WorldWideScience

Sample records for psd science handouts

  1. The Effects of Inquiry Training Assist Media of Handout and Attitude Scientific Towards Science Process Skills in Physics Students

    OpenAIRE

    Sakdiah, Halimatus; Sahyar ,

    2014-01-01

    The purpose of this research has described difference: (1) skill of student science process between inquiry training assist media of handout and direct instruction, (2) skill of student science process between student possess attitude scientific upon and under of mean, and (3) interaction of inquiry training assist media handout and direct instruction with attitude scientific increase skill of student science process. Type of this research is experiment quasi, use student of senior high schoo...

  2. THE EFFECTS OF INQUIRY TRAINING ASSIST MEDIA OF HANDOUT AND ATTITUDE SCIENTIFIC TOWARDS SCIENCE PROCESS SKILLS IN PHYSICS STUDENTS

    Directory of Open Access Journals (Sweden)

    Halimatus Sakdiah

    2014-12-01

    Full Text Available The purpose of this research has described difference: (1 skill of student science process between inquiry training assist media of handout and direct instruction, (2 skill of student science process between student possess attitude scientific upon and under of mean, and (3 interaction of inquiry training assist media handout and direct instruction with attitude scientific increase skill of student science process. Type of this research is experiment quasi, use student of senior high school Private sector of  Prayatna as population and chosen sample by cluster sampling random. The instrument used essay test base on skill of science process which have valid and reliable. Data be analysed by using ANAVA two ways. Result of research show that any difference of skill of student science process (1 between inquiry training assist media of handout and direct instruction, where inquiry training assist media of handout better then direct instruction, (2 between student possess attitude scientific upon and under of mean, where possess attitude scientific upon of mean better then student possess attitude scientific under of mean and (3 any interaction between inquiry training assist media of handout and direct instruction with attitude scientific increase skill of student science process, where interaction in class direct instruction better then inquiry training assist media of handout.

  3. Developing Statistical Physics Course Handout on Distribution Function Materials Based on Science, Technology, Engineering, and Mathematics

    Science.gov (United States)

    Riandry, M. A.; Ismet, I.; Akhsan, H.

    2017-09-01

    This study aims to produce a valid and practical statistical physics course handout on distribution function materials based on STEM. Rowntree development model is used to produce this handout. The model consists of three stages: planning, development and evaluation stages. In this study, the evaluation stage used Tessmer formative evaluation. It consists of 5 stages: self-evaluation, expert review, one-to-one evaluation, small group evaluation and field test stages. However, the handout is limited to be tested on validity and practicality aspects, so the field test stage is not implemented. The data collection technique used walkthroughs and questionnaires. Subjects of this study are students of 6th and 8th semester of academic year 2016/2017 Physics Education Study Program of Sriwijaya University. The average result of expert review is 87.31% (very valid category). One-to-one evaluation obtained the average result is 89.42%. The result of small group evaluation is 85.92%. From one-to-one and small group evaluation stages, averagestudent response to this handout is 87,67% (very practical category). Based on the results of the study, it can be concluded that the handout is valid and practical.

  4. Instructional Architect Teacher Professional Development Handouts

    OpenAIRE

    Recker, Mimi; Walker, Andrew; Robertshaw, M Brooke; Sellers, Linda; Leary, Heather M.

    2009-01-01

    Three handouts for the teacher professional development workshops on the Instructional Architect (IA). Starting spring 2009 the face-to-face workshop was changed to be three different days of learning about how to use the IA, inquiry based and problem based learning, evaluation of IA projects with a rubric, and creating IA projects.

  5. PSD Increment Consumption Guidance

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  6. PSD Increment Consumption Question

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  7. Remote Laser Diffraction PSD Analyzer

    Energy Technology Data Exchange (ETDEWEB)

    Batcheller, Thomas Aquinas; Huestis, Gary Michael; Bolton, Steven Michael

    2000-06-01

    Particle size distribution (PSD) analysis of radioactive slurry samples were obtained using a modified "off-the-shelf" classical laser light scattering particle size analyzer. A Horiba Instruments Inc. Model La-300 PSD analyzer, which has a 0.1 to 600 micron measurement range, was modified for remote application in a "hot cell" (gamma radiation) environment. The general details of the modifications to this analyzer are presented in this paper. This technology provides rapid and simple PSD analysis, especially down in the fine and microscopic particle size regime. Particle size analysis of these radioactive slurries down in this smaller range was not achievable - making this technology far superior than the traditional methods used previously. Remote deployment and utilization of this technology is in an exploratory stage. The risk of malfunction in this radiation environment is countered by gaining of this tremendously useful fundamental engineering data. Successful acquisition of this data, in conjunction with other characterization analyses, provides important information that can be used in the myriad of potential radioactive waste management alternatives.

  8. Impact of utilisation of uncompleted handouts on power point presentations (PPT in rural Indian medical institute

    Directory of Open Access Journals (Sweden)

    ROSHAN BHAISARE

    2016-07-01

    Full Text Available Introduction: Note taking while attending a PPT requires high activity of memory and writing process which ultimately leads to what is called “death by power point” referring to boredom and fatigue. To overcome this we planned to evaluate the impact of utilisation of uncompleted handouts given prior to PPT presentations. Methods: Final year MBBS students were divided in 2 batches, batch A and batch B. For a set of lectures one batch was provided with handouts before lecture while the other batch was given lectures only. Crossover was done to avoid bias, all the lectures being given by the same presenter. At the end of each lecture, a short questionnaire of 10 Multiple Choice Question (MCQ was provided to the students. Mean scores were calculated for lectures with handouts and without handouts. Results: For a set of lectures, when batch A was provided with handouts, the mean score was 28.2; for batch B to which no handouts were given the mean score was 23.4. Similarly, for batch B when provided with handouts the mean score was 29.1, for batch A which was not provided with handouts the mean score was 24. There was an average increase of 4.2 marks. Actual gain when handouts were provided was 1.2 marks per lecture. It was more for the batch comprising of repeater students as compared to the batch of fresher students. Increase in attendance was also noted. Conclusion: Providing uncompleted handouts before a didactic lecture definitely results in increase in knowledge gain; repeater students benefit more with uncompleted handouts.

  9. PSD Determination, Portland Cement Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  10. PENGEMBANGAN HANDOUT DINAMIKA POPULASI HEWAN BERBASIS POTENSI LOKAL DENGAN SUMBER BELAJAR DI DANAU SINGKARAK SUMATERA BARAT

    Directory of Open Access Journals (Sweden)

    Finga Fitri Amanda

    2016-11-01

    Full Text Available This research aims to develop teaching materials in the form of handout that equipped with RPS, SAP, and assessment instruments consist of psychomotor and attitude. This handout based on local potential in West Sumatra as supporting animal ecology course with a discussion of the dynamics of animal populations, especially in fish endemic named bilih fish. This research is a development research that reference to the model of Borg and Gall (1983, includes 10 stages, namely (1 information collection, (2 planning, (3 early product development, (4 introduction field testing, (5 product revision , (6 the main field trials, (7 the revised operational products, (8 operational field trials, (9 the final revision product, and (10 the dissemination and implementation. Development handout only done until the fifth stage. Validity of the product development assessment by expert learning validator, subject experts, and two expert field practitioners. Percentage validation results handout respectively, are 97.9%, 92.7%, 94.3%. The results of introduction field testing that conducted by 12 biology students of STKIP PGRI West Sumatra that has been studying the material of animal population dynamics. The results of introduction field testing is 88.8%. Percentage of validation results RPS, SAP, and Instruments by expert lecturers respectively 97.8%, 93.8% and 96.2%. The average percentage of product development and validation of introduction field testing were categorized excellent. Penelitian ini bertujuan untuk mengembangkan bahan ajar berupa handout yang dilengkapi dengan RPS, SAP, dan instrumen penilaian psikomotorik dan penilaian sikap. Handout ini berbasis potensi lokal di Sumatera Barat sebagai penunjang matakuliah Ekologi Hewan dengan bahasan tentang dinamika populasi hewan khususnya pada ikan endemik, yaitu ikan bilih. Penelitian ini merupakan penelitian pengembangan dengan mengacu pada model Borg & Gall (1983 meliputi 10 tahapan, yaitu (1 pengumpulan

  11. Influence of Presentation Handout Completeness on Student Learning in a Physical Therapy Curriculum

    Science.gov (United States)

    Nelson-Wong, Erika; Eigsti, Heidi; Hammerich, Amy; Ellison, Nicole

    2013-01-01

    Students and faculty have disparate opinions on how complete lecture materials should be to optimize learning. The purpose of this study was to investigate the influence of lecture handout completeness and content area on Doctor of Physical Therapy student recall/retention in foundation level courses. These findings suggest there may not be a best…

  12. Structure of the first PDZ domain of human PSD-93

    DEFF Research Database (Denmark)

    Fiorentini, Monica; Nielsen, Ann Kallehauge; Kristensen, Ole

    2009-01-01

    the PDZ1-PDZ2 linker region at the extreme C-terminus of PDZ1, implying that the oligomerization that is observed is not of biological significance in full-length PSD-93. Comparison of the structures of the binding cleft of PSD-93 PDZ1 with the previously reported structures of PSD-93 PDZ2 and PDZ3...

  13. Some upper and lower bounds on PSD-rank

    NARCIS (Netherlands)

    T. J. Lee (Troy); Z. Wei (Zhaohui); R. M. de Wolf (Ronald)

    2014-01-01

    textabstractPositive semidefinite rank (PSD-rank) is a relatively new quantity with applications to combinatorial optimization and communication complexity. We first study several basic properties of PSD-rank, and then develop new techniques for showing lower bounds on the PSD-rank. All of these

  14. Some upper and lower bounds on PSD-rank

    NARCIS (Netherlands)

    Lee, T.; Wei, Z.; de Wolf, R.

    Positive semidefinite rank (PSD-rank) is a relatively new complexity measure on matrices, with applications to combinatorial optimization and communication complexity. We first study several basic properties of PSD-rank, and then develop new techniques for showing lower bounds on the PSD-rank. All

  15. Hand-out: SFOE research conference on traffic technology and accumulators; Handout BFE-Forschungstagung Technologiebereich Verkehr Technologiebereich Akkumulatoren

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This comprehensive collection contains presentation slides presented at a research conference organised by the Swiss Federal Office of Energy (SFOE) at the Federal Institute of Science and Technology in Zurich in February 2004. Apart from two presentations on the future of the 'SwissEnergy' programme and research in the EU, fifteen further presentations are included. These cover the 'Cleaner Drive' project, the influence of lightweight electric vehicles on mobility behaviour, the advantages of 'EcoDrive' in the year 2010, results of a study on 'park-and-ride' facilities, the CO{sub 2}-effect, innovation, the possibilities offered by S-Cap capacitors and 'Sun Fuels'. Further contributions include the 'Downhill Coaster', weather-protection for bicycles, natural-gas fuelled buses, the operation of an Otto-motor using a petrol / natural gas / reformer gas mix, usage and optimisation of the 'Zebra' battery, innovative vehicles for the 'Novatlantis'-pilot region in Basle and a contribution on climate protection in the aviation area.

  16. Comprehension of the education handout and health literacy of pacemaker users.

    Science.gov (United States)

    Santos, Jackelline Evellin Moreira Dos; Brasil, Virginia Visconde; Moraes, Katarinne Lima; Cordeiro, Jacqueline Andréia Bernardes Leão; Oliveira, Gabriela Ferreira de; Bernardes, Carla de Paula; Bueno, Bárbara Ribeiro Miquelin; Boaventura, Rafaela Peres; Gonçalves, Fernanda Alves Ferreira; Oliveira, Lizete Malagoni de Almeida Cavalcante; Barbosa, Maria Alves; Silva, Antonio Márcio Teodoro Cordeiro

    2017-01-01

    To verify the comprehension of the education handout and the level of Functional Health Literacy of individuals with cardiac pacemaker (PM) and whether there is correlation between the comprehension and Functional Health Literacy (FHL). Cross-sectional study with 63 individuals with PM who answered to comprehension tests of the handout, literacy assessment (SAHLPA-50) and cognition (MMSE). Measurements of dispersion, Pearson correlation and multiple linear regression were calculated. Most women, study time ≤ 9 years, 66.21 (average age) presented no cognitive changes. An adequate literacy level was evidenced in 50.8% individuals with PM and satisfactory comprehension of the handout. No correlation was identified between FHL, handout comprehension, age, years of study and cognition. The handout comprehension assessed by individuals with appropriate FHL indicated that it can be a printed material suitable for use, aiming to improve care process and knowledge of individuals with PM. Verificar a legibilidade de prospecto facilitador da aprendizagem e o nível de Letramento Funcional em Saúde de indivíduos com marcapasso cardíaco (MP) e se há correlação entre a legibilidade e Letramento Funcional em Saúde (LFS). Estudo transversal com 63 indivíduos com MP, que responderam testes de legibilidade do prospecto, de avaliação do letramento (SAHLPA-50) e cognição (MEEM). Foram calculadas medidas de dispersão, correlação de Pearson e regressão linear múltipla. Maioria mulheres, tempo de estudo ≤ 9 anos, idade média de 66,21 anos, sem alteração cognitiva. Evidenciado nível adequado de letramento em 50,8% dos indivíduos com MP e legibilidade satisfatória do prospecto. Não foi identificada correlação entre LFS, legibilidade do prospecto, idade, anos de estudo e cognição. A legibilidade do prospecto avaliada por indivíduos com adequado LFS indicou que pode ser um impresso educativo apropriado para uso, visando aprimorar o processo de cuidar e o

  17. PENGEMBANGAN HANDOUT BERBASIS KONTEKSTUAL PADA PELAJARAN BIOLOGI MATERI BIOTEKNOLOGI UNTUK SISWA KELAS XII SMK NEGERI 02 BATU

    Directory of Open Access Journals (Sweden)

    Fega Rahmayani

    2015-03-01

    Full Text Available The teaching learning activity in SMK is inappropriate with the purpose of teaching and learning in SMK, which the students are taught to be able to apply the materials in the real life. Teaching material is taken from the biology book of SMA that the content is theoretically, so the explanation on the material is unsuitable and not applicative that makes the student less in ability and skill for application in daily life. From the problem above, this research purpose on developing the contextual basic handout of the biological course in biotechnology material in SMK N 02 Batu.This research is developing research based on research and development by Sugiyono’s model that use a few developing steps, those are: (1 Potential and problem, (2 Collecting data, (3 Product design, (4 Validation design, (5 Design revision, (6 Try out the product, (7 Product revision. The data collecting methods is using validation from the expert of handout, material expert and try out to the study club. The technique of analyze data using quantitative and qualitative data. The result of quantitative data is the percentage of handout product value that classify in the handout quality and the result of qualitative data come from comment and advise of validator and try out in SMK.The result quality of the handout found that the developing contextual basic handout reach out the good quality after following the procedure of validation with percentage 80.90% and try out to the student that use the handout with percentage very good, 97.75% and get the positive respond from student with percentage 90.82%. From the whole of the contextual basic handout have a good quality and appropriate in use for teaching material of Biology in teaching learning process in SMK N 02 Batu.

  18. PSD Applicability: Industrial Scrap Processing Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  19. Baseline Value for PSD Increment Consumption

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  20. PSD Applicability Determination - Southwestern Public Service Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  1. PSD Determination - Consolidated Edison of New York

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  2. PSD Determination Cabot Corporation - Fuel Conversion

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  3. PSD Applicability Pulp and Paper Mill

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  4. Turbine Enhancements and PSD Applicability -- Holcomb Station

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  5. Posttranslational Modifications Regulate the Postsynaptic Localization of PSD-95.

    Science.gov (United States)

    Vallejo, Daniela; Codocedo, Juan F; Inestrosa, Nibaldo C

    2017-04-01

    The postsynaptic density (PSD) consists of a lattice-like array of interacting proteins that organizes and stabilizes synaptic receptors, ion channels, structural proteins, and signaling molecules required for normal synaptic transmission and synaptic function. The scaffolding and hub protein postsynaptic density protein-95 (PSD-95) is a major element of central chemical synapses and interacts with glutamate receptors, cell adhesion molecules, and cytoskeletal elements. In fact, PSD-95 can regulate basal synaptic stability as well as the activity-dependent structural plasticity of the PSD and, therefore, of the excitatory chemical synapse. Several studies have shown that PSD-95 is highly enriched at excitatory synapses and have identified multiple protein structural domains and protein-protein interactions that mediate PSD-95 function and trafficking to the postsynaptic region. PSD-95 is also a target of several signaling pathways that induce posttranslational modifications, including palmitoylation, phosphorylation, ubiquitination, nitrosylation, and neddylation; these modifications determine the synaptic stability and function of PSD-95 and thus regulate the fates of individual dendritic spines in the nervous system. In the present work, we review the posttranslational modifications that regulate the synaptic localization of PSD-95 and describe their functional consequences. We also explore the signaling pathways that induce such changes.

  6. Comparative effectiveness of videotape and handout mode of instructions for teaching exercises: skill retention in normal children

    Directory of Open Access Journals (Sweden)

    Gupta Garima

    2012-01-01

    Full Text Available Abstract Background Teaching of motor skills is fundamental to physical therapy practice. In order to optimize the benefits of these teaching and training efforts, various forms of patient education material are developed and handed out to patients. One very important fact has been overlooked. While comparative effectiveness of various modes of instruction has been studied in adults, attention has not been paid to the fact that learning capabilities of children are different from that of adults. The intent of the present study is to compare the effectiveness of video and handout mode of instructions specifically on children. Methods A total of 115 normal elementary-age children aged 10 to 12 years of age were studied. The children were randomized into two groups: A the video group, and B the handout group. The video group viewed the video for physical therapy exercises while the handout group was provided with paper handouts especially designed according to the readability of their age group. Results Statistical analysis using the student's't' test showed that subjects of both the video and handout groups exhibited equal overall performance accuracy. There was no significant difference between the groups both in acquisition and retention accuracy tests. Conclusion The findings of the present study suggest that if the readability and instructional principles applicable to different target age groups are strictly adhered to, then both video as well as handout modes of instructions result in similar feedback and memory recall in ten to twelve year-old children. Principles of readability related to the patient age are of utmost importance when designing the patient education material. These findings suggest that the less expensive handouts can be an effective instructional aid for teaching exercises to children with various neuromuscular, rheumatic, and orthopedics conditions and the most costly videotape techniques are not necessarily better.

  7. Comparative effectiveness of videotape and handout mode of instructions for teaching exercises: skill retention in normal children.

    Science.gov (United States)

    Gupta, Garima; Sehgal, Stuti

    2012-01-30

    Teaching of motor skills is fundamental to physical therapy practice. In order to optimize the benefits of these teaching and training efforts, various forms of patient education material are developed and handed out to patients. One very important fact has been overlooked. While comparative effectiveness of various modes of instruction has been studied in adults, attention has not been paid to the fact that learning capabilities of children are different from that of adults. The intent of the present study is to compare the effectiveness of video and handout mode of instructions specifically on children. A total of 115 normal elementary-age children aged 10 to 12 years of age were studied. The children were randomized into two groups: A) the video group, and B) the handout group. The video group viewed the video for physical therapy exercises while the handout group was provided with paper handouts especially designed according to the readability of their age group. Statistical analysis using the student's't' test showed that subjects of both the video and handout groups exhibited equal overall performance accuracy. There was no significant difference between the groups both in acquisition and retention accuracy tests. The findings of the present study suggest that if the readability and instructional principles applicable to different target age groups are strictly adhered to, then both video as well as handout modes of instructions result in similar feedback and memory recall in ten to twelve year-old children. Principles of readability related to the patient age are of utmost importance when designing the patient education material. These findings suggest that the less expensive handouts can be an effective instructional aid for teaching exercises to children with various neuromuscular, rheumatic, and orthopedics conditions and the most costly videotape techniques are not necessarily better.

  8. North Coast Unified Air Quality Management District: PSD Delegation Agreements

    Science.gov (United States)

    Agreements for Partial Delegation of the Federal Prevention of Significant Deterioration (PSD) Program Set Forth in 40 CPR 52.21 by the United States Environmental Protection Agency, Region 9 to the North Coast Unified Air Quality Management District.

  9. Psd1 Effects on Candida albicans Planktonic Cells and Biofilms

    Directory of Open Access Journals (Sweden)

    Sónia Gonçalves

    2017-06-01

    Full Text Available Candida albicans is an important human pathogen, causing opportunistic infections. The adhesion of planktonic cells to a substrate is the first step for biofilm development. The antimicrobial peptide (AMP Psd1 is a defensin isolated from Pisum sativum seeds. We tested the effects of this AMP on C. albicans biofilms and planktonic cells, comparing its activity with amphotericin B and fluconazole. Three C. albicans variants were studied, one of them a mutant deficient in glucosylceramide synthase, conferring resistance to Psd1 antifungal action. Atomic force microscopy (AFM was used to assess morphological and biomechanical changes on fungal cells. Surface alterations, with membrane disruption and leakage of cellular contents, were observed. Cytometry assays and confocal microscopy imaging showed that Psd1 causes cell death, in a time and concentration-dependent manner. These results demonstrate Psd1 pleiotropic action against a relevant fungal human pathogen, suggesting its use as natural antimycotic agent.

  10. Student Analysis of Handout Development based on Guided Discovery Method in Process Evaluation and Learning Outcomes of Biology

    Science.gov (United States)

    Nerita, S.; Maizeli, A.; Afza, A.

    2017-09-01

    Process Evaluation and Learning Outcomes of Biology subjects discusses the evaluation process in learning and application of designed and processed learning outcomes. Some problems found during this subject was the student difficult to understand the subject and the subject unavailability of learning resources that can guide and make students independent study. So, it necessary to develop a learning resource that can make active students to think and to make decisions with the guidance of the lecturer. The purpose of this study is to produce handout based on guided discovery method that match the needs of students. The research was done by using 4-D models and limited to define phase that is student requirement analysis. Data obtained from the questionnaire and analyzed descriptively. The results showed that the average requirement of students was 91,43%. Can be concluded that students need a handout based on guided discovery method in the learning process.

  11. Marshall Space Flight Center Propulsion Systems Department (PSD) KM Initiative

    Science.gov (United States)

    Caraccioli, Paul; Varnadoe, Tom; McCarter, Mike

    2006-01-01

    NASA Marshall Space Flight Center s Propulsion Systems Department (PSD) is four months into a fifteen month Knowledge Management (KM) initiative to support enhanced engineering decision making and analyses, faster resolution of anomalies (near-term) and effective, efficient knowledge infused engineering processes, reduced knowledge attrition, and reduced anomaly occurrences (long-term). The near-term objective of this initiative is developing a KM Pilot project, within the context of a 3-5 year KM strategy, to introduce and evaluate the use of KM within PSD. An internal NASA/MSFC PSD KM team was established early in project formulation to maintain a practitioner, user-centric focus throughout the conceptual development, planning and deployment of KM technologies and capabilities with in the PSD. The PSD internal team is supported by the University of Alabama's Aging Infrastructure Systems Center Of Excellence (AISCE), Intergraph Corporation, and The Knowledge Institute. The principle product of the initial four month effort has been strategic planning of PSD KM implementation by first determining the "as is" state of KM capabilities and developing, planning and documenting the roadmap to achieve the desired "to be" state. Activities undertaken to support the planning phase have included data gathering; cultural surveys, group work-sessions, interviews, documentation review, and independent research. Assessments and analyses have been performed including industry benchmarking, related local and Agency initiatives, specific tools and techniques used and strategies for leveraging existing resources, people and technology to achieve common KM goals. Key findings captured in the PSD KM Strategic Plan include the system vision, purpose, stakeholders, prioritized strategic objectives mapped to the top ten practitioner needs and analysis of current resource usage. Opportunities identified from research, analyses, cultural/KM surveys and practitioner interviews include

  12. A Comparison of PSD Enveloping Methods for Nonstationary Vibration

    Science.gov (United States)

    Irvine, Tom

    2015-01-01

    There is a need to derive a power spectral density (PSD) envelope for nonstationary acceleration time histories, including launch vehicle data, so that components can be designed and tested accordingly. This paper presents the results of the three methods for an actual flight accelerometer record. Guidelines are given for the application of each method to nonstationary data. The method can be extended to other scenarios, including transportation vibration.

  13. Prevention of Significant Deterioration (PSD) Emission Thresholds for Fountain Foundry

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  14. Memo on PSD Applicability Determination for an Ethanol Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  15. National Asphalt Pavement Association Questions and Answers on PSD

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. Request for Guidance on PSD Applicability Determinations for Boiler Emissions

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  17. Applicability of PSD to Pennsylvania Power and Light Auxiliary Boiler

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  18. Valero Hydrocarbons BACT Analysis, PSD-TX-746

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  19. USDA Forest Service, Rocky Mountain Region PSD Permit Completeness Determination

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  20. PSD Applicability - Public Service Electric and Gas Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  1. Applicability of EPA's PSD Regulations to Floating Seafood Processors

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  2. Applicability of PSD to the Consolidated Edison Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  3. Appeal Procedures for PSD Permits Under The Consolidated Permit Regulations

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  4. PSD Determination of Applicability - UMD Coal Gasification Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  5. Determining PSD Applicability Thresholds for Gas Turbine Based Facilities

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  6. Applicability of PSD to Carter Oil Company Pilot Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  7. Union Carbide Chemicals and Plastics Company, Inc PSD Applicability

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  8. VID22 is required for transcriptional activation of the PSD2 gene in the yeast Saccharomyces cerevisiae.

    Science.gov (United States)

    Miyata, Non; Miyoshi, Takuya; Yamaguchi, Takanori; Nakazono, Toshimitsu; Tani, Motohiro; Kuge, Osamu

    2015-12-15

    Phosphatidylethanolamine (PE) in the yeast Saccharomyces cerevisiae is synthesized through decarboxylation of phosphatidylserine (PS), catalysed by PS decarboxylase 1 (Psd1p) and 2 (Psd2p) and the cytidine 5'-diphosphate (CDP)-ethanolamine (CDP-Etn) pathway. PSD1 null (psd1Δ) and PSD2 null (psd2Δ) mutants are viable in a synthetic minimal medium, but a psdpsd2Δ double mutant exhibits Etn auxotrophy, which is incorporated into PE through the CDP-Etn pathway. We have previously shown that psd1Δ is synthetic lethal with deletion of VID22 (vid22Δ) [Kuroda et al. (2011) Mol. Microbiol. 80: , 248-265]. In the present study, we found that vid22Δ mutant exhibits Etn auxotrophy under PSD1-depressed conditions. Deletion of VID22 in wild-type and PSD1-depressed cells caused partial defects in PE formation through decarboxylation of PS. The enzyme activity of PS decarboxylase in an extract of vid22Δ cells was ∼70% of that in wild-type cells and similar to that in psd2Δ cells and the PS decarboxylase activity remaining in the PSD1-depressed cells became almost negligible with deletion of VID22. Thus, the vid22Δ mutation was suggested to cause a defect in the Psd2p activity. Furthermore, vid22Δ cells were shown to be defective in expression of the PSD2 gene tagged with 6×HA, the defect being ameliorated by replacement of the native promoter of the PSD2 gene with a CYC1 promoter. In addition, an α-galactosidase reporter assay revealed that the activity of the promoter of the PSD2 gene in vid22Δ cells was ∼5% of that in wild-type cells. These results showed that VID22 is required for transcriptional activation of the PSD2 gene. © 2015 Authors; published by Portland Press Limited.

  9. Active Well Counting Using New PSD Plastic Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Hausladen, Paul [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Newby, Jason [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); McElroy, Robert Dennis [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-11-01

    This report presents results and analysis from a series of proof-of-concept measurements to assess the suitability of segmented detectors constructed from Eljen EJ-299-34 PSD-plastic scintillator with pulse-shape discrimination capability for the purposes of quantifying uranium via active neutron coincidence counting. Present quantification of bulk uranium materials for international safeguards and domestic materials control and accounting relies on active neutron coincidence counting systems, such as the Active Well Coincidence Counter (AWCC) and the Uranium Neutron Coincidence Collar (UNCL), that use moderated He-3 proportional counters along with necessarily low-intensity 241Am(Li) neutron sources. Scintillation-based fast-neutron detectors are a potentially superior technology to the existing AWCC and UNCL designs due to their spectroscopic capability and their inherently short neutron coincidence times that largely eliminate random coincidences and enable interrogation by stronger sources. One of the past impediments to the investigation and adoption of scintillation counters for the purpose of quantifying bulk uranium was the commercial availability of scintillators having the necessary neutron-gamma pulse-shape discrimination properties only as flammable liquids. Recently, Eljen EJ-299-34 PSD-plastic scintillator became commercially available. The present work is the first assessment of an array of PSD-plastic detectors for the purposes of quantifying bulk uranium. The detector panel used in the present work was originally built as the focal plane for a fast-neutron imager, but it was repurposed for the present investigation by construction of a stand to support the inner well of an AWCC immediately in front of the detector panel. The detector panel and data acquisition of this system are particularly well suited for performing active-well fast-neutron counting of LEU and HEU samples because the active detector volume is solid, the 241Am(Li) interrogating

  10. 75 FR 70254 - PSD and Title V Permitting Guidance for Greenhouse Gases

    Science.gov (United States)

    2010-11-17

    ... AGENCY PSD and Title V Permitting Guidance for Greenhouse Gases AGENCY: Environmental Protection Agency... the EPA has posted its guidance titled, ``PSD and Title V Permitting Guidance for Greenhouse Gases... for Greenhouse Gases.'' This document has been determined to be an EPA Significant Guidance Document...

  11. 76 FR 23489 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR...

    Science.gov (United States)

    2011-04-27

    ..., ``Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Reconsideration of... AGENCY 40 CFR Parts 51 and 52 RIN 2060-AQ73 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Reconsideration of Inclusion of Fugitive Emissions; Interim Rule; Stay...

  12. 75 FR 6823 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR...

    Science.gov (United States)

    2010-02-11

    ... AGENCY 40 CFR Parts 51 and 52 RIN 2060-AP73 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Reconsideration of Inclusion of Fugitive Emissions; Proposal for... emissions requirements in the federal Prevention of Significant Deterioration (PSD) program published in the...

  13. 75 FR 27191 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation

    Science.gov (United States)

    2010-05-14

    ... AGENCY 40 CFR Parts 51 and 52 RIN 2060-AP80 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... period on our proposed reconsideration of the Prevention of Significant Deterioration (PSD) and...

  14. Thermodynamics of TMPC/PSd/Fullerene Nanocomposites: SANS Study

    KAUST Repository

    Chua, Yang-Choo

    2010-11-23

    Wereport a small angle neutron scattering study of the thermodynamics of a polymer mixture in the presence of nanoparticles, both in equilibrium and during phase separation. Neutron cloud point measurements and random phase approximation (RPA) analysis demonstrate that 1-2 mass % of C60 fullerenes destabilizes a highly interacting mixture of poly(tetramethyl bisphenol A polycarbonate) and deuterated polystyrene (TMPC/PSd). We unequivocally corroborate these findings with time-resolved temperature jump experiments that, in identical conditions, result in phase separation for the nanocomposite and stability for the neat polymer mixture. At lower C 60 loadings (viz. 0.2-0.5 mass %), stabilization of the mixture is observed. The nonmonotonic variation of the spinodal temperature with fullerene addition suggests a competitive interplay of asymmetric component interactions and nanoparticle dispersion. The stability line shift depends critically on particle dispersion and vanishes upon nanoparticle agglomeration. © 2010 American Chemical Society.

  15. Final PSD Permit Extension Letter - Energy Answers Arecibo, LLC/Energy Answers Arecibo Puerto Rico Renewable Energy Project, PR

    Science.gov (United States)

    This page contains the Final PSD Permit Extension Letter for Energy Answers Arecibo Puerto Rico Renewable Energy Project, issued on April 10, 2017 and the EPA Public Announcement for Final PSD Permit Extension for Energy Answers Arecibo, PR.

  16. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

    DEFF Research Database (Denmark)

    Zheng, Sika; Gray, Erin E; Chawla, Geetanjali

    2012-01-01

    Postsynaptic density protein 95 (PSD-95) is essential for synaptic maturation and plasticity. Although its synaptic regulation has been widely studied, the control of PSD-95 cellular expression is not understood. We found that Psd-95 was controlled post-transcriptionally during neural development...

  17. Maximum Likelihood PSD Estimation for Speech Enhancement in Reverberation and Noise

    DEFF Research Database (Denmark)

    Kuklasinski, Adam; Doclo, Simon; Jensen, Søren Holdt

    2016-01-01

    In this contribution we focus on the problem of power spectral density (PSD) estimation from multiple microphone signals in reverberant and noisy environments. The PSD estimation method proposed in this paper is based on the maximum likelihood (ML) methodology. In particular, we derive a novel ML...... instrumental measures and is shown to be higher than when the competing estimator is used. Moreover, we perform a speech intelligibility test where we demonstrate that both the proposed and the competing PSD estimators lead to similar intelligibility improvements....

  18. POWER SPECTRUM DENSITY (PSD ANALYSIS OF AUTOMOTIVE PEDAL-PAD

    Directory of Open Access Journals (Sweden)

    AHMED RITHAUDDEEN YUSOFF

    2016-04-01

    Full Text Available Vibration at the pedal-pad may contribute to discomfort of foot plantar fascia during driving. This is due to transmission of vibration to the mount, chassis, pedal, and then to the foot plantar fascia. This experimental study is conducted to determine the estimation of peak value using the power spectral density of the vertical vibration input at the foot. The power spectral density value is calculated based on the frequency range between 13 Hz to 18 Hz. This experiment was conducted using 12 subjects testing on three size of pedal-pads; small, medium and large. The result shows that peak value occurs at resonance frequency of 15 Hz. The PSD values at that resonance frequency are 0.251 (m/s2 2/Hz for small pedal-pad, followed by the medium pedal-pad is at 0.387 (m/s2 2/Hz and lastly for the large pedal-pad is at 0.483 (m/s22/Hz. The resultsindicate that during driving, the foot vibration when interact with the large pedal-pad contributed higher stimulus compared with the small and medium pedal-pad. The pedal-pad size plays an important role in the pedal element designs in terms of vibration-transfer from pedal-pads on the feet, particularly to provide comfort to the driver while driving.

  19. Handout on Health: Osteoporosis

    Science.gov (United States)

    ... to prevent bone loss and fractures. Bone Cell Biology Scientists are exploring the biochemical pathways and cellular ... Occasionally, new information on medication is released. For updates and for any questions about any medications you ...

  20. Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

    DEFF Research Database (Denmark)

    Fiorentini, Monica; Bach, Anders; Strømgaard, Kristian

    2013-01-01

    the extreme C-terminus of GluD2 with PSD-93 PDZ1 have been investigated in the crystalline phase. Two different binding modes of these residues were observed, suggesting that the peptide is not tightly bound to PSD-93 PDZ1. In accordance, the two N-terminal PSD-93 PDZ domains show no appreciable binding...... affinity for a GluD2-derived C-terminal octapeptide, whereas micromolar affinity was observed for a GluN2B-derived C-terminal octapeptide. This indicates that if present, the interactions between GluD2 and PSD-93 involve more than the extreme terminus of the receptor. In contrast, the tumour...

  1. Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

    Directory of Open Access Journals (Sweden)

    Esperanza Fernández

    2017-10-01

    Full Text Available Arc is an activity-regulated neuronal protein, but little is known about its interactions, assembly into multiprotein complexes, and role in human disease and cognition. We applied an integrated proteomic and genetic strategy by targeting a tandem affinity purification (TAP tag and Venus fluorescent protein into the endogenous Arc gene in mice. This allowed biochemical and proteomic characterization of native complexes in wild-type and knockout mice. We identified many Arc-interacting proteins, of which PSD95 was the most abundant. PSD95 was essential for Arc assembly into 1.5-MDa complexes and activity-dependent recruitment to excitatory synapses. Integrating human genetic data with proteomic data showed that Arc-PSD95 complexes are enriched in schizophrenia, intellectual disability, autism, and epilepsy mutations and normal variants in intelligence. We propose that Arc-PSD95 postsynaptic complexes potentially affect human cognitive function.

  2. PSD microscopy: a new technique for adaptive local scanning of microscale objects.

    Science.gov (United States)

    Rahimi, Mehdi; Shen, Yantao

    2017-01-01

    A position-sensitive detector/device (PSD) is a sensor that is capable of tracking the location of a laser beam on its surface. PSDs are used in many scientific instruments and technical applications including but not limited to atomic force microscopy, human eye movement monitoring, mirrors or machine tool alignment, vibration analysis, beam position control and so on. This work intends to propose a new application using the PSD. That is a new microscopy system called scanning PSD microscopy. The working mechanism is about putting an object on the surface of the PSD and fast scanning its area with a laser beam. To achieve a high degree of accuracy and precision, a reliable framework was designed using the PSD. In this work, we first tried to improve the PSD reading and its measurement performance. This was done by minimizing the effects of noise, distortion and other disturbing parameters. After achieving a high degree of confidence, the microscopy system can be implemented based on the improved PSD measurement performance. Later to improve the scanning efficiency, we developed an adaptive local scanning system to scan the whole area of the PSD in a short matter of time. It was validated that our comprehensive and adaptive local scanning method can shorten the scanning time in order of hundreds of times in comparison with the traditional raster scanning without losing any important information about the scanned 2D objects. Methods are also introduced to scan very complicated objects with bifurcations and crossings. By incorporating all these methods, the new microscopy system is capable of scanning very complicated objects in the matter of a few seconds with a resolution that is in order of a few micrometers.

  3. Small RNAs regulate the biocontrol property of fluorescent Pseudomonas strain Psd.

    Science.gov (United States)

    Upadhyay, Anamika; Kochar, Mandira; Upadhyay, Ashutosh; Tripathy, Soumya; Rajam, Manchikatla Venkat; Srivastava, Sheela

    2017-03-01

    The production of biocontrol factors by Pseudomonads is reported to be controlled at the post-transcriptional level by the GacS/GacA signal transduction pathway. This involves RNA-binding translational repressor proteins, RsmA and RsmE, and the small regulatory RNAs (sRNAs) RsmX, RsmY, and RsmZ. While the former represses genes involved in secondary metabolite production, the latter relieves this repression at the end of exponential growth. We have studied the fluorescent Pseudomonas strain Psd, possessing good biocontrol potential, and confirmed the presence of rsmY and rsmZ by PCR amplification. Gene constructs for all the three small RNAs (RsmX, RsmY and RsmZ) carried on broad host-range plasmid, pME6032 were mobilized into strain Psd. Expression analysis of gacA in the recombinant strains over-expressing rsmX (Psd-pME7320), rsmY (Psd-pME6359) and rsmZ (Psd-pME6918) revealed a significant upregulation of the response regulator. Besides, a remarkable down-regulation of rsmA was also reported in all the strains. The variant strains were found to produce comparatively higher levels of phenazines. Indole acetic acid levels were higher to some extent, and strain Psd-pME6918 also showed elevated production of HCN. The tomato seedlings infected with Fusarium oxysporum and Verticillium dahliae in the presence of culture filtrate of the recombinant strains showed better plant protection response in comparison to the wild-type strain Psd. These results suggest that small RNAs are important determinants in regulation of the biocontrol property of strain Psd. Copyright © 2016 Elsevier GmbH. All rights reserved.

  4. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins.

    Science.gov (United States)

    Fortin, Dale A; Tillo, Shane E; Yang, Guang; Rah, Jong-Cheol; Melander, Joshua B; Bai, Suxia; Soler-Cedeño, Omar; Qin, Maozhen; Zemelman, Boris V; Guo, Caiying; Mao, Tianyi; Zhong, Haining

    2014-12-10

    Stoichiometric labeling of endogenous synaptic proteins for high-contrast live-cell imaging in brain tissue remains challenging. Here, we describe a conditional mouse genetic strategy termed endogenous labeling via exon duplication (ENABLED), which can be used to fluorescently label endogenous proteins with near ideal properties in all neurons, a sparse subset of neurons, or specific neuronal subtypes. We used this method to label the postsynaptic density protein PSD-95 with mVenus without overexpression side effects. We demonstrated that mVenus-tagged PSD-95 is functionally equivalent to wild-type PSD-95 and that PSD-95 is present in nearly all dendritic spines in CA1 neurons. Within spines, while PSD-95 exhibited low mobility under basal conditions, its levels could be regulated by chronic changes in neuronal activity. Notably, labeled PSD-95 also allowed us to visualize and unambiguously examine otherwise-unidentifiable excitatory shaft synapses in aspiny neurons, such as parvalbumin-positive interneurons and dopaminergic neurons. Our results demonstrate that the ENABLED strategy provides a valuable new approach to study the dynamics of endogenous synaptic proteins in vivo. Copyright © 2014 the authors 0270-6474/14/3416698-15$15.00/0.

  5. Stabilization of the angiotensin-(1-7) receptor Mas through interaction with PSD95.

    Science.gov (United States)

    Bian, Weihua; Sun, Licui; Yang, Longyan; Li, Ji-Feng; Hu, Jia; Zheng, Shuai; Guo, Ruihan; Feng, Duiping; Ma, Qian; Shi, Xiaocui; Xiong, Ying; Yang, Xiaomei; Song, Ran; Xu, Jianguo; Wang, Songlin; He, Junqi

    2013-08-01

    The functions and signalling mechanisms of the Ang-(1-7) [angiotensin-(1-7)] receptor Mas have been studied extensively. However, less attention has been paid to the intracellular regulation of Mas protein. In the present study, PSD95 (postsynaptic density 95), a novel binding protein of Mas receptor, was identified, and their association was characterized further. Mas specifically interacts with PDZ1-2, but not the PDZ3, domain of PSD95 via Mas-CT (Mas C-terminus), and the last four amino acids [ETVV (Glu-Thr-Val-Val)] of Mas-CT were determined to be essential for this interaction, as shown by GST pull-down, co-immunoprecipitation and confocal co-localization experiments. Gain-of-function and loss-of-function studies indicated that PSD95 enhanced Mas protein expression by increasing the stabilization of the receptor. Mas degradation was robustly inhibited by the proteasome inhibitor MG132 in time- and dose-dependent manners, and the expression of PSD95 impaired Mas ubiquitination, indicating that the PSD95-Mas association inhibits Mas receptor degradation via the ubiquitin-proteasome proteolytic pathway. These findings reveal a novel mechanism of Mas receptor regulation by which its expression is modulated at the post-translational level by ubiquitination, and clarify the role of PSD95, which binds directly to Mas, blocking the ubiquitination and subsequent degradation of the receptor via the ubiquitin-proteasome proteolytic pathway.

  6. An app with remote support achieves better adherence to home exercise programs than paper handouts in people with musculoskeletal conditions: a randomised trial.

    Science.gov (United States)

    Lambert, Tara E; Harvey, Lisa A; Avdalis, Christos; Chen, Lydia W; Jeyalingam, Sayanthinie; Pratt, Carin A; Tatum, Holly J; Bowden, Jocelyn L; Lucas, Barbara R

    2017-07-01

    Do people with musculoskeletal conditions better adhere to their home exercise programs when these are provided to them on an app with remote support compared to paper handouts? Randomised, parallel-group trial with intention-to-treat analysis. Eighty participants with upper or lower limb musculoskeletal conditions were recruited to the trial. Each participant was prescribed a 4-week home exercise program by a physiotherapist at a tertiary teaching hospital in Australia. Participants were randomly assigned via a computer-generated concealed block randomisation procedure to either intervention (n=40) or control (n=40) groups. Participants in the intervention group received their home exercise programs on an app linked to the freely available website www.physiotherapyexercises.com. They also received supplementary phone calls and motivational text messages. Participants in the control group received their home exercise programs as a paper handout. Blinded assessors collected outcome measures at baseline and 4 weeks. The primary outcome was self-reported exercise adherence. There were five secondary outcomes, which captured functional performance, disability, patient satisfaction, perceptions of treatment effectiveness, and different aspects of adherence. Outcomes were available on 77 participants. The mean between-group difference for self-reported exercise adherence at 4 weeks was 1.3/11 points (95% CI 0.2 to 2.3), favouring the intervention group. The mean between-group difference for function was 0.9/11 points (95% CI 0.1 to 1.7) on the Patient-Specific Functional Scale, also favouring the intervention group. There were no significant between-group differences for the remaining outcomes. People with musculoskeletal conditions adhere better to their home exercise programs when the programs are provided on an app with remote support compared to paper handouts; however, the clinical importance of this added adherence is unclear. ACTRN12616000066482. [Lambert TE

  7. Novel Method of Detecting Movement of the Interference Fringes Using One-Dimensional PSD

    Directory of Open Access Journals (Sweden)

    Qi Wang

    2015-06-01

    Full Text Available In this paper, a method of using a one-dimensional position-sensitive detector (PSD by replacing charge-coupled device (CCD to measure the movement of the interference fringes is presented first, and its feasibility is demonstrated through an experimental setup based on the principle of centroid detection. Firstly, the centroid position of the interference fringes in a fiber Mach-Zehnder (M-Z interferometer is solved in theory, showing it has a higher resolution and sensitivity. According to the physical characteristics and principles of PSD, a simulation of the interference fringe’s phase difference in fiber M-Z interferometers and PSD output is carried out. Comparing the simulation results with the relationship between phase differences and centroid positions in fiber M-Z interferometers, the conclusion that the output of interference fringes by PSD is still the centroid position is obtained. Based on massive measurements, the best resolution of the system is achieved with 5.15, 625 μm. Finally, the detection system is evaluated through setup error analysis and an ultra-narrow-band filter structure. The filter structure is configured with a one-dimensional photonic crystal containing positive and negative refraction material, which can eliminate background light in the PSD detection experiment. This detection system has a simple structure, good stability, high precision and easily performs remote measurements, which makes it potentially useful in material small deformation tests, refractivity measurements of optical media and optical wave front detection.

  8. Impairment of TrkB-PSD-95 signaling in Angelman syndrome.

    Directory of Open Access Journals (Sweden)

    Cong Cao

    Full Text Available Angelman syndrome (AS is a neurodevelopment disorder characterized by severe cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, required for the proteasomal degradation of proteins implicated in synaptic plasticity, such as the activity-regulated cytoskeletal-associated protein (Arc/Arg3.1. Mice deficient in maternal Ube3A express elevated levels of Arc in response to synaptic activity, which coincides with severely impaired long-term potentiation (LTP in the hippocampus and deficits in learning behaviors. In this study, we sought to test whether elevated levels of Arc interfere with brain-derived neurotrophic factor (BDNF TrkB receptor signaling, which is known to be essential for both the induction and maintenance of LTP. We report that TrkB signaling in the AS mouse is defective, and show that reduction of Arc expression to control levels rescues the signaling deficits. Moreover, the association of the postsynaptic density protein PSD-95 with TrkB is critical for intact BDNF signaling, and elevated levels of Arc were found to impede PSD-95/TrkB association. In Ube3A deficient mice, the BDNF-induced recruitment of PSD-95, as well as PLCγ and Grb2-associated binder 1 (Gab1 with TrkB receptors was attenuated, resulting in reduced activation of PLCγ-α-calcium/calmodulin-dependent protein kinase II (CaMKII and PI3K-Akt, but leaving the extracellular signal-regulated kinase (Erk pathway intact. A bridged cyclic peptide (CN2097, shown by nuclear magnetic resonance (NMR studies to uniquely bind the PDZ1 domain of PSD-95 with high affinity, decreased the interaction of Arc with PSD-95 to restore BDNF-induced TrkB/PSD-95 complex formation, signaling, and facilitate the induction of LTP in AS mice. We propose that the failure of TrkB receptor signaling at synapses in AS is directly linked to elevated levels of Arc associated with PSD-95 and PSD-95

  9. Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95

    DEFF Research Database (Denmark)

    Eildal, Jonas N N; Bach, Anders; Dogan, Jakob

    2015-01-01

    PSD-95 is a scaffolding protein of the MAGUK protein family, and engages in several vital protein-protein interactions in the brain with its PDZ domains. It has been suggested that PSD-95 is composed of two supramodules, one of which is the PDZ1-2 tandem domain. Here we have developed rigidified...

  10. Design and synthesis of triazole-based peptidomimetics of a PSD-95 PDZ domain inhibitor

    DEFF Research Database (Denmark)

    Bach, Anders; Pedersen, Thomas B.; Strømgaard, Kristian

    2016-01-01

    PSD-95 PDZ domains are biologically important and promising drug targets. Here, we discover a triazole-based peptidomimetic, 10, by ‘click chemistry’. Compound 10 inhibits the PDZ2/GluN2B interaction with affinity similar to tripeptide SAV and better than current small-molecules. Thus, 10...

  11. Maximum likelihood PSD estimation for speech enhancement in reverberant and noisy conditions

    DEFF Research Database (Denmark)

    Kuklasinski, Adam; Doclo, Simon; Jensen, Jesper

    2016-01-01

    estimator. Instrumental performance measures indicate an advantage of the proposed estimator over the competing one. In a speech intelligibility test all algorithms significantly improved the word intelligibility score. While the results suggest a minor advantage of using the proposed PSD estimator...

  12. Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.

    Science.gov (United States)

    Fossati, G; Morini, R; Corradini, I; Antonucci, F; Trepte, P; Edry, E; Sharma, V; Papale, A; Pozzi, D; Defilippi, P; Meier, J C; Brambilla, R; Turco, E; Rosenblum, K; Wanker, E E; Ziv, N E; Menna, E; Matteoli, M

    2015-09-01

    Impairment of synaptic function can lead to neuropsychiatric disorders collectively referred to as synaptopathies. The SNARE protein SNAP-25 is implicated in several brain pathologies and, indeed, brain areas of psychiatric patients often display reduced SNAP-25 expression. It has been recently found that acute downregulation of SNAP-25 in brain slices impairs long-term potentiation; however, the processes through which this occurs are still poorly defined. We show that in vivo acute downregulation of SNAP-25 in CA1 hippocampal region affects spine number. Consistently, hippocampal neurons from SNAP-25 heterozygous mice show reduced densities of dendritic spines and defective PSD-95 dynamics. Finally, we show that, in brain, SNAP-25 is part of a molecular complex including PSD-95 and p140Cap, with p140Cap being capable to bind to both SNAP-25 and PSD-95. These data demonstrate an unexpected role of SNAP-25 in controlling PSD-95 clustering and open the possibility that genetic reductions of the protein levels - as occurring in schizophrenia - may contribute to the pathology through an effect on postsynaptic function and plasticity.

  13. Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence.

    Science.gov (United States)

    Fernández, Esperanza; Collins, Mark O; Frank, René A W; Zhu, Fei; Kopanitsa, Maksym V; Nithianantharajah, Jess; Lemprière, Sarah A; Fricker, David; Elsegood, Kathryn A; McLaughlin, Catherine L; Croning, Mike D R; Mclean, Colin; Armstrong, J Douglas; Hill, W David; Deary, Ian J; Cencelli, Giulia; Bagni, Claudia; Fromer, Menachem; Purcell, Shaun M; Pocklington, Andrew J; Choudhary, Jyoti S; Komiyama, Noboru H; Grant, Seth G N

    2017-10-17

    Arc is an activity-regulated neuronal protein, but little is known about its interactions, assembly into multiprotein complexes, and role in human disease and cognition. We applied an integrated proteomic and genetic strategy by targeting a tandem affinity purification (TAP) tag and Venus fluorescent protein into the endogenous Arc gene in mice. This allowed biochemical and proteomic characterization of native complexes in wild-type and knockout mice. We identified many Arc-interacting proteins, of which PSD95 was the most abundant. PSD95 was essential for Arc assembly into 1.5-MDa complexes and activity-dependent recruitment to excitatory synapses. Integrating human genetic data with proteomic data showed that Arc-PSD95 complexes are enriched in schizophrenia, intellectual disability, autism, and epilepsy mutations and normal variants in intelligence. We propose that Arc-PSD95 postsynaptic complexes potentially affect human cognitive function. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  14. Design of a large dynamic range readout unit for the PSD detector of DAMPE

    CERN Document Server

    Zhou, Yong; Sun, Zhiyu; Zhang, Yongjie; Fang, Fang; Chen, Junling; Hu, Bitao

    2016-01-01

    A large dynamic range is required by the Plastic Scintillator Detector (PSD) of DArk Matter Paricle Explorer (DAMPE), and a double-dynode readout has been developed. To verify this design, a prototype detector module has been constructed and tested with cosmic rays and heavy ion beams. The results match with the estimation and the readout unit could easily cover the required dynamic range.

  15. 75 FR 28227 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation

    Science.gov (United States)

    2010-05-20

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Parts 51 and 52 RIN 2060-AP80 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation Correction Proposed Rule document 2010-11578 was...

  16. What does it mean to be pseudo single domain? Demystifying the PSD state

    Science.gov (United States)

    Lascu, I.; Harrison, R. J.; Einsle, J. F.; Ball, M.

    2016-12-01

    Until recently, non-interacting stable single domain grains were thought to be the sole reliable paleomagnetic recorders. However most natural samples contain so-called "non-ideal" paleomagnetic recorders, which are either interacting single domain particles, or magnetic grains larger than single domain grains, but smaller than proper multi domain grains, which are poor paleomagnetic recorders. The grain size range for these recorders, which for magnetite comprises grains from 100 nm to a few μm in size, is known as the pseudo single domain (PSD) state. Natural samples containing abundant PSD grains have been shown time and again to reliably record thermomagnetic remanent magnetizations that are stable over billions of years. Here we attempt to shed new light on the PSD state by investigating obsidian varieties found at Glass Butte, Oregon, which present the opportunity to study simple cases of magnetic grains encapsulated in volcanic glass. We do this by combining rock magnetism, scanning electron microscopy (SEM) nanotomography, and finite-element micromagnetic modeling. Using rock magnetism we have identified PSD signatures in these samples via their fingerprint in first-order reversal curve (FORC) diagrams. Tomographic reconstructions obtained by stacking SEM images acquired via sequential milling through sample volumes of a few tens of cubic μm reveal the presence of abundant grains that span the PSD grain size interval. These grains have a variety of shapes, from simple ellipsoidal particles, to more complex morphologies attained through the coalescence of neighboring grains during crystallization, to intricate "rolling snowball" morphologies in larger grains that contain appendices formed as a result of particle growth in a dynamic environment as the flowing lava cooled. Micromagnetic modeling of the simplest morphologies reveals that these grains are in single vortex states, with the remanence controlled by irregularities in grain morphology. Coalesced

  17. Plastic Bonded Explosive (PBX) Particle Size Distribution (PSD) Measurements Using an Image Analysis System

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Gregg K. [Univ. of Wyoming, Laramie, WY (United States)

    2003-06-01

    The slurry process for producing plastic bonded explosives (PBX) has been used for many years. However, until recently the mechanisms involved have not been studied quantitatively to determine the effects of the various control variables. Recently, the effects of operating variables on the final product have been studied; however, no attempt was made to measure particle growth during the slurry process. This study applies an image analysis tool to measure particle size distributions (PSDs) during the slurry process to produce PBX 9501, a specific formulation used in nuclear weapons. The observed PBX 9501 slurry behavior leads away from the typical population balance description of agglomeration, that is, a discrete particle-particle coalescence mechanism. The behavior observed in these experiments indicates that the initial state of the system contains a number of smaller particles clustered together. The cluster then coalesces into a large particle as solvent is removed and the slurry continuously mixed. Other small fragments are picked up and a relatively small amount of growth is observed. A mass transfer model adequately describes solvent removal, and an empirical model is developed to describe the growth behavior in terms of measured process variables. The image system is applied to dried molding powders. The PSD measurement results of the PBX 9501 library lots, historic samples set aside as PBX 9501 lots were accepted from the manufacturer, are also discussed and analyzed. A correlation analysis was conducted to find relationships between the measured PSD and other properties such as bulk density and pressed densities. While no significant correlation was found between the measured PSD and averaged bulk densities for the library lots, significant correlations are found between the measured PSD and pressed density. The final part of the study was to scale-up the PSD measurement capability. Since the large-scale processes are not yet operational, this work

  18. Ocean thermal energy conversion power system development. Final design report: PSD-I, Phase II

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-30

    The PSD-I program provides a heat exchanger sytem consisting of an evaporator, condenser and various ancillaries with ammonia used as a working fluid in a closed simulated Rankine cycle. It is to be installed on the Chepachet Research Vessel for test and evaluation of a number of OTEC concepts in a true ocean environment. It is one of several test articles to be tested. Primary design concerns include control of biofouling, corrosion and erosion of aluminum tubes, selection of materials, and the development of a basis for scale-up to large heat exchangers so as to ultimately demonstrate economic feasibility on a commercial scale. The PSD-I test article is devised to verify thermodynamic, environmental, and mechanical performance of basic design concepts. The detailed design, development, fabrication, checklist, delivery, installation support, and operation support for the Test Article Heat Exchangers are described. (WHK)

  19. Marshall Space Flight Center Propulsion Systems Department (PSD) Knowledge Management (KM) Initiative

    Science.gov (United States)

    Caraccioli, Paul; Varnedoe, Tom; Smith, Randy; McCarter, Mike; Wilson, Barry; Porter, Richard

    2006-01-01

    NASA Marshall Space Flight Center's Propulsion Systems Department (PSD) is four months into a fifteen month Knowledge Management (KM) initiative to support enhanced engineering decision making and analyses, faster resolution of anomalies (near-term) and effective, efficient knowledge infused engineering processes, reduced knowledge attrition, and reduced anomaly occurrences (long-term). The near-term objective of this initiative is developing a KM Pilot project, within the context of a 3-5 year KM strategy, to introduce and evaluate the use of KM within PSD. An internal NASA/MSFC PSD KM team was established early in project formulation to maintain a practitioner, user-centric focus throughout the conceptual development, planning and deployment of KM technologies and capabilities within the PSD. The PSD internal team is supported by the University of Alabama's Aging Infrastructure Systems Center of Excellence (AISCE), lntergraph Corporation, and The Knowledge Institute. The principle product of the initial four month effort has been strategic planning of PSD KNI implementation by first determining the "as is" state of KM capabilities and developing, planning and documenting the roadmap to achieve the desired "to be" state. Activities undertaken to suppoth e planning phase have included data gathering; cultural surveys, group work-sessions, interviews, documentation review, and independent research. Assessments and analyses have beon pedormed including industry benchmarking, related local and Agency initiatives, specific tools and techniques used and strategies for leveraging existing resources, people and technology to achieve common KM goals. Key findings captured in the PSD KM Strategic Plan include the system vision, purpose, stakeholders, prioritized strategic objectives mapped to the top ten practitioner needs and analysis of current resource usage. Opportunities identified from research, analyses, cultural1KM surveys and practitioner interviews include

  20. Simulated power spectral density (PSD) of background electrocorticogram (ECoG).

    Science.gov (United States)

    Freeman, Walter J; Zhai, Jian

    2009-03-01

    The ECoG background activity of cerebral cortex in states of rest and slow wave sleep resembles broadband noise. The power spectral density (PSD) then may often conform to a power-law distribution: a straight line in coordinates of log power vs. log frequency. The exponent, x, of the distribution, 1/f(x), ranges between 2 and 4. These findings are explained with a model of the neural source of the background activity in mutual excitation among pyramidal cells. The dendritic response of a population of interactive excitatory neurons to an impulse input is a rapid exponential rise and a slow exponential decay, which can be fitted with the sum of two exponential terms. When that function is convolved as the kernel with pulses from a Poisson process and summed, the resulting "brown" or "black noise conforms to the ECoG time series and the PSD in rest and sleep. The PSD slope is dependent on the rate of rise. The variation in the observed slope is attributed to variation in the level of the background activity that is homeostatically regulated by the refractory periods of the excitatory neurons. Departures in behavior from rest and sleep to action are accompanied by local peaks in the PSD, which manifest emergent nonrandom structure in the ECoG, and which prevent reliable estimation of the 1/f(x) exponents in active states. We conclude that the resting ECoG truly is low-dimensional noise, and that the resting state is an optimal starting point for defining and measuring both artifactual and physiological structures emergent in the activated ECoG.

  1. Writing Like a Scientist: Exploring Elementary Teachers' Understandings and Practices of Writing in Science

    Science.gov (United States)

    Glen, Nicole J.; Dotger, Sharon

    2013-01-01

    This qualitative study examined the connections between elementary teachers' conceptions of how scientists use writing and how the teachers used writing during science lessons. Data collected included lesson observations, interviews, handouts to students, and curriculum resources. The findings revealed that teachers in this study thought…

  2. Tank Farm WM-182 and WM 183 Heel Slurry Samples PSD Results

    Energy Technology Data Exchange (ETDEWEB)

    Batcheller, Thomas Aquinas

    2000-09-01

    Particle size distribution (PSD) analysis of INTEC Tank Farm WM-182 and WM-183 heel slurry samples were performed using a modified Horiba LA-300 PSD analyzer at the RAL facility. There were two types of testing performed: typical PSD analysis, and setting rate testing. Although the heel slurry samples were obtained from two separate vessels, the particle size distribution results were quite similar. The slurry solids were from approximately a minimum particle size of 0.5 mm to a maximum of 230 mm-with about 90% of the material between 2-to-133 mm, and the cumulative 50% value at approximately 20 mm. This testing also revealed that high frequency sonication with an ultrasonic element may break-up larger particles in the WM-182 and WM-183 tank from heel slurries. This finding represents useful information regarding ultimate tank heel waste processing. Settling rate testing results were also fairly consistent with material from both vessels in that it appears that most of the mass of solids settle to an agglomerated, yet easily redispersed layer at the bottom. A dispersed and suspended material remained in the "clear" layer above the settled layer after about one-half an hour of settling time. This material had a statistical mode of approximately 5 mm and a maximum particle size of 30 mm.

  3. PSD95 gene specific siRNAs attenuate neuropathic pain through modulating neuron sensibility and postsynaptic CaMKIIα phosphorylation.

    Science.gov (United States)

    Le, Shen; Xu, Li; Wen, Chen; Li, Xu; Wei, Liu; Xue-rong, Yu; Yu-guang, Huang

    2011-12-01

    To observe the effects of PSD95 gene specific siRNAs on neuropathic pain relief, neuron viability, and postsynaptic calcium/calmodulin-dependent protein kinase IIα (CaMKIIα) phosphorylation in vitro and in vivo. Gene-specific siRNAs of rat PSD95 were synthesized chemically for transfection. Adult male Sprague-Dawley (SD) rats were randomly divided into 3 groups: naïve group (n=6), sham group (n=6), and sciatic nerve chronic constriction injury (CCI) group (n=24). The CCI group was further divided into 4 groups (n=6 in each group), which were pretreated with normal saline, transfection vehicle, negative control siRNAs, and PSD95 gene specific siRNAs respectively. All the subgroups received corresponding agents intrathecally for 3 days, started one day before the CCI of sciatic nerve. Both mechanical allodynia and thermal hyperalgesia were measured on post-operative day 3 and 7. PSD95 gene silenced NG108-15 cells were further stimulated by glutamate, with the cell viability and the expression/phosphorylation of CaMKIIα measured by MTT cell proliferation assay and Western blot, respectively. The siRNAs decreased PSD95 mRNA level significantly both in vivo and in vitro. Neuropathic pain rats pretreated with PSD95 gene specific siRNAs exhibited significant elevation in the mechanical withdrawal threshold and paw withdrawal thermal latency, without affecting the baseline nociception. PSD95 gene silencing enhanced neuronal tolerance against the glutamate excitotoxicity, meanwhile the phosphorylation of CaMKIIα Thr286 was attenuated. Pre-emptive administration of PSD95 gene specific siRNAs may attenuate the central sensitization CaMKIIα-related signaling cascades, leading to the relief of neuropathic pain.

  4. Comparing the response of PSD-capable plastic scintillator to standard liquid scintillator

    Science.gov (United States)

    Woolf, Richard S.; Hutcheson, Anthony L.; Gwon, Chul; Phlips, Bernard F.; Wulf, Eric A.

    2015-06-01

    This work discusses a test campaign to characterize the response of the recently developed plastic scintillator with pulse shape discrimination (PSD) capabilities (EJ-299-33). PSD is a property exhibited by certain types of scintillating material in which incident stimuli (fast neutrons or γ rays) can be separated by exploiting differences in the scintillation light pulse tail. Detector geometries used were: a 10 cm×10 cm×10 cm cube and a 10-cm diameter×10-cm long cylinder. EJ-301 and EJ-309 liquid scintillators with well-known responses were also tested. The work was conducted at the University of Massachusetts Lowell Van De Graaff accelerator. The facility accelerated protons on a thin Li target to yield quasi-monoenergetic neutrons from the 7Li(p,n)7Be reaction (Q-value: -1.644 MeV). Collimated fast neutrons were obtained by placing detectors behind a neutron spectrometer. Rotating the spectrometer, and thus changing the neutron energy, allowed us to achieve 0.5-3.2 MeV neutrons in 200-300 keV steps. Data were acquired through a flash analog-to-digital converter (ADC) capable of performing digital PSD measurements. By using the PSD technique to separate the neutron events from unwanted γ background, we constructed a pulse height spectrum at each energy. Obtaining a relationship of the relative light output versus energy allowed us to construct the response function for the EJ-299-33 and liquid scintillator. The EJ-299-33 response in terms of electron equivalent energy (Ee.e.) vs. proton equivalent energy (Ep.e.), how it compared with the standard xylene-based EJ-301 (or, NE-213/BC-501 A equivalent) and EJ-309 liquid scintillator response, and how the EJ-301 and EJ-309 compared, are presented. We find that the EJ-299-33 demonstrated a lower light output by up to 40% for environment affected the detector response. We find relatively good agreement between our results and the modeling; however, the observed response could not be fully accounted for due to

  5. PSD Applicability Determination for Power Boiler No. 4 at the Potlatch Corporation Facility in Lewiston, Idaho

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  6. Simpson Pulp and Paper Mill in Tacoma, Washington, PSD applicability determination for Power Boiler No. 7

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  7. Applicability of the PSD Regulations to Certain Modifications Made by Cooper Tire and Rubber Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  8. Tire Derived Fuel Classified as Municipal Solid Waste for a PSD Exemption

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  9. Contingency Plan for FGD Systems During Downtime as a Function of PSD

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  10. Automatic or Blanket Exemptions for Excess Emissions During Startup, and Shutdowns Under PSD

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  11. PSD Applicability Determination for AEG Bovoni Power's Waste-to-Energy Project

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  12. PSD and NSPS Applicability Determination for Guardian Industries' Flat Glass Plant in Corsicana, Texas

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  13. Clarification That BACT Analysis Under PSD is Applicable for A Proposed Modification to the Rotary Kiln

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  14. PSD Analysis for SIP Relaxation in Metropolitan Boston Air Pollution Control District - Eastman Gelatin

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  15. Applicablitiy Determinations on the PSD 100 tpy Major Source Threshold Catergory for Fossil Fuel Boilers Industries

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. Inclusion of Haul Road Emissions in PSD Applicability Determination for Coal Mine and Preparation Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  17. Applicability of PSD and NSPS to the Cleveland Electric, Incorporated, Plant in Willoughby, Ohio

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  18. NSR Advisory Memo # 1 : TSP PSD Increment Consumption in North Carolina

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  19. Simulated and Real Sheet-of-Light 3D Object Scanning Using a-Si:H Thin Film PSD Arrays

    Directory of Open Access Journals (Sweden)

    Javier Contreras

    2015-11-01

    Full Text Available A MATLAB/SIMULINK software simulation model (structure and component blocks has been constructed in order to view and analyze the potential of the PSD (Position Sensitive Detector array concept technology before it is further expanded or developed. This simulation allows changing most of its parameters, such as the number of elements in the PSD array, the direction of vision, the viewing/scanning angle, the object rotation, translation, sample/scan/simulation time, etc. In addition, results show for the first time the possibility of scanning an object in 3D when using an a-Si:H thin film 128 PSD array sensor and hardware/software system. Moreover, this sensor technology is able to perform these scans and render 3D objects at high speeds and high resolutions when using a sheet-of-light laser within a triangulation platform. As shown by the simulation, a substantial enhancement in 3D object profile image quality and realism can be achieved by increasing the number of elements of the PSD array sensor as well as by achieving an optimal position response from the sensor since clearly the definition of the 3D object profile depends on the correct and accurate position response of each detector as well as on the size of the PSD array.

  20. Handout on Health: Back Pain

    Science.gov (United States)

    ... when used as a part of a comprehensive treatment plan for low back pain. Acupressure . A therapist applies pressure to certain places in the body to relieve pain. Acupressure has not been well studied for back pain. Surgical treatments may be necessary in some cases, including: Herniated ( ...

  1. Fuzzy norm method for evaluating random vibration of airborne platform from limited PSD data

    Directory of Open Access Journals (Sweden)

    Wang Zhongyu

    2014-12-01

    Full Text Available For random vibration of airborne platform, the accurate evaluation is a key indicator to ensure normal operation of airborne equipment in flight. However, only limited power spectral density (PSD data can be obtained at the stage of flight test. Thus, those conventional evaluation methods cannot be employed when the distribution characteristics and priori information are unknown. In this paper, the fuzzy norm method (FNM is proposed which combines the advantages of fuzzy theory and norm theory. The proposed method can deeply dig system information from limited data, which probability distribution is not taken into account. Firstly, the FNM is employed to evaluate variable interval and expanded uncertainty from limited PSD data, and the performance of FNM is demonstrated by confidence level, reliability and computing accuracy of expanded uncertainty. In addition, the optimal fuzzy parameters are discussed to meet the requirements of aviation standards and metrological practice. Finally, computer simulation is used to prove the adaptability of FNM. Compared with statistical methods, FNM has superiority for evaluating expanded uncertainty from limited data. The results show that the reliability of calculation and evaluation is superior to 95%.

  2. Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95.

    Science.gov (United States)

    Daut, Rachel A; Busch, Erica F; Ihne, Jessica; Fisher, Daniel; Mishina, Masayoshi; Grant, Seth G N; Camp, Marguerite; Holmes, Andrew

    2015-03-01

    The neural and genetic factors underlying chronic tolerance to alcohol are currently unclear. The GluN2A N-methyl-D-aspartate receptors (NMDAR) subunit and the NMDAR-anchoring protein PSD-95 mediate acute alcohol intoxication and represent putative mechanisms mediating tolerance. We found that chronic intermittent ethanol exposure (CIE) did not produce tolerance [loss of righting reflex (LORR)] or withdrawal-anxiety in C57BL/6J, GluN2A or PSD-95 knockout mice assayed 2-3 days later. However, significant tolerance to LORR was evident 1 day after CIE in C57BL/6J and PSD-95 knockouts, but absent in GluN2A knockouts. These data suggest a role for GluN2A in tolerance, extending evidence that human GluN2A gene variation is involved in alcohol dependence. © 2014 Society for the Study of Addiction.

  3. Effect of complex aerobic physical exercise on PSD-95 in the hippocampus and on cognitive function in juvenile mice

    Science.gov (United States)

    Satriani, W. H.; Redjeki, S.; Kartinah, N. T.

    2017-08-01

    Increased neuroplasticity induced by complex aerobic physical exercise is associated with improved cognitive function in adult mice. Increased cognitive function is assumed to be based on increased synapse formation. One of the regions of the brain that is important in cognitive function is the hippocampus, which plays a role in memory formation. Post synaptic density-95 (PSD-95) is an adhesion protein of the post-synaptic density scaffolding that is essential to synaptic stabilization. As we age, the PSD-95 molecule matures the synapses needed for the formation of the basic circuitry of the nervous system in the brain. However, during the growth period, synapse elimination is higher than its formation. This study aims to determine whether complex aerobic exercise can improve cognitive function and PSD-95 levels in the hippocampus of juvenile mice during their growth stage. The mice performed complex aerobic exercise starting at five weeks of age and continuing for seven weeks with a gradual increase of 8 m/min. At eight weeks it was increased to 10 m/min. The exercise was done for five days of each week. The subjects of the study were tested for cognition one week before being sacrificed (at 12 weeks). The PSD-95 in the hippocampus was measured with ELISA. The results showed that there was a significant difference in cognitive function, where p exercise and a control group that did not. However, the PSD-95 levels did not differ significantly between the two groups. The results of this study indicate that early complex aerobic exercise can improve cognitive ability in adulthood but does not increase the levels of PSD-95 in adults.

  4. PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarisation in cortical spreading depression

    DEFF Research Database (Denmark)

    Kucharz, Krzysztof; Søndergaard Rasmussen, Ida; Bach, Anders

    2017-01-01

    , UCCB01-144 (Tat-N-dimer) ameliorates the persistent effects of cortical spreading depression on cortical function. Using in vivo two-photon microscopy in somatosensory cortex in mice, we show that fluorescently labelled Tat-N-dimer readily crosses blood-brain barrier and accumulates in nerve cells...... depression on cortical blood flow and CMRO2 We suggest that uncoupling of PSD-95 from NMDA receptors reduces overall neuronal excitability and the amplitude of the spreading depolarisation wave. These findings may be of interest for understanding the neuroprotective effects of the nNOS/PSD-95 uncoupling...

  5. Single-Molecule Imaging of PSD-95 mRNA Translation in Dendrites and Its Dysregulation in a Mouse Model of Fragile X Syndrome.

    Science.gov (United States)

    Ifrim, Marius F; Williams, Kathryn R; Bassell, Gary J

    2015-05-06

    Fragile X syndrome (FXS) is caused by the loss of the fragile X mental retardation protein (FMRP), an RNA binding protein that regulates translation of numerous target mRNAs, some of which are dendritically localized. Our previous biochemical studies using synaptoneurosomes demonstrate a role for FMRP and miR-125a in regulating the translation of PSD-95 mRNA. However, the local translation of PSD-95 mRNA within dendrites and spines, as well as the roles of FMRP or miR-125a, have not been directly studied. Herein, local synthesis of a Venus-PSD-95 fusion protein was directly visualized in dendrites and spines using single-molecule imaging of a diffusion-restricted Venus-PSD-95 reporter under control of the PSD-95 3'UTR. The basal translation rates of Venus-PSD-95 mRNA was increased in cultured hippocampal neurons from Fmr1 KO mice compared with WT neurons, which correlated with a transient elevation of endogenous PSD-95 within dendrites. Following mGluR stimulation with (S)-3,5-dihydroxyphenylglycine, the rate of Venus-PSD-95 mRNA translation increased rapidly in dendrites of WT hippocampal neurons, but not in those of Fmr1 KO neurons or when the binding site of miR125a, previously shown to bind PSD-95 3'UTR, was mutated. This study provides direct support for the hypothesis that local translation within dendrites and spines is dysregulated in FXS. Impairments in the regulated local synthesis of PSD-95, a critical regulator of synaptic structure and function, may affect the spatiotemporal control of PSD-95 levels and affect dendritic spine development and synaptic plasticity in FXS. Copyright © 2015 the authors 0270-6474/15/357116-15$15.00/0.

  6. PSD Camera Based Position and Posture Control of Redundant Robot Considering Contact Motion

    Science.gov (United States)

    Oda, Naoki; Kotani, Kentaro

    The paper describes a position and posture controller design based on the absolute position by external PSD vision sensor for redundant robot manipulator. The redundancy enables a potential capability to avoid obstacle while continuing given end-effector jobs under contact with middle link of manipulator. Under contact motion, the deformation due to joint torsion obtained by comparing internal and external position sensor, is actively suppressed by internal/external position hybrid controller. The selection matrix of hybrid loop is given by the function of the deformation. And the detected deformation is also utilized in the compliant motion controller for passive obstacle avoidance. The validity of the proposed method is verified by several experimental results of 3link planar redundant manipulator.

  7. UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801

    DEFF Research Database (Denmark)

    Andreasen, Jesper T.; Bach, Anders; Gynther, Mikko

    2013-01-01

    Excessive N-Methyl-d-aspartate receptor (NMDAR)-dependent production of nitric oxide (NO) is involved in the development and maintenance of chronic pain states, and is mediated by postsynaptic density protein-95 (PSD-95). By binding to both the NMDAR and neuronal NO synthase (nNOS), PSD-95 mediates...... the NMDAR/PSD-95/nNOS complex by targeting PSD-95, thereby decreasing NO production without interfering with the NMDAR ion channel function. Here, we compared the effects of a dimeric PSD-95 inhibitor, UCCB01-125, and the NMDAR antagonist, MK-801, on mechanical hypersensitivity in the complete Freund......-induced mechanical hypersensitivity 1 and 24 h after treatment. Moreover, UCCB01-125 was found to reverse CFA-induced hypersensitivity when administered 24 h after CFA treatment, an effect lasting for at least 3 days. At the dose reducing hypersensitivity, MK-801 disrupted attention, long-term memory, and motor...

  8. Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function

    DEFF Research Database (Denmark)

    Andreasen, Jesper T; Nasser, Arafat; Caballero-Puntiverio, Maitane

    2016-01-01

    NMDAR antagonism shows analgesic action in humans and animal pain models, but disrupts cognitive and motor functions. NMDAR-dependent NO production requires tethering of the NMDAR to neuronal NO synthase (nNOS) by the postsynaptic density protein-95 (PSD-95). Perturbing the NMDAR/PSD-95/nNOS inte...... in the STFP test. Collectively, UCCB01-144 reversed both CFA and SNI-induced hypersensitivity, but the efficacy in the SNI model was only transient. This suggests that enhanced BBB permeability of PSD-95 inhibitors improves the analgesic action in neuropathic pain states.......NOS interaction has therefore been proposed as an alternative analgesic mechanism. We recently reported that UCCB01-125, a dimeric PSD-95 inhibitor with limited blood-brain-barrier permeability, reduced mechanical hypersensitivity in the complete Freund's adjuvant (CFA) inflammatory pain model, without disrupting...... of neuropathic pain. Potential cognitive effects of UCCB01-144 were examined using the social transmission of food preference (STFP) test and the V-maze test, and motor coordination was assessed with the rotarod test. UCCB01-144 (10mg/kg) reversed CFA-induced mechanical hypersensitivity after 1h, and completely...

  9. Simulations of a PSD Plastic Neutron Collar for Assaying Fresh Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Hausladen, Paul [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Newby, Jason [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); McElroy, Robert Dennis [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-11-01

    The potential performance of a notional active coincidence collar for assaying uranium fuel based on segmented detectors constructed from the new PSD plastic fast organic scintillator with pulse shape discrimination capability was investigated in simulation. Like the International Atomic Energy Agency's present Uranium Neutron Collar for LEU (UNCL), the PSD plastic collar would also function by stimulating fission in the 235U content of the fuel with a moderated 241Am/Li neutron source and detecting instances of induced fission via neutron coincidence counting. In contrast to the moderated detectors of the UNCL, the fast time scale of detection in the scintillator eliminates statistical errors due to accidental coincidences that limit the performance of the UNCL. However, the potential to detect a single neutron multiple times historically has been one of the properties of organic scintillator detectors that has prevented their adoption for international safeguards applications. Consequently, as part of the analysis of simulated data, a method was developed by which true neutron-neutron coincidences can be distinguished from inter-detector scatter that takes advantage of the position and timing resolution of segmented detectors. Then, the performance of the notional simulated coincidence collar was evaluated for assaying a variety of fresh fuels, including some containing burnable poisons and partial defects. In these simulations, particular attention was paid to the analysis of fast mode measurements. In fast mode, a Cd liner is placed inside the collar to shield the fuel from the interrogating source and detector moderators, thereby eliminating the thermal neutron flux that is most sensitive to the presence of burnable poisons that are ubiquitous in modern nuclear fuels. The simulations indicate that the predicted precision of fast mode measurements is similar to what can be achieved by the present UNCL in thermal mode. For example, the

  10. Double-tract reconstruction after laparoscopic proximal gastrectomy using detachable ENDO-PSD.

    Science.gov (United States)

    Aburatani, Tomoki; Kojima, Kazuyuki; Otsuki, Sho; Murase, Hideaki; Okuno, Keisuke; Gokita, Kentaro; Tomii, Chiharu; Tanioka, Toshiro; Inokuchi, Mikito

    2017-04-07

    Proximal gastrectomy (PG) is widely performed in Japan as a function-preserving surgical approach. Since esophagogastrostomy (EG) was associated with increased reflux symptoms and anastomotic strictures, we have chosen double-tract reconstruction (DTR) as the standard reconstruction method since March 2013. In this study, we described a novel method of laparoscopic DTR using detachable ENDO-PSD and compared its 1-year outcome with EG performed formerly in our institution. Patients who underwent laparoscopic PG between May 2005 and July 2014 were retrospectively divided into two groups based on the type of reconstruction and were subsequently analyzed (19 patients in the DTR group and 22 in the EG group). All of them underwent a laparoscopic PG with regional lymph node dissection. In the DTR group, the lower left port site was extended to 4 cm, and an intracorporeal purse-string suture was performed using the detachable ENDO-PSD. The jejunogastrostomy was fashioned on the anterior side of the remnant stomach parallel to the transection line, 2 cm from the cut end. The EG group used the conventional purse-string suture instrument through the 6 cm upper midline mini-laparotomy incision. Patient characteristics, operative data, early operative complications and 1-year postoperative follow-up findings were compared between the two groups. The frequencies of reflux symptoms (10.5 vs. 54.5%, P = 0.003), usage of proton pump inhibitors (31.6 vs. 72.7%, P = 0.008), and anastomotic strictures (0 vs. 27%, P = 0.014) were significantly lower in the DTR group as compared to the EG group. There were no significant differences between the two groups with regard to operation time, blood loss, postoperative hospital stay, postoperative complications, average postoperative/preoperative weight loss ratio, and postoperative/preoperative ratio of biochemical markers (hemoglobin, total protein, albumin, cholesterol). Our results indicate that DTR is a useful reconstruction

  11. Players over the Surface: Unraveling the Role of Exopolysaccharides in Zinc Biosorption by Fluorescent Pseudomonas Strain Psd.

    Science.gov (United States)

    Upadhyay, Anamika; Kochar, Mandira; Rajam, Manchikatla V; Srivastava, Sheela

    2017-01-01

    Fluorescent Pseudomonas strain Psd is a soil isolate, possessing multiple plant growth promoting (PGP) properties and biocontrol potential. In addition, the strain also possesses high Zn2+ biosorption capability. In this study, we have investigated the role exopolysaccharides (EPS) play in Zn2+ biosorption. We have identified that alginates are the prime components contributing to Zn2+ biosorption. Deletion of the alg8 gene, which codes for a sub-unit of alginate polymerase, led to a significant reduction in EPS production by the organism. We have also demonstrated that the increased alginate production in response to Zn2+ exposure leads to improved biofilm formation by the strain. In the alg8 deletion mutant, however, biofilm formation was severely compromised. Further, we have studied the functional implications of Zn2+ biosorption by Pseudomonas strain Psd by demonstrating the effect on the PGP and biocontrol potential of the strain.

  12. G quadruplex RNA structures in PSD-95 mRNA: potential regulators of miR-125a seed binding site accessibility.

    Science.gov (United States)

    Stefanovic, Snezana; Bassell, Gary J; Mihailescu, Mihaela Rita

    2015-01-01

    Fragile X syndrome (FXS) is the most common inherited form of intellectual disability caused by the CGG trinucleotide expansion in the 3'-untranslated region of the FMR1 gene on the X chromosome, that silences the expression of the Fragile X mental retardation protein (FMRP). FMRP has been shown to bind to a G-rich region within the PSD-95 mRNA which encodes for the postsynaptic density protein 95 (PSD-95), and together with the microRNA miR-125a, to play an important role in the reversible inhibition of the PSD-95 mRNA translation in neurons. The loss of FMRP in Fmr1 KO mice disables this translation control in the production of the PSD-95 protein. Interestingly, the miR-125a binding site on PSD-95 mRNA is embedded in the G-rich region bound by FMRP and postulated to adopt one or more G quadruplex structures. In this study, we have used different biophysical techniques to validate and characterize the formation of parallel G quadruplex structures and binding of miR-125a to its complementary sequence located within the 3' UTR of PSD-95 mRNA. Our results indicate that the PSD-95 mRNA G-rich region folds into alternate G quadruplex conformations that coexist in equilibrium. miR-125a forms a stable complex with PSD-95 mRNA, as evident by characteristic Watson-Crick base-pairing that coexists with one of the G quadruplex forms, suggesting a novel mechanism for G quadruplex structures to regulate the access of miR-125a to its binding site. © 2014 Stefanovic et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  13. Beta1-adrenergic receptor-mediated dilation of rat cerebral artery requires Shaker-type KV1 channels on PSD95 scaffold.

    Science.gov (United States)

    Moore, Christopher L; McClenahan, Samantha J; Hanvey, Hillary M; Jang, Dae-Song; Nelson, Piper L; Joseph, Biny K; Rhee, Sung W

    2015-09-01

    Postsynaptic density-95 (PSD95) is a scaffolding protein in cerebral vascular smooth muscle cells (cVSMCs), which binds to Shaker-type K(+) (KV1) channels and facilitates channel opening through phosphorylation by protein kinase A. β1-Adrenergic receptors (β1ARs) also have a binding motif for PSD95. Functional association of β1AR with KV1 channels through PSD95 may represent a novel vasodilator complex in cerebral arteries (CA). We explored whether a β1AR-PSD95-KV1 complex is a determinant of rat CA dilation. RT-PCR and western blots revealed expression of β1AR in CA. Isoproterenol induced a concentration-dependent dilation of isolated, pressurized rat CA that was blocked by the β1AR blocker CGP20712. Cranial window imaging of middle cerebral arterioles in situ showed isoproterenol- and norepinephrine-induced dilation that was blunted by β1AR blockade. Isoproterenol-induced hyperpolarization of cVSMCs in pressurized CA was blocked by CGP20712. Confocal images of cVSMCs immunostained with antibodies against β1AR and PSD95 indicated strong colocalization, and PSD95 co-immunoprecipitated with β1AR in CA lysate. Blockade of KV1 channels, β1AR or disruption of PSD95-KV1 interaction produced similar blunting of isoproterenol-induced dilation in pressurized CA. These findings suggest that PSD95 mediates a vasodilator complex with β1AR and KV1 channels in cVSMCs. This complex may be critical for proper vasodilation in rat CA.

  14. Production of the active antifungal Pisum sativum defensin 1 (Psd1) in Pichia pastoris: overcoming the inefficiency of the STE13 protease.

    Science.gov (United States)

    Cabral, Kátia M S; Almeida, Marcius S; Valente, Ana Paula; Almeida, Fábio C L; Kurtenbach, Eleonora

    2003-09-01

    Plant defensins are small cysteine-rich proteins that present high activity against fungi and bacteria and inhibition of insect proteases and alpha-amylases. Here, we present the expression in Pichia pastoris, purification and characterization of the recombinant Pisum sativum defensin 1(rPsd1); a pea defensin which presents four disulfide bridges and high antifungal activity. For this, we had to overcome the inefficiency of the STE13 protease. Our strategy was to clone the corresponding cDNA directly in-frame with a variant of the widely used secretion signal from the Saccharomyces cerevisiae alpha-mating factor, devoid of the STE13 proteolytic signal cleavage sequence. Using an optimized expression protocol, which included a buffered basal salt media formulation, it was possible to obtain about 63.0mg/L of 15N-labeled and unlabeled rPsd1. The recombinants were purified to homogeneity by gel filtration chromatography, followed by reversed-phase HPLC. Mass spectrometry of native and recombinant Psd1 revealed that the protein expressed heterologously was post-translationally processed to the same mature protein as the native one. Circular dichroism and nuclear magnetic resonance spectroscopy analysis indicated that the recombinant protein had the same folding when compared to native Psd1. In addition, the rPsd1 was fully active against Aspergillus niger, if compared with native Psd1. To our knowledge, this is the first heterologous expression of a fully active plant defensin in a high-yield flask.

  15. DA Negatively Regulates IGF-I Actions Implicated in Cognitive Function via Interaction of PSD95 and nNOS in Minimal Hepatic Encephalopathy

    Directory of Open Access Journals (Sweden)

    Saidan Ding

    2017-09-01

    Full Text Available Insulin-like growth factor I (IGF-I has been positively correlated with cognitive ability. Cognitive decline in minimal hepatic encephalopathy (MHE was shown to be induced by elevated intracranial dopamine (DA. The beneficial effect of IGF-I signaling in MHE remains unknown. In this study, we found that IGF-I content was reduced in MHE rats and that IGF-I administration mitigated cognitive decline of MHE rats. A protective effect of IGF-I on the DA-induced interaction between postsynaptic density protein 95 (PSD95 and neuronal nitric oxide synthase (nNOS was found in neurons. Ribosomal S6 protein kinase (RSK phosphorylated nNOS in response to IGF-I by recruiting extracellular signal-regulated kinase (ERK1/2. In turn, DA inactivated the ERK1/2/RSK pathway and stimulated the PSD95–nNOS interaction by downregulating IGF-I. Inhibition of the interaction between PSD95 and nNOS ameliorated DA-induced memory impairment. As DA induced deficits in the ERK1/2/RSK pathway and the interaction between PSD95 and nNOS in MHE brains, IGF-I administration exerted a protective effect via interruption of the interaction between PSD95 and nNOS. These results suggest that IGF-I antagonizes DA-induced cognitive loss by disrupting PSD95–nNOS interactions in MHE.

  16. Preparation of a continuative brochure as supplement to the evaluation hand-out for the assessment of study results; Erstellung einer weiterfuehrenden Broschuere als Ergaenzung zur Handreichung der Beurteilung von Studienergebnissen

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelmy, S.; Gollnick, F.; Driessen, S.; Schmidt, M.; Gross, D.

    2015-08-15

    In 2013 the Federal Office for Radiation Protection gave the responsibility to the Department of History, Philosophy and Ethics of Medicine (Institut GTE Med) in Aachen for the project ''Creating a practical hand-out for the assessment of study results for employees of local governments'' (FM 8855). The manual serves as a practical way for the qualitative evaluation of texts for persons who deal with the topics Mobile Communication and Health (for example communities or government agencies) in their profession. The main objective of the manual is to aid users in performing a faster and more efficient evaluation of texts by answering the containing questions. This approach is purely functional and precludes the placement of deeper information. At this point the new project FM 8862 started by ''Creating a continuative brochure in addition to the hand-out for the assessment of study results''. It continued the previous project FM 8855 to further develop the information which was up to this point purely functional. The brochure presents the issues in an overall context and provides valuable background knowledge. As a result, possible users get in a more casual and clear manner a deeper understanding of the evaluating of texts. It should be possible for a user to better evaluate texts and by obtaining arguments, thus being better prepared to engage with interested Laymen in an objective discussion. The brochure was submitted together with the existing manual for a practical test, which was attended by 21 target group-specific subjects. The study tested in detail the intelligibility, clarity, applicability, and the support of the brochure. The feedback of the test participants were then used as basis for the final optimization of the brochure. Project participants belong to the Department of History, Philosophy and Ethics of Medicine and the Research Center for Bioelectromagnetic Interaction of the RWTH Aachen University (femu).

  17. Decrease in neuronal nicotinic acetylcholine receptor subunit and PSD-93 transcript levels in the male mouse MPG after cavernous nerve injury or explant culture

    Science.gov (United States)

    Girard, Beatrice M.; Merriam, Laura A.; Tompkins, John D.; Vizzard, Margaret A.

    2013-01-01

    Quantitative real-time PCR was used to test whether cavernous nerve injury leads to a decrease in major pelvic ganglia (MPG) neuronal nicotinic ACh receptor (nAChR) subunit and postsynaptic density (PSD)-93 transcript levels. Subunits α3, β4, and α7, commonly expressed in the MPG, were selected for analysis. After 72 h in explant culture, MPG transcript levels for α3, β4, α7, and PSD-93 were significantly depressed. Three days after cavernous nerve axotomy or crush in vivo, transcript levels for α3, β4, and PSD-93, but not for α7, were significantly depressed. Three days after dissection of the cavernous nerve free of underlying tissue and application of a 5-mm lateral stretch (manipulation), transcript levels for α3 and PSD-93 were also significantly decreased. Seven days after all three surgical procedures, α3 transcript levels remained depressed, but PSD-93 transcript levels were still decreased only after axotomy or nerve crush. At 30 days postsurgery, transcript levels for the nAChR subunits and PSD-93 had recovered. ACh-induced currents were significantly smaller in MPG neurons dissociated from 3-day explant cultured ganglia than from those recorded in neurons dissociated from acutely isolated ganglia; this observation provides direct evidence showing that a decrease in nAChR function was coincident with a decrease in nAChR subunit transcript levels. We conclude that a downregulation of nAChR subunit and PSD-93 expression after cavernous nerve injury, or even manipulation, could interrupt synaptic transmission within the MPG and thus contribute to the loss of neural control of urogenital organs after pelvic surgeries. PMID:24049141

  18. Response to Request for Guidance on PSD Definition Referencing Cogeneration Gas Turbines that are Separated by One-Half Mile

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  19. Determination of the Applicability of NSPS and PSD to Stationary Gas Turbines Converting From Middle Distillates to Natural Gas

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  20. Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats

    DEFF Research Database (Denmark)

    Sommer, Jens Bak; Bach, Anders; Rytter, Hana Malá

    2017-01-01

    be an effective therapeutic strategy in TBI. The objectives of the present study were to assess the effects of a dimeric inhibitor of PSD-95, UCCB01-144, on excitotoxic cell death in vitro and outcome after experimental TBI in rats in vivo. In addition, the pharmacokinetic parameters of UCCB01-144 were...... assessed in a water maze at two weeks post-trauma, and at four weeks lesion volumes were estimated. Overall, UCCB01-144 did not protect against NMDA-toxicity in neuronal cultures or experimental TBI in rats. Important factors that should be investigated further in future studies assessing the effects...

  1. PSD Applicability Analysis for a Past Change at the Georgia-Pacific Taylorsville Facility Particleboard Plant, Taylorsville, Mississippi

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  2. Indoor Positioning System Based on a PSD Detector, Precise Positioning of Agents in Motion Using AoA Techniques.

    Science.gov (United States)

    Rodríguez-Navarro, David; Lázaro-Galilea, José Luis; De-La-Llana-Calvo, Álvaro; Bravo-Muñoz, Ignacio; Gardel-Vicente, Alfredo; Tsirigotis, Georgios; Iglesias-Miguel, Juan

    2017-09-15

    Here, we present an indoor positioning system (IPS) for detecting mobile agents based on a single Position Sensitive Device sensor (PSD) sited in the environment and InfraRed Emitter Diode (IRED) located on mobile agents. The main goal of the work is to develop an alternative IPS to other sensing technologies, cheaper, easier to install and with a low computational load to obtain a high rate of measurements per second. The proposed IPS has the capacity to accurately determine 3D position from the angle of arrival (AoA) of the signal received at the PSD sensor. In this first approach to the method, the agents are considered to move along a plane. We propose two alternatives for determining position: in one, tones are emitted on a frequency unique to each transmitter, while in the other, sequences are emitted.The paper proposes and set up a very simple and easy to deploy system capable of performing 3D positioning with a single analog sensor, obtaining a high accurate positioning and a reduced execution time for the signal processing. The low computational load of the IPS makes it possible to obtain a very high position update rate (more than 100 times per second), yielding millimetric accuracies.

  3. Technology for NASA's Planetary Science Vision 2050.

    Science.gov (United States)

    Lakew, B.; Amato, D.; Freeman, A.; Falker, J.; Turtle, Elizabeth; Green, J.; Mackwell, S.; Daou, D.

    2017-01-01

    NASAs Planetary Science Division (PSD) initiated and sponsored a very successful community Workshop held from Feb. 27 to Mar. 1, 2017 at NASA Headquarters. The purpose of the Workshop was to develop a vision of planetary science research and exploration for the next three decades until 2050. This abstract summarizes some of the salient technology needs discussed during the three-day workshop and at a technology panel on the final day. It is not meant to be a final report on technology to achieve the science vision for 2050.

  4. Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions

    DEFF Research Database (Denmark)

    Bach, Anders

    2015-01-01

    ZL006 and IC87201 have been presented as efficient inhibitors of the nNOS/PSD-95 protein-protein interaction and shown great promise in cellular experiments and animal models of ischemic stroke and pain. Here, we investigate the proposed mechanism of action of ZL006 and IC87201 using biochemical...... and biophysical methods, such as fluorescence polarization (FP), isothermal titration calorimetry (ITC), and (1)H-(15)N HSQC NMR. Our data show that under the applied in vitro conditions, ZL006 and IC87201 do not interact with the PDZ domains of nNOS or PSD-95, nor inhibit the nNOS-PDZ/PSD-95-PDZ interface...... by interacting with the β-finger of nNOS-PDZ. Our findings have implications for further medicinal chemistry efforts of ZL006, IC87201 and analogues, and challenge the general and widespread view on their mechanism of action....

  5. Investigation of the Deposition and Densification Parameters on the Mechanical Properties of Pressurized Spray Deposited (PSD) 3-D Printed Ceramic Components

    Energy Technology Data Exchange (ETDEWEB)

    Menchhofer, Paul A [ORNL; Becker, Benjamin [Hot End Works

    2016-07-28

    Oak Ridge National Laboratory (ORNL) and HotEnd Works teamed to investigate the use of pressurized spray deposition (PSD) technology for the production of ceramic parts via additive manufacturing. Scanning electron microscopy of sintered parts provided by HotEnd Works revealed voids large enough to compromise the mechanical properties of PSD manufactured parts. Scanning electron microscopy and particle size analysis of the alumina oxide powder feedstocks indicated that the powders contained some large particles and some agglomerations in the powder. Further classification of the powder feedstocks and removal of the agglomerates by sonication in the liquid used for the PSD process are recommended. Analysis of sintered parts indicated that the sonic modulus for the alumina part is consistent with other known values for alumina. The density for this part was determined by standard Archimedes immersion density methods and was found to be > 99.7 % of the theoretical density for pure alumina.

  6. "Here, There, and Everywhere": Connecting Science Across The Universe

    Science.gov (United States)

    Watzke, Megan; Slane, P. O.; Arcand, K. K.; Lestition, K.; Edmonds, P.; Tucker, W. H.

    2013-04-01

    "Here, There, and Everywhere" (HTE) is a program -- conceived and developed by the Chandra Education and Public Outreach group -- that consists of a series of exhibitions, posters, and supporting hands-on activities that utilize analogies in the teaching of science, engineering, and technology to provide multi-generational and family-friendly content in English and Spanish to small community centers, libraries, under-resourced small science centers. The purpose of the program is to connect crosscutting science content (in Earth, atmospheric and planetary sciences and astrophysics) with everyday phenomena, helping to demonstrate the universality of physical laws and the connection between our everyday world and the universe as a whole to members of the public who may not identify strongly with science. The program utilizes multimodal content delivery (physical exhibits and handouts, interpretive stations, facilitated activities for educators as well as online materials) hosted by under-served locations as identified by previous partnerships as well as through advertisement of opportunities.

  7. PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.

    Directory of Open Access Journals (Sweden)

    Fernando J Bustos

    Full Text Available Considerable evidence indicates that the NMDA receptor (NMDAR subunits NR2A and NR2B are critical mediators of synaptic plasticity and dendritogenesis; however, how they differentially regulate these processes is unclear. Here we investigate the roles of the NR2A and NR2B subunits, and of their scaffolding proteins PSD-95 and SAP102, in remodeling the dendritic architecture of developing hippocampal neurons (2-25 DIV. Analysis of the dendritic architecture and the temporal and spatial expression patterns of the NMDARs and anchoring proteins in immature cultures revealed a strong positive correlation between synaptic expression of the NR2B subunit and dendritogenesis. With maturation, the pruning of dendritic branches was paralleled by a strong reduction in overall and synaptic expression of NR2B, and a significant elevation in synaptic expression of NR2A and PSD95. Using constructs that alter the synaptic composition, we found that either over-expression of NR2B or knock-down of PSD95 by shRNA-PSD95 augmented dendritogenesis in immature neurons. Reactivation of dendritogenesis could also be achieved in mature cultured neurons, but required both manipulations simultaneously, and was accompanied by increased dendritic clustering of NR2B. Our results indicate that the developmental increase in synaptic expression of PSD95 obstructs the synaptic clustering of NR2B-NMDARs, and thereby restricts reactivation of dendritic branching. Experiments with shRNA-PSD95 and chimeric NR2A/NR2B constructs further revealed that C-terminus of the NR2B subunit (tail was sufficient to induce robust dendritic branching in mature hippocampal neurons, and suggest that the NR2B tail is important in recruiting calcium-dependent signaling proteins and scaffolding proteins necessary for dendritogenesis.

  8. p-sd Shell Gap Reduction in Neutron-Rich Systems and Cross-ShellExcitations in 20O

    Energy Technology Data Exchange (ETDEWEB)

    Wiedeking, M.; Tabor, S.L.; Pavan, J.; Volya, A.; Aguilar, A.L.; Calderin, I.J.; Campbell, D.B.; Cluff, W.T.; Diffenderfer, E.; Fridmann,J.; Hoffman, C.R.; Kemper, K.W.; Lee, S.; Riley, M.A.; Roeder, B.T.; Teal, C.; Tripathi, V.; Wiedenhover, I.

    2005-04-07

    Excited states in {sup 20}O were populated in the reaction {sup 10}Be({sup 14}C,{alpha}) at Florida State University (FSU). Charged particles were detected with a particle telescope consisting of 4 annularly segmented Si surface barrier detectors and {gamma} radiation was detected with the FSU {gamma} detector array. Five new states were observed below 6 MeV from the {alpha}-{gamma} and {alpha}-{gamma}-{gamma} coincidence data. Shell model calculations suggest that most of the newly observed states are core-excited 1p-1h excitations across the N=Z=8 shell gap. Comparisons between experimental data and calculations for the neutron-rich O and F isotopes imply a steady reduction of the p-sd shell gap as neutrons are added.

  9. FRET-FLIM investigation of PSD95-NMDA receptor interaction in dendritic spines; control by calpain, CaMKII and Src family kinase.

    Directory of Open Access Journals (Sweden)

    Kim Doré

    Full Text Available Little is known about the changes in protein interactions inside synapses during synaptic remodeling, as their live monitoring in spines has been limited. We used a FRET-FLIM approach in developing cultured rat hippocampal neurons expressing fluorescently tagged NMDA receptor (NMDAR and PSD95, two essential proteins in synaptic plasticity, to examine the regulation of their interaction. NMDAR stimulation caused a transient decrease in FRET between the NMDAR and PSD95 in spines of young and mature neurons. The activity of both CaMKII and calpain were essential for this effect in both developmental stages. Meanwhile, inhibition of Src family kinase (SFK had opposing impacts on this decrease in FRET in young versus mature neurons. Our data suggest concerted roles for CaMKII, SFK and calpain activity in regulating activity-dependent separation of PSD95 from GluN2A or GluN2B. Finally, we found that calpain inhibition reduced spine growth that was caused by NMDAR activity, supporting the hypothesis that PSD95-NMDAR separation is implicated in synaptic remodeling.

  10. A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    DEFF Research Database (Denmark)

    Bach, Anders*; Clausen, Bettina H; Møller, Magda

    2012-01-01

    Inhibition of the ternary protein complex of the synaptic scaffolding protein postsynaptic density protein-95 (PSD-95), neuronal nitric oxide synthase (nNOS), and the N-methyl-d-aspartate (NMDA) receptor is a potential strategy for treating ischemic brain damage, but high-affinity inhibitors...

  11. Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment.

    Science.gov (United States)

    Whitfield, David R; Vallortigara, Julie; Alghamdi, Amani; Howlett, David; Hortobágyi, Tibor; Johnson, Mary; Attems, Johannes; Newhouse, Stephen; Ballard, Clive; Thomas, Alan J; O'Brien, John T; Aarsland, Dag; Francis, Paul T

    2014-12-01

    The loss of zinc transporter 3 (ZnT3) has been implicated in age-related cognitive decline in mice, and the protein has been associated with plaques. We investigated the levels of ZnT3 and postsynaptic density protein 95 (PSD95), a marker of the postsynaptic terminal, in people with Parkinson's disease dementia (PDD, n = 31), dementia with Lewy bodies (DLB, n = 44), Alzheimer's disease (AD, n = 16), and controls (n = 24), using semiquantitative western blotting and immunohistochemistry in 3 cortical regions. Standardized cognitive assessments during life and semiquantitative scoring of amyloid β (Aβ), tau, and α-synuclein at postmortem were used to investigate the relationship between ZnT3 and PSD95, cognition and pathology. Associations were observed between ZnT3 and PSD95 levels in prefrontal cortex and cognitive impairment (p = 0.001 and p = 0.002, respectively) and between ZnT3 levels in the parietal cortex and cognitive impairment (p = 0.036). Associations were also seen between ZnT3 levels in cingulate cortex and severity of Aβ (p = 0.003) and tau (p = 0.011) pathologies. DLB and PDD were characterized by significant reductions of PSD95 (p < 0.05) and ZnT3 (p < 0.001) in prefrontal cortex compared with controls and AD. PSD95 levels in the parietal cortex were found to be decreased in AD cases compared with controls (p = 0.02) and PDD (p = 0.005). This study has identified Zn(2+) modulation as a possible novel target for the treatment of cognitive impairment in DLB and PDD and the potential for synaptic proteins to be used as a biomarker for the differentiation of DLB and PDD from AD. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. HERE, THERE, AND EVERYWHEREPublic Science Through Analogy

    Science.gov (United States)

    Arcand, Kimberly K.

    2014-06-01

    Here, There, and Everywhere (HTE) is a program that consists of a series of exhibitions, posters, and supporting hands-on activities that utilize analogies in the teaching of science, engineering, and technology to provide multi-generational and family-friendly content in English and Spanish to small community centers, libraries, under-resourced small science centers. The purpose of the program is to connect crosscutting science content (in Earth, atmospheric and planetary sciences and astrophysics) with everyday phenomena. By using different modes of content delivery, from physical exhibits and handouts,to interpretive stations, facilitated activities for educators, and online resources, HTE helps to demonstrate the universality of physical laws and the connection between our everyday world and the universe as a whole to members of the public who may not identify strongly with science. HTE is part of a series of public science projects created and developed by the Education and Public Outreach group at the Chandra X-ray Center. The authors discuss how HTE fits into the lineage of public science outreach that aims to engage the greater public in non-traditional venues for science learning and appreciation, as well as what might be learned about the participants of such projects.

  13. The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions.

    Science.gov (United States)

    Belotti, Edwige; Polanowska, Jolanta; Daulat, Avais M; Audebert, Stéphane; Thomé, Virginie; Lissitzky, Jean-Claude; Lembo, Frédérique; Blibek, Karim; Omi, Shizue; Lenfant, Nicolas; Gangar, Akanksha; Montcouquiol, Mireille; Santoni, Marie-Josée; Sebbagh, Michael; Aurrand-Lions, Michel; Angers, Stéphane; Kodjabachian, Laurent; Reboul, Jérome; Borg, Jean-Paul

    2013-09-01

    Protein-protein interactions organize the localization, clustering, signal transduction, and degradation of cellular proteins and are therefore implicated in numerous biological functions. These interactions are mediated by specialized domains able to bind to modified or unmodified peptides present in binding partners. Among the most broadly distributed protein interaction domains, PSD95-disc large-zonula occludens (PDZ) domains are usually able to bind carboxy-terminal sequences of their partners. In an effort to accelerate the discovery of PDZ domain interactions, we have constructed an array displaying 96% of the human PDZ domains that is amenable to rapid two-hybrid screens in yeast. We have demonstrated that this array can efficiently identify interactions using carboxy-terminal sequences of PDZ domain binders such as the E6 oncoviral protein and protein kinases (PDGFRβ, BRSK2, PCTK1, ACVR2B, and HER4); this has been validated via mass spectrometry analysis. Taking advantage of this array, we show that PDZ domains of Scrib and SNX27 bind to the carboxy-terminal region of the planar cell polarity receptor Vangl2. We also have demonstrated the requirement of Scrib for the promigratory function of Vangl2 and described the morphogenetic function of SNX27 in the early Xenopus embryo. The resource presented here is thus adapted for the screen of PDZ interactors and, furthermore, should facilitate the understanding of PDZ-mediated functions.

  14. In vitro and in vivo effects of a novel dimeric inhibitor of PSD-95 on excitotoxicity and functional recovery after experimental traumatic brain injury

    DEFF Research Database (Denmark)

    Sommer, Jens Bak; Bach, Anders; Rytter, Hana Malá

    2017-01-01

    PSD-95 inhibitors have been shown to be neuroprotective in stroke, but have only to a very limited extent been evaluated in the treatment of traumatic brain injury (TBI) that has pathophysiological mechanisms in common with stroke. The aims of the current study were to assess the effects of a nov...... studies taking important experimental factors such as timing of treatment, dosage, and anesthesia into consideration....

  15. Technology needs identified at NASA's Planetary Science Vision 2050 workshop

    Science.gov (United States)

    Lakew, B.; Amato, D.; Freeman, A.; Falker, J.; Turtle, E.; Green, J.; Mackwell, S.; Daou, D.

    2017-09-01

    NASA's Planetary Science Division (PSD) initiated and sponsored a very successful community Workshop held from Feb. 27 to Mar. 1, 2017 at NASA Headquarters. The purpose of the Workshop was to develop a vision of planetary science research and exploration for the next three decades until 2050. This abstract summarizes some of the salient technology needs discussed during the three-day workshop and at a technology panel on the final day. It is not meant to be a final report on technology to achieve the science vision for 2050.

  16. High Dynamics and Precision Optical Measurement Using a Position Sensitive Detector (PSD in Reflection-Mode: Application to 2D Object Tracking over a Smart Surface

    Directory of Open Access Journals (Sweden)

    Ioan Alexandru Ivan

    2012-12-01

    Full Text Available When related to a single and good contrast object or a laser spot, position sensing, or sensitive, detectors (PSDs have a series of advantages over the classical camera sensors, including a good positioning accuracy for a fast response time and very simple signal conditioning circuits. To test the performance of this kind of sensor for microrobotics, we have made a comparative analysis between a precise but slow video camera and a custom-made fast PSD system applied to the tracking of a diffuse-reflectivity object transported by a pneumatic microconveyor called Smart-Surface. Until now, the fast system dynamics prevented the full control of the smart surface by visual servoing, unless using a very expensive high frame rate camera. We have built and tested a custom and low cost PSD-based embedded circuit, optically connected with a camera to a single objective by means of a beam splitter. A stroboscopic light source enhanced the resolution. The obtained results showed a good linearity and a fast (over 500 frames per second response time which will enable future closed-loop control by using PSD.

  17. A Specific Nutrient Combination Attenuates the Reduced Expression of PSD-95 in the Proximal Dendrites of Hippocampal Cell Body Layers in a Mouse Model of Phenylketonuria

    Science.gov (United States)

    Bruinenberg, Vibeke M.; van Vliet, Danique; Attali, Amos; de Wilde, Martijn C.; Kuhn, Mirjam; van Spronsen, Francjan J.; van der Zee, Eddy A.

    2016-01-01

    The inherited metabolic disease phenylketonuria (PKU) is characterized by increased concentrations of phenylalanine in the blood and brain, and as a consequence neurotransmitter metabolism, white matter, and synapse functioning are affected. A specific nutrient combination (SNC) has been shown to improve synapse formation, morphology and function. This could become an interesting new nutritional approach for PKU. To assess whether treatment with SNC can affect synapses, we treated PKU mice with SNC or an isocaloric control diet and wild-type (WT) mice with an isocaloric control for 12 weeks, starting at postnatal day 31. Immunostaining for post-synaptic density protein 95 (PSD-95), a post-synaptic density marker, was carried out in the hippocampus, striatum and prefrontal cortex. Compared to WT mice on normal chow without SNC, PKU mice on the isocaloric control showed a significant reduction in PSD-95 expression in the hippocampus, specifically in the granular cell layer of the dentate gyrus, with a similar trend seen in the cornus ammonis 1 (CA1) and cornus ammonis 3 (CA3) pyramidal cell layer. No differences were found in the striatum or prefrontal cortex. PKU mice on a diet supplemented with SNC showed improved expression of PSD-95 in the hippocampus. This study gives the first indication that SNC supplementation has a positive effect on hippocampal synaptic deficits in PKU mice. PMID:27102170

  18. Writing Like a Scientist: Exploring Elementary Teachers' Understandings and Practices of Writing in Science

    Science.gov (United States)

    Glen, Nicole J.; Dotger, Sharon

    2013-10-01

    This qualitative study examined the connections between elementary teachers’ conceptions of how scientists use writing and how the teachers used writing during science lessons. Data collected included lesson observations, interviews, handouts to students, and curriculum resources. The findings revealed that teachers in this study thought scientists write for several purposes: the presentation of data, observations, experiences, procedures, and facts. The teachers used writing tasks that mirrored this with their students. The teachers also had a limited definition of creativity in writing, and when they had students write creatively in science it was to add in fictional elements. Implications of this study include providing teachers with better models for how and why scientists write, including these models in more inquiry-based science lessons, and directly relating concepts of nature of science to elementary science writing.

  19. Planetary Science Technology Infusion Study: Findings and Recommendations Status

    Science.gov (United States)

    Anderson, David J.; Sandifer, Carl E., II; Sarver-Verhey, Timothy R.; Vento, Daniel M.; Zakrajsek, June F.

    2014-01-01

    The Planetary Science Division (PSD) within the National Aeronautics and Space Administrations (NASA) Science Mission Directorate (SMD) at NASA Headquarters sought to understand how to better realize a scientific return on spacecraft system technology investments currently being funded. In order to achieve this objective, a team at NASA Glenn Research Center was tasked with surveying the science and mission communities to collect their insight on technology infusion and additionally sought inputs from industry, universities, and other organizations involved with proposing for future PSD missions. This survey was undertaken by issuing a Request for Information (RFI) activity that requested input from the proposing community on present technology infusion efforts. The Technology Infusion Study was initiated in March 2013 with the release of the RFI request. The evaluation team compiled and assessed this input in order to provide PSD with recommendations on how to effectively infuse new spacecraft systems technologies that it develops into future competed missions enabling increased scientific discoveries, lower mission cost, or both. This team is comprised of personnel from the Radioisotope Power Systems (RPS) Program and the In-Space Propulsion Technology (ISPT) Program staff.The RFI survey covered two aspects of technology infusion: 1) General Insight, including: their assessment of barriers to technology infusion as related to infusion approach; technology readiness; information and documentation products; communication; integration considerations; interaction with technology development areas; cost-capped mission areas; risk considerations; system level impacts and implementation; and mission pull. 2) Specific technologies from the most recent PSD Announcements of Opportunities (AOs): The Advanced Stirling Radioisotope Generator (ASRG), aerocapture and aeroshell hardware technologies, the NASA Evolutionary Xenon Thruster (NEXT) ion propulsion system, and the

  20. Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders

    Directory of Open Access Journals (Sweden)

    Annalisa Alfieri

    2017-06-01

    Full Text Available Altered synaptic function has been associated with neurological and psychiatric conditions including intellectual disability, schizophrenia and autism spectrum disorder (ASD. Amongst the recently discovered synaptic proteins is p140Cap, an adaptor that localizes at dendritic spines and regulates their maturation and physiology. We recently showed that p140Cap knockout mice have cognitive deficits, impaired long-term potentiation (LTP and long-term depression (LTD, and immature, filopodia-like dendritic spines. Only a few p140Cap interacting proteins have been identified in the brain and the molecular complexes and pathways underlying p140Cap synaptic function are largely unknown. Here, we isolated and characterized the p140Cap synaptic interactome by co-immunoprecipitation from crude mouse synaptosomes, followed by mass spectrometry-based proteomics. We identified 351 p140Cap interactors and found that they cluster to sub complexes mostly located in the postsynaptic density (PSD. p140Cap interactors converge on key synaptic processes, including transmission across chemical synapses, actin cytoskeleton remodeling and cell-cell junction organization. Gene co-expression data further support convergent functions: the p140Cap interactors are tightly co-expressed with each other and with p140Cap. Importantly, the p140Cap interactome and its co-expression network show strong enrichment in genes associated with schizophrenia, autism, bipolar disorder, intellectual disability and epilepsy, supporting synaptic dysfunction as a shared biological feature in brain diseases. Overall, our data provide novel insights into the molecular organization of the synapse and indicate that p140Cap acts as a hub for postsynaptic complexes relevant to psychiatric and neurological disorders.

  1. Guidance, Navigation, and Control Technology Assessment for Future Planetary Science Missions

    Science.gov (United States)

    Beauchamp, Pat; Cutts, James; Quadrelli, Marco B.; Wood, Lincoln J.; Riedel, Joseph E.; McHenry, Mike; Aung, MiMi; Cangahuala, Laureano A.; Volpe, Rich

    2013-01-01

    Future planetary explorations envisioned by the National Research Council's (NRC's) report titled Vision and Voyages for Planetary Science in the Decade 2013-2022, developed for NASA Science Mission Directorate (SMD) Planetary Science Division (PSD), seek to reach targets of broad scientific interest across the solar system. This goal requires new capabilities such as innovative interplanetary trajectories, precision landing, operation in close proximity to targets, precision pointing, multiple collaborating spacecraft, multiple target tours, and advanced robotic surface exploration. Advancements in Guidance, Navigation, and Control (GN&C) and Mission Design in the areas of software, algorithm development and sensors will be necessary to accomplish these future missions. This paper summarizes the key GN&C and mission design capabilities and technologies needed for future missions pursuing SMD PSD's scientific goals.

  2. Binaural noise reduction via cue-preserving MMSE filter and adaptive-blocking-based noise PSD estimation

    Science.gov (United States)

    Azarpour, Masoumeh; Enzner, Gerald

    2017-12-01

    Binaural noise reduction, with applications for instance in hearing aids, has been a very significant challenge. This task relates to the optimal utilization of the available microphone signals for the estimation of the ambient noise characteristics and for the optimal filtering algorithm to separate the desired speech from the noise. The additional requirements of low computational complexity and low latency further complicate the design. A particular challenge results from the desired reconstruction of binaural speech input with spatial cue preservation. The latter essentially diminishes the utility of multiple-input/single-output filter-and-sum techniques such as beamforming. In this paper, we propose a comprehensive and effective signal processing configuration with which most of the aforementioned criteria can be met suitably. This relates especially to the requirement of efficient online adaptive processing for noise estimation and optimal filtering while preserving the binaural cues. Regarding noise estimation, we consider three different architectures: interaural (ITF), cross-relation (CR), and principal-component (PCA) target blocking. An objective comparison with two other noise PSD estimation algorithms demonstrates the superiority of the blocking-based noise estimators, especially the CR-based and ITF-based blocking architectures. Moreover, we present a new noise reduction filter based on minimum mean-square error (MMSE), which belongs to the class of common gain filters, hence being rigorous in terms of spatial cue preservation but also efficient and competitive for the acoustic noise reduction task. A formal real-time subjective listening test procedure is also developed in this paper. The proposed listening test enables a real-time assessment of the proposed computationally efficient noise reduction algorithms in a realistic acoustic environment, e.g., considering time-varying room impulse responses and the Lombard effect. The listening test outcome

  3. [Effects of electroacupuncture at different acupoints on learning and memory ability and PSD-95 protein expression on hippocampus CA1 in rats with autism].

    Science.gov (United States)

    Zhang, Xue-Jun; Wu, Qiang

    2013-07-01

    To explore the effect mechanism of electroacupuncture (EA) at Changqiang (GV 1) or Baihui (GV 20) on autism based on molecular biology. The autism model was established by intraperitoneal injection of sodium valproate (VPA) in Wistar pregnant rats. Forty young rats with autism were selected and randomly divided into a model group, a non-acupoint group, an electroacupuncture at "Changqiang" (GV 1) (EAGV 1 for short) group and an electroacupuncture at "Baihui" (GV 20) (EAGV 20 for short) group. Another 10 normal young rats were selected as a blank group. In the EAGV 1 group, acupuncture was applied at Houhai [as Changqiang (GV 1)], then EA apparatus was connected with continuous wave, 2 Hz, 20 min, once a day for consecutive 20 days. The same EA manipulation as EAGV 1 group was used in the EAGV 20 group where "Baihui" (GV 20) was selected and non-acupoint group where non-acupoint in the right rib was selected. Blank group and model group were reared under the same conditions without any intervention. The escape latency and the ratio of swimming distance in platform quadrant to total swimming distance in each group were observed by using Morris water maze, and the PSD-95 protein expression in hippocampal CA 1 was measured by immunohistochemical techniques. Compared with the blank group, the escape latency in the model group and the non-acupoint group lengthened (both P swimming distance in platform quadrant to total swimming distance was decreased (both P swimming distance in platform quadrant to total swimming distance was increased, the PSD-95 protein expression was increased (both P swimming distance in platform quadrant to total swimming distance and the PSD-95 protein expression had no significant difference between EAGV 1 group and EAGV 20 group (P > 0.05). Electroacupuncture at Changqiang (GV 1) or Baihui (GV 20) can respectively improve learning and memory ability of rats with autism, which has no significant difference and the mechanism of action may be

  4. Employment of Molecularly Imprinted Polymers to High-Throughput Screen nNOS-PSD-95 Interruptions: Structure and Dynamics Investigations on Monomer-Template Complexation.

    Science.gov (United States)

    Wang, Yongwei; Zhao, Ting; Dai, Peng; Jiang, Nan; Li, Fei

    2016-03-16

    Molecularly imprinted polymers (MIPs) are employed to screen nNOS-PSD-95 (neuronal nitric oxide synthase post-synaptic density protein-95) interruptions. 5-(3,5-Dichloro-2-hydroxybenzylamino)-2-hydroxybenzoic acid (ZL006; a potential drug candidate for the treatment of stroke, depression, and pain) is employed as a template. Four kinds of functional monomers (2-VP: 2-vinylpyridine; 4-VP: 4-vinylpyridine; MMA: methyl methacrylate; and MAAM: methacrylamide) are designed, and their complexation with ZL006 in various solvents (methanol, acetonitrile, toluene, chloroform) is investigated by molecular dynamics simulations and quantum mechanics calculations. Both 4-VP and MAAM have stronger interactions with ZL006 than those of 2-VP and MMA. The appropriate ratio of monomer to template is 3:1. Intermolecular hydrogen bonds play a dominant role in monomer-template complexation. Ideal solvents are toluene and chloroform, and the solvation effect on monomer-template complexation is revealed. Both molecular modeling and adsorption experiments demonstrate that as-synthesized ZL006-MIP with 4-VP as a monomer has better selectivity than that employing MAAM to screen for nNOS-PSD-95 interruptions. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Science and Science Fiction

    Science.gov (United States)

    Oravetz, David

    2005-01-01

    This article is for teachers looking for new ways to motivate students, increase science comprehension, and understanding without using the old standard expository science textbook. This author suggests reading a science fiction novel in the science classroom as a way to engage students in learning. Using science fiction literature and language…

  6. Science for Kids Outreach Programs: College Students Teaching Science to Elementary Students and Their Parents

    Science.gov (United States)

    Koehler, Birgit G.; Park, Lee Y.; Kaplan, Lawrence J.

    1999-11-01

    For a number of years we have been organizing and teaching a special outreach course during our Winter Study Program (the month of January). College students plan, develop, and present hands-on workshops to fourth-grade students and their parents, with faculty providing logistical support and pedagogical advice. Recent topics have been "Forensic Science", "Electricity and Magnetism", "Chemistry and Cooking", "Waves", "Natural Disasters", "Liquids", "Pressure", "Color and Light", "Momentum and Inertia", "Illusions", and "The Senses". The two-hour workshops, held one weekend on campus, emphasize hands-on experiments involving both the kids and the parents. Handouts for each workshop give instructions for doing several experiments at home. This program has been a great success for all involved: the college students gain insight into an aspect of science and what it takes to develop and teach that topic, the elementary school students participate in an exciting and challenging scientific exploration, and the parents have a chance to learn some science while spending time working on projects with their children. We provide an overview of the pedagogical aims of our current approach and a sense of the time-line for putting together such a program in a month.

  7. Human LRRK2 G2019S mutation represses post-synaptic protein PSD95 and causes cognitive impairment in transgenic mice.

    Science.gov (United States)

    Adeosun, Samuel O; Hou, Xu; Zheng, Baoying; Melrose, Heather L; Mosley, Thomas; Wang, Jun Ming

    2017-07-01

    LRRK2 G2019S mutation is associated with increased kinase activity and is the most common mutation associated with late-onset PD. However, the transgenic mouse model has not recapitulated cardinal PD-related motor phenotypes. Non-motor symptoms of PD including cognitive impairments are very common and may appear earlier than the motor symptoms. The objective of this study was to determine whether human LRRK2 with G2019S mutation causes hippocampus-dependent cognitive deficits in mice. Male (LRRK2-G2019S) LRRK2-Tg mice showed impairments in the early portion of the Two-day radial arm water maze acquisition trial as well as in the reversal learning on the third day. However, their performance was similar to Non-Tg controls in the probe trial. LRRK2-Tg mice also displayed impairments in the novel arm discrimination test but not in the spontaneous alternation test in Y-maze. Interestingly, there was no statistically significant locomotor impairment during any of these cognitive test, nor in the locomotor tests including open field, accelerating rotarod and pole tests. Expression of the postsynaptic protein PSD-95 but not the presynaptic protein synaptophysin was lower in hippocampal homogenates of LRRK2-Tg mice. Consistent with previous reports in human LRRK2 G2019S carriers, the current data suggests that cognitive dysfunctions are present in LRRK2-Tg mice even in the absence of locomotor impairment. LRRK2 G2019S mutation represses the postsynaptic protein PSD-95 but not the presynaptic protein synaptophysin. This study also suggests that mild cognitive impairment may appear earlier than motor dysfunctions in LRRK2-G2019S mutation carriers. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Science and data science.

    Science.gov (United States)

    Blei, David M; Smyth, Padhraic

    2017-08-07

    Data science has attracted a lot of attention, promising to turn vast amounts of data into useful predictions and insights. In this article, we ask why scientists should care about data science. To answer, we discuss data science from three perspectives: statistical, computational, and human. Although each of the three is a critical component of data science, we argue that the effective combination of all three components is the essence of what data science is about.

  9. Here, There, and Everywhere: A Case Study of Science through Analogy, Near and Far

    Science.gov (United States)

    Watzke, M.; Arcand, K.

    2014-07-01

    Here, There, and Everywhere (HTE) is a program that consists of a series of exhibitions, posters, and supporting hands-on activities that utilize analogies in the teaching of science, engineering, and technology to provide multi-generational and family-friendly content in English and Spanish to small community centers, libraries, and under-resourced small science centers. The purpose of the program is to connect crosscutting science content (in earth, atmospheric and planetary sciences, and astrophysics) with everyday phenomena. By using different modes of content delivery (physical exhibits and handouts, interpretive stations, facilitated activities for educators, and online resources), HTE helps to demonstrate the universality of physical laws and the connection between our everyday world and the universe as a whole to members of the public who may not identify strongly with science. HTE is part of a series of so-called public science projects created and developed by the Education and Public Outreach (EPO) group at the Chandra X-ray Center (CXC). This paper will outline how HTE fits into the lineage of this particular type of science outreach that aims to engage the greater public in non-traditional venues for science learning and appreciation.

  10. Science in Science Fiction.

    Science.gov (United States)

    Allday, Jonathan

    2003-01-01

    Offers some suggestions as to how science fiction, especially television science fiction programs such as "Star Trek" and "Star Wars", can be drawn into physics lessons to illuminate some interesting issues. (Author/KHR)

  11. Advancing Pre-college Science and Mathematics Education

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Rick [General Atomics, San Diego, CA (United States)

    2015-05-06

    With support from the US Department of Energy, Office of Science, Fusion Energy Sciences, and General Atomics, an educational and outreach program primarily for grades G6-G13 was developed using the basic science of plasma and fusion as the content foundation. The program period was 1994 - 2015 and provided many students and teachers unique experiences such as a visit to the DIII-D National Fusion Facility to tour the nation’s premiere tokamak facility or to interact with interesting and informative demonstration equipment and have the opportunity to increase their understanding of a wide range of scientific content, including states of matter, the electromagnetic spectrum, radiation & radioactivity, and much more. Engaging activities were developed for classroom-size audiences, many made by teachers in Build-it Day workshops. Scientist and engineer team members visited classrooms, participated in science expositions, held workshops, produced informational handouts in paper, video, online, and gaming-CD format. Participants could interact with team members from different institutions and countries and gain a wider view of the world of science and engineering educational and career possibilities. In addition, multiple science stage shows were presented to audiences of up to 700 persons in a formal theatre setting over a several day period at Science & Technology Education Partnership (STEP) Conferences. Annually repeated participation by team members in various classroom and public venue events allowed for the development of excellent interactive skills when working with students, teachers, and educational administrative staff members. We believe this program has had a positive impact in science understanding and the role of the Department of Energy in fusion research on thousands of students, teachers, and members of the general public through various interactive venues.

  12. A New Approach to Teaching Science to Elementary Education Majors in Response to the NGSS

    Science.gov (United States)

    Brevik, C.; Daniels, L.; McCoy, C.

    2015-12-01

    The Next Generation Science Standards (NGSS) place an equal emphasis on science process skills and science content. The goal is to have K-12 students "doing" science, not just "learning about" science. However, most traditional college science classes for elementary education majors place a much stronger emphasis on science content knowledge with the hands-on portion limited to a once-a-week lab. The two models of instruction are not aligned. The result is that many elementary school teachers are unprepared to offer interactive science with their students. Without additional coaching, many teachers fall back on the format they learned in college - lecture, handouts, homework. If we want teachers to use more hands-on methods in the classroom, these techniques should be taught to elementary education majors when they are in college. Dickinson State University has begun a collaboration between the Teacher Education Department and the Department of Natural Sciences. The physical science course for elementary education majors has been completely redesigned to focus equally on the needed science content and the science process skills emphasized by the NGSS. The format of the course has been adjusted to more closely mirror a traditional K-5 classroom; the course meets for 50 minutes five days a week. A flipped-classroom model has been adopted to ensure no content is lost, and hands-on activities are done almost every day as new concepts are discussed. In order to judge the effectiveness of these changes, a survey tool was administered to determine if there was a shift in the students' perception of science as an active instead of a passive field of study. The survey also measured the students' comfort-level in offering a hands-on learning environment in their future classrooms and their confidence in their ability to effectively teach science concepts to elementary students. Results from the first year of the study will be presented.

  13. Pre-Service Teachers Methods of Teaching Science

    Directory of Open Access Journals (Sweden)

    Dr. Raquel C. Pambid

    2015-02-01

    Full Text Available The study described the teaching methods used by pre-service teachers in Science. It focused on the strategies, techniques, materials, innovative methods and pattern of teaching science used by the pre-service teachers as described in their lesson plans. The qualitative and quantitative design was used in the study. The books, teacher hand-outs from classroom lectures were the sources of methods, strategies and techniques. The chalkboard and self-made drawings and charts were the materials often used. Conventional methods like lecture, open class discussion and demonstration were commonly employed. The strategies included group discussion, use of motivating questions and stories to arouse the interest of students. The direct eye contact, body expressions, jokes and news/trivia were frequent techniques. Integration of values in the lesson became less as the year level increases. The pattern of teaching drawn followed the formal style: I Objectives, II Subject matter, III Learning Tasks, IV Synthesis of the lesson, V Assessment and VI Enrichment. The conventional method and pattern of teaching by the pre-service teachers of PSU suggest that students in the College of Teacher Education should be trained to be more innovative and open in trying out more advanced teaching methods. Furthermore, PSU science pre-service teachers should use methods which can develop higher order thinking skills among high school students.

  14. Science in Computational Sciences

    Directory of Open Access Journals (Sweden)

    Jameson Cerrosen

    2012-12-01

    Full Text Available The existing theory in relation to science presents the physics as an ideal, although many sciences not approach the same, so that the current philosophy of science-Theory of Science- is not much help when it comes to analyze the computer science, an emerging field of knowledge that aims investigation of computers, which are included in the materialization of the ideas that try to structure the knowledge and information about the world. Computer Science is based on logic and mathematics, but both theoretical research methods and experimental follow patterns of classical scientific fields. Modeling and computer simulation, as a method, are specific to the discipline and will be further developed in the near future, not only applied to computers but also to other scientific fields. In this article it is analyze the aspects of science in computer science, is presenting an approach to the definition of science and the scientific method in general and describes the relationships between science, research, development and technology.

  15. NASA's Planetary Science Missions and Participations

    Science.gov (United States)

    Daou, Doris; Green, James L.

    2017-04-01

    NASA's Planetary Science Division (PSD) and space agencies around the world are collaborating on an extensive array of missions exploring our solar system. Planetary science missions are conducted by some of the most sophisticated robots ever built. International collaboration is an essential part of what we do. NASA has always encouraged international participation on our missions both strategic (ie: Mars 2020) and competitive (ie: Discovery and New Frontiers) and other Space Agencies have reciprocated and invited NASA investigators to participate in their missions. NASA PSD has partnerships with virtually every major space agency. For example, NASA has had a long and very fruitful collaboration with ESA. ESA has been involved in the Cassini mission and, currently, NASA funded scientists are involved in the Rosetta mission (3 full instruments, part of another), BepiColombo mission (1 instrument in the Italian Space Agency's instrument suite), and the Jupiter Icy Moon Explorer mission (1 instrument and parts of two others). In concert with ESA's Mars missions NASA has an instrument on the Mars Express mission, the orbit-ground communications package on the Trace Gas Orbiter (launched in March 2016) and part of the DLR/Mars Organic Molecule Analyzer instruments going onboard the ExoMars Rover (to be launched in 2018). NASA's Planetary Science Division has continuously provided its U.S. planetary science community with opportunities to include international participation on NASA missions too. For example, NASA's Discovery and New Frontiers Programs provide U.S. scientists the opportunity to assemble international teams and design exciting, focused planetary science investigations that would deepen the knowledge of our Solar System. The PSD put out an international call for instruments on the Mars 2020 mission. This procurement led to the selection of Spain and Norway scientist leading two instruments and French scientists providing a significant portion of another

  16. Science, Philosophy of Science and Science Teaching.

    Science.gov (United States)

    Elkana, Yehuda

    2000-01-01

    Discusses the evolution of science through historical accounts. History should become an integral part of science teaching at all levels as it is through history of science that students can become aware of the open nature of science, and more importantly, of the open nature of methods by which science can be done. (Author/SAH)

  17. Science or Science Fiction?

    DEFF Research Database (Denmark)

    Lefsrud, Lianne M.; Meyer, Renate

    2012-01-01

    This paper examines the framings and identity work associated with professionals’ discursive construction of climate change science, their legitimation of themselves as experts on ‘the truth’, and their attitudes towards regulatory measures. Drawing from survey responses of 1077 professional......, legitimation strategies, and use of emotionality and metaphor. By linking notions of the science or science fiction of climate change to the assessment of the adequacy of global and local policies and of potential organizational responses, we contribute to the understanding of ‘defensive institutional work...

  18. Bush blasts 'filth' on TV, school condom handouts.

    Science.gov (United States)

    1991-12-18

    President Bush complained yesterday about the "filth and indecent material" that Americans are exposed to through televised trials. Mr. Bush also criticized programs to combat AIDS that give condoms to teenagers and clean needles to drug addicts. He said such efforts undermine traditional values. He expressed hope that Earvin "Magic" Johnson's revelation that he is HIV positive "will teach people that wayward lifestyles or just kind of unsafe sex at random is not the way it ought to work." Mr. Bush made the comments in a series of satellite television interviews with ABC affiliates in major cities. In an apparent reaction to graphic testimony at the recent Palm Beach rape trial of William Kennedy Smith, Mr. Bush said, "I think the American people have a right to be protected against some of these excesses." Mr. Smith, a nephew of Sen. Edward M. Kennedy, D-Mass., was acquitted last week. The Cable News Network and Court TV provided virtually gavel-to-gavel coverage. Mr. Bush took a dim view of a plan to distribute condoms to juniors and seniors in Philadelphia city high schools as part of a program to combat acquired immune deficiency syndrome. "This is a disease that can be controlled for the most part by individual behavior," Mr. Bush said. "Indeed, I must tell you I'm worried about it. I'm worried about so much filth and indecent material coming in through the airwaves and through these trials into people's homes," he said. full text

  19. Understanding the Theory of Multiple Intelligences. Staff Workshop Handout

    Science.gov (United States)

    Early Childhood Today, 2005

    2005-01-01

    In his "Theory of Multiple Intelligences," Dr. Howard Gardner expands the concept of intelligence to include such areas as music, spatial relations, and interpersonal knowledge in addition to the traditional view of two intelligences--mathematical and linguistic. Using biological as well as cultural research, Gardner formulated a list of seven…

  20. Indiana Air Pollution Control Board Approves a Modification on a PSD Permit for General Motors in which Two Coal-Fired Boilers are Forgiven a SO2 Control Requirement

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  1. Análise comparativa do conteúdo Filo Mollusca em livro didático e apostilas do ensino médio de Cascavel, Paraná Comparative analysis of the Phylum Mollusca contents in a high school instructional book and in teacher's notes/handouts at Cascavel, Paraná, Brazil

    Directory of Open Access Journals (Sweden)

    Juliana Cristina dos Santos

    2007-12-01

    Full Text Available O objetivo deste trabalho foi realizar uma análise comparativa entre um livro didático de Biologia utilizado na terceira série do Ensino Médio, da rede estadual de ensino do município de Cascavel, PR, e apostilas utilizadas por duas escolas da rede privada. Após o levantamento e escolha, os materiais didáticos foram submetidos a uma análise geral em relação à capa, encadernação, espaçamento entre linhas, tamanho da letra, ilustrações, quadros e tabelas, e, também, a uma análise específica do conteúdo Filo Mollusca, considerando-se conceitos; sugestões de leituras complementares; erros ortográficos e conceituais; erros de impressão e revisão; ilustrações. Verificou-se que todos os materiais didáticos analisados apresentam falhas. No entanto, em umas das apostilas, foram encontradas mais falhas, pois além do seu conteúdo ser extremamente sucinto e não apresentar um planejamento em relação às atividades propostas, continha imagens incorretas e sem legendas auto-explicativas.The objective of this work was to carry out a comparative analysis between an instructional Biology book used in the junior year of high school in the school network system of the State of Paraná at the municipality of Cascavel, PR, and teacher's notes/handouts used by two schools in the private school network. After surveying and selecting the materials, these were submitted to a general analysis with regard to their cover, binding, line spacing, font size, illustrations, charts and tables, and also to a specific analysis in relation to their Phylum Mollusca contents, in which concepts, supplementary reading suggestions, typos and conceptual errors, printing and proofreading errors, and illustrations were taken into consideration. It was observed that all learning materials analyzed showed imperfections; however, a higher number of imperfections was found in one set of teacher's notes, because besides having an extremely succinct content and

  2. Primary Science Interview: Science Sparks

    Science.gov (United States)

    Bianchi, Lynne

    2016-01-01

    In this "Primary Science" interview, Lynne Bianchi talks with Emma Vanstone about "Science Sparks," which is a website full of creative, fun, and exciting science activity ideas for children of primary-school age. "Science Sparks" started with the aim of inspiring more parents to do science at home with their…

  3. Communicating Science

    Science.gov (United States)

    Russell, Nicholas

    2009-10-01

    Introduction: what this book is about and why you might want to read it; Prologue: three orphans share a common paternity: professional science communication, popular journalism, and literary fiction are not as separate as they seem; Part I. Professional Science Communication: 1. Spreading the word: the endless struggle to publish professional science; 2. Walk like an Egyptian: the alien feeling of professional science writing; 3. The future's bright? Professional science communication in the age of the internet; 4. Counting the horse's teeth: professional standards in science's barter economy; 5. Separating the wheat from the chaff: peer review on trial; Part II. Science for the Public: What Science Do People Need and How Might They Get It?: 6. The Public Understanding of Science (PUS) movement and its problems; 7. Public engagement with science and technology (PEST): fine principle, difficult practice; 8. Citizen scientists? Democratic input into science policy; 9. Teaching and learning science in schools: implications for popular science communication; Part III. Popular Science Communication: The Press and Broadcasting: 10. What every scientist should know about mass media; 11. What every scientist should know about journalists; 12. The influence of new media; 13. How the media represents science; 14. How should science journalists behave?; Part IV. The Origins of Science in Cultural Context: Five Historic Dramas: 15. A terrible storm in Wittenberg: natural knowledge through sorcery and evil; 16. A terrible storm in the Mediterranean: controlling nature with white magic and religion; 17. Thieving magpies: the subtle art of false projecting; 18. Foolish virtuosi: natural philosophy emerges as a distinct discipline but many cannot take it seriously; 19. Is scientific knowledge 'true' or should it just be 'truthfully' deployed?; Part V. Science in Literature: 20. Science and the Gothic: the three big nineteenth-century monster stories; 21. Science fiction: serious

  4. Science/s.

    Directory of Open Access Journals (Sweden)

    Emmanuelle Tricoire

    2005-03-01

    Full Text Available Un forum a été organisé en mars par la Commission européenne. Il s’appelait « Science in Society ». Depuis 2000 la Commission a mis en place un Plan d’Action élaboré pour que soit promue « la science » au sein du public, afin que les citoyens prennent de bonnes décisions, des décisions informées. Il s’agit donc de développer la réflexivité au sein de la société, pour que cette dernière agisse avec discernement dans un monde qu’elle travaille à rendre durable. ...

  5. Science teachers' understanding and use of instructional strategies within the 4 x 4 block schedule

    Science.gov (United States)

    Grosshans, Kurt

    The primary purpose of this researcher was to investigate how science teachers engage students under the 4 x 4 block schedule and how the teachers' understanding of how they use instructional strategies influenced their lessons. As an inquiry-based approach has been adopted by the National Science Standards, research has suggested that block scheduling provides more time for teachers to incorporate varied strategies such as inquiry-based and cooperative learning teaching which have philosophical roots in a social constructivist philosophy. This research investigated the questions: What instructional strategies do science teachers use to engage students on the 4 x 4 block schedule? How do science teachers understand their use of instructional strategies? The methodology was qualitative in nature and involved a multiple case study of three high school science teachers at a large rural county high school. Data sources included pre-observation interviews, classroom observations, post-observation interviews, and the collection of documents and artifacts such as lesson plans, student hand-outs, worksheets, laboratory exercises, homework and other document(s) the teacher used to prepare for or implement a lesson. The evidence observed in this study, suggests that the strategies used by these three science teachers remain mostly didactic in nature. Although the teachers reported in the interview phase of this research that they use a wide variety of strategies, what was observed within the 4 x 4 block structure was the use of different didactic strategies, not different holistic strategies. Although the teachers were aware of more holistic strategies such as inquiry-based and cooperative learning, they were not adopted nor adapted within the lesson. The three teachers used strategies that were consistent with their scientific realist views concerning the nature of science. These scientific realist philosophies are antithetical to a social constructivist approach to

  6. Science Fiction and Science Education.

    Science.gov (United States)

    Cavanaugh, Terence

    2002-01-01

    Uses science fiction films such as "Jurassic Park" or "Anaconda" to teach science concepts while fostering student interest. Advocates science fiction as a teaching tool to improve learning and motivation. Describes how to use science fiction in the classroom with the sample activity Twister. (YDS)

  7. Pure Science and Applied Science*

    OpenAIRE

    Aumann, Robert J

    2011-01-01

    (Excerpt) The name of my talk is Pure Science and Applied Science, and the idea I would like to sell to you today is that there is no such thing as “pure” or “applied” science. In other words, there is such a thing as science, but there is no difference between pure and applied science. Science is one entity and cannot be separated into different categories. In order to back that up, I would like to tell you a little story. As an undergraduate, I studied mathematics at City College in New...

  8. Sound Science

    Science.gov (United States)

    Sickel, Aaron J.; Lee, Michele H.; Pareja, Enrique M.

    2010-01-01

    How can a teacher simultaneously teach science concepts through inquiry while helping students learn about the nature of science? After pondering this question in their own teaching, the authors developed a 5E learning cycle lesson (Bybee et al. 2006) that concurrently embeds opportunities for fourth-grade students to (a) learn a science concept,…

  9. Science and Science Fiction Films.

    Science.gov (United States)

    Dubeck, Leroy W.

    1981-01-01

    Describes an undergraduate physics course for nonscience majors which combines physics with science fiction films. Includes course format, sample module on the concept of momentum, and an appendix with a listing of science fiction films used in this course. (DS)

  10. Psycho-Motor and Error Enabled Simulations: Modeling Vulnerable Skills in the Pre-Mastery Phase Medical Practice Initiative Procedural Skill Decay and Maintenance (MPI-PSD)

    Science.gov (United States)

    2014-04-01

    One station focuses on the abilities to detect applied forces and match those forces with precision. This station also involves scenarios where...seeking a Master’s of Science in Kinesiology (Motor Behavior and Control emphasis) from University of Wisconsin-Madison. Specializing in hardware...Discriminate between different degrees of stiffness Maintain desired position of the virtual stylus (cursor) Detect the direction of applied

  11. Open Science

    Directory of Open Access Journals (Sweden)

    Süreyya Çankırı

    2017-10-01

    Full Text Available Science is based on the confirmation of phenomena and events in a continuum. In the development of science; the cumulative progress and effective sharing of information comes to the forefront. Within the scope of science, producing new information requires a social approach. Because science has more participants every day so the meaning and importance of science also becomes different. In this sense, the idea of open science, which is based on open access, open data and open source, continues to mediate the socialization of information as well as the purpose of the rapid spread of scientific research results among scientists. In the editorial section, the approach of open science, which has gained momentum in recent years, is evaluated in the context of information retrieval and interaction.

  12. Cognitive science

    OpenAIRE

    John N. Drobak

    2010-01-01

    Cognitive science is the study of intelligence and intelligent systems. Several disciplines including psychology, philosophy, linguistics and the neurosciences have well-established interests in these topics. Cognitive science is an attempt to organise and unify views of thought developed within these distinct disciplines. Cognitive Science is concerned with the construction of abstract theory of intelligent processes, the investigation of human and animal intelligence with the goal of develo...

  13. Science Bubbles

    DEFF Research Database (Denmark)

    Hendricks, Vincent Fella; Pedersen, David Budtz

    2013-01-01

    Much like the trade and trait sof bubbles in financial markets,similar bubbles appear on the science market. When economic bubbles burst, the drop in prices causes the crash of unsustainable investments leading to an investor confidence crisis possibly followed by a financial panic. But when...... bubbles appear in science, truth and reliability are the first victims. This paper explores how fashions in research funding and research management may turn science into something like a bubble economy....

  14. Science Notes.

    Science.gov (United States)

    School Science Review, 1987

    1987-01-01

    Contains 31 activities and experiments from the biological and physical sciences. Addresses such areas as reproduction, biotechnology, ecology, proteins, nitrates, aerosols, metal crystallinity, circuit boards, and photoswitching. (ML)

  15. Science Shops

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard

    1999-01-01

    The paper prsents the overall concept of science shops as practised in most of the European science shops and present the concept practised and some experience obtained at the Technical University of Denmark. An outline for the planning of new sceince shops is presented.......The paper prsents the overall concept of science shops as practised in most of the European science shops and present the concept practised and some experience obtained at the Technical University of Denmark. An outline for the planning of new sceince shops is presented....

  16. Science Fairs for Science Literacy

    Science.gov (United States)

    Mackey, K. R.

    2014-12-01

    Science literacy is imperative for well informed civic and personal decision making, yet only a quarter of American adults are proficient enough in science to understand science stories reported in the popular press. Hands-on research increases confidence in and understanding of science. When guiding students in designing and conducting science fair projects, mentors can foster science literacy by helping students focus on three goals: (1) articulating hypotheses or questions, (2) designing feasible projects, and (3) learning to make and interpret graphs. These objectives introduce students to the methodological nature of scientific research and give them the tools to interpret scientific facts and data in order to make informed decisions for themselves and society.

  17. The science in social science

    OpenAIRE

    Bernard, H. Russell

    2012-01-01

    A recent poll showed that most people think of science as technology and engineering—life-saving drugs, computers, space exploration, and so on. This was, in fact, the promise of the founders of modern science in the 17th century. It is less commonly understood that social and behavioral sciences have also produced technologies and engineering that dominate our everyday lives. These include polling, marketing, management, insurance, and public health programs.

  18. Marine Science

    African Journals Online (AJOL)

    sustainable coastal development in the region, as well as contributing to the global base of marine science. The journal publishes original research articles dealing with all aspects of marine science and coastal manage- ment. Topics include, but are not limited to: theoretical studies, oceanography, marine biology and ...

  19. Marine Science

    African Journals Online (AJOL)

    The journal publishes original research articles dealing with all aspects of marine science and coastal manage- ment. ... Science (WIOJMS), as a special issue entitled “Coral reefs of Mauritius in a changing global climate”. ...... 2014) with the highest disaster risk exposed to natural hazards, including storms and floods.

  20. Life sciences

    Energy Technology Data Exchange (ETDEWEB)

    Day, L. (ed.)

    1991-04-01

    This document is the 1989--1990 Annual Report for the Life Sciences Divisions of the University of California/Lawrence Berkeley Laboratory. Specific progress reports are included for the Cell and Molecular Biology Division, the Research Medicine and Radiation Biophysics Division (including the Advanced Light Source Life Sciences Center), and the Chemical Biodynamics Division. 450 refs., 46 figs. (MHB)

  1. Marine Science

    African Journals Online (AJOL)

    sustainable use of coastal and marine resources. This is central to the goal of supporting and promoting sustainable coastal development in the region, as well as contributing to the global base of marine science. The journal publishes original research articles dealing with all aspects of marine science and coastal manage-.

  2. Science Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 2. Science Matters A Book for Curious Minds. Rohini Godbole. Book Review Volume 2 Issue 2 February 1997 pp 94-95. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/002/02/0094-0095 ...

  3. Marine Science

    African Journals Online (AJOL)

    Chief Editor José Paula | Faculty of Sciences of University of Lisbon, Portugal. Copy Editor ... sustainable coastal development in the region, as well as contributing to the global base of marine science. ... salt works along the coast of Ungwana Bay provide alternative fishing grounds for local fishers unable to venture.

  4. Marine Science

    African Journals Online (AJOL)

    Aims and scope: The Western Indian Ocean Journal of Marine Science provides an avenue for the wide dissem- ination of high ... The journal publishes original research articles dealing with all aspects of marine science and coastal manage- ment. Topics ..... of enteric pathogens from warm-blooded animals, including ...

  5. The sciences of science communication.

    Science.gov (United States)

    Fischhoff, Baruch

    2013-08-20

    The May 2012 Sackler Colloquium on "The Science of Science Communication" brought together scientists with research to communicate and scientists whose research could facilitate that communication. The latter include decision scientists who can identify the scientific results that an audience needs to know, from among all of the scientific results that it would be nice to know; behavioral scientists who can design ways to convey those results and then evaluate the success of those attempts; and social scientists who can create the channels needed for trustworthy communications. This overview offers an introduction to these communication sciences and their roles in science-based communication programs.

  6. Proteome analysis of vaccinia virus IHD-W-infected HEK 293 cells with 2-dimensional gel electrophoresis and MALDI-PSD-TOF MS of on solid phase support N-terminally sulfonated peptides

    Directory of Open Access Journals (Sweden)

    Bartel Sebastian

    2011-08-01

    Full Text Available Abstract Background Despite the successful eradication of smallpox by the WHO-led vaccination programme, pox virus infections remain a considerable health threat. The possible use of smallpox as a bioterrorism agent as well as the continuous occurrence of zoonotic pox virus infections document the relevance to deepen the understanding for virus host interactions. Since the permissiveness of pox infections is independent of hosts surface receptors, but correlates with the ability of the virus to infiltrate the antiviral host response, it directly depends on the hosts proteome set. In this report the proteome of HEK293 cells infected with Vaccinia Virus strain IHD-W was analyzed by 2-dimensional gel electrophoresis and MALDI-PSD-TOF MS in a bottom-up approach. Results The cellular and viral proteomes of VACV IHD-W infected HEK293 cells, UV-inactivated VACV IHD-W-treated as well as non-infected cells were compared. Derivatization of peptides with 4-sulfophenyl isothiocyanate (SPITC carried out on ZipTipμ-C18 columns enabled protein identification via the peptides' primary sequence, providing improved s/n ratios as well as signal intensities of the PSD spectra. The expression of more than 24 human proteins was modulated by the viral infection. Effects of UV-inactivated and infectious viruses on the hosts' proteome concerning energy metabolism and proteins associated with gene expression and protein-biosynthesis were quite similar. These effects might therefore be attributed to virus entry and virion proteins. However, the modulation of proteins involved in apoptosis was clearly correlated to infectious viruses. Conclusions The proteome analysis of infected cells provides insight into apoptosis modulation, regulation of cellular gene expression and the regulation of energy metabolism. The confidence of protein identifications was clearly improved by the peptides' derivatization with SPITC on a solid phase support. Some of the identified proteins

  7. Science teaching in science education

    Science.gov (United States)

    Callahan, Brendan E.; Dopico, Eduardo

    2016-06-01

    Reading the interesting article Discerning selective traditions in science education by Per Sund , which is published in this issue of CSSE, allows us to open the discussion on procedures for teaching science today. Clearly there is overlap between the teaching of science and other areas of knowledge. However, we must constantly develop new methods to teach and differentiate between science education and teaching science in response to the changing needs of our students, and we must analyze what role teachers and teacher educators play in both. We must continually examine the methods and concepts involved in developing pedagogical content knowledge in science teachers. Otherwise, the possibility that these routines, based on subjective traditions, prevent emerging processes of educational innovation. Modern science is an enormous field of knowledge in its own right, which is made more expansive when examined within the context of its place in society. We propose the need to design educative interactions around situations that involve science and society. Science education must provide students with all four dimensions of the cognitive process: factual knowledge, conceptual knowledge, procedural knowledge, and metacognitive knowledge. We can observe in classrooms at all levels of education that students understand the concepts better when they have the opportunity to apply the scientific knowledge in a personally relevant way. When students find value in practical exercises and they are provided opportunities to reinterpret their experiences, greater learning gains are achieved. In this sense, a key aspect of educational innovation is the change in teaching methodology. We need new tools to respond to new problems. A shift in teacher education is needed to realize the rewards of situating science questions in a societal context and opening classroom doors to active methodologies in science education to promote meaningful learning through meaningful teaching.

  8. Revolutionary Science.

    Science.gov (United States)

    Casadevall, Arturo; Fang, Ferric C

    2016-03-01

    On rare occasions in the history of science, remarkable discoveries transform human society and forever alter mankind's view of the world. Examples of such discoveries include the heliocentric theory, Newtonian physics, the germ theory of disease, quantum theory, plate tectonics and the discovery that DNA carries genetic information. The science philosopher Thomas Kuhn famously described science as long periods of normality punctuated by times of crisis, when anomalous observations culminate in revolutionary changes that replace one paradigm with another. This essay examines several transformative discoveries in the light of Kuhn's formulation. We find that each scientific revolution is unique, with disparate origins that may include puzzle solving, serendipity, inspiration, or a convergence of disparate observations. The causes of revolutionary science are varied and lack an obvious common structure. Moreover, it can be difficult to draw a clear distinction between so-called normal and revolutionary science. Revolutionary discoveries often emerge from basic science and are critically dependent on nonrevolutionary research. Revolutionary discoveries may be conceptual or technological in nature, lead to the creation of new fields, and have a lasting impact on many fields in addition to the field from which they emerge. In contrast to political revolutions, scientific revolutions do not necessarily require the destruction of the previous order. For humanity to continue to benefit from revolutionary discoveries, a broad palette of scientific inquiry with a particular emphasis on basic science should be supported. Copyright © 2016 Casadevall and Fang.

  9. Revolutionary Science

    Directory of Open Access Journals (Sweden)

    Arturo Casadevall

    2016-05-01

    Full Text Available On rare occasions in the history of science, remarkable discoveries transform human society and forever alter mankind’s view of the world. Examples of such discoveries include the heliocentric theory, Newtonian physics, the germ theory of disease, quantum theory, plate tectonics and the discovery that DNA carries genetic information. The science philosopher Thomas Kuhn famously described science as long periods of normality punctuated by times of crisis, when anomalous observations culminate in revolutionary changes that replace one paradigm with another. This essay examines several transformative discoveries in the light of Kuhn’s formulation. We find that each scientific revolution is unique, with disparate origins that may include puzzle solving, serendipity, inspiration, or a convergence of disparate observations. The causes of revolutionary science are varied and lack an obvious common structure. Moreover, it can be difficult to draw a clear distinction between so-called normal and revolutionary science. Revolutionary discoveries often emerge from basic science and are critically dependent on nonrevolutionary research. Revolutionary discoveries may be conceptual or technological in nature, lead to the creation of new fields, and have a lasting impact on many fields in addition to the field from which they emerge. In contrast to political revolutions, scientific revolutions do not necessarily require the destruction of the previous order. For humanity to continue to benefit from revolutionary discoveries, a broad palette of scientific inquiry with a particular emphasis on basic science should be supported.

  10. Saturday Science

    Science.gov (United States)

    Shugart, Cecil G.

    1976-01-01

    Describes the organization of demonstration oriented seminars in which the physics of toys, music, sports and other topics are investigated. Reports that this university based service has increased high school physics and science fair enrollments. (CP)

  11. Forensic Science.

    Science.gov (United States)

    Brettell, T. A.; Saferstein, R.

    1989-01-01

    Presents a review of articles appealing to forensic practitioners. Topics include: drugs and poisons, forensic biochemistry, and trace evidence. Lists noteworthy books published on forensic science topics since 1986. (MVL)

  12. Science Notes.

    Science.gov (United States)

    Thurman, Shirley; And Others

    1988-01-01

    Describes 36 science activities. Topics include: osmosis, fermentation, anhydrobiotic organisms, breathing monitors, trypsin, weeds, amyloplasts, electrolysis, polarimeters, ethene ripening of fruit, colorimetry, diffusion, redox reactions, equilibria, acid-base relationships, electricity, power, resonance, measurement, parallax, amplifiers,…

  13. Scuba Science.

    Science.gov (United States)

    Glickstein, Neil

    2000-01-01

    Introduces an integrated unit on scuba science. Studies oxygen in kinetic theory, Boyle's law, Charles's law, Dalton's law, human circulatory and respiratory systems, and diving dangers such as decompression sickness. (YDS)

  14. Science Topics

    Science.gov (United States)

    EPA is one of the world’s leading environmental and human health research organizations. Science provides the foundation for Agency policies, actions, and decisions made on behalf of the American people.

  15. Marine Science

    African Journals Online (AJOL)

    Aims and scope: The Western Indian Ocean Journal of Marine Science ... Topics include, but are not limited to: theoretical studies, oceanography, marine biology and ... While no populations of seals are resident in the tropical Indian Ocean, ...

  16. Marine Science

    African Journals Online (AJOL)

    Aims and scope: The Western Indian Ocean Journal of Marine Science provides an avenue ... Topics include, but are not limited to: theoretical studies, oceanography, marine biology and ecology, .... population of Chumbe Island Coral Park,.

  17. International Conference-Session of the Section of Nuclear Physics of the Physical Sciences Division of RAS

    CERN Document Server

    2014-01-01

    From November 17 to 21, 2014 the Section of Nuclear Physics of the Physical Sciences Division of the Russian Academy of Sciences and the National Research Nuclear University MEPhI will hold in MEPhI, Moscow, the International Conference-Session of SNP PSD RAS "Physics of Fundamental Interactions". The program of the session covers basic theoretical and experimental aspects of particle physics and related problems of nuclear physics and cosmology, and will consist of 30-minute highlight and review talks as well as 10-15-minute contributed reports. All highlight talks and part of contributed reports will be presented at plenary sessions of the conference. The remaining reports will be presented at the sections which will be formed after receiving of abstracts. On the recommendation of the Organizing Committee reports and talks containing new unpublished results will be published in special issues of journals "Nuclear Physics" and "Nuclear Physics and Engineering". For the institutions belonging to the Rosatom s...

  18. JPRS Report Science & Technology USSR: Life Sciences

    National Research Council Canada - National Science Library

    1988-01-01

    ...: Life sciences, aerospace medicine, agriculture science, biochemistry, biophysics, genetics, immunology, industrial medicine, laser bioeffects, medicine, molecular biology, nonionizing radiation...

  19. Science Fiction Aids Science Teaching.

    Science.gov (United States)

    Dubeck, Leroy W.; And Others

    1990-01-01

    Cited are the experiences of the authors with a college-level course which used science fiction films to teach scientific principles. Included is a set of sample scientific concepts explored using the film "Forbidden Planet." (CW)

  20. Expanding the basic science debate: the role of physics knowledge in interpreting clinical findings.

    Science.gov (United States)

    Goldszmidt, Mark; Minda, John Paul; Devantier, Sarah L; Skye, Aimee L; Woods, Nicole N

    2012-10-01

    Current research suggests a role for biomedical knowledge in learning and retaining concepts related to medical diagnosis. However, learning may be influenced by other, non-biomedical knowledge. We explored this idea using an experimental design and examined the effects of causal knowledge on the learning, retention, and interpretation of medical information. Participants studied a handout about several respiratory disorders and how to interpret respiratory exam findings. The control group received the information in standard "textbook" format and the experimental group was presented with the same information as well as a causal explanation about how sound travels through lungs in both the normal and disease states. Comprehension and memory of the information was evaluated with a multiple-choice exam. Several questions that were not related to the causal knowledge served as control items. Questions related to the interpretation of physical exam findings served as the critical test items. The experimental group outperformed the control group on the critical test items, and our study shows that a causal explanation can improve a student's memory for interpreting clinical details. We suggest an expansion of which basic sciences are considered fundamental to medical education.

  1. Pure Science and Applied Science

    Directory of Open Access Journals (Sweden)

    Robert J. Aumann

    2011-01-01

    Full Text Available (Excerpt The name of my talk is Pure Science and Applied Science, and the idea I would like to sell to you today is that there is no such thing as “pure” or “applied” science. In other words, there is such a thing as science, but there is no difference between pure and applied science. Science is one entity and cannot be separated into different categories. In order to back that up, I would like to tell you a little story. As an undergraduate, I studied mathematics at City College in New York. At that time, what was called Pure Mathematics was in vogue, and the more prominent mathematicians were a little contemptuous of any kind of application. A very famous, prominent mathematician in the first half of the previous century by the name of G. H. Hardy, who was in a branch of mathematics called number theory, said that the only thing he regretted was that he unwittingly did some important work in mathematical genetics that eventually turned out to have some application. … Such was the atmosphere in the late ’40s of the previous century and, being a young man and impressionable, I was swept up in this atmosphere.

  2. Exploring science through science fiction

    CERN Document Server

    Luokkala, Barry B

    2014-01-01

    How does Einstein’s description of space and time compare with Dr. Who? Can James Bond really escape from an armor-plated railroad car by cutting through the floor with a laser concealed in a wristwatch? What would it take to create a fully-intelligent android, such as Star Trek’s Commander Data? How might we discover intelligent civilizations on other planets in the galaxy? Is human teleportation possible? Will our technological society ever reach the point at which it becomes lawful to discriminate on the basis of genetic information, as in the movie GATTACA? Exploring Science Through Science Fiction addresses these and other interesting questions, using science fiction as a springboard for discussing fundamental science concepts and cutting-edge science research. The book is designed as a primary text for a college-level course which should appeal to students in the fine arts and humanities as well as to science and engineering students. It includes references to original research papers, landmark scie...

  3. Is normal science good science?

    Directory of Open Access Journals (Sweden)

    Adrianna Kępińska

    2015-09-01

    Full Text Available “Normal science” is a concept introduced by Thomas Kuhn in The Structure of Scientific Revolutions (1962. In Kuhn’s view, normal science means “puzzle solving”, solving problems within the paradigm—framework most successful in solving current major scientific problems—rather than producing major novelties. This paper examines Kuhnian and Popperian accounts of normal science and their criticisms to assess if normal science is good. The advantage of normal science according to Kuhn was “psychological”: subjective satisfaction from successful “puzzle solving”. Popper argues for an “intellectual” science, one that consistently refutes conjectures (hypotheses and offers new ideas rather than focus on personal advantages. His account is criticized as too impersonal and idealistic. Feyerabend’s perspective seems more balanced; he argues for a community that would introduce new ideas, defend old ones, and enable scientists to develop in line with their subjective preferences. The paper concludes that normal science has no one clear-cut set of criteria encompassing its meaning and enabling clear assessment.

  4. Network science

    CERN Document Server

    Barabasi, Albert-Laszlo

    2016-01-01

    Networks are everywhere, from the Internet, to social networks, and the genetic networks that determine our biological existence. Illustrated throughout in full colour, this pioneering textbook, spanning a wide range of topics from physics to computer science, engineering, economics and the social sciences, introduces network science to an interdisciplinary audience. From the origins of the six degrees of separation to explaining why networks are robust to random failures, the author explores how viruses like Ebola and H1N1 spread, and why it is that our friends have more friends than we do. Using numerous real-world examples, this innovatively designed text includes clear delineation between undergraduate and graduate level material. The mathematical formulas and derivations are included within Advanced Topics sections, enabling use at a range of levels. Extensive online resources, including films and software for network analysis, make this a multifaceted companion for anyone with an interest in network sci...

  5. Science Fiction on Film.

    Science.gov (United States)

    Burmester, David

    1985-01-01

    Reviews science fiction films used in a science fiction class. Discusses feature films, short science fiction films, short story adaptations, original science fiction pieces and factual science films that enrich literature. (EL)

  6. Nonlinear Science

    CERN Document Server

    Yoshida, Zensho

    2010-01-01

    This book gives a general, basic understanding of the mathematical structure "nonlinearity" that lies in the depths of complex systems. Analyzing the heterogeneity that the prefix "non" represents with respect to notions such as the linear space, integrability and scale hierarchy, "nonlinear science" is explained as a challenge of deconstruction of the modern sciences. This book is not a technical guide to teach mathematical tools of nonlinear analysis, nor a zoology of so-called nonlinear phenomena. By critically analyzing the structure of linear theories, and cl

  7. Islam and Science

    Science.gov (United States)

    Salam, Abdus

    The following sections are included: * The Holy Quran and Science * Modem Science, A Greco- Islamic Legacy * The Decline of Sciences in Islam * The Limitations of Science * Faith and Science * The Present Picture of Sciences in the Islamic Countries * Renaissance of Sciences in Islam * Steps Needed for Building up Sciences in the Islamic Countries * Science Education * Science Foundations in Islam * Technology in Our Countries * Concluding Remarks * REFERENCES

  8. Subterranean science

    Science.gov (United States)

    Paling, Sean; Sadler, Stephen

    2015-05-01

    The deep underground laboratories of the world are no longer the scientific realm of astroparticle physics alone. From Mars rovers to muon tomography, and from radioactive dating to astrobiology, Sean Paling and Stephen Sadler describe the renaissance in the science taking place far beneath our feet.

  9. Marine Science

    African Journals Online (AJOL)

    ination of high quality research generated in the Western Indian Ocean (WIO) region, in particular on the sustainable use of coastal ... The journal publishes original research articles dealing with all aspects of marine science and coastal manage- ment. Topics ..... diatom C-biomass is a result of changes in silicate. Figure 4.

  10. Marine Science

    African Journals Online (AJOL)

    Special Issue 1/ 2017 | Jul 2017 | ISSN: 0856-860X. Western Indian Ocean. J O U R N A L O F. Marine Science. Coral reefs of Mauritius in a changing global climate .... of coral diseases, and Stylophora pistillata-like morphotypes occurring around Mauritius Island, respec- tively. .... (2013) assumed that the life cycle of.

  11. Marine Science

    African Journals Online (AJOL)

    sustainable coastal development in the region, as well as contributing to the global base of marine science. .... to accommodate multiple user-groups while con- .... Criteria used to select trawling sites within the survey areas were traw- lability and depth range (100-699 m), and sites were stratified by depth and latitude.

  12. Marine Science

    African Journals Online (AJOL)

    Incomati Estuary and describing forest condition, this study shows the poor condition of peri-urban mangroves at locations such ...... Bay (Kenya) using quickbird satellite imagery. Spa- tial Science 52: 75-86. Neukermans G, Koedam, N (2014) Saco da Inhaca man- grove vegetation mapping and change detection using very ...

  13. Marine Science

    African Journals Online (AJOL)

    Aims and scope: The Western Indian Ocean Journal of Marine Science provides an avenue for the wide dissem- ination of high quality research generated in the Western Indian Ocean (WIO) region, in particular on the sustainable use of coastal and marine resources. This is central to the goal of supporting and promoting.

  14. Brewing Science

    Science.gov (United States)

    Pelter, Michael

    2006-01-01

    Following the brewing process from grain to glass, this course uses the biological and chemical principles of brewing to teach science to the nonscience major. Discussion of the scientific aspects of malting, mashing, fermentation, and the making of different beer styles is complemented by laboratory exercises that use scientific methods to…

  15. Marine Science

    African Journals Online (AJOL)

    Special Issue 1/ 2017 | Jul 2017 | ISSN: 0856-860X. Western ... Sweden. Johan GROENEVELD. South Africa. Issufo HALO. South Africa/Mozambique. Christina HICKS. Australia/UK. Johnson KITHEKA. Kenya. Kassim KULINDWA .... WIO Journal of Marine Science Special Issue 1 / 2017 31-41 | D. Kaullysing et al. sediment ...

  16. Marine Science

    African Journals Online (AJOL)

    Aims and scope: The Western Indian Ocean Journal of Marine Science provides an avenue for the wide dissem- ination of high .... pod diversity and distribution are important especially since studies on marine biodiversity are scarce around Mauritius. .... accurate approach to molluscan systematics. They are helpful in ...

  17. Marine Science

    African Journals Online (AJOL)

    The special issues aim to contribute for advancing marine science in the WIO by focusing on specific themes, geographical areas or assembling contributions from scientific meetings. The editorial processes are exactly the same as for regular issues, with double peer-review, and guest editors are considered. José Paula.

  18. Marine Science

    African Journals Online (AJOL)

    Johan GROENEVELD. South Africa. Issufo HALO. South Africa/Mozambique. Christina HICKS. Australia/UK. Johnson KITHEKA. Kenya. Kassim KULINDWA ... Science (WIOJMS), as a special issue entitled “Coral reefs of Mauritius in a changing global climate”. ..... This is due to important inputs of groundwater at La.

  19. Skeptical Science.

    Science.gov (United States)

    Scott, Alan J.; Barnhart, Carolyn M.; Parejko, Ken S.; Schultz, Forrest S.; Schultz, Steven E.

    2001-01-01

    Discusses the legitimacy of teaching about astrology, extrasensory perception, UFOs, touch therapy, cloning dinosaurs, or any other unusual claims in the classroom. Suggests that bringing unusual claims to the science classroom is an opportunity to motivate students in the principles of scientific thought. (SAH)

  20. Cognitive Science.

    Science.gov (United States)

    Cocking, Rodney R.; Mestre, Jose P.

    The focus of this paper is on cognitive science as a model for understanding the application of human skills toward effective problem-solving. Sections include: (1) "Introduction" (discussing information processing framework, expert-novice distinctions, schema theory, and learning process); (2) "Application: The Expert-Novice…

  1. Science Smiles

    Indian Academy of Sciences (India)

    Resonance – Journal of Science Education. Current Issue : Vol. 22, Issue 12. Current Issue Volume 22 | Issue 12. December 2017. Home · Volumes & Issues · Categories · Special Issues · Search · Editorial Board · Information for Authors · Subscription ...

  2. Marine Science

    African Journals Online (AJOL)

    Aims and scope: The Western Indian Ocean Journal of Marine Science provides an avenue for the wide dissem- ination of high quality research generated in the Western Indian Ocean (WIO) region, in particular on the sustainable use of coastal and .... taken up to a depth of 5cm using a plastic hand core of. 2.6cm diameter.

  3. Boundless Science

    Science.gov (United States)

    Spilhaus, F.

    2009-04-01

    Our science is critical to understanding the future prospects for life. The laboratory for natural sciences encompasses our planet and reaches into the solar system. The forces of nature respect no boundaries. But, we who try to understand these forces are handicapped by national, political, language, religious, and other concocted barriers. These barriers limit both our effectiveness as scientists and our ability to reach those outside our community who need to know what we have uncovered about our environment. An unencumbered worldwide scientific community has been an objective with limited successes for too long. Action began in earnest after the first world war with the formation of the various scientific Unions and ICSU. Fifty years later Keith Runcorn initiated another approach, when he proposed what quickly became EGS and which has grown and evolved with the merger with EUG. To be truly effective we need to communicate and share comfortably with colleagues worldwide. Personal relationships and trust are required. We count on a high level of ethical behavior within our community. We individually must also be constantly vigilant for the encroachment of the manmade barriers that have held back science through time immemorial. Our scientific organizations cannot achieve this alone. They will facilitate, however, the onus is on each of us to reach out and form interlocking informal communities, which will bring our whole planet-wide community together at many overlapping levels. When we achieve this community, our science will more bountiful and better address the needs of human society.

  4. Marine Science

    African Journals Online (AJOL)

    and trophic organization of the fish community in shallow waters of an impacted tropical habitat. Estu- arine Coastal and Shelf Science 58: 89-98. Hajisamae S, Yeesin P, Ibrahim S (2006) Feeding ecology of two sillaginid fishes and trophic interrelations with other co-existing species in the southern part of. South China Sea.

  5. Organizational Science

    Science.gov (United States)

    Beriwal, Madhu; Clegg, Stewart; Collopy, Fred; McDaniel, Reuben, Jr.; Morgan, Gareth; Sutcliffe, Kathleen; Kaufman, Roger; Marker, Anthony; Selwyn, Neil

    2013-01-01

    Scholars representing the field of organizational science, broadly defined as including many fields--organizational behavior and development, management, workplace performance, and so on--were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might…

  6. Current Science

    Indian Academy of Sciences (India)

    error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the teaching of the theory of evolution

  7. Science and anti-science

    CERN Document Server

    Holton, Gerald

    1997-01-01

    What is good science? What goal--if any--is the proper end of scientific activity? Is there a legitimating authority that scientists mayclaim? Howserious athreat are the anti-science movements? These questions have long been debated but, as Gerald Holton points out, every era must offer its own responses. This book examines these questions not in the abstract but shows their historic roots and the answers emerging from the scientific and political controversies of this century. Employing the case-study method and the concept of scientific thematathat he has pioneered, Holton displays the broad scope of his insight into the workings of science: from the influence of Ernst Mach on twentiethcentury physicists, biologists, psychologists, and other thinkers to the rhetorical strategies used in the work of Albert Einstein, Niels Bohr, and others; from the bickering between Thomas Jefferson and the U.S. Congress over the proper form of federal sponsorship of scientific research to philosophical debates since Oswald...

  8. A Series of MATLAB Learning Modules to Enhance Numerical Competency in Applied Marine Sciences

    Science.gov (United States)

    Fischer, A. M.; Lucieer, V.; Burke, C.

    2016-12-01

    Enhanced numerical competency to navigate the massive data landscapes are critical skills students need to effectively explore, analyse and visualize complex patterns in high-dimensional data for addressing the complexity of many of the world's problems. This is especially the case for interdisciplinary, undergraduate applied marine science programs, where students are required to demonstrate competency in methods and ideas across multiple disciplines. In response to this challenge, we have developed a series of repository-based data exploration, analysis and visualization modules in MATLAB for integration across various attending and online classes within the University of Tasmania. The primary focus of these modules is to teach students to collect, aggregate and interpret data from large on-line marine scientific data repositories to, 1) gain technical skills in discovering, accessing, managing and visualising large, numerous data sources, 2) interpret, analyse and design approaches to visualise these data, and 3) to address, through numerical approaches, complex, real-world problems, that the traditional scientific methods cannot address. All modules, implemented through a MATLAB live script, include a short recorded lecture to introduce the topic, a handout that gives an overview of the activities, an instructor's manual with a detailed methodology and discussion points, a student assessment (quiz and level-specific challenge task), and a survey. The marine science themes addressed through these modules include biodiversity, habitat mapping, algal blooms and sea surface temperature change and utilize a series of marine science and oceanographic data portals. Through these modules students, with minimal experience in MATLAB or numerical methods are introduced to array indexing, concatenation, sorting, and reshaping, principal component analysis, spectral analysis and unsupervised classification within the context of oceanographic processes, marine geology and

  9. Collaboration for Actionable Climate Science in Hawaii and the US-Affiliated Pacific Islands

    Science.gov (United States)

    Keener, V. W.; Grecni, Z. N.; Helweg, D. A.

    2016-12-01

    Hawaii and the US-Affiliated Pacific Islands (USAPI) encompass more than 2000 islands spread across millions of square miles of ocean. Islands can be high volcanic or low atolls, and vary widely in terms of geography, climate, ecology, language, culture, economies, government, and vulnerability to climate change impacts. For these reasons, meaningful collaboration across research groups and climate organizations is not only helpful, it is mandatory. No single group can address all the needs of every island, stakeholder, or sector, which has led to close collaboration and leveraging of research in the region to fill different niches. The NOAA-funded Pacific Regional Integrated Sciences & Assessments (RISA) program, DOI Pacific Islands Climate Science Center (PICSC), and the DOI LCC the Pacific Islands Climate Change Cooperative (PICCC) all take a stakeholder oriented approach to climate research, and have successfully collaborated on both specific projects and larger initiatives. Examples of these collaborations include comprising the core team of the Pacific Islands Regional Climate Assessment (PIRCA), the regional arm of the US National Climate Assessment, co-sponsoring a workshop on regional downscaling for scientists and managers, leveraging research projects across multiple sectors on a single island, collaborating on communication products such as handouts and websites to ensure a consistent message, and in the case of the Pacific RISA and the PICSC, jointly funding a PIRCA Sustained Assessment Specialist position. Barriers to collaboration have been around topics such as roles of research versus granting groups, perceived research overlap, and funding uncertainties. However, collaborations have been overwhelming positive in the Pacific Islands region due to communication, recognition of partners' strengths and expertise, and especially because of the "umbrella" organization and purpose provided by the PIRCA structure, which provides a shared platform for all

  10. Planetary Science Education - Workshop Concepts for Classrooms and Internships

    Science.gov (United States)

    Musiol, S.; Rosenberg, H.; Rohwer, G.; Balthasar, H.; van Gasselt, S.

    2014-12-01

    the Martian surface and presented their results in the end. Extensive handouts and high-quality print material supplemented face-to-face exercises. For the future we plan to expand our workshop concepts, to give students the possibility of conducting a week-long internship with our Planetary Sciences research group.

  11. Caring Science or Science of Caring.

    Science.gov (United States)

    Turkel, Marian C; Watson, Jean; Giovannoni, Joseph

    2018-01-01

    The concepts caring science and science of caring have different meanings; however, they are often used interchangeably. The purpose of this paper is to present an overview of the synthesis of the scholarly literature on the definitions of the science of caring and caring science and to affirm the authors' perspective relating to the language of caring science. Caring science advances the epistemology and ontology of caring. Ideas related to caring science inquiry are presented, and the authors acknowledge the future of caring science as unitary caring science.

  12. Portraying Real Science in Science Communication

    Science.gov (United States)

    van Dijk, Esther M.

    2011-01-01

    In both formal and informal settings, not only science but also views on the nature of science are communicated. Although there probably is no singular nature shared by all fields of science, in the field of science education it is commonly assumed that on a certain level of generality there is a consensus on many features of science. In this…

  13. Science News and the Science Classroom

    Science.gov (United States)

    McCullough, Laura

    2006-01-01

    Using "Science News" as a teaching tool promotes writing about science, talking about science, and broadening students' views about what science is. This article describes an ongoing assignment in which students choose one article from "Science News" each week and write a brief summary and explanation of why they picked that article. (Contains 1…

  14. The Science in Science Fiction.

    Science.gov (United States)

    Nicholls, Peter, Ed.

    This 12-chapter book discusses the scientific facts behind the ideas included in the novels of Robert Heinlein, Isaac Asimov, Frederik Pohl, Arthur C. Clark and other science fiction writers. Areas explored in the first 11 chapters include: exploration of deep space; energy and exotic power sources; likelihood of extra-terrestrial life and the…

  15. The Science of Filming Science

    Science.gov (United States)

    Harned, D.

    2016-12-01

    Filmmaking is a science. It is observation, data collection, analysis, experimentation, structure, and presentation. Filmmaking is a process that is familiar to scientists. Observation - what we know is gained from observation of the world around us. Film allows us to focus this observation, to pick out details, to understand nuance, to direct seeing. Filmmaking is a tool for learning about the world. Data collection - to study what we observe we must see what it is now, and how it is changing. This element of filmmaking is collecting images, video, documenting events, and gathering information. Analysis - to understand the film data we have collected we must understand connections, correlations, and cause and effect. We ask questions. We discover. Experimentation - film allows us to experiment with different scenarios, to test observations and make models. Structure - what we find or what we want to present must be sorted into a structured format using the tools of writing, filming, and editing. Presentation - the final film is the result of what we observe, what observations we collect, what we learn from those observations, how we test what we've learned, and how we organize and show what we find. Online video is transforming the way we see the world. We now have easy access to lectures by the famous and the obscure; we can observe lab experiments, documentaries of field expeditions, and actually see recent research results. Video is omnipresent in our culture and supplements or even replaces writing in many applications. We can easily present our own scientific results to new and important audiences. Video can do a lot for science and scientists: It can provide an expanded audience for scientific news and information, educate thousands, spread the word about scientific developments, help frame controversial science issues, show real scientists at work in the real world, promote interest in scientific publications, and report on science-agency programs. It can

  16. Computer sciences

    Science.gov (United States)

    Smith, Paul H.

    1988-01-01

    The Computer Science Program provides advanced concepts, techniques, system architectures, algorithms, and software for both space and aeronautics information sciences and computer systems. The overall goal is to provide the technical foundation within NASA for the advancement of computing technology in aerospace applications. The research program is improving the state of knowledge of fundamental aerospace computing principles and advancing computing technology in space applications such as software engineering and information extraction from data collected by scientific instruments in space. The program includes the development of special algorithms and techniques to exploit the computing power provided by high performance parallel processors and special purpose architectures. Research is being conducted in the fundamentals of data base logic and improvement techniques for producing reliable computing systems.

  17. Mechanical science

    CERN Document Server

    Bolton, W C

    2013-01-01

    This book gives comprehensive coverage of mechanical science for HNC/HND students taking mechanical engineering courses, including all topics likely to be covered in both years of such courses, as well as for first year undergraduate courses in mechanical engineering. It features 500 problems with answers and 200 worked examples. The third edition includes a new section on power transmission and an appendix on mathematics to help students with the basic notation of calculus and solution of differential equations.

  18. Specialized science.

    Science.gov (United States)

    Casadevall, Arturo; Fang, Ferric C

    2014-04-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism.

  19. Materials Science

    Science.gov (United States)

    2003-01-01

    The Materials Science Program is structured so that NASA s headquarters is responsible for the program content and selection, through the Enterprise Scientist, and MSFC provides for implementation of ground and flight programs with a Discipline Scientist and Discipline Manager. The Discipline Working Group of eminent scientists from outside of NASA acts in an advisory capacity and writes the Discipline Document from which the NRA content is derived. The program is reviewed approximately every three years by groups such as the Committee on Microgravity Research, the National Materials Advisory Board, and the OBPR Maximization and Prioritization (ReMaP) Task Force. The flight program has had as many as twenty-six principal investigators (PIs) in flight or flight definition stage, with the numbers of PIs in the future dependent on the results of the ReMaP Task Force and internal reviews. Each project has a NASA-appointed Project Scientist, considered a half-time job, who assists the PI in understanding and preparing for internal reviews such as the Science Concept Review and Requirements Definition Review. The Project Scientist also insures that the PI gets the maximum science support from MSFC, represents the PI to the MSFC community, and collaborates with the Project Manager to insure the project is well-supported and remains vital. Currently available flight equipment includes the Materials Science Research Rack (MSRR-1) and Microgravity Science Glovebox. Ground based projects fall into one or more of several categories. Intellectual Underpinning of Flight Program projects include theoretical studies backed by modeling and computer simulations; bring to maturity new research, often by young researchers, and may include preliminary short duration low gravity experiments in the KC-135 aircraft or drop tube; enable characterization of data sets from previous flights; and provide thermophysical property determinations to aid PIs. Radiation Shielding and preliminary In

  20. Housing Choice Voucher Program Support Division (PSD)

    Data.gov (United States)

    Department of Housing and Urban Development — Housing Choice Voucher (HCV) Program Management Programmatic Report for April to June 2010. This is inofrmation collected from Housing Authorities across the nation...

  1. Life sciences and environmental sciences

    Energy Technology Data Exchange (ETDEWEB)

    1992-02-01

    The DOE laboratories play a unique role in bringing multidisciplinary talents -- in biology, physics, chemistry, computer sciences, and engineering -- to bear on major problems in the life and environmental sciences. Specifically, the laboratories utilize these talents to fulfill OHER's mission of exploring and mitigating the health and environmental effects of energy use, and of developing health and medical applications of nuclear energy-related phenomena. At Lawrence Berkeley Laboratory (LBL) support of this mission is evident across the spectrum of OHER-sponsored research, especially in the broad areas of genomics, structural biology, basic cell and molecular biology, carcinogenesis, energy and environment, applications to biotechnology, and molecular, nuclear and radiation medicine. These research areas are briefly described.

  2. Life sciences and environmental sciences

    Energy Technology Data Exchange (ETDEWEB)

    1992-02-01

    The DOE laboratories play a unique role in bringing multidisciplinary talents -- in biology, physics, chemistry, computer sciences, and engineering -- to bear on major problems in the life and environmental sciences. Specifically, the laboratories utilize these talents to fulfill OHER`s mission of exploring and mitigating the health and environmental effects of energy use, and of developing health and medical applications of nuclear energy-related phenomena. At Lawrence Berkeley Laboratory (LBL) support of this mission is evident across the spectrum of OHER-sponsored research, especially in the broad areas of genomics, structural biology, basic cell and molecular biology, carcinogenesis, energy and environment, applications to biotechnology, and molecular, nuclear and radiation medicine. These research areas are briefly described.

  3. Development of Integrated Natural Science Teaching Materials Webbed Type with Applying Discourse Analysis on Students Grade VIII in Physics Class

    Science.gov (United States)

    Sukariasih, Luh

    2017-05-01

    This study aims to produce teaching materials integrated natural science (IPA) webbed type of handout types are eligible for use in integrated science teaching. This type of research IS a kind of research and development / Research and Development (R & D) with reference to the 4D development model that is (define, design, develop, and disseminate). Data analysis techniques used to process data from the results of the assessment by the validator expert, and the results of the assessment by teachers and learners while testing is limited (12 students of class VIII SMPN 10 Kendari) using quantitative descriptive data analysis techniques disclosed in the distribution of scores on the scale of five categories grading scale that has been determined. The results of due diligence material gain votes validator material in the category of “very good” and “good”, of the data generated in the feasibility test presentation obtained the category of “good” and “excellent”, from the data generated in the feasibility of graphic test obtained the category of “very good “and” good “, as well as of the data generated in the test the feasibility of using words and language obtained the category of“very good “and” good “, so with qualifications gained the teaching materials IPA integrated type webbed by applying discourse analysis on the theme of energy and food for Junior High School (SMP) grade VIII suitable as teaching materials. In limited testing, data generated in response to a science teacher at SMPN 10 Kendari to product instructional materials as “excellent”, and from the data generated while testing is limited by the 12 students of class VIII SMPN 10 Kendari are more students who score indicates category “very good”, so that the qualification obtained by the natural science (IPA) teaching material integrated type webbed by applying discourse analysis on the theme of energy and food for SMP / class VIII fit for use as teaching material.

  4. National Women's Science Congress

    Indian Academy of Sciences (India)

    TSC

    of Science, Engineering, Technology, Industrial Entrepreneurship and Management which will automatically empower ... The Science Congress would cover the entire spectrum of science, engineering and technology, ... Archaeology and Earth Sciences; (8) Ecology, Biodiversity, and Environment (9) Emerging. Frontier ...

  5. Science commons

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    SCP: Creative Commons licensing for open access publishing, Open Access Law journal-author agreements for converting journals to open access, and the Scholar's Copyright Addendum Engine for retaining rights to self-archive in meaningful formats and locations for future re-use. More than 250 science and technology journals already publish under Creative Commons licensing while 35 law journals utilize the Open Access Law agreements. The Addendum Engine is a new tool created in partnership with SPARC and U.S. universities. View John Wilbanks's biography

  6. Science Night

    CERN Multimedia

    2004-01-01

    Would it surprise you to know that you can measure the speed of light using chocolate and a microwave oven? If you're interested in this and in finding out much more, come along to the Museum of the History of Science on 3 and 4 July 2004, when dozens of companies, institutions, colleges and organizations will be running exhibits, shows, and displays on the theme of counting and measuring. CERN will be there with a display stand that includes two particle detectors. Full details are available from the Museum website at: http://www.lanuitdelascience.ch/

  7. Science blogging

    CERN Document Server

    Wilcox, Christie

    2016-01-01

    Here is the essential how-to guide for communicating scientific research and discoveries online, ideal for journalists, researchers, and public information officers looking to reach a wide lay audience. Drawing on the cumulative experience of twenty-seven of the greatest minds in scientific communication, this invaluable handbook targets the specific questions and concerns of the scientific community, offering help in a wide range of digital areas, including blogging, creating podcasts, tweeting, and more. With step-by-step guidance and one-stop expertise, this is the book every scientist, science writer, and practitioner needs to approach the Wild West of the Web with knowledge and confidence.

  8. Nanomaterials science

    Directory of Open Access Journals (Sweden)

    Heinrich Rohrer

    2010-01-01

    Full Text Available The nanometer regime covers the transition from condensed matter behavior to atomic and molecular properties and thus is a very rich but also very demanding area in materials science. Close to the condensed matter side, properties and functions might still very well be scalable, whereas close to the atomic and molecular side, the scalability is mostly lost. Properties and functions change qualitatively or quantitatively by orders of magnitude when the dimensions become smaller than a critical size in the nanometer range. Examples are the ballistic regime for electron or spin transport at dimensions below the mean free path, near-field effects in scanning near-field optical microscopy and quantum wells when the dimensions are below an appropriate wavelength, novel electronic, mechanical, and chemical properties when the number of bulk atoms becomes smaller than that of surface atoms, quantum conduction, and Coulomb blockade. Thus, by going below a certain size, an abundance of novel properties and functions are at one's disposal, or, in other words, we can functionalize materials simply by reducing their size to the nanoscale.The key to the future lies in the functions that we give to materials, not just in finding 'novel functional materials'. This catch expression in many materials science programs and initiatives of the past two decades sounds great, but it is not what really counts. All materials are functional in one way or another and, therefore, all new materials are 'novel functional materials'. Certainly, finding new materials is always an important part of progress, but we should also focus on the much larger domain of novel functions that we can give to existing or modified materials. A good example is semiconductors: they are fifty or more years old and their properties are very well known, but they were not of widespread interest and use until the transistor changed their destiny into being the central material in the information

  9. Do Gender-Science Stereotypes Predict Science Identification and Science Career Aspirations among Undergraduate Science Majors?

    Science.gov (United States)

    Cundiff, Jessica L.; Vescio, Theresa K.; Loken, Eric; Lo, Lawrence

    2013-01-01

    The present research examined whether gender-science stereotypes were associated with science identification and, in turn, science career aspirations among women and men undergraduate science majors. More than 1,700 students enrolled in introductory science courses completed measures of gender-science stereotypes (implicit associations and…

  10. Discovering indigenous science: Implications for science education

    Science.gov (United States)

    Snively, Gloria; Corsiglia, John

    2001-01-01

    Indigenous science relates to both the science knowledge of long-resident, usually oral culture peoples, as well as the science knowledge of all peoples who as participants in culture are affected by the worldview and relativist interests of their home communities. This article explores aspects of multicultural science and pedagogy and describes a rich and well-documented branch of indigenous science known to biologists and ecologists as traditional ecological knowledge (TEK). Although TEK has been generally inaccessible, educators can now use a burgeoning science-based TEK literature that documents numerous examples of time-proven, ecologically relevant, and cost effective indigenous science. Disputes regarding the universality of the standard scientific account are of critical importance for science educators because the definition of science is a de facto gatekeeping device for determining what can be included in a school science curriculum and what cannot. When Western modern science (WMS) is defined as universal it does displace revelation-based knowledge (i.e., creation science); however, it also displaces pragmatic local indigenous knowledge that does not conform with formal aspects of the standard account. Thus, in most science classrooms around the globe, Western modern science has been taught at the expense of indigenous knowledge. However, because WMS has been implicated in many of the world's ecological disasters, and because the traditional wisdom component of TEK is particularly rich in time-tested approaches that foster sustainability and environmental integrity, it is possible that the universalist gatekeeper can be seen as increasingly problematic and even counter productive. This paper describes many examples from Canada and around the world of indigenous people's contributions to science, environmental understanding, and sustainability. The authors argue the view that Western or modern science is just one of many sciences that need to be

  11. Learning Science with Science Fiction Films.

    Science.gov (United States)

    Cavanaugh, Terence; Cavanaugh, Catherine

    This paper is an excerpt from a book on learning science using science fiction. The focus is on the use of science fiction films to engage students and encourage greater enthusiasm and interest in science. "Jurassic Park" is used as an example that can provide educators with countless lesson opportunities. This approach recommends the use of fun…

  12. Science kitsch and pop science: A reconnaissance.

    Science.gov (United States)

    Kaeser, Eduard

    2013-07-01

    Science kitsch? The combination of these two words rings like an oxymoron. Science - as the common saying has it - exposes, discovers, tells the truth; kitsch conceals, covers, lies. I think, this "shadow" of science deserves a specific scrutiny, not only because it reflects the altered place and role of science in contemporary "knowledge" society but also because it pinpoints the task of relocating science in the "multicultural" context of postmodernism, with its different epistemic claims. The genre of science kitsch may help to regain credit by working as a probe to detect false pretensions, explanatory exuberance and exaggerations in science.

  13. 75 FR 10845 - Subcommittee on Forensic Science; Committee on Science; National Science and Technology Council

    Science.gov (United States)

    2010-03-09

    ... TECHNOLOGY POLICY Subcommittee on Forensic Science; Committee on Science; National Science and Technology... Subcommittee on Forensic Science of the National Science and Technology Council's (NSTC's) Committee on Science..., Subcommittee on Forensic Science. BILLING CODE 4410-FY-P ...

  14. Enacting science

    Science.gov (United States)

    MacDonald, Anthony Leo

    My study examines the development of forms of knowing that arise when students engage in open-ended explorations involving self-directed design and building involving simple materials. It is grounded in an enactivist theoretical perspective on cognition which holds that the creation of action-thought processes for engaging the world is interwoven with the meanings that are constructed for these experiences. A dynamic conception of persons-acting-in-a-setting is fundamental to an enactivist view of cognition. How is understanding enacted in building activity? How does the shape of a problem emerge? How do students enact meaning and understanding when they experience a high degree of physical engagement in building things? What are some characteristics of an enactive learning/teaching environment? My research settings comprise a range of individual, group and classroom engagements of varying lengths over a three and one-half year period. The first research episode involved two grade eight students in an investigation of Paper Towels. The second four month engagement was in a grade nine science class that culminated in the building of a Solar House. The third grade ten episode involved a one month project to build a Mousetrap Powered Car. A fourth Invent a Machine project was conducted in two grade eight science classes taught by the teacher who participated in the Solar House project. Two students were present in three of the four projects. I interviewed one of these students upon completion of his high school physics courses. I found that building is a form of thinking which develops competency in managing complex practical tasks. A triadic relationship of exploration, planning and acting is present. Practical and procedural understandings emerge as students enter and re-enter self-directed problem settings. Thinking patterns depend on the kinds of materials chosen, the ways they are used, and on how students contextualize the problem. Classroom assessment

  15. FOREWORD Nanomaterials science Nanomaterials science

    Science.gov (United States)

    Rohrer, Heinrich

    2010-10-01

    The nanometer regime covers the transition from condensed matter behavior to atomic and molecular properties and thus is a very rich but also very demanding area in materials science. Close to the condensed matter side, properties and functions might still very well be scalable, whereas close to the atomic and molecular side, the scalability is mostly lost. Properties and functions change qualitatively or quantitatively by orders of magnitude when the dimensions become smaller than a critical size in the nanometer range. Examples are the ballistic regime for electron or spin transport at dimensions below the mean free path, near-field effects in scanning near-field optical microscopy and quantum wells when the dimensions are below an appropriate wavelength, novel electronic, mechanical, and chemical properties when the number of bulk atoms becomes smaller than that of surface atoms, quantum conduction, and Coulomb blockade. Thus, by going below a certain size, an abundance of novel properties and functions are at one's disposal, or, in other words, we can functionalize materials simply by reducing their size to the nanoscale. The key to the future lies in the functions that we give to materials, not just in finding 'novel functional materials'. This catch expression in many materials science programs and initiatives of the past two decades sounds great, but it is not what really counts. All materials are functional in one way or another and, therefore, all new materials are 'novel functional materials'. Certainly, finding new materials is always an important part of progress, but we should also focus on the much larger domain of novel functions that we can give to existing or modified materials. A good example is semiconductors: they are fifty or more years old and their properties are very well known, but they were not of widespread interest and use until the transistor changed their destiny into being the central material in the information technology revolution

  16. Citizen Science

    Science.gov (United States)

    Memarsadeghi, Nargess

    2015-01-01

    Scientists and engineers constantly face new challenges, despite myriad advances in computing. More sets of data are collected today from earth and sky than there is time or resources available to carefully analyze them. Some problems either don't have fast algorithms to solve them or have solutions that must be found among millions of options, a situation akin to finding a needle in a haystack. But all hope is not lost: advances in technology and the Internet have empowered the general public to participate in the scientific process via individual computational resources and brain cognition, which isn't matched by any machine. Citizen scientists are volunteers who perform scientific work by making observations, collecting and disseminating data, making measurements, and analyzing or interpreting data without necessarily having any scientific training. In so doing, individuals from all over the world can contribute to science in ways that wouldn't have been otherwise possible.

  17. Supercomputational science

    CERN Document Server

    Wilson, S

    1990-01-01

    In contemporary research, the supercomputer now ranks, along with radio telescopes, particle accelerators and the other apparatus of "big science", as an expensive resource, which is nevertheless essential for state of the art research. Supercomputers are usually provided as shar.ed central facilities. However, unlike, telescopes and accelerators, they are find a wide range of applications which extends across a broad spectrum of research activity. The difference in performance between a "good" and a "bad" computer program on a traditional serial computer may be a factor of two or three, but on a contemporary supercomputer it can easily be a factor of one hundred or even more! Furthermore, this factor is likely to increase with future generations of machines. In keeping with the large capital and recurrent costs of these machines, it is appropriate to devote effort to training and familiarization so that supercomputers are employed to best effect. This volume records the lectures delivered at a Summer School ...

  18. Team science for science communication.

    Science.gov (United States)

    Wong-Parodi, Gabrielle; Strauss, Benjamin H

    2014-09-16

    Natural scientists from Climate Central and social scientists from Carnegie Mellon University collaborated to develop science communications aimed at presenting personalized coastal flood risk information to the public. We encountered four main challenges: agreeing on goals; balancing complexity and simplicity; relying on data, not intuition; and negotiating external pressures. Each challenge demanded its own approach. We navigated agreement on goals through intensive internal communication early on in the project. We balanced complexity and simplicity through evaluation of communication materials for user understanding and scientific content. Early user test results that overturned some of our intuitions strengthened our commitment to testing communication elements whenever possible. Finally, we did our best to negotiate external pressures through regular internal communication and willingness to compromise.

  19. Voodoo Science

    Science.gov (United States)

    Park, Robert

    2011-03-01

    A remarkable scientific result that appears to violate natural law may portend a revolutionary advance in human knowledge. It is, however, more likely an experimental screw up. Error is normal; it can be reduced by repeating measurements and better design of controls, but the success and credibility of science is anchored in a culture of openness. Ideas and observations are freely exposed to independent testing and evaluation by others. What emerges is the book of nature. On its pages we find, if not a simple world, at least an orderly world, in which everything from the birth of stars to falling in love is governed by the same natural laws. These laws cannot be circumvented by any amount of piety or cleverness, they can be understood - with the possible exception of String Theory. For those who elect to work outside the scientific community, errors may go unrecognized. We will examine examples of this, including claims of perpetual motion and cancer caused by cell-phone radiation.

  20. Life sciences.

    Science.gov (United States)

    Schmidt, Gregory K

    2002-12-01

    Space life sciences research activities are reviewed for the year. Highlights of animal studies were the first long-term flight of an animal enclosure module and an avian development facility on STS-108. Plant research efforts focused on a biomass production system for eventual use on the International Space Station (ISS), the PESTO experiment on ISS, and screening of several salad crop varieties for potential use in space. Health-related studies included the Martian Radiation Environment Experiment (MARIE) on the Mars Odyssey mission, presentation of results from NASA's Biomolecular Physics and Chemistry Program, and research related to human liver cell function in space through an agreement with StelSys. In industry and academia, a memorandum of understanding was signed between NASA and the biotechnology industry to enhance communication between NASA and the industry, expand commercial biotechnology space research and development, and expand formal and informal education of industry and the public regarding biotechnology and space research. NASA selected Purdue University to lead an NSCORT for advanced life support research to develop technologies to enable long-duration planetary mission and sustain human space colonies.

  1. JPRS Report, Science & Technology, USSR: Life Sciences

    National Research Council Canada - National Science Library

    1987-01-01

    Partial Contents: Aerospace Medicine, Agricultural Science, Biochemistry, Biophysics, Biotechnology, Epidemiology, Genetics, Immunology, Industrial Medicine, Laser Bioeffects, Marine Mammals, Medicine, Microbiology...

  2. JPRS Report Science & Technology USSR: Life Sciences

    National Research Council Canada - National Science Library

    1990-01-01

    Partial Contents: Agricultural Science, Biochemistry, Biophysics, Epidemiology, Genetics, Laser Bioeffects, Medicine, Microbiology, Molecular Biology, Nonionizing Radiation Effects, Physiology, Public Health...

  3. Cognitive science contributions to decision science.

    Science.gov (United States)

    Busemeyer, Jerome R

    2015-02-01

    This article briefly reviews the history and interplay between decision theory, behavioral decision-making research, and cognitive psychology. The review reveals the increasingly important impact that psychology and cognitive science have on decision science. One of the main contributions of cognitive science to decision science is the development of dynamic models that describe the cognitive processes that underlay the evolution of preferences during deliberation phase of making a decision. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Teaching Ethics in Science.

    Science.gov (United States)

    Reiss, Michael

    1999-01-01

    Summarizes arguments for and against teaching ethics within science education, and clarifies what might be the several aims of teaching ethics in science. Discusses how ethics instruction might be incorporated into the science curriculum. (Contains 120 references.) (WRM)

  5. Saturdays, Summer, and Science.

    Science.gov (United States)

    Zielinski, Edward J.; And Others

    1994-01-01

    Describes a science program (Saturday Science) designed to provide learning experiences that are thematic and stress critical/creative thinking as well as development of science process skills for elementary, middle, and junior high students. (ZWH)

  6. Common Earth Science Misconceptions in Science Teaching

    Science.gov (United States)

    King, Chris

    2012-01-01

    A survey of the Earth science content of science textbooks found a wide range of misconceptions. These are discussed in this article with reference to the published literature on Earth science misconceptions. Most misconceptions occurred in the "sedimentary rocks and processes" and "Earth's structure and plate tectonics"…

  7. Science + Maths = A Better Understanding of Science!

    Science.gov (United States)

    Markwick, Andy; Clark, Kris

    2016-01-01

    Science and mathematics share a common purpose: to explore, understand and explain the pure beauty of our universe and how it works. Using mathematics in science enquiry can enhance children's understanding of science and also provide opportunities for children to apply their mathematical knowledge to "real" contexts. The authors…

  8. Speaking of Science and for Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 12. Speaking of Science and for Science. G Baskaran. Article-in-a-Box Volume 7 Issue 12 December 2002 pp 47-47. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/007/12/0047-0047 ...

  9. Promoting science through science fiction and pseudoscience.

    Science.gov (United States)

    Roslund, C.

    1986-11-01

    A great deal of physics can be learned from reading good science fiction. Many writers of this genre have shown great talent in explaining the laws of physics in language that is both lucid and accessible. Their writings can readily be used by the science teacher to enhance and to stimulate student understanding of physics and science.

  10. What's science? Where's science? Science journalism in German print media.

    Science.gov (United States)

    Summ, Annika; Volpers, Anna-Maria

    2016-10-01

    This article examines the current state of science coverage in German print media. It deals with the following questions: (1) how the main characteristics of science journalism can be described, (2) whether there is a difference between various scientific fields, and (3) how different definitions of science journalism lead to differing findings. Two forms of science coverage were analyzed in a standardized, two-part content analysis of German newspapers (N = 1730 and N = 1640). The results show a significant difference between a narrow and a broad definition of science journalism. In the classic understanding, science journalism is prompted by scientific events and is rather noncritical. Science coverage in a broad sense is defined by a wider range of journalistic styles, driven by non-scientific events, and with a focus on the statements of scientific experts. Furthermore, the study describes the specific role of the humanities and social sciences in German science coverage. © The Author(s) 2015.

  11. Science Olympiad students' nature of science understandings

    Science.gov (United States)

    Philpot, Cindy J.

    2007-12-01

    Recent reform efforts in science education focus on scientific literacy for all citizens. In order to be scientifically literate, an individual must have informed understandings of nature of science (NOS), scientific inquiry, and science content matter. This study specifically focused on Science Olympiad students' understanding of NOS as one piece of scientific literacy. Research consistently shows that science students do not have informed understandings of NOS (Abd-El-Khalick, 2002; Bell, Blair, Crawford, and Lederman, 2002; Kilcrease and Lucy, 2002; Schwartz, Lederman, and Thompson, 2001). However, McGhee-Brown, Martin, Monsaas and Stombler (2003) found that Science Olympiad students had in-depth understandings of science concepts, principles, processes, and techniques. Science Olympiad teams compete nationally and are found in rural, urban, and suburban schools. In an effort to learn from students who are generally considered high achieving students and who enjoy science, as opposed to the typical science student, the purpose of this study was to investigate Science Olympiad students' understandings of NOS and the experiences that formed their understandings. An interpretive, qualitative, case study method was used to address the research questions. The participants were purposefully and conveniently selected from the Science Olympiad team at a suburban high school. Data collection consisted of the Views of Nature of Science -- High School Questionnaire (VNOS-HS) (Schwartz, Lederman, & Thompson, 2001), semi-structured individual interviews, and a focus group. The main findings of this study were similar to much of the previous research in that the participants had informed understandings of the tentative nature of science and the role of inferences in science, but they did not have informed understandings of the role of human imagination and creativity, the empirical nature of science, or theories and laws. High level science classes and participation in

  12. Connecting Science and Technology

    Science.gov (United States)

    Pleasants, Jacob

    2017-01-01

    Helping students understand the Nature of Science (NOS) is a long-standing goal of science education. One method is to provide students examples of science history in the form of short stories. This article modifies that approach, using historical case studies to address both the history of science and the history of technology, as well as the…

  13. Science Fiction & Scientific Literacy

    Science.gov (United States)

    Czerneda, Julie E.

    2006-01-01

    The term "science fiction" has become synonymous, in the media at least, for any discovery in science too incredible or unexpected for the nonscientist to imagine. One of the most common classroom uses of science fiction is for students to pick out flaws in science fiction movies or television shows. Unfortunately, this approach can result in…

  14. Science & Engineering Indicators--1989.

    Science.gov (United States)

    National Science Foundation, Washington, DC. National Science Board.

    This volume is the ninth in the biennial "Science Indicators" series initiated by the National Science Board. The series provides a broad base of quantitative information about the structure and function of United States science and technology and comparisons with other advanced industrial countries. An overview of science and technology…

  15. Project-Based Science

    Science.gov (United States)

    Krajcik, Joe

    2015-01-01

    Project-based science is an exciting way to teach science that aligns with the "Next Generation Science Standards" ("NGSS"). By focusing on core ideas along with practices and crosscutting concepts, classrooms become learning environments where teachers and students engage in science by designing and carrying out…

  16. Pragmaticism, Science and Theology

    DEFF Research Database (Denmark)

    Brier, Søren

    2016-01-01

    This review assesses Ashley and Deely’s claims regarding the relation of science and religion, taking Einstein’s famous statement that “science without religion is lame, religion without science is blind” as its starting point. It argues that Ashley and Deely’s book How Science Enriches Theology...

  17. Science to the People

    CERN Document Server

    Doswaldbeck, L; Brancati, D; Colombo, U; Coyaud, S; De Semir, V; Dupuy, G; Ellis, Jonathan Richard; Lecourt, D; Llewellyn Smith, Christopher Hubert; Mettan, G; Montagnier, L; Morrison, Douglas Robert Ogston; Rampini, F; Ting, Samuel C C; Ugo, R; Widman, A; CERN. Geneva

    1994-01-01

    Science & society : urgent topics Risk perception : Ringing the alarm bells Basic research : Understanding its relevance Science and Economics : Comparing puplic costs and puplic benefits Language(s) : Translating expert knowledge into common culture Science and ethics : Freedom of research and limits to its applications Science,Media & Society: A confrontation

  18. Learning Science Process Through Data Exploration and Writing

    Science.gov (United States)

    Prothero, W. A.

    2007-12-01

    One of the most effective ways of teaching science process is to have students take part in the same activities that practicing scientists engage in. These activities include studying the current research in the field, discussing ideas with colleagues, formulating a research problem, making a proposal defining the problem and plan of attack, presenting and writing about the results of the study, and critically reviewing the work of others. An inquiry curriculum can use these activities to guide the scaffolding of assignments and learning experiences that help students learn science process. At UCSB, students in a large general education oceanography class use real Earth data to study plate tectonics, the Indian Monsoon, climate change, and the health of the world fisheries. The end product for each subject has been a science paper based on Earth data. Over a period of approximately 15 years, the scaffolding of activities to prepare each student for the written assignments has been modified and improved, in response to student feedback and their success with the assignments. I have found that the following resources and sequence of activities help the oceanography students write good science papers. 1. Lecture: motivation and the opportunity for feedback and questions. 2. Textbook: background information. It is also possible to get the information from the internet, but unless the scope of reading is strictly defined, students don't know when to stop reading and become unhappy. 3. Online assignments: automatically graded assignments that force the student to keep up with reading. 4. Questions of the day: in-class handouts, with diagrams that the students either complete, or answer questions about. They are handed in and tallied, but not graded. They also inform the instructor of misconceptions. 5. Thought questions: student answers are posted on a threaded discussion list, and are due prior to lecture. The answers provide instructor feedback and guide the lecture

  19. Science in Cinema. Teaching Science Fact through Science Fiction Films.

    Science.gov (United States)

    Dubeck, Leroy W.; And Others

    Many feel that secondary school graduates are not prepared to compete in a world of rapidly expanding technology. High school and college students in the United States often prefer fantasy to science. This book offers a strategy for overcoming student apathy toward the physical sciences by harnessing the power of the cinema. In it, ten popular…

  20. A mirror for science.

    Science.gov (United States)

    Jasanoff, Sheila

    2014-01-01

    Early conceptions of the public understanding of science suffered from a narrow framing of what science means and a presumption that science is divided from its publics by walls of ignorance and indifference. Those assumptions amplified misunderstanding and led to faulty policies. It is time to reopen each element in the term "public understanding of science" to renewed reflection. This journal can advance that goal by encouraging research on actual rather than imagined public responses to science, on representations of science in the public sphere, and on interactions between science, technology and society.

  1. Holography: science and art

    Science.gov (United States)

    Boone, Pierre M.

    1998-09-01

    Art and science are separated by a very large distance nowadays. Long ago, e.g. in Renaissance, or even earlier, in classic Greece and Rome, or still earlier in Egypt or Mesopotamia, arts and sciences were united. Today they seem to go separate paths: science for the industry, arts for the gallery. Holography is an exception: no art without science, but also no science without art.

  2. The Communication of Science

    OpenAIRE

    Fan, Yuzhou; Cong, Zhiyuan; Haugaard, Anastasiya; Kelder, Yonatan

    2006-01-01

    In science, the natural science is being used to study the nature surrounding us. As a rule, the methods of natural science are based on strong scientific evidence that would either prove or disprove the scientific hypothesis. Therefore, the natural science is considered to be pretty much unilateral; there is very little uncertainty within the evidence of natural science. Doing this project has taught us the opposite. The basic semester requirement is to write a project “about science” and...

  3. Science Operations for Onboard Autonomous Rover Science

    Science.gov (United States)

    Estlin, T.; Castano, R.; Haldemann, A. F.; McHenry, M.; Bornstein, B.; Gaines, D.; Burl, M.; Anderson, R. C.; Powell, M.; Shu, I.; Farr, T.; Nesnas, I.; Jain, A.; Judd, M.

    2006-12-01

    Onboard autonomous science represents one means to balance the large amounts of scientific data that current and future rovers can acquire with the limited ability to download it to Earth. Several systems are under development to perform autonomous rover science. The use of such systems represents a departure from standard operations, which closely resemble batch tele-operation. It is important for the science operations team to understand the capabilities and limitations of the onboard system to effectively use the tool of autonomous onboard science to increase overall mission science return, however it is difficult for the science team to get a feel for the onboard system without hands on experience in an operational system setting. This past year, the OASIS (Onboard Autonomous Science Investigation System) team has been working with the SOOPS (Science Operations On Planetary Surfaces) task to investigate how science returns for surface missions can be improved through the use of science autonomy. A limited version of OASIS was tested at the system level. The test involved a high-fidelity software simulation of a rover exploring a remote terrain using realistic operational interfaces. By using the simulation environment it is feasible to run many more experiments than testing with physical rover. Further, the simulation environment combined with the integrated operational system provides situational awareness for the science operations team along with greater flexibility and control over experiments to help answer "what if" questions that can lead to identifying the most effective ways to use the onboard system. In the tests, OASIS applied predetermined criteria provided by the scientists to prioritize which data collected during a traverse to send home, given specified bandwidth constraints. In addition, rock summary information (which requires very little bandwidth) was returned and provided as both a table and a map to the science team. We discuss the results

  4. The World of Science Fiction.

    Science.gov (United States)

    Schwartz, Sheila

    1971-01-01

    Science fiction is discussed from the following standpoints: What Is Science Fiction?; The History of Science Fiction; and The Themes of Science Fiction. A list of films, books, and records about science fiction is given. (DB)

  5. A Science Cloud for Data Intensive Sciences

    Directory of Open Access Journals (Sweden)

    Ken T Murata

    2013-03-01

    Full Text Available It is often discussed that the fourth methodology for science research is "informatics". The first methodology is a theoretic approach, the second one is observation and/or experiment, and the third one is computer simulation. Informatics is a new methodology for data intensive science, which is a new concept based on the fact that most scientific data are digitalized and the amount of data is huge. The facilities to support informatics are cloud systems. Herein we propose a cloud system especially designed for science. The basic concepts, design, resources, implementation, and applications of the NICT science cloud are discussed.

  6. Network science, nonlinear science and infrastructure systems

    CERN Document Server

    2007-01-01

    Network Science, Nonlinear Science and Infrastructure Systems has been written by leading scholars in these areas. Its express purpose is to develop common theoretical underpinnings to better solve modern infrastructural problems. It is felt by many who work in these fields that many modern communication problems, ranging from transportation networks to telecommunications, Internet, supply chains, etc., are fundamentally infrastructure problems. Moreover, these infrastructure problems would benefit greatly from a confluence of theoretical and methodological work done with the areas of Network Science, Dynamical Systems and Nonlinear Science. This book is dedicated to the formulation of infrastructural tools that will better solve these types of infrastructural problems. .

  7. A Self-Help Handout for Benzodiazepine Discontinuation Using Cognitive Behavioral Therapy

    Science.gov (United States)

    Ahmed, Mariyam; Westra, Henry A.; Stewart, Sherry H.

    2008-01-01

    Although prescription rates may be declining, benzodiazepines (BZs) are still very commonly prescribed for the treatment of anxiety disorders. Because many anxiety patients require assistance in successfully discontinuing BZs, cognitive behavioral therapy (CBT) approaches have been specifically developed to target this issue, and an evidence base…

  8. MATERIALS FOR CIVIL ENGINEERING: A HANDOUT FOR QUICK CONSULTATION FOR THE CHOICE OF BETTER MATERIAL

    OpenAIRE

    Moura, Guilherme Ribeiro de; Uzelotto, Felipe Ribeiro; Teixeira, Thaise Moser

    2013-01-01

    Current research analyzes the best materials for civil engineering in Maringá PR Brazil. Experienced-based analysis comprises information by engineers and architects on the performance of different types of material with regard to their resistance in the structural composition of a building. Following the experience of professionals in Maringá, several building materials assessed comprised structural concrete, structural and conventional masonry, steel, plywood and wood, in this order. Engine...

  9. The Impact of Childhood Trauma on Brain Development: A Literature Review and Supporting Handouts

    Science.gov (United States)

    Kirouac, Samantha; McBride, Dawn Lorraine

    2009-01-01

    This project provides a comprehensive overview of the research literature on the brain and how trauma impacts brain development, structures, and functioning. A basic exploration of childhood trauma is outlined in this project, as it is essential in making associations and connections to brain development. Childhood trauma is processed in the…

  10. Empirical philosophy of science

    DEFF Research Database (Denmark)

    Wagenknecht, Susann; Nersessian, Nancy J.; Andersen, Hanne

    2015-01-01

    A growing number of philosophers of science make use of qualitative empirical data, a development that may reconfigure the relations between philosophy and sociology of science and that is reminiscent of efforts to integrate history and philosophy of science. Therefore, the first part...... of this introduction to the volume Empirical Philosophy of Science outlines the history of relations between philosophy and sociology of science on the one hand, and philosophy and history of science on the other. The second part of this introduction offers an overview of the papers in the volume, each of which...

  11. NX15 science workshop

    CERN Multimedia

    2015-01-01

    Science. For some of us, it's daunting or maybe even terrifying. How to tell a good science story? That's the question we will explore together in this workshop. Conceived and produced by journalist and Scientific News producer Claudio Rosmino of Euronews, and presented by Euronews' Jeremy Wilks, the workshop will look at actual case studies (from Euronews and beyond) where science news proved exciting, inspiring and accessible to audiences around the world. These might include the Rosetta mission and CERN's work on Science for Peace. Together, we'll share ideas and knowledge around how science journalism and science news can increase its visibility in the media and maybe save the planet...!

  12. Towards Data Science

    Directory of Open Access Journals (Sweden)

    Yangyong Zhu

    2015-05-01

    Full Text Available Currently, a huge amount of data is being rapidly generated in cyberspace. Datanature (all data in cyberspace is forming due to a data explosion. Exploring the patterns and rules in datanature is necessary but difficult. A new discipline called Data Science is coming. It provides a type of novel research method (a data-intensive method for natural and social sciences and goes beyond computer science in researching data. This paper presents the challenges presented by data and discusses what differentiates data science from the established sciences, data technologies, and big data. Our goal is to encourage data related researchers to transfer their focus towards this new science.

  13. CSIR ScienceScope: Life sciences

    CSIR Research Space (South Africa)

    CSIR

    2007-04-01

    Full Text Available , manage our unique and fragile ecosystems, and find more sustainable energy alternatives. This edition of ScienceScope features some CSIR research outcomes in life sciences achieved to date, while outlining current and future objectives. L I F E SC...

  14. Women in Science : A Career in Science

    Indian Academy of Sciences (India)

    user

    not appear that there is a societal perception in India of women being incapable of intellectual attainment in science since women students are not in short supply at the under-graduate and post-graduate levels in science. ... Transport, congestion and traps in a communication network. Department of Physics, IIT, Madras.

  15. Teaching Science Fact with Science Fiction

    Science.gov (United States)

    Raham, R. Gary

    2004-01-01

    The literature of science fiction packs up the facts and discoveries of science and runs off to futures filled with both wonders and warnings. Kids love to take the journeys it offers for the thrill of the ride, but they can learn as they travel, too. This book will provide the reader with: (1) an overview of the past 500 years of scientific…

  16. Democratizing data science through data science training.

    Science.gov (United States)

    Van Horn, John Darrell; Fierro, Lily; Kamdar, Jeana; Gordon, Jonathan; Stewart, Crystal; Bhattrai, Avnish; Abe, Sumiko; Lei, Xiaoxiao; O'Driscoll, Caroline; Sinha, Aakanchha; Jain, Priyambada; Burns, Gully; Lerman, Kristina; Ambite, José Luis

    2018-01-01

    The biomedical sciences have experienced an explosion of data which promises to overwhelm many current practitioners. Without easy access to data science training resources, biomedical researchers may find themselves unable to wrangle their own datasets. In 2014, to address the challenges posed such a data onslaught, the National Institutes of Health (NIH) launched the Big Data to Knowledge (BD2K) initiative. To this end, the BD2K Training Coordinating Center (TCC; bigdatau.org) was funded to facilitate both in-person and online learning, and open up the concepts of data science to the widest possible audience. Here, we describe the activities of the BD2K TCC and its focus on the construction of the Educational Resource Discovery Index (ERuDIte), which identifies, collects, describes, and organizes online data science materials from BD2K awardees, open online courses, and videos from scientific lectures and tutorials. ERuDIte now indexes over 9,500 resources. Given the richness of online training materials and the constant evolution of biomedical data science, computational methods applying information retrieval, natural language processing, and machine learning techniques are required - in effect, using data science to inform training in data science. In so doing, the TCC seeks to democratize novel insights and discoveries brought forth via large-scale data science training.

  17. Science & Engineering Indicators 2016. National Science Board

    Science.gov (United States)

    National Science Foundation, 2016

    2016-01-01

    "Science and Engineering Indicators" (SEI) is first and foremost a volume of record comprising high-quality quantitative data on the U.S. and international science and engineering enterprise. SEI includes an overview and seven chapters that follow a generally consistent pattern. The chapter titles are as follows: (1) Elementary and…

  18. Advancing the Science of Team Science

    Science.gov (United States)

    Falk‐Krzesinski, Holly J.; Börner, Katy; Contractor, Noshir; Fiore, Stephen M.; Hall, Kara L.; Keyton, Joann; Spring, Bonnie; Stokols, Daniel; Trochim, William; Uzzi, Brian

    2010-01-01

    Abstract The First Annual International Science of Team Science (SciTS) Conference was held in Chicago, IL April 22–24, 2010. This article presents a summary of the Conference proceedings. Clin Trans Sci 2010; Volume 3: 263–266. PMID:20973925

  19. Analogies in Science and Science Teaching

    Science.gov (United States)

    Brown, Simon; Salter, Susan

    2010-01-01

    Analogies are often used in science, but students may not appreciate their significance, and so the analogies can be misunderstood or discounted. For this reason, educationalists often express concern about the use of analogies in teaching. Given the important place of analogies in the discourse of science, it is necessary that students are…

  20. Science and religion: implications for science educators

    Science.gov (United States)

    Reiss, Michael J.

    2010-03-01

    A religious perspective on life shapes how and what those with such a perspective learn in science; for some students a religious perspective can hinder learning in science. For such reasons Staver's article is to be welcomed as it proposes a new way of resolving the widely perceived discord between science and religion. Staver notes that Western thinking has traditionally postulated the existence and comprehensibility of a world that is external to and independent of human consciousness. This has led to a conception of truth, truth as correspondence, in which our knowledge corresponds to the facts in this external world. Staver rejects such a conception, preferring the conception of truth as coherence in which the links are between and among independent knowledge claims themselves rather than between a knowledge claim and reality. Staver then proposes constructivism as a vehicle potentially capable of resolving the tension between religion and science. My contention is that the resolution between science and religion that Staver proposes comes at too great a cost—both to science and to religion. Instead I defend a different version of constructivism where humans are seen as capable of generating models of reality that do provide richer and more meaningful understandings of reality, over time and with respect both to science and to religion. I argue that scientific knowledge is a subset of religious knowledge and explore the implications of this for science education in general and when teaching about evolution in particular.

  1. Informal science education at Science City

    Science.gov (United States)

    French, April Nicole

    The presentation of chemistry within informal learning environments, specifically science museums and science centers is very sparse. This work examines learning in Kansas City's Science City's Astronaut Training Center in order to identify specific behaviors associated with visitors' perception of learning and their attitudes toward space and science to develop an effective chemistry exhibit. Grounded in social-constructivism and the Contextual Model of Learning, this work approaches learning in informal environments as resulting from social interactions constructed over time from interaction between visitors. Visitors to the Astronaut Training Center were surveyed both during their visit and a year after the visit to establish their perceptions of behavior within the exhibit and attitudes toward space and science. Observations of visitor behavior and a survey of the Science City staff were used to corroborate visitor responses. Eighty-six percent of visitors to Science City indicated they had learned from their experiences in the Astronaut Training Center. No correlation was found between this perception of learning and visitor's interactions with exhibit stations. Visitor attitudes were generally positive toward learning in informal settings and space science as it was presented in the exhibit. Visitors also felt positively toward using video game technology as learning tools. This opens opportunities to developing chemistry exhibits using video technology to lessen the waste stream produced by a full scale chemistry exhibit.

  2. Physical Sciences 2007 Science & Technology Highlights

    Energy Technology Data Exchange (ETDEWEB)

    Hazi, A U

    2008-04-07

    The Physical Sciences Directorate applies frontier physics and technology to grand challenges in national security. Our highly integrated and multidisciplinary research program involves collaborations throughout Lawrence Livermore National Laboratory, the National Nuclear Security Administration, the Department of Energy, and with academic and industrial partners. The Directorate has a budget of approximately $150 million, and a staff of approximately 350 employees. Our scientists provide expertise in condensed matter and high-pressure physics, plasma physics, high-energy-density science, fusion energy science and technology, nuclear and particle physics, accelerator physics, radiation detection, optical science, biotechnology, and astrophysics. This document highlights the outstanding research and development activities in the Physical Sciences Directorate that made news in 2007. It also summarizes the awards and recognition received by members of the Directorate in 2007.

  3. Big Science, Team Science, and Open Science for Neuroscience.

    Science.gov (United States)

    Koch, Christof; Jones, Allan

    2016-11-02

    The Allen Institute for Brain Science is a non-profit private institution dedicated to basic brain science with an internal organization more commonly found in large physics projects-large teams generating complete, accurate and permanent resources for the mouse and human brain. It can also be viewed as an experiment in the sociology of neuroscience. We here describe some of the singular differences to more academic, PI-focused institutions. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. AAAS: Politics. . . and Science

    Science.gov (United States)

    Science News, 1978

    1978-01-01

    Reviews topics discussed during the American Association for the Advancement of Science (AAAS) meeting held in Washington, D.C. Topics included: the equal rights amendment, laetrile, nuclear radiation hazards, sociobiology, and various science topics. (SL)

  5. Science of landscape restoration

    CSIR Research Space (South Africa)

    De Wet, Benita

    2011-11-01

    Full Text Available or email bdewet@ csir.co.za. The science of landscape restoration Over the last two decades the ecological restoration of industrial land has developed into a specialist science combined with highly sophisticated management activities. A prime...

  6. Science and Shakespeare.

    Science.gov (United States)

    Mah, Steven; Chinnery, Charlene

    2003-01-01

    Describes an assignment in which the preservice teacher must find a connection between science and Shakespeare. Connects the science of the witches in Shakespeare's "Macbeth" to the holistic approach of education. (SG)

  7. Integrating Forensic Science.

    Science.gov (United States)

    Funkhouser, John; Deslich, Barbara J.

    2000-01-01

    Explains the implementation of forensic science in an integrated curriculum and discusses the advantages of this approach. Lists the forensic science course syllabi studied in three high schools. Discusses the unit on polymers in detail. (YDS)

  8. ICASE Computer Science Program

    Science.gov (United States)

    1985-01-01

    The Institute for Computer Applications in Science and Engineering computer science program is discussed in outline form. Information is given on such topics as problem decomposition, algorithm development, programming languages, and parallel architectures.

  9. Science Inventory | US EPA

    Science.gov (United States)

    The Science Inventory is a searchable database of research products primarily from EPA's Office of Research and Development. Science Inventory records provide descriptions of the product, contact information, and links to available printed material or websites.

  10. National Academy of Sciences

    Science.gov (United States)

    ... Programs Distinctive Voices Lecture Series Science & Entertainment Exchange Evolution Resources Biographical Memoirs National Academy of Sciences About The NAS Mission History Organization Leadership and Governance Membership Policy Studies and Reports Giving ...

  11. Inequalities in Science

    OpenAIRE

    Xie, Y.

    2014-01-01

    Inequalities in scientists’ contributions to science and their rewards have always been very high. There are good reasons to propose that inequalities in science across research institutions and across individual scientists have increased in recent years. In the meantime, however, globalization and internet technology have narrowed inequalities in science across nations and facilitated the expansion of science and rapid production of scientific discoveries through international collaborative ...

  12. Social science that matters

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2006-01-01

    Social science is headed down a dead end toward mere scientism, becoming a second-rate version of the hard sciences. We neeed to recognise and support a different kind of social science research - and so should those who demand accountability from researchers. This paper asks what kind of social...... science we - scholars, policy makers, administrators - should and should not promote in democratic societies, and how we may hold social scientists accountable to deliver what we ask them for....

  13. Inequalities in Science

    Science.gov (United States)

    Xie, Y.

    2014-01-01

    Inequalities in scientists’ contributions to science and their rewards have always been very high. There are good reasons to propose that inequalities in science across research institutions and across individual scientists have increased in recent years. In the meantime, however, globalization and internet technology have narrowed inequalities in science across nations and facilitated the expansion of science and rapid production of scientific discoveries through international collaborative networks. PMID:24855244

  14. Traveling science: An elementary science enhancement program

    Energy Technology Data Exchange (ETDEWEB)

    Gotlib, L.; Brown, S. [South Granvile High School, Creedmoor, NC (United States); Bibby, E. [Granville County Schools, Oxford, NC (United States)

    1994-12-31

    Traveling Science is an elementary science visitation program by two high school teachers (using scheduled release time) for every third to fifth grade student and teacher in Granville County, North Carolina (a total of sixty-one classes, 1,600 students-over 25,000 student contacts in three years). Teachers and students see and participate in hands-on, inquiry-based science done with inexpensive, readily available materials (usually less than 2% per class). Teachers become more confident and self-reliant with respect to science education, and students get increased exposure to hands-on science. In addition to the classroom visits (a total of six per year for each class), teachers receive a guide containing introductory and follow-up materials, and a monthly newsletter. Visit topics cover the physical, life and earth sciences; designed to stress the processes of science. We try to use topics of interest and relevance to students, such as toys, food, animals and playground activities. Teachers and schools also receive additional materials (posters and videos).

  15. African Health Sciences

    African Journals Online (AJOL)

    African Health Sciences is an open access, free online, internationally refereed journal publishing original articles on research, clinical practice, public health, policy, planning, implementation and evaluation, in the health and related sciences relevant to Africa and the tropics. African Health Sciences acknowledges support ...

  16. But Is It Science?

    Science.gov (United States)

    Watts, Mike; Salehjee, Saima; Essex, Jane

    2017-01-01

    Early years science education is not science, but a curricular construction designed to induct young children into a range of ideas and practices related to the natural world. While inquiry-based learning is an important approach to this, it is not of itself unique to science and there are a range of logico-mathematical constructions that come…

  17. Emotionally Intense Science Activities

    Science.gov (United States)

    King, Donna; Ritchie, Stephen; Sandhu, Maryam; Henderson, Senka

    2015-01-01

    Science activities that evoke positive emotional responses make a difference to students' emotional experience of science. In this study, we explored 8th Grade students' discrete emotions expressed during science activities in a unit on Energy. Multiple data sources including classroom videos, interviews and emotion diaries completed at the end of…

  18. Science Comic Strips

    Science.gov (United States)

    Kim, Dae Hyun; Jang, Hae Gwon; Shin, Dong Sun; Kim, Sun-Ja; Yoo, Chang Young; Chung, Min Suk

    2012-01-01

    Science comic strips entitled Dr. Scifun were planned to promote science jobs and studies among professionals (scientists, graduate and undergraduate students) and children. To this end, the authors collected intriguing science stories as the basis of scenarios, and drew four-cut comic strips, first on paper and subsequently as computer files.…

  19. Computers in Science Fiction.

    Science.gov (United States)

    Kurland, Michael

    1984-01-01

    Science fiction writers' perceptions of the "thinking machine" are examined through a review of Baum's Oz books, Heinlein's "Beyond This Horizon," science fiction magazine articles, and works about robots including Asimov's "I, Robot." The future of computers in science fiction is discussed and suggested readings are listed. (MBR)

  20. Science on Wheels

    Science.gov (United States)

    Savitz, Maxine L.

    1973-01-01

    A science program was developed which is based on a mobile laboratory containing scientific experiments in biology, chemistry, physics, applied science, and mathematics. Discussion and experiments differ from the normal classroom setting as they utilize small groups and center around the relationship of modern science and technology of the urban…

  1. Sci-Fi Science.

    Science.gov (United States)

    Freudenrich, Craig C.

    2000-01-01

    Recommends using science fiction television episodes, novels, and films for teaching science and motivating students. Studies Newton's Law of Motion, principles of relativity, journey to Mars, interplanetary trajectories, artificial gravity, and Martian geology. Discusses science fiction's ability to capture student interest and the advantages of…

  2. Forensic Science Technician

    Science.gov (United States)

    Tech Directions, 2010

    2010-01-01

    Forensic science technicians, also called crime laboratory technicians or police science technicians, help solve crimes. They examine and identify physical evidence to reconstruct a crime scene. This article discusses everything students need to know about careers for forensic science technicians--wages, responsibilities, skills needed, career…

  3. Agricultural science and ethics

    DEFF Research Database (Denmark)

    Gjerris, Mickey; Vaarst, Mette

    2014-01-01

    , about 20 % of the world's coral reefs and 35 % of the mangrove areas were lost (Millennium Ecosystem Assessment 2005). In the following, the development of agricultural science will be sketched out and the role of ethics in agricultural science will be discussed. Then different views of nature that have...... between agricultural science and ethics....

  4. Social Work and Science

    Science.gov (United States)

    Gehlert, Sarah

    2016-01-01

    Interest has grown in the past few years about the place of social work in science. Questions remain, such as whether social work should be considered a science, and if so, where it fits into the constellation of sciences. This article attempts to shed light on these questions. After briefly considering past and present constructions of science…

  5. Science and Human Experience

    Science.gov (United States)

    Cooper, Leon N.

    2015-01-01

    Part I. Science and Society: 1. Science and human experience; 2. Does science undermine our values?; 3. Can science serve mankind?; 4. Modern science and contemporary discomfort: metaphor and reality; 5. Faith and science; 6. Art and science; 7. Fraud in science; 8. Why study science? The keys to the cathedral; 9. Is evolution a theory? A modest proposal; 10. The silence of the second; 11. Introduction to Copenhagen; 12. The unpaid debt; Part II. Thought and Consciousness: 13. Source and limits of human intellect; 14. Neural networks; 15. Thought and mental experience: the Turing test; 16. Mind as machine: will we rubbish human experience?; 17. Memory and memories: a physicist's approach to the brain; 18. On the problem of consciousness; Part III. On the Nature and Limits of Science: 19. What is a good theory?; 20. Shall we deconstruct science?; 21. Visible and invisible in physical theory; 22. Experience and order; 23. The language of physics; 24. The structure of space; 25. Superconductivity and other insoluble problems; 26. From gravity to light and consciousness: does science have limits?

  6. Super Science Fair Sourcebook.

    Science.gov (United States)

    Iritz, Maxine Haren

    This guide to science fair projects is designed for students and provides clear directions on how to complete a successful science project. Real projects are used as examples and information and advice is provided by teachers, judges, and participants and their families about the process. Topics covered in this book include choosing a science fair…

  7. Science Challenge Day

    Science.gov (United States)

    Siegel, Deborah

    2013-01-01

    Science fairs can be good motivators, but as extracurricular activities, they leave some students behind. However, by staging a Science Challenge Day at school, educators can involve all students in doing everything from choosing activities to judging projects. This article presents a model for running a successful Science Challenge Day. The…

  8. Fundamentals of soil science

    Science.gov (United States)

    This study guide provides comments and references for professional soil scientists who are studying for the soil science fundamentals exam needed as the first step for certification. The performance objectives were determined by the Soil Science Society of America's Council of Soil Science Examiners...

  9. African Crop Science Journal

    African Journals Online (AJOL)

    The African Crop Science Journal, a quarterly publication, publishes original research papers dealing with all aspects of crop agronomy, production, genetics and breeding, germplasm, crop protection, post harvest systems and utilisation, agro-forestry, crop-animal interactions, information science, environmental science ...

  10. Information science in transition

    CERN Document Server

    Gilchrist, Alan

    2013-01-01

    Are we at a turning point in digital information? The expansion of the internet is unprecedented. Will information science become part of computer science and does rise of the term informatics demonstrate convergence of information science and information technology - a convergence that must surely develop? This work reflects on such issues.

  11. Science and Literacy Centers

    Science.gov (United States)

    Van Meeteren, Beth Dykstra; Escalada, Lawrence T.

    2010-01-01

    In recent years, science has taken a backseat to reading and mathematics in many primary classrooms. Imaginative teachers have coped with this loss of science time by creatively integrating science topics into reading instructional materials (Douglas, Klentschy, and Worth 2006). In this article, the author describes an effective physical science…

  12. Demystifying Nature of Science

    Science.gov (United States)

    Lederman, Judith; Bartels, Selina; Lederman, Norman; Gnanakkan, Dionysius

    2014-01-01

    With the emergence of the "Next Generation Science Standards" ("NGSS"; NGSS Lead States 2013), it is apparent that teaching and learning about nature of science (NOS) continues to be an important goal of science education for all K-12 students. With this emphasis on NOS, early childhood teachers are asking how to design…

  13. 75 FR 4882 - Subcommittee on Forensic Science; Committee on Science; National Science and Technology Council

    Science.gov (United States)

    2010-01-29

    ... TECHNOLOGY POLICY Subcommittee on Forensic Science; Committee on Science; National Science and Technology... Executive Branch responses to the National Academy of Sciences 2009 report: ``Strengthening Forensic Science... ). SUMMARY: The Subcommittee on Forensic Science (SOFS) of the National Science and Technology Council's...

  14. New Science on the Open Science Grid

    CERN Document Server

    Board, The Open Science Grid Executive; Pordes, Ruth; Altunay, Mine; Avery, Paul; Bejan, Alina; Blackburn, Kent; Blatecky, Alan; Gardner, Rob; Kramer, Bill; Livny, Miron; McGee, John; Potekhin, Maxim; Quick, Rob; Olson, Doug; Roy, Alain; Sehgal, Chander; Wenaus, Torre; Wilde, Mike; Wuerthwein, Frank

    2012-01-01

    The Open Science Grid (OSG) includes work to enable new science, new scientists, and new modalities in support of computationally based research. There are frequently significant sociological and organizational changes required in transformation from the existing to the new. OSG leverages its deliverables to the large scale physics experiment member communities to benefit new communities at all scales through activities in education, engagement and the distributed facility. As a partner to the poster and tutorial at SciDAC 2008, this paper gives both a brief general description and some specific examples of new science enabled on the OSG. More information is available at the OSG web site: (http://www.opensciencegrid.org).

  15. Afrique Science: Revue Internationale des Sciences et Technologie ...

    African Journals Online (AJOL)

    Afrique Science: Revue Internationale des Sciences et Technologie: Journal Sponsorship. Journal Home > About the Journal > Afrique Science: Revue Internationale des Sciences et Technologie: Journal Sponsorship. Log in or Register to get access to full text downloads.

  16. Afrique Science: Revue Internationale des Sciences et Technologie ...

    African Journals Online (AJOL)

    Afrique Science: Revue Internationale des Sciences et Technologie: Site Map. Journal Home > About the Journal > Afrique Science: Revue Internationale des Sciences et Technologie: Site Map. Log in or Register to get access to full text downloads.

  17. Afrique Science: Revue Internationale des Sciences et Technologie ...

    African Journals Online (AJOL)

    Afrique Science: Revue Internationale des Sciences et Technologie: Contact. Journal Home > About the Journal > Afrique Science: Revue Internationale des Sciences et Technologie: Contact. Log in or Register to get access to full text downloads.

  18. Afrique Science: Revue Internationale des Sciences et Technologie ...

    African Journals Online (AJOL)

    Afrique Science: Revue Internationale des Sciences et Technologie: About this journal. Journal Home > Afrique Science: Revue Internationale des Sciences et Technologie: About this journal. Log in or Register to get access to full text downloads.

  19. Archives: Afrique Science: Revue Internationale des Sciences et ...

    African Journals Online (AJOL)

    Items 1 - 31 of 31 ... Archives: Afrique Science: Revue Internationale des Sciences et Technologie. Journal Home > Archives: Afrique Science: Revue Internationale des Sciences et Technologie. Log in or Register to get access to full text downloads.

  20. BES Science Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Biocca, Alan; Carlson, Rich; Chen, Jackie; Cotter, Steve; Tierney, Brian; Dattoria, Vince; Davenport, Jim; Gaenko, Alexander; Kent, Paul; Lamm, Monica; Miller, Stephen; Mundy, Chris; Ndousse, Thomas; Pederson, Mark; Perazzo, Amedeo; Popescu, Razvan; Rouson, Damian; Sekine, Yukiko; Sumpter, Bobby; Dart, Eli; Wang, Cai-Zhuang -Z; Whitelam, Steve; Zurawski, Jason

    2011-02-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivityfor the US Department of Energy Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of the Office ofScience programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years.

  1. Chemistry and Science Fiction

    Science.gov (United States)

    Stocker, Jack H.

    1998-11-01

    This lively collection looks at science as filtered through literature, film, and television. It discusses classic works in science fiction and provides an in-depth look at the chemistry depicted in popular culture, particularly in Start Trek , Star Wars , and Doctor Who . It includes an examination by Nebula Award winner Connie Willis of how science fiction authors use science, and reprints two tongue-in-cheek short stories by Isaac Asimov. The book also includes suggestions for using science fiction as an educational resource.

  2. Networks in Cognitive Science

    CERN Document Server

    Baronchelli, Andrea; Pastor-Satorras, Romualdo; Chater, Nick; Christiansen, Morten H

    2013-01-01

    Networks of interconnected nodes have long played a key role in cognitive science, from artificial neural networks to spreading activation models of semantic memory. Recently, however, a new Network Science has been developed, providing insights into the emergence of global, system-scale properties in contexts as diverse as the Internet, metabolic reactions or collaborations among scientists. Today, the inclusion of network theory into cognitive sciences, and the expansion of complex systems science, promises to significantly change the way in which the organization and dynamics of cognitive and behavioral processes are understood. In this paper, we review recent contributions of network theory at different levels and domains within the cognitive sciences.

  3. Media, risk and science

    CERN Document Server

    Allan, Stuart

    2002-01-01

    How is science represented by the media? Who defines what counts as a risk, threat or hazard, and why? In what ways do media images of science shape public perceptions? What can cultural and media studies tell us about current scientific controversies? "Media, Risk and Science" is an exciting exploration into an array of important issues, providing a much needed framework for understanding key debates on how the media represent science and risk. In a highly effective way, Stuart Allan weaves together insights from multiple strands of research across diverse disciplines. Among the themes he examines are: the role of science in science fiction, such as "Star Trek"; the problem of 'pseudo-science' in "The X-Files"; and how science is displayed in science museums. Science journalism receives particular attention, with the processes by which science is made 'newsworthy' unravelled for careful scrutiny. The book also includes individual chapters devoted to how the media portray environmental risks, HIV-AIDS, food s...

  4. JPRS Report, Science & Technology, USSR: Earth Sciences

    Science.gov (United States)

    1988-02-26

    copyright owner. SCIENCE & TECHNOLOGY USSR: EARTH SCIENCES CONTENTS OCEANOGRAPHY Determination of Mean Thermohaline Characteristics of the...MEAN THERMOHALINE CHARACTERISTICS OF THE OCEAN Moscow VESTNIK MOSKOVSKOGO UNIVERSITETA: SERIYA 5, GEOGRAFIYA in Russian No 3, May-Jun 87 (manuscript...motions in general are anisotropic). However, during a cruise of the "Akademik A. Vinogradov" it was discovered that during a calm the rotation of

  5. Science policy up close

    CERN Document Server

    Marburger, John H

    2015-01-01

    In a career that included tenures as president of Stony Brook University, director of Brookhaven National Laboratory, and science advisor to President George W. Bush, John Marburger (1941 2011) found himself on the front line of battles that pulled science ever deeper into the political arena. From nuclear power to global warming and stem cell research, science controversies, he discovered, are never just about science. Science Policy Up Close" presents Marburger s reflections on the challenges science administrators face in the twenty-first century. In each phase of public service Marburger came into contact with a new dimension of science policy. The Shoreham Commission exposed him to the problem of handling a volatile public controversy over nuclear power. The Superconducting Super Collider episode gave him insights into the collision between government requirements and scientists expectations and feelings of entitlement. The Directorship of Brookhaven taught him how to talk to the public about the risks ...

  6. A guided science

    DEFF Research Database (Denmark)

    Valsiner, Jaan

    That sciences are guided by explicit and implicit ties to their surrounding social world is not new. Jaan Valsiner fills in the wide background of scholarship on the history of science, the recent focus on social studies of sciences, and the cultural and cognitive analyses of knowledge making....... The theoretical scheme that he uses to explain the phenomena of social guidance of science comes from his thinking about processes of development in general—his theory of bounded indeterminacy—and on the relations of human beings with their culturally organized environments. Valsiner examines reasons for the slow...... and nonlinear progress of ideas in psychology as a science at the border of natural and social sciences. Why is that intellectual progress occurs in different countries at different times? Most responses are self-serving blinders for presenting science as a given rather than understanding it as a deeply human...

  7. WikiScience: Wikipedia for science and technology

    OpenAIRE

    Aibar Puentes, Eduard

    2015-01-01

    Peer-reviewed Presentació de la conferència "WikiScience: Wikipedia for science and technology". Presentación de la conferencia "WikiScience: Wikipedia for science and technology". Presentation of the conference "Science Wiki: Wikipedia for science and technology".

  8. The Double Helix: Why Science Needs Science Fiction.

    Science.gov (United States)

    Andreadis, Athena

    2003-01-01

    Discusses why science needs science fiction, commenting on the author's book about science that draws heavily on the "Star Trek" series. The best science, in spite of popular thinking, comes from leaps of intuition, and science fiction provides a creative spark that encourages participation in science. (SLD)

  9. Science Process Skills in Science Curricula Applied in Turkey

    Science.gov (United States)

    Yumusak, Güngör Keskinkiliç

    2016-01-01

    One of the most important objectives of the science curricula is to bring in science process skills. The science process skills are skills that lie under scientific thinking and decision-making. Thus it is important for a science curricula to be rationalized in such a way that it brings in science process skills. New science curricula were…

  10. Exoplanet Science in the National Science Olympiad

    Science.gov (United States)

    Komacek, Thaddeus D.; Young, Donna

    2015-11-01

    The National Science Olympiad is one of the United States' largest science competitions, reaching over 6,000 schools in 48 states. The Olympiad includes a wide variety of events, stretching a full range of potential future STEM careers, from biological sciences to engineering to earth and space sciences. The Astronomy event has been a mainstay at the high school level for well over a decade, and nominally focuses on aspects of stellar evolution. For the 2014-2015 competition season, the event focus was aligned to include exoplanet discovery and characterization along with star formation. Teams studied both the qualitative features of exoplanets and exoplanetary systems and the quantitative aspects behind their discovery and characterization, including basic calculations with the transit and radial velocity methods. Students were also expected to have a qualitative understanding of stellar evolution and understand the differences between classes of young stars including T Tauri and FU Orionis variables, and Herbig Ae/Be stars. Based on the successes of this event topic, we are continuing this event into the 2015-2016 academic year. The key modification is the selection of new exoplanetary systems for students to research. We welcome feedback from the community on how to improve the event and the related educational resources that are created for Science Olympiad students and coaches. We also encourage any interested community members to contact your regional or state Science Olympiad tournament directors and volunteer to organize competitions and supervise events locally.

  11. Science for Diplomacy, Diplomacy for Science

    Science.gov (United States)

    Colglazier, E. Wiliam

    2015-04-01

    I was a strong proponent of ``science diplomacy'' when I became Science and Technology Adviser to the Secretary of State in 2011. I thought I knew a lot about the subject after being engaged for four decades on international S&T policy issues and having had distinguished scientists as mentors who spent much of their time using science as a tool for building better relations between countries and working to make the world more peaceful, prosperous, and secure. I learned a lot from my three years inside the State Department, including great appreciation and respect for the real diplomats who work to defuse conflicts and avoid wars. But I also learned a lot about science diplomacy, both using science to advance diplomacy and diplomacy to advance science. My talk will focus on the five big things that I learned, and from that the one thing where I am focusing my energies to try to make a difference now that I am a private citizen again.

  12. Teaching Science Fiction by Women.

    Science.gov (United States)

    Donawerth, Jane

    1990-01-01

    Reviews the 200-year-old tradition of women science fiction authors. Discusses the benefits of teaching science fiction written by women. Describes 5 science fiction short stories and 5 science fiction novels suitable for high school students. (RS)

  13. Cameroon Journal of Agricultural Science

    African Journals Online (AJOL)

    Journal Camerounais des Sciences Agricoles The Cameroon Journal of Agricultural Science publishes new information on all aspects of agricultural science – agronomy, breeding, crop protection, economics, rural sociology, forestry and animal science, health and production ...

  14. Sciences sociales, sciences humaines et sciences de l'homme ...

    African Journals Online (AJOL)

    La science est constituée par l'ensemble des connaissances et des études de valeur universelle, caractérisées par une méthode et un objet déterminés, fondées sur des relations objectives et vérifiables. C'est bien dans ce même ordre d'idées que E. Schatzmann a pu soutenir la thèse selon laquelle la science est ...

  15. How to Motivate Science Teachers to Use Science Experiments

    Directory of Open Access Journals (Sweden)

    Josef Trna

    2012-10-01

    Full Text Available A science experiment is the core tool in science education. This study describes the science teachers' professional competence to implement science experiments in teaching/learning science. The main objective is the motivation of science teachers to use science experiments. The presented research tries to answer questions aimed at the science teachers' skills to use science experiments in teaching/learning science. The research discovered the following facts: science teachers do not include science experiments in teaching/learning in a suitable way; are not able to choose science experiments corresponding to the teaching phase; prefer teachers' demonstration of science experiments; are not able to improvise with the aids; use only a few experiments. The important research result is that an important motivational tool for science teachers is the creation of simple experiments. Examples of motivational simple experiments used into teachers' training for increasing their own creativity and motivation are presented.

  16. The World Science Festival

    Science.gov (United States)

    Pazmino, J.

    2012-06-01

    (Abstract only) New York City in the late 20th century rose to be a planetary capital for the sciences, not just astronomy. This growth was mainly in the academic sector but a parallel growth occurred in the public and home field. With the millennium crossing, scientists in New York agitated for a celebration of the City as a place for a thriving science culture. In 2008 they began World Science Festival. 2011 is the fourth running, on June 1-5, following the AAVSO/AAS meetings. World Science Festival was founded by Dr. Brian Greene, Columbia University, and is operated through the World Science Foundation. The Festival is "saturation science" all over Manhattan in a series of lectures, shows, exhibits, performances. It is staged in "science" venues like colleges and musea, but also in off-science spaces like theaters and galleries. It is a blend from hard science, with lectures like those by us astronomers, to science-themed works of art, dance, music. Events are fitted for the public, either for free or a modest fee. While almost all events are on Manhattan, effort has been made to geographically disperse them, even to the outer boroughs. The grand finale of World Science Festival is a street fair in Washington Square. Science centers in booths, tents, and pavilions highlight their work. In past years this fair drew 100,000 to 150,000 visitors. The entire Festival attracts about a quarter-million attendees. NYSkies is a proud participant at the Washington Square fair. It interprets the "Earth to the Universe" display, debuting during IYA-2009. Attendance at "Earth..." on just the day of the fair plausibly is half of all visitors in America. The presentation shows the scale and scope of World Science Festival, its relation to the City, and how our astronomers work with it.

  17. Science enrichment through informal science. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Katz, P.

    1996-07-01

    Hands On Science Outreach (HOSO) is a program of informal science education. Its mission is to bring to communities the option of out-of-school science explorations to small groups of children from the ages of 4-12. Such experiences encourage children to enjoy science without the fear of the consequences of failure that can occur in a formal school setting. It can start them on a life long pattern of participation, awareness and perhaps career interest, motivated by this kind of pleasurable learning. Since HOSO binds together adult training, materials and written guides, many of those not professionally employed in education, including parents, can and do become involved in {open_quotes}science for the fun of it.{close_quotes} The DOE grant to the HOSO program has funded the delivery of HOSO programming to five selected sites over the 1992-96 school years. It is the intention of both the DOE and HOSO to reach children who might otherwise not be able to afford the programming, with emphasis on underrepresented minorities. HOSO has developed fall, winter and spring theme-oriented informal science sessions on four age/grade levels. One hour classes take place once a week for eight weeks per session. At the original Washington, D.C. site, the program uses a mentoring model named STEPS (Successful Teaming for Educational Partnerships in Science) in partnership with the District of Columbia Schools, as well as HOSO and the DOE. That model continues to work in Washington, D.C. and has been replicated in parts of the Sacramento and Denver sites.

  18. Management of science policy, sociology of science policy and economics of science policy

    CERN Document Server

    Ruivo, Beatriz

    2017-01-01

    'Management of science policy, sociology of science policy and economics of science policy' is a theoretical essay on the scientific foundation of science policy (formulation, implementation, instruments and procedures). It can be also used as a textbook.

  19. Environmental Science: 49 Science Fair Projects. Science Fair Projects Series.

    Science.gov (United States)

    Bonnet, Robert L.; Keen, G. Daniel

    This book contains 49 science fair projects designed for 6th to 9th grade students. Projects are organized by the topics of soil, ecology (projects in habitat and life cycles), pests and controls (projects in weeds and insects), recycling (projects in resources and conservation), waste products (projects in decomposition), microscopic organisms,…

  20. Science: Servant or master?*

    Directory of Open Access Journals (Sweden)

    Elaine M. Botha

    1982-03-01

    Full Text Available The so-called omnipotence of modern science and technology rests on fundamental convictions and views regarding their basic nature. The mythical claims as to the demonic or magical role played by science in society are strengthened on the one hand by the scientists, and on the other hand they Find an easy access to a "lay" public. I he belief in the omnipotence of science leads to a belief in progress which, in the context of the modern science and technology which have been “freed of values”, is endowed with the Role of saviour in a world devoid of mysticism. For the practice of academic and intellectual stewardship in the allocation of a legitimate but limited role to science, one of the primary pre-requisites is the demythologizing of the over-extended expectations cherished of science as an idol of progress.

  1. Science, expertise, and democracy.

    Science.gov (United States)

    Weinberg, Justin; Elliott, Kevin C

    2012-06-01

    The combination of government's significant involvement in science, science's significant effects on the public, and public ignorance (of both politics and science) raise important challenges for reconciling scientific expertise with democratic governance. Nevertheless, there have recently been a variety of encouraging efforts to make scientific activity more responsive to social values and to develop citizens' capacity to engage in more effective democratic governance of science. This essay introduces a special issue of the Kennedy Institute of Ethics Journal, "Science, Expertise, and Democracy," consisting of five papers that developed from the inaugural Three Rivers Philosophy conference held at the University of South Carolina in April 2011. The pieces range from a general analysis of the in-principle compatibility of scientific expertise and democracy to much more concrete studies of the intersection between scientific practices and democratic values in areas such as weight-of-evidence analysis, climate science, and studies of locally undesirable land uses.

  2. 76 FR 38430 - Subcommittee on Forensic Science; Committee on Science; National Science and Technology Council

    Science.gov (United States)

    2011-06-30

    ... TECHNOLOGY POLICY Subcommittee on Forensic Science; Committee on Science; National Science and Technology... interoperability issues identified in the National Academy of Sciences 2009 report: ``Strengthening Forensic... ). SUMMARY: The Subcommittee on Forensic Science (SoFS) of the National Science and Technology Council's...

  3. Biomolecular Science (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-04-01

    A brief fact sheet about NREL Photobiology and Biomolecular Science. The research goal of NREL's Biomolecular Science is to enable cost-competitive advanced lignocellulosic biofuels production by understanding the science critical for overcoming biomass recalcitrance and developing new product and product intermediate pathways. NREL's Photobiology focuses on understanding the capture of solar energy in photosynthetic systems and its use in converting carbon dioxide and water directly into hydrogen and advanced biofuels.

  4. Science and commonsense

    OpenAIRE

    Ogborn, Jon

    2011-01-01

    This paper discusses the nature of scientific and commonsense knowledge, and their relationship to one another. The discussion is organised under four main themes: the nature of scientific knowledge and reasoning; the importance of science and of its role in the development of rationality; the nature of commonsense knowledge and reasoning; differences and similarities between science and commonsense. Finally, I discuss some implications for the teaching of science.

  5. COMPUTATIONAL SCIENCE CENTER

    Energy Technology Data Exchange (ETDEWEB)

    DAVENPORT,J.

    2004-11-01

    The Brookhaven Computational Science Center brings together researchers in biology, chemistry, physics, and medicine with applied mathematicians and computer scientists to exploit the remarkable opportunities for scientific discovery which have been enabled by modern computers. These opportunities are especially great in computational biology and nanoscience, but extend throughout science and technology and include for example, nuclear and high energy physics, astrophysics, materials and chemical science, sustainable energy, environment, and homeland security.

  6. Data-intensive science

    CERN Document Server

    Critchlow, Terence

    2013-01-01

    Data-intensive science has the potential to transform scientific research and quickly translate scientific progress into complete solutions, policies, and economic success. But this collaborative science is still lacking the effective access and exchange of knowledge among scientists, researchers, and policy makers across a range of disciplines. Bringing together leaders from multiple scientific disciplines, Data-Intensive Science shows how a comprehensive integration of various techniques and technological advances can effectively harness the vast amount of data being generated and significan

  7. Towards Data Science

    OpenAIRE

    Yangyong Zhu; Yun Xiong

    2015-01-01

    Currently, a huge amount of data is being rapidly generated in cyberspace. Datanature (all data in cyberspace) is forming due to a data explosion. Exploring the patterns and rules in datanature is necessary but difficult. A new discipline called Data Science is coming. It provides a type of novel research method (a data-intensive method) for natural and social sciences and goes beyond computer science in researching data. This paper presents the challenges presented by data and discusses what...

  8. Data science from scratch

    CERN Document Server

    Grus, Joel

    2015-01-01

    This is a first-principles-based, practical introduction to the fundamentals of data science aimed at the mathematically-comfortable reader with some programming skills. The book covers: * The important parts of Python to know * The important parts of Math / Probability / Statistics to know * The basics of data science * How commonly-used data science techniques work (learning by implementing them) * What is Map-Reduce and how to do it in Python * Other applications such as NLP, Network Analysis, and more

  9. Animal science in the context of food consumer science:

    OpenAIRE

    Pohar, Jurij

    2012-01-01

    The food consumer science as the science with the ambition to overcome the difference between food science and consumer science is presented. The major stakeholders involved are listed and the role of animal science and animal scientists within the framework of food consumer science is discoursed. The importance of animal scientists to understand the complexity of food consumer science knowledge system and need for them to broaden the scope of interest beyond the traditional area of expertise...

  10. BER Science Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Alapaty, Kiran; Allen, Ben; Bell, Greg; Benton, David; Brettin, Tom; Canon, Shane; Dart, Eli; Cotter, Steve; Crivelli, Silvia; Carlson, Rich; Dattoria, Vince; Desai, Narayan; Egan, Richard; Tierney, Brian; Goodwin, Ken; Gregurick, Susan; Hicks, Susan; Johnston, Bill; de Jong, Bert; Kleese van Dam, Kerstin; Livny, Miron; Markowitz, Victor; McGraw, Jim; McCord, Raymond; Oehmen, Chris; Regimbal, Kevin; Shipman, Galen; Strand, Gary; Flick, Jeff; Turnbull, Susan; Williams, Dean; Zurawski, Jason

    2010-11-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the US Department of Energy Office of Science, the single largest supporter of basic research in the physical sciences in the United States. In support of the Office of Science programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years. In April 2010 ESnet and the Office of Biological and Environmental Research, of the DOE Office of Science, organized a workshop to characterize the networking requirements of the science programs funded by BER. The requirements identified at the workshop are summarized and described in more detail in the case studies and the Findings section. A number of common themes emerged from the case studies and workshop discussions. One is that BER science, like many other disciplines, is becoming more and more distributed and collaborative in nature. Another common theme is that data set sizes are exploding. Climate Science in particular is on the verge of needing to manage exabytes of data, and Genomics is on the verge of a huge paradigm shift in the number of sites with sequencers and the amount of sequencer data being generated.

  11. Practical data science cookbook

    CERN Document Server

    Ojeda, Tony; Bengfort, Benjamin; Dasgupta, Abhijit

    2014-01-01

    If you are an aspiring data scientist who wants to learn data science and numerical programming concepts through hands-on, real-world project examples, this is the book for you. Whether you are brand new to data science or you are a seasoned expert, you will benefit from learning about the structure of data science projects, the steps in the data science pipeline, and the programming examples presented in this book. Since the book is formatted to walk you through the projects with examples and explanations along the way, no prior programming experience is required.

  12. Great Lakes Science Center

    Data.gov (United States)

    Federal Laboratory Consortium — Since 1927, Great Lakes Science Center (GLSC) research has provided critical information for the sound management of Great Lakes fish populations and other important...

  13. Assessment in Science Education

    Science.gov (United States)

    Rustaman, N. Y.

    2017-09-01

    An analyses study focusing on scientific reasoning literacy was conducted to strengthen the stressing on assessment in science by combining the important of the nature of science and assessment as references, higher order thinking and scientific skills in assessing science learning as well. Having background in developing science process skills test items, inquiry in its many form, scientific and STEM literacy, it is believed that inquiry based learning should first be implemented among science educators and science learners before STEM education can successfully be developed among science teachers, prospective teachers, and students at all levels. After studying thoroughly a number of science researchers through their works, a model of scientific reasoning was proposed, and also simple rubrics and some examples of the test items were introduced in this article. As it is only the beginning, further studies will still be needed in the future with the involvement of prospective science teachers who have interests in assessment, either on authentic assessment or in test items development. In balance usage of alternative assessment rubrics, as well as valid and reliable test items (standard) will be needed in accelerating STEM education in Indonesia.

  14. Handbook of information science

    CERN Document Server

    Stock, Wolfgang G

    2013-01-01

    Dealing with information is one of the vital skills in thetwenty-first century. It takes a fair degree of information savvy to create, represent and supply information as well as to search for and retrieve relevant knowledge. This Handbook is a basic work of information science, providing a comprehensive overview of the current state of information retrieval and knowledge representation. It addresses readers from all professions and scientific disciplines, but particularly scholars, practitioners and students of Information Science, Library Science, Computer Science, Information Management, an

  15. Physical Sciences Laboratory (PSL)

    Data.gov (United States)

    Federal Laboratory Consortium — PNNL's Physical Sciences Laboratory (PSL) houses 22 research laboratories for conducting a wide-range of research including catalyst formulation, chemical analysis,...

  16. WFIRST Project Science Activities

    Science.gov (United States)

    Gehrels, Neil

    2012-01-01

    The WFIRST Project is a joint effort between GSFC and JPL. The project scientists and engineers are working with the community Science Definition Team to define the requirements and initial design of the mission. The objective is to design an observatory that meets the WFIRST science goals of the Astr02010 Decadal Survey for minimum cost. This talk will be a report of recent project activities including requirements flowdown, detector array development, science simulations, mission costing and science outreach. Details of the interim mission design relevant to scientific capabilities will be presented.

  17. Data Science Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Data Science is emerging as a critical area of research and technology to advance scientific discovery, knowledge and decision making through systematic...

  18. Data science for dummies

    CERN Document Server

    Pierson, Lillian

    2015-01-01

    Discover how data science can help you gain in-depth insight into your business - the easy way! Jobs in data science abound, but few people have the data science skills needed to fill these increasingly important roles in organizations. Data Science For Dummies is the perfect starting point for IT professionals and students interested in making sense of their organization's massive data sets and applying their findings to real-world business scenarios. From uncovering rich data sources to managing large amounts of data within hardware and software limitations, ensuring consistency in report

  19. School of Political Science

    Directory of Open Access Journals (Sweden)

    A. D. Voskresensky

    2014-01-01

    Full Text Available Out of all the departments of political sciences in Russia - the Department at MGIMO-University is probably the oldest one. In fact it is very young. While MGIMO-University is celebrating its 70th anniversary the Department of Political Sciences turns 15. Despite the fact that political analyst is a relatively new profession in Russia, it acquired a legal standing only in the 1990s, the political science school at MGIMO-University is almost as old as the university itself. Unlike many other universities, focused on the training teachers of political science or campaign managers MGIMO-University has developed its own unique political science school of "full cycle", where students grow into political sciences from a zero level up to the highest qualifications as teachers and researchers, and campaign managers, consultants and practitioners. The uniqueness of the school of political science at MGIMO-University allows its institutional incarnation -the Department of Political Science - to offer prospective studentsa training in a wide range of popular specialties and specializations, while ensuring a deep theoretical and practical basis of the training. Studying at MGIMO-University traditionally includes enhanced linguistic component (at least two foreign languages. For students of international relations and political science learning foreign languages is particularly important.It allows not only to communicate, but also to produce expertise and knowledge in foreign languages.

  20. THE NATURE OF SCIENCE

    Directory of Open Access Journals (Sweden)

    R. Trigg

    2014-11-01

    Full Text Available The study defines social science and its specific in contrast with history, psychology and physical sciences. Also it emphasizes the importance of the idea of a 'value-free' science for the social sciences is clear. Social scientists want to be seen to establish 'facts' about society in the same way that they think that a physicist or a chemist uncovers 'facts'. Using the theories of Hempel, Quine, Feyerabend and Kuhn, it addresses a series of questions concening scientific theories, their roles for the scientific explanation and the scientific progress.

  1. Theoretical computer science and the natural sciences

    Science.gov (United States)

    Marchal, Bruno

    2005-12-01

    I present some fundamental theorems in computer science and illustrate their relevance in Biology and Physics. I do not assume prerequisites in mathematics or computer science beyond the set N of natural numbers, functions from N to N, the use of some notational conveniences to describe functions, and at some point, a minimal amount of linear algebra and logic. I start with Cantor's transcendental proof by diagonalization of the non enumerability of the collection of functions from natural numbers to the natural numbers. I explain why this proof is not entirely convincing and show how, by restricting the notion of function in terms of discrete well defined processes, we are led to the non algorithmic enumerability of the computable functions, but also-through Church's thesis-to the algorithmic enumerability of partial computable functions. Such a notion of function constitutes, with respect to our purpose, a crucial generalization of that concept. This will make easy to justify deep and astonishing (counter-intuitive) incompleteness results about computers and similar machines. The modified Cantor diagonalization will provide a theory of concrete self-reference and I illustrate it by pointing toward an elementary theory of self-reproduction-in the Amoeba's way-and cellular self-regeneration-in the flatworm Planaria's way. To make it easier, I introduce a very simple and powerful formal system known as the Schoenfinkel-Curry combinators. I will use the combinators to illustrate in a more concrete way the notion introduced above. The combinators, thanks to their low-level fine grained design, will also make it possible to make a rough but hopefully illuminating description of the main lessons gained by the careful observation of nature, and to describe some new relations, which should exist between computer science, the science of life and the science of inert matter, once some philosophical, if not theological, hypotheses are made in the cognitive sciences. In the

  2. Energy, information science, and systems science

    Energy Technology Data Exchange (ETDEWEB)

    Wallace, Terry C [Los Alamos National Laboratory; Mercer - Smith, Janet A [Los Alamos National Laboratory

    2011-02-01

    This presentation will discuss global trends in population, energy consumption, temperature changes, carbon dioxide emissions, and energy security programs at Los Alamos National Laboratory. LANL's capabilities support vital national security missions and plans for the future. LANL science supports the energy security focus areas of impacts of Energy Demand Growth, Sustainable Nuclear Energy, and Concepts and Materials for Clean Energy. The innovation pipeline at LANL spans discovery research through technology maturation and deployment. The Lab's climate science capabilities address major issues. Examples of modeling and simulation for the Coupled Ocean and Sea Ice Model (COSIM) and interactions of turbine wind blades and turbulence will be given.

  3. [What is sustainability science?].

    Science.gov (United States)

    Wu, Jian-Guo; Guo, Xiao-Chuan; Yang, Jie; Qian, Gui-Xia; Niu, Jian-Ming; Liang, Cun-Zhu; Zhang, Qing; Li, Ang

    2014-01-01

    Sustainability is the theme of our time and also the grandest challenge to humanity. Since the 1970s, the term, sustainable development, has frequently appeared in the scientific literature, governmental documents, media promotions for public goods, and commercial advertisements. However, the science that provides the theoretical foundation and practical guidance for sustainable development--sustainability science--only began to emerge in the beginning of the 21st century. Nevertheless, the field has rapidly developed in depth and expanded in scope during the past decade, with its core concepts and research methods coalescing. China, as the most populous country in the world and home to the philosophical root of sustainability science-the unity of man and nature, is obligated to take upon the challenge of our time, to facilitate global sustainability while pursuing the Chinese Dream, and to play a leading role in the development of sustainability science. Toward this grandiose goal, this paper presents the first Chinese introduction to sustainability science, which discusses its basic concepts, research questions, and future directions. Sustainability science is the study of the dynamic relationship between humans and the environment, particularly focusing on the vulnerability, robustness, resilience, and stability of the coupled human-environment system. It is a transdisciplinary science that integrates natural sciences with humanities and social sciences. It hinges on the environment-economy-society nexus, and merges basic and applied research. The key components of sustainability often change with time, place, and culture, and thus sustainability science needs to emphasize multi-scale studies in space and time, with emphasis on landscapes and regions over a horizon of 50 to 100 years. It needs to focus on the relationship between ecosystem services and human well-being, as influenced by biodiversity and ecosystem processes as well as climate change, land use

  4. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. S K Kataria. Articles written in Pramana – Journal of Physics. Volume 63 Issue 2 August 2004 pp 459-463 Contributed Papers : Neutron instrumentation. Instrumentation for PSD-based neutron diffractometers at Dhruva reactor · S S Pande S P Borkar S Prafulla V D Srivastava ...

  5. Home Culture, Science, School and Science Learning: Is Reconciliation Possible?

    Science.gov (United States)

    Tan, Aik-Ling

    2011-01-01

    In response to Meyer and Crawford's article on how nature of science and authentic science inquiry strategies can be used to support the learning of science for underrepresented students, I explore the possibly of reconciliation between the cultures of school, science, school science as well as home. Such reconciliation is only possible when…

  6. Adapting Practices of Science Journalism to Foster Science Literacy

    Science.gov (United States)

    Polman, Joseph L.; Newman, Alan; Saul, Ellen Wendy; Farrar, Cathy

    2014-01-01

    In this paper, the authors describe how the practices of expert science journalists enable them to act as "competent outsiders" to science. We assert that selected science journalism practices can be used to design reform-based science instruction; these practices not only foster science literacy that is useful in daily life, but also…

  7. Other Women in Science Groups | Women in Science | Initiatives ...

    Indian Academy of Sciences (India)

    Other Women in Science Groups. Here is the information on various national and international groups/organizations working towards empowering women participation in science. 1. DST Task Force on Women in Science. The Department of Science & Technology has set up a National Task Force on Women in Science to ...

  8. Science communication for uncertian science and innovation

    NARCIS (Netherlands)

    van der Sanden, M.C.A.; Flipse, S.M.

    2016-01-01

    Differences in viewpoints between science and society, like in for example the HPV-vaccination debate, should be considered from a socio-technical system perspective, and not solely from a boundary perspective between the lay public, medical doctors and scientists. Recent developments in the

  9. JPRS Report, Science & Technology, USSR: Materials Science.

    Science.gov (United States)

    1988-04-04

    Producing Kovar-To-Glass Seals by Heating With Light From Xenon^Arc Lamps CM. 1, Oparin , V. B. Redchits; SVAROCHNOYE PROIZVODSTVO, No 11, Nov 87) 28...10-11 iArticle by M, I, Oparin , candidate of technical sciences, and V, B. Redchits, engineer] [Abstract] Hermetic Kovar-to-glass seals were

  10. Learning Science: Some Insights from Cognitive Science.

    Science.gov (United States)

    Matthews, P. S. C.

    2000-01-01

    Theories of teaching and learning on human cognition depend on domain-free, general purpose processing by the brain. Cognition is modular in nature and often domain-specific. Children's ideas in science are often triggered rather than learned. Triggered conceptual structures are not necessarily expressible in language and may not be susceptible to…

  11. JPRS Report Science & Technology USSR: Life Sciences.

    Science.gov (United States)

    1988-12-15

    secretion of gonadotropin and thyrotropin. The distribution of opioid peptides in the central nervous system (CNS) indicates that enkephalins are...Animals, USSR Academy of Sciences, Mos- cow ] [Abstract] Therapeutic trials were conducted in male and female C57B1 mice (18-25 g) to further assess the

  12. Science Fair Projects. LC Science Tracer Bullet.

    Science.gov (United States)

    Howland, Joyce, Comp.

    The sources listed in this document are selected to provide guidance to students, parents, and teachers throughout the process of planning, developing, implementing, and competing in science fair activities. While sources range in suitability from elementary to high school levels, the emphasis is on materials for grades 9-12. This guide updates LC…

  13. Computer Science Professionals and Greek Library Science

    Science.gov (United States)

    Dendrinos, Markos N.

    2008-01-01

    This paper attempts to present the current state of computer science penetration into librarianship in terms of both workplace and education issues. The shift from material libraries into digital libraries is mirrored in the corresponding shift from librarians into information scientists. New library data and metadata, as well as new automated…

  14. Differentiating Science Instruction: Secondary science teachers' practices

    Science.gov (United States)

    Maeng, Jennifer L.; Bell, Randy L.

    2015-09-01

    This descriptive study investigated the implementation practices of secondary science teachers who differentiate instruction. Participants included seven high school science teachers purposefully selected from four different schools located in a mid-Atlantic state. Purposeful selection ensured participants included differentiated instruction (DI) in their lesson implementation. Data included semi-structured interviews and field notes from a minimum of four classroom observations, selected to capture the variety of differentiation strategies employed. These data were analyzed using a constant-comparative approach. Each classroom observation was scored using the validated Differentiated Instruction Implementation Matrix-Modified, which captured both the extent to which critical indicators of DI were present in teachers' instruction and the performance levels at which they engaged in these components of DI. Results indicated participants implemented a variety of differentiation strategies in their classrooms with varying proficiency. Evidence suggested all participants used instructional modifications that required little advance preparation to accommodate differences in students' interests and learning profile. Four of the seven participants implemented more complex instructional strategies that required substantial advance preparation by the teacher. Most significantly, this study provides practical strategies for in-service science teachers beginning to differentiate instruction and recommendations for professional development and preservice science teacher education.

  15. Science Denial and the Science Classroom

    Science.gov (United States)

    Liu, Dennis W. C.

    2012-01-01

    Biology teachers are accustomed to engaging individuals who do not accept biological evolution. Denial of evolution ranges from ignorance of the evidence to outright denial or distortion of data. The list of science denial topics has grown alarmingly over the years to include: HIV as the cause of AIDS, exaggeration of the health and environmental…

  16. History of Science and Science Museums

    Science.gov (United States)

    Faria, Cláudia; Guilherme, Elsa; Gaspar, Raquel; Boaventura, Diana

    2015-01-01

    The activities presented in this paper, which are addressed to elementary school, are focused on the pioneering work of the Portuguese King Carlos I in oceanography and involve the exploration of the exhibits belonging to two different science museums, the Aquarium Vasco da Gama and the Maritime Museum. Students were asked to study fish…

  17. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 15; Issue 10. Dawn of Science - The Healing Art. T Padmanabhan. Series Article Volume 15 Issue 10 October 2010 pp 870-874. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/015/10/0870-0874. Keywords.

  18. Ife Journal of Science

    African Journals Online (AJOL)

    Ife Journal of Science (IJS) aims to publish articles resulting from original research in the broad areas of chemical, biological, mathematical and physical sciences. ... Freshwater diatoms diversity of national parks in Nigeria I: Okomu national park, South-South, Nigeria · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  19. Controversy in science

    Indian Academy of Sciences (India)

    M G Narasimhan1. Science and Society Unit, National Institute of Advanced Studies, Indian Institute of Science Campus, Bangalore 560 012, India. Journal of Biosciences. Current Issue : Vol. 42, Issue 4 · Current Issue Volume 42 | Issue 4. December 2017. Home · Volumes & Issues · Special Issues · Forthcoming Articles ...

  20. Sci-Fi Science.

    Science.gov (United States)

    Nauman, Ann K.; Shaw, Edward L.

    1994-01-01

    In today's rapidly changing world, science fiction can provide a bridge and a stimulus to the imagination of children. Provides an annotated bibliography of 25 science fiction titles for grades 1-3, 4-6, and 7-9. Suggests classroom applications including individual assignments, group discussion topics, and other activities. (LZ)

  1. The Image of Science

    NARCIS (Netherlands)

    J.W. Becker; P.M. van Rooijen

    2001-01-01

    Original title: Het beeld van de wetenschap. Whether they realise it or not, every Dutch citizen is affected every day by the results of science and technology. Yet research on the public perception of science and technology is scarce. The year 2000 marked the fiftieth anniversary of the of

  2. Science Teachers and Liability.

    Science.gov (United States)

    Nigro, Kirk A.

    Civil lawsuits brought for injuries to students are a source of growing concern for teachers, and especially for science teachers. This paper outlines some basic principles by which science teachers may protect themselves from lawsuits, before and during the time that students are engaged in experiments or lab work. Courts in this country have…

  3. Safety and Science Teaching.

    Science.gov (United States)

    Virginia State Dept. of Education, Richmond. Div. of Sciences and Elementary Administration.

    This 10-chapter handbook (designed for science teachers and school administrators) describes known hazards associated with science teaching and provides information to develop a framework for local safety programs specifically designed to avoid or neutralize the effects of such hazards. Major areas addressed in the chapters include: (1) the nature…

  4. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 2. Dawn of Science - The Conquest of the Seas. T Padmanabhan. Series Article Volume 16 Issue 2 February 2011 pp 110-115. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/02/0110-0115 ...

  5. NASA science communications strategy

    Science.gov (United States)

    1995-01-01

    In 1994, the Clinton Administration issued a report, 'Science in the National Interest', which identified new national science goals. Two of the five goals are related to science communications: produce the finest scientists and engineers for the 21st century, and raise scientific and technological literacy of all Americans. In addition to the guidance and goals set forth by the Administration, NASA has been mandated by Congress under the 1958 Space Act to 'provide for the widest practicable and appropriate dissemination concerning its activities and the results thereof'. In addition to addressing eight Goals and Plans which resulted from a January 1994 meeting between NASA and members of the broader scientific, education, and communications community on the Public Communication of NASA's Science, the Science Communications Working Group (SCWG) took a comprehensive look at the way the Agency communicates its science to ensure that any changes the Agency made were long-term improvements. The SCWG developed a Science Communications Strategy for NASA and a plan to implement the Strategy. This report outlines a strategy from which effective science communications programs can be developed and implemented across the agency. Guiding principles and strategic themes for the strategy are provided, with numerous recommendations for improvement discussed within the respective themes of leadership, coordination, integration, participation, leveraging, and evaluation.

  6. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 5. Dawn of Science - The Quest for Power. T Padmanabhan. Series Article Volume 17 Issue 5 May 2012 pp 436-440. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/017/05/0436-0440. Keywords.

  7. Democratizing Computer Science

    Science.gov (United States)

    Margolis, Jane; Goode, Joanna; Ryoo, Jean J.

    2015-01-01

    Computer science programs are too often identified with a narrow stratum of the student population, often white or Asian boys who have access to computers at home. But because computers play such a huge role in our world today, all students can benefit from the study of computer science and the opportunity to build skills related to computing. The…

  8. Dawn of Science

    Indian Academy of Sciences (India)

    Questions of this nature were the ones which prompted Darwin to his remarkable discovery. Suggested Reading. [1]. Isaac Asimov, Asimov's Biographical Encyclopedia of Science and Tech- nology, Doubleday, 1982. [2]. R Spangenburg and D K Moser, The Birth of Science – Volume I, Viva. Books Pvt. Ltd., 2006. Figure 8.

  9. Dawn of Science

    Indian Academy of Sciences (India)

    Suggested Reading. [1]. Arthur Koestler, Sleep walkers, Penguin, 1959. [2]. Isaac Asimov, Asimov's Biographical Encyclopedia of Science and. Technology, Doubleday. 1982. [3]. R Spangenburg and D K Moser, The Birth of Science Volume I: Ancient. Times to 1699, Viva Books Pvt. Ltd, 2006. Address for Correspondence.

  10. Is Psychology a Science?

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 11. Is Psychology a Science ? Kamala V Mukunda. General Article Volume 2 Issue 11 November 1997 pp 59-66. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/002/11/0059-0066. Author Affiliations.

  11. Signing in Science

    Science.gov (United States)

    Ashby, Rachael

    2013-01-01

    This article describes British Sign Language (BSL) as a viable option for teaching science. BSL is used by a vast number of people in Britain but is seldom taught in schools or included informally alongside lessons. With its new addition of a large scientific glossary, invented to modernise the way science is taught to deaf children, BSL breaks…

  12. Women in Science

    Indian Academy of Sciences (India)

    CICINCES. C.V. Raman Avenue, P.B. No. 8005. Sadashivanagar P.O., Bangalore-560 080, INDIA. Tel : 91-80-23612546, 23614592, 23611034 Pºº P Haº. is j Women in Science. E-mail: womenscióDias.ernet.in d - An Indian Academy of Sciences Initiative. SANATANADHARMA college. - Alappuzha. § §: - - 2. : & . - - X- …

  13. Carnap on unified science

    Czech Academy of Sciences Publication Activity Database

    Klev, Ansten

    -, č. 59 (2016), s. 53-67 ISSN 0039-3681 Institutional support: RVO:67985955 Keywords : Rudolf Carnap * Unity of Science * Logical Empiricism Subject RIV: AA - Philosophy ; Religion Impact factor: 0.723, year: 2016 http://www.sciencedirect.com/science/article/pii/S0039368116300206

  14. Science World Journal

    African Journals Online (AJOL)

    The SWJ is a peer review on-line international journal of broad appeal, aimed at fast publication of cutting edge research across the sciences. The Journal publishes multidisciplinary articles reporting on original research in the natural and physical sciences and their applications. The journal also promotes the application of ...

  15. Agro-Science

    African Journals Online (AJOL)

    Agro-Science, the journal of the Faculty of Agriculture of the University of Nigeria, was borne out of the need for a forum and technical mouthpiece for the communication and extension of scientific and agricultural research in Africa Agro-Science is an international journal of high technical/intellectual quality, published three ...

  16. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 9. Dawn of Science - The Invisible Weight. T Padmanabhan. Series Article Volume 16 Issue 9 September 2011 pp 854-859. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/09/0854-0859 ...

  17. Beyond Big Science

    CERN Multimedia

    Boyle, Alan

    2007-01-01

    "Billion-dollar science projects end up being about much more than the science, whether we're talking about particle physics, or fusion research, or the international space station, or missions to the moon and beyond, or the next-generation radio telescope." (3 pages)

  18. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 15; Issue 9. Dawn of Science - Archimedes. T Padmanabhan. Series Article Volume 15 Issue 9 September 2010 pp 774-778. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/015/09/0774-0778. Keywords.

  19. What is Science?

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-07-01

    Helen Quinn is a theoretical particle physicist at SLAC. Throughout her career, she has been passionately involved in science education and public understanding of science. In talking about science, whether to the public or to students, we scientists often assume that they share with us a common idea of science. In my experience that is often not the case. To oversimplify, scientists think of science both as a process for discovering properties of nature, and as the resulting body of knowledge, whereas most people seem to think of science, or perhaps scientists, as an authority that provides some information--just one more story among the many that they use to help make sense of their world. Can we close that gap in understanding? Middle school teachers typically spend a day or so teaching something called the scientific method, but the process by which scientific ideas are developed and tested is messier and much more interesting than that typical capsule description. Some remarkable features of the process are seldom stressed in teaching science, nor are they addressed in explaining any one piece of science to the public. My goal in this column is to provide some ideas for closing that gap in understanding, and to encourage scientists and teachers to communicate about the process as they discuss scientific work.

  20. Workshops on Writing Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 22; Issue 7. Workshops on Writing Science. Information and Announcements Volume 22 Issue 7 July 2017 pp 718-718. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/022/07/0718-0718. Abstract ...

  1. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 8. Dawn of Science - The Affairs of the Heart. T Padmanabhan. Series Article Volume 16 Issue 8 August 2011 pp 770-775. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/08/0770-0775 ...

  2. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 1. Dawn of Science - Measuring the Heavens. T Padmanabhan. Series Article Volume 17 Issue 1 January 2012 pp 6-10. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/017/01/0006-0010 ...

  3. Making Science Work.

    Science.gov (United States)

    Thomas, Lewis

    1981-01-01

    Presents a viewpoint concerning the impact of recent scientific advances on society. Discusses biological discoveries, space exploration, computer technology, development of new astronomical theories, the behavioral sciences, and basic research. Challenges to keeping science current with technological advancement are also discussed. (DS)

  4. Building Collections: Science Fiction

    Science.gov (United States)

    Krapp, JoAnn Vergona

    2005-01-01

    Fantasy and science fiction are two genres that are products of imagination. Both present alternate worlds governed by their own laws and values, but it is the plausibility of events in each world that sets the two apart. In fantasy, events happen by magic or inexplicable means. In science fiction, events could happen based on advanced…

  5. Archives: Zimbabwe Science News

    African Journals Online (AJOL)

    Items 1 - 10 of 10 ... Archives: Zimbabwe Science News. Journal Home > Archives: Zimbabwe Science News. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 10 of 10 Items. 2002 ...

  6. Encyclopedia of Rose Science

    NARCIS (Netherlands)

    Roberts, A.; Debener, T.; Gudin, S.; Byrne, D.B.; Cairns, T.; Vries, de D.P.; Dubois, L.A.M.; Forkmann, G.; Fruchter, M.; Helsper, J.P.F.G.; Horst, R.K.; Jay, M.; Kwakkenbosch, T.A.M.; Pemberton, B.; Put, H.M.C.; Rajapakse, S.; Reid, M.; Schum, A.; Shorthouse, J.D.; Ueda, Y.; Vainstein, A.; Pol, van de P.A.; Zieslin, N.

    2003-01-01

    The Encyclopedia of Rose Science brings together a wealth of information on the rose, long treasured for its captivating perfumes and splendid colors. Now, more than ever, science plays a central place in the production of this flower at the center of one of the world's biggest floricultural

  7. Learning English, Learning Science

    Science.gov (United States)

    Nelson, Virginia

    2010-01-01

    Using science notebooks effectively in the classroom can encourage students who are learning English to keep up and keep interested. English language proficiency might head the list of content areas that schools can teach properly and effectively through science. Amaral, Garrison, and Klentschy (2002) reported that a successful inquiry-based…

  8. Rudiments of materials science

    CERN Document Server

    Pillai, SO

    2007-01-01

    Writing a comprehensive book on Materials Science for the benefit of undergraduate courses in Science and Engineering was a day dream of the first author, Dr. S.O. Pillai for a long period. However, the dream became true after a lapse of couple of years. Lucid and logical exposition of the subject matter is the special feature of this book.

  9. NATO and Science.

    Science.gov (United States)

    Durand, Henry

    1988-01-01

    Outlines the Third Dimension of NATO. Presses for increased efforts to overcome the disparity in the rate of scientific development among the countries of the alliance. Discusses scientific nobility, the rise of European science, science for stability, environmental protection, and the changed scientific climate. (CW)

  10. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 11. Dawn of Science - The Questions of Life. T Padmanabhan. Series Article Volume 16 Issue 11 ... Keywords. Francesco Redi; Antony Van Leeuwenhoek; Marcello Malphigi; Lazzaro Spallanzani; John Ray; Carl Linnaeus; microscopes.

  11. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 7. Dawn of Science-The Galilean World. T Padmanabhan. Series Article Volume 16 Issue 7 July 2011 pp 663-669. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/07/0663-0669. Keywords.

  12. Archives: Sciences & Nature

    African Journals Online (AJOL)

    Items 1 - 9 of 9 ... Archives: Sciences & Nature. Journal Home > Archives: Sciences & Nature. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 9 of 9 Items. 2011. Vol 8, No 1-2 ...

  13. Making 'Sense' of Science.

    Science.gov (United States)

    Gosse, Bonnie

    1996-01-01

    Addresses the need for a good science program to teach students to integrate both the analytical and the creative pathways of inquiry. Also compares the specific functions of the brain's right (creative) and left (analytical) hemispheres as related to science. Suggests how to design a creative sense-gathering activity, and offers several sample…

  14. Acid Rain: Science Projects.

    Science.gov (United States)

    Hessler, Edward W.; Stubbs, Harriett S.

    Too often science seems to be a matter of studying from books and responding to questions raised by teachers about the information either in the classroom or on examinations. Such a view of science misses its importance as a way of thinking, doing, and preparing for citizenship roles. The problems and activities included in this volume are…

  15. K-6 Science Curriculum.

    Science.gov (United States)

    Blueford, J. R.; And Others

    A unified science approach is incorporated in this K-6 curriculum mode. The program is organized into six major cycles. These include: (1) science, math, and technology cycle; (2) universe cycle; (3) life cycle; (4) water cycle; (5) plate tectonics cycle; and (6) rock cycle. An overview is provided of each cycle's major concepts. The topic…

  16. Spitting for Science

    DEFF Research Database (Denmark)

    Athanasiadis, Georgios; Jorgensen, Frank G.; Cheng, Jade Y.

    2016-01-01

    Scientific outreach delivers science to the people. But it can also deliver people to the science. In this work, we report our experience from a large-scale public engagement project promoting genomic literacy among Danish high school students with the additional benefit of collecting data...

  17. Fermentation. Third World Science.

    Science.gov (United States)

    Jones, Natalie; Hughes, Wyn

    This unit, developed by the Third World Science Project, is designed to add a multicultural element to existing science syllabi (for students aged 11-16) in the United Kingdom. The project seeks to develop an appreciation of the: boundless fascination of the natural world; knowledge, skills, and expertise possessed by men/women everywhere;…

  18. Nationaal plan open science

    NARCIS (Netherlands)

    van Wezenbeek, W.J.S.M.; Touwen, H.J.J.; Versteeg, A.M.C.; van Wesenbeeck, Astrid

    2017-01-01

    This National Plan Open Science sets out what the Dutch parties involved in creating this Plan are already doing and what they plan to do to grasp the opportunities and at the same time make science even more accessible to others. A major boost is required if these initiatives are to be coordinated

  19. Archives: Science World Journal

    African Journals Online (AJOL)

    Items 1 - 39 of 39 ... Archives: Science World Journal. Journal Home > Archives: Science World Journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 39 of 39 Items. 2017 ...

  20. Rethinking the Science Fair

    Science.gov (United States)

    Craven, John; Hogan, Tracy

    2008-01-01

    Spring is the season when thousands of creased cardboard pests can be found lodged under the armpits of students and teachers as they observe the educational rite of spring known as the school science fair. A recent visit to a local school's gymnasium to witness one of these events reminded the authors of why they so dislike science fairs. In this…

  1. Games for Psychological Science.

    Science.gov (United States)

    Howes, Andrew

    2017-04-01

    How does the cognitive system, as a whole, act to generate behaviour? A crucial requirement for science aimed at answering this question is that any empirical paradigm is developed hand in hand with robust theoretical models that explain the emergence of behavioural strategies. Complex games have the potential to be one such paradigm. Copyright © 2017 Cognitive Science Society, Inc.

  2. Weekend Science Project

    Science.gov (United States)

    Santos, Karey

    2012-01-01

    Weekend plans...every family has them. Whether it's fishing, swimming, or simply picnicking by the river, water plays a significant role in many recreational endeavors. Encouraging students and their families to use their "scientific eyes" to explore these wonderful wet places is what Weekend Science Project is all about. Weekend Science Project…

  3. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 15; Issue 11. Dawn of Science - The Arab Legacy. T Padmanabhan. Series Article Volume 15 Issue 11 November 2010 pp 1009-1015. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/015/11/1009-1015 ...

  4. Science and Art

    Science.gov (United States)

    Moore, John W.

    2001-10-01

    Science and art diverge in that art usually represents a single individual's conception and viewpoint, even when many others are involved in bringing a work to fruition, whereas science progresses by extending consensus among those knowledgeable in a field. Art usually communicates at an emotional level. It values individual expression and impact on the emotions at the expense of objectivity. Science, especially in its archival record, values objectivity and reproducibility and does not express the imagination and joy of discovery inherent in its practice. This is too bad, because it does not give a realistic picture of how science is really done and because individuality and emotion are inherently more interesting than consensus. Leaving out the personal, emotional side can make science seem boring and pedestrian, when exactly the opposite is true. In teaching science we need to remember that communication always benefits from imagination and esthetic sense. If we present science artistically and imaginatively, as well as objectively and precisely, students will develop a more complete understanding of what science and scientists are about--one that is likely to capture their imaginations, emotions, and best efforts.

  5. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 1. Dawn of Science - The Printed Page. T Padmanabhan. Series Article Volume 16 Issue 1 January 2011 pp 6-11. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/01/0006-0011. Keywords.

  6. Short-Form Science

    Science.gov (United States)

    Murphy, Beth; Hedwall, Melissa; Dirks, Andrew; Stretch, Elizabeth

    2017-01-01

    Reading provides a unique window into the history and nature of science and the norms of scientific communication and supports students in developing critical-reading skills in engaging ways. Effective use of reading promotes a spirit of inquiry and an understanding of science concepts while also addressing expectations of the Common Core State…

  7. Dawn of Science

    Indian Academy of Sciences (India)

    Admin

    early days he studied languages, logic and philosophy and very little of science. He first worked as a teacher in a day school at. Cheshire. During this time, he wrote several books dealing with. English grammar, education and history. Though he never studied science formally, he was always curious about the several new.

  8. Archives: African Health Sciences

    African Journals Online (AJOL)

    Items 1 - 50 of 67 ... Archives: African Health Sciences. Journal Home > Archives: African Health Sciences. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 50 of 67 Items, 1 2 > >> ...

  9. Proceedings - Mathematical Sciences

    Indian Academy of Sciences (India)

    60

    School of Mathematical Sciences, National Institute of Science Education and Research, HBNI,. Bhubaneshwar, Khurda .... method of finding solutions to a problem in Minkowski space from solutions to a re- lated problem in ...... The graph of h has the implicit form cosh2 ˜y = ˜x2 - ˜t2, which is called the time- like hyperbolic ...

  10. The Sound of Science

    Science.gov (United States)

    Merwade, Venkatesh; Eichinger, David; Harriger, Bradley; Doherty, Erin; Habben, Ryan

    2014-01-01

    While the science of sound can be taught by explaining the concept of sound waves and vibrations, the authors of this article focused their efforts on creating a more engaging way to teach the science of sound--through engineering design. In this article they share the experience of teaching sound to third graders through an engineering challenge…

  11. Nuclear Science Centre

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 10. Nuclear Science Centre. N Madhavan. Information and Announcements Volume 2 Issue 10 October 1997 pp 92-96. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/002/10/0092-0096 ...

  12. Ghana Journal of Science

    African Journals Online (AJOL)

    The GHANA JOURNAL OF SCIENCE is published jointly by the Council for Scientific and Industrial Research of Ghana and the Ghana Science Association. It is open to all papers of scientific and technological nature from Ghana and elsewhere, irrespective of the organization to which the authors belong. The topics need ...

  13. Science and Technology Policy

    DEFF Research Database (Denmark)

    Baark, Erik

    1996-01-01

    This paper examines the status of science and technology in Mongolia, and discusses the policy issues which have emerged with the transition to market economy in recent years.......This paper examines the status of science and technology in Mongolia, and discusses the policy issues which have emerged with the transition to market economy in recent years....

  14. Computer Science Experiments

    CERN Document Server

    Walker, Pamela

    2010-01-01

    Computers are more prevalent in our daily lives than ever before, yet many people are unfamiliar with the concepts and technology of computer science. Offering 20 experiments and activities based on computer research, this book aims to expand students' learning experiences in this field by covering key science concepts.

  15. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 3. Dawn of Science - The Role of Modern Medicine. T Padmanabhan. Series Article Volume 16 Issue 3 March 2011 pp 274-278. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/03/0274-0278 ...

  16. Dawn of Science

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 10. Dawn of Science - Geometry Without Figures. T Padmanabhan. Series Article Volume 16 Issue 10 October 2011 pp 950-955. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/10/0950-0955 ...

  17. Science, Evolution, and Creationism

    Science.gov (United States)

    National Academies Press, 2008

    2008-01-01

    How did life evolve on Earth? The answer to this question can help us understand our past and prepare for our future. Although evolution provides credible and reliable answers, polls show that many people turn away from science, seeking other explanations with which they are more comfortable. In the book "Science, Evolution, and…

  18. The Nature of Science

    Science.gov (United States)

    Billingsley, Berry

    2013-01-01

    The view that science and religion are conflicting ways of understanding the world is widely and frequently presented in the media and may be the view held by most children. It is not the only view, however, and there are many scientists who have a religious faith. Usefully perhaps, for those who are interested in science education, examining…

  19. Confronting Ambiguity in Science

    Science.gov (United States)

    Emery, Katherine; Harlow, Danielle; Whitmer, Ali; Gaines, Steven

    2015-01-01

    People are regularly confronted with environmental and science-related issues presented to them in newspapers, on television, or even in their own doctor's office. Often the information they use to inform their decisions on matters of science may be ambiguous and contradictory. This article presents an activity that investigates how students deal…

  20. Zimbabwe Science News

    African Journals Online (AJOL)

    The Zimbabwe Science News has ceased publication. Vol 33, No 1 (1999). DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT Subscription or Fee Access. Table of Contents. Articles. Science-based economic development: The Eureka Factor · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT ...

  1. The Science of Cycling

    Science.gov (United States)

    Crompton, Zoe; Daniels, Shelley

    2014-01-01

    Children are engaged by finding out about science in the real world (Harlen, 2010). Many children will be cyclists or will have seen or heard about the success of British cyclists in the Olympics and the Tour de France. This makes cycling a good hook to draw children into learning science. It is also a good cross-curricular topic, with strong…

  2. Development of inquiry-based planetary science resources for Canadian schools

    Science.gov (United States)

    Osinski, G. R.; Gilbert, A.; Brown, P.

    2011-12-01

    The Centre for Planetary Science and Exploration (CPSX - http://cpsx.uwo.ca) at The University of Western Ontario has initiated a comprehensive outreach and education program focusing on planetary science and exploration. The goal is to use planetary science to raise general interest in science. Currently, the activities being preformed by the centre can be divided into three broad categories: (1) educational/curriculum based activities, (2) outreach/community based activities, and (3) training. The first is where the push for an increase in interest for science is really critical and is the focus here. In partnership with the Thames Valley District School Board and by using inquiry-based teaching methods, students study various topics under the guidance of a CPSX graduate students and faculty. The educational activities that have taken place are all based on the Ontario curriculum and have been developed with the support of the local school board and teachers. An annual teacher workshop provides a hands-on opportunity for the teachers to interact with CPSX members. The first activity to be developed was on meteorite impact craters. The CPSX web page also contains the lesson plans and activity work sheets for this Cratering Activity, as well as additional activities. As the Cratering Activity is available online, teachers can perform the experiment independently or request the support from a CPSX outreach member. The activity is designed with the following structure: (1) The teacher gives a background presentation (provided by CPSX) which describes crater processes throughout our solar system (specifically comparing Earth to other planets), the consequences of impacts on Earth, the origins of impactors (small bodies) in our solar system, and the mechanical process of an impact. (2) The teacher demonstrates an impact event. Students are to make observations in their lab handout, and sketch what they see. (3) Students (either individually or as a group, based on

  3. Creating scientists teaching and assessing science practice for the NGSS

    CERN Document Server

    Moore, Christopher

    2018-01-01

    Teach students to reason like scientists. This practical new book provides a clear framework for helping students develop scientific thinking so they are not just memorizing content but are becoming engaged in the real work scientists do. You'll learn how to teach students to analyse scientific testing, to understand if something caused something else, and to understand the value of evidence. The book offers ideas for lesson plans and assessments and also features reproducible tools and handouts that you can use in the classroom immediately.

  4. NASA science committee appointments

    Science.gov (United States)

    Zielinski, Sarah

    2006-10-01

    NASA Administrator Michael Griffin has made three new appointments to the NASA Advisory Council's (NAC' Science Committee, NASA announced on 22 September. Edward David, president of EED, Inc., and science advisor to the President from 1970 to 1973, will serve as the committee-s chair. Also appointed to the committee were Owen Garriott, a retired scientist astronaut, and Alan Stern, executive director of the Space Science and Engineering Division of the Southwest Research Institute (San Antonio, Tex.). David, Garriott, and Stern-who are among nine new members of the full advisory committee that were announced on 22 September-will replace three members of the Science Committee who resigned in August: Science Committee Chair Charles Kennel (Scripps Institution of Oceanography), Wesley Huntress (Carnegie Institution of Washington), and Eugene Levy (Rice University). The NAC's next public meeting will be held on 12 October at Goddard Space Flight Center in Greenbelt, Md.

  5. Networks in cognitive science.

    Science.gov (United States)

    Baronchelli, Andrea; Ferrer-i-Cancho, Ramon; Pastor-Satorras, Romualdo; Chater, Nick; Christiansen, Morten H

    2013-07-01

    Networks of interconnected nodes have long played a key role in Cognitive Science, from artificial neural networks to spreading activation models of semantic memory. Recently, however, a new Network Science has been developed, providing insights into the emergence of global, system-scale properties in contexts as diverse as the Internet, metabolic reactions, and collaborations among scientists. Today, the inclusion of network theory into Cognitive Sciences, and the expansion of complex-systems science, promises to significantly change the way in which the organization and dynamics of cognitive and behavioral processes are understood. In this paper, we review recent contributions of network theory at different levels and domains within the Cognitive Sciences. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. The master science teacher

    Science.gov (United States)

    Toh, Kok-Aun; Tsoi, Mun-Fie

    2008-11-01

    The dire need of some schools to boost the academic performance of their students inevitably rests with their ability to attract highly qualified teachers. As such, the UK has put in place the Advanced Skills Teacher (AST) scheme, while the US has set the ball rolling in laying down standards for the certification of the master science teacher, to distil the best teachers from this pool of highly qualified science teachers. This article examines some of the practices in the teaching-learning process one would associate with those of master science teachers. It argues for the master science teacher to have a well-developed pedagogical content knowledge rather than be an expert in content knowledge. It argues for the master science teacher to be someone who has moved 'from personal comprehension to preparing for the comprehension of others' (Shulman 1987 Harv. Educ. Rev. 75 1-22).

  7. Journalism and science

    DEFF Research Database (Denmark)

    Meyer, Gitte

    2006-01-01

    that are likely to occur to journalistic attitudes - mirroring changing attitudes in the wider society - towards science and scientific researchers. Two journalistic conventions - those of science transmission and of investigative journalism - are presented and discussed in relation to the present drive towards...... commercialization within the world of science: how are journalists from these different schools of thought likely to respond to the trend of commercialization? Likely journalistic reactions could, while maintaining the authority of the scientific method, be expected to undermine public trust in scientists....... In the long term, this may lead to an erosion of the idea of knowledge as something that cannot simply be reduced o the outcome of negotiation between stakeholders. It is argued that science is likely to be depicted as a fallen angel. This may be countered, it is posited, by science turning human...

  8. The Logic of Science

    DEFF Research Database (Denmark)

    Jensen, Lars Bang

    The problematic this thesis investigates, through a specific kind of structuralism derived from a reading of Michel Foucault, Pierre Bourdieu and Gilles Deleuze, concerns how the subject becomes a science subject and potentially a scientist, with interest and literacy in science. The Logic...... of Science – a vivisection of monsters is thus an exploration of Being and Becoming in relation to Science and its Education. The investigation has been derived from, in, and connected to the Youth-to-Youth Project, a regional bridge building project in Northern Jutland in Denmark. The Youth-to-Youth Project...... (2011-2015) attempts to facilitate contact and provide a different kind of counselling and guidance between youths and youths who are ‘one step ahead’ in their educational trajectory. The meetings between the youths are both social and science subject oriented, and the intention is to establish...

  9. Philosophy of Computer Science

    Directory of Open Access Journals (Sweden)

    Aatami Järvinen

    2014-06-01

    Full Text Available The diversity and interdisciplinary of Computer Sciences, and the multiplicity of its uses in other sciences make it difficult to define them and prescribe how to perform them. Furthermore, also cause friction between computer scientists from different branches. Because of how they are structured, these sciences programs are criticized for not offer an adequate methodological training, or a deep understanding of different research traditions. To collaborate on a solution, some have decided to include in their curricula courses that enable students to gain awareness about epistemology and methodological issues in Computer Science, as well as give meaning to the practice of computer scientists. In this article the needs and objectives of the courses on the philosophy of Computer Science are analyzed, and its structure and management are explained.

  10. Earth Science Informatics - Overview

    Science.gov (United States)

    Ramapriyan, H. K.

    2017-01-01

    Over the last 10-15 years, significant advances have been made in information management, there are an increasing number of individuals entering the field of information management as it applies to Geoscience and Remote Sensing data, and the field of informatics has come to its own. Informatics is the science and technology of applying computers and computational methods to the systematic analysis, management, interchange, and representation of science data, information, and knowledge. Informatics also includes the use of computers and computational methods to support decision making and applications. Earth Science Informatics (ESI, a.k.a. geoinformatics) is the application of informatics in the Earth science domain. ESI is a rapidly developing discipline integrating computer science, information science, and Earth science. Major national and international research and infrastructure projects in ESI have been carried out or are on-going. Notable among these are: the Global Earth Observation System of Systems (GEOSS), the European Commissions INSPIRE, the U.S. NSDI and Geospatial One-Stop, the NASA EOSDIS, and the NSF DataONE, EarthCube and Cyberinfrastructure for Geoinformatics. More than 18 departments and agencies in the U.S. federal government have been active in Earth science informatics. All major space agencies in the world, have been involved in ESI research and application activities. In the United States, the Federation of Earth Science Information Partners (ESIP), whose membership includes over 180 organizations (government, academic and commercial) dedicated to managing, delivering and applying Earth science data, has been working on many ESI topics since 1998. The Committee on Earth Observation Satellites (CEOS)s Working Group on Information Systems and Services (WGISS) has been actively coordinating the ESI activities among the space agencies.The talk will present an overview of current efforts in ESI, the role members of IEEE GRSS play, and discuss

  11. Value of Fundamental Science

    Science.gov (United States)

    Burov, Alexey

    Fundamental science is a hard, long-term human adventure that has required high devotion and social support, especially significant in our epoch of Mega-science. The measure of this devotion and this support expresses the real value of the fundamental science in public opinion. Why does fundamental science have value? What determines its strength and what endangers it? The dominant answer is that the value of science arises out of curiosity and is supported by the technological progress. Is this really a good, astute answer? When trying to attract public support, we talk about the ``mystery of the universe''. Why do these words sound so attractive? What is implied by and what is incompatible with them? More than two centuries ago, Immanuel Kant asserted an inseparable entanglement between ethics and metaphysics. Thus, we may ask: which metaphysics supports the value of scientific cognition, and which does not? Should we continue to neglect the dependence of value of pure science on metaphysics? If not, how can this issue be addressed in the public outreach? Is the public alienated by one or another message coming from the face of science? What does it mean to be politically correct in this sort of discussion?

  12. Globalization and Science Education

    Science.gov (United States)

    Bencze, J. Lawrence; Carter, Lyn; Chiu, Mei-Hung; Duit, Reinders; Martin, Sonya; Siry, Christina; Krajcik, Joseph; Shin, Namsoo; Choi, Kyunghee; Lee, Hyunju; Kim, Sung-Won

    2013-06-01

    Processes of globalization have played a major role in economic and cultural change worldwide. More recently, there is a growing literature on rethinking science education research and development from the perspective of globalization. This paper provides a critical overview of the state and future development of science education research from the perspective of globalization. Two facets are given major attention. First, the further development of science education as an international research domain is critically analyzed. It seems that there is a predominance of researchers stemming from countries in which English is the native language or at least a major working language. Second, the significance of rethinking the currently dominant variants of science instruction from the perspectives of economic and cultural globalization is given major attention. On the one hand, it is argued that processes concerning globalization of science education as a research domain need to take into account the richness of the different cultures of science education around the world. At the same time, it is essential to develop ways of science instruction that make students aware of the various advantages, challenges and problems of international economic and cultural globalization.

  13. Style in science communication.

    Science.gov (United States)

    Bucchi, Massimiano

    2013-11-01

    There is little doubt that during the past few decades science communication efforts aimed at non-expert audiences have increased in quantity and intensity on a global scale. Public engagement and outreach activities have now become a routine - when not a prominent - feature for several research institutions in Europe. However, it would be difficult for both scholars and those involved in science communication to agree on the impact of these activities, on the long-term implications of the 'science communication movement' and on the indicators we should develop and employ in order to assess impact. The paper argues that quality is a relevant issue and challenge for contemporary science communication. Style is relevant to addressing that challenge, insofar as it relates to discussions about how to strengthen the quality of science communication, suggesting a different perspective other than the traditional normative/prescriptive framework. The notion of style also fruitfully connects the debate on science communication with a rich tradition of studies in the history and sociology of science.

  14. Social Sciences and Sustainability

    Directory of Open Access Journals (Sweden)

    Shu-Kun Lin

    2011-09-01

    Full Text Available At the time when the journal Sustainability [1] was launched, as a chemist and a scientist, I started to believe that social sciences may be more important to make humans sustainable. The broad journal title Social Sciences presents the opportunity for all social science scholars to have integrated consideration regarding the sustainability of humanity, because I am sure that science and technology alone cannot help. Science and technology may have in fact been contributing to accelerate the depletion of nonrenewable natural resources and putting human sustainability at risk since the industrial revolution about 150 years ago. I hope all intellectuals studying anthropology, archaeology, administration, communication, criminology, economics, education, government, linguistics, international relations, politics, sociology and, in some contexts, geography, history, law, and psychology publish with us to seek a solution to sustain humanity. Sustainability itself will also be a main topic of the journal Social Sciences. In addition to this integrated forum for social sciences, more topic specific journals, such as the already publishing Societies [2], will be launched. [...

  15. Science on stage

    CERN Multimedia

    2005-01-01

    During the opening ceremony, the audience was dazzled by a juggling show involving dramatic light effects. They also took away with them a teacher's sheet explaining some of the scientific concepts involved in juggling. Science teachers can sometimes be quite humorous when it comes to explaining serious matters, as those who took part in the 'Science on Stage' festival held at CERN from 21 to 25 November were able to see for themselves. The 500 or so participants from 27 different countries, mostly science teachers but also some university lecturers, science outreach specialists and students, had the opportunity to share their experience of the teaching of science. They also attended presentations and shows, took part in workshops and visited a fair with stands offering ideas on how to make school science lessons more appealing. The festival, organised by the EIROforum (a partnership between CERN, EFDA, ESA, ESO, EMBL, ESRF and ILL), marked the end of two years of projects for the promotion of science in vir...

  16. USSR Report, Life Sciences, Biomedical and Behavioral Sciences

    National Research Council Canada - National Science Library

    1984-01-01

    Partial Contents: Life Sciences, Biomedical and Behavioral Sciences, Aerospace Medicine, Argotechnology, Biochemistry, Bionics, Biophysics, Biotechnology, Epidemiology, Genetics, Human Factors, Immunology, Laser...

  17. Science, Society and Policy

    Science.gov (United States)

    White, K. S.; Teich, A. H.

    2010-12-01

    Apart from the journals they produce, scientific societies play an important role in communicating scientific findings and norms to the broader society. The American Association for the Advancement of Science (AAAS) includes among its goals to promote and defend the integrity of science and its use; provide a voice for science on societal issues; promote the responsible use of science in public policy; and increase public engagement with science and technology. AAAS websites and programs, including Communicating Science (www.aaas.org/communicatingscience), Working with Congress (http://www.aaas.org/spp/cstc/wwc/book.htm) and ScienceCareers.org (http://sciencecareers.sciencemag.org), provide tools for scientists to become more directly engaged in effectively communicating their findings and involved in the policy process. Education programs work to build the next generation of scientists and a science-literate public. To bridge the current communication gap between scientists, the public and policymakers, AAAS, like other scientific societies, maintains policy and outreach programs with limited budgets and staff. AAAS works to engage policymakers and provide scientific underpinning to key issues through congressional briefings, meetings, policy briefs, and media outreach. AAAS responds to challenges to accepted scientific findings and processes through op-eds, letters to government officials, resolutions, and Board statements. Some of these initiatives occur on a local level in partnership with local civic leaders, whose endorsement makes them more powerful. On a national scale, they assure that the voice of science is included in the debate. The changing media landscape presents opportunities and challenges for future AAAS endeavors.

  18. 76 FR 6163 - Subcommittee on Forensic Science; Committee on Science; National Science and Technology Council

    Science.gov (United States)

    2011-02-03

    ... No: 2011-2440] OFFICE OF SCIENCE AND TECHNOLOGY POLICY Subcommittee on Forensic Science; Committee on... Sciences 2009 report: ``Strengthening Forensic Science in the United States: A Path Forward'' ( http://www.nap.edu/catalog.php?record_id=12589#toc ). SUMMARY: The Subcommittee on Forensic Science (SoFS) of the...

  19. Pre-Service Science Teachers' Cognitive Structures Regarding Science, Technology, Engineering, Mathematics (STEM) and Science Education

    Science.gov (United States)

    Hacioglu, Yasemin; Yamak, Havva; Kavak, Nusret

    2016-01-01

    The aim of this study is to reveal pre-service science teachers' cognitive structures regarding Science, Technology, Engineering, Mathematics (STEM) and science education. The study group of the study consisted of 192 pre-service science teachers. A Free Word Association Test (WAT) consisting of science, technology, engineering, mathematics and…

  20. Third National Women's Science Congress

    Indian Academy of Sciences (India)

    2010-11-08

    Nov 8, 2010 ... The Science Congress would cover the entire spectrum of science, engineering and technology, both ... Geography, Archaeology, EarthSciences, Ecology, Biodiversity, Environment (Vasundariyam); (8) ... theforefrontofscience& technology.inallaspects ofteaching, researchandindustrialpractices. The first ...

  1. PubSCIENCE

    CERN Document Server

    United States. Department of Energy. Office of Scientific and Technical Information

    PubSCIENCE, a component of EnergyFiles, indexes 1,000 scientific and technical journals. It contains over one million multi-source journal citations dating back over 25 years from DOE's Energy Science and Technology Database. The focus of PubSCIENCE is on those journals where DOE researchers report their scientific discoveries. Frequency of contributions by DOE-sponsored researchers to scientific journals has been analyzed to prioritize data collection efforts. OSTI partners with participating publishers to provide information that is both relevant and useful to the DOE scientific community as well as information that was developed as the result of government sponsored R&D.

  2. Culture and Cognitive Science

    OpenAIRE

    Michael Cole

    2003-01-01

    The purpose of this paper is to review the way in which cultural contributions to human nature have been treated within the field of  cognitive science. I was initially motivated to write about this topic when invited to give a talk to a Cognitive Science department at a sister university in California a few years ago. My goal, on that occasion, was to convince my audience, none of whom were predisposed to considering culture an integral part of cognitive science, that they would indeed benef...

  3. COMPUTATIONAL SCIENCE CENTER

    Energy Technology Data Exchange (ETDEWEB)

    DAVENPORT, J.

    2005-11-01

    The Brookhaven Computational Science Center brings together researchers in biology, chemistry, physics, and medicine with applied mathematicians and computer scientists to exploit the remarkable opportunities for scientific discovery which have been enabled by modern computers. These opportunities are especially great in computational biology and nanoscience, but extend throughout science and technology and include, for example, nuclear and high energy physics, astrophysics, materials and chemical science, sustainable energy, environment, and homeland security. To achieve our goals we have established a close alliance with applied mathematicians and computer scientists at Stony Brook and Columbia Universities.

  4. Play or science?

    DEFF Research Database (Denmark)

    Lieberoth, Andreas; Pedersen, Mads Kock; Sherson, Jacob

    2015-01-01

    Crowdscience games may hold unique potentials as learning opportunities compared to games made for fun or education. They are part of an actual science problem solving process: By playing, players help scientists, and thereby interact with real continuous research processes. This mixes the two...... worlds of play and science in new ways. During usability testing we discovered that users of the crowdscience game Quantum Dreams tended to answer questions in game terms, even when directed explicitly to give science explanations. We then examined these competing frames of understanding though a mixed...

  5. The Next Great Science

    Science.gov (United States)

    Hodges, K. V.

    2007-12-01

    Earth science --- when defined as the study of all biological, chemical, and physical processes that interact to define the behavior of the Earth system --- has direct societal relevance equal to or greater than that any other branch of science. However, "geology", "geoscience", and "Earth science" departments are contracting at many universities and even disappearing at some. This irony speaks volumes about the limitations of the traditional university structure that partitions educational and research programs into specific disciplines, each housed in its own department. Programs that transcend disciplinary boundaries are difficult to fit into the traditional structure and are thus highly vulnerable to threats such as chronic underfunding by university administrations, low enrollments in more advanced subjects, and being largely forgotten during capital campaigns. Dramatic improvements in this situation will require a different way of thinking about earth science programs by university administrations. As Earth scientists, our goal must not be to protect "traditional" geology departments, but rather to achieve a sustainable programmatic future for broader academic programs that focus on Earth evolution from past, present, and future perspectives. The first step toward meeting this goal must be to promote a more holistic definition of Earth science that includes modes of inquiry more commonly found in engineering and social science departments. We must think of Earth science as a meta-discipline that includes core components of physics, geology, chemistry, biology, and the emerging science of complexity. We must recognize that new technologies play an increasingly important role in our ability to monitor global environmental change, and thus our educational programs must include basic training in the modes of analysis employed by engineers as well as those employed by scientists. One of the most important lessons we can learn from the engineering community is the

  6. Public Engagement with Science

    DEFF Research Database (Denmark)

    Irwin, Alan

    2014-01-01

    not problematising ‘the public’, taking values seriously and instead educating ‘the experts’, and recognising both the ‘legitimacy of wider concerns’ and the ‘democratic imperative’. Public Engagement with Science as strategy is building upon a normative commitment to the idea of democratic science policy...... for dialogue exercises look microscopic against the backdrop of global science and its governance. Maybe it has been over-promised what such public engagement exercises can deliver. We can safely conclude that, despite all the ‘from deficit to democracy’ talk, no such easy shift has been made. At best, partial...

  7. Computer science handbook

    CERN Document Server

    Tucker, Allen B

    2004-01-01

    Due to the great response to the famous Computer Science Handbook edited by Allen B. Tucker, … in 2004 Chapman & Hall/CRC published a second edition of this comprehensive reference book. Within more than 70 chapters, every one new or significantly revised, one can find any kind of information and references about computer science one can imagine. … All in all, there is absolute nothing about computer science that can not be found in the encyclopedia with its 110 survey articles …-Christoph Meinel, Zentralblatt MATH

  8. Science, conscience, consciousness.

    Science.gov (United States)

    Hennig, Boris

    2010-01-01

    Descartes' metaphysics lays the foundation for the special sciences, and the notion of consciousness ("conscientia") belongs to metaphysics rather than to psychology. I argue that as a metaphysical notion, "consciousness" refers to an epistemic version of moral conscience. As a consequence, the activity on which science is based turns out to be conscientious thought. The consciousness that makes science possible is a double awareness: the awareness of what one is thinking, of what one should be doing, and of the possibility of a gap between the two.

  9. Empirical Philosophy of Science

    DEFF Research Database (Denmark)

    Mansnerus, Erika; Wagenknecht, Susann

    2015-01-01

    The book examines the emerging approach of using qualitative methods, such as interviews and field observations, in the philosophy of science. Qualitative methods are gaining popularity among philosophers of science as more and more scholars are resorting to empirical work in their study...... of scientific practices. At the same time, the results produced through empirical work are quite different from those gained through the kind of introspective conceptual analysis more typical of philosophy. This volume explores the benefits and challenges of an empirical philosophy of science and addresses...

  10. Science Communication in Denmark

    DEFF Research Database (Denmark)

    Busch, Henrik

    2005-01-01

    This paper was presented during the author?s visit at the Faculty of Human Development of the University of Kobe . The paper is intended to provide the knowledge about science communication in the Nordic countries (in particular in Denmark). The focus in the paper is on (i) examples of new...... and innovative modes of science communication in Denmark and (ii) educational programs for science communicators. Furthermore, emphasis is on the pedagogical ideas behind the initiatives, rather than on thorough descriptions of structures, curricula and evaluations of the projects....

  11. Coping with Science

    DEFF Research Database (Denmark)

    Ricard, Lykke Margot

    2003-01-01

    Life of Science, edited by Lykke Margot Ricard and Robin Engelhardt. Learning Lab Denmark, Copenhagen, pages 39-45. 2003 Short description: What makes children think about scientific inventions? In this case it was watching the news and listing to parents conversation that made a 12-year old...... schoolboy write an essay on the theme: ?The world would be a better place to live in if?!? Abstract: Science has a long tradition for emphasizing objectivity, but it is the emotional impact of science that makes children interested. Metaphors and personal experiences of the scientist can be a useful...

  12. JPRS Report Science & Technology USSR: Life Sciences.

    Science.gov (United States)

    1990-07-09

    Allogenic Tumors Extracts on Development, in Calves, of Experimental Infection by Bovine Leukemia Virus [R. A. Kukayn, L. I. Nagayeva, et al...indirect immunofluorescence revealed a variegated pat- tern of respiratory viruses ( parainfluenza , respiratory- syncytial, influenza B, adenovirus...USSR Academy of Sciences] [Abstract] Transgenic mice (3 with bovine growth hor- mone genome and 4 with fragments of DNA of adeno- virus SSA7) and

  13. JPRS Report, Science & Technology, USSR: Life Sciences.

    Science.gov (United States)

    1987-08-04

    kidneys of the newborn ones over those of the small children donors. This method makes it possible to preserve glomerular filtration, reabsorptional and...naloxone or bilateral cervical vagotomy. It was concluded that the above effects are reflex in nature; their physiological meaning remains unclear...Ukrainian SSR Academy of Sciences, Kiev] [Abstract! Electrophysi-olQgical studies with the superior cervical ganglia of rabbits and rats demonstrated

  14. The Theoretical Science of Research

    OpenAIRE

    Subbarayan Peri

    2013-01-01

    The science of research is unique among sciences in many respects. All other sciences are reared by it, but it has never been viewed as a science so far in this world. Had it been developed as an independent science, the world would have advanced by some centuries than what it did and had. The science of research is an integral part of the emerging ‗learning science‘ along with it counter-parts the science of education. Every systematic science has its elements i.e. paraphernalia —assumption...

  15. Perspectives in Pig Science

    NARCIS (Netherlands)

    Wiseman, J.; Varley, M.A.; Kemp, B.

    2003-01-01

    Perspectives in Pig Science features a collection of papers on five key areas: breeding and genetics; management, marketing and meat quality; health and welfare; reproduction and reproductive management; nutrition.

  16. Theoretical Computer Science

    DEFF Research Database (Denmark)

    2002-01-01

    The proceedings contains 8 papers from the Conference on Theoretical Computer Science. Topics discussed include: query by committee, linear separation and random walks; hardness results for neural network approximation problems; a geometric approach to leveraging weak learners; mind change...

  17. Early Adolescence: Snowy Science.

    Science.gov (United States)

    Padilla, Michael

    1983-01-01

    Middle junior high school science activities focusing on snow are suggested. These include observing snowflakes, measuring snow, examining relationship between snow and temperature, and activities related to drifting snow and snow fences. (JN)

  18. Fundamentals of electrochemical science

    CERN Document Server

    Oldham, Keith

    1993-01-01

    Key Features* Deals comprehensively with the basic science of electrochemistry* Treats electrochemistry as a discipline in its own right and not as a branch of physical or analytical chemistry* Provides a thorough and quantitative description of electrochemical fundamentals

  19. Quantum Social Science

    Science.gov (United States)

    Haven, Emmanuel; Khrennikov, Andrei

    2013-01-01

    Preface; Part I. Physics Concepts in Social Science? A Discussion: 1. Classical, statistical and quantum mechanics: all in one; 2. Econophysics: statistical physics and social science; 3. Quantum social science: a non-mathematical motivation; Part II. Mathematics and Physics Preliminaries: 4. Vector calculus and other mathematical preliminaries; 5. Basic elements of quantum mechanics; 6. Basic elements of Bohmian mechanics; Part III. Quantum Probabilistic Effects in Psychology: Basic Questions and Answers: 7. A brief overview; 8. Interference effects in psychology - an introduction; 9. A quantum-like model of decision making; Part IV. Other Quantum Probabilistic Effects in Economics, Finance and Brain Sciences: 10. Financial/economic theory in crisis; 11. Bohmian mechanics in finance and economics; 12. The Bohm-Vigier Model and path simulation; 13. Other applications to economic/financial theory; 14. The neurophysiological sources of quantum-like processing in the brain; Conclusion; Glossary; Index.

  20. Philosophy of social science

    Directory of Open Access Journals (Sweden)

    Charles Vergeer

    2015-12-01

    Full Text Available Mark Risjord. Philosophy of Social Science. A Contemporary Introduction. Serie: Routledge Contemporary Introductions to Philosophy. New York and London: Routledge, 2014, 288 p., €42,75. ISBN 978 0 415 89825 6