WorldWideScience

Sample records for psubscript rep statistics

  1. Killeen's (2005) "p[subscript rep]" Coefficient: Logical and Mathematical Problems

    Science.gov (United States)

    Maraun, Michael; Gabriel, Stephanie

    2010-01-01

    In his article, "An Alternative to Null-Hypothesis Significance Tests," Killeen (2005) urged the discipline to abandon the practice of "p[subscript obs]"-based null hypothesis testing and to quantify the signal-to-noise characteristics of experimental outcomes with replication probabilities. He described the coefficient that he…

  2. Statistical Study of the Occurrence of POES Relativistic Electron Precipitation (REP) in Correlation with Electromagnetic Ion Cyclotron (EMIC) Waves

    Science.gov (United States)

    Hembeck, J.; Lessard, M.; Engebretson, M. J.; Rodger, C. J.; Hendry, A.

    2016-12-01

    Electromagnetic Ion Cyclotron (EMIC) waves are phenomena that exist within the Earth's magnetosphere caused by an ion temperature anisotropy. The ideal conditions for EMIC wave growth occur during solar storms. In this statistical study, Polar Orbiting Environmental Satellites (POES) relativistic electron precipitation (REP) data are compared to EMIC wave data from Halley Bay in the years ranging from 2008-2010. This statistical study considers a specific type of EMIC wave events known as Intervals of Pulsations of Diminishing Periods (IPDP) to see whether this type of EMIC wave causes a statistically greater occurrence of REP. In this study, different types of IPDP are characterized based on the increase in frequency over time of each wave form. Another considered characteristic of the IPDP waves is whether the wave is continuous or appears as discrete packets, which may actually be separate events. IPDP events are cataloged and then compared to REP events from the POES data set, forming a study that is complementary to that of Hendry et al. [2016], who compared REP from POES data to the presence of EMIC waves at Halley Bay.

  3. Utshitsja drug u druga / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2005-01-01

    Haridus- ja teadusminister Mailis Reps uuendustest koolide õppekavades, õpetajate täienduskoolituse tähtsusest, kutsehariduse arengust, tasuta toitlustamisest põhi- ja kutsekoolides, õpetajate palkadest

  4. Statistics

    CERN Document Server

    Hayslett, H T

    1991-01-01

    Statistics covers the basic principles of Statistics. The book starts by tackling the importance and the two kinds of statistics; the presentation of sample data; the definition, illustration and explanation of several measures of location; and the measures of variation. The text then discusses elementary probability, the normal distribution and the normal approximation to the binomial. Testing of statistical hypotheses and tests of hypotheses about the theoretical proportion of successes in a binomial population and about the theoretical mean of a normal population are explained. The text the

  5. Statistics

    Science.gov (United States)

    Links to sources of cancer-related statistics, including the Surveillance, Epidemiology and End Results (SEER) Program, SEER-Medicare datasets, cancer survivor prevalence data, and the Cancer Trends Progress Report.

  6. Adeno-associated virus rep protein synthesis during productive infection

    Energy Technology Data Exchange (ETDEWEB)

    Redemann, B.E.; Mendelson, E.; Carter, B.J.

    1989-02-01

    Adeno-associated virus (AAV) Rep proteins mediate viral DNA replication and can regulate expression from AAV genes. The authors studied the kinetics of synthesis of the four Rep proteins, Rep78, Rep68, Rep52, and Rep40, during infection of human 293 or KB cells with AAV and helper adenovirus by in vivo labeling with (/sup 35/S)methionine, immunoprecipitation, and immunoblotting analyses. Rep78 and Rep52 were readily detected concomitantly with detection of viral monomer duplex DNA replicating about 10 to 12 h after infection, and Rep68 and Rep40 were detected 2 h later. Rep78 and Rep52 were more abundant than Rep68 and Rep40 owing to a higher synthesis rate throughout the infectious cycle. In some experiments, very low levels of Rep78 could be detected as early as 4 h after infection. The synthesis rates of Rep proteins were maximal between 14 and 24 h and then decreased later after infection. Isotopic pulse-chase experiments showed that each of the Rep proteins was synthesized independently and was stable for at least 15 h. A slower-migrating, modified form of Rep78 was identified late after infection. AAV capsid protein synthesis was detected at 10 to 12 h after infection and also exhibited synthesis kinetics similar to those of the Rep proteins. AAV DNA replication showed at least two clearly defined stages. Bulk duplex replicating DNA accumulation began around 10 to 12 h and reached a maximum level at about 20 h when Rep and capsid protein synthesis was maximal. Progeny single-stranded DNA accumulation began about 12 to 13 h, but most of this DNA accumulated after 24 h when Rep and capsid protein synthesis had decreased.

  7. COMPARATIVE ANALYSIS OF THE REPS NUMBER WITHIN TWO TRAINING MACROCYCLES OF THE WEIGHTLIFTING OLYMPIC TEAM

    Directory of Open Access Journals (Sweden)

    ULĂREANU MARIUS VIOREL

    2010-12-01

    Full Text Available The authors present a comparative analysis of the number of repetitions in two training macro-cycles of the weightlifting Olympic team. We have considered that the differences between the number of reps in each training stage of the macro-cycles no. 1 and 2 will influence the performances achieved in competition. This approach has led to the organization of a study group in the weightlifting Olympic team of Romania. The scientific argument is the presentation of the number of reps during the preparation of the weightlifting Olympic team in different mezzo and micro-cycles of training, that, by decreasing the number of reps and increasing the intensity of the effort up to the maximum level from a training micro-cycle to another,contributes to reaching the fitness peak in competitive period within the macro-cycle no.1; also, an optimum number of reps during the training macro-cycle no.2 will make possible to keep the fitness necessary for their turning into good account in the next competition.The study was conducted over a period of two training macro-cycles (04.01-16.08.2008, with a group of 6 athletes, of 17 to 31 years old, whose target of performance was the participation in the EuropeanChampionships (E. C. for Seniors, Lignano – Sabbiadoro, Italy 2008 and the Olympic Games (J.O. in Beijing in 2008. The athletes’ progresses during the training stages and competitions were recorded by means of the statistical-mathematical and plotting methods.The study highlights the number of reps within two training macro-cycles of the weightlifting Olympic team. At the end of the paper we are able to confirm that the differences between the number of reps at each stage of training in the macro-cycles no. 1 and 2 have influenced the performances achieved in competition

  8. The Use of HepRep in GLAST

    Energy Technology Data Exchange (ETDEWEB)

    Perl, Joseph

    2003-07-10

    HepRep is a generic, hierarchical format for description of graphics representables that can be augmented by physics information and relational properties. It was developed for high energy physics event display applications and is especially suited to client/server or component frameworks. The GLAST experiment, an international effort led by NASA for a gamma-ray telescope to launch in 2006, chose HepRep to provide a flexible, extensible and maintainable framework for their event display without tying their users to any one graphics application. To support HepRep in their GUADI infrastructure, GLAST developed a HepRep filler and builder architecture. The architecture hides the details of XML and CORBA in a set of base and helper classes allowing physics experts to focus on what data they want to represent. GLAST has two GAUDI services: HepRepSvc, which registers HepRep fillers in a global registry and allows the HepRep to be exported to XML, and CorbaSvc, which allows the HepRep to be published through a CORBA interface and which allows the client application to feed commands back to GAUDI (such as start next event, or run some GAUDI algorithm). GLAST's HepRep solution gives users a choice of client applications, WIRED (written in Java) or FRED (written in C++ and Ruby), and leaves them free to move to any future HepRep-compliant event display.

  9. Pensar la República: revolución y positivismo en los orígenes de la tercera república francesa

    OpenAIRE

    López Alcañiz, Vladimir

    2005-01-01

    El artículo reflexiona entorno la idea de república durante la tercera república francesa. El artículo incluye una bibliografía comentada referente al legado de la Revolución y los orígenes de la República. L’article reflexiona entorn la idea de república durant la tercera república francesa. L’article inclou una bibliografia comentada referent al llegat de la Revolució i els orígens de la República. The article focus on republic thought during the third french republic. It includes a b...

  10. República Saharaui: una nación cerca del olvido

    OpenAIRE

    Valdez Ugalde, María Cristina

    2010-01-01

    1. Párrafo de Inicio 2. Desarrollo a. República Saharaui o Sahara Occidental b. El gobierno de la República Saharaui c. La gente en la República Saharaui d. La ONU y la República Saharaui 3. Párrafo de Cierre 4. Referencias 5. Notas de enseñanza

  11. Total ozone decrease in the Arctic after REP events

    Directory of Open Access Journals (Sweden)

    V. C. Roldugin

    Full Text Available Eight periods of relativistic electron precipitation (REP with electron energies of more than 300 keV are identified from VLF data (10-14 kHz monitored along the Aldra (Norway - Apatity (Kola peninsula radio trace. In these cases, anomalous ionization below 55-50 km occurred without disturbing the higher layers of the ionosphere. The daily total ozone values in Murmansk for six days before and six days after the REP events are compared. In seven of eight events a decrease in the total ozone of about 20 DU is observed. In one event of 25 March, 1986, the mean total ozone value for six days before the REP is bigger than that for six days after, but this a case of an extremely high ozone increase (144 DU during the six days. However, on days 3 and 4 there was a minimum of about 47 DU with regard to REP days, so this case also confirms the concept of the ozone decrease after REP. The difference between mean ozone values for periods six days before and six days after the REPs was found also for 23 points in Arctic on TOMS data. The difference was negative only in Murmansk longitudinal sector. Along the meridian of the trace it was negative at high latitudes in both hemispheres and was near zero at low latitudes.

    Key words: Atmospheric composition and structure (middle atmosphere - composition and chemistry - Meteorology and atmospheric dynamics (polar meteorology

  12. Total ozone decrease in the Arctic after REP events

    Directory of Open Access Journals (Sweden)

    V. C. Roldugin

    2000-03-01

    Full Text Available Eight periods of relativistic electron precipitation (REP with electron energies of more than 300 keV are identified from VLF data (10-14 kHz monitored along the Aldra (Norway - Apatity (Kola peninsula radio trace. In these cases, anomalous ionization below 55-50 km occurred without disturbing the higher layers of the ionosphere. The daily total ozone values in Murmansk for six days before and six days after the REP events are compared. In seven of eight events a decrease in the total ozone of about 20 DU is observed. In one event of 25 March, 1986, the mean total ozone value for six days before the REP is bigger than that for six days after, but this a case of an extremely high ozone increase (144 DU during the six days. However, on days 3 and 4 there was a minimum of about 47 DU with regard to REP days, so this case also confirms the concept of the ozone decrease after REP. The difference between mean ozone values for periods six days before and six days after the REPs was found also for 23 points in Arctic on TOMS data. The difference was negative only in Murmansk longitudinal sector. Along the meridian of the trace it was negative at high latitudes in both hemispheres and was near zero at low latitudes.Key words: Atmospheric composition and structure (middle atmosphere - composition and chemistry - Meteorology and atmospheric dynamics (polar meteorology

  13. RepExplore: addressing technical replicate variance in proteomics and metabolomics data analysis.

    Science.gov (United States)

    Glaab, Enrico; Schneider, Reinhard

    2015-07-01

    High-throughput omics datasets often contain technical replicates included to account for technical sources of noise in the measurement process. Although summarizing these replicate measurements by using robust averages may help to reduce the influence of noise on downstream data analysis, the information on the variance across the replicate measurements is lost in the averaging process and therefore typically disregarded in subsequent statistical analyses.We introduce RepExplore, a web-service dedicated to exploit the information captured in the technical replicate variance to provide more reliable and informative differential expression and abundance statistics for omics datasets. The software builds on previously published statistical methods, which have been applied successfully to biomedical omics data but are difficult to use without prior experience in programming or scripting. RepExplore facilitates the analysis by providing a fully automated data processing and interactive ranking tables, whisker plot, heat map and principal component analysis visualizations to interpret omics data and derived statistics. Freely available at http://www.repexplore.tk enrico.glaab@uni.lu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

  14. Plasmid-Encoded RepA Proteins Specifically Autorepress Individual repABC Operons in the Multipartite Rhizobium leguminosarum bv. trifolii Genome.

    Science.gov (United States)

    Żebracki, Kamil; Koper, Piotr; Marczak, Małgorzata; Skorupska, Anna; Mazur, Andrzej

    2015-01-01

    Rhizobia commonly have very complex genomes with a chromosome and several large plasmids that possess genes belonging to the repABC family. RepA and RepB are members of the ParA and ParB families of partitioning proteins, respectively, whereas RepC is crucial for plasmid replication. In the repABC replicons, partitioning and replication functions are transcriptionally linked resulting in complex regulation of rep gene expression. The genome of R. leguminosarum bv. trifolii TA1 (RtTA1) consists of a chromosome and four plasmids (pRleTA1a-d), equipped with functional repABC genes. In this work, the regulation of transcription of the individual repABC cassettes of the four RtTA1 plasmids was studied. The involvement of the RepA and RepB as well as parS-like centromere sites in this process was depicted, demonstrating some dissimilarity in expression of respective rep regions. RtTA1 repABC genes of individual plasmids formed operons, which were negatively regulated by RepA and RepB. Individual RepA were able to bind to DNA without added nucleotides, but in the presence of ADP, bound specifically to their own operator sequences containing imperfect palindromes, and caused operon autorepression, whereas the addition of ATP stimulated non-specific binding of RepA to DNA. The RepA proteins were able to dimerize/oligomerize: in general dimers formed independently of ATP or ADP, although ATP diminished the concentration of oligomers that were produced. By the comprehensive approach focusing on a set of plasmids instead of individual replicons, the work highlighted subtle differences between the organization and regulation of particular rep operons as well as the structures and specificity of RepA proteins, which contribute to the fine-tuned coexistence of several replicons with similar repABC cassettes in the complex bacterial genome.

  15. A República Mundial de Otfried Höffe

    Directory of Open Access Journals (Sweden)

    Diego Carlos Zanella

    2015-03-01

    Full Text Available Esse texto tem por objetivo apresentar em linhas gerais a proposta de Otfried Höffe sobre a república mundial. Para tanto, iniciar-se-á com o ponto de partida de Höffe, a saber, o fenômeno da globalização, de onde são apontadas as principais atividades e problemas da república mundial. Em seguida, passa-se a analisar os dois níveis da proposta, o nível nacional e o nível internacional ou global da república mundial. Por fim, concluir-se-á com uma tentativa de comparação da proposta de Höffe com a ideia de uma federação de Estados livres apresentada por Immanuel Kant em À paz perpétua.

  16. REP sequences: Mediators of the environmental stress response?

    Science.gov (United States)

    Liang, Wenxing; Deutscher, Murray P

    2016-01-01

    Repetitive Extragenic Palindromic (REP) sequences are highly conserved, structured, 35- to 40-nt elements located at ∼500 positions around the Escherichia coli chromosome. They are found in intergenic regions and are transcribed together with their upstream genes. Although their stable stem-loop structures protect messages against exoribonuclease digestion, their primary function has remained unknown. Recently, we found that about half of all REP sequences have the potential to stall ribosomes immediately upstream of the termination codon, leading to endonucleolytic cleavage of the mRNA, and induction of the trans-translation process. As a consequence, the mRNA and almost completed protein are degraded, and protein production from the affected gene is down-regulated. The process is critically dependent on the location of the REP element, with an effect only if it is within 15 nt of the termination codon. Using nrdAB as a model, we found that its down-regulation is affected by RNA helicases. Elimination of 6 helicases lowered NrdA production further, whereas overexpression of any RNA helicase partially reversed the downregulation. UV stress completely reversed down-regulation of NrdA production. Analysis of genes containing a REP sequence within 15 nt of the termination codon revealed that most, if not all, are up-regulated by environmental stress, as are RNA helicases. Based on these findings, we propose that REP-dependent downregulation serves as a mechanism to allow a rapid response to environmental stresses whereby RNA helicases partially open the REP elements enabling ribosomes to complete translation immediately increasing protein production from the affected genes.

  17. Voto preferencial en la República Dominicana

    Directory of Open Access Journals (Sweden)

    Fausto Marino Mendoza Rodríguez

    2013-01-01

    Full Text Available La República Dominicana tiene establecido como sistema electoral para la elección de diputados el sistema de voto preferencial o preferente cuyo fin primordial es permitirles a los ciudadanos sufragar por el candidato o candidata de su simpatía, de una lista que se les presenta a los electores en una determinada circunscripción. No obstante, el autor apunta que este sistema de elección de diputados, según la experiencia vivida en la República Dominicana, desarrolla luchas encarnizadas a lo interno de los partidos políticos, constituyendo un atentado a la disciplina partidaria.

  18. Images en mouvement stockage, repérage, indexation

    CERN Document Server

    Turner, James

    1998-01-01

    L'avènement puis la fusion des nouveaux modes de communication que sont l'informatique, les télécommunications et l'audiovisuel ont mis à la portée de tous une grande quantité d'images fixes et en mouvement dont la conservation et le repérage risquent de prendre des proportions démesurées. Le présent ouvrage veut offrir aux responsables de collection des repères pour aborder la problématique de l'indexation des images et faciliter l'accès des usagers à ces images.

  19. 3D printing with RepRap cookbook

    CERN Document Server

    Salinas, Richard

    2014-01-01

    A systematic guide consisting of over 100 recipes which focus on helping you understand the process of 3D printing using RepRap machines. The book aims at providing professionals with a series of working recipes to help make their fuzzy notions into real, saleable projects/objects using 3D printing technology. This book is for novice designers and artists who own a RepRap-based 3D printer, have fundamental knowledge of its working, and who desire to gain better mastery of the printing process. For the more experienced user, it will provide a handy visual resource, with side-by-side comparisons

  20. Arduino & RepRap - Creating Wealth by Giving it Away

    DEFF Research Database (Denmark)

    2011-01-01

    , growth in wealth is longevity and prosperity. Is it possible to grow wealth independently of money? This talk will be from Adrian Bowyer - creator of RepRap, the open-source replicating 3D printer - and from David Cuartielles - creator of Arduino, the open-source microcontroller. Both projects have...... founded significant and growing industries - and hence significant and growing wealth - by giving away all the data required to build RepRaps and Arduinos completely free. They have also short-circuited most conventional industrial infrastructure by placing the ability to create wealth directly...

  1. REP1 Modulates Autophagy and Macropinocytosis to Enhance Cancer Cell Survival.

    Science.gov (United States)

    Choi, Jungwon; Kim, Hyena; Bae, Young Ki; Cheong, Heesun

    2017-08-28

    Rab escort protein 1 (REP1), a component of the Rab geranyl-geranyltransferase 2 complex, plays a role in Rab protein recruitment in proper vesicles during vesicle trafficking. In addition to having well-known tissue degenerative phenotypes in the REP1 mutant, REP1 is tightly associated with cancer development and contributes to cell growth and survival. However, the functional mechanism of REP1 in cancer progression is largely uninvestigated. Here, we show that REP1 plays a crucial role in regulating mammalian target of rapamycin (mTOR) signaling and its downstream pathways, as well as autophagy and macropinocytosis, which are essential for cancer cell survival during metabolic stresses including starvation. REP1 small interfering RNA (siRNA) treatment downregulates mTORC1 activity in growing media, but blocks autophagosome formation under nutrient-depleted conditions. In contrast to the mild decrease of lysosomal enzyme activity seen in REP1 depletion, in REP1 knockdown the subcellular localization of lysosomes is altered, and localization of REP1 itself is modulated by intracellular nutrient levels and mTOR activity. Furthermore, REP1 depletion increases macro pinocytosis which may be a feedback mechanism to compensate autophagy inhibition. Concomitant treatment with macropinocytosis inhibitor and REP1siRNAresults in more significant cell death than autophagy blockade with REP1 knockdown. Therefore, REP1-mediated autophagy and lysosomal degradation processes act as novel regulatory mechanisms to support cancer cell survival, which can be further investigated as a potential cancer-targeting pathway.

  2. Characterization of the replication-associated protein (Rep ...

    African Journals Online (AJOL)

    Using GUS and the green fluorescent protein (GFP) as the reporter gene, respectively deletion analysis indicated that 3'-terminus deletion of the 420 nt fragment was not functional, while the 5'-terminus deletions exhibited varying promoter activities. Furthermore, the 227 nt fragment located upstream of the Rep gene ...

  3. Specific functions of the Rep and Rep׳ proteins of porcine circovirus during copy-release and rolling-circle DNA replication.

    Science.gov (United States)

    Cheung, Andrew K

    2015-07-01

    The roles of two porcine circovirus replication initiator proteins, Rep and Rep׳, in generating copy-release and rolling-circle DNA replication intermediates were determined. Rep uses the supercoiled closed-circular genome (ccc) to initiate leading-strand synthesis (identical to copy-release replication) and generates the single-stranded circular (ssc) genome from the displaced DNA strand. In the process, a minus-genome primer (MGP) necessary for complementary-strand synthesis, from ssc to ccc, is synthesized. Rep׳ cleaves the growing nascent-strand to regenerate the parent ccc molecule. In the process, a Rep׳-DNA hybrid containing the right palindromic sequence (at the origin of DNA replication) is generated. Analysis of the virus particle showed that it is composed of four components: ssc, MGP, capsid protein and a novel Rep-related protein (designated Protein-3). Copyright © 2015. Published by Elsevier Inc.

  4. HPV E1 up-regulates replication-related biochemistries of AAV Rep78.

    Science.gov (United States)

    Bandyopadhyay, Sarmistha; Cao, Maohua; Liu, Yong; Hermonat, Paul L

    2010-06-20

    Human papillomavirus type 16 (HPV) E1 protein provides helper function for the adeno-associated virus type 2 (AAV) life cycle. E1 is the replication protein of HPV, analogous to AAV Rep78, but without the endonuclease/covalent attachment activity of Rep78. Previously we have shown that E1 and Rep78 interact in vitro. Here we investigated E1's effects on Rep78 interaction with AAV's inverted terminal repeat (ITR) DNA in vitro, using purified Rep78 and E1 proteins from bacteria. E1 enhanced Rep78-ITR binding, ATPase activity, Rep78-ITR-covalent linkage and Rep78-ITR-endonuclease activity (central to AAV replication). These enhancements occurred in a dose-dependent manner whenever assayed. However, overall Rep78-plus-E1 helicase activity was lower than Rep78's helicase activity. These data suggest that E1's broad-based helper function for the AAV life cycle (AAV DNA, mRNA, and protein levels are up-regulated by E1) is likely through its ability to enhance Rep78's critical replication-required biochemistries on ITR DNA. Published by Elsevier Inc.

  5. Identification of Tilletia species using rep-PCR fingerprinting technique

    Directory of Open Access Journals (Sweden)

    Župunski Vesna

    2011-01-01

    Full Text Available Analyzing 167 non-processed seed samples of wheat, it was found that 145 samples (86.8 % were contaminated with Tilletia species, while 22 (13.2 % samples were not contaminated. By using rep-PCR fingerprinting technique, it was found that DNA isolates of T. tritici originated from Serbian wheat samples had 80 % similarity with positive control for T. tritici. One isolate shared similarity of 60% with T. tritici, T. controversa and T. laevis. It was supposed that this isolate belongs to T. bromi. Isolate of T. laevis shared a similarity of 70 % with isolates of T. tritici and T. controversa, while T. walkeri was more than 10 % similar with T. tritici, T. controversa and T. laevis. Although T. controversa and T. tritici had high percent of genetic similarity, they were clustered separately. Our results suggest that rep-PCR fingerprinting could be a useful tool for monitoring presence of morphologically similar Tilletia species in wheat production areas.

  6. Identification of Tilletia species using rep-PCR fingerprinting technique

    OpenAIRE

    Župunski Vesna; Ignjatović-Micić Dragana; Nikolić Ana; Stanković Slavica; Jevtić Radivoje; Lević Jelena; Ivanović Dragica

    2011-01-01

    Analyzing 167 non-processed seed samples of wheat, it was found that 145 samples (86.8 %) were contaminated with Tilletia species, while 22 (13.2 %) samples were not contaminated. By using rep-PCR fingerprinting technique, it was found that DNA isolates of T. tritici originated from Serbian wheat samples had 80 % similarity with positive control for T. tritici. One isolate shared similarity of 60% with T. tritici, T. controversa and T. laevis. It was suppos...

  7. III República Francesa y Derechos Sociales

    OpenAIRE

    García, Eloy

    2014-01-01

    Lex Social: Revista de derechos sociales, vol.4 , nº1 (2014) p. 1-7 Habitualmente se viene atribuyendo a la República de Weimar y a la Constitución alemana de 11 de agosto de 1919 que la hizo posible, el importante logro de haber impulsado en Europa la emergencia histórica del Estado Social y Democrático de Derecho. Más precisamente se suele localizar de manera concreta su definición conceptual en la obra de Herman Heller que, consciente de la insostenible tensión que en los años veinte y ...

  8. Stress Monitoring of Mulberry Plants by Finding Rep Using Hyperspectral Data

    Science.gov (United States)

    Bhosle, K.; Musande, V.

    2017-05-01

    Stressed on crop can be monitored using different indices. Red Edge position is good estimator for stress monitoring. The red edge position (REP) is strongly correlated with foliar chlorophyll content. Strong chlorophyll absorption causes the abrupt change in the 680-800 nm region of reflectance spectra of green vegetation. The red edge consist the point of maximum slope between red and near-infrared wavelengths. REP can be used to recognize green zone of the observation area. The REP is present in spectra for vegetation recorded by remote sensing methods. REP is clearer and significant in hyper spectral data as hyper spectral consist of more and continuous bands data. In this paper experiments were carried out for mulberry crop using USGS EO-1 Hyperion data. Atmospheric corrected data is used for classification. Classification is carried out on small cluster of 14 field samples. Ground truth is verified and classified by comparing with Hyperion data. REP is different for different stressed condition of crops and shows healthy and diseased crop condition. Nutritional stresses, diseases, drought of plants are detected using REP. Stressed and healthy field of mulberry are estimated by calculating REP using maximum first derivative, linear interpolation, linear extrapolation method. Finally REP is compared using above methods. It is noticeable difference of REP for healthy and stressed crop. The research indicates that overall accuracy using maximum first derivative was 92.85 % and it was more compared to other methods. Linear extrapolation gives less accuracy compared to linear interpolation method.

  9. High-rep-rate Thomson scattering for LHD

    Science.gov (United States)

    den Hartog, D. J.; Borchardt, M. T.; Holly, D. J.; Schmitz, O.; Yasuhara, R.; Yamada, I.; Funaba, H.; Osakabe, M.; Morisaki, T.

    2017-10-01

    A high-rep-rate pulse-burst laser system is being built for the LHD Thomson scattering (TS) diagnostic. This laser will have two operating scenarios, a fast-burst sequence of 15 kHz rep rate for at least 15 ms, and a slow-burst sequence of 1 kHz for at least 50 ms. There will be substantial flexibility in burst sequences for tailoring to experimental requirements. This new laser system will operate alongside the existing lasers in the LHD TS diagnostic, and will use the same beamline. This increase in temporal resolution capability complements the high spatial resolution (144 points) of the LHD TS diagnostic, providing unique measurement capability unmatched on any other fusion experiment. The new pulse-burst laser is a straightforward application of technology developed at UW-Madison, consisting of a Nd:YAG laser head with modular flashlamp drive units and a customized control system. Variable pulse-width drive of the flashlamps is accomplished by IGBT (insulated gate bipolar transistor) switching of electrolytic capacitor banks. Direct control of the laser Pockels cell drive enables optimal pulse energy extraction, producing >1.5 J q-switched pulses with 20 ns FWHM. Burst operation of this laser system will be used to capture fast time evolution of the electron temperature and density profiles during events such as ELMs, RMP perturbations, and various MHD modes. This work is supported by the U. S. Department of Energy and the National Institute for Fusion Science (Japan).

  10. Minister Reps käis välismaal salaja maasikaid korjamas / Kadri Jakobson

    Index Scriptorium Estoniae

    Jakobson, Kadri, 1970-

    2005-01-01

    Haridus- ja teadusminister Mailis Reps töötas 1995-1996 Inglismaal keeleõpingute ajal illegaalselt maasikakorjajana. M. Reps selgitab oma elulookirjelduses esitatud väidet töötamise kohta Cambridge'i ülikooli juures asuvas Trinity kolledzhis. Peaminister Andrus Ansipi kommentaar

  11. AAV-2 Rep78 and HPV-16 E1 interact in vitro, modulating their ATPase activity.

    Science.gov (United States)

    Bandyopadhyay, Sarmistha; Raney, Kevin D; Liu, Yong; Hermonat, Paul L

    2008-01-15

    Adeno-associated virus (AAV) is a nonpathogenic single-stranded human parvovirus which usually requires the presence of a "helper" virus for strong DNA replication. In addition to adeno- and herpes viruses, human papillomavirus (HPV) can serve as an AAV helper. We recently published that HPV type 16 (HPV-16) E1 protein contributes significantly as an individual helper gene for AAV-2 DNA replication and transcription. As Rep78 and E1 are the corresponding DNA helicase/replication proteins of AAV and HPV, respectively, and Rep78 and E1 have a degree of homology, we assayed whether these two proteins interact physically. The full length proteins were purified from bacteria as GST-E1 and MBP-Rep78 and used in five assays to observe Rep78-E1 interactions. All five assays (pull-down, coimmunoprecipitation, enzyme-linked immunosorbent assay (ELISA), chemical cross-linking, and ATPase activity) provided evidence consistent with Rep78-E1 interaction. Most intriguing, an overall decrease in ATPase activity was observed when both proteins were present together. These data strongly suggest that E1 and Rep78 interact and that this interaction modulates at least some of their individual biochemical functions. This study adds to our understanding of AAV-HPV interaction biology, E1's modulation of Rep78 biochemistry, Rep78's modulation of E1 biochemistry and provides initial clues which may lead to the underlying mechanism of HPV E1 helper function for AAV DNA replication.

  12. Automated Production of High Rep Rate Foam Targets

    Science.gov (United States)

    Hall, F.; Spindloe, C.; Haddock, D.; Tolley, M.; Nazarov, W.

    2016-04-01

    Manufacturing low density targets in the numbers needed for high rep rate experiments is highly challenging. This report summarises advances from manual production to semiautomated and the improvements that follow both in terms of production time and target uniformity. The production process is described and shown to be improved by the integration of an xyz robot with dispensing capabilities. Results are obtained from manual and semiautomated production runs and compared. The variance in the foam thickness is reduced significantly which should decrease experimental variation due to target parameters and could allow for whole batches to be characterised by the measurement of a few samples. The work applies to both foil backed and free standing foam targets.

  13. STRESS MONITORING OF MULBERRY PLANTS BY FINDING REP USING HYPERSPECTRAL DATA

    Directory of Open Access Journals (Sweden)

    K. Bhosle

    2017-05-01

    Full Text Available Stressed on crop can be monitored using different indices. Red Edge position is good estimator for stress monitoring. The red edge position (REP is strongly correlated with foliar chlorophyll content. Strong chlorophyll absorption causes the abrupt change in the 680–800 nm region of reflectance spectra of green vegetation. The red edge consist the point of maximum slope between red and near-infrared wavelengths. REP can be used to recognize green zone of the observation area. The REP is present in spectra for vegetation recorded by remote sensing methods. REP is clearer and significant in hyper spectral data as hyper spectral consist of more and continuous bands data. In this paper experiments were carried out for mulberry crop using USGS EO-1 Hyperion data. Atmospheric corrected data is used for classification. Classification is carried out on small cluster of 14 field samples. Ground truth is verified and classified by comparing with Hyperion data. REP is different for different stressed condition of crops and shows healthy and diseased crop condition. Nutritional stresses, diseases, drought of plants are detected using REP. Stressed and healthy field of mulberry are estimated by calculating REP using maximum first derivative, linear interpolation, linear extrapolation method. Finally REP is compared using above methods. It is noticeable difference of REP for healthy and stressed crop. The research indicates that overall accuracy using maximum first derivative was 92.85 % and it was more compared to other methods. Linear extrapolation gives less accuracy compared to linear interpolation method.

  14. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68.

    Directory of Open Access Journals (Sweden)

    Jorge Mansilla-Soto

    2009-07-01

    Full Text Available Rep68 is a multifunctional protein of the adeno-associated virus (AAV, a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific integration of the AAV genome into human chromosome 19. Rep68 is a member of the superfamily 3 (SF3 helicases, along with the well-studied initiator proteins simian virus 40 large T antigen (SV40-LTag and bovine papillomavirus (BPV E1. Structurally, SF3 helicases share two domains, a DNA origin interaction domain (OID and an AAA(+ motor domain. The AAA(+ motor domain is also a structural feature of cellular initiators and it functions as a platform for initiator oligomerization. Here, we studied Rep68 oligomerization in vitro in the presence of different DNA substrates using a variety of biophysical techniques and cryo-EM. We found that a dsDNA region of the AAV origin promotes the formation of a complex containing five Rep68 subunits. Interestingly, non-specific ssDNA promotes the formation of a double-ring Rep68, a known structure formed by the LTag and E1 initiator proteins. The Rep68 ring symmetry is 8-fold, thus differing from the hexameric rings formed by the other SF3 helicases. However, similiar to LTag and E1, Rep68 rings are oriented head-to-head, suggesting that DNA unwinding by the complex proceeds bidirectionally. This novel Rep68 quaternary structure requires both the DNA binding and AAA(+ domains, indicating cooperativity between these regions during oligomerization in vitro. Our study clearly demonstrates that Rep68 can oligomerize through two distinct oligomerization pathways, which depend on both the DNA structure and cooperativity of Rep68 domains. These findings provide insight into the dynamics and oligomeric adaptability of Rep68 and serve as a step towards understanding the role of this multifunctional protein during AAV DNA replication and site-specific integration.

  15. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68.

    Science.gov (United States)

    Mansilla-Soto, Jorge; Yoon-Robarts, Miran; Rice, William J; Arya, Shailee; Escalante, Carlos R; Linden, R Michael

    2009-07-01

    Rep68 is a multifunctional protein of the adeno-associated virus (AAV), a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific integration of the AAV genome into human chromosome 19. Rep68 is a member of the superfamily 3 (SF3) helicases, along with the well-studied initiator proteins simian virus 40 large T antigen (SV40-LTag) and bovine papillomavirus (BPV) E1. Structurally, SF3 helicases share two domains, a DNA origin interaction domain (OID) and an AAA(+) motor domain. The AAA(+) motor domain is also a structural feature of cellular initiators and it functions as a platform for initiator oligomerization. Here, we studied Rep68 oligomerization in vitro in the presence of different DNA substrates using a variety of biophysical techniques and cryo-EM. We found that a dsDNA region of the AAV origin promotes the formation of a complex containing five Rep68 subunits. Interestingly, non-specific ssDNA promotes the formation of a double-ring Rep68, a known structure formed by the LTag and E1 initiator proteins. The Rep68 ring symmetry is 8-fold, thus differing from the hexameric rings formed by the other SF3 helicases. However, similiar to LTag and E1, Rep68 rings are oriented head-to-head, suggesting that DNA unwinding by the complex proceeds bidirectionally. This novel Rep68 quaternary structure requires both the DNA binding and AAA(+) domains, indicating cooperativity between these regions during oligomerization in vitro. Our study clearly demonstrates that Rep68 can oligomerize through two distinct oligomerization pathways, which depend on both the DNA structure and cooperativity of Rep68 domains. These findings provide insight into the dynamics and oligomeric adaptability of Rep68 and serve as a step towards understanding the role of this multifunctional protein during AAV DNA replication and site-specific integration.

  16. Possibilities and limitations of RepRap 3D printers and their use in the market

    OpenAIRE

    Žižka, Ondřej

    2014-01-01

    Theoretical part of the thesis is devoted to the relationship of open source licensing to innovation, rapid prototyping and technologies used for 3D printing. There is also a comparison of selected RepRap printers. The main objective is to explore the possibilities and limitations of RepRap 3D printers while also analyzing their use in the Czech market. The aim of the application part is to test selected RepRap printer and explore the possibilities of 3D printing on these devices. In the last...

  17. Paradoxo e natureza no livro V da República

    Directory of Open Access Journals (Sweden)

    Marcelo P. Marques

    2010-12-01

    Full Text Available O artigo analisa a primeira onda do livro V da República de Platão, levando em conta a oposição entre opinião (dóxa e ciência (epistéme, só formulada ao final da terceira onda. Sócrates problematiza a opinião corrente que aceita a diferença de natureza entre homens e mulheres para avançar a ideia de uma natureza humana comum. É essa tese paradoxal que justifica que possam ter uma mesma educação e que, assim, possam desempenhar as mesmas funções, vindo a ser guardiões e governantes da cidade.The paper analyses the first wave in Plato´s Republic V, taking into account the opposition between opinion (doxa and science (episteme, formulated at the end of the third wave. Socrates questions the current opinion which accepts the difference in nature between men and women in order to propose the idea of a common human nature. It is this paradoxical thesis that justifies the proposal that all should have the same education, thus allowing them to fulfill the same functions and, eventually, to become guardians and rulers in the city.

  18. Hariduspoliitikas ilmnevad üksmeele märgid / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 7. juuni lk. 2, Nädaline 10. juuni lk. 2. Haridusminister Mailis Reps Res Publica ja Isamaaliidu ühisest haridusprogrammist ning juba teostumas hariduspoliitilistest eesmärkidest

  19. Reps sai Narvas tõrjuva vastuvõtu osaliseks / Tanel Mazur

    Index Scriptorium Estoniae

    Mazur, Tanel, 1971-

    2005-01-01

    Selle aasta koolirahu kuulutati välja Narva linnuses, rongkäigus osalesid Narva koolide õpilaste hulgas ka üle 1300 teistest piirkondadest saabunud õpilase. Tervituskõnega esines haridus- ja teadusminister Mailis Reps

  20. The Filament-specific Rep1-1 Repellent of the Phytopathogen Ustilago maydis Forms Functional Surface-active Amyloid-like Fibrils

    NARCIS (Netherlands)

    Teertstra, Wieke R.; van der Velden, Gisela J.; de Jong, Jan F.; Kruijtzer, John A. W.; Liskamp, Rob M. J.; Kroon-Batenburg, Loes M. J.; Muller, Wally H.; Gebbink, Martijn F. B. G.; Wosten, Han A. B.

    2009-01-01

    Repellents of the maize pathogen Ustilago maydis are involved in formation of hydrophobic aerial hyphae and in cellular attachment. These peptides, called Rep1-1 to Rep1-11, are encoded by the rep1 gene and result from cleavage of the precursor protein Rep1 during passage of the secretion pathway.

  1. COMPASS Final Report: Radioisotope Electric Propulsion (REP) Centaur Orbiter New Frontiers Mission

    Science.gov (United States)

    Oleson, Steven R.; McGuire, Melissa L.

    2011-01-01

    Radioisotope Electric Propulsion (REP) has been shown in past studies to enable missions to outer planetary bodies including the orbiting of Centaur asteroids. Key to the feasibility for REP missions are long life, low power electric propulsion (EP) devices, low mass Radioisotope Power System (RPS) and light spacecraft (S/C) components. In order to determine the key parameters for EP devices to perform these REP missions a design study was completed to design an REP S/C to orbit a Centaur in a New Frontiers (NF) cost cap. The design shows that an orbiter using several long lived (approx.200 kg xenon (Xe) throughput), low power (approx.700 W) Hall thrusters teamed with six (150 W each) Advanced Stirling Radioisotope Generators (ASRG) can deliver 60 kg of science instruments to a Centaur in 10 yr within the NF cost cap. Optimal specific impulses (Isp) for the Hall thrusters were found to be around 2000 s with thruster efficiencies over 40 percent. Not only can the REP S/C enable orbiting a Centaur (when compared to an all chemical mission only capable of flybys) but the additional power from the REP system can be used to enhance science and simplify communications. The mission design detailed in this report is a Radioisotope Power System (RPS) powered EP science orbiter to the Centaur Thereus with arrival 10 yr after launch, ending in a 1 yr science mapping mission. Along the trajectory, approximately 1.5 yr into the mission, the REP S/C does a flyby of the Trojan asteroid Tlepolemus. The total (Delta)V of the trajectory is 8.9 km/s. The REP S/C is delivered to orbit on an Atlas 551 class launch vehicle with a Star 48 B solid rocket stage

  2. Adeno-Associated Virus (AAV) Type 5 Rep Protein Cleaves a Unique Terminal Resolution Site Compared with Other AAV Serotypes

    OpenAIRE

    Chiorini, John A.; Afione, Sandra; Kotin, Robert M

    1999-01-01

    Adeno-associated virus (AAV) replication depends on two viral components for replication: the AAV nonstructural proteins (Rep) in trans, and inverted terminal repeat (ITR) sequences in cis. AAV type 5 (AAV5) is a distinct virus compared to the other cloned AAV serotypes. Whereas the Rep proteins and ITRs of other serotypes are interchangeable and can be used to produce recombinant viral particles of a different serotype, AAV5 Rep proteins cannot cross-complement in the packaging of a genome w...

  3. Radioisotope electric propulsion (REP): A near-term approach to nuclear propulsion

    Science.gov (United States)

    Schmidt, George R.; Manzella, David H.; Kamhawi, Hani; Kremic, Tibor; Oleson, Steven R.; Dankanich, John W.; Dudzinski, Leonard A.

    2010-02-01

    Studies over the last decade have shown radioisotope-based nuclear electric propulsion to be enhancing and, in some cases, enabling for many potential robotic science missions. Also known as radioisotope electric propulsion (REP), the technology offers the performance advantages of traditional reactor-powered electric propulsion (i.e., high specific impulse propulsion at large distances from the Sun), but with much smaller, affordable spacecraft. Future use of REP requires development of radioisotope power sources with system specific powers well above that of current systems. The US Department of Energy and NASA have developed an advanced Stirling radioisotope generator (ASRG) engineering unit, which was subjected to rigorous flight qualification-level tests in 2008, and began extended lifetime testing later that year. This advancement, along with recent work on small ion thrusters and life extension technology for Hall thrusters, could enable missions using REP sometime during the next decade.

  4. The role of DSC1 components cdc10+, rep1+ and rep2+ in MCB gene transcription at the mitotic G1-S boundary in fission yeast.

    Science.gov (United States)

    White, S; Khaliq, F; Sotiriou, S; McInerny, C J

    2001-12-01

    In this paper, we describe the transcription profile of a group of genes at the G1-S boundary of fission yeast in synchronously dividing mitotic cells, under a variety of different conditions. This transcription profile is unaffected in cells where either cdc10+ or cdc10-C4 are constitutively overexpressed. In contrast, overexpression of either rep1+ or rep2+ results in constitutive expression of MCB-regulated genes, suggesting that these polypeptides have important regulatory properties in controlling MCB transcription. Finally, we examine the pattern of MCB-regulated transcription in cells where the G1 period is extended. Surprisingly, we find that the wee1-50 mutation causes MCB transcription throughout the cell cycle, whereas cells re-fed after nitrogen starvation have normal expression patterns. The implications of these observations for understanding MCB-regulated transcription are discussed.

  5. Segunda república : relaciones laborales y género

    OpenAIRE

    Giménez Baeza, Estela

    2016-01-01

    La Segunda República española legisló un gran volumen de normas entre las que tuvo un papel importante la reforma del sistema de relaciones laborales y la equiparación de derechos entre mujeres y hombres. Pero pese a la abundante normativa sobre igualdad jurídica y política de ambos sexos en el ámbito laboral, el desarrollo y las prácticas empresariales llevadas a cabo durante la Segunda República no siempre respetaban estos preceptos y como consecuencia, continuaron existiendo diferencias re...

  6. El derecho del trabajo democrático en la República de Weimar

    OpenAIRE

    Gil Albuerquerque, Román de la Trinidad

    2016-01-01

    La tesis "El Derecho del Trabajo democrático en la República de Weimar" es, de una parte, una introducción contextualizadora a la historia político-social, sindical, del Derecho del Trabajo y de la obra de significados juristas demócratas comprometidos con el nacimiento de la nueva disciplina jurídica (y en parte responsables de su constitucionalización) y con su desarrollo en la República de Weimar, así como una consideración transversal y comparativa de varias instituciones fundamentales p...

  7. República Checa: red de bibliotecas públicas de la República Checa: cómo afrontar un cambio necesario

    OpenAIRE

    Romera Colomé, Marta

    2006-01-01

    La publicación recoge información sobre la estructura actual, el funcionamiento y el desarrollo de la red de bibliotecas públicas de la ciudad de Praga, y la evolución de la red de bibliotecas de la República Checa, un proceso de adaptación íntimamente ligado a las transformaciones políticas, territoriales y sociales ocurridas de manera inevitable a partir de 1989.

  8. Modified UMS, Modified SemRep and SemMedDB-UTH | Informatics Technology for Cancer Research (ITCR)

    Science.gov (United States)

    Modified UMLS, modified SemRep and SemMedDB-UTH – these are resources (UMLS, SemMedDB-UT) and tools (SemRep) created and maintained by National Library of Medicine that we have modified for personalized cancer therapy and returned to the NLM.

  9. Overview of RepLab 2014: Author Profiling and Reputation Dimensions for Online Reputation Management

    NARCIS (Netherlands)

    Amigó, E.; Carrillo-de-Albornoz, J.; Chugur, I.; Corujo, A.; Gonzalo, J.; Meij, E.; de Rijke, M.; Spina, D.

    2014-01-01

    This paper describes the organisation and results of RepLab 2014, the third competitive evaluation campaign for Online Reputation Management systems. This year the focus lied on two new tasks: reputation dimensions classification and author profiling, which complement the aspects of reputation

  10. Melanophryniscus stelzneri spegazzinii (Anura: Bufonidae) en la República del Paraguay

    OpenAIRE

    Céspedez, Jorge Abel

    1996-01-01

    República del Paraguay, Dpto. Presidente Hayes, entre el Río Pilcomayo y el Río Confuso (24° 43' S, 58° 37' O). 2 ejemplares adultos, números MACN 07630 y 07631. Colectado por el Sr. Pedro Williams el 5 de mayo de 1940.

  11. 76 FR 61778 - Agency Information Collection (Student Beneficiary Report-REPS (Restored Entitlement Program for...

    Science.gov (United States)

    2011-10-05

    ... collection of information through http://www.Regulations.gov or to VA's OMB Desk Officer, OMB Human Resources... Veterans Affairs, will submit the collection of information abstracted below to the Office of Management... approved school. REPS benefit is paid to children of veterans who died in service or who died as a result...

  12. Birmingham Rep, Youth and Community, and the Products and Possibilities of Precarity

    Science.gov (United States)

    Cochrane, Claire

    2017-01-01

    Birmingham Rep, a leading producing theatre based in the UK's "second city", has historically had a complex relationship with the cultural priorities of its home city. In recent years, Birmingham City Council has faced multiple challenges represented by debt burden, government-imposed cuts in public funding, scandals linked to failing…

  13. 75 FR 78694 - Proposed Residential Exchange Program Settlement Agreement Proceeding (REP-12); Public Hearing...

    Science.gov (United States)

    2010-12-16

    ... submitted material; and a decision by the Administrator based on the record. This REP-12 proceeding is... Administrator adopted the Market-Driven Alternative from the Business Plan EIS. This alternative was selected because, among other reasons, it allows BPA to: (1) Recover costs through rates; (2) competitively market...

  14. 76 FR 33030 - Agency Information Collection Activities (Certification of School Attendance-REPS) Under OMB Review

    Science.gov (United States)

    2011-06-07

    ... AFFAIRS Agency Information Collection Activities (Certification of School Attendance--REPS) Under OMB Review AGENCY: Veterans Benefits Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY... collection of information abstracted below to the Office of Management and Budget (OMB) for review and...

  15. RePS: a sequence assembler that masks exact repeats identified from the shotgun data

    DEFF Research Database (Denmark)

    Wang, Jun; Wong, Gane Ka-Shu; Ni, Peixiang

    2002-01-01

    We describe a sequence assembler, RePS (repeat-masked Phrap with scaffolding), that explicitly identifies exact 20mer repeats from the shotgun data and removes them prior to the assembly. The established software is used to compute meaningful error probabilities for each base. Clone-end-pairing i...

  16. RiskREP: Risk-Based Security Requirements Elicitation and Prioritization (extended version)

    NARCIS (Netherlands)

    Herrmann, Andrea; Morali, A.

    2010-01-01

    Today, companies are required to be in control of the security of their IT assets. This is especially challenging in the presence of limited budgets and conflicting requirements. Here, we present Risk-Based Requirements Elicitation and Prioritization (RiskREP), a method for managing IT security

  17. Alejandro Bunge y el problema de la vivienda obrera en la República Argentina (1910-1915

    Directory of Open Access Journals (Sweden)

    Jorge A. Núñez

    2010-04-01

    Full Text Available Este trabajo pretende indagar, a partir del estudio de la figura del economista Alejandro Bunge, en la problemática de la vivienda obrera en la República Argentina en las primeras décadas de la pasada centuria. Aquí se argumentará que los estudios realizados por Alejandro Bunge como director de la División Estadísticas del Departamento Nacional de Trabajo en el período 1910-1915 contribuyeron de manera notable a la elaboración del proyecto y posterior sanción de la Ley de Casas Baratas para Obreros (n°9677. Palabras claves: Vivienda obrera, Catolicismo Social, Estadísticas _________________ABSTRACT: The aim of this work is to carry out a research on the workers housing in Argentina during the first decades of the past century, based on the research done by the economist Alejandro Bunge. The studies carried out by Alejandro Bunge, Director of Statistics Division of the National Labour Department during 1910-1915, highly contributed to the project and further sanction of the "Cheap Houses for Workers Law" (Nbr. 9677. KeyWords: Workers Housing, Social Catholicism, Statistics

  18. Genetic Diversity and Evidence for Transmission of Streptococcus mutans by DiversiLab rep-PCR.

    Science.gov (United States)

    Momeni, Stephanie S; Whiddon, Jennifer; Cheon, Kyounga; Ghazal, Tariq; Moser, Stephen A; Childers, Noel K

    2016-09-01

    This two-part study investigated the genetic diversity and transmission of Streptococcus mutans using the DiversiLab repetitive extragenic palindromic PCR (rep-PCR) approach. For children with S. mutans and participating household members, analysis for evidence of unrelated child-to-child as well as intra-familial transmission was evaluated based on commonality of genotypes. A total of 169 index children and 425 household family members from Uniontown, Alabama were evaluated for genetic diversity using rep-PCR. Thirty-four unique rep-PCR genotypes were observed for 13,906 S. mutans isolates. For transmission, 117 child and household isolates were evaluated for shared genotype (by child and by genotype cases, multiple matches possible for each child). Overall, children had 1-9 genotypes and those with multiple genotypes were 2.3 times more likely to have caries experience (decayed, missing and filled teeth/surfaces>0). Only 28% of children shared all genotypes within the household, while 72% had at least 1 genotype not shared with anyone in the household. Children had genotype(s) not shared with any household members in 157 cases. In 158 cases children and household members shared a genotype in which 55% (87/158 cases) were shared with more than one family member. Children most frequently shared genotypes with their mothers (54%; 85/158), siblings (46%; 72/158) and cousins (23%; 37/158). A reference library for S. mutans for epidemiological surveillance using the DiversiLab rep-PCR approach is detailed. The genetic diversity of S. mutans in this population demonstrated frequent commonality of genotypes. Evidence for both child-to-child and intra-familial transmission of S. mutans was observed by rep-PCR. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Cancer Statistics

    Science.gov (United States)

    ... What Is Cancer? Cancer Statistics Cancer Disparities Cancer Statistics Cancer has a major impact on society in ... success of efforts to control and manage cancer. Statistics at a Glance: The Burden of Cancer in ...

  20. Caregiving Statistics

    Science.gov (United States)

    ... Coping with Alzheimer’s COPD Caregiving Take Care! Caregiver Statistics Statistics on Family Caregivers and Family Caregiving Caregiving Population ... Health Care Caregiver Self-Awareness State by State Statistics Caregiving Population The value of the services family ...

  1. Anaplasmosis: Statistics and Epidemiology

    Science.gov (United States)

    ... cases reported 2002 0.6% case fatality 2003 3.0% case fatality 2004 0.3% case fatality 2005 ... Wkly Rep(58)2009,1033 CDC. Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain spotted fever, ...

  2. Análisis de la relación comercial entre la República de Colombia y la República de Costa Rica

    OpenAIRE

    Romero Escobar, Juán Sebastián; Bermudez Monroy, María Gabriela

    2012-01-01

    Dadas las relaciones de cooperación internacional que presentan las Repúblicas de Colombia y Costa Rica, que se evidencia en los fuertes vínculos comerciales existentes entre las dos naciones, Proexport por medio de su oficina comercial en Costa Rica, ha mantenido al tanto la situación en la que se desenvuelve la alianza comercial entre Colombia y Costa Rica. Él último de estos informes, demuestra la potencialidad de Costa Rica como un mercado para los bienes colombianos y una posibilidad par...

  3. Análisis de la relación comercial entre la República de Colombia y la República de Corea

    OpenAIRE

    Andrade Tovar, Viviana; Pérez Álvarez, Laura Marcela

    2012-01-01

    Dadas las relaciones de cooperación internacional que presentan las Repúblicas de Colombia y Corea que se evidencia en los fuertes vínculos comerciales existentes entre las dos naciones y aún más en la negociación de un TLC desde el 2009 y gracias al buen clima económico que presenta en la actualidad Colombia, surge este proyecto de investigación con el objetivo de analizar las relaciones bilaterales y contribuir al desarrollo de la economía emergente que presenta el país. Para ello, en pr...

  4. RepSeq – A database of amino acid repeats present in lower eukaryotic pathogens

    Directory of Open Access Journals (Sweden)

    Smith Deborah F

    2007-04-01

    Full Text Available Abstract Background Amino acid repeat-containing proteins have a broad range of functions and their identification is of relevance to many experimental biologists. In human-infective protozoan parasites (such as the Kinetoplastid and Plasmodium species, they are implicated in immune evasion and have been shown to influence virulence and pathogenicity. RepSeq http://repseq.gugbe.com is a new database of amino acid repeat-containing proteins found in lower eukaryotic pathogens. The RepSeq database is accessed via a web-based application which also provides links to related online tools and databases for further analyses. Results The RepSeq algorithm typically identifies more than 98% of repeat-containing proteins and is capable of identifying both perfect and mismatch repeats. The proportion of proteins that contain repeat elements varies greatly between different families and even species (3–35% of the total protein content. The most common motif type is the Sequence Repeat Region (SRR – a repeated motif containing multiple different amino acid types. Proteins containing Single Amino Acid Repeats (SAARs and Di-Peptide Repeats (DPRs typically account for 0.5–1.0% of the total protein number. Notable exceptions are P. falciparum and D. discoideum, in which 33.67% and 34.28% respectively of the predicted proteomes consist of repeat-containing proteins. These numbers are due to large insertions of low complexity single and multi-codon repeat regions. Conclusion The RepSeq database provides a repository for repeat-containing proteins found in parasitic protozoa. The database allows for both individual and cross-species proteome analyses and also allows users to upload sequences of interest for analysis by the RepSeq algorithm. Identification of repeat-containing proteins provides researchers with a defined subset of proteins which can be analysed by expression profiling and functional characterisation, thereby facilitating study of pathogenicity

  5. ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS

    Directory of Open Access Journals (Sweden)

    Alves-Ferreira Marcelo

    2008-09-01

    Full Text Available Abstract Background Genome survey sequences (GSS offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive regions of the genome. A more precise estimation of the nature, quantity and variability of repetitive sequences very early in a genome sequencing project is of considerable importance, as such data strongly influence the estimation of genome coverage, library quality and progress in scaffold construction. Also, the elimination of repetitive sequences from the initial assembly process is important to avoid errors and unnecessary complexity. Repetitive sequences are also of interest in a variety of other studies, for instance as molecular markers. Results We designed and implemented a straightforward pipeline called ReRep, which combines bioinformatics tools for identifying repetitive structures in a GSS dataset. In a case study, we first applied the pipeline to a set of 970 GSSs, sequenced in our laboratory from the human pathogen Leishmania braziliensis, the causative agent of leishmaniosis, an important public health problem in Brazil. We also verified the applicability of ReRep to new sequencing technologies using a set of 454-reads of an Escheria coli. The behaviour of several parameters in the algorithm is evaluated and suggestions are made for tuning of the analysis. Conclusion The ReRep approach for identification of repetitive elements in GSS datasets proved to be straightforward and efficient. Several potential repetitive sequences were found in a L. braziliensis GSS dataset generated in our laboratory, and further validated by the analysis of a more complete genomic dataset from the EMBL and Sanger Centre databases. ReRep also identified most of the E. coli K12 repeats prior to assembly in an example dataset obtained by automated sequencing using 454 technology. The parameters controlling the algorithm behaved consistently and may be tuned to the properties

  6. Reflexões sobre a República, em Machado de Assis

    Directory of Open Access Journals (Sweden)

    Maria Antonieta Pereira

    2000-03-01

    Full Text Available Tendo presenciado, ao final do século XIX, eventos decisivos da Históriado Brasil, Machado de Assis, em vários de seus textos ficcionais, aborda importantes aspectos relativos ao surgimento de tendências republicanas no país. As contradições geradas pela nova organização social, discutidas no romance Esaú e Jacó e nos contos "Teoria do medalhão"e "A sereníssima República", são objeto de nossa análise que buscainvestigar a presença de conceitos relativos à República e à nacionalidadeno Brasil, nos conflitos culturais e ambivalências lingüísticas abordadospelo autor enquanto análise do cotidiano nacional.

  7. A república e o sonho The republic and its dream

    Directory of Open Access Journals (Sweden)

    Maria Tereza Chaves de Mello

    2011-06-01

    Full Text Available O desencanto com a República brasileira tem sido tema de reflexões desde os seus momentos iniciais. Buscando os conteúdos concretos dos sonhos republicanos na década de 1880 e na Primeira República vamos achar uma importante defasagem entre eles não exatamente em função do marco cronológico, mas do grupo social que, respectivamente, os acalentou.The disillusion with the Brazilian Republic since its first days has been a topic of academician reflexions. Examinating the concrete contents of the 1880`s and the First Republic republican dreams we will find a substantive difference between them. To be exact, this difference must not be related to the chronological demarcation but to the social group that embraced each of them.

  8. práctica del turismo rural en la República de Cuba

    Directory of Open Access Journals (Sweden)

    Isis Alejandra Camargo Toribio

    2005-01-01

    Full Text Available El presente trabajo incluye parte de los resultados que se obtuvieron en la tesis doctoral “Aportaciones metodológicas para la implementación del turismo rural en la República de Cuba. Estudio de caso: zona turística de Viñales” (Camargo, 2003. El objetivo principal de este artículo es conocer las preferencias de los clientes internacionales para la práctica del turismo rural, modalidad que no está establecida de forma consciente en la República de Cuba y que, de acuerdo con el potencial naturalcultural existente, tiene amplias posibilidades para su introducción. Con este fin se aplica una encuesta donde los viajeros evalúan, en una escala ascendente, la importancia que le conceden a un conjunto de elementos para la práctica de la modalidad rural

  9. Characterisation of Rep-encoding components associated with banana bunchy top nanovirus in Vietnam.

    Science.gov (United States)

    Bell, K E; Dale, J L; Ha, C V; Vu, M T; Revill, P A

    2002-04-01

    We have analysed the sequence variability of the banana bunchy top nanovirus (BBTV) DNA-1 sequence from 17 isolates collected throughout Vietnam, and showed that the level of DNA-1 sequence variation within Vietnam was approximately double that previously reported for Asian BBTV isolates. Furthermore, the sequences separated into two geographical subgroups that generally correlated to the northern or southern regions of Vietnam. We have also characterised an additional putative Rep-encoding component associated with some BBTV isolates from Vietnam. This component, which we have named BBTV-S3, shared 47%, 69%, 56% and 65% nucleotide sequence identity with the previously reported Rep-encoding components BBTV DNA-1, S1, S2 and Y1 respectively.

  10. Tratamiento tributario actual del comercio electrónico en la República Argentina

    OpenAIRE

    Martínez Giribone, María Silvana

    2010-01-01

    Tratamiento tributario actual del comercio electrónico en la República Argentina. PROBLEMA: ¿Constituye la legislación tributaria argentina aplicada a operaciones comerciales tradicionales un marco legal acorde para gravar operaciones de comercio electrónico? OBJETIVOS DE LA INVESTIGACION OBJETIVO GENERAL Analizar la aplicación de la legislación tributaria argentina para operaciones de comercio tradicionales en el comercio electrónico. OBJETIVOS ESPECIFICOS Ana...

  11. Vanguardismo y problemática del film alemán de la República de Weimar

    OpenAIRE

    Sánchez-Biosca, Vicente

    1985-01-01

    El presente artículo trata de examinar las aproximaciones historiográficas realizadas al cine producido en la República de Weimar, desde el llamado expresionismo hasta las corrientes realistas, pasando por el Kammerspielfilm.

  12. 78 FR 53774 - Guide for the Evaluation of Alert and Notification Systems for Nuclear Power Plants, FEMA-REP-10...

    Science.gov (United States)

    2013-08-30

    ... not available when FEMA REP-10 was first developed, such as smartphones and social media. Removes... that State, local, Tribal, and utility offsite plans and preparedness are adequate to protect public...

  13. Reps võib kõrvale heita kümme miljonit maksnud õppekava / Dagne Hanschmidt

    Index Scriptorium Estoniae

    Hanschmidt, Dagne

    2005-01-01

    TÜ õppekavade arenduskeskus ja AS Bit koostavad mõlemad riikliku õppekava, lähtudes erinevatest põhimõttest. Haridus- ja teadusminister Mailis Reps ei ole avaldanud, kumba õppekava varianti ta eelistab

  14. A Comparison of Molecular Typing Methods Applied to Enterobacter cloacae complex: hsp60 Sequencing, Rep-PCR, and MLST

    Directory of Open Access Journals (Sweden)

    Roberto Viau

    2017-02-01

    Full Text Available Molecular typing using repetitive sequenced-based PCR (rep-PCR and hsp60 sequencing were applied to a collection of diverse Enterobacter cloacae complex isolates. To determine the most practical method for reference laboratories, we analyzed 71 E. cloacae complex isolates from sporadic and outbreak occurrences originating from 4 geographic areas. While rep-PCR was more discriminating, hsp60 sequencing provided a broader and a more objective geographical tracking method similar to multilocus sequence typing (MLST. In addition, we suggest that MLST may have higher discriminative power compared to hsp60 sequencing, although rep-PCR remains the most discriminative method for local outbreak investigations. In addition, rep-PCR can be an effective and inexpensive method for local outbreak investigation.

  15. Data on publications, structural analyses, and queries used to build and utilize the AlloRep database

    Directory of Open Access Journals (Sweden)

    Filipa L. Sousa

    2016-09-01

    Full Text Available The AlloRep database (www.AlloRep.org (Sousa et al., 2016 [1] compiles extensive sequence, mutagenesis, and structural information for the LacI/GalR family of transcription regulators. Sequence alignments are presented for >3000 proteins in 45 paralog subfamilies and as a subsampled alignment of the whole family. Phenotypic and biochemical data on almost 6000 mutants have been compiled from an exhaustive search of the literature; citations for these data are included herein. These data include information about oligomerization state, stability, DNA binding and allosteric regulation. Protein structural data for 65 proteins are presented as easily-accessible, residue-contact networks. Finally, this article includes example queries to enable the use of the AlloRep database. See the related article, “AlloRep: a repository of sequence, structural and mutagenesis data for the LacI/GalR transcription regulators” (Sousa et al., 2016 [1].

  16. RepPop: a database for repetitive elements in Populus trichocarpa

    Directory of Open Access Journals (Sweden)

    Xu Ying

    2009-01-01

    Full Text Available Abstract Background Populus trichocarpa is the first tree genome to be completed, and its whole genome is currently being assembled. No functional annotation about the repetitive elements in the Populus trichocarpa genome is currently available. Results We predicted 9,623 repetitive elements in the Populus trichocarpa genome, and assigned functions to 3,075 of them (31.95%. The 9,623 repetitive elements cover ~40% of the current (partially assembled genome. Among the 9,623 repetitive elements, 668 have copies only in the contigs that have not been assigned to one of the 19 chromosome while the rest all have copies in the partially assembled chromosomes. Conclusion All the predicted data are organized into an easy-to-use web-browsable database, RepPop. Various search capabilities are provided against the RepPop database. A Wiki system has been set up to facilitate functional annotation and curation of the repetitive elements by a community rather than just the database developer. The database RepPop will facilitate the assembling and functional characterization of the Populus trichocarpa genome.

  17. Rep-PCR-based typing as a tool for tracking of MRSA infection origin

    Directory of Open Access Journals (Sweden)

    Ivan Manga

    2012-01-01

    Full Text Available A performance of rep-PCR fingerprinting method with the (GTG5 primer was explored in order to evaluate its practical application for confirmation the source of human staphylococci infection. A laboratory worker daily working with the MRSA and Staphylococcus aureus strains has been tested positively for MRSA nosocomial infection. The collection of nine MRSA strains held in the laboratory has been typed with the rep-PCR method. Analysis of the fingerprints with the unweighted pair-group method using arithmetic averages (UPGMA clustering method revealed presence of six strain clusters with similarity lower than 85%. The fingerprint of MRSA strain infecting the human differed significantly from remaining fingerprints. This provided clear evidence that MRSA strain infecting the personal did not come from the laboratory strains collection. Our experimental results showed rep-PCR with the (GTG5 primer as an effective tool applicable for differentiation of individual S. aureus strains. However, the reproducibility and discrimination power of the method depended on strict observance of the optimal PCR time and temperature profile and PCR composition as well.

  18. La república en general y en el constitucionalismo polaco

    Directory of Open Access Journals (Sweden)

    Marguerita Masternak-Kubiak

    2006-01-01

    Full Text Available Los profesores constitucionalistas universitarios de Wroclaw tratan de escudriñar la noción de república en Polonia. En este orden de ideas, comienzan su trabajo por el repaso de los textos clásicos y modernos sobre este concepto, para luego presentar dos experiencias y modelos republicanos (estadounidense y francés. Terminado esto, desentrañan la versión polaca de esta forma de gobierno. Llegan a la conclusión de que rzeczpospolita –nombre y práctica de la república en su país– no corresponde a varias características del régimen en cuestión. Lo más peculiar de la variante patria de la república consiste en que ésta puede compaginarse incluso con la forma monárquica del Estado. Por eso, según los autores –independientemente de la profundidad de posibles futuros cambios en el sistema político polaco–, su patria conservará siempre su tradicional nombre rzeczpospolita.

  19. Descriptive statistics.

    Science.gov (United States)

    Shi, Runhua; McLarty, Jerry W

    2009-10-01

    In this article, we introduced basic concepts of statistics, type of distributions, and descriptive statistics. A few examples were also provided. The basic concepts presented herein are only a fraction of the concepts related to descriptive statistics. Also, there are many commonly used distributions not presented herein, such as Poisson distributions for rare events and exponential distributions, F distributions, and logistic distributions. More information can be found in many statistics books and publications.

  20. Integration Preferences of Wildtype AAV-2 for Consensus Rep-Binding Sites at Numerous Loci in the Human Genome

    Science.gov (United States)

    Hüser, Daniela; Gogol-Döring, Andreas; Lutter, Timo; Weger, Stefan; Winter, Kerstin; Hammer, Eva-Maria; Cathomen, Toni; Reinert, Knut; Heilbronn, Regine

    2010-01-01

    Adeno-associated virus type 2 (AAV) is known to establish latency by preferential integration in human chromosome 19q13.42. The AAV non-structural protein Rep appears to target a site called AAVS1 by simultaneously binding to Rep-binding sites (RBS) present on the AAV genome and within AAVS1. In the absence of Rep, as is the case with AAV vectors, chromosomal integration is rare and random. For a genome-wide survey of wildtype AAV integration a linker-selection-mediated (LSM)-PCR strategy was designed to retrieve AAV-chromosomal junctions. DNA sequence determination revealed wildtype AAV integration sites scattered over the entire human genome. The bioinformatic analysis of these integration sites compared to those of rep-deficient AAV vectors revealed a highly significant overrepresentation of integration events near to consensus RBS. Integration hotspots included AAVS1 with 10% of total events. Novel hotspots near consensus RBS were identified on chromosome 5p13.3 denoted AAVS2 and on chromsome 3p24.3 denoted AAVS3. AAVS2 displayed seven independent junctions clustered within only 14 bp of a consensus RBS which proved to bind Rep in vitro similar to the RBS in AAVS3. Expression of Rep in the presence of rep-deficient AAV vectors shifted targeting preferences from random integration back to the neighbourhood of consensus RBS at hotspots and numerous additional sites in the human genome. In summary, targeted AAV integration is not as specific for AAVS1 as previously assumed. Rather, Rep targets AAV to integrate into open chromatin regions in the reach of various, consensus RBS homologues in the human genome. PMID:20628575

  1. Integration preferences of wildtype AAV-2 for consensus rep-binding sites at numerous loci in the human genome.

    Directory of Open Access Journals (Sweden)

    Daniela Hüser

    Full Text Available Adeno-associated virus type 2 (AAV is known to establish latency by preferential integration in human chromosome 19q13.42. The AAV non-structural protein Rep appears to target a site called AAVS1 by simultaneously binding to Rep-binding sites (RBS present on the AAV genome and within AAVS1. In the absence of Rep, as is the case with AAV vectors, chromosomal integration is rare and random. For a genome-wide survey of wildtype AAV integration a linker-selection-mediated (LSM-PCR strategy was designed to retrieve AAV-chromosomal junctions. DNA sequence determination revealed wildtype AAV integration sites scattered over the entire human genome. The bioinformatic analysis of these integration sites compared to those of rep-deficient AAV vectors revealed a highly significant overrepresentation of integration events near to consensus RBS. Integration hotspots included AAVS1 with 10% of total events. Novel hotspots near consensus RBS were identified on chromosome 5p13.3 denoted AAVS2 and on chromsome 3p24.3 denoted AAVS3. AAVS2 displayed seven independent junctions clustered within only 14 bp of a consensus RBS which proved to bind Rep in vitro similar to the RBS in AAVS3. Expression of Rep in the presence of rep-deficient AAV vectors shifted targeting preferences from random integration back to the neighbourhood of consensus RBS at hotspots and numerous additional sites in the human genome. In summary, targeted AAV integration is not as specific for AAVS1 as previously assumed. Rather, Rep targets AAV to integrate into open chromatin regions in the reach of various, consensus RBS homologues in the human genome.

  2. Integration preferences of wildtype AAV-2 for consensus rep-binding sites at numerous loci in the human genome.

    Science.gov (United States)

    Hüser, Daniela; Gogol-Döring, Andreas; Lutter, Timo; Weger, Stefan; Winter, Kerstin; Hammer, Eva-Maria; Cathomen, Toni; Reinert, Knut; Heilbronn, Regine

    2010-07-08

    Adeno-associated virus type 2 (AAV) is known to establish latency by preferential integration in human chromosome 19q13.42. The AAV non-structural protein Rep appears to target a site called AAVS1 by simultaneously binding to Rep-binding sites (RBS) present on the AAV genome and within AAVS1. In the absence of Rep, as is the case with AAV vectors, chromosomal integration is rare and random. For a genome-wide survey of wildtype AAV integration a linker-selection-mediated (LSM)-PCR strategy was designed to retrieve AAV-chromosomal junctions. DNA sequence determination revealed wildtype AAV integration sites scattered over the entire human genome. The bioinformatic analysis of these integration sites compared to those of rep-deficient AAV vectors revealed a highly significant overrepresentation of integration events near to consensus RBS. Integration hotspots included AAVS1 with 10% of total events. Novel hotspots near consensus RBS were identified on chromosome 5p13.3 denoted AAVS2 and on chromsome 3p24.3 denoted AAVS3. AAVS2 displayed seven independent junctions clustered within only 14 bp of a consensus RBS which proved to bind Rep in vitro similar to the RBS in AAVS3. Expression of Rep in the presence of rep-deficient AAV vectors shifted targeting preferences from random integration back to the neighbourhood of consensus RBS at hotspots and numerous additional sites in the human genome. In summary, targeted AAV integration is not as specific for AAVS1 as previously assumed. Rather, Rep targets AAV to integrate into open chromatin regions in the reach of various, consensus RBS homologues in the human genome.

  3. Binding of sulphonated indigo derivatives to RepA-WH1 inhibits DNA-induced protein amyloidogenesis

    Science.gov (United States)

    Gasset-Rosa, Fátima; Maté, María Jesús; Dávila-Fajardo, Cristina; Bravo, Jerónimo; Giraldo, Rafael

    2008-01-01

    The quest for inducers and inhibitors of protein amyloidogenesis is of utmost interest, since they are key tools to understand the molecular bases of proteinopathies such as Alzheimer, Parkinson, Huntington and Creutzfeldt–Jakob diseases. It is also expected that such molecules could lead to valid therapeutic agents. In common with the mammalian prion protein (PrP), the N-terminal Winged-Helix (WH1) domain of the pPS10 plasmid replication protein (RepA) assembles in vitro into a variety of amyloid nanostructures upon binding to different specific dsDNA sequences. Here we show that di- (S2) and tetra-sulphonated (S4) derivatives of indigo stain dock at the DNA recognition interface in the RepA-WH1 dimer. They compete binding of RepA to its natural target dsDNA repeats, found at the repA operator and at the origin of replication of the plasmid. Calorimetry points to the existence of a major site, with micromolar affinity, for S4-indigo in RepA-WH1 dimers. As revealed by electron microscopy, in the presence of inducer dsDNA, both S2/S4 stains inhibit the assembly of RepA-WH1 into fibres. These results validate the concept that DNA can promote protein assembly into amyloids and reveal that the binding sites of effector molecules can be targeted to inhibit amyloidogenesis. PMID:18285361

  4. The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization.

    Science.gov (United States)

    Maggin, Jenna E; James, Jeffrey A; Chappie, Joshua S; Dyda, Fred; Hickman, Alison Burgess

    2012-03-01

    The adeno-associated virus (AAV) genome encodes four Rep proteins, all of which contain an SF3 helicase domain. The larger Rep proteins, Rep78 and Rep68, are required for viral replication, whereas Rep40 and Rep52 are needed to package AAV genomes into preformed capsids; these smaller proteins are missing the site-specific DNA-binding and endonuclease domain found in Rep68/78. Other viral SF3 helicases, such as the simian virus 40 large T antigen and the papillomavirus E1 protein, are active as hexameric assemblies. However, Rep40 and Rep52 have not been observed to form stable oligomers on their own or with DNA, suggesting that important determinants of helicase multimerization lie outside the helicase domain. Here, we report that when the 23-residue linker that connects the endonuclease and helicase domains is appended to the adeno-associated virus type 5 (AAV5) helicase domain, the resulting protein forms discrete complexes on DNA consistent with single or double hexamers. The formation of these complexes does not require the Rep binding site sequence, nor is it nucleotide dependent. These complexes have stimulated ATPase and helicase activities relative to the helicase domain alone, indicating that they are catalytically relevant, a result supported by negative-stain electron microscopy images of hexameric rings. Similarly, the addition of the linker region to the AAV5 Rep endonuclease domain also confers on it the ability to bind and multimerize on nonspecific double-stranded DNA. We conclude that the linker is likely a key contributor to Rep68/78 DNA-dependent oligomerization and may play an important role in mediating Rep68/78's conversion from site-specific DNA binding to nonspecific DNA unwinding.

  5. RepB proteins of the multipartite Rhizobium leguminosarum bv. trifolii genome discriminate between centromere-like parS sequences for plasmid segregational stability.

    Science.gov (United States)

    Koper, Piotr; Żebracki, Kamil; Marczak, Małgorzata; Skorupska, Anna; Mazur, Andrzej

    2016-11-01

    The plasmids of the Rhizobiaceae family members and other Alphaproteobacteria are usually large, low copy-number and contain all elements necessary for active segregation and replication located in one operon comprising repABC genes. The genome of Rhizobium leguminosarum bv. trifolii TA1 (RtTA1) consists of a chromosome and four plasmids (pRleTA1a-d) with repABC operons. In this work, centromere-binding RepB proteins of four RtTA1 plasmids were studied. Stability assays of the truncated derivatives of repABC cassettes demonstrated that RepA, RepB proteins and parS-like elements constituted plasmid partitioning systems, while RepC were sufficient for their replication. Individual RepB proteins bound specifically to centromere-like parS elements of the parental plasmids, which was crucial step toward the proper segregation of plasmids into daughter cells. RtTA1 RepB proteins formed dimers and oligomers in the solution. The C-terminal part of RepB was responsible for dimerization, while the domain engaged in parS binding was located in the middle of the protein. It was concluded that the specific interaction between individual RepB proteins and their target sequences together with the substantial diversity of the Rep proteins and parS originating from different plasmids strongly contributed to the coexistence of several plasmids equipped with similar repABC cassettes in the multipartite bacterial genome. © 2016 John Wiley & Sons Ltd.

  6. Statistical physics

    CERN Document Server

    Sadovskii, Michael V

    2012-01-01

    This volume provides a compact presentation of modern statistical physics at an advanced level. Beginning with questions on the foundations of statistical mechanics all important aspects of statistical physics are included, such as applications to ideal gases, the theory of quantum liquids and superconductivity and the modern theory of critical phenomena. Beyond that attention is given to new approaches, such as quantum field theory methods and non-equilibrium problems.

  7. Harmonic statistics

    Energy Technology Data Exchange (ETDEWEB)

    Eliazar, Iddo, E-mail: eliazar@post.tau.ac.il

    2017-05-15

    The exponential, the normal, and the Poisson statistical laws are of major importance due to their universality. Harmonic statistics are as universal as the three aforementioned laws, but yet they fall short in their ‘public relations’ for the following reason: the full scope of harmonic statistics cannot be described in terms of a statistical law. In this paper we describe harmonic statistics, in their full scope, via an object termed harmonic Poisson process: a Poisson process, over the positive half-line, with a harmonic intensity. The paper reviews the harmonic Poisson process, investigates its properties, and presents the connections of this object to an assortment of topics: uniform statistics, scale invariance, random multiplicative perturbations, Pareto and inverse-Pareto statistics, exponential growth and exponential decay, power-law renormalization, convergence and domains of attraction, the Langevin equation, diffusions, Benford’s law, and 1/f noise. - Highlights: • Harmonic statistics are described and reviewed in detail. • Connections to various statistical laws are established. • Connections to perturbation, renormalization and dynamics are established.

  8. Statistical distributions

    CERN Document Server

    Forbes, Catherine; Hastings, Nicholas; Peacock, Brian J.

    2010-01-01

    A new edition of the trusted guide on commonly used statistical distributions Fully updated to reflect the latest developments on the topic, Statistical Distributions, Fourth Edition continues to serve as an authoritative guide on the application of statistical methods to research across various disciplines. The book provides a concise presentation of popular statistical distributions along with the necessary knowledge for their successful use in data modeling and analysis. Following a basic introduction, forty popular distributions are outlined in individual chapters that are complete with re

  9. Statistical methods

    CERN Document Server

    Szulc, Stefan

    1965-01-01

    Statistical Methods provides a discussion of the principles of the organization and technique of research, with emphasis on its application to the problems in social statistics. This book discusses branch statistics, which aims to develop practical ways of collecting and processing numerical data and to adapt general statistical methods to the objectives in a given field.Organized into five parts encompassing 22 chapters, this book begins with an overview of how to organize the collection of such information on individual units, primarily as accomplished by government agencies. This text then

  10. Statistical optics

    CERN Document Server

    Goodman, Joseph W

    2015-01-01

    This book discusses statistical methods that are useful for treating problems in modern optics, and the application of these methods to solving a variety of such problems This book covers a variety of statistical problems in optics, including both theory and applications.  The text covers the necessary background in statistics, statistical properties of light waves of various types, the theory of partial coherence and its applications, imaging with partially coherent light, atmospheric degradations of images, and noise limitations in the detection of light. New topics have been introduced i

  11. Scan Statistics

    CERN Document Server

    Glaz, Joseph

    2009-01-01

    Suitable for graduate students and researchers in applied probability and statistics, as well as for scientists in biology, computer science, pharmaceutical science and medicine, this title brings together a collection of chapters illustrating the depth and diversity of theory, methods and applications in the area of scan statistics.

  12. Practical Statistics

    CERN Document Server

    Lyons, L.

    2016-01-01

    Accelerators and detectors are expensive, both in terms of money and human effort. It is thus important to invest effort in performing a good statistical anal- ysis of the data, in order to extract the best information from it. This series of five lectures deals with practical aspects of statistical issues that arise in typical High Energy Physics analyses.

  13. Species-specific repetitive extragenic palindromic (REP) sequences in Pseudomonas putida

    Science.gov (United States)

    Aranda-Olmedo, Isabel; Tobes, Raquel; Manzanera, Maximino; Ramos, Juan L.; Marqués, Silvia

    2002-01-01

    Pseudomonas putida KT2440 is a soil bacterium that effectively colonises the roots of many plants and degrades a variety of toxic aromatic compounds. Its genome has recently been sequenced. We describe that a 35 bp sequence with the structure of an imperfect palindrome, originally found repeated three times downstream of the rpoH gene terminator, is detected more than 800 times in the chromosome of this strain. The structure of this DNA segment is analogous to that of the so-called enterobacteriaceae repetitive extragenic palindromic (REP) sequences, although its sequence is different. Computer-assisted analysis of the presence and distribution of this repeated sequence in the P.putida chromosome revealed that in at least 80% of the cases the sequence is extragenic, and in 82% of the cases the distance of this extragenic element to the end of one of the neighbouring genes was <100 bp. This 35 bp element can be found either as a single element, as pairs of elements, or sometimes forming clusters of up to five elements in which they alternate orientation. PCR scanning of chromosomes from different isolates of Pseudomonas sp. strains using oligonucleotides complementary to the most conserved region of this sequence shows that it is only present in isolates of the species P.putida. For this reason we suggest that the P.putida 35 bp element is a distinctive REP sequence in P.putida. This is the first time that REP sequences have been described and characterised in a group of non-enterobacteriaceae. PMID:11937637

  14. Antibiotic Susceptibility and Molecular Typing by REP-PCR among Acinetobacter baumannii Isolates

    Directory of Open Access Journals (Sweden)

    Delsuz Rezaee

    2014-04-01

    Full Text Available Background & Objectives : Acinetobacter baumannii is an opportunistic Gram-negative pathogen with increasing relevance in a variety of hospital-acquired infections especially among intensive care unit patients. A. baumannii is mostly a cause of septicemia, pneumonia and urinary tract infection following hospitalization of patients. In this study antibiotic susceptibility pattern of A.baumannii isolates and molecular typing among isolates resistant by REP-PCR were determined.   Methods : During study, the A. baumannii, were isolated from hospitals in Tehran. The isolates were identified using standard biochemical tests and antibiotic susceptibility was determined by the disk diffusion method. Extraction of DNA and molecular typing of isolates performed using CTAB method and REP-PCR, respectively.   Results : In this study 75 A. baumannii isolates separated from patients with an average age of 51 ± 18.45 years . The highest resistance rate was against azteronam (97%, ceftazidim (93%, cefepime (93%, piperacillin-tazobactam (93%, ciprofloxacin (93% and ticarcillin (93% while the lowest resistance rate was against tigecycline (n= 51, 68%, followed by tobramycin (n=24, 32%, ampicillin-sulbactam (n=21, 28%, amikacin (n=16, 21%, and carbapenems (n=11, 15%. The REP-PCR in resistant of A. baumannii isolates showed that the genotypes of A, B and C are the predominant genotypes in the resistant antibiotics.   Conclusion: This study showed a high percentage of resistance to antimicrobial agents among genotypes A, B, and C of the A. baumannii isolates therefore strategies to control the spread of A. baumannii isolates must be designed and evaluated.

  15. COMPASS Final Report: Saturn Moons Orbiter Using Radioisotope Electric Propulsion (REP): Flagship Class Mission

    Science.gov (United States)

    Oleson, Steven R.; McGuire, Melissa L.

    2011-01-01

    The COllaborative Modeling and Parametric Assessment of Space Systems (COMPASS) team was approached by the NASA Glenn Research Center (GRC) In-Space Project to perform a design session to develop Radioisotope Electric Propulsion (REP) Spacecraft Conceptual Designs (with cost, risk, and reliability) for missions of three different classes: New Frontier s Class Centaur Orbiter (with Trojan flyby), Flagship, and Discovery. The designs will allow trading of current and future propulsion systems. The results will directly support technology development decisions. The results of the Flagship mission design are reported in this document

  16. O Governo Provisório da República e a Cultura em Portugal

    OpenAIRE

    Fraga, Luís Alves de

    2014-01-01

    Procura-se, neste texto, relacionar a influência da corrente literária Realista-Naturalista com as medidas revolucionárias adoptadas pelo Governo Provisório da República, em Portugal, nos poucos meses de 1910 e no ano de 1911, evidenciando que o desmantelar da influência da Igreja Católica na sociedade nacional e a necessidade de se desenvolverem, entre nós, os diferentes níveis de ensino estavam intimamente ligados, formando as bases de uma revolução cultural que se pretendia levar o mais lo...

  17. La República de los historiadores del Paraguay posbélico

    OpenAIRE

    Telesca, Ignacio

    2015-01-01

    En ocasión del bicentenario de la adopción de la República como sistema de gobierno, e independiente tanto de España como de Buenos Aires, este artículo reflexiona sobre como los historiadores paraguayos de fines de siglo XIX reflexionaron sobre el tema, relacionándolo con la adopción de un nuevo sistema de gobierno con la constitución de 1870 (calco de la argentina). Fil: Telesca, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET ...

  18. El cine y la República de Weimar: la nueva objetividad

    OpenAIRE

    García Rábano, Ángela Pino

    2017-01-01

    La República de Weimar nos deja apreciar una visión de un país que aún se encuentra en una situación muy tensa, tras la derrota de la Primera Guerra Mundial, enfrentándose ahora a un futuro incierto con las tropas nazis, pero con una sociedad que está dispuesta a resurgir. Como no podría ser de otra manera, el Arte contribuye a plasmar todo ese remolino de sensaciones The Weimar Republic let us appreciate the point of view of a country that is still in a complicated situation, after being ...

  19. AAV2 X increases AAV6 rep/cap-driven rAAV production

    OpenAIRE

    Cao, M.; Chiriva-Internati, M.; Hermonat, P L

    2015-01-01

    We have recently identified a new gene, involved in DNA replication, at the far 3′ end of the adeno-associated virus type 2 (AAV2) genome. The AAV type 6 (AAV6) genome has a disrupted X open reading frame (ORF) whose two halves, when combined, have full-length homology and comparable size to AAV2 X. Hypothesizing that AAV6 X is inactive, we assessed if AAV2 X augments recombinant (r)AAV2 DNA replication and virion production, but with rep and cap trans-functions of AAV6. Using AAV2 X expressi...

  20. Lightweight Autonomous Underwater Vehicles (AUVs) performing coastal survey operations in REP 10A

    Science.gov (United States)

    Incze, Michael L.

    2011-11-01

    Lightweight Autonomous Underwater Vehicles (AUVs) were developed for Naval Special Warfare (NSW) Group 4 search and survey missions from a commercial AUV baseline (Iver 2) through integration of commercial off-the-shelf (COTS) hardware components, and through software development for enhanced on-board Command and Control functions. The development period was 1 year under a project sponsored by the Office of Naval Research TechSolutions Program Office. Hardware integration was completed by the commercial AUV vendor, OceanServer Technology, Inc., and software development was conducted by the Naval Undersea Warfare Center, Naval Oceanographic Office, and U MASS Dartmouth, with support from hardware and software application providers (YSI, Inc., Imagenex Technology Corp., and CARIS). At the conclusion of the integration and development period, an at-sea performance evaluation was scheduled for the Lightweight NSW AUVs with NSWG-4 personnel. The venue for this evaluation was the NATO exercise Recognized Environmental Picture 10A (REP 10A), hosted by Marinha Portuguesa, and coordinated by the Faculdade de Engenharia-Universidade do Porto. REP 10A offered an opportunity to evaluate the performance of the new AUVs and to explore the Concept of Operations (CONOPS) for employing them in military survey operations in shallow coastal waters. Shore- and ship-launched scenarios with launch/recovery by a single operator in a one-to-many coordinated survey, on-scene data product generation and visualization, data push to Reach Back Cells for product integration and enhancement, and survey optimization to streamline survey effort and timelines were included in the CONOPS review. Opportunities to explore employment of hybrid AUV fleets in Combined Force scenarios were also utilized. The Naval Undersea Warfare Center, Marinha Portuguesa, the Faculdade de Engenharia-Universidade do Porto, and OceanServer Technology, Inc., were the primary participants bringing in-water resources to

  1. Estado de los diarios digitales en República Dominicana : enero-julio, 2014

    OpenAIRE

    Reynoso Matos, Marggi Mayrobi

    2014-01-01

    La presente investigación analiza la situación de los medios digitales en la República Dominicana, con el objetivo de realizar una serie de recomendaciones para la mejora de estos medios online emergentes. Se persigue cambiar la percepción que los medios digitales tienen que estar escudados en grandes cabeceras, estos pueden ser autónomos y completamente digitales sin la necesidad de una versión impresa del mismo. También hay que considerar que el Ciberperiodista debe contar con ciertas destr...

  2. Ayatollah Khomeini: o pai da República Islâmica

    OpenAIRE

    Damásio, Ana

    2007-01-01

    Conhecido pelo seu turbante negro e ar austero, o ayatollah Khomeini é umas das figuras mais importantes do século XX. As suas ideias representam um ponto de viragem para a comunidade muçulmana ( umma ), que assistiu à construção da primeira República Islâmica. Curiosamente, esta fez-se por via do xiismo, ramo minoritário do islão, com Khomeini como motor deste regime teocrático.

  3. Carreiras políticas e nepotismo na Terceira República francesa (1871-1940)

    OpenAIRE

    Niess,Alexandre

    2012-01-01

    Ainda que possa parecer improvável em um regime baseado no sufrágio universal masculino, as conexões familiares e o nepotismo cumpriram um papel extremamente importante na democracia representativa na Terceira República Francesa (1870-1940). Na verdade, essas práticas continuam importantes em algumas partes da esfera política até hoje. Este artigo examina detalhadamente as conexões e as práticas políticas no departamento de Marne, um espaço político onde vários tipos diferentes de conexões po...

  4. Ser socio de la red de bibliotecas del Banco de la República

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    2002-05-01

    Full Text Available La Biblioteca Luis Ángel Arango inició en 1996, un programa de socios de la biblioteca con el fin de brindarles una mayor facilidad en la consulta de su material bibliográfico y de ofrecerles la información de todas las actividades culturales que se realizan en su sede. A partir de 2003 se encuentran en la red todas las áreas culturales del Banco de la República del país: Armenia, Manizales, Pereira, Medellín, Buenaventura, Quibdó, Ipiales, Pasto, Popayán; Cali, Leticia, San Andrés.

  5. Semiconductor statistics

    CERN Document Server

    Blakemore, J S

    1962-01-01

    Semiconductor Statistics presents statistics aimed at complementing existing books on the relationships between carrier densities and transport effects. The book is divided into two parts. Part I provides introductory material on the electron theory of solids, and then discusses carrier statistics for semiconductors in thermal equilibrium. Of course a solid cannot be in true thermodynamic equilibrium if any electrical current is passed; but when currents are reasonably small the distribution function is but little perturbed, and the carrier distribution for such a """"quasi-equilibrium"""" co

  6. Statistics Clinic

    Science.gov (United States)

    Feiveson, Alan H.; Foy, Millennia; Ploutz-Snyder, Robert; Fiedler, James

    2014-01-01

    Do you have elevated p-values? Is the data analysis process getting you down? Do you experience anxiety when you need to respond to criticism of statistical methods in your manuscript? You may be suffering from Insufficient Statistical Support Syndrome (ISSS). For symptomatic relief of ISSS, come for a free consultation with JSC biostatisticians at our help desk during the poster sessions at the HRP Investigators Workshop. Get answers to common questions about sample size, missing data, multiple testing, when to trust the results of your analyses and more. Side effects may include sudden loss of statistics anxiety, improved interpretation of your data, and increased confidence in your results.

  7. Development of low-cost open source 3D gel printer "RepRap SWIM-ER"

    Science.gov (United States)

    Sato, Kei; Basher, Samiul; Ota, Takafumi; Tase, Taishi; Takamatsu, Kyuichiro; Saito, Azusa; Khosla, Ajit; Kawakami, Masaru; Furuawa, Hidemitsu

    2017-04-01

    Gels are soft and wet materials having low friction, good biocompatibility, and material permeability. It is expected that gel materials will be used as new kinds of industrial materials in the engineering and medical applications. But it cannot build a complicated shape. Soft & Wet Matter Engineering Laboratory developed a 3D gel Printer "SWIM-ER", has enabled modeling of complex shapes of the gel. However, this is expensive. Therefore not all of the gel researchers and the companies have such a device. To solve this problem, we manufacture a low-cost open-source 3D gel printer "RepRap SWIM-ER" from the RepRap. We made the components required to manufacture the "RepRap SWIM-ER" from the 3D printer and chose a light source. In addition, we produced the P-DN gel for RepRap SWIM-ER and conducted the molding test to confirm whether RepRap SWIM-ER can used it.

  8. diffReps: detecting differential chromatin modification sites from ChIP-seq data with biological replicates.

    Directory of Open Access Journals (Sweden)

    Li Shen

    Full Text Available ChIP-seq is increasingly being used for genome-wide profiling of histone modification marks. It is of particular importance to compare ChIP-seq data of two different conditions, such as disease vs. control, and identify regions that show differences in ChIP enrichment. We have developed a powerful and easy to use program, called diffReps, to detect those differential sites from ChIP-seq data, with or without biological replicates. In addition, we have developed two useful tools for ChIP-seq analysis in the diffReps package: one for the annotation of the differential sites and the other for finding chromatin modification "hotspots". diffReps is developed in PERL programming language and runs on all platforms as a command line script. We tested diffReps on two different datasets. One is the comparison of H3K4me3 between two human cell lines from the ENCODE project. The other is the comparison of H3K9me3 in a discrete region of mouse brain between cocaine- and saline-treated conditions. The results indicated that diffReps is a highly sensitive program in detecting differential sites from ChIP-seq data.

  9. CMS Statistics

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CMS Center for Strategic Planning produces an annual CMS Statistics reference booklet that provides a quick reference for summary information about health...

  10. WPRDC Statistics

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Data about the usage of the WPRDC site and its various datasets, obtained by combining Google Analytics statistics with information from the WPRDC's data portal.

  11. Accident Statistics

    Data.gov (United States)

    Department of Homeland Security — Accident statistics available on the Coast Guard’s website by state, year, and one variable to obtain tables and/or graphs. Data from reports has been loaded for...

  12. Image Statistics

    Energy Technology Data Exchange (ETDEWEB)

    Wendelberger, Laura Jean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-08

    In large datasets, it is time consuming or even impossible to pick out interesting images. Our proposed solution is to find statistics to quantify the information in each image and use those to identify and pick out images of interest.

  13. Multiparametric statistics

    CERN Document Server

    Serdobolskii, Vadim Ivanovich

    2007-01-01

    This monograph presents mathematical theory of statistical models described by the essentially large number of unknown parameters, comparable with sample size but can also be much larger. In this meaning, the proposed theory can be called "essentially multiparametric". It is developed on the basis of the Kolmogorov asymptotic approach in which sample size increases along with the number of unknown parameters.This theory opens a way for solution of central problems of multivariate statistics, which up until now have not been solved. Traditional statistical methods based on the idea of an infinite sampling often break down in the solution of real problems, and, dependent on data, can be inefficient, unstable and even not applicable. In this situation, practical statisticians are forced to use various heuristic methods in the hope the will find a satisfactory solution.Mathematical theory developed in this book presents a regular technique for implementing new, more efficient versions of statistical procedures. ...

  14. Trichomoniasis Statistics

    Science.gov (United States)

    ... Search Form Controls Cancel Submit Search the CDC Trichomoniasis Note: Javascript is disabled or is not supported ... Twitter STD on Facebook Sexually Transmitted Diseases (STDs) Trichomoniasis Statistics Recommend on Facebook Tweet Share Compartir In ...

  15. Reversible Statistics

    DEFF Research Database (Denmark)

    Tryggestad, Kjell

    2004-01-01

    The study aims is to describe how the inclusion and exclusion of materials and calculative devices construct the boundaries and distinctions between statistical facts and artifacts in economics. My methodological approach is inspired by John Graunt's (1667) Political arithmetic and more recent work...... within constructivism and the field of Science and Technology Studies (STS). The result of this approach is here termed reversible statistics, reconstructing the findings of a statistical study within economics in three different ways. It is argued that all three accounts are quite normal, albeit...... in different ways. The presence and absence of diverse materials, both natural and political, is what distinguishes them from each other. Arguments are presented for a more symmetric relation between the scientific statistical text and the reader. I will argue that a more symmetric relation can be achieved...

  16. Vital statistics

    CERN Document Server

    MacKenzie, Dana

    2004-01-01

    The drawbacks of using 19th-century mathematics in physics and astronomy are illustrated. To continue with the expansion of the knowledge about the cosmos, the scientists will have to come in terms with modern statistics. Some researchers have deliberately started importing techniques that are used in medical research. However, the physicists need to identify the brand of statistics that will be suitable for them, and make a choice between the Bayesian and the frequentists approach. (Edited abstract).

  17. Realidades de la independencia del Banco de la República Realities of the independence of the Banco de la República

    Directory of Open Access Journals (Sweden)

    Kalmanovitz Salomón

    1997-12-01

    Full Text Available La autonomía del banco central Colombiano es parte del proceso político que buscaba reducir el exagerado centralismo colombiano. Sin embargo el poder central no fue limitado en grado suficiente por la Constitución del 1991, como muestra el hecho de que el Ministro de Hacienda es el Presidente de la Junta Directiva del Banco de la República. Esto no sucede en ningun banco independiente del mundo por que los objetivos del gobierno son distintos a los del Banco Central y el Ministerio de Finanzas podría desviar al Banco de sus objetivos antiinflacionarios fundamentales. En Colombia, el gobierno no sólo participa en la Junta para acomodar sus múltiples objetivos sino también hace opocisión pública a la política monetaria y así la desacredita. El articulo plantea que el principio de no reelección hace que el horizonte de tiempo sea muy corto para que el gobierno coseche los frutos de una política de estabilización. El gobierno tiende a gastar en exceso para mejorar su imagen pública y el desajuste lo tiene que enfrentar el gobierno siguiente. De modo que la coordinación entre el Banco Central y el gobierno se torna muy conflictiva.The autonomy of the Central Bank of Colombia is part of a political process which seeks to reduce Colombia' s exaggerated centralismo However, central power was not limited to a sufficient degree by the Constitution of 1991, as demonstrated by the fact that the Minister of Finance is the President of the Board of Directors of the Banco de la República. This does not happen in any independent bank in the world, because the objectives of the government are different from those of the central bank, and the Minister of Finance could divert the Bank away from its fundamental anti-inflationary objectives. This article proposes that the principle of no reelection makes the time horizon very short for the government to reap the fruits of a stabilization policy. The government tends to spend in excess in order to

  18. Efficient, high rep rate, large-bore kinetically enhanced copper vapor laser with low (thermal assembly.

    Science.gov (United States)

    Singh, Bijendra; Subramaniam, V V; Daultabad, S R; Chakraborty, Ashim

    2009-10-01

    Large-bore kinetically enhanced copper vapor laser (CVL) based on new thermal assembly consisting of different density zones of insulation material (alumina fiber) around the discharge tube is demonstrated for the first time with efficiency eta > or = 1% at extremely low specific input power (SIP) of insulation material, efficiency of approximately 1.2% was achieved at lowest SIP of approximately 0.75 kW/l. Net reduction in the input power of approximately 1 kW was observed on using this thermal assembly as compared to nonprofiled thermal assembly. These results show significant improvement (25%-30%) at low input requirements of the laser on using new thermal assembly around the discharge tube with overall electro-optical efficiency eta > or = 1%. Maximum laser power achieved from the laser was approximately 78 W at approximately 9.8 kHz rep rate with efficiency of approximately 1.4%. This large-bore CVL is also capable of operating efficiently (eta approximately 1%) at high rep rate of -17 kHz with maximum laser power of approximately 50 W. Performance of the laser under various operating conditions is also presented in this short paper.

  19. Averróis e a República de Platão

    Directory of Open Access Journals (Sweden)

    Pereira, Rosalie Helena de Souza

    2007-01-01

    Full Text Available Sobre República é o único comentário de uma obra de Platão deixado por Averróis, o comentador por antonomásia, diga-se de Aristóteles. Embora se tenha perdido o original árabe, a teles. Embora se tenha perdido o original árabe, a posteridade recebeu uma versão hebraíca e duas latinas. O comentário (ou paráfrase a República de Platão pode ser considerado uma obra original - divida em três livros - já que apenas um terço dela corresponde ao texto platônico. Além de apresentar conceitos aristotélicos retirados da Ética Nicomaquéia e de obras políticas de Al-Farabi, Averróis apresenta reflexões próprias e faz críticas à sociedade em que vive

  20. Contradições da República romana: o surgimento do poder pessoal

    Directory of Open Access Journals (Sweden)

    Alex Aparecido da Costa

    2014-01-01

    Full Text Available A partir da segunda Guerra Púnica, ocorrida em fins do século III a. C., a sociedade romana passou por um processo de transformação que enfraqueceria as instituições republicanas controladas pelos grupos oligárquicos de Roma. A República, criada por volta do ano 509 a. C. substituira a realeza e pretendera evitar o retorno de uma figura monárquica que ultrapasse o poder dos nobres patrícios. Para isso foram criados cargos políticos e militares colegiados com duração de um ano, denominados magistraturas, como forma de diluir o poder entre seus membros. Todavia, a expansão imperialista de Roma pelo Mediterrâneo levou ao limite esses instrumentos conservadores. A partir de então, baseados nas tradições romanas e na necessidade de adequar as instituições à realidade imperial, políticos e militares iniciaram uma marcha em busca de poder pessoal, pelo qual reivindicaram para si a responsabilidade de restaurar a República, mas com o qual, contraditoriamente, apressaram seu fim.

  1. Generation of RGB-D data for SLAM using robotic framework V-REP

    Science.gov (United States)

    Gritsenko, Pavel S.; Gritsenko, Igor S.; Seidakhmet, Askar Zh.; Abduraimov, Azizbek E.

    2017-09-01

    In this article, we will present a methodology to debug RGB-D SLAM systems as well as to generate testing data. We have created a model of a laboratory with an area of 250 m2 (25 × 10) with set of objects of different type. V-REP Microsoft Kinect sensor simulation model was used as a basis for robot vision system. Motion path of the sensor model has multiple loops. We have written a program in V-Rep native language Lua to record data array from the Microsoft Kinect sensor model. The array includes both RGB and Depth streams with full resolution (640 × 480) for every 10 cm of the path. The simulated path has absolute accuracy, since it is a simulation, and is represented by an array of transformation matrices (4 × 4). The length of the data array is 1000 steps or 100 m. The path simulates frequently occurring cases in SLAM, including loops. It is worth noting that the path was modeled for a mobile robot and it is represented by a 2D path parallel to the floor at a height of 40 cm.

  2. Estado actual de la odontopediatría en la República Mexicana

    Directory of Open Access Journals (Sweden)

    Enrique E .-Huitzil-Muñóz

    2012-02-01

    Full Text Available La odontología pediátrica satisface un propósito muy especial con respecto de las especialidades odontológicas orientada a la prevención y curación de las enfermedades del sistema estomatognático durante la infancia y considerada como una especialidad muy completa y relativamente nueva se realiza una revisión acerca de la historia de la odontología pedíatrica en el mundo y en especial en México, recopilando información importante acerca de las instituciones universitarias que cuentan en su curricula con la especialidad, certificación y zonas de ubicación en la República Mexicana. Conclusiones: De acuerdo a las regiones de la República Mexicana en las que se encuentran ubicados los diversos posgrados, se concluye que de un total de 30 universidades que cuentan con la especialidad o maestría en odontopediatría, existen 7 en la denominada región centro y golfo y 6 en la región México D.F., estos datos concuerdan con el elevado número de habitantes que habitan esas regiones y que necesitan atención odontopediátrica cubriendo así la alta demanda del servicio por parte de los odontólogos posgraduados egresados.

  3. Identification of new isolates of Bacillus thuringiensis using rep-PCR products and delta-endotoxin electron microscopy

    Directory of Open Access Journals (Sweden)

    A.S.G. Lima

    2002-01-01

    Full Text Available PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic and ERIC (Enterobacterial Repetitive Intergenic Consensus sequences (rep-PCR found within the genome of the bacterium Bacillus thuringiensis, with the purpose to analyze the genetic similarities among 56 subspecies samples and 95 field isolates. The PCR products were analyzed by EB-AGE (ethidium bromide-agarose electrophoresis and then submitted to banding comparisons, based on the Phyllip software algorithm. When the banding similarities were considered for comparison purposes among all the strains, the phylogenic tree patterns varied according to the rep-PCR primers considered, but, from a broader point of view, the ERIC sequences produced better results, which, together with electron microscopy analysis of the released parasporal bodies and colony morphology characteristics, allowed to detect two possible new subspecies of B. thuringiensis.

  4. Identification of new isolates of Bacillus thuringiensis using rep-PCR products and d-endotoxin electron microscopy

    Directory of Open Access Journals (Sweden)

    Lima A.S.G.

    2002-01-01

    Full Text Available PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic and ERIC (Enterobacterial Repetitive Intergenic Consensus sequences (rep-PCR found within the genome of the bacterium Bacillus thuringiensis, with the purpose to analyze the genetic similarities among 56 subspecies samples and 95 field isolates. The PCR products were analyzed by EB-AGE (ethidium bromide-agarose electrophoresis and then submitted to banding comparisons, based on the Phyllip software algorithm. When the banding similarities were considered for comparison purposes among all the strains, the phylogenic tree patterns varied according to the rep-PCR primers considered, but, from a broader point of view, the ERIC sequences produced better results, which, together with electron microscopy analysis of the released parasporal bodies and colony morphology characteristics, allowed to detect two possible new subspecies of B. thuringiensis.

  5. Statistical mechanics

    CERN Document Server

    Jana, Madhusudan

    2015-01-01

    Statistical mechanics is self sufficient, written in a lucid manner, keeping in mind the exam system of the universities. Need of study this subject and its relation to Thermodynamics is discussed in detail. Starting from Liouville theorem gradually, the Statistical Mechanics is developed thoroughly. All three types of Statistical distribution functions are derived separately with their periphery of applications and limitations. Non-interacting ideal Bose gas and Fermi gas are discussed thoroughly. Properties of Liquid He-II and the corresponding models have been depicted. White dwarfs and condensed matter physics, transport phenomenon - thermal and electrical conductivity, Hall effect, Magneto resistance, viscosity, diffusion, etc. are discussed. Basic understanding of Ising model is given to explain the phase transition. The book ends with a detailed coverage to the method of ensembles (namely Microcanonical, canonical and grand canonical) and their applications. Various numerical and conceptual problems ar...

  6. Statistical physics

    CERN Document Server

    Guénault, Tony

    2007-01-01

    In this revised and enlarged second edition of an established text Tony Guénault provides a clear and refreshingly readable introduction to statistical physics, an essential component of any first degree in physics. The treatment itself is self-contained and concentrates on an understanding of the physical ideas, without requiring a high level of mathematical sophistication. A straightforward quantum approach to statistical averaging is adopted from the outset (easier, the author believes, than the classical approach). The initial part of the book is geared towards explaining the equilibrium properties of a simple isolated assembly of particles. Thus, several important topics, for example an ideal spin-½ solid, can be discussed at an early stage. The treatment of gases gives full coverage to Maxwell-Boltzmann, Fermi-Dirac and Bose-Einstein statistics. Towards the end of the book the student is introduced to a wider viewpoint and new chapters are included on chemical thermodynamics, interactions in, for exam...

  7. Statistical mechanics

    CERN Document Server

    Schwabl, Franz

    2006-01-01

    The completely revised new edition of the classical book on Statistical Mechanics covers the basic concepts of equilibrium and non-equilibrium statistical physics. In addition to a deductive approach to equilibrium statistics and thermodynamics based on a single hypothesis - the form of the microcanonical density matrix - this book treats the most important elements of non-equilibrium phenomena. Intermediate calculations are presented in complete detail. Problems at the end of each chapter help students to consolidate their understanding of the material. Beyond the fundamentals, this text demonstrates the breadth of the field and its great variety of applications. Modern areas such as renormalization group theory, percolation, stochastic equations of motion and their applications to critical dynamics, kinetic theories, as well as fundamental considerations of irreversibility, are discussed. The text will be useful for advanced students of physics and other natural sciences; a basic knowledge of quantum mechan...

  8. Statistical mechanics

    CERN Document Server

    Davidson, Norman

    2003-01-01

    Clear and readable, this fine text assists students in achieving a grasp of the techniques and limitations of statistical mechanics. The treatment follows a logical progression from elementary to advanced theories, with careful attention to detail and mathematical development, and is sufficiently rigorous for introductory or intermediate graduate courses.Beginning with a study of the statistical mechanics of ideal gases and other systems of non-interacting particles, the text develops the theory in detail and applies it to the study of chemical equilibrium and the calculation of the thermody

  9. AP statistics

    CERN Document Server

    Levine-Wissing, Robin

    2012-01-01

    All Access for the AP® Statistics Exam Book + Web + Mobile Everything you need to prepare for the Advanced Placement® exam, in a study system built around you! There are many different ways to prepare for an Advanced Placement® exam. What's best for you depends on how much time you have to study and how comfortable you are with the subject matter. To score your highest, you need a system that can be customized to fit you: your schedule, your learning style, and your current level of knowledge. This book, and the online tools that come with it, will help you personalize your AP® Statistics prep

  10. Statistical inference

    CERN Document Server

    Rohatgi, Vijay K

    2003-01-01

    Unified treatment of probability and statistics examines and analyzes the relationship between the two fields, exploring inferential issues. Numerous problems, examples, and diagrams--some with solutions--plus clear-cut, highlighted summaries of results. Advanced undergraduate to graduate level. Contents: 1. Introduction. 2. Probability Model. 3. Probability Distributions. 4. Introduction to Statistical Inference. 5. More on Mathematical Expectation. 6. Some Discrete Models. 7. Some Continuous Models. 8. Functions of Random Variables and Random Vectors. 9. Large-Sample Theory. 10. General Meth

  11. Desplazando al Rey en la escuela de la nueva nación mexicana: "el catecismo de República"

    Directory of Open Access Journals (Sweden)

    María Adelina ARREDONDO LÓPEZ

    2010-03-01

    Full Text Available RESUMEN: Este artículo estudia cómo un texto escolar, como el catecismo político de la nueva República de México, contribuye a desplazar de la escuela primaria la presencia colonial española, representada en el Rey, por nuevas imágenes de las instituciones de la naciente República de México. ABSTRACT: This paper studie how a textbook, the politic catechism of Mexican Republic, contribute to suplant the Spanish King instead the new images of the recent Mexican Republic during the emancipation process.

  12. Iberia : capital federal de la IIª República Española (Un proyecto de Rubio i Tuduri

    Directory of Open Access Journals (Sweden)

    Carlos Sambricio

    1996-01-01

    Full Text Available A los pocos meses de proclamarse, en 1931, la II República Española, Nicolás Rubio i Tuduri presentaba —en el marco de la Exposición organizada por la Asociación de Arquitectos de Cataluña, celebrada en la barcelonesa Galería Maragall— una propuesta un tanto sorprendente: el proyecto de una nueva Capital Federal de la República Española que él denominaba Iberia.

  13. Desplazando al Rey en la escuela de la nueva nación mexicana: "el catecismo de República"

    OpenAIRE

    María Adelina ARREDONDO LÓPEZ

    2010-01-01

    RESUMEN: Este artículo estudia cómo un texto escolar, como el catecismo político de la nueva República de México, contribuye a desplazar de la escuela primaria la presencia colonial española, representada en el Rey, por nuevas imágenes de las instituciones de la naciente República de México. ABSTRACT: This paper studie how a textbook, the politic catechism of Mexican Republic, contribute to suplant the Spanish King instead the new images of the recent Mexican Republic during the emancipation ...

  14. Em busca do despertar: o fortalecimento da sociedade civil angolana após a Segunda República

    Directory of Open Access Journals (Sweden)

    Rodrigo de Souza Pain

    2006-01-01

    passagem da Primeira República, caracterizada por um Estado de Partido Único, por uma economia planificada e inspirada nos ideais marxistas e leninistas; para a Segunda República, ou seja, para uma economia de mercado, multipartidária, explicitando as adversidades advindas das diversas realidades sociais, políticas e culturais do espaço territorial angolano resultante do processo de colonização, para a formação e consolidação da democracia e da sociedade civil em Angola.

  15. Statistical Mechancis

    CERN Document Server

    Gallavotti, Giovanni

    2011-01-01

    C. Cercignani: A sketch of the theory of the Boltzmann equation.- O.E. Lanford: Qualitative and statistical theory of dissipative systems.- E.H. Lieb: many particle Coulomb systems.- B. Tirozzi: Report on renormalization group.- A. Wehrl: Basic properties of entropy in quantum mechanics.

  16. Statistical Computing

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 10. Statistical Computing - Understanding Randomness and Random Numbers. Sudhakar Kunte. Series Article Volume 4 Issue 10 October 1999 pp 16-21. Fulltext. Click here to view fulltext PDF. Permanent link:

  17. The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins.

    Directory of Open Access Journals (Sweden)

    Louise Madsen

    Full Text Available The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors. In addition, p97 plays a central role in degradation of misfolded secretory proteins via the ER-associated degradation pathway. This functional diversity of p97 depends on its association with various cofactors, and to further our understanding of p97 function it is important that these cofactors are identified and analyzed. Here, we isolate and characterize the human protein named Rep8 or Ubxd6 as a new cofactor of p97. Mouse Rep8 is highly tissue-specific and abundant in gonads. In testes, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Rep8 associates directly with p97 via its UBX domain. We show that Rep8 is a transmembrane protein that localizes to the ER membrane with its UBX domain facing the cytoplasm. Knock-down of Rep8 expression in human cells leads to a decreased association of p97 with the ER membrane and concomitantly a retarded degradation of misfolded ER-derived proteasome substrates. Thus, Rep8 tethers p97 to the ER membrane for efficient ER-associated degradation.

  18. [Descriptive statistics].

    Science.gov (United States)

    Rendón-Macías, Mario Enrique; Villasís-Keever, Miguel Ángel; Miranda-Novales, María Guadalupe

    2016-01-01

    Descriptive statistics is the branch of statistics that gives recommendations on how to summarize clearly and simply research data in tables, figures, charts, or graphs. Before performing a descriptive analysis it is paramount to summarize its goal or goals, and to identify the measurement scales of the different variables recorded in the study. Tables or charts aim to provide timely information on the results of an investigation. The graphs show trends and can be histograms, pie charts, "box and whiskers" plots, line graphs, or scatter plots. Images serve as examples to reinforce concepts or facts. The choice of a chart, graph, or image must be based on the study objectives. Usually it is not recommended to use more than seven in an article, also depending on its length.

  19. Experimental statistics

    CERN Document Server

    Natrella, Mary Gibbons

    1963-01-01

    Formulated to assist scientists and engineers engaged in army ordnance research and development programs, this well-known and highly regarded handbook is a ready reference for advanced undergraduate and graduate students as well as for professionals seeking engineering information and quantitative data for designing, developing, constructing, and testing equipment. Topics include characterizing and comparing the measured performance of a material, product, or process; general considerations in planning experiments; statistical techniques for analyzing extreme-value data; use of transformations

  20. Typing of avian pathogenic Escherichia coli strains by REP-PCR Tipificação de amostras aviárias patogênicas de Escherichia coli pela REP-PCR

    Directory of Open Access Journals (Sweden)

    Marcelo Brocchi

    2006-06-01

    Full Text Available In the present study the repetitive extragenic palindromic (REP polymerase chain reaction (PCR technique was used to establish the clonal variability of 49 avian Escherichia coli (APEC strains isolated from different outbreak cases of septicemia (n=24, swollen head syndrome (n=14 and omphalitis (n=11. Thirty commensal strains isolated from poultry with no signs of these illnesses were used as control strains. The purified DNA of these strains produced electrophoretic profiles ranging from 0 to 15 bands with molecular sizes varying from 100 bp to 6.1 kb, allowing the grouping of the 79 strains into a dendrogram containing 49 REP-types. Although REP-PCR showed good discriminating power it was not able to group the strains either into specific pathogenic classes or to differentiate between pathogenic and non-pathogenic strains. On the contrary, we recently demonstrated that other techniques such as ERIC-PCR and isoenzyme profiles are appropriate to discriminate between commensal and APEC strains and also to group these strains into specific pathogenic classes. In conclusion, REP-PCR seems to be a technique neither efficient nor universal for APEC strains discrimination. However, the population clonal structure obtained with the use of REP-PCR must not be ignored particularly if one takes into account that the APEC pathogenic mechanisms are not completely understood yet.A técnica de REP (Repetitive extragenic palindrome-PCR foi utilizada para avaliar a variabilidade genética de 49 amostras de Escherichia coli patogênicas para aves (APEC, isoladas de aves de corte (frangos em diferentes surtos de septicemia (n=24, síndrome da cabeça inchada (n=14 e onfalite (n=11. Trinta amostras comensais, isoladas de frangos sem sinais de doença, foram utilizadas como controle. A análise do perfil eletroforético obtido por reação de REP-PCR utilizando DNA purificado das amostras evidenciou a amplificação de 0 a 15 bandas de DNA com pesos moleculares

  1. Agripino Nazareth e o movimento operário da Primeira República

    Directory of Open Access Journals (Sweden)

    Aldrin Armstrong Silva Castellucci

    2012-12-01

    Full Text Available Agripino Nazareth (1886-1961 se destacou como liderança socialista do movimento operário brasileiro ao longo da Primeira República. Depois de 1930, passou a integrar os quadros do Ministério do Trabalho e da Justiça do Trabalho, aposentando-se como Procurador do Trabalho no início de 1960 e falecendo no dia 1º de agosto de 1961. Neste artigo, analisaremos o primeiro momento de sua trajetória, quando se associou a outros militantes das mais variadas correntes político-ideológicas, envolvendo-se em movimentos de diversos matizes e assumindo diferentes compromissos.

  2. Triatoma baccalaureatus: sobre a crise do bacharelismo na Primeira República

    Directory of Open Access Journals (Sweden)

    Ricardo Sontag

    2010-07-01

    Full Text Available Este trabalho pretende abordar a crise do bacharelismo (hegemônico durante o Império nas primeiras décadas do século XX, principalmente por meio da literatura, relacionando-a com as transformações que estavam ocorrendo no ensino e no saber jurídico. Ao longo da Primeira República, à medida que outras figuras passam a ganhar espaço no cenário público (engenheiros, sanitaristas, etc., o bacharelismo passa a ser duramente questionado, aprofundando as críticas que já vinham sendo levadas a cabo no final do século XIX pelo positivismo cientificista; a partir disso, começa a se formar a cultura do tecnicismo jurídico. Palavras-chave: História do Direito. Bacharelismo. Positivismo cientificista. Tecnicismo.

  3. Cargos militares y república de indios en el noroeste novohispano, siglos XVII y XVIII

    Directory of Open Access Journals (Sweden)

    Dora Elvia Enríquez Licón

    2014-01-01

    Full Text Available En el presente artículo expongo los rasgos primordiales de las repúblicas de indios constituidas en los pueblos de misión jesuíticos en el noroeste novohispano, destacando la gran relevancia del factor militar. La inclusión de los cargos militares fue el aporte más significativo que hicieron los indios septentrionales en la constitución de sus cabildos. En esta región fue imposible desarmar a los indígenas pues los conquistadores requerían su apoyo para asegurar el avance de la frontera. De esta manera, los pobladores originarios, al continuar ejerciendo sus habilidades guerreras, dejaron su impronta en la conformación de las estructuras sociales y políticas regionales.

  4. A paradiplomacia financeira no Brasil da República Velha, 1890-1930

    OpenAIRE

    Maia,José Nelson Bessa; Saraiva,José Flávio Sombra

    2012-01-01

    Neste artigo, visa-se a analisar um caso de extroversão de governos estaduais no campo do financiamento externo no período da chamada República Velha (1890-1930) no Brasil. Com base na definição de "paradiplomacia financeira", argumenta que a experiência histórica brasileira nesse aspecto teria sido um caso típico de ação paradiplomática. Amplo levantamento estatístico dos empréstimos externos por estados, o resgate das fontes documentais primárias sobre o assunto e a contextualização históri...

  5. A paradiplomacia financeira no Brasil da República Velha, 1890-1930

    Directory of Open Access Journals (Sweden)

    José Nelson Bessa Maia

    2012-01-01

    Full Text Available Neste artigo, visa-se a analisar um caso de extroversão de governos estaduais no campo do financiamento externo no período da chamada República Velha (1890-1930 no Brasil. Com base na definição de "paradiplomacia financeira", argumenta que a experiência histórica brasileira nesse aspecto teria sido um caso típico de ação paradiplomática. Amplo levantamento estatístico dos empréstimos externos por estados, o resgate das fontes documentais primárias sobre o assunto e a contextualização histórica pertinente dão sustentação à caracterização do período como uma fase de paradiplomacia financeira precoce.

  6. DEMO_REP: A LABS TOOL FOR TEACHING DATA REPLICATION / DEMO_REP: HERRAMIENTA PARA LABORATORIOS EN LA ENSEÑANZA DE RÉPLICA DE DATOS

    Directory of Open Access Journals (Sweden)

    Ileane Martí Pérez

    2013-02-01

    Full Text Available The process of training professionals in information technologies is a key aspect in the development of the country. University Informatics Science is one of the main centers dedicated to this process, also has postgraduate training programs to further advanced topics not mentioned in the pregraduate. One such program is the "DIPLOMADO EN TECNOLOGÍAS DE BASES DE DATOS POSTGRESQL," which has a number of courses to obtain expertise in the subject of databases in PostgreSQL Manager. In this paper show how affects in the understanding of the process of data replication, the use of the software tool "Demo_rep" for laboratory exercises replication. It also describes the main features of software tool.RESUMENEl proceso de formación de los profesionales en tecnologías de la informática es un aspecto clave en el desarrollo del país. La Universidad de las Ciencias Informáticas es uno de los principales centros que se dedica a este proceso, la misma consta de programas de formación postgraduada para profundizar en temas que no aparecen incluidos en los programas analíticos de las asignaturas de pregrado. Uno de estos programas es el “DIPLOMADO EN TECNOLOGÍAS DE BASES DE DATOS POSTGRESQL”, el cual cuenta con una serie de cursos para lograr experticia en la temática de las bases de datos en el gestor PostgreSQL. En el presente trabajo se muestra cómo incide en la comprensión del proceso de la replicación de datos, la utilización de una herramienta informática “Demo_rep” para realizar los ejercicios de laboratorio de réplica. Se describe además las principales funcionalidades de la misma.

  7. Improvement of the Cramer classification for oral exposure using the database TTC RepDose - A strategy description

    NARCIS (Netherlands)

    Tluczkiewicz, I.; Buist, H.E.; Martin, M.T.; Mangelsdorf, I.; Escher, S.E.

    2011-01-01

    The present report describes a strategy to refine the current Cramer classification of the TTC concept using a broad database (DB) termed TTC RepDose. Cramer classes 1-3 overlap to some extent, indicating a need for a better separation of structural classes likely to be toxic, moderately toxic or of

  8. Mida on vaja teha õpilaskodude arendamiseks? / Ale Sprenk, Karin Saare, Merike Mändla, Mailis Reps...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad Krabi põhikooli direktor, õpilaskodu mõtte algataja Ale Sprenk, Kasari põhikooli direktor Karin Saare, haridus- ja teadusministeeriumi üldharidusosakonna peaekspert Merike Mändla, riigikogu liige, endine haridusminister Mailis Reps ja Otepää gümnaasiumi direktor Aivo Meema

  9. Open-Source Wax RepRap 3-D Printer for Rapid Prototyping Paper-Based Microfluidics.

    Science.gov (United States)

    Pearce, J M; Anzalone, N C; Heldt, C L

    2016-08-01

    The open-source release of self-replicating rapid prototypers (RepRaps) has created a rich opportunity for low-cost distributed digital fabrication of complex 3-D objects such as scientific equipment. For example, 3-D printable reactionware devices offer the opportunity to combine open hardware microfluidic handling with lab-on-a-chip reactionware to radically reduce costs and increase the number and complexity of microfluidic applications. To further drive down the cost while improving the performance of lab-on-a-chip paper-based microfluidic prototyping, this study reports on the development of a RepRap upgrade capable of converting a Prusa Mendel RepRap into a wax 3-D printer for paper-based microfluidic applications. An open-source hardware approach is used to demonstrate a 3-D printable upgrade for the 3-D printer, which combines a heated syringe pump with the RepRap/Arduino 3-D control. The bill of materials, designs, basic assembly, and use instructions are provided, along with a completely free and open-source software tool chain. The open-source hardware device described here accelerates the potential of the nascent field of electrochemical detection combined with paper-based microfluidics by dropping the marginal cost of prototyping to nearly zero while accelerating the turnover between paper-based microfluidic designs. © 2016 Society for Laboratory Automation and Screening.

  10. Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal

    NARCIS (Netherlands)

    Peters, A.K.; Leonards, P.E.G.; Zhao, B.; Bergman, A.; Denison, M.S.; Berg, van den M.

    2006-01-01

    The TEF system for dioxin-like compounds has included assignment of TEF values for mono-ortho polychlorinated biphenyls (MO-PCBs). Small traces of aryl hydrocarbon receptor (AhR)-active impurities could result in artifactually higher relative potency (REP) values. MO-PCBs -105, -118, -156, and -167

  11. A Primeira República Portuguesa (1910-1926: partidos e sistema político

    Directory of Open Access Journals (Sweden)

    Baiôa, Manuel

    2014-04-01

    Full Text Available For historical, organisational, clientelist, violent and constitutional reasons the Portuguese Republican Party became the dominant party in the political system of the Portuguese First Republic (1910-1926. The opposition felt alternation via elections would be difficult to achieve so resorted to violent and unconstitutional practices to reach government. The Portuguese political parties modernised themselves in this period, but failed to turn into mass parties. In major cities they acted as a cadre party and in the rural area as a party of notables. The First Republic failed to take solid steps to democratise the political system were And Portugal remained tied to the liberal and elitist tradition of the nineteenth century, although in a republican version.El Partido Republicano Portugués se convirtió en el partido dominante del sistema político de la Primera República Portuguesa (1910-1926 debido a causas históricas, organizacionales, clientelistas, violentas y constitucionales. La oposición sentía que difícilmente conseguiría la alternancia política a través de elecciones, y por lo tanto, recurre a prácticas violentas e inconstitucionales para llegar al gobierno. Los partidos políticos portugueses se modernizaron en este período, pero no se convirtieron en partidos de masas. En las principales ciudades actuaban como partidos de cuadros y en las zonas rurales como partidos de notables. Durante la Primera República no se dieron pasos consistentes para democratizar el sistema político. Portugal se mantuvo ancorado a la tradición liberal y elitista del siglo XIX, aunque en una versión republicana.

  12. Los médicos del exilio repúblicano en Venezuela

    Directory of Open Access Journals (Sweden)

    José Francisco Tinao Martín-Peña

    2009-11-01

    Full Text Available La guerra civil española provocó el exilio de un importante número de científicos e intelectuales. Dentro de ellos numerosos médicos saldrían de España obligados por su defensa de la República o su ideología democrática. Una gran mayoría se establecieron en América Latina. Venezuela es el segundo país donde más facultativos acoge, tras México. En el presente trabajo se analiza cuales fueron las circunstancias históricas que permitieron esta acogida, y se hace referencia a alguna de las personalidades y sus campos de trabajo en su nuevo país de acogida. Dentro de la historia social de la medicina española existe un espacio vacío sobre el exilio médico y sobre la represión interior ejercida físicamente o simplemente como depurados de numerosos médicos que se vincularon de distinto modo con los ideales de modernidad de la República Española.______________ABSTRACT:The Spanish Civil War led to the exile of a large number of scientists and intellectuals. Among them, many doctors escaped from Spain because of their defense of the Republic or their democratic ideology. A large majority were established in Latin America. Venezuela is the second country of welcome, after Mexico. In this paper we analyze what were the historical circumstances that allowed this host, and it is made reference to some personalities and their fields of work in their new host country. Within the social history of Spanish medicine, there is an empty space on the exile of this category and their internal repression or the purged of many doctors linked to the ideals of modernity of the Spanish Republic.

  13. Phylogenetic relationships, virulence factors and Rep-PCR epidemiological analysis of E. coli from human sources

    Directory of Open Access Journals (Sweden)

    Simona Caroppo

    2010-06-01

    Full Text Available The potential of Escherichia coli to cause of extra-intestinal infections was studied on a group of 94 clinical isolates. In this work, 32 E. coli isolates from urinary tract infections, 25 from bacteraemia, 12 from low respiratory tract infections, and 25 from the normal commensal flora were characterized for the phylogenetic type, the virulence factors (VFs carriage and the Rep-PCR clonal composition.The B2 phylogenetic type was predominant among the urinary isolates (59%, the B2 and D strains among the haematic isolates (32% and 32%.The A phylogenetic type was predominant among the commensal and the respiratory isolates (52% and 58% respectively.The distribution of the B2 type strains among the urinary isolates and of the D type strains among the faecal isolates was suggesting a urinary-origin for the B2 phylogenetic type isolates found in the blood and a direct faecal derivation for the haematic isolates with D phylogenetic type.Twenty-nine VFs were analyzed.The B2 and D type strains carried a higher burden of VFs than the A and B1 phylogenetic type strains (average of VFs/strain = 8 vs 3. Some of the VFs were homogeneously distributed among the phylogenetic types (fimH, iutA, fyuA, traT. The PAI, papGII, ibeA, KpsMTIII were exclusive of B2 and D phylogenetic type strains, while sfa/foc, focG, cnf1, hlyA and rfc were exclusively observed among the B2 type strains.The clustering analysis by Rep-PCR distinguished two groups of strains, the first including 96.77% of B2 and D type strains, while the second encompassing 91,5% of A and B1 type strains.

  14. Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI+

    Directory of Open Access Journals (Sweden)

    Fátima eGasset-Rosa

    2015-04-01

    Full Text Available The yeast translation termination factor Sup35p, by aggregating as the [PSI+] prion, enables ribosomes to read-through stop codons, thus expanding the diversity of the Saccharomyces cerevisiae proteome. Yeast prions are functional amyloids that replicate by templating their conformation on native protein molecules, then assembling as large aggregates and fibers. Prions propagate epigenetically from mother to daughter cells by fragmentation of such assemblies. In the N-terminal prion-forming domain, Sup35p has glutamine/asparagine-rich oligopeptide repeats (OPRs, which enable propagation through chaperone-elicited shearing. We have engineered chimeras by replacing the polar OPRs in Sup35p by up to five repeats of a hydrophobic amyloidogenic sequence from the synthetic bacterial prionoid RepA-WH1. The resulting hybrid, [REP-PSI+], i was functional in a stop codon read-through assay in S. cerevisiae; ii generates weak phenotypic variants upon both its expression or transformation into [psi-] cells; iii these variants correlated with high molecular weight aggregates resistant to SDS during electrophoresis; and iv according to fluorescence microscopy, the fusion of the prion domains from the engineered chimeras to the reporter protein mCherry generated perivacuolar aggregate foci in yeast cells. All these are signatures of bona fide yeast prions. As assessed through biophysical approaches, the chimeras assembled as oligomers rather than as the fibers characteristic of [PSI+]. These results suggest that it is the balance between polar and hydrophobic residues in OPRs what determines prion conformational dynamics. In addition, our findings illustrate the feasibility of enabling new propagation traits in yeast prions by engineering OPRs with heterologous amyloidogenic sequence repeats.

  15. Statistical mechanics

    CERN Document Server

    Sheffield, Scott

    2009-01-01

    In recent years, statistical mechanics has been increasingly recognized as a central domain of mathematics. Major developments include the Schramm-Loewner evolution, which describes two-dimensional phase transitions, random matrix theory, renormalization group theory and the fluctuations of random surfaces described by dimers. The lectures contained in this volume present an introduction to recent mathematical progress in these fields. They are designed for graduate students in mathematics with a strong background in analysis and probability. This book will be of particular interest to graduate students and researchers interested in modern aspects of probability, conformal field theory, percolation, random matrices and stochastic differential equations.

  16. Statistical Neurodynamics.

    Science.gov (United States)

    Paine, Gregory Harold

    1982-03-01

    The primary objective of the thesis is to explore the dynamical properties of small nerve networks by means of the methods of statistical mechanics. To this end, a general formalism is developed and applied to elementary groupings of model neurons which are driven by either constant (steady state) or nonconstant (nonsteady state) forces. Neuronal models described by a system of coupled, nonlinear, first-order, ordinary differential equations are considered. A linearized form of the neuronal equations is studied in detail. A Lagrange function corresponding to the linear neural network is constructed which, through a Legendre transformation, provides a constant of motion. By invoking the Maximum-Entropy Principle with the single integral of motion as a constraint, a probability distribution function for the network in a steady state can be obtained. The formalism is implemented for some simple networks driven by a constant force; accordingly, the analysis focuses on a study of fluctuations about the steady state. In particular, a network composed of N noninteracting neurons, termed Free Thinkers, is considered in detail, with a view to interpretation and numerical estimation of the Lagrange multiplier corresponding to the constant of motion. As an archetypical example of a net of interacting neurons, the classical neural oscillator, consisting of two mutually inhibitory neurons, is investigated. It is further shown that in the case of a network driven by a nonconstant force, the Maximum-Entropy Principle can be applied to determine a probability distribution functional describing the network in a nonsteady state. The above examples are reconsidered with nonconstant driving forces which produce small deviations from the steady state. Numerical studies are performed on simplified models of two physical systems: the starfish central nervous system and the mammalian olfactory bulb. Discussions are given as to how statistical neurodynamics can be used to gain a better

  17. Comparison of multilocus sequence typing (MLST) and repetitive sequence-based PCR (rep-PCR) fingerprinting for differentiation of Campylobacter jejuni isolated from broiler in Chiang Mai, Thailand.

    Science.gov (United States)

    Patchanee, Prapas; Chokboonmongkol, Chomporn; Zessin, Karl-Hans; Alter, Thomas; Pornaem, Sarinya; Chokesajjawatee, Nipa

    2012-11-01

    We compared rapid fingerprinting using repetitive sequence-based PCR (rep-PCR) for subtyping Campylobacter jejuni isolates to the widely used multilocus sequence typing (MLST). Representative C. jejuni isolates (n = 16) from broilers were analyzed using MLST and rep-PCR. Both techniques demonstrated an equal discriminatory power of 0.8917, and 9 subgroups were identified. Clonal identification of all 16 isolates was identical for both techniques. The rep-PCR as described in this study may be used as a rapid and cost-effective alternative for subtyping of C. jejuni isolates, or as an effective screening tool in large epidemiological studies.

  18. El montaje de la transición argentina. Un análisis de los films La República perdida, La República perdida II y Evita, quien quiera oír que oiga

    Directory of Open Access Journals (Sweden)

    Paola Judith Margulis

    2012-01-01

    Full Text Available El presente artículo se propone reconstruir una zona de la historia del documental argentino a partir del abordaje de tres films que tuvieron un alto impacto en Argentina hacia la transición democrática: La República perdida (Miguel Pérez, 1983, su secuela La República perdida II (Miguel Pérez, 1986 y Evita, quien quiera oír que oiga (Eduardo Mignogna, 1984. Dada la importancia de estos films -tanto en términos políticos como de impacto en el público-, intentaremos situarlos en contexto y analizar algunos aspectos inherentes a su lógica fílmica.

  19. Lecturas de un sueño. (Sobre la República literaria de Saavedra Fajardo

    Directory of Open Access Journals (Sweden)

    Rodríguez, Juan Carlos

    2013-12-01

    Full Text Available The author of the República Literaria, a diplomatic voyager from the 17th Century, dreams of a city of paper: to read a city as if it were a book and to read a book as if it were a journey throughout literary history. Is it possible? On this journey across all of written culture that Saavedra describes, where the inhabitants of the city are authors of ‘literary’ texts and the arts live together with the sciences and the muses, the author analyses with subtle irony the present and the tradition of everything that surrounds the production of all that is written. With the classic resource of the ‘Dream’ he shows an incredibly clear panorama where we can recognize the beginnings of capitalism, in which books have gone from being considered repositories of wisdom and common sense, to becoming mere marketplace objects.El autor de la República Literaria, un diplomático viajero del siglo XVII, sueña una ciudad de papel: leer una ciudad como si fuera un libro y leer un libro como si fuera un viaje a través de la historia literaria. ¿Es posible? En este recorrido por toda la cultura escrita que traza Saavedra, donde los habitantes de la ciudad son los autores de los textos «literarios» y las artes conviven con las ciencias y las musas, el autor desmenuza con finísima ironía la actualidad y la tradición de todo lo que rodea a la producción de lo escrito. Con el clásico recurso del «Sueño» muestra un panorama increíblemente nítido donde podemos reconocer los inicios del capitalismo en el que los libros han pasado de ser considerados como un depósito de sabiduría y cordura a tener carácter de mero objeto de mercado.

  20. La República Frustrada y el enemigo perverso. La Guerra del Pacífico en la Historia de la República del Perú de Jorge Basadre

    OpenAIRE

    Daniel Parodi Revoredo

    2010-01-01

    Este ensayo descubre los imaginarios que la Historia de la República del Perú de Jorge Basadre proyecta acerca del Perú y de Chile. Propone que la utopía liberal-nacionalista es el eje central en la obra examinada, la que, sin embargo, sugiere el fracaso del proyecto nacional peruano. Por su parte, la imagen de Chile se construye sobre atributos tales como el orden, el imperialismo y la agresividad.

  1. A Reportagem na tv: Caco Barcellos: um repórter e a injustiça social

    OpenAIRE

    Plaça Júnior, João

    2004-01-01

    Destacar a importância da reportagem investigativa, e mostrar o valor que deve ser observado no empenho da atuação profissional ética de um repórter de televisão, capaz de mudar o rumo da história política recente do Brasil, é o que se propõe o presente trabalho. A prática do jornalismo autêntico demonstra ser transformadora. É o que acontece com a atuação do repórter Caco Barcellos. Ele se propôs a perseguir uma história por mais de um ano e, ao final, mostrar uma verdade escondida durante 3...

  2. 150 años despues: Constitución de la república de Tunja

    Directory of Open Access Journals (Sweden)

    José Hurtado García

    1961-12-01

    Full Text Available En Tunja perduran abiertos los corazones y los zaguanes. La Villa noble de Suárez Rendón, embelesada en el canto de la Madre Castillo y de don Juan de Castellanos, amaneció en la República con el sacrificio de sus hijos y con sus ideas proceras. Precisamente en este mes de diciembre de 1961 -el nueve- se cumplen los ciento cincuenta años de la expedición de su Constitución, cuyo título definido reza: " Constitución de la República de Tunja sancionada en plena Asamblea de los Representantes de toda la Provincia, en sesiones continuas desde el 21 de noviembre hasta el 9 de diciembre de 1811. Año Segundo de la Transformación Política del Nuevo Reyno de Granada".

  3. Liberalismo, iluminismo y romanticismo: el problema de la libertad en dos novelas de la República Restaurada

    Directory of Open Access Journals (Sweden)

    Verónica Hernández Landa Valencia

    2016-07-01

    Full Text Available El artículo propone una reflexión en torno a la forma como influyen tres corrientes de pensamiento, el liberalismo, el iluminismo y el romanticismo, en la representación del problema de la libertad en dos novelas históricas publicadas en la República Restaurada: Monja y casada, virgen y mártir, de Vicente Riva Palacio, y El pecado del siglo, de José Tomás de Cuéllar. Se busca mostrar que dichas corrientes se entrecruzan en un solo texto, que ello contribuye a la conformación de un concepto de libertad restringida y que la forma específica que adquiere ese concepto se explica a partir de la postura ideológica y política de los autores en el contexto de la República Restaurada.

  4. El pensamiento cultural cubano de la República ¿Teoría del Arte en el Caribe?

    Directory of Open Access Journals (Sweden)

    Eliannys Zamora-Arevalo

    2016-02-01

    Full Text Available El estudio sobre el devenir del pensamiento cultural cubano de la República es de vital importancia para la comprensión de sus esencialidades dentro de la cultura nacional. El presente trabajo tiene como objetivo realizar un análisis crítico-descriptivo del libro El pensamiento cultural cubano de la República. ¿Teoría del Arte en el Caribe? de la joven investigadora cubana Yaneidys Arencibia Coloma. La obra propone la resignificación del pensamiento cultural republicano a partir de un análisis de títulos paradigmáticos dentro de la obra de Fernando Ortiz, Jorge Mañach, Juan Marinello, Alejo Carpentier y José Lezama escritos entre 1923 y 1961.

  5. Use of REP- and ERIC-PCR to reveal genetic heterogeneity of Vibrio cholerae from edible ice in Jakarta, Indonesia

    Directory of Open Access Journals (Sweden)

    Waturangi Diana E

    2012-03-01

    Full Text Available Abstract Background Vibrio cholerae is the causative organism of waterborne disease, cholera. V. cholerae has caused many epidemics and pandemics of cholera for many years. In this study, V. cholerae recovered from edible ice were investigated for their genetic diversity using Enterobacterial Repetitive Intergenic Consensus (ERIC PCR and Repetitive Extragenic Palindromic (REP PCR. Isolation was done using selective medium and the presumptive isolates were confirmed through biochemical and serological assays. Results Seventy-five isolates of V. cholerae were recovered from ice samples collected from different locations of Jakarta. Specifically, 19 of them were identified as O1 serotype, 16 were Ogawa, 3 isolates were Inaba and the remaining isolates were non-O1. The fingerprinting profiles of V.cholerae isolated from ice samples were very diverse. Conclusion This result showed that the ERIC sequence is more informative and discriminative than REP sequence for analysis of V. cholerae diversity.

  6. Representações cômicas da República no contexto do Getulismo

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    Elio Chaves Flores

    2001-01-01

    Full Text Available Neste artigo analiso as representações cômicas e discursivas da República e a trajetória política de Getúlio Vargas, a partir de uma narrativa que se assenta no método regressivo. Para isso, trabalhei com uma série de caricaturas publicadas em jornais e revistas na duração entre 1930 e 1954, confrontando a intertextualidade dessas imagens com alguns discursos satíricos e irônicos produzidos por memorialistas. Procuro demonstrar que há semelhança entre a inversão humorística e a textualidade da memória, quando inventam a respeito de seu tempo e dos outros imagens verossímeis.This article analyses the comic and discursive representations of the Brazilian Republic and Getúlio Vargas’ political career, starting from a narrative constructed in the regressive method. For that, I worked with a series of cartoons published in newspapers and magazines in the span of time between 1954 and 1930, matching the intertextuality of these images with some of the satiric and ironic speeches produced by witnesses. It is demonstrated there is likeness between the comic inversion and the textuality of the memory, when they invent concerning their time and other ones, the verisimilitude of the images.

  7. O sistema oligárquico representativo da Primeira República

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    Wanderley Guilherme dos Santos

    2013-03-01

    Full Text Available Entre les absolutismes des XVIIe et XVIIIe siècles, d'une part, et les variantes démocratiques repérées après la Seconde Guerre Mondiale, d'autre part, demeure un brouillard conceptuel gênant la compréhension de l'histoire politico-institutionnelle de cette période. L'oligarchie, traitée soit comme germe de démocratie soit comme vestige autocratique, reste une période soumise à la subjectivité. On présente un modèle analytique différent de ce que serait un système oligarchique, à la validité trans-locale, en cherchant à montrer la façon dont l'histoire du Second Empire et de la Première République apparaitrait au moyen d'une approche préalable utilisant le modèle général.

  8. Leptospirosis porcina: prevalencia serológica en establecimientos productores de la República Argentina

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    Jessica Petrakovsky M.

    2013-03-01

    Full Text Available Objetivo. Detectar la presencia de anticuerpos contra Leptospira sp en cerdos que no presentaban sintomatología clínica, pertenecientes a establecimientos de producción porcina ubicados en todo el territorio de la República Argentina. Materiales y métodos. La asignación de predios y muestras se realizó en forma proporcional a los registrados en cada provincia a lo largo de todo el país. En total se estudiaron 1.524 predios, de los cuales se tomaron 19.872 muestras de suero y en la primera etapa se procesaron 3.631 de los mismos. Este estudio toma en consideración zonas identificadas por provincia, municipio y predios. Los sueros fueron analizados por la técnica de MAT (prueba de microaglutinación. Resultados. El 30% de las muestras resultaron positivas a la prueba tamiz empleada (primera etapa del MAT. La mayoría presentó coaglutininas a dos o a tres serovariedades. Al realizar la titulación de los sueros (segunda etapa del MAT, el porcentaje de positividad se mantuvo, siendo los serovares de mayor prevalencia Castellonis e Icterohaemorrhagiae. El 90% de las muestras presentó un título final de 1:200. Conclusiones. La existencia de sueros positivos en todas las provincias indica el contacto de los animales con la leptospira a lo largo de todo el país.

  9. Les revistes bilingües a la Tortosa de la II República

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    M. Carme Gombau Domingo

    2016-06-01

    Full Text Available En l’àmbit de la premsa tortosina en català del primer terç del segle xx es donen dues actituds lingüístiques: la fabriana i la tortosinista. La primera, partidària del model de llengua de l’IEC, era minoritària als anys vint però es generalitza a partir dels anys trenta (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita; mentre que el tortosinisme, que es correspon amb una ideologia cada cop més localista i que eleva el «parlar tortosí» a la categoria de llengua, queda reduït durant la II República a tres revistes bilingües: La Zuda, Germanor i La Santa Cinta. There were two linguistic actitudes in the tortosine press of the first third in the 20th century: the fabriana amb the tortosinista. The fabriana, in favour of the IEC linguistic model, was in minority during the 20’s, but it became widespread from the 30’s (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita. The second, the tortosinista, had a local ideology and compared the tortosinisme talk as a complet language, but it was reduced during the ii Republic to three magazines: La Zuda, Germanor i La Santa Cinta.

  10. Sistema de salud de República Dominicana The health system of Dominican Republic

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    Magdalena Rathe

    2011-01-01

    Full Text Available En este trabajo se describen las condiciones de salud de la República Dominicana y, con mayor detalle, el sistema de salud dominicano, incluyendo su estructura y cobertura, sus fuentes de financiamiento, el gasto en salud, los recursos físicos, materiales y humanos de los que dispone, las tareas de rectoría que desarrolla el Ministerio de Salud Pública y la generación de información. También se discuten la participación de los usuarios en la operación y evaluación del sistema de salud y las más recientes innovaciones implementadas, dentro de las que destacan la nueva Ley General de Salud, la nueva Ley de Seguridad Social y el Plan Decenal de Salud.This paper describes the health conditions in Dominican Republic and the characteristics of the Dominican health system, including its structure and coverage, its financial sources, the health expenditure, the physical, material and human resources available, the stewardship functions developed by the Ministry of Public Health and the generation of health information. The participation of health care users in the operation and evaluation of the system and the most recent policy innovations, including the new General Health Law, the new Social Security Law and the Decennial Health Plan are also discussed.

  11. Mapa educativo nacional. Una experiencia en la República Argentina

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    Horacio Rodolfo Bozzano

    2006-01-01

    Full Text Available El Proyecto Mapa Educativo Nacional (MEN es un SIG generado a partir del desarrollo e integración de 24 Mapas Educativos Provinciales sobre la base de un modelo conceptual general, con una visión dinámica de los 49.000 establecimientos educativos, así como de su contexto territorial. Los objetivos del trabajo son: a sistematizar los aportes al Proyecto MEN desde la teoría cartográfica, reconociendo instancias de concepción, construcción y comunicación de los mapas que lo integran, así como vinculaciones entre territorio, espacio y espacialidades emergentes de la concreción de la tarea; y b identificar en qué medida la concreción del Proyecto MEN en la República Argentina contribuye a fortalecer un enfoque dialéctico conocimiento-realidad sobre el territorio y la gestión aplicado a un objeto de estudio e intervención concreto de desarrollo institucional, con el propósito de promover un círculo virtuoso de transformación entre sujetos de cambio y agentes de desarrollo.

  12. Characterization of Penicillium species by ribosomal DNA sequencing and BOX, ERIC and REP-PCR analysis.

    Science.gov (United States)

    Redondo, Cristina; Cubero, Jaime; Melgarejo, Paloma

    2009-07-01

    The genus Penicillium is one of the largest and widely distributed fungal genera described to date. As a result, its taxonomic classification and species discrimination within this genus has become complicated. In this study, 52 isolates that belonged to the Penicillum genus and other related genera were characterized using two DNA-based methods: (i) analysis of the nucleotide sequences of internal transcribed spacers in ribosomal DNA and (ii) analysis of DNA fingerprints that were generated by polymerase chain reactions with specific primers for enterobacterial repetitive intergenic consensus (ERIC) and repetitive extragenic palindromic (REP) sequences, and BOX elements. Using both methods, Penicillium species were discriminated from other fungal genera. Furthermore, Penicillium species that include strains which are used as biocontrol agents, such as P. glabrum, P. purpurogenum, and P. oxalicum, could be distinguished from other Penicillium species using these techniques. Based on our findings, we propose that a polyphasic approach that includes analysis of the nucleotide sequences of ribosomal DNA and detecting the presence of highly conserved, repeated nucleotide sequences can be used to determine the genetic relationships between different Penicillium species. Furthermore, we propose that our results can be used as a start point to develop a strategy to monitor the environmental presence of particular strains of Penicillium species when they are used as biocontrol agents.

  13. Rep-Rated X-ray Damage and Ablation Experiments for IFE and ICF Applications

    Energy Technology Data Exchange (ETDEWEB)

    Latkowski, J F; Abbott, R P; Payne, S A; Reyes, S; Schmitt, R C; Speth, J A

    2003-09-08

    The response of materials to high-dose x-ray exposures needs to be understood for inertial fusion energy (IFE) and inertial confinement fusion applications, where the requirements for IFE are considerably more stringent. In the IFE context, x-ray damage and/or small levels of ablation are of importance for component survivability, generation of debris, and contamination. Ablation quantities of even 1 angstrom per shot would result in material removal of more than 1 cm per year of operation. If even one part in a million of this material made its way to the final optics, it would coat them with a thickness equivalent to several waves of the laser light. Also, small-scale melting and thermomechanical effects, such as fatigue, can result from x-ray heating. These effects potentially become important when multiple shots are considered, and thus, their study requires use of rep-rated experiments. As a part of the High-Average Power Laser Program, the XAPPER experiment has been initiated at Lawrence Livermore National Laboratory. XAPPER produces high doses of low-energy x-rays at repetition rates of up to 10 Hz. Study of x-ray damage is underway. An overview of facility capabilities, results to date, and future plans are provided.

  14. Desterrando formas poéticas en la República de Platón.

    Directory of Open Access Journals (Sweden)

    Sergio Ariza.

    2009-12-01

    Full Text Available Este artículo examina un aspecto seminal, pero sorprendente en la crítica de Platón de la poesía: Platón destierra a los contenidos, no sólo particular, y los autores, pero las formas poéticas también ellas mismas, en concreto la forma mimética. El análisis muestra que la principal razón para desterrar tales reside en el hecho de que Platón descubrió que la forma como la forma (con independencia de su contenido tiene un carácter autónomo y se rige por criterios estéticos y no moral. Estos criterios estéticos son incompatibles con la ideología que apoya la polis ideal. Esto pone de relieve el mérito del análisis de Platón de que no está en la evaluación de la actividad poética, sino en la identificación de las puramente estéticas y sus consecuencias sobre el programa político de la República

  15. Globo Repórter no Twitter: o discurso coletivo dos telespectadores

    Directory of Open Access Journals (Sweden)

    Bianca Pereira da Silva

    2017-04-01

    Full Text Available This study aims to reveal the comments of Twitter made by Globo Reporter viewers during the program's exhibition. Among the specific objectives are: a profile of the program and a historical analysis of the emergence of social networks. The choice of Globo Reporter was because it is one of the programs that has been in the air for the longest time on Brazilian TV. For that, it was used as theoretical reference: Globo Repórter (Andrade, 2002; (Souza, 2004, (Rezende, 2000; Social Network on the Internet (Recuero, 2009, (Body & Ellison, 2007 and Twitter (Santaella and Lemos, 2009, (Zago, 2014. As a method to develop this study,was usedthe Collective Subject Discourse technique proposed by Lefevre & Lefévre (2003. To develop the technique, two editionsof the GloboReporter were analyzed and the viewers' comments were collected through the hashtag #GloboReporter, during the program's display. Among the conclusions, it can be said that when watching the GloboReporter, the population relates its reality to what is displayed in the program.

  16. La plantación que no se repite: las historias azucareras de la República Dominicana y Puerto Rico 1870-1930

    Directory of Open Access Journals (Sweden)

    García Muñíz, Humberto

    2005-04-01

    Full Text Available This article focuses on a comparative analysis of the sugar industry in both Dominican Republic and Porto Rico, between 1870 and 1930. It is argued that the development and interaction of plantation bases were different in both cases, and concludes that «no two plantations are alike». The study is based on primary and secondary sources, sectorial magazines, statistics and oral testimonies.

    Analizando comparativamente la historia de la industria del azúcar de caña en la República Dominicana y Puerto Rico en el período comprendido entre 1870 y 1930, este trabajo argumenta que el desarrollo de los elementos de la plantación y su conjunción fueron distintos en ambos casos y concluye que «la plantación no se repite». La documentación consultada para realizarlo incluye fuentes primarias y secundarias, artículos de revistas especializadas en el sector, estadísticas de la producción y testimonios orales.

  17. CARACTERIZACIÓN MOLECULAR MEDIANTE rep-PCR DE AISLADOS NATIVOS DE Bacillus thuringiensis, OBTENIDOS DE MUESTRAS DE SUELO

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    Fabián Galvis

    2014-01-01

    Full Text Available Bacillus thuringiensis es una bacteria Gram-positiva formadora de esporas, que produ - ce cristales parasporales de naturaleza proteica, tóxicos contra diferentes órdenes de insectos y biodegradables e inocuos para otras especies. Esta investigación empleó el modelo experimen - tal, que mediante técnicas de observación permi - tió, la identificación microbiológica y bioquímica de B. thuringiensis a partir de muestras de suelo de los municipios de Cúcuta, El Zulia, Los Patios, San Cayetano y Villa del Rosario, Norte de Santander, Colombia, y su posterior caracteri - zación con los marcadores moleculares Bc-Rep y MB1. Se identificaron microbiológica y bioquí - micamente 10 aislados como B. thuringiensis ; los resultados del análisis filogenético mostraron diferencias significativas en los agrupamientos obtenidos con los marcadores Bc-Rep y MB1. Con Bc-Rep se registró un índice de similaridad bajo (18%, mientras que con el marcador MB1 se obtuvo un índice mayor de similitud, 58%. En este trabajo se evidenció una gran variabilidad genética entre los aislados, que mostraron a los marcadores Bc-Rep y MB1 como altamente efectivos para diferenciar cepas estrechamente relacionadas, convirtiéndose en una herramienta genética de gran valor para estudios de identifi-cación y diversidad en B. thuringiensis.

  18. GENOTYPING OF SALMONELLA STRAINS ISOLATED FROM DUCKS AND THEIR ENVIRONMENTS IN PENANG, MALAYSIA USING REPETITIVE EXTRAGENIC PALINDROMIC (REP

    Directory of Open Access Journals (Sweden)

    Frederick Adzitey

    2013-08-01

    Full Text Available Salmonella are important foodborne pathogens of worldwide concern. The objective of this study was to determine the genetic diversity of 107 Salmonella strains isolated from ducks, their rearing and processing environments in Penang, Malaysia using repetitive extragenic palindromic-polymerase chain reaction (REP-PCR. REP-PCR of the Salmonella strains produced DNA bands of different sizes for differentiation purposes. The DNA band sizes ranged from 105-7692 bp for S. Typhimurium, 116-7033 bp for S. Hadar, 127-7399 bp for S. Enteritidis, 140-7497 bp for S. Braenderup and 123-5857 bp for S. Albany. Cluster analysis at a coefficient of 0.85 grouped the Salmonella strains into various clusters and singletons. S. Typhimurium were grouped into 4 clusters and 26 singletons at a discriminatory index (D-value of 0.98, S. Hadar were grouped into 3 clusters and 13 singletons at a D-value of 0.914, S. Enteritidis were grouped into 3 clusters and 9 singletons at a D-value of 0.971, S. Braenderup were grouped into 2 clusters and 11 singletons at a D-value of 0.981, and S. Albany were grouped into 3 clusters and 7 singletons at a D-value of 0.978. With the exception of S. Hadar strains which were grouped into two major groups (genotypes by REP-PCR, the rest were grouped into three major genotypes. REP-PCR successfully typed all the Salmonella strains and proved to be a useful typing tool for determining the genetic diversity of the duck Salmonella strains. Determining the genetic diversity among Salmonella strains, other foodborne pathogens and their sources of isolation is important to trace their primary or potential sources and the sources of human infection.

  19. Operación Sonrisa República Dominicana: 8 años de una intensa y positiva experiencia

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    Fernando De La Cruz-Acosta

    2016-03-01

    Full Text Available El objetivo de este artículo es dar a conocer el trabajo que, desde hace 8 años, está realizando un grupo de cirujanos plásticos perteneciente a la Fundación Operación Sonrisa República Dominicana a favor de los pacientes con malformaciones congénitas faciales, especialmente labio leporino y fisura palatina.

  20. [Optimization of the REP-PCR molecular classification method of Salmonella and its application in drug-resistant strains].

    Science.gov (United States)

    Wang, Chuan; Yu, Qian; Ma, Liya; Zhang, Chaowu; Pei, Xiaofang; Liu, Hengchuan

    2009-11-01

    To optimize the reaction conditions of REP-PCR molecular classification method of Salmonella; primarily apply it in drug-resistant strains, and supply data to a system of Salmonella homology tracing. Genomic DNA of Salmonella enteritidis 510041 was used as the template for PCR. Target sequences in 510041 genomic DNA were amplified with the primers designed according to the references. To optimize template concentration, Mg2+ concentration, primers concentration of PCR, the factor to be optimized was designed in different concentration grads and other factors were fixed. The REP-PCR fingerprint maps of 24 strains of Salmonella epidemic drug-resistant isolates were analyzed with the optimum reaction conditions. The 24 strains of Salmonella epidemic drug-resistant isolates were classified according to their fingerprint maps, and the classification results were compared to classification results form drug-resistant spectrum. The fingerprint map bands were most clear when 25 microl of the reaction system contained 100 ng template, 2.0 mmol/L Mg2+ and 0.4 micromol/L each primer. The REP-PCR fingerprint maps of different serotypes and serum clusters of Salmonella were different. The amplification products contained 2 to 6 bands, whose length were between 0.5 kb to 2.5 kb. The 24 strains of Salmonella isolates were classified in 15 types according to fingerprint maps and 7 types according to drug-resistant spectrum. The optimum REP-PCR molecular classification method of Salmonella was established fingerprint maps classification method was more sensitive than drug-resistant spectrum classification method.

  1. La Segunda República Española: Acción y omisión en materia electoral

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    Enrique Cebrián Zazurca

    2016-01-01

    Full Text Available : El artículo realiza un recorrido por la normativa electoral vigente en la Segunda República Española; presenta las características principales de las distintas normas, resaltando los elementos del régimen electoral republicano. Una vez conocido el régimen, se abordan las principales claves del sistema electoral de la República concebido globalmente. Finalmente, el artículo pone en relación el sistema electoral con el sistema de partidos, tratando de valorar si aquel influyó en la crisis de la República. El trabajo sostiene que en la Segunda República Española no se aprobó nunca una ley electoral que pudiera considerarse como verdaderamente republicana.

  2. Revolución versus reforma educativa en la segunda república española. Elementos de ruptura

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    Juan Manuel FERNÁNDEZ SORIA

    2010-03-01

    Full Text Available RESUMEN: Están fuera de toda duda las conexiones existentes entre la República de 1931-35 y la de 1936-39. En este sentido estamos de acuerdo con quienes afirman que el estallido de la guerra del 36 es el resultado de un proceso que arranca del mismo año en que se proclama la II República, iniciándose ya entonces —como sostiene Andrés M. Kramer— la «mecánica de guerra civil». La educación republicana en tiempo de guerra no puede quedar fuera de esta consideración, porque aquélla sumerge sus cimientos más profundos en la política educativa de 1931-35. Efectivamente, muchas de las acciones educativas y culturales llevadas a cabo durante la guerra no tendrían fácil explicación si no se examina previamente la tarea de la República del 31 en estos mismos aspectos.

  3. El Ecoturismo en los Humedales: Análisis de las Potencialidades de República Dominicana

    Directory of Open Access Journals (Sweden)

    Francisco Orgaz Agüera

    2014-04-01

    Full Text Available El turismo se configura como uno de los principales motores económicos de República Dominicana. En este sentido, el turismo de sol y playa es la principal tipología turística en el país. Aunque, República Dominicana cuenta con numerosas potencialidades turísticas para poner en marchas nuevas formas de turismo: Turismo gastronómico, turismo ornitológico, turismo cultural, ecoturismo, etc. El principal objetivo de esta investigación es analizar las potencialidades existentes en República Dominicana para desarrollar el ecoturismo en las zonas de humedales. La metodología ha consistido en un trabajo de campo, a través de las entrevistas, los grupos de discusión y la observación participante. Los resultados muestran las grandes potencialidades que tiene el país para desarrollar el ecoturismo en los humedales, y contribuir así, al desarrollo socioeconómico de las comunidades locales. 

  4. The RXL motif of the African cassava mosaic virus Rep protein is necessary for rereplication of yeast DNA and viral infection in plants

    Energy Technology Data Exchange (ETDEWEB)

    Hipp, Katharina; Rau, Peter; Schäfer, Benjamin [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany); Gronenborn, Bruno [Institut des Sciences du Végétal, CNRS, 91198 Gif-sur-Yvette (France); Jeske, Holger, E-mail: holger.jeske@bio.uni-stuttgart.de [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany)

    2014-08-15

    Geminiviruses, single-stranded DNA plant viruses, encode a replication-initiator protein (Rep) that is indispensable for virus replication. A potential cyclin interaction motif (RXL) in the sequence of African cassava mosaic virus Rep may be an alternative link to cell cycle controls to the known interaction with plant homologs of retinoblastoma protein (pRBR). Mutation of this motif abrogated rereplication in fission yeast induced by expression of wildtype Rep suggesting that Rep interacts via its RXL motif with one or several yeast proteins. The RXL motif is essential for viral infection of Nicotiana benthamiana plants, since mutation of this motif in infectious clones prevented any symptomatic infection. The cell-cycle link (Clink) protein of a nanovirus (faba bean necrotic yellows virus) was investigated that activates the cell cycle by binding via its LXCXE motif to pRBR. Expression of wildtype Clink and a Clink mutant deficient in pRBR-binding did not trigger rereplication in fission yeast. - Highlights: • A potential cyclin interaction motif is conserved in geminivirus Rep proteins. • In ACMV Rep, this motif (RXL) is essential for rereplication of fission yeast DNA. • Mutating RXL abrogated viral infection completely in Nicotiana benthamiana. • Expression of a nanovirus Clink protein in yeast did not induce rereplication. • Plant viruses may have evolved multiple routes to exploit host DNA synthesis.

  5. Platão e a poesia na República

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    Maria da Penha Villela-Petit

    2003-06-01

    Full Text Available Platão não é o iniciador, e sim o herdeiro da "velha divergência" entre filósofos e poetas. A motivação ético-teológica, que já animava Xenófanes,vai se reatualizar na República. Para poder apreciar o sentido dessa reatualização, importa que não se considere o Livro X isoladamente, mas se atente para os primeiros livros do diálogo. Neles, e com vistas a uma melhor determinação do justo -que é o que está em pauta-, Platão mostra a necessidade de se discutir as afirmações dos poetas. Trata-se assim de destituí-los da autoridade de que ainda gozam na educação e na opinião comum. Só graças à discussão filosófica e a uma educação por ela inspirada -o que pressupõe a produção ou a seleção de mitos- é que se pode esperar uma maior realização da justiça, tanto no plano do indivíduo (do governo de sua alma quanto no nível da cidade. A leitura aqui proposta das "razões" de Platão na República não impede que reconheçamos a importância da tragédia para a compreensão da existência humana, inclusive no que toca à idéia do divino.Plato is not the initiator, but rather the heir of the "old quarrel", between philosophers and poets. The ethical and theological motivation that drove Xenophanes is brought to date in the Republic. In order to realize that, one must take into account the whole of the dialogue - where the definition of justice is at stake - and, more precisely, its first books. There, Plato shows how important it is to put the poets' claims to question. The point is, after all, to deprive them of the authority they enjoy in what concerns educational matters as well as with public opinion. It is only through an education which is inspired by philosophical questioning - which also implies the production and selection of myths - that one can expect more justice both on the individual (the gouvernment of his soul and on the city levels. The reading we propose of Plato's "reasons" in the Republic does

  6. Safety and efficacy of REP 2139 and pegylated interferon alfa-2a for treatment-naive patients with chronic hepatitis B virus and hepatitis D virus co-infection (REP 301 and REP 301-LTF): a non-randomised, open-label, phase 2 trial.

    Science.gov (United States)

    Bazinet, Michel; Pântea, Victor; Cebotarescu, Valentin; Cojuhari, Lilia; Jimbei, Pavlina; Albrecht, Jeffrey; Schmid, Peter; Le Gal, Frédéric; Gordien, Emmanuel; Krawczyk, Adalbert; Mijočević, Hrvoje; Karimzadeh, Hadi; Roggendorf, Michael; Vaillant, Andrew

    2017-12-01

    REP 2139 clears circulating hepatitis B virus (HBV) surface antigen (HBsAg), enhancing the restoration of functional control of HBV infection by immunotherapy. We assessed the safety and efficacy of REP 2139 and pegylated interferon alfa-2a in patients with chronic HBV and hepatitis D virus (HDV) co-infection. In this open-label, non-randomised, phase 2 trial, patients aged 18-55 years, who were treatment naive, hepatitis B e antigen [HBeAg] negative, anti-hepatitis D antigen [HDAg] positive, and HDV RNA positive, with serum HBsAg concentrations of more than 1000 IU/mL, and a history of HDV infection for 6 months or more before treatment, were recruited at Toma Ciorbă Hospital of Infectious Diseases in Chișinău, Moldova. Patients were excluded if they had HDV superinfection, liver infections other than HBV and HDV, or liver cirrhosis. Patients received 500 mg intravenous REP 2139 once per week for 15 weeks, followed by combined therapy with 250 mg intravenous REP 2139 and 180 μg subcutaneous pegylated interferon alfa-2a once per week for 15 weeks, then monotherapy with 180 μg pegylated interferon alfa-2a once per week for 33 weeks. The primary endpoints assessed at the end of treatment were the safety and tolerability of the treatment regimen, analysed in the intention-to-treat population. Secondary outcomes included the proportion of patients with serum HBsAg less than 50 IU/mL, the proportion of patients with suppressed HBV DNA, and the proportion of patients who maintained these responses through follow-up. The REP 301 trial is registered with ClinicalTrials.gov, number NCT02233075. We also did an additional follow-up at 1 year after the end of treatment, as an interim analysis of the REP 301-LTF trial (planned duration 3 years), registered with ClinicalTrials.gov, number NCT02876419, which is ongoing but not recruiting patients. Between Sept 8, 2014, and Jan 27, 2015, we enrolled 12 patients into the REP 301 study. All 12 patients experienced at least one

  7. Childhood Cancer Statistics

    Science.gov (United States)

    ... Financial Reports Watchdog Ratings Feedback Contact Select Page Childhood Cancer Statistics Home > Cancer Resources > Childhood Cancer Statistics Childhood Cancer Statistics – Graphs and Infographics Number of Diagnoses ...

  8. Hacia una república conservadora : el programa político del Partido Agrario Español

    Directory of Open Access Journals (Sweden)

    Luis Teófilo Gil Cuadrado

    2005-01-01

    Full Text Available El Partido Agrario Español (PAE, fundado en enero de 1934 y presidido por José Martínez de Velasco, representó, dentro de la II República española, una alternativa conservadora y, al tiempo, leal al régimen. El programa político del PAE aceptaba la República —a diferencia de otros partidos derechistas del momento, como la CEDA y los monárquicos— y defendía la unidad nacional, el establecimiento de una segunda Cámara legislativa, la protección de la agricultura y la industria mediante aranceles, el libre comercio dentro de las fronteras nacionales y la revisión de algunas leyes del primer bienio como la Reforma Agraria de 1932. El objetivo era la configuración de una República conservadora distinta, en aspectos fundamentales, a la diseñada por la Constitución de 1931 y la legislación del bienio social-republicano.The Spanish Agrarian Party (Partido Agrario Español, PAE, founded in january of 1934 and presided by José Martínez de Velasco, was, in the political life of the Spanish Second Republic, a conservative and republican option. The agrarian program accepted the republican regime —in opposition to other conservative parties, like the CEDA or the monarchists— and defended the national union, the establishment of a Senate, the protection of the national agriculture and industry trough tariffs, the free trade in the Spanish market and the revision of some laws voted in the first biennium like the Agrarian Reform, promulgated in 1932. The idea was to establish a conservative Republic, different, in some fundamental aspects, of the regime designed by the Constitution of 1931 and the legislation approved during the socialist-republican biennium.

  9. La Primera línea de la Falange contra la República

    Directory of Open Access Journals (Sweden)

    José Antonio Parejo Fernández

    2005-01-01

    Full Text Available Partido de retaguardia, reunión de emboscados, así fue como al poco tiempo comenzó a ser vista la Falange por sus propios socios. Emboscados, en principio, lo fueron aquellos individuos, malos españoles en el imaginario colectivo de la derecha reaccionaria, que pudieron luchar contra la República y no lo hicieron. En la práctica, sin embargo, dicho calificativo respondió a un sentimiento muy concreto que se extendió por buena parte de la España Nacional y que vino a identificar a aquellos malos patriotas con los falangistas de la retaguardia. Así, mientras aquellos oportunistas conspiraban a salvo de las balas para imponer su modelo de estado totalitario y excluyente, en los frentes de batalla y a decir de los reaccionarios luchaban muchos españoles con nobleza y elevación de espíritu. Las continuas concentraciones, los desfiles, las misas al aire libre, los rituales nocturnos de antorchas protagonizadas por la Falange, aquella acusación, sin duda legítima a tenor de todo esto, se apoyó, no obstante, en una percepción torcida de la realidad.Ambushed, in principle, they were it who they could fight against the Republic and they didn’t make it. In the practice, however, that epithet was used by the reactionary right to attack the falangists of the rearguard. According to the reactionaries, while those opportunists conspired safe of the bullets to impose their model of totalitarian state, in the battle fronts many Spaniards fought with nobility and spirit elevation. The continuous concentrations, the parades, the religious rituals outdoors, the night rituals of brands played by the Falange, that accusation leaned on, nevertheless, in a bent perception of the reality. With this article, therefore, and using unpublished documental sources, we want to analyze the contribution of a Falange that became a fundamental pillar for the overthrow of the Second Spanish Republic in very little time.

  10. A natureza dos números na República de Platão

    Directory of Open Access Journals (Sweden)

    Anastácio Borges de Araújo Jr.

    2010-12-01

    Full Text Available É incontestável a presença das matemáticas nos diálogos de Platão, todavia o alcance e o sentido desta presença é matéria de controvérsia entre os especialistas. Alguns acreditam que os temas matemáticos empregados nos diálogos são fantasias matemáticas, outros defendem baseados, sobretudo no testemunho de Aristóteles, que Platão teria substituído na sua hipótese as formas inteligíveis pelos números ideais. Sem tomar partido de antemão nestas querelas, o que propomos aqui é uma investigação acerca da natureza dos números fundamentada exclusivamente nos textos de Platão, particularmente orientada por uma passagem do livro VII do diálogo República(525 b11- c3, em que Sócrates diz o seguinte: "Seria, portanto, conveniente colocar este estudo, ò Glaucon, dentro de uma legislação e persuadir aqueles que vão participar das grandes coisas na cidade a irem ao cálculo e a aplicarem-se a ele, não nos seus afazeres privados, mas até chegarem à contemplação da natureza dos números através da própria intelecção (...".The presence of the mathematics in Plato's dialogues is unquestionable. However, its reach and sense is controversial for some specialists. Some believe that the mathematical themes employed in the dialogues are mathematical fantasies; on the other hand, others defend, based on the Aristotle's testimonies, that Plato would have substituted the intelligible forms by the ideal numbers in his hypothesis. Having not taken part in the quarrel, we propose an investigation on the nature of the numbers based exclusively in Plato's texts, particularly oriented by the a passage in book VII of Republic (525 b11 - c3, in which Socrates says: "Then it would be fitting, Glaucon, to set this study down in law and persuade those who are going to participate in the greatest things in the city to go to calculation and to take it up, not after the fashion of private men, but stay with it until they come to the

  11. Proyectos de parcelas con servicios desarrollados por el INVI en la República Dominicana

    Directory of Open Access Journals (Sweden)

    Pou Howley, Carlos

    1984-07-01

    Full Text Available Santo Domingo, the capital of the Dominican Republic, has not escaped the phenomenon of urban growth and the concentration of large slum areas or hovels, mainly due to the migratory movements of the peasants who have been driven from the country. As a viable solution to the enormous problem of housing in this city, INVI, with the participation of the World Bank, is putting forward projects for lots supplied with services in which infrastructure services are installed on urban land and plots or parcels of land are given to families so that they can build or complete their houses. These projects are located in places registering a greater tendency towards development. The urban plan formulated in both projects is of an eminently pedestrian nature with a reduced thoroughfare for vehicles. In the pedestrian precinct, it was possible to lay down what have been called mini-parks, which involve widening the pedestrian thoroughfare and, in addition to constituting green areas distributed throughout the projects, they also reinforce the idea of a neighbourhood. Because of the scope of the projects, a series of installations have been provided to maintain their own community services, as well as commercial and institutional ones, which are distributed strategically.Santo Domingo, capital de la República Dominicana, no ha escapado al fenómeno del crecimiento urbano y a la concentración de grandes tugurios o arrabales, debido principalmente a los movimientos migratorios de los campesinos expulsados del campo. Como una solución viable al gran problema de la vivienda de esta ciudad, el INVI, con la participación del Banco Mundial, plantea proyectos de parcelas con Servicios en los cuales se instalan servicios de infraestructura en tierras urbanas y se proporcionan parcelas o solares a familias para que éstas construyan o completen sus viviendas. Se ubican estos proyectos en sitios que acusan una mayor tendencia de desarrollo. El esquema urbano

  12. Galeguismo, agro e agrarismo na Galicia da II República

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    Cabo Villaverde, Miguel

    2009-12-01

    Full Text Available The Partido Galeguista (PG was created in December 1931 as the expression of Galician nationalism during the Second Republic (1931-1936. Prior to that, the Galician nationalists had been very influential in the cultural sphere but rather powerless from a political point of view. The PG regarded agriculture and peasantry as a priority, not only because of their objective importance in the Galician economy and society in the 1930s but also because they were seen as the bulwarks of the national identity. In fact, the characteristics, needs and paths of development of the Galician agrarian sector were usually defined as opposed to those of the rest of Spain. It is then understable that the PG tried to win the agrarian unions over, and that it is arguable that it had plenty of common features with the so-called Agrarian Parties in other European regions.

    O Partido Galeguista (PG foi creado en decembro de 1931 como expresión do nacionalismo galego durante a Segunda República (1931-1936. Con anterioridade, os nacionalistas galegos foron moi influíntes no eido cultural pero maiormente inoperantes dende o punto de vista político. O PG consideraba a agricultura e o campesiñado como unha prioridade, non só pola súa importancia obxectiva na economía e sociedade galegas dos anos trinta senón tamén porque eran vistos como os baluartes da identidade nacional. De feito, as características, necesidades e vías de desenvolvemento do sector agrario galego eran normalmente definidas en oposición ás do resto de España. É daquela comprensible que o PG tentase gañarse ás sociedades agrarias, e mesmo se pode afirmar que tiña moitos puntos en común cos chamados Partidos Agrarios doutras rexións europeas.

  13. Les revistes bilingües a la Tortosa de la II República

    Directory of Open Access Journals (Sweden)

    M. Carme Gombau Domingo

    2017-06-01

    Full Text Available Resum: Enmig d’un panorama periodístic escrit exclusivament en castellà, sorgeix el primer rotatiu escrit íntegrament en català a Tortosa: La Veu de Tortosa. El succeeix La Veu de la Comarca en la voluntat de «desvetllar la consciència catalanista de la comarca tortosina». Tots dos rotatius representen la introducció del regionalisme a les terres de l’Ebre i del catalanisme conservador, en una ciutat on predominaren els partits dinàstics espanyols durant la primera dècada del segle xx. Després del silenci de la dictadura primorriverista, apareix un setmanari homònim del de principis de segle com a plataforma de difusió d’un partit comarcal afí al de la Lliga Regionalista. En contrapartida, la revista Vida Tortosina, primer, i el quinzenari Acció, després, esdevenen els òrgans d’expressió d’Acció Catalana i representen un moderat nacionalisme d’esquerres. Regionalistes i nacionalistes pretenien fer front a la força política majoritària a Tortosa amb l’establiment de la ii República, els republicans marcel·linistes.   Paraules clau: terres de l’Ebre, premsa comarcal, catalanisme, actituds lingüístiques Abstract: In the middle of a journalistic circuit written exclusively in Spanish, comes the first newspaper written entirely in Catalan in the city of Tortosa: La Veu de Tortosa. This one is followed by La Veu de la Comarca which has the firm intention of «awake the Catalan consciousness of the district of Tortosa». Both newspapers represent the introduction of regionalism in Terres de l’ Ebre and the Catalan language in a zone dominated throughout the first decade of the twentieth century by Spanish dynastic parties. After the silence of the dictatorship of Primo de Rivera appears a homonymous weekly as a diffusion platform of a district party related to the Lliga Regionalista. In counterpart, the magazine Vida Tortosina first, and the biweekly Acció after, become organs of expression of Acci

  14. Estratigrafía del Cretácico Superior de la Cordillera Oriental de la República Dominicana

    OpenAIRE

    García-Senz, J.; Monthel, J.; Díaz de Neira, J.A.; Hernaiz Huerta, P. P.; Calvo Sorando, José Pedro; Escuder Viruete, J.

    2007-01-01

    La sucesión del Cretácico Superior de la Cordillera Oriental de la República Dominicana contiene cerca de 6 km de rocas volcanogénicas sedimentarias y volcánicas depositadas en un sistema de talud sobre el extinto arco volcánico del Cretácico Inferior. Está limitada por dos discordancias que permiten caracterizarla como una secuencia deposicional. La inferior es consecuencia de los procesos de disgregación gravitacional que acompañan la formación del talud submarino; la superior se debe a la ...

  15. Rep-PCR typing of Staphylococcus spp. strains in meat paste production line and identification of their origin

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    Ivan Manga

    2015-05-01

    Full Text Available A meat paste production line and its microbial parameters have been evaluated in single Czech company. The raw meat paste samples before heat treatment were tested positively for the presence of three staphylococci species: Staphylococcus aureus, Staphylococcus haemolyticus and Staphylococcus epidermidis. Subsequent microbial analysis of meat paste components and ingredients (fresh meat, water, spices, equipment identified only the spices used as positive for S. aureus (coriander, cinnamon, badian, mustard – (10 - 40 cfu/g and S. haemolyticus strains (juniper, ginger. The collection of sixteen collected strains (S. aureus (n = 4, S. haemolyticus (n = 4, S. epidermidis (n = 8 has been typed with the rep-PCR method utilising (GTG5 primer. Analysis of the fingerprints using the unweighted pair-group method using arithmetic averages (UPGMA clustering method revealed presence of eleven strain clusters with similarity lower than 90%: two fingerprint clusters of S. aureus, three individual clusters characteristic for S. haemolyticus and six different S. epidermidis specific clusters. The S. aureus strains from different types of spice were identical, resp. very similar. Molecular tracking composed from the rep-PCR analysis of acquired isolates and comparison among all collected fingerprints confirmed the spices to be the source of both S. aureus and S. haemolyticus strains identified in raw meat paste. The additional rep-PCR analysis of the S. epidermidis collection confirmed usability and performance of this method. The antibiotic susceptibility to fourteen individual antibiotics has been examined among the collected staphylococci strains. The predominant erythromycin resistance (68.8% was followed with the resistance to amoxicillin/clavulanic acid (56.2%. Other resistances observed were less frequent (clindamycin – 12.5%, oxacillin – 6.3%, tetracycline – 6.3%, sulphamethoxazole-trimethoprim – 6.3%, chloramphenicol – 6.3%, novobiocin – 6

  16. Un ministro para la Defensa de la República desde el exilio : Juan Hernández Saravia

    OpenAIRE

    Manuela Aroca Mohedano

    2004-01-01

    La nueva situación internacionai surgida tras el final de la II Guerra Mundial propició la recuperación de las instituciones republicanas españolas en el exilio. Juan Hernández Saravia, un militar profesional, azañista y republicano, será el ministro de la Defensa Nacional de la República Española. Entre posibilidades reales y utopías, a caballo entre la defensa a ultranza de la legalidad y la protección de los movimientos clandestinos antifranquistas, en medio de las disensiones de los milit...

  17. Liberalismo, iluminismo y romanticismo: el problema de la libertad en dos novelas de la República Restaurada

    OpenAIRE

    Verónica Hernández Landa Valencia

    2016-01-01

    El artículo propone una reflexión en torno a la forma como influyen tres corrientes de pensamiento, el liberalismo, el iluminismo y el romanticismo, en la representación del problema de la libertad en dos novelas históricas publicadas en la República Restaurada: Monja y casada, virgen y mártir, de Vicente Riva Palacio, y El pecado del siglo, de José Tomás de Cuéllar. Se busca mostrar que dichas corrientes se entrecruzan en un solo texto, que ello contribuye a la conformación de un concepto de...

  18. Virtud en La República de Platón y El Príncipe de Maquiavelo

    Directory of Open Access Journals (Sweden)

    Katherine Masís Iverson

    2014-11-01

    Full Text Available Desde el punto de vista de la ética de virtudes, el presente ensayo compara los filósofos-reyes de Platón con el príncipe de Maquiavelo. Primeramente, se define la ética de virtudes; seguidamente, se explica la manera en que se manifiesta la virtud en La República de Platón y El Príncipe de Maquiavelo. Finalmente, se valoran las semejanzas y diferencias entre ambos autores con respecto al concepto de virtud.

  19. Alguns ectoparasitas e protozoários em bovinos da República da Guiné-Bissau

    OpenAIRE

    Fernanda ROSA; Crespo, Maria Virgínia; Travassos Dias, J. A.

    1998-01-01

    Os autores assinalam a presença de algumas espécies de ixodídeos (Amblyomma variegatum, Boophilus annulatus, B. geigy e Hyalomma sp.) localizados em diferentes regiões do corpo de bovinos autóctones da República da Guiné-Bissau, colhidos entre Novembro de 1990 e Março de 1991. A pesquisa de protozoários, efectuada principalmente em esfregaços de sangue revelou a presença de Anaplasma marginale, Theileria mutans, Babesia bigemina e Sarcocystis sp. Não foram encontradas lesões relacionada...

  20. Experiencias de colaboradores tuneros en la República Democrática de Timor-Leste

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    Juana Magdalena Castro García

    2014-08-01

    Full Text Available En la presente comunicación breve se relatan las experiencias de una enfermera que se desempeñó profesionalmente en la asistencia médica y la docencia en la República Democrática de Timor Leste. A través de las vivencias compartidas se ponen de manifiesto los valores humanos que caracterizan al personal de la salud cubana, entre ellos: el humanismo, la responsabilidad, la laboriosidad y la solidaridad, características que muestran un ejemplo del papel de la mujer cubana en la Revolución

  1. Presentación : La intervención estadounidense de 1965 en la República Dominicana

    OpenAIRE

    Maffeo, Aníbal José

    2005-01-01

    En esta edición de Relaciones Internacionales, el Departamento de Historia de las Relaciones Internacionales ha preparado dos artículos referidos a la intervención. En uno de ellos se hace una breve reseña de la intervención, y las situaciones que llevaron a la creación de la FIT, así como se analizan los intereses norteamericanos en República Dominicana. El siguiente, se aboca a analizar los pormenores del conflicto y la intervención, analizándose además los beneficios y desventajas de la in...

  2. MQSA National Statistics

    Science.gov (United States)

    ... Standards Act and Program MQSA Insights MQSA National Statistics Share Tweet Linkedin Pin it More sharing options ... but should level off with time. Archived Scorecard Statistics 2018 Scorecard Statistics 2017 Scorecard Statistics 2016 Scorecard ...

  3. Production of recombinant AAV vectors encoding insulin-like growth factor I is enhanced by interaction among AAV rep regulatory sequences

    Directory of Open Access Journals (Sweden)

    Dilley Robert

    2009-01-01

    Full Text Available Abstract Background Adeno-associated virus (AAV vectors are promising tools for gene therapy. Currently, their potential is limited by difficulties in producing high vector yields with which to generate transgene protein product. AAV vector production depends in part upon the replication (Rep proteins required for viral replication. We tested the hypothesis that mutations in the start codon and upstream regulatory elements of Rep78/68 in AAV helper plasmids can regulate recombinant AAV (rAAV vector production. We further tested whether the resulting rAAV vector preparation augments the production of the potentially therapeutic transgene, insulin-like growth factor I (IGF-I. Results We constructed a series of AAV helper plasmids containing different Rep78/68 start codon in combination with different gene regulatory sequences. rAAV vectors carrying the human IGF-I gene were prepared with these vectors and the vector preparations used to transduce HT1080 target cells. We found that the substitution of ATG by ACG in the Rep78/68 start codon in an AAV helper plasmid (pAAV-RC eliminated Rep78/68 translation, rAAV and IGF-I production. Replacement of the heterologous sequence upstream of Rep78/68 in pAAV-RC with the AAV2 endogenous p5 promoter restored translational activity to the ACG mutant, and restored rAAV and IGF-I production. Insertion of the AAV2 p19 promoter sequence into pAAV-RC in front of the heterologous sequence also enabled ACG to function as a start codon for Rep78/68 translation. The data further indicate that the function of the AAV helper construct (pAAV-RC, that is in current widespread use for rAAV production, may be improved by replacement of its AAV2 unrelated heterologous sequence with the native AAV2 p5 promoter. Conclusion Taken together, the data demonstrate an interplay between the start codon and upstream regulatory sequences in the regulation of Rep78/68 and indicate that selective mutations in Rep78/68 regulatory elements

  4. Sampling, Probability Models and Statistical Reasoning Statistical ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 5. Sampling, Probability Models and Statistical Reasoning Statistical Inference. Mohan Delampady V R Padmawar. General Article Volume 1 Issue 5 May 1996 pp 49-58 ...

  5. [Influence of magnetic field on the growth of pathogen microorganisms isolated from the indoor environment at the Archivo Nacional de la República de Cuba].

    Science.gov (United States)

    Anaya, Matilde; Barbará, Eduardo; Padrón, Jesús; Borrego, Sofía F; Valdés, Oderlaise; Molina, Alian

    2015-01-01

    Electromagnetic pollution has been detected at the Archivo Nacional de la República de Cuba and the influence of extremely low frequency magnetic fields could be quantified with pathogenic microorganisms isolated from the indoor environment. To quantify the influence of an extremely low frequency magnetic field on the growth of pathogenic microorganisms isolated from the environment at the Archivo Nacional. We used five microorganisms isolated at the Archivo Nacional: Streptococcus sp. (1), Listeria sp. (2) and Candida guillermondii (3), and Escherichia coli ATCC 25922 (4) and Saccharomyces cerevisiae (5) as references. We applied this magnetic field of extremely low frequency, 60 Hz/220 V (3 mT), for two hours to these microorganisms on three culture tubes with distilled water and nutrient broth. Then we inoculated 0.1 mL in the following solid culture mediums on Petri dishes: CromoCen SC Agar (1 and 2), Potato Dextrose Agar (3), CromoCen DC 4227 (4) and Malt Extract Agar (5). The colonies were counted (log CFU/mL) by digital processing of the images of Petri dishes using the MatLab ® tool. We observed a statistically significant stimulation (p=0.05) in the quantity of treated colonies as compared to controls, which was higher in nutrient broth than in distilled water, and in bacteria (nutrient broth and treated colonies: 9.43 to 10.62 CFU/mL) as compared with yeasts (nutrient broth-treated colonies: 8.31 to 8.79 CFU/mL). In decreasing order, stimulation was as follows: Listeria sp., E. coli ATCC 25922, Streptococcus sp., C. guillermondii and S. cerevisiae . We concluded that the magnetic field applied had a stimulating effect on the microorganisms under study, which increases the risk to the health of staff and visitors at the Archivo Nacional .

  6. El Gobierno de la República en el exilio : crónica de un imposible retorno

    Directory of Open Access Journals (Sweden)

    Xavier Flores

    2001-01-01

    Full Text Available El triunfo de los aliados en la Segunda Guena Mundial hizo que los republicanos españoles exiliados en 1939 concibiesen esperanzas de un inmediato retomo de la República a su país con el apoyo aliado. Con esta idea se reconstituyeron las instituciones de la República Española en el exilio en México D. R, en agosto de 1945. En este artículo se analiza el proceso de esa reconstitución y los sucesivos gobiernos que se sucedieron hasta la disolución de las instituciones en junio de 1977, después de un imposible retorno.The victory of the salles in the Second World war did that the Spanish republicans exiled in 1939 were conceiving hopes ofan immediate return ofthe Republic to his(its country with the allied support. With this idea there were re-constituted the institutions of the Spanish Republic in the exile in México D.F., in August, 1945. In this article there are analyzed the process of this reconstitution and the successive governments that happened up to the dissolution of the institutions in June, 1977, afíer impossible I come back.

  7. Adeno-associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Shuohao [Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395 (Japan); Kawabe, Yoshinori; Ito, Akira [Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395 (Japan); Kamihira, Masamichi, E-mail: kamihira@chem-eng.kyushu-u.ac.jp [Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395 (Japan); Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395 (Japan)

    2012-01-06

    Highlights: Black-Right-Pointing-Pointer Adeno-associated virus (AAV) is capable of targeted integration in human cells. Black-Right-Pointing-Pointer Integrase-defective retroviral vector (IDRV) enables a circular DNA delivery. Black-Right-Pointing-Pointer A targeted integration system of IDRV DNA using the AAV integration mechanism. Black-Right-Pointing-Pointer Targeted IDRV integration ameliorates the safety concerns for retroviral vectors. -- Abstract: Retroviral vectors have been employed in clinical trials for gene therapy owing to their relative large packaging capacity, alterable cell tropism, and chromosomal integration for stable transgene expression. However, uncontrollable integrations of transgenes are likely to cause safety issues, such as insertional mutagenesis. A targeted transgene integration system for retroviral vectors, therefore, is a straightforward way to address the insertional mutagenesis issue. Adeno-associated virus (AAV) is the only known virus capable of targeted integration in human cells. In the presence of AAV Rep proteins, plasmids possessing the p5 integration efficiency element (p5IEE) can be integrated into the AAV integration site (AAVS1) in the human genome. In this report, we describe a system that can target the circular DNA derived from non-integrating retroviral vectors to the AAVS1 site by utilizing the Rep/p5IEE integration mechanism. Our results showed that after G418 selection 30% of collected clones had retroviral DNA targeted at the AAVS1 site.

  8. Repérage d’Images Ordinaires : Analyse des Requêtes des Chercheurs d’Images

    Directory of Open Access Journals (Sweden)

    Elaine Ménard

    2009-06-01

    also emphasizes the pressing necessity to optimize the methods used for image processing, in order to facilitate image retrieval and dissemination in multilingual environments. Résumé Depuis quelques années, le web est devenu un média incontournable pour la diffusion de ressources multilingues. Cependant, les différences linguistiques constituent souvent un obstacle majeur aux échanges de documents scientifiques, culturels, pédagogiques et commerciaux. En plus de cette diversité linguistique, on constate le développement croissant de bases de données et de collections composées de différents types de documents textuels ou multimédias, ce qui complexifie également le processus de repérage documentaire. Par exemple, les collections d’images numériques sont aussi nombreuses que diversifiées. Le besoin de repérer une image spécifique dans diverses collections est devenu une préoccupation partagée par plusieurs communautés. La croissance du web a mis en relief le besoin pressant de se doter d’outils propres à la description des images dans le but de faciliter leur repérage, puisque l’on retrouve celles-ci dans la plupart des ressources disponibles. Cette recherche compare le repérage d’images dans deux contextes linguistiques différents : un contexte monolingue, c’est-à-dire que la langue de la requête (français est la même que la langue d’indexation (français; et un contexte multilingue où la langue de la requête (français est différente de la langue d’indexation (anglais. Cet article présente les résultats de l’analyse des requêtes formulées par les participants pour repérer un ensemble d’images ordinaires représentant des objets de la vie quotidienne, en contexte de repérage multilingue. L’examen des termes contenus dans les requêtes des chercheurs d’images révèle les tendances observées sur le plan terminologique, perceptuel et structurel. Les participants emploient généralement des requêtes simples

  9. Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158

    Science.gov (United States)

    Boer, D. Roeland; Ruiz-Masó, José Angel; Rueda, Manuel; Petoukhov, Maxim V.; Machón, Cristina; Svergun, Dmitri I.; Orozco, Modesto; Del Solar, Gloria; Coll, Miquel

    2016-02-01

    DNA replication initiation is a vital and tightly regulated step in all replicons and requires an initiator factor that specifically recognizes the DNA replication origin and starts replication. RepB from the promiscuous streptococcal plasmid pMV158 is a hexameric ring protein evolutionary related to viral initiators. Here we explore the conformational plasticity of the RepB hexamer by i) SAXS, ii) sedimentation experiments, iii) molecular simulations and iv) X-ray crystallography. Combining these techniques, we derive an estimate of the conformational ensemble in solution showing that the C-terminal oligomerisation domains of the protein form a rigid cylindrical scaffold to which the N-terminal DNA-binding/catalytic domains are attached as highly flexible appendages, featuring multiple orientations. In addition, we show that the hinge region connecting both domains plays a pivotal role in the observed plasticity. Sequence comparisons and a literature survey show that this hinge region could exists in other initiators, suggesting that it is a common, crucial structural element for DNA binding and manipulation.

  10. As letras de uma revolução: a implantação da república em Portugal a 5 de outubro de 1910

    Directory of Open Access Journals (Sweden)

    Ana Paula Pires

    Full Text Available Resumo A implantação da República portuguesa em 5 de outubro de 1910 culminou um processo que remonta ao final do século XIX e, em especial, aos seus últimos anos. Trata-se de um período de condensação de um contexto de crise multifacetada em que se inscreveu o colapso da Monarquia constitucional e o rasgo de um caminho, de certa forma inexorável, que conduziu à República. O texto analisa a preparação da Revolução e a implantação da República em Portugal.

  11. Transición demográfica y arreglos residenciales de los adultos mayores en República Dominicana y Argentina

    OpenAIRE

    Enrique PELÁEZ; Jafmary FÉLIZ-FERRERAS

    2010-01-01

    Este artículo describe y compara los arreglos residenciales de los adultos mayores en dos países que se encuentran en distintas etapas de transición demográfica: Argentina y República Dominicana. Las fuentes de información utilizadas fueron los microdatos censales de ambos países, boletines demográficos y el Sistema de Indicadores sobre Envejecimiento desarrollado por el FNUAP y Celade. El análisis del impacto de las diferencias de la transición demográfica entre Argentina y la República Domi...

  12. Modelo de ecuaciones estructurales para predecir el bienestar y la dependencia funcional en adultos mayores de la República Dominica

    OpenAIRE

    Oliver Germes, Amparo; Navarro Pardo, Esperanza; Meléndez Moral, Juan Carlos; Molina, Cristina; Tomás Miguel, José Manuel

    2009-01-01

    Objetivo. Generar un modelo estructural multifactorial que explique la dependencia funcional y el bienestar a partir de algunas características sociodemográficas asociadas con esos dominios, en adultos mayores de la República Dominicana. Métodos. Estudio transversal mediante encuesta en una muestra de 1397 personas de 65 años o más representativa de la población de adultos mayores de la República Dominicana. Se recabó información sociodemográfica de los entrevistados (sexo, edad, nivel de est...

  13. La educación a distancia en la República Dominicana: situación actual y desafíos futuros

    OpenAIRE

    Acosta Peralta, Mirian

    2013-01-01

    La educación a distancia, especialmente en el nivel superior, es una realidad de creciente importancia en la República Dominicana. La presente investigación sobre “La educación a distancia en la República Dominicana: Situación actual y desafíos futuros”, parte de la búsqueda de respuestas a la problemática creada por la falta de información sobre los fundamentos teóricos y filosóficos de la educación a distancia dominicana, el marco legal que regula su funcionamiento y asegu...

  14. La Segunda República Española: Acción y omisión en materia electoral

    OpenAIRE

    Enrique Cebrián Zazurca

    2016-01-01

    : El artículo realiza un recorrido por la normativa electoral vigente en la Segunda República Española; presenta las características principales de las distintas normas, resaltando los elementos del régimen electoral republicano. Una vez conocido el régimen, se abordan las principales claves del sistema electoral de la República concebido globalmente. Finalmente, el artículo pone en relación el sistema electoral con el sistema de partidos, tratando de valorar si aquel influyó en l...

  15. Examen de Auditoría Integral a la Dirección de Compras Públicas de la Vicepresidencia de la República

    OpenAIRE

    Balarezo Nuñez, Mariana de Jesus

    2014-01-01

    La auditoría integral practicada a la Dirección de Compras Públicas de la Vicepresidencia de la República del Ecuador se desarrolló considerando aspectos encaminados al análisis del control interno; al cumplimiento de las disposiciones legales, y demás normas aplicables en la entidad; y de las metas y objetivos propuestos; investigación que servirá de aporte para mejorar los sistemas de control administrativos y financieros de la Dirección de Compras Públicas de la Vicepresidencia de la Rep...

  16. Algebraic statistics computational commutative algebra in statistics

    CERN Document Server

    Pistone, Giovanni; Wynn, Henry P

    2000-01-01

    Written by pioneers in this exciting new field, Algebraic Statistics introduces the application of polynomial algebra to experimental design, discrete probability, and statistics. It begins with an introduction to Gröbner bases and a thorough description of their applications to experimental design. A special chapter covers the binary case with new application to coherent systems in reliability and two level factorial designs. The work paves the way, in the last two chapters, for the application of computer algebra to discrete probability and statistical modelling through the important concept of an algebraic statistical model.As the first book on the subject, Algebraic Statistics presents many opportunities for spin-off research and applications and should become a landmark work welcomed by both the statistical community and its relatives in mathematics and computer science.

  17. What are the statistics in statistical learning?

    Science.gov (United States)

    Holt, Lori L.; Lotto, Andrew J.

    2003-10-01

    The idea that speech perception is shaped by the statistical structure of the input is gaining wide enthusiasm and growing empirical support. Nonetheless, statistics and statistical learning are broad terms with many possible interpretations and, perhaps, many potential underlying mechanisms. In order to define the role of statistics in speech perception mechanistically, we will need to more precisely define the statistics of statistical learning and examine similarities and differences across subgroups. In this talk, we examine learning of four types of information: (1) acoustic variance that is defining for contrastive categories, (2) the correlation between acoustic attributes or linguistic features, (3) the probability or frequency of events or a series of events, (4) the shape of input distributions. We present representative data from online speech perception and speech development and discuss inter-relationships among the subgroups. [Work supported by NSF, NIH and the James S. McDonnell Foundation.

  18. Blood Facts and Statistics

    Science.gov (United States)

    ... Blood > Blood Facts and Statistics Blood Facts and Statistics Facts about blood needs Facts about the blood ... to Top Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells ...

  19. Adrenal Gland Tumors: Statistics

    Science.gov (United States)

    ... Gland Tumor: Statistics Request Permissions Adrenal Gland Tumor: Statistics Approved by the Cancer.Net Editorial Board , 03/ ... primary adrenal gland tumor is very uncommon. Exact statistics are not available for this type of tumor ...

  20. State transportation statistics 2009

    Science.gov (United States)

    2009-01-01

    The Bureau of Transportation Statistics (BTS), a part of DOTs Research and : Innovative Technology Administration (RITA), presents State Transportation : Statistics 2009, a statistical profile of transportation in the 50 states and the : District ...

  1. Neuroendocrine Tumor: Statistics

    Science.gov (United States)

    ... Tumor > Neuroendocrine Tumor: Statistics Request Permissions Neuroendocrine Tumor: Statistics Approved by the Cancer.Net Editorial Board , 11/ ... the body. It is important to remember that statistics on the survival rates for people with a ...

  2. The foundations of statistics

    CERN Document Server

    Savage, Leonard J

    1972-01-01

    Classic analysis of the foundations of statistics and development of personal probability, one of the greatest controversies in modern statistical thought. Revised edition. Calculus, probability, statistics, and Boolean algebra are recommended.

  3. Generalized Fractional Statistics

    OpenAIRE

    Kaniadakis, G.; A. Lavagno(Politecnico di Torino and INFN Sezione di Torino, Torino Italy); Quarati, P.

    1996-01-01

    We link, by means of a semiclassical approach, the fractional statistics of particles obeying the Haldane exclusion principle to the Tsallis statistics and derive a generalized quantum entropy and its associated statistics.

  4. Aliados, tránsfugas y barrilitos: las elecciones legislativas de 2010 en República Dominicana

    Directory of Open Access Journals (Sweden)

    Ana Belén BENITO SÁNCHEZ

    2011-03-01

    Full Text Available Este artículo analiza las claves explicativas de los resultados de las elecciones legislativas y municipales de 2010 en República Dominicana así como de la reciente transformación que ha experimentado el sistema de partidos dominicano, del tripartidismo al bipartidismo plural. El liderazgo del presidente Leonel Fernández, su imagen, popularidad y pragmatismo son la clave del éxito electoral del PLD, favorecido también por el faccionalismo endémico del PRD y la descomposición progresiva del PRSC. En esta contienda, el PLD consolida su dominio electoral gracias al apoyo de los partidos minoritarios y se asegura el control del Legislativo durante los próximos seis años.

  5. A questão da representação política na primeira república

    Directory of Open Access Journals (Sweden)

    Cristina Buarque de Hollanda

    Full Text Available O artigo trata o tema da representação política na Primeira República brasileira (1889-1930 a partir de três importantes matrizes de reflexão sobre a questão: o liberalismo, o positivismo e o realismo. Busca-se rejeitar a narrativa usual das primeiras décadas republicanas, baseada unicamente no diagnóstico de corrupção política, e iluminar outras faces importantes do cenário político da época. A despeito das diferenças significativas entre os modelos interpretativos em evidência, que constituem o cerne do artigo, eles convergem na expectativa de protagonismo do Estado na tarefa de unificação e criação do povo.

  6. Indalecio Prieto enjuicia el papel del Gobierno de la República en el estallido de la Guerra Civil

    Directory of Open Access Journals (Sweden)

    Antonio Marquina

    2006-10-01

    Full Text Available El documento que procedemos a transcribir es una grabación efectuada por Indalecio Prieto el 28 de marzo de 1961 en la casa de los esposos Rafael y Guillermina Supervía, en Washington. La grabación se puede dividir en cuatro partes. Una primera, de introducción, donde Prieto narra cómo fue invitado a México y el anhelo por volver a España de los republicanos exiliados. Luego la narración de los acontecimientos del 14 de abril con la instauración de la II República. El tercer apartado se refiere al pronunciamiento militar del 17 de julio, que enlaza con la última parte del documento relativa a la opinión de Prieto sobre Manuel Azaña.

  7. Alejandro Bunge y el problema de la vivienda obrera en la República Argentina (1910-1915

    Directory of Open Access Journals (Sweden)

    Jorge A. Núñez

    2010-02-01

    Full Text Available Este trabajo pretende indagar, a partir del estudio de la figura del economista Alejandro Bunge, en la problemática de la vivienda obrera en la República Argentina en las primeras décadas de la pasada centuria. Aquí se argumentará que los estudios realizados porAlejandro Bunge como director de la División Estadísticas del Departamento Nacional de Trabajo en el período 1910-1915 contribuyeron de manera notable a la elaboración del proyectoy posterior sanción de la Ley de Casas Baratas para Obreros (n°9677.

  8. La psicología en la república federal Alemana: situación actual de la disciplina

    Directory of Open Access Journals (Sweden)

    Edgar Heineken

    1979-01-01

    Full Text Available Se presentan datos sobre la situación actual de la psicología como ciencia y como profesión en la República Federal Alemana. Se muestra la distribución temática de las actividades de investigación y la dinámica de la comunicación científica, así como el número de estudiantes de psicología en los últimos años y la situación universitaria en lo que atañe al profesorado y estudiantado. Se explica además la situación de la psicología como profesión analizando la distribución de los psicólogos en las diferentes áreas profesionales.

  9. Co-producción de conocimiento en la integralidad. Montevideo: Universidad de la República

    Directory of Open Access Journals (Sweden)

    Cecilia Montes

    2015-11-01

    Full Text Available El libro Co-producción de conocimiento en la integralidad es organizado por el equipo docente de la Unidad de Apoyo a la Extensión y Actividades en el Medio (UAExAM de la Facultad de Psicología de la Universidad de la República (UdelaR. El proceso de producción del texto cuenta con un equipo de comité académico integrado por los Profesores Agregados Humberto Tommasino, Gabriel Kaplún y Gabriela Etchebehere. Además cuenta con un comité editor compuesto por los docentes asistentes, Javier Romano y Sandra Fraga, y la ayudante Valeria Cavalli. Ambos equipos realizan las revisiones para la selección de los artículos publicados.

  10. Utilisation of Rep-PCR to track microbes in aerosols collected adjacent to their source, a saline lake in Victoria, Australia.

    Science.gov (United States)

    Munday, Chris I; O'Loingsigh, Tadhg; Tapper, Nigel J; De Deckker, Patrick; Allison, Gwen E

    2013-04-15

    Dust storms are a major source of aerosolized bacteria, especially in the drought conditions experienced in Australia in the decade to 2009. The major aims of this project were to identify the culturable bacteria in environmental samples and to genetically fingerprint all isolates using repetitive element PCR (Rep-PCR) to investigate the possibility of tracking isolates from their source into the atmosphere. Four field trips were conducted to a dry lake in western Victoria, Australia to sample aerosols and sediments. Aerosols were collected at heights up to 150 m using vacuum pumps with filters attached to a tethered helium balloon, while corresponding sediments were collected in sterile polypropylene tubes. Isolates were cultivated on Tryptic Soy Agar, R2 Agar and Marine Agar, and grown in dark conditions at ambient temperature. By sequencing the 16S rRNA gene of 270 isolates, fifteen different bacterial families were identified, with both the aerosols and sediments dominated by the Bacillaceae family. Four sets of Rep-PCR primers were tested, with the ERIC and (GTG)5 primers proving to be the most suitable for fingerprinting the cultured taxa. Rep-PCR revealed very high strain diversity in the samples collected, however some strains were still able to be tracked from sediments up to 150 m in height. This shows the potential of Rep-PCR, however very large reference databases would be required for the technique to be more useful. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. Variation in extragenic repetitive DNA sequences in Pseudomonas syringae and potential use of modified REP primers in the identification of closely related isolates

    Directory of Open Access Journals (Sweden)

    Elif Çepni

    2012-01-01

    Full Text Available In this study, Pseudomonas syringe pathovars isolated from olive, tomato and bean were identified by species-specific PCR and their genetic diversity was assessed by repetitive extragenic palindromic (REP-PCR. Reverse universal primers for REP-PCR were designed by using the bases of A, T, G or C at the positions of 1, 4 and 11 to identify additional polymorphism in the banding patterns. Binding of the primers to different annealing sites in the genome revealed additional fingerprint patterns in eight isolates of P. savastanoi pv. savastanoi and two isolates of P. syringae pv. tomato. The use of four different bases in the primer sequences did not affect the PCR reproducibility and was very efficient in revealing intra-pathovar diversity, particularly in P. savastanoi pv. savastanoi. At the pathovar level, the primer BOX1AR yielded shared fragments, in addition to five bands that discriminated among the pathovars P. syringae pv. phaseolicola, P. savastanoi pv. savastanoi and P. syringae pv. tomato. REP-PCR with a modified primer containing C produced identical bands among the isolates in a pathovar but separated three pathovars more distinctly than four other primers. Although REP-and BOX-PCRs have been successfully used in the molecular identification of Pseudomonas isolates from Turkish flora, a PCR based on inter-enterobacterial repetitive intergenic concensus (ERIC sequences failed to produce clear banding patterns in this study.

  12. Hypersensitivity pneumonitis caused by Mycobacterium avium subsp. hominissuis in a hot tub, as proven by IS1245 RFLP and rep-PCR typing☆

    Directory of Open Access Journals (Sweden)

    Rianne J.C van der Zanden

    2012-01-01

    Full Text Available A symptomatic patient had repeatedly positive cultures of Mycobacterium avium subsp. hominissuis after exposure to a hot tub contaminated with M. avium subsp. hominissuis. The pulmonary and tub water isolates were indistinguishable by IS1245 RFLP as well as rep-PCR typing. Discontinued use of the hot tub resulted in culture conversion.

  13. Avances y desafíos en los regímenes electorales: América Central y República Dominicana

    Directory of Open Access Journals (Sweden)

    Hugo Picado León

    2015-01-01

    Full Text Available Este artículo resume los principales temas tratados en el Seminario Internacional Elecciones en América Central y República Dominicana. Se subraya el aporte de los organismos electorales en los procesos de transición a la democracia y sus principales desafíos en la actualidad

  14. [Valitsusliidus olevad Reformierakond ning Isamaa ja Res Publica Liit on kavandatava koolireformi suhtes eri meelt] / Mailis Reps, Tiiu Kuurme, Karin Kütt

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2010-01-01

    Reformierakonna ettepaneku kohta jätta omavalitsustele õiguse otsustada, kas gümnaasium ja põhikool lahutatakse või jätkatakse ühendkooliga avaldavad arvamust riigikogu liige Mailis Reps, Tallinna Ülikooli dotsent Tiiu Kuurme ja Rannu keskkooli direktor Karin Kütt

  15. Elecciones 2016 en República Dominicana: Características, desafíos y retos desde la perspectiva electoral

    Directory of Open Access Journals (Sweden)

    Roberto Rosario Márquez

    2015-01-01

    Full Text Available Expone la reforma electoral del año 2010, los aspectos importantes que se presentaron en las elecciones de 2012 y los retos que la Junta Central Electoral de la República Dominicana enfrenta en la organización y administración del proceso electoral del año 2016

  16. Un ministro para la Defensa de la República desde el exilio : Juan Hernández Saravia

    Directory of Open Access Journals (Sweden)

    Manuela Aroca Mohedano

    2004-01-01

    Full Text Available La nueva situación internacionai surgida tras el final de la II Guerra Mundial propició la recuperación de las instituciones republicanas españolas en el exilio. Juan Hernández Saravia, un militar profesional, azañista y republicano, será el ministro de la Defensa Nacional de la República Española. Entre posibilidades reales y utopías, a caballo entre la defensa a ultranza de la legalidad y la protección de los movimientos clandestinos antifranquistas, en medio de las disensiones de los militares exiliados dispersos en varios continentes, discurrirá la actuación de un Ministerio que tendrá como objetivo principal la recuperación del ejército para la futura restaurada República y que verá truncadas sus expectativas por la aparición en el panorama mundial de los primeros.A Minister in exile for tfie Republic Defence: Juan Hernández Saravia The new International situation arisen after the end of the Second World War led to the recovery of Spanish Republic Institutions in exile. Juan Hernández Saravia, an army officer, republican and adherent to Azaña, became the National Defence Minister of Spanish Republic. Among real possibilities and utopia, halfway between a vigorous legality defence and the protection of clandestino movements against Franco's dictatorship, the main objective of this Ministery was the army recovery for the futuro restoring Republic, but the early Cold War shattered these prospects.

  17. A comprehensive computational study on pathogenic mis-sense mutations spanning the RING2 and REP domains of Parkin protein.

    Science.gov (United States)

    Biswas, Ria; Bagchi, Angshuman

    2017-04-30

    Various mutations in PARK2 gene, which encodes the protein parkin, are significantly associated with the onset of autosomal recessive juvenile Parkinson (ARJP) in neuronal cells. Parkin is a multi domain protein, the N-terminal part contains the Ubl and the C-terminal part consists of four zinc coordinating domains, viz., RING0, RING1, in between ring (IBR) and RING2. Disease mutations are spread over all the domains of Parkin, although mutations in some regions may affect the functionality of Parkin more adversely. The mutations in the RING2 domain are seen to abolish the neuroprotective E3 ligase activity of Parkin. In this current work, we carried out detailed in silico analysis to study the extent of pathogenicity of mutations spanning the Parkin RING2 domain and the adjoining REP region by SIFT, Mutation Accessor, PolyPhen2, SNPs and GO, GV/GD and I-mutant. To study the structural and functional implications of these mutations on RING2-REP domain of Parkin, we studied the solvent accessibility (SASA/RSA), hydrophobicity, intra-molecular hydrogen bonding profile and domain analysis by various computational tools. Finally, we analysed the interaction energy profiles of the mutants and compared them to the wild type protein using Discovery studio 2.5. By comparing the various analyses it could be safely concluded that except P437L and A379V mutations, all other mutations were potentially deleterious affecting various structural aspects of RING2 domain architecture. This study is based purely on computational approach which has the potential to identify disease mutations and the information could further be used in treatment of diseases and prognosis. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Stan: Statistical inference

    Science.gov (United States)

    Stan Development Team

    2018-01-01

    Stan facilitates statistical inference at the frontiers of applied statistics and provides both a modeling language for specifying complex statistical models and a library of statistical algorithms for computing inferences with those models. These components are exposed through interfaces in environments such as R, Python, and the command line.

  19. Statistics using R

    CERN Document Server

    Purohit, Sudha G; Deshmukh, Shailaja R

    2015-01-01

    STATISTICS USING R will be useful at different levels, from an undergraduate course in statistics, through graduate courses in biological sciences, engineering, management and so on. The book introduces statistical terminology and defines it for the benefit of a novice. For a practicing statistician, it will serve as a guide to R language for statistical analysis. For a researcher, it is a dual guide, simultaneously explaining appropriate statistical methods for the problems at hand and indicating how these methods can be implemented using the R language. For a software developer, it is a guide in a variety of statistical methods for development of a suite of statistical procedures.

  20. Statistics For Dummies

    CERN Document Server

    Rumsey, Deborah

    2011-01-01

    The fun and easy way to get down to business with statistics Stymied by statistics? No fear ? this friendly guide offers clear, practical explanations of statistical ideas, techniques, formulas, and calculations, with lots of examples that show you how these concepts apply to your everyday life. Statistics For Dummies shows you how to interpret and critique graphs and charts, determine the odds with probability, guesstimate with confidence using confidence intervals, set up and carry out a hypothesis test, compute statistical formulas, and more.Tracks to a typical first semester statistics cou

  1. Industrial statistics with Minitab

    CERN Document Server

    Cintas, Pere Grima; Llabres, Xavier Tort-Martorell

    2012-01-01

    Industrial Statistics with MINITAB demonstrates the use of MINITAB as a tool for performing statistical analysis in an industrial context. This book covers introductory industrial statistics, exploring the most commonly used techniques alongside those that serve to give an overview of more complex issues. A plethora of examples in MINITAB are featured along with case studies for each of the statistical techniques presented. Industrial Statistics with MINITAB: Provides comprehensive coverage of user-friendly practical guidance to the essential statistical methods applied in industry.Explores

  2. Statistics for Finance

    DEFF Research Database (Denmark)

    Lindström, Erik; Madsen, Henrik; Nielsen, Jan Nygaard

    Statistics for Finance develops students’ professional skills in statistics with applications in finance. Developed from the authors’ courses at the Technical University of Denmark and Lund University, the text bridges the gap between classical, rigorous treatments of financial mathematics...

  3. CMS Program Statistics

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CMS Office of Enterprise Data and Analytics has developed CMS Program Statistics, which includes detailed summary statistics on national health care, Medicare...

  4. Recreational Boating Statistics 2012

    Data.gov (United States)

    Department of Homeland Security — Every year, the USCG compiles statistics on reported recreational boating accidents. These statistics are derived from accident reports that are filed by the owners...

  5. Recreational Boating Statistics 2011

    Data.gov (United States)

    Department of Homeland Security — Every year, the USCG compiles statistics on reported recreational boating accidents. These statistics are derived from accident reports that are filed by the owners...

  6. Recreational Boating Statistics 2013

    Data.gov (United States)

    Department of Homeland Security — Every year, the USCG compiles statistics on reported recreational boating accidents. These statistics are derived from accident reports that are filed by the owners...

  7. Statistical data analysis handbook

    National Research Council Canada - National Science Library

    Wall, Francis J

    1986-01-01

    It must be emphasized that this is not a text book on statistics. Instead it is a working tool that presents data analysis in clear, concise terms which can be readily understood even by those without formal training in statistics...

  8. Mathematical and statistical analysis

    Science.gov (United States)

    Houston, A. Glen

    1988-01-01

    The goal of the mathematical and statistical analysis component of RICIS is to research, develop, and evaluate mathematical and statistical techniques for aerospace technology applications. Specific research areas of interest include modeling, simulation, experiment design, reliability assessment, and numerical analysis.

  9. National transportation statistics 2011

    Science.gov (United States)

    2011-04-01

    Compiled and published by the U.S. Department of Transportation's Bureau of Transportation Statistics (BTS), National Transportation Statistics presents information on the U.S. transportation system, including its physical components, safety record, ...

  10. Principles of applied statistics

    National Research Council Canada - National Science Library

    Cox, D. R; Donnelly, Christl A

    2011-01-01

    .... David Cox and Christl Donnelly distil decades of scientific experience into usable principles for the successful application of statistics, showing how good statistical strategy shapes every stage of an investigation...

  11. El derecho de prenda y la realización de la prenda en los códigos civiles de la república de chile y de la república de argentina que recogen los proyectos bello y velez sarsfield, respectivamente

    Directory of Open Access Journals (Sweden)

    Fausto Viale Salazar

    1988-12-01

    Full Text Available El presente trabajo tiene por finalidad efectuar un estudio comparativo de dos grandes proyectos de Código Civil en Latinoamérica del siglo XIX, cuales son los Proyectos Bello y Vélez Sarsfield, que se van a plasmar en los Códigos Civiles de la República de Chile y de la República Argentina, respectivamente, encuanto a algunos aspectos de su normatividad acerca del derecho de prenda y la realización de la misma.

  12. Ethics in Statistics

    Science.gov (United States)

    Lenard, Christopher; McCarthy, Sally; Mills, Terence

    2014-01-01

    There are many different aspects of statistics. Statistics involves mathematics, computing, and applications to almost every field of endeavour. Each aspect provides an opportunity to spark someone's interest in the subject. In this paper we discuss some ethical aspects of statistics, and describe how an introduction to ethics has been…

  13. The Production of Meanings on the Political Crisis in the Profissão Repórter Program

    Directory of Open Access Journals (Sweden)

    Kalliandra Quevedo Conrad

    2017-08-01

    Full Text Available We analyze the production of meanings on the Brazilian political crisis in Rede Globo’s television program Profissão Repórter. Based on the Critical Discourse Studies and Social Theory of Discourse, Fairclough (2016, we focus on the discursive strategies used by the program in its Political Crisis edition (04/06/2016. The use of categories of vocabulary analysis, interactive control and intertextuality allowed us to locate regionalizations of meanings that form a Workers Party (PT subject position, a worker subject position and a protester subject position. The Workers Party subject establishes an antagonistic relation with the protester subject and marks itself by conflict, tension and fear meanings. The protester subject is built by respect, education, defense of the motherland and fight against corruption meanings. The worker subject appears in an intermediate region, not linked to the protests. The discourse silences the meanings of "impeachment" and "coup", and, therefore, avoids addressing the complexity of the Brazilian political crisis. Analisamos a produção de sentidos sobre a crise política brasileira no programa Profissão Repórter, da Rede Globo. A partir dos Estudos Críticos do Discurso e da Teoria Social do Discurso, de Fairclough (2016, nos focamos nas estratégias discursivas utilizadas pelo programa na edição Crise Política (6/04/2016. O uso das categorias de análise de vocabulário, controle interacional e intertextualidade permitiu localizarmos regionalizações de sentido nas posições de sujeito petista, sujeito trabalhador e sujeito manifestante. O sujeito petista estabelece uma relação antagônica com o sujeito manifestante e é marcado pelos sentidos de conflito, tensão e medo. O sujeito manifestante é construído pelos sentidos de respeito, educação, defesa da pátria e luta contra a corrupção. O sujeito trabalhador aparece numa região intermediária, não sendo vinculado aos protestos. O discurso

  14. Nonparametric statistical inference

    CERN Document Server

    Gibbons, Jean Dickinson

    2010-01-01

    Overall, this remains a very fine book suitable for a graduate-level course in nonparametric statistics. I recommend it for all people interested in learning the basic ideas of nonparametric statistical inference.-Eugenia Stoimenova, Journal of Applied Statistics, June 2012… one of the best books available for a graduate (or advanced undergraduate) text for a theory course on nonparametric statistics. … a very well-written and organized book on nonparametric statistics, especially useful and recommended for teachers and graduate students.-Biometrics, 67, September 2011This excellently presente

  15. Business statistics for dummies

    CERN Document Server

    Anderson, Alan

    2013-01-01

    Score higher in your business statistics course? Easy. Business statistics is a common course for business majors and MBA candidates. It examines common data sets and the proper way to use such information when conducting research and producing informational reports such as profit and loss statements, customer satisfaction surveys, and peer comparisons. Business Statistics For Dummies tracks to a typical business statistics course offered at the undergraduate and graduate levels and provides clear, practical explanations of business statistical ideas, techniques, formulas, and calculations, w

  16. Head First Statistics

    CERN Document Server

    Griffiths, Dawn

    2009-01-01

    Wouldn't it be great if there were a statistics book that made histograms, probability distributions, and chi square analysis more enjoyable than going to the dentist? Head First Statistics brings this typically dry subject to life, teaching you everything you want and need to know about statistics through engaging, interactive, and thought-provoking material, full of puzzles, stories, quizzes, visual aids, and real-world examples. Whether you're a student, a professional, or just curious about statistical analysis, Head First's brain-friendly formula helps you get a firm grasp of statistics

  17. Statistics & probaility for dummies

    CERN Document Server

    Rumsey, Deborah J

    2013-01-01

    Two complete eBooks for one low price! Created and compiled by the publisher, this Statistics I and Statistics II bundle brings together two math titles in one, e-only bundle. With this special bundle, you'll get the complete text of the following two titles: Statistics For Dummies, 2nd Edition  Statistics For Dummies shows you how to interpret and critique graphs and charts, determine the odds with probability, guesstimate with confidence using confidence intervals, set up and carry out a hypothesis test, compute statistical formulas, and more. Tra

  18. Statistics in a nutshell

    CERN Document Server

    Boslaugh, Sarah

    2013-01-01

    Need to learn statistics for your job? Want help passing a statistics course? Statistics in a Nutshell is a clear and concise introduction and reference for anyone new to the subject. Thoroughly revised and expanded, this edition helps you gain a solid understanding of statistics without the numbing complexity of many college texts. Each chapter presents easy-to-follow descriptions, along with graphics, formulas, solved examples, and hands-on exercises. If you want to perform common statistical analyses and learn a wide range of techniques without getting in over your head, this is your book.

  19. Statistics for Research

    CERN Document Server

    Dowdy, Shirley; Chilko, Daniel

    2011-01-01

    Praise for the Second Edition "Statistics for Research has other fine qualities besides superior organization. The examples and the statistical methods are laid out with unusual clarity by the simple device of using special formats for each. The book was written with great care and is extremely user-friendly."-The UMAP Journal Although the goals and procedures of statistical research have changed little since the Second Edition of Statistics for Research was published, the almost universal availability of personal computers and statistical computing application packages have made it possible f

  20. La "Carta a los maestros" de Jules Ferry (1883 y el laicismo escolar de la IIIª República francesa

    Directory of Open Access Journals (Sweden)

    Juan Manuel FERNÁNDEZ SORIA

    2010-03-01

    Full Text Available RESUMEN: Partiendo del valor histórico —de lo que es una muestra su influencia en la política educativa de la Segunda República española— y de la proyección de su legado en nuestros días de la «Carta a los Maestros» (1883 del ministro francés de Instrucción Pública, Jules Ferry, este trabajo se acerca a la vida de su autor y a su política educativa para analizar luego con mayor profundidad los aspectos más sobresalientes del documento —que transcribimos en francés y castellano—, especialmente el laicismo escolar, como medio de establecer una escuela nacional y de fundación de la República, la defensa de la moral común y positiva, los modos y procedimientos —tanto directos como indirectos— de su enseñanza, así como el papel del maestro y del manual en la educación moral y cívica del futuro ciudadano. ABSTRACT: Starting with the historic value —of which it is an example its influence in the educational policy of the Second Republic— and with the influence that remains in our days, of the legate of the «Elementary Schoolteacher’s Letter», written by Jules Ferry, French minister of the Public Instruction, this piece of work approaches to its author’s life and to its educational policy in order to analyse later in greater detail the most relevant aspects of the document —which we reproduce in Spanish and French— specially the scholastic laicism as a way to establish a national school, and the foundation of the Republic, the defence of common and positive morality, the ways and procedures, both direct and indirect, of its teaching, and also the role of schoolteachers and the guide in the moral and civic education of the future citizens.

  1. Estimation and inferential statistics

    CERN Document Server

    Sahu, Pradip Kumar; Das, Ajit Kumar

    2015-01-01

    This book focuses on the meaning of statistical inference and estimation. Statistical inference is concerned with the problems of estimation of population parameters and testing hypotheses. Primarily aimed at undergraduate and postgraduate students of statistics, the book is also useful to professionals and researchers in statistical, medical, social and other disciplines. It discusses current methodological techniques used in statistics and related interdisciplinary areas. Every concept is supported with relevant research examples to help readers to find the most suitable application. Statistical tools have been presented by using real-life examples, removing the “fear factor” usually associated with this complex subject. The book will help readers to discover diverse perspectives of statistical theory followed by relevant worked-out examples. Keeping in mind the needs of readers, as well as constantly changing scenarios, the material is presented in an easy-to-understand form.

  2. Lectures on algebraic statistics

    CERN Document Server

    Drton, Mathias; Sullivant, Seth

    2009-01-01

    How does an algebraic geometer studying secant varieties further the understanding of hypothesis tests in statistics? Why would a statistician working on factor analysis raise open problems about determinantal varieties? Connections of this type are at the heart of the new field of "algebraic statistics". In this field, mathematicians and statisticians come together to solve statistical inference problems using concepts from algebraic geometry as well as related computational and combinatorial techniques. The goal of these lectures is to introduce newcomers from the different camps to algebraic statistics. The introduction will be centered around the following three observations: many important statistical models correspond to algebraic or semi-algebraic sets of parameters; the geometry of these parameter spaces determines the behaviour of widely used statistical inference procedures; computational algebraic geometry can be used to study parameter spaces and other features of statistical models.

  3. Statistics for economics

    CERN Document Server

    Naghshpour, Shahdad

    2012-01-01

    Statistics is the branch of mathematics that deals with real-life problems. As such, it is an essential tool for economists. Unfortunately, the way you and many other economists learn the concept of statistics is not compatible with the way economists think and learn. The problem is worsened by the use of mathematical jargon and complex derivations. Here's a book that proves none of this is necessary. All the examples and exercises in this book are constructed within the field of economics, thus eliminating the difficulty of learning statistics with examples from fields that have no relation to business, politics, or policy. Statistics is, in fact, not more difficult than economics. Anyone who can comprehend economics can understand and use statistics successfully within this field, including you! This book utilizes Microsoft Excel to obtain statistical results, as well as to perform additional necessary computations. Microsoft Excel is not the software of choice for performing sophisticated statistical analy...

  4. Baseline Statistics of Linked Statistical Data

    NARCIS (Netherlands)

    Scharnhorst, Andrea; Meroño-Peñuela, Albert; Guéret, Christophe

    2014-01-01

    We are surrounded by an ever increasing ocean of information, everybody will agree to that. We build sophisticated strategies to govern this information: design data models, develop infrastructures for data sharing, building tool for data analysis. Statistical datasets curated by National

  5. National Statistical Commission and Indian Official Statistics

    Indian Academy of Sciences (India)

    T J Rao1. C. R. Rao Advanced Institute of Mathematics, Statistics and Computer Science (AIMSCS) University of Hyderabad Campus Central University Post Office, Prof. C. R. Rao Road Hyderabad 500 046, AP, India. Resonance – Journal of Science Education. Current Issue : Vol. 22, Issue 12 · Current Issue Volume 22 ...

  6. National Statistical Commission and Indian Official Statistics*

    Indian Academy of Sciences (India)

    IAS Admin

    Commission also stresses the importance of setting up of a. Methodological Study Unit to regularly undertake studies for bringing in improvements in the survey methodologies. The importance of a sound official statistical system in any country is well understood. Efficient governance depends largely on timely, accurate and ...

  7. Transición demográfica y arreglos residenciales de los adultos mayores en República Dominicana y Argentina

    Directory of Open Access Journals (Sweden)

    Enrique PELÁEZ

    2010-01-01

    Full Text Available Este artículo describe y compara los arreglos residenciales de los adultos mayores en dos países que se encuentran en distintas etapas de transición demográfica: Argentina y República Dominicana. Las fuentes de información utilizadas fueron los microdatos censales de ambos países, boletines demográficos y el Sistema de Indicadores sobre Envejecimiento desarrollado por el FNUAP y Celade. El análisis del impacto de las diferencias de la transición demográfica entre Argentina y la República Dominicana en la organización de la vida de las personas mayores es el objetivo principal de este estudio.

  8. La República Holandesa y su posición en el contexto colonial americano después de 1713

    Directory of Open Access Journals (Sweden)

    Crespo Solana, Ana

    2015-06-01

    Full Text Available During the War of Spanish Succession, the Dutch Republic fought alongside the Austrians and their allies against the Bourbon party. Still, and in spite of its alliance with England, the treaties of Utrecht did not leave the Dutch Republic in a good position. In this article, these treaties’ consequences for the commercial and colonial Dutch expansion in the Atlantic world are analyzed.Durante la guerra de Sucesión española, la República Holandesa luchó junto al bloque aliado austracista contra la opción borbónica. Sin embargo, y a pesar de su alianza con Inglaterra, la República Holandesa no salió bien restablecida de los tratados de Utrecht. En este artículo se analizarán las consecuencias que estos tratados tuvieron para la expansión comercial y colonial de Holanda en el Atlántico.

  9. Características de la Reforma del Estado en el Nivel Subnacional de la República Argentina

    Directory of Open Access Journals (Sweden)

    Horacio Cao

    1999-01-01

    Full Text Available Este trabajo tiene el objetivo de pasar revista a los principales condicionantes de los procesos de reforma del estado en el nivel subnacional de la República Ar gen tina. Para esto, se presenta una síntesis histórica que facilita la comprensión del federalismo en la Ar gen tina y se efectúa un análisis de los procesos de reforma del estado que se abren con la cri sis de mediados de los ‘70. Esta perspectiva examina las fuerzas contrapuestas que rodean a los Estados provinciales, en torno de la dicotomía reconversión/gobernabilidad. En términos de “reconversión”, las políticas tienden a relanzar las economías provinciales, en términos de “gobernabilidad” se desarrollan acciones cuyo objetivo es mantener la paz so cial, profundizando un perfil clientelar que mina los esfuerzos de reconversión.

  10. Nuevos registros de hongos entomopatógenos en acridios (Orthoptera: Acridoidea de la República Argentina

    Directory of Open Access Journals (Sweden)

    Sebastian A. PELIZZA

    2010-01-01

    Full Text Available Los acridios (tucuras y langostas continúan ocasionando pérdidas económicas en la agricultura a nivel mundial. En Argentina, la importancia de estos insectos ha sido reconocida desde mediados del siglo XIX, dependiendo de la región considerada y en relación al progresivo desarrollo agropecuario en el país. Los hongos son los microorganismos parásitos de insectos más frecuentemente encontrados en la naturaleza y la mayoría de las investigaciones con hongos entomopatógenos se ha centrado en su desarrollo como bioplaguicidas. En el presente trabajo se dan a conocer cinco registros nuevos de Beauveria bassiana (Bals.-Criv. Vuill., y dos de Entomophaga grylli (Fresen. A. Batko que se encontraron afectando distintas especies de acridios; se amplía así la distribución geográfica y el espectro hospedador para estas especies fúngicas. Cabe destacar que con el aporte de estos siete registros nuevos, el número total de hongos entomopatógenos de acridios citados para la República Argentina se eleva de 22 a 29.

  11. La sociedad civil movilizada y las reformas democráticas en la República Dominicana

    Directory of Open Access Journals (Sweden)

    Rosario Espinal

    2001-01-01

    Full Text Available En este artículo se identifican cinco periodos en el proceso de organización y movilización social que se produjo en la República Dominicana entre 1978 y 2000, el lapso más largo de apertura política que ha tenido el país. Se plantea que la naturaleza y la forma de estos movimientos ha variado como resultado de la situación económica, el partido en el poder, las estrategias de distintos gobiernos para ejercer control social sobre los grupos movilizados, el tipo de relación entre los partidos políticos y las organizaciones sociales y el financiamiento disponible para las organizaciones sociales. En cuanto al debate teórico sobre la relación entre movimientos sociales y democracia, se plantea que esta relación no es unívoca, y que en determinadas circunstancias los movimientos sociales pueden ayudar a la democratización y en otras a obstaculizarla

  12. Molecular epidemiology of SPM-1-producing Pseudomonas aeruginosa by rep-PCR in hospitals in Parana, Brazil.

    Science.gov (United States)

    Kalluf, K O; Arend, L N; Wuicik, T E; Pilonetto, M; Tuon, F F

    2017-04-01

    Infections caused by multidrug resistant microorganisms are a global health problem, and Pseudomonas aeruginosa is an important nosocomial pathogen, easily disseminated in the hospital environment. The aim of this study was to determine SPM-1 in P. aeruginosa strains in 30 Brazilian hospitals and the genetic similarity of isolates. We analyzed 161 isolates of carbapenem-resistant P. aeruginosa. Imipenem/EDTA and imipenem strip were used for phenotypic detection of MBL production; and real-time polymerase chain reaction (PCR) for genetic detection. Genetic similarity was determined by rep-PCR. We obtained 136/161 (84.5%) isolates with positive phenotypic result for metallo-β-lactamase (MBL) and the blaSPM-1 gene was identified in 41 isolates. There was a predominant profile (>95% of genetic similarity) in 92.7% of isolates. This predominant profile was widely disseminated in Paraná state. SPM-1 is the main MBL identified in carbapenem-resistant P. aeruginosa in Southern Brazil. The genetic similarity among some isolates suggests a clonal expansion. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Transpondo muros: Escritas da violência na República Democrática Alemã

    Directory of Open Access Journals (Sweden)

    Elcio Loureiro Cornelsen

    2009-06-01

    Full Text Available O objetivo do presente artigo é esboçar, a partir da interpretação das obras “Zeit-Zeugen”. Inhaftiert in Berlin-Hohenschönhausen (1996, organizada por Gabriele Camphausen, Folterzelle 36 Berlin-Pankow. Erlebnisbericht einer Stasihaft (1993, de Timo Zilli, Ein guter Kampf. Fakten, Daten, Erinnerungen 1945-1954 (1998 do político Ewald Ernst, Die Stasi war mein Eckermann: oder mein Leben mit der Wanze (1991, do escritor Erich Loest, e Geboren am 13. August. Der Sozialismus und ich (2004, do jornalista Jens Bisky, um breve estudo sobre as diversas formas e fases da violência enquanto instrumento de poder, praticada pelo Estado do SED na República Democrática Alemã nos 40 anos de sua existência, e discutir especialmente alguns aspectos teóricos sobre o conceito de “literatura de testemunho”. Os cinco relatos analisados, de caráter memorialista e autobiográfico, se pautam por um tom decididamente crítico frente aos desmandos num Estado totalitário. “Transpor muros” nos 20 anos após a Queda do Muro de Berlim, desse ponto de vista, implica um olhar memorialista de denúncia contra o esquecimento frente a um passado traumático.

  14. Evaluation of rep-PCR/DiversiLab versus PFGE and spa typing in genotyping methicillin-resistant Staphylococcus aureus (MRSA).

    Science.gov (United States)

    Aguadero, V; González Velasco, C; Vindel, A; Gonzalez Velasco, M; Moreno, J J

    2015-01-01

    Pulsed-field gel electrophoresis (PFGE) is the 'gold standard' for genotyping of methicillin-resistant Staphylococcus aureus (MRSA); however, the DiversiLab (DL) system, based on rep-PCR, is faster, simpler and could be better adapted to daily routine hospital work. We genotyped 100 MRSA isolates using PFGE, DL, and spa typing, and evaluated the discriminatory power of each technique and the correlation between them by Simpson's index(SI) and adjusted Rand coefficient (ARI), respectively. The isolates were from clinical samples from eight hospitals in Extremadura (Spain) during 2010. DL separated the 100 MRSA into 18 patterns, with 69% of the isolates grouped into four predominant patterns. spa typing reported 17 spa types, classifying 69% of MRSA into two major types (t067 and t002). PFGE revealed the existence of 27 patterns, gathering 54% of MRSA into three pulse types (E8a, E7a and E7b). SI values were 0.819, 0.726, 0.887 and 0.460 for DL, spa typing, PFGE and CC-BURP, respectively. ARI values of DL over PFGE, spa typing and CC-BURP were 0.151, 0.321 and 0.071, respectively. DL has less discriminatory power than PFGE but more than spa typing. The concordance of DL with PFGE is low, primarily because DL does not discriminate between the three predominant MRSA pulse types in our environment.

  15. La República Conservadora: ¿un mito en la historiografía nicaragüense?

    Directory of Open Access Journals (Sweden)

    Hugo Vargas González

    2011-08-01

    Full Text Available El artículo introduce una serie de reflexiones y sugiere al tiempo con base en la evidencia empírica que analiza a profundidad, una nueva periodización y eventual reconceptualización de uno de los períodos de la historia nicaragüense en apariencia más inamovibles como construcción social e historiográfica: el período de la “República Conservadora”, tradicionalmente situado entre 1858  y 1893. El autor da cuenta, de la forma en que la imagen de estabilidad política, armonía social y progreso económico endilgada socialmente a dicho período, y soportada  por el discurso historiográfico, se basa en premisas si no falsas al menos cuestionables, procedentes de los intereses legitimadores de un proyecto político específico, lo que ha obscurecido y a la vez obstaculizado el horizonte para nuevas interpretaciones y periodizaciones en la historia nicaragüense.

  16. República Democrática del Congo: ¿El campo estéril de los olivos?

    Directory of Open Access Journals (Sweden)

    Adriana María Ramírez López

    2010-11-01

    Full Text Available Los orígenes y las causas de la persistencia del conflicto en la República Democrática del Congo han sido explicados empleando argumentos simplificados que han tendido a minimizar la complejidad de los acontecimientos presentados en este país centroafricano desde la década de los noventa hasta el día de hoy. Estas explicaciones se caracterizan por su marcado carácter determinista y por ensombrecer aún más las perspectivas de paz de esta nación que se encuentra viviendo un coyuntural momento histórico. No obstante, una mirada más detallada al proceso de configuración del Estado poscolonial congoleño y a las dinámicas internacionales que han influido en su particular articulación pueden dar nuevas luces sobre el conflicto mismo, las causas de su prolongación y sus perspectivas de resolución.

  17. Felicidad subjetiva y autoeficacia docente en profesorado de República Dominicana y España

    Directory of Open Access Journals (Sweden)

    Teresa Mª Perandones González

    2013-12-01

    Full Text Available Este estudio analiza la relación entre los niveles de felicidad subjetiva y autoeficacia docente en una muestra de 454 docentes de todos los niveles educativos (desde Educación Infantil hasta la Universidad de República Dominicana y España. Para ello, se ha utilizado la Escala de Felicidad Subjetiva (Lyubomirsky y Lepper, 1999, que evalúa la felicidad general, y la Escala de Autoeficacia Docente (Tschannen-Moran y Woolfolk, 2001, la cual mide tres dimensiones: eficacia en el compromiso o la dedicación al estudiante, eficacia en las estrategias instruccionales, y eficacia en el manejo de la clase. Los resultados muestran correlaciones significativas y positivas entre las puntuaciones en felicidad subjetiva y las tres dimensiones de autoeficacia docente. Asimismo, la población dominicana obtiene puntuaciones más elevadas que la población española en todos los constructos analizados. En función de los resultados hallados, los cuales corroboran los de investigaciones previas en el ámbito de la Psicología Positiva (Seligman y Csikszentmihalyi, 2000, se propone la incorporación de planes formativos de educación emocional para el profesorado, puesto que la felicidad subjetiva, como parte de las emociones individuales, es un factor con altas implicaciones positivas para llevar a cabo con éxito los retos profesionales que plantea la tarea educativa.

  18. Os Anjos da Meia-Noite: trabalhadores, lazer e direitos no Rio de Janeiro da Primeira República

    Directory of Open Access Journals (Sweden)

    Leonardo Affonso de Miranda Pereira

    2013-12-01

    Full Text Available Em julho de 1913, os sócios do Club Dançante Familiar Anjos da Meia Noite requeriam ao Supremo Tribunal Federal um habeas corpus que lhes garantisse o direito de realizar bailes dançantes na região portuária do Rio de Janeiro. Era o fim de uma longa batalha jurídica por meio da qual os trabalhadores de baixa renda que compunham o clube, em sua maioria negros e mestiços, tentavam assegurar seus direitos recreativos. O faziam, porém, a partir de um tipo de associação cujos objetivos estavam distantes da lógica própria ao movimento operário do período. Acompanhar o caso, dando a ver seus antecedentes e lógicas, é, por isso, um meio de refletir sobre a imagem passiva projetada sobre os trabalhadores do Rio de Janeiro na Primeira República por parte da historiografia.

  19. The statistical stability phenomenon

    CERN Document Server

    Gorban, Igor I

    2017-01-01

    This monograph investigates violations of statistical stability of physical events, variables, and processes and develops a new physical-mathematical theory taking into consideration such violations – the theory of hyper-random phenomena. There are five parts. The first describes the phenomenon of statistical stability and its features, and develops methods for detecting violations of statistical stability, in particular when data is limited. The second part presents several examples of real processes of different physical nature and demonstrates the violation of statistical stability over broad observation intervals. The third part outlines the mathematical foundations of the theory of hyper-random phenomena, while the fourth develops the foundations of the mathematical analysis of divergent and many-valued functions. The fifth part contains theoretical and experimental studies of statistical laws where there is violation of statistical stability. The monograph should be of particular interest to engineers...

  20. Statistical Physics An Introduction

    CERN Document Server

    Yoshioka, Daijiro

    2007-01-01

    This book provides a comprehensive presentation of the basics of statistical physics. The first part explains the essence of statistical physics and how it provides a bridge between microscopic and macroscopic phenomena, allowing one to derive quantities such as entropy. Here the author avoids going into details such as Liouville’s theorem or the ergodic theorem, which are difficult for beginners and unnecessary for the actual application of the statistical mechanics. In the second part, statistical mechanics is applied to various systems which, although they look different, share the same mathematical structure. In this way readers can deepen their understanding of statistical physics. The book also features applications to quantum dynamics, thermodynamics, the Ising model and the statistical dynamics of free spins.

  1. El Ututo chaqueño Phyllopezus pollicaris (Spix 1825 (Squamata, Phyllodactylidae. Primer registro para la provincia de Jujuy (República Argentina

    Directory of Open Access Journals (Sweden)

    Burgos Gallardo, Freddy

    2013-01-01

    Full Text Available República Argentina, Jujuy; Departamento Santa Bárbara, Paraje Finca Fachine (23º 35' 55.98" S; 64º 13' 46.09" O 324 m s.n.m. Colector: Freddy Burgos. Depositado en la colección herpetológica del Laboratorio de Genética Evolutiva, Instituto de Biología Subtropical, UNaM-CONICET, Posadas, Misiones, Argentina. Macho adulto (LGE 02633.

  2. El poder local en la provincia de Albacete durante la II República y el intervencionismo del gobierno, 1931-1936

    Directory of Open Access Journals (Sweden)

    Manuel REQUENA

    2016-05-01

    Full Text Available Este artículo estudia los diversos procesos electorales de carácter municipal durante la II República en la provincia de Albacete, las constantes interferencias del Gobierno de turno sustituyendo los consistorios democráticamente elegidos por gubernamentales, la lucha por el control del poder local y las medidas adoptadas para resolver los problemas locales y la conflictividad generada.

  3. The Composite 259-kb Plasmid of Martelella mediterranea DSM 17316(T)-A Natural Replicon with Functional RepABC Modules from Rhodobacteraceae and Rhizobiaceae.

    Science.gov (United States)

    Bartling, Pascal; Brinkmann, Henner; Bunk, Boyke; Overmann, Jörg; Göker, Markus; Petersen, Jörn

    2017-01-01

    A multipartite genome organization with a chromosome and many extrachromosomal replicons (ECRs) is characteristic for Alphaproteobacteria. The best investigated ECRs of terrestrial rhizobia are the symbiotic plasmids for legume root nodulation and the tumor-inducing (Ti) plasmid of Agrobacterium tumefaciens. RepABC plasmids represent the most abundant alphaproteobacterial replicon type. The currently known homologous replication modules of rhizobia and Rhodobacteraceae are phylogenetically distinct. In this study, we surveyed type-strain genomes from the One Thousand Microbial Genomes (KMG-I) project and identified a roseobacter-specific RepABC-type operon in the draft genome of the marine rhizobium Martelella mediterranea DSM 17316(T). PacBio genome sequencing demonstrated the presence of three circular ECRs with sizes of 593, 259, and 170-kb. The rhodobacteral RepABC module is located together with a rhizobial equivalent on the intermediate sized plasmid pMM259, which likely originated in the fusion of a pre-existing rhizobial ECR with a conjugated roseobacter plasmid. Further evidence for horizontal gene transfer (HGT) is given by the presence of a roseobacter-specific type IV secretion system on the 259-kb plasmid and the rhodobacteracean origin of 62% of the genes on this plasmid. Functionality tests documented that the genuine rhizobial RepABC module from the Martelella 259-kb plasmid is only maintained in A. tumefaciens C58 (Rhizobiaceae) but not in Phaeobacter inhibens DSM 17395 (Rhodobacteraceae). Unexpectedly, the roseobacter-like replication system is functional and stably maintained in both host strains, thus providing evidence for a broader host range than previously proposed. In conclusion, pMM259 is the first example of a natural plasmid that likely mediates genetic exchange between roseobacters and rhizobia.

  4. The Composite 259-kb Plasmid of Martelella mediterranea DSM 17316T–A Natural Replicon with Functional RepABC Modules from Rhodobacteraceae and Rhizobiaceae

    Science.gov (United States)

    Bartling, Pascal; Brinkmann, Henner; Bunk, Boyke; Overmann, Jörg; Göker, Markus; Petersen, Jörn

    2017-01-01

    A multipartite genome organization with a chromosome and many extrachromosomal replicons (ECRs) is characteristic for Alphaproteobacteria. The best investigated ECRs of terrestrial rhizobia are the symbiotic plasmids for legume root nodulation and the tumor-inducing (Ti) plasmid of Agrobacterium tumefaciens. RepABC plasmids represent the most abundant alphaproteobacterial replicon type. The currently known homologous replication modules of rhizobia and Rhodobacteraceae are phylogenetically distinct. In this study, we surveyed type-strain genomes from the One Thousand Microbial Genomes (KMG-I) project and identified a roseobacter-specific RepABC-type operon in the draft genome of the marine rhizobium Martelella mediterranea DSM 17316T. PacBio genome sequencing demonstrated the presence of three circular ECRs with sizes of 593, 259, and 170-kb. The rhodobacteral RepABC module is located together with a rhizobial equivalent on the intermediate sized plasmid pMM259, which likely originated in the fusion of a pre-existing rhizobial ECR with a conjugated roseobacter plasmid. Further evidence for horizontal gene transfer (HGT) is given by the presence of a roseobacter-specific type IV secretion system on the 259-kb plasmid and the rhodobacteracean origin of 62% of the genes on this plasmid. Functionality tests documented that the genuine rhizobial RepABC module from the Martelella 259-kb plasmid is only maintained in A. tumefaciens C58 (Rhizobiaceae) but not in Phaeobacter inhibens DSM 17395 (Rhodobacteraceae). Unexpectedly, the roseobacter-like replication system is functional and stably maintained in both host strains, thus providing evidence for a broader host range than previously proposed. In conclusion, pMM259 is the first example of a natural plasmid that likely mediates genetic exchange between roseobacters and rhizobia. PMID:28983283

  5. Guidelines for Statistical Testing

    OpenAIRE

    Strigini, L.; Littlewood, B.; European Space Agency

    1997-01-01

    This document provides an introduction to statistical testing. Statistical testing of software is here defined as testing in which the test cases are produced by a random process meant to produce different test cases with the same probabilities with which they would arise in actual use of the software. Statistical testing of software has these main advantages: for the purpose of reliability assessment and product acceptance, it supports directly estimates of reliability, and thus decisions on...

  6. Applied statistics for economists

    CERN Document Server

    Lewis, Margaret

    2012-01-01

    This book is an undergraduate text that introduces students to commonly-used statistical methods in economics. Using examples based on contemporary economic issues and readily-available data, it not only explains the mechanics of the various methods, it also guides students to connect statistical results to detailed economic interpretations. Because the goal is for students to be able to apply the statistical methods presented, online sources for economic data and directions for performing each task in Excel are also included.

  7. Equilibrium statistical mechanics

    CERN Document Server

    Mayer, J E

    1968-01-01

    The International Encyclopedia of Physical Chemistry and Chemical Physics, Volume 1: Equilibrium Statistical Mechanics covers the fundamental principles and the development of theoretical aspects of equilibrium statistical mechanics. Statistical mechanical is the study of the connection between the macroscopic behavior of bulk matter and the microscopic properties of its constituent atoms and molecules. This book contains eight chapters, and begins with a presentation of the master equation used for the calculation of the fundamental thermodynamic functions. The succeeding chapters highlight t

  8. Mathematical statistics with applications

    CERN Document Server

    Wackerly, Dennis D; Scheaffer, Richard L

    2008-01-01

    In their bestselling MATHEMATICAL STATISTICS WITH APPLICATIONS, premiere authors Dennis Wackerly, William Mendenhall, and Richard L. Scheaffer present a solid foundation in statistical theory while conveying the relevance and importance of the theory in solving practical problems in the real world. The authors' use of practical applications and excellent exercises helps you discover the nature of statistics and understand its essential role in scientific research.

  9. Contributions to statistics

    CERN Document Server

    Mahalanobis, P C

    1965-01-01

    Contributions to Statistics focuses on the processes, methodologies, and approaches involved in statistics. The book is presented to Professor P. C. Mahalanobis on the occasion of his 70th birthday. The selection first offers information on the recovery of ancillary information and combinatorial properties of partially balanced designs and association schemes. Discussions focus on combinatorial applications of the algebra of association matrices, sample size analogy, association matrices and the algebra of association schemes, and conceptual statistical experiments. The book then examines latt

  10. Optimization techniques in statistics

    CERN Document Server

    Rustagi, Jagdish S

    1994-01-01

    Statistics help guide us to optimal decisions under uncertainty. A large variety of statistical problems are essentially solutions to optimization problems. The mathematical techniques of optimization are fundamentalto statistical theory and practice. In this book, Jagdish Rustagi provides full-spectrum coverage of these methods, ranging from classical optimization and Lagrange multipliers, to numerical techniques using gradients or direct search, to linear, nonlinear, and dynamic programming using the Kuhn-Tucker conditions or the Pontryagin maximal principle. Variational methods and optimiza

  11. Equilibrium statistical mechanics

    CERN Document Server

    Jackson, E Atlee

    2000-01-01

    Ideal as an elementary introduction to equilibrium statistical mechanics, this volume covers both classical and quantum methodology for open and closed systems. Introductory chapters familiarize readers with probability and microscopic models of systems, while additional chapters describe the general derivation of the fundamental statistical mechanics relationships. The final chapter contains 16 sections, each dealing with a different application, ordered according to complexity, from classical through degenerate quantum statistical mechanics. Key features include an elementary introduction t

  12. Lectures on statistical mechanics

    CERN Document Server

    Bowler, M G

    1982-01-01

    Anyone dissatisfied with the almost ritual dullness of many 'standard' texts in statistical mechanics will be grateful for the lucid explanation and generally reassuring tone. Aimed at securing firm foundations for equilibrium statistical mechanics, topics of great subtlety are presented transparently and enthusiastically. Very little mathematical preparation is required beyond elementary calculus and prerequisites in physics are limited to some elementary classical thermodynamics. Suitable as a basis for a first course in statistical mechanics, the book is an ideal supplement to more convent

  13. METAROUTE - Gestion de la qualité des données du repérage spatial et de la géométrie des axes routiers

    OpenAIRE

    Gilliéron, PY; Moreni, C.; Gilgen, M.; Konnen, J.

    2006-01-01

    Le système d’information de la route, anciennement appelé banque de données routières, repose principalement sur un système de repérage linéaire : le système de repérage spatial de base (SRB). Alors que la plupart des systèmes d’information géographique (SIG) reposent sur un système de repérage planaire, basé sur des coordonnées nationales, il est indispensable de faire cohabiter ces deux vues de l’espace. Les projets SYRROU et AGRAM ont montré la complémentarité des deux systèmes de repérage...

  14. Digest of education statistics

    National Research Council Canada - National Science Library

    Contains information on a variety of subjects within the field of education statistics, including the number of schools and colleges, enrollments, teachers, graduates, educational attainment, finances...

  15. Annual Statistical Supplement, 2002

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2002 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  16. Annual Statistical Supplement, 2003

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2003 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  17. Annual Statistical Supplement, 2001

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2001 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  18. Annual Statistical Supplement, 2010

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2010 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  19. Annual Statistical Supplement, 2007

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2007 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  20. Annual Statistical Supplement, 2016

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2016 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  1. Annual Statistical Supplement, 2000

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2000 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  2. Statistics in a Nutshell

    CERN Document Server

    Boslaugh, Sarah

    2008-01-01

    Need to learn statistics as part of your job, or want some help passing a statistics course? Statistics in a Nutshell is a clear and concise introduction and reference that's perfect for anyone with no previous background in the subject. This book gives you a solid understanding of statistics without being too simple, yet without the numbing complexity of most college texts. You get a firm grasp of the fundamentals and a hands-on understanding of how to apply them before moving on to the more advanced material that follows. Each chapter presents you with easy-to-follow descriptions illustrat

  3. Annual Statistical Supplement, 2008

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2008 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  4. Annual Statistical Supplement, 2006

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2006 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  5. Annual Statistical Supplement, 2005

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2005 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  6. Annual Statistical Supplement, 2015

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2015 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  7. Statistics is Easy

    CERN Document Server

    Shasha, Dennis

    2010-01-01

    Statistics is the activity of inferring results about a population given a sample. Historically, statistics books assume an underlying distribution to the data (typically, the normal distribution) and derive results under that assumption. Unfortunately, in real life, one cannot normally be sure of the underlying distribution. For that reason, this book presents a distribution-independent approach to statistics based on a simple computational counting idea called resampling. This book explains the basic concepts of resampling, then systematically presents the standard statistical measures along

  8. Annual Statistical Supplement, 2004

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2004 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  9. 100 statistical tests

    CERN Document Server

    Kanji, Gopal K

    2006-01-01

    This expanded and updated Third Edition of Gopal K. Kanji's best-selling resource on statistical tests covers all the most commonly used tests with information on how to calculate and interpret results with simple datasets. Each entry begins with a short summary statement about the test's purpose, and contains details of the test objective, the limitations (or assumptions) involved, a brief outline of the method, a worked example, and the numerical calculation. 100 Statistical Tests, Third Edition is the one indispensable guide for users of statistical materials and consumers of statistical information at all levels and across all disciplines.

  10. Understanding Computational Bayesian Statistics

    CERN Document Server

    Bolstad, William M

    2011-01-01

    A hands-on introduction to computational statistics from a Bayesian point of view Providing a solid grounding in statistics while uniquely covering the topics from a Bayesian perspective, Understanding Computational Bayesian Statistics successfully guides readers through this new, cutting-edge approach. With its hands-on treatment of the topic, the book shows how samples can be drawn from the posterior distribution when the formula giving its shape is all that is known, and how Bayesian inferences can be based on these samples from the posterior. These ideas are illustrated on common statistic

  11. Record Statistics and Dynamics

    DEFF Research Database (Denmark)

    Sibani, Paolo; Jensen, Henrik J.

    2009-01-01

    The term record statistics covers the statistical properties of records within an ordered series of numerical data obtained from observations or measurements. A record within such series is simply a value larger (or smaller) than all preceding values. The mathematical properties of records strongly...... fluctuations of e. g. the energy are able to push the system past some sort of ‘edge of stability’, inducing irreversible configurational changes, whose statistics then closely follows the statistics of record fluctuations....

  12. Principles of statistics

    CERN Document Server

    Bulmer, M G

    1979-01-01

    There are many textbooks which describe current methods of statistical analysis, while neglecting related theory. There are equally many advanced textbooks which delve into the far reaches of statistical theory, while bypassing practical applications. But between these two approaches is an unfilled gap, in which theory and practice merge at an intermediate level. Professor M. G. Bulmer's Principles of Statistics, originally published in 1965, was created to fill that need. The new, corrected Dover edition of Principles of Statistics makes this invaluable mid-level text available once again fo

  13. Annual Statistical Supplement, 2014

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2014 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  14. Annual Statistical Supplement, 2009

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2009 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  15. Annual Statistical Supplement, 2011

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2011 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  16. The protective immune response against Pseudorabies virus induced by DNA vaccination is impaired if the plasmid harbors a functional Porcine circovirus type 2 rep and origin of replication.

    Science.gov (United States)

    Faurez, Florence; Grasland, Béatrice; Béven, Véronique; Cariolet, Roland; Keranflec'h, André; Henry, Aurélie; Jestin, André; Dory, Daniel

    2012-12-01

    A plasmid rendered replicative in mammalian cells by inserting the Porcine circovirus 2 (PCV2) origin of replication and replicase gene (Ori-rep) has been previously constructed. The aim of the present study was to evaluate if the replication capacity of this plasmid could be advantageously used to improve the protective immunity induced by DNA vaccination. In this case we used the porcine Pseudorabies virus (PrV) DNA vaccination model. The replicative capacity of the DNA vaccine did not improve the protective immunity against PrV in pigs, but on the contrary the presence of the PCV2 Ori-rep sequence was harmful in the induction of this immunity compared to an equivalent but non-replicative DNA vaccine. In addition, the distribution and the persistence of the replicative and non-replicative plasmids inside the body were the same. This is the first study showing an in vivo deleterious effect of the replicative active PCV2 Ori-rep on the natural and specific protection against PrV infection. Copyright © 2012 Elsevier B.V. All rights reserved.

  17. Practical statistics for educators

    CERN Document Server

    Ravid, Ruth

    2014-01-01

    Practical Statistics for Educators, Fifth Edition, is a clear and easy-to-follow text written specifically for education students in introductory statistics courses and in action research courses. It is also a valuable resource and guidebook for educational practitioners who wish to study their own settings.

  18. Fermi–Dirac Statistics

    Indian Academy of Sciences (India)

    IAS Admin

    Dirac statistics, identical and in- distinguishable particles, Fermi gas. Fermi–Dirac Statistics. Derivation and Consequences. S Chaturvedi and Shyamal Biswas ... GENERAL. ARTICLE. RESONANCE. January 2014. 57. Historically, one of the first applications of. Fermi–Dirac distribution came from Fowler in the context of.

  19. Practical statistics simply explained

    CERN Document Server

    Langley, Dr Russell A

    1971-01-01

    For those who need to know statistics but shy away from math, this book teaches how to extract truth and draw valid conclusions from numerical data using logic and the philosophy of statistics rather than complex formulae. Lucid discussion of averages and scatter, investigation design, more. Problems with solutions.

  20. Thiele. Pioneer in statistics

    DEFF Research Database (Denmark)

    Lauritzen, Steffen Lilholt

    This book studies the brilliant Danish 19th Century astronomer, T.N. Thiele who made important contributions to statistics, actuarial science, astronomy and mathematics. The most important of these contributions in statistics are translated into English for the first time, and the text includes c...

  1. Statistical methods in metabolomics.

    Science.gov (United States)

    Korman, Alexander; Oh, Amy; Raskind, Alexander; Banks, David

    2012-01-01

    Metabolomics is the relatively new field in bioinformatics that uses measurements on metabolite abundance as a tool for disease diagnosis and other medical purposes. Although closely related to proteomics, the statistical analysis is potentially simpler since biochemists have significantly more domain knowledge about metabolites. This chapter reviews the challenges that metabolomics poses in the areas of quality control, statistical metrology, and data mining.

  2. On Statistical Testing.

    Science.gov (United States)

    Huberty, Carl J.

    An approach to statistical testing, which combines Neyman-Pearson hypothesis testing and Fisher significance testing, is recommended. The use of P-values in this approach is discussed in some detail. The author also discusses some problems which are often found in introductory statistics textbooks. The problems involve the definitions of…

  3. Applied Statistics with SPSS

    Science.gov (United States)

    Huizingh, Eelko K. R. E.

    2007-01-01

    Accessibly written and easy to use, "Applied Statistics Using SPSS" is an all-in-one self-study guide to SPSS and do-it-yourself guide to statistics. What is unique about Eelko Huizingh's approach is that this book is based around the needs of undergraduate students embarking on their own research project, and its self-help style is designed to…

  4. Handbook of Spatial Statistics

    CERN Document Server

    Gelfand, Alan E

    2010-01-01

    Offers an introduction detailing the evolution of the field of spatial statistics. This title focuses on the three main branches of spatial statistics: continuous spatial variation (point referenced data); discrete spatial variation, including lattice and areal unit data; and, spatial point patterns.

  5. Thiele. Pioneer in statistics

    DEFF Research Database (Denmark)

    Lauritzen, Steffen Lilholt

    This book studies the brilliant Danish 19th Century astronomer, T.N. Thiele who made important contributions to statistics, actuarial science, astronomy and mathematics. The most important of these contributions in statistics are translated into English for the first time, and the text includes...

  6. Enhancing statistical literacy

    NARCIS (Netherlands)

    Droogers, M.J.S.|info:eu-repo/dai/nl/413392252; Drijvers, P.H.M.|info:eu-repo/dai/nl/074302922

    2017-01-01

    Current secondary school statistics curricula focus on procedural knowledge and pay too little attention to statistical reasoning. As a result, students are not able to apply their knowledge to practice. In addition, education often targets the average student, which may lead to gifted students

  7. Fisher's Contributions to Statistics

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 9. Fisher's Contributions to Statistics. T Krishnan. General Article Volume 2 Issue 9 September 1997 pp 32-37 ... Author Affiliations. T Krishnan1. Computer Science Unit, Indian Statistical Institute, 203 B T Road, Calcutta 700 035, India ...

  8. Reform in Statistical Education

    Science.gov (United States)

    Huck, Schuyler W.

    2007-01-01

    Two questions are considered in this article: (a) What should professionals in school psychology do in an effort to stay current with developments in applied statistics? (b) What should they do with their existing knowledge to move from surface understanding of statistics to deep understanding? Written for school psychologists who have completed…

  9. Comparison of semi-automated commercial rep-PCR fingerprinting, spoligotyping, 12-locus MIRU-VNTR typing and single nucleotide polymorphism analysis of the embB gene as molecular typing tools for Mycobacterium bovis.

    Science.gov (United States)

    Armas, Federica; Camperio, Cristina; Coltella, Luana; Selvaggini, Serena; Boniotti, Maria Beatrice; Pacciarini, Maria Lodovica; Di Marco Lo Presti, Vincenzo; Marianelli, Cinzia

    2017-08-04

    Highly discriminatory genotyping strategies are essential in molecular epidemiological studies of tuberculosis. In this study we evaluated, for the first time, the efficacy of the repetitive sequence-based PCR (rep-PCR) DiversiLab Mycobacterium typing kit over spoligotyping, 12-locus mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing and embB single nucleotide polymorphism (SNP) analysis for Mycobacterium bovis typing. A total of 49 M. bovis animal isolates were used. DNA was extracted and genomic DNA was amplified using the DiversiLab Mycobacterium typing kit. The amplified fragments were separated and detected using a microfluidics chip with Agilent 2100. The resulting rep-PCR-based DNA fingerprints were uploaded to and analysed using web-based DiversiLab software through Pearson's correlation coefficient. Rep-PCR DiversiLab grouped M. bovis isolates into ten different clusters. Most isolates sharing identical spoligotype, MIRU-VNTR profile or embB gene polymorphism were grouped into different rep-PCR clusters. Rep-PCR DiversiLab displayed greater discriminatory power than spoligotyping and embB SNP analysis but a lower resolution power than the 12-locus MIRU-VNTR analysis. MIRU-VNTR confirmed that it is superior to the other PCR-based methods tested here. In combination with spoligotyping and 12-locus MIRU-VNTR analysis, rep-PCR improved the discriminatory power for M. bovis typing.

  10. Understanding advanced statistical methods

    CERN Document Server

    Westfall, Peter

    2013-01-01

    Introduction: Probability, Statistics, and ScienceReality, Nature, Science, and ModelsStatistical Processes: Nature, Design and Measurement, and DataModelsDeterministic ModelsVariabilityParametersPurely Probabilistic Statistical ModelsStatistical Models with Both Deterministic and Probabilistic ComponentsStatistical InferenceGood and Bad ModelsUses of Probability ModelsRandom Variables and Their Probability DistributionsIntroductionTypes of Random Variables: Nominal, Ordinal, and ContinuousDiscrete Probability Distribution FunctionsContinuous Probability Distribution FunctionsSome Calculus-Derivatives and Least SquaresMore Calculus-Integrals and Cumulative Distribution FunctionsProbability Calculation and SimulationIntroductionAnalytic Calculations, Discrete and Continuous CasesSimulation-Based ApproximationGenerating Random NumbersIdentifying DistributionsIntroductionIdentifying Distributions from Theory AloneUsing Data: Estimating Distributions via the HistogramQuantiles: Theoretical and Data-Based Estimate...

  11. Introduction to Bayesian statistics

    CERN Document Server

    Bolstad, William M

    2017-01-01

    There is a strong upsurge in the use of Bayesian methods in applied statistical analysis, yet most introductory statistics texts only present frequentist methods. Bayesian statistics has many important advantages that students should learn about if they are going into fields where statistics will be used. In this Third Edition, four newly-added chapters address topics that reflect the rapid advances in the field of Bayesian staistics. The author continues to provide a Bayesian treatment of introductory statistical topics, such as scientific data gathering, discrete random variables, robust Bayesian methods, and Bayesian approaches to inferenfe cfor discrete random variables, bionomial proprotion, Poisson, normal mean, and simple linear regression. In addition, newly-developing topics in the field are presented in four new chapters: Bayesian inference with unknown mean and variance; Bayesian inference for Multivariate Normal mean vector; Bayesian inference for Multiple Linear RegressionModel; and Computati...

  12. Morfometría fluvial aplicada a una cuenca urbana en Ingeniero White, República Argentina

    Directory of Open Access Journals (Sweden)

    Alicia María Campo

    2012-04-01

    Full Text Available La morfometría fluvial estudia diversas variables que caracterizan la forma de una cuenca de drenaje. El objetivo de este trabajo es aplicar el método morfométrico de cuencas naturales a una cuenca urbana. El área en estudio (6 km2 drena sus aguas al frente costero y comprende la localidad de Ingeniero White, República Argentina. Se realizó la jerarquización de la red de drenaje. Se identificaron tres subcuencas con escasa pendiente que presentan eventos de inundación, con mayor peligrosidad con precipitaciones extremas. Los valores de relación de longitud indicaron mayor concentración de energía en eventos de grandes avenidas. Los valores de relación de elongación demostraron que una de las subcuencas es de forma circular y presenta mayor velocidad en las avenidas de la escorrentía. Las dos cuencas más elongadas tienen mayor retardo en las avenidas. El mayor caudal del área en estudio fluye por la cuenca que posee el mayor número de orden y la mayor superficie. Las otras dos cuencas están sujetas a crecientes instantáneas y de respuesta inmediata. Los valores de pendiente y de área aplicados a modelos hidrológicos e hidraúlico determinaron la sección de los conductos y canales. El caudal calculado para el área drenada fue de 22.41 m3/s.

  13. Transformaciones y cambios en la policía española durante la Segunda República

    Directory of Open Access Journals (Sweden)

    José María Miguélez Rueda

    1997-01-01

    Full Text Available El viejo aparato de Policía que heredó la II República se componía de dos colectivos desiguales: el militar Cuerpo de Seguridad, que dependía de los Ministerios de la Gobernación y de la Guerra, era un cuerpo dedicado a prevenir y reprimir las alteraciones del orden público, en cuya labor había causado y sufrido muchas bajas; por su parte, el menos numeroso y civil Cuerpo de Vigilancia, cuyos miembros actuaban de paisano, debía investigar los delitos y perseguir a los delincuentes, y se había distinguido en el reciente pasado por su ejecutoria contra los antimonárquicos. Tras la victoriosa proclamación del 14 de abril de 1931, gobernantes y policías se observaron con mutua desconfianza y un cierto temor.The old Police machine that the II Republic inherited was composed by two unequal collectives: the military "Cuerpo de Seguridad» which depended of the Government Office and War Office, it was an Institute dedicated to prevent and to repress the public order disorders in which work it had produced and suffered a lot of dead and injured; on the order hand the less numerous and civil «Cuerpo de Vigilancia», whose members worked in plain clothes, had to investigate the crimes and to pursue the crimináis, and it had been distinguished its activity against the antimonarchicals in the recent past. After the victorious proclamation of 14th april 1931, the governing persons and the policemen regarded each other wlth diffidence and a certain fear.

  14. La creación de la lengua común (putonghua en la república popular China

    Directory of Open Access Journals (Sweden)

    José Cuadrado Moreno

    2011-04-01

    Full Text Available Normal 0 21 false false false ES X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} En este trabajo se describen la evolución de la política y la planificación lingüísticas relacionadas con la lengua hablada normativa en China continental. Se analizan la situación mullilingüíslica actual de la República Popular (§ 1, la política y la planificación lingüísticas del chino hablado (§2, la planificación de su  importancia (§3, y la planificación de su adquisición (§4.

  15. Categorización del estado de conservación de las tortugas de la República Argentina

    Directory of Open Access Journals (Sweden)

    Prosdocimi, Laura

    2012-11-01

    Full Text Available Con la participación de nueve especialistas de diferentes instituciones de Argentina y transcurridos más de 10 años desde la primera Lista Roja de la herpetofauna de la República Argentina realizada por la Asociación Herpetológica Argentina en el año 2000, se re-categorizaron los taxones de Testudines presentes en el país incorporando nueva información taxonómica, biológica y ecológica y, aplicando correcciones metodológicas. Como resultado, de los 14 taxones de tortugas continentales y marinas, nueve quedaron incluidas en la presente Lista Roja bajo algún grado de amenaza, tres En Peligro, tres Amenazadas y tres Vulnerables, mientras que dos fueron categorizadas como No Amenazadas y tres son Insuficientemente Conocidas. En la evaluación de las tres especies de tortugas marinas, que frecuentan las costas del Mar Argentino, se homologaron las categorías con las de IUCN (2011. Respecto de la categorización anterior, se agregó la especie Phrynops geoffranus (Insuficientemente Conocida, se sinonimizaron dos especies, disminuyó el número de especies En Peligro de tres a dos y se incrementó el de Vulnerables de una a tres. Los pocos cambios resultantes de la presente categorización de las tortugas de Argentina respecto de la anterior podría reflejar la escasez de estudios realizados sobre este grupo en la última década y la necesidad de promoverlos.

  16. Statistical physics; Physique statistique

    Energy Technology Data Exchange (ETDEWEB)

    Couture, L.; Zitoun, R. [Universite Pierre et Marie Curie, 75 - Paris (France)

    1992-12-31

    The basis of statistical physics is exposed. The statistical models of Maxwell-Boltzmann, of Bose-Einstein and of Fermi-Dirac and their particular application fields are presented. The statistical theory is applied in different ranges of physics: gas characteristics, paramagnetism, crystal thermal properties and solid electronic properties. A whole chapter is dedicated to helium and its characteristics such as superfluidity, another deals with superconductivity. Superconductivity is presented both experimentally and theoretically. Meissner effect and Josephson effect are described and the framework of BCS theory is drawn. (A.C.)

  17. Statistical Pattern Recognition

    CERN Document Server

    Webb, Andrew R

    2011-01-01

    Statistical pattern recognition relates to the use of statistical techniques for analysing data measurements in order to extract information and make justified decisions.  It is a very active area of study and research, which has seen many advances in recent years. Applications such as data mining, web searching, multimedia data retrieval, face recognition, and cursive handwriting recognition, all require robust and efficient pattern recognition techniques. This third edition provides an introduction to statistical pattern theory and techniques, with material drawn from a wide range of fields,

  18. Statistics a complete introduction

    CERN Document Server

    Graham, Alan

    2013-01-01

    Statistics: A Complete Introduction is the most comprehensive yet easy-to-use introduction to using Statistics. Written by a leading expert, this book will help you if you are studying for an important exam or essay, or if you simply want to improve your knowledge. The book covers all the key areas of Statistics including graphs, data interpretation, spreadsheets, regression, correlation and probability. Everything you will need is here in this one book. Each chapter includes not only an explanation of the knowledge and skills you need, but also worked examples and test questions.

  19. Statistical deception at work

    CERN Document Server

    Mauro, John

    2013-01-01

    Written to reveal statistical deceptions often thrust upon unsuspecting journalists, this book views the use of numbers from a public perspective. Illustrating how the statistical naivete of journalists often nourishes quantitative misinformation, the author's intent is to make journalists more critical appraisers of numerical data so that in reporting them they do not deceive the public. The book frequently uses actual reported examples of misused statistical data reported by mass media and describes how journalists can avoid being taken in by them. Because reports of survey findings seldom g

  20. Evolutionary Statistical Procedures

    CERN Document Server

    Baragona, Roberto; Poli, Irene

    2011-01-01

    This proposed text appears to be a good introduction to evolutionary computation for use in applied statistics research. The authors draw from a vast base of knowledge about the current literature in both the design of evolutionary algorithms and statistical techniques. Modern statistical research is on the threshold of solving increasingly complex problems in high dimensions, and the generalization of its methodology to parameters whose estimators do not follow mathematically simple distributions is underway. Many of these challenges involve optimizing functions for which analytic solutions a

  1. The nature of statistics

    CERN Document Server

    Wallis, W Allen

    2014-01-01

    Focusing on everyday applications as well as those of scientific research, this classic of modern statistical methods requires little to no mathematical background. Readers develop basic skills for evaluating and using statistical data. Lively, relevant examples include applications to business, government, social and physical sciences, genetics, medicine, and public health. ""W. Allen Wallis and Harry V. Roberts have made statistics fascinating."" - The New York Times ""The authors have set out with considerable success, to write a text which would be of interest and value to the student who,

  2. Statistical Group Comparison

    CERN Document Server

    Liao, Tim Futing

    2011-01-01

    An incomparably useful examination of statistical methods for comparisonThe nature of doing science, be it natural or social, inevitably calls for comparison. Statistical methods are at the heart of such comparison, for they not only help us gain understanding of the world around us but often define how our research is to be carried out. The need to compare between groups is best exemplified by experiments, which have clearly defined statistical methods. However, true experiments are not always possible. What complicates the matter more is a great deal of diversity in factors that are not inde

  3. AP statistics crash course

    CERN Document Server

    D'Alessio, Michael

    2012-01-01

    AP Statistics Crash Course - Gets You a Higher Advanced Placement Score in Less Time Crash Course is perfect for the time-crunched student, the last-minute studier, or anyone who wants a refresher on the subject. AP Statistics Crash Course gives you: Targeted, Focused Review - Study Only What You Need to Know Crash Course is based on an in-depth analysis of the AP Statistics course description outline and actual Advanced Placement test questions. It covers only the information tested on the exam, so you can make the most of your valuable study time. Our easy-to-read format covers: exploring da

  4. The World of Statistics

    Directory of Open Access Journals (Sweden)

    NIS

    2014-06-01

    Full Text Available The International Workshop New Challenges for Statistical Software – The Use of R in Official Statistics was the second of a series of events dedicated to the use of R Project in Romania and initiated by R-omanian R team. We are pleased to announce that 4th of April is the anniversary or R-omanian R team as an R User Group. One year ago, on 4th of April, was taking place the 1st workshop dedicated to the use of R – Workshop State-of-the-art statistical software commonly used in applied economics.

  5. Informal Statistics Help Desk

    Science.gov (United States)

    Young, M.; Koslovsky, M.; Schaefer, Caroline M.; Feiveson, A. H.

    2017-01-01

    Back by popular demand, the JSC Biostatistics Laboratory and LSAH statisticians are offering an opportunity to discuss your statistical challenges and needs. Take the opportunity to meet the individuals offering expert statistical support to the JSC community. Join us for an informal conversation about any questions you may have encountered with issues of experimental design, analysis, or data visualization. Get answers to common questions about sample size, repeated measures, statistical assumptions, missing data, multiple testing, time-to-event data, and when to trust the results of your analyses.

  6. Cancer Data and Statistics Tools

    Science.gov (United States)

    ... National Cancer Conference Stay Informed Cancer Data and Statistics Tools Recommend on Facebook Tweet Share Compartir United States Cancer Statistics The United States Cancer Statistics (USCS): Incidence and ...

  7. Plague Maps and Statistics

    Science.gov (United States)

    ... and Statistics Recommend on Facebook Tweet Share Compartir Plague in the United States Plague was first introduced ... per year in the United States: 1900-2012. Plague Worldwide Plague epidemics have occurred in Africa, Asia, ...

  8. CDC WONDER: Cancer Statistics

    Data.gov (United States)

    U.S. Department of Health & Human Services — The United States Cancer Statistics (USCS) online databases in WONDER provide cancer incidence and mortality data for the United States for the years since 1999, by...

  9. Information theory and statistics

    CERN Document Server

    Kullback, Solomon

    1968-01-01

    Highly useful text studies logarithmic measures of information and their application to testing statistical hypotheses. Includes numerous worked examples and problems. References. Glossary. Appendix. 1968 2nd, revised edition.

  10. Blood Facts and Statistics

    Science.gov (United States)

    ... Donor Community Learn About Blood Blood Facts and Statistics Blood Types Blood Components What Happens to Donated Blood Blood and Diversity History of Blood Transfusion Iron and Blood Donation Hosting ...

  11. Statistics for Finance

    DEFF Research Database (Denmark)

    Lindström, Erik; Madsen, Henrik; Nielsen, Jan Nygaard

    Statistics for Finance develops students’ professional skills in statistics with applications in finance. Developed from the authors’ courses at the Technical University of Denmark and Lund University, the text bridges the gap between classical, rigorous treatments of financial mathematics...... that rarely connect concepts to data and books on econometrics and time series analysis that do not cover specific problems related to option valuation. The book discusses applications of financial derivatives pertaining to risk assessment and elimination. The authors cover various statistical......, identify interest rate models, value bonds, estimate parameters, and much more. This textbook will help students understand and manage empirical research in financial engineering. It includes examples of how the statistical tools can be used to improve value-at-risk calculations and other issues...

  12. Statistical mechanics of superconductivity

    CERN Document Server

    Kita, Takafumi

    2015-01-01

    This book provides a theoretical, step-by-step comprehensive explanation of superconductivity for undergraduate and graduate students who have completed elementary courses on thermodynamics and quantum mechanics. To this end, it adopts the unique approach of starting with the statistical mechanics of quantum ideal gases and successively adding and clarifying elements and techniques indispensible for understanding it. They include the spin-statistics theorem, second quantization, density matrices, the Bloch–De Dominicis theorem, the variational principle in statistical mechanics, attractive interaction, and bound states. Ample examples of their usage are also provided in terms of topics from advanced statistical mechanics such as two-particle correlations of quantum ideal gases, derivation of the Hartree–Fock equations, and Landau’s Fermi-liquid theory, among others. With these preliminaries, the fundamental mean-field equations of superconductivity are derived with maximum mathematical clarity based on ...

  13. Illinois travel statistics, 2010

    Science.gov (United States)

    2011-01-01

    The 2010 Illinois Travel Statistics publication is assembled to provide detailed traffic : information to the different users of traffic data. While most users of traffic data at this level : of detail are within the Illinois Department of Transporta...

  14. Illinois travel statistics, 2008

    Science.gov (United States)

    2009-01-01

    The 2008 Illinois Travel Statistics publication is assembled to provide detailed traffic : information to the different users of traffic data. While most users of traffic data at this level : of detail are within the Illinois Department of Transporta...

  15. Illinois travel statistics, 2009

    Science.gov (United States)

    2010-01-01

    The 2009 Illinois Travel Statistics publication is assembled to provide detailed traffic : information to the different users of traffic data. While most users of traffic data at this level : of detail are within the Illinois Department of Transporta...

  16. Statistical Measures of Marksmanship

    National Research Council Canada - National Science Library

    Johnson, Richard

    2001-01-01

    .... This report describes objective statistical procedures to measure both rifle marksmanship accuracy, the proximity of an array of shots to the center of mass of a target, and marksmanship precision...

  17. Basics of statistical physics

    CERN Document Server

    Müller-Kirsten, Harald J W

    2013-01-01

    Statistics links microscopic and macroscopic phenomena, and requires for this reason a large number of microscopic elements like atoms. The results are values of maximum probability or of averaging. This introduction to statistical physics concentrates on the basic principles, and attempts to explain these in simple terms supplemented by numerous examples. These basic principles include the difference between classical and quantum statistics, a priori probabilities as related to degeneracies, the vital aspect of indistinguishability as compared with distinguishability in classical physics, the differences between conserved and non-conserved elements, the different ways of counting arrangements in the three statistics (Maxwell-Boltzmann, Fermi-Dirac, Bose-Einstein), the difference between maximization of the number of arrangements of elements, and averaging in the Darwin-Fowler method. Significant applications to solids, radiation and electrons in metals are treated in separate chapters, as well as Bose-Eins...

  18. Information theory and statistics

    CERN Document Server

    Kullback, Solomon

    1997-01-01

    Highly useful text studies logarithmic measures of information and their application to testing statistical hypotheses. Includes numerous worked examples and problems. References. Glossary. Appendix. 1968 2nd, revised edition.

  19. Mental Illness Statistics

    Science.gov (United States)

    ... Post-Traumatic Stress Disorder (PTSD) Schizophrenia Suicide All Statistics Topics: A-Z Agoraphobia Anorexia Nervosa Any Anxiety Disorder Any Mood Disorder Attention-Deficit/Hyperactivity Disorder (ADHD) Autism Spectrum ...

  20. Data and Statistics

    Science.gov (United States)

    ... Websites About Us Information For… Media Policy Makers Data & Statistics Recommend on Facebook Tweet Share Compartir Sickle ... Findings Feature Articles Key Findings: CDC’s Sickle Cell Data Collection Program Data Useful in Describing Patterns of ...

  1. Statistics for Finance

    DEFF Research Database (Denmark)

    Lindström, Erik; Madsen, Henrik; Nielsen, Jan Nygaard

    , identify interest rate models, value bonds, estimate parameters, and much more. This textbook will help students understand and manage empirical research in financial engineering. It includes examples of how the statistical tools can be used to improve value-at-risk calculations and other issues......Statistics for Finance develops students’ professional skills in statistics with applications in finance. Developed from the authors’ courses at the Technical University of Denmark and Lund University, the text bridges the gap between classical, rigorous treatments of financial mathematics...... that rarely connect concepts to data and books on econometrics and time series analysis that do not cover specific problems related to option valuation. The book discusses applications of financial derivatives pertaining to risk assessment and elimination. The authors cover various statistical...

  2. Transport statistics 1996

    CSIR Research Space (South Africa)

    Shepperson, L

    1997-12-01

    Full Text Available This publication contains transport and related statistics on roads, vehicles, infrastructure, passengers, freight, rail, air, maritime and road traffic, and international comparisons. The information compiled in this publication has been gathered...

  3. CMS Statistics Reference Booklet

    Data.gov (United States)

    U.S. Department of Health & Human Services — The annual CMS Statistics reference booklet provides a quick reference for summary information about health expenditures and the Medicare and Medicaid health...

  4. EDI Performance Statistics

    Data.gov (United States)

    U.S. Department of Health & Human Services — This section contains statistical information and reports related to the percentage of electronic transactions being sent to Medicare contractors in the formats...

  5. Statistical theory of heat

    CERN Document Server

    Scheck, Florian

    2016-01-01

    Scheck’s textbook starts with a concise introduction to classical thermodynamics, including geometrical aspects. Then a short introduction to probabilities and statistics lays the basis for the statistical interpretation of thermodynamics. Phase transitions, discrete models and the stability of matter are explained in great detail. Thermodynamics has a special role in theoretical physics. Due to the general approach of thermodynamics the field has a bridging function between several areas like the theory of condensed matter, elementary particle physics, astrophysics and cosmology. The classical thermodynamics describes predominantly averaged properties of matter, reaching from few particle systems and state of matter to stellar objects. Statistical Thermodynamics covers the same fields, but explores them in greater depth and unifies classical statistical mechanics with quantum theory of multiple particle systems. The content is presented as two tracks: the fast track for master students, providing the essen...

  6. Titanic: A Statistical Exploration.

    Science.gov (United States)

    Takis, Sandra L.

    1999-01-01

    Uses the available data about the Titanic's passengers to interest students in exploring categorical data and the chi-square distribution. Describes activities incorporated into a statistics class and gives additional resources for collecting information about the Titanic. (ASK)

  7. Heroin: Statistics and Trends

    Science.gov (United States)

    ... Science Adolescent Brain Comorbidity College-Age & Young Adults Criminal Justice Drugged Driving Drug Testing Drugs and the ... opioid overdose Statistics and Trends Swipe left or right to scroll. Monitoring the Future Study: Trends in ...

  8. Boating Accident Statistics

    Data.gov (United States)

    Department of Homeland Security — Accident statistics available on the Coast Guard’s website by state, year, and one variable to obtain tables and/or graphs. Data from reports has been loaded for...

  9. Elements of statistical thermodynamics

    CERN Document Server

    Nash, Leonard K

    2006-01-01

    Encompassing essentially all aspects of statistical mechanics that appear in undergraduate texts, this concise, elementary treatment shows how an atomic-molecular perspective yields new insights into macroscopic thermodynamics. 1974 edition.

  10. Statistics for Finance

    DEFF Research Database (Denmark)

    Lindström, Erik; Madsen, Henrik; Nielsen, Jan Nygaard

    that rarely connect concepts to data and books on econometrics and time series analysis that do not cover specific problems related to option valuation. The book discusses applications of financial derivatives pertaining to risk assessment and elimination. The authors cover various statistical......Statistics for Finance develops students’ professional skills in statistics with applications in finance. Developed from the authors’ courses at the Technical University of Denmark and Lund University, the text bridges the gap between classical, rigorous treatments of financial mathematics......, identify interest rate models, value bonds, estimate parameters, and much more. This textbook will help students understand and manage empirical research in financial engineering. It includes examples of how the statistical tools can be used to improve value-at-risk calculations and other issues...

  11. Business statistics I essentials

    CERN Document Server

    Clark, Louise

    2014-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Business Statistics I includes descriptive statistics, introduction to probability, probability distributions, sampling and sampling distributions, interval estimation, and hypothesis t

  12. Understanding descriptive statistics.

    Science.gov (United States)

    Fisher, Murray J; Marshall, Andrea P

    2009-05-01

    There is an increasing expectation that critical care nurses use clinical research when making decisions about patient care. This article is the second in a series which addresses statistics for clinical nursing practice. In this article we provide an introduction to the use of descriptive statistics. Concepts such as levels of measurement, measures of central tendency and dispersion are described and their use in clinical practice is illustrated.

  13. Statistic>

    DEFF Research Database (Denmark)

    Hansen, Flemming Tvede

    2008-01-01

    Co-organizer for and participant at the exhibition: Statistic>Statistic>2-16/3 2008 Museum fur Kunst und Gewerbe, Hamburg 3/4-27/4 2008...

  14. Statistical Engine Knock Control

    DEFF Research Database (Denmark)

    Stotsky, Alexander A.

    2008-01-01

    A new statistical concept of the knock control of a spark ignition automotive engine is proposed . The control aim is associated with the statistical hy pothesis test which compares the threshold value to the average value of the max imal amplitud e of the knock sensor signal at a given freq uency...... which includ es generation of the amplitud e signals, a threshold value d etermination and a knock sound mod el is d eveloped for evaluation of the control concept....

  15. Breakthroughs in statistics

    CERN Document Server

    Johnson, Norman

    This is author-approved bcc: This is the third volume of a collection of seminal papers in the statistical sciences written during the past 110 years. These papers have each had an outstanding influence on the development of statistical theory and practice over the last century. Each paper is preceded by an introduction written by an authority in the field providing background information and assessing its influence. Volume III concerntrates on articles from the 1980's while including some earlier articles not included in Volume I and II. Samuel Kotz is Professor of Statistics in the College of Business and Management at the University of Maryland. Norman L. Johnson is Professor Emeritus of Statistics at the University of North Carolina. Also available: Breakthroughs in Statistics Volume I: Foundations and Basic Theory Samuel Kotz and Norman L. Johnson, Editors 1993. 631 pp. Softcover. ISBN 0-387-94037-5 Breakthroughs in Statistics Volume II: Methodology and Distribution Samuel Kotz and Norman L. Johnson, Edi...

  16. UN Data: Environment Statistics: Waste

    Data.gov (United States)

    World Wide Human Geography Data Working Group — The Environment Statistics Database contains selected water and waste statistics by country. Statistics on water and waste are based on official statistics supplied...

  17. UN Data- Environmental Statistics: Waste

    Data.gov (United States)

    World Wide Human Geography Data Working Group — The Environment Statistics Database contains selected water and waste statistics by country. Statistics on water and waste are based on official statistics supplied...

  18. Multivariate Statistical Process Control

    DEFF Research Database (Denmark)

    Kulahci, Murat

    2013-01-01

    As sensor and computer technology continues to improve, it becomes a normal occurrence that we confront with high dimensional data sets. As in many areas of industrial statistics, this brings forth various challenges in statistical process control (SPC) and monitoring for which the aim is to iden......As sensor and computer technology continues to improve, it becomes a normal occurrence that we confront with high dimensional data sets. As in many areas of industrial statistics, this brings forth various challenges in statistical process control (SPC) and monitoring for which the aim...... is to identify “out-of-control” state of a process using control charts in order to reduce the excessive variation caused by so-called assignable causes. In practice, the most common method of monitoring multivariate data is through a statistic akin to the Hotelling’s T2. For high dimensional data with excessive...... amount of cross correlation, practitioners are often recommended to use latent structures methods such as Principal Component Analysis to summarize the data in only a few linear combinations of the original variables that capture most of the variation in the data. Applications of these control charts...

  19. Intuitive introductory statistics

    CERN Document Server

    Wolfe, Douglas A

    2017-01-01

    This textbook is designed to give an engaging introduction to statistics and the art of data analysis. The unique scope includes, but also goes beyond, classical methodology associated with the normal distribution. What if the normal model is not valid for a particular data set? This cutting-edge approach provides the alternatives. It is an introduction to the world and possibilities of statistics that uses exercises, computer analyses, and simulations throughout the core lessons. These elementary statistical methods are intuitive. Counting and ranking features prominently in the text. Nonparametric methods, for instance, are often based on counts and ranks and are very easy to integrate into an introductory course. The ease of computation with advanced calculators and statistical software, both of which factor into this text, allows important techniques to be introduced earlier in the study of statistics. This book's novel scope also includes measuring symmetry with Walsh averages, finding a nonp...

  20. Energy statistics manual

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Detailed, complete, timely and reliable statistics are essential to monitor the energy situation at a country level as well as at an international level. Energy statistics on supply, trade, stocks, transformation and demand are indeed the basis for any sound energy policy decision. For instance, the market of oil -- which is the largest traded commodity worldwide -- needs to be closely monitored in order for all market players to know at any time what is produced, traded, stocked and consumed and by whom. In view of the role and importance of energy in world development, one would expect that basic energy information to be readily available and reliable. This is not always the case and one can even observe a decline in the quality, coverage and timeliness of energy statistics over the last few years.

  1. Philosophy of statistics

    CERN Document Server

    Forster, Malcolm R

    2011-01-01

    Statisticians and philosophers of science have many common interests but restricted communication with each other. This volume aims to remedy these shortcomings. It provides state-of-the-art research in the area of philosophy of statistics by encouraging numerous experts to communicate with one another without feeling "restricted” by their disciplines or thinking "piecemeal” in their treatment of issues. A second goal of this book is to present work in the field without bias toward any particular statistical paradigm. Broadly speaking, the essays in this Handbook are concerned with problems of induction, statistics and probability. For centuries, foundational problems like induction have been among philosophers' favorite topics; recently, however, non-philosophers have increasingly taken a keen interest in these issues. This volume accordingly contains papers by both philosophers and non-philosophers, including scholars from nine academic disciplines.

  2. Probability and Bayesian statistics

    CERN Document Server

    1987-01-01

    This book contains selected and refereed contributions to the "Inter­ national Symposium on Probability and Bayesian Statistics" which was orga­ nized to celebrate the 80th birthday of Professor Bruno de Finetti at his birthplace Innsbruck in Austria. Since Professor de Finetti died in 1985 the symposium was dedicated to the memory of Bruno de Finetti and took place at Igls near Innsbruck from 23 to 26 September 1986. Some of the pa­ pers are published especially by the relationship to Bruno de Finetti's scientific work. The evolution of stochastics shows growing importance of probability as coherent assessment of numerical values as degrees of believe in certain events. This is the basis for Bayesian inference in the sense of modern statistics. The contributions in this volume cover a broad spectrum ranging from foundations of probability across psychological aspects of formulating sub­ jective probability statements, abstract measure theoretical considerations, contributions to theoretical statistics an...

  3. Statistics for Finance

    DEFF Research Database (Denmark)

    Lindström, Erik; Madsen, Henrik; Nielsen, Jan Nygaard

    Statistics for Finance develops students’ professional skills in statistics with applications in finance. Developed from the authors’ courses at the Technical University of Denmark and Lund University, the text bridges the gap between classical, rigorous treatments of financial mathematics...... that rarely connect concepts to data and books on econometrics and time series analysis that do not cover specific problems related to option valuation. The book discusses applications of financial derivatives pertaining to risk assessment and elimination. The authors cover various statistical...... and mathematical techniques, including linear and nonlinear time series analysis, stochastic calculus models, stochastic differential equations, Itō’s formula, the Black–Scholes model, the generalized method-of-moments, and the Kalman filter. They explain how these tools are used to price financial derivatives...

  4. Per Object statistical analysis

    DEFF Research Database (Denmark)

    2008-01-01

    This RS code is to do Object-by-Object analysis of each Object's sub-objects, e.g. statistical analysis of an object's individual image data pixels. Statistics, such as percentiles (so-called "quartiles") are derived by the process, but the return of that can only be a Scene Variable, not an Object...... an analysis of the values of the object's pixels in MS-Excel. The shell of the proceedure could also be used for purposes other than just the derivation of Object - Sub-object statistics, e.g. rule-based assigment processes....... Variable. This procedure was developed in order to be able to export objects as ESRI shape data with the 90-percentile of the Hue of each object's pixels as an item in the shape attribute table. This procedure uses a sub-level single pixel chessboard segmentation, loops for each of the objects...

  5. Perception in statistical graphics

    Science.gov (United States)

    VanderPlas, Susan Ruth

    There has been quite a bit of research on statistical graphics and visualization, generally focused on new types of graphics, new software to create graphics, interactivity, and usability studies. Our ability to interpret and use statistical graphics hinges on the interface between the graph itself and the brain that perceives and interprets it, and there is substantially less research on the interplay between graph, eye, brain, and mind than is sufficient to understand the nature of these relationships. The goal of the work presented here is to further explore the interplay between a static graph, the translation of that graph from paper to mental representation (the journey from eye to brain), and the mental processes that operate on that graph once it is transferred into memory (mind). Understanding the perception of statistical graphics should allow researchers to create more effective graphs which produce fewer distortions and viewer errors while reducing the cognitive load necessary to understand the information presented in the graph. Taken together, these experiments should lay a foundation for exploring the perception of statistical graphics. There has been considerable research into the accuracy of numerical judgments viewers make from graphs, and these studies are useful, but it is more effective to understand how errors in these judgments occur so that the root cause of the error can be addressed directly. Understanding how visual reasoning relates to the ability to make judgments from graphs allows us to tailor graphics to particular target audiences. In addition, understanding the hierarchy of salient features in statistical graphics allows us to clearly communicate the important message from data or statistical models by constructing graphics which are designed specifically for the perceptual system.

  6. "O dia de amanhã": a República nas páginas do periódico ilustrado O Mequetrefe, 1875-1889

    Directory of Open Access Journals (Sweden)

    Aristeu Elisandro Machado Lopes

    2011-12-01

    Full Text Available O periódico ilustrado O Mequetrefe iniciou sua circulação no Rio de Janeiro em 1875 e manteve suas atividades até janeiro de 1893. No transcurso de sua trajetória, os temas políticos se sobressaíram tratados em irreverentes ilustrações e em textos de opinião. Em suas páginas foram noticiadas as principais mudanças políticas ocorridas no Brasil Imperial, como a Abolição dos Escravos e o fim do Império com o advento republicano. O Mequetrefe publicou, ao longo de seus anos de atuação, notícias e opiniões sobre o ideário republicano difundido por seus adeptos na Corte. Já no final dos anos 1880, o jornal defendia a mudança de governo no Brasil com a República. O objetivo principal deste artigo é, portanto, averiguar quais as considerações deste periódico que foram dirigidas à questão republicana até a Proclamação da República. Outro assunto a ser tratado aqui é como a República - por meio do emprego das alegorias femininas e seus propagandistas - surgiu nas produções artísticas dos desenhistas e nas opiniões dos colaboradores do jornal, que igualmente se dedicavam ao humor e a sátira.

  7. Effect of curing ingredients and vacuum packaging on the physicochemical and storage quality of ready-to-eat Vawksa rep (smoked pork product during refrigerated storage

    Directory of Open Access Journals (Sweden)

    Deepshikha Deuri

    2016-06-01

    Full Text Available Aim: The present study was conducted for the development of ready-to-eat Vawksa rep (smoked pork product and to study the synergistic effect of curing ingredients and vacuum packaging on the physico-chemical and storage quality during refrigerated storage at (4°C±1°C for 15 days. Materials and Methods: Four different batches of Vawksa rep samples were prepared, i.e., T-1 (uncured, first cooked at 121°C for 15 min, and then smoked at 120°C for 30 min, T-2 (uncured, cooked, and smoked simultaneously at 120°C for 45 min, T-3 (cured, first cooked at 121°C for 15 min, and then smoked at 120°C for 30 min, and T-4 (cured, cooked, and smoked simultaneously at 120°C for 45 min. Results: Cooking yield was significantly higher (p<0.05 for the T-4. The pH of T-3 and T-4 samples was significantly higher (p<0.05 on day 15. The tyrosine value of all the samples increased significantly (p<0.05 among the different days of analysis. Thiobarbituric acid value was significantly (p<0.05 lower in T-3 sample both at the beginning and at the end of storage period. In microbiological profile, total plate count was lower in T-3 and T-4 than T-1 and T-2. However, Escherichia coli count was negative for T-3 and T-4 samples throughout the storage period. Among sensory attributes, T-3 and T-4 samples registered superior scores for color, flavor, texture, juiciness, and overall acceptability. Conclusion: Furthermore, Vawksa rep (smoked pork product could be prepared easily with little technology up-gradation and with a negligible escalation of production cost.

  8. Computational statistical mechanics

    CERN Document Server

    Hoover, WG

    1991-01-01

    Computational Statistical Mechanics describes the use of fast computers to simulate the equilibrium and nonequilibrium properties of gases, liquids, and solids at, and away from equilibrium. The underlying theory is developed from basic principles and illustrated by applying it to the simplest possible examples. Thermodynamics, based on the ideal gas thermometer, is related to Gibb's statistical mechanics through the use of Nosé-Hoover heat reservoirs. These reservoirs use integral feedback to control temperature. The same approach is carried through to the simulation and anal

  9. Statistics II essentials

    CERN Document Server

    Milewski, Emil G

    2012-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Statistics II discusses sampling theory, statistical inference, independent and dependent variables, correlation theory, experimental design, count data, chi-square test, and time se

  10. Statistics As Principled Argument

    CERN Document Server

    Abelson, Robert P

    2012-01-01

    In this illuminating volume, Robert P. Abelson delves into the too-often dismissed problems of interpreting quantitative data and then presenting them in the context of a coherent story about one's research. Unlike too many books on statistics, this is a remarkably engaging read, filled with fascinating real-life (and real-research) examples rather than with recipes for analysis. It will be of true interest and lasting value to beginning graduate students and seasoned researchers alike. The focus of the book is that the purpose of statistics is to organize a useful argument from quantitative

  11. Elementary Statistics Tables

    CERN Document Server

    Neave, Henry R

    2012-01-01

    This book, designed for students taking a basic introductory course in statistical analysis, is far more than just a book of tables. Each table is accompanied by a careful but concise explanation and useful worked examples. Requiring little mathematical background, Elementary Statistics Tables is thus not just a reference book but a positive and user-friendly teaching and learning aid. The new edition contains a new and comprehensive "teach-yourself" section on a simple but powerful approach, now well-known in parts of industry but less so in academia, to analysing and interpreting process dat

  12. Bayesian statistics an introduction

    CERN Document Server

    Lee, Peter M

    2012-01-01

    Bayesian Statistics is the school of thought that combines prior beliefs with the likelihood of a hypothesis to arrive at posterior beliefs. The first edition of Peter Lee’s book appeared in 1989, but the subject has moved ever onwards, with increasing emphasis on Monte Carlo based techniques. This new fourth edition looks at recent techniques such as variational methods, Bayesian importance sampling, approximate Bayesian computation and Reversible Jump Markov Chain Monte Carlo (RJMCMC), providing a concise account of the way in which the Bayesian approach to statistics develops as wel

  13. Sexo y Modernidad en la España de la Segunda República. Los discursos de la ciencia

    Directory of Open Access Journals (Sweden)

    Huertas, Rafael

    2013-12-01

    Full Text Available The aim of this article is to explore the scientific content of the “sexual reform” movement which took place in Spain during the 1920s and 1930s, culminating during the Second Republic. It covers three essential aspects of this subject: 1 the introduction of the new science of sexology; 2 the interest in sex education for children; and 3 the passing of new marriage legislation (the Divorce Law of 1932. Areas of scientific discourse are identified, associated with a “modernization” of mores and based on secular and progressive assumptions. The conflict between biological or endocrinological approaches and psychoanalytical methods is discussed, with encouragement of a healthy, aware experience of sexuality becoming established as the central argument. Issues such as responsible parenting, birth control, prevention of mental disorders (linked to traumatic sexual experiences, etc. are analysed in the light of medical, psychological and legal sources, in relation to the reform of sexual mores and overcoming the bourgeois moral double standardEste artículo pretende estudiar los contenidos científicos del movimiento de “reforma sexual” que tuvo lugar en España en los años veinte y treinta y que culminó durante la Segunda República. Se abordan, al respecto, tres aspectos fundamentales: 1 la introducción de la nueva ciencia sexológica; 2 el interés por la educación sexual de los niños; y 3 la promulgación de una nueva legislación matrimonial (la ley de divorcio de 1932. Se identifican discursos científicos, asimilados a una “modernización” de las costumbres, siempre desde presupuestos laicos y progresistas. Se apunta la confrontación entre enfoques biologicistas o endocrinológicos y planteamientos psicoanalíticos, estableciéndose como eje argumental el fomento de una vivencia consciente y sana de la sexualidad. Temas como paternidad responsable, control de la natalidad, prevención de los trastornos mentales (ligados a

  14. Análisis de la industria automotriz colombiana frente al Tratado de Libre Comercio con la República de Corea

    OpenAIRE

    Guevara Agudelo, Daniela Stephanie; Millán Aguado, Juan Sebastián; Rubio Castillo, Angely Marcela

    2014-01-01

    Mediante este proyecto, se hace un análisis de la industria automotriz en Colombia, cómo se puede ver afectada y cuáles serán los pros y contras ante la puesta en ejecución del Tratado de Libre Comercio con la República de Corea, tomando como base diferentes agentes que incursionan directamente en la industria mencionada, como lo son sus consumidores, los comerciantes, productores (ensambladoras) y el gobierno nacional. Igualmente, la globalización como aspecto fundamental para las econom...

  15. Arte, solidaridad y desarrollo: entrevista a Ricardo Calero, escultor, en torno al proyecto 'Espacio para un sueño' (República dominicana)

    OpenAIRE

    Alario Trigueros, María Teresa

    2006-01-01

    Esta entrevista al escultor zaragozano Ricardo Calero, recoge la experiencia desarrollada en el año 2000, en algunas de las regiones más deprimidas de la República Dominicana, en la que colaboraron una treintena de artistas de reconocido prestigio procedentes de diversas partes del mundo. Ricardo Calero narra, en primera persona, su vivencia en este proyecto al que se denominó El arte como herramienta para crear desarrollo, y sus experiencias en San José de Ocoa. Allí, en colaboración con los...

  16. O sertanejo além-mar : identidade regional e imigração goiana na República da Irlanda

    OpenAIRE

    Reijane Pinheiro da Silva

    2011-01-01

    A partir da análise de um fluxo emigratório de brasileiros de Goiás em direção à República da Irlanda, esta tese tem como objetivo compreender como os elementos da identidade regional desses imigrantes são reforçados, negociados ou negados no contexto da vida no exterior. Procurei, ainda, entender como essa experiência impacta as leituras que esses sujeitos fazem do lugar ao qual pertencem e dos lugares pelos quais transitam. A etnografia e a coleta de dados foram realizadas no Brasil e na Ir...

  17. Producción, tecnología y trabajo en la Rivera de Potosí durante la República temprana

    OpenAIRE

    Platt, Tristan

    2015-01-01

    La minería boliviana de la plata durante la República temprana (1825-1850) suele considerarse como inmersa en un estado de estancamiento cuando los altos precios del azogue, la falta de créditos y el monopolio estatal del rescate de la plata mantenían casi paralizada la industria potosina. Según esta perspectiva, existía un “impuesto indirecto” sobre la minería en cuanto los marcos se cancelaban por el Banco de Rescates con pesos febles, cuyo valor intrínseco fue menor que el de los pesos fue...

  18. Inserción internacional en América Central y la República Dominica: Diagnóstico y desafíos

    OpenAIRE

    Sebastián Auguste; Stein, Ernesto H.

    2012-01-01

    El presente estudio analiza el crecimiento reciente de las exportaciones de bienes y servicios de Centroamérica (excepto México) y la República Dominicana durante la década de 2000, con vistas a explicar a qué se debe la pérdida de participación de las exportaciones regionales en el comercio mundial. Los resultados encontrados muestran que distintos componentes actuaron de manera adversa: la especialización inicial no fue favorable para la región (los productos y regiones en los cuales se esp...

  19. A estação arqueológica de Salamansa (ilha de São Vicente, República de Cabo Verde)

    OpenAIRE

    Cardoso, João Luís; Soares, A. M. Monge

    2010-01-01

    Apresentam‑se os principais resultados obtidos nas duas missões arqueológicas patrocinadas pelo Centro Português de Actividades Subaquáticas (CPAS) à ilha de São Vicente (República de Cabo Verde), em 1998 e em 2005. Em 1998, confirmou‑se o efectivo interesse arqueológico do sítio, localizado sobre o mar, em local abrigado da vasta baía de Salamansa, situada na parte setentrional da ilha, tendo‑se registado a respectiva extensão e estratigrafia e procedido à colheita de amostras para datação. ...

  20. Homonota fasciata Duméril y Bibron, 1839 (Reptilia, Squamata, Phyllodactylidae. Primer registro para la provincia de Corrientes (República Argentina

    Directory of Open Access Journals (Sweden)

    Falcione, Camila

    2011-05-01

    Full Text Available Homonota fasciata Duméril & Bibron, 1839. República Argentina, Provincia de Corrientes, Departamento Bella Vista, Cuarta Sección, Colonia Progreso, Loma Sur, Toropí (28°35'55" S; 59°03'38" W (Figura 1. Colectores: Eduardo Etchepare, María del Rosario Ingaramo, Camila Falcione y Roberto Aguirre. 05 de abril de 2011. Se colectaron 4 ejemplares adultos (2 machos y 2 hembras y 1 juvenil, depositados en la Colección Herpetológica de la Universidad Nacional del Nordeste (UNNEC-11212, UNNEC-11213, UNNEC- 11214, UNNEC-11215 y UNNEC-11216.

  1. Direito administrativo e democracia : a interdependência entre interesses públicos e privados na Constituição da República de 1988

    OpenAIRE

    Fischgold, Bruno

    2011-01-01

    O princípio da supremacia do interesse público sobre o interesse privado foi considerado pela doutrina, durante muitos anos, o elemento normativo chave do regime jurídico administrativo no Brasil. No entanto, importantes autores vêm, recentemente, questionando a compatibilidade desse princípio com os preceitos fundamentais adotados pela Constituição da República de 1988. O objetivo do presente trabalho é tomar uma posição consistente nessa controvérsia, analisando o princípio da supremacia...

  2. Análisis de las posibilidades de exportación de productos agropecuarios colombianos hacia la República de Corea

    OpenAIRE

    Gutierrez Jiménez, Ana Maria; Riaño Méndez, Diego Felipe

    2013-01-01

    El comercio internacional es básico para el desarrollo económico de algunos países, en la actualidad los tratados de libre comercio son un recurso que se utiliza actualmente en muchos países para poder obtener beneficios económicos. Dado que se firmó en 2013 el tratado de libre comercio entre Colombia y la República de Corea surgió un interés por desarrollar un trabajo investigativo, debido a los pocos que se han realizado con respecto a este tema, que tratara las oportunidades que le sur...

  3. La integración en un sistema de bibliotecas de la Universidad de la República: una mirada desde las políticas educativas universitarias

    Directory of Open Access Journals (Sweden)

    Isabel Madrid

    2013-12-01

    Full Text Available Se presenta una historia de los intentos de integración en un sistema de las bibliotecas de la Universidad de la República, con énfasis en el período que se inicia en 2003-2004, a partir de la conformación de la Subcomisión de Bibliotecas en el ámbito del Prorrectorado de Gestión Administrativa.Se intenta analizar el proceso en términos de políticas públicas de educación superior.

  4. La huelga política. Análisis de su viabilidad en el ordenamiento jurídico en la República Oriental del Uruguay

    Directory of Open Access Journals (Sweden)

    Eduardo Goldstein

    2014-06-01

    Full Text Available Distintas motivaciones han llevado a los trabajadores agremiados a ejercer este derecho fun- damental reconocido por el Art. 57 de la Constitución de la República Oriental del Uruguay, los cuales han sido objeto de debates doctrinarios cuando las huelgas incursionan dentro de las de- nominadas atípicas. En el presente estudio analizamos su viabilidad cuando la misma tiene mo- tivaciones políticas y que respuesta da a ese fenómeno el ordenamiento jurídico patrio

  5. Las vicisitudes de la Primera República en Colombia (1810-1816. La interpretación centralista de nuestro proceso de Independencia

    Directory of Open Access Journals (Sweden)

    Ricardo Zuluaga Gil

    2012-01-01

    Full Text Available Este artículo se ocupa de una de las cuestiones menos estudiadas en la nuestra historia constitucional. Se trata del proceso de formación y colapso de la llamada Primera República, etapa que se desarrolló entre 1811 y 1816. El documento destaca el espíritu altamente federativo que caracterizó a ese momento, lo cual desmitifica el acento altamente unitario y nacional que la historiografía tradicional le ha dado a ese proceso.

  6. La europeización de la República de Moldova: un camino sinuoso e incierto hacia la integración europea

    Directory of Open Access Journals (Sweden)

    Aurelia Dercaci

    2014-01-01

    Full Text Available Después de la proclamación de la independencia en 1991, la República de Moldova (RM ha declarado su firme determinación de emprender su camino hacia Europa, a la que se siente identificada culturalmente. Aunque en las declaraciones y documentos adoptados el Estado nunca ha renunciado a este objetivo, ciertas acciones de sus líderes políticos parecen contradecir dicho compromiso. El trabajo tiene como objetivo analizar el proceso de evolución de la República de Moldova a la Unión Europea (UE, los compromisos asumidos por ambos y su cumplimiento. Además, voy a comparar los progresos realizados por Ucrania y RM hacia el acercamiento a la Unión Europea en los últimos años. Hace algunos años, Ucrania fue el país oriental con la perspectiva fundamental de la futura integración en la UE debido a sus cambios democráticos, hoy República de Moldova ha demostrado ser capaz de hacer más progresos en la promoción de la democracia y la aplicación de las reformas de gobernanza que Ucrania. Por otro lado, la relación entre la RM y la UE sigue siendo influenciada por las medidas adoptadas por la Federación de Rusia en la región donde todavía tiene influencia significativa, y tratar de mantener su presencia. Una de las herramientas fuertes de la influencia es la dependencia del suministro de energía y su falta de diversificación. El conflicto sin resolver de Transnistria es otro factor determinante de la falta de certeza en el proceso de europeización de la RM. El trabajo tiene como objetivo analizar la eficiencia de la europeización de la República de Moldova a través de la Política de Vecindad Europea, utilizando un método combinado constructivista y racionalista.

  7. Moneda y esencia. Una reflexión sobre economía y metafísica en la República de Platón

    Directory of Open Access Journals (Sweden)

    Alfonso Flórez

    2012-01-01

    Full Text Available Se indaga la relación que se da en la República entre los dos significados de ousia: como propiedad en el sentido de posesiones y riqueza, o en el sentido de esencia o sustancia. Aparte de las relaciones económicas asociadas al préstamo, al intercambio y al interés, se examina la función que, respecto de la ousia, cumple la moneda en la economía como recurso para disociar la riqueza de las posesiones, con lo cual logra un nivel de universalidad y equivalencia equiparable al del propio ser.

  8. The replicator of the nopaline-type Ti plasmid pTiC58 is a member of the repABC family and is influenced by the TraR-dependent quorum-sensing regulatory system.

    Science.gov (United States)

    Li, P L; Farrand, S K

    2000-01-01

    The replicator (rep) of the nopaline-type Ti plasmid pTiC58 is located adjacent to the trb operon of this conjugal element. Previous genetic studies of this region (D. R. Gallie, M. Hagiya, and C. I. Kado, J. Bacteriol. 161:1034-1041, 1985) identified functions involved in partitioning, origin of replication and incompatibility, and copy number control. In this study, we determined the nucleotide sequence of a 6,146-bp segment that encompasses the rep locus of pTiC58. The region contained four full open reading frames (ORFs) and one partial ORF. The first three ORFs, oriented divergently from the traI-trb operon, are closely related to the repA, repB, and repC genes of the octopine-type Ti plasmid pTiB6S3 as well as to other repA, -B, and -C genes from the Ri plasmid pRiA4b and three large plasmids from Rhizobium spp. The fourth ORF and the partial ORF are similar to y4CG and y4CF, respectively, of the Sym plasmid pNGR234a. The 363-bp intergenic region between traI and repA contained two copies of the tra box which is the cis promoter recognition site for TraR, the quorum-sensing activator of Ti plasmid conjugal transfer. Expression of the traI-trb operon from the tra box II-associated promoter mediated by TraR and its acyl-homoserine lactone ligand, AAI, was negatively influenced by an intact tra box III. On the other hand, the region containing the two tra boxes was required for maximal expression of repA, and this expression was enhanced slightly by TraR and AAI. Copy number of a minimal rep plasmid increased five- to sevenfold in strains expressing traR but only when AAI also was provided. Consistent with this effect, constitutive expression of the quorum-sensing system resulted in an apparent increase in Ti plasmid copy number. We conclude that Ti plasmid copy number is influenced by the quorum-sensing system, suggesting a connection between conjugal transfer and vegetative replication of these virulence elements.

  9. Whither Statistics Education Research?

    Science.gov (United States)

    Watson, Jane

    2016-01-01

    This year marks the 25th anniversary of the publication of a "National Statement on Mathematics for Australian Schools", which was the first curriculum statement this country had including "Chance and Data" as a significant component. It is hence an opportune time to survey the history of the related statistics education…

  10. Elementary statistical physics

    CERN Document Server

    Kittel, C

    1965-01-01

    This book is intended to help physics students attain a modest working knowledge of several areas of statistical mechanics, including stochastic processes and transport theory. The areas discussed are among those forming a useful part of the intellectual background of a physicist.

  11. Statistically Valid Planting Trials

    Science.gov (United States)

    C. B. Briscoe

    1961-01-01

    More than 100 million tree seedlings are planted each year in Latin America, and at least ten time'that many should be planted Rational control and development of a program of such magnitude require establishing and interpreting carefully planned trial plantings which will yield statistically valid answers to real and important questions. Unfortunately, many...

  12. Indiana forest statistics.

    Science.gov (United States)

    W. Brad Smith; Mark F. Golitz

    1988-01-01

    The third inventory of Indiana's timber resource shows that timberland area in Indiana climbed from 3.9 to 4.3 million acres between 1967 and 1986, an increase of more than 10%. During the same period growing-stock volume increased 43%. Highlights and statistics are presented on area, volume, growth, mortality, and removals.

  13. Illinois forest statistics, 1985.

    Science.gov (United States)

    Jerold T. Hahn

    1987-01-01

    The third inventory of the timber resource of Illinois shows a 1% increase in commercial forest area and a 40% gain in growing-stock volume between 1962 and 1985. Presented are highlights and statistics on area, volume, growth, mortality, removals, utilization, and biomass.

  14. Statistical air quality mapping

    NARCIS (Netherlands)

    Kassteele, van de J.

    2006-01-01

    This thesis handles statistical mapping of air quality data. Policy makers require more and more detailed air quality information to take measures to improve air quality. Besides, researchers need detailed air quality information to assess health effects. Accurate and spatially highly resolved maps

  15. Michigan forest statistics, 1980.

    Science.gov (United States)

    Gerhard K. Raile; W. Brad Smith

    1983-01-01

    The fourth inventory of the timber resource of Michigan shows a 7% decline in commercial forest area and a 27% gain in growing-stock volume between 1966 and 1980. Highlights and statistics are presented on area, volume, growth, mortality, removals, utilization, and biomass.

  16. Simple Statistics: - Summarized!

    Science.gov (United States)

    Blai, Boris, Jr.

    Statistics are an essential tool for making proper judgement decisions. It is concerned with probability distribution models, testing of hypotheses, significance tests and other means of determining the correctness of deductions and the most likely outcome of decisions. Measures of central tendency include the mean, median and mode. A second…

  17. Revising Educational Statistics.

    Science.gov (United States)

    Banner, James M., Jr.

    When gathering and presenting educational statistics, five principles should be considered. (1) The data must be accurate, valid, and complete. Limitations, weaknesses, margins of error, and levels of confidence should be clearly stated. (2) The data must include comparable information, sought in comparable ways, in comparable forms, from…

  18. The Pleasures of Statistics

    CERN Document Server

    Mosteller, Frederick; Hoaglin, David C; Tanur, Judith M

    2010-01-01

    Includes chapter-length insider accounts of work on the pre-election polls of 1948, statistical aspects of the Kinsey report on sexual behavior in the human male, mathematical learning theory, authorship of the disputed Federalist papers, safety of anesthetics, and an examination of the Coleman report on equality of educational opportunity

  19. Selected Outdoor Recreation Statistics.

    Science.gov (United States)

    Bureau of Outdoor Recreation (Dept. of Interior), Washington, DC.

    In this recreational information report, 96 tables are compiled from Bureau of Outdoor Recreation programs and surveys, other governmental agencies, and private sources. Eight sections comprise the document: (1) The Bureau of Outdoor Recreation, (2) Federal Assistance to Recreation, (3) Recreation Surveys for Planning, (4) Selected Statistics of…

  20. Statistics for Learning Genetics

    Science.gov (United States)

    Charles, Abigail Sheena

    2012-01-01

    This study investigated the knowledge and skills that biology students may need to help them understand statistics/mathematics as it applies to genetics. The data are based on analyses of current representative genetics texts, practicing genetics professors' perspectives, and more directly, students' perceptions of, and performance in, doing…

  1. Fisher's Contributions to Statistics

    Indian Academy of Sciences (India)

    its applications, especially to agriculture and the design of experiments therein. His contributions to statistics are so many that it is not even possible to mention them all in this short article. We, therefore, confine our attention to discussing what we regard as the more important among them. Fisher provided a unified and ...

  2. Statistical Hadronization and Holography

    DEFF Research Database (Denmark)

    Bechi, Jacopo

    2009-01-01

    In this paper we consider some issues about the statistical model of the hadronization in a holographic approach. We introduce a Rindler like horizon in the bulk and we understand the string breaking as a tunneling event under this horizon. We calculate the hadron spectrum and we get a thermal...

  3. La estrategia diplomática de Felipe II frente a la Tercera Elección Libre en La República Polaco-Lituana, 1586-1589

    Directory of Open Access Journals (Sweden)

    Matylda URJASZ-RACZKO

    2014-12-01

    Full Text Available El periodo de las primeras elecciones libres en la República polaco-lituana (1572-1589 fue un tiempo especial, tanto por los cambios de régimen dentro el país como por la intensificación de los contactos internacionales. Son conocidas las misiones políticas españolas en la República y las actuaciones de los diplomáticos españoles en la corte imperial con el propósito de imponer a un Habsburgo en el trono de la República. Sin embargo el análisis de la documentación diplomática española muestra que la corte imperial no fue el único lugar, como hasta ahora se había pensado, donde la diplomacia española realizó actividades con respecto al llamado «negocio de Polonia». La diplomacia de Felipe II carecía de herramientas de actuación en la República, por eso operaba donde tenían medios, tanto a través de su embajada en el imperio como en Roma. Todo ello muestra la necesidad de investigar las relaciones entre la República y Monarquía Hispánica dentro de una perspectiva internacional, en vez de solo la bilateral.

  4. Diversidad y abundancia relativa de corales, octocorales y esponjas en el Parque Nacional Jaragua, República Dominicana

    Directory of Open Access Journals (Sweden)

    Ernesto Weil

    2006-06-01

    Full Text Available El Parque Nacional Jaragua está localizado en un área remota al SW de la República Dominicana. La actividad humana se limita a pesquerías y minería. Las principales formaciones arrecifales incluyen (a arrecifes de banco (montículo creciendo sobre la plataforma en bandas paralelas, separadas por canales de arena y en dirección SE - NW, entre 12 y 25 m de profundidad, (b arrecifes de franja profundos que se desarrollan en los bordes de la plataforma entre 10 y 45 m de profundidad, y (c parches arrecifales y comunidades coralinas con poca o ninguna estructura arrecifal en áreas cercanas a la costa y plataformas someras. Nueve localidades fueron muestreadas intensivamente entre Cabo Beata y Bahía Honda mediante buceo autónomo. Se nadó en un patrón de zig-zag (50 m a cada lado desde el fondo (30 m hasta la zona somera en los arrecifes frangeantes. Se uso el mismo patrón pero a lo largo (por 500 m cubriendo el ancho de las bandas en los arrecifes de montículo. Las abundancias relativas y la diversidad de corales escleractínidos, octocorales y esponjas se estimaron en estas bandas. Las esponjas presentaron la mayor diversidad con 83 especies en 50 géneros, seguidas por los corales escleractínidos con 56 especies en 26 géneros y los octocorales con 47 especies en 15 géneros. Nuevos registros para el área incluyen ocho especies de corales, 21 de octocorales y 59 de esponjas. La diversidad, abundancia y distribución de especies de cada grupo varió entre localidades. En general, las localidades del norte y la isla de Los Frailes mar afuera, mostraron las mayores diversidades y abundancias de los tres grupos. En general, el Parque Nacional Jaragua presenta las diversidades más altas de corales, octocorales y esponjas registradas para la República Dominicana y están entre las más diversas para el norte del Caribe. Se recomienda una protección integral del área que incluya una regulación substancial (o prohibición de las

  5. The Statistical Drake Equation

    Science.gov (United States)

    Maccone, Claudio

    2010-12-01

    We provide the statistical generalization of the Drake equation. From a simple product of seven positive numbers, the Drake equation is now turned into the product of seven positive random variables. We call this "the Statistical Drake Equation". The mathematical consequences of this transformation are then derived. The proof of our results is based on the Central Limit Theorem (CLT) of Statistics. In loose terms, the CLT states that the sum of any number of independent random variables, each of which may be ARBITRARILY distributed, approaches a Gaussian (i.e. normal) random variable. This is called the Lyapunov Form of the CLT, or the Lindeberg Form of the CLT, depending on the mathematical constraints assumed on the third moments of the various probability distributions. In conclusion, we show that: The new random variable N, yielding the number of communicating civilizations in the Galaxy, follows the LOGNORMAL distribution. Then, as a consequence, the mean value of this lognormal distribution is the ordinary N in the Drake equation. The standard deviation, mode, and all the moments of this lognormal N are also found. The seven factors in the ordinary Drake equation now become seven positive random variables. The probability distribution of each random variable may be ARBITRARY. The CLT in the so-called Lyapunov or Lindeberg forms (that both do not assume the factors to be identically distributed) allows for that. In other words, the CLT "translates" into our statistical Drake equation by allowing an arbitrary probability distribution for each factor. This is both physically realistic and practically very useful, of course. An application of our statistical Drake equation then follows. The (average) DISTANCE between any two neighboring and communicating civilizations in the Galaxy may be shown to be inversely proportional to the cubic root of N. Then, in our approach, this distance becomes a new random variable. We derive the relevant probability density

  6. Statistical theory and inference

    CERN Document Server

    Olive, David J

    2014-01-01

    This text is for  a one semester graduate course in statistical theory and covers minimal and complete sufficient statistics, maximum likelihood estimators, method of moments, bias and mean square error, uniform minimum variance estimators and the Cramer-Rao lower bound, an introduction to large sample theory, likelihood ratio tests and uniformly most powerful  tests and the Neyman Pearson Lemma. A major goal of this text is to make these topics much more accessible to students by using the theory of exponential families. Exponential families, indicator functions and the support of the distribution are used throughout the text to simplify the theory. More than 50 ``brand name" distributions are used to illustrate the theory with many examples of exponential families, maximum likelihood estimators and uniformly minimum variance unbiased estimators. There are many homework problems with over 30 pages of solutions.

  7. Visuanimation in statistics

    KAUST Repository

    Genton, Marc G.

    2015-04-14

    This paper explores the use of visualization through animations, coined visuanimation, in the field of statistics. In particular, it illustrates the embedding of animations in the paper itself and the storage of larger movies in the online supplemental material. We present results from statistics research projects using a variety of visuanimations, ranging from exploratory data analysis of image data sets to spatio-temporal extreme event modelling; these include a multiscale analysis of classification methods, the study of the effects of a simulated explosive volcanic eruption and an emulation of climate model output. This paper serves as an illustration of visuanimation for future publications in Stat. Copyright © 2015 John Wiley & Sons, Ltd.

  8. Diffeomorphic Statistical Deformation Models

    DEFF Research Database (Denmark)

    Hansen, Michael Sass; Hansen, Mads/Fogtman; Larsen, Rasmus

    2007-01-01

    In this paper we present a new method for constructing diffeomorphic statistical deformation models in arbitrary dimensional images with a nonlinear generative model and a linear parameter space. Our deformation model is a modified version of the diffeomorphic model introduced by Cootes et al....... The modifications ensure that no boundary restriction has to be enforced on the parameter space to prevent folds or tears in the deformation field. For straightforward statistical analysis, principal component analysis and sparse methods, we assume that the parameters for a class of deformations lie on a linear...... manifold and that the distance between two deformations are given by the metric introduced by the L2-norm in the parameter space. The chosen L2-norm is shown to have a clear and intuitive interpretation on the usual nonlinear manifold. Our model is validated on a set of MR images of corpus callosum...

  9. Classical and statistical thermodynamics

    CERN Document Server

    Rizk, Hanna A

    2016-01-01

    This is a text book of thermodynamics for the student who seeks thorough training in science or engineering. Systematic and thorough treatment of the fundamental principles rather than presenting the large mass of facts has been stressed. The book includes some of the historical and humanistic background of thermodynamics, but without affecting the continuity of the analytical treatment. For a clearer and more profound understanding of thermodynamics this book is highly recommended. In this respect, the author believes that a sound grounding in classical thermodynamics is an essential prerequisite for the understanding of statistical thermodynamics. Such a book comprising the two wide branches of thermodynamics is in fact unprecedented. Being a written work dealing systematically with the two main branches of thermodynamics, namely classical thermodynamics and statistical thermodynamics, together with some important indexes under only one cover, this treatise is so eminently useful.

  10. General and Statistical Thermodynamics

    CERN Document Server

    Tahir-Kheli, Raza

    2012-01-01

    This textbook explains completely the general and statistical thermodynamics. It begins with an introductory statistical mechanics course, deriving all the important formulae meticulously and explicitly, without mathematical short cuts. The main part of the book deals with the careful discussion of the concepts and laws of thermodynamics, van der Waals, Kelvin and Claudius theories, ideal and real gases, thermodynamic potentials, phonons and all the related aspects. To elucidate the concepts introduced and to provide practical problem solving support, numerous carefully worked examples are of great value for students. The text is clearly written and punctuated with many interesting anecdotes. This book is written as main textbook for upper undergraduate students attending a course on thermodynamics.

  11. Cambodia; Statistical Appendix

    OpenAIRE

    International Monetary Fund

    2004-01-01

    In this study, the following statistical data are presented in detail: agriculture, livestock, and fishery production, structure of revenue, monetary survey, reserve money, interest rates, central government operations, profile of the commercial bank system, consumer price index, foreign debt, status of state-owned enterprises, proposed privatization standards, gross domestic product by expenditure at current prices, interest rates, budgetary expenditure by ministry, deflators for GDP by sect...

  12. Statistical Physics of Adaptation

    Science.gov (United States)

    2016-08-23

    system is indeed observed to be in II, then it will implicitly be distributed over the microstates available to it according to some new density... system , such that our choice of frequency for an external driving field determines the location of the peak in the resonance spectrum for a particle...Statistical Physics of Adaptation Nikolay Perunov, Robert A. Marsland, and Jeremy L. England Department of Physics, Physics of Living Systems Group

  13. Statistical classification of images

    OpenAIRE

    Giuliodori, María Andrea

    2011-01-01

    Image classification is a burgeoning field of study. Despite the advances achieved in this camp, there is no general agreement about what is the most effective methods for the classification of digital images. This dissertation contributes to this line of research by developing different statistical methods aim to classifying digital images. In Chapter 1 we introduce basic concepts of image classification and review some results and methodologies proposed previously in the literature. In Chap...

  14. Twin Prime Statistics

    Science.gov (United States)

    Dubner, Harvey

    2005-08-01

    Hardy and Littlewood conjectured that the number of twin primes less than x is asymptotic to 2 C_2 int_2^x dt/(log t)^2 where C_2 is the twin prime constant. This has been shown to give excellent results for x up to 10^16. This article presents statistics supporting the accuracy of the conjecture up to 10^600.

  15. Asymptotics in Quantum Statistics

    OpenAIRE

    Gill, Richard D.

    2004-01-01

    Observations or measurements taken of a quantum system (a small number of fundamental particles) are inherently random. If the state of the system depends on unknown parameters, then the distribution of the outcome depends on these parameters too, and statistical inference problems result. Often one has a choice of what measurement to take, corresponding to different experimental set-ups or settings of measurement apparatus. This leads to a design problem--which measurement is best for a give...

  16. Statistics I essentials

    CERN Document Server

    Milewski, Emil G

    2012-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Statistics I covers include frequency distributions, numerical methods of describing data, measures of variability, parameters of distributions, probability theory, and distributions.

  17. 1979 DOE statistical symposium

    Energy Technology Data Exchange (ETDEWEB)

    Gardiner, D.A.; Truett T. (comps. and eds.)

    1980-09-01

    The 1979 DOE Statistical Symposium was the fifth in the series of annual symposia designed to bring together statisticians and other interested parties who are actively engaged in helping to solve the nation's energy problems. The program included presentations of technical papers centered around exploration and disposal of nuclear fuel, general energy-related topics, and health-related issues, and workshops on model evaluation, risk analysis, analysis of large data sets, and resource estimation.

  18. Search Databases and Statistics

    DEFF Research Database (Denmark)

    Refsgaard, Jan C; Munk, Stephanie; Jensen, Lars J

    2016-01-01

    Advances in mass spectrometric instrumentation in the past 15 years have resulted in an explosion in the raw data yield from typical phosphoproteomics workflows. This poses the challenge of confidently identifying peptide sequences, localizing phosphosites to proteins and quantifying these from...... searches. Additionally, careful filtering and use of appropriate statistical tests on the output datasets affects the quality of all downstream analyses and interpretation of the data. Our considerations and general practices on these aspects of phosphoproteomics data processing are presented here....

  19. Novel RepA-MCM proteins encoded in plasmids pTAU4, pORA1 and pTIK4 from Sulfolobus neozealandicus

    DEFF Research Database (Denmark)

    Greve, B.; Jensen, S.; Phan, H.

    2005-01-01

    Three plasmids isolated from the crenarchaeal thermoacidophile Sulfolobus neozealandicus were characterized. Plasmids pTAU4 (7,192 bp), pORA1 (9,689 bp) and pTIK4 (13,638 bp) show unusual properties that distinguish them from previously characterized cryptic plasmids of the genus Sulfolobus....... Plasmids pORA1 and pTIK4 encode RepA proteins, only the former of which carries the novel polymerase-primase domain of other known Sulfolobus plasmids. Plasmid pTAU4 encodes a mini-chromosome maintenance protein homolog and no RepA protein; the implications for DNA replication are considered. Plasmid pORA1...... is the first Sulfolobus plasmid to be characterized that does not encode the otherwise highly conserved DNA-binding PlrA protein. Another encoded protein appears to be specific for the New Zealand plasmids. The three plasmids should provide useful model systems for functional studies of these important...

  20. Novel RepA-MCM proteins encoded in plasmids pTAU4, pORA1 and pTIK4 from Sulfolobus neozealandicus

    DEFF Research Database (Denmark)

    Greve, Bo Bjørn

    2005-01-01

    Three plasmids isolated from the crenarchaeal thermoacidophile Sulfolobus neozealandicus were characterized. Plasmids pTAU4 (7,192 bp), pORA1 (9,689 bp) and pTIK4 (13,638 bp) show unusual properties that distinguish them from previously characterized cryptic plasmids of the genus Sulfolobus....... Plasmids pORA1 and pTIK4 encode RepA proteins, only the former of which carries the novel polymerase–primase domain of other known Sulfolobus plasmids. Plasmid pTAU4 encodes a mini-chromosome maintenance protein homolog and no RepA protein; the implications for DNA replication are considered. Plasmid pORA1...... is the first Sulfolobus plasmid to be characterized that does not encode the otherwise highly conserved DNA-binding PlrA protein. Another encoded protein appears to be specific for the New Zealand plasmids. The three plasmids should provide useful model systems for functional studies of these important...

  1. Las enseñanzas de sordomudos durante la II República Española. Una perspectiva histórica

    Directory of Open Access Journals (Sweden)

    Alfredo ALCINA MADUEÑO

    2011-07-01

    Full Text Available Las enseñanzas de sordomudos en el periodo de la II República española es un tema poco estudiado e inédito en determinados aspectos. Se puede decir que participa de las características de la educación general de dicha etapa: esfuerzo económico y presupuestario de los gobiernos, renovación metodológica, modernización del sistema, ampliación de la red escolar, formación del magisterio, etc., si bien presenta una idiosincrasia muy marcada e incluso contradictoria, no solo por la conocida contraposición de los gobiernos de un bienio y otro (31/33 y 34/35, sino también por las decisiones de política educativa que se toman por los mismos gobiernos de la coalición republicano-socialista. El legado de la aportación republicana es más documental que de realizaciones concretas, y tendrá mayor aplicación en el régimen político que aniquila y sucede a la República que en ella misma. La consideración de fuentes primarias (legales y documentales fundamentan principalmente las conclusiones de esta exposición.

  2. Overdispersion in nuclear statistics

    Energy Technology Data Exchange (ETDEWEB)

    Semkow, Thomas M. [State University of New York, Albany, NY (United States)

    1999-02-11

    The modern statistical distribution theory is applied to the development of the overdispersion theory in ionizing-radiation statistics for the first time. The physical nuclear system is treated as a sequence of binomial processes, each depending on a characteristic probability, such as probability of decay, detection, etc. The probabilities fluctuate in the course of a measurement, and the physical reasons for that are discussed. If the average values of the probabilities change from measurement to measurement, which originates from the random Lexis binomial sampling scheme, then the resulting distribution is overdispersed. The generating functions and probability distribution functions are derived, followed by a moment analysis. The Poisson and Gaussian limits are also given. The distribution functions belong to a family of generalized hypergeometric factorial moment distributions by Kemp and Kemp, and can serve as likelihood functions for the statistical estimations. An application to radioactive decay with detection is described and working formulae are given, including a procedure for testing the counting data for overdispersion. More complex experiments in nuclear physics (such as solar neutrino) can be handled by this model, as well as distinguishing between the source and background.

  3. Testing statistical hypotheses

    CERN Document Server

    Lehmann, E L

    2005-01-01

    The third edition of Testing Statistical Hypotheses updates and expands upon the classic graduate text, emphasizing optimality theory for hypothesis testing and confidence sets. The principal additions include a rigorous treatment of large sample optimality, together with the requisite tools. In addition, an introduction to the theory of resampling methods such as the bootstrap is developed. The sections on multiple testing and goodness of fit testing are expanded. The text is suitable for Ph.D. students in statistics and includes over 300 new problems out of a total of more than 760. E.L. Lehmann is Professor of Statistics Emeritus at the University of California, Berkeley. He is a member of the National Academy of Sciences and the American Academy of Arts and Sciences, and the recipient of honorary degrees from the University of Leiden, The Netherlands and the University of Chicago. He is the author of Elements of Large-Sample Theory and (with George Casella) he is also the author of Theory of Point Estimat...

  4. Statistics for lawyers

    CERN Document Server

    Finkelstein, Michael O

    2015-01-01

    This classic text, first published in 1990, is designed to introduce law students, law teachers, practitioners, and judges to the basic ideas of mathematical probability and statistics as they have been applied in the law. The third edition includes over twenty new sections, including the addition of timely topics, like New York City police stops, exonerations in death-sentence cases, projecting airline costs, and new material on various statistical techniques such as the randomized response survey technique, rare-events meta-analysis, competing risks, and negative binomial regression. The book consists of sections of exposition followed by real-world cases and case studies in which statistical data have played a role. The reader is asked to apply the theory to the facts, to calculate results (a hand calculator is sufficient), and to explore legal issues raised by quantitative findings. The authors' calculations and comments are given in the back of the book. As with previous editions, the cases and case stu...

  5. R for statistics

    CERN Document Server

    Cornillon, Pierre-Andre; Husson, Francois; Jegou, Nicolas; Josse, Julie; Kloareg, Maela; Matzner-Lober, Eric; Rouviere, Laurent

    2012-01-01

    An Overview of RMain ConceptsInstalling RWork SessionHelpR ObjectsFunctionsPackagesExercisesPreparing DataReading Data from FileExporting ResultsManipulating VariablesManipulating IndividualsConcatenating Data TablesCross-TabulationExercisesR GraphicsConventional Graphical FunctionsGraphical Functions with latticeExercisesMaking Programs with RControl FlowsPredefined FunctionsCreating a FunctionExercisesStatistical MethodsIntroduction to the Statistical MethodsA Quick Start with RInstalling ROpening and Closing RThe Command PromptAttribution, Objects, and FunctionSelectionOther Rcmdr PackageImporting (or Inputting) DataGraphsStatistical AnalysisHypothesis TestConfidence Intervals for a MeanChi-Square Test of IndependenceComparison of Two MeansTesting Conformity of a ProportionComparing Several ProportionsThe Power of a TestRegressionSimple Linear RegressionMultiple Linear RegressionPartial Least Squares (PLS) RegressionAnalysis of Variance and CovarianceOne-Way Analysis of VarianceMulti-Way Analysis of Varian...

  6. Brain Aneurysm Statistics and Facts

    Science.gov (United States)

    ... Statistics and Facts A- A A+ Brain Aneurysm Statistics and Facts An estimated 6 million people in ... Understanding the Brain Warning Signs/ Symptoms Brain Aneurysm Statistics and Facts Seeking Medical Attention Risk Factors Aneurysm ...

  7. Realidad de la cirugía cardíaca en la República Argentina. Registro CONAREC XVI

    Directory of Open Access Journals (Sweden)

    Diego M. Lowenstein Haber

    2010-01-01

    Full Text Available RESUMENIntroducciónLos dos grandes registros multicéntricos de cirugía cardíaca realizados en la Argentina,CONAREC y ESMUCICA, datan de más de 10 años. Considerando los avances médicosy quirúrgicos de la última década, surgió la necesidad de realizar un nuevo registronacional, prospectivo y multicéntrico para conocer las características, la evolución, lascomplicaciones y los predictores de mortalidad de los pacientes sometidos a cirugía cardíaca.ObjetivosConocer el perfil epidemiológico, la modalidad quirúrgica y la evolución posoperatoria de lospacientes sometidos a cirugía cardíaca en la Argentina.Material y métodosRegistro prospectivo, consecutivo y multicéntrico realizado en 49 centros cardioquirúrgicosde la República Argentina por residentes de cardiología. Se analizaron las características yla evolución de 2.553 pacientes sometidos a cirugía cardíaca entre septiembre de 2007 yoctubre de 2008: 1.465 (57,4% a cirugía coronaria, 359 (14,1% a reemplazo valvular aórtico,169 (6,6% a cirugía valvular mitral, 312 (12,2% a cirugía combinada coronariovalvular y248 (9,7% a otros procedimientos.ResultadosHubo predominio de hombres (74,9%; la edad promedio fue de 63 ± 11 años. La prevalenciade diabetes fue del 24,9%, la de hipertensión del 76,3% y la de insuficiencia cardíaca del17%. La disfunción ventricular moderada a grave prequirúrgica fue del 23,8% y el 19,8% delas cirugías fueron no programadas.En las cirugías coronarias, el 41,9% de ellas se realizaron sin circulación extracorpórea y seempleó puente mamario en el 89%.El 81,7% de las cirugías mitrales se indicaron por insuficiencia y el 62,6% de las aórticas,por estenosis. En estas cirugías se emplearon válvulas mecánicas en el 58% de los casos.La mediana de internación fue de 6 días. Se presentaron complicaciones mayores en el31,7% (del 25% en coronarios al 49,36% en combinados y la mortalidad global fue del 7,7%(del 4,3% en coronarios al 13

  8. La cartografía colonial española durante la Segunda República (1931-1936

    Directory of Open Access Journals (Sweden)

    Urteaga, Luis

    2010-07-01

    Full Text Available The Spanish Second Republic set aside a big amount of resources, both human and economic, to survey the colonies. The consecutive republican governments kept a strong continuity on the schemes for colonial cartography, with no significant changes over the plans established in past periods. Cartographic work was focused in Morocco’s territory, and was carry out by a military unit named Comisión Geográfíca de Marruecos y Límites (Morocco’s Geographical Commission. This paper, built on primary sources, examines the institutional framework of Spanish colonial cartography during the republican period, identifies the leading mapmakers, and discusses the main cartographic surveys.

    La Segunda República dedicó cuantiosos recursos, económicos y humanos, a la cartografía de las posesiones coloniales. Los sucesivos gobiernos republicanos mantuvieron una fuerte continuidad, organizativa y funcional, en el ámbito de la cartografía colonial, sin que se detecte ningún cambio significativo respecto a los planes trazados en etapas anteriores. La actividad cartográfica continuó centrada en el territorio de Marruecos, y fue protagonizada por una unidad dependiente del Ministerio de la Guerra, la Comisión Geográfica de Marruecos y Límites. En este trabajo, que se apoya en fuentes primarias, se ofrece una descripción del marco institucional de la cartografía colonial durante el período republicano, se identifica a sus artífices, y se da cuenta de los levantamientos cartográficos realizados. [fr] La Deuxième République a consacré nombreux ressources, économiques et humains, à la cartographie des possessions coloniales. Les successifs gouvernements républicains ont tenu une forte continuité, d’organisation et fonctionnelle, dans le domaine de la cartographie coloniale, sans qu’on ne puisse détecter aucun changement significatif en relation aux plans tracés en étapes antérieures. L’activité cartographique a continu

  9. Beginning statistics with data analysis

    CERN Document Server

    Mosteller, Frederick; Rourke, Robert EK

    2013-01-01

    This introduction to the world of statistics covers exploratory data analysis, methods for collecting data, formal statistical inference, and techniques of regression and analysis of variance. 1983 edition.

  10. Statistical Methods for Studying Genetic Variation in Populations

    Science.gov (United States)

    2012-08-01

    France Israel Russia Algeria Angola S.Africa Kenya Nigeria Cent.Afr.Rep. Botswana Namibia Lesotho Senegal Congo B ra zi l C ol om bi a M ex ic o C am...Cambodia Japan China NewGuinea Pakistan India Italy France Israel Russia Algeria Angola S.Africa Kenya Nigeria Cent.Afr.Rep. Botswana Namibia Lesotho...an artificial selection experiment on Drosophila Melanogaster. Our experiments also suggest that sample size is an important factor in deter- mining

  11. Statistical Inference at Work: Statistical Process Control as an Example

    Science.gov (United States)

    Bakker, Arthur; Kent, Phillip; Derry, Jan; Noss, Richard; Hoyles, Celia

    2008-01-01

    To characterise statistical inference in the workplace this paper compares a prototypical type of statistical inference at work, statistical process control (SPC), with a type of statistical inference that is better known in educational settings, hypothesis testing. Although there are some similarities between the reasoning structure involved in…

  12. On quantum statistical inference

    DEFF Research Database (Denmark)

    Barndorff-Nielsen, Ole Eiler; Gill, Richard D.; Jupp, Peter E.

    Recent developments in the mathematical foundations of quantum mechanics have brought the theory closer to that of classical probability and statistics. On the other hand, the unique character of quantum physics sets many of the questions addressed apart from those met classically in stochastics....... Furthermore, concurrent advances in experimental techniques and in the theory of quantum computation have led to a strong interest in questions of quantum information, in particular in the sense of the amount of information about unknown parameters in given observational data or accessible through various...

  13. Statistics for Finance

    DEFF Research Database (Denmark)

    Lindström, Erik; Madsen, Henrik; Nielsen, Jan Nygaard

    that rarely connect concepts to data and books on econometrics and time series analysis that do not cover specific problems related to option valuation. The book discusses applications of financial derivatives pertaining to risk assessment and elimination. The authors cover various statistical...... and mathematical techniques, including linear and nonlinear time series analysis, stochastic calculus models, stochastic differential equations, Itō’s formula, the Black–Scholes model, the generalized method-of-moments, and the Kalman filter. They explain how these tools are used to price financial derivatives...

  14. Nonparametric statistical inference

    CERN Document Server

    Gibbons, Jean Dickinson

    2014-01-01

    Thoroughly revised and reorganized, the fourth edition presents in-depth coverage of the theory and methods of the most widely used nonparametric procedures in statistical analysis and offers example applications appropriate for all areas of the social, behavioral, and life sciences. The book presents new material on the quantiles, the calculation of exact and simulated power, multiple comparisons, additional goodness-of-fit tests, methods of analysis of count data, and modern computer applications using MINITAB, SAS, and STATXACT. It includes tabular guides for simplified applications of tests and finding P values and confidence interval estimates.

  15. Key World Energy Statistics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The IEA produced its first handy, pocket-sized summary of key energy data in 1997. This new edition responds to the enormously positive reaction to the book since then. Key World Energy Statistics produced by the IEA contains timely, clearly-presented data on supply, transformation and consumption of all major energy sources. The interested businessman, journalist or student will have at his or her fingertips the annual Canadian production of coal, the electricity consumption in Thailand, the price of diesel oil in Spain and thousands of other useful energy facts. It exists in different formats to suit our readers' requirements.

  16. Statistical mechanics of learning

    CERN Document Server

    Engel, Andreas

    2001-01-01

    The effort to build machines that are able to learn and undertake tasks such as datamining, image processing and pattern recognition has led to the development of artificial neural networks in which learning from examples may be described and understood. The contribution to this subject made over the past decade by researchers applying the techniques of statistical mechanics is the subject of this book. The authors provide a coherent account of various important concepts and techniques that are currently only found scattered in papers, supplement this with background material in mathematics and physics, and include many examples and exercises.

  17. Circular statistics in R

    CERN Document Server

    Pewsey, Arthur; Ruxton, Graeme D

    2013-01-01

    Circular Statistics in R provides the most comprehensive guide to the analysis of circular data in over a decade. Circular data arise in many scientific contexts whether it be angular directions such as: observed compass directions of departure of radio-collared migratory birds from a release point; bond angles measured in different molecules; wind directions at different times of year at a wind farm; direction of stress-fractures in concretebridge supports; longitudes of earthquake epicentres or seasonal and daily activity patterns, for example: data on the times of day at which animals are c

  18. Statistical fluid mechanics

    CERN Document Server

    Monin, A S

    2007-01-01

    ""If ever a field needed a definitive book, it is the study of turbulence; if ever a book on turbulence could be called definitive, it is this book."" - ScienceWritten by two of Russia's most eminent and productive scientists in turbulence, oceanography, and atmospheric physics, this two-volume survey is renowned for its clarity as well as its comprehensive treatment. The first volume begins with an outline of laminar and turbulent flow. The remainder of the book treats a variety of aspects of turbulence: its statistical and Lagrangian descriptions, shear flows near surfaces and free turbulenc

  19. Statistics in biomedical research

    Directory of Open Access Journals (Sweden)

    González-Manteiga, Wenceslao

    2007-06-01

    Full Text Available The discipline of biostatistics is nowadays a fundamental scientific component of biomedical, public health and health services research. Traditional and emerging areas of application include clinical trials research, observational studies, physiology, imaging, and genomics. The present article reviews the current situation of biostatistics, considering the statistical methods traditionally used in biomedical research, as well as the ongoing development of new methods in response to the new problems arising in medicine. Clearly, the successful application of statistics in biomedical research requires appropriate training of biostatisticians. This training should aim to give due consideration to emerging new areas of statistics, while at the same time retaining full coverage of the fundamentals of statistical theory and methodology. In addition, it is important that students of biostatistics receive formal training in relevant biomedical disciplines, such as epidemiology, clinical trials, molecular biology, genetics, and neuroscience.La Bioestadística es hoy en día una componente científica fundamental de la investigación en Biomedicina, salud pública y servicios de salud. Las áreas tradicionales y emergentes de aplicación incluyen ensayos clínicos, estudios observacionales, fisología, imágenes, y genómica. Este artículo repasa la situación actual de la Bioestadística, considerando los métodos estadísticos usados tradicionalmente en investigación biomédica, así como los recientes desarrollos de nuevos métodos, para dar respuesta a los nuevos problemas que surgen en Medicina. Obviamente, la aplicación fructífera de la estadística en investigación biomédica exige una formación adecuada de los bioestadísticos, formación que debería tener en cuenta las áreas emergentes en estadística, cubriendo al mismo tiempo los fundamentos de la teoría estadística y su metodología. Es importante, además, que los estudiantes de

  20. Who Needs Statistics? | Poster

    Science.gov (United States)

    You may know the feeling. You have collected a lot of new data on an important experiment. Now you are faced with multiple groups of data, a sea of numbers, and a deadline for submitting your paper to a peer-reviewed journal. And you are not sure which data are relevant, or even the best way to present them. The statisticians at Data Management Services (DMS) know how to help. This small group of experts provides a wide array of statistical and mathematical consulting services to the scientific community at NCI at Frederick and NCI-Bethesda.

  1. Functional and Operatorial Statistics

    CERN Document Server

    Dabo-niang, Sophie

    2008-01-01

    An increasing number of statistical problems and methods involve infinite-dimensional aspects. This is due to the progress of technologies which allow us to store more and more information while modern instruments are able to collect data much more effectively due to their increasingly sophisticated design. This evolution directly concerns statisticians, who have to propose new methodologies while taking into account such high-dimensional data (e.g. continuous processes, functional data, etc.). The numerous applications (micro-arrays, paleo- ecological data, radar waveforms, spectrometric curv

  2. Nanotechnology and statistical inference

    Science.gov (United States)

    Vesely, Sara; Vesely, Leonardo; Vesely, Alessandro

    2017-08-01

    We discuss some problems that arise when applying statistical inference to data with the aim of disclosing new func-tionalities. A predictive model analyzes the data taken from experiments on a specific material to assess the likelihood that another product, with similar structure and properties, will exhibit the same functionality. It doesn't have much predictive power if vari-ability occurs as a consequence of a specific, non-linear behavior. We exemplify our discussion on some experiments with biased dice.

  3. Associative Analysis in Statistics

    Directory of Open Access Journals (Sweden)

    Mihaela Muntean

    2015-03-01

    Full Text Available In the last years, the interest in technologies such as in-memory analytics and associative search has increased. This paper explores how you can use in-memory analytics and an associative model in statistics. The word “associative” puts the emphasis on understanding how datasets relate to one another. The paper presents the main characteristics of “associative” data model. Also, the paper presents how to design an associative model for labor market indicators analysis. The source is the EU Labor Force Survey. Also, this paper presents how to make associative analysis.

  4. International petroleum statistics report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The International Petroleum Statistics Report is a monthly publication that provides current international oil data. This report presents data on international oil production, demand, imports, exports and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). Section 2 presents an oil supply/demand balance for the world, in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries.

  5. Schatzki ring, statistically reexamined.

    Science.gov (United States)

    Pezzullo, John C; Lewicki, Ann M

    2003-09-01

    In the article by Schatzki published in 1963, data about the lower esophageal ring relate ring diameter to presence of dysphagia. Statistical analysis of these measurements was performed to quantify conclusions of Schatzki and to extract additional information from the data. Ring diameters in 332 patients with and without dysphagia are described in a histogram in the original article of Schatzki. Data were evaluated with analysis of variance, logistic regression, and receiver operating characteristic (ROC) analysis to quantify the relationship between ring diameter and dysphagia. Follow-up information was available in 36 symptomatic and 30 asymptomatic patients of Schatzki. Logistic regression indicated that there was a highly significant difference in ring diameter between the asymptomatic group and patients with recurrent dysphagia (P Schatzki had a 96% (104 of 108) sensitivity and a 58% (130 of 224) specificity, with area under the ROC curve of 0.888. Retrospective statistical analysis of original data of Schatzki validated his major conclusions about the data. Some important questions remain unanswered because of missing data in the study of Schatzki. Copyright RSNA, 2003

  6. Statistical clumped isotope signatures

    Science.gov (United States)

    Röckmann, T.; Popa, M. E.; Krol, M. C.; Hofmann, M. E. G.

    2016-01-01

    High precision measurements of molecules containing more than one heavy isotope may provide novel constraints on element cycles in nature. These so-called clumped isotope signatures are reported relative to the random (stochastic) distribution of heavy isotopes over all available isotopocules of a molecule, which is the conventional reference. When multiple indistinguishable atoms of the same element are present in a molecule, this reference is calculated from the bulk (≈average) isotopic composition of the involved atoms. We show here that this referencing convention leads to apparent negative clumped isotope anomalies (anti-clumping) when the indistinguishable atoms originate from isotopically different populations. Such statistical clumped isotope anomalies must occur in any system where two or more indistinguishable atoms of the same element, but with different isotopic composition, combine in a molecule. The size of the anti-clumping signal is closely related to the difference of the initial isotope ratios of the indistinguishable atoms that have combined. Therefore, a measured statistical clumped isotope anomaly, relative to an expected (e.g. thermodynamical) clumped isotope composition, may allow assessment of the heterogeneity of the isotopic pools of atoms that are the substrate for formation of molecules. PMID:27535168

  7. Statistical methods for forecasting

    CERN Document Server

    Abraham, Bovas

    2009-01-01

    The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists."This book, it must be said, lives up to the words on its advertising cover: ''Bridging the gap between introductory, descriptive approaches and highly advanced theoretical treatises, it provides a practical, intermediate level discussion of a variety of forecasting tools, and explains how they relate to one another, both in theory and practice.'' It does just that!"-Journal of the Royal Statistical Society"A well-written work that deals with statistical methods and models that can be used to produce short-term forecasts, this book has wide-ranging applications. It could be used in the context of a study of regression, forecasting, and time series ...

  8. International petroleum statistics report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    The International Petroleum Statistics Report is a monthly publication that provides current international oil data. This report is published for the use of Members of Congress, Federal agencies, State agencies, industry, and the general public. Publication of this report is in keeping with responsibilities given the Energy Information Administration in Public Law 95-91. The International Petroleum Statistics Report presents data on international oil production, demand, imports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1995; OECD stocks from 1973 through 1995; and OECD trade from 1985 through 1995.

  9. Experimental Mathematics and Computational Statistics

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, Jonathan M.

    2009-04-30

    The field of statistics has long been noted for techniques to detect patterns and regularities in numerical data. In this article we explore connections between statistics and the emerging field of 'experimental mathematics'. These includes both applications of experimental mathematics in statistics, as well as statistical methods applied to computational mathematics.

  10. Successful Establishment of Plasmids R1 and pMV158 in a New Host Requires the Relief of the Transcriptional Repression of Their Essential rep Genes

    Directory of Open Access Journals (Sweden)

    José Á. Ruiz-Masó

    2017-12-01

    Full Text Available Although differing in size, encoded traits, host range, and replication mechanism, both narrow-host-range theta-type conjugative enterobacterial plasmid R1 and promiscuous rolling-circle-type mobilizable streptococcal plasmid pMV158 encode a transcriptional repressor protein, namely CopB in R1 and CopG in pMV158, involved in replication control. The gene encoding CopB or CopG is cotranscribed with a downstream gene that encodes the replication initiator Rep protein of the corresponding plasmid. However, whereas CopG is an auto-repressor that inhibits transcription of the entire copG-repB operon, CopB is expressed constitutively and represses a second, downstream promoter that directs transcription of repA. As a consequence of the distinct regulatory pathways implied by CopB and CopG, these repressor proteins play a different role in control of plasmid replication during the steady state: while CopB has an auxiliary role by keeping repressed the regulated promoter whenever the plasmid copy number is above a low threshold, CopG plays a primary role by acting coordinately with RNAII. Here, we have studied the role of the regulatory circuit mediated by these transcriptional repressors during the establishment of these two plasmids in a new host cell, and found that excess Cop repressor molecules in the recipient cell result in a severe decrease in the frequency and/or the velocity of appearance of transformant colonies for the cognate plasmid but not for unrelated plasmids. Using the pMV158 replicon as a model system, together with highly sensitive real-time qPCR and inverse PCR methods, we have also analyzed the effect of CopG on the kinetics of repopulation of the plasmid in Streptococcus pneumoniae. We show that, whereas in the absence of CopG pMV158 repopulation occurs mainly during the first 45 min following plasmid transfer, the presence of the transcriptional repressor in the recipient cell severely impairs the replicon repopulation and makes

  11. República, nación y democracia ante el desafío de la diversidad Republic, nation and democracy against the challenge of diversity

    Directory of Open Access Journals (Sweden)

    Susana Villavicencio

    2010-12-01

    Full Text Available La República no es sólo el nombre de una nación estado y su régimen. Es también un modelo nacional de integración basado en la concepción universalista de la ciudadanía que afirma la figura abstracta de la persona jurídica, portadora de iguales derechos y obligaciones, y valores de civismo y civilidad. Este trabajo analiza cómo la emergencia de la diversidad cultural en Argentina pone en cuestión los conceptos modernos de república, nación y democracia. Examina asimismo cómo los legados de la república, que supone una visión homogeneizada de la diversidad, implican una ambivalencia entre la adhesión a principios universalistas de progreso de la humanidad y la realidad de una democracia excluyente que valorizaba una cultura por sobre otras. Se estudian las narrativas de la identidad nacional, mostrando cómo la oposición civilización -barbarie afecta la visión de los desafíos del futuro de la democracia en América Latina.Republic is not only the name of a nation and its regime. It is also a national model of integration based on a universalist conception of citizenship that sustains the abstract figure of the legal person, endowed with equal rights and obligations, and values of civism and civility, the foundation stones of a society that arises from a contract. This paper analyses how the emergency of the cultural diversity in Argentina calls into question modern political concepts like republic, nation and democracy. It is also evaluated how the republic's inheritance, which supposes an homogenized sight of diversity, gives rise to an ambivalence among the adherence to universalist principles of the progress of humanity and the reality of an excluding democracy that gave value to one culture above others. The narratives of national identity are studied describing how the opposition between civilization and barbariy affects the way Latin Americans see the great challenges presented by the future of democracy, and by the

  12. Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger.

    Science.gov (United States)

    Cousido-Siah, Alexandra; Ayoub, Daniel; Berberián, Graciela; Bollo, Mariana; Van Dorsselaer, Alain; Debaene, François; DiPolo, Reinaldo; Petrova, Tatiana; Schulze-Briese, Clemens; Olieric, Vincent; Esteves, Adriana; Mitschler, André; Sanglier-Cianférani, Sarah; Beaugé, Luis; Podjarny, Alberto

    2012-09-01

    The protein ReP1-NCXSQ was isolated from the cytosol of squid nerves and has been shown to be required for MgATP stimulation of the squid nerve Na(+)/Ca(2+) exchanger NCXSQ1. In order to determine its mode of action and the corresponding biologically active ligand, sequence analysis, crystal structures and mass-spectrometric studies of this protein and its Tyr128Phe mutant are reported. Sequence analysis suggests that it belongs to the CRABP family in the FABP superfamily. The X-ray structure at 1.28 Å resolution shows the FABP β-barrel fold, with a fatty acid inside the barrel that makes a relatively short hydrogen bond to Tyr128 and shows a double bond between C9 and C10 but that is disordered beyond C12. Mass-spectrometric studies identified this fatty acid as palmitoleic acid, confirming the double bond between C9 and C10 and establishing a length of 16 C atoms in the aliphatic chain. This acid was caught inside during the culture in Escherichia coli and therefore is not necessarily linked to the biological activity. The Tyr128Phe mutant was unable to activate the Na(+)/Ca(2+) exchanger and the corresponding crystal structure showed that without the hydrogen bond to Tyr128 the palmitoleic acid inside the barrel becomes disordered. Native mass-spectrometric analysis confirmed a lower occupancy of the fatty acid in the Tyr128Phe mutant. The correlation between (i) the lack of activity of the Tyr128Phe mutant, (ii) the lower occupancy/disorder of the bound palmitoleic acid and (iii) the mass-spectrometric studies of ReP1-NCXSQ suggests that the transport of a fatty acid is involved in regulation of the NCXSQ1 exchanger, providing a novel insight into the mechanism of its regulation. In order to identify the biologically active ligand, additional high-resolution mass-spectrometric studies of the ligands bound to ReP1-NCXSQ were performed after incubation with squid nerve vesicles both with and without MgATP. These studies clearly identified palmitic acid as the

  13. Statistics of Extremes

    KAUST Repository

    Davison, Anthony C.

    2015-04-10

    Statistics of extremes concerns inference for rare events. Often the events have never yet been observed, and their probabilities must therefore be estimated by extrapolation of tail models fitted to available data. Because data concerning the event of interest may be very limited, efficient methods of inference play an important role. This article reviews this domain, emphasizing current research topics. We first sketch the classical theory of extremes for maxima and threshold exceedances of stationary series. We then review multivariate theory, distinguishing asymptotic independence and dependence models, followed by a description of models for spatial and spatiotemporal extreme events. Finally, we discuss inference and describe two applications. Animations illustrate some of the main ideas. © 2015 by Annual Reviews. All rights reserved.

  14. Statistical Interior Tomography

    Science.gov (United States)

    Xu, Qiong; Wang, Ge; Sieren, Jered; Hoffman, Eric A.

    2011-01-01

    This paper presents a statistical interior tomography (SIT) approach making use of compressed sensing (CS) theory. With the projection data modeled by the Poisson distribution, an objective function with a total variation (TV) regularization term is formulated in the maximization of a posteriori (MAP) framework to solve the interior problem. An alternating minimization method is used to optimize the objective function with an initial image from the direct inversion of the truncated Hilbert transform. The proposed SIT approach is extensively evaluated with both numerical and real datasets. The results demonstrate that SIT is robust with respect to data noise and down-sampling, and has better resolution and less bias than its deterministic counterpart in the case of low count data. PMID:21233044

  15. Statistical physics ""Beyond equilibrium

    Energy Technology Data Exchange (ETDEWEB)

    Ecke, Robert E [Los Alamos National Laboratory

    2009-01-01

    The scientific challenges of the 21st century will increasingly involve competing interactions, geometric frustration, spatial and temporal intrinsic inhomogeneity, nanoscale structures, and interactions spanning many scales. We will focus on a broad class of emerging problems that will require new tools in non-equilibrium statistical physics and that will find application in new material functionality, in predicting complex spatial dynamics, and in understanding novel states of matter. Our work will encompass materials under extreme conditions involving elastic/plastic deformation, competing interactions, intrinsic inhomogeneity, frustration in condensed matter systems, scaling phenomena in disordered materials from glasses to granular matter, quantum chemistry applied to nano-scale materials, soft-matter materials, and spatio-temporal properties of both ordinary and complex fluids.

  16. Applied multivariate statistical analysis

    CERN Document Server

    Härdle, Wolfgang Karl

    2015-01-01

    Focusing on high-dimensional applications, this 4th edition presents the tools and concepts used in multivariate data analysis in a style that is also accessible for non-mathematicians and practitioners.  It surveys the basic principles and emphasizes both exploratory and inferential statistics; a new chapter on Variable Selection (Lasso, SCAD and Elastic Net) has also been added.  All chapters include practical exercises that highlight applications in different multivariate data analysis fields: in quantitative financial studies, where the joint dynamics of assets are observed; in medicine, where recorded observations of subjects in different locations form the basis for reliable diagnoses and medication; and in quantitative marketing, where consumers’ preferences are collected in order to construct models of consumer behavior.  All of these examples involve high to ultra-high dimensions and represent a number of major fields in big data analysis. The fourth edition of this book on Applied Multivariate ...

  17. Statistical physics of vaccination

    Science.gov (United States)

    Wang, Zhen; Bauch, Chris T.; Bhattacharyya, Samit; d'Onofrio, Alberto; Manfredi, Piero; Perc, Matjaž; Perra, Nicola; Salathé, Marcel; Zhao, Dawei

    2016-12-01

    Historically, infectious diseases caused considerable damage to human societies, and they continue to do so today. To help reduce their impact, mathematical models of disease transmission have been studied to help understand disease dynamics and inform prevention strategies. Vaccination-one of the most important preventive measures of modern times-is of great interest both theoretically and empirically. And in contrast to traditional approaches, recent research increasingly explores the pivotal implications of individual behavior and heterogeneous contact patterns in populations. Our report reviews the developmental arc of theoretical epidemiology with emphasis on vaccination, as it led from classical models assuming homogeneously mixing (mean-field) populations and ignoring human behavior, to recent models that account for behavioral feedback and/or population spatial/social structure. Many of the methods used originated in statistical physics, such as lattice and network models, and their associated analytical frameworks. Similarly, the feedback loop between vaccinating behavior and disease propagation forms a coupled nonlinear system with analogs in physics. We also review the new paradigm of digital epidemiology, wherein sources of digital data such as online social media are mined for high-resolution information on epidemiologically relevant individual behavior. Armed with the tools and concepts of statistical physics, and further assisted by new sources of digital data, models that capture nonlinear interactions between behavior and disease dynamics offer a novel way of modeling real-world phenomena, and can help improve health outcomes. We conclude the review by discussing open problems in the field and promising directions for future research.

  18. Sr. Sidão Manoel Inácio e a conquista da cidadania: o campesinato negro do Morro Alto e a República que foi

    Directory of Open Access Journals (Sweden)

    Rodrigo de Azevedo Weimer

    2015-06-01

    Full Text Available O presente artigo tem o objetivo de analisar as possibilidades de conquista de direitos cidadãos por parte do campesinato negro do Rio Grande do Sul durante a Primeira República, tomando o litoral norte do estado como locus de observação. Contesto, ou ao menos busco relativizar, a historiografia que enfatiza as limitações e obstáculos desse segmento populacional, oriundo da escravidão, para atingir tais prerrogativas. Procuro demonstrar os esforços e eventuais êxitos no alcance desses objetivos por meio de três grandes questões: o pagamento regular de impostos, o acesso à polícia e à justiça e a atuação militar.

  19. O Deus do progresso: a difusão do cientificismo no movimento operário gaúcho da I República

    Directory of Open Access Journals (Sweden)

    Benito Bisso Schmidt

    2001-01-01

    Full Text Available O objetivo do artigo é examinar a difusão de teorias cientificistas no movimento operário gaúcho no período da I República, tais como o positivismo, o darwinismo, a antropologia criminal, o espiritismo kardecista, etc.; bem como os canais de difusão de tais idéias e suas repercussões políticas, sobretudo a conformação de um "estilo autoritário" na condução das lutas operárias.This article aims at examining the diffusion of scientism theories in the gaúcho working movement in the 1st Republic, such as darwinism, criminal anthropology, the kardecist spiritism etc.; as well as the channels of diffusion of such ideas and its political repercution, above all else the conformation of an "authoritarian style" in the conduction of the working struggle.

  20. Las múltiples acepciones del término “historia” durante la Primera República en Nueva Granada, 1809-1815

    Directory of Open Access Journals (Sweden)

    Rodrigo de J. García Estrada

    2016-11-01

    Full Text Available El artículo explora las varias connotaciones que las élites criollas dieron al término “historia” durante la Primera República de la Nueva Granada, entre 1809 y 1815. La investigación recupera evidencia principalmente de dos tipos de usos de la voz historia. En una se muestra una concepción de la historia procedente de la perspectiva magistra vitae. En la otra, en cambio, se presenta una inuencia de una noción más moderna sobre la concepción del paso del tiempo. Los artículos escritos por Antonio Nariño, por ejemplo, ilustran un uso que se inscribe en este segundo caso.

  1. La República, la Guerra Civil Española y su impacto en la colectividad española de Valparaíso

    Directory of Open Access Journals (Sweden)

    Baldomero Estrada Turra

    2013-07-01

    Full Text Available Se analiza la evolución que tiene la colectividad española de Valparaíso durante la década de 1930 cuando España se ve afectada por la instauracion de la República y luego por la Guerra Civil. La ruptura que afectó a la comunidad española, como efecto de los acontecimientos de España, fue de una profundidad mayor que en otras ciudades del país y marcó su desarrollo institucional y comunitario por muchos años. Solo el paso de los años y los cambios generacionales permitieron superar las heridas del pasado.

  2. Sobre os meios e modos de fazer jornalismo na Primeira República: Lima Barreto entre a história e a ficção

    Directory of Open Access Journals (Sweden)

    Denilson Botelho

    2013-06-01

    Full Text Available Este artigo consiste na análise de um conto de Lima Barreto (1881-1922, intitulado “O jornalista”, publicado na revista Souza Cruz, em 1921, a partir do qual se discute e examina os meios e modos de fazer jornalismo na Primeira República. Tomando a literatura como fonte e como um tipo de documento, investiga-se o significado dessa publicação, bem como sua relação com outros textos do autor, a fim de perceber o quanto são capazes de revelar sobre as lutas travadas no universo da imprensa. Trata-se de resultados parciais de pesquisa desenvolvida no campo da história social da cultura, tendo como referenciais teóricos as contribuições de E. P. Thompson e Raymond Williams.

  3. Resumen de tesis. La Embriología en España durante la II República y el Franquismo (1931-1975)

    OpenAIRE

    Velasco Morgado, Raúl

    2013-01-01

    [Es]El presente trabajo analiza la Embriología en España durante los períodos de la II República y el Franquismo (1931-1975). Partiendo del método biográfico clásico, pero con un análisis que abarca la historia de las ideas, de la historia de las instituciones, la prosopografía y la historia de la ciencia más pura, se ha logrado reconstruir la evolución de la ciencia embriológica durante estos dos períodos políticos tan diferentes de la historia de nuestro país. El primer capítulo, tras ...

  4. Educação escolar na primeira república: memória, história e perspectivas de pesquisa

    Directory of Open Access Journals (Sweden)

    Alessandra Frota Martinez de Schueler

    2009-01-01

    Full Text Available O presente artigo desenvolve uma reflexão sobre a educação escolar, enfocando os debates, projetos e iniciativas voltadas para a disseminação da escola primária, no período da Primeira República (1889 a 1930, e problematizando a produção historiográfica sobre a educação republicana. Pretende-se contribuir para a abertura de um novo espectro de perguntas e problemas aos pesquisadores que se preocupam com a constituição da cultura escolar moderna e com os processos de socialização, transmissão, circulação, criação, apropriação e re (invenção culturais a partir da escola.

  5. Aproximación a ciertas nociones de historicidad en la prensa colombiana durante la Independencia e inicios de la República en Colombia (1810-1827

    Directory of Open Access Journals (Sweden)

    Rodgrigo de J. García Estrada

    2017-01-01

    Full Text Available Mediante un estudio sistemático de la prensa publicada en distintas ciudades de la actual Colombia durante la Independencia y los primeros años de la república de Colombia (llamada por los historiadores Gran Colombia, para no confundirla con la actual se analiza el contenido de los conceptos utilizados por los colaboradores y editores de los periódicos tratando de entender la semántica de nociones relacionadas con la historicidad, entre otros: historia, devenir, tiempo, permanencia y cambio; pasado, presente y futuro. Se muestran las evidencias de temporalidad propias del proceso revolucionario a partir de 1810, analizando la aceleración de los acontecimientos y su frecuencia, que dificultaba a los ciudadanos su registro y discernimiento.

  6. Review of inputs provided to Jason Associates Corporation in support of RWEV-REP-001, the Analysis of Postclosure Groundwater Impacts report.

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Charles R.; Weck, Philippe F.; Vaughn, Palmer; Arnold, Bill Walter

    2014-04-01

    Report RWEV-REP-001, Analysis of Postclosure Groundwater Impacts for a Geologic Repository for the Disposal of Spent Nuclear Fuel and High Level Radioactive Waste at Yucca Mountain, Nye County, Nevada was issued by the DOE in 2009 and is currently being updated. Sandia National Laboratories (SNL) provided support for the original document, performing calculations and extracting data from the Yucca Mountain Performance Assessment Model that were used as inputs to the contaminant transport and dose calculations by Jason Associates Corporation, the primary developers of the DOE report. The inputs from SNL were documented in LSA-AR-037, Inputs to Jason Associates Corporation in Support of the Postclosure Repository Supplemental Environmental Impact Statement. To support the updating of the original Groundwater Impacts document, SNL has reviewed the inputs provided in LSA-AR-037 to verify that they are current and appropriate for use. The results of that assessment are documented here.

  7. ¿Se volverá a equivocar el Banco de la República?. Dejen flotar la tasa de cambio

    Directory of Open Access Journals (Sweden)

    Alberto Gómez Mejía

    2007-01-01

    Full Text Available El Banco de la República viene practicando actualmente una política de tasa de cambio orientada a propiciar una devaluación del peso contrariando la tendencia del mercado que propicia su revaluación. Esto es el resultado de una recuperación económica cimentada en la estabilidad política, fortaleza del sector externo, inversión extranjera, precios favorables de las materias primas en los mercados internacionales y el papel creciente de las remesas. Se teme que el banco central vuelva a irrespetar el mercado tal como lo hizo durante el período 1994-1999 durante la vigencia de la banda cambiaria, cuando desperdició recursos y tiempo tratando de defender una tasa y un sistema que finalmente tuvo que abandonar al darse cuenta de la imposibilidad de conseguir los objetivos propuestos.

  8. Potencialidades del turismo ornitológico en El Caribe. Un análisis de República Dominicana./The challenges of tourism in the context of sustainability: the contributions of community-based tourism

    National Research Council Canada - National Science Library

    Francisco Orgaz Agüera; Tomás López Guzmán

    2015-01-01

      El turismo de sol y playa, en resorts "todo incluido", es la principal tipología turística de República Dominicana. Pero el turista busca nuevas experiencias en contacto con la naturaleza y la cultura local...

  9. De la ebullición a la contrarrevolución. Los significados del orden público en los libros de los gobernantes de la Segunda República Española, 1931-1936

    OpenAIRE

    Vaquero Martínez, Sergio

    2016-01-01

    Este artículo analiza los significados del orden público atribuidos por los gobernantes de la Segunda República española, en el marco de la cultura política republicana, mediante el estudio de sus memorias, diarios y libros. Para ampliar la compre

  10. "El mismo amor, la misma fe, las mismas lágrimas": iniciativas eclesiales en Ecuador sobre el culto a la Virgen del Quinche en defensa de una República del Sagrado Corazón (1883-1889)

    National Research Council Canada - National Science Library

    Luis Esteban Vizuete Marcillo

    2017-01-01

    ... de una República del Sagrado Corazón. El artículo analiza el caso de la Virgen del Quinche, culto colonial y de gran convocatoria, y el proceso de revalorización y reinterpretación de su historia. Este también experimentó...

  11. Influencia del campo magnético sobre el crecimiento de microorganismos patógenos ambientales aislados en el Archivo Nacional de la República de Cuba

    Directory of Open Access Journals (Sweden)

    Matilde Anaya

    2015-09-01

    Conclusión. Se concluyó que el campo magnético aplicado tuvo un efecto estimulante sobre los microorganismos estudiados, lo cual potencia el riesgo para la salud del personal y los visitantes del Archivo Nacional de la República de Cuba.

  12. Identification of CTX-M15-, SHV-28-producing Klebsiella pneumoniae ST15 as an epidemic clone in the Copenhagen area using a semi-automated Rep-PCR typing assay

    DEFF Research Database (Denmark)

    Nielsen, J B; Skov, M N; Jørgensen, R L

    2011-01-01

    Rapid molecular typing methods can be a valuable aid in the investigation of suspected outbreaks. We used a semi-automated repetitive sequence-based polymerase chain reaction (Rep-PCR) typing assay and pulsed field gel electrophoresis (PFGE) to investigate the relationship between local Klebsiella...

  13. Las relaciones culturales de España en tiempo de crisis: de la II República a la Guerra Mundial

    Directory of Open Access Journals (Sweden)

    Lorenzo Delgado Gómez-Escalonilla

    1994-01-01

    Full Text Available En los primeros meses de 1936 el personal de la Junta de Relaciones Culturales preparaba la memoria correspondiente al año anterior. Se daba continuidad con ella a la difusión de las actividades del organismo, comenzada tras el establecimiento de la II República, y que contaba ya con las publicaciones relativas a los años 1931-1933 y 1934. Esa preocupación por divulgar los resultados de su labor era una muestra más del dinamismo que había adquirido la Junta de Relaciones Culturales después de la reforma que experimentó en 1931. También recordaba a la actuación de la Junta para Ampliación de Estudios, que editaba sistemáticamente las memorias de sus actividades para dejar constancia pública del trabajo realizado. La analogía a este respecto no era casual. Con la república los intelectuales reformistas procedentes de la Institución Libre de Enseñanza, que tiempo atrás inspiraron la creación de la Junta para Ampliación de Estudios, habían recuperado el predicamento sobre la planificación de la política cultural con el extranjero. Pero la memoria de la Junta del año 1935 nunca llegó a aparecer. La guerra civil se cruzó en el camino de quienes la redactaban.

  14. Disputas políticas e reação centralizadora em Goiás na Primeira República – 1890 - 1905

    Directory of Open Access Journals (Sweden)

    Eliane

    2012-07-01

    Full Text Available A proclamação da República, em 1889, colocou em pauta, assim como a Independência em 1822 o havia feito, a necessidade de organização de uma nova estrutura jurídico-política para a nação brasileira. Sob a égide do federalismo, instituiu-se no âmbito da Justiça o sistema que a dividiu em Justiça Federal e Estadual. A legislação que consolidou essa nova organização, particularmente o Código Penal de 1890, recebeu, no entanto, inúmeras críticas por parte dos adeptos da Escola Positiva de Direito Penal. Para esses críticos, o novo Código já nascera ultrapassado perante as teorias jurídico-penais da época, bem como das transformações históricas pelas quais passara o país nas últimas décadas do Império. A Primeira República foi marcada, assim, pela tensão entre uma legislação de orientação liberal clássica e propostas de reformas institucionais e sociais, oriundas dos adeptos da nova criminologia. Nesse sentido, buscamos neste texto analisar a legislação goiana que disciplinou, no período de 1890 a 1905, a organização e o funcionamento da Justiça no estado. Interessou-nos, em particular, compreender como foram tratadas as questões referentes à organização da Justiça estadual e à aplicação do direito processual. Concomitantemente, procuramos discutir o discurso do Executivo estadual, que buscou justificar as modificações ocorridas na mesma.

  15. A Constituição da República de 1988 e a hierarquia dos Tratados de Direitos Humanos no ordenamento jurídico brasileiro

    Directory of Open Access Journals (Sweden)

    Julio Cesar de Aguiar

    2016-11-01

    Full Text Available O presente artigo busca analisar o modo pelo qual o Direito brasileiro – em especial a Constituição da República de 1988 – se relaciona com os instrumentos internacionais de proteção aos direitos humanos, bem como abordar a problemática da hierarquização “diferenciada” e a contribuição ofertada por estes instrumentos para o aperfeiçoamento do ordenamento jurídico interno, em um contexto histórico do período pós-Segunda Guerra Mundial, quando a comunidade internacional passou não só a reconhecer, mas também a dar mais importância à proteção aos direitos humanos, os quais são questões de legítimos interesses e preocupação internacional. Por fim, apesar de prevalecer o entendimento - da jurisprudência do STF - de que os acordos que versem sobre direitos humanos, se aprovados no Congresso Nacional com quórum e procedimento de Emenda Constitucional, têm a mesma hierarquia da Constituição, caso contrário, adquirem status superior às leis complementares e ordinária e inferior à Constituição, status de supra legalidade, há ainda, a discussão para saber qual o verdadeiro sentido do parágrafo 3º do Art. 5º Constituição da República de 1988.

  16. La república de los sueños o la conformación de una nación de exiliados

    Directory of Open Access Journals (Sweden)

    Juan David González Betancur

    2010-06-01

    Full Text Available This article is part of the thesis "Una identidad para los apátridas", which the author presented to get his Master’s Degree in Literature. It explores the topic of the Brazilian national identity in relationship with exile in Nélida Piñon’s historical novel La república de los sueños. This identity question issue, for which answers have been found in the concept of nation in Latin American literature, follows this clue but focuses on a contemporary way of understanding it. Literature fiction with historical speech answers for an idea of nation that breaks traditional categories.//Este artículo hace parte de la tesis “Una identidad para los apátridas", con la que su autor obtuvo el título de Magister en Literatura. El texto explora el tema de la identidad nacional brasilera en relación con el exilio, a partir de la novela histórica de Nélida Piñon, La república de los sueños. Esa pregunta por la identidad, que en la literatura latinoamericana ha hallado respuestas en el concepto de nación, sigue estas pistas, pero da un giro hacia una manera contemporánea de entender dicha cuestión. La ficción literaria se mezcla con el discurso histórico para dar respuesta a una idea de nación que rompe con los cánones tradicionales.

  17. Waste statistics 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-04-07

    The 2004 reporting to the ISAG comprises 394 plants owned by 256 enterprises. In 2003, reports covered 403 plants owned by 273 enterprises. Waste generation in 2004 is compared to targets for 2008 in the government's Waste Strategy 2005-2008. The following summarises waste generation in 2004: 1) In 2004, total reported waste arisings amounted to 13,359,000 tonnes, which is 745,000 tonnes, or 6 per cent, more than in 2003. 2) If amounts of residues from coal-fired power plants are excluded from statistics, waste arisings in 2004 were 12,179,000 tonnes, which is a 9 per cent increase from 2003. 3) If amounts of residues from coal-fired power plants and waste from the building and construction sector are excluded from statistics, total waste generation in 2004 amounted to 7,684,000 tonnes, which is 328,000 tonnes, or 4 per cent, more than in 2002. In other words, there has been an increase in total waste arisings, if residues and waste from building and construction are excluded. Waste from the building and construction sector is more sensitive to economic change than most other waste. 4) The total rate of recycling was 65 per cent. The 2008 target for recycling is 65 per cent. The rate of recycling in 2003 was also 65 per cent. 5) The total amount of waste led to incineration amounted to 26 per cent, plus an additional 1 per cent left in temporary storage to be incinerated at a later time. The 2008 target for incineration is 26 per cent. These are the same percentage figures as applied to incineration and storage in 2003. 6) The total amount of waste led to landfills amounted to 8 per cent, which is one percentage point better than the overall landfill target of a maximum of 9 per cent landfilling in 2008. Also in 2003, 8 per cent of the waste was landfilled. 7) The targets for treatment of waste from individual sectors are still not being met: too little waste from households and the service sector is being recycled, and too much waste from industry is being

  18. Waste statistics 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The 2003 reporting to the ISAG comprises 403 plants owned by 273 enterprises. In 2002, reports covered 407 plants owned by 296 enterprises. Waste generation in 2003 is compared to targets from 2008 in the government's Waste Strategy 2005-2008. The following can be said to summarise waste generation in 2003: 1) In 2003, total reported waste arisings amounted to 12,835,000 tonnes, which is 270,000 tonnes, or 2 per cent, less than in 2002. 2) If amounts of residues from coal-fired power plants are excluded from statistics, waste arisings in 2003 were 11,597,000 tonnes, which is a 2 per cent increase from 2002. 3) If amounts of residues from coal-fired power plants and waste from the building and construction sector are excluded from statistics, total waste generation in 2003 amounted to 7,814,000 tonnes, which is 19,000 tonnes, or 1 per cent, less than in 2002. In other words, there has been a fall in total waste arisings, if residues and waste from building and construction are excluded. 4) The overall rate of recycling amounted to 66 per cent, which is one percentage point above the overall recycling target of 65 per cent for 2008. In 2002 the total rate of recycling was 64 per cent. 5) The total amount of waste led to incineration amounted to 26 per cent, plus an additional 1 per cent left in temporary storage to be incinerated at a later time. The 2008 target for incineration is 26 per cent. These are the same percentage figures as applied to incineration and storage in 2002. 6) The total amount of waste led to landfills amounted to 8 per cent, which is one percentage point below the overall landfill target of a maximum of 9 per cent landfilling in 2008. In 2002, 9 per cent was led to landfill. 7) The targets for treatment of waste from individual sectors are still not being met: too little waste from households and the service sector is being recycled, and too much waste from industry is being led to landfill. (au)

  19. German cancer statistics 2004

    Directory of Open Access Journals (Sweden)

    Ziese Thomas

    2010-02-01

    Full Text Available Abstract Background For years the Robert Koch Institute (RKI has been annually pooling and reviewing the data from the German population-based cancer registries and evaluating them together with the cause-of-death statistics provided by the statistical offices. Traditionally, the RKI periodically estimates the number of new cancer cases in Germany on the basis of the available data from the regional cancer registries in which registration is complete; this figure, in turn, forms the basis for further important indicators. Methods This article gives a brief overview of current indicators - such as incidence, prevalence, mortality, survival rates - on the most common types of cancer, as well as important ratios on the risks of developing and dying of cancer in Germany. Results According to the latest estimate, there were a total of 436,500 new cancer cases in Germany in 2004. The most common cancer in men is prostate cancer with over 58,000 new cases per annum, followed by colorectal and lung cancer. In women, breast cancer remains the most common cancer with an estimated 57,000 new cases every year, also followed by colorectal cancer. These and further findings on selected cancer sites can be found in the current brochure on "Cancer in Germany", which is regularly published by the RKI together with the Association of Population-based Cancer Registries in Germany (GEKID. In addition, the RKI made cancer-prevalence estimates and calculated current morbidity and mortality risks at the federal level for the first time. According to these figures, the 5-year partial prevalence - i.e. the total number of cancer patients diagnosed over the past five years who are currently still living - exceeds 600,000 in men; the figure is about the same among women. Here, too, the most common cancers are prostate cancer in men and breast cancer in women. The lifetime risk of developing cancer, which is more related to the individual, is estimated to be higher among

  20. Statistics with JMP graphs, descriptive statistics and probability

    CERN Document Server

    Goos, Peter

    2015-01-01

    Peter Goos, Department of Statistics, University ofLeuven, Faculty of Bio-Science Engineering and University ofAntwerp, Faculty of Applied Economics, BelgiumDavid Meintrup, Department of Mathematics and Statistics,University of Applied Sciences Ingolstadt, Faculty of MechanicalEngineering, GermanyThorough presentation of introductory statistics and probabilitytheory, with numerous examples and applications using JMPDescriptive Statistics and Probability provides anaccessible and thorough overview of the most important descriptivestatistics for nominal, ordinal and quantitative data withpartic