different ideas explaining the birth of the Universe: Genesis and the Big Bang, and the different dominant theories ...

  6. Synchronization in multicell systems exhibiting dynamic plasticity

    Indian Academy of Sciences (India)

    C Suguna; Somdatta Sinha

    2008-08-01

    Collective behaviour in multicell systems arises from exchange of chemicals/signals between cells and may be different from their intrinsic behaviour. These chemicals are products of regulated networks of biochemical pathways that underlie cellular functions, and can exhibit a variety of dynamics arising from the non-linearity of the reaction processes. We have addressed the emergent synchronization properties of a ring of cells, diffusively coupled by the end product of an intracellular model biochemical pathway exhibiting non-robust birhythmic behaviour. The aim is to examine the role of intercellular interaction in stabilizing the non-robust dynamics in the emergent collective behaviour in the ring of cells. We show that, irrespective of the inherent frequencies of individual cells, depending on the coupling strength, the collective behaviour does synchronize to only one type of oscillations above a threshold number of cells. Using two perturbation analyses, we also show that this emergent synchronized dynamical state is fairly robust under external perturbations. Thus, the inherent plasticity in the oscillatory phenotypes in these model cells may get suppressed to exhibit collective dynamics of a single type in a multicell system, but environmental influences can sometimes expose this underlying plasticity in its collective dynamics.

  7. Art exhibit focuses on African astronomy

    Science.gov (United States)

    Showstack, Randy

    2012-07-01

    Connections between Africans and astronomy are the focus of a new exhibition in the National Museum of African Art in Washington, D. C. "African Cosmos: Stellar Arts," which includes artwork, cultural items, and scientific displays from ancient to contemporary times, is the first major exhibit "that brings together arts and science focused on Africa's contribution to keen observations of the heavens over time," curator Christine Mullen Kreamer said at a 20 June news briefing. Among the exhibit's nearly 100 objects are an ancient Egyptian mummy board that includes a representation of the sky goddess Nut, sculptures by the Dogon people of Mali depicting figures in relation to the cosmos, a video that uses data from two square degrees of the Hubble Space Telescope Cosmic Evolution Survey, and a nearly floor-to-ceiling "Rainbow Serpent" constructed of plastic containers by Benin artist Hazoume. An untitled acrylic painting (Figure 1) by South African Gavin Jantjes evokes a myth of the Khoi San people of southern Africa, as it portrays a girl throwing evening fire embers into the night sky, where they remained as the Milky Way.

  8. Mars in their eyes - a cartoon exhibition

    Science.gov (United States)

    Pillinger, Pi.

    Recently a collection of 120 cartoons which tell the story of Mars exploration and scientific discovery, past, present and future, was held in London. We discuss the aims of the exhibition, to what extent we believe the original aims were met and report on additional outreach opportunities resulting from the project. The overriding aim was to capitalise on the popular appeal of accessible art - most people admit to enjoying cartoons. This was strengthened by hanging the originals of cartoons which had, mostly, been published in newspapers and magazines in a wide selection of countries. The provenances served to indicate the attraction of Mars to a wide public. We were fortunate to work with the Cartoon Art Trust of the UK who was in the process of relocating to new premises and opening as The Cartoon Museum, in the tourist area of Bloomsbury, central London, very close to the British Museum. "Mars in their Eyes" ran for 10 weeks during April to July 2006; immediately following which a selection of the cartoons was displayed at the week-long Royal Society Summer Exhibition. We explore the differences between the two exhibitions and comment on the various audience responses. We use this comparison to discuss whether a project which is primarily art can be extended to explain science. Does the coupling merely result in dumbing-down of both cultures or is there a true synergy? The experience has led us to coin the phrase "extreme outreach". Projects which are as ambitious as "Mars in their Eyes", without the security of a safe, captive audience, for example at a Science Centre, must be judged by different criteria. Indeed if the project does not meet comparable targets like large visitor numbers, then the honest evaluation of such details can only inform future activities and must not be reflected in the future funding of only "safe" outreach activities.

  9. Art Therapy Exhibitions: Exploitation or Advocacy?

    Science.gov (United States)

    Davis, Terri

    2017-01-01

    Promoting awareness of human trafficking by sharing trauma survivors' art and summaries of their life stories suggests ethical complexities that have been typically neglected by bioethicists. Although these survivors voluntarily share the objects they created during art therapy sessions, they are still at risk of harm, including further exploitation, due to their vulnerability, high rates of victim sensitivity, and the mental health consequences of their traumatic experiences. While some argue that the benefits of sublimation and art therapy for human trafficking survivors make sharing their art worth the risk, anti-trafficking organizations and supporters of such art exhibitions have responsibilities to be trauma informed. © 2017 American Medical Association. All Rights Reserved.

  10. Library exhibits and programs boost science education

    Science.gov (United States)

    Dusenbery, Paul B.; Curtis, Lisa

    2012-05-01

    Science museums let visitors explore and discover, but for many families there are barriers—such as cost or distance—that prevent them from visiting museums and experiencing hands-on science, technology, engineering, and mathematics (STEM) learning. Now educators are reaching underserved audiences by developing STEM exhibits and programs for public libraries. With more than 16,000 outlets in the United States, public libraries serve almost every community in the country. Nationwide, they receive about 1.5 billion visits per year, and they offer their services for free.

  11. New Media Display Technology and Exhibition Experience

    Directory of Open Access Journals (Sweden)

    Chen-Wo Kuo

    2016-01-01

    Full Text Available As the inheritor of Chinese civilization, the National Palace Museum (hereafter referred to as the NPM, houses a world-class collection of cultural art and artifacts. Since the NPM began promoting the National Digital Archives Project in 2002, its efforts have expanded to develop a digital museum and various e-learning programs. Extending the use of digital archives to its educational and cultural industrial endeavors, the NPM has maximized the value of its exhibitions, publications, and educational programs.  In 2013, the NPM integrated creative thinking and interdisciplinary technologies, such as floating projection, augmented reality, and other sensory interactive media, to recreate the historical circumstance of 19th century East Asian maritime cultures in “Rebuilding the Tong-an Ships—New Media Art Exhibition," which opened at Huashan 1914 Creative Park and later won the Gold Award at the 2014 Digital Education Innovation Competition. Through a thorough exploration of the factors contributing to the success of "Rebuilding the Tong-an Ships," this study has isolated the two main factors of the exhibition’s popularity, namely, the compactness of the metadata and the atmosphere created by the interactive display technology.

  12. Children's drawings exhibited in the Globe

    CERN Multimedia

    Elizabeth Roe

    2010-01-01

    "Draw Me A Physicist" has been a success. Members of the public visiting the exhibition in the Globe of Science and Innovation have praised the scientific and creative balance the children of neighbouring France and the Canton of Geneva have obtained through their visit to CERN.   The Draw Me a Physicist exhibition in the Globe For a six-month period 9 to 11-year olds from the Pays de Gex, Meyrin, Satigny and Vernier have been able to enjoy a balance between science and art, through drawing and defining their interpretations of a physicist. In May, eight pairs of drawings from each participating class were selected by the schools to be displayed on the second floor of the Globe. Since the images have been put up, the viewers have enjoyed the contrast between the "before" pictures of vibrant Albert Einsteins to the "after" pictures of casual people sitting in an office. The large room in the Globe has been transformed from a hollow shell int...

  13. CERN Inspires Art in Major New Exhibition

    CERN Multimedia

    2001-01-01

    Signatures of the Invisible, an exhibition inspired by CERN, opened at the Atlantis Gallery in London on Thursday, 1 March before going on a world tour. The fruit of a close collaboration between CERN and the London Institute, the exhibition brings together works from many leading European contemporary artists. White wooden boxes on a grey floor... the lids opened, unveiling brilliant white light from a bunch of optical fibres carefully stuck together in the shape of a square. Another holds a treasure of lead glass surrounded by enigmatic black mirrors. What's it all about? Signatures of the Invisible, that's what, a joint project organised by the London Institute, one of the world's largest college of art, and our Laboratory. Damien Foresy from the EST workshop putting finishing touches to the spinning tops of French artist Jérôme Basserode. Monica Sand's boxes are just one of the many works based around materials used in particle detection at CERN that was admired at the opening o...

  14. Exhibition Season: Annual Archaeological Exhibitions in London, 1880s-1930s

    Directory of Open Access Journals (Sweden)

    Amara Thornton

    2015-03-01

    Full Text Available Annual archaeological exhibitions were a visible symbol of archaeological research. Held mainly in London, the displays encapsulated a network of archaeologists, artists, architects and curators, and showcased the work of the first generations of trained archaeologists. The exhibition catalogues and published reviews of the displays provide a unique method for exploring the reception and sponsorship of archaeological work overseas and its promotion to a fascinated, well connected and well moneyed public. The exhibitions were a space in which conversation and networking were as important as educational enrichment. This paper analyses the social history of the “annual exhibition” in archaeology, highlighting the development and maintenance of the networks behind archaeological research, the geography of London as a way to examine influence in archaeology, and the utility of exhibitions for archaeological publicity during this period of exploration.

  15. Virtual auditorium concepts for exhibition halls

    Science.gov (United States)

    Evans, Jack; Himmel, Chad; Knight, Sarah

    2002-11-01

    Many communities lack good performance facilities for symphonic music, opera, dramatic and musical arts, but have basic convention, exhibition or assembly spaces. It should be possible to develop performance space environments within large multipurpose facilities that will accommodate production and presentation of dramatic arts. Concepts for moderate-cost, temporary enhancements that transform boxy spaces into more intimate, acoustically articulated venues will be presented. Acoustical criteria and design parameters will be discussed in the context of creating a virtual auditorium within the building envelope. Physical, economic, and logistical limitations affect implementation. Sound reinforcement system augmentation can supplement the room conversion. Acceptable control of reflection patterns, reverberation, and to some extent, ambient noise, may be achieved with an array of nonpermanent reflector and absorber elements. These elements can sculpture an enclosure to approach the shape and acoustic characteristics of an auditorium. Plan and section illustrations will be included.

  16. Exhibiting health and medicine as culture

    DEFF Research Database (Denmark)

    Bencard, Adam; Tybjerg, Karin; Whiteley, Louise;

    2017-01-01

    This paper discusses the potential role of medical museums in public engagement with health and medicine, based in the work of Medical Museion at the University of Copenhagen. Rather than asking if cultural venues such as museums can directly improve the wellbeing of their visitors, we instead...... focus on how museums should communicate about health and medicine. There is increasing emphasis on the need for health communication to recognize peoples’ multiple, lived cultures. We argue that we should also recognize that medical research and practice is itself a form of culture......, and as such is multiple and historically shifting. We suggest that museums are an ideal site for doing so, and can thereby contribute to public engagement with medicine that acknowledges multiplicity on both sides. The paper describes three examples of exhibitions at Medical Museion that attempt to display medicine...

  17. Ketogenic diet exhibits anti-inflammatory properties.

    Science.gov (United States)

    Dupuis, Nina; Curatolo, Niccolo; Benoist, Jean-François; Auvin, Stéphane

    2015-07-01

    The ketogenic diet (KD) is an established treatment for refractory epilepsy, including some inflammation-induced epileptic encephalopathies. In a lipopolysaccharide (LPS)-induced fever model in rats, we found that animals given the KD for 14 days showed less fever and lower proinflammatory cytokine levels than control animals. However, KD rats exhibited a decrease in circulating levels of arachidonic acid and long-chain n-3 polyunsaturated fatty acids (PUFAs), suggesting that the anti-inflammatory effect of KD was probably not due to an increase in anti-inflammatory n-3 PUFA derivatives. These properties might be of interest in some conditions such as fever-induced refractory epileptic encephalopathy in school-aged children.

  18. A Traveling Exhibit of Cassini Image Science

    Science.gov (United States)

    Burns, Joseph A.; Hedman, M. M.; Tiscareno, M. S.; Ebel, D.; Mac Low, M.; Lovett, L. E.; Burns, J. K.; Schaff, N.; Bilson, E. M.

    2007-10-01

    An exhibit of Cassini's images will open at NYC's American Museum of Natural History in March 2008 and then visit the Johnson Art Museum (Cornell) throughout fall 2008, including during next year's DPS. It is under consideration by several other venues in the States and overseas. The exhibit will feature 40-50 images, ranging from letter size to large posters, taken by remote-sensing instruments aboard Cassini and Huygens. Photos will be organized into a half-dozen thematic clusters (e.g., organized by celestial target or by physical process); a panel will introduce each grouping with individual images identified briefly. The Saturn system is a perfect vehicle to educate citizens about planetary science and origins. The images’ beauty should capture the public's attention, allowing us to then engage their curiosity about the relevant science. Among the Saturn system's broad suite of objects are Enceladus and Titan, two satellites of astrobiological interest; moreover, the rings display many processes active in other astrophysical disks. Several auxiliary ideas will be implemented. In Ithaca, we will project images at night against the museum's sand-colored exterior walls. A 10-12 minute musical composition has been commissioned from Roberto Sierra to open the show. We will encourage school children to participate in a human orrery circling the museum and will seek volunteers to participate in several Saturnalia. At Cornell we will involve the university and local communities, by taping their reactions to the images’ exquisite beauty as well as to their scientific content. Cassini will be the E/PO focus of next year's DPS meeting; those materials will be employed throughout the fall at New York schools and be available to travel with the show. We intend to work with NYC partners to offer teacher credits for associated weekend courses. We will produce classroom materials, including a DVD, for teacher use.

  19. Extract from Ceratonia siliqua Exhibits Depigmentation Properties.

    Science.gov (United States)

    Lall, Namrita; Kishore, Navneet; Momtaz, Saeideh; Hussein, Ahmed; Naidoo, Sanushka; Nqephe, Mabatho; Crampton, Bridget

    2015-11-01

    Skin hyper-pigmentation is a condition initiated by the overproduction of melanin existing in the melanocytes. Melanin pigment is responsible for the colour of skin in humans. It is formed through a series of oxidative reactions involving the amino acid tyrosine in the presence of the key enzyme tyrosinase. In continuation with our efforts to identify tyrosinase inhibitors from plants sources, the methanol extract from leaf, bark and fruit of Ceratonia siliqua were screened for tyrosinase inhibition and diphenolase activity. The bark extract exhibited significant inhibition on mushroom tyrosinase using L-tyrosine as a substrate and showed diphenolase activity. The extract further significantly lowered tyrosinase mRNA levels in B16-F10 mouse melanocytes. Bioassay-guided fractionation led to the isolation of six compounds. Compounds (-)-epicatechin-3-O-gallate, 1,2,3,6-tetra-O-galloyl-ß-D-glucose and gallocatechin-3-O-gallate showed tyrosinase inhibitions with the IC50 values of 27.52, 83.30 and 28.30 µg/mL, respectively. These compounds also exhibited L-DOPA activities with IC50 values of >200, 150 and 200 µg/mL, respectively. A clinical study was conducted using 20 volunteers in a patch testing trial for irritancy potential and skin depigmentation. The clinical results showed the sample to be non-irritant with irritancy potential of -34.21 and depigmentation trial showed an improvement in the even skin tone of UV induced pigmentation at 3% after 28 days of application.

  20. Exhibition of Stochastic Resonance in Vestibular Perception

    Science.gov (United States)

    Galvan-Garza, R. C.; Clark, T. K.; Merfeld, D. M.; Bloomberg, J. J.; Oman, C. M.; Mulavara, A. P.

    2016-01-01

    Astronauts experience sensorimotor changes during spaceflight, particularly during G-transitions. Post flight sensorimotor changes include spatial disorientation, along with postural and gait instability that may degrade operational capabilities of the astronauts and endanger the crew. A sensorimotor countermeasure that mitigates these effects would improve crewmember safety and decrease risk. The goal of this research is to investigate the potential use of stochastic vestibular stimulation (SVS) as a technology to improve sensorimotor function. We hypothesize that low levels of SVS will improve sensorimotor perception through the phenomenon of stochastic resonance (SR), when the response of a nonlinear system to a weak input signal is enhanced by the application of a particular nonzero level of noise. This study aims to advance the development of SVS as a potential countermeasure by 1) demonstrating the exhibition of stochastic resonance in vestibular perception, a vital component of sensorimotor function, 2) investigating the repeatability of SR exhibition, and 3) determining the relative contribution of the semicircular canals (SCC) and otolith (OTO) organs to vestibular perceptual SR. A constant current stimulator was used to deliver bilateral bipolar SVS via electrodes placed on each of the mastoid processes, as previously done. Vestibular perceptual motion recognition thresholds were measured using a 6-degree of freedom MOOG platform and a 150 trial 3-down/1-up staircase procedure. In the first test session, we measured vestibular perceptual thresholds in upright roll-tilt at 0.2 Hz (SCC+OTO) with SVS ranging from 0-700 µA. In a second test session a week later, we re-measured roll-tilt thresholds with 0, optimal (from test session 1), and 1500 µA SVS levels. A subset of these subjects, plus naive subjects, participated in two additional test sessions in which we measured thresholds in supine roll-rotation at 0.2 Hz (SCC) and upright y-translation at 1 Hz

  1. Virtual Exhibition and Fruition of Archaeological Finds

    Science.gov (United States)

    Manferdini, A. M.; Garagnani, S.

    2011-09-01

    During the last two decades, since digital technologies have become more sophisticated in acquiring real data and building faithful copies of them, their improvements have suggested interesting applications in the field of valorisation of Historical, Cultural and Artistic Heritage, with significant consequences in the share and widespread of knowledge. But although several technologies and methodologies for 3d digitization have recently been developed and improved, the lack of a standard procedure and the costs connected to their use still doesn't encourage the systematic digital acquisition of wide collections and heritage. The aim of this paper is to show the state of the art of a project whose aim is to provide a methodology and a procedure to create digital reproductions of artefacts for Institutions called to preserve, manage and enhance the fruition of archaeological finds inside museums or through digital exhibitions. Our project's aim is to find the most suitable procedure to digitally acquire archaeo logical artefacts that usually have small dimensions and have very complex and detailed surfaces. Within our methodology, particular attention has been paid to the use of widely shared and open-source visualization systems that enhance the involvement of the user by emphasizing three-dimensional characteristics of artefacts through virtual reality.

  2. Modern museum exhibition technology revolution for audience

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Today's digital revolution leads to the increasing mobile device usage, which has changed people's life and work. However, the traditional static display and graphic version is unable to meet the requirements of the modern audience, which makes museums face the challenge in the distribution of knowledge. Meanwhile, the information storm produced by big data emerged a variety of new media, such as social media, Natural User Interface, Augmented Reality, and electronic publishing. This dizzying array of tools offered opportunities for museums all over the world to become more vibrant and accessible. Museums around the world have been constant changed and improved its presentation, which provides a valuable experience for us. The new Shanghai Natural History Museum has also applied information technology on exhibition, education, research and collection. But the change does not mean a complete subversion. Because the museum audience are di- verse, such as born in a different era, have different learning habits, museums need to control the change magnitude of display technology to meet the requirements of different audience.

  3. Rotating pigment cells exhibit an intrinsic chirality.

    Science.gov (United States)

    Yamanaka, Hiroaki; Kondo, Shigeru

    2015-01-01

    In multicellular organisms, cell properties, such as shape, size and function are important in morphogenesis and physiological functions. Recently, 'cellular chirality' has attracted attention as a cellular property because it can cause asymmetry in the bodies of animals. In recent in vitro studies, the left-right bias of cellular migration and of autonomous arrangement of cells under some specific culture conditions were discovered. However, it is difficult to identify the molecular mechanism underlying their intrinsic chirality because the left-right bias observed to date is subtle or is manifested in the stable orientation of cells. Here, we report that zebrafish (Danio rerio) melanophores exhibit clear cellular chirality by unidirectional counterclockwise rotational movement under isolated conditions without any special settings. The chirality is intrinsic to melanophores because the direction of the cellular rotation was not affected by the type of extracellular matrix. We further found that the cellular rotation was generated as a counter action of the clockwise movement of actin cytoskeleton. It suggested that the mechanism that directs actin cytoskeleton in the clockwise direction is pivotal for determining cellular chirality.

  4. Waves in geomaterials exhibiting negative stiffness behaviour

    Science.gov (United States)

    Esin, Maxim; Dyskin, Arcady; Pasternak, Elena

    2016-04-01

    Negative stiffness denotes the type of material behaviour when the force applied to the body decreases the body's deformation increases. Some geomaterials, for instance, rocks, demonstrate behaviour of this type at certain loads: during the compression tests the loading curves exhibit descending branch (post-peak softening). One of the possible mechanisms of the negative stiffness appearance in geomaterials is rotation of non-spherical grains. It is important to emphasize that in this case the descending branch may be reversible given that the testing machine is stiff enough (in general case it means an importance of boundary conditions). Existence of geomaterials with a negative modulus associated with rotations may have significant importance. In particular, important is understanding of the wave propagation in such materials. We study the stability of geomaterials with negative stiffness inclusions and wave propagation in it using two approaches: Cosserat continuum and discrete mass-spring models. In both cases we consider the rotational degrees of freedom in addition to the conventional translational ones. We show that despite non positiveness of the energy the materials with negative stiffness elements can be stable if certain conditions are met. In the case of Cosserat continuum the Cosserat shear modulus (the modulus relating the non-symmetrical part of shear stress and internal rotations) is allowed to assume negative values as long as its value does not exceed the value of the standard (positive) shear modulus. In the case of discrete mass-spring systems (with translational and rotational springs) the concentration of negative stiffness springs and the absolute values of negative spring stiffness are limited. The critical concentration when the system loses stability and the amplitude of the oscillations tends to infinity is equal to 1/2 and 3/5 for two- and three-dimensional cases respectively.

  5. STONETECH 2007 BEIJING Held At International Exhibition Center

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ On March 4-7, the 14th China International Stone Processing Machinery,Equipment and Products Exhibition (STONETECH 2007 BEIJING) was held in all exhibition halls of Beijing International Exhibition Center.

  6. Thermally reduced graphenes exhibiting a close relationship to amorphous carbon

    Science.gov (United States)

    An Wong, Colin Hong; Ambrosi, Adriano; Pumera, Martin

    2012-07-01

    Graphene is an important material for sensing and energy storage applications. Since the vast majority of sensing and energy storage chemical and electrochemical systems require bulk quantities of graphene, thermally reduced graphene oxide (TRGO) is commonly employed instead of pristine graphene. The sp2 planar structure of TRGO is heavily damaged, consisting of a very short sp2 crystallite size of nanometre length and with areas of sp3 hybridized carbon. Such a structure of TRGO is reminiscent of the key characteristic of the structure of amorphous carbon, which is defined as a material without long-range crystalline order consisting of both sp2 and sp3 hybridized carbons. Herein, we describe the characterization of TRGO, its parent graphite material and carbon black (a form of amorphous carbon) via transmission electron microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and cyclic voltammetry experiments. We used the data obtained as well as consideration of practical factors to perform a comparative assessment of the relative electrochemical performances of TRGO against amorphous carbon. We found out that TRGO and amorphous carbon exhibit almost identical characteristics in terms of density of defects in the sp2 lattice and a similar crystallite size as determined by Raman spectroscopy. These two materials also exhibit similar amounts of oxygen containing groups as determined by XPS and nearly indistinguishable cyclic voltammetric response providing almost identical heterogeneous electron transfer constants. This leads us to conclude that for some sensing and energy storage electrochemical applications, the use of amorphous carbon might be a much more economical solution than the one requiring digestion of highly crystalline graphite with strong oxidants to graphite oxide and then thermally exfoliating it to thermally reduced graphene oxide.

  7. An investigation of manganites exhibiting colossal magnetoresistance

    CERN Document Server

    Coldea, A I

    2001-01-01

    charge-ordered regions with possible phase separation. Magnetic field-induced transitions are reported and the effect of granularity on the magnetoresistance is studied. Effects of magnetic dilution with non-magnetic Ga and Rh ions on perovskite manganites, (La/Nd) sub 2 sub - sub x Sr sub x Mn(Ga/Rh)O sub 6 , are presented in Chapter 4. The random distribution of magnetic ions on the manganese network affects both the magnetic and electrical properties. As a function of hole doping x, La sub 2 sub - sub x Sr sub x MnGaO sub 6 compounds are ferromagnetic at low doping (x 0.3) become magnetically disordered due to the frustration induced by competing ferromagnetic and antiferromagnetic interactions. The Rh dilution helps stabilize the ferromagnetic phase in La sub 1 sub . sub 5 Sr sub 0 sub . sub 5 MnRhO sub 6. All compounds are insulating due to the charge localization induced by the random potential created by the local structural and magnetic disorder. The observed magnetoresistance is discussed either in ...

  8. Development of Exhibit on Arctic Climate Change Called The Arctic: A Friend Acting Strangely Exhibition

    Energy Technology Data Exchange (ETDEWEB)

    Stauffer, Barbara W.

    2006-04-01

    The exhibition, The Arctic: A Friend Acting Strangely, was developed at the Smithsonian Institution’s National Museum of Natural History (NMNH) as a part of the museum’s Forces of Change exhibit series on global change. It opened to the public in Spring 2006, in conjunction with another Forces of Change exhibit on the Earth’s atmosphere called Change Is in the Air. The exhibit was a 2000 square-foot presentation that explored the forces and consequences of the changing Arctic as documented by scientists and native residents alike. Native peoples of the Arctic have always lived with year-to-year fluctuations in weather and ice conditions. In recent decades, they have witnessed that the climate has become unpredictable, the land and sea unfamiliar. An elder in Arctic Canada recently described the weather as uggianaqtuq —an Inuit word that can suggest strange, unexpected behavior, sometimes described as that of “a friend acting strangely.” Scientists too have been documenting dramatic changes in the Arctic. Air temperatures have warmed over most—though not all—of the Arctic since the 1950s; Arctic precipitation may have increased by as much as 8%; seasonal melting of the Greenland Ice Sheet has increased on average by 16% since 1979; polar-orbiting satellites have measured a 15¬–20% decline in sea ice extent since the 1970s; aircraft reconnaissance and ship observations show a steady decrease in sea ice since the 1950s. In response to this warming, plant distributions have begun to shift and animals are changing their migration routes. Some of these changes may have beneficial effects while others may bring hardship or have costly implications. And, many scientists consider arctic change to be a ‘bell-weather’ for large-scale changes in other regions of the world. The exhibition included text, photos artifacts, hands-on interactives and other exhibitry that illustrated the changes being documented by indigenous people and scientists alike.

  9. Creating Virtual Exhibitions for Educational and Cultural Development

    Directory of Open Access Journals (Sweden)

    Gabriela DUMITRESCU

    2014-01-01

    Full Text Available The paper presents different tools and mechanisms to implement a virtual exhibition in different cultural areas, such as museums and libraries. Quality characteristics of virtual exhibitions are identified and described. The possibility to create native mobile applications for virtual exhibitions presentation is analyzed. The functional flow of creating a virtual exhibition is presented and discussed. The Seals - History Treasure exhibition is presented and significant historical documents are revealed.

  10. Exhibiting eugenics: response and resistance to a hidden history.

    Science.gov (United States)

    Brave, Ralph; Sylva, Kathryn

    2007-01-01

    Human Plants, Human Harvest: The Hidden History of California Eugenics is the first-ever exhibition on the history of eugenics in California. The disappearance of this history for half a century, and the consequent absence of a "collective menory", were the primary factors determining the exhibit's sttrcture and content. Responses to the exhibit confirmed that most visitors "never knew" about this history. The exhibit is described in some detail, with selected imagery from the exhibit reproduced. After the initial exhibition, responses of other museums and foundation officials revealed a continuing resistance to this history being publicly displayed, though the sources of resistance varied.

  11. Flexible flapping wings can exhibit quasi-periodic motion!

    Science.gov (United States)

    Bose, Chandan; Sarkar, Sunetra

    2016-10-01

    The dynamics of a flexible flapping wing is investigated by modelling it as a coupled nonlinear fluid-structure interaction (FSI) system in the low Reynolds number flow regime in accordance to the flight of flapping wing micro air vehicles (MAVs). A bifurcation analysis, by varying the free-stream wind velocity (U ∞) as the control parameter, revealed the presence of a new dynamics in the form of a quasi-periodic attractor in the flapping wing motion. The structural and aerodynamic nonlinearities present in the system cause a supercritical Hopf bifurcation, where stable limit cycle oscillation emerges from fixed point response beyond a critical value of the free-stream velocity. Further increasing the control parameter, another bifurcation named Neimark-Sacker bifurcation takes place and as a result, the flapping wing exhibits quasi-periodic motion. The presence of Neimark-Sacker bifurcation in the flapping flow-field dynamics is an interesting find and the present work focuses on it's associated dynamical behaviour. Various dynamical system tools like frequency spectra, phase space, Poincaré section, first return map have been implemented successfully to confirm the presence of quasi-periodicity.

  12. Designing museum exhibits that facilitate visitor reflection and discussion

    DEFF Research Database (Denmark)

    Skydsgaard, Morten Arnika; Andersen, Hanne Møller; King, Heather

    2016-01-01

    personal reflection but also prompted discussion. Participation, defined as including both physical interaction with exhibits, and dialogic interaction between visitors, facilitated the sharing of ideas and feelings between visitors. Exhibits with elements of curiosity and challenge were found to attract...

  13. Annual Report On China's Exhibition Industry 2009 (III)

    Institute of Scientific and Technical Information of China (English)

    China Council for the Promotion of International T

    2010-01-01

    @@ To better understand China's exhibition industry's development trend, and its policy regulation features, and industrial market characteristics, China Council for the Promotion of International Trade (CCPIT) organizes experts and scholars of the exhibition industry to compile and publish Annual Report on China's Exhibition Industry in both Chinese and English every year since 2004. After years of efforts, the Report has become a significant window for domestic and overseas insiders to know about Chinas exhibition industry.

  14. Exhibition of Design, Development and Manufacturing of Scalp Cooling Cap

    OpenAIRE

    2016-01-01

    Exhibition Narrative:\\ud University of Huddersfield and Paxman Coolers Limited showcased the output of a collaborative project that resulted in an innovative scalp-cooling cap at Arab Health 2016 Exhibition Dubai, UEA. In collaboration with Medilink Yorkshire & Humber at the Stand No: Z1G57. The Arab Health 2016 exhibition showcased more than 4,000 companies exhibiting their latest innovations to more than 130,000 healthcare professionals attending from 163 countries.

  15. A Phenomenological Investigation of Science Center Exhibition Developers' Expertise Development

    Science.gov (United States)

    Young, Denise L.

    2012-01-01

    The purpose of this study was to examine the exhibition developer role in the context of United States (U.S.) science centers, and more specifically, to investigate the way science center exhibition developers build their professional expertise. This research investigated how successfully practicing exhibition developers described their current…

  16. Ms.Brown is introducing their exhibition to Miss Jiang.

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Miss Jiang:I want to know more about the International HouseholdUtensil Exhibition.Ms.Brown:It is an exhibition with a 32-year history,catering to clientsfrom South Africa and Mexico.Over the past 32 years,the exhibition hasbeen well known for its high efficiency in signing contracts.

  17. Online Cultural Heritage Exhibitions: A Survey of Strategic Issues

    Science.gov (United States)

    Liew, Chern Li

    2006-01-01

    Purpose: This paper seeks to report findings from a study that looked at a range of strategic issues faced in the development, management and maintenance of online cultural heritage exhibitions. The study examined exhibitions from different types of cultural agencies and asked questions about whether, for instance, the exhibitions are part of the…

  18. 76 FR 68808 - Culturally Significant Objects Imported for Exhibition

    Science.gov (United States)

    2011-11-07

    ... Exhibition Determinations: ``Transition to Christianity: Art of Late Antiquity, 3rd-7th Century AD'' SUMMARY... objects to be included in the exhibition ``Transition to Christianity: Art of Late Antiquity, 3rd-7th Century AD,'' imported from abroad for temporary exhibition within the United States, are of...

  19. Weight lifting can facilitate appreciative comprehension for museum exhibits

    Directory of Open Access Journals (Sweden)

    Yuki eYamada

    2014-04-01

    Full Text Available Appreciation of exhibits in a museum can be equated to a virtual experience of lives in the contexts originally surrounding the exhibits. Here we focus on the importance of weight information, and hence tested whether experiencing a weight during museum exhibit appreciation affects the beholders’ satisfaction and recognition memory for the exhibits. An experiment was performed at a museum exhibiting skeletal preparations of animals. We used nine preparations and prepared four weight stimuli as weight cues in accordance with the actual weight of four of the preparations: Remaining five preparations was displayed without weight stimuli. In the cued condition, participants were asked to lift up the weight stimuli during their observation of the four exhibits. In the uncued condition, participants observed the exhibits without touching the weight stimuli. After observation of the exhibits, the participants responded to a questionnaire that measured their impressions of the exhibits and the museum, and performed a recognition test on the exhibits. Results showed that memory performance was better and viewing duration was longer with weight lifting instruction than without instruction. A factor analysis on the questionnaires revealed four factors (likeability, contentment, value, and quality. A path analysis showed indirect effects of viewing duration on memory performance and willingness-to-pay for the museum appreciation through the impression factors. Our findings provide insight into a new interactive exhibition that enables long appreciation producing positive effects on visitors’ impression, memory, and value estimation for exhibits.

  20. 45 CFR 1160.5 - Eligibility for domestic exhibitions.

    Science.gov (United States)

    2010-10-01

    ... AND ARTIFACTS INDEMNITY ACT § 1160.5 Eligibility for domestic exhibitions. An indemnity agreement for...-owned objects; (B) Exhibitions outside of the United States of domestic-owned objects; or (C) Exhibitions in the United States of both foreign- and domestic-owned objects, with the foreign-owned...

  1. Annual Report On China's Exhibition Industry 2009(II)

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ Section II Features of China's Exhibition Market To better reflect the features of China's exhibition market,based on the research results from 2005 t0 2008,the research team in 2009 continued to make a thorough survey of the exhibition market in Beijing,Shanghai and Guangzhou.

  2. Digital Natives: Creating Emergent Exhibitions through Digital Technologies

    DEFF Research Database (Denmark)

    Smith, Rachel Charlotte; Iversen, Ole Sejer; Dindler, Christian

    2011-01-01

    Digital Technology can support the creation of dialogical spaces in the museum, both playful and reflective, that allow audiences to engage in the ongoing construction and reproduction of cultural heritage creating novel connections between self and others and between past, present and future....... In this way, digital technology can contribute to the creation of emergent exhibitions in which the exhibition is created in dialogue between audiences and the museum. We present experiences from a current research project, the Digital Natives exhibition, in which digital technology was designed...... as an integral part of the exhibition to encourage dialogue between audiences and the exhibition materials and thereby investigate how the exhibition emerge as a result of this dialogic co-construction inside the exhibition space. In short, the opportunities offered by digital technologies prompts us to consider...

  3. Study the Effect of Sources of Manufacturing Companies on the Achievement of the Objectives of the Trade Exhibition: Case Study at the International Exhibition of Bushehr City

    Directory of Open Access Journals (Sweden)

    Majid Esmaeilpour

    2016-01-01

    Full Text Available Background: With increasing competition and reducing the possibility of exposure to commodities, the possibility of participating in trade exhibition is important hundredfold. Exhibiting a great opportunity for companies provide the goods. The exhibition will present a pre-determined targets and long-term planning to achieve these goals, the recognition of its resources in setting goals as a fundamental principle of the company, is participating in the exhibition. Objectives: The purpose of this study was to assess the importance sources of participating in trade exhibition and the impact that it will have sources of to achieve the objectives of the exhibition. Methodology: The study in term of purpose is applied and in term of data collection is descriptive - and the correlation. The research includes companies participating in international exhibition Bushehr over 180 companies. This study used a sample of 120 companies was Morgan. Data derived from the survey questionnaire. Validity through the content validity and reliability through Cronbach's alpha was approved. Data Analysis is a method of structural equation modeling. Results and findings: The results obtained suggest that the booth personnel sources of, sources of exhibition have a significant impact on sales targets and management capabilities. The booth personnel sources of and the ability to communicate with customers also have a significant impact on sales purposes. The findings of this study it can be concluded that except for the purposes of sale and non-sale capabilities partnership that does not, improvement of existing resources and capabilities of each model achieves sales targets and other participants will sell.

  4. Murine and human CFTR exhibit different sensitivities to CFTR potentiators.

    Science.gov (United States)

    Cui, Guiying; McCarty, Nael A

    2015-10-01

    Development of therapeutic molecules with clinical efficacy as modulators of defective CFTR includes efforts to identify potentiators that can overcome or repair the gating defect in mutant CFTR channels. This has taken a great leap forward with the identification of the potentiator VX-770, now available to patients as "Kalydeco." Other small molecules with different chemical structure also are capable of potentiating the activity of either wild-type or mutant CFTR, suggesting that there are features of the protein that may be targeted to achieve stimulation of channel activity by structurally diverse compounds. However, neither the mechanisms by which these compounds potentiate mutant CFTR nor the site(s) where these compounds bind have been identified. This knowledge gap partly reflects the lack of appropriate experimental models to provide clues toward the identification of binding sites. Here, we have compared the channel behavior and response to novel and known potentiators of human CFTR (hCFTR) and murine (mCFTR) expressed in Xenopus oocytes. Both hCFTR and mCFTR were blocked by GlyH-101 from the extracellular side, but mCFTR activity was increased with GlyH-101 applied directly to the cytoplasmic side. Similarly, glibenclamide only exhibited a blocking effect on hCFTR but both blocked and potentiated mCFTR in excised membrane patches and in intact oocytes. The clinically used CFTR potentiator VX-770 transiently increased hCFTR by ∼13% but potentiated mCFTR significantly more strongly. Our results suggest that mCFTR pharmacological sensitivities differ from hCFTR, which will provide a useful tool for identifying the binding sites and mechanism for these potentiators.

  5. Hydrocarbon-stapled lipopeptides exhibit selective antimicrobial activity.

    Science.gov (United States)

    Jenner, Zachary B; Crittenden, Christopher M; Gonzalez, Martín; Brodbelt, Jennifer S; Bruns, Kerry A

    2017-01-10

    Antimicrobial peptides (AMPs) occur widely in nature and have been studied for their therapeutic potential. AMPs are of interest due to the large number of possible chemical structural combinations using natural and unnatural amino acids, with varying effects on their biological activities. Using physicochemical properties from known naturally occurring amphipathic cationic AMPs, several hydrocarbon-stapled lipopeptides (HSLPs) were designed, synthesized, and tested for antimicrobial properties. Peptides were chemically modified by N-terminal acylation, C-terminal amidation, and some were hydrocarbon stapled by intramolecular olefin metathesis. The effects of peptide length, amphipathic character, and stapling on antimicrobial activity were tested against Escherichia coli, three species of Gram-positive bacteria (Staphylococcus aureus, Bacillus megaterium, and Enterococcus faecalis), and two strains of Candida albicans. Peptides were shown to disrupt liposomes of different phospholipid composition, as measured by leakage of a fluorescent compound from vesicles. Peptides with (S)-2-(4'-pentenyl)-alanine substituted for L-alanine in a reference peptide showed a marked increase in antimicrobial activity, hemolysis, and membrane disruption. Stapled peptides exhibited slightly higher antimicrobial potency; those with greatest hydrophobic character showed the greatest hemolysis and liposome leakage, but lower antimicrobial activity. The results support a model of HSLPs as membrane-disruptive AMPs with potent antimicrobial activity and relatively low hemolytic potential at biologically active peptide concentrations. This article is protected by copyright. All rights reserved.

  6. CERN exhibition attracts over 100,000 visitors in Belgrade

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    “This must be an 'all-time record',” says Ray Lewis, CERN travelling exhibition manager. “In all my time with the various permanent and travelling exhibitions that have taken place locally and within our Member States I have never experienced such figures.”   Zarko Obradovic (left), Serbian Minister of Education, Science and Technology, and Rolf Heuer (right), CERN Director-General, at the CERN travelling exhibition in Belgrade. Indeed, in approximately 20 days of exhibition time about 120,000 people, mainly school visiters and the general public, visited the 100 m2 CERN mini-exhibition. It was set up in the centre of Belgrade in October, in association with the meeting of the Restricted European Committee for Future Accelerators (RECFA). After attending the RECFA meeting, CERN's Director-General Rofl Heuer opened the CERN exhibition on the evening of 19 October. Lectures about CERN were held every afternoon, and two public de...

  7. The Exhibition Performance Appraisal Index System Based on Stakeholder Theory

    Institute of Scientific and Technical Information of China (English)

    YAN Shu-min; HAO Qi-hui

    2009-01-01

    Exhibition performance should be evaluated from different perspectives of stakeholders. The benefits of each stakeholder can not be satisfied when evaluating the exhibition performance from a single perspective or. only evaluating the economic performance of the exhibition. In this paper, the stakeholders are defined on the basis of questionnaire investigation and classified by mathematical statistical method. According to the requirements of the stakeholders, the exhibition performance appraisal indicators are extracted and, simplified by factor analysis, which leads to the formation of a set of performance appraisal index system. It is an instructive attempt to work out the exhibition performance appraisal model from the perspective of stakeholders, which may provide theoretical foundation and practice instruction for exhibition performance appraisal in our country.

  8. A content-oriented model for science exhibit engineering

    DEFF Research Database (Denmark)

    Achiam, Marianne

    2013-01-01

    : as a means to operationalize the link between exhibit features and visitor activities; and as a template to transform scientists’ practices in the research context into visitors’ activities in the exhibit context. The resulting model of science exhibit engineering is presented and exemplified, and its...... in prompting visitors to carry out intended actions, exhibits do not necessarily promote the intended interpretations of these actions among visitors. Here, the notion of praxeology from didactics research is suggested as a model to remedy this shortcoming. The suggested role of praxeology is twofold......Recently, science museums have begun to review their educational purposes and redesign their pedagogies. At the most basic level, this entails accounting for the performance of individual exhibits, and indeed, in some cases, research indicates shortcomings in exhibit design: While often successful...

  9. 22 CFR Exhibit B to Part 204 - Assignment

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Assignment B Exhibit B to Part 204 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HOUSING GUARANTY STANDARD TERMS AND CONDITIONS Pt. 204, Exh. B Exhibit B to Part 204—Assignment The undersigned, being the registered owner of a Note in the...

  10. FOTON Motor Crowns 4th China Auto International Circuit Exhibition

    Institute of Scientific and Technical Information of China (English)

    Wu; Yan

    2005-01-01

      In order to provide more opportuni ties for the high-developing Chinese auto industry including autos and motos to do export, and to enlarge the international influence of Chinese cars,the 4th China Auto International Circuit Exhibition will be held in Syria. The exhibition has been held for three times.……

  11. FOTON Motor Crowns 4th China Auto International Circuit Exhibition

    Institute of Scientific and Technical Information of China (English)

    Wu Yan

    2005-01-01

    @@ In order to provide more opportuni ties for the high-developing Chinese auto industry including autos and motos to do export, and to enlarge the international influence of Chinese cars,the 4th China Auto International Circuit Exhibition will be held in Syria. The exhibition has been held for three times.

  12. EXHIBITION TAKES GREAT EMPEROR’S LIFE TO FRANCE

    Institute of Scientific and Technical Information of China (English)

    SuSan

    2003-01-01

    “Court Life of Great Emperor Kang Xi a grand-scale exhibition organized by the Forbidden City Museum, will be held in Versailles, Paris in October 2003. The exhibition will be a highlight of the "China Cultural Year in France”.

  13. Perspectives on ... Multiculturalism and Library Exhibits: Sites of Contested Representation

    Science.gov (United States)

    Reece, Gwendolyn J.

    2005-01-01

    This article analyzes a multicultural library exhibit presenting the Palestinian/Israeli conflict as a site of contested representation. Qualitative methodology is used to interrogate the exhibit and its audience reception. Drawing on insights from critical pedagogy, implications for libraries arising from this case study are given and suggestions…

  14. CERN Industrials Exhibitions - Over 30 Years of Tradition

    CERN Multimedia

    2001-01-01

    Industrial exhibitions have been part of the CERN landscape for 33 years. At least once each year several companies from the same country come to CERN to present their products and services. Now, a new scheme of one-day visits is giving potential exhibitors at CERN a lighter option. The United Kingdom inaugurated the Industrial Exhibitions in 1968, and it wasn't till 1971 that other countries staged exhibitions at CERN. This photo was taken in 1969, at the second British exhibition, where 16 companies were present. Four years after joining CERN, Poland inaugurated its first exhibition at CERN in 1995 in the presence of the former Director-General Chris Llewellyn-Smith. Almost all the Member States have held industrial exhibitions at the Organization. May '68 wasn't only revolutionary in Paris. For the very first time, an industrial exhibition took place at CERN. Great Britain was first to come with eight companies and remains until this day the most devoted country to the programme with 17 exhibitions and ...

  15. The Signatures of the Invisible exhibition in Geneva

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    The artist Paola Pivi with her work at the Signatures of the Invisible exhibition in Geneva during February 2002. This piece with needles suspended on nylon thread 'detects' people as they approach. The exhibition was for art inspired by research carried out at CERN.

  16. Online Cultural Heritage Exhibitions: A Survey of Information Retrieval Features

    Science.gov (United States)

    Liew, Chern Li

    2005-01-01

    Purpose: What kinds of online cultural heritage exhibitions are now available on the internet? How far have these cultural heritage institutions voyaged in terms of harnessing the power of information and communication technology and the interactivity of multimedia systems to exhibit cultural heritage resources? This study aims to highlight the…

  17. 78 FR 7849 - Culturally Significant Objects Imported for Exhibition

    Science.gov (United States)

    2013-02-04

    ... Opulence: British Art at the Dawn of the Twentieth Century,'' imported from abroad for temporary exhibition... Culturally Significant Objects Imported for Exhibition Determinations: ``Edwardian Opulence: British Art at the Dawn of the Twentieth Century'' SUMMARY: Notice is hereby given of the following...

  18. Outreach to Science Faculty and Students through Research Exhibitions

    Science.gov (United States)

    Chan, Tina; Hebblethwaite, Chris

    2014-01-01

    Penfield Library at the State University of New York at Oswego (SUNY Oswego) has a gallery exhibit space near the front entrance that is used to showcase student-faculty research and art class projects. This article features the library's outreach efforts to science faculty and students through research exhibitions. The library held an exhibition…

  19. Using Museum Exhibits: An Innovation in Experiential Learning

    Science.gov (United States)

    Das, Satarupa

    2015-01-01

    Museum exhibits can be a tool in experiential learning. While instructors have documented various methods of experiential learning, they have not sufficiently explored such learning from museum exhibits. Museum researchers, however, have long found a satisfying cognitive component to museum visits. This paper narrates the author's design to…

  20. Healthy Development of Exhibition Industry——CCPIT's Deep Concern

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ 2008: National Exhibition Industrial Association should be established as soon as possible Exhibition industry, often renowned as the locomotive of the tertiary industry, is highly profitable smokeless industry (the profit rate is up to 20%-25% in the developed countries).

  1. Using Museum Exhibits: An Innovation in Experiential Learning

    Science.gov (United States)

    Das, Satarupa

    2015-01-01

    Museum exhibits can be a tool in experiential learning. While instructors have documented various methods of experiential learning, they have not sufficiently explored such learning from museum exhibits. Museum researchers, however, have long found a satisfying cognitive component to museum visits. This paper narrates the author's design to…

  2. 45 CFR 1160.4 - Eligibility for international exhibitions.

    Science.gov (United States)

    2010-10-01

    ... AND ARTIFACTS INDEMNITY ACT § 1160.4 Eligibility for international exhibitions. An indemnity agreement...- and domestic-owned objects in an international exhibition. The foreign-owned objects are eligible for indemnity coverage under paragraph (a) of this section, and the domestic-owned objects may be eligible...

  3. How Children View Their World: Three Exhibitions of Children's Art.

    Science.gov (United States)

    Reed, Judith

    1979-01-01

    Describes three traveling art exhibitions assembled by the U.S. Committee for UNICEF from its collection to mark the International Year of the Child. Exhibitions of children's paintings, drawings, and prints from virtually every nation in the world will tour American cities through the spring of 1980. (RH)

  4. Exhibition at CERN's Globe of Science and Innovation

    CERN Multimedia

    Claudia Marcelloni

    2006-01-01

    Here we see pictures of displays at one of the exhibitions held at the Globe of Science and Innovation taken in September 2006. Located opposite the main CERN site, the Globe houses many public exhibitions throughout the year covering many topics from astronomy to particle physics.

  5. Sponsorship and exhibitions at Nordic science centres and museums

    DEFF Research Database (Denmark)

    Davidsson, Eva; Sørensen, Helene

    2010-01-01

    Science and technology centres (STC) and science museums tend increasingly to rely on external economic support in order to create new exhibitions. But in what ways may the economic situation affect what is presented in their exhibitions? This article aims to explore how staff members consider...

  6. Data Collection Methods for Evaluating Museum Programs and Exhibitions

    Science.gov (United States)

    Nelson, Amy Crack; Cohn, Sarah

    2015-01-01

    Museums often evaluate various aspects of their audiences' experiences, be it what they learn from a program or how they react to an exhibition. Each museum program or exhibition has its own set of goals, which can drive what an evaluator studies and how an evaluation evolves. When designing an evaluation, data collection methods are purposefully…

  7. CERN’s travelling exhibition goes to Austria

    CERN Document Server

    Mélissa Lanaro

    2011-01-01

    Since April 2009 CERN’s travelling exhibition has been touring through some of the Organization's Member States. After Italy and Denmark it has been on show since February at Austria’s Hartberg Ökopark, a very popular science museum situated some one hundred kilometres from Vienna. To coincide with the CERN exhibition, Austria’s scientific community has organised a series of events for the general public which have had marked success. The exhibition's next destination will be Portugal and preparations are already underway to ensure that it is another resounding success   The travelling exhibition was designed in collaboration with the University of Geneva, as part of the celebrations for its 450th anniversary, and has already notched up a good number of kilometres as it travels from country to country. “In 2010 the exhibition already had around 55,000 visitors,” explains Rolf Landua, who heads the Education Group. Since its inauguration ...

  8. Ants exhibit asymmetric hybridization in a mosaic hybrid zone.

    Science.gov (United States)

    Purcell, Jessica; Zahnd, Sacha; Athanasiades, Anouk; Türler, Rebecca; Chapuisat, Michel; Brelsford, Alan

    2016-10-01

    Research on hybridization between species provides unparalleled insights into the pre- and postzygotic isolating mechanisms that drive speciation. In social organisms, colony-level incompatibilities may provide additional reproductive barriers not present in solitary species, and hybrid zones offer an opportunity to identify these barriers. Here, we use genotyping-by-sequencing to sequence hundreds of markers in a hybrid zone between two socially polymorphic ant species, Formica selysi and Formica cinerea. We characterize the zone, determine the frequency of hybrid workers, infer whether hybrid queens or males are produced and investigate whether hybridization is influenced by colony social organization. We also compare cuticular hydrocarbon profiles and aggression levels between the two species. The hybrid zone exhibits a mosaic structure. The asymmetric distribution of hybrids skewed towards F. cinerea suggests a pattern of unidirectional nuclear gene flow from F. selysi into F. cinerea. The occurrence of backcrossed individuals indicates that hybrid queens and/or males are fertile, and the presence of the F. cinerea mitochondrial haplotype in 97% of hybrids shows that successful F1 hybrids will generally have F. cinerea mothers and F. selysi fathers. We found no evidence that social organization contributes to speciation, because hybrids occur in both single-queen and multiple-queen colonies. Strongly differentiated cuticular hydrocarbon profiles and heightened interspecific aggression further reveal that species recognition cues are both present and perceived. The discovery of fertile hybrids and asymmetrical gene flow is unusual in ants, and this hybrid zone will therefore provide an ideal system with which to investigate speciation in social insects.

  9. High- compared to low-arched athletes exhibit smaller knee abduction moments in walking and running.

    Science.gov (United States)

    Powell, Douglas W; Andrews, Samantha; Stickley, Cris; Williams, D S Blaise

    2016-12-01

    High- (HA) and low-arched athletes (LA) experience distinct injury patterns. These injuries are the result of the interaction of structure and biomechanics. A suggested mechanism of patellofemoral pain pertains to frontal plane knee moments which may be exaggerated in LA athletes. We hypothesize that LA athletes will exhibit greater peak knee abduction moments than high-arched athletes.

  10. Between Exoticism and Universalism: Educational Sections in Latin American Participation at International Exhibitions, 1860-1900

    Science.gov (United States)

    Dussel, Ines

    2011-01-01

    International exhibitions provide a good arena in which to study the circulation and transfer of educational ideas and practices in the second half of the nineteenth century. Structured around themes of industry, progress, and civilisation, and defined as ephemeral museums of the new world of commodities for the consumption of the masses, they…

  11. Asian Martial Art Exhibitions at the Swiss Castle of Morges

    Directory of Open Access Journals (Sweden)

    Nicolae Gothard Bialokur

    2012-07-01

    Full Text Available This article reports on two unique cultural exhibitions (2005 and 2007 held in Morges, Switzerland. The main theme for these exhibitions was Asian martial arts with a focus on those from Japan, including presentations by notable masters in aikido, karate, judo, kyudo, iaido, kenjutsu, jodo, juttejutsu, kusarigamajutsu, naginatajutsu, tameshigiri, and kendo. On exhibit were artifacts from Morges Castle museum collections as well as numerous ancient objects borrowed specifically for these exhibitions from other Swiss museums and private collections. There was also a lecture on Japanese sword collecting and care, and presentations of Japanese dance, flower arranging (ikebana, the art of tea (châ no yu, châdo, paper folding (origami, traditional kimono dress, and detailed demonstrations on the manufacture of bladed weapons. Text and photography were arranged to record these events for this article, showing how excellent organization and cooperation can introduce high-quality martial traditions to the public.

  12. Dutch hi-tech companies exhibit at CERN

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    Twenty-seven Dutch companies will present the state of the art of their technological developments at the industrial exhibition Holland @ CERN from 8 to 11 November. The exhibition is designed to help strengthen the ties between fundamental science and Dutch industry.   The exhibition, supported by the Dutch Ministry of Economic Affairs and organised by the Netherlands National Institute for Subatomic Physics (Nikhef), in cooperation with the Foundation for Fundamental Research on Matter (FOM), the FOM Institute for Plasma Physics Rijnhuizen, and Dutch Scientific, an association of manufacturers of scientific equipment, will be held in the Main Building from 8 to11 November. “The last Holland @ CERN exhibition took place fifteen years ago”, says Robert Klöpping from Nikhef, Dutch Industrial Liaison Officer for CERN and Purchasing Advisor for Grenoble ESRF. “This kind of event is very important for Dutch industry as it allows us to show what Dutch companies c...

  13. Knowledge generation in technology-enhanced health exhibitions

    DEFF Research Database (Denmark)

    Magnussen, Rikke; Kharlamov, Nikita; Zachariasssen, Maria;

    2016-01-01

    age 6–12. Health promotion technologies are defined here, as technologies designed specifically for the purpose of health promotion, be they educational or focused on physical activities. The study was conducted in late 2015 and comprised eight families with children in 2nd-6th grade visiting...... in health promotion exhibitions designed to include direct physical interaction. The current study is part of the larger PULSE project, which aims to develop innovative health promotion activities that include a science museum exhibition as a key setting. The primary target group is families with children...... with the exhibition to understand how they had experienced the exhibition, what they saw as the thematic focus and if they thought they had gained new knowledge from the activities. Results from the project indicated that the participants gained knowledge linked to both health fitness topics and social aspects...

  14. Science, providence, and progress at the Great Exhibition.

    Science.gov (United States)

    Cantor, Geoffrey

    2012-09-01

    The Great Exhibition of 1851 is generally interpreted as a thoroughly secular event that celebrated progress in science, technology, and industry. In contrast to this perception, however, the exhibition was viewed by many contemporaries as a religious event of considerable importance. Although some religious commentators were highly critical of the exhibition and condemned the display of artifacts in the Crystal Palace as giving succor to materialism, others incorporated science and technology into their religious frameworks. Drawing on sermons, tracts, and the religious periodical press, this essay pays close attention to the ways in which science and technology were endowed with providentialist significance and particularly examines the notion of human progress used by a number of Christian writers, especially Congregationalists, who set scientific and technological progress within a teleological religious perspective. This discussion sheds fresh light not only on the Great Exhibition itself but also on the deployment of natural theology in mid-nineteenth-century Britain.

  15. "Britain at CERN" exhibition, from 14 to 17 November 2000

    CERN Multimedia

    Patrice Loïez

    2000-01-01

    H.E. Mr. Christopher Hulse, Ambassador of United Kingdom in Switzerland, CERN Director General Luciano Maiani, Sir David Wright, Chief Executive of British Trade International and Roger Cashmore, CERN Director of research visit the Britain at CERN exhibition

  16. 40 CFR 17.12 - Net worth exhibit.

    Science.gov (United States)

    2010-07-01

    ... JUSTICE ACT IN EPA ADMINISTRATIVE PROCEEDINGS Information Required From Applicants § 17.12 Net worth exhibit. (a) Each applicant except a qualified tax exempt organization or a qualified cooperative...

  17. 7 CFR 1.191 - Net worth exhibit.

    Science.gov (United States)

    2010-01-01

    ... Equal Access to Justice Act in Proceedings Before the Department Information Required from Applicants § 1.191 Net worth exhibit. (a) An applicant, except a qualified tax-exempt organization or...

  18. 45 CFR 13.11 - Net worth exhibits.

    Science.gov (United States)

    2010-10-01

    ... TO JUSTICE ACT IN AGENCY PROCEEDINGS Information Required from Applicants § 13.11 Net worth exhibits... requirement does not apply to a qualified tax-exempt organization or cooperative association. Nor does...

  19. Ballroom Music Spillover into a Beluga Whale Aquarium Exhibit

    Directory of Open Access Journals (Sweden)

    Peter M. Scheifele

    2012-01-01

    Full Text Available It is not uncommon for modern aquaria to be built with special entertainment areas. There are no known measurements of sound spillover from such entertainment areas into underwater animal exhibits. Entertainment organizations typically prefer to play music for events at 95 and 100 dBA in a ballroom at Georgia Aquarium. Concern over the potential effects of the music and noise on animals in adjacent exhibits inspired an initial project to monitor and compare sound levels in the adjacent underwater exhibits against the typical in-air sound levels of the ballroom. Measured underwater noise levels were compared to modeled levels based on finite element analysis and plane wave transmission loss calculations through the acrylic viewing window. Results were compared with the model to determine how, if at all, the ambient noise level in the Cold Water Quest exhibit changed as a result of music played in the ballroom.

  20. Development and Demand Analysis of Convention and Exhibition Industry Standardization

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This article points out the necessity and urgency of accelerating convention and exhibition industrial standardization on the basis of an analysis of the industry demands, developing tendencies, and existing problems during development.

  1. Successful 5th China International Diecasting Congress & Exhibition

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ The 5th China International Diecasting Congress & Exhibition organized by the Foundry Institution of Chinese Mechanical Engineering Society (FICMES) was successfully held in Shanghai, China on June 28to July 1, 2006.

  2. Implementing Mobile Virtual Exhibition to Increase Cultural Heritage Visibility

    National Research Council Canada - National Science Library

    Cristian Ciurea; Alin Zamfiroiu; Alin Grosu

    2014-01-01

      The paper presents an implementation of iOS mobile application designed as a virtual exhibition, which aims to increase the accessibility and visibility of physical objects that composite cultural heritage elements...

  3. Ballroom Music Spillover into a Beluga Whale Aquarium Exhibit

    OpenAIRE

    Scheifele, Peter M.; John Greer Clark; Kristine Sonstrom; Huikwan Kim; Gopu Potty; Miller, James H.; Eric Gaglione

    2012-01-01

    It is not uncommon for modern aquaria to be built with special entertainment areas. There are no known measurements of sound spillover from such entertainment areas into underwater animal exhibits. Entertainment organizations typically prefer to play music for events at 95 and 100 dBA in a ballroom at Georgia Aquarium. Concern over the potential effects of the music and noise on animals in adjacent exhibits inspired an initial project to monitor and compare sound levels in the adjacent underw...

  4. Foreign Investors Able to Establish Foreign- exclusively Exhibition Corporations

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Foreign Investors Able to Establish Foreign-exclusively Exhibition Corporations In Feb, Ministry of Commerce issued its 1st decree on temporary regulation for foreign-investing corporations; the regulation allows foreign investors to set up foreign-investing convention & exhibition corporations exclusively or through cooperation with other Chinese corporations, enterprises or organizations. With legal protection on their regulatory management and legal rights, these foreign-investing corporations are in the charge of Department of Foreign Investment Administration, Ministry of Commerce.

  5. The 1996 AAAI Mobile Robot Competition and Exhibition

    OpenAIRE

    Kortenkamp, David; Nourbakhsh, Illah; Hinkle, David

    1997-01-01

    The Fifth Annual AAAI Mobile Robot Competition and Exhibition was held in Portland, Oregon, in conjunction with the Thirteenth National Conference on Artificial Intelligence. The competition consisted of two events: (1) Office Navigation and (2) Clean Up the Tennis Court. The first event stressed navigation and planning. The second event stressed vision sensing and manipulation. In addition to the competition, there was a mobile robot exhibition in which teams demonstrated robot behaviors tha...

  6. Designing museum exhibits that facilitate visitor reflection and discussion

    DEFF Research Database (Denmark)

    Skydsgaard, Morten Arnika; Andersen, Hanne Møller; King, Heather

    2016-01-01

    personal reflection but also prompted discussion. Participation, defined as including both physical interaction with exhibits, and dialogic interaction between visitors, facilitated the sharing of ideas and feelings between visitors. Exhibits with elements of curiosity and challenge were found to attract...... pupils’ attention but also worked well with other design principles to engage the pupils in sustained reflection and discussion. While other contextual factors remain significant in determining visitor responses, this paper argues that the use of design principles can help create visitor experiences...

  7. [Is it allowed to have a public open exhibition of human plastinated specimens in Japan?].

    Science.gov (United States)

    Masuda, Y; Yohro, T

    1997-02-01

    This survey was conducted to know what inhibits the public open exhibitions of human anatomical specimens. Questionnaires were handed to 1,035 visitors to the public open exhibition of plastinated specimens at the University of Tokyo between March 30 and April 4, 1995. Five hundred and twenty-two responses were analyzed. The survey revealed following responses of medial and non-medical visitors. 1) Over 90 percent of the visitors welcomed to the public open exhibition of human anatomical specimens. 2) Visitors concerned about the aim of the exhibition and hoped explanations of exhibited specimens. They thought it is necessary to pay attention to the privacy of the cadavers and their families. 3) The most impressive specimens to the visitors were whole body silicone specimens and a series of slices of a whole body for both medical and non-medical visitors. 4) Medical visitors evaluated specimens high for medical education to understand three dimensional structures. On the contrary, non-medical visitors are astonished to encounter the whole body specimens not the dissected ones, and found the identity and human beings in the specimens. 5) Some anatomists strongly stand against the public open exhibitions of anatomical specimens because the plastinated specimens are quite different from ordinary hormaline fixed specimens and they expect that non-medical people must get upset about the specimens.

  8. A phenomenological investigation of science center exhibition developers' expertise development

    Science.gov (United States)

    Young, Denise L.

    The purpose of this study was to examine the exhibition developer role in the context of United States (U.S.) science centers, and more specifically, to investigate the way science center exhibition developers build their professional expertise. This research investigated how successfully practicing exhibition developers described their current practices, how they learned to be exhibition developers, and what factors were the most important to the developers in building their professional expertise. Qualitative data was gathered from 10 currently practicing exhibition developers from three science centers: the Exploratorium, San Francisco, California; the Field Museum, Chicago, Illinois; and the Science Museum of Minnesota, St. Paul, Minnesota. In-depth, semistructured interviews were used to collect the data. The study embraced aspects of the phenomenological tradition and sought to derive a holistic understanding of the position and how expertise was built for it. The data were methodically coded and organized into themes prior to analysis. The data analysis found that the position consisted of numerous and varied activities, but the developers' primary roles were advocating for the visitor, storytelling, and mediating information and ideas. They conducted these activities in the context of a team and relied on an established exhibition planning process to guide their work. Developers described a process of learning exhibition development that was experiential in nature. Learning through daily practice was key, though they also consulted with mentors and relied on visitor studies to gauge the effectiveness of their work. They were adept at integrating prior knowledge gained from many aspects of their lives into their practice. The developers described several internal factors that contributed to their expertise development including the desire to help others, a natural curiosity about the world, a commitment to learning, and the ability to accept critique. They

  9. Black Holes Traveling Exhibition: This Time, It's Personal.

    Science.gov (United States)

    Dussault, Mary E.; Braswell, E. L.; Sunbury, S.; Wasser, M.; Gould, R. R.

    2012-01-01

    How can you make a topic as abstract as black holes seem relevant to the life of the average museum visitor? In 2009, the Harvard-Smithsonian Center for Astrophysics developed a 2500 square foot interactive museum exhibition, "Black Holes: Space Warps & Time Twists,” with funding from the National Science Foundation and NASA. The exhibition has been visited by more than a quarter million museum-goers, and is about to open in its sixth venue at the Reuben H. Fleet Science Center in San Diego, California. We have found that encouraging visitors to adopt a custom black hole explorer's identity can help to make the science of black holes more accessible and meaningful. The Black Holes exhibition uses networked exhibit technology that serves to personalize the visitor experience, to support learning over time including beyond the gallery, and to provide a rich quantitative source of embedded evaluation data. Visitors entering the exhibition create their own bar-coded "Black Holes Explorer's Card” which they use throughout the exhibition to collect and record images, movies, their own predictions and conclusions, and other black hole artifacts. This digital database of personal discoveries grows as visitors navigate through the gallery, and an automated web-content authoring system creates a personalized online journal of their experience that they can access once they get home. We report here on new intriguing results gathered from data generated by 112,000 visitors across five different venues. For example, an initial review of the data reveals correlations between visitors’ black hole explorer identity choices and their engagement with the exhibition. We will also discuss correlations between learning gains and personalization.

  10. “Accelerating Science” exhibition zooms to Turkey

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    'Accelerating Science', CERN’s travelling science outreach exhibition, has just arrived at the Middle East Technical University (METU) in Ankara, Turkey for a four-month stay there. This is the first time it has moved outside the circle of the Member States. The Turkish venue will inaugurate some new exhibits that have recently been developed by CERN’s software developers.   “It’s been a very busy day,” says Bilge Demirkoz, an associate professor of physics at METU and a member of AMS-02, who had been overseeing the unloading of the lorries when we spoke to her. “As the University doesn’t have a specific exhibition space, the CERN exhibits are going to be housed in the covered tennis courts just behind the cultural and congress centre. It’s a beautiful venue, and there are plenty of parking spaces.” The University has sent invitations to the exhibition to high schools and to about 100 ...

  11. Knowledge Generation in Technology-Enhanced Health Exhibitions

    DEFF Research Database (Denmark)

    Magnussen, Rikke; Kharlamov, Nikita; Zachariasssen, Maria

    2016-01-01

    This paper presents results from eye-tracking studies of audience interaction and knowledge generation in the technology-enhanced health promotion exhibition PULSE at a science centre in Copenhagen, Denmark. The main purpose of the study was to understand what types of knowledge audiences build...... in health promotion exhibitions designed to include direct physical interaction. The current study is part of the larger PULSE project, which aims to develop innovative health promotion activities that include a science museum exhibition as a key setting. The primary target group is families with children...... age 6–12. Health promotion technologies are defined here, as technologies designed specifically for the purpose of health promotion, be they educational or focused on physical activities. The study was conducted in late 2015 and comprised eight families with children in 2nd-6th grade visiting...

  12. A Managerial Approach To A Controversial Exhibition: The Human Body

    Directory of Open Access Journals (Sweden)

    Viorica Aura Păuş

    2013-12-01

    Full Text Available This paper will analyse the reception of the Human Body exhibition of 2013 in Romania, from a managerial point of view. The research is based on the exhibition visitors’ book, to which a content analysis was applied. The main aim of the paper is to investigate how the ‘Grigore Antipa’ Museum (Romania constructed the cultural context in which the scientific arguments prevailed over the religious ones, turning the exhibition of plastinated human bodies into an accepted public event, with a strong emphasis on education and science (medicine. At the same time, ethical concerns and religious criticism were downplayed by maintaining the focus on the ‘education for health’ frame.

  13. Exhibition of Masayuki Miyata's Works of Art

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    To commemorate the 25th anniversary of the signing of the Sino-Japanese Peace and Friendship Treaty, the CPAFFC held the exhibition of Masayuki Miyata's works of art in the Painting Exhibition Hall of the Palace Museum from October 23 to 27, 2003. Miyata's 124 best works were selected for the exhibition, among which works on the subjects about China and those about Japan were half and half. They drew their materials mainly from Chinese classic literary works such as Records of the Historian, Water Margin, Legend of Heroes in the Tang Dynasty, Romance of the Three Kingdoms and Japanese classic The Story of Genji, etc. Also on display were works of the Japa-nese scenery such as Japan's Four Seasons, Snow, Moon and Flowers, etc. and The Red Fujiyama, a work acknowledged by the United Nations.

  14. Space Research Institute (IKI) Exhibition as an Educational Project

    Science.gov (United States)

    Sadovski, Andrei; Antonenko, Elena

    2016-07-01

    The Exhibition "Space Science: Part and Future" in Space Research Institute (IKI) was opened in 2007 in commemoration of the 50th anniversary of the first man-made satellite launch. It covers the latest and the most important findings in space research, shows instruments which are used in space exploration, and presents past, current, and future Russian science missions. Prototypes of space instruments developed by Russian specialists and mockups of spacecraft and spaceships flown to space are displayed, together with information posters, describing space missions, their purposes and results. The Exhibition takes a great part in school space education. Its stuff actively works with schoolchildren, undergraduate students and also makes a great contribution in popularization of space researches. Moreover the possibility to learn about scientific space researches first-hand is priceless. We describe the main parts of the Exhibition and forms of it work and also describe the collaboration with other museums and educational organizations.

  15. One exhibition, many goals. Combining scientific research and risk communication

    Science.gov (United States)

    Charrière, Marie; Bogaard, Thom; Junier, Sandra; Malet, Jean-Philippe; Mostert, Erik

    2015-04-01

    How effective is visual communication to increase awareness of natural hazards and risks? To answer this research question, we developed a research design that was at the same time an experimental setting and an actual communication effort. Throughout the full length of the 2-years project held in the Ubaye valley (southeastern France), we collaborated with local and regional stakeholders (politicians and technicians). During a consultation phase, the communication context was determined, the audience of the project was defined and finally the testing activity-communication effort was determined. We were offered the opportunity to design an exhibition for the local public library. In a consultation phase that corresponded to the design of the exhibition, the stakeholders contributed to its content as well as helping with the funding of the exhibition. Finally, during the experimentation phase, the stakeholders participated in advertising the activity, gathering of participants and designing the scientific survey. In order to assess the effects of the exhibition on risk awareness, several groups of children, teenagers and adults were submitted to a research design, consisting of 1) a pre-test, 2) the visit of the exhibition and 3) a post-test similar to the pre-test. In addition, the children answered a second post-test 3 months after the visit. Close ended questions addressed the awareness indicators mentioned in the literature, i.e. worry level, previous experiences with natural hazards events, exposure to awareness raising, ability to mitigate/respond/prepare, attitude to risk, and demographics. In addition, the post-test included several satisfaction questions concerning the visual tools displayed in the exhibition. A statistical analysis of the changes between the pre- and post- tests (paired t-test, Wilcoxon signed-rank test and bootstrapping) allowed to verify whether the exhibition had an impact on risk awareness or not. In order to deduce which variable

  16. American Telemedicine Association: First China (Tianjin International Telemedicine Technology Exhibition

    Directory of Open Access Journals (Sweden)

    Jordana Bernard

    2014-09-01

    Full Text Available With the support of Tianjin Municipal People’s Government and the People’s Government of Binhai New Area, the “First China (Tianjin International Telemedicine Technology Exhibition” hosted by the American Telemedicine Association (ATA, will be held October 28- 30, 2014 at the Tianjin Binhai International Convention and Exhibition Center. The three day event will feature keynote sessions, concurrent discussion forums, exhibits (e.g., telemedicine, information technology, mHealth, a venture summit, meet-and-greet sessions for international and domestic companies for potential business collaboration, and policy discussions on China healthcare. For registration information: http://www.atacn.org/en/

  17. Wohnlich, Venice Biennial of architecture 2008: Exhibition and its geneses

    Directory of Open Access Journals (Sweden)

    Tomić-Vasiljević Dragana

    2009-01-01

    Full Text Available The procession from the response, that comes in the form of concept, to the entitled exposition theme, via the materialization of that concept in the given or chosen exposition area (technical representation, up to the exhibition realization leads over the numerous accompanying activities that include informative propaganda, the activities concerning the preview and publishing catalogue as an advertising, scientific and educative instrument of the exhibition. The intention of this work is to point at some segments of that general trajectory at the example of Serbian pavilion in Venice biennale of architecture 2008.

  18. TrayGen: Arranging objects for exhibition and packaging

    KAUST Repository

    Yang, Yongliang

    2013-10-01

    We present a framework, called TrayGen, to generate tray designs for the exhibition and packaging of a collection of objects. Based on principles from shape perception and visual merchandising, we abstract a number of design guidelines on how to organize the objects on the tray for the exhibition of their individual features and mutual relationships. Our framework realizes these guidelines by analyzing geometric shapes of the objects and optimizing their arrangement. We demonstrate that the resultant tray designs not only save space, but also highlight the characteristic of each object and the inter-relations between objects. © 2013 The Eurographics Association and John Wiley & Sons Ltd.

  19. 22 CFR 134.12 - Net worth exhibit.

    Science.gov (United States)

    2010-04-01

    ... adjudicative officer in a sealed envelope labeled “Confidential Financial Information”, accompanied by a motion... Information Required From Applicants § 134.12 Net worth exhibit. (a) Each applicant except a qualifed tax... whether the applicant qualifies under the standards in his part. The adjudicative officer may require an...

  20. 15 CFR 18.12 - Net worth exhibit.

    Science.gov (United States)

    2010-01-01

    ... sealed envelope labeled “Confidential Financial Information,” accompanied by a motion to withhold the... Information Required from Applicants § 18.12 Net worth exhibit. (a) Each applicant except a qualified tax... qualifies under the standards in this part. The adjudicative officer may require an applicant to file...

  1. 7 CFR Exhibit B to Subpart B of... - Servicing Company

    Science.gov (United States)

    2010-01-01

    ... of Agriculture, 7 CFR 2.23; delegation of authority by the Assistant Secretary for Rural Development, 7 CFR 2.70) ... 7 Agriculture 12 2010-01-01 2010-01-01 false Servicing Company B Exhibit B to Subpart B of...

  2. 18 CFR 157.16 - Exhibits relating to acquisitions.

    Science.gov (United States)

    2010-04-01

    ..., including engineering, financial accounting, legal, or other services, and the compensation, fees, or other....14(a)(4). (c) Exhibit S—Accounting. A statement showing: (1) The amounts recorded upon the books of... based. (5) The amount at which applicant proposes to record the facilities upon its books; the amount...

  3. Explanatory Parent-Child Conversation Predominates at an Evolution Exhibit

    Science.gov (United States)

    Tare, Medha; French, Jason; Frazier, Brandy N.; Diamond, Judy; Evans, E. Margaret

    2011-01-01

    To investigate how parents support children's learning at an exhibit on evolution, the conversations of 12 families were recorded, transcribed, and coded (6,263 utterances). Children (mean age 9.6 years) and parents visited Explore Evolution, which conveyed current research about the evolution of seven organisms. Families were engaged with the…

  4. The "Gravity-Powered Calculator," a Galilean Exhibit

    Science.gov (United States)

    Cerreta, Pietro

    2014-01-01

    The Gravity-Powered Calculator is an exhibit of the Exploratorium in San Francisco. It is presented by its American creators as an amazing device that extracts the square roots of numbers, using only the force of gravity. But if you analyze his concept construction one can not help but recall the research of Galileo on falling bodies, the inclined…

  5. Highlights of the inauguration ceremony for the new permanent exhibition

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    The new “Universe of Particles" permanent exhibition in the Globe was unveiled this week to its first visitors. On Monday, 28 June, in the presence of representatives of the local authorities, CERN Director-General Rolf Heuer cut the ribbon; on Tuesday, 29 and Wednesday 30 June the Globe's doors remained open for visits by the CERN personnel.   Cutting the ribbon at the inauguration of the Globe's new permanent exhibition At the conclusion of the inauguration ceremony, the Head of the Education Group, Rolf Landua, expressed his satisfaction: “It's wonderful. We are very happy that it has all turned out so well. Now we look forward to lots of visitors.” The exhibition represents a major addition to the tourist destinations in the region and an important tool for the public awareness of science, which could also be useful for schools. “The purpose of the exhibition is to inspire visitors, to arouse their curiosity about science and to motivate them t...

  6. Space Application for ITMA ASIA + CITME 2010 Exhibition Opens

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ 28 April 2009 - Leading textile machinery manufacturers from around the world are invited to apply for space at the second combined ITMA ASIA + CITME exhibition to be held at the Shanghai New International Expo Cen-tre from 22 to 26 June 2010.

  7. 48 CFR 6101.17 - Exhibits [Rule 17].

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Exhibits . 6101.17 Section 6101.17 Federal Acquisition Regulations System CIVILIAN BOARD OF CONTRACT APPEALS, GENERAL SERVICES... original by leave of the Board at any time. The Board may require a party to provide either copies...

  8. Works by Henry Wiss. Collegiate Legacy: Emeritus Faculty Exhibition.

    OpenAIRE

    Wiss, Henry H.

    2014-01-01

    Exhibition of works by College of Architecture and Urban Studies emeritus faculty, celebrating the 50th anniversary of the college. Curated by Truman Capone and Deb Sim. Moss Arts Center, Virginia Tech. HENRY WISS. (left)Mountains. 1950-60. (right) Cowboy. 1950-60. Watercolor on paper. Miller Off Main Gallery/Collection of Robert Miller.

  9. Picasso Exhibition Captures Imagination of Chinese Art Lovers

    Institute of Scientific and Technical Information of China (English)

    SunBin

    2005-01-01

    Against the background of the red imperial city walls in early spring of Beijing,renowned Spanish artist Pablo Picasso sips a mouthful of tea from a Chinese-style cup and gazes at passers-by with his sagacious eyes. That is an image on the thematic poster for the touring Picasso exhibition -- the largest and most valuable ever to visit Asia.

  10. On the Politics of Exhibiting North Korean Art

    NARCIS (Netherlands)

    Shim, David

    2011-01-01

    This essay was written in reaction to the international symposium "Exploring North Korean Arts," which was held on the occasion of the art exhibition "Flowers for Kim Il Sung—Art and Architecture from the DPR Korea," in Vienna on September 3 and 4, 2010. The essay argues that scholars must recognize

  11. The "Gravity-Powered Calculator," a Galilean Exhibit

    Science.gov (United States)

    Cerreta, Pietro

    2014-01-01

    The Gravity-Powered Calculator is an exhibit of the Exploratorium in San Francisco. It is presented by its American creators as an amazing device that extracts the square roots of numbers, using only the force of gravity. But if you analyze his concept construction one can not help but recall the research of Galileo on falling bodies, the inclined…

  12. Du Yuzhou Art Exhibition Will Open in the United Nations

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    From June 5th to 15th 2007,the headquarters of the United Nations will enjoy a show time of Du Yuzhou works,where works of photograph and painting will be exhibited. Mr.Yuzhou Du,President of the China National

  13. "Peace and Progress" Chinese and Japanese Contemporary Calligraphy Exhibition

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>To commemorate the 25th anniversary of the sign-ing of Sino-Japanese Peace and Friendship Treaty, a "Peace and Progress" Chinese and Japanese Contemporary Calligraphy Exhibition jointly sponsored by the CPAFFC, the Chinese Association for Promoting Cultural Development, the Federation of Re-

  14. Curriculum Activities Guide for Natural History Exhibits, Grades K-8.

    Science.gov (United States)

    International Wildlife Museum, Tucson, AZ.

    A natural history museum is a building where animals, plants, minerals, and other things in nature are kept and exhibited for study. This document is a curriculum guide to provide a variety of activities for educators and their students to use not only when visiting the International Wildlife Museum (Tuscon, Arizona), but also with natural history…

  15. A new MOF-505 analog exhibiting high acetylene storage.

    Science.gov (United States)

    Hu, Yunxia; Xiang, Shengchang; Zhang, Wenwei; Zhang, Zhuxiu; Wang, Lei; Bai, Junfeng; Chen, Banglin

    2009-12-28

    A new microporous metal-organic framework Cu(2)(EBTC)(H(2)O)(2) x xG (EBTC = 1,1'-ethynebenzene-3,3',5,5'-tetracarboxylate; G = guest molecule) was rationally designed with a NbO net, exhibiting significantly high acetylene storage of 252 and 160 cm(3) g(-1) at 273 and 295 K under 1 bar, respectively.

  16. Personalising content presentation in museum exhibitions: a case study

    NARCIS (Netherlands)

    Tan, E.S.; Oinonen, K.; Sablatnig, R.; Kampel, M.; Lettner, M.

    2009-01-01

    Museums need to attract more visitors. Personalization of exhibitions is one way to achieve this end. Various options for personalization using information systems have been proposed. A major question is how directive personalization should be. Is visitor satisfaction highest if the system limits th

  17. 7 CFR Exhibits A-B to Subpart G... - [Reserved

    Science.gov (United States)

    2010-01-01

    ... PRIMARILY FOR REAL ESTATE PURPOSES RURAL HOUSING LOANS AND GRANTS Rural Housing Site Loan Policies... 7 Agriculture 12 2010-01-01 2010-01-01 false A Exhibits A-B to Subpart G to Part 1822 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL...

  18. "Four Seasons in Xinjiang" Photographic Exhibition Opened in Beijing

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ On March 26, "Four Seasons in Xinjiang" Photographic ExhibitionXinjiang in a hundred Chinese and Overseas Photographers' Lens was held in the China Millennium Monument, which was co-organized by the State Council Information Office of the P. R. China, China's Photographers'Association and the Government of Xinjiang Uygur Autonomous Region of China.

  19. Exhibition of Origin of Ancient Chinese Characters Held in Japan

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>It was rainy season in Kanazawa, the seat of the government of Ishikawa Prefecture, Japan in the latter half of June. The flowers on both sides of the street were blossoming brightly in the drizzling rain. The exhibition "Origin of Ancient Chinese Characters" was mounted in the Ishikawa Pre-fectural Museum of Art in downtown Kanazawa on June 25.

  20. 7 CFR Exhibit A to Subpart L of... - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true [Reserved] A Exhibit A to Subpart L of Part 1940 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) GENERAL Methodology and Formulas for Allocation of Loan and Grant Program...

  1. Auto Show Exhibition:An Interests-Powered Lever

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Many years in the segment,Li Cheng(not his real name )still can not tell for sure whether the auto development leads auto show exhibitions or the reverse."Both of them have been doing the leadership job,"he said.His passion

  2. 14 CFR Appendix to Part 1274 - Listing of Exhibits

    Science.gov (United States)

    2010-01-01

    ... market, or contracts for transportation or transmission of intelligence. 4. Rights to Inventions Made... Organizations and Small Business Firms Under Government Grants, Contracts and Cooperative Agreements,” and any.... Exhibit B to Part 1274—Reports 1. Property Reporting. As provided in paragraph (f) of § 1274.923,...

  3. Surface Conductive Graphene-Wrapped Micromotors Exhibiting Enhanced Motion.

    Science.gov (United States)

    Ma, Xing; Katuri, Jaideep; Zeng, Yongfei; Zhao, Yanli; Sanchez, Samuel

    2015-10-01

    Surface-conductive Janus spherical motors are fabricated by wrapping silica particles with reduced graphene oxide capped with a thin Pt layer. These motors exhibit a 100% enhanced velocity as compared to standard SiO2 -Pt motors. Furthermore, the versatility of graphene may open up possibilities for a diverse range of applications from active drug delivery systems to water remediation.

  4. Exhibition: Fibre optics, the future is at hand

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    Until 20 June, the Pont de la Machine in Geneva will host an exhibition on fibre optics, sponsored by SIG. CERN, a major user of this technology, was invited to take part with a presentation of some of its scintillating fibre detectors.   The CERN module, designed for the SIG's fibre optics exhibition. Visitors can discover a cosmic ray detector (on the right) and its oscilloscope (on the left), as well as one of the ALFA detector modules (at the back). The Services industriels genevois (SIG), who are in the process of deploying an optical fibre network in Geneva, have decided to showcase this technology with an exhibition entitled “Fibre optique – Le futur à portée de main.” The exhibition, which will be open to the public from 26 April to 20 June, is being held at the Espace ExpoSIG, at the Pont de la Machine in the centre of Geneva. “CERN’s Physics Department was approached by SIG at the start of this year to ...

  5. On the Politics of Exhibiting North Korean Art

    NARCIS (Netherlands)

    Shim, David

    2011-01-01

    This essay was written in reaction to the international symposium "Exploring North Korean Arts," which was held on the occasion of the art exhibition "Flowers for Kim Il Sung—Art and Architecture from the DPR Korea," in Vienna on September 3 and 4, 2010. The essay argues that scholars must recognize

  6. Why Do Agricultural Producers Exhibit at Bread Basket?

    Directory of Open Access Journals (Sweden)

    M. Havlíková

    2015-12-01

    Full Text Available A literature survey proved that trade shows are important marketing tools, enabling sellers to present and test new products, to monitor their competitors, and to establish personal contacts with customers. The paper extends the current research of trade shows by analyzing exhibitors ́ motives for exhibiting. The research is conducted for a traditional international agricultural fair - Bread Basket. Exhibitors, including animal production exhibitors, crop production exhibitors and agriculture technology exhibitors, were offered a list of potential motives for exhibiting and were asked to indicate their agreement (disagreement on a 5-point Likert scale. Subsequently, a factor analysis revealed four key factors for exhibiting, including searching for information and company development, product development, focus on company surroundings and new market possibilities. Finally, exhibitors were surveyed again in order to choose one of these factors to be the most important one for exhibiting. Logistic regression revealed how the specific variables (NACE classification, year of establishment and frequency of exhibitin g influence the selected factors.

  7. Designing Meta Material Slabs Exhibiting Negative Refraction Using Topology Optimization

    DEFF Research Database (Denmark)

    Christiansen, Rasmus Ellebæk; Sigmund, O.

    2016-01-01

    This paper proposes a topology optimization based approach for designing meta materials exhibiting a desired negative refraction with high transmission at a given angle of incidence and frequency. The approach considers a finite slab of meta material consisting of axis-symmetric designable unit...

  8. Properties of epitaxial (210) iron garnet films exhibiting the magnetoelectric effect

    Energy Technology Data Exchange (ETDEWEB)

    Arzamastseva, G. V. [Russian Academy of Sciences, Kotelnikov Institute of Radio Engineering and Electronics, Fryazino Branch (Russian Federation); Balbashov, A. M. [Moscow Power Institute (Russian Federation); Lisovskii, F. V., E-mail: lisf@rambler.ru; Mansvetova, E. G.; Temiryazev, A. G.; Temiryazeva, M. P. [Russian Academy of Sciences, Kotelnikov Institute of Radio Engineering and Electronics, Fryazino Branch (Russian Federation)

    2015-04-15

    The properties of epitaxial magnetic (LuBi){sub 3}(FeGa){sub 5}O{sub 12} iron garnet films grown on (210) substrates, which exhibit the magnetoelectric effect, are experimentally studied. The induced anisotropy and the behavior of the domain structure in the films are investigated in uniform and nonuniform external fields. The existing hypotheses about the nature of the magnetoelectric coupling in such films are critically analyzed.

  9. Properties of epitaxial (210) iron garnet films exhibiting the magnetoelectric effect

    Science.gov (United States)

    Arzamastseva, G. V.; Balbashov, A. M.; Lisovskii, F. V.; Mansvetova, E. G.; Temiryazev, A. G.; Temiryazeva, M. P.

    2015-04-01

    The properties of epitaxial magnetic (LuBi)3(FeGa)5O12 iron garnet films grown on (210) substrates, which exhibit the magnetoelectric effect, are experimentally studied. The induced anisotropy and the behavior of the domain structure in the films are investigated in uniform and nonuniform external fields. The existing hypotheses about the nature of the magnetoelectric coupling in such films are critically analyzed.

  10. Corrosion resistant iron aluminides exhibiting improved mechanical properties and corrosion resistance

    Science.gov (United States)

    Liu, Chain T.; McKamey, Claudette G.; Tortorelli, Peter F.; David, Stan A.

    1994-01-01

    The specification discloses a corrosion-resistant intermetallic alloy comprising, in atomic percent, an FeAl iron aluminide containing from about 30 to about 40% aluminum alloyed with from about 0.01 to 0.4% zirconium and from 0.01 to about 0.8% boron. The alloy exhibits considerably improved room temperature ductility for enhanced usefulness in structural applications. The high temperature strength and fabricability is improved by alloying with molybdenum, carbon, chromium and vanadium.

  11. The Role of the Freelance Curator in an Art Exhibition

    Directory of Open Access Journals (Sweden)

    Ieva VITKAUSKAITĖ

    2015-12-01

    Full Text Available This article analyses the role of the freelance curator in an art exhibition. The first part of the article conceptualises the notion of the modern curator and surveys the categories of curators. The next part of the article surveys the potential models of curation. There are 7 models of curation distinguished: self- reflexive, “sampling”, traditional, decentralisation curation, virtual curation, art – curator, collaborative – curatorial platform. The third part analyses the activity of a freelance curator in the art exhibition, which is divided into five stages, namely preliminary work, preparation and completion of the organisation plan, realisation, operation, dismantling and evaluation. Each stage is described in great detail specifying what works should be carried out by the curator. The final part of the article analyses the remarks of the curators which are then used to derive the formula of successful curatorship.

  12. Performative exhibition and its different modes of experience

    DEFF Research Database (Denmark)

    Schwarzbart, Judith

    different modes of experience, on the one hand, and the social potential in a performative approach to the art exhibition on the other. What are the consequences of decided curatorial presentational formats? When does the format work along or even amplify the artwork, and when does it counteract or directly...... destroy the intentions of the artistic gesture? Performance theory provides us with useful tools to read these performative aspects of exhibitions beyond the performance it self. In her aesthetics of the performative, the theatre scholar Erika Fischer-Lichte shows how experimental performances have...... challenged binaries such as aesthetics – politics/ethics, art – life, symbol – signified, body – mind etc. Through this complex play between ‘former binaries’ – that might now exist concurrent or fully collapse – we can rethink categories like work, audience and space once again....

  13. Exhibition “Space. Information. Research.”

    Directory of Open Access Journals (Sweden)

    Darko Šiško

    2015-06-01

    Full Text Available The exhibition Space. Information. Research. was opened in ZgForum, premises of the City Office of Strategic Planning and Development of the City of Zagreb for communication with professional and the general public on December 18, 2014. The exhibition was opened by deputy mayor of the City of Zagreb, Mrs. Sandra Švaljek Ph.D. and guests were also addressed by Jadranka Veselić Bruvo, Head of the City Office of Strategic Planning and Development and Boris Koružnjak, Dean of the Faculty of Architecture, University of Zagreb. The event was attended by about a hundred invited guests from city administration, City Assembly, academic community, NGOs, private sector, etc.

  14. Wong Leung Kit-Wah and Her Exhibition Tour

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    BEAUTIFUL ladies painted by beautiful woman Annie Wong Leung Kit-Wah, a renowned painter from Hong Kong recently came to Beijing. Upon the first anniversary of Hong Kong’s return to its motherland, Leung held an exhibition of her work at the China Art Gallery. Each piece conveyed her ability to use the unique techniques of Chinese painting to manifest the beauty of women, and her own admiration for women’s qualities: grace and poise, modesty and

  15. art@CMS students' exhibition in Centre des Arts, ECOLINT

    CERN Multimedia

    CMS Communications Group; Geneva, Switzerland; Vaso Sideri

    2015-01-01

    This video documents the outcome of a science and art workshop with the participation of high-school students from the International School of Geneva (ECOLINT). The project was implemented in the framework of art@CMS, an education and outreach programme of the CMS experiment at CERN. In the video, the students present their artworks during the opening of their exhibition at the Centre des Arts of ECOLINT in Geneva.

  16. 1996 SPE annual technical conference and exhibition: Reservoir engineering

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This document contains the Proceedings of the 1996 Society of Petroleum Engineers Annual Technical Conference and Exhibition, Reservoir Engineering section. Topics covered in this section include the evaluation of reservoir engineering and resource management techniques for oil and natural gas fields, description of problems and maintenance techniques for fluid flow in oil wells and pipelines, and technology assessment of enhanced recovery techniques for increasing production from oil and gas fields.

  17. EXHIBITION VISIBILITY; case Moventas Gears Ltd Service WG division

    OpenAIRE

    Elijärvi, Maaret

    2014-01-01

    Wind power business has been developing rapidly during last 10 years and turbines are sprouting up around the globe in record numbers. Moventas Gears Oy is one of the suppliers to the global wind turbine industry. Moventas Gears Oy has two different divisions on wind gear business, new manufacturing (CAP) and service (SER) divisions. The purpose of this work is to improve Moventas Gears Wind Service (SER) marketing visibility and as a target was taken exhibitions. In this work, will be co...

  18. Environmental enrichment for a mixed-species nocturnal mammal exhibit.

    Science.gov (United States)

    Clark, Fay E; Melfi, Vicky A

    2012-01-01

    Environmental enrichment (EE) is an integral aspect of modern zoo animal management but, empirical evaluation of it is biased toward species housed in single-species groups. Nocturnal houses, where several nocturnal species are housed together, are particularly overlooked. This study investigated whether three species (nine-banded armadillos, Dasypus novemcinctus; Senegal bush babies, Galago senegalensis; two-toed sloths, Choloepus didactylus) in the nocturnal house at Paignton Zoo Environmental Park, UK could be enriched using food-based and sensory EE. Subjects were an adult male and female of each species. EE was deemed effective if it promoted target species-typical behaviors, behavioral diversity, and increased use of enriched exhibit zones. Results from generalized linear mixed models demonstrated that food-based EE elicited the most positive behavioral effects across species. One set of food-based EEs (Kong®, termite mound and hanging food) presented together was associated with a significant increase in species-typical behaviors, increased behavioral diversity, and increased use of enriched exhibit zones in armadillos and bush babies. Although one type of sensory EE (scented pine cones) increased overall exhibit use in all species, the other (rainforest sounds) was linked to a significant decrease in species-typical behavior in bush babies and sloths. There were no intra or interspecies conflicts over EE, and commensalism occurred between armadillos and bush babies. Our data demonstrate that simple food-based and sensory EE can promote positive behavioral changes in a mixed-species nocturnal mammal exhibit. We suggest that both food and sensory EE presented concurrently will maximize opportunities for naturalistic activity in all species.

  19. Successful Asia-Pacific Die Casting Industry Exhibition'2005

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Upon the expectation of practitioners in the die casting industry, the Asia-Pacific Die Casting Industry Exhibition'2005, sponsored by Chinese Mechanical Engineering Society (CMES) and China Productivity Promotion Center of Machinery Industry, organized by Foundry Institution of Chinese Mechanical Engineering Society (FICMES) and Productivity Promotion Center of Foundry Industry of China, was successfully held in INTEX Shanghai, China on August 13-17,2005.

  20. Marcel Duchamp and the art of exhibition making

    Directory of Open Access Journals (Sweden)

    Marian Cousijn

    2016-06-01

    Full Text Available Marcel Duchamp made his first readymade over a century ago: a deceptively simple gesture that would turn the art world upside down. The core of artistic practise no longer lies in creating, but in selecting and displaying. But selecting and displaying are also the core tasks of the independent curator. Duchamp already proved in the 1930’s how powerful an exhibition maker can be. A power struggle arose: who gives meaning to art, the curator or the artist?

  1. “Draw me a physicist” exhibition opens

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    From 12 to 23 June, the Globe of Science and Innovation will be hosting the “Draw me a physicist” exhibition: over 160 drawings and definitions that illustrate how children see the world of research.   In a child’s imagination, scientists are colourful, slightly eccentric figures with unusual powers. This is what emerges from the exhibition on the second floor of the Globe of Science and Innovation, opening on 12 June. “Draw me a physicist” brings together 160 drawings and definitions by children about the profession of research scientist. The exhibition is the result of a six-month project by CERN and 20 primary school classes from the Pays de Gex and the communes of Meyrin, Satigny and Vernier. Some 400 schoolchildren aged 9 to 11 were asked in class to make drawings and come up with definitions of a physicist. Subsequently they came to CERN, visited one of the Laboratory’s sites, and met and interviewed some physicists. They used t...

  2. HAPTIC DEVICES AND TACTILE EXPERIENCES IN MUSEUM EXHIBITIONS

    Directory of Open Access Journals (Sweden)

    Radu Comes

    2016-12-01

    Full Text Available Museums all around the globe are starting to adopt advanced technologies that enable the visitors to interact with digital replicas of their collections and artworks. Immersive and interactive virtual reality applications represent one of the most appealing and most used technologies within modern museum exhibitions areas. Using these types of applications the visitors can have access to additional layers of information which can be presented in different languages and presented to the visitor when they demand it using advanced digital interactivity. But the major drawback of these applications is that they don’t allow the users to experience tactile exploration regarding the shapes and ornaments of the cultural heritage artefacts. People are programmed to gather and receive sensory information using their sight, hearing but also using tactile experiences. In order to enable tactile experiences within museum exhibitions, modern technologies such as haptic devices can be installed to enable the visitors to examine the shape of the 3D digital replicas of real artefacts. This paper presents a case study of a haptic device instalment within a museum exhibition that can enable real time tactile exploration of digitized artefacts.

  3. Environmental Salmonella in agricultural fair poultry exhibits in Colorado.

    Science.gov (United States)

    Pabilonia, K L; Cadmus, K J; Lingus, T M; Bolte, D S; Russell, M M; Van Metre, D C; Erdman, M M

    2014-03-01

    Salmonella enterica is a common zoonotic pathogen in humans. Transmission typically occurs through consumption of contaminated food products or contact with infected animals, including poultry or their environment. The objective of this study was to estimate the frequency of Salmonella contamination in the environment in poultry exhibits at agricultural fairs. Samples were collected from cages, feed, floors and tables in the exhibit and cultured for Salmonella. At least one environmental sample was positive for Salmonella in 10 of 11 fairs (91%), and Salmonella was isolated from 28 of 55 environmental samples (50.9%). Eleven different serotypes were detected. Results of this study demonstrate that environmental surfaces at agricultural fairs can be contaminated with Salmonella and could potentially serve as a route of transmission to bird owners and the general public. Poultry owners and the general public should be educated about the risks of Salmonella infection from the poultry exhibit environment. Agricultural fairs should consider instituting policies and practices to improve hygiene and mitigate the risk of zoonotic salmonellosis.

  4. Exhibition: Life and Achievements of Maria Sklodowska-Curie

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    The exhibition "Life and Achievements of Maria Sklodowska-Curie” will be held at CERN (Pas Perdus Corridor, 1st floor, building 61) from the 8 to 24 March.   It is organised under the auspices of the Ambassador R. Henczel, Permanent Representative of the Republic of Poland to the UN Office at Geneva to celebrate the 100th anniversary of the Nobel Prize in Chemistry given to Maria Sklodowska-Curie. The exhibition is also one of the events celebrating the 20th anniversary of Poland joining CERN as a Member State. Maria Sklodowska-Curie, Nobel Prize winner both in physics and chemistry, is one of the greatest scientists of Polish origin. The exhibition, consisting of 20 posters, presents her not only as a brilliant scientist, but also an exceptional woman of great heart, character and organizational talents, sensitive to contemporary problems. The authors are Mrs M. Sobieszczak-Marciniak, the director of the Maria Sklodowska-Curie Museum in Warsaw and Mrs H. Krajewska, the direct...

  5. Stable functional networks exhibit consistent timing in the human brain.

    Science.gov (United States)

    Chapeton, Julio I; Inati, Sara K; Zaghloul, Kareem A

    2017-03-01

    Despite many advances in the study of large-scale human functional networks, the question of timing, stability, and direction of communication between cortical regions has not been fully addressed. At the cellular level, neuronal communication occurs through axons and dendrites, and the time required for such communication is well defined and preserved. At larger spatial scales, however, the relationship between timing, direction, and communication between brain regions is less clear. Here, we use a measure of effective connectivity to identify connections between brain regions that exhibit communication with consistent timing. We hypothesized that if two brain regions are communicating, then knowledge of the activity in one region should allow an external observer to better predict activity in the other region, and that such communication involves a consistent time delay. We examine this question using intracranial electroencephalography captured from nine human participants with medically refractory epilepsy. We use a coupling measure based on time-lagged mutual information to identify effective connections between brain regions that exhibit a statistically significant increase in average mutual information at a consistent time delay. These identified connections result in sparse, directed functional networks that are stable over minutes, hours, and days. Notably, the time delays associated with these connections are also highly preserved over multiple time scales. We characterize the anatomic locations of these connections, and find that the propagation of activity exhibits a preferred posterior to anterior temporal lobe direction, consistent across participants. Moreover, networks constructed from connections that reliably exhibit consistent timing between anatomic regions demonstrate features of a small-world architecture, with many reliable connections between anatomically neighbouring regions and few long range connections. Together, our results demonstrate

  6. 77 FR 54647 - Culturally Significant Objects Imported for Exhibition Determinations: “Manet: Portraying Life”

    Science.gov (United States)

    2012-09-05

    ... Imported for Exhibition Determinations: ``Manet: Portraying Life'' SUMMARY: Notice is hereby given of the... exhibition ``Manet: Portraying Life,'' imported from abroad for temporary exhibition within the United...

  7. Homogeneous illusion device exhibiting transformed and shifted scattering effect

    Science.gov (United States)

    Mei, Jin-Shuo; Wu, Qun; Zhang, Kuang; He, Xun-Jun; Wang, Yue

    2016-06-01

    Based on the theory of transformation optics, a type of homogeneous illusion device exhibiting transformed and shifted scattering effect is proposed in this paper. The constitutive parameters of the proposed device are derived, and full-wave simulations are performed to validate the electromagnetic properties of transformed and shifted scattering effect. The simulation results show that the proposed device not only can visually shift the image of target in two dimensions, but also can visually transform the shape of target. It is expected that such homogeneous illusion device could possess potential applications in military camouflage and other field of electromagnetic engineering.

  8. Mies in Brussels 1934. Synthesis of an Unbuilt Exhibition Architecture

    Directory of Open Access Journals (Sweden)

    Laura Lizondo Sevilla

    2016-04-01

    Full Text Available The article delves into the complex world of exhibition architectures, those whose destiny is reduced to be mounted, exposed and dismantled in a short period of time. A process that allows a quick experience of architecture, bounded in time, and whose experimentation gives rise to the birth of new concepts. The text focuses on the German Pavilion designed by Mies van der Rohe for the Brussels World’s Fair of 1934, his only unbuilt ephemeral architecture due to the political uniqueness of the moment. Now, criticism and the archive allow us to reinterpret its contribution to the history of architecture.

  9. Reservoir engineering. 1995 SPE annual technical conference and exhibition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This document contains the proceedings of the Annual Technical Conference and Exhibition of the Society of Petroleum Engineers which was held on October 22-25, 1995 in Dallas, Texas. This volume contains the presentations regarding Reservoir Engineering. The topics covered in these presentations include: resource management and reservoir engineering of oil, natural gas and gas condensate fields, mathematical models and computerized simulation of fluid flow in reservoir rock, geochemistry of reservoir fluids, and enhanced recovery of oil and natural gas using waterflooding and other secondary recovery methods.

  10. Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries.

    Science.gov (United States)

    Jain, Pritesh P; Leber, Regina; Nagaraj, Chandran; Leitinger, Gerd; Lehofer, Bernhard; Olschewski, Horst; Olschewski, Andrea; Prassl, Ruth; Marsh, Leigh M

    2014-01-01

    Prostacyclin analogues are standard therapeutic options for vasoconstrictive diseases, including pulmonary hypertension and Raynaud's phenomenon. Although effective, these treatment strategies are expensive and have several side effects. To improve drug efficiency, we tested liposomal nanoparticles as carrier systems. In this study, we synthesized liposomal nanoparticles tailored for the prostacyclin analogue iloprost and evaluated their pharmacologic efficacy on mouse intrapulmonary arteries, using a wire myograph. The use of cationic lipids, stearylamine, or 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane (DOTAP) in liposomes promoted iloprost encapsulation to at least 50%. The addition of cholesterol modestly reduced iloprost encapsulation. The liposomal nanoparticle formulations were tested for toxicity and pharmacologic efficacy in vivo and ex vivo, respectively. The liposomes did not affect the viability of human pulmonary artery smooth muscle cells. Compared with an equivalent concentration of free iloprost, four out of the six polymer-coated liposomal formulations exhibited significantly enhanced vasodilation of mouse pulmonary arteries. Iloprost that was encapsulated in liposomes containing the polymer polyethylene glycol exhibited concentration-dependent relaxation of arteries. Strikingly, half the concentration of iloprost in liposomes elicited similar pharmacologic efficacy as nonencapsulated iloprost. Cationic liposomes can encapsulate iloprost with high efficacy and can serve as potential iloprost carriers to improve its therapeutic efficacy.

  11. Parallax Park - A bilingual, outdoor, interactive family exhibit

    Science.gov (United States)

    Hemenway, M. K.; Benedict, G. F.; Preston, S. L.; Armosky, B. J.; Cianciolo, F. W., Jr.; Wetzel, M. N.; Freeman, R.; Ransenberg, A.

    2004-12-01

    We present a design for Parallax Park, an outdoor, interactive family exhibit for McDonald Observatory that will bring the quest for learning about extra-solar planets and the astronomical distance ladder down to Earth for the more than 100,000 visitors who come to the Observatory each year. The Park will teach visitors the basic principles of astrometry. It will concentrate on distance determination and extrasolar planet detection, and emphasize the advantages of space-based astrometric measurements. Visitors will experience parallax by traveling a path around a representation of the Sun, mimicking Earth's orbit, while viewing representations of stars at various distances and in various directions. Concepts include Cepheids as standard candles, the inverse square law, and motion around a center of mass. The exhibit includes interactive components suitable for children's use. Text labels and printed guides, in English and Spanish, will explain how to use the Park to explore the uses of astrometry in modern science. This program was made possible through funding from the Hubble Space Telescope Cycle 11 and 12 Education and Public Outreach Grant Programs. Support from the NASA/JPL Space Interferometry Mission (JPL contract #1227563) is also gratefully acknowledged.

  12. A more modern look for the Council Chamber exhibition

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    When the Council Chamber was renovated, the old photographs displayed on the walls were taken down... they've now been replaced by new panels printed on Plexiglas. The theme of the exhibition is still the history of CERN, but it now features the very latest from graphic design. Fabienne Marcastel, who designed it, tells us more. Two of the new panels recently installed in the Council Chamber. The presentation is simple and elegant. The content is based essentially on the accelerators and the aim of the graphic design is not to attract the public's attention to the panels but rather to provide a pleasant décor for the Chamber's users. "The old photographs stopped at the LEP. The new panels show the history of CERN but also what the Laboratory is like today. Visually, the plan is the starting point, the key to understanding how CERN has changed. It shows how CERN occupies the land it is built on," explains Fabienne Marcastel, the exhibition's graphic designer. The four panels a...

  13. Industrial Exhibition “11th Germany at CERN“

    CERN Multimedia

    FP Department

    2011-01-01

    Administration Building (Bldg. 60/61) Tuesday 25 January: 11a.m. - 5.30 p.m. Wednesday 26 January: 9 a.m. - 5 p.m. The Federal Ministry of Education and Research (BMBF), together with CERN, will hold the Industrial Exhibition “11th Germany at CERN”. Some 30 German companies will present their latest products/technologies related to the field of particle physics and their services to the scientists and buyers of CERN, establish contacts and find out about future purchasing opportunities. On 25 January, Dr. B. Vierkorn-Rudolph of the Federal Ministry of Education and Research and CERN Director-General, Prof. R. D. Heuer, will open the exhibition, followed by a tour of the stands. The main subjects are: electrical engineering, electronics, informatics, mechanical engineering, vacuum & low temperature technologies, instrumentation and safety. CERN staff wishing to obtain information concerning the programme, the exhibitors and their profiles or to get in contact with exhibitors are ...

  14. Industrial Exhibition “11th Germany at CERN“

    CERN Multimedia

    FP Department

    2010-01-01

    Administration Building (Bldg. 60/61) Tuesday 25 January: 11a.m. - 5.30 p.m. Wednesday 26 January: 9 a.m. - 5 p.m. The Federal Ministry of Education and Research (BMBF), together with CERN, will hold the Industrial Exhibition “11th Germany at CERN”. Some 30 German companies will present their latest products/technologies related to the field of particle physics and their services to the scientists and buyers of CERN, establish contacts and find out about future purchasing opportunities. On 25 January, Dr. B. Vierkorn-Rudolph of the Federal Ministry of Education and Research and CERN Director-General, Prof. R. D. Heuer, will open the exhibition, followed by a tour of the stands. The main subjects are: electrical engineering, electronics, informatics, mechanical engineering, vacuum & low temperature technologies, instrumentation and safety. CERN staff wishing to obtain information concerning the programme, the exhibitors and their profiles or to get in contact with exhibitors are r...

  15. Parallax Park - A Bilingual, Outdoor, Interactive Family Exhibit

    Science.gov (United States)

    Benedict, G. F.; Parallax Park Design Team

    2005-10-01

    Parallax Park will be an outdoor, interactive family exhibit for McDonald Observatory. It will bring the quest for extra-solar planets and the astronomical distance scale down to Earth for the more than 100,000 visitors who come to the Observatory each year. The Park will teach visitors the basic principles of astrometry. It will concentrate on distance determination and extrasolar planet detection, and emphasize the advantages of space-based astrometry measurements. Visitors will experience parallax by traveling a path around a representation of the Sun, mimicking Earth's orbit, while viewing representations of stars at various distances and in various directions. Concepts include parallax, Cepheids as standard candles, the inverse square law, and motion around a center of mass. The exhibit includes interactive components suitable for children's use. Text labels and printed guides, in English and Spanish, will explain how to use the Park to explore the uses of astrometry in modern science. In addition auxiliary educational materials that align with the National Science Education Standards will be produced.

  16. Web Exhibition – ATLASES: Poetics, Politics, and Performance

    Directory of Open Access Journals (Sweden)

    Nedjeljko Frančula

    2013-12-01

    Full Text Available ATLASES: Poetics, Politics, and Performance is a web exhibition of atlases from the Special Collections and School of Geographical Sciences of the University of Bristol (http://uobatlases.net/. It includes atlases produced between 1570 to approximately 1970.The exhibition consists of four thematic parts. Renaissance Theatres contains famous and les famous atlases produced between the end of the 16th century to the middle of the 17th century, such as atlases by Ortelius (1574, Camden (1610, Speed (1611 and four atlas tomes by Blaeu (1645. Rhetoric of Truth contains geological and archaeological atlases from the 18th and the beginning of the 19th century. However, Rhetoric of Truth is not only limited to renaissance, but it also encompasses first computer generated atlases, e.g. Atlas of Breeding Birds in England and Ireland (1976 and others. The Colonial Gaze focuses on atlases applied in colonial projects and land exploitation in Africa and the Caribbean Islands, as well as in circulation of race theories in Europe and North America at the end of the 19th century. The last part, National Identities and Conflict explores the role of atlas as a powerful instrument for visualizing conflicts and shaping territorial-political ideas in the 20th century.

  17. Chimpanzees and bonobos exhibit emotional responses to decision outcomes.

    Directory of Open Access Journals (Sweden)

    Alexandra G Rosati

    Full Text Available The interface between cognition, emotion, and motivation is thought to be of central importance in understanding complex cognitive functions such as decision-making and executive control in humans. Although nonhuman apes have complex repertoires of emotional expression, little is known about the role of affective processes in ape decision-making. To illuminate the evolutionary origins of human-like patterns of choice, we investigated decision-making in humans' closest phylogenetic relatives, chimpanzees (Pan troglodytes and bonobos (Pan paniscus. In two studies, we examined these species' temporal and risk preferences, and assessed whether apes show emotional and motivational responses in decision-making contexts. We find that (1 chimpanzees are more patient and more risk-prone than are bonobos, (2 both species exhibit affective and motivational responses following the outcomes of their decisions, and (3 some emotional and motivational responses map onto species-level and individual-differences in decision-making. These results indicate that apes do exhibit emotional responses to decision-making, like humans. We explore the hypothesis that affective and motivational biases may underlie the psychological mechanisms supporting value-based preferences in these species.

  18. Recreational runners with patellofemoral pain exhibit elevated patella water content.

    Science.gov (United States)

    Ho, Kai-Yu; Hu, Houchun H; Colletti, Patrick M; Powers, Christopher M

    2014-09-01

    Increased bone water content resulting from repetitive patellofemoral joint overloading has been suggested to be a possible mechanism underlying patellofemoral pain (PFP). To date, it remains unknown whether persons with PFP exhibit elevated bone water content. The purpose of this study was to determine whether recreational runners with PFP exhibit elevated patella water content when compared to pain-free controls. Ten female recreational runners with a diagnosis of PFP (22 to 39years of age) and 10 gender, age, weight, height, and activity matched controls underwent chemical-shift-encoded water-fat magnetic resonance imaging (MRI) to quantify patella water content (i.e., water-signal fraction). Differences in bone water content of the total patella, lateral aspect of the patella, and medial aspect of the patella were compared between groups using independent t tests. Compared with the control group, the PFP group demonstrated significantly greater total patella bone water content (15.4±3.5% vs. 10.3±2.1%; P=0.001), lateral patella water content (17.2±4.2% vs. 11.5±2.5%; P=0.002), and medial patella water content (13.2±2.7% vs. 8.4±2.3%; Ppatella water content observed in female runners with PFP is suggestive of venous engorgement and elevated extracellular fluid. In turn, this may lead to an increase in intraosseous pressure and pain. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Methylxanthine Inhibit Fungal Chitinases and Exhibit Antifungal Activity

    Science.gov (United States)

    Tsirilakis, Kalliope; Kim, Christy; Vicencio, Alfin G.; Andrade, Christopher; Casadevall, Arturo; Goldman, David L.

    2015-01-01

    Chitinases are necessary for fungal cell wall remodeling and cell replication. Methylxanthines have been shown to competitively inhibit family 18 chitinases in vitro. We sought to determine the effects of methylxanthines on fungal chitinases. Fungi demonstrated variable chitinase activity and incubation with methylxanthines (0.5–10 mM) resulted in a dose-dependent decrease in this activity. All fungi tested, except for Candida spp., demonstrated growth inhibition in the presence of methylxanthines at a concentration of 10 mM. India ink staining demonstrated impaired budding and decreased cell size for methylxanthine-treated Cryptococcus neoformans. C. neoformans and Aspergillus fumigatus treated with pentoxifylline also exhibited abnormal cell morphology. In addition, pentoxifylline-treated C. neoformans exhibited increased susceptibility to calcofluor and a leaky melanin phenotype consistent with defective cell wall function. Our data suggest that a variety of fungi express chitinases and that methylxanthines have antifungal properties related to their inhibition of fungal chitinases. Our results highlight the potential utility of targeting chitinases in the development of novel antifungal therapies. PMID:21968902

  20. Peer review and competition in the Art Exhibition Game.

    Science.gov (United States)

    Balietti, Stefano; Goldstone, Robert L; Helbing, Dirk

    2016-07-26

    To investigate the effect of competitive incentives under peer review, we designed a novel experimental setup called the Art Exhibition Game. We present experimental evidence of how competition introduces both positive and negative effects when creative artifacts are evaluated and selected by peer review. Competition proved to be a double-edged sword: on the one hand, it fosters innovation and product diversity, but on the other hand, it also leads to more unfair reviews and to a lower level of agreement between reviewers. Moreover, an external validation of the quality of peer reviews during the laboratory experiment, based on 23,627 online evaluations on Amazon Mechanical Turk, shows that competition does not significantly increase the level of creativity. Furthermore, the higher rejection rate under competitive conditions does not improve the average quality of published contributions, because more high-quality work is also rejected. Overall, our results could explain why many ground-breaking studies in science end up in lower-tier journals. Differences and similarities between the Art Exhibition Game and scholarly peer review are discussed and the implications for the design of new incentive systems for scientists are explained.

  1. Exhibition | CERN Micro Club | 1-30 September

    CERN Multimedia

    2014-01-01

    The CERN Micro Club (CMC) is organising an exhibition looking back on the origins of the personal computer, also known as the micro-computer, to mark the 60th anniversary of CERN and the club’s own 30th anniversary.   CERN, Building 567, R-021 and R-029 01.09.2014 - 30.09.2014 from 4.00 to 6.00 p.m. The exhibition will be held in the club’s premises (Building 567, rooms R-0121 and R-029) and will be open Mondays to Thursdays from 1 to 30 September 2014. Come and admire, touch and use makes and models that disappeared from the market many years ago, such as Atari, Commodore, Olivetti, DEC, IBM and Apple II and III, all in good working order and installed with applications and games from the period. Club members will be on hand to tell you about these early computers, which had memories of just of a few kilobytes, whereas those of modern computers can reach several gigabytes or even terabytes.

  2. Chronic N-amended soils exhibit an altered bacterial community structure in Harvard Forest, MA, USA.

    Science.gov (United States)

    Turlapati, Swathi A; Minocha, Rakesh; Bhiravarasa, Premsai S; Tisa, Louis S; Thomas, William K; Minocha, Subhash C

    2013-02-01

    At the Harvard Forest, Petersham, MA, the impact of 20 years of annual ammonium nitrate application to the mixed hardwood stand on soil bacterial communities was studied using 16S rRNA genes pyrosequencing. Amplification of 16S rRNA genes was done using DNA extracted from 30 soil samples (three treatments × two horizons × five subplots) collected from untreated (control), low N-amended (50 kg ha(-1) year(-1)) and high N-amended (150 kg ha(-1) year(-1)) plots. A total of 1.3 million sequences were processed using qiime. Although Acidobacteria represented the most abundant phylum based on the number of sequences, Proteobacteria were the most diverse in terms of operational taxonomic units (OTUs). UniFrac analyses revealed that the bacterial communities differed significantly among soil horizons and treatments. Microsite variability among the five subplots was also evident. Nonmetric multidimensional scaling ordination of normalized OTU data followed by permutational manova further confirmed these observations. Richness indicators and indicator species analyses revealed higher bacterial diversity associated with N amendment. Differences in bacterial diversity and community composition associated with the N treatments were also observed at lower phylogenetic levels. Only 28-35% of the 6 936 total OTUs identified were common to three treatments, while the rest were specific to one treatment or common to two.

  3. Chronic N-amended soils exhibit an altered bacterial community structure in Harvard Forest, MA, USA

    Science.gov (United States)

    Swathi A. Turlapati; Rakesh Minocha; Premsai S. Bhiravarasa; Louise S. Tisa; William K. Thomas; Subhash C. Minocha

    2013-01-01

    At the Harvard Forest, Petersham, MA, the impact of 20 years of annual ammonium nitrate application to the mixed hardwood stand on soil bacterial communities was studied using 16S rRNA genes pyrosequencing. Amplification of 16S rRNA genes was done using DNA extracted from 30 soil samples (three treatments x two horizons x five subplots) collected from untreated (...

  4. The Zen of Magic Squares, Circles, and Stars An Exhibition of Surprising Structures across Dimensions

    CERN Document Server

    Pickover, Clifford A

    2011-01-01

    Humanity's love affair with mathematics and mysticism reached a critical juncture, legend has it, on the back of a turtle in ancient China. As Clifford Pickover briefly recounts in this enthralling book, the most comprehensive in decades on magic squares, Emperor Yu was supposedly strolling along the Yellow River one day around 2200 B.C. when he spotted the creature: its shell had a series of dots within squares. To Yu's amazement, each row of squares contained fifteen dots, as did the columns and diagonals. When he added any two cells opposite along a line through the center square, like 2 a

  5. Targeted Mybpc3 Knock-Out Mice with Cardiac Hypertrophy Exhibit Structural Mitral Valve Abnormalities

    Directory of Open Access Journals (Sweden)

    Daniel P. Judge

    2015-04-01

    Full Text Available MYBPC3 mutations cause hypertrophic cardiomyopathy, which is frequently associated with mitral valve (MV pathology. We reasoned that increased MV size is caused by localized growth factors with paracrine effects. We used high-resolution echocardiography to compare Mybpc3-null, heterozygous, and wild-type mice (n = 84, aged 3–6 months and micro-CT for MV volume (n = 6, age 6 months. Mybpc3-null mice showed left ventricular hypertrophy, dilation, and systolic dysfunction compared to heterozygous and wild-type mice, but no systolic anterior motion of the MV or left ventricular outflow obstruction. Compared to wild-type mice, echocardiographic anterior leaflet length (adjusted for left ventricular size was greatest in Mybpc3-null mice (1.92 ± 0.08 vs. 1.72 ± 0.08 mm, p < 0.001, as was combined leaflet thickness (0.23 ± 0.04 vs. 0.15 ± 0.02 mm, p < 0.001. Micro-CT analyses of Mybpc3-null mice demonstrated increased MV volume (0.47 ± 0.06 vs. 0.15 ± 0.06 mm3, p = 0.018 and thickness (0.35 ± 0.04 vs. 0.12 ± 0.04 mm, p = 0.002, coincident with increased markers of TGFβ activity compared to heterozygous and wild-type littermates. Similarly, excised MV from a patient with MYBPC3 mutation showed increased TGFβ activity. We conclude that MYBPC3 deficiency causes hypertrophic cardiomyopathy with increased MV leaflet length and thickness despite the absence of left ventricular outflow-tract obstruction, in parallel with increased TGFβ activity. MV changes in hypertrophic cardiomyopathy may be due to paracrine effects, which represent targets for therapeutic studies.

  6. Simulation of Structures Exhibiting Instability Under Thermal-Mechanical Transient Loading

    Science.gov (United States)

    2015-08-25

    nx ) 1 ¥ å , u0 (x) = b n sin( nx ) 1 ¥ å , q = qn sin( nx ) 1 ¥ å , (5...qn = 2 p q sin( nx )dx 0 p ò (6) Rn = 0 (a n - b n )n 4 + pn 2a n - qn = 0, n = 1,2,... (7) K nm = ¶Rn ¶a m = n 2m 2 2 a na m + n 2 (n 2 + p)d nm , n...exists on the equilibrium path. The u(x) = a n sin( nx ) 1 ¥ å , u0 (x) = b n sin( nx ) 1 ¥ å , q = qn sin( nx ) 1 ¥ å , (26) qn = 2 p qd (x - p 2 )sin( nx )dx

  7. Structural mutants of dengue virus 2 transmembrane domains exhibit host-range phenotype

    Directory of Open Access Journals (Sweden)

    Thomas Gwynneth S

    2011-06-01

    Full Text Available Abstract Background There are over 700 known arboviruses and at least 80 immunologically distinct types that cause disease in humans. Arboviruses are transmitted among vertebrates by biting insects, chiefly mosquitoes and ticks. These viruses are widely distributed throughout the world, depending on the presence of appropriate hosts (birds, horses, domestic animals, humans and vectors. Mosquito-borne arboviruses present some of the most important examples of emerging and resurgent diseases of global significance. Methods A strategy has been developed by which host-range mutants of Dengue virus can be constructed by generating deletions in the transmembrane domain (TMD of the E glycoprotein. The host-range mutants produced and selected favored growth in the insect hosts. Mouse trials were conducted to determine if these mutants could initiate an immune response in an in vivo system. Results The DV2 E protein TMD defined as amino acids 452SWTMKILIGVIITWIG467 was found to contain specific residues which were required for the production of this host-range phenotype. Deletion mutants were found to be stable in vitro for 4 sequential passages in both host cell lines. The host-range mutants elicited neutralizing antibody above that seen for wild-type virus in mice and warrant further testing in primates as potential vaccine candidates. Conclusions Novel host-range mutants of DV2 were created that have preferential growth in insect cells and impaired infectivity in mammalian cells. This method for creating live, attenuated viral mutants that generate safe and effective immunity may be applied to many other insect-borne viral diseases for which no current effective therapies exist.

  8. Structural mutants of dengue virus 2 transmembrane domains exhibit host-range phenotype

    OpenAIRE

    2011-01-01

    Abstract Background There are over 700 known arboviruses and at least 80 immunologically distinct types that cause disease in humans. Arboviruses are transmitted among vertebrates by biting insects, chiefly mosquitoes and ticks. These viruses are widely distributed throughout the world, depending on the presence of appropriate hosts (birds, horses, domestic animals, humans) and vectors. Mosquito-borne arboviruses present some of the most important examples of emerging and resurgent diseases o...

  9. Dual-Use Space Technology Transfer Conference and Exhibition. Volume 1

    Science.gov (United States)

    Krishen, Kumar (Compiler)

    1994-01-01

    This document contains papers presented at the Dual-Use Space Technology Transfer Conference and Exhibition held at the Johnson Space Center February 1-3, 1994. Possible technology transfers covered during the conference were in the areas of information access; innovative microwave and optical applications; materials and structures; marketing and barriers; intelligent systems; human factors and habitation; communications and data systems; business process and technology transfer; software engineering; biotechnology and advanced bioinstrumentation; communications signal processing and analysis; new ways of doing business; medical care; applications derived from control center data systems; human performance evaluation; technology transfer methods; mathematics, modeling, and simulation; propulsion; software analysis and decision tools systems/processes in human support technology; networks, control centers, and distributed systems; power; rapid development perception and vision technologies; integrated vehicle health management; automation technologies; advanced avionics; ans robotics technologies. More than 77 papers, 20 presentations, and 20 exhibits covering various disciplines were presented b experts from NASA, universities, and industry.

  10. Case study of virtual reality in CNC machine tool exhibition

    Directory of Open Access Journals (Sweden)

    Kao Yung-Chou

    2017-01-01

    Full Text Available Exhibition and demonstration are generally used in the promotion and sale-assistance of manufactured products. However, the transportation cost of the real goods from the vender factory to the exposition venue is generally expensive for huge and heavy commodity. With the advancement of computing, graphics, mobile apps, and mobile hardware the 3D visibility technology is getting more and more popular to be adopted in visual-assisted communication such as amusement games. Virtual reality (VR technology has therefore being paid great attention in emulating expensive small and/or huge and heavy equipment. Virtual reality can be characterized as 3D extension with Immersion, Interaction and Imagination. This paper was then be focused on the study of virtual reality in the assistance of CNC machine tool demonstration and exhibition. A commercial CNC machine tool was used in this study to illustrate the effectiveness and usability of using virtual reality for an exhibition. The adopted CNC machine tool is a large and heavy mill-turn machine with the width up to eleven meters and weighted about 35 tons. A head-mounted display (HMD was attached to the developed VR CNC machine tool for the immersion viewing. A user can see around the 3D scene of the large mill-turn machine and the operation of the virtual CNC machine can be actuated by bare hand. Coolant was added to demonstrate more realistic operation while collision detection function was also added to remind the operator. The developed VR demonstration system has been presented in the 2017 Taipei International Machine Tool Show (TIMTOS 2017. This case study has shown that young engineers and/or students are very impressed by the VR-based demonstration while elder persons could not adapt themselves easily to the VR-based scene because of eyesight issues. However, virtual reality has successfully being adopted and integrated with the CNC machine tool in an international show. Another machine tool on

  11. Engagement In Climate Change Awareness Through Art Exhibitions

    Science.gov (United States)

    Burko, D.

    2016-12-01

    Artists such as myself can influence the public discourse on climate change through compelling imagery transcending data and language. I will speak specifically to how I communicate scientific research to diverse populations by making those issues personal, visceral, and actionable.I began integrating scientific visual data into my aesthetic practice ten years ago by first utilizing archival evidence in the form of repeats, geological charts of recessional lines, graphs, symbols and Landsat maps. I continue to develop visual strategies delivering information on an emotional/non-verbal level. In the past 4 years, I have added the most dramatic layer to my creative process: bearing witness. I've been to the three largest ice fields in the world: Greenland, Antarctica and Argentina's Patagonia, observing the unprecedented pace of glacial melt. The emotional significance of actually being there as an artist is immense. Those expeditions impact my practice, leading to exhibitions that open a dialog with an audience not initially interested in science. In the past 5 years my work has appeared in 6 solo and 19 group exhibits all devoted to the environment. I make myself present in universities, museums and galleries to explain what the images are about. I require universities to include a public component: an all-college lecture or panel where the geography/environmental/sociology/geology departments participate with broad student involvement. I believe that such endeavors are worthwhile and can be models for further efforts to educate an unsuspecting audience. Artists can bridge the gap communicating to a public of art appreciators, nonscientists - how easy it is to understand geology and global warming. This social engagement can even inspire and result in attitudinal changes. A viewer's initial emotional response to my large paintings and photographs evolves into comprehension as a dialog about their content is revealed. By sharing my personal story about my

  12. Designing Meta Material Slabs Exhibiting Negative Refraction Using Topology Optimization

    DEFF Research Database (Denmark)

    Christiansen, Rasmus Ellebæk; Sigmund, O.

    2016-01-01

    This paper proposes a topology optimization based approach for designing meta materials exhibiting a desired negative refraction with high transmission at a given angle of incidence and frequency. The approach considers a finite slab of meta material consisting of axis-symmetric designable unit...... cells subjected to an exterior field. The unit cell is designed to achieve the desired properties based on tailoring the response of the meta material slab underthe exterior field. The approach is directly applicable to physical problems modeled by the Helmholtz equation, such as acoustic, elastic...... and electromagnetic wave problems. Acoustic meta materials with unit cell size on the order of half the wave length are considered as examples. Optimized designs are presented and their performance under varying frequency and angle of incidence is investigated....

  13. Bougainvillea spectabilis Exhibits Antihyperglycemic and Antioxidant Activities in Experimental Diabetes.

    Science.gov (United States)

    Chauhan, Pratibha; Mahajan, Sunil; Kulshrestha, Archana; Shrivastava, Sadhana; Sharma, Bechan; Goswamy, H M; Prasad, G B K S

    2016-07-01

    The study investigates the effects of aqueous extract of Bougainvillea spectabilis leaves on blood glucose, glycosylated hemoglobin, lipid profile, oxidative stress, and on DNA damage, if any, as well as on liver and kidney functions in streptozotocin-induced diabetes in Wistar rats. Daily administration of the aqueous extract of B spectabilis leaves for 28 days resulted in significant reduction in hyperglycemia and hyperlipidemia as evident from restoration of relevant biochemical markers following extract administration. The extract also exhibited significant antioxidant activity as evidenced from the enzymatic and nonenzymatic responses and DNA damage markers. The extract restored kidney and liver functions to normal and proved to be nontoxic. A marked improvement in the histological changes of tissues was also observed. The present study documented antihyperglycemic, antihyperlipidemic, and antioxidative potentials of the aqueous extract of B spectabilis leaves without any toxicity in streptozotocin-treated Wistar rats.

  14. “Nantong Through Eyes of Foreigners” Photo Exhibition Held

    Institute of Scientific and Technical Information of China (English)

    ZhaoLinjin

    2004-01-01

    Nantong is one of the first 14 coastal cities in China opened to the outside world. In the past 20 years, foreign friends have come to Nantong one batch after another to conduct studieson investment environment, do business, teach and carry out researches, go sightseeing, etc.They, with a friendly as well as critical eye, look at the natural environment, landscape, economic development, social physiognomy, life and customs of the city. To enrich the cultural life of foreign friends working and residing in Nantong and enhance communication and exchanges between them and the local people, the Foreign Affairs Office of the Nantong City Government,the Nantong City People's Association for Friendship with Foreign Countries, the Nantong Daily, the Industrial and Commercial Bank of Nantong and the Nantong Photographers' Association jointly sponsored a photo exhibition entitled “Nantong Through the Eyes of Foreigners”.

  15. A Novel Infrared Radiant Glaze Exhibiting Antibacterialand Antifungal Functions

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Infrared radiant powder was synthesized by conventional ceramic processing techniques by using Fe2O3, MnO2, CuO, Co2O3 and kaolin as raw materials. A novel infrared radiant glaze was developed by introducing the infrared radiant powder into glazing as a functional additive. Infrared radiant characteristics of the powder and the glaze were investigated. The optimum content of infrared radiant powder in glazing was ascertained to be 5%. The infrared radiant glaze exhibits significant antibacterial and antifungal functions due to the thermal effect of infrared radiation. Antibacterial percentages of the glaze reach 91%-100% when Escherichia coli, Staphylococcus aureus and Bacillus subtilis are used as model bacterium respectively, while antifungal percentage of the glaze exceeds 95% when Penicillum citrinum is used as model fungus.

  16. Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries

    Directory of Open Access Journals (Sweden)

    Jain PP

    2014-07-01

    Full Text Available Pritesh P Jain,1 Regina Leber,1,2 Chandran Nagaraj,1 Gerd Leitinger,3 Bernhard Lehofer,4 Horst Olschewski,1,5 Andrea Olschewski,1,6 Ruth Prassl,1,4 Leigh M Marsh11Ludwig Boltzmann Institute for Lung Vascular Research, 2Biophysics Division, Institute of Molecular Biosciences, University of Graz, 3Research Unit Electron Microscopic Techniques, Institute of Cell Biology, Histology, and Embryology, 4Institute of Biophysics, 5Division of Pulmonology, Department of Internal Medicine, 6Department of Anesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, AustriaAbstract: Prostacyclin analogues are standard therapeutic options for vasoconstrictive diseases, including pulmonary hypertension and Raynaud’s phenomenon. Although effective, these treatment strategies are expensive and have several side effects. To improve drug efficiency, we tested liposomal nanoparticles as carrier systems. In this study, we synthesized liposomal nanoparticles tailored for the prostacyclin analogue iloprost and evaluated their pharmacologic efficacy on mouse intrapulmonary arteries, using a wire myograph. The use of cationic lipids, stearylamine, or 1,2-di-(9Z-octadecenoyl-3-trimethylammonium-propane (DOTAP in liposomes promoted iloprost encapsulation to at least 50%. The addition of cholesterol modestly reduced iloprost encapsulation. The liposomal nanoparticle formulations were tested for toxicity and pharmacologic efficacy in vivo and ex vivo, respectively. The liposomes did not affect the viability of human pulmonary artery smooth muscle cells. Compared with an equivalent concentration of free iloprost, four out of the six polymer-coated liposomal formulations exhibited significantly enhanced vasodilation of mouse pulmonary arteries. Iloprost that was encapsulated in liposomes containing the polymer polyethylene glycol exhibited concentration-dependent relaxation of arteries. Strikingly, half the concentration of iloprost in liposomes elicited

  17. Ultralyophobic oxidized aluminum surfaces exhibiting negligible contact angle hysteresis.

    Science.gov (United States)

    Hozumi, Atsushi; McCarthy, Thomas J

    2010-02-16

    Ultralyophobic oxidized aluminum surfaces exhibiting negligible contact angle hysteresis for probe liquids were prepared by chemical vapor deposition (CVD) of bis((tridecafluoro-1,1,2,2,-tetrahydrooctyl)-dimethylsiloxy)methylsilane (CF(3)(CF(2))(5)CH(2)CH(2)Si(CH(3))(2)O)(2)SiCH(3)H, (R(F)Si(Me)(2)O)(2)SiMeH). Oxidized aluminum surfaces were prepared by photooxidation/cleaning of sputter-coated aluminum on silicon wafers (Si/Al(Al(2)(O(3)))) using oxygen plasma. X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM) confirmed that this facile CVD method produces a monolayer with a thickness of 1.1 nm on the Si/Al(Al(2)(O(3))) surface without a discernible change in surface morphology. After monolayer deposition, the hydrophilic Si/Al(Al(2)(O(3))) surface became both hydrophobic and oleophobic and exhibited essentially no contact angle hysteresis for water and n-hexadecane (advancing/receding contact angles (theta(A)/theta(R)) = 110 degrees/109 degrees and 52 degrees/50 degrees, respectively). Droplets move very easily on this surface and roll off of slightly tilted surfaces, independently of the contact angle (which is a practical definition of ultralyophobic). A conventional fluoroalkylsilane monolayer was also prepared from 1H,1H,2H,2H-perfluorodecyltrimethoxysilane (CF(3)(CF(2))(7)CH(2)CH(2)Si(OCH(3))(3), R(F)Si(OMe)(3)) for comparison. The theta(A)/theta(R) values for water and n-hexadecane are 121 degrees/106 degrees and 76 degrees/71 degrees, respectively. The larger hysteresis values indicate the "pinning" of probe liquids, even though advancing contact angles are larger than those of the (R(F)Si(Me)(2)O)(2)SiMeH-derived monolayers. The (R(F)Si(Me)(2)O)(2)SiMeH-derived monolayers have excellent hydrolytic stability in water. We propose that the (R(F)Si(Me)(2)O)(2)SiMeH-derived monolayers are flexible and liquidlike and that drops in contact with these surfaces experience very low energy barriers between metastable states, leading to the

  18. How Can Museum Exhibits Enhance Earthquake and Tsunami Hazard Resiliency?

    Science.gov (United States)

    Olds, S. E.

    2015-12-01

    Creating a natural disaster-ready community requires interoperating scientific, technical, and social systems. In addition to the technical elements that need to be in place, communities and individuals need to be prepared to react when a natural hazard event occurs. Natural hazard awareness and preparedness training and education often takes place through informal learning at science centers and formal k-12 education programs as well as through awareness raising via strategically placed informational tsunami warning signs and placards. Museums and science centers are influential in raising science literacy within a community, however can science centers enhance earthquake and tsunami resiliency by providing hazard science content and preparedness exhibits? Museum docents and informal educators are uniquely situated within the community. They are transmitters and translators of science information to broad audiences. Through interaction with the public, docents are well positioned to be informants of the knowledge beliefs, and feelings of science center visitors. They themselves are life-long learners, both constantly learning from the museum content around them and sharing this content with visitors. They are also members of a community where they live. In-depth interviews with museum informal educators and docents were conducted at a science center in coastal Pacific Northwest. This region has a potential to be struck by a great 9+ Mw earthquake and subsequent tsunami. During the interviews, docents described how they applied learning from natural hazard exhibits at a science visitor center to their daily lives. During the individual interviews, the museum docents described their awareness (knowledge, attitudes, and behaviors) of natural hazards where they live and work, the feelings evoked as they learned about their hazard vulnerability, the extent to which they applied this learning and awareness to their lives, such as creating an evacuation plan, whether

  19. Metformin exhibits preventive and therapeutic efficacy against experimental cystic echinococcosis

    Science.gov (United States)

    Loos, Julia A.; Dávila, Valeria A.; Rodrígues, Christian R.; Petrigh, Romina; Zoppi, Jorge A.; Crocenzi, Fernando A.; Cumino, Andrea C.

    2017-01-01

    Metformin (Met) is an anti-hyperglycemic and potential anti-cancer agent which may exert its anti-proliferative effects via the induction of energetic stress. In this study we investigated the in vitro and in vivo efficacy of Met against the larval stage of Echinococcus granulosus. Metformin showed significant dose- and time-dependent killing effects on in vitro cultured protoscoleces and metacestodes. Notably, the combination of Met together with the minimum effective concentration of ABZSO had a synergistic effect after days 3 and 12 on metacestodes and protoscoleces, respectively. Oral administration of Met (50 mg/kg/day) in E. granulosus-infected mice was highly effective in reducing the weight and number of parasite cysts, yet its combination with the lowest recommended dose of ABZ (5 mg/kg/day) was even more effective. Coincidentally, intracystic Met accumulation was higher in animals treated with both drugs compared to those administered Met alone. Furthermore, the safe plant-derived drug Met exhibited remarkable chemopreventive properties against secondary hydatidosis in mice. In conclusion, based on our experimental data, Met emerges as a promising anti-echinococcal drug as it has proven to efficiently inhibit the development and growth of the E. granulosus larval stage and its combination with ABZ may improve the current anti-parasitic therapy. PMID:28182659

  20. Apoptotic HPV positive cancer cells exhibit transforming properties.

    Directory of Open Access Journals (Sweden)

    Emilie Gaiffe

    Full Text Available Previous studies have shown that DNA can be transferred from dying engineered cells to neighboring cells through the phagocytosis of apoptotic bodies, which leads to cellular transformation. Here, we provide evidence of an uptake of apoptotic-derived cervical cancer cells by human mesenchymal cells. Interestingly, HeLa (HPV 18+ or Ca Ski (HPV16+ cells, harboring integrated high-risk HPV DNA but not C-33 A cells (HPV-, were able to transform the recipient cells. Human primary fibroblasts engulfed the apoptotic bodies effectively within 30 minutes after co-cultivation. This mechanism is active and involves the actin cytoskeleton. In situ hybridization of transformed fibroblasts revealed the presence of HPV DNA in the nucleus of a subset of phagocytosing cells. These cells expressed the HPV16/18 E6 gene, which contributes to the disruption of the p53/p21 pathway, and the cells exhibited a tumorigenic phenotype, including an increased proliferation rate, polyploidy and anchorage independence growth. Such horizontal transfer of viral oncogenes to surrounding cells that lack receptors for HPV could facilitate the persistence of the virus, the main risk factor for cervical cancer development. This process might contribute to HPV-associated disease progression in vivo.

  1. Isolation and characterization of novel bacterial strains exhibiting ligninolytic potential

    Directory of Open Access Journals (Sweden)

    Bandounas Luaine

    2011-10-01

    Full Text Available Abstract Background To expand on the range of products which can be obtained from lignocellulosic biomass, the lignin component should be utilized as feedstock for value-added chemicals such as substituted aromatics, instead of being incinerated for heat and energy. Enzymes could provide an effective means for lignin depolymerization into products of interest. In this study, soil bacteria were isolated by enrichment on Kraft lignin and evaluated for their ligninolytic potential as a source of novel enzymes for waste lignin valorization. Results Based on 16S rRNA gene sequencing and phenotypic characterization, the organisms were identified as Pandoraea norimbergensis LD001, Pseudomonas sp LD002 and Bacillus sp LD003. The ligninolytic capability of each of these isolates was assessed by growth on high-molecular weight and low-molecular weight lignin fractions, utilization of lignin-associated aromatic monomers and degradation of ligninolytic indicator dyes. Pandoraea norimbergensis LD001 and Pseudomonas sp. LD002 exhibited best growth on lignin fractions, but limited dye-decolourizing capacity. Bacillus sp. LD003, however, showed least efficient growth on lignin fractions but extensive dye-decolourizing capacity, with a particular preference for the recalcitrant phenothiazine dye class (Azure B, Methylene Blue and Toluidene Blue O. Conclusions Bacillus sp. LD003 was selected as a promising source of novel types of ligninolytic enzymes. Our observations suggested that lignin mineralization and depolymerization are separate events which place additional challenges on the screening of ligninolytic microorganisms for specific ligninolytic enzymes.

  2. Captives of Narrative Scandinavian Museum Exhibits and Polar Ambitions

    Directory of Open Access Journals (Sweden)

    Anders Houltz

    2010-12-01

    Full Text Available This article compares the histories of two museums of polar exploration, both founded in the 1930s but based on well-known expeditions dating back to the decades around 1900. The first is the Fram Museum in Oslo, centered around the famous Norwegian polar ship, the second is the Andrée Museum in Gränna, com-bining accounts of the ill-fated balloon expedition with a polar centre reflecting more recent polar research activities. The aim of the article is to analyze the relationship between museum and narra-tive. Museums are shapers of narrative but at the same time shaped by the narra-tives they relate. The article explores the symbolic and medialized dimensions of polar research, expressed in museums, as well as the way in which museums in-terrelate with national identities and self-images. What does it mean to be a modern polar nation? And how is such an identity expressed in cultural terms? In which ways can museum institutions and exhibi-tions be used as means for such expressions? And how do “the grand narratives” of Sweden and Norway relate to the epic representations of polar activities, pre-sented by the museums?

  3. Piper betle extracts exhibit antitumor activity by augmenting antioxidant potential.

    Science.gov (United States)

    Alam, Badrul; Majumder, Rajib; Akter, Shahina; Lee, Sang-Han

    2015-02-01

    The present study was conducted to evaluate the methanolic extract of Piper betle leaves (MPBL) and its organic fractions with regard to antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice and to confirm their antioxidant activities. At 24 h post-intraperitoneal inoculation of tumor cells into mice, extracts were administered at 25, 50 and 100 mg/kg body weight for nine consecutive days. The antitumor effects of the extracts were then assessed according to tumor volume, packed cell count, viable and non-viable tumor cell count, median survival time and increase in life span of EAC-bearing mice. Next, hematological profiles and serum biochemical parameters were calculated, and antioxidant properties were assessed by estimating lipid peroxidation, reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) levels. MPBL and the ethylacetate fraction (EPBL) at a dose of 100 mg/kg induced a significant decrease in tumor volume, packed cell volume and viable cell count and increased the life span of the EAC-bearing mice (PPiper betle extracts exhibit significant antitumor activity, which may be attributed to the augmentation of endogenous antioxidant potential.

  4. Bonobos and chimpanzees exhibit human-like framing effects.

    Science.gov (United States)

    Krupenye, Christopher; Rosati, Alexandra G; Hare, Brian

    2015-02-01

    Humans exhibit framing effects when making choices, appraising decisions involving losses differently from those involving gains. To directly test for the evolutionary origin of this bias, we examined decision-making in humans' closest living relatives: bonobos (Pan paniscus) and chimpanzees (Pan troglodytes). We presented the largest sample of non-humans to date (n = 40) with a simple task requiring minimal experience. Apes made choices between a 'framed' option that provided preferred food, and an alternative option that provided a constant amount of intermediately preferred food. In the gain condition, apes experienced a positive 'gain' event in which the framed option was initially presented as one piece of food but sometimes was augmented to two. In the loss condition, apes experienced a negative 'loss' event in which they initially saw two pieces but sometimes received only one. Both conditions provided equal pay-offs, but apes chose the framed option more often in the positive 'gain' frame. Moreover, male apes were more susceptible to framing than were females. These results suggest that some human economic biases are shared through common descent with other apes and highlight the importance of comparative work in understanding the origins of individual differences in human choice.

  5. Mature adipocyte-derived dedifferentiated fat cells exhibit multilineage potential.

    Science.gov (United States)

    Matsumoto, Taro; Kano, Koichiro; Kondo, Daisuke; Fukuda, Noboru; Iribe, Yuji; Tanaka, Nobuaki; Matsubara, Yoshiyuki; Sakuma, Takahiro; Satomi, Aya; Otaki, Munenori; Ryu, Jyunnosuke; Mugishima, Hideo

    2008-04-01

    When mature adipocytes are subjected to an in vitro dedifferentiation strategy referred to as ceiling culture, these mature adipocytes can revert to a more primitive phenotype and gain cell proliferative ability. We refer to these cells as dedifferentiated fat (DFAT) cells. In the present study, we examined the multilineage differentiation potential of DFAT cells. DFAT cells obtained from adipose tissues of 18 donors exhibited a fibroblast-like morphology and sustained high proliferative activity. Flow cytometric analysis revealed that DFAT cells comprised a highly homogeneous cell population compared with that of adipose-derived stem/stromal cells (ASCs), although the cell-surface antigen profile of DFAT cells was very similar to that of ASCs. DFAT cells lost expression of mature adipocytes marker genes but retained or gained expression of mesenchymal lineage-committed marker genes such as peroxisome proliferator-activated receptor gamma (PPARgamma), RUNX2, and SOX9. In vitro differentiation analysis revealed that DFAT cells could differentiate into adipocytes, chondrocytes, and osteoblasts under appropriate culture conditions. DFAT cells also formed osteoid matrix when implanted subcutaneously into nude mice. In addition, clonally expanded porcine DFAT cells showed the ability to differentiate into multiple mesenchymal cell lineages. These results indicate that DFAT cells represent a type of multipotent progenitor cell. The accessibility and ease of culture of DFAT cells support their potential application for cell-based therapies.

  6. Different proteolipid protein mutants exhibit unique metabolic defects

    Directory of Open Access Journals (Sweden)

    Maik Hüttemann

    2009-08-01

    Full Text Available PMD (Pelizaeus–Merzbacher disease, a CNS (central nervous system disease characterized by shortened lifespan and severe neural dysfunction, is caused by mutations of the PLP1 (X-linked myelin proteolipid protein gene. The majority of human PLP1 mutations are caused by duplications; almost all others are caused by missense mutations. The cellular events leading to the phenotype are unknown. The same mutations in non-humans make them ideal models to study the mechanisms that cause neurological sequelae. In the present study we show that mice with Plp1 duplications (Plp1tg have major mitochondrial deficits with a 50% reduction in ATP, a drastically reduced mitochondrial membrane potential and increased numbers of mitochondria. In contrast, the jp (jimpy mouse with a Plp1 missense mutation exhibits normal mitochondrial function. We show that PLP in the Plp1tg mice and in Plp1-transfected cells is targeted to mitochondria. PLP has motifs permissive for insertion into mitochondria and deletions near its N-terminus prevent its co-localization to mitochondria. These novel data show that Plp1 missense mutations and duplications of the native Plp1 gene initiate uniquely different cellular responses.

  7. Does adsorption in a single nanogroove exhibit hysteresis?

    Science.gov (United States)

    Malijevský, Alexandr

    2012-12-01

    A simple fluid, in a microscopic capillary capped at one end, is studied by means of fundamental measure density functional. The model represents a single, infinitely long nanogroove with long-range wall-fluid attractive (dispersion) forces. It is shown that the presence or absence of hysteresis in adsorption isotherms is determined by wetting properties of the wall as follows: Above wetting temperature, Tw, appropriate to a single wall of the groove, the adsorption is a continuous process corresponding to a rise of a meniscus from the capped to the open end of the groove. For a sufficiently deep capillary, the meniscus rise is shown to be a steep, yet continuous process taking place near the capillary condensation of a corresponding slit. However, for temperatures lower than Tw the condensation exhibits a first-order transition accompanied by hysteresis of the adsorption isotherm. Finally, it is shown that hysteresis may occur even for T > Tw as a consequence of prewetting on the side and bottom walls of the groove.

  8. Metallic zinc exhibits optimal biocompatibility for bioabsorbable endovascular stents.

    Science.gov (United States)

    Bowen, Patrick K; Guillory, Roger J; Shearier, Emily R; Seitz, Jan-Marten; Drelich, Jaroslaw; Bocks, Martin; Zhao, Feng; Goldman, Jeremy

    2015-11-01

    Although corrosion resistant bare metal stents are considered generally effective, their permanent presence in a diseased artery is an increasingly recognized limitation due to the potential for long-term complications. We previously reported that metallic zinc exhibited an ideal biocorrosion rate within murine aortas, thus raising the possibility of zinc as a candidate base material for endovascular stenting applications. This study was undertaken to further assess the arterial biocompatibility of metallic zinc. Metallic zinc wires were punctured and advanced into the rat abdominal aorta lumen for up to 6.5months. This study demonstrated that metallic zinc did not provoke responses that often contribute to restenosis. Low cell densities and neointimal tissue thickness, along with tissue regeneration within the corroding implant, point to optimal biocompatibility of corroding zinc. Furthermore, the lack of progression in neointimal tissue thickness over 6.5months or the presence of smooth muscle cells near the zinc implant suggest that the products of zinc corrosion may suppress the activities of inflammatory and smooth muscle cells.

  9. Artificially engineered Heusler ferrimagnetic superlattice exhibiting perpendicular magnetic anisotropy

    Science.gov (United States)

    Ma, Q. L.; Zhang, X. M.; Miyazaki, T.; Mizukami, S.

    2015-01-01

    To extend density limits in magnetic recording industry, two separate strategies were developed to build the storage bit in last decade, introduction of perpendicular magnetic anisotropy (PMA) and adoption of ferrimagnetism/antiferromagnetism. Meanwhile, these properties significantly improve device performance, such as reducing spin-transfer torque energy consumption and decreasing signal-amplitude-loss. However, materials combining PMA and antiferromagnetism rather than transition-metal/rare-earth system were rarely developed. Here, we develop a new type of ferrimagnetic superlattice exhibiting PMA based on abundant Heusler alloy families. The superlattice is formed by [MnGa/Co2FeAl] unit with their magnetizations antiparallel aligned. The effective anisotropy (Kueff) over 6 Merg/cm3 is obtained, and the SL can be easily built on various substrates with flexible lattice constants. The coercive force, saturation magnetization and Kueff of SLs are highly controllable by varying the thickness of MnGa and Co2FeAl layers. The SLs will supply a new choice for magnetic recording and spintronics memory application such as magnetic random access memory.

  10. Green light for a permanent exhibition in the Globe

    CERN Document Server

    2008-01-01

    A donation to the Foundation for the Globe of Science and Innovation by ROLEX S.A. marks the first step towards the planned expansion of the Globe’s infrastructure. The Globe: a CERN emblem.Visible from miles away by day and by night, the Globe, the wooden sphere offered to CERN by the Swiss Confederation in 2004, has become one of the symbols of the Organization. Since being opened to the public in September 2005, the Globe has served as a venue for lectures, exhibitions, press and VIP events and workshops for schoolchildren and as a stage for theatre performances on scientific themes. With a view to turning the Globe into a flagship venue for events for the general public, and for interactions between CERN and its public and private partners, two projects are planned for the near future. CERN is receiving support for these ventures from the Foundation for the Globe. Established at the end of 2007, the Foundation’s mission is to ...

  11. Short and long term measures of anxiety exhibit opposite results.

    Directory of Open Access Journals (Sweden)

    Ehud Fonio

    Full Text Available Animal models of human diseases of the central nervous system, generalized anxiety disorder included, are essential for the study of the brain-behavior interface and obligatory for drug development; yet, these models fail to yield new insights and efficacious drugs. By increasing testing duration hundredfold and arena size tenfold, and comparing the behavior of the common animal model to that of wild mice, we raise concerns that chronic anxiety might have been measured at the wrong time, for the wrong duration, and in the wrong animal. Furthermore, the mice start the experimental session with a short period of transient adaptation to the novel environment (habituation period and a long period reflecting the respective trait of the mice. Using common measures of anxiety reveals that mice exhibit opposite results during these periods suggesting that chronic anxiety should be measured during the post-habituation period. We recommend tools for measuring the transient period, and provide suggestions for characterizing the post habituation period.

  12. Cancer cells exhibit clonal diversity in phenotypic plasticity.

    Science.gov (United States)

    Mathis, Robert Austin; Sokol, Ethan S; Gupta, Piyush B

    2017-02-01

    Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain poorly understood. Here we apply DNA barcodes to quantify and track phenotypic plasticity across hundreds of clones in a population of cancer cells exhibiting epithelial or mesenchymal differentiation phenotypes. We find that the epithelial-to-mesenchymal cell ratio is highly variable across the different clones in cancer cell populations, but remains stable for many generations within the progeny of any single clone-with a heritability of 0.89. To estimate the effects of combination therapies on phenotypically heterogeneous tumours, we generated quantitative simulations incorporating empirical data from our barcoding experiments. These analyses indicated that combination therapies which alternate between epithelial- and mesenchymal-specific treatments eventually select for clones with increased phenotypic plasticity. However, this selection could be minimized by increasing the frequency of alternation between treatments, identifying designs that may minimize selection for increased phenotypic plasticity. These findings establish new insights into phenotypic plasticity in cancer, and suggest design principles for optimizing the effectiveness of combination therapies for phenotypically heterogeneous tumours.

  13. A new theory of doped manganites exhibiting colossal magnetoresistance

    Indian Academy of Sciences (India)

    H R Krishnamurthy

    2005-06-01

    Rare earth manganites doped with alkaline earths, namely Re1-AMnO3, exhibit colossal magnetoresistance, metal insulator transitions, competing magnetic, orbital and charge ordering, and many other interesting but poorly understood phenomena. In this article I outline our recent theory based on the idea that in the presence of strong Jahn–Teller, Coulomb and Hund’s couplings present in these materials, the low-energy electronic states dynamically reorganize themselves into two sets: one set (ℓ) which are polaronic, i.e., localized and accompanied by large local lattice distortion, and another (b) which are non-polaronic and band-like. The coexistence of the radically different ℓ and states, and the sensitive dependence of their relative energies and occupation upon doping , temperature , magnetic field , etc., underlies the unique effects seen in manganites. I present results from strong correlation calculations using dynamical mean-field theory and simulations on a new 2-fluid model which accord with a variety of observations.

  14. Artificially engineered Heusler ferrimagnetic superlattice exhibiting perpendicular magnetic anisotropy.

    Science.gov (United States)

    Ma, Q L; Zhang, X M; Miyazaki, T; Mizukami, S

    2015-01-19

    To extend density limits in magnetic recording industry, two separate strategies were developed to build the storage bit in last decade, introduction of perpendicular magnetic anisotropy (PMA) and adoption of ferrimagnetism/antiferromagnetism. Meanwhile, these properties significantly improve device performance, such as reducing spin-transfer torque energy consumption and decreasing signal-amplitude-loss. However, materials combining PMA and antiferromagnetism rather than transition-metal/rare-earth system were rarely developed. Here, we develop a new type of ferrimagnetic superlattice exhibiting PMA based on abundant Heusler alloy families. The superlattice is formed by [MnGa/Co2FeAl] unit with their magnetizations antiparallel aligned. The effective anisotropy (K(u)(eff)) over 6 Merg/cm(3) is obtained, and the SL can be easily built on various substrates with flexible lattice constants. The coercive force, saturation magnetization and K(u)(eff) of SLs are highly controllable by varying the thickness of MnGa and Co2FeAl layers. The SLs will supply a new choice for magnetic recording and spintronics memory application such as magnetic random access memory.

  15. Metallic Zinc Exhibits Optimal Biocompatibility for Bioabsorbable Endovascular Stents

    Science.gov (United States)

    Bowen, Patrick K.; Guillory, Roger J.; Shearier, Emily R.; Seitz, Jan-Marten; Drelich, Jaroslaw; Bocks, Martin; Zhao, Feng; Goldman, Jeremy

    2015-01-01

    Although corrosion resistant bare metal stents are considered generally effective, their permanent presence in a diseased artery is an increasingly recognized limitation due to the potential for long-term complications. We previously reported that metallic zinc exhibited an ideal biocorrosion rate within murine aortas, thus raising the possibility of zinc as a candidate base material for endovascular stenting applications. This study was undertaken to further assess the arterial biocompatibility of metallic zinc. Metallic zinc wires were punctured and advanced into the rat abdominal aorta lumen for up to 6.5 months. This study demonstrated that metallic zinc did not provoke responses that often contribute to restenosis. Low cell densities and neointimal tissue thickness, along with tissue regeneration within the corroding implant, point to optimal biocompatibility of corroding zinc. Furthermore, the lack of progression in neointimal tissue thickness over 6.5 months or the presence of smooth muscle cells near the zinc implant suggest that the products of zinc corrosion may suppress the activities of inflammatory and smooth muscle cells. PMID:26249616

  16. A thermochromic silver nanocluster exhibiting dual emission character

    Science.gov (United States)

    Xu, Qing-Qing; Dong, Xi-Yan; Huang, Ren-Wu; Li, Bo; Zang, Shuang-Quan; Mak, Thomas C. W.

    2015-01-01

    A Ag12(SCH2C10H7)6(CF3CO2)6(CH3CN)6 (1) nanocluster modified using naphthalen-2-yl-methanethiol was synthesized and structurally characterized by single crystal X-ray analysis. The targeted luminescent nanocluster displays dual emission with the property of reversible thermochromism spanning from red to bright yellow.A Ag12(SCH2C10H7)6(CF3CO2)6(CH3CN)6 (1) nanocluster modified using naphthalen-2-yl-methanethiol was synthesized and structurally characterized by single crystal X-ray analysis. The targeted luminescent nanocluster displays dual emission with the property of reversible thermochromism spanning from red to bright yellow. Electronic supplementary information (ESI) available: Experimental section and supporting Fig. S1-S6. CCDC 1004246. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4nr05122j

  17. Murine and human CFTR exhibit different sensitivities to CFTR potentiators

    OpenAIRE

    Cui, Guiying; McCarty, Nael A.

    2015-01-01

    Development of therapeutic molecules with clinical efficacy as modulators of defective CFTR includes efforts to identify potentiators that can overcome or repair the gating defect in mutant CFTR channels. This has taken a great leap forward with the identification of the potentiator VX-770, now available to patients as “Kalydeco.” Other small molecules with different chemical structure also are capable of potentiating the activity of either wild-type or mutant CFTR, suggesting that there are ...

  18. Photoreactive helical nanoaggregates exhibiting morphology transition on thermal reconstruction

    Science.gov (United States)

    Yamauchi, Mitsuaki; Ohba, Tomonori; Karatsu, Takashi; Yagai, Shiki

    2015-11-01

    The supramolecular design of photochromic molecules has produced various smart molecular assemblies that can switch their structures and/or functions in response to light stimuli. However, most of these assemblies require large structural changes of the photochromic molecules for an efficient conversion of assembled states, which often suppresses the photoreactivity within the self-assemblies. Here we report molecular assemblies, based on a photo-cross-linkable chromophoric dyad, in which a small amount of ultraviolet-generated photochemical product can guide the entire system into different assembly processes. In apolar solution, the intact dyad self-assembles into right-handed superhelical fibrils. On ultraviolet-irradiation of these fibrils, an effective photoreaction affords a sole photo-cross-linked product. When right-handed helical fibrils, containing a minor amount of the photoproduct, are thermally reconstructed, the intact molecule and the photoproduct undergo a co-assembly process that furnishes superhelical fibrils with different molecular packing structures. This molecular design principle should afford new paradigms for smart molecular assemblies.

  19. 7th IGRSM International Remote Sensing & GIS Conference and Exhibition

    Science.gov (United States)

    Shariff, Abdul Rashid Mohamed

    2014-06-01

    IGRSM This proceedings consists of the peer-reviewed papers from the 7th IGRSM International Conference and Exhibition on Remote Sensing & GIS (IGRSM 2014), which was held on 21-22 April 2014 at Berjaya Times Square Hotel, Kuala Lumpur, Malaysia. The conference, with the theme Geospatial Innovation for Nation Building was aimed at disseminating knowledge, and sharing expertise and experiences in geospatial sciences in all aspects of applications. It also aimed to build linkages between local and international professionals in this field with industries. Highlights of the conference included: Officiation by Y B Datuk Dr Abu Bakar bin Mohamad Diah, Deputy Minister of Minister of Science, Technology & Innovation Keynote presentations by: Associate Professor Dr Francis Harvey, Chair of the Geographic Information Science Commission at the International Geographical Union (IGU) and Director of U-Spatial, University of Minnesota, US: The Next Age of Discovery and a Future in a Post-GIS World. Professor Dr Naoshi Kondo, Bio-Sensing Engineering, University of Kyoto, Japan: Mobile Fruit Grading Machine for Precision Agriculture. Datuk Ir Hj Ahmad Jamalluddin bin Shaaban, Director-General, National Hydraulic Research Institute of Malaysia (NAHRIM), Malaysia: Remote Sensing & GIS in Climate Change Analyses. Oral and poster presentations from 69 speakers, from both Malaysia (35) and abroad (34), covering areas of water resources management, urban sprawl & social mobility, agriculture, land use/cover mapping, infrastructure planning, disaster management, technology trends, environmental monitoring, atmospheric/temperature monitoring, and space applications for the environment. Post-conference workshops on: Space Applications for Environment (SAFE), which was be organised by the Japan Aerospace Exploration Agency (JAXA) Global Positioning System (GPS) Receiver Evaluation Using GPS Simulation, which was be organised by the Science & Technology Research Institute for Defence

  20. Belongings: Oral History, Objects and an Online Exhibition

    Directory of Open Access Journals (Sweden)

    Janis Wilton

    2009-11-01

    Full Text Available The New South Wales Migration Heritage Centre was established in 1998. Since 2003 its physical presence has been located within Sydney’s Powerhouse Museum and it has had the strategic brief to record the memories of ageing migrants before their stories are lost. The Centre is, however, a museum without a collection; a heritage authority without heritage sites; a cultural institution whose main presence is in cyberspace. Among its high profile projects is one entitled Objects through time and another Belongings. Both focus on the ways in which objects can convey aspects of the migration experience. Belongings, the focus of this article, presents the remembered experiences of people who migrated to Australia after World War II, and seeks to highlight significant features of their experiences through asking them to share their memories and to nominate and talk about significant objects. As a project it grew out of movable heritage policy work within state government agencies, and its initiators – John Petersen, Kylie Winkworth and Meredith Walker – were central players in this development. It was also inspired by the National Quilt Register of the Pioneer Women’s Hut at Tumbarumba. With its object-centred approach and accompanying edited interview transcripts, Belongings provides a focus for exploring the messages and emphases that emerge when oral history interviews concerned with migration have the specific brief to ask about material culture and its significance. Belongings also enables an exploration of the layering of those messages that emerges when object captions are located back in the context of the oral history interviews from which they were extracted. As a virtual exhibition, Belongings also provides the opportunity to consider the challenges for museums (virtual and real when they need to condense the richness of migrant oral histories and life stories to captioned objects that can be put on display.

  1. Arabidopsis mutant bik1 exhibits strong resistance to Plasmodiophora brassicae

    Directory of Open Access Journals (Sweden)

    Tao Chen

    2016-09-01

    Full Text Available Botrytis-induced kinase1 (BIK1, a receptor-like cytoplasmic kinase, plays an important role in resistance against pathogens and insects in Arabidopsis thaliana. However, it remains unknown whether BIK1 functions against Plasmodiophora brassicae, an obligate biotrophic protist that attacks cruciferous plants and induces gall formation on roots. Here, we investigated the potential roles of receptors FLS2, BAK1 and BIK1 in the infection of P. brassicae cruciferous plants. Wild-type plants, fls2 and bak1 mutants showed typical symptom on roots, and the galls were filled with large quantities of resting spores, while bik1 mutant plants exhibited strong resistance to P. brassicae. Compared with that of the wild-type plants, the root hair and cortical infection rate of bik1 mutant were significantly reduced by about 40-50%. A considerable portion of bik1 roots failed to form typical galls. Even if some small galls were formed, they were filled with multinucleate secondary plasmodia. The bik1 plants accumulated less reactive oxygen species (ROS at infected roots than other mutants and wild-type plants. Exogenous salicylic acid (SA treatment alleviated the clubroot symptoms in wild-type plants, and the expression of the SA signaling marker gene PR1 was significantly increased in bik1. Both sid2 (salicylic acid induction-deficient 2 and npr1-1 (non-expresser of PR genes that regulate systemic acquired resistance (SAR mutants showed increased susceptibility to P. brassicae compared with wild-type plants. These results suggest that the resistance of bik1 to P. brassicae is possibly mediated by SA inducible mechanisms enhance the resistance to clubroot disease.

  2. Exhibiting evolution an essay upon the museum’s subjectivity

    Directory of Open Access Journals (Sweden)

    Pinna, Giovanni

    2009-12-01

    Full Text Available A museum is not only a physical place, a mere container of fragments of the cultural heritage. It is above all a unity of knowledge whose task of scientific research and analysis of the collections leads to an original interpretation of the world, to a specific culture, typical of each museum. Through its permanent exhibitions or any other means at its disposal, each museum conveys its cultural specificity to the visitor, a specificity which is different to that of other museums and does not intend to be objective. This paper aims to prove all the above by showing how, in different times and places, three important museums displayed three examples of evolution obtained form paleontology developing a totally subjective interpretation of the evolutionary process.

    El museo no es sólo un lugar físico, un simple contenedor de fragmentos del patrimonio cultural, es, sobretodo, una unidad de conocimiento cuya labor de investigación científica y análisis de las colecciones conduce a una interpretación del mundo totalmente original, a una cultura propia de cada museo. Utilizando las exposiciones permanentes, o cualquier otro medio a su disposición, cada museo comunica al público su especifidad cultural, que es diversa de la de otros museos y no quiere ser objetiva. Esto es cuanto el artículo pretende demostrar ilustrando cómo, en tiempos y lugares diferentes, tres grandes instituciones museísticas mostraron al público tres ejemplos de evolución obtenida de la paleontología desarrollando una interpretación totalmente subjetiva del proceso evolutivo.

  3. Ineffective oesophageal motility: Manometric subsets exhibit different symptom profiles

    Institute of Scientific and Technical Information of China (English)

    Horst Gunter Haack; Ross David Hansen; Allison Malcolm; John Edward Kellow

    2008-01-01

    AIM: To compare the demographic and clinical features of different manometric subsets of ineffective oesophageal motility (IOM; defined as ≥30% wet swallows with distal contractile amplitude <30 mmHg), and to determine whether the prevalence of gastro-oesophageal reflux differs between IOM subsets.METHODS: Clinical characteristics of manometric subsets were determined in 100 IOM patients (73 female, median age 58 years) and compared to those of 100 age-and gender-matched patient controls with oesophageal symptoms, but normal manometry. Supine oesophageal manometry was performed with an eight-channel DentSleeve water-perfused catheter, and an ambulatory pH study assessed gastrooesophageal reflux.RESULTS: Patients in the IOM subset featuring a majority of low-amplitude simultaneous contractions (LASC) experienced less heartburn (prevalence 26%), but more dysphagia (57%) than those in the IOM subset featuring low-amplitude propagated contractions (LAP; heartburn 70%, dysphagia 24%; both P≤0.01). LASC patients also experienced less heartburn and more dysphagia than patient controls (heartburn 68%, dysphagia 11%; both P<0.001). The prevalence of heartburn and dysphagia in IOM patients featuring a majority of non-transmitted sequences (NT) was 54% (P=0.04 vs LASC) and 36% (P<0.01 vs controls), respectively. No differences in age and gender distribution, chest pain prevalence, acid exposure time (AET) and symptom/reflux association existed between IOM subsets, or between subsets and controls.CONCLUSION: IOM patients with LASC exhibit a different symptom profile to those with LAP, but do not differ in gastro-oesophageal reflux prevalence. These findings raise the possibility of different pathophysiological mechanisms in IOM subsets, which warrants further investigation.

  4. 7 CFR Exhibit C to Subpart G of... - Implementation Procedures for the Farmland Protection Policy Act; Executive Order 11988...

    Science.gov (United States)

    2010-01-01

    ...; and Departmental Regulation 9500-3, Land Use Policy C Exhibit C to Subpart G of Part 1940 Agriculture..., Land Use Policy 1. Background. The Subtitle I of the Agriculture and Food Act of 1981, Pub. L. 97-98... practicable, elevate structures above the base flood level rather than filling in the land.” (d)...

  5. Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro.

    Science.gov (United States)

    Ghosh, Kaustabh; Thodeti, Charles K; Dudley, Andrew C; Mammoto, Akiko; Klagsbrun, Michael; Ingber, Donald E

    2008-08-12

    Tumor blood vessels exhibit abnormal structure and function that cause disturbed blood flow and high interstitial pressure, which impair delivery of anti-cancer agents. Past efforts to normalize the tumor vasculature have focused on inhibition of soluble angiogenic factors, such as VEGF; however, capillary endothelial (CE) cell growth and differentiation during angiogenesis are also influenced by mechanical forces conveyed by the extracellular matrix (ECM). Here, we explored the possibility that tumor CE cells form abnormal vessels because they lose their ability to sense and respond to these physical cues. These studies reveal that, in contrast to normal CE cells, tumor-derived CE cells fail to reorient their actin cytoskeleton when exposed to uniaxial cyclic strain, exhibit distinct shape sensitivity to variations in ECM elasticity, exert greater traction force, and display an enhanced ability to retract flexible ECM substrates and reorganize into tubular networks in vitro. These behaviors correlate with a constitutively high level of baseline activity of the small GTPase Rho and its downstream effector, Rho-associated kinase (ROCK). Moreover, decreasing Rho-mediated tension by using the ROCK inhibitor, Y27632, can reprogram the tumor CE cells so that they normalize their reorientation response to uniaxial cyclic strain and their ability to form tubular networks on ECM gels. Abnormal Rho-mediated sensing of mechanical cues in the tumor microenvironment may therefore contribute to the aberrant behaviors of tumor CE cells that result in the development of structural abnormalities in the cancer microvasculature.

  6. An Interactive Exhibition about Animal Skeletons: Did the Visitors Learn Any Zoology?

    Science.gov (United States)

    Tunnicliffe, Sue Dale; Laterveer-de Beer, Manon

    2002-01-01

    Explores museum visitors' understanding of skeleton exhibits and whether such exhibits increase their understanding of the zoology displayed. The exhibition under study focused on the diversity of vertebrae skeletons which were arranged according to the mode of locomotion. (DDR)

  7. 76 FR 44976 - Culturally Significant Objects Imported for Exhibition Determinations: “Heroic Africans...

    Science.gov (United States)

    2011-07-27

    ... Exhibition Determinations: ``Heroic Africans: Legendary Leaders, Iconic Sculptures'' SUMMARY: Notice is... objects to be included in the exhibition ``Heroic Africans: Legendary Leaders, Iconic Sculptures,'' imported from abroad for temporary exhibition within the United States, are of cultural significance....

  8. 75 FR 7649 - Culturally Significant Objects Imported for Exhibition Determinations: “Otto Dix”

    Science.gov (United States)

    2010-02-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Otto Dix'' SUMMARY: Notice is hereby... included in the exhibition ``Otto Dix,'' imported from abroad for temporary exhibition within the...

  9. Remote Manipulation for D&D Exhibiting Teleautonomy and Telecollaboration

    Energy Technology Data Exchange (ETDEWEB)

    Yule, Thomas J.; Colgate, J. Edward; Park, Young S.; Ewing, Thomas F.

    2002-06-01

    The purpose of the work is to enhance remote operations of robotic systems for D&D tasks by extending teleoperation with semi-autonomous functions. The work leverages the $1.2M dual-arm work platform (DAWP) developed with broad participation for the CP5 D&D, as well as 2,000 hr DAWP D&D operational experience. We propose to develop a reactive, agent-based control architecture well suited to unstructured and unpredictable environments, and robot control technology, which implements a virtual fixture that can be used to guide the application of tools with force-feedback control. Developed methodologies will be implemented using a structured light sensor and robot hand controller on the dual-arm system.

  10. Fibrillin microfibrils are reduced in skin exhibiting striae distensae.

    Science.gov (United States)

    Watson, R E; Parry, E J; Humphries, J D; Jones, C J; Polson, D W; Kielty, C M; Griffiths, C E

    1998-06-01

    Striae distensae (striae: stretch marks) are a common disfiguring condition associated with continuous and progressive stretching of the skin--as occurs during pregnancy. The pathogenesis of striae is unknown but probably relates to changes in those structures that provide skin with its tensile strength and elasticity. Such structures are components of the extracellular matrix, including fibrillin, elastin and collagens. Using a variety of histological techniques, we assessed the distribution of these extracellular matrix components in skin affected by striae. Pregnant women were assessed for the presence of striae, and punch biopsies were obtained from lesional striae and adjacent normal skin. Biopsies were processed for electron microscopy, light microscopy and immunohistochemistry. For histological examination, 7 microns frozen sections were stained so as to identify the elastic fibre network and glycosaminoglycans. Biopsies were also examined with a panel of polyclonal antibodies against collagens I and III, and fibrillin and elastin. Ultrastructural analysis revealed alterations in the appearance of skin affected by striae compared with that of normal skin in that the dermal matrix of striae was looser and more floccular. Light microscopy revealed an increase in glycosaminoglycan content in striae. Furthermore, the number of vertical fibrillin fibres subjacent to the dermal-epidermal junction (DEJ) and elastin fibres in the papillary dermis was significantly reduced in striae compared with normal skin. The orientation of elastin and fibrillin fibres in the deep dermis showed realignment in that the fibres ran parallel to the DEJ. However, no significant alterations were observed in any other extracellular matrix components. This study identifies a reorganization and diminution of the elastic fibre network of skin affected by striae. Continuous strain on the dermal extracellular matrix, as occurs during pregnancy, may remodel the elastic fibre network in

  11. 78 FR 48216 - Culturally Significant Objects Imported for Exhibition Determinations: “Balthus: Cats and Girls...

    Science.gov (United States)

    2013-08-07

    ... for Exhibition Determinations: ``Balthus: Cats and Girls--Paintings and Provocations'' SUMMARY: Notice..., I hereby determine that the objects to be included in the exhibition ``Balthus: Cats and...

  12. 77 FR 56698 - Culturally Significant Objects Imported for Exhibition Determinations: “Opera Nobile...

    Science.gov (United States)

    2012-09-13

    ... for Exhibition Determinations: ``Opera Nobile: Masterpieces From Ancient Italy'' SUMMARY: Notice is... objects to be included in the exhibition ``Opera Nobile: Masterpieces from Ancient Italy,'' imported...

  13. 75 FR 53731 - Culturally Significant Objects Imported for Exhibition Determinations: “Contemporary Argentine...

    Science.gov (United States)

    2010-09-01

    ... for Exhibition Determinations: ``Contemporary Argentine Masterworks'' SUMMARY: Notice is hereby given... hereby determine that the objects to be included in the exhibition ``Contemporary Argentine...

  14. A visitor study approach to INGV exhibition at Genova Science Festival 2011

    Science.gov (United States)

    Nave, R.; D'Addezio, G.; Carosi, A.

    2012-04-01

    The Istituto Nazionale di Geofisica e Vulcanologia (INGV) is one of the largest European scientific institution dealing with Earth Sciences research and seismic and volcanic surveillance. We organizes every year intense educational and outreach activities focalizing in particular on causes of earthquakes and volcanic eruptions and how to behave properly and deal with these events. This approach derived from the consciousness on the social role of a correct information on natural hazards and on the awareness that preparedness is the best way to live with and to mitigate natural hazard. The Genova Science Festival, held since 2003, is the most remarkable among the Italian Science Communication events and for or the 2011 edition, the INGV realized an exibition called COME E' PROFONDO IL MARE, la geofisica in acqua (HOW DEEP THE SEA IS, geophysics in water). The exhibition shows and explains the main geodinamic processes trough interactive exhibits and colorful panels exploring events as earthquakes, volcanic eruption and tsunami, their impact on our territory. In order to approach a visitor study related to this scientific educational path we elaborated questionnaires designed for students, for teacher and for general public. We have chosen this survey instrument for its advantage to get a wide variety of information and quantitative data. In developing the questionnaire three main aspects were taken in account: its shortness, clarity in the questions, and answers structure able to grade different indicator of visitor opinion and exhibition impact. That will also allow us to combine indicators scores during data elaboration phase. The questionnaire goes through all the section of the educational path, trying to have a feedback on the proposed layout and its efficacy. The Science Festival lasted 2 weeks and was visited by about 8000 people. During the event were handed out and recollected about 300 questionnaires that allows us to make a reliable assessment on the

  15. Ultralong Persistent Room Temperature Phosphorescence of Metal Coordination Polymers Exhibiting Reversible pH-Responsive Emission.

    Science.gov (United States)

    Yang, Yongsheng; Wang, Ke-Zhi; Yan, Dongpeng

    2016-06-22

    Ultra-long-persistent room temperature phosphorescence (RTP) materials have attracted much attention and present various applications in illumination, displays, and the bioimaging field; however, the persistent RTP is generally from the inorganic phosphor materials to date. Herein, we show that the metal coordination polymers (CPs) could be new types of emerging long-lived RTP materials for potential sensor applications. First, two kinds of Cd-based CPs, Cd(m-BDC)(H2O) (1) and Cd(m-BDC)(BIM) (2) (m-BDC = 1,3-benzenedicarboxylic acid; BIM = benzimidazole), were obtained through a hydrothermal process, and the samples were found to exhibit two-dimensional layered structures, which are stabilized by interlayer C-H···π interaction and π···π interaction, respectively. The CPs show unexpected second-time-scale ultra-long-persistent RTP after the removal of UV excitation, and this persistent emission can be detected easily on a time scale of 0-10 s. The CPs also feature a tunable luminescence decay lifetime by adjusting their coordination situation and packing fashion of ligands. Theoretical calculation further indicates that the introduction of the second ligand could highly influence the electronic structure and intermolecular electron transfer toward tailoring the RTP of the CP materials. Moreover, CP 2 exhibits well-defined pH- and temperature-dependent phosphorescence responses. Therefore, this work provides a facile way to develop new type of CPs with steady-state and dynamic tuning of the RTP properties from both experimental and theoretical perspectives, which have potential applications in the areas of displays, pH/temperature sensors, and phosphorescence logic gates. On account of suitable incorporation of inorganic and organic building blocks, it can be expected that the ultra-long-persistent RTP CPs can be extended to other similar systems due to the highly tunable structures and facile synthesis routes.

  16. Enhanced teleoperation exhibiting tele-autonomy and tele-collaboration.

    Energy Technology Data Exchange (ETDEWEB)

    Park, Y. S.; Ewing, T. F.; Yule, T. J.; Colgate, E.; Peshkin, M.

    2002-05-17

    This paper presents enhanced remote manipulation of tools for D&D tasks by extending teleoperation with teleautonomy and tele-collaboration. This work builds on a reactive, agent-based control architecture, which is well suited to unstructured and unpredictable environments, and cobot control technology, which implements a virtual fixture that can be used to guide the application of tools with passive force-feedback control. Developed methodologies are tested using simulation, and then planned to be implemented using a structured light sensor and cobot hand controller on a dual-arm system to measure the enhanced performance of key tool operations that are tedious and difficult to perform purely by teleoperation. This work significantly leverages some 2000 hours of operational experience gained during the D&D of the CP-5 reactor at ANL using a dual-arm remote manipulator system, as well as DOE's investment in the dual-arm system itself, which will serve as a test bed for the proposed investigations.

  17. Dermoscopy of Kaposi's sarcoma: areas exhibiting the multicoloured 'rainbow pattern'.

    Science.gov (United States)

    Hu, S C-S; Ke, C-L K; Lee, C-H; Wu, C-S; Chen, G-S; Cheng, S-T

    2009-10-01

    Kaposi's sarcoma is a vascular tumour characterized by a proliferation of spindle cells and endothelial cells to form closely arranged slit-like vascular spaces. Currently, the definitive diagnosis of Kaposi's sarcoma relies on histology. The dermoscopic features of Kaposi's sarcoma are not clearly defined in the scientific literature. We seek to evaluate the dermoscopic features of Kaposi's sarcoma and compare them with other vascular tumours. One hundred forty-one lesions from seven patients with histologically proven Kaposi's sarcoma were evaluated using polarized light dermoscopy for the presence of various dermoscopic features. Twenty patients with other vascular tumours were also examined. Dermoscopic examination revealed bluish-reddish coloration (84% of lesions), multicoloured areas showing various colours of the rainbow spectrum (36%), scaly surface (29%), and small brown globules (15%). The 'rainbow pattern' was found in six out of seven patients with Kaposi's sarcoma and was not observed in other vascular tumours. In addition, there was an absence of dermoscopic features specific for other vascular and non-vascular skin tumours, such as well-defined lacunae or structured vascular pattern, in most of the Kaposi's sarcoma lesions. The most frequent dermoscopic patterns in Kaposi's sarcoma were found to be bluish-reddish coloration, the 'rainbow pattern', and scaly surface. The rainbow pattern is a dermoscopic feature which has not been previously described. We propose that dermoscopy, as an adjunct to clinical examination, may enhance accuracy in the preoperative diagnosis of Kaposi's sarcoma.

  18. Expressive writing difficulties in children described as exhibiting ADHD symptoms.

    Science.gov (United States)

    Re, Anna Maria; Pedron, Martina; Cornoldi, Cesare

    2007-01-01

    Three groups of children of different ages who were considered by their teachers as showing symptoms of attention-deficit/hyperactivity disorder (ADHD) and matched controls were tested in a series of expressive writing tasks, derived from a standardized writing test. In the first study, 24 sixth- and seventh-grade children with ADHD symptoms wrote a description of an image. The ADHD group's expressive writing was worse than that of the control group and associated with a higher number of errors, mainly concerning accents and geminates. The second study showed the generality of the effect by testing younger groups of children with ADHD symptoms and controls with another description task where a verbal description was substituted for the picture stimulus. The third study extended the previous observations with another type of writing task, the request of writing a narrative text. In all the three studies, children with ADHD symptoms scored lower than controls on four qualitative parameters (adequacy, structure, grammar, and lexicon), produced shorter texts, and made more errors. These studies show that children with ADHD symptoms have school difficulties also in writing-both in spelling and expression-and that these difficulties are extended to different tasks and ages.

  19. Ant workers exhibit specialization and memory during raft formation

    Science.gov (United States)

    Avril, Amaury; Purcell, Jessica; Chapuisat, Michel

    2016-06-01

    By working together, social insects achieve tasks that are beyond the reach of single individuals. A striking example of collective behaviour is self-assembly, a process in which individuals link their bodies together to form structures such as chains, ladders, walls or rafts. To get insight into how individual behavioural variation affects the formation of self-assemblages, we investigated the presence of task specialization and the role of past experience in the construction of ant rafts. We subjected groups of Formica selysi workers to two consecutive floods and monitored the position of individuals in rafts. Workers showed specialization in their positions when rafting, with the same individuals consistently occupying the top, middle, base or side position in the raft. The presence of brood modified workers' position and raft shape. Surprisingly, workers' experience in the first rafting trial with brood influenced their behaviour and raft shape in the subsequent trial without brood. Overall, this study sheds light on the importance of workers' specialization and memory in the formation of self-assemblages.

  20. Environment construction and bottleneck breakthrough in the improvement of wisdom exhibition

    Science.gov (United States)

    Zhang, Jiankang

    2017-08-01

    Wisdom exhibition is an inexorable trend in convention and exhibition industry in China. Information technology must be utilized by exhibition industry to achieve intelligent application and wisdom management, breaking the limitation of time as well as space, which raise the quality of exhibition service and level of operation to a totally new standard. Accordingly, exhibition industry should optimize mobile internet, a fundamental technology platform, during the advancing process of wisdom exhibition and consummate the combination among three plates including wisdom connection of information, wisdom exhibition environment and wisdom application of technology. Besides, the industry should realize the wisdom of external environment including wisdom of exhibition city, exhibition place, exhibition resource deal etc and break through bottle-neck in construction of wisdom exhibition industry, which includes construction of big data center, development of Mobile Internet application platform, promotion of information construction, innovative design of application scenarios.

  1. Behçet's syndrome patients exhibit specific microbiome signature.

    Science.gov (United States)

    Consolandi, Clarissa; Turroni, Silvia; Emmi, Giacomo; Severgnini, Marco; Fiori, Jessica; Peano, Clelia; Biagi, Elena; Grassi, Alessia; Rampelli, Simone; Silvestri, Elena; Centanni, Manuela; Cianchi, Fabio; Gotti, Roberto; Emmi, Lorenzo; Brigidi, Patrizia; Bizzaro, Nicola; De Bellis, Gianluca; Prisco, Domenico; Candela, Marco; D'Elios, Mario M

    2015-04-01

    Behçet syndrome is a systemic inflammatory condition characterized by muco-cutaneous and ocular manifestations, with central nervous system, vascular and/or gastro-intestinal involvement. The association of microbiota with Behçet syndrome has not been shown yet. Our work was aimed to compare the gut microbiota structure and the profiles of short-chain fatty acids production in Behçet syndrome patients and healthy control relatives. Here, we compared the fecal microbiota of 22 patients with Behçet syndrome and that of 16 healthy co-habiting controls, sharing the same diet and lifestyle by pyrosequencing of the V3-V4 hypervariable regions of the 16 rDNA gene and biochemical analyses. Our analyses showed significant differences in gut microbiota between Behçet patients and healthy cohabitants. In particular we found that Behçet's patients were significantly depleted in the genera Roseburia and Subdoligranulum. Roseburia showed a relative abundance value of 10.45±6.01% in healthy relatives and 4.97±5.09% in Behçet's patients, and Subdoligranulum, which reached a relative abundance of 3.28±2.20% in healthy controls, was only at 1.93±1.75% of abundance in Behçet's patients. Here we report, for the first time, that a peculiar dysbiosis of the gut microbiota is present in patients with Behçet syndrome and this corresponds to specific changes in microbiome profile. A significant decrease of butyrate production (P=0.0033) in Behçet's patients was demonstrated. Butyrate is able to promote differentiation of T-regulatory cells, and consequently the results obtained prompt us to speculate that a defect of butyrate production might lead to both reduced T-reg responses and activation of immuno-pathological T-effector responses. Altogether, our results indicate that both a peculiar dysbiosis of the gut microbiota and a significant decrease of butyrate production are present in patients with Behçet syndrome. Published by Elsevier B.V.

  2. 17 CFR 260.7a-29 - Incorporation of exhibits as such.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Incorporation of exhibits as... Incorporation of exhibits as such. (a) Any exhibit or part thereof previously or concurrently filed with the...) and § 229.10(d) of this chapter, be incorporated by reference as an exhibit to any...

  3. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Johan Zoffany RA: Society...

    Science.gov (United States)

    2011-10-13

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Johan Zoffany RA: Society Observed... determine that the objects to be included in the exhibition ``Johan Zoffany RA: Society Observed,'' imported... that the exhibition or display of the exhibit objects at the Yale Center for British Art, New...

  4. 78 FR 45285 - Culturally Significant Objects Imported for Exhibition Determinations: “Egypt's Mysterious Book...

    Science.gov (United States)

    2013-07-26

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Egypt's Mysterious Book of the..., 2003), I hereby determine that the objects to be included in the exhibition ``Egypt's Mysterious Book... custodians. I also determine that the exhibition or display of the exhibit objects at The Walters Art...

  5. YINCHUAN INTERNATIONAL CONFERENCE AND EXHIBITION CENTER%银川国际会展中心

    Institute of Scientific and Technical Information of China (English)

    叶俊; 陈玲

    2012-01-01

    本文通过银川国际会展中心的设计,从城市、功能和表现地域文化三方面讨论中小型会展建筑的设计问题,提出在尊重城市总体规划的前提下,通过灵活的空间布局满足多变的功能使用需求,并从形式和结构单元结合表现地域文化方面做了探讨和尝试。%Through the introduction of Yinchuan International Conference and Exhibition Center design, our design focuses on the general problems of medium size conference and exhibition center design in three aspects: urban, function and regional culture expression. Respecting the urban planning foremost, we propose to satisfy various functional demand by the flexibility of layout, meanwhile try to search form-structure way of regional culture expression.

  6. Recombinant dioscorins of the yam storage protein expressed in Escherichia coli exhibit antioxidant and immunomodulatory activities.

    Science.gov (United States)

    Jheng, Yi-Jyun; Tsai, Wei-Yi; Chen, Kuo-Hsuan; Lin, Kuo-Wei; Chyan, Chia-Lin; Yang, Ching-Chi; Lin, Kuo-Chih

    2012-09-01

    Dioscorins, the major storage proteins in yam tubers, exhibit biochemical and immunomodulatroy activities. To investigate the potential application of dioscorins in biomedical research, we expressed the dioscorin genes Dj-dioA3 and Dp-dioA2 from Dioscorea japonica and Dioscorea pseudojaponica, respectively, in E. coli and routinely obtained approximately 15 mg proteins per liter Escherichia coli culture (mg/L) to 30 mg/L of rDj-dioscorinA3 and 4 to 8 mg/L of rDp-dioscorinA2. Western blot analyses revealed that both recombinant dioscorins contained epitopes with similar antigenicities to those of the native dioscorins. Results from dithiothreitol (DTT) treatment followed by monobromobimane (mBBr) staining showed that both recombinant dioscorins, like the native dioscorins, contain an intramolecular disulfide bond between Cys(28) and Cys(187) residues. Circular dichroism spectroscopy findings indicated that the secondary structural contents of the recombinant dioscorins showed high similarity to those of their corresponding native dioscorins. Both recombinant dioscorins, like the native dioscorins, exhibited 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and Toll-like receptor 4 signaling activities, and stimulated the phagocytosis of E. coli by macrophage. Overall, our results indicated that substantial amounts of recombinant dioscorins can be purified easily from E. coli and that these recombinant dioscorins are appropriate for application in future investigations of the biomedical functions of dioscorins.

  7. The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease.

    Science.gov (United States)

    Sidhaye, Jaydeep; Pinto, Clyde Savio; Dharap, Shweta; Jacob, Tressa; Bhargava, Shobha; Sonawane, Mahendra

    2016-11-01

    Microvillus inclusion disease (MVID) is a life-threatening enteropathy characterised by malabsorption and incapacitating fluid loss due to chronic diarrhoea. Histological analysis has revealed that enterocytes in MVID patients exhibit reduction of microvilli, presence of microvillus inclusion bodies and intestinal villus atrophy, whereas genetic linkage analysis has identified mutations in myosin Vb gene as the main cause of MVID. In order to understand the cellular basis of MVID and the associated formation of inclusion bodies, an animal model that develops ex utero and is tractable genetically as well as by microscopy would be highly useful. Here we report that the intestine of the zebrafish goosepimples (gsp)/myosin Vb (myoVb) mutant shows severe reduction in intestinal folds - structures similar to mammalian villi. The loss of folds is further correlated with changes in the shape of enterocytes. In striking similarity with MVID patients, zebrafish gsp/myoVb mutant larvae exhibit microvillus atrophy, microvillus inclusions and accumulation of secretory material in enterocytes. We propose that the zebrafish gsp/myoVb mutant is a valuable model to study the pathophysiology of MVID. Furthermore, owing to the advantages of zebrafish in screening libraries of small molecules, the gsp mutant will be an ideal tool to identify compounds having therapeutic value against MVID.

  8. C1galt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes.

    Science.gov (United States)

    Kudo, Takashi; Sato, Takashi; Hagiwara, Kozue; Kozuma, Yukinori; Yamaguchi, Takashi; Ikehara, Yuzuru; Hamada, Michito; Matsumoto, Ken; Ema, Masatsugu; Murata, Soichiro; Ohkohchi, Nobuhiro; Narimatsu, Hisashi; Takahashi, Satoru

    2013-08-29

    C1galt1 is essential for synthesis of the core 1 structure of mucin-type O-glycans. To clarify the physiological role of O-glycans in adult hematopoiesis, we exploited the interferon-inducible Mx1-Cre transgene to conditionally ablate the C1galt(flox) allele (Mx1-C1). Mx1-C1 mice exhibit severe thrombocytopenia, giant platelets, and prolonged bleeding times. Both the number and DNA ploidy of megakaryocytes in Mx1-C1 bone marrow were similar to those in wild-type (WT) mice. However, there were few proplatelets in Mx1-C1 primary megakaryocytes. Conversely, bone marrow transplanted from Mx1-C1 to WT and splenectomized Mx1-C1 mice gave rise to observations similar to those described above. The expression of GPIbα messenger RNA was unchanged in Mx1-C1 bone marrow, whereas flow cytometric and western blot analyses using megakaryocytes and platelets revealed that the expression of GPIbα protein was significantly reduced in Mx1-C1 mice. Moreover, circulating Mx1-C1 platelets exhibited an increase in the number of microtubule coils, despite normal levels of α- and β-tubulin. Our observations suggest that O-glycan is required for terminal megakaryocyte differentiation and platelet production and that the decrease in GPIbα in cells lacking O-glycan might be caused by increased proteolysis.

  9. Fish and phytoplankton exhibit contrasting temporal species abundance patterns in a dynamic north temperate lake.

    Directory of Open Access Journals (Sweden)

    Gretchen J A Hansen

    Full Text Available Temporal patterns of species abundance, although less well-studied than spatial patterns, provide valuable insight to the processes governing community assembly. We compared temporal abundance distributions of two communities, phytoplankton and fish, in a north temperate lake. We used both 17 years of observed relative abundance data as well as resampled data from Monte Carlo simulations to account for the possible effects of non-detection of rare species. Similar to what has been found in other communities, phytoplankton and fish species that appeared more frequently were generally more abundant than rare species. However, neither community exhibited two distinct groups of "core" (common occurrence and high abundance and "occasional" (rare occurrence and low abundance species. Both observed and resampled data show that the phytoplankton community was dominated by occasional species appearing in only one year that exhibited large variation in their abundances, while the fish community was dominated by core species occurring in all 17 years at high abundances. We hypothesize that the life-history traits that enable phytoplankton to persist in highly dynamic environments may result in communities dominated by occasional species capable of reaching high abundances when conditions allow. Conversely, longer turnover times and broad environmental tolerances of fish may result in communities dominated by core species structured primarily by competitive interactions.

  10. The Construction of an exhibition within architecture culture deconstructivist architecture, The Museum of Modern Art, 1988

    OpenAIRE

    2016-01-01

    The 1988 Deconstructivist Architecture exhibition at the Museum of Modern Art, New York, curated by Philip Johnson and Mark Wigley, was a minor exhibition that forced architecture to change directions. The tenweek exhibition showed ten projects by seven architects, staged in three galleries. Polemics surrounded the exhibition. These polemics, coupled with Johnson’s reputation and the extreme formal reduction of the show, fueled interest within the press. The exhibition recei...

  11. Impressive electromagnetic shielding effects exhibited by highly ordered, micrometer thick polyaniline films

    Science.gov (United States)

    Mohan, Ranjini R.; Varma, Sreekanth J.; Sankaran, Jayalekshmi

    2016-04-01

    The present work highlights the remarkably high shielding effectiveness of about 68 dB, exhibited by highly ordered and doped polyaniline films, in the microwave frequency range 4-12 GHz, obtained by self-stabilized dispersion polymerization as the synthesis route. The observed shielding effectiveness is found to depend quite sensitively on the electrical conducting properties, which are predominantly controlled by the nature and concentration of the dopants. The structural and morphological characterization of the films using XRD and TEM techniques reveals surprisingly high extent of crystallinity, which contributes significantly towards enhancing the electrical conductivity of the films. Most of the available reports on the microwave response of conducting polymer film samples deal with much thicker films, compared to the micrometer thick films of the present studies. The shielding effectiveness of acid doped, micrometer thick polyaniline films reported in the present work far exceeds most of the previously reported values and meets the commercial requirements.

  12. Dual-Use Space Technology Transfer Conference and Exhibition. Volume 2

    Science.gov (United States)

    Krishen, Kumar (Compiler)

    1994-01-01

    This is the second volume of papers presented at the Dual-Use Space Technology Transfer Conference and Exhibition held at the Johnson Space Center February 1-3, 1994. Possible technology transfers covered during the conference were in the areas of information access; innovative microwave and optical applications; materials and structures; marketing and barriers; intelligent systems; human factors and habitation; communications and data systems; business process and technology transfer; software engineering; biotechnology and advanced bioinstrumentation; communications signal processing and analysis; medical care; applications derived from control center data systems; human performance evaluation; technology transfer methods; mathematics, modeling, and simulation; propulsion; software analysis and decision tools; systems/processes in human support technology; networks, control centers, and distributed systems; power; rapid development; perception and vision technologies; integrated vehicle health management; automation technologies; advanced avionics; and robotics technologies.

  13. Towards Image Documentation of Grave Coverings and Epitaphs for Exhibition Purposes

    Science.gov (United States)

    Pomaska, G.; Dementiev, N.

    2015-08-01

    Epitaphs and memorials as immovable items in sacred spaces provide with their inscriptions valuable documents of history. Today not only photography or photos are suitable as presentation material for cultural assets in museums. Computer vision and photogrammetry provide methods for recording, 3D modelling, rendering under artificial light conditions as well as further options for analysis and investigation of artistry. For exhibition purposes epitaphs have been recorded by the structure from motion method. A comparison of different kinds of SFM software distributions could be worked out. The suitability of open source software in the mesh processing chain from modelling up to displaying on computer monitors should be answered. Raspberry Pi, a computer in SoC technology works as a media server under Linux applying Python scripts. Will the little computer meet the requirements for a museum and is the handling comfortable enough for staff and visitors? This contribution reports about the case study.

  14. G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold

    DEFF Research Database (Denmark)

    Marusic, Maja; Veedu, Rakesh N; Wengel, Jesper

    2013-01-01

    The formation of a single G-quadruplex structure adopted by a promising 25 nt G-rich vascular endothelial growth factor aptamer in a K(+) rich environment was facilitated by locked nucleic acid modifications. An unprecedented all parallel-stranded monomeric G-quadruplex with three G-quartet planes...... residues contribute to thermal stabilization of the adopted structure and formation of structurally pre-organized intermediates that facilitate folding into a single G-quadruplex. Understanding the impact of chemical modifications on folding, thermal stability and structural polymorphism of G...... exhibits several unique structural features. Five consecutive guanine residues are all involved in G-quartet formation and occupy positions in adjacent DNA strands, which are bridged with a no-residue propeller-type loop. A two-residue D-shaped loop facilitates inclusion of an isolated guanine residue...

  15. Testing the impact on natural risks' awareness of visual communication through an exhibition

    Science.gov (United States)

    Charrière, Marie; Bogaard, Thom; Junier, Sandra; Malet, Jean-Philippe; Mostert, Erik

    2014-05-01

    The need to communicate about natural disasters in order to improve the awareness of communities at risk is not a matter for debate anymore. However, communication can be implemented using different media and tools, and their effectiveness may be difficult to grasp. Current research on the topic is usually focused on assessing whether communication practices meet users' needs, whereas impact assessment is mostly left out. It can be explained by difficulties arising from (1) the definition of the impact to measure, i.e. awareness, and the appropriate indicators to measure it and its variations, and (2) the implementation of a research design that allows assessing these impacts without bias. This research aims at both developing a methodology to measure risk awareness and to use it for testing the effectiveness of visual communication. The testing was conducted in the Ubaye Valley in France, an alpine area affected by multiple hazards, from December 2013 to mid-February 2014. The setting consisted of an exhibition in the public library of the main town, Barcelonnette. The main natural hazards of the study case (i.e. landslides, avalanches, flooding, debris flows and earthquakes), as well as structural and non-structural measures were presented to the general public using local examples of hazards events and mitigation. Various visualization tools were used: videos, Google earth map, interactive timeline, objects, mock-ups, technical devices as well as posters with pictures, drawings and graphs. In order to assess the effects of the exhibition on risk awareness, several groups of children and adults were submitted to a research design, consisting of 1) a pre-test, 2) the visit of the exhibition and 3) a post-test similar to the pre-test. Close-ended questions addressed the awareness indicators according to the literature, i.e. worry level, previous experiences with natural hazards events, exposure to awareness raising, ability to mitigate/respond/prepare, attitude to

  16. Microbial eukaryote plankton communities of high-mountain lakes from three continents exhibit strong biogeographic patterns.

    Science.gov (United States)

    Filker, Sabine; Sommaruga, Ruben; Vila, Irma; Stoeck, Thorsten

    2016-05-01

    Microbial eukaryotes hold a key role in aquatic ecosystem functioning. Yet, their diversity in freshwater lakes, particularly in high-mountain lakes, is relatively unknown compared with the marine environment. Low nutrient availability, low water temperature and high ultraviolet radiation make most high-mountain lakes extremely challenging habitats for life and require specific molecular and physiological adaptations. We therefore expected that these ecosystems support a plankton diversity that differs notably from other freshwater lakes. In addition, we hypothesized that the communities under study exhibit geographic structuring. Our rationale was that geographic dispersal of small-sized eukaryotes in high-mountain lakes over continental distances seems difficult. We analysed hypervariable V4 fragments of the SSU rRNA gene to compare the genetic microbial eukaryote diversity in high-mountain lakes located in the European Alps, the Chilean Altiplano and the Ethiopian Bale Mountains. Microbial eukaryotes were not globally distributed corroborating patterns found for bacteria, multicellular animals and plants. Instead, the plankton community composition emerged as a highly specific fingerprint of a geographic region even on higher taxonomic levels. The intraregional heterogeneity of the investigated lakes was mirrored in shifts in microbial eukaryote community structure, which, however, was much less pronounced compared with interregional beta-diversity. Statistical analyses revealed that on a regional scale, environmental factors are strong predictors for plankton community structures in high-mountain lakes. While on long-distance scales (>10 000 km), isolation by distance is the most plausible scenario, on intermediate scales (up to 6000 km), both contemporary environmental factors and historical contingencies interact to shift plankton community structures.

  17. Polymer nanocomposite hydrogels exhibiting both dynamic restructuring and unusual adhesive properties.

    Science.gov (United States)

    Wang, Mian; Yuan, Du; Fan, Xiaoshan; Sahoo, Nanda Gopal; He, Chaobin

    2013-06-11

    Polymer nanocomposite (NC) hydrogels exhibiting both dynamic restructuring and unusual adhesive properties in wet and dry states have been prepared in an efficient and straightforward way via free radical polymerization of poly(ethylene glycol) methyl ether acrylate (PEG) in the presence of silane-modified sodium montmorillonite (NaMMT). The dynamic restructuring of the NC gel has been demonstrated by almost instant recovery of mechanical properties, such as storage modulus, loss modulus, and damping tan δ (at 0.025 strain) by 60-110% after being stressed to the point of gel failure. Furthermore, the dry NC gel showed exceptional thermal and mechanical stability during a heating and cooling cycle between 25 and 110 °C, with only slightly decreases followed by at least 30% increases in both moduli, while tan δ remained nearly unchanged. The NC gel in dry state could repeatedly adhere to various surfaces such as steel, glass, plastic, etc., and detach from the surface without being broken and leaving little contamination behind. This unique adhesive characteristic was characterized by high storage modulus, loss modulus (kPa), and tan δ (>0.6) corresponding to high cohesive, adhesive, and tacking properties of pressure-sensitive adhesives (PSAs). Finally, a reversible network structure formed by PEO interpenetrating within 3-dimentional (3-D) silica network was proposed to be responsible for the dynamic restructuring and the unique adhesive behaviors observed in the NC gel, and the 3-D network structure was investigated by XRD, FTIR, and DSC measurements. For this 3-D network structure, we suggest that the flexibility of PEO could allow PEO side chains to contact with various surfaces by either PEO segments or methoxy end groups via weak physical interactions, such as van der Waals interactions or hydrogen bonding, whereas the reversible network structure contributes to the recovery of strength and shape after the gel failure.

  18. New strategy to construct single-ion magnets: a unique Dy@Zn₆ cluster exhibiting slow magnetic relaxation.

    Science.gov (United States)

    Xiong, Gang; Qin, Xiang-Yang; Shi, Peng-Fei; Hou, Yin-Ling; Cui, Jian-Zhong; Zhao, Bin

    2014-04-25

    Two unique heptanuclear clusters Ln@Zn6 (Ln = Dy (1), Er (2)) were structurally and magnetically characterized. Each Dy(3+)/Er(3+) is located in a nona-coordinate D(3h) coordination environment, and is encapsulated in a diamagnetic Zn6 cage. Compound 1 exhibits single-ion magnetic behavior, and is the first example of a single-ion magnet (SIM) constructed through embedding one magnetic anisotropic metal ion into a diamagnetic cage.

  19. DELPHI Exhibition

    CERN Multimedia

    2000-01-01

    DELPHI (Detector for Lepton, Photon and Hadron Identification) is a detector for e+e- physics, with special emphasis on powerful particle identification, three-dimensional information, high granularity and precise vertex determination. It is installed at LEP (Large Electron and Positron collider) at CERN where it has operated since 1989. The present collaboration consists of about 550 physicists from 56 participating universities and institutes in 22 countries.

  20. Cytochrome c1 exhibits two binding sites for cytochrome c in plants.

    Science.gov (United States)

    Moreno-Beltrán, Blas; Díaz-Quintana, Antonio; González-Arzola, Katiuska; Velázquez-Campoy, Adrián; De la Rosa, Miguel A; Díaz-Moreno, Irene

    2014-10-01

    In plants, channeling of cytochrome c molecules between complexes III and IV has been purported to shuttle electrons within the supercomplexes instead of carrying electrons by random diffusion across the intermembrane bulk phase. However, the mode plant cytochrome c behaves inside a supercomplex such as the respirasome, formed by complexes I, III and IV, remains obscure from a structural point of view. Here, we report ab-initio Brownian dynamics calculations and nuclear magnetic resonance-driven docking computations showing two binding sites for plant cytochrome c at the head soluble domain of plant cytochrome c1, namely a non-productive (or distal) site with a long heme-to-heme distance and a functional (or proximal) site with the two heme groups close enough as to allow electron transfer. As inferred from isothermal titration calorimetry experiments, the two binding sites exhibit different equilibrium dissociation constants, for both reduced and oxidized species, that are all within the micromolar range, thus revealing the transient nature of such a respiratory complex. Although the docking of cytochrome c at the distal site occurs at the interface between cytochrome c1 and the Rieske subunit, it is fully compatible with the complex III structure. In our model, the extra distal site in complex III could indeed facilitate the functional cytochrome c channeling towards complex IV by building a "floating boat bridge" of cytochrome c molecules (between complexes III and IV) in plant respirasome.

  1. Tricarboxylate-based Gd(III) coordination polymers exhibiting large magnetocaloric effects.

    Science.gov (United States)

    Liu, Sui-Jun; Cao, Chen; Xie, Chen-Chao; Zheng, Teng-Fei; Tong, Xiao-Lan; Liao, Jin-Sheng; Chen, Jing-Lin; Wen, He-Rui; Chang, Ze; Bu, Xian-He

    2016-05-31

    Two Gd(III) coordination polymers with the formula [Gd(cit)(H2O)]∞ () and [Gd(nta)(H2O)2]∞ () (H4cit = citric acid, H3nta = nitrilotriacetic acid) have been successfully prepared under hydrothermal conditions. Complex exhibits a three-dimensional (3D) structure based on carboxylate-bridged layers, while complex is a double-layer structure containing eight-coordinated Gd(III). Magnetic investigations reveal that weak antiferromagnetic couplings between adjacent Gd(III) ions in both and with different Weiss values result in large cryogenic magnetocaloric effects. It is notable that the maximum entropy changes (-ΔS) of and reach 31.3 J kg(-1) K(-1) and 32.2 J kg(-1) K(-1) at 2 K for a moderate field change (ΔH = 3 T), and a remarkable -ΔS (41.5 J kg(-1) K(-1) for and 42.0 J kg(-1) K(-1) for ) could be obtained for ΔH = 7 T.

  2. Formyl Peptide Receptors from Immune and Vomeronasal System Exhibit Distinct Agonist Properties*

    Science.gov (United States)

    Bufe, Bernd; Schumann, Timo; Zufall, Frank

    2012-01-01

    The formyl peptide receptor (Fpr) family is well known for its contribution to immune defense against pathogens in human and rodent leukocytes. Recently, several structurally related members of these receptors were discovered in sensory neurons of the mouse vomeronasal organ (VNO), key detectors of pheromones and related semiochemicals. Although the biological role of vomeronasal Fprs is not yet clear, the known contribution of other Fprs to host immune defense suggested that they could contribute to vomeronasal pathogen sensing. Precise knowledge about the agonist properties of mouse Fprs is required to determine their function. We expressed all seven mouse and three human Fprs using an in vitro system and tested their activation with 32 selected compounds by conducting high throughput calcium measurements. We found an intriguing functional conservation between human and mouse immune Fprs that is most likely a consequence of closely similar biological constraints. By contrast, our data suggest a neofunctionalization of the vomeronasal Fprs. We show that the vomeronasal receptor mFpr-rs1 can be activated robustly by W-peptide and structural derivatives but not by other typical ligands of immune Fprs. mFpr-rs1 exhibits a stereo-selective preference for peptides containing d-amino acids. The same peptide motifs are contained in pathogenic microorganisms. Thus, the ligand profile of mFpr-rs1 is consistent with a role in vomeronasal pathogen sensing. PMID:22859307

  3. Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias.

    Science.gov (United States)

    Park, David S; Cerrone, Marina; Morley, Gregory; Vasquez, Carolina; Fowler, Steven; Liu, Nian; Bernstein, Scott A; Liu, Fang-Yu; Zhang, Jie; Rogers, Christopher S; Priori, Silvia G; Chinitz, Larry A; Fishman, Glenn I

    2015-01-01

    SCN5A encodes the α subunit of the major cardiac sodium channel Na(V)1.5. Mutations in SCN5A are associated with conduction disease and ventricular fibrillation (VF); however, the mechanisms that link loss of sodium channel function to arrhythmic instability remain unresolved. Here, we generated a large-animal model of a human cardiac sodium channelopathy in pigs, which have cardiac structure and function similar to humans, to better define the arrhythmic substrate. We introduced a nonsense mutation originally identified in a child with Brugada syndrome into the orthologous position (E558X) in the pig SCN5A gene. SCN5A(E558X/+) pigs exhibited conduction abnormalities in the absence of cardiac structural defects. Sudden cardiac death was not observed in young pigs; however, Langendorff-perfused SCN5A(E558X/+) hearts had an increased propensity for pacing-induced or spontaneous VF initiated by short-coupled ventricular premature beats. Optical mapping during VF showed that activity often began as an organized focal source or broad wavefront on the right ventricular (RV) free wall. Together, the results from this study demonstrate that the SCN5A(E558X/+) pig model accurately phenocopies many aspects of human cardiac sodium channelopathy, including conduction slowing and increased susceptibility to ventricular arrhythmias.

  4. Laminin α4 deficient mice exhibit decreased capacity for adipose tissue expansion and weight gain.

    Directory of Open Access Journals (Sweden)

    Marcella K Vaicik

    Full Text Available Obesity is a global epidemic that contributes to the increasing medical burdens related to type 2 diabetes, cardiovascular disease and cancer. A better understanding of the mechanisms regulating adipose tissue expansion could lead to therapeutics that eliminate or reduce obesity-associated morbidity and mortality. The extracellular matrix (ECM has been shown to regulate the development and function of numerous tissues and organs. However, there is little understanding of its function in adipose tissue. In this manuscript we describe the role of laminin α4, a specialized ECM protein surrounding adipocytes, on weight gain and adipose tissue function. Adipose tissue accumulation, lipogenesis, and structure were examined in mice with a null mutation of the laminin α4 gene (Lama4-/- and compared to wild-type (Lama4+/+ control animals. Lama4-/- mice exhibited reduced weight gain in response to both age and high fat diet. Interestingly, the mice had decreased adipose tissue mass and altered lipogenesis in a depot-specific manner. In particular, epididymal adipose tissue mass was specifically decreased in knock-out mice, and there was also a defect in lipogenesis in this depot as well. In contrast, no such differences were observed in subcutaneous adipose tissue at 14 weeks. The results suggest that laminin α4 influences adipose tissue structure and function in a depot-specific manner. Alterations in laminin composition offers insight into the roll the ECM potentially plays in modulating cellular behavior in adipose tissue expansion.

  5. Laminin α4 deficient mice exhibit decreased capacity for adipose tissue expansion and weight gain.

    Science.gov (United States)

    Vaicik, Marcella K; Thyboll Kortesmaa, Jill; Movérare-Skrtic, Sofia; Kortesmaa, Jarkko; Soininen, Raija; Bergström, Göran; Ohlsson, Claes; Chong, Li Yen; Rozell, Björn; Emont, Margo; Cohen, Ronald N; Brey, Eric M; Tryggvason, Karl

    2014-01-01

    Obesity is a global epidemic that contributes to the increasing medical burdens related to type 2 diabetes, cardiovascular disease and cancer. A better understanding of the mechanisms regulating adipose tissue expansion could lead to therapeutics that eliminate or reduce obesity-associated morbidity and mortality. The extracellular matrix (ECM) has been shown to regulate the development and function of numerous tissues and organs. However, there is little understanding of its function in adipose tissue. In this manuscript we describe the role of laminin α4, a specialized ECM protein surrounding adipocytes, on weight gain and adipose tissue function. Adipose tissue accumulation, lipogenesis, and structure were examined in mice with a null mutation of the laminin α4 gene (Lama4-/-) and compared to wild-type (Lama4+/+) control animals. Lama4-/- mice exhibited reduced weight gain in response to both age and high fat diet. Interestingly, the mice had decreased adipose tissue mass and altered lipogenesis in a depot-specific manner. In particular, epididymal adipose tissue mass was specifically decreased in knock-out mice, and there was also a defect in lipogenesis in this depot as well. In contrast, no such differences were observed in subcutaneous adipose tissue at 14 weeks. The results suggest that laminin α4 influences adipose tissue structure and function in a depot-specific manner. Alterations in laminin composition offers insight into the roll the ECM potentially plays in modulating cellular behavior in adipose tissue expansion.

  6. 78 FR 79058 - Culturally Significant Objects Imported for Exhibition Determinations: “Chinese Paintings from...

    Science.gov (United States)

    2013-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chinese Paintings from Japanese..., 2003), I hereby determine that the objects to be included in the exhibition ``Chinese Paintings...

  7. 77 FR 48199 - Culturally Significant Objects Imported for Exhibition Determinations: “Bernini: Sculpting in Clay”

    Science.gov (United States)

    2012-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Bernini: Sculpting in Clay'' SUMMARY... objects to be included in the exhibition ``Bernini: Sculpting in Clay,'' imported from abroad...

  8. 78 FR 68134 - Culturally Significant Objects Imported for Exhibition Determinations: “Renaissance to Goya...

    Science.gov (United States)

    2013-11-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Renaissance to Goya: Prints and... ``Renaissance to Goya: Prints and Drawings from Spain,'' imported from abroad for temporary exhibition within...

  9. 76 FR 70805 - Culturally Significant Objects Imported for Exhibition Determinations: “The Renaissance Portrait...

    Science.gov (United States)

    2011-11-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Renaissance Portrait From... ``The Renaissance Portrait from Donatello to Bellini,'' imported from abroad for temporary exhibition...

  10. 75 FR 62916 - Culturally Significant Objects Imported for Exhibition Determinations: “India's Fabled City: The...

    Science.gov (United States)

    2010-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``India's Fabled City: The Art of... ``India's Fabled City: The Art of Courtly Lucknow,'' imported from abroad for temporary exhibition...

  11. 78 FR 17744 - Culturally Significant Objects Imported for Exhibition Determinations: “Maya: Hidden Worlds...

    Science.gov (United States)

    2013-03-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Maya: Hidden Worlds Revealed... determine that the objects to be included in the exhibition ``Maya: Hidden Worlds Revealed,'' imported...

  12. 75 FR 45195 - Culturally Significant Objects Imported for Exhibition Determinations: “Literary Lives: Portraits...

    Science.gov (United States)

    2010-08-02

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Literary Lives: Portraits From the... that the objects to be included in the exhibition ``Literary Lives: Portraits from the Crawford...

  13. 76 FR 58075 - Culturally Significant Object Imported for Exhibition Determinations: “Cervera Bible”

    Science.gov (United States)

    2011-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Cervera Bible'' SUMMARY: Notice is... object to be included in the exhibition ``Cervera Bible,'' imported from abroad for temporary...

  14. 76 FR 4987 - Culturally Significant Objects Imported for Exhibition Determinations: “Bali: Art, Ritual...

    Science.gov (United States)

    2011-01-27

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Bali: Art, Ritual, Performance..., Ritual, Performance,'' imported from abroad for temporary exhibition within the United States, are...

  15. 77 FR 61468 - Culturally Significant Objects Imported for Exhibition Determinations: “Balthus: Cats and Girls”

    Science.gov (United States)

    2012-10-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Balthus: Cats and Girls'' SUMMARY... objects to be included in the exhibition ``Balthus: Cats and Girls,'' imported from abroad for...

  16. 78 FR 1916 - Culturally Significant Objects Imported for Exhibition; Determinations: “Impressionism, Fashion...

    Science.gov (United States)

    2013-01-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition; Determinations: ``Impressionism, Fashion, and..., 2003), I hereby determine that the objects to be included in the exhibition ``Impressionism, Fashion...

  17. 76 FR 12786 - Culturally Significant Objects Imported for Exhibition Determinations: “Charlotte Salomon: Life...

    Science.gov (United States)

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Charlotte Salomon: Life? Or Theatre... Salomon: Life? Or Theatre?'' imported from abroad for temporary exhibition within the United States,...

  18. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Diego Rivera: Murals for...

    Science.gov (United States)

    2011-10-13

    ... Imported for Exhibition Determinations: ``Diego Rivera: Murals for the Museum of Modern Art'' SUMMARY... objects to be included in the exhibition ``Diego Rivera: Murals for The Museum of Modern Art,'' imported...

  19. 76 FR 29286 - Culturally Significant Objects Imported for Exhibition Determinations: “Pissarro's People”

    Science.gov (United States)

    2011-05-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Pissarro's People'' SUMMARY: Notice..., I hereby determine that the objects to be included in the exhibition ``Pissarro's People,''...

  20. Modeling Information for Three-Dimensional Space: Lessons Learned from Museum Exhibit Design.

    Science.gov (United States)

    Carliner, Saul

    2001-01-01

    Reports results of an observational study of museum exhibit design. Suggests eight communication practices from successful museum exhibit design that could be transferred to information design for the Web. (SR)

  1. 76 FR 15358 - Culturally Significant Objects Imported for Exhibition Determinations: “Before the Pyramids: The...

    Science.gov (United States)

    2011-03-21

    ... ``Before the Pyramids: The Origins of Egyptian Civilization'' imported from abroad for temporary exhibition... Culturally Significant Objects Imported for Exhibition Determinations: ``Before the Pyramids: The Origins of Egyptian Civilization'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to...

  2. 76 FR 5236 - Culturally Significant Objects Imported for Exhibition Determinations: “Upside Down Arctic...

    Science.gov (United States)

    2011-01-28

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Upside Down Arctic Realities... Down Arctic Realities,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan agreements with the foreign owners...

  3. 77 FR 39319 - Culturally Significant Objects Imported for Exhibition Determinations: “Bodies and Shadows...

    Science.gov (United States)

    2012-07-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Bodies and Shadows: Caravaggio and...: Caravaggio and His Legacy'' imported from abroad for temporary exhibition within the United States, are...

  4. 78 FR 28274 - Culturally Significant Objects Imported for Exhibition Determinations: “Medieval Treasures from...

    Science.gov (United States)

    2013-05-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Medieval Treasures from Hildesheim... determine that the objects to be included in the exhibition ``Medieval Treasures from Hildesheim,''...

  5. 78 FR 61981 - Culturally Significant Objects Imported for Exhibition Determinations: “Anders Zorn: Sweden's...

    Science.gov (United States)

    2013-10-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Anders Zorn: Sweden's Master Painter... determine that the objects to be included in the exhibition ``Anders Zorn: Sweden's Master...

  6. 76 FR 12786 - Culturally Significant Objects Imported for Exhibition Determinations: “Poetry in Clay: Korean...

    Science.gov (United States)

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Poetry in Clay: Korean Buncheong... objects to be included in the exhibition ``Poetry in Clay: Korean Buncheong Ceramics from the...

  7. 75 FR 80885 - Culturally Significant Objects Imported for Exhibition Determinations: “The Buddhist Heritage of...

    Science.gov (United States)

    2010-12-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``The Buddhist Heritage of Pakistan... Buddhist Heritage of Pakistan,'' imported from abroad for temporary exhibition within the United...

  8. 75 FR 17197 - Culturally Significant Objects Imported for Exhibition Determinations: “Cyprus: Crossroads of...

    Science.gov (United States)

    2010-04-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Cyprus: Crossroads of Civilizations... that the objects to be included in the exhibition ``Cyprus: Crossroads of Civilizations,''...

  9. 75 FR 38589 - Culturally Significant Objects Imported for Exhibition Determinations: “Salvador Dali: The Late...

    Science.gov (United States)

    2010-07-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Salvador Dali: The Late Work... that the objects to be ] included in the exhibition ``Salvador Dali: The Late Work,'' imported...

  10. 77 FR 4614 - Culturally Significant Objects Imported for Exhibition Determinations: “Children of the Plumed...

    Science.gov (United States)

    2012-01-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Children of the Plumed Serpent: The... exhibition ``Children of the Plumed Serpent: The Legacy of Quetzalcoatl in Ancient Mexico,'' imported...

  11. 77 FR 32711 - Culturally Significant Objects Imported for Exhibition Determinations: “Messerschmidt and Modernity”

    Science.gov (United States)

    2012-06-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Messerschmidt and Modernity... ``Messerschmidt and Modernity,'' imported from abroad for temporary exhibition within the United States, are of...

  12. 78 FR 39435 - Culturally Significant Objects Imported for Exhibition; Determinations: “Magritte: The Mystery of...

    Science.gov (United States)

    2013-07-01

    ... Exhibition; Determinations: ``Magritte: The Mystery of the Ordinary, 1926-1938'' SUMMARY: Notice is hereby... objects to be included in the exhibition ``Magritte: The Mystery of the Ordinary, 1926-1928,'' imported...

  13. 78 FR 48925 - Culturally Significant Object Imported for Exhibition Determinations: “Violence and Virtue...

    Science.gov (United States)

    2013-08-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Violence and Virtue: Artemisia... April 15, 2003), I hereby determine that the object to be included in the exhibition ``Violence...

  14. 75 FR 51518 - Culturally Significant Objects Imported for Exhibition Determinations: “Ballplayers, Gods, and...

    Science.gov (United States)

    2010-08-20

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ballplayers, Gods, and Rainmaker... objects to be included in the exhibition ``Ballplayers, Gods, and Rainmaker Kings: Masterpieces...

  15. 76 FR 53993 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2011...

    Science.gov (United States)

    2011-08-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2011: Zhang Dali... objects to be included in the exhibition ``New Photography 2011: Zhang Dali, Moyra Davey, George...

  16. 77 FR 50542 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2012...

    Science.gov (United States)

    2012-08-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2012: Michele Abeles... objects to be included in the exhibition ``New Photography 2012: Michele Abeles, Birdhead (Ji Weiyu...

  17. 78 FR 40544 - Culturally Significant Objects Imported for Exhibition Determinations: “New Photography 2013...

    Science.gov (United States)

    2013-07-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``New Photography 2013: Adam Broomberg..., 2003), I hereby determine that the objects to be included in the exhibition ``New Photography...

  18. 78 FR 71022 - Culturally Significant Objects Imported for Exhibition Determinations: “Christopher Williams: The...

    Science.gov (United States)

    2013-11-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Christopher Williams: The Production..., 2003), I hereby determine that the objects to be included in the exhibition ``Christopher Williams:...

  19. 78 FR 8682 - Culturally Significant Object Imported for Exhibition Determinations: “Vermeer's Woman in Blue...

    Science.gov (United States)

    2013-02-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Vermeer's Woman in Blue Reading a... ``Vermeer's Woman in Blue Reading a Letter,'' imported from abroad for temporary exhibition within...

  20. 76 FR 20802 - Culturally Significant Object Imported for Exhibition Determinations: “The Capitoline Venus”

    Science.gov (United States)

    2011-04-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``The Capitoline Venus'' SUMMARY..., I hereby determine that the object to be included in the exhibition ``The Capitoline...

  1. 76 FR 23642 - Culturally Significant Objects Imported for Exhibition Determinations: “Projects 95: Runa Islam”

    Science.gov (United States)

    2011-04-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Projects 95: Runa Islam'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Projects 95: Runa...

  2. 76 FR 12399 - Culturally Significant Objects Imported for Exhibition Determinations: “Paris: Life & Luxury”

    Science.gov (United States)

    2011-03-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Paris: Life & Luxury'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Paris: Life &...

  3. 76 FR 14115 - Culturally Significant Objects Imported for Exhibition Determinations: “Assorted Greek and Roman...

    Science.gov (United States)

    2011-03-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Assorted Greek and Roman Objects... Greek and Roman Objects'' imported from abroad for temporary exhibition within the United States, are...

  4. 75 FR 57825 - Culturally Significant Objects Imported for Exhibition Determinations: “Ancient Chinese Bronzes...

    Science.gov (United States)

    2010-09-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Ancient Chinese Bronzes From the... objects to be included in the exhibition ``Ancient Chinese Bronzes from the Shouyang Studio: The...

  5. 75 FR 15764 - Culturally Significant Objects Imported for Exhibition Determinations: “Gods of Angkor: Bronzes...

    Science.gov (United States)

    2010-03-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Gods of Angkor: Bronzes From the...: Bronzes from the National Museum of Cambodia,'' imported from abroad for temporary exhibition within...

  6. 76 FR 63701 - Culturally Significant Objects Imported for Exhibition Determinations: “Anglo-Saxon Hoard: Gold...

    Science.gov (United States)

    2011-10-13

    ... for Exhibition Determinations: ``Anglo-Saxon Hoard: Gold From England's Dark Ages'' SUMMARY: Notice is... objects to be included in the exhibition ``Anglo-Saxon Hoard: Gold From England's Dark Ages,'' imported...

  7. 75 FR 74768 - Culturally Significant Objects Imported for Exhibition Determinations: “Norwegian Painters”

    Science.gov (United States)

    2010-12-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Norwegian Painters'' SUMMARY: Notice..., I hereby determine that the objects to be included in the exhibition ``Norwegian...

  8. 77 FR 56697 - Culturally Significant Objects Imported for Exhibition Determinations: “The English Prize: The...

    Science.gov (United States)

    2012-09-13

    ... for Exhibition Determinations: ``The English Prize: The Capture of the Westmorland, an Episode of the..., 2003), I hereby determine that the objects to be included in the exhibition ``The English Prize:...

  9. 77 FR 23318 - Culturally Significant Object Imported for Exhibition Determinations: “African Cosmos: Stellar Arts”

    Science.gov (United States)

    2012-04-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``African Cosmos: Stellar Arts... Cosmos: Stellar Arts,'' imported from abroad for temporary exhibition within the United States, is...

  10. 75 FR 45194 - Culturally Significant Objects Imported for Exhibition Determinations: “Drawing from Nature...

    Science.gov (United States)

    2010-08-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Drawing from Nature: Landscapes by... objects to be included in the exhibition ``Drawing from Nature: Landscapes by Max Liebermann, Lovis...

  11. 77 FR 34121 - Culturally Significant Objects Imported for Exhibition Determinations: “Lucian Freud: Portraits”

    Science.gov (United States)

    2012-06-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Lucian Freud: Portraits'' SUMMARY... object to be included in the exhibition ``Lucian Freud: Portraits,'' imported from abroad by The Modern...

  12. 75 FR 48736 - Culturally Significant Objects Imported for Exhibition Determinations: “Kurt Schwitters: Color...

    Science.gov (United States)

    2010-08-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Kurt Schwitters: Color and Collage... Schwitters: Color and Collage,'' imported from abroad for temporary exhibition within the United States,...

  13. 75 FR 25031 - Culturally Significant Objects Imported for Exhibition Determinations: “Tiffany: Color and Light”

    Science.gov (United States)

    2010-05-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Tiffany: Color and Light'' SUMMARY... included in the exhibition ``Tiffany: Color and Light,'' imported from abroad for temporary...

  14. 78 FR 4972 - Culturally Significant Objects Imported for Exhibition Determinations: “Chagall: Beyond Color”

    Science.gov (United States)

    2013-01-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Chagall: Beyond Color'' SUMMARY... objects to be included in the exhibition ``Chagall: Beyond Color,'' imported from abroad for...

  15. 77 FR 61045 - Culturally Significant Objects Imported for Exhibition Determinations: “China's Terracotta...

    Science.gov (United States)

    2012-10-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``China's Terracotta Warriors: The... Terracotta Warriors: The First Emperor's Legacy,'' imported from abroad for temporary exhibition within...

  16. 75 FR 82128 - Culturally Significant Objects Imported for Exhibition Determinations: “Vishnu: Hinduism's Blue...

    Science.gov (United States)

    2010-12-29

    ... for Exhibition Determinations: ``Vishnu: Hinduism's Blue-Skinned Savior'' SUMMARY: Notice is hereby... hereby determine that the objects to be included in the exhibition ``Vishnu: Hinduism's Blue-Skinned...

  17. 75 FR 1680 - Culturally Significant Objects Imported for Exhibition Determinations: “Roman Art”

    Science.gov (United States)

    2010-01-12

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Roman Art'' SUMMARY: Notice is... included in the exhibition ``Roman Art,'' imported from abroad for temporary exhibition within the United... the Metropolitan Museum of Art, New York, NY, from on or about January 2010 until on or about...

  18. The Particular Aspects of Science Museum Exhibits That Encourage Students' Engagement

    Science.gov (United States)

    Shaby, Neta; Assaraf, Orit Ben-Zvi; Tal, Tali

    2017-06-01

    This research explores learning in science museums through the most common activity in a science museum—interaction with exhibits. The goal of this study was to characterize the learning behaviors exhibited by students as they engage with interactive exhibits in order to draw insight regarding the design of the exhibits. In order to do so, we used a qualitative method of observation as well as the Visitor Engagement Framework (VEF) model, a visitor-based framework for assessing visitors' learning experiences with exhibits in a science center setting. The combined method produced a framework of nine learning behaviors exhibited during the visitors' interaction with the exhibits, grouped into three categories that reflect increasing levels of engagement and depth of the learning experience. Our research participants consisted of a total 1800 students aged 10-12 (4th, 5th, and 6th graders) who came to the museum with their class for a day visit. We observed nine exhibits, each visited by 200 students. Our observations revealed several design elements that contribute to engagement with exhibits in science museums. For example, exhibits that have familiar activation encourage visitors' interaction, exhibits that facilitate social interaction are more likely to increase engagement, and the highest levels of engagement can be found in exhibits that support large groups.

  19. The Particular Aspects of Science Museum Exhibits That Encourage Students' Engagement

    Science.gov (United States)

    Shaby, Neta; Assaraf, Orit Ben-Zvi; Tal, Tali

    2016-12-01

    This research explores learning in science museums through the most common activity in a science museum—interaction with exhibits. The goal of this study was to characterize the learning behaviors exhibited by students as they engage with interactive exhibits in order to draw insight regarding the design of the exhibits. In order to do so, we used a qualitative method of observation as well as the Visitor Engagement Framework (VEF) model, a visitor-based framework for assessing visitors' learning experiences with exhibits in a science center setting. The combined method produced a framework of nine learning behaviors exhibited during the visitors' interaction with the exhibits, grouped into three categories that reflect increasing levels of engagement and depth of the learning experience. Our research participants consisted of a total 1800 students aged 10-12 (4th, 5th, and 6th graders) who came to the museum with their class for a day visit. We observed nine exhibits, each visited by 200 students. Our observations revealed several design elements that contribute to engagement with exhibits in science museums. For example, exhibits that have familiar activation encourage visitors' interaction, exhibits that facilitate social interaction are more likely to increase engagement, and the highest levels of engagement can be found in exhibits that support large groups.

  20. 77 FR 22833 - Culturally Significant Objects Imported for Exhibition Determinations: “Edouard Vuillard: A...

    Science.gov (United States)

    2012-04-17

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Edouard Vuillard: A Painter and His... pertaining to the exhibit ``Edouard Vuillard: A Painter and His Muses, 1890-1940.'' The reference notice is... exhibition ``Edouard Vuillard: A Painter and His Muses, 1890-1940,'' imported from abroad for temporary...

  1. Value and Audience Relationships: Tate’s Ticketed Exhibitions 2014–15

    Directory of Open Access Journals (Sweden)

    Mariza Dima

    2016-06-01

    Full Text Available In this report Mariza Dima sets out the findings of a research project examining the experiential and educational value of Tate’s ticketed exhibitions to its audiences. Exhibition planning, the contributions of small and medium-sized enterprises and the museum’s data-gathering practices are explored, taking the 2014 exhibitions Late Turner and Malevich as case studies.

  2. 78 FR 26682 - Culturally Significant Objects Imported for Exhibition Determinations: “Hall of Ancient Egypt”

    Science.gov (United States)

    2013-05-07

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Hall of Ancient Egypt'' AGENCY... pertaining to the exhibition ``Hall of Ancient Egypt.'' The referenced notice is corrected here to include... April 15, 2003), I hereby determine that the additional objects to be included in the exhibition...

  3. 78 FR 20372 - Culturally Significant Objects Imported for Exhibition Determinations: “Hall of Ancient Egypt”

    Science.gov (United States)

    2013-04-04

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Hall of Ancient Egypt'' SUMMARY... objects to be included in the exhibition ``Hall of Ancient Egypt,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to...

  4. 77 FR 4858 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantium and Islam: Age...

    Science.gov (United States)

    2012-01-31

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantium and Islam: Age of... determinations made by ] the Department of State pertaining to the exhibition ``Byzantium and Islam: Age of... Islam: Age of Transition (7th-9th Century),'' imported from abroad for temporary exhibition within...

  5. Liquid-Crystalline Star-Shaped Supergelator Exhibiting Aggregation-Induced Blue Light Emission.

    Science.gov (United States)

    Pathak, Suraj Kumar; Pradhan, Balaram; Gupta, Monika; Pal, Santanu Kumar; Sudhakar, Achalkumar Ammathnadu

    2016-09-13

    A family of closely related star-shaped stilbene-based molecules containing an amide linkage are synthesized, and their self-assembly in liquid-crystalline and gel states was investigated. The number and position of the peripheral alkyl tails were systematically varied to understand the structure-property relation. Interestingly, one of the molecules with seven peripheral chains was bimesomorphic, exhibiting columnar hexagonal and columnar rectangular phases, whereas the rest of them stabilized the room-temperature columnar hexagonal phase. The self-assembly of these molecules in liquid-crystalline and organogel states is extremely sensitive to the position and number of alkoxy tails in the periphery. Two of the compounds with six and seven peripheral tails exhibited supergelation behavior in long-chain hydrocarbon solvents. One of these compounds with seven alkyl chains was investigated further, and it has shown higher stability and moldability in the gel state. The xerogel of the same compound was characterized with the help of extensive microscopic and X-ray diffraction studies. The nanofibers in the xerogel are found to consist of molecules arranged in a lamellar fashion. Furthermore, this compound shows very weak emission in solution but an aggregation-induced emission property in the gel state. Considering the dearth of solid-state blue-light-emitting organic materials, this molecular design is promising where the self-assembly and emission in the aggregated state can be preserved. The nonsymmetric design lowers the phase-transition temperatures.The presence of an amide bond helps to stabilize columnar packing over a long range because of its polarity and intermolecular hydrogen bonding in addition to promoting organogelation.

  6. Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics

    Directory of Open Access Journals (Sweden)

    Fikret Emre eKapucu

    2012-06-01

    Full Text Available In this paper we propose a firing statistics based neuronal network burst detection algorithm for neuronal networks exhibiting highly variable action potential dynamics. Electrical activity of neuronal networks is generally analyzed by the occurrences of spikes and bursts both in time and space. Commonly accepted analysis tools employ burst detection algorithms based on predefined criteria. However, maturing neuronal networks, such as those originating from human embryonic stem cells (hESC, exhibit highly variable network structure and time-varying dynamics. To explore the developing burst/spike activities of such networks, we propose a burst detection algorithm which utilizes the firing statistics based on interspike interval (ISI histograms. Moreover, the algorithm calculates interspike interval thresholds for burst spikes as well as for pre-burst spikes and burst tails by evaluating the cumulative moving average and skewness of the ISI histogram. Because of the adaptive nature of the proposed algorithm, its analysis power is not limited by the type of neuronal cell network at hand. We demonstrate the functionality of our algorithm with two different types of microelectrode array (MEA data recorded from spontaneously active hESC-derived neuronal cell networks. The same data was also analyzed by two commonly employed burst detection algorithms and the differences in burst detection results are illustrated. The results demonstrate that our method is both adaptive to the firing statistics of the network and yields successful burst detection from the data. In conclusion, the proposed method is a potential tool for analyzing of hESC-derived neuronal cell networks and thus can be utilized in studies aiming to understand the development and functioning of human neuronal networks and as an analysis tool for in vitro drug screening and neurotoxicity assays.

  7. Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics.

    Science.gov (United States)

    Kapucu, Fikret E; Tanskanen, Jarno M A; Mikkonen, Jarno E; Ylä-Outinen, Laura; Narkilahti, Susanna; Hyttinen, Jari A K

    2012-01-01

    In this paper we propose a firing statistics based neuronal network burst detection algorithm for neuronal networks exhibiting highly variable action potential dynamics. Electrical activity of neuronal networks is generally analyzed by the occurrences of spikes and bursts both in time and space. Commonly accepted analysis tools employ burst detection algorithms based on predefined criteria. However, maturing neuronal networks, such as those originating from human embryonic stem cells (hESCs), exhibit highly variable network structure and time-varying dynamics. To explore the developing burst/spike activities of such networks, we propose a burst detection algorithm which utilizes the firing statistics based on interspike interval (ISI) histograms. Moreover, the algorithm calculates ISI thresholds for burst spikes as well as for pre-burst spikes and burst tails by evaluating the cumulative moving average (CMA) and skewness of the ISI histogram. Because of the adaptive nature of the proposed algorithm, its analysis power is not limited by the type of neuronal cell network at hand. We demonstrate the functionality of our algorithm with two different types of microelectrode array (MEA) data recorded from spontaneously active hESC-derived neuronal cell networks. The same data was also analyzed by two commonly employed burst detection algorithms and the differences in burst detection results are illustrated. The results demonstrate that our method is both adaptive to the firing statistics of the network and yields successful burst detection from the data. In conclusion, the proposed method is a potential tool for analyzing of hESC-derived neuronal cell networks and thus can be utilized in studies aiming to understand the development and functioning of human neuronal networks and as an analysis tool for in vitro drug screening and neurotoxicity assays.

  8. An uncharacterized member of the ribokinase family in Thermococcus kodakarensis exhibits myo-inositol kinase activity.

    Science.gov (United States)

    Sato, Takaaki; Fujihashi, Masahiro; Miyamoto, Yukika; Kuwata, Keiko; Kusaka, Eriko; Fujita, Haruo; Miki, Kunio; Atomi, Haruyuki

    2013-07-19

    Here we performed structural and biochemical analyses on the TK2285 gene product, an uncharacterized protein annotated as a member of the ribokinase family, from the hyperthermophilic archaeon Thermococcus kodakarensis. The three-dimensional structure of the TK2285 protein resembled those of previously characterized members of the ribokinase family including ribokinase, adenosine kinase, and phosphofructokinase. Conserved residues characteristic of this protein family were located in a cleft of the TK2285 protein as in other members whose structures have been determined. We thus examined the kinase activity of the TK2285 protein toward various sugars recognized by well characterized ribokinase family members. Although activity with sugar phosphates and nucleosides was not detected, kinase activity was observed toward d-allose, d-lyxose, d-tagatose, d-talose, d-xylose, and d-xylulose. Kinetic analyses with the six sugar substrates revealed high Km values, suggesting that they were not the true physiological substrates. By examining activity toward amino sugars, sugar alcohols, and disaccharides, we found that the TK2285 protein exhibited prominent kinase activity toward myo-inositol. Kinetic analyses with myo-inositol revealed a greater kcat and much lower Km value than those obtained with the monosaccharides, resulting in over a 2,000-fold increase in kcat/Km values. TK2285 homologs are distributed among members of Thermococcales, and in most species, the gene is positioned close to a myo-inositol monophosphate synthase gene. Our results suggest the presence of a novel subfamily of the ribokinase family whose members are present in Archaea and recognize myo-inositol as a substrate.

  9. Bridging Mediterranean cultures in the IYS: A documentary exhibition on irrigation techniques in water scarcity conditions

    Science.gov (United States)

    Barontini, Stefano; Louki, Amina; Ben Slima, Zied; Ezzahra Ghaouch, Fatima; Labaran, Raisa; Raffelli, Giulia; Peli, Marco; Vitale, Nicola

    2015-04-01

    Brescia, an industrial city in Northern Italy, is now experiencing a crucial change in its traditional structure. In recent years in fact it has been elected as living and working seat by many foreigners and it is now one of the cities with the greatest percentage of migrants in the Country. This is an important challenge for the city and an opportunity to merge, compare and integrate different cultures to build its future. In this context some students of different Courses (engineering and medicine), belonging both to the Arabian and local community, met together and with researchers in the study team 'Al-B¯i r¯u n¯i , for culture, science and society'. The team aims at organising cultural events in which, starting from the figure of the Persian scientist Ab¯u Raih. ¯a n Al-B¯i r¯u n¯i (about 973, 1051), the contribution of the Arabian and Islamic culture to the development of the European one in the middle ages is investigated. Moving from the initial idea of the study team Al-B¯i r¯u n¯i and from the suggestions of the World Soil Day 2014 and of the International Year of Soils 2015, we built a documentary exhibition entitled 'Irrigation techniques in water scarcity conditions'. The exhibition, which stresses the importance of the irrigation techniques for the soil conservation, is focused on the idea of disseminating two main concepts, i.e. (1) the technological continuity of some water supply systems in countries, around the Mediterranean Sea, affected by similar conditions of water availability, and (2) the possibility of building environments where, due to severe or extreme climatic conditions, the sustainability is reached when the man lives in equilibrium with the nature. The exhibition, which is written in Italian and will move around in the city during all 2015, consists of about twenty posters organized into three main chapters, corresponding to three main classes of water supply systems which are common in most of the countries surrounding

  10. Using NLM exhibits and events to engage library users and reach the community.

    Science.gov (United States)

    Auten, Beth; Norton, Hannah F; Tennant, Michele R; Edwards, Mary E; Stoyan-Rosenzweig, Nina; Daley, Matthew

    2013-01-01

    In an effort to reach out to library users and make the library a more relevant, welcoming place, the University of Florida's Health Science Center Library hosted exhibits from the National Library of Medicine's (NLM) Traveling Exhibition Program. From 2010 through 2012, the library hosted four NLM exhibits and created event series for each. Through reflection and use of a participant survey, lessons were learned concerning creating relevant programs, marketing events, and forming new partnerships. Each successive exhibit added events and activities to address different audiences. A survey of libraries that have hosted NLM exhibits highlights lessons learned at those institutions.

  11. Extending the Library’s Web Presence: Building an Online Timeline Using MIT’s SIMILE Exhibit

    Directory of Open Access Journals (Sweden)

    Joe J. Marquez

    2012-01-01

    Full Text Available Extending the library’s presence beyond a brick and mortar structure is essential as resources become increasingly available in electronic format. One way to achieve this is to create a broad-reaching tool like a timeline using the Massachusetts Institute of Technology’s Semantic Interoperability of Metadata and Information in unLike Environments Exhibit (MIT’s SIMILE Exhibit, a cloud-based program that allows for the creation of data-driven websites with minimal programming or Web expertise. With this easy-to-learn technology, a library can extend its Web presence by providing online access to its rich historical collections. This article is a case study on the implementation of an online timeline, the “Sonoma County Timeline”, which was used to showcase the library’s resources at Sonoma State University. The author also demonstrates how to build a timeline using MIT’s SIMILE Exhibit software, and how a timeline can be used to extend the library’s presence to its community. A guide to managing the project, a status report for the Sonoma State University Library’s instance of Exhibit, and a discussion of best practices are also detailed in the article.

  12. A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei exhibits cytolytic activities.

    Science.gov (United States)

    Kuhn-Nentwig, Lucia; Fedorova, Irina M; Lüscher, Benjamin P; Kopp, Lukas S; Trachsel, Christian; Schaller, Johann; Vu, Xuan Lan; Seebeck, Thomas; Streitberger, Kathrin; Nentwig, Wolfgang; Sigel, Erwin; Magazanik, Lev G

    2012-07-20

    CsTx-1, the main neurotoxic acting peptide in the venom of the spider Cupiennius salei, is composed of 74 amino acid residues, exhibits an inhibitory cysteine knot motif, and is further characterized by its highly cationic charged C terminus. Venom gland cDNA library analysis predicted a prepropeptide structure for CsTx-1 precursor. In the presence of trifluoroethanol, CsTx-1 and the long C-terminal part alone (CT1-long; Gly-45-Lys-74) exhibit an α-helical structure, as determined by CD measurements. CsTx-1 and CT1-long are insecticidal toward Drosophila flies and destroys Escherichia coli SBS 363 cells. CsTx-1 causes a stable and irreversible depolarization of insect larvae muscle cells and frog neuromuscular preparations, which seem to be receptor-independent. Furthermore, this membranolytic activity could be measured for Xenopus oocytes, in which CsTx-1 and CT1-long increase ion permeability non-specifically. These results support our assumption that the membranolytic activities of CsTx-1 are caused by its C-terminal tail, CT1-long. Together, CsTx-1 exhibits two different functions; as a neurotoxin it inhibits L-type Ca(2+) channels, and as a membranolytic peptide it destroys a variety of prokaryotic and eukaryotic cell membranes. Such a dualism is discussed as an important new mechanism for the evolution of spider venomous peptides.

  13. Staphylococcus aureus exhibit similarities in their interactions with Acanthamoeba and ThP1 macrophage-like cells.

    Science.gov (United States)

    Cardas, Mihaela; Khan, Naveed Ahmed; Alsam, Selwa

    2012-12-01

    Staphylococcus aureus is a leading cause of nosocomial infections. Haematogenous spread is a pre-requisite but it is not clear how S. aureus survive the onslaught of macrophages. Acanthamoeba is a protozoan pathogen that is remarkably similar to macrophages, particularly in their cellular structure (morphological and ultra-structural features), molecular motility, biochemical physiology, ability to capture prey by phagocytosis and interactions with microbial pathogens. Thus, we hypothesize that S. aureus exhibit similarities in their interactions with Acanthamoeba and ThP1 macrophage-like cells. Here, we studied interactions of methicillin-sensitive S. aureus (MSSA), methicillin-resistant S. aureus (MRSA) and Staphylococcus epidermidis (SE) with Acanthamoeba castellanii belonging to the T4 genotype and macrophage-like cells (ThP1). The findings revealed that both MRSA and MSSA exhibited similarities in their binding/association and invasion of A. castellanii and ThP1 cells. Long-term incubation showed that MRSA and MSSA can survive intracellularly of both Acanthamoeba and ThP1 cells. Overall, these findings suggest that Acanthamoeba exhibit similar characteristics with ThP1 macrophage-like cells in their interaction with MRSA and MSSA. Additionally it was shown that bacteria survive inside Acanthamoeba during the encystment process as evidenced by bacterial recovery from mature cysts. Given that Acanthamoeba cysts are airborne, these findings suggest that cysts may act as "Trojan horse" to help spread MRSA to susceptible hosts.

  14. Cancer cells recovering from damage exhibit mitochondrial restructuring and increased aerobic glycolysis

    Energy Technology Data Exchange (ETDEWEB)

    Akakura, Shin; Ostrakhovitch, Elena; Sanokawa-Akakura, Reiko [Frontiers in Bioscience Research Institute in Aging and Cancer, University of California, Irvine, CA (United States); Tabibzadeh, Siamak, E-mail: fbs@bioscience.org [Frontiers in Bioscience Research Institute in Aging and Cancer, University of California, Irvine, CA (United States); Dept of Oncologic Radiology, University of California, Irvine, CA (United States)

    2014-06-13

    Highlights: • Some cancer cells recover from severe damage that causes cell death in majority of cells. • Damage-Recovered (DR) cancer cells show reduced mitochondria, mDNA and mitochondrial enzymes. • DR cells show increased aerobic glycolysis, ATP, cell proliferation, and resistance to damage. • DR cells recovered from in vivo damage also show increased glycolysis and proliferation rate. - Abstract: Instead of relying on mitochondrial oxidative phosphorylation, most cancer cells rely heavily on aerobic glycolysis, a phenomenon termed as “the Warburg effect”. We considered that this effect is a direct consequence of damage which persists in cancer cells that recover from damage. To this end, we studied glycolysis and rate of cell proliferation in cancer cells that recovered from severe damage. We show that in vitro Damage-Recovered (DR) cells exhibit mitochondrial structural remodeling, display Warburg effect, and show increased in vitro and in vivo proliferation and tolerance to damage. To test whether cancer cells derived from tumor microenvironment can show similar properties, we isolated Damage-Recovered (T{sup DR}) cells from tumors. We demonstrate that T{sup DR} cells also show increased aerobic glycolysis and a high proliferation rate. These findings show that Warburg effect and its consequences are induced in cancer cells that survive severe damage.

  15. Criticality is an emergent property of genetic networks that exhibit evolvability.

    Directory of Open Access Journals (Sweden)

    Christian Torres-Sosa

    Full Text Available Accumulating experimental evidence suggests that the gene regulatory networks of living organisms operate in the critical phase, namely, at the transition between ordered and chaotic dynamics. Such critical dynamics of the network permits the coexistence of robustness and flexibility which are necessary to ensure homeostatic stability (of a given phenotype while allowing for switching between multiple phenotypes (network states as occurs in development and in response to environmental change. However, the mechanisms through which genetic networks evolve such critical behavior have remained elusive. Here we present an evolutionary model in which criticality naturally emerges from the need to balance between the two essential components of evolvability: phenotype conservation and phenotype innovation under mutations. We simulated the Darwinian evolution of random Boolean networks that mutate gene regulatory interactions and grow by gene duplication. The mutating networks were subjected to selection for networks that both (i preserve all the already acquired phenotypes (dynamical attractor states and (ii generate new ones. Our results show that this interplay between extending the phenotypic landscape (innovation while conserving the existing phenotypes (conservation suffices to cause the evolution of all the networks in a population towards criticality. Furthermore, the networks produced by this evolutionary process exhibit structures with hubs (global regulators similar to the observed topology of real gene regulatory networks. Thus, dynamical criticality and certain elementary topological properties of gene regulatory networks can emerge as a byproduct of the evolvability of the phenotypic landscape.

  16. Mouse Proepicardium Exhibits a Sprouting Response to Exogenous Proangiogenic Growth Factors in vitro.

    Science.gov (United States)

    Niderla-Bielińska, Justyna; Ciszek, Bogdan; Jankowska-Steifer, Ewa; Flaht-Zabost, Aleksandra; Gula, Grzegorz; Radomska-Leśniewska, Dorota M; Ratajska, Anna

    2016-01-01

    Angiogenesis contributes to the generation of the vascular bed but also affects the progression of many diseases, such as tumor growth. Many details of the molecular pathways controlling angiogenesis are still undefined due to the lack of appropriate models. We propose the proepicardial explant as a suitable model for studying certain aspects of angiogenesis. The proepicardium (PE) is a transient embryonic structure that contains a population of undifferentiated endothelial cells (ECs) forming a vascular net continuous with the sinus venosus. In this paper, we show that PE explants give rise to CD31-positive vascular sprouts in the presence of basic fibroblast growth factor (bFGF) and 2 isoforms of vascular endothelial growth factor A (VEGF-A), i.e. VEGF-A120 and VEGF-A164. Vascular sprouts exhibit differences in number, length, thickness and the number of branches, depending on the combination of growth factors used. Moreover, the ECs of the sprouts express various levels of mRNA for Notch1 and its ligand Dll4. Additionally, stimulation with bFGF/VEGF-A164 upregulates the expression of Lyve-1 antigen in the ECs in the sprouts. In summary, we present a new model for angiogenesis studies involving mouse PE as a source of ECs. We believe that our model may act as a supplementary assay for angiogenesis studies along with the existing models.

  17. A zinc phthalocyanine based periodic mesoporous organosilica exhibiting charge transfer to fullerenes.

    Science.gov (United States)

    Auras, Florian; Li, Yan; Löbermann, Florian; Döblinger, Markus; Schuster, Jörg; Peter, Laurence M; Trauner, Dirk; Bein, Thomas

    2014-11-10

    Periodic mesoporous organosilica (PMO) materials offer a strategy to position molecular semiconductors within a highly defined, porous network. We developed thin films of a new semiconducting zinc phthalocyanine-bridged PMO exhibiting a face-centered orthorhombic pore structure with an average pore diameter of 11 nm. The exceptional degree of order achieved with this PMO enabled us to create thin films consisting of a single porous domain throughout their entire thickness, thus providing maximal accessibility for subsequent incorporation of a complementary phase. The phthalocyanine building blocks inside the pore walls were found to be well-aggregated, enabling electronic conductivity and extending the light-harvesting capabilities to the near IR region. Ordered 3D heterojunctions capable of promoting photo-induced charge transfer were constructed by impregnation of the PMO with a fullerene derivative. When integrated into a photovoltaic device, the infiltrated PMO is capable of producing a high open-circuit voltage and a considerable photocurrent, which represents a significant step towards potential applications of PMOs in optoelectronics. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Halogenated pentamethine cyanine dyes exhibiting high fidelity for G-quadruplex DNA.

    Science.gov (United States)

    Nanjunda, Rupesh; Owens, Eric A; Mickelson, Leah; Alyabyev, Sergey; Kilpatrick, Nancy; Wang, Siming; Henary, Maged; Wilson, W David

    2012-12-15

    Design and optimization of quadruplex-specific small molecules is developing into an attractive strategy for anti-cancer therapeutics with some promising candidates in clinical trials. A number of therapeutically favorable features of cyanine molecules can be effectively exploited to develop them as promising quadruplex-targeting agents. Herein, the design, synthesis and evaluation of a series of dimethylindolenine cyanine dyes with varying halogen substitutions are reported. Their interactions with telomeric and c-myc quadruplexes as well as a reference duplex sequence have been evaluated using thermal melting, biosensor-surface plasmon resonance, circular dichroism, isothermal titration calorimetry and mass spectrometry. Thermal melting analysis indicates that these ligands exhibit significant quadruplex stabilization and a very low duplex binding, with the dimethyl incorporation of paramount importance for decreased duplex affinity. Circular dichroism studies showed that the interaction of cyanines with quadruplex structures are primarily through stacking at one or both ends of the terminal tetrads with the two (trimethylammonium)propyl groups interacting in the accessible quadruplex grooves. Surface plasmon resonance and mass spectral studies shows the formation of an initial strong 1:1 complex followed by a significantly weaker secondary binding. Isothermal calorimetry studies show that the interaction of cyanines is predominantly entropy driven. In line with the design principles, this work provides new insights for further developing potent, highly selective cyanines as promising quadruplex-specific agents.

  19. Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues.

    Directory of Open Access Journals (Sweden)

    William A Munoz

    Full Text Available The p120-catenin family has undergone a significant expansion during the evolution of vertebrates, resulting in varied functions that have yet to be discerned or fully characterized. Likewise, members of the plakophilins, a related catenin subfamily, are found throughout the cell with little known about their functions outside the desmosomal plaque. While the plakophilin-3 (Pkp3 knockout mouse resulted in skin defects, we find larger, including lethal effects following its depletion in Xenopus. Pkp3, unlike some other characterized catenins in amphibians, does not have significant maternal deposits of mRNA. However, during embryogenesis, two Pkp3 protein products whose temporal expression is partially complimentary become expressed. Only the smaller of these products is found in adult Xenopus tissues, with an expression pattern exhibiting distinctions as well as overlaps with those observed in mammalian studies. We determined that Xenopus Pkp3 depletion causes a skin fragility phenotype in keeping with the mouse knockout, but more novel, Xenopus tailbud embryos are hyposensitive to touch even in embryos lacking outward discernable phenotypes, and we additionally resolved disruptions in certain peripheral neural structures, altered establishment and migration of neural crest, and defects in ectodermal multiciliated cells. The use of two distinct morpholinos, as well as rescue approaches, indicated the specificity of these effects. Our results point to the requirement of Pkp3 in amphibian embryogenesis, with functional roles in a number of tissue types.

  20. Spirocyclic chromanes exhibit antiplasmodial activities and inhibit all intraerythrocytic life cycle stages.

    Science.gov (United States)

    Roberts, Bracken F; Iyamu, Iredia D; Lee, Sukjun; Lee, Eunyoung; Ayong, Lawrence; Kyle, Dennis E; Yuan, Yu; Manetsch, Roman; Chakrabarti, Debopam

    2016-04-01

    We screened a collection of synthetic compounds consisting of natural-product-like substructural motifs to identify a spirocyclic chromane as a novel antiplasmodial pharmacophore using an unbiased cell-based assay. The most active spirocyclic compound UCF 201 exhibits a 50% effective concentration (EC50) of 350 nM against the chloroquine-resistant Dd2 strain and a selectivity over 50 using human liver HepG2 cells. Our analyses of physicochemical properties of UCF 201 showed that it is in compliance with Lipinski's parameters and has an acceptable physicochemical profile. We have performed a limited structure-activity-relationship study with commercially available chromanes preserving the spirocyclic motif. Our evaluation of stage specificities of UCF 201 indicated that the compound is early-acting in blocking parasite development at ring, trophozoite and schizont stages of development as well as merozoite invasion. SPC is an attractive lead candidate scaffold because of its ability to act on all stages of parasite's aexual life cycle unlike current antimalarials.