WorldWideScience

Sample records for psd map room

  1. PSD Increment Consumption Guidance

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  2. PSD Increment Consumption Question

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  3. Remote Laser Diffraction PSD Analyzer

    Energy Technology Data Exchange (ETDEWEB)

    Batcheller, Thomas Aquinas; Huestis, Gary Michael; Bolton, Steven Michael

    2000-06-01

    Particle size distribution (PSD) analysis of radioactive slurry samples were obtained using a modified "off-the-shelf" classical laser light scattering particle size analyzer. A Horiba Instruments Inc. Model La-300 PSD analyzer, which has a 0.1 to 600 micron measurement range, was modified for remote application in a "hot cell" (gamma radiation) environment. The general details of the modifications to this analyzer are presented in this paper. This technology provides rapid and simple PSD analysis, especially down in the fine and microscopic particle size regime. Particle size analysis of these radioactive slurries down in this smaller range was not achievable - making this technology far superior than the traditional methods used previously. Remote deployment and utilization of this technology is in an exploratory stage. The risk of malfunction in this radiation environment is countered by gaining of this tremendously useful fundamental engineering data. Successful acquisition of this data, in conjunction with other characterization analyses, provides important information that can be used in the myriad of potential radioactive waste management alternatives.

  4. PSD Determination, Portland Cement Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  5. Video observation to map hand contact and bacterial transmission in operating rooms.

    Science.gov (United States)

    Rowlands, John; Yeager, Mark P; Beach, Michael; Patel, Hetal M; Huysman, Bridget C; Loftus, Randy W

    2014-07-01

    Hand hygiene (HH) is considered a primary intervention to avoid transmission of bacteria in health care settings and to prevent health care-associated infections. Despite efforts to decrease the incidence of health care-associated infections by improving HH, HH compliance rates vary widely depending on the hospital environment. We used intraoperative video observation to map temporal patterns of anesthesia provider hand contact with anesthesia work environment (AWE) surfaces and to assess HH compliance. Serial bacterial cultures of high contact objects were subsequently used to characterize bacterial transmission over time. Using World Health Organization criteria, we found a large number of HH opportunities and a low rate of HH compliance by anesthesia providers (mean, 2.9%). We observed an inverse correlation between provider hand hygiene compliance during induction and emergence from anesthesia (3.2% and 4.1%, respectively) and the magnitude of AWE surface contamination (103 and 147 CFU, respectively) at these time points. We found no correlation between frequency of hand contact with the AWE and bacterial contamination. Compliance with current HH recommendations by anesthesia providers is not feasible. However, there does appear to be a correlation between HH compliance rates and bacterial contamination of the AWE, an observation that should stimulate further work to design new methods for control of bacterial transmission in operating rooms. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

  6. Marshall Space Flight Center Propulsion Systems Department (PSD) KM Initiative

    Science.gov (United States)

    Caraccioli, Paul; Varnadoe, Tom; McCarter, Mike

    2006-01-01

    NASA Marshall Space Flight Center s Propulsion Systems Department (PSD) is four months into a fifteen month Knowledge Management (KM) initiative to support enhanced engineering decision making and analyses, faster resolution of anomalies (near-term) and effective, efficient knowledge infused engineering processes, reduced knowledge attrition, and reduced anomaly occurrences (long-term). The near-term objective of this initiative is developing a KM Pilot project, within the context of a 3-5 year KM strategy, to introduce and evaluate the use of KM within PSD. An internal NASA/MSFC PSD KM team was established early in project formulation to maintain a practitioner, user-centric focus throughout the conceptual development, planning and deployment of KM technologies and capabilities with in the PSD. The PSD internal team is supported by the University of Alabama's Aging Infrastructure Systems Center Of Excellence (AISCE), Intergraph Corporation, and The Knowledge Institute. The principle product of the initial four month effort has been strategic planning of PSD KM implementation by first determining the "as is" state of KM capabilities and developing, planning and documenting the roadmap to achieve the desired "to be" state. Activities undertaken to support the planning phase have included data gathering; cultural surveys, group work-sessions, interviews, documentation review, and independent research. Assessments and analyses have been performed including industry benchmarking, related local and Agency initiatives, specific tools and techniques used and strategies for leveraging existing resources, people and technology to achieve common KM goals. Key findings captured in the PSD KM Strategic Plan include the system vision, purpose, stakeholders, prioritized strategic objectives mapped to the top ten practitioner needs and analysis of current resource usage. Opportunities identified from research, analyses, cultural/KM surveys and practitioner interviews include

  7. Structure of the first PDZ domain of human PSD-93

    DEFF Research Database (Denmark)

    Fiorentini, Monica; Nielsen, Ann Kallehauge; Kristensen, Ole

    2009-01-01

    the PDZ1-PDZ2 linker region at the extreme C-terminus of PDZ1, implying that the oligomerization that is observed is not of biological significance in full-length PSD-93. Comparison of the structures of the binding cleft of PSD-93 PDZ1 with the previously reported structures of PSD-93 PDZ2 and PDZ3...

  8. Some upper and lower bounds on PSD-rank

    NARCIS (Netherlands)

    T. J. Lee (Troy); Z. Wei (Zhaohui); R. M. de Wolf (Ronald)

    2014-01-01

    textabstractPositive semidefinite rank (PSD-rank) is a relatively new quantity with applications to combinatorial optimization and communication complexity. We first study several basic properties of PSD-rank, and then develop new techniques for showing lower bounds on the PSD-rank. All of these

  9. Some upper and lower bounds on PSD-rank

    NARCIS (Netherlands)

    Lee, T.; Wei, Z.; de Wolf, R.

    Positive semidefinite rank (PSD-rank) is a relatively new complexity measure on matrices, with applications to combinatorial optimization and communication complexity. We first study several basic properties of PSD-rank, and then develop new techniques for showing lower bounds on the PSD-rank. All

  10. PSD Applicability: Industrial Scrap Processing Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  11. Baseline Value for PSD Increment Consumption

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  12. PSD Applicability Determination - Southwestern Public Service Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  13. PSD Determination - Consolidated Edison of New York

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  14. PSD Determination Cabot Corporation - Fuel Conversion

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  15. PSD Applicability Pulp and Paper Mill

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. Turbine Enhancements and PSD Applicability -- Holcomb Station

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  17. Posttranslational Modifications Regulate the Postsynaptic Localization of PSD-95.

    Science.gov (United States)

    Vallejo, Daniela; Codocedo, Juan F; Inestrosa, Nibaldo C

    2017-04-01

    The postsynaptic density (PSD) consists of a lattice-like array of interacting proteins that organizes and stabilizes synaptic receptors, ion channels, structural proteins, and signaling molecules required for normal synaptic transmission and synaptic function. The scaffolding and hub protein postsynaptic density protein-95 (PSD-95) is a major element of central chemical synapses and interacts with glutamate receptors, cell adhesion molecules, and cytoskeletal elements. In fact, PSD-95 can regulate basal synaptic stability as well as the activity-dependent structural plasticity of the PSD and, therefore, of the excitatory chemical synapse. Several studies have shown that PSD-95 is highly enriched at excitatory synapses and have identified multiple protein structural domains and protein-protein interactions that mediate PSD-95 function and trafficking to the postsynaptic region. PSD-95 is also a target of several signaling pathways that induce posttranslational modifications, including palmitoylation, phosphorylation, ubiquitination, nitrosylation, and neddylation; these modifications determine the synaptic stability and function of PSD-95 and thus regulate the fates of individual dendritic spines in the nervous system. In the present work, we review the posttranslational modifications that regulate the synaptic localization of PSD-95 and describe their functional consequences. We also explore the signaling pathways that induce such changes.

  18. North Coast Unified Air Quality Management District: PSD Delegation Agreements

    Science.gov (United States)

    Agreements for Partial Delegation of the Federal Prevention of Significant Deterioration (PSD) Program Set Forth in 40 CPR 52.21 by the United States Environmental Protection Agency, Region 9 to the North Coast Unified Air Quality Management District.

  19. Psd1 Effects on Candida albicans Planktonic Cells and Biofilms

    Directory of Open Access Journals (Sweden)

    Sónia Gonçalves

    2017-06-01

    Full Text Available Candida albicans is an important human pathogen, causing opportunistic infections. The adhesion of planktonic cells to a substrate is the first step for biofilm development. The antimicrobial peptide (AMP Psd1 is a defensin isolated from Pisum sativum seeds. We tested the effects of this AMP on C. albicans biofilms and planktonic cells, comparing its activity with amphotericin B and fluconazole. Three C. albicans variants were studied, one of them a mutant deficient in glucosylceramide synthase, conferring resistance to Psd1 antifungal action. Atomic force microscopy (AFM was used to assess morphological and biomechanical changes on fungal cells. Surface alterations, with membrane disruption and leakage of cellular contents, were observed. Cytometry assays and confocal microscopy imaging showed that Psd1 causes cell death, in a time and concentration-dependent manner. These results demonstrate Psd1 pleiotropic action against a relevant fungal human pathogen, suggesting its use as natural antimycotic agent.

  20. Marshall Space Flight Center Propulsion Systems Department (PSD) Knowledge Management (KM) Initiative

    Science.gov (United States)

    Caraccioli, Paul; Varnedoe, Tom; Smith, Randy; McCarter, Mike; Wilson, Barry; Porter, Richard

    2006-01-01

    NASA Marshall Space Flight Center's Propulsion Systems Department (PSD) is four months into a fifteen month Knowledge Management (KM) initiative to support enhanced engineering decision making and analyses, faster resolution of anomalies (near-term) and effective, efficient knowledge infused engineering processes, reduced knowledge attrition, and reduced anomaly occurrences (long-term). The near-term objective of this initiative is developing a KM Pilot project, within the context of a 3-5 year KM strategy, to introduce and evaluate the use of KM within PSD. An internal NASA/MSFC PSD KM team was established early in project formulation to maintain a practitioner, user-centric focus throughout the conceptual development, planning and deployment of KM technologies and capabilities within the PSD. The PSD internal team is supported by the University of Alabama's Aging Infrastructure Systems Center of Excellence (AISCE), lntergraph Corporation, and The Knowledge Institute. The principle product of the initial four month effort has been strategic planning of PSD KNI implementation by first determining the "as is" state of KM capabilities and developing, planning and documenting the roadmap to achieve the desired "to be" state. Activities undertaken to suppoth e planning phase have included data gathering; cultural surveys, group work-sessions, interviews, documentation review, and independent research. Assessments and analyses have beon pedormed including industry benchmarking, related local and Agency initiatives, specific tools and techniques used and strategies for leveraging existing resources, people and technology to achieve common KM goals. Key findings captured in the PSD KM Strategic Plan include the system vision, purpose, stakeholders, prioritized strategic objectives mapped to the top ten practitioner needs and analysis of current resource usage. Opportunities identified from research, analyses, cultural1KM surveys and practitioner interviews include

  1. A Comparison of PSD Enveloping Methods for Nonstationary Vibration

    Science.gov (United States)

    Irvine, Tom

    2015-01-01

    There is a need to derive a power spectral density (PSD) envelope for nonstationary acceleration time histories, including launch vehicle data, so that components can be designed and tested accordingly. This paper presents the results of the three methods for an actual flight accelerometer record. Guidelines are given for the application of each method to nonstationary data. The method can be extended to other scenarios, including transportation vibration.

  2. Hypoxia Room

    Data.gov (United States)

    Federal Laboratory Consortium — The Hypoxia Room is a 8x8x8 ft. clear vinyl plastic and aluminum frame construction enclosure located within USAREIM laboratory 028. The Hypoxia Room (manufactured...

  3. Room Acoustics

    Science.gov (United States)

    Kuttruff, Heinrich; Mommertz, Eckard

    The traditional task of room acoustics is to create or formulate conditions which ensure the best possible propagation of sound in a room from a sound source to a listener. Thus, objects of room acoustics are in particular assembly halls of all kinds, such as auditoria and lecture halls, conference rooms, theaters, concert halls or churches. Already at this point, it has to be pointed out that these conditions essentially depend on the question if speech or music should be transmitted; in the first case, the criterion for transmission quality is good speech intelligibility, in the other case, however, the success of room-acoustical efforts depends on other factors that cannot be quantified that easily, not least it also depends on the hearing habits of the listeners. In any case, absolutely "good acoustics" of a room do not exist.

  4. Prevention of Significant Deterioration (PSD) Emission Thresholds for Fountain Foundry

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  5. Memo on PSD Applicability Determination for an Ethanol Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  6. National Asphalt Pavement Association Questions and Answers on PSD

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  7. Request for Guidance on PSD Applicability Determinations for Boiler Emissions

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  8. Applicability of PSD to Pennsylvania Power and Light Auxiliary Boiler

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  9. Valero Hydrocarbons BACT Analysis, PSD-TX-746

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  10. USDA Forest Service, Rocky Mountain Region PSD Permit Completeness Determination

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  11. PSD Applicability - Public Service Electric and Gas Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  12. Applicability of EPA's PSD Regulations to Floating Seafood Processors

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  13. Applicability of PSD to the Consolidated Edison Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  14. Appeal Procedures for PSD Permits Under The Consolidated Permit Regulations

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  15. PSD Determination of Applicability - UMD Coal Gasification Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. Determining PSD Applicability Thresholds for Gas Turbine Based Facilities

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  17. Applicability of PSD to Carter Oil Company Pilot Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  18. Union Carbide Chemicals and Plastics Company, Inc PSD Applicability

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  19. VID22 is required for transcriptional activation of the PSD2 gene in the yeast Saccharomyces cerevisiae.

    Science.gov (United States)

    Miyata, Non; Miyoshi, Takuya; Yamaguchi, Takanori; Nakazono, Toshimitsu; Tani, Motohiro; Kuge, Osamu

    2015-12-15

    Phosphatidylethanolamine (PE) in the yeast Saccharomyces cerevisiae is synthesized through decarboxylation of phosphatidylserine (PS), catalysed by PS decarboxylase 1 (Psd1p) and 2 (Psd2p) and the cytidine 5'-diphosphate (CDP)-ethanolamine (CDP-Etn) pathway. PSD1 null (psd1Δ) and PSD2 null (psd2Δ) mutants are viable in a synthetic minimal medium, but a psdpsd2Δ double mutant exhibits Etn auxotrophy, which is incorporated into PE through the CDP-Etn pathway. We have previously shown that psd1Δ is synthetic lethal with deletion of VID22 (vid22Δ) [Kuroda et al. (2011) Mol. Microbiol. 80: , 248-265]. In the present study, we found that vid22Δ mutant exhibits Etn auxotrophy under PSD1-depressed conditions. Deletion of VID22 in wild-type and PSD1-depressed cells caused partial defects in PE formation through decarboxylation of PS. The enzyme activity of PS decarboxylase in an extract of vid22Δ cells was ∼70% of that in wild-type cells and similar to that in psd2Δ cells and the PS decarboxylase activity remaining in the PSD1-depressed cells became almost negligible with deletion of VID22. Thus, the vid22Δ mutation was suggested to cause a defect in the Psd2p activity. Furthermore, vid22Δ cells were shown to be defective in expression of the PSD2 gene tagged with 6×HA, the defect being ameliorated by replacement of the native promoter of the PSD2 gene with a CYC1 promoter. In addition, an α-galactosidase reporter assay revealed that the activity of the promoter of the PSD2 gene in vid22Δ cells was ∼5% of that in wild-type cells. These results showed that VID22 is required for transcriptional activation of the PSD2 gene. © 2015 Authors; published by Portland Press Limited.

  20. Active Well Counting Using New PSD Plastic Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Hausladen, Paul [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Newby, Jason [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); McElroy, Robert Dennis [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-11-01

    This report presents results and analysis from a series of proof-of-concept measurements to assess the suitability of segmented detectors constructed from Eljen EJ-299-34 PSD-plastic scintillator with pulse-shape discrimination capability for the purposes of quantifying uranium via active neutron coincidence counting. Present quantification of bulk uranium materials for international safeguards and domestic materials control and accounting relies on active neutron coincidence counting systems, such as the Active Well Coincidence Counter (AWCC) and the Uranium Neutron Coincidence Collar (UNCL), that use moderated He-3 proportional counters along with necessarily low-intensity 241Am(Li) neutron sources. Scintillation-based fast-neutron detectors are a potentially superior technology to the existing AWCC and UNCL designs due to their spectroscopic capability and their inherently short neutron coincidence times that largely eliminate random coincidences and enable interrogation by stronger sources. One of the past impediments to the investigation and adoption of scintillation counters for the purpose of quantifying bulk uranium was the commercial availability of scintillators having the necessary neutron-gamma pulse-shape discrimination properties only as flammable liquids. Recently, Eljen EJ-299-34 PSD-plastic scintillator became commercially available. The present work is the first assessment of an array of PSD-plastic detectors for the purposes of quantifying bulk uranium. The detector panel used in the present work was originally built as the focal plane for a fast-neutron imager, but it was repurposed for the present investigation by construction of a stand to support the inner well of an AWCC immediately in front of the detector panel. The detector panel and data acquisition of this system are particularly well suited for performing active-well fast-neutron counting of LEU and HEU samples because the active detector volume is solid, the 241Am(Li) interrogating

  1. 75 FR 70254 - PSD and Title V Permitting Guidance for Greenhouse Gases

    Science.gov (United States)

    2010-11-17

    ... AGENCY PSD and Title V Permitting Guidance for Greenhouse Gases AGENCY: Environmental Protection Agency... the EPA has posted its guidance titled, ``PSD and Title V Permitting Guidance for Greenhouse Gases... for Greenhouse Gases.'' This document has been determined to be an EPA Significant Guidance Document...

  2. 76 FR 23489 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR...

    Science.gov (United States)

    2011-04-27

    ..., ``Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Reconsideration of... AGENCY 40 CFR Parts 51 and 52 RIN 2060-AQ73 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Reconsideration of Inclusion of Fugitive Emissions; Interim Rule; Stay...

  3. 75 FR 6823 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR...

    Science.gov (United States)

    2010-02-11

    ... AGENCY 40 CFR Parts 51 and 52 RIN 2060-AP73 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Reconsideration of Inclusion of Fugitive Emissions; Proposal for... emissions requirements in the federal Prevention of Significant Deterioration (PSD) program published in the...

  4. 75 FR 27191 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation

    Science.gov (United States)

    2010-05-14

    ... AGENCY 40 CFR Parts 51 and 52 RIN 2060-AP80 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... period on our proposed reconsideration of the Prevention of Significant Deterioration (PSD) and...

  5. Topographical map series in the Map Room of Institute and Museum of Military History in Budapest, Hungary between 1919-1945: Smaller scale series (1:100,000, 1:200,000, 1:300,000, 1:500,000, 1:750,000) of the territory of Central Europe

    Science.gov (United States)

    Jankó, A.; Bánfi, R.

    2009-04-01

    The Royal Hungarian State Mapping Institute kept the smaller scales series of the third military survey of the Austro-Hungarian Monarchy, too, so the scales 1:200,000 and 1:750,000 maps. The results of the supervisions of larger scales were transferred onto these scales, 1:200,000 and 1:750,000 maps, for the territory of Central Europe. In 1943 a scale 1:500,000 aerial map was accomplished, too, for the territory of Pannonian basin. There are many other important series in the Map Room between 1919 and 1945, including the WWII German edition 1:300,000 scale map series of Central Europe and Russia to the Ural Mts.; and a series of scale 1:100,000 for the territory of Poland and Russia between 1939-1940.

  6. Thermodynamics of TMPC/PSd/Fullerene Nanocomposites: SANS Study

    KAUST Repository

    Chua, Yang-Choo

    2010-11-23

    Wereport a small angle neutron scattering study of the thermodynamics of a polymer mixture in the presence of nanoparticles, both in equilibrium and during phase separation. Neutron cloud point measurements and random phase approximation (RPA) analysis demonstrate that 1-2 mass % of C60 fullerenes destabilizes a highly interacting mixture of poly(tetramethyl bisphenol A polycarbonate) and deuterated polystyrene (TMPC/PSd). We unequivocally corroborate these findings with time-resolved temperature jump experiments that, in identical conditions, result in phase separation for the nanocomposite and stability for the neat polymer mixture. At lower C 60 loadings (viz. 0.2-0.5 mass %), stabilization of the mixture is observed. The nonmonotonic variation of the spinodal temperature with fullerene addition suggests a competitive interplay of asymmetric component interactions and nanoparticle dispersion. The stability line shift depends critically on particle dispersion and vanishes upon nanoparticle agglomeration. © 2010 American Chemical Society.

  7. Final PSD Permit Extension Letter - Energy Answers Arecibo, LLC/Energy Answers Arecibo Puerto Rico Renewable Energy Project, PR

    Science.gov (United States)

    This page contains the Final PSD Permit Extension Letter for Energy Answers Arecibo Puerto Rico Renewable Energy Project, issued on April 10, 2017 and the EPA Public Announcement for Final PSD Permit Extension for Energy Answers Arecibo, PR.

  8. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

    DEFF Research Database (Denmark)

    Zheng, Sika; Gray, Erin E; Chawla, Geetanjali

    2012-01-01

    Postsynaptic density protein 95 (PSD-95) is essential for synaptic maturation and plasticity. Although its synaptic regulation has been widely studied, the control of PSD-95 cellular expression is not understood. We found that Psd-95 was controlled post-transcriptionally during neural development...

  9. Recovery Room

    African Journals Online (AJOL)

    Before 1950's, patients were usually cared for in an ill-defined postoperative unit or on the hospital ward. Patients were frequently transferred from the operating room directly to the ward where they were placed close to the nursing station. In 1947 the. Anesthesia Study Commission of the Philadelphia. Country Medical ...

  10. Recovery Room

    African Journals Online (AJOL)

    Medical Journal of Zambia, Volume 36 Number 3 (2009). 132. Department of Anaesthesia, University Teaching Hospital ... nursing shortage, stimulated widespread development of recovery rooms. This article summarizes .... Singapore Med J.1997; 38(5): 200-204. 11. Feeley TW, Macario A. Chapter 71: The postanesthesia ...

  11. Maximum Likelihood PSD Estimation for Speech Enhancement in Reverberation and Noise

    DEFF Research Database (Denmark)

    Kuklasinski, Adam; Doclo, Simon; Jensen, Søren Holdt

    2016-01-01

    In this contribution we focus on the problem of power spectral density (PSD) estimation from multiple microphone signals in reverberant and noisy environments. The PSD estimation method proposed in this paper is based on the maximum likelihood (ML) methodology. In particular, we derive a novel ML...... instrumental measures and is shown to be higher than when the competing estimator is used. Moreover, we perform a speech intelligibility test where we demonstrate that both the proposed and the competing PSD estimators lead to similar intelligibility improvements....

  12. POWER SPECTRUM DENSITY (PSD ANALYSIS OF AUTOMOTIVE PEDAL-PAD

    Directory of Open Access Journals (Sweden)

    AHMED RITHAUDDEEN YUSOFF

    2016-04-01

    Full Text Available Vibration at the pedal-pad may contribute to discomfort of foot plantar fascia during driving. This is due to transmission of vibration to the mount, chassis, pedal, and then to the foot plantar fascia. This experimental study is conducted to determine the estimation of peak value using the power spectral density of the vertical vibration input at the foot. The power spectral density value is calculated based on the frequency range between 13 Hz to 18 Hz. This experiment was conducted using 12 subjects testing on three size of pedal-pads; small, medium and large. The result shows that peak value occurs at resonance frequency of 15 Hz. The PSD values at that resonance frequency are 0.251 (m/s2 2/Hz for small pedal-pad, followed by the medium pedal-pad is at 0.387 (m/s2 2/Hz and lastly for the large pedal-pad is at 0.483 (m/s22/Hz. The resultsindicate that during driving, the foot vibration when interact with the large pedal-pad contributed higher stimulus compared with the small and medium pedal-pad. The pedal-pad size plays an important role in the pedal element designs in terms of vibration-transfer from pedal-pads on the feet, particularly to provide comfort to the driver while driving.

  13. Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

    DEFF Research Database (Denmark)

    Fiorentini, Monica; Bach, Anders; Strømgaard, Kristian

    2013-01-01

    the extreme C-terminus of GluD2 with PSD-93 PDZ1 have been investigated in the crystalline phase. Two different binding modes of these residues were observed, suggesting that the peptide is not tightly bound to PSD-93 PDZ1. In accordance, the two N-terminal PSD-93 PDZ domains show no appreciable binding...... affinity for a GluD2-derived C-terminal octapeptide, whereas micromolar affinity was observed for a GluN2B-derived C-terminal octapeptide. This indicates that if present, the interactions between GluD2 and PSD-93 involve more than the extreme terminus of the receptor. In contrast, the tumour...

  14. Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

    Directory of Open Access Journals (Sweden)

    Esperanza Fernández

    2017-10-01

    Full Text Available Arc is an activity-regulated neuronal protein, but little is known about its interactions, assembly into multiprotein complexes, and role in human disease and cognition. We applied an integrated proteomic and genetic strategy by targeting a tandem affinity purification (TAP tag and Venus fluorescent protein into the endogenous Arc gene in mice. This allowed biochemical and proteomic characterization of native complexes in wild-type and knockout mice. We identified many Arc-interacting proteins, of which PSD95 was the most abundant. PSD95 was essential for Arc assembly into 1.5-MDa complexes and activity-dependent recruitment to excitatory synapses. Integrating human genetic data with proteomic data showed that Arc-PSD95 complexes are enriched in schizophrenia, intellectual disability, autism, and epilepsy mutations and normal variants in intelligence. We propose that Arc-PSD95 postsynaptic complexes potentially affect human cognitive function.

  15. PSD microscopy: a new technique for adaptive local scanning of microscale objects.

    Science.gov (United States)

    Rahimi, Mehdi; Shen, Yantao

    2017-01-01

    A position-sensitive detector/device (PSD) is a sensor that is capable of tracking the location of a laser beam on its surface. PSDs are used in many scientific instruments and technical applications including but not limited to atomic force microscopy, human eye movement monitoring, mirrors or machine tool alignment, vibration analysis, beam position control and so on. This work intends to propose a new application using the PSD. That is a new microscopy system called scanning PSD microscopy. The working mechanism is about putting an object on the surface of the PSD and fast scanning its area with a laser beam. To achieve a high degree of accuracy and precision, a reliable framework was designed using the PSD. In this work, we first tried to improve the PSD reading and its measurement performance. This was done by minimizing the effects of noise, distortion and other disturbing parameters. After achieving a high degree of confidence, the microscopy system can be implemented based on the improved PSD measurement performance. Later to improve the scanning efficiency, we developed an adaptive local scanning system to scan the whole area of the PSD in a short matter of time. It was validated that our comprehensive and adaptive local scanning method can shorten the scanning time in order of hundreds of times in comparison with the traditional raster scanning without losing any important information about the scanned 2D objects. Methods are also introduced to scan very complicated objects with bifurcations and crossings. By incorporating all these methods, the new microscopy system is capable of scanning very complicated objects in the matter of a few seconds with a resolution that is in order of a few micrometers.

  16. Small RNAs regulate the biocontrol property of fluorescent Pseudomonas strain Psd.

    Science.gov (United States)

    Upadhyay, Anamika; Kochar, Mandira; Upadhyay, Ashutosh; Tripathy, Soumya; Rajam, Manchikatla Venkat; Srivastava, Sheela

    2017-03-01

    The production of biocontrol factors by Pseudomonads is reported to be controlled at the post-transcriptional level by the GacS/GacA signal transduction pathway. This involves RNA-binding translational repressor proteins, RsmA and RsmE, and the small regulatory RNAs (sRNAs) RsmX, RsmY, and RsmZ. While the former represses genes involved in secondary metabolite production, the latter relieves this repression at the end of exponential growth. We have studied the fluorescent Pseudomonas strain Psd, possessing good biocontrol potential, and confirmed the presence of rsmY and rsmZ by PCR amplification. Gene constructs for all the three small RNAs (RsmX, RsmY and RsmZ) carried on broad host-range plasmid, pME6032 were mobilized into strain Psd. Expression analysis of gacA in the recombinant strains over-expressing rsmX (Psd-pME7320), rsmY (Psd-pME6359) and rsmZ (Psd-pME6918) revealed a significant upregulation of the response regulator. Besides, a remarkable down-regulation of rsmA was also reported in all the strains. The variant strains were found to produce comparatively higher levels of phenazines. Indole acetic acid levels were higher to some extent, and strain Psd-pME6918 also showed elevated production of HCN. The tomato seedlings infected with Fusarium oxysporum and Verticillium dahliae in the presence of culture filtrate of the recombinant strains showed better plant protection response in comparison to the wild-type strain Psd. These results suggest that small RNAs are important determinants in regulation of the biocontrol property of strain Psd. Copyright © 2016 Elsevier GmbH. All rights reserved.

  17. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins.

    Science.gov (United States)

    Fortin, Dale A; Tillo, Shane E; Yang, Guang; Rah, Jong-Cheol; Melander, Joshua B; Bai, Suxia; Soler-Cedeño, Omar; Qin, Maozhen; Zemelman, Boris V; Guo, Caiying; Mao, Tianyi; Zhong, Haining

    2014-12-10

    Stoichiometric labeling of endogenous synaptic proteins for high-contrast live-cell imaging in brain tissue remains challenging. Here, we describe a conditional mouse genetic strategy termed endogenous labeling via exon duplication (ENABLED), which can be used to fluorescently label endogenous proteins with near ideal properties in all neurons, a sparse subset of neurons, or specific neuronal subtypes. We used this method to label the postsynaptic density protein PSD-95 with mVenus without overexpression side effects. We demonstrated that mVenus-tagged PSD-95 is functionally equivalent to wild-type PSD-95 and that PSD-95 is present in nearly all dendritic spines in CA1 neurons. Within spines, while PSD-95 exhibited low mobility under basal conditions, its levels could be regulated by chronic changes in neuronal activity. Notably, labeled PSD-95 also allowed us to visualize and unambiguously examine otherwise-unidentifiable excitatory shaft synapses in aspiny neurons, such as parvalbumin-positive interneurons and dopaminergic neurons. Our results demonstrate that the ENABLED strategy provides a valuable new approach to study the dynamics of endogenous synaptic proteins in vivo. Copyright © 2014 the authors 0270-6474/14/3416698-15$15.00/0.

  18. Stabilization of the angiotensin-(1-7) receptor Mas through interaction with PSD95.

    Science.gov (United States)

    Bian, Weihua; Sun, Licui; Yang, Longyan; Li, Ji-Feng; Hu, Jia; Zheng, Shuai; Guo, Ruihan; Feng, Duiping; Ma, Qian; Shi, Xiaocui; Xiong, Ying; Yang, Xiaomei; Song, Ran; Xu, Jianguo; Wang, Songlin; He, Junqi

    2013-08-01

    The functions and signalling mechanisms of the Ang-(1-7) [angiotensin-(1-7)] receptor Mas have been studied extensively. However, less attention has been paid to the intracellular regulation of Mas protein. In the present study, PSD95 (postsynaptic density 95), a novel binding protein of Mas receptor, was identified, and their association was characterized further. Mas specifically interacts with PDZ1-2, but not the PDZ3, domain of PSD95 via Mas-CT (Mas C-terminus), and the last four amino acids [ETVV (Glu-Thr-Val-Val)] of Mas-CT were determined to be essential for this interaction, as shown by GST pull-down, co-immunoprecipitation and confocal co-localization experiments. Gain-of-function and loss-of-function studies indicated that PSD95 enhanced Mas protein expression by increasing the stabilization of the receptor. Mas degradation was robustly inhibited by the proteasome inhibitor MG132 in time- and dose-dependent manners, and the expression of PSD95 impaired Mas ubiquitination, indicating that the PSD95-Mas association inhibits Mas receptor degradation via the ubiquitin-proteasome proteolytic pathway. These findings reveal a novel mechanism of Mas receptor regulation by which its expression is modulated at the post-translational level by ubiquitination, and clarify the role of PSD95, which binds directly to Mas, blocking the ubiquitination and subsequent degradation of the receptor via the ubiquitin-proteasome proteolytic pathway.

  19. Novel Method of Detecting Movement of the Interference Fringes Using One-Dimensional PSD

    Directory of Open Access Journals (Sweden)

    Qi Wang

    2015-06-01

    Full Text Available In this paper, a method of using a one-dimensional position-sensitive detector (PSD by replacing charge-coupled device (CCD to measure the movement of the interference fringes is presented first, and its feasibility is demonstrated through an experimental setup based on the principle of centroid detection. Firstly, the centroid position of the interference fringes in a fiber Mach-Zehnder (M-Z interferometer is solved in theory, showing it has a higher resolution and sensitivity. According to the physical characteristics and principles of PSD, a simulation of the interference fringe’s phase difference in fiber M-Z interferometers and PSD output is carried out. Comparing the simulation results with the relationship between phase differences and centroid positions in fiber M-Z interferometers, the conclusion that the output of interference fringes by PSD is still the centroid position is obtained. Based on massive measurements, the best resolution of the system is achieved with 5.15, 625 μm. Finally, the detection system is evaluated through setup error analysis and an ultra-narrow-band filter structure. The filter structure is configured with a one-dimensional photonic crystal containing positive and negative refraction material, which can eliminate background light in the PSD detection experiment. This detection system has a simple structure, good stability, high precision and easily performs remote measurements, which makes it potentially useful in material small deformation tests, refractivity measurements of optical media and optical wave front detection.

  20. Impairment of TrkB-PSD-95 signaling in Angelman syndrome.

    Directory of Open Access Journals (Sweden)

    Cong Cao

    Full Text Available Angelman syndrome (AS is a neurodevelopment disorder characterized by severe cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, required for the proteasomal degradation of proteins implicated in synaptic plasticity, such as the activity-regulated cytoskeletal-associated protein (Arc/Arg3.1. Mice deficient in maternal Ube3A express elevated levels of Arc in response to synaptic activity, which coincides with severely impaired long-term potentiation (LTP in the hippocampus and deficits in learning behaviors. In this study, we sought to test whether elevated levels of Arc interfere with brain-derived neurotrophic factor (BDNF TrkB receptor signaling, which is known to be essential for both the induction and maintenance of LTP. We report that TrkB signaling in the AS mouse is defective, and show that reduction of Arc expression to control levels rescues the signaling deficits. Moreover, the association of the postsynaptic density protein PSD-95 with TrkB is critical for intact BDNF signaling, and elevated levels of Arc were found to impede PSD-95/TrkB association. In Ube3A deficient mice, the BDNF-induced recruitment of PSD-95, as well as PLCγ and Grb2-associated binder 1 (Gab1 with TrkB receptors was attenuated, resulting in reduced activation of PLCγ-α-calcium/calmodulin-dependent protein kinase II (CaMKII and PI3K-Akt, but leaving the extracellular signal-regulated kinase (Erk pathway intact. A bridged cyclic peptide (CN2097, shown by nuclear magnetic resonance (NMR studies to uniquely bind the PDZ1 domain of PSD-95 with high affinity, decreased the interaction of Arc with PSD-95 to restore BDNF-induced TrkB/PSD-95 complex formation, signaling, and facilitate the induction of LTP in AS mice. We propose that the failure of TrkB receptor signaling at synapses in AS is directly linked to elevated levels of Arc associated with PSD-95 and PSD-95

  1. Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95

    DEFF Research Database (Denmark)

    Eildal, Jonas N N; Bach, Anders; Dogan, Jakob

    2015-01-01

    PSD-95 is a scaffolding protein of the MAGUK protein family, and engages in several vital protein-protein interactions in the brain with its PDZ domains. It has been suggested that PSD-95 is composed of two supramodules, one of which is the PDZ1-2 tandem domain. Here we have developed rigidified...

  2. Room to Groove?

    DEFF Research Database (Denmark)

    Seabrooke, Leonard

    . As long as they stay within the parameters of legitimate financial practice to signal institutional isomorphism, the `groove', creditors may well allow borrowers room for change in self-determined ways. This paper maps out the historical and conceptual terrain concerning civilizing ideas about...... the legitimacy of financial practices within global capital markets, and investigates relationships between Western `civilizers' and Emerging Market Economies during the last two periods of financial globalization, the late-nineteenth/ early-twentieth centuries and the late-twentieth century.......The use of a `standard of civilization', a preferred form of socio-political organization, in global capital markets presents both constraints and opportunities for creditors and borrowers. When imposed, civilizing standards may change how a borrower would prefer to conduct their affairs. Creditors...

  3. Design and synthesis of triazole-based peptidomimetics of a PSD-95 PDZ domain inhibitor

    DEFF Research Database (Denmark)

    Bach, Anders; Pedersen, Thomas B.; Strømgaard, Kristian

    2016-01-01

    PSD-95 PDZ domains are biologically important and promising drug targets. Here, we discover a triazole-based peptidomimetic, 10, by ‘click chemistry’. Compound 10 inhibits the PDZ2/GluN2B interaction with affinity similar to tripeptide SAV and better than current small-molecules. Thus, 10...

  4. Maximum likelihood PSD estimation for speech enhancement in reverberant and noisy conditions

    DEFF Research Database (Denmark)

    Kuklasinski, Adam; Doclo, Simon; Jensen, Jesper

    2016-01-01

    estimator. Instrumental performance measures indicate an advantage of the proposed estimator over the competing one. In a speech intelligibility test all algorithms significantly improved the word intelligibility score. While the results suggest a minor advantage of using the proposed PSD estimator...

  5. Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.

    Science.gov (United States)

    Fossati, G; Morini, R; Corradini, I; Antonucci, F; Trepte, P; Edry, E; Sharma, V; Papale, A; Pozzi, D; Defilippi, P; Meier, J C; Brambilla, R; Turco, E; Rosenblum, K; Wanker, E E; Ziv, N E; Menna, E; Matteoli, M

    2015-09-01

    Impairment of synaptic function can lead to neuropsychiatric disorders collectively referred to as synaptopathies. The SNARE protein SNAP-25 is implicated in several brain pathologies and, indeed, brain areas of psychiatric patients often display reduced SNAP-25 expression. It has been recently found that acute downregulation of SNAP-25 in brain slices impairs long-term potentiation; however, the processes through which this occurs are still poorly defined. We show that in vivo acute downregulation of SNAP-25 in CA1 hippocampal region affects spine number. Consistently, hippocampal neurons from SNAP-25 heterozygous mice show reduced densities of dendritic spines and defective PSD-95 dynamics. Finally, we show that, in brain, SNAP-25 is part of a molecular complex including PSD-95 and p140Cap, with p140Cap being capable to bind to both SNAP-25 and PSD-95. These data demonstrate an unexpected role of SNAP-25 in controlling PSD-95 clustering and open the possibility that genetic reductions of the protein levels - as occurring in schizophrenia - may contribute to the pathology through an effect on postsynaptic function and plasticity.

  6. Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence.

    Science.gov (United States)

    Fernández, Esperanza; Collins, Mark O; Frank, René A W; Zhu, Fei; Kopanitsa, Maksym V; Nithianantharajah, Jess; Lemprière, Sarah A; Fricker, David; Elsegood, Kathryn A; McLaughlin, Catherine L; Croning, Mike D R; Mclean, Colin; Armstrong, J Douglas; Hill, W David; Deary, Ian J; Cencelli, Giulia; Bagni, Claudia; Fromer, Menachem; Purcell, Shaun M; Pocklington, Andrew J; Choudhary, Jyoti S; Komiyama, Noboru H; Grant, Seth G N

    2017-10-17

    Arc is an activity-regulated neuronal protein, but little is known about its interactions, assembly into multiprotein complexes, and role in human disease and cognition. We applied an integrated proteomic and genetic strategy by targeting a tandem affinity purification (TAP) tag and Venus fluorescent protein into the endogenous Arc gene in mice. This allowed biochemical and proteomic characterization of native complexes in wild-type and knockout mice. We identified many Arc-interacting proteins, of which PSD95 was the most abundant. PSD95 was essential for Arc assembly into 1.5-MDa complexes and activity-dependent recruitment to excitatory synapses. Integrating human genetic data with proteomic data showed that Arc-PSD95 complexes are enriched in schizophrenia, intellectual disability, autism, and epilepsy mutations and normal variants in intelligence. We propose that Arc-PSD95 postsynaptic complexes potentially affect human cognitive function. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  7. Design of a large dynamic range readout unit for the PSD detector of DAMPE

    CERN Document Server

    Zhou, Yong; Sun, Zhiyu; Zhang, Yongjie; Fang, Fang; Chen, Junling; Hu, Bitao

    2016-01-01

    A large dynamic range is required by the Plastic Scintillator Detector (PSD) of DArk Matter Paricle Explorer (DAMPE), and a double-dynode readout has been developed. To verify this design, a prototype detector module has been constructed and tested with cosmic rays and heavy ion beams. The results match with the estimation and the readout unit could easily cover the required dynamic range.

  8. 75 FR 28227 - Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation

    Science.gov (United States)

    2010-05-20

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Parts 51 and 52 RIN 2060-AP80 Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NSR): Aggregation Correction Proposed Rule document 2010-11578 was...

  9. What does it mean to be pseudo single domain? Demystifying the PSD state

    Science.gov (United States)

    Lascu, I.; Harrison, R. J.; Einsle, J. F.; Ball, M.

    2016-12-01

    Until recently, non-interacting stable single domain grains were thought to be the sole reliable paleomagnetic recorders. However most natural samples contain so-called "non-ideal" paleomagnetic recorders, which are either interacting single domain particles, or magnetic grains larger than single domain grains, but smaller than proper multi domain grains, which are poor paleomagnetic recorders. The grain size range for these recorders, which for magnetite comprises grains from 100 nm to a few μm in size, is known as the pseudo single domain (PSD) state. Natural samples containing abundant PSD grains have been shown time and again to reliably record thermomagnetic remanent magnetizations that are stable over billions of years. Here we attempt to shed new light on the PSD state by investigating obsidian varieties found at Glass Butte, Oregon, which present the opportunity to study simple cases of magnetic grains encapsulated in volcanic glass. We do this by combining rock magnetism, scanning electron microscopy (SEM) nanotomography, and finite-element micromagnetic modeling. Using rock magnetism we have identified PSD signatures in these samples via their fingerprint in first-order reversal curve (FORC) diagrams. Tomographic reconstructions obtained by stacking SEM images acquired via sequential milling through sample volumes of a few tens of cubic μm reveal the presence of abundant grains that span the PSD grain size interval. These grains have a variety of shapes, from simple ellipsoidal particles, to more complex morphologies attained through the coalescence of neighboring grains during crystallization, to intricate "rolling snowball" morphologies in larger grains that contain appendices formed as a result of particle growth in a dynamic environment as the flowing lava cooled. Micromagnetic modeling of the simplest morphologies reveals that these grains are in single vortex states, with the remanence controlled by irregularities in grain morphology. Coalesced

  10. Plastic Bonded Explosive (PBX) Particle Size Distribution (PSD) Measurements Using an Image Analysis System

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Gregg K. [Univ. of Wyoming, Laramie, WY (United States)

    2003-06-01

    The slurry process for producing plastic bonded explosives (PBX) has been used for many years. However, until recently the mechanisms involved have not been studied quantitatively to determine the effects of the various control variables. Recently, the effects of operating variables on the final product have been studied; however, no attempt was made to measure particle growth during the slurry process. This study applies an image analysis tool to measure particle size distributions (PSDs) during the slurry process to produce PBX 9501, a specific formulation used in nuclear weapons. The observed PBX 9501 slurry behavior leads away from the typical population balance description of agglomeration, that is, a discrete particle-particle coalescence mechanism. The behavior observed in these experiments indicates that the initial state of the system contains a number of smaller particles clustered together. The cluster then coalesces into a large particle as solvent is removed and the slurry continuously mixed. Other small fragments are picked up and a relatively small amount of growth is observed. A mass transfer model adequately describes solvent removal, and an empirical model is developed to describe the growth behavior in terms of measured process variables. The image system is applied to dried molding powders. The PSD measurement results of the PBX 9501 library lots, historic samples set aside as PBX 9501 lots were accepted from the manufacturer, are also discussed and analyzed. A correlation analysis was conducted to find relationships between the measured PSD and other properties such as bulk density and pressed densities. While no significant correlation was found between the measured PSD and averaged bulk densities for the library lots, significant correlations are found between the measured PSD and pressed density. The final part of the study was to scale-up the PSD measurement capability. Since the large-scale processes are not yet operational, this work

  11. Ocean thermal energy conversion power system development. Final design report: PSD-I, Phase II

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-30

    The PSD-I program provides a heat exchanger sytem consisting of an evaporator, condenser and various ancillaries with ammonia used as a working fluid in a closed simulated Rankine cycle. It is to be installed on the Chepachet Research Vessel for test and evaluation of a number of OTEC concepts in a true ocean environment. It is one of several test articles to be tested. Primary design concerns include control of biofouling, corrosion and erosion of aluminum tubes, selection of materials, and the development of a basis for scale-up to large heat exchangers so as to ultimately demonstrate economic feasibility on a commercial scale. The PSD-I test article is devised to verify thermodynamic, environmental, and mechanical performance of basic design concepts. The detailed design, development, fabrication, checklist, delivery, installation support, and operation support for the Test Article Heat Exchangers are described. (WHK)

  12. Simulated power spectral density (PSD) of background electrocorticogram (ECoG).

    Science.gov (United States)

    Freeman, Walter J; Zhai, Jian

    2009-03-01

    The ECoG background activity of cerebral cortex in states of rest and slow wave sleep resembles broadband noise. The power spectral density (PSD) then may often conform to a power-law distribution: a straight line in coordinates of log power vs. log frequency. The exponent, x, of the distribution, 1/f(x), ranges between 2 and 4. These findings are explained with a model of the neural source of the background activity in mutual excitation among pyramidal cells. The dendritic response of a population of interactive excitatory neurons to an impulse input is a rapid exponential rise and a slow exponential decay, which can be fitted with the sum of two exponential terms. When that function is convolved as the kernel with pulses from a Poisson process and summed, the resulting "brown" or "black noise conforms to the ECoG time series and the PSD in rest and sleep. The PSD slope is dependent on the rate of rise. The variation in the observed slope is attributed to variation in the level of the background activity that is homeostatically regulated by the refractory periods of the excitatory neurons. Departures in behavior from rest and sleep to action are accompanied by local peaks in the PSD, which manifest emergent nonrandom structure in the ECoG, and which prevent reliable estimation of the 1/f(x) exponents in active states. We conclude that the resting ECoG truly is low-dimensional noise, and that the resting state is an optimal starting point for defining and measuring both artifactual and physiological structures emergent in the activated ECoG.

  13. Tank Farm WM-182 and WM 183 Heel Slurry Samples PSD Results

    Energy Technology Data Exchange (ETDEWEB)

    Batcheller, Thomas Aquinas

    2000-09-01

    Particle size distribution (PSD) analysis of INTEC Tank Farm WM-182 and WM-183 heel slurry samples were performed using a modified Horiba LA-300 PSD analyzer at the RAL facility. There were two types of testing performed: typical PSD analysis, and setting rate testing. Although the heel slurry samples were obtained from two separate vessels, the particle size distribution results were quite similar. The slurry solids were from approximately a minimum particle size of 0.5 mm to a maximum of 230 mm-with about 90% of the material between 2-to-133 mm, and the cumulative 50% value at approximately 20 mm. This testing also revealed that high frequency sonication with an ultrasonic element may break-up larger particles in the WM-182 and WM-183 tank from heel slurries. This finding represents useful information regarding ultimate tank heel waste processing. Settling rate testing results were also fairly consistent with material from both vessels in that it appears that most of the mass of solids settle to an agglomerated, yet easily redispersed layer at the bottom. A dispersed and suspended material remained in the "clear" layer above the settled layer after about one-half an hour of settling time. This material had a statistical mode of approximately 5 mm and a maximum particle size of 30 mm.

  14. PSD95 gene specific siRNAs attenuate neuropathic pain through modulating neuron sensibility and postsynaptic CaMKIIα phosphorylation.

    Science.gov (United States)

    Le, Shen; Xu, Li; Wen, Chen; Li, Xu; Wei, Liu; Xue-rong, Yu; Yu-guang, Huang

    2011-12-01

    To observe the effects of PSD95 gene specific siRNAs on neuropathic pain relief, neuron viability, and postsynaptic calcium/calmodulin-dependent protein kinase IIα (CaMKIIα) phosphorylation in vitro and in vivo. Gene-specific siRNAs of rat PSD95 were synthesized chemically for transfection. Adult male Sprague-Dawley (SD) rats were randomly divided into 3 groups: naïve group (n=6), sham group (n=6), and sciatic nerve chronic constriction injury (CCI) group (n=24). The CCI group was further divided into 4 groups (n=6 in each group), which were pretreated with normal saline, transfection vehicle, negative control siRNAs, and PSD95 gene specific siRNAs respectively. All the subgroups received corresponding agents intrathecally for 3 days, started one day before the CCI of sciatic nerve. Both mechanical allodynia and thermal hyperalgesia were measured on post-operative day 3 and 7. PSD95 gene silenced NG108-15 cells were further stimulated by glutamate, with the cell viability and the expression/phosphorylation of CaMKIIα measured by MTT cell proliferation assay and Western blot, respectively. The siRNAs decreased PSD95 mRNA level significantly both in vivo and in vitro. Neuropathic pain rats pretreated with PSD95 gene specific siRNAs exhibited significant elevation in the mechanical withdrawal threshold and paw withdrawal thermal latency, without affecting the baseline nociception. PSD95 gene silencing enhanced neuronal tolerance against the glutamate excitotoxicity, meanwhile the phosphorylation of CaMKIIα Thr286 was attenuated. Pre-emptive administration of PSD95 gene specific siRNAs may attenuate the central sensitization CaMKIIα-related signaling cascades, leading to the relief of neuropathic pain.

  15. Comparing the response of PSD-capable plastic scintillator to standard liquid scintillator

    Science.gov (United States)

    Woolf, Richard S.; Hutcheson, Anthony L.; Gwon, Chul; Phlips, Bernard F.; Wulf, Eric A.

    2015-06-01

    This work discusses a test campaign to characterize the response of the recently developed plastic scintillator with pulse shape discrimination (PSD) capabilities (EJ-299-33). PSD is a property exhibited by certain types of scintillating material in which incident stimuli (fast neutrons or γ rays) can be separated by exploiting differences in the scintillation light pulse tail. Detector geometries used were: a 10 cm×10 cm×10 cm cube and a 10-cm diameter×10-cm long cylinder. EJ-301 and EJ-309 liquid scintillators with well-known responses were also tested. The work was conducted at the University of Massachusetts Lowell Van De Graaff accelerator. The facility accelerated protons on a thin Li target to yield quasi-monoenergetic neutrons from the 7Li(p,n)7Be reaction (Q-value: -1.644 MeV). Collimated fast neutrons were obtained by placing detectors behind a neutron spectrometer. Rotating the spectrometer, and thus changing the neutron energy, allowed us to achieve 0.5-3.2 MeV neutrons in 200-300 keV steps. Data were acquired through a flash analog-to-digital converter (ADC) capable of performing digital PSD measurements. By using the PSD technique to separate the neutron events from unwanted γ background, we constructed a pulse height spectrum at each energy. Obtaining a relationship of the relative light output versus energy allowed us to construct the response function for the EJ-299-33 and liquid scintillator. The EJ-299-33 response in terms of electron equivalent energy (Ee.e.) vs. proton equivalent energy (Ep.e.), how it compared with the standard xylene-based EJ-301 (or, NE-213/BC-501 A equivalent) and EJ-309 liquid scintillator response, and how the EJ-301 and EJ-309 compared, are presented. We find that the EJ-299-33 demonstrated a lower light output by up to 40% for environment affected the detector response. We find relatively good agreement between our results and the modeling; however, the observed response could not be fully accounted for due to

  16. Human-Like Room Segmentation for Domestic Cleaning Robots

    Directory of Open Access Journals (Sweden)

    David Fleer

    2017-11-01

    Full Text Available Autonomous mobile robots have recently become a popular solution for automating cleaning tasks. In one application, the robot cleans a floor space by traversing and covering it completely. While fulfilling its task, such a robot may create a map of its surroundings. For domestic indoor environments, these maps often consist of rooms connected by passageways. Segmenting the map into these rooms has several uses, such as hierarchical planning of cleaning runs by the robot, or the definition of cleaning plans by the user. Especially in the latter application, the robot-generated room segmentation should match the human understanding of rooms. Here, we present a novel method that solves this problem for the graph of a topo-metric map: first, a classifier identifies those graph edges that cross a border between rooms. This classifier utilizes data from multiple robot sensors, such as obstacle measurements and camera images. Next, we attempt to segment the map at these room–border edges using graph clustering. By training the classifier on user-annotated data, this produces a human-like room segmentation. We optimize and test our method on numerous realistic maps generated by our cleaning-robot prototype and its simulated version. Overall, we find that our method produces more human-like room segmentations compared to mere graph clustering. However, unusual room borders that differ from the training data remain a challenge.

  17. PSD Applicability Determination for Power Boiler No. 4 at the Potlatch Corporation Facility in Lewiston, Idaho

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  18. Simpson Pulp and Paper Mill in Tacoma, Washington, PSD applicability determination for Power Boiler No. 7

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  19. Applicability of the PSD Regulations to Certain Modifications Made by Cooper Tire and Rubber Company

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  20. Tire Derived Fuel Classified as Municipal Solid Waste for a PSD Exemption

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  1. Contingency Plan for FGD Systems During Downtime as a Function of PSD

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  2. Automatic or Blanket Exemptions for Excess Emissions During Startup, and Shutdowns Under PSD

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  3. PSD Applicability Determination for AEG Bovoni Power's Waste-to-Energy Project

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  4. PSD and NSPS Applicability Determination for Guardian Industries' Flat Glass Plant in Corsicana, Texas

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  5. Clarification That BACT Analysis Under PSD is Applicable for A Proposed Modification to the Rotary Kiln

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  6. PSD Analysis for SIP Relaxation in Metropolitan Boston Air Pollution Control District - Eastman Gelatin

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  7. Applicablitiy Determinations on the PSD 100 tpy Major Source Threshold Catergory for Fossil Fuel Boilers Industries

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  8. Inclusion of Haul Road Emissions in PSD Applicability Determination for Coal Mine and Preparation Plant

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  9. Applicability of PSD and NSPS to the Cleveland Electric, Incorporated, Plant in Willoughby, Ohio

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  10. NSR Advisory Memo # 1 : TSP PSD Increment Consumption in North Carolina

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  11. Our Urban Living Room

    DEFF Research Database (Denmark)

    Hjortshøj, Rasmus

    2016-01-01

    Our Urban Living Room is an exhibition and a book, created by Cobe. The theme is based on Cobe’s ten years of practice, grounded in social livability and urban democracy, and our aim to create buildings and spaces that invite Copenhageners to use and define them; as an extended living room, where...... the boundaries between private and public space become fluid. Based on specific Cobe projects, Our Urban Living Room tells stories about the architectural development of Copenhagen, while exploring the progression of the Danish Capital - from an industrial city into an urban living room, known as one...

  12. Health Physics counting room

    CERN Multimedia

    CERN PhotoLab

    1970-01-01

    The Health Physics counting room, where the quantity of induced radioactivity in materials is determined. This information is used to evaluate possible radiation hazards from the material investigated.

  13. Simulated and Real Sheet-of-Light 3D Object Scanning Using a-Si:H Thin Film PSD Arrays

    Directory of Open Access Journals (Sweden)

    Javier Contreras

    2015-11-01

    Full Text Available A MATLAB/SIMULINK software simulation model (structure and component blocks has been constructed in order to view and analyze the potential of the PSD (Position Sensitive Detector array concept technology before it is further expanded or developed. This simulation allows changing most of its parameters, such as the number of elements in the PSD array, the direction of vision, the viewing/scanning angle, the object rotation, translation, sample/scan/simulation time, etc. In addition, results show for the first time the possibility of scanning an object in 3D when using an a-Si:H thin film 128 PSD array sensor and hardware/software system. Moreover, this sensor technology is able to perform these scans and render 3D objects at high speeds and high resolutions when using a sheet-of-light laser within a triangulation platform. As shown by the simulation, a substantial enhancement in 3D object profile image quality and realism can be achieved by increasing the number of elements of the PSD array sensor as well as by achieving an optimal position response from the sensor since clearly the definition of the 3D object profile depends on the correct and accurate position response of each detector as well as on the size of the PSD array.

  14. Fuzzy norm method for evaluating random vibration of airborne platform from limited PSD data

    Directory of Open Access Journals (Sweden)

    Wang Zhongyu

    2014-12-01

    Full Text Available For random vibration of airborne platform, the accurate evaluation is a key indicator to ensure normal operation of airborne equipment in flight. However, only limited power spectral density (PSD data can be obtained at the stage of flight test. Thus, those conventional evaluation methods cannot be employed when the distribution characteristics and priori information are unknown. In this paper, the fuzzy norm method (FNM is proposed which combines the advantages of fuzzy theory and norm theory. The proposed method can deeply dig system information from limited data, which probability distribution is not taken into account. Firstly, the FNM is employed to evaluate variable interval and expanded uncertainty from limited PSD data, and the performance of FNM is demonstrated by confidence level, reliability and computing accuracy of expanded uncertainty. In addition, the optimal fuzzy parameters are discussed to meet the requirements of aviation standards and metrological practice. Finally, computer simulation is used to prove the adaptability of FNM. Compared with statistical methods, FNM has superiority for evaluating expanded uncertainty from limited data. The results show that the reliability of calculation and evaluation is superior to 95%.

  15. Virtual Seminar Room

    DEFF Research Database (Denmark)

    Forchhammer, Søren Otto; Fosgerau, Anders; Hansen, Peter Søren Kirk

    1999-01-01

    The initial design considerations and research goals for an ATM network based virtual seminar room with 5 sites are presented.......The initial design considerations and research goals for an ATM network based virtual seminar room with 5 sites are presented....

  16. Operating room manager game

    NARCIS (Netherlands)

    Hans, Elias W.; Nieberg, T.

    2007-01-01

    The operating room (OR) department of a hospital forms the heart of the organization, where the single largest cost is incurred. This document presents and reports on the “Operating Room Manager Game,” developed to give insight into managing a large hospital's OR department at various levels of

  17. Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95.

    Science.gov (United States)

    Daut, Rachel A; Busch, Erica F; Ihne, Jessica; Fisher, Daniel; Mishina, Masayoshi; Grant, Seth G N; Camp, Marguerite; Holmes, Andrew

    2015-03-01

    The neural and genetic factors underlying chronic tolerance to alcohol are currently unclear. The GluN2A N-methyl-D-aspartate receptors (NMDAR) subunit and the NMDAR-anchoring protein PSD-95 mediate acute alcohol intoxication and represent putative mechanisms mediating tolerance. We found that chronic intermittent ethanol exposure (CIE) did not produce tolerance [loss of righting reflex (LORR)] or withdrawal-anxiety in C57BL/6J, GluN2A or PSD-95 knockout mice assayed 2-3 days later. However, significant tolerance to LORR was evident 1 day after CIE in C57BL/6J and PSD-95 knockouts, but absent in GluN2A knockouts. These data suggest a role for GluN2A in tolerance, extending evidence that human GluN2A gene variation is involved in alcohol dependence. © 2014 Society for the Study of Addiction.

  18. Effect of complex aerobic physical exercise on PSD-95 in the hippocampus and on cognitive function in juvenile mice

    Science.gov (United States)

    Satriani, W. H.; Redjeki, S.; Kartinah, N. T.

    2017-08-01

    Increased neuroplasticity induced by complex aerobic physical exercise is associated with improved cognitive function in adult mice. Increased cognitive function is assumed to be based on increased synapse formation. One of the regions of the brain that is important in cognitive function is the hippocampus, which plays a role in memory formation. Post synaptic density-95 (PSD-95) is an adhesion protein of the post-synaptic density scaffolding that is essential to synaptic stabilization. As we age, the PSD-95 molecule matures the synapses needed for the formation of the basic circuitry of the nervous system in the brain. However, during the growth period, synapse elimination is higher than its formation. This study aims to determine whether complex aerobic exercise can improve cognitive function and PSD-95 levels in the hippocampus of juvenile mice during their growth stage. The mice performed complex aerobic exercise starting at five weeks of age and continuing for seven weeks with a gradual increase of 8 m/min. At eight weeks it was increased to 10 m/min. The exercise was done for five days of each week. The subjects of the study were tested for cognition one week before being sacrificed (at 12 weeks). The PSD-95 in the hippocampus was measured with ELISA. The results showed that there was a significant difference in cognitive function, where p exercise and a control group that did not. However, the PSD-95 levels did not differ significantly between the two groups. The results of this study indicate that early complex aerobic exercise can improve cognitive ability in adulthood but does not increase the levels of PSD-95 in adults.

  19. Binaural noise reduction via cue-preserving MMSE filter and adaptive-blocking-based noise PSD estimation

    Science.gov (United States)

    Azarpour, Masoumeh; Enzner, Gerald

    2017-12-01

    Binaural noise reduction, with applications for instance in hearing aids, has been a very significant challenge. This task relates to the optimal utilization of the available microphone signals for the estimation of the ambient noise characteristics and for the optimal filtering algorithm to separate the desired speech from the noise. The additional requirements of low computational complexity and low latency further complicate the design. A particular challenge results from the desired reconstruction of binaural speech input with spatial cue preservation. The latter essentially diminishes the utility of multiple-input/single-output filter-and-sum techniques such as beamforming. In this paper, we propose a comprehensive and effective signal processing configuration with which most of the aforementioned criteria can be met suitably. This relates especially to the requirement of efficient online adaptive processing for noise estimation and optimal filtering while preserving the binaural cues. Regarding noise estimation, we consider three different architectures: interaural (ITF), cross-relation (CR), and principal-component (PCA) target blocking. An objective comparison with two other noise PSD estimation algorithms demonstrates the superiority of the blocking-based noise estimators, especially the CR-based and ITF-based blocking architectures. Moreover, we present a new noise reduction filter based on minimum mean-square error (MMSE), which belongs to the class of common gain filters, hence being rigorous in terms of spatial cue preservation but also efficient and competitive for the acoustic noise reduction task. A formal real-time subjective listening test procedure is also developed in this paper. The proposed listening test enables a real-time assessment of the proposed computationally efficient noise reduction algorithms in a realistic acoustic environment, e.g., considering time-varying room impulse responses and the Lombard effect. The listening test outcome

  20. PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarisation in cortical spreading depression

    DEFF Research Database (Denmark)

    Kucharz, Krzysztof; Søndergaard Rasmussen, Ida; Bach, Anders

    2017-01-01

    , UCCB01-144 (Tat-N-dimer) ameliorates the persistent effects of cortical spreading depression on cortical function. Using in vivo two-photon microscopy in somatosensory cortex in mice, we show that fluorescently labelled Tat-N-dimer readily crosses blood-brain barrier and accumulates in nerve cells...... depression on cortical blood flow and CMRO2 We suggest that uncoupling of PSD-95 from NMDA receptors reduces overall neuronal excitability and the amplitude of the spreading depolarisation wave. These findings may be of interest for understanding the neuroprotective effects of the nNOS/PSD-95 uncoupling...

  1. Single-Molecule Imaging of PSD-95 mRNA Translation in Dendrites and Its Dysregulation in a Mouse Model of Fragile X Syndrome.

    Science.gov (United States)

    Ifrim, Marius F; Williams, Kathryn R; Bassell, Gary J

    2015-05-06

    Fragile X syndrome (FXS) is caused by the loss of the fragile X mental retardation protein (FMRP), an RNA binding protein that regulates translation of numerous target mRNAs, some of which are dendritically localized. Our previous biochemical studies using synaptoneurosomes demonstrate a role for FMRP and miR-125a in regulating the translation of PSD-95 mRNA. However, the local translation of PSD-95 mRNA within dendrites and spines, as well as the roles of FMRP or miR-125a, have not been directly studied. Herein, local synthesis of a Venus-PSD-95 fusion protein was directly visualized in dendrites and spines using single-molecule imaging of a diffusion-restricted Venus-PSD-95 reporter under control of the PSD-95 3'UTR. The basal translation rates of Venus-PSD-95 mRNA was increased in cultured hippocampal neurons from Fmr1 KO mice compared with WT neurons, which correlated with a transient elevation of endogenous PSD-95 within dendrites. Following mGluR stimulation with (S)-3,5-dihydroxyphenylglycine, the rate of Venus-PSD-95 mRNA translation increased rapidly in dendrites of WT hippocampal neurons, but not in those of Fmr1 KO neurons or when the binding site of miR125a, previously shown to bind PSD-95 3'UTR, was mutated. This study provides direct support for the hypothesis that local translation within dendrites and spines is dysregulated in FXS. Impairments in the regulated local synthesis of PSD-95, a critical regulator of synaptic structure and function, may affect the spatiotemporal control of PSD-95 levels and affect dendritic spine development and synaptic plasticity in FXS. Copyright © 2015 the authors 0270-6474/15/357116-15$15.00/0.

  2. The Virtual Dressing Room

    DEFF Research Database (Denmark)

    Holte, Michael Boelstoft; Gao, Yi; Petersson, Eva

    2015-01-01

    This paper presents the design and evaluation of a usability and user experience test of a virtual dressing room. First, we motivate and introduce our recent developed prototype of a virtual dressing room. Next, we present the research and test design grounded in related usability and user...... experience studies. We give a description of the experimental setup and the execution of the designed usability and user experience test. To this end, we report interesting results and discuss the results with respect to user-centered design and development of a virtual dressing room....

  3. RILIS laser room HD

    CERN Multimedia

    2016-01-01

    Footage of the RILIS laser room at ISOLDE. The Resonance Ionization Laser Ion Source (RILIS) is a chemically selective ion source which relies on resonant excitation of atomic transitions using tunable laser radiation. This video shows you the laser table with the different lenses and optics as well as an overview of the RILIS laser setup. It also shows laser light with different colors and operation by the RILIS laser experts. The last part of the video shows you the laser path from the RILIS laser room into the ISOLDE GPS separator room where it enters the GPS separator magnet.

  4. RILIS laser room

    CERN Multimedia

    2016-01-01

    Footage of the RILIS laser room at ISOLDE. The Resonance Ionization Laser Ion Source (RILIS) is a chemically selective ion source which relies on resonant excitation of atomic transitions using tunable laser radiation. This video shows you the laser table with the different lenses and optics as well as an overview of the RILIS laser setup. It also shows laser light with different colors and operation by the RILIS laser experts. The last part of the video shows you the laser path from the RILIS laser room into the ISOLDE GPS separator room where it enters the GPS separator magnet.

  5. Room for caring

    DEFF Research Database (Denmark)

    Timmermann, Connie; Uhrenfeldt, Lisbeth; Birkelund, Regner

    2015-01-01

    rooms such as a view of nature or natural light entering the room are often neglected in caring for these patients. Method A phenomenological-hermeneutic study design was applied and data was collected through multiple qualitative interviews combined with observations at a teaching hospital in Denmark......) Experiencing inner peace and an escape from negative thoughts, (ii) Experiencing a positive mood and hope and (iii) Experiencing good memories. Conclusion Our findings highlight aesthetic sensory impressions in the form of nature sights and natural light in the patient room as a powerful source of well...

  6. Predicting Acoustics in Class Rooms

    DEFF Research Database (Denmark)

    Christensen, Claus Lynge; Rindel, Jens Holger

    2005-01-01

    Typical class rooms have fairly simple geometries, even so room acoustics in this type of room is difficult to predict using today's room acoustic computer modeling software. The reasons why acoustics of class rooms are harder to predict than acoustics of complicated concert halls might...

  7. PSD Camera Based Position and Posture Control of Redundant Robot Considering Contact Motion

    Science.gov (United States)

    Oda, Naoki; Kotani, Kentaro

    The paper describes a position and posture controller design based on the absolute position by external PSD vision sensor for redundant robot manipulator. The redundancy enables a potential capability to avoid obstacle while continuing given end-effector jobs under contact with middle link of manipulator. Under contact motion, the deformation due to joint torsion obtained by comparing internal and external position sensor, is actively suppressed by internal/external position hybrid controller. The selection matrix of hybrid loop is given by the function of the deformation. And the detected deformation is also utilized in the compliant motion controller for passive obstacle avoidance. The validity of the proposed method is verified by several experimental results of 3link planar redundant manipulator.

  8. UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801

    DEFF Research Database (Denmark)

    Andreasen, Jesper T.; Bach, Anders; Gynther, Mikko

    2013-01-01

    Excessive N-Methyl-d-aspartate receptor (NMDAR)-dependent production of nitric oxide (NO) is involved in the development and maintenance of chronic pain states, and is mediated by postsynaptic density protein-95 (PSD-95). By binding to both the NMDAR and neuronal NO synthase (nNOS), PSD-95 mediates...... the NMDAR/PSD-95/nNOS complex by targeting PSD-95, thereby decreasing NO production without interfering with the NMDAR ion channel function. Here, we compared the effects of a dimeric PSD-95 inhibitor, UCCB01-125, and the NMDAR antagonist, MK-801, on mechanical hypersensitivity in the complete Freund......-induced mechanical hypersensitivity 1 and 24 h after treatment. Moreover, UCCB01-125 was found to reverse CFA-induced hypersensitivity when administered 24 h after CFA treatment, an effect lasting for at least 3 days. At the dose reducing hypersensitivity, MK-801 disrupted attention, long-term memory, and motor...

  9. Operating Room Telephone Microbial Flora

    National Research Council Canada - National Science Library

    Nelson, Jason; Shinn, Antoinette M; Bivens, Ava

    2005-01-01

    ...) could be found on telephones in the Operating Room (OR). A total of 26 cultures were taken from telephones within 14 operating rooms and two sub-sterile rooms at a large, teaching, medical center...

  10. Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function

    DEFF Research Database (Denmark)

    Andreasen, Jesper T; Nasser, Arafat; Caballero-Puntiverio, Maitane

    2016-01-01

    NMDAR antagonism shows analgesic action in humans and animal pain models, but disrupts cognitive and motor functions. NMDAR-dependent NO production requires tethering of the NMDAR to neuronal NO synthase (nNOS) by the postsynaptic density protein-95 (PSD-95). Perturbing the NMDAR/PSD-95/nNOS inte...... in the STFP test. Collectively, UCCB01-144 reversed both CFA and SNI-induced hypersensitivity, but the efficacy in the SNI model was only transient. This suggests that enhanced BBB permeability of PSD-95 inhibitors improves the analgesic action in neuropathic pain states.......NOS interaction has therefore been proposed as an alternative analgesic mechanism. We recently reported that UCCB01-125, a dimeric PSD-95 inhibitor with limited blood-brain-barrier permeability, reduced mechanical hypersensitivity in the complete Freund's adjuvant (CFA) inflammatory pain model, without disrupting...... of neuropathic pain. Potential cognitive effects of UCCB01-144 were examined using the social transmission of food preference (STFP) test and the V-maze test, and motor coordination was assessed with the rotarod test. UCCB01-144 (10mg/kg) reversed CFA-induced mechanical hypersensitivity after 1h, and completely...

  11. ALICE’s new meeting room

    CERN Multimedia

    2009-01-01

    There’s no reason to be late for a meeting in Wonderland (Point 2) anymore as ALICE gets a brand new conference room and a ‘clean up’. The new ALICE conference room.You won’t find Building 3294 on the CERN map yet, but it is already being used. If you follow the white rabbit just inside the entrance at point 2, you will find a new conference room and office space for 12 people. "Previously at Point 2 we’ve had very little office space at all. Our old conference room was inside the main building, SX2, but it was cramped and extremely noisy," explained Frank Cliff from ALICE. "As soon as they turned on the overhead cranes you could barely hear yourself think!" The plans for the new building were drawn up by the Civil Engineering Group, and construction started in August last year. The building was completed and already in use before Christmas. The 109 square metre conference room can fit up to 60 people and is fully equipped...

  12. Simulations of a PSD Plastic Neutron Collar for Assaying Fresh Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Hausladen, Paul [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Newby, Jason [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); McElroy, Robert Dennis [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-11-01

    The potential performance of a notional active coincidence collar for assaying uranium fuel based on segmented detectors constructed from the new PSD plastic fast organic scintillator with pulse shape discrimination capability was investigated in simulation. Like the International Atomic Energy Agency's present Uranium Neutron Collar for LEU (UNCL), the PSD plastic collar would also function by stimulating fission in the 235U content of the fuel with a moderated 241Am/Li neutron source and detecting instances of induced fission via neutron coincidence counting. In contrast to the moderated detectors of the UNCL, the fast time scale of detection in the scintillator eliminates statistical errors due to accidental coincidences that limit the performance of the UNCL. However, the potential to detect a single neutron multiple times historically has been one of the properties of organic scintillator detectors that has prevented their adoption for international safeguards applications. Consequently, as part of the analysis of simulated data, a method was developed by which true neutron-neutron coincidences can be distinguished from inter-detector scatter that takes advantage of the position and timing resolution of segmented detectors. Then, the performance of the notional simulated coincidence collar was evaluated for assaying a variety of fresh fuels, including some containing burnable poisons and partial defects. In these simulations, particular attention was paid to the analysis of fast mode measurements. In fast mode, a Cd liner is placed inside the collar to shield the fuel from the interrogating source and detector moderators, thereby eliminating the thermal neutron flux that is most sensitive to the presence of burnable poisons that are ubiquitous in modern nuclear fuels. The simulations indicate that the predicted precision of fast mode measurements is similar to what can be achieved by the present UNCL in thermal mode. For example, the

  13. Double-tract reconstruction after laparoscopic proximal gastrectomy using detachable ENDO-PSD.

    Science.gov (United States)

    Aburatani, Tomoki; Kojima, Kazuyuki; Otsuki, Sho; Murase, Hideaki; Okuno, Keisuke; Gokita, Kentaro; Tomii, Chiharu; Tanioka, Toshiro; Inokuchi, Mikito

    2017-04-07

    Proximal gastrectomy (PG) is widely performed in Japan as a function-preserving surgical approach. Since esophagogastrostomy (EG) was associated with increased reflux symptoms and anastomotic strictures, we have chosen double-tract reconstruction (DTR) as the standard reconstruction method since March 2013. In this study, we described a novel method of laparoscopic DTR using detachable ENDO-PSD and compared its 1-year outcome with EG performed formerly in our institution. Patients who underwent laparoscopic PG between May 2005 and July 2014 were retrospectively divided into two groups based on the type of reconstruction and were subsequently analyzed (19 patients in the DTR group and 22 in the EG group). All of them underwent a laparoscopic PG with regional lymph node dissection. In the DTR group, the lower left port site was extended to 4 cm, and an intracorporeal purse-string suture was performed using the detachable ENDO-PSD. The jejunogastrostomy was fashioned on the anterior side of the remnant stomach parallel to the transection line, 2 cm from the cut end. The EG group used the conventional purse-string suture instrument through the 6 cm upper midline mini-laparotomy incision. Patient characteristics, operative data, early operative complications and 1-year postoperative follow-up findings were compared between the two groups. The frequencies of reflux symptoms (10.5 vs. 54.5%, P = 0.003), usage of proton pump inhibitors (31.6 vs. 72.7%, P = 0.008), and anastomotic strictures (0 vs. 27%, P = 0.014) were significantly lower in the DTR group as compared to the EG group. There were no significant differences between the two groups with regard to operation time, blood loss, postoperative hospital stay, postoperative complications, average postoperative/preoperative weight loss ratio, and postoperative/preoperative ratio of biochemical markers (hemoglobin, total protein, albumin, cholesterol). Our results indicate that DTR is a useful reconstruction

  14. Digital Operating Room assistant

    NARCIS (Netherlands)

    Geudon, A.C.P.

    2016-01-01

    The Operating Room (OR) is a complex environment, where a large variety of patients and diseases can be treated and many unexpected events occur (such as emergency surgeries and unexpected progress of procedures). In practice, OR assistants support OR processes as well as they can, in order to

  15. Rooms with a View

    Science.gov (United States)

    Hourihan, Peter; Berry, Millard, III

    2006-01-01

    When well-designed and integrated into a campus living or learning space, an atrium can function as the heart and spirit of a building, connecting interior rooms and public spaces with the outside environment. However, schools and universities should seek technological and HVAC solutions that maximize energy efficiency. This article discusses how…

  16. Operating room rescheduling

    NARCIS (Netherlands)

    van Essen, J. Theresia; Hurink, Johann L.; Hartholt, W.; van den Akker, B.J.

    2012-01-01

    Due to surgery duration variability and arrivals of emergency surgeries, the planned Operating Room (OR) schedule is disrupted throughout the day which may lead to a change in the start time of the elective surgeries. These changes may result in undesirable situations for patients, wards or other

  17. The Virtual Dressing Room

    DEFF Research Database (Denmark)

    Holte, Michael Boelstoft

    2013-01-01

    This paper presents a review of recent developments and future perspectives, addressing the problem of creating a virtual dressing room. First, we review the current state-of-the-art of exiting solutions and discuss their applicability and limitations. We categorize the exiting solutions into thr...

  18. Parametric Room Acoustic Workflows

    DEFF Research Database (Denmark)

    Parigi, Dario; Svidt, Kjeld; Molin, Erik

    2017-01-01

    The paper investigates and assesses different room acoustics software and the opportunities they offer to engage in parametric acoustics workflow and to influence architectural designs. The first step consists in the testing and benchmarking of different tools on the basis of accuracy, speed...

  19. PS Control Room

    CERN Multimedia

    CERN PhotoLab

    1963-01-01

    The good old PS Control Room, all manual. For each parameter, a knob or a button to control it; for each, a light or meter or oscilloscope to monitor it; carefully written pages serve as the data bank; phones and intercom for communication. D.Dekkers is at the microphone, M.Valvini sits in front.

  20. Birth room images

    DEFF Research Database (Denmark)

    Bowden, Calida; Sheehan, Athena; Foureur, Maralyn Jean

    2016-01-01

    Objective: this study examined images of birth rooms in developed countries to analyse the messages and visual discourse being communicated through images. Design: a small qualitative study using Kress and van Leeuwen's (2006) social semiotic theoretical framework for image analysis, a form of di...

  1. Players over the Surface: Unraveling the Role of Exopolysaccharides in Zinc Biosorption by Fluorescent Pseudomonas Strain Psd.

    Science.gov (United States)

    Upadhyay, Anamika; Kochar, Mandira; Rajam, Manchikatla V; Srivastava, Sheela

    2017-01-01

    Fluorescent Pseudomonas strain Psd is a soil isolate, possessing multiple plant growth promoting (PGP) properties and biocontrol potential. In addition, the strain also possesses high Zn2+ biosorption capability. In this study, we have investigated the role exopolysaccharides (EPS) play in Zn2+ biosorption. We have identified that alginates are the prime components contributing to Zn2+ biosorption. Deletion of the alg8 gene, which codes for a sub-unit of alginate polymerase, led to a significant reduction in EPS production by the organism. We have also demonstrated that the increased alginate production in response to Zn2+ exposure leads to improved biofilm formation by the strain. In the alg8 deletion mutant, however, biofilm formation was severely compromised. Further, we have studied the functional implications of Zn2+ biosorption by Pseudomonas strain Psd by demonstrating the effect on the PGP and biocontrol potential of the strain.

  2. Air Distribution in Rooms

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    The research on air distribution in rooms is often done as full-size investigations, scale-model investigations or by Computational Fluid Dynamics (CFD). New activities have taken place within all three areas and this paper draws comparisons between the different methods. The outcome of the l......EA sponsored research "Air Flow Pattern within Buildings" is used for comparisons in some parts of the paper because various types of experiments and many countries are involved....

  3. [Virtual room of gastroenterology].

    Science.gov (United States)

    Spinelli, Osvaldo Mateo; Fittipaldi, Mónica Elsa; Henderson, Eduardo; Krabshuis, Justus Hendrik

    2010-12-01

    The amount of published information and its continuing growth can no longer be managed by an individual searcher. One of today's great challenges for the academic researcher and clinician is to find a relevant scientific article using bibliographic search strategies. We aimed to design and build a Virtual Room of Gastroenterology (VRG) generating real-time automated search strategies and producing bibliographic and full text search results. These results update and complement with the latest evidence the Clinical Guideline Program of the World Gastroenterology Organisation. The HTML driven interface provides a series of pre-formulated MeSH based search strategies for each Aula. For each topic between 10 and 20 specific terms, qualifiers and subheadings are identified. The functionality of the VRG is based on the PubMed's characteristic that allows a search strategy to be captured as a web address. The VRG is available in Spanish and English, and the access is free. There are 28 rooms currently available. All together these rooms provide an advanced bibliographic access using more than 900 pre-programmed MeSH driven strategies. In a further very recent development some of the topics of VRG now allow cascade based searches. These searches look at resource sensitive options and possible ethnic difference per topic. The VRG allows significant reductions in time required to design and carry out complex bibliographic searches in the areas of gastroenterology, hepatology and endoscopy. The system updates automatically in real-time thus ensuring the currency of the results.

  4. Planets in a Room

    Science.gov (United States)

    Giacomini, l.; Aloisi, F.; De Angelis, I.

    2017-09-01

    Teaching planetary science using a spherical projector to show the planets' surfaces is a very effective but usually very expensive idea. Whatsmore, it usually assumes the availability of a dedicated space and a trained user. "Planets in a room" is a prototypal low cost version of a small, spherical projector that teachers, museum, planetary scientists and other individuals can easily build and use on their own, to show and teach the planets The project of "Planets in a Room" was made by the italian non-profit association Speak Science with the collaboration of INAF-IAPS of Rome and the Roma Tre University (Dipartimento di Matematica e Fisica). This proposal was funded by the Europlanet Outreach Funding Scheme in 2016. "Planets in a room" will be presented during EPSC 2017 to give birth to the second phase of the project, when the outreach and research community will be involved and schools from all over Europe will be invited to participate with the aim of bringing planetary science to a larger audience.

  5. G quadruplex RNA structures in PSD-95 mRNA: potential regulators of miR-125a seed binding site accessibility.

    Science.gov (United States)

    Stefanovic, Snezana; Bassell, Gary J; Mihailescu, Mihaela Rita

    2015-01-01

    Fragile X syndrome (FXS) is the most common inherited form of intellectual disability caused by the CGG trinucleotide expansion in the 3'-untranslated region of the FMR1 gene on the X chromosome, that silences the expression of the Fragile X mental retardation protein (FMRP). FMRP has been shown to bind to a G-rich region within the PSD-95 mRNA which encodes for the postsynaptic density protein 95 (PSD-95), and together with the microRNA miR-125a, to play an important role in the reversible inhibition of the PSD-95 mRNA translation in neurons. The loss of FMRP in Fmr1 KO mice disables this translation control in the production of the PSD-95 protein. Interestingly, the miR-125a binding site on PSD-95 mRNA is embedded in the G-rich region bound by FMRP and postulated to adopt one or more G quadruplex structures. In this study, we have used different biophysical techniques to validate and characterize the formation of parallel G quadruplex structures and binding of miR-125a to its complementary sequence located within the 3' UTR of PSD-95 mRNA. Our results indicate that the PSD-95 mRNA G-rich region folds into alternate G quadruplex conformations that coexist in equilibrium. miR-125a forms a stable complex with PSD-95 mRNA, as evident by characteristic Watson-Crick base-pairing that coexists with one of the G quadruplex forms, suggesting a novel mechanism for G quadruplex structures to regulate the access of miR-125a to its binding site. © 2014 Stefanovic et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  6. Beta1-adrenergic receptor-mediated dilation of rat cerebral artery requires Shaker-type KV1 channels on PSD95 scaffold.

    Science.gov (United States)

    Moore, Christopher L; McClenahan, Samantha J; Hanvey, Hillary M; Jang, Dae-Song; Nelson, Piper L; Joseph, Biny K; Rhee, Sung W

    2015-09-01

    Postsynaptic density-95 (PSD95) is a scaffolding protein in cerebral vascular smooth muscle cells (cVSMCs), which binds to Shaker-type K(+) (KV1) channels and facilitates channel opening through phosphorylation by protein kinase A. β1-Adrenergic receptors (β1ARs) also have a binding motif for PSD95. Functional association of β1AR with KV1 channels through PSD95 may represent a novel vasodilator complex in cerebral arteries (CA). We explored whether a β1AR-PSD95-KV1 complex is a determinant of rat CA dilation. RT-PCR and western blots revealed expression of β1AR in CA. Isoproterenol induced a concentration-dependent dilation of isolated, pressurized rat CA that was blocked by the β1AR blocker CGP20712. Cranial window imaging of middle cerebral arterioles in situ showed isoproterenol- and norepinephrine-induced dilation that was blunted by β1AR blockade. Isoproterenol-induced hyperpolarization of cVSMCs in pressurized CA was blocked by CGP20712. Confocal images of cVSMCs immunostained with antibodies against β1AR and PSD95 indicated strong colocalization, and PSD95 co-immunoprecipitated with β1AR in CA lysate. Blockade of KV1 channels, β1AR or disruption of PSD95-KV1 interaction produced similar blunting of isoproterenol-induced dilation in pressurized CA. These findings suggest that PSD95 mediates a vasodilator complex with β1AR and KV1 channels in cVSMCs. This complex may be critical for proper vasodilation in rat CA.

  7. Production of the active antifungal Pisum sativum defensin 1 (Psd1) in Pichia pastoris: overcoming the inefficiency of the STE13 protease.

    Science.gov (United States)

    Cabral, Kátia M S; Almeida, Marcius S; Valente, Ana Paula; Almeida, Fábio C L; Kurtenbach, Eleonora

    2003-09-01

    Plant defensins are small cysteine-rich proteins that present high activity against fungi and bacteria and inhibition of insect proteases and alpha-amylases. Here, we present the expression in Pichia pastoris, purification and characterization of the recombinant Pisum sativum defensin 1(rPsd1); a pea defensin which presents four disulfide bridges and high antifungal activity. For this, we had to overcome the inefficiency of the STE13 protease. Our strategy was to clone the corresponding cDNA directly in-frame with a variant of the widely used secretion signal from the Saccharomyces cerevisiae alpha-mating factor, devoid of the STE13 proteolytic signal cleavage sequence. Using an optimized expression protocol, which included a buffered basal salt media formulation, it was possible to obtain about 63.0mg/L of 15N-labeled and unlabeled rPsd1. The recombinants were purified to homogeneity by gel filtration chromatography, followed by reversed-phase HPLC. Mass spectrometry of native and recombinant Psd1 revealed that the protein expressed heterologously was post-translationally processed to the same mature protein as the native one. Circular dichroism and nuclear magnetic resonance spectroscopy analysis indicated that the recombinant protein had the same folding when compared to native Psd1. In addition, the rPsd1 was fully active against Aspergillus niger, if compared with native Psd1. To our knowledge, this is the first heterologous expression of a fully active plant defensin in a high-yield flask.

  8. DA Negatively Regulates IGF-I Actions Implicated in Cognitive Function via Interaction of PSD95 and nNOS in Minimal Hepatic Encephalopathy

    Directory of Open Access Journals (Sweden)

    Saidan Ding

    2017-09-01

    Full Text Available Insulin-like growth factor I (IGF-I has been positively correlated with cognitive ability. Cognitive decline in minimal hepatic encephalopathy (MHE was shown to be induced by elevated intracranial dopamine (DA. The beneficial effect of IGF-I signaling in MHE remains unknown. In this study, we found that IGF-I content was reduced in MHE rats and that IGF-I administration mitigated cognitive decline of MHE rats. A protective effect of IGF-I on the DA-induced interaction between postsynaptic density protein 95 (PSD95 and neuronal nitric oxide synthase (nNOS was found in neurons. Ribosomal S6 protein kinase (RSK phosphorylated nNOS in response to IGF-I by recruiting extracellular signal-regulated kinase (ERK1/2. In turn, DA inactivated the ERK1/2/RSK pathway and stimulated the PSD95–nNOS interaction by downregulating IGF-I. Inhibition of the interaction between PSD95 and nNOS ameliorated DA-induced memory impairment. As DA induced deficits in the ERK1/2/RSK pathway and the interaction between PSD95 and nNOS in MHE brains, IGF-I administration exerted a protective effect via interruption of the interaction between PSD95 and nNOS. These results suggest that IGF-I antagonizes DA-induced cognitive loss by disrupting PSD95–nNOS interactions in MHE.

  9. On The Living Room

    Directory of Open Access Journals (Sweden)

    Thomas Richards

    2013-03-01

    Full Text Available This text discusses the work The Living Room, directed by the author, and reflects on its meanings and functions. The article confronts problems performance raises in relation to contemporary social life, bringing forward the isolation of life today and the possibilities performance offers to fight it. We problematise the crisis experienced by the author and the consequent creation of the work as a mobile performative device in relation to the staging space. Finally, the work questions the forms of interaction and type of participation possible in performance.

  10. Making room for volunteers

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Kleis

    2012-01-01

    If campaigns do not accommodate this view, all but a hard core of regulars and fired-up partisans will drift away, leaving it for staffers and hired hands to do all the hard work of identifying voters, canvassing people by foot and by phone, and turning out the vote. [...] ironically, a campaign...... that is singleminded in its instrumental pursuit of victory can thus be less effective than one that is more accommodating- a campaign that makes room for volunteers by accepting that, unlike staffers, they come to politics with a different perspective and conception of what is and ought to be going on....

  11. Room Temperature Curing Polymers

    Science.gov (United States)

    1977-05-01

    UJ LU LU LU UJ LU W -Q U "O 26 -- - -■- — ■ ■- ■ MBti ^L. IIIIIIII.IHI.I|.UHI,IW’I»;I.!I"IT,U» mpwi«ŕ "^Wl be 190,000 psi which is consistent...was added to the mixture. After 1 hour benzene and water were added and the mixture was stirred until the salt was dissolved. The organic ...for 15 minutes and then cooled to room temperature. The mixture was extracted with two 100 ml portions of water. The organic layer was dried (MgS04

  12. Decrease in neuronal nicotinic acetylcholine receptor subunit and PSD-93 transcript levels in the male mouse MPG after cavernous nerve injury or explant culture

    Science.gov (United States)

    Girard, Beatrice M.; Merriam, Laura A.; Tompkins, John D.; Vizzard, Margaret A.

    2013-01-01

    Quantitative real-time PCR was used to test whether cavernous nerve injury leads to a decrease in major pelvic ganglia (MPG) neuronal nicotinic ACh receptor (nAChR) subunit and postsynaptic density (PSD)-93 transcript levels. Subunits α3, β4, and α7, commonly expressed in the MPG, were selected for analysis. After 72 h in explant culture, MPG transcript levels for α3, β4, α7, and PSD-93 were significantly depressed. Three days after cavernous nerve axotomy or crush in vivo, transcript levels for α3, β4, and PSD-93, but not for α7, were significantly depressed. Three days after dissection of the cavernous nerve free of underlying tissue and application of a 5-mm lateral stretch (manipulation), transcript levels for α3 and PSD-93 were also significantly decreased. Seven days after all three surgical procedures, α3 transcript levels remained depressed, but PSD-93 transcript levels were still decreased only after axotomy or nerve crush. At 30 days postsurgery, transcript levels for the nAChR subunits and PSD-93 had recovered. ACh-induced currents were significantly smaller in MPG neurons dissociated from 3-day explant cultured ganglia than from those recorded in neurons dissociated from acutely isolated ganglia; this observation provides direct evidence showing that a decrease in nAChR function was coincident with a decrease in nAChR subunit transcript levels. We conclude that a downregulation of nAChR subunit and PSD-93 expression after cavernous nerve injury, or even manipulation, could interrupt synaptic transmission within the MPG and thus contribute to the loss of neural control of urogenital organs after pelvic surgeries. PMID:24049141

  13. Mapping out Map Libraries

    Directory of Open Access Journals (Sweden)

    Ferjan Ormeling

    2008-09-01

    Full Text Available Discussing the requirements for map data quality, map users and their library/archives environment, the paper focuses on the metadata the user would need for a correct and efficient interpretation of the map data. For such a correct interpretation, knowledge of the rules and guidelines according to which the topographers/cartographers work (such as the kind of data categories to be collected, and the degree to which these rules and guidelines were indeed followed are essential. This is not only valid for the old maps stored in our libraries and archives, but perhaps even more so for the new digital files as the format in which we now have to access our geospatial data. As this would be too much to ask from map librarians/curators, some sort of web 2.0 environment is sought where comments about data quality, completeness and up-to-dateness from knowledgeable map users regarding the specific maps or map series studied can be collected and tagged to scanned versions of these maps on the web. In order not to be subject to the same disadvantages as Wikipedia, where the ‘communis opinio’ rather than scholarship, seems to be decisive, some checking by map curators of this tagged map use information would still be needed. Cooperation between map curators and the International Cartographic Association ( ICA map and spatial data use commission to this end is suggested.

  14. Mapping soil magnetic susceptibility and mineralogy in Ukraine

    Science.gov (United States)

    Menshov, Oleksandr; Pereira, Paulo; Kruglov, Oleksandr; Sukhorada, Anatoliy

    2017-04-01

    Soil suatainable planning is fundamental for agricultural areas. Soil mapping and modeling are increasingly used in agricultural areas in the entire world (Brevik et al., 2016). They are beneficial to land managers, to reduce soil degradation, increase soil productivity and their restoration. Magnetic susceptibility (MS) methods are low cost and accurate for the developing maps of agricultural areas.. The objective of this work is to identify the minerals responsible for MS increase in soils from the two study areas in Poltava and Kharkiv region. The thermomagnetic analyses were conducted using the KLY-4 with an oven apparatus. The hysteresis parameters were measured with the Rotating Magnetometer at the Geophysical Centre Dourbes, Belgium. The results showed that all of samples from Kharkiv area and the majortity of the samples collected in Poltava area represent the pseudo single domain (PSD) zone particles in Day plot. According to Hanesch et al. (2006), the transformation of goethite, ferrihydrite or hematite to a stronger ferrimagnetic phase like magnetite or maghemite is common in strongly magnetic soils with high values of organic carbon content. In our case of thermomagnetic study, the first peak on the heating curve near 260 ˚C indicates the presence of ferrihydrite which gradually transforms into maghemite (Jordanova et al., 2013). A further decrease in the MS identified on the heating curve may be related to the transformation of the maghemite to hematite. A second MS peak on the heating curve near 530 ˚C and the ultimate loss of magnetic susceptibility near 580 ˚C were caused by the reduction of hematite to magnetite. The shape of the thermomagnetic curves suggests the presence of single domain (SD) particles at room temperature and their transformation to a superparamagnetic (SP) state under heating. Magnetic mineralogical analyses suggest the presence of highly magnetic minerals like magnetite and maghemite as well as slightly magnetic goethite

  15. Binaural room simulation

    Science.gov (United States)

    Lehnert, H.; Blauert, Jens; Pompetzki, W.

    1991-01-01

    In every-day listening the auditory event perceived by a listener is determined not only by the sound signal that a sound emits but also by a variety of environmental parameters. These parameters are the position, orientation and directional characteristics of the sound source, the listener's position and orientation, the geometrical and acoustical properties of surfaces which affect the sound field and the sound propagation properties of the surrounding fluid. A complete set of these parameters can be called an Acoustic Environment. If the auditory event perceived by a listener is manipulated in such a way that the listener is shifted acoustically into a different acoustic environment without moving himself physically, a Virtual Acoustic Environment has been created. Here, we deal with a special technique to set up nearly arbitrary Virtual Acoustic Environments, the Binaural Room Simulation. The purpose of the Binaural Room Simulation is to compute the binaural impulse response related to a virtual acoustic environment taking into account all parameters mentioned above. One possible way to describe a Virtual Acoustic Environment is the concept of the virtual sound sources. Each of the virtual sources emits a certain signal which is correlated but not necessarily identical with the signal emitted by the direct sound source. If source and receiver are non moving, the acoustic environment becomes a linear time-invariant system. Then, the Binaural Impulse Response from the source to a listener' s eardrums contains all relevant auditory information related to the Virtual Acoustic Environment. Listening into the simulated environment can easily be achieved by convolving the Binaural Impulse Response with dry signals and representing the results via headphones.

  16. Response to Request for Guidance on PSD Definition Referencing Cogeneration Gas Turbines that are Separated by One-Half Mile

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  17. Determination of the Applicability of NSPS and PSD to Stationary Gas Turbines Converting From Middle Distillates to Natural Gas

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  18. Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats

    DEFF Research Database (Denmark)

    Sommer, Jens Bak; Bach, Anders; Rytter, Hana Malá

    2017-01-01

    be an effective therapeutic strategy in TBI. The objectives of the present study were to assess the effects of a dimeric inhibitor of PSD-95, UCCB01-144, on excitotoxic cell death in vitro and outcome after experimental TBI in rats in vivo. In addition, the pharmacokinetic parameters of UCCB01-144 were...... assessed in a water maze at two weeks post-trauma, and at four weeks lesion volumes were estimated. Overall, UCCB01-144 did not protect against NMDA-toxicity in neuronal cultures or experimental TBI in rats. Important factors that should be investigated further in future studies assessing the effects...

  19. PSD Applicability Analysis for a Past Change at the Georgia-Pacific Taylorsville Facility Particleboard Plant, Taylorsville, Mississippi

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  20. Recent Development in the ATLAS Control Room

    CERN Multimedia

    Armen Vartapetian

    Only recently the name ATLAS Control Room (ACR) was more associated with the building at Point 1 (SCX1) than with the real thing. But just within the last several months, with the installation of the ACR hardware, that perception has changed significantly. The recently furnished ATLAS control room. But first of all, if you are not familiar with the ATLAS experimental site and are interested in visiting the ATLAS control room to see the place that in the near future will become the brain of the detector operations, it is quite easy to do so. You don't even need safety helmet or shoes! The ACR is located on the ground floor of a not so typical, glass-covered building in Point 1. The building number on the CERN map is 3162, or SCX1 as we call it. It is also easy to recognize that building by its shiny appearance within the cluster of Point 1 buildings if you are driving from Geneva. Final design and prototyping of the ACR hardware started at the beginning of 2006. Evaluation of the chosen hardware confi...

  1. Indoor Positioning System Based on a PSD Detector, Precise Positioning of Agents in Motion Using AoA Techniques.

    Science.gov (United States)

    Rodríguez-Navarro, David; Lázaro-Galilea, José Luis; De-La-Llana-Calvo, Álvaro; Bravo-Muñoz, Ignacio; Gardel-Vicente, Alfredo; Tsirigotis, Georgios; Iglesias-Miguel, Juan

    2017-09-15

    Here, we present an indoor positioning system (IPS) for detecting mobile agents based on a single Position Sensitive Device sensor (PSD) sited in the environment and InfraRed Emitter Diode (IRED) located on mobile agents. The main goal of the work is to develop an alternative IPS to other sensing technologies, cheaper, easier to install and with a low computational load to obtain a high rate of measurements per second. The proposed IPS has the capacity to accurately determine 3D position from the angle of arrival (AoA) of the signal received at the PSD sensor. In this first approach to the method, the agents are considered to move along a plane. We propose two alternatives for determining position: in one, tones are emitted on a frequency unique to each transmitter, while in the other, sequences are emitted.The paper proposes and set up a very simple and easy to deploy system capable of performing 3D positioning with a single analog sensor, obtaining a high accurate positioning and a reduced execution time for the signal processing. The low computational load of the IPS makes it possible to obtain a very high position update rate (more than 100 times per second), yielding millimetric accuracies.

  2. More room for ISOLDE

    CERN Multimedia

    2005-01-01

    To meet the needs of the new ISOLDE experiments, a new extension has been added to the facility's Building 170. The new extension to Building 170. Moving around the ISOLDE hall was almost like an obstacle course until now. The facility's Building 170 simply didn't have an inch to spare and the ISOLDE team's need to set up new experiments, whose installation could have created difficulties from the safety point of view, only exacerbated the problem. "We had ambitious plans to develop new experiments but no room for them", says Mats Lindroos, ISOLDE's technical coordinator. The only solution was to extend the existing building". This was how a new building saw the light of day. Measuring 24 metres long, 20 metres wide and 12 metres high, it is an extension to the existing Building 170 and should be ready for use this year. The new structure makes use of the existing infrastructure, with part of the end wall of Building 170 being kept as a support for steel platforms. The top of this wall had to be cut away ...

  3. The microtubule-associated protein 1A (MAP1A) is an early molecular target of soluble Aβ-peptide

    DEFF Research Database (Denmark)

    Clemmensen, C; Aznar, S; Knudsen, G M

    2012-01-01

    ) protein, proposing that microtubule perturbations might be central for the Aβ-induced neuronal dysfunctions as PSD-95 plays a key role in synaptic plasticity. In conclusion, this study suggests that disruption of MAP1A could be a very early manifestation of Aβ-mediated synaptic dysfunction...... that microtubule rearrangements may be proximate to neuritic degeneration and deficits in episodic declarative memory. Here, we examined primary cortical neurons for changes in markers associated with synaptic function following exposure to sublethal concentrations of non-aggregated Aβ-peptide. This data show...... that soluble Aβ species at a sublethal concentration induce degradation of the microtubule-associated protein 1A (MAP1A) without concurrently affecting dendritic marker MAP2 and/or the pre-synaptic marker synaptophysin. In addition, MAP1A was found to highly co-localize with the postsynaptic density-95 (PSD-95...

  4. Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions

    DEFF Research Database (Denmark)

    Bach, Anders

    2015-01-01

    ZL006 and IC87201 have been presented as efficient inhibitors of the nNOS/PSD-95 protein-protein interaction and shown great promise in cellular experiments and animal models of ischemic stroke and pain. Here, we investigate the proposed mechanism of action of ZL006 and IC87201 using biochemical...... and biophysical methods, such as fluorescence polarization (FP), isothermal titration calorimetry (ITC), and (1)H-(15)N HSQC NMR. Our data show that under the applied in vitro conditions, ZL006 and IC87201 do not interact with the PDZ domains of nNOS or PSD-95, nor inhibit the nNOS-PDZ/PSD-95-PDZ interface...... by interacting with the β-finger of nNOS-PDZ. Our findings have implications for further medicinal chemistry efforts of ZL006, IC87201 and analogues, and challenge the general and widespread view on their mechanism of action....

  5. Investigation of the Deposition and Densification Parameters on the Mechanical Properties of Pressurized Spray Deposited (PSD) 3-D Printed Ceramic Components

    Energy Technology Data Exchange (ETDEWEB)

    Menchhofer, Paul A [ORNL; Becker, Benjamin [Hot End Works

    2016-07-28

    Oak Ridge National Laboratory (ORNL) and HotEnd Works teamed to investigate the use of pressurized spray deposition (PSD) technology for the production of ceramic parts via additive manufacturing. Scanning electron microscopy of sintered parts provided by HotEnd Works revealed voids large enough to compromise the mechanical properties of PSD manufactured parts. Scanning electron microscopy and particle size analysis of the alumina oxide powder feedstocks indicated that the powders contained some large particles and some agglomerations in the powder. Further classification of the powder feedstocks and removal of the agglomerates by sonication in the liquid used for the PSD process are recommended. Analysis of sintered parts indicated that the sonic modulus for the alumina part is consistent with other known values for alumina. The density for this part was determined by standard Archimedes immersion density methods and was found to be > 99.7 % of the theoretical density for pure alumina.

  6. Madness in Sartre's "The Room"

    NARCIS (Netherlands)

    Jongeneel, E.C.S.

    2009-01-01

    In "The Room," part of his short story collection, The Wall (1938), Jean-Paul Sartre investigates madness as an alternative way of bourgeois life and thus takes a stand in the contemporary debate on the existential status of mental illness. "The Room" is a case-study of a "limit situation," as well

  7. Modeling perceptual effects of reverberation on stereophonic sound reproduction in rooms.

    Science.gov (United States)

    Zarouchas, Thomas; Mourjopoulos, John

    2009-07-01

    The proposed model derives time-frequency maps to estimate perceived alterations due to reverberation in stereo audio signals reproduced in rooms. These alterations relate to monaural masking due to reverberant decay, derived via a computational auditory masking model and to inter-channel cues for the formation of the spatial position of the aural objects, derived via an inter-channel cue mapping module. The maps illustrate in detail the varying nature of the perceptually-relevant alterations due to room reverberation. Quantitative metrics are also introduced which were found to be proportional to reverberation interference, to room-reverberation time and to depend on the specific audio signal. A statistical approach classifies room response properties via their histogram distributions. Corresponding distributions were also applied to the proposed signal-dependent perceptual maps. Such distributions were found to be useful for interpreting the perceived alterations with different kinds of signals, such as music or speech.

  8. PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.

    Directory of Open Access Journals (Sweden)

    Fernando J Bustos

    Full Text Available Considerable evidence indicates that the NMDA receptor (NMDAR subunits NR2A and NR2B are critical mediators of synaptic plasticity and dendritogenesis; however, how they differentially regulate these processes is unclear. Here we investigate the roles of the NR2A and NR2B subunits, and of their scaffolding proteins PSD-95 and SAP102, in remodeling the dendritic architecture of developing hippocampal neurons (2-25 DIV. Analysis of the dendritic architecture and the temporal and spatial expression patterns of the NMDARs and anchoring proteins in immature cultures revealed a strong positive correlation between synaptic expression of the NR2B subunit and dendritogenesis. With maturation, the pruning of dendritic branches was paralleled by a strong reduction in overall and synaptic expression of NR2B, and a significant elevation in synaptic expression of NR2A and PSD95. Using constructs that alter the synaptic composition, we found that either over-expression of NR2B or knock-down of PSD95 by shRNA-PSD95 augmented dendritogenesis in immature neurons. Reactivation of dendritogenesis could also be achieved in mature cultured neurons, but required both manipulations simultaneously, and was accompanied by increased dendritic clustering of NR2B. Our results indicate that the developmental increase in synaptic expression of PSD95 obstructs the synaptic clustering of NR2B-NMDARs, and thereby restricts reactivation of dendritic branching. Experiments with shRNA-PSD95 and chimeric NR2A/NR2B constructs further revealed that C-terminus of the NR2B subunit (tail was sufficient to induce robust dendritic branching in mature hippocampal neurons, and suggest that the NR2B tail is important in recruiting calcium-dependent signaling proteins and scaffolding proteins necessary for dendritogenesis.

  9. A largely diffuse small room

    Science.gov (United States)

    Massenburg, George; D'Antonio, Peter

    2005-09-01

    An 8 m×10 m rectangular room is described that will have broad bandwidth diffusion completely covering 5 of its 6 surfaces, i.e., all walls and ceiling surfaces. The dimensions of the room were optimized for minimal standard deviation of the modal response. The wall surfaces are treated with a large prime, single period, number theoretic diffusor 1.2 m deep that wraps around the entire room. The ceiling consists of a 12×13 low frequency diffusor 2 m deep, which is further treated with mid-high frequency diffusors to form a nested, diffractal surface. These surfaces will be described further and illustrated. The room is intended to be deployed as a monitor room for mixing surround sound. It is hoped that the unique combination of a reduced number of specular surfaces and very neutral, wide-band ambience will improve localization (particularly for virtual sources) and offer greater support for (and speed up) the balancing/mixing of multitrack sources. The perceived effectiveness of the diffusor in the ceiling, particularly in the 2 low octaves will be described. The room will also be used as a massively diffuse recording room for various musical formats.

  10. In the LEAR control room

    CERN Multimedia

    CERN PhotoLab

    1983-01-01

    View into the control room of the Low Energy Antiproton Ring (LEAR). Edgar Asseo (sitting) and Dieter Möhl and Georges Carron reflecting upon some beam dynamics (or hardware?) problem. Vassilis Agoritsas, in the background, leaning over a plan or a keyboard. LEAR in its early years (1982 to about 1990) was run from this local control room in building 363 close to the end of the PS South Hall, where the ring was installed. Later-on the operation was surveyed from the PS main control room.

  11. p-sd Shell Gap Reduction in Neutron-Rich Systems and Cross-ShellExcitations in 20O

    Energy Technology Data Exchange (ETDEWEB)

    Wiedeking, M.; Tabor, S.L.; Pavan, J.; Volya, A.; Aguilar, A.L.; Calderin, I.J.; Campbell, D.B.; Cluff, W.T.; Diffenderfer, E.; Fridmann,J.; Hoffman, C.R.; Kemper, K.W.; Lee, S.; Riley, M.A.; Roeder, B.T.; Teal, C.; Tripathi, V.; Wiedenhover, I.

    2005-04-07

    Excited states in {sup 20}O were populated in the reaction {sup 10}Be({sup 14}C,{alpha}) at Florida State University (FSU). Charged particles were detected with a particle telescope consisting of 4 annularly segmented Si surface barrier detectors and {gamma} radiation was detected with the FSU {gamma} detector array. Five new states were observed below 6 MeV from the {alpha}-{gamma} and {alpha}-{gamma}-{gamma} coincidence data. Shell model calculations suggest that most of the newly observed states are core-excited 1p-1h excitations across the N=Z=8 shell gap. Comparisons between experimental data and calculations for the neutron-rich O and F isotopes imply a steady reduction of the p-sd shell gap as neutrons are added.

  12. Topographical map series in the Map Room of Institute and Museum of Military History in Budapest, Hungary between 1919-1945: Larger scales series (1:25,000, 1:50,000, 1:75,000) in the changing territory of Hungary

    Science.gov (United States)

    Jankó, A.; Bánfi, R.

    2009-04-01

    The first independent Hungarian cartographical organization, the Hungarian Military Mapping Group (Magyar Katonai Térképező Csoport), came into being in 1919, the next organization to be established was the Royal Hungarian State Mapping Institute (Magyar Királyi Állami Térképészet) in 1922 (Institute of Military Cartography [Honvéd Térképészeti Intézet] after 1938). These authorities kept the scaling and the scale 1:25,000 sheets of the third military survey of the Austro-Hungarian Monarchy between 1869 and 1887, but its data must have been refreshed; therefore local correction (re-ambulation) and later, in 1927, a new survey were conducted. Further local corrections were initiated by 1939-1940 of the sheets of the southern and eastern borders. As a result of the revisions less than fifty per cent of Hungary's territory became surveyed. The supervised sheets were circulated in multi-colour versions while those not refreshed were issued as reprints of the third military survey in black and white editions. The results of the supervisions were transferred onto the scale 1:75,000 maps as well. During the World War II (1940-1945) in the scale 1:50,000 403 sheets were produced of Hungary (together with territories reattached to the country between 1938-1941.

  13. CDRH FOIA Electronic Reading Room

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CDRH FOIA electronic reading room contains frequently requested information via the Freedom of Information Act from the Center for Devices and Radiological Health.

  14. FRET-FLIM investigation of PSD95-NMDA receptor interaction in dendritic spines; control by calpain, CaMKII and Src family kinase.

    Directory of Open Access Journals (Sweden)

    Kim Doré

    Full Text Available Little is known about the changes in protein interactions inside synapses during synaptic remodeling, as their live monitoring in spines has been limited. We used a FRET-FLIM approach in developing cultured rat hippocampal neurons expressing fluorescently tagged NMDA receptor (NMDAR and PSD95, two essential proteins in synaptic plasticity, to examine the regulation of their interaction. NMDAR stimulation caused a transient decrease in FRET between the NMDAR and PSD95 in spines of young and mature neurons. The activity of both CaMKII and calpain were essential for this effect in both developmental stages. Meanwhile, inhibition of Src family kinase (SFK had opposing impacts on this decrease in FRET in young versus mature neurons. Our data suggest concerted roles for CaMKII, SFK and calpain activity in regulating activity-dependent separation of PSD95 from GluN2A or GluN2B. Finally, we found that calpain inhibition reduced spine growth that was caused by NMDAR activity, supporting the hypothesis that PSD95-NMDAR separation is implicated in synaptic remodeling.

  15. A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    DEFF Research Database (Denmark)

    Bach, Anders*; Clausen, Bettina H; Møller, Magda

    2012-01-01

    Inhibition of the ternary protein complex of the synaptic scaffolding protein postsynaptic density protein-95 (PSD-95), neuronal nitric oxide synthase (nNOS), and the N-methyl-d-aspartate (NMDA) receptor is a potential strategy for treating ischemic brain damage, but high-affinity inhibitors...

  16. Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment.

    Science.gov (United States)

    Whitfield, David R; Vallortigara, Julie; Alghamdi, Amani; Howlett, David; Hortobágyi, Tibor; Johnson, Mary; Attems, Johannes; Newhouse, Stephen; Ballard, Clive; Thomas, Alan J; O'Brien, John T; Aarsland, Dag; Francis, Paul T

    2014-12-01

    The loss of zinc transporter 3 (ZnT3) has been implicated in age-related cognitive decline in mice, and the protein has been associated with plaques. We investigated the levels of ZnT3 and postsynaptic density protein 95 (PSD95), a marker of the postsynaptic terminal, in people with Parkinson's disease dementia (PDD, n = 31), dementia with Lewy bodies (DLB, n = 44), Alzheimer's disease (AD, n = 16), and controls (n = 24), using semiquantitative western blotting and immunohistochemistry in 3 cortical regions. Standardized cognitive assessments during life and semiquantitative scoring of amyloid β (Aβ), tau, and α-synuclein at postmortem were used to investigate the relationship between ZnT3 and PSD95, cognition and pathology. Associations were observed between ZnT3 and PSD95 levels in prefrontal cortex and cognitive impairment (p = 0.001 and p = 0.002, respectively) and between ZnT3 levels in the parietal cortex and cognitive impairment (p = 0.036). Associations were also seen between ZnT3 levels in cingulate cortex and severity of Aβ (p = 0.003) and tau (p = 0.011) pathologies. DLB and PDD were characterized by significant reductions of PSD95 (p < 0.05) and ZnT3 (p < 0.001) in prefrontal cortex compared with controls and AD. PSD95 levels in the parietal cortex were found to be decreased in AD cases compared with controls (p = 0.02) and PDD (p = 0.005). This study has identified Zn(2+) modulation as a possible novel target for the treatment of cognitive impairment in DLB and PDD and the potential for synaptic proteins to be used as a biomarker for the differentiation of DLB and PDD from AD. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Comparing the performance of various digital soil mapping approaches to map physical soil properties

    Science.gov (United States)

    Laborczi, Annamária; Takács, Katalin; Pásztor, László

    2015-04-01

    Spatial information on physical soil properties is intensely expected, in order to support environmental related and land use management decisions. One of the most widely used properties to characterize soils physically is particle size distribution (PSD), which determines soil water management and cultivability. According to their size, different particles can be categorized as clay, silt, or sand. The size intervals are defined by national or international textural classification systems. The relative percentage of sand, silt, and clay in the soil constitutes textural classes, which are also specified miscellaneously in various national and/or specialty systems. The most commonly used is the classification system of the United States Department of Agriculture (USDA). Soil texture information is essential input data in meteorological, hydrological and agricultural prediction modelling. Although Hungary has a great deal of legacy soil maps and other relevant soil information, it often occurs, that maps do not exist on a certain characteristic with the required thematic and/or spatial representation. The recent developments in digital soil mapping (DSM), however, provide wide opportunities for the elaboration of object specific soil maps (OSSM) with predefined parameters (resolution, accuracy, reliability etc.). Due to the simultaneous richness of available Hungarian legacy soil data, spatial inference methods and auxiliary environmental information, there is a high versatility of possible approaches for the compilation of a given soil map. This suggests the opportunity of optimization. For the creation of an OSSM one might intend to identify the optimum set of soil data, method and auxiliary co-variables optimized for the resources (data costs, computation requirements etc.). We started comprehensive analysis of the effects of the various DSM components on the accuracy of the output maps on pilot areas. The aim of this study is to compare and evaluate different

  18. Operating room central serous chorioretinopathy.

    Science.gov (United States)

    Mansour, Ahmad M; Hamam, Rola

    2017-01-01

    The operating room is a place of surgical intervention with its accompanying bodily and cognitive strain on the performers. Stress in the operating room may lead to the onset of central serous chorioretinopathy as reported hereby in a retina surgeon and is labeled as operating room central serous chorioretinopathy. The same operator performed the optical coherence tomography scans on one retina surgeon. A masked observer estimated the maximal height of the subretinal fluid. Central serous chorioretinopathy recurred four times over a 1-year period 1 -2 days after a stressful day in the operating room, especially when cases were done under topical or subtenon anesthesia for cataract surgery, vitreous surgery or combined surgeries with complex ocular and medical problems and inability for anesthesia team to intervene. Stress management allowed resolution of subretinal fluid between 3 and 4 weeks. Adopting this strategy, no further attacks were documented by optical coherence tomography for 5 years. (1) This is one of a few optical coherence tomography documentation of resolution of central serous chorioretinopathy within 3-4 weeks of its occurrence and its recurrence induced by stress in the operating room; (2) Unassisted topical anesthesia required in patients with complex medical and ocular problems causes more cognitive stress than when surgery is carried under assisted local or general anesthesia (partly due to unexpected ocular or bodily movements); and (3) the available evidence suggests that those overcommitted surgeons (type A personality) may very well be most susceptible to burnout and central serous chorioretinopathy.

  19. [Working conditions in operating rooms].

    Science.gov (United States)

    Kułagowska, Ewa

    2007-01-01

    The aim of this study was to get acquainted with the opinions of the nursing staff on working conditions at their workplace. The study was carried out in a group of 398 nurses working in various kinds of operating rooms at 11 public hospitals. A questionnaire was used as a major tool of this study. The questionnaires were filled in by 259 operating room nurses (circulating nurses) and 139 nurse-anesthetists. The collected data show that working conditions in operating rooms do not ensure safety of the nursing staff at work. The main sources of problems are: work organization, technical factors, work equipment, work space, knowledge of hazards and strenuous factors among nurses, ways of preventing and/or limiting them. These elements are serious occupational risk factors influencing the work process and health status of nurses.

  20. 32 CFR 296.6 - Reading room.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Reading room. 296.6 Section 296.6 National... Reading room. (a) The NRO shall provide a reading room equipped with hard copy and electronic records as required in the “Electronic Freedom of Information Act Amendments of 1996”. The NRO Reading Room is located...

  1. 39 CFR 3004.12 - Reading room.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Reading room. 3004.12 Section 3004.12 Postal... Reading room. (a) The Commission maintains a public reading room at its offices (901 New York Avenue, NW., Suite 200, Washington, DC 20268-0001) and an electronic reading room at http://www.prc.gov. The public...

  2. Cognitive maps

    OpenAIRE

    Kitchin, Rob

    2001-01-01

    A cognitive map is a representative expression of an individual's cognitive map knowledge, where cognitive map knowledge is an individual's knowledge about the spatial and environmental relations of geographic space. For example, a sketch map drawn to show the route between two locations is a cognitive map — a representative expression of the drawer's knowledge of the route between the two locations. This map can be analyzed using classification schemes or quantitatively using spatial statist...

  3. Thermal plumes in ventilated rooms

    DEFF Research Database (Denmark)

    Kofoed, Peter; Nielsen, Peter V.

    1990-01-01

    The design of a displacement ventilation system involves determination of the flow rate in the thermal plumes. The flow rate in the plumes and the vertical temperature gradient influence each other, and they are influenced by many factors. This paper shows some descriptions of these effects. Free...... to be the only possible approach to obtain the volume flow in: thermal plumes in ventilated rooms....

  4. Kids’ rooms as plus territory

    DEFF Research Database (Denmark)

    Winther, Ida

    2006-01-01

    they domesticate, capture territories and places. What do our children do to get place, space and rooms, which belong to them? How do they do home? ?To home oneself? can be understood as a self-technology or a tactic (de Certeau, 1984), a tactic to make space around oneself on the places one stay. A way to commit...

  5. New Radiation Protection training room

    CERN Multimedia

    HSE Unit

    2013-01-01

    From now on, the theory and practical components of the Radiation Protection training, developed by the RP Group and offered by the HSE Unit’s Safety Training team to people working in a Controlled Radiation Area, will take place in a dedicated teaching room, designed specifically for this kind of training.   The new room is in the Safety Training Centre on the Prévessin site and has been open since 16 October. It has an adjoining workshop that, like the room itself, can accommodate up to 12 people. It is also equipped with an interactive board as well as instruments and detectors to test for ionising radiation. This room is located near the recently inaugurated LHC tunnel mock-up where practical training exercises can be carried out in conditions almost identical to those in the real tunnel. To consult the safety training catalogue and/or sign up for Radiation Protection training, please go to: https://cta.cern.ch For further information, please contact the Safety Trainin...

  6. Hotels Make Room for Fitness.

    Science.gov (United States)

    Koszuta, Laurie Einstein

    1986-01-01

    Hotels, in hopes of gaining a competitive edge, are offering workout rooms, exercise equipment, fitness trails, and jogging tracks, but no standards have been set for safety of the facilities or staff preparedness in exercise screening, equipment use, injury prevention, or first aid. (MT)

  7. ISOLDE target zone control room

    CERN Multimedia

    2016-01-01

    Operating the ISOLDE target handling robots from the dedicated control room in building 197. Monitors showing the movements of the robots (GPS in this case) in the target zone. The footage shows the actual operation by the operator as well as the different equipment such as camera electronics, camera motor controls, camera monitors and Kuka robot controls touch panel.

  8. Transition Room Program, 1967 Report.

    Science.gov (United States)

    Glassner, Leonard E.

    The Transition Room Program of the Pittsburgh Schools was defined and evaluated by the staff, the administration, and a program evaluator from the Office of Research. The definition included general objectives, anticipated outcomes, student criteria and characteristics, staff qualifications and functions, media, student activities, and staff…

  9. An Optimisation Approach for Room Acoustics Design

    DEFF Research Database (Denmark)

    Holm-Jørgensen, Kristian; Kirkegaard, Poul Henning; Andersen, Lars

    2005-01-01

    This paper discuss on a conceptual level the value of optimisation techniques in architectural acoustics room design from a practical point of view. It is chosen to optimise one objective room acoustics design criterium estimated from the sound field inside the room. The sound field is modeled...... using the boundary element method where absorption is incorporated. An example is given where the geometry of a room is defined by four design modes. The room geometry is optimised to get a uniform sound pressure....

  10. The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions.

    Science.gov (United States)

    Belotti, Edwige; Polanowska, Jolanta; Daulat, Avais M; Audebert, Stéphane; Thomé, Virginie; Lissitzky, Jean-Claude; Lembo, Frédérique; Blibek, Karim; Omi, Shizue; Lenfant, Nicolas; Gangar, Akanksha; Montcouquiol, Mireille; Santoni, Marie-Josée; Sebbagh, Michael; Aurrand-Lions, Michel; Angers, Stéphane; Kodjabachian, Laurent; Reboul, Jérome; Borg, Jean-Paul

    2013-09-01

    Protein-protein interactions organize the localization, clustering, signal transduction, and degradation of cellular proteins and are therefore implicated in numerous biological functions. These interactions are mediated by specialized domains able to bind to modified or unmodified peptides present in binding partners. Among the most broadly distributed protein interaction domains, PSD95-disc large-zonula occludens (PDZ) domains are usually able to bind carboxy-terminal sequences of their partners. In an effort to accelerate the discovery of PDZ domain interactions, we have constructed an array displaying 96% of the human PDZ domains that is amenable to rapid two-hybrid screens in yeast. We have demonstrated that this array can efficiently identify interactions using carboxy-terminal sequences of PDZ domain binders such as the E6 oncoviral protein and protein kinases (PDGFRβ, BRSK2, PCTK1, ACVR2B, and HER4); this has been validated via mass spectrometry analysis. Taking advantage of this array, we show that PDZ domains of Scrib and SNX27 bind to the carboxy-terminal region of the planar cell polarity receptor Vangl2. We also have demonstrated the requirement of Scrib for the promigratory function of Vangl2 and described the morphogenetic function of SNX27 in the early Xenopus embryo. The resource presented here is thus adapted for the screen of PDZ interactors and, furthermore, should facilitate the understanding of PDZ-mediated functions.

  11. In vitro and in vivo effects of a novel dimeric inhibitor of PSD-95 on excitotoxicity and functional recovery after experimental traumatic brain injury

    DEFF Research Database (Denmark)

    Sommer, Jens Bak; Bach, Anders; Rytter, Hana Malá

    2017-01-01

    PSD-95 inhibitors have been shown to be neuroprotective in stroke, but have only to a very limited extent been evaluated in the treatment of traumatic brain injury (TBI) that has pathophysiological mechanisms in common with stroke. The aims of the current study were to assess the effects of a nov...... studies taking important experimental factors such as timing of treatment, dosage, and anesthesia into consideration....

  12. Concept Mapping.

    Science.gov (United States)

    Callison, Daniel

    2001-01-01

    Explains concept mapping as a heuristic device that is helpful in visualizing the relationships between and among ideas. Highlights include how to begin a map; brainstorming; map applications, including document or information summaries and writing composition; and mind mapping to strengthen note-taking. (LRW)

  13. High Dynamics and Precision Optical Measurement Using a Position Sensitive Detector (PSD in Reflection-Mode: Application to 2D Object Tracking over a Smart Surface

    Directory of Open Access Journals (Sweden)

    Ioan Alexandru Ivan

    2012-12-01

    Full Text Available When related to a single and good contrast object or a laser spot, position sensing, or sensitive, detectors (PSDs have a series of advantages over the classical camera sensors, including a good positioning accuracy for a fast response time and very simple signal conditioning circuits. To test the performance of this kind of sensor for microrobotics, we have made a comparative analysis between a precise but slow video camera and a custom-made fast PSD system applied to the tracking of a diffuse-reflectivity object transported by a pneumatic microconveyor called Smart-Surface. Until now, the fast system dynamics prevented the full control of the smart surface by visual servoing, unless using a very expensive high frame rate camera. We have built and tested a custom and low cost PSD-based embedded circuit, optically connected with a camera to a single objective by means of a beam splitter. A stroboscopic light source enhanced the resolution. The obtained results showed a good linearity and a fast (over 500 frames per second response time which will enable future closed-loop control by using PSD.

  14. A Specific Nutrient Combination Attenuates the Reduced Expression of PSD-95 in the Proximal Dendrites of Hippocampal Cell Body Layers in a Mouse Model of Phenylketonuria

    Science.gov (United States)

    Bruinenberg, Vibeke M.; van Vliet, Danique; Attali, Amos; de Wilde, Martijn C.; Kuhn, Mirjam; van Spronsen, Francjan J.; van der Zee, Eddy A.

    2016-01-01

    The inherited metabolic disease phenylketonuria (PKU) is characterized by increased concentrations of phenylalanine in the blood and brain, and as a consequence neurotransmitter metabolism, white matter, and synapse functioning are affected. A specific nutrient combination (SNC) has been shown to improve synapse formation, morphology and function. This could become an interesting new nutritional approach for PKU. To assess whether treatment with SNC can affect synapses, we treated PKU mice with SNC or an isocaloric control diet and wild-type (WT) mice with an isocaloric control for 12 weeks, starting at postnatal day 31. Immunostaining for post-synaptic density protein 95 (PSD-95), a post-synaptic density marker, was carried out in the hippocampus, striatum and prefrontal cortex. Compared to WT mice on normal chow without SNC, PKU mice on the isocaloric control showed a significant reduction in PSD-95 expression in the hippocampus, specifically in the granular cell layer of the dentate gyrus, with a similar trend seen in the cornus ammonis 1 (CA1) and cornus ammonis 3 (CA3) pyramidal cell layer. No differences were found in the striatum or prefrontal cortex. PKU mice on a diet supplemented with SNC showed improved expression of PSD-95 in the hippocampus. This study gives the first indication that SNC supplementation has a positive effect on hippocampal synaptic deficits in PKU mice. PMID:27102170

  15. Space Brightness Evaluation for a Daylit Room

    Directory of Open Access Journals (Sweden)

    Takashi Maruyama

    2011-05-01

    Full Text Available One of the most important problems for lighting design is how to reduce an electric energy. One way to solve this problem is use of daylight, but little is known how to perceive a brightness of a room illuminated by daylight come in through a window and artificial light. Although the horizontal illuminance increases because of daylight, we would not perceive the room as bright as brightness estimated by the illuminance. The purpose of this study is to measure the space brightness for daylit room and to propose a evaluation method. The experiment was conducted with a couple of miniature office rooms, standard room and test room. Test room has several types of windows and standard room has no window. Subject was asked to evaluate the brightness of the test room relative to the standard room with method of magnitude estimation. It was found that brightness of daylit room did not increase simply with horizontal illuminance. Subject perceived a daylit room darker than a room illuminated only by the artificial light even if horizontal illuminance of these room was same. The effect of daylight on space brightness would vary with the window size and intensity of daylight or artificial light.

  16. Concept Maps

    OpenAIRE

    Schwendimann, Beat Adrian

    2014-01-01

    A concept map is a node-link diagram showing the semantic relationships among concepts. The technique for constructing concept maps is called "concept mapping". A concept map consists of nodes, arrows as linking lines, and linking phrases that describe the relationship between nodes. Two nodes connected with a labeled arrow are called a proposition. Concept maps are versatile graphic organizers that can represent many different forms of relationships between concepts. The relationship between...

  17. Aerodynamics simulation of operating rooms

    OpenAIRE

    El Gharbi, Najla; Benzaoui, Ahmed; Bennacer, Rachid

    2006-01-01

    International audience; The hospital is the place where we find simultaneously people whose health state is weakened, or vulnerable, and pathogenic micro-organisms able to worsen their health. Because these, the quality of the air in hospital must be in conformity with precise criteria in the buildings such everyday usage, and in particular in the buildings where some risk of specific pollution exist as in operating rooms. In this paper, we present a modelisation and three dimensional numeric...

  18. Library rooms or Library halls

    OpenAIRE

    Alfredo Serrai

    2013-01-01

    Library Halls, understood as Renaissance and Baroque architectural creations, along with the furnishings and decorations, accomplish a cognitive task and serve to transmit knowledge. The design of these spaces based on the idea that they should reflect the merits and content of the collections housed within them, in order to prepare the mind of the reader to respect and admire the volumes. In accordance with this principle, in the fifteenth century library rooms had a basilican shape, with tw...

  19. 'How To' Clean Room Video

    Science.gov (United States)

    McCarty, Kaley Corinne

    2013-01-01

    One of the projects that I am completing this summer is a Launch Services Program intern 'How to' set up a clean room informational video. The purpose of this video is to go along with a clean room kit that can be checked out by employees at the Kennedy Space Center and to be taken to classrooms to help educate students and intrigue them about NASA. The video will include 'how to' set up and operate a clean room at NASA. This is a group project so we will be acting as a team and contributing our own input and ideas. We will include various activities for children in classrooms to complete, while learning and having fun. Activities that we will explain and film include: helping children understand the proper way to wear a bunny suit, a brief background on cleanrooms, and the importance of maintaining the cleanliness of a space craft. This project will be shown to LSP management and co-workers; we will be presenting the video once it is completed.

  20. Web Interactive Campus Map

    Directory of Open Access Journals (Sweden)

    Marylene S. Eder

    2015-03-01

    Full Text Available Abstract Interactive campus map is a web based application that can be accessed through a web browser. With the Google Map Application Programming Interface availability of the overlay function has been taken advantage to create custom map functionalities. Collection of building points were gathered for routing and to create polygons which serves as a representation of each building. The previous campus map provides a static visual representation of the campus. It uses legends building name and its corresponding building number in providing information. Due to its limited capabilities it became a realization to the researchers to create an interactive campus map.Storing data about the building room and staff information and university events and campus guide are among the primary features that this study has to offer. Interactive Web-based Campus Information System is intended in providing a Campus Information System.It is open to constant updates user-friendly for both trained and untrained users and capable of responding to all needs of users and carrying out analyses. Based on the data gathered through questionnaires researchers analyzed the results of the test survey and proved that the system is user friendly deliver information to users and the important features that the students expect.

  1. Novel room temperature ferromagnetic semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Amita [KTH Royal Inst. of Technology, Stockholm (Sweden)

    2004-06-01

    Today's information world, bits of data are processed by semiconductor chips, and stored in the magnetic disk drives. But tomorrow's information technology may see magnetism (spin) and semiconductivity (charge) combined in one 'spintronic' device that exploits both charge and 'spin' to carry data (the best of two worlds). Spintronic devices such as spin valve transistors, spin light emitting diodes, non-volatile memory, logic devices, optical isolators and ultra-fast optical switches are some of the areas of interest for introducing the ferromagnetic properties at room temperature in a semiconductor to make it multifunctional. The potential advantages of such spintronic devices will be higher speed, greater efficiency, and better stability at a reduced power consumption. This Thesis contains two main topics: In-depth understanding of magnetism in Mn doped ZnO, and our search and identification of at least six new above room temperature ferromagnetic semiconductors. Both complex doped ZnO based new materials, as well as a number of nonoxides like phosphides, and sulfides suitably doped with Mn or Cu are shown to give rise to ferromagnetism above room temperature. Some of the highlights of this work are discovery of room temperature ferromagnetism in: (1) ZnO:Mn (paper in Nature Materials, Oct issue, 2003); (2) ZnO doped with Cu (containing no magnetic elements in it); (3) GaP doped with Cu (again containing no magnetic elements in it); (4) Enhancement of Magnetization by Cu co-doping in ZnO:Mn; (5) CdS doped with Mn, and a few others not reported in this thesis. We discuss in detail the first observation of ferromagnetism above room temperature in the form of powder, bulk pellets, in 2-3 mu-m thick transparent pulsed laser deposited films of the Mn (<4 at. percent) doped ZnO. High-resolution transmission electron microscopy (HRTEM) and electron energy loss spectroscopy (EELS) spectra recorded from 2 to 200nm areas showed homogeneous

  2. Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders

    Directory of Open Access Journals (Sweden)

    Annalisa Alfieri

    2017-06-01

    Full Text Available Altered synaptic function has been associated with neurological and psychiatric conditions including intellectual disability, schizophrenia and autism spectrum disorder (ASD. Amongst the recently discovered synaptic proteins is p140Cap, an adaptor that localizes at dendritic spines and regulates their maturation and physiology. We recently showed that p140Cap knockout mice have cognitive deficits, impaired long-term potentiation (LTP and long-term depression (LTD, and immature, filopodia-like dendritic spines. Only a few p140Cap interacting proteins have been identified in the brain and the molecular complexes and pathways underlying p140Cap synaptic function are largely unknown. Here, we isolated and characterized the p140Cap synaptic interactome by co-immunoprecipitation from crude mouse synaptosomes, followed by mass spectrometry-based proteomics. We identified 351 p140Cap interactors and found that they cluster to sub complexes mostly located in the postsynaptic density (PSD. p140Cap interactors converge on key synaptic processes, including transmission across chemical synapses, actin cytoskeleton remodeling and cell-cell junction organization. Gene co-expression data further support convergent functions: the p140Cap interactors are tightly co-expressed with each other and with p140Cap. Importantly, the p140Cap interactome and its co-expression network show strong enrichment in genes associated with schizophrenia, autism, bipolar disorder, intellectual disability and epilepsy, supporting synaptic dysfunction as a shared biological feature in brain diseases. Overall, our data provide novel insights into the molecular organization of the synapse and indicate that p140Cap acts as a hub for postsynaptic complexes relevant to psychiatric and neurological disorders.

  3. Sea Ice Detection Based on Differential Delay-Doppler Maps from UK TechDemoSat-1.

    Science.gov (United States)

    Zhu, Yongchao; Yu, Kegen; Zou, Jingui; Wickert, Jens

    2017-07-12

    Global Navigation Satellite System (GNSS) signals can be exploited to remotely sense atmosphere and land and ocean surface to retrieve a range of geophysical parameters. This paper proposes two new methods, termed as power-summation of differential Delay-Doppler Maps (PS-D) and pixel-number of differential Delay-Doppler Maps (PN-D), to distinguish between sea ice and sea water using differential Delay-Doppler Maps (dDDMs). PS-D and PN-D make use of power-summation and pixel-number of dDDMs, respectively, to measure the degree of difference between two DDMs so as to determine the transition state (water-water, water-ice, ice-ice and ice-water) and hence ice and water are detected. Moreover, an adaptive incoherent averaging of DDMs is employed to improve the computational efficiency. A large number of DDMs recorded by UK TechDemoSat-1 (TDS-1) over the Arctic region are used to test the proposed sea ice detection methods. Through evaluating against ground-truth measurements from the Ocean Sea Ice SAF, the proposed PS-D and PN-D methods achieve a probability of detection of 99.72% and 99.69% respectively, while the probability of false detection is 0.28% and 0.31% respectively.

  4. Sea Ice Detection Based on Differential Delay-Doppler Maps from UK TechDemoSat-1

    Directory of Open Access Journals (Sweden)

    Yongchao Zhu

    2017-07-01

    Full Text Available Global Navigation Satellite System (GNSS signals can be exploited to remotely sense atmosphere and land and ocean surface to retrieve a range of geophysical parameters. This paper proposes two new methods, termed as power-summation of differential Delay-Doppler Maps (PS-D and pixel-number of differential Delay-Doppler Maps (PN-D, to distinguish between sea ice and sea water using differential Delay-Doppler Maps (dDDMs. PS-D and PN-D make use of power-summation and pixel-number of dDDMs, respectively, to measure the degree of difference between two DDMs so as to determine the transition state (water-water, water-ice, ice-ice and ice-water and hence ice and water are detected. Moreover, an adaptive incoherent averaging of DDMs is employed to improve the computational efficiency. A large number of DDMs recorded by UK TechDemoSat-1 (TDS-1 over the Arctic region are used to test the proposed sea ice detection methods. Through evaluating against ground-truth measurements from the Ocean Sea Ice SAF, the proposed PS-D and PN-D methods achieve a probability of detection of 99.72% and 99.69% respectively, while the probability of false detection is 0.28% and 0.31% respectively.

  5. New thinking for the boiler room.

    Science.gov (United States)

    Rose, Wayne

    2008-09-01

    Wayne Rose, marketing manager at integrated plant room manufacturer Armstrong Integrated Systems, explains how increasing use of off-site manufacture, the latest 3D modelling technology, and advances in control technology, are revolutionising boiler room design and construction.

  6. 32 CFR 701.6 - Reading rooms.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Reading rooms. 701.6 Section 701.6 National... Reading rooms. The FOIA requires that (a)(2) records created on or after 1 November 1996, be made available electronically (starting 1 November 1997) as well as in hard copy, in the FOIA reading room for...

  7. Clean room technology in surgery suites

    Science.gov (United States)

    1971-01-01

    The principles of clean room technology and the criteria for their application to surgery are discussed. The basic types of surgical clean rooms are presented along with their advantages and disadvantages. Topics discussed include: microbiology of surgery suites; principles of laminar airflow systems, and their use in surgery; and asepsis and the operating room.

  8. Auditory modelling for assessing room acoustics

    NARCIS (Netherlands)

    Van Dorp Schuitman, J.

    2011-01-01

    The acoustics of a concert hall, or any other room, are generally assessed by measuring room impulse responses for one or multiple source and receiver location(s). From these responses, objective parameters can be determined that should be related to various perceptual attributes of room acoustics.

  9. An open room for interpretation

    DEFF Research Database (Denmark)

    Tofte-Hansen, Inge

    2015-01-01

    Based on a concept that I have developed, which is called: "An open room for interpretation", the following article states that creative work and aesthetic expression in a pedagogical context with 2-6 years old children must give space for the children's own expressions. To teach music should...... not only be seen as a learning task where initiative and product is defined by the teacher. In contrast, I suggest that creative activities and aesthetic processes must be seen as an interaction between children's immediate physicality and curiosity and the teacher's musical skills and abilities to follow...... and develop the children’s initiative....

  10. Flow in air conditioned rooms

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    1974-01-01

    Flow in air conditioned r ooms is examined by means of model experiments . The different gearnetries giving unsteady, steady three- dimensional and steady twodimensional flow are determined . Velacity profiles and temperature profiles are measured in some of the geometries. A numerical solution...... of the flow equations is demonstrated and the flow in air conditioned rooms in case of steady two dimensional flow is predi cted. Compari son with measured results is shown i n the case of small Archimedes numbers, and predictions are shown at high Archimedes numbers. A numerical prediction of f low and heat...

  11. CEPH maps.

    Science.gov (United States)

    Cann, H M

    1992-06-01

    There are CEPH genetic maps on each homologous human chromosome pair. Genotypes for these maps have been generated in 88 laboratories that receive DNA from a reference panel of large nuclear pedigrees/families supplied by the Centre d'Etude du Polymorphisme Humain. These maps serve as useful tools for the localization of both disease genes and other genes of interest.

  12. Library rooms or Library halls

    Directory of Open Access Journals (Sweden)

    Alfredo Serrai

    2013-12-01

    Full Text Available Library Halls, understood as Renaissance and Baroque architectural creations, along with the furnishings and decorations, accomplish a cognitive task and serve to transmit knowledge. The design of these spaces based on the idea that they should reflect the merits and content of the collections housed within them, in order to prepare the mind of the reader to respect and admire the volumes. In accordance with this principle, in the fifteenth century library rooms had a basilican shape, with two or three naves, like churches, reflecting thus the spiritual value of the books contained there. Next to that inspiring function, library rooms had also the task of representing the entire logical and conceptual universe of human knowledge in a figurative way, including for this purpose also the and Kunst- und Wunderkammern, namely the collections of natural, artficial objects, and works of art. The importance of library rooms and their function was understood already in the early decades of the seventeenth century, as underlined in the treatise, Musei sive Bibliothecae tam privatae quam publicae Extructio, Instructio, Cura, Usus, written by the Jesuit Claude Clément and published in 1635. Almost the entire volume is dedicated to the decoration and ornamentation of the Saloni, and the function of the library is identified exclusively with the preservation and decoration of the collection, neglecting more specifically bibliographic aspects or those connected to library science. The architectural structure of the Saloni was destined to change in relation to two factors, namely the form of books, and the sources of light. As a consequence, from the end of the sixteenth century – or perhaps even before if one considers the fragments of the Library of Urbino belonging to Federico da Montefeltro – shelves and cabinets have been placed no longer in the center of the room, but were set against the walls. This new disposition of the furniture, surmounted by

  13. Dedicated orthopedic operating room unit improves operating room efficiency.

    Science.gov (United States)

    Small, Travis J; Gad, Bishoy V; Klika, Alison K; Mounir-Soliman, Loran S; Gerritsen, Ryan L; Barsoum, Wael K

    2013-08-01

    We investigated the effectiveness of dedicated orthopedic operating rooms (OR) on minimizing time spent on perioperative processes to increase OR throughput in total knee and hip arthroplasty procedures. The use of a dedicated orthopedic unit that included 6 ORs with staff allocated only for those ORs was compared to the use of a traditional staffing model. After matching to simulate randomization, each group consisted of 422 procedures. The dedicated orthopedic unit improved average anesthesia controlled time by 4 minutes (Poperative time by 7 minutes (P=.004) and turnover time by 8 minutes (P<.001). An overall improvement of 19 minutes per procedure using the dedicated unit was observed. Utilizing a dedicated orthopedic unit can save time without increasing adverse events. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Topographic mapping

    Science.gov (United States)

    ,

    2008-01-01

    The U.S. Geological Survey (USGS) produced its first topographic map in 1879, the same year it was established. Today, more than 100 years and millions of map copies later, topographic mapping is still a central activity for the USGS. The topographic map remains an indispensable tool for government, science, industry, and leisure. Much has changed since early topographers traveled the unsettled West and carefully plotted the first USGS maps by hand. Advances in survey techniques, instrumentation, and design and printing technologies, as well as the use of aerial photography and satellite data, have dramatically improved mapping coverage, accuracy, and efficiency. Yet cartography, the art and science of mapping, may never before have undergone change more profound than today.

  15. 'Enjoying the kick': Locating pleasure within the drug consumption room.

    Science.gov (United States)

    Duncan, Tristan; Duff, Cameron; Sebar, Bernadette; Lee, Jessica

    2017-11-01

    Harm reduction policy and praxis has long struggled to accommodate the pleasures of alcohol and other drug use. Whilst scholars have consistently highlighted this struggle, how pleasure might come to practically inform the design and delivery of harm reduction policies and programs remains less clear. The present paper seeks to move beyond conceptual critiques of harm reduction's 'pleasure oversight' to more focused empirical analysis of how flows of pleasure emerge, circulate and, importantly, may be reoriented in the course of harm reduction practice. We ground our analysis in the context of detailed ethnographic research in a drug consumption room in Frankfurt, Germany. Drawing on recent strands of post-humanist thought, the paper deploys the concept of the 'consumption event' to uncover the manner in which these facilities mediate the practice and embodied experience of drug use and incite or limit bodily potentials for intoxication and pleasure. Through the analysis, we mapped a diversity of pleasures as they emerged and circulated through events of consumption at the consumption room. Beyond the pleasurable intensities of intoxication's kick, these pleasures were expressed in a range of novel capacities, practices and drug using bodies. In each instance, pleasure could not be reduced to a simple, linear product of drug use. Rather, it arose for our participants through distinctive social and affective transformations enabled through events of consumption at the consumption room and the generative force of actors and associations of which these events were composed. Our research suggests that the drug consumption room serves as a conduit through which its clients can potentially enact more pleasurable, productive and positive relations to both themselves and their drug use. Acknowledging the centrality of pleasure to client engagement with these facilities, the paper concludes by drawing out the implications of these findings for the design and delivery of

  16. [Effects of electroacupuncture at different acupoints on learning and memory ability and PSD-95 protein expression on hippocampus CA1 in rats with autism].

    Science.gov (United States)

    Zhang, Xue-Jun; Wu, Qiang

    2013-07-01

    To explore the effect mechanism of electroacupuncture (EA) at Changqiang (GV 1) or Baihui (GV 20) on autism based on molecular biology. The autism model was established by intraperitoneal injection of sodium valproate (VPA) in Wistar pregnant rats. Forty young rats with autism were selected and randomly divided into a model group, a non-acupoint group, an electroacupuncture at "Changqiang" (GV 1) (EAGV 1 for short) group and an electroacupuncture at "Baihui" (GV 20) (EAGV 20 for short) group. Another 10 normal young rats were selected as a blank group. In the EAGV 1 group, acupuncture was applied at Houhai [as Changqiang (GV 1)], then EA apparatus was connected with continuous wave, 2 Hz, 20 min, once a day for consecutive 20 days. The same EA manipulation as EAGV 1 group was used in the EAGV 20 group where "Baihui" (GV 20) was selected and non-acupoint group where non-acupoint in the right rib was selected. Blank group and model group were reared under the same conditions without any intervention. The escape latency and the ratio of swimming distance in platform quadrant to total swimming distance in each group were observed by using Morris water maze, and the PSD-95 protein expression in hippocampal CA 1 was measured by immunohistochemical techniques. Compared with the blank group, the escape latency in the model group and the non-acupoint group lengthened (both P swimming distance in platform quadrant to total swimming distance was decreased (both P swimming distance in platform quadrant to total swimming distance was increased, the PSD-95 protein expression was increased (both P swimming distance in platform quadrant to total swimming distance and the PSD-95 protein expression had no significant difference between EAGV 1 group and EAGV 20 group (P > 0.05). Electroacupuncture at Changqiang (GV 1) or Baihui (GV 20) can respectively improve learning and memory ability of rats with autism, which has no significant difference and the mechanism of action may be

  17. Room acoustics for the aged.

    Science.gov (United States)

    Plomp, R; Duquesnoy, A J

    1980-12-01

    This article deals with the combined effects of noise and reverberation on the speech-reception threshold for sentences. It is based on a series of current investigations on: (1) the modulation-transfer function as a measure of speech intelligibility in rooms, (2) the applicability of this concept to hearing-impaired persons, and (3) hearing loss for speech in quiet and in noise as a function of age. It is shown that, generally, in auditoria, classrooms, etc. the reverberation time T, acceptable for normal-hearing listeners, has to be reduced to (0.75)DT in order to be acceptable for elderly subjects with a hearing loss of D dB for speech in noise; for listening conditions as in lounges, restaurants, etc. the corresponding value is (0.82)DT.

  18. Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography.

    Science.gov (United States)

    Li, Yan; Chamberlain, Winston; Tan, Ou; Brass, Robert; Weiss, Jack L; Huang, David

    2016-02-01

    To screen for subclinical keratoconus by analyzing corneal, epithelial, and stromal thickness map patterns with Fourier-domain optical coherence tomography (OCT). Four centers in the United States. Cross-sectional observational study. Eyes of normal subjects, subclinical keratoconus eyes, and the topographically normal eye of a unilateral keratoconus patient were studied. Corneas were scanned using a 26,000 Hz Fourier-domain OCT system (RTVue). Normal subjects were divided into training and evaluation groups. Corneal, epithelial, and stromal thickness maps and derived diagnostic indices, including pattern standard deviation (PSD) variables and pachymetric map-based keratoconus risk scores, were calculated from the OCT data. Area under the receiver operating characteristic curve (AUC) analysis was used to evaluate the diagnostic accuracy of the indices. The study comprised 150 eyes of 83 normal subjects, 50 subclinical keratoconus eyes of 32 patients, and 1 topographically normal eye of a unilateral keratoconus patient. Subclinical keratoconus was characterized by inferotemporal thinning of the cornea, epithelium, and stroma. The PSD values for corneal (P keratoconus risk score (AUC = 0.735). High-resolution Fourier-domain OCT could map corneal, epithelial, and stromal thicknesses. Corneal and sublayer thickness changes in subclinical keratoconus could be detected with high accuracy using PSD variables. These new diagnostic variables might be useful in the detection of early keratoconus. Oregon Health and Science University (OHSU) and Drs. Li, Tan, and Huang have a significant financial interest in Optovue, Inc. These potential conflicts have been reviewed and managed by OHSU. Dr. Brass receives research grants from Optovue, Inc. Drs. Chamberlain and Weiss have no financial or proprietary interest in any material or method mentioned. Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  19. From Baltic rooms to conference rooms: my jouney with data

    Science.gov (United States)

    Kozlowski, W. A.

    2015-12-01

    From time spent in murky, mosquito-filled mangrove swamps searching for fiddler crabs, to being transported off ships in webbed "man-baskets" on inky-black winter mornings to sample sea ice, to teaching rooms full of students the benefits of information organization, the wonders of science have long shaped my career path. Regardless of surroundings, the driving factor has always been a desire to learn new skills, then try to figure out how to use them to make work easier or more efficient for myself and hopefully others. Somewhere along the way, I've switched from doing it primarily for my "own" research projects, to a focus on helping others with theirs. Like many in this field, my route to a career in data science has influenced how I do my work. Along the way I've carried skills with me but also learned a few things that have made my journey both practical and fun. In this presentation, I'll discuss a few key factors that contribute to my current efforts as a data curation specialist in a research library, including communication (translation of "library" concepts to "science" concepts and vice versa), flexibility (ability to accomodate ideas, pace and values of those I'm working with), and prioritization (learning to balance what's valuable to researchers with principles important to libraries, curators, repositories, archives and other groups with which I interact).

  20. Predicting Reverberant Room-to-Room Radio Channel by Using Graphs and Rays in Combination

    DEFF Research Database (Denmark)

    Miao, Yang; Pedersen, Troels; Gan, Mingming

    This paper proposes a hybrid modeling approach for prediction of the room-to-room radio propagation channel. The model combines ray tracing with propagation graph. The propagation graph vertices are obtained at each room by ray tracing with the assumption that the receive antenna (or transmit...... and being compared with the measured data. The results show that the proposed modeling works with the simplest parameter settings, i.e. assuming no propagation from room containing receive antenna to room containing transmit antenna, ray tracing applied separately in each room only involves mechanism...

  1. Employment of Molecularly Imprinted Polymers to High-Throughput Screen nNOS-PSD-95 Interruptions: Structure and Dynamics Investigations on Monomer-Template Complexation.

    Science.gov (United States)

    Wang, Yongwei; Zhao, Ting; Dai, Peng; Jiang, Nan; Li, Fei

    2016-03-16

    Molecularly imprinted polymers (MIPs) are employed to screen nNOS-PSD-95 (neuronal nitric oxide synthase post-synaptic density protein-95) interruptions. 5-(3,5-Dichloro-2-hydroxybenzylamino)-2-hydroxybenzoic acid (ZL006; a potential drug candidate for the treatment of stroke, depression, and pain) is employed as a template. Four kinds of functional monomers (2-VP: 2-vinylpyridine; 4-VP: 4-vinylpyridine; MMA: methyl methacrylate; and MAAM: methacrylamide) are designed, and their complexation with ZL006 in various solvents (methanol, acetonitrile, toluene, chloroform) is investigated by molecular dynamics simulations and quantum mechanics calculations. Both 4-VP and MAAM have stronger interactions with ZL006 than those of 2-VP and MMA. The appropriate ratio of monomer to template is 3:1. Intermolecular hydrogen bonds play a dominant role in monomer-template complexation. Ideal solvents are toluene and chloroform, and the solvation effect on monomer-template complexation is revealed. Both molecular modeling and adsorption experiments demonstrate that as-synthesized ZL006-MIP with 4-VP as a monomer has better selectivity than that employing MAAM to screen for nNOS-PSD-95 interruptions. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Question Mapping

    Science.gov (United States)

    Martin, Josh

    2012-01-01

    After accepting the principal position at Farmersville (TX) Junior High, the author decided to increase instructional rigor through question mapping because of the success he saw using this instructional practice at his prior campus. Teachers are the number one influence on student achievement (Marzano, 2003), so question mapping provides a…

  3. Causal mapping

    DEFF Research Database (Denmark)

    Rasmussen, Lauge Baungaard

    2006-01-01

    The lecture note explains how to use the causal mapping method as well as the theoretical framework aoosciated to the method......The lecture note explains how to use the causal mapping method as well as the theoretical framework aoosciated to the method...

  4. Comparison of Microbial Contamination Levels Among Hospital Operating Rooms and Industrial Clean Rooms

    Science.gov (United States)

    Favero, Martin S.; Puleo, John R.; Marshall, James H.; Oxborrow, Gordon S.

    1968-01-01

    Microbial contamination in industrial clean rooms was compared quantitatively and qualitatively with that of hospital operating rooms. The number of aerobic mesophilic microorganisms which accumulated on stainless-steel strips exposed for periods up to 21 weeks to the intramural air of four operating rooms was at least 1 log higher than the accumulation on strips exposed in four clean rooms, and was essentially the same as that found in two factory areas. Volumetric air samplings showed that there were significantly higher numbers of airborne viable particles per cubic foot of air in operating rooms than in industrial clean rooms. In contrast to clean rooms, where most of the airborne contaminants were those associated with human hair, skin, and respiratory tract, the hospital operating rooms showed a very high level of microorganisms associated with dust and soil. Images Fig. 4 PMID:5649862

  5. Increasing operating room efficiency through parallel processing.

    Science.gov (United States)

    Friedman, David M; Sokal, Suzanne M; Chang, Yuchiao; Berger, David L

    2006-01-01

    Because of rising costs and shrinking reimbursements, hospitals must continually find ways to improve efficiency and productivity. This study attempts to increase caseloads in ambulatory surgery operating rooms while maintaining patient satisfaction and safety. In most hospitals, patients move through their operative day in a linear fashion, starting at registration and finishing in the recovery room. Given this pattern, only 1 patient may occupy the efforts of the operating room team at a time. By processing patients in a parallel fashion, operating room efficiency and patient throughput are increased while costs remain stable. Patients undergoing hernia repairs under local anesthesia with intravenous sedation were divided into a control group and an experimental group. Patients in the control group received their local anesthesia in the operating room at the start of the surgery. The experimental group patients received their local anesthesia in the induction room by the surgeon while the operating room was being cleaned and set up. While operative time for the control group and the experimental group were nearly identical, the turnover time and the induction time were significantly shorter for the experimental group. The cumulative reduction in time during the operative day was sufficient to allow the addition of new operative cases. This study demonstrates a system of increasing operating room efficiency by changing patient flow rather than simply working to streamline existing steps. This increase in efficiency is not associated with the expansion of hospital budgets or a decrease in patient safety or satisfaction.

  6. Recovery room nurses' knowledge regarding postoperative airway ...

    African Journals Online (AJOL)

    Background: Recovery room nurses should have the knowledge and skill to identify and manage postoperative airway emergencies in adult patients. Aim: To determine the knowledge of recovery room nurses regarding postoperative airway emergencies in adult patients in private hospitals in Northern Gauteng. Methods: A ...

  7. 32 CFR 701.35 - Reading room.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Reading room. 701.35 Section 701.35 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... DOCUMENTS AFFECTING THE PUBLIC FOIA Definitions and Terms § 701.35 Reading room. Location where (a)(2...

  8. The One-Room Schoolhouse Revisited.

    Science.gov (United States)

    Miller, Elaine Pouletsos

    1979-01-01

    Though their physical settings are different, students in open classrooms share much in common with their predecessors in one-room schoolhouses. The most striking similarity between the open classroom and the one-room schoolhouse is in the flexible student teacher relationships and intimacy and mutual support among students. (Author/GC)

  9. PASSWORD: Organizing Exits from the Resource Room.

    Science.gov (United States)

    Johnson, Linda K.

    1990-01-01

    The article offers a classroom management technique, PASSWORD, that facilitates the smooth transition of handicapped students from the resource room to the regular class. Students are each asked a "code question," usually a review question, the answer to which is the password for leaving the resource room. (DB)

  10. Simulating People Moving in Displacement Ventilated Rooms

    DEFF Research Database (Denmark)

    Mattsson, M.; Bjørn, Erik; Sandberg, M.

    A displacement ventilation system works better the more uni-directional the air flow through the ventilated room is: from floor to ceiling. Thus, from an air quality point of view, there should be as little vertical mixing of the room air as possible. It is therefore comprehensible that physical...

  11. Evaporation Controlled Emission in Ventilated Rooms

    DEFF Research Database (Denmark)

    Topp, Claus; Nielsen, Peter V.; Heiselberg, Per

    -scale ventilated room when the emission is fully or partly evaporation controlled. The objective of the present research work has been to investigate the change of emission rates from small-scale experiments to full-scale ventilated rooms and to investigate the influence of the local air velocity field near...

  12. Reliability of estimating the room volume from a single room impulse response

    NARCIS (Netherlands)

    Kuster, M.

    2008-01-01

    The methods investigated for the room volume estimation are based on geometrical acoustics, eigenmode, and diffuse field models and no data other than the room impulse response are available. The measurements include several receiver positions in a total of 12 rooms of vastly different sizes and

  13. Three-dimensional point-cloud room model for room acoustics simulations

    DEFF Research Database (Denmark)

    Markovic, Milos; Olesen, Søren Krarup; Hammershøi, Dorte

    2013-01-01

    acquisition and its representation with a 3D point-cloud model, as well as utilization of such a model for the room acoustics simulations. A room is scanned with a commercially available input device (Kinect for Xbox360) in two different ways; the first one involves the device placed in the middle of the room...

  14. Three-dimensional point-cloud room model in room acoustics simulations

    DEFF Research Database (Denmark)

    Markovic, Milos; Olesen, Søren Krarup; Hammershøi, Dorte

    2013-01-01

    acquisition and its representation with a 3D point-cloud model, as well as utilization of such a model for the room acoustics simulations. A room is scanned with a commercially available input device (Kinect for Xbox360) in two different ways; the first one involves the device placed in the middle of the room...

  15. High Efficiency Room Air Conditioner

    Energy Technology Data Exchange (ETDEWEB)

    Bansal, Pradeep [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-01-01

    This project was undertaken as a CRADA project between UT-Battelle and Geberal Electric Company and was funded by Department of Energy to design and develop of a high efficiency room air conditioner. A number of novel elements were investigated to improve the energy efficiency of a state-of-the-art WAC with base capacity of 10,000 BTU/h. One of the major modifications was made by downgrading its capacity from 10,000 BTU/hr to 8,000 BTU/hr by replacing the original compressor with a lower capacity (8,000 BTU/hr) but high efficiency compressor having an EER of 9.7 as compared with 9.3 of the original compressor. However, all heat exchangers from the original unit were retained to provide higher EER. The other subsequent major modifications included- (i) the AC fan motor was replaced by a brushless high efficiency ECM motor along with its fan housing, (ii) the capillary tube was replaced with a needle valve to better control the refrigerant flow and refrigerant set points, and (iii) the unit was tested with a drop-in environmentally friendly binary mixture of R32 (90% molar concentration)/R125 (10% molar concentration). The WAC was tested in the environmental chambers at ORNL as per the design rating conditions of AHAM/ASHRAE (Outdoor- 95F and 40%RH, Indoor- 80F, 51.5%RH). All these modifications resulted in enhancing the EER of the WAC by up to 25%.

  16. Ergonomics in the operating room.

    Science.gov (United States)

    Janki, Shiromani; Mulder, Evalyn E A P; IJzermans, Jan N M; Tran, T C Khe

    2017-06-01

    Since the introduction of minimally invasive surgery, surgeons appear to be experiencing more occupational musculoskeletal injuries. The aim of this study is to investigate the current frequency and effects of occupational musculoskeletal injuries on work absence. An online questionnaire was conducted among all surgeons affiliated to the Dutch Society for Endoscopic Surgery, Gastrointestinal Surgery, and Surgical Oncology. In addition, this survey was conducted among surgeons, gynaecologists, and urologists of one cluster of training hospitals in the Netherlands. There were 127 respondents. Fifty-six surgeons currently suffer from musculoskeletal complaints, and 30 have previously suffered from musculoskeletal complaints with no current complaints. Frequently reported localizations were the neck (39.5 %), the erector spinae muscle (34.9 %), and the right deltoid muscle (18.6 %). Most of the musculoskeletal complaints were present while operating (41.8 %). Currently, 37.5 % uses medication and/or therapy to reduce complaints. Of surgeons with past complaints, 26.7 % required work leave and 40.0 % made intraoperative adjustments. More surgeons with a medical history of musculoskeletal complaints have current complaints (OR 6.1, 95 % CI 1.9-19.6). There were no significant differences between surgeons of different operating techniques in localizations and frequency of complaints, or work leave. Despite previous various ergonomic recommendations in the operating room, the current study demonstrated that musculoskeletal complaints and subsequent work absence are still present among surgeons, especially among surgeons with a positive medical history for musculoskeletal complaints. Even sick leave was necessary to fully recover. There were no significant differences in reported complaints between surgeons of different operating techniques. Almost half of the respondents with complaints made intraoperative ergonomic adjustments to prevent future complaints. The

  17. Perceptual effects in auralization of virtual rooms

    Science.gov (United States)

    Kleiner, Mendel; Larsson, Pontus; Vastfjall, Daniel; Torres, Rendell R.

    2002-05-01

    By using various types of binaural simulation (or ``auralization'') of physical environments, it is now possible to study basic perceptual issues relevant to room acoustics, as well to simulate the acoustic conditions found in concert halls and other auditoria. Binaural simulation of physical spaces in general is also important to virtual reality systems. This presentation will begin with an overview of the issues encountered in the auralization of room and other environments. We will then discuss the influence of various approximations in room modeling, in particular, edge- and surface scattering, on the perceived room response. Finally, we will discuss cross-modal effects, such as the influence of visual cues on the perception of auditory cues, and the influence of cross-modal effects on the judgement of ``perceived presence'' and the rating of room acoustic quality.

  18. Clean Industrial Room for Drift Tube Assembling

    CERN Document Server

    Glonti, GL; Evtoukhovitch, P G; Kroa, G; Manz, A; Potrap, I N; Rihter, P; Stoletov, G D; Tskhadadze, E G; Chepurnov, V F; Chirkov, A V; Shelkov, G A

    2001-01-01

    Description of a clean industrial room for assembly of drift tubes for the muon spectrometer of the ATLAS experiment is presented. High quality specifications on the detectors to be produced demanded creation of a workplace with stable temperature and humidity, as well as minimum quantity of dust in the room. Checking of parameters of intra-room air during long period of continuous work has been confirmed correctness of the designed characteristics of the climatic system installed in the clean room. The room large volum (\\sim 190 m^3), the powerful and flexible climatic system, and simplicity of service allow assembling of detectors with length up to 5 m. Subsequent checking of functionality of the assembled detectors has shown high quality of assembling (the amount of rejected tubes does not exceed 2 %). It demonstrates conformity to the assembling quality requirements for mass production of drift chambers for the muon spectrometer.

  19. Control room philosophy: Principles of control room design and control room work; Kontrollrumsfilosofi: Principer foer kontrollrumsutformning och kontrollrumsarbete

    Energy Technology Data Exchange (ETDEWEB)

    Skriver, Jan; Ramberg, Jasmine; Allwin, Pernilla [Scandpower Risk Management AB, Uppsala (Sweden)

    2006-01-15

    In order to provide insights for improvement of work in control rooms several factors have to be considered. Knowledge of principles including control room philosophies will guide the recommended improvements. In addition to knowledge about specific principles an advantage for an organization can be an understanding of similarities and policies used in other high risk industry. The report has been developed on the basis of a document analysis of international standards and other guiding documents. (NUREG 0711, ISO 11064, ISO 6385, IEC 60964). In addition to the document analysis which has strived to compare the documents to see similarities in important principals, experience from working with control room design, modifications and evaluations in other high risk industries has pervaded the report. Important principles have been identified which are recommended to be included in a control room philosophy. Many of these are similar to the principles identified in the international standards. An additional principal which is regarded as important is the utilization of Key Performance Indicators (KPI) which can be used as a measure to target preventative means. Further more it is critical that the control room philosophy is easy to access and comprehend for all users. One of the challenges that remain after having developed a control room philosophy is how to utilize it in the daily work situation. It is vital that the document remains as a living document, guiding the continual improvement of the control room in the various life cycle stages.

  20. Participatory Maps

    DEFF Research Database (Denmark)

    Salovaara-Moring, Inka

    2016-01-01

    practice. In particular, mapping environmental damage, endangered species, and human-made disasters has become one focal point for environmental knowledge production. This type of digital map has been highlighted as a processual turn in critical cartography, whereas in related computational journalism......, it can be seen as an interactive and iterative process of mapping complex and fragile ecological developments. This article looks at computer-assisted cartography as part of environmental knowledge production. It uses InfoAmazonia, the data-journalism platform on Amazon rainforests, as an example...

  1. Recursive Frame Analysis: A Practitioner's Tool for Mapping Therapeutic Conversation

    Science.gov (United States)

    Keeney, Hillary; Keeney, Bradford; Chenail, Ronald J.

    2012-01-01

    Recursive frame analysis (RFA), both a practical therapeutic tool and an advanced qualitative research method that maps the structure of therapeutic conversation, is introduced with a clinical case vignette. We present and illustrate a means of mapping metaphorical themes that contextualize the performance taking place in the room, recursively…

  2. Prior listening in rooms improves speech intelligibility.

    Science.gov (United States)

    Brandewie, Eugene; Zahorik, Pavel

    2010-07-01

    Although results from previous studies have demonstrated that the acoustic effects of a single reflection are perceptually suppressed after repeated exposure to a particular configuration of source and reflection, the extent to which this dynamic echo suppression might generalize to speech understanding in room environments with multiple reflections and reverberation is largely unknown. Here speech intelligibility was measured using the coordinate response measure corpus both with and without prior listening exposure to a reverberant room environment, which was simulated using virtual auditory space techniques. Prior room listening exposure was manipulated by presenting either a two-sentence carrier phrase that preceded the target speech, or no carrier phrase within the room environment. Results from 14 listeners indicate that with prior room exposure, masked speech reception thresholds were on average 2.7 dB lower than thresholds without exposure, an improvement in intelligibility of over 18 percentage points on average. This effect, which is shown to be absent in anechoic space and greatly reduced under monaural listening conditions, demonstrates that prior binaural exposure to reverberant rooms can improve speech intelligibility, perhaps due to a process of perceptual adaptation to the acoustics of the listening room.

  3. Stability of disposal rooms during waste retrieval

    Energy Technology Data Exchange (ETDEWEB)

    Brandshaug, T.

    1989-03-01

    This report presents the results of a numerical analysis to determine the stability of waste disposal rooms for vertical and horizontal emplacement during the period of waste retrieval. It is assumed that waste retrieval starts 50 years after the initial emplacement of the waste, and that access to and retrieval of the waste containers take place through the disposal rooms. It is further assumed that the disposal rooms are not back-filled. Convective cooling of the disposal rooms in preparation for waste retrieval is included in the analysis. Conditions and parameters used were taken from the Nevada Nuclear Waste Storage Investigation (NNWSI) Project Site Characterization Plan Conceptual Design Report (MacDougall et al., 1987). Thermal results are presented which illustrate the heat transfer response of the rock adjacent to the disposal rooms. Mechanical results are presented which illustrate the predicted distribution of stress, joint slip, and room deformations for the period of time investigated. Under the assumption that the host rock can be classified as ``fair to good`` using the Geomechanics Classification System (Bieniawski, 1974), only light ground support would appear to be necessary for the disposal rooms to remain stable. 23 refs., 28 figs., 2 tabs.

  4. Working in operating rooms, an unhealthy existance?

    Science.gov (United States)

    Rejger, V; Burm, A G; Spierdijk, J

    1975-01-01

    A literature survey indicates that some complaints occur relatively frequently among anesthetists and nurses working in operating rooms. Pollution of the air in the operating rooms by anesthetic gases is often considered as a possible cause. On account of this the degree of pollution has been determined. Concentrations of nitrous oxide and halothane were measured using an infrared absorption spectrophotometer. In each room the concentrations were measured at several different sites. In naturally ventilated operating rooms the concentrations increased steadily during operation. The measured values lied mostly between 1500 and 3000 ppm (vol/vol) for nitrous oxide and between 15 and 35 ppm for halothane. In mechanically ventilated operating rooms where no recirculation is applied a constant level was found some time after the beginning of an operation. The concentrations varied from about 100 to 500 ppm for nitrous oxide and from 1 to 5 ppm for halothane. In naturally ventilated operating rooms the anesthetic gases were rather homogeneously spread, while in mechanically ventilated rooms there was an inhomogeneous distribution. Scavenging of waste anesthetics is recommended.

  5. Human LRRK2 G2019S mutation represses post-synaptic protein PSD95 and causes cognitive impairment in transgenic mice.

    Science.gov (United States)

    Adeosun, Samuel O; Hou, Xu; Zheng, Baoying; Melrose, Heather L; Mosley, Thomas; Wang, Jun Ming

    2017-07-01

    LRRK2 G2019S mutation is associated with increased kinase activity and is the most common mutation associated with late-onset PD. However, the transgenic mouse model has not recapitulated cardinal PD-related motor phenotypes. Non-motor symptoms of PD including cognitive impairments are very common and may appear earlier than the motor symptoms. The objective of this study was to determine whether human LRRK2 with G2019S mutation causes hippocampus-dependent cognitive deficits in mice. Male (LRRK2-G2019S) LRRK2-Tg mice showed impairments in the early portion of the Two-day radial arm water maze acquisition trial as well as in the reversal learning on the third day. However, their performance was similar to Non-Tg controls in the probe trial. LRRK2-Tg mice also displayed impairments in the novel arm discrimination test but not in the spontaneous alternation test in Y-maze. Interestingly, there was no statistically significant locomotor impairment during any of these cognitive test, nor in the locomotor tests including open field, accelerating rotarod and pole tests. Expression of the postsynaptic protein PSD-95 but not the presynaptic protein synaptophysin was lower in hippocampal homogenates of LRRK2-Tg mice. Consistent with previous reports in human LRRK2 G2019S carriers, the current data suggests that cognitive dysfunctions are present in LRRK2-Tg mice even in the absence of locomotor impairment. LRRK2 G2019S mutation represses the postsynaptic protein PSD-95 but not the presynaptic protein synaptophysin. This study also suggests that mild cognitive impairment may appear earlier than motor dysfunctions in LRRK2-G2019S mutation carriers. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Dose-mapping distribution around MNSR

    CERN Document Server

    Jamal, M H

    2002-01-01

    The aim of this study is to establish the dose-rate map through the determination of radiological dose-rate levels in reactor hall, adjacent rooms, and outside the MNSR facility. Controlling dose rate to reactor operating personnel , dose map was established. The map covers time and distances in the reactor hall, during reactor operation at nominal power. Different measurement of dose rates in other areas of the reactor buildings was established. The maximum dose rate, during normal operation of the MNSR was 40 and 21 Sv/hr on the top of the reactor and near the pool fence, respectively. Whereas, gamma and neutron doses have not exceeded natural background in all rooms adjacent to the reactor hall or nearly buildings. The relation between the dose rate for gamma rays and neutron flux at the top of cover of reactor pool was studied as well. It was found that this relation is linear.

  7. Simultaneous Localization and Mapping in Multipath Environments: Mapping and Reusing of Virtual Transmitters

    OpenAIRE

    Gentner, Christian; Ma, Boxiao; Pöhlmann, Robert; Jost, Thomas; Dammann, Armin

    2016-01-01

    Channel-SLAM is an algorithm which uses multipath propagation for positioning and treats multipath components (MPCs) as line-of-sight (LoS) signals originated from virtual transmitters (VTs). To use the information of the MPCs, Channel-SLAM estimates the receiver position and the position of the VTs simultaneously using simultaneous localization and mapping (SLAM) and does not require any prior information such as room-layout or a database for fingerprinting. This paper investigates mapping, ...

  8. Walkable self-overlapping virtual reality maze and map visualization demo: public virtual reality setup for asymmetric collaboration

    DEFF Research Database (Denmark)

    Serubugo, Sule; Skantarova, Denisa; Evers, Nicolaj

    2017-01-01

    This paper describes our demonstration of a walkable self-overlapping maze and its corresponding map to facilitate asymmetric collaboration for room-scale virtual reality setups in public places.......This paper describes our demonstration of a walkable self-overlapping maze and its corresponding map to facilitate asymmetric collaboration for room-scale virtual reality setups in public places....

  9. SRF Clean Rooms and Cryomodule Assembly

    Data.gov (United States)

    Federal Laboratory Consortium — Three primary cleanroom facilities used for the SRF cryomodule production program are available. All 3 clean rooms have class 10 and class 100 areas. The largest is...

  10. Room temperature creep in metals and alloys

    Energy Technology Data Exchange (ETDEWEB)

    Deibler, Lisa Anne [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Materials Characterization and Performance

    2014-09-01

    Time dependent deformation in the form of creep and stress relaxation is not often considered a factor when designing structural alloy parts for use at room temperature. However, creep and stress relaxation do occur at room temperature (0.09-0.21 Tm for alloys in this report) in structural alloys. This report will summarize the available literature on room temperature creep, present creep data collected on various structural alloys, and finally compare the acquired data to equations used in the literature to model creep behavior. Based on evidence from the literature and fitting of various equations, the mechanism which causes room temperature creep is found to include dislocation generation as well as exhaustion.

  11. When to use the emergency room - child

    Science.gov (United States)

    Emergency room - child; Emergency department - child; Urgent care - child; ER - when to use ... How quickly does your child need care? If your child could die or be permanently disabled, it is an emergency. Call 911 to have the ...

  12. Virtual Training of Compressor Control Room Project

    Data.gov (United States)

    National Aeronautics and Space Administration — MYMIC will analyze, design, develop and evaluate the Virtual Control Room – Compressor Station (VCoR-CS) training system. VCoR-CS will provide procedural...

  13. MEMS and Nano-Technology Clean Room

    Data.gov (United States)

    Federal Laboratory Consortium — The MEMS and Nano-Technology Clean Room is a state-of-the-art, 800 square foot, Class 1000-capable facility used for development of micro and sub-micro scale sensors...

  14. Microalgal Mass Culture Room Harvest Records

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The microalgal mass culture room, housed at the NOAA Fisheries' Milford CT laboratory, provides research grade microalgae (phytoplankton) to in-house and...

  15. Binaural prediction of speech intelligibility in reverberant rooms with multiple noise sources.

    Science.gov (United States)

    Lavandier, Mathieu; Jelfs, Sam; Culling, John F; Watkins, Anthony J; Raimond, Andrew P; Makin, Simon J

    2012-01-01

    When speech is in competition with interfering sources in rooms, monaural indicators of intelligibility fail to take account of the listener's abilities to separate target speech from interfering sounds using the binaural system. In order to incorporate these segregation abilities and their susceptibility to reverberation, Lavandier and Culling [J. Acoust. Soc. Am. 127, 387-399 (2010)] proposed a model which combines effects of better-ear listening and binaural unmasking. A computationally efficient version of this model is evaluated here under more realistic conditions that include head shadow, multiple stationary noise sources, and real-room acoustics. Three experiments are presented in which speech reception thresholds were measured in the presence of one to three interferers using real-room listening over headphones, simulated by convolving anechoic stimuli with binaural room impulse-responses measured with dummy-head transducers in five rooms. Without fitting any parameter of the model, there was close correspondence between measured and predicted differences in threshold across all tested conditions. The model's components of better-ear listening and binaural unmasking were validated both in isolation and in combination. The computational efficiency of this prediction method allows the generation of complex "intelligibility maps" from room designs. © 2012 Acoustical Society of America.

  16. The Advanced Photon Source main control room

    Energy Technology Data Exchange (ETDEWEB)

    Pasky, S.

    1998-07-01

    The Advanced Photon Source at Argonne National Laboratory is a third-generation light source built in the 1990s. Like the machine itself, the Main Control Room (MCR) employs design concepts based on today`s requirements. The discussion will center on ideas used in the design of the MCR, the comfort of personnel using the design, and safety concerns integrated into the control room layout.

  17. CALS Mapping

    DEFF Research Database (Denmark)

    Collin, Ib; Nielsen, Povl Holm; Larsen, Michael Holm

    1998-01-01

    To enhance the industrial applications of CALS, CALS Center Danmark has developed a cost efficient and transparent assessment, CALS Mapping, to uncover the potential of CALS - primarily dedicated to small and medium sized enterprises. The idea behind CALS Mapping is that the CALS State...... of the enterprise is compared with a Reference Enterprise Model (REM). The REM is a CALS idealised enterprise providing full product support throughout the extended enterprise and containing different manufacturing aspects, e.g. component industry, process industry, and one-piece production. This CALS idealised...... enterprise is, when applied in a given organisation modified with respect to the industry regarded, hence irrelevant measure parameters are eliminated to avoid redundancy. This assessment of CALS Mapping, quantify the CALS potential of an organisation with the purpose of providing decision support to the top...

  18. Real-time virtual room acoustic simulation

    Science.gov (United States)

    Carneal, James P.; Johnson, Jan; Johnson, Troge; Johnson, Marty

    2003-10-01

    A realistic virtual room acoustic simulation has been implemented on a PC-based computer in near real-time. Room acoustics are calculated by the image source method using realistic absorption coefficients for a variety of realistic surfaces and programmed in MATLAB. The resulting impulse response filters are then applied in near real-time using fast convolution DSP techniques using data being read from a CD-ROM. The system was implemented in a virtual acoustic room facility. Optimizations have been performed to retain the realistic virtual room effect while minimizing computations through limited psycho-acoustic testing. In general, realistic anechoic to reverberant virtual rooms have been re-created with six 8192 coefficient filters. To provide realistic simulations, special care must be taken to accurately reproduce the low frequency acoustics. Since the virtual room acoustic facility was not totally anechoic (as are most anechoic chambers), inverse filters were applied to compensate for over-amplified acoustics at frequencies below 350 Hz.

  19. Physics escape room as an educational tool

    Science.gov (United States)

    Vörös, Alpár István Vita; Sárközi, Zsuzsa

    2017-12-01

    Escape rooms have flourished in the last decade. These are adventure games in which players work together to solve puzzles using hints, clues and a strategy to escape from a locked room. In many cases they use different phenomena related to physics. Hence the idea of using escape rooms in science centers or even in classroom activities. Escape rooms are designed for one single team of players, the method is more suitable for activities in a science centre. In our paper, we show that escape rooms' puzzle solving methods could be used in physics classroom activities as well, taking into account that several teams have to work together in the same room/place. We have developed an educational escape game for physics of fluids, as this topic is left out from the Romanian high-school curriculum. We have tried out our game during the project week called "Şcoala altfel" ("school in a different way") and in a physics camp for gifted students. We present the designed physics escape game and the results.

  20. Clinic exam room design: present and future.

    Science.gov (United States)

    Freihoefer, Kara; Nyberg, Gary; Vickery, Christine

    2013-01-01

    This article aims to deconstruct various design qualities and strategies of clinic exam rooms, and discuss how they influence users' interaction and behavior in the space. Relevant literature supports the advantages and disadvantages of different design strategies. Annotated exam room prototypes illustrate the design qualities and strategies discussed. Advancements in technology and medicine, along with new legislative policies, are influencing the way care providers deliver care and ultimately clinic exam room designs. The patient-centered medical home model has encouraged primary care providers to make patients more active leaders of their health plan which will influence the overall functionality and configuration of clinic exam rooms. Specific design qualities discussed include overall size, location of doors and privacy curtains, positioning of exam tables, influence of technology in the consultation area, types of seating, and placement of sink and hand sanitizing dispensers. In addition, future trends of exam room prototypes are presented. There is a general lack of published evidence to support design professionals' design solutions for outpatient exam rooms. Future research should investigate such topics as the location of exam tables and privacy curtains as they relate to patient privacy; typical size and location of consultation table as it relates to patient connection and communication; and placement of sinks and sanitization dispensers as they relate to frequency and patterns of usage. Literature review, outpatient, technology, visual privacy.

  1. Cognitive maps

    DEFF Research Database (Denmark)

    Minder, Bettina; Laursen, Linda Nhu; Lassen, Astrid Heidemann

    2014-01-01

    . Conceptual clustering is used to analyse and order information according to concepts or variables from within the data. The cognitive maps identified are validated through the comments of some of the same experts. The study presents three cognitive maps and respective world-views explaining how the design...... and innovation field are related and under which dimensions they differ. The paper draws preliminary conclusions on the implications of the different world- views on the innovation process. With the growing importance of the design approach in innovation e.g. design thinking, a clear conception...

  2. Participatory maps

    DEFF Research Database (Denmark)

    Salovaara-Moring, Inka

    towards a new political ecology. This type of digital cartographies has been highlighted as the ‘processual turn’ in critical cartography, whereas in related computational journalism it can be seen as an interactive and iterative process of mapping complex and fragile ecological developments. This paper...... looks at computer-assisted cartography as part of environmental knowledge production. It uses InfoAmazonia, the databased platform on Amazon rainforests, as an example of affective geo-visualization within information mapping that enhances embodiment in the experience of the information. Amazonia...

  3. Using acoustic information to perceive room size: effects of blindness, room reverberation time, and stimulus.

    Science.gov (United States)

    Kolarik, Andrew J; Pardhan, Shahina; Cirstea, Silvia; Moore, Brian C J

    2013-01-01

    Blind participants greatly rely on sound for spatial information regarding the surrounding environment. It is not yet established whether lack of vision to calibrate audition in far space affects blind participants' internal spatial representation of acoustic room size. Furthermore, blind participants may rely more on farthest distance estimates to sound sources compared with sighted participants when perceiving room size. Here we show that judgments of apparent room size and sound distance are correlated, more so for blind than for sighted participants. Sighted participants judged a reverberant virtual room to be larger for speech than for music or noise stimuli, whereas blind participants did not. The results suggest that blindness affects the use of room reverberation for distance and room-size judgments.

  4. The uncertainty room: strategies for managing uncertainty in a surgical waiting room.

    Science.gov (United States)

    Stone, Anne M; Lammers, John C

    2012-01-01

    To describe experiences of uncertainty and management strategies for staff working with families in a hospital waiting room. A 288-bed, nonprofit community hospital in a Midwestern city. Data were collected during individual, semistructured interviews with 3 volunteers, 3 technical staff members, and 1 circulating nurse (n = 7), and during 40 hours of observation in a surgical waiting room. Interview transcripts were analyzed using constant comparative techniques. The surgical waiting room represents the intersection of several sources of uncertainty that families experience. Findings also illustrate the ways in which staff manage the uncertainty of families in the waiting room by communicating support. Staff in surgical waiting rooms are responsible for managing family members' uncertainty related to insufficient information. Practically, this study provided some evidence that staff are expected to help manage the uncertainty that is typical in a surgical waiting room, further highlighting the important role of communication in improving family members' experiences.

  5. Perceptual Optimization of Room-In-Room Reproduction with Spatially Distributed Loudspeakers

    OpenAIRE

    Grosse, Julian; van de Par, Steven

    2014-01-01

    It is often desirable to reproduce a specific room-acoustic scene, e.g. a concert hall in a playback room, in such a way that the listener has a plausible and authentic spatial impression of the original sound source including the room acoustical properties. In this study a perceptually motivated approach for spatial audio reproduction is developed. This approach optimizes the spatial and monaural cues of the direct and reverberant sound separately. More specifically, the (monaural) spectral ...

  6. Human Computer Interaction in the ALMA Control Room

    Science.gov (United States)

    Schilling, M.; Primet, R.; Pietriga, E.; Schwarz, J.

    2012-09-01

    The article describes the ALMA Operations Monitoring and Control (OMC) software and its next generation user interfaces, used by operators and astronomers to monitor and control the observing facility. These user interfaces bring state-of-the-art Human Computer Interaction (HCI) techniques to the ALMA Control Room: map visualisation, semantic zooming, navigation gestures, multiple coordinated views, and decrease of time-to-point. They enable users to stay in control of dozens of antennas, hundreds of devices, and thousands of baselines. The Atacama Large Millimeter/submillimeter Array (ALMA), an international radio-astronomy facility, is a partnership of North America, Europe and East Asia in cooperation with the Republic of Chile. It is located at the Altiplano de Chajnantor and is being operated from the Operations Support Facilities (OSF) near San Pedro de Atacama.

  7. Method for Pre-Conditioning a Measured Surface Height Map for Model Validation

    Science.gov (United States)

    Sidick, Erkin

    2012-01-01

    eliminate the surface measurement noise or measurement errors can also suffer from aliasing effects. During re-sampling of a surface map, this software preserves the low spatial-frequency characteristic of a given surface map through the use of Zernike-polynomial fit coefficients, and maintains mid- and high-spatial-frequency characteristics of the given surface map by the use of a PSD model derived from the two-dimensional PSD data of the mid- and high-spatial-frequency components of the original surface map. Because this new method creates the new surface map in the desired sampling format from analytical expressions only, it does not encounter any aliasing effects and does not cause any discontinuity in the resultant surface map.

  8. MAPPING INNOVATION

    DEFF Research Database (Denmark)

    Thuesen, Christian Langhoff; Koch, Christian

    2011-01-01

    trends as globalization. Three niches (Lean Construction, BIM and System Deliveries) are subject to a detailed analysis showing partly incompatible rationales and various degrees of innovation potential. The paper further discusses how existing policymaking operates in a number of tensions one being......, the innovation map can act as a medium in which policymakers, interest organization and companies can develop and coordinate future innovation activities....

  9. Meal mapping

    DEFF Research Database (Denmark)

    Scholderer, Joachim; Kügler, Jens; Olsen, Nina Veflen

    2013-01-01

    probabilities are subjected to multiple correspondence analysis and mapped into low-dimensional space. In a third step, the principal coordinates representing meal centres and side components in the correspondence analysis solution are subjected to cluster analysis to identify distinct groups of compatible...

  10. Mapping filmmaking

    DEFF Research Database (Denmark)

    Gilje, Øystein; Frølunde, Lisbeth; Lindstrand, Fredrik

    2010-01-01

    This chapter concerns mapping patterns in regards to how young filmmakers (age 15 – 20) in the Scandinavian countries learn about filmmaking. To uncover the patterns, we present portraits of four young filmmakers who participated in the Scandinavian research project Making a filmmaker. The focus...

  11. Affective Maps

    DEFF Research Database (Denmark)

    Salovaara-Moring, Inka

    of digital cartographies has been highlighted as the ‘processual turn’ in critical cartography, whereas in related computational journalism it can be seen as an interactive and iterative process of mapping complex and fragile ecological developments. This paper looks at computer-assisted cartography as part...

  12. Role of Magnetocardiography in Emergency Room

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, H.; Kim, K.; Kim, J. M.; Lee, Y. H.; Kim, T. E.; Lim, H. K.; Park, Y. K. [Biomagnetism Research Center, Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of); Ko, Y. G.; Chung, N. [Cardiovascular Center, College of Medicine, Yonsei University, Seoul (Korea, Republic of)

    2006-10-15

    In emergency rooms, patients with acute chest pain should be diagnosed as quickly as possible with higher diagnostic accuracy for an appropriate therapy to the patients with acute coronary syndrome or for avoiding unnecessary hospital admissions. At present, electrocardiography(ECG) and biochemical markers are generally used to detect myocardial infarction and coronary angiography is used as a gold standard to reveal the degree of narrowing of coronary artery. Magnetocardiography(MCG) has been proposed as a novel and non-invasive diagnostic tool fur the detection of cardiac electrical abnormality associated with myocardial ischemia. In this study, we examined whether the MCG can be used fur the detection of coronary artery disease(CAD) in patients, who were admitted to the emergency room with acute chest pain. MCG was recorded from 36 patients admitted to the emergency room with suspected acute coronary syndrome. The MCG recordings were obtained using a 64-channel SQUID MCG system in a magnetically shielded room. In result, presence of CAD could be found with a sensitivity of 88.2 % in patients with acute chest pain without 57 elevation in ECG, demonstrating a possible use in the emergency room to screen CAD patients.

  13. Room acoustics modeling using a point-cloud representation of the room geometry

    DEFF Research Database (Denmark)

    Markovic, Milos; Olesen, Søren Krarup; Hammershøi, Dorte

    2013-01-01

    geometry acquisition is presented. The method exploits a depth sensor of the Kinect device that provides a point based information of a scanned room interior. After post-processing of the Kinect output data, a 3D point-cloud model of the room is obtained. Sound transmission between two selected points...

  14. Improved low frequency room responses by considering finiteness of room boundary surfaces

    DEFF Research Database (Denmark)

    Jeong, Cheol-Ho

    2013-01-01

    For room acoustic simulations, the acoustic characteristics of room boundary surfaces are typically calculated under the assumption that the surfaces are sufficiently large. In this study, a reflection coefficient for finite surfaces is suggested and its performance is assessed through case studi...

  15. Gas explosion in a room with a window and passage to an adjacent room

    Directory of Open Access Journals (Sweden)

    Polandov Yuri

    2016-01-01

    Full Text Available Some publications describe an effect, produced during a physical model experiment, when an adjacent gas-free room influences the gas explosion pressure in a room with a window. The explosion pressure in this case significantly exceeds (2.5 times the explosion pressure in a room without an adjacent room. This result has been confirmed by our studies. Based on other available information about the influence of the ignition point location on the explosion pressure in one room, it was suggested that this could be true for an explosion in two rooms. In our studies we used a test unit with two connected chambers, each having a volume of 1.125 m3. It turned out that this influence of the adjacent volume was not so unambiguous as it was described in those publications. It was found out that the maximum effect of explosion pressure amplification by the adjacent room is achieved, when the igniter is located in the chamber filled with a gas-air mixture in the area between the center of the chamber and the window (maximum amplification by more than 3 times. This effect is lower directly by the window (1.8 times and is practically absent in case of ignition within the area near the passage connecting the chamber with the adjacent room. This suggests that the effect discovered earlier is a special case of the general dependence of the gas explosion pressure in two chambers on the igniter location.

  16. MAPPING INNOVATION

    DEFF Research Database (Denmark)

    Thuesen, Christian Langhoff; Koch, Christian

    2011-01-01

    By adopting a theoretical framework from strategic niche management research (SNM) this paper presents an analysis of the innovation system of the Danish Construction industry. The analysis shows a multifaceted landscape of innovation around an existing regime, built around existing ways of working...... and developed over generations. The regime is challenged from various niches and the socio-technical landscape through trends as globalization. Three niches (Lean Construction, BIM and System Deliveries) are subject to a detailed analysis showing partly incompatible rationales and various degrees of innovation...... potential. The paper further discusses how existing policymaking operates in a number of tensions one being between government and governance. Based on the concepts from SNM the paper introduces an innovation map in order to support the development of meta-governance policymaking. By mapping some...

  17. Assessment of daylight quality in simple rooms

    DEFF Research Database (Denmark)

    Johnsen, Kjeld; Dubois, Marie-Claude; Sørensen, Karl Grau

    The present report documents the results of a study on daylight conditions in simple rooms of residential buildings. The overall objective of the study was to develop a basis for a method for the assessment of daylight quality in a room with simple geometry and window configurations. As a tool...... for the analyses the Radiance Lighting Simulation System was used. A large number of simulations were performed for 3 rooms (window configurations) under overcast, intermediate, and 40-50 sunny sky conditions for each window (7 months, three orientations and for every other hour with direct sun penetration through......-to-horizontal illuminance ratio as well as scale of shadow gave valuable information allowing a detailed description of the three-dimensional geometry of daylight in the space. It should be mentioned however, that there is no universal definition of light quality. The approach of this study was to analyse differences...

  18. Method of Remotely Constructing a Room

    Science.gov (United States)

    Michie, J. D.; De Hart, R. C.

    1971-10-05

    The testing of nuclear devices of high explosive yield has required that cavities of relatively large size be provided at considerable distances below the surface of the earth for the pre-detonation emplacement of the device. The construction of an essentially watertight chamber or room in the cavity is generally required for the actual emplacement of the device. A method is described of constructing such a room deep within the earth by personnel at the surface. A dual wall bladder of a watertight, pliable fabric material is lowered down a shaft into a selected position. The bladder is filled with a concrete grout while a heavy fluid having essentially the same density as the grout is maintained on both sides of the bladder, to facilitate complete deployment of the bladder by the grout to form a room of desired configuration. (10 claims)

  19. Room Airflows with Low Reynolds Number Effects

    DEFF Research Database (Denmark)

    Topp, Claus; Nielsen, Peter V.; Davidson, Lars

    is limited. It has been the objective to investigate the behaviour of a plane isothermal wall jet in a full-scale ventilated room at low Reynolds numbers, i.e. when the flow is not fully turbulent. The results are significantly different from known theory for fully turbulent flows. It was found that the jet......The behaviour of room airflows under fully turbulent conditions is well known both in terms of experiments and, numerical calculations by computational fluid dynamics (CFD). For room airflows where turbulence is not fully developed though, i.e. flows at low Reynolds numbers, the existing knowledge...... constants are a strong function of the Reynolds number up to a level of Reh≈500....

  20. Personal Exposure in Displacement Ventilated Rooms

    DEFF Research Database (Denmark)

    Brohus, Henrik; Nielsen, Peter Vilhelm

    1996-01-01

    in the lower part of the room close to the occupant. A personal exposure model for displacement ventilated rooms is proposed. The model takes the influence of gradients and the human thermal boundary layer into account. Two new quantities describing the interaction between a person and the ventilation......Personal exposure in a displacement ventilated room is examined. The stratified flow and the considerable concentration gradients necessitate an improvement of the widely used fully mixing compartmental approach. The exposure of a seated and a standing person in proportion to the stratification...... height is examined by means of full-scale measurements. A breathing thermal manikin is used to simulate a person. It is found that the flow in the boundary layer around a person is able to a great extent to entrain and transport air from below the breathing zone. In the case of non-passive, heated...

  1. Electric control of magnetism at room temperature.

    Science.gov (United States)

    Wang, Liaoyu; Wang, Dunhui; Cao, Qingqi; Zheng, Yuanxia; Xuan, Haicheng; Gao, Jinlong; Du, Youwei

    2012-01-01

    In the single-phase multiferroics, the coupling between electric polarization (P) and magnetization (M) would enable the magnetoelectric (ME) effect, namely M induced and modulated by E, and conversely P by H. Especially, the manipulation of magnetization by an electric field at room-temperature is of great importance in technological applications, such as new information storage technology, four-state logic device, magnetoelectric sensors, low-power magnetoelectric device and so on. Furthermore, it can reduce power consumption and realize device miniaturization, which is very useful for the practical applications. In an M-type hexaferrite SrCo(2)Ti(2)Fe(8)O(19), large magnetization and electric polarization were observed simultaneously at room-temperature. Moreover, large effect of electric field-controlled magnetization was observed even without magnetic bias field. These results illuminate a promising potential to apply in magnetoelectric devices at room temperature and imply plentiful physics behind them.

  2. A New Control Room for SLAC Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, Roger; Guerra, E.; Stanek, M.; Hoover, Z.Van; Warren, J.; /SLAC

    2012-06-04

    We are planning to construct a new control room at SLAC to unify and improve the operation of the LCLS, SPEAR3, and FACET accelerator facilities, and to provide the space and flexibility needed to support the LCLS-II and proposed new test beam facilities. The existing control rooms for the linac and SPEAR3 have been upgraded in various ways over the last decade, but their basic features have remained unchanged. We propose to build a larger modern Accelerator Control Room (ACR) in the new Research Support Building (RSB) which is currently under construction at SLAC. Shifting the center of control for the accelerator facilities entails both technical and administrative challenges. In this paper, we describe the history, concept, and status of this project.

  3. Material Specific Design for Room Temperature Superconductivity

    Science.gov (United States)

    Isikaku-Ironkwe, O.-Paul; Ofe, Uko; Oriaku, Chijioke; Asiegbu, Dan; Oguzi, Emeka

    2012-02-01

    The transition temperature, Tc, of superconductors has been increased sevenfold from 23K in Nb3Ge to 164K in Hg-1223. A further two-fold increase would get us to above room temperature superconductivity. Studying high temperature superconductors (HTSCs), we have developed a formula that expresses Tc in terms of electronegativity, valence electrons, Ne, atomic number, Z, formula mass and a coupling constant, Ko. We observe an increasing linear relationship between Tc and Ko. Ko also correlates with formula mass and atomic number and the number of atoms in the compound. By our formula, Hg-1223 has Ko = 70. We propose, using our design algorithm, that room temperature superconductivity may be realized in a system with ko = 160; electronegativity = 2.5, Ne/Sqrt Z = 0.8. We proceed to show combinations of oxides and elements that will yield the required parameters for synthesizing reproducible room temperature superconductivity.

  4. An Informationally Structured Room for Robotic Assistance

    Directory of Open Access Journals (Sweden)

    Tokuo Tsuji

    2015-04-01

    Full Text Available The application of assistive technologies for elderly people is one of the most promising and interesting scenarios for intelligent technologies in the present and near future. Moreover, the improvement of the quality of life for the elderly is one of the first priorities in modern countries and societies. In this work, we present an informationally structured room that is aimed at supporting the daily life activities of elderly people. This room integrates different sensor modalities in a natural and non-invasive way inside the environment. The information gathered by the sensors is processed and sent to a centralized management system, which makes it available to a service robot assisting the people. One important restriction of our intelligent room is reducing as much as possible any interference with daily activities. Finally, this paper presents several experiments and situations using our intelligent environment in cooperation with our service robot.

  5. Light and Mediaprojections in Patient Rooms

    DEFF Research Database (Denmark)

    Bonde, Esben Oxholm Skjødt; Nielsen, Stine Maria Louring; Hansen, Ellen Kathrine

    2018-01-01

    New media and lighting technology and new ways to connect and control it has potentials to improve the environment in hospitals with the goal of increasing patient satisfaction. How should such system be designed to do so and how can it be tested? In this paper it is investigated how a specific...... case, an interactive lighting and media system installed in a patient room, can be improved to support a greater experience of patient satisfaction. Through questionnaires given to 14 mothers who have just given birth and their husbands staying in an interactive patient room, the experience of staying...... in the room and the patient satisfaction has been assessed. The results from the questionnaires are hereto combined to data log on how the media system has been used, which additionally leads to a design evaluation for the interactive media system. The results imply several areas that can be improved to meet...

  6. A phase transition close to room temperature in BiFeO3 thin films.

    Science.gov (United States)

    Kreisel, J; Jadhav, P; Chaix-Pluchery, O; Varela, M; Dix, N; Sánchez, F; Fontcuberta, J

    2011-08-31

    BiFeO3 (BFO) multiferroic oxide has a complex phase diagram that can be mapped by using appropriately substrate-induced strain in epitaxial films. By using Raman spectroscopy, we conclusively show that films of the so-called supertetragonal T-BFO phase, stabilized under compressive strain, display a reversible temperature-induced phase transition at about 100 °C, and thus close to room temperature.

  7. A phase transition close to room temperature in BiFeO{sub 3} thin films

    Energy Technology Data Exchange (ETDEWEB)

    Kreisel, J; Jadhav, P; Chaix-Pluchery, O [Laboratoire des Materiaux et du Genie Physique, Grenoble INP, CNRS, Minatec, 3, parvis Louis Neel, 38016 Grenoble (France); Varela, M [Departamento Fisica Aplicada i Optica, Universitat de Barcelona, Carrer MartI i Franques 1. 08028 Campus UAB, Bellaterra 08193 (Spain); Dix, N; Sanchez, F; Fontcuberta, J, E-mail: jens.kreisel@grenoble-inp.fr [Institut de Ciencia de Materials de Barcelona (ICMAB-CSIC), Campus UAB, Bellaterra 08193 (Spain)

    2011-08-31

    BiFeO{sub 3} (BFO) multiferroic oxide has a complex phase diagram that can be mapped by using appropriately substrate-induced strain in epitaxial films. By using Raman spectroscopy, we conclusively show that films of the so-called supertetragonal T-BFO phase, stabilized under compressive strain, display a reversible temperature-induced phase transition at about 100 deg. C, and thus close to room temperature. (fast track communication)

  8. Multi-bed patient room architectural evaluation

    Directory of Open Access Journals (Sweden)

    Evangelia Sklavou

    2016-12-01

    Full Text Available Introduction: Leveraging the physical environment’s merits is crucial in healthcare settings towards fostering sustainable healing conditions. In the future, the need to retrofit hospitals already appears more probable than to build new facilities. In Greece, holistic healthcare architecture has significant potential and room to develop. Aim: The architectural research of multi-bed patient room environment. Method: A sample of multi-bed patient rooms of a Greek hospital was studied per architectural documentation and user evaluation survey. Beyond recording the existing situation and user experience, user group differences and the influence of window proximity were studied. The survey sample was based on convenience and comprised 160 patients and 136 visitors. Statistical analysis was performed in SPSS 20, using chi-square exact tests of independence. The chosen level of significance was p < 0.05. Results: Architectural documentation showed that the building morphology had a positive impact in patient rooms, with regard to sunlight penetration and view. Further solar daylight control was deemed necessary, to facilitate overall environmental comfort conditions. High spatial density and considerable disadvantages of the middle patient bed, compared to the one bedside the window and the one further in the back of the room, were also ascertained. User groups did not evaluate their surroundings significantly different, with the exception of ease of access to the view. Window proximity influenced both patients and visitors in evaluating ease of access to the view and visual discomfort. Patients were further affected on window size evaluation and visitors on view related aspects. Conclusions: Synergy between building form and function contributes in creating holistic sustainable healing environments. User evaluation can deviate from objective documentation. Patients and visitors experienced the patient room in a similar manner. The middle bed was

  9. Spatially extended sound equalization in rectangular rooms

    DEFF Research Database (Denmark)

    Santillan, Arturo Orozco

    2001-01-01

    The results of a theoretical study on global sound equalization in rectangular rooms at low frequencies are presented. The zone where sound equalization can be obtained is a continuous three-dimensional region that occupies almost the complete volume of the room. It is proved that the equalization...... of broadband signals can be achieved by the simulation of a traveling plane wave using FIR filters. The optimal solution has been calculated following the traditional least-squares approximation, where a modeling delay has been applied to minimize reverberation. An advantage of the method is that the sound...

  10. Dynamics of Glass Relaxation at Room Temperature

    Science.gov (United States)

    Welch, Roger C.; Smith, John R.; Potuzak, Marcel; Guo, Xiaoju; Bowden, Bradley F.; Kiczenski, T. J.; Allan, Douglas C.; King, Ellyn A.; Ellison, Adam J.; Mauro, John C.

    2013-06-01

    The problem of glass relaxation under ambient conditions has intrigued scientists and the general public for centuries, most notably in the legend of flowing cathedral glass windows. Here we report quantitative measurement of glass relaxation at room temperature. We find that Corning® Gorilla® Glass shows measurable and reproducible relaxation at room temperature. Remarkably, this relaxation follows a stretched exponential decay rather than simple exponential relaxation, and the value of the stretching exponent (β=3/7) follows a theoretical prediction made by Phillips for homogeneous glasses.

  11. Spatially extended sound equalization in rectangular rooms

    DEFF Research Database (Denmark)

    Santillan, Arturo Orozco

    2001-01-01

    of broadband signals can be achieved by the simulation of a traveling plane wave using FIR filters. The optimal solution has been calculated following the traditional least-squares approximation, where a modeling delay has been applied to minimize reverberation. An advantage of the method is that the sound......The results of a theoretical study on global sound equalization in rectangular rooms at low frequencies are presented. The zone where sound equalization can be obtained is a continuous three-dimensional region that occupies almost the complete volume of the room. It is proved that the equalization...

  12. [Considerations on a room for leave taking].

    Science.gov (United States)

    Drlicek, M; Kraml, P

    2006-05-01

    Many patients die in hospitals and care centers. It is therefore necessary to create an environment for the dying person, as well as for relatives, which allows death to occur with dignity while also permitting a dignified farewell. A special room should be available for taking leave of the loved one and for the mourning of the relatives. This room should, as far as possible, be neutrally decorated while at the same time it should be appropriate for various cultures and religious requirements. In order to be able to take leave symbolically, it is necessary to place the departed in the light, for example from a window.

  13. Concentration Distribution in a Mixing Ventilated Room

    DEFF Research Database (Denmark)

    Jensen, Rasmus Lund; Pedersen, D.N.; Nielsen, Peter V.

    2001-01-01

    Today there is an increasing focus on the importance of a proper ventilation system to obtain good working conditions in the term of air and thermal quality to ensure high productivity. Different ventilation principles are used, e.g., mixing ventilation and displacement ventilation. In order...... that the air is fully mixed. The objective of this work is to determine the influence of the location of a pollutant, temperature differences and whether the room is furnished or not. It is also investigated if it is sufficient to determine the mean concentration in the room to determine the personal exposure...

  14. 18 CFR 1301.2 - Public reading rooms.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Public reading rooms... Freedom of Information Act § 1301.2 Public reading rooms. TVA maintains a public electronic reading room through its Web site at http://www.tva.gov. This electronic reading room contains the records that the...

  15. 45 CFR 612.2 - Public reading room.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Public reading room. 612.2 Section 612.2 Public... RECORDS AND INFORMATION § 612.2 Public reading room. (a) The Foundation maintains a public reading room... reading room records. (b) Information about FOIA and Privacy at NSF and copies of frequently requested...

  16. 45 CFR 1602.5 - Public reading room.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Public reading room. 1602.5 Section 1602.5 Public... DISCLOSURE OF INFORMATION UNDER THE FREEDOM OF INFORMATION ACT § 1602.5 Public reading room. (a) The Corporation will maintain a public reading room its office at 3333 K St. NW., Washington, DC, 20007. This room...

  17. 22 CFR 303.5 - Public reading room.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Public reading room. 303.5 Section 303.5 Foreign... Public reading room. (a) The Peace Corps will maintain a public reading room at its headquarters at 1111... records will be made available in the public reading room: (1) All final public opinions, including...

  18. 13 CFR 102.2 - Public reading rooms.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Public reading rooms. 102.2... Disclosure of Information § 102.2 Public reading rooms. (a) SBA maintains a public reading room in the... described in paragraph (a) of this section are available in the SBA Online Reading Room at http://www.sba...

  19. 19 CFR 103.1 - Public reading rooms.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Public reading rooms. 103.1 Section 103.1 Customs... reading rooms. Each office listed below will maintain a public reading room or public reading area where... Angeles Street, Los Angeles, California 90012. The reading rooms are open to the public during regular...

  20. 22 CFR 171.3 - Public reading room.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Public reading room. 171.3 Section 171.3... PUBLIC General Policy and Procedures § 171.3 Public reading room. A reading room providing public access..., NW., Washington, DC. The reading room contains material pertaining to access to information under the...

  1. The radiation dose dilemma in the hybrid operating room

    NARCIS (Netherlands)

    de Ruiter, QMB|info:eu-repo/dai/nl/413971171

    2016-01-01

    The of the hybrid Operation room (an operation room combined with advanced radiological X-ray equipment) is gaining popularity, as it is now the preferred room to perform (complex) endovascular aortic procedures. The fixed C-arms equipped in these rooms make it possible to gain very high image

  2. Increase in voice level and speaker comfort in lecture rooms

    DEFF Research Database (Denmark)

    Brunskog, Jonas; Gade, Anders Christian; Bellester, Gaspar Payá

    2009-01-01

    Teachers often suffer from health problems related to their voice. These problems are related to their working environment, including the acoustics of the lecture rooms. However, there is a lack of studies linking the room acoustic parameters to the voice produced by the speaker. In this pilot...... study, the main goals are to investigate whether objectively measurable parameters of the rooms can be related to an increase in the voice sound power produced by speakers and to the speakers’ subjective judgments about the rooms. In six different rooms with different sizes, reverberation times...... that in different rooms significant changes in the sound power produced by the speaker can be found. It is also found that these changes mainly have to do with the size of the room and to the gain produced by the room. To describe this quality, a new room acoustic quantity called “room gain” is proposed....

  3. 77 FR 20355 - Proposed Information Collection; Comment Request; Award Amendment Requests and Project Service Maps

    Science.gov (United States)

    2012-04-04

    ... Analyst, Office of Regional Affairs, Room 7009, Economic Development Administration, Washington, DC 20230... Economic Development Administration Proposed Information Collection; Comment Request; Award Amendment Requests and Project Service Maps AGENCY: Economic Development Administration (EDA), Department of Commerce...

  4. Room for Women : YouTube film

    NARCIS (Netherlands)

    CWI CWI

    2010-01-01

    htmlabstractThe Centrum Wiskunde & Informatica (CWI) signed the "Talent to the Top" Charter. CWI is highlighting the objective of this national task force to enable more women to flow to senior talent positions. To illustrate this CWI created the short film 'Room for Women'. In this film four female

  5. Reading for Pleasure: A Reading Resource Room.

    Science.gov (United States)

    Battles, Jane; Tambuscio, Colleen

    1991-01-01

    A reading resource room was developed for 59 deaf and hard-of-hearing secondary-level students, to improve vocabulary and reading skills and encourage reading for pleasure. Books of interest to teenagers with limited reading levels were located from several publishing companies and were arranged in a space with shelves and comfortable seating.…

  6. Initial Pediatric Assessment in the Emergency Room

    Directory of Open Access Journals (Sweden)

    Eduardo Cázares-Ramírez

    2014-07-01

    In this phase, examining room and laboratory studies are not decisive components. General, or specific, treatment focuses on restoring bodily and physiological homeostasis, in other words to prevent evolution to respiratory failure, shock, or cardiopulmonary insufficiency. It is not the time to make a specific diagnosis.

  7. Recovery room nurses' knowledge regarding postoperative airway ...

    African Journals Online (AJOL)

    Adele

    9. Recovery room nurses' knowledge regarding postoperative airway emergencies in adults in private hospitals in Northern Gauteng,. South Africa. Correspondence: Dr ADH Botha email: annali.botha@up.ac.za. T van Huyssteen. Critical care unit, Zuid-Afrikaans Hospitaal, Muckleneuk, Pretoria, South Africa. ADH Botha.

  8. Mathematical Models for Room Air Distribution - Addendum

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    1982-01-01

    removed from the room at constant penetration length is proportional to the cube of the velocities in the occupied zone. It is also shown that a large number of diffusers increases the amount of heat which may be removed without affecting the thermal conditions. Control strategies for dual duct and single...

  9. Mathematical Models for Room Air Distribution

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    1982-01-01

    removed from the room at constant penetration length is proportional to the cube of the velocities in the occupied zone. It is also shown that a large number of diffusers increases the amount of heat which may be removed without affecting the thermal conditions. Control strategies for dual duct and single...

  10. Mechanochemically assisted room temperature solid state ...

    Indian Academy of Sciences (India)

    This communication reports a novel mechanochemically assisted room temperature solid state metathesis reaction for the synthesis of submicron-size alkaline-earth molybdates crystallizing in a tetragonal Scheelite structure. The solids were characterized by powder XRD, FTIR, TGA, DTA, SEM, EDAX and TEM to ascertain ...

  11. Enhancing training in the main control room

    Energy Technology Data Exchange (ETDEWEB)

    McGuigan, K.; O' Leary, K.; Canavan, K. [Ontario Power Generation, Toronto, Ontario (Canada)

    2004-07-01

    In 2003 Pickering B Nuclear of Ontario Power Generation installed a Desktop Simulator (DTS) in the Main Control Room (MCR) for training purposes. This paper will outline why this training enhancement was undertaken and the approach taken to secure its use in an active MCR environment while minimizing distractions to plant operations. (author)

  12. Room acoustic properties of concert halls

    DEFF Research Database (Denmark)

    Gade, Anders Christian

    1996-01-01

    A large database of values of various room acoustic parameters has provided the basis for statistical analyses of how and how much the acoustic properties of concert halls are influenced by their size, shape, and absorption area (as deduced from measured reverberation time). The data have been...

  13. [Pain assessment in the postanaesthesia recovery room].

    Science.gov (United States)

    Fiorentino, Assunta; Mathieu, Laurent

    2016-09-01

    Pain assessment is an important activity in nursing care. Postanaesthesia recovery rooms are specialised care units. Pain assessment must form part of a global approach, beyond an objective of care. The nurse plays a key role from the reception of the patient through to their transfer to the ward. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  14. Intraoperative and recovery room outcome | Edomwonyi | East ...

    African Journals Online (AJOL)

    Objectives: To identify and quantitate anaesthesia related complications in the intraoperative period and in the post anaesthesia recovery room. Design: A prospective study. Setting: University of Benin Teaching Hospital; a University - affiliated tertiary centre. Subjects: Patients scheduled for elective and emergency surgery ...

  15. Anticipating urgent surgery in operating room departments

    NARCIS (Netherlands)

    van der Lans, M.; Hans, Elias W.; Hurink, Johann L.; Wullink, Gerhard; van Houdenhoven, M.; Kazemier, G.

    2005-01-01

    Operating Room (OR) departments need to create robust surgical schedules that anticipate urgent surgery, while minimizing urgent surgery waiting time and overtime, and maximizing utilization. We consider two levels of planning and control to anticipate urgent surgery. At the tactical level, we study

  16. Pneumothorax in the Emergency Room: personal caseload.

    Science.gov (United States)

    Surleti, S; Famà, F; Murabito, L M; Villari, S A; Bramanti, C C; Gioffrè Florio, M A

    2011-01-01

    The aim of this study was to collect information on the incidence, pathophysiology, treatment and mortality of pneumothorax in the Emergency Room. Pneumothorax is classified as spontaneous (primary, secondary or catamenial) or traumatic (iatrogenic or secondary to a blunt or penetrating chest injury). Between January 2007 and December 2009, 102 patients with pneumothorax were seen in our Emergency Room. Their records were examined and their data collected retrospectively. The type and side of the pneumothorax and age, sex, incidence and mortality were analyzed. The cases, involving 93 males and 9 females, broke down as follows: 68 spontaneous (66.7%), 33 traumatic (32.3%) and one iatrogenic (0.98%). The mean age was 47.3 (range 12-99); the incidence was 0.10%. There were no deaths due to pneumothorax in the Emergency Room. Traumatic pneumothorax was associated with blunt chest trauma, pleural effusion, hemothorax, cranial trauma, fractured collarbone, upper and lower limb fracture, pelvic fracture, vertebral and spinal trauma, sternum fracture and abdominal trauma. Pneumothorax is a common clinical problem. A multidisciplinary approach is essential to reduce the risk of morbidity and mortality. The incidence of pneumothorax in the Emergency Room was similar to that reported in the literature, while mortality data cannot be compared due to the lack of published studies.

  17. Reducing start time delays in operating rooms

    NARCIS (Netherlands)

    Does, R.J.M.M.; Vermaat, T.M.B.; Verver, J.P.S.; Bisgaard, S.; van den Heuvel, J.

    2009-01-01

    Problem: Health care today is facing serious problems: quality of care does not meet patients’ needs and costs are exploding. Inefficient utilization of expensive operating rooms is one of the major problems in many hospitals worldwide. A benchmark study of 13 hospitals in the Netherlands and

  18. The Distributed Virtual Meeting Room Exercise

    NARCIS (Netherlands)

    Nijholt, Antinus; Zwiers, Jakob; Peciva, Jan; Vinciarelli, A.; Odobez, J-M.

    2005-01-01

    In this paper, we describe our research on distributed virtual meeting rooms. Starting point is our research on multi-party interaction, where the interaction may take place in real, augmented and virtual environments. Moreover, those that interact may be humans, human-controlled avatars,

  19. ISOLDE target zone control room HD

    CERN Multimedia

    2016-01-01

    Operating the ISOLDE target handling robots from the dedicated control room in building 197. Monitors showing the movements of the robots (GPS in this case) in the target zone. The footage shows the actual operation by the operator as well as the different equipment such as camera electronics, camera motor controls, camera monitors and Kuka robot controls touch panel.

  20. The Art of Graffiti and Room 161

    Science.gov (United States)

    Forseth, Sonia

    1972-01-01

    Covering the walls of the art room with white paper and sealing off all the open edges with masking tape, students proceeded to do their thing'' by using tempera, oil crayons and India ink to create an environment that was completely their own. (Author/CB)

  1. Healthy Buildings and Air Distribution in Rooms

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    Healthy buildings are to a great extent a question of indoor air quality. The processes involved in air quality can be looked upon as a number of links in a chain. Typical links will be emission from building materials, convection and diffusion in the room, local airflow around a person, personal...

  2. Guidelines on ergonomic aspects of control rooms

    Science.gov (United States)

    Mitchell, C. M.; Bocast, A. K.; Stewart, L. J.

    1983-01-01

    The anthropometry, workstation design, and environmental design of control rooms are outlined. The automated interface and VDTs and displays and various modes of communication between the system and the human operator using VDTs are discussed. The man in the loop is examined, the single controller single task framework and multiple controller multiple tasks issues are considered.

  3. Room-temperature ferromagnetic and photoluminescence ...

    Indian Academy of Sciences (India)

    Similar results were also observed in Co-doped TiO2 nanoparticles reported by. Santara et al [25]. Figure 7 shows the magnetic hysteresis loop of ITO pow- ders at room temperature after subtracting the diamagnetic or paramagnetic background. The ITO powders exhibited the saturation magnetic moment, coercivity and ...

  4. There's Plenty of Room at the Bottom

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 9. There's Plenty of Room at the Bottom. Richard P Feynman. Classics Volume 16 Issue 9 September 2011 pp 890-905. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/09/0890-0905 ...

  5. Video Conferencing for a Virtual Seminar Room

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Fosgerau, A.; Hansen, Peter Søren K.

    2002-01-01

    A PC-based video conferencing system for a virtual seminar room is presented. The platform is enhanced with DSPs for audio and video coding and processing. A microphone array is used to facilitate audio based speaker tracking, which is used for adaptive beam-forming and automatic camera-control...

  6. Room for iodo therapy; Quarto de iodoterapia

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, A.L.A.; Derivi, A.; Bacelar, A.; Ramos, F.R.; Dias, T.M.; Baptista, I.S. [Hospital das Clinicas, Porto Alegre, RS (Brazil). Grupo de Pesquisa e Pos-graduacao em Fisica Medica

    1996-12-31

    A description of rules to assemble, to install and to maintain a room for iodo therapy is presented. The necessities of the patients and procedures to meet the norms of radiologic protection established by the Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil) are highlighted 3 refs.

  7. Reasoning Maps

    OpenAIRE

    Falcão, Renato Pinto de Queiroz

    2003-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção. Esta dissertação apresenta uma ferramenta de apoio à decisão, baseada na Metodologia Multicritérios de Apoio à Decisão - MCDA, através do desenvolvimento de um software denominado Reasoning Maps. O software permite, de maneira integrada, a construção de mapas cognitivos, suas diversas análises topológicas e o cadastramento e análise de alternativas. Abor...

  8. Projective mapping

    DEFF Research Database (Denmark)

    Dehlholm, Christian; Brockhoff, Per B.; Bredie, Wender Laurentius Petrus

    2012-01-01

    instructions and influence heavily the product placements and the descriptive vocabulary (Dehlholm et.al., 2012b). The type of assessors performing the method influences results with an extra aspect in Projective Mapping compared to more analytical tests, as the given spontaneous perceptions are much dependent...... the applied framework, semantic restrictions, the choice of type of assessors and the validation of product separations. The applied framework concerns the response surface as presented to the assessor in different shapes, e.g. rectangular, square or round. Semantic restrictions are a part of the assessor...

  9. Mapping of

    Directory of Open Access Journals (Sweden)

    Sayed M. Arafat

    2014-06-01

    Full Text Available Land cover map of North Sinai was produced based on the FAO-Land Cover Classification System (LCCS of 2004. The standard FAO classification scheme provides a standardized system of classification that can be used to analyze spatial and temporal land cover variability in the study area. This approach also has the advantage of facilitating the integration of Sinai land cover mapping products to be included with the regional and global land cover datasets. The total study area is covering a total area of 20,310.4 km2 (203,104 hectare. The landscape classification was based on SPOT4 data acquired in 2011 using combined multispectral bands of 20 m spatial resolution. Geographic Information System (GIS was used to manipulate the attributed layers of classification in order to reach the maximum possible accuracy. GIS was also used to include all necessary information. The identified vegetative land cover classes of the study area are irrigated herbaceous crops, irrigated tree crops and rain fed tree crops. The non-vegetated land covers in the study area include bare rock, bare soils (stony, very stony and salt crusts, loose and shifting sands and sand dunes. The water bodies were classified as artificial perennial water bodies (fish ponds and irrigated canals and natural perennial water bodies as lakes (standing. The artificial surfaces include linear and non-linear features.

  10. Speaker comfort and increase of voice level in lecture rooms

    DEFF Research Database (Denmark)

    Brunskog, Jonas; Gade, Anders Christian; Bellester, G P

    2008-01-01

    Teachers often suffer health problems or tension related to their voice. These problems may be related to there working environment, including room acoustics of the lecture rooms which forces them to stress their voices. The present paper describes a first effort in finding relationships between...... the objectively measurable parameters of the rooms and the objective voice power produced by speakers. In rooms with different sizes, reverberation time and other physical attributes, the sound power levels produced by six speakers where measured while giving a short lecture. Relevant room acoustic parameters...... that these changes were mainly related to the size of the room and to the gain or support produced by the room. To describe this quality, a new room acoustic quantity called 'room gain' is proposed....

  11. Differentiating Keratoconus and Corneal Warpage by Analyzing Focal Change Patterns in Corneal Topography, Pachymetry, and Epithelial Thickness Maps.

    Science.gov (United States)

    Tang, Maolong; Li, Yan; Chamberlain, Winston; Louie, Derek J; Schallhorn, Julie M; Huang, David

    2016-07-01

    To differentiate between keratoconus and contact lens-related corneal warpage by combining focal change patterns in anterior corneal topography, pachymetry, and epithelial thickness maps. Pachymetry and epithelial thickness maps of normal, keratoconus, and warpage, and forme fruste keratoconus (FFK) eyes were obtained from a Fourier-domain optical coherence tomography (OCT). Epithelial pattern standard deviation (PSD) was calculated and combined with two novel indices, the Warpage Index and the Anterior Ectasia Index, to differentiate between normal, keratoconus, and warpage eyes. The values of the three parameters were compared between groups. The study included 22 normal, 31 keratoconic, 11 warpage, and 8 FFK eyes. The epithelial PSD was normal ( 0.041) for 100% of keratoconic eyes, 81.8% of warpage eyes, and 87.5% of FFK eyes. The Anterior Ectasia Index of normal eyes (1.66 ± 0.74) was significantly lower than that for the keratoconus eyes (17.5 ± 7.17), the warpage eyes (2.98 ± 1.69), and the FFK eyes (6.95 ± 5.86). The Warpage Index was positive in all warpage eyes and negative for all keratoconic and FFK eyes except three wearing rigid gas-permeable contact lens. The epithelial PSD can distinguish normal from keratoconus or warpage, but does not distinguish between these two conditions. The Anterior Ectasia Index is abnormal in keratoconus but not warpage. The Warpage Index is positive for warpage and negative for keratoconus, except in cases where keratoconus and warpage coexist. Together, the three parameters are strong tripartite discriminators of normal, keratoconus, and warpage.

  12. Mapping Resilience

    DEFF Research Database (Denmark)

    Carruth, Susan

    2015-01-01

    Resilience theory is a growing discipline with great relevance for the discipline of planning, particularly in fields like energy planning that face great uncertainty and rapidly transforming contexts. Building on the work of the Stockholm Resilience Centre, this paper begins by outlining...... the relationship between resilience and energy planning, suggesting that planning in, and with, time is a core necessity in this domain. It then reviews four examples of graphically mapping with time, highlighting some of the key challenges, before tentatively proposing a graphical language to be employed...... by planners when aiming to construct resilient energy plans. It concludes that a graphical language has the potential to be a significant tool, flexibly facilitating cross-disciplinary communication and decision-making, while emphasising that its role is to support imaginative, resilient planning rather than...

  13. Perception of Reverberation in Small Rooms

    DEFF Research Database (Denmark)

    Kaplanis, Neofytos; Bech, Søren; Jensen, Søren Holdt

    Reverberation is considered as one of the fundamental perceived properties of an acoustical space. Literature is available on the topic and currently a range of sciences have contributed in understanding the properties of reverberant sound fields and the relevant auditory processes. This paper su...... attributes of reverberation and conclusive measurement data is restricted, especially for small spaces. A proposal for perceptual-based experiments is presented, aiming to further understand the links between physical properties of rooms and their effects on perception....... summarises the current literature following a top-down approach. It identifies the perceptual aspects of reverberation and attempts to establish links to physical measures, focussing on small rooms. Results indicate that the current acoustical metrics often have limited correlation to the perceptual...

  14. Unitary and room air-conditioners

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.E.

    1977-09-01

    The scope of this technology evaluation on room and unitary air conditioners covers the initial investment and performance characteristics needed for estimating the operating cost of air conditioners installed in an ICES community. Cooling capacities of commercially available room air conditioners range from 4000 Btu/h to 36,000 Btu/h; unitary air conditioners cover a range from 6000 Btu/h to 135,000 Btu/h. The information presented is in a form useful to both the computer programmer in the construction of a computer simulation of the packaged air-conditioner's performance and to the design engineer, interested in selecting a suitably sized and designed packaged air conditioner.

  15. Prepare to protect: Operating and maintaining a tornado safe room.

    Science.gov (United States)

    Herseth, Andrew; Goldsmith-Grinspoon, Jennifer; Scott, Pataya

    2017-06-01

    Operating and maintaining a tornado safe room can be critical to the effective continuity of business operations because a firm's most valuable asset is its people. This paper describes aspects of operations and maintenance (O&M) for existing tornado safe rooms as well as a few planning and design aspects that affect the ultimate operation of a safe room for situations where a safe room is planned, but not yet constructed. The information is based on several Federal Emergency Management Agency safe room publications that provide guidance on emergency management and operations, as well as the design and construction of tornado safe rooms.

  16. Room for Women : YouTube film

    OpenAIRE

    CWI, CWI

    2010-01-01

    htmlabstractThe Centrum Wiskunde & Informatica (CWI) signed the "Talent to the Top" Charter. CWI is highlighting the objective of this national task force to enable more women to flow to senior talent positions. To illustrate this CWI created the short film 'Room for Women'. In this film four female scientists are given the opportunity to to tell about the role model for a new generation of scientific talent.

  17. Humanized nursing service in the operating room

    Directory of Open Access Journals (Sweden)

    Cui-ping MU

    2014-06-01

    Full Text Available Objective: To improve the quality of nursing service. Methods: To improve nursing service of the aspects of nursing environment, nursing intervention and nursing aesthetics. Results: To achieve the goal that patient satisfaction rate was 100% and to stimulate the enthusiasm of the medical staff. Conclusion: Humanized nursing service is an effective method of improving efficiency and quality of nursing in the operating room.

  18. Clinical leadership: the elephant in the room.

    Science.gov (United States)

    Edmonstone, John

    2009-01-01

    The article explores the concept of clinical leadership in the National Health Service in the UK by seeking to establish a workable definition and by contrasting it with managerial leadership, focussing on the 'disconnected hierarchy' in professional organizations. It proposes that the problems faced by clinical leadership relate to the current nature of general management in the NHS and concludes by suggesting that clinical leadership is the 'elephant in the room'-often ignored or unaddressed.

  19. Electric control of magnetism at room temperature

    OpenAIRE

    Wang, Liaoyu; Wang, Dunhui; Cao, Qingqi; Zheng, Yuanxia; Xuan, Haicheng; Gao, Jinlong; Du, Youwei

    2012-01-01

    In the single-phase multiferroics, the coupling between electric polarization (P) and magnetization (M) would enable the magnetoelectric (ME) effect, namely M induced and modulated by E, and conversely P by H. Especially, the manipulation of magnetization by an electric field at room-temperature is of great importance in technological applications, such as new information storage technology, four-state logic device, magnetoelectric sensors, low-power magnetoelectric device and so on. Furtherm...

  20. Radiation Protection Elephants in the Room

    Energy Technology Data Exchange (ETDEWEB)

    Vetter, R. J.

    2004-07-01

    As our system of radiological protection evolves, several significant issues loom within radiation protection discussions and publications. These issues influence the nature of epidemiological and radiobiological research and the establishment of radiation protection recommendations, standards, and regulations. These issues are like the proverbial ''elephants in the room''. They are large, and it is unwise to ignore them. This paper discusses the impact of three young elephants as they make their presence increasingly obvious: increased cancer susceptibility from early-life exposure to radiation, terrorism and fear of radiation, and patient safety. Increased cancer susceptibility from early-life exposure to radiation is emerging as a discussion topic related to the safety of computed tomography (CT) and other medical modalities. Shortly after publication of CT dose data, manufacturers were helping to reduce doses to children by increasing flexibility for adjustment of technique factors. Also, radiation epidemiological data are being used in the development of guidance on exposure to chemical carcinogens during early life. Re-emergence of public fear of radiation has been fueled by threats of radiological dispersion devises and confusing messages about personal decontamination, emergency room acceptance or rejection of contaminated victims, and environmental clean-up. Finally, several professional publications have characterized risk of medical radiation exposure in terms of patient deaths even though epidemiological data do not support such conclusions. All three of these elephants require excellent science and sophisticated data analysis to coax them from the room. Anecdotal communications that confuse the public should be avoided. These are not the only elephants in the room, but these three are making their presence increasingly obvious. This paper discusses the need for radiation protection professionals to rely on good science in the

  1. White Paper for Virtual Control Room

    Science.gov (United States)

    Little, William; Tully-Hanson, Benjamin

    2015-01-01

    The Virtual Control Room (VCR) Proof of Concept (PoC) project is the result of an award given by the Fourth Annual NASA T&I Labs Challenge Project Call. This paper will outline the work done over the award period to build and enhance the capabilities of the Augmented/Virtual Reality (AVR) Lab at NASA's Kennedy Space Center (KSC) to create the VCR.

  2. Human echolocation in different situations and rooms.

    Science.gov (United States)

    Schenkman, Bo N

    2017-05-01

    People, especially when blind, use echolocation to detect obstacles, orient themselves, and get an awareness of their environment. I and coworkers have, with mostly psychophysical methods, studied perceptual aspects of how people accomplish echolocation. Echolocation with long canes while walking was possible but difficult. The effects of the spectral composition of the emitted sounds had no effects. Sound recordings in anechoic and conference rooms from non-walking, static situations, later presented in a laboratory showed a better performance in an ordinary room with reflections, than in an anechoic room. We also found that there was a higher performance with longer sounding sounds than for short clicks. Among the difficulties for the blind are how to avoid masking of sounds. A few blind are exceptionally high performing. An "information-surplus principle" has been proposed. Various information sources are used, but repetition pitch seems more important than loudness for echolocation. Among other sources, timbre may also provide information. There may exist a time gap, acoustic gaze, for how blind people use clicks. It is likely also that there are at least two processes taking place in the hearing system when listening for echoes, one attuned to short sounds and one to long sounds.

  3. Online estimation of room reverberation time

    Science.gov (United States)

    Ratnam, Rama; Jones, Douglas L.; Wheeler, Bruce C.; Feng, Albert S.

    2003-04-01

    The reverberation time (RT) is an important parameter for characterizing the quality of an auditory space. Sounds in reverberant environments are subject to coloration. This affects speech intelligibility and sound localization. State-of-the-art signal processing algorithms for hearing aids are expected to have the ability to evaluate the characteristics of the listening environment and turn on an appropriate processing strategy accordingly. Thus, a method for the characterization of room RT based on passively received microphone signals represents an important enabling technology. Current RT estimators, such as Schroeder's method or regression, depend on a controlled sound source, and thus cannot produce an online, blind RT estimate. Here, we describe a method for estimating RT without prior knowledge of sound sources or room geometry. The diffusive tail of reverberation was modeled as an exponentially damped Gaussian white noise process. The time constant of the decay, which provided a measure of the RT, was estimated using a maximum-likelihood procedure. The estimates were obtained continuously, and an order-statistics filter was used to extract the most likely RT from the accumulated estimates. The procedure was illustrated for connected speech. Results obtained for simulated and real room data are in good agreement with the real RT values.

  4. Display Developer for Firing Room Applications

    Science.gov (United States)

    Bowman, Elizabeth A.

    2013-01-01

    The firing room at Kennedy Space Center (KSC) is responsible for all NASA human spaceflight launch operations, therefore it is vital that all displays within the firing room be properly tested, up-to-date, and user-friendly during a launch. The Ground Main Propulsion System (GMPS) requires a number of remote displays for Vehicle Integration and Launch (VIL) Operations at KSC. My project is to develop remote displays for the GMPS using the Display Services and Framework (DSF) editor. These remote displays will be based on model images provided by GMPS through PowerPoint. Using the DSF editor, the PowerPoint images can be recreated with active buttons associated with the correct Compact Unique Identifiers (CUIs). These displays will be documented in the Software Requirements and Design Specifications (SRDS) at the 90% GMPS Design Review. In the future, these remote displays will be available for other developers to improve, edit, or add on to so that the display may be incorporated into the firing room to be used for launches.

  5. Reference frames in learning from maps and navigation.

    Science.gov (United States)

    Meilinger, Tobias; Frankenstein, Julia; Watanabe, Katsumi; Bülthoff, Heinrich H; Hölscher, Christoph

    2015-11-01

    In everyday life, navigators often consult a map before they navigate to a destination (e.g., a hotel, a room, etc.). However, not much is known about how humans gain spatial knowledge from seeing a map and direct navigation together. In the present experiments, participants learned a simple multiple corridor space either from a map only, only from walking through the virtual environment, first from the map and then from navigation, or first from navigation and then from the map. Afterwards, they conducted a pointing task from multiple body orientations to infer the underlying reference frames. We constructed the learning experiences in a way such that map-only learning and navigation-only learning triggered spatial memory organized along different reference frame orientations. When learning from maps before and during navigation, participants employed a map- rather than a navigation-based reference frame in the subsequent pointing task. Consequently, maps caused the employment of a map-oriented reference frame found in memory for highly familiar urban environments ruling out explanations from environmental structure or north preference. When learning from navigation first and then from the map, the pattern of results reversed and participants employed a navigation-based reference frame. The priority of learning order suggests that despite considerable difference between map and navigation learning participants did not use the more salient or in general more useful information, but relied on the reference frame established first.

  6. Mapping the Climate.

    Science.gov (United States)

    1981-01-19

    Computer Mapping in Geoecology , The Harvard Library of Computer Graphics, 1979 Mapping Collection, Vol. 5, pp 11-27. 5. Robinson, A.H. (1974) A New Map...Use of Synagraphic Computer Mapping in Geoecology , The Harvard Library of Computer Graphics, 1979 Mapping Collection, Vol. 5, pp 11-27. 5. Robinson, A

  7. Human Mind Maps

    Science.gov (United States)

    Glass, Tom

    2016-01-01

    When students generate mind maps, or concept maps, the maps are usually on paper, computer screens, or a blackboard. Human Mind Maps require few resources and little preparation. The main requirements are space where students can move around and a little creativity and imagination. Mind maps can be used for a variety of purposes, and Human Mind…

  8. Personal Exposure in a Ventilated Room with Concentration Gradients

    DEFF Research Database (Denmark)

    Brohus, Henrik; Nielsen, Peter V.

    This paper deals with personal exposure in rooms with concentration gradients and persons present. Results from case studies including a breathing thermal manikin in a displacement ventilated room and in a wind channel are presented.......This paper deals with personal exposure in rooms with concentration gradients and persons present. Results from case studies including a breathing thermal manikin in a displacement ventilated room and in a wind channel are presented....

  9. Reliability of estimating the room volume from a single room impulse response.

    Science.gov (United States)

    Kuster, Martin

    2008-08-01

    The methods investigated for the room volume estimation are based on geometrical acoustics, eigenmode, and diffuse field models and no data other than the room impulse response are available. The measurements include several receiver positions in a total of 12 rooms of vastly different sizes and acoustic characteristics. The limitations in identifying the pivotal specular reflections of the geometrical acoustics model in measured room impulse responses are examined both theoretically and experimentally. The eigenmode method uses the theoretical expression for the Schroeder frequency and the difficulty of accurately estimating this frequency from the varying statistics of the room transfer function is highlighted. Reliable results are only obtained with the diffuse field model and a part of the observed variance in the experimental results is explained by theoretical expressions for the standard deviation of the reverberant sound pressure and the reverberation time. The limitations due to source and receiver directivity are discussed and a simple volume estimation method based on an approximate relationship with the reverberation time is also presented.

  10. Electroacoustical simulation of listening room acoustics for project ARCHIMEDES

    DEFF Research Database (Denmark)

    Bech, Søren

    1989-01-01

    the influence of listening room acoustics on the timbre of reproduced sound. For simulation of the acoustics of a standard listening room, an electroacoustic setup has been built in an anechoic chamber. The setup is based on a computer model of the listening room, and it consists of a number of loudspeakers...

  11. 32 CFR 806.11 - FOIA reading rooms.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false FOIA reading rooms. 806.11 Section 806.11... FREEDOM OF INFORMATION ACT PROGRAM § 806.11 FOIA reading rooms. Each FOIA office will arrange for a reading room where the public may inspect releasable records. You do not need to co-locate the reading...

  12. 22 CFR 171.4 - Electronic reading room.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Electronic reading room. 171.4 Section 171.4... PUBLIC General Policy and Procedures § 171.4 Electronic reading room. The Department has established a... public reading room. This site also contains information on accessing records under the FOIA and the...

  13. 36 CFR 1600.2 - Public reading room.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Public reading room. 1600.2... Records Under the Freedom of Information Act § 1600.2 Public reading room. (a) The Foundation maintains a public reading room that contains the records that the FOIA requires to be made regularly available for...

  14. 25 CFR 517.2 - Public reading room.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Public reading room. 517.2 Section 517.2 Indians NATIONAL... PROCEDURES § 517.2 Public reading room. Records that are required to be maintained by the Commission shall be available for public inspection and copying at 1441 L Street, NW., Suite 9100 Washington, DC. Reading room...

  15. 12 CFR 505.2 - Public Reading Room.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Public Reading Room. 505.2 Section 505.2 Banks....2 Public Reading Room. OTS will make materials available for review on an ad hoc basis when..., or you may visit the Public Reading Room at 1700 G Street, NW., by appointment only. (Please identify...

  16. 40 CFR 1601.12 - Public reading room.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Public reading room. 1601.12 Section... DISCLOSURE OF RECORDS UNDER THE FREEDOM OF INFORMATION ACT Administration § 1601.12 Public reading room. (a) The CSB maintains a public reading room that contains the records that the FOIA requires to be made...

  17. 29 CFR 70.4 - Public reading rooms.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Public reading rooms. 70.4 Section 70.4 Labor Office of the Secretary of Labor PRODUCTION OR DISCLOSURE OF INFORMATION OR MATERIALS General § 70.4 Public reading rooms... this section are available through public reading rooms, and, to the extent indicated in this paragraph...

  18. 39 CFR 265.5 - Public reading rooms.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Public reading rooms. 265.5 Section 265.5 Postal... reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260-1641, serves as public reading room for the materials which are listed in paragraphs (a)(2), (3), (4...

  19. 30 CFR 42.50 - Charges for room and board.

    Science.gov (United States)

    2010-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR FILING AND OTHER ADMINISTRATIVE REQUIREMENTS NATIONAL MINE HEALTH AND SAFETY ACADEMY Room and Board § 42.50 Charges for room and board. The Academy will charge room and board to all persons staying at the Academy, except MSHA...

  20. 7 CFR 58.620 - Freezing and packaging rooms.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Freezing and packaging rooms. 58.620 Section 58.620 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....620 Freezing and packaging rooms. The rooms used for freezing and packaging frozen desserts shall be...

  1. 46 CFR 111.105-41 - Battery rooms.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Battery rooms. 111.105-41 Section 111.105-41 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-41 Battery rooms. Each electrical installation in a battery room...

  2. 46 CFR 168.15-30 - Toilet rooms.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Toilet rooms. 168.15-30 Section 168.15-30 Shipping COAST... Accommodations § 168.15-30 Toilet rooms. (a) There must be provided 1 toilet for each 10 persons or fraction... toilet rooms must be located convenient to the sleeping quarters of the persons to which they are...

  3. A stochastic approach for solving the operating room scheduling problem

    NARCIS (Netherlands)

    Molina-Pariente, Jose M.; Hans, Elias W.; Framinan, Jose M.

    2016-01-01

    We address a stochastic operating room scheduling problem which consists of assigning an intervention date and operating room to surgeries on the waiting list, minimizing the under- and overtime costs of the operating rooms, and the cost of exceeding the capacity constraints of the system.

  4. 49 CFR 192.631 - Control room management.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Control room management. 192.631 Section 192.631... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Operations § 192.631 Control room management. (a... operator must have and follow written control room management procedures that implement the requirements of...

  5. 49 CFR 195.446 - Control room management.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Control room management. 195.446 Section 195.446... PIPELINE Operation and Maintenance § 195.446 Control room management. (a) General. This section applies to... written control room management procedures that implement the requirements of this section. The procedures...

  6. 7 CFR 58.413 - Cutting and packaging rooms.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Cutting and packaging rooms. 58.413 Section 58.413....413 Cutting and packaging rooms. When small packages of cheese are cut and wrapped, separate rooms shall be provided for the cleaning and preparation of the bulk cheese and for the cutting and wrapping...

  7. Concept Mapping

    Science.gov (United States)

    Brennan, Laura K.; Brownson, Ross C.; Kelly, Cheryl; Ivey, Melissa K.; Leviton, Laura C.

    2016-01-01

    Background From 2003 to 2008, 25 cross-sector, multidisciplinary community partnerships funded through the Active Living by Design (ALbD) national program designed, planned, and implemented policy and environmental changes, with complementary programs and promotions. This paper describes the use of concept-mapping methods to gain insights into promising active living intervention strategies based on the collective experience of community representatives implementing ALbD initiatives. Methods Using Concept Systems software, community representatives (n=43) anonymously generated actions and changes in their communities to support active living (183 original statements, 79 condensed statements). Next, respondents (n=26, from 23 partnerships) sorted the 79 statements into self-created categories, or active living intervention approaches. Respondents then rated statements based on their perceptions of the most important strategies for creating community changes (n=25, from 22 partnerships) and increasing community rates of physical activity (n=23, from 20 partnerships). Cluster analysis and multidimensional scaling were used to describe data patterns. Results ALbD community partnerships identified three active living intervention approaches with the greatest perceived importance to create community change and increase population levels of physical activity: changes to the built and natural environment, partnership and collaboration efforts, and land-use and transportation policies. The relative importance of intervention approaches varied according to subgroups of partnerships working with different populations. Conclusions Decision makers, practitioners, and community residents can incorporate what has been learned from the 25 community partnerships to prioritize active living policy, physical project, promotional, and programmatic strategies for work in different populations and settings. PMID:23079266

  8. Room Temperature Ferromagnetic Mn:Ge(001

    Directory of Open Access Journals (Sweden)

    George Adrian Lungu

    2013-12-01

    Full Text Available We report the synthesis of a room temperature ferromagnetic Mn-Ge system obtained by simple deposition of manganese on Ge(001, heated at relatively high temperature (starting with 250 °C. The samples were characterized by low energy electron diffraction (LEED, scanning tunneling microscopy (STM, high resolution transmission electron microscopy (HRTEM, X-ray photoelectron spectroscopy (XPS, superconducting quantum interference device (SQUID, and magneto-optical Kerr effect (MOKE. Samples deposited at relatively elevated temperature (350 °C exhibited the formation of ~5–8 nm diameter Mn5Ge3 and Mn11Ge8 agglomerates by HRTEM, while XPS identified at least two Mn-containing phases: the agglomerates, together with a Ge-rich MnGe~2.5 phase, or manganese diluted into the Ge(001 crystal. LEED revealed the persistence of long range order after a relatively high amount of Mn (100 nm deposited on the single crystal substrate. STM probed the existence of dimer rows on the surface, slightly elongated as compared with Ge–Ge dimers on Ge(001. The films exhibited a clear ferromagnetism at room temperature, opening the possibility of forming a magnetic phase behind a nearly ideally terminated Ge surface, which could find applications in integration of magnetic functionalities on semiconductor bases. SQUID probed the co-existence of a superparamagnetic phase, with one phase which may be attributed to a diluted magnetic semiconductor. The hypothesis that the room temperature ferromagnetic phase might be the one with manganese diluted into the Ge crystal is formulated and discussed.

  9. Room Temperature Ferromagnetic Mn:Ge(001).

    Science.gov (United States)

    Lungu, George Adrian; Stoflea, Laura Elena; Tanase, Liviu Cristian; Bucur, Ioana Cristina; Răduţoiu, Nicoleta; Vasiliu, Florin; Mercioniu, Ionel; Kuncser, Victor; Teodorescu, Cristian-Mihail

    2013-12-27

    We report the synthesis of a room temperature ferromagnetic Mn-Ge system obtained by simple deposition of manganese on Ge(001), heated at relatively high temperature (starting with 250 °C). The samples were characterized by low energy electron diffraction (LEED), scanning tunneling microscopy (STM), high resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), superconducting quantum interference device (SQUID), and magneto-optical Kerr effect (MOKE). Samples deposited at relatively elevated temperature (350 °C) exhibited the formation of ~5-8 nm diameter Mn₅Ge₃ and Mn11Ge₈ agglomerates by HRTEM, while XPS identified at least two Mn-containing phases: the agglomerates, together with a Ge-rich MnGe~2.5 phase, or manganese diluted into the Ge(001) crystal. LEED revealed the persistence of long range order after a relatively high amount of Mn (100 nm) deposited on the single crystal substrate. STM probed the existence of dimer rows on the surface, slightly elongated as compared with Ge-Ge dimers on Ge(001). The films exhibited a clear ferromagnetism at room temperature, opening the possibility of forming a magnetic phase behind a nearly ideally terminated Ge surface, which could find applications in integration of magnetic functionalities on semiconductor bases. SQUID probed the co-existence of a superparamagnetic phase, with one phase which may be attributed to a diluted magnetic semiconductor. The hypothesis that the room temperature ferromagnetic phase might be the one with manganese diluted into the Ge crystal is formulated and discussed.

  10. ShakeMap

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — ShakeMap is a product of the USGS Earthquake Hazards Program in conjunction with the regional seismic networks. ShakeMaps provide near-real-time maps of ground...

  11. Impact of furnishing on room airflow

    DEFF Research Database (Denmark)

    2008-01-01

    In building simulation it is common to use idealized empty rooms for simulation. However, furnishing elements may cause local microclimates. These microclimates can be critical for instance if furniture is placed close to poorly insulated external walls in Nordic countries, where the external...... an investigation of the airflow patterns behind a piece of furniture placed near a cold external wall. The investigation is based on a combination of Particle Image Velocimetry experiments and Computational Fluid Dynamics. The main topic of the investigation is to highlight the effect of increasing the distance...

  12. Concentration Distribution in a Mixing Ventilated Room

    DEFF Research Database (Denmark)

    Jensen, Rasmus Lund; Pedersen, D. N.; Nielsen, Peter Vilhelm

    2001-01-01

    Today there is an increasing focus on the importance of a proper ventilation system to obtain good working conditions in the term of air and thermal quality to ensure high productivity. Different ventilation principles are used, e.g., mixing ventilation and displacement ventilation. In order....... Full scale experiments along with a breathing thermal manikin (BTM) have been used. The results show that the location of the sources is of great importance, just as well as temperature differences. Furthermore, the concentration in the breathing zone showed large differences throughout the room....

  13. COCOMO based on Clean room Development Methodology

    OpenAIRE

    Mahesh Bahadur Singh; Hradesh Kumar; Anendra Kumar

    2011-01-01

    The typical software lifecycle is about 40% design, 20% code, and 40% unit testing. The Clean room lifecycle is 80% design and 20% code and no unit test. And effort estimation using the COCOMO(constructive cost model) is based on the typical software lifecycle. In Detail COCOMO, Plan/requirement 6% to 8% (Effort); 10% to 40%(Time) Product Design 16% to 18% (Effort); 19% to 38% (Time) Programming 48% to 68% (Effort); 24% to 64% (Time) Integration/Test 16% to 34% (Effort); 24% to 64% (Time) is...

  14. Loss of conductivity in operating room shoes.

    Science.gov (United States)

    Kulis, E; Newell, J C

    1978-01-01

    The effect of dirt encountered during normal use on the conductivity of operating room footwear has been studied. Booties, sneakers, and shoes having relatively larger conductive area remained conductive throughout the testing period. Shoes and clogs having relatively smaller conductive contact area were found to lose conductivity sooner, and, in more cases, than any other type of footwear tested. The size of the conductive contact area appears to correlate with the length of time that conductive footwear will remain within resistance specification during use.

  15. Diffraction and diffusion in room acoustics

    DEFF Research Database (Denmark)

    Rindel, Jens Holger; Rasmussen, Birgit

    1996-01-01

    Diffraction and diffusion are two phenomena that are both related to the wave nature of sound. Diffraction due to the finite size of reflecting surfaces and the design of single reflectors and reflector arrays are discussed. Diffusion is the result of scattering of sound reflected from surfaces...... that are not plane but curved or irregular. The importance of diffusion has been demonstrated in concert halls. Methods for the design of diffusing surfaces and the development of new types of diffusers are reviewed. Finally, the importance of diffraction and diffusion in room acoustic computer models is discussed....

  16. Prediction of room acoustical parameters (A)

    DEFF Research Database (Denmark)

    Gade, Anders Christian

    1991-01-01

    During a 6-yr period, detailed room acoustical measurements have been carried out in 35 halls in Denmark and in other European countries. By subjecting these data to statistical analyses, it has been possible to confirm old and establish new relationships between design variables and the position......-averaged acoustical data. The results are presented in the form of linear, multiple regression formulas that may be used to predict the values of the newer measures of level, clarity, spaciousness, and musicians' conditions on the orchestra platform in halls with given RT and geometry....

  17. Firing Room Remote Application Software Development

    Science.gov (United States)

    Liu, Kan

    2015-01-01

    The Engineering and Technology Directorate (NE) at National Aeronautics and Space Administration (NASA) Kennedy Space Center (KSC) is designing a new command and control system for the checkout and launch of Space Launch System (SLS) and future rockets. The purposes of the semester long internship as a remote application software developer include the design, development, integration, and verification of the software and hardware in the firing rooms, in particular with the Mobile Launcher (ML) Launch Accessories (LACC) subsystem. In addition, a software test verification procedure document was created to verify and checkout LACC software for Launch Equipment Test Facility (LETF) testing.

  18. Lozi-like maps

    OpenAIRE

    Misiurewicz, Michal; Štimac, Sonja

    2017-01-01

    We define a broad class of piecewise smooth plane homeomorphisms which have properties similar to the properties of Lozi maps, including the existence of a hyperbolic attractor. We call those maps Lozi-like. For those maps one can apply our previous results on kneading theory for Lozi maps. We show a strong numerical evidence that there exist Lozi-like maps that have kneading sequences different than those of Lozi maps.

  19. Mapping Mutations on Phylogenies

    DEFF Research Database (Denmark)

    Nielsen, Rasmus

    2005-01-01

    This chapter provides a short review of recent methodologies developed for mapping mutations on phylogenies. Mapping of mutations, or character changes in general, using the maximum parsimony principle has been one of the most powerful tools in phylogenetics, and it has been used in a variety...... uncertainty in the mapping. Recently developed probabilistic methods can incorporate statistical uncertainty in the character mappings. In these methods, focus is on a probability distribution of mutational mappings instead of a single estimate of the mutational mapping....

  20. Evaluating the auralization of a small room in a virtual sound environment using objective room acoustic measures

    DEFF Research Database (Denmark)

    Ahrens, Axel; Marschall, Marton; Dau, Torsten

    2016-01-01

    of the room. The auralizations were generated using the loudspeaker-based room auralization toolbox (LoRA; Favrot and Buchholz, 2010) and reproduced in a 64-channel loudspeaker array, set up in an anechoic chamber. Differences between the objective measures evaluated in the real and the virtual room were...

  1. Evaluating the auralization of a small room in a virtual sound environment using objective room acoustic measures

    DEFF Research Database (Denmark)

    Ahrens, Axel; Marschall, Marton; Dau, Torsten

    ) & reverberation time (T20, T30); - clarity (C7, C50, C80); - interaural cross-correlation (IACC); - speech transmission index (STI); - direct-to-reverberant ratio (DRR). Impulse responses (IRs) were measured in an IEC listening room. The room was then modeled in the room acoustics software ODEON, and the same...

  2. Room acoustic transition time based on reflection overlap

    DEFF Research Database (Denmark)

    Jeong, Cheol-Ho; Brunskog, Jonas; Jacobsen, Finn

    2013-01-01

    at time t, which is mainly controlled by the absorption characteristics of the boundary surfaces of the room. Scattering, diffuse reflections, and diffraction, which facilitate the overlapping process, have not been taken into account. Measured impulse responses show that the transition occurs earlier......A transition time is defined based on the temporal overlap of reflected pulses in room impulse responses. Assuming specular reflections only, the temporal distance between adjacent reflections, which is proportional to the volume of a room, is compared with the characteristic width of a pulse...... in a room with nonuniform absorption and furniture than in a room that satisfies the underlying assumptions....

  3. Room acoustic transition time based on reflection overlap

    DEFF Research Database (Denmark)

    Jeong, Cheol-Ho; Brunskog, Jonas; Jacobsen, Finn

    2010-01-01

    at time t, which is mainly controlled by the absorption characteristics of the boundary surfaces of the room. Scattering, diffuse reflections, and diffraction, which facilitate the overlapping process, have not been taken into account. Measured impulse responses show that the transition occurs earlier......A transition time is defined based on the temporal overlap of reflected pulses in room impulse responses. Assuming specular reflections only, the temporal distance between adjacent reflections, which is proportional to the volume of a room, is compared with the characteristic width of a pulse...... in a room with nonuniform absorption and furniture than in a room that satisfies the underlying assumptions....

  4. Fast rendering of scanned room geometries

    DEFF Research Database (Denmark)

    Olesen, Søren Krarup; Markovic, Milos; Hammershøi, Dorte

    2014-01-01

    .g. the range detection sensors used in the kinect device. This device provides a high rate of range data, which can be combined to give a very detailed map of the surrounding geometry. Such data was captured and has been presented in an earlier paper, incl. a demonstration of the principle of voxel...

  5. Efficiency improvement in the operating room.

    Science.gov (United States)

    Fong, Abigail J; Smith, Meghan; Langerman, Alexander

    2016-08-01

    In the changing health care environment, health systems, hospitals, and health care providers must focus on improving efficiency to meet an increasing demand for high-quality, low-cost health care. Much has been written about strategies and efforts to improve efficiency in the perioperative periods, yet the time when the patient is in the operating room-the intraoperative period-has received less attention. Yet, this is the period in which surgeons may have the most influence. Systematically review published efforts to improve intraoperative efficiency; assess the outcomes of these efforts, and propose standardized reporting of future studies. A total of 39 studies were identified that met inclusion criteria. These divided naturally into small (single operative team), medium (multi-operative team), and large (institutional) interventions. Most studies used time or money as their metric for efficiency, though others were used as well. There is substantial opportunity to enhance operating room efficiency during the intraoperative period. Surgeons may have a particular role in procedural efficiency, which has been relatively unstudied. Common themes were standardizing tasks, collecting and using actionable data, and maintaining effective team communication. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Tritium Room Air Monitor Operating Experience Review

    Energy Technology Data Exchange (ETDEWEB)

    L. C. Cadwallader; B. J. Denny

    2008-09-01

    Monitoring the breathing air in tritium facility rooms for airborne tritium is a radiological safety requirement and a best practice for personnel safety. Besides audible alarms for room evacuation, these monitors often send signals for process shutdown, ventilation isolation, and cleanup system actuation to mitigate releases and prevent tritium spread to the environment. Therefore, these monitors are important not only to personnel safety but also to public safety and environmental protection. This paper presents an operating experience review of tritium monitor performance on demand during small (1 mCi to 1 Ci) operational releases, and intentional airborne inroom tritium release tests. The tritium tests provide monitor operation data to allow calculation of a statistical estimate for the reliability of monitors annunciating in actual tritium gas airborne release situations. The data show a failure to operate rate of 3.5E-06/monitor-hr with an upper bound of 4.7E-06, a failure to alarm on demand rate of 1.4E-02/demand with an upper bound of 4.4E-02, and a spurious alarm rate of 0.1 to 0.2/monitor-yr.

  7. Data for Room Fire Model Comparisons.

    Science.gov (United States)

    Peacock, Richard D; Davis, Sanford; Babrauskas, Vytenis

    1991-01-01

    With the development of models to predict fire growth and spread in buildings, there has been a concomitant evolution in the measurement and analysis of experimental data in real-scale fires. This report presents the types of analyses that can be used to examine large-scale room fire test data to prepare the data for comparison with zone-based fire models. Five sets of experimental data which can be used to test the limits of a typical two-zone fire model are detailed. A standard set of nomenclature describing the geometry of the building and the quantities measured in each experiment is presented. Availability of ancillary data (such as smaller-scale test results) is included. These descriptions, along with the data (available in computer-readable form) should allow comparisons between the experiment and model predictions. The base of experimental data ranges in complexity from one room tests with individual furniture items to a series of tests conducted in a multiple story hotel equipped with a zoned smoke control system.

  8. Surgeon Awareness of Operating Room Supply Costs.

    Science.gov (United States)

    Jackson, Christopher R; Eavey, Roland D; Francis, David O

    2016-05-01

    The extent to which surgeons understand costs associated with expensive operative procedures remains unclear. The goal of the study was to better understand surgeon cost awareness of operating room supplies and implants. This was a cross-sectional study of faculty (n = 24) and trainees (fellow and residents, n = 27) in the Department of Otolaryngology. Participants completed surveys to assess opinions on importance of cost and ease in accessing cost data and were asked to estimate the costs of operating room (OR) supplies and implants. Estimates within 20% of actual cost were considered correct. Analyses were stratified into faculty and trainee surgeons. Cost estimates varied widely, with a low percentage of correct estimations (25% for faculty, 12% for trainees). Surgeons tended to underestimate the cost of high-cost items (55%) and overestimate the cost of low-cost items (77%). Attending surgeons were more accurate at correctly estimating costs within their own subspecialty (33% vs 16%, P cost knowledge and years in practice did not correlate with cost accuracy (P costs of items/implants used in their OR. An opportunity exists to improve the mechanisms by which cost data are fed back to physicians to help promote value-based decision making. © The Author(s) 2015.

  9. Materials for room temperature magnetic refrigeration

    Energy Technology Data Exchange (ETDEWEB)

    Rosendahl Hansen, B.

    2010-07-15

    Magnetic refrigeration is a cooling method, which holds the promise of being cleaner and more efficient than conventional vapor-compression cooling. Much research has been done during the last two decades on various magnetic materials for this purpose and today a number of materials are considered candidates as they fulfill many of the requirements for a magnetic refrigerant. However, no one material stands out and the field is still active with improving the known materials and in the search for a better one. Magnetic cooling is based on the magnetocaloric effect, which causes a magnetic material to change its temperature when a magnetic field is applied or removed. For room temperature cooling, one utilizes that the magnetocaloric effect peaks near magnetic phase transitions and so the materials of interest all have a critical temperature within the range of 250 - 310 K. A magnetic refrigerant should fulfill a number of criteria, among these a large magnetic entropy change, a large adiabatic temperature change, preferably little to no thermal or magnetic hysteresis and the material should have the stability required for long term use. As the temperature range required for room temperature cooling is some 40 - 50 K, the magnetic refrigerant should also be able to cover this temperature span either by exhibiting a very broad peak in magnetocaloric effect or by providing the opportunity for creating a materials series with varying transition temperatures. (Author)

  10. Concentrations of methoxyflurane and nitrous oxide in veterinary operating rooms

    Energy Technology Data Exchange (ETDEWEB)

    Ward, G.S.; Byland, R.R.

    1982-02-01

    The surgical rooms of 14 private veterinary practices were monitored to determined methoxyflurane (MOF) concentrations during surgical procedure under routine working conditions. The average room volume for these 14 rooms was 29 m3. The average MOF value for all rooms was 2.3 ppm, with a range of 0.7 to 7.4 ppm. Four of the 14 rooms exceeded the maximum recommended concentration of 2 ppm. Six rooms which had 6 or more air changes/hr averaged 1.1 ppm, whereas 8 rooms with less than 6 measurable air changes/hr averaged 3.2 ppm. Operating rooms that had oxygen flows of more than 1,000 cm3/min averaged 4.4 ppm, whereas those with flows of less than 1,000 cm3/min averaged 1.5 ppm. The average time spent during a surgical procedure using MOF, for all 14 facilities, was 2 hours. Nitrous oxide (N/sub 2/O) concentrations were determined in 4 veterinary surgical rooms. The average N/sub 2/O concentration for 3 rooms without waste anesthetic gas scavenging was 138 ppm. Concentration of N/sub 2/O in the waste anesthetic gas-scavenged surgical room was 14 ppm, which was below the maximum recommended concentration of 25 ppm.

  11. Experimental and numerical comparison of absorption optimization in small rooms

    DEFF Research Database (Denmark)

    Wincentz, Jakob Nygård; Garcia, Julian Martinez-Villalba; Jeong, Cheol-Ho

    2016-01-01

    A vast majority of modern music is recorded and produced in small control room environments of volumes of around 50 m3 . Several problems occur when controlling the room acoustics of such small spaces. First, the room modes will produce strong peaks and dips particularly at lower frequencies......, and even in the sweet spot position the listening experience can be easily deteriorated. Second, when designing or refurbishing small rooms it is hard to adequately predict the reverberation time by using Sabine’s formula due to highly non-diffuse conditions and using a statistical approach below...... the Schroeder frequency. This project investigates experimentally changes in the room acoustic parameters by altering the positioning and orientation of porous materials in a small room, which are compared with finite element method (FEM) simulations. FEM is able to take into account the exact room geometry...

  12. Speech intelligibility in rooms: Effect of prior listening exposure interacts with room acoustics.

    Science.gov (United States)

    Zahorik, Pavel; Brandewie, Eugene J

    2016-07-01

    There is now converging evidence that a brief period of prior listening exposure to a reverberant room can influence speech understanding in that environment. Although the effect appears to depend critically on the amplitude modulation characteristic of the speech signal reaching the ear, the extent to which the effect may be influenced by room acoustics has not been thoroughly evaluated. This study seeks to fill this gap in knowledge by testing the effect of prior listening exposure or listening context on speech understanding in five different simulated sound fields, ranging from anechoic space to a room with broadband reverberation time (T60) of approximately 3 s. Although substantial individual variability in the effect was observed and quantified, the context effect was, on average, strongly room dependent. At threshold, the effect was minimal in anechoic space, increased to a maximum of 3 dB on average in moderate reverberation (T60 = 1 s), and returned to minimal levels again in high reverberation. This interaction suggests that the functional effects of prior listening exposure may be limited to sound fields with moderate reverberation (0.4 ≤ T60 ≤ 1 s).

  13. Room for the River: Room for Research? The case of depoldering De Noordwaard, the Netherlands

    NARCIS (Netherlands)

    Schut, M.; Leeuwis, C.; Paassen, van A.

    2010-01-01

    This paper explores the role of research in the context of the Dutch spatial planning procedure ‘Room for the River’. We start from the idea that research is strategically used to create space in negotiation processes, where stakeholders often have competing claims on natural resources. Multiple

  14. Requirements for Control Room Computer-Based Procedures for use in Hybrid Control Rooms

    Energy Technology Data Exchange (ETDEWEB)

    Le Blanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States); Oxstrand, Johanna Helene [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey Clark [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-05-01

    Many plants in the U.S. are currently undergoing control room modernization. The main drivers for modernization are the aging and obsolescence of existing equipment, which typically results in a like-for-like replacement of analogue equipment with digital systems. However, the modernization efforts present an opportunity to employ advanced technology that would not only extend the life, but enhance the efficiency and cost competitiveness of nuclear power. Computer-based procedures (CBPs) are one example of near-term advanced technology that may provide enhanced efficiencies above and beyond like for like replacements of analog systems. Researchers in the LWRS program are investigating the benefits of advanced technologies such as CBPs, with the goal of assisting utilities in decision making during modernization projects. This report will describe the existing research on CBPs, discuss the unique issues related to using CBPs in hybrid control rooms (i.e., partially modernized analog control rooms), and define the requirements of CBPs for hybrid control rooms.

  15. Indiana Air Pollution Control Board Approves a Modification on a PSD Permit for General Motors in which Two Coal-Fired Boilers are Forgiven a SO2 Control Requirement

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. Magnetocardiography and magnetoencephalography measurements at room temperature using tunnel magneto-resistance sensors

    Science.gov (United States)

    Fujiwara, Kosuke; Oogane, Mikihiko; Kanno, Akitake; Imada, Masahiro; Jono, Junichi; Terauchi, Takashi; Okuno, Tetsuo; Aritomi, Yuuji; Morikawa, Masahiro; Tsuchida, Masaaki; Nakasato, Nobukazu; Ando, Yasuo

    2018-02-01

    Magnetocardiography (MCG) and magnetoencephalography (MEG) signals were detected at room temperature using tunnel magneto-resistance (TMR) sensors. TMR sensors developed with low-noise amplifier circuits detected the MCG R wave without averaging, and the QRS complex was clearly observed with averaging at a high signal-to-noise ratio. Spatial mapping of the MCG was also achieved. Averaging of MEG signals triggered by electroencephalography (EEG) clearly observed the phase inversion of the alpha rhythm with a correlation coefficient as high as 0.7 between EEG and MEG.

  17. Effects of living room, Snoezelen room, and outdoor activities on stereotypic behavior and engagement by adults with profound mental retardation.

    Science.gov (United States)

    Cuvo, A J; May, M E; Post, T M

    2001-01-01

    Two experiments were conducted to test the effect of a room with sensory equipment, or Snoezelen room, on the stereotypic behavior and engagement of adults with profound mental retardation. In Experiment 1, participants were observed in their living room before and after attending the Snoezelen room. Results showed that there tended to be a reduction in stereotypy and increase in engagement when participants went from their living room to the Snoezelen room, and a return of these behaviors to pre-Snoezelen levels in the living room. Positive effects in the Snoezelen room did not carryover to the living room. In Experiment 2, the living and Snoezelen rooms were compared to an outdoor activity condition with the same participants and target behaviors. Results showed that the outdoor condition was superior, the Snoezelen condition intermediate, and the living room least effective in their impact on stereotypic behavior and engagement. Conceptualizations regarding factors that maintain stereotypic behavior and engagement were discussed in the context of the three experimental conditions.

  18. Mapping the Heart

    Science.gov (United States)

    Hulse, Grace

    2012-01-01

    In this article, the author describes how her fourth graders made ceramic heart maps. The impetus for this project came from reading "My Map Book" by Sara Fanelli. This book is a collection of quirky, hand-drawn and collaged maps that diagram a child's world. There are maps of her stomach, her day, her family, and her heart, among others. The…

  19. USGS Map Indices Overlay Map Service from The National Map

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The USGS Map Indices service from The National Map (TNM) consists of 1x1 Degree, 30x60 Minute (100K), 15 Minute (63K), 7.5 Minute (24K), and 3.75 Minute grid...

  20. Applicability of vulnerability maps

    Energy Technology Data Exchange (ETDEWEB)

    Andersen, L.J.; Gosk, E. (Geological Survey of Denmark, Copenhagen (Denmark))

    A number of aspects to vulnerability maps are discussed: the vulnerability concept, mapping purposes, possible users, and applicability of vulnerability maps. Problems associated with general-type vulnerability mapping, including large-scale maps, universal pollutant, and universal pollution scenario are also discussed. An alternative approach to vulnerability assessment - specific vulnerability mapping for limited areas, specific pollutant, and predefined pollution scenario - is suggested. A simplification of the vulnerability concept is proposed in order to make vulnerability mapping more objective and by this means more comparable. An extension of the vulnerability concept to the rest of the hydrogeological cycle (lakes, rivers, and the sea) is proposed. Some recommendations regarding future activities are given.

  1. 7. Annex II: Maps

    OpenAIRE

    Aeberli, Annina

    2012-01-01

    Map 1: States of South Sudan UN OCHA (2012) Republic of South Sudan – States, as of 15 July 2012, Reliefweb http://reliefweb.int/map/south-sudan-republic/republic-south-sudan-states-15-july-2012-reference-map, accessed 31 July 2012. Map 2: Counties of South Sudan UN OCHA (2012) Republic of South Sudan – Counties, as of 16 July 2012, Reliefweb http://reliefweb.int/map/south-sudan-republic/republic-south-sudan-counties-16-july-2012-reference-map, accessed 31 July 2012. Map 3: Eastern Equato...

  2. An Ethogram to Quantify Operating Room Behavior

    Science.gov (United States)

    Jones, Laura K.; Jennings, Bonnie Mowinski; Goelz, Ryan M.; Haythorn, Kent W.; Zivot, Joel B.; de Waal, Frans B. M.

    2017-01-01

    Background The operating room (OR) is a highly social and hierarchical setting where interprofessional team members must work interdependently under pressure. Due primarily to methodological challenges, the social and behavioral sciences have had trouble offering insight into OR dynamics. Purpose We adopted a method from the field of ethology for observing and quantifying the interpersonal interactions of OR team members. Methods We created and refined an ethogram, a catalog of all our subjects’ observable social behaviors. The ethogram was then assessed for its feasibility and interobserver reliability. Results It was feasible to use an ethogram to gather data in the OR. The high interobserver reliability (Cohen’s Kappa coefficients of 81 % and higher) indicates its utility for yielding largely objective, descriptive, quantitative data on OR behavior. Conclusions The method we propose has potential for social research conducted in healthcare settings as complex as the OR. PMID:26813263

  3. Lean Strategies in the Operating Room.

    Science.gov (United States)

    Robinson, Stephen T; Kirsch, Jeffrey R

    2015-12-01

    Lean strategies can be readily applied to health care in general and operating rooms specifically. The emphasis is on the patient as the customer, respect and engagement of all providers, and leadership from management. The strategy of lean is to use continuous improvement to eliminate waste from the care process, leaving only value-added activities. This iterative process progressively adds the steps of identifying the 7 common forms of waste (transportation, inventory, motion, waiting, overproduction, overprocessing, and defects), 5S (sort, simplify, sweep, standardize, sustain), visual controls, just-in-time processing, level-loaded work, and built-in quality to achieve the highest quality of patient care. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. In the post-colonial waiting room

    DEFF Research Database (Denmark)

    Adler-Nissen, Rebecca; Gad, Ulrik Pram

    2017-01-01

    This chapter investigates this puzzle of choosing non-sovereignty in a postcolonial setting. Historically, the question of freedom from imperial hegemony has been linked to how Western colonialism involved keeping the colonized in ‘the waiting room of history’ by insisting that they were not yet...... ready for sovereignty. It explores a number of European overseas countries and territories. More specifically, it focuses on French dependencies in the Pacific and Indian Oceans, and North Atlantic Greenland constitutionally connected to Denmark. The immediate aim of anti-colonial struggles was to make...... acknowledge. A number of overseas territories take alternative routes to agency; not by resisting the norm of sovereignty - but by creatively articulating it beyond its claim to represent an 'either/or' distinction. The chapter demonstrates that territories not formally decolonized may very well perform...

  5. Computational Fluid Dynamics and Room Air Movement

    DEFF Research Database (Denmark)

    Nielsen, Peter Vilhelm

    2004-01-01

    on the mass fraction transport equation. The importance of ?false? or numerical diffusion is also addressed in connection with the simple description of a supply opening. The different aspects of boundary conditions in the indoor environment as e.g. the simulation of Air Terminal Devices and the simulation......Nielsen, P.V. Computational Fluid Dynamics and Room Air Movement. Indoor Air, International Journal of Indoor Environment and Health, Vol. 14, Supplement 7, pp. 134-143, 2004. ABSTRACT Computational Fluid Dynamics (CFD) and new developments of CFD in the indoor environment as well as quality...... considerations are important elements in the study of energy consumption, thermal comfort and indoor air quality in buildings. The paper discusses the quality level of Computational Fluid Dynamics and the involved schemes (first, second and third order schemes) by the use of the Smith and Hutton problem...

  6. [Controlling systems for operating room managers].

    Science.gov (United States)

    Schüpfer, G; Bauer, M; Scherzinger, B; Schleppers, A

    2005-08-01

    Management means developing, shaping and controlling of complex, productive and social systems. Therefore, operating room managers also need to develop basic skills in financial and managerial accounting as a basis for operative and strategic controlling which is an essential part of their work. A good measurement system should include financial and strategic concepts for market position, innovation performance, productivity, attractiveness, liquidity/cash flow and profitability. Since hospitals need to implement a strategy to reach their business objectives, the performance measurement system has to be individually adapted to the strategy of the hospital. In this respect the navigation system developed by Gälweiler is compared to the "balanced score card" system of Kaplan and Norton.

  7. Ethos and pathos in the delivery room.

    Science.gov (United States)

    Oliveira, Virgínia Junqueira; Penna, Claudia Maria de Mattos

    2017-07-06

    To understand the ethos and pathos in the discourses of pregnant women and healthcare professionals in the context of the delivery room. This is a qualitative and interpretative study. The research approach was discourse analysis. The study participants were 36 women and 24 health workers from seven maternity hospitals in midwestern Minas Gerais, Brazil. The discourses indicate the notion the women have of childbirth, centered in the eyes of others and in their representations. The nurses have difficulty operationalising care and building a professional image. The medical discourse stresses the skills, the ability to intervene in high-risk situations, and changes in the status of the profession. The construction of the ethos of physicians and nurses to essential to design more flexible fields of knowledge and ensure a professional performance that is consistent with their role, committed to the ethical and legal issues of obstetric care.

  8. HEMATOLOGIC FINDINGS IN OPERATING ROOM STAFFS

    Directory of Open Access Journals (Sweden)

    H SOLTANI

    2000-03-01

    Full Text Available Introduction. Long term exposure to trace amounts of anesthetic vapors and gases may produce hematologic and hepatic disorders in human. Since operating room (OR staffs are exposed to these agents, we decided to study their hematopoietic and hepatic systems in comparison with ordinary ward staffs. Methods. Seventy staffs from OR were compared with a matched similar number of ward staffs about their hematologic and hepatic laboratory findings in a historical cohort study. Findings. Mean of leukocyte and platelet counts were significantly lower in OR staffs, but in normal range. Mean of monocyte count was significantly higher in OR staffs. No significant differences were found between two groups for other hepatic and hematologic tests. Fatigue and headache were reported in OR staffs more than others. Conclusion. These findings may warn a risk to OR staffs but, it is not clear and requires further controlled studies.

  9. Physician communication in the operating room.

    Science.gov (United States)

    Kirschbaum, Kristin A; Rask, John P; Fortner, Sally A; Kulesher, Robert; Nelson, Michael T; Yen, Tony; Brennan, Matthew

    2015-01-01

    In this study, communication research was conducted with multidisciplinary groups of operating-room physicians. Theoretical frameworks from intercultural communication and rhetoric were used to (a) measure latent cultural communication variables and (b) conduct communication training with the physicians. A six-step protocol guided the research with teams of physicians from different surgical specialties: anesthesiologists, general surgeons, and obstetrician-gynecologists (n = 85). Latent cultural communication variables were measured by surveys administered to physicians before and after completion of the protocol. The centerpiece of the 2-hour research protocol was an instructional session that informed the surgical physicians about rhetorical choices that support participatory communication. Post-training results demonstrated scores increased on communication variables that contribute to collaborative communication and teamwork among the physicians. This study expands health communication research through application of combined intercultural and rhetorical frameworks, and establishes new ways communication theory can contribute to medical education.

  10. Efficiency of the operating room suite.

    Science.gov (United States)

    Weinbroum, Avi A; Ekstein, Perla; Ezri, Tiberiu

    2003-03-01

    The need to control high costs of running operating rooms while providing for timely patient care led us to assess the time wasted in the operating room (OR). OR use by two general surgery and two orthopedic departments in a metropolitan public hospital were analyzed, and the time elapsed when a scheduled OR remained unused or the patient was still awaiting surgery was measured. OR "time-waste" defined as the time in which the scheduled OR was not busy with the scheduled patient amounted to 79 hours over the 30-day study period (15% of total time). It was wasted owing to inappropriately prepared patients (12%), unavailability of surgeons (7%), insufficient nursing staff, anesthesiologists, or OR assignment to emergency surgery (59%), congestion of the postanesthesia care unit (10%), and delay in transport to the OR (2%) Another issue delineated was the frequent occurrence of surgical cases running longer than their scheduled time (termed "spill-over"), outrunning the staffing expectations after 3:00 PM and delaying admission of add-on and emergency procedures, adding 33% to the time wasted. A quality-assurance committee review resulted in implementation of new guidelines, and within 3 months several underlying causes were rectified, and time-waste and spill over time was reduced by 35%. Surgical time predictions were also improved. Shortage of nurses and anesthesiologists, and OR emergency reassignment remained the major causes of OR waste time. Continuous surveillance on OR suite-patients' prompt care, repeated evaluation, and wise staff deployment-could maximize OR efficiency.

  11. Designing an Alternate Mission Operations Control Room

    Science.gov (United States)

    Montgomery, Patty; Reeves, A. Scott

    2014-01-01

    The Huntsville Operations Support Center (HOSC) is a multi-project facility that is responsible for 24x7 real-time International Space Station (ISS) payload operations management, integration, and control and has the capability to support small satellite projects and will provide real-time support for SLS launches. The HOSC is a service-oriented/ highly available operations center for ISS payloads-directly supporting science teams across the world responsible for the payloads. The HOSC is required to endure an annual 2-day power outage event for facility preventive maintenance and safety inspection of the core electro-mechanical systems. While complete system shut-downs are against the grain of a highly available sub-system, the entire facility must be powered down for a weekend for environmental and safety purposes. The consequence of this ground system outage is far reaching: any science performed on ISS during this outage weekend is lost. Engineering efforts were focused to maximize the ISS investment by engineering a suitable solution capable of continuing HOSC services while supporting safety requirements. The HOSC Power Outage Contingency (HPOC) System is a physically diversified compliment of systems capable of providing identified real-time services for the duration of a planned power outage condition from an alternate control room. HPOC was designed to maintain ISS payload operations for approximately three continuous days during planned HOSC power outages and support a local Payload Operations Team, International Partners, as well as remote users from the alternate control room located in another building.

  12. Google Maps: You Are Here

    Science.gov (United States)

    Jacobsen, Mikael

    2008-01-01

    Librarians use online mapping services such as Google Maps, MapQuest, Yahoo Maps, and others to check traffic conditions, find local businesses, and provide directions. However, few libraries are using one of Google Maps most outstanding applications, My Maps, for the creation of enhanced and interactive multimedia maps. My Maps is a simple and…

  13. Mapping posttranscriptional modifications in 5S ribosomal RNA by MALDI mass spectrometry

    DEFF Research Database (Denmark)

    Kirpekar, F; Douthwaite, S; Roepstorff, P

    2000-01-01

    We present a method to screen RNA for posttranscriptional modifications based on Matrix Assisted Laser Desorption/Ionization mass spectrometry (MALDI-MS). After the RNA is digested to completion with a nucleotide-specific RNase, the fragments are analyzed by mass spectrometry. A comparison...... of the observed mass data with the data predicted from the gene sequence identifies fragments harboring modified nucleotides. Fragments larger than dinucleotides were valuable for the identification of posttranscriptional modifications. A more refined mapping of RNA modifications can be obtained by using two...... RNases in parallel combined with further fragmentation by Post Source Decay (PSD). This approach allows fast and sensitive screening of a purified RNA for posttranscriptional modification, and has been applied on 5S rRNA from two thermophilic microorganisms, the bacterium Bacillus stearothermophilus...

  14. Surgical attire and the operating room: role in infection prevention.

    Science.gov (United States)

    Salassa, Tiare E; Swiontkowski, Marc F

    2014-09-03

    ➤ Although there is some evidence that scrubs, masks, and head coverings reduce bacterial counts in the operating room, there is no evidence that these measures reduce the prevalence of surgical site infection.➤ The use of gloves and impervious surgical gowns in the operating room reduces the prevalence of surgical site infection.➤ Operating-room ventilation plays an unclear role in the prevention of surgical site infection.➤ Exposure of fluids and surgical instruments to the operating-room environment can lead to contamination. Room traffic increases levels of bacteria in the operating room, although the role of this contamination in surgical site infection is unclear. Copyright © 2014 by The Journal of Bone and Joint Surgery, Incorporated.

  15. Risk maps for navigation in liver surgery

    Science.gov (United States)

    Hansen, C.; Zidowitz, S.; Schenk, A.; Oldhafer, K.-J.; Lang, H.; Peitgen, H.-O.

    2010-02-01

    The optimal transfer of preoperative planning data and risk evaluations to the operative site is challenging. A common practice is to use preoperative 3D planning models as a printout or as a presentation on a display. One important aspect is that these models were not developed to provide information in complex workspaces like the operating room. Our aim is to reduce the visual complexity of 3D planning models by mapping surgically relevant information onto a risk map. Therefore, we present methods for the identification and classification of critical anatomical structures in the proximity of a preoperatively planned resection surface. Shadow-like distance indicators are introduced to encode the distance from the resection surface to these critical structures on the risk map. In addition, contour lines are used to accentuate shape and spatial depth. The resulting visualization is clear and intuitive, allowing for a fast mental mapping of the current resection surface to the risk map. Preliminary evaluations by liver surgeons indicate that damage to risk structures may be prevented and patient safety may be enhanced using the proposed methods.

  16. Photographic art in exam rooms may reduce white coat hypertension.

    Science.gov (United States)

    Harper, Michael B; Kanayama-Trivedi, Stacy; Caldito, Gloria; Montgomery, David; Mayeaux, E J; DelRosso, Lourdes M

    2015-12-01

    Blood pressure (BP) elevation in medical office settings in patients who are normotensive in nonmedical settings is an effect known as 'white coat hypertension'. This phenomenon is thought to be due to situational anxiety caused by the experience of visiting a doctor and the anxiety-inducing nature of the medical office. Our study was designed to determine if carefully selected photographic art could counter the anxiety that causes white coat hypertension and lead to lower BP recordings in some patients. 117 adults, non-pregnant patients from the Louisiana State University Health Sciences Center Family Medicine Resident Clinic participated in this study. After the triage nurse measured the BP, the patients were randomly placed in either an exam room with standard medical posters (control room) or in an exam room with photographic art (photo room). The BP was measured in the exam room. After the medical visit, the patients switched rooms and the BP was measured a third time. The patients were asked to fill out a questionnaire to identify room preference. On average, the BP obtained in the control rooms was higher than that obtained in the photo rooms. There was a statistically significant difference between the mean arterial pressure, systolic BP and diastolic BP between the control room and the photo room. Landscape photographic art may have the beneficial effect of reducing BP in medical office examination rooms. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  17. Sequential Organization and Room Reverberation for Speech Segregation

    Science.gov (United States)

    2012-02-28

    rooms. Wechoose two acoustic rooms with the reverberation time (T^)) equal to 0.3 and 0.5 s, respectively. In each room, two RIRs corresponding to...Labeling accuracy of the proposed and comparison systems shown as a function of reverberation time for (a) two-talker and (b) three-talker mixtures...of reverberation time . This sequential organization approach was published in a 2010 paper by J. Woodruff and D.L. Wang, entitled ’’Sequential

  18. Low-cost acoustic design of a bat test room

    OpenAIRE

    Correia, R.; Faneca, C.; Albuquerque, D.; Vieira, J.; Bastos, C.; Fonseca, C.; Ramos Pereira, M. J.

    2015-01-01

    Experiments with captive bats need a flight room that is acoustically neutral, especially when recording and analysing bat calls or the response of bats to certain sound stimuli. Our aim was to identify an isolation material with the best quality–price relationship to acoustically coat such a flight room. For this, we built a flight room divided into two compartments that were to be acoustically isolated from one another. Audible and infrasonic waves are difficult to attenuate ...

  19. Contaminant Distribution Around Persons in Rooms Ventilated by Displacement Ventilation

    DEFF Research Database (Denmark)

    Brohus, Henrik; Nielsen, Peter V.

    An optimal design of the ventilation system needs a proper prediction of the velocity, temperature and contaminant distribution in the room. Traditionally this is done either by the use of simplified models or by a somewhat more comprehensive CFD-simulation. Common to both methods is usually the ...... the lack of consideration for the persons present in the room. This paper deals with some of the effects of persons present in a displacement ventilated room, especially the effect on the contaminant distribution....

  20. Quality of sound in large rooms: Alteration of room impulse responses

    Science.gov (United States)

    Linusson, Per

    1993-02-01

    Psychoacoustic testing of Room Impulse Responses (RIR), using editing techniques and listening tests with help of auralization is considered. Using these techniques the question of when the reverberation tail is subjectively diffuse was studied. This question is of great interest, for example for auralization techniques. Binaural Room Impulse Responses (BRIR's) were measured in two positions in a concert hall. Their respective reverberation tails were substituted by editing. Listening tests indicated that even with a connection time of 400 ms, some test persons could consistently detect differences with speech as source signal. With music (piano) as source signal the 'limit' of the diffuse part was somewhere between 200 to 400 ms. In the second listening test an individual reflection was substituted with a diffuse one by editing. Three types of diffuse reflections were used. The results indicated that it is possible to improve the subjective quality with a diffuse reflection. Furthermore the character of the diffuse reflection is significant.

  1. Expanding Thurston maps

    CERN Document Server

    Bonk, Mario

    2017-01-01

    This monograph is devoted to the study of the dynamics of expanding Thurston maps under iteration. A Thurston map is a branched covering map on a two-dimensional topological sphere such that each critical point of the map has a finite orbit under iteration. It is called expanding if, roughly speaking, preimages of a fine open cover of the underlying sphere under iterates of the map become finer and finer as the order of the iterate increases. Every expanding Thurston map gives rise to a fractal space, called its visual sphere. Many dynamical properties of the map are encoded in the geometry of this visual sphere. For example, an expanding Thurston map is topologically conjugate to a rational map if and only if its visual sphere is quasisymmetrically equivalent to the Riemann sphere. This relation between dynamics and fractal geometry is the main focus for the investigations in this work.

  2. Experimental and numerical comparison of absorption optimization in small rooms

    DEFF Research Database (Denmark)

    Wincentz, Jakob Nygård; Garcia, Julian Martinez-Villalba; Jeong, Cheol-Ho

    2016-01-01

    A vast majority of modern music is recorded and produced in small control room environments of volumes of around 50 m3 . Several problems occur when controlling the room acoustics of such small spaces. First, the room modes will produce strong peaks and dips particularly at lower frequencies......, boundary conditions, and phase information providing accuracy at low frequencies. Good agreements are found between measurements and simulations, confirming that FEM can be used as a design tool for optimizing absorption and acoustic parameters in small rooms...

  3. Fostering the practice of rooming-in in newborn care

    OpenAIRE

    Shrivastava, Saurabh R.; Shrivastava, Prateek S.; Jegadeesh Ramasamy

    2013-01-01

    Practice of rooming-in meant that baby and mother stayed together in the same room day and night in the hospital, right from the time of delivery till the time of discharge. Adoption of rooming-in offers multiple benefits to the newborn, mother, and mother-child as a unit. It is a cost-effective approach wherefewer instruments are required and spares additional manpower. Rooming-in endeavors the opportunity to contribute signifi cantly in the child’s growth, development and survival by assist...

  4. The Czech Tea Profession and the Phenomenon of Tea Rooms

    OpenAIRE

    Schröderová, Karolína

    2015-01-01

    In this bachelor thesis I have focused on the Czech tea culture and tea profession across tea rooms. I have dealt with influences that led to the present tea rooms' appearances. Furthermore I am dealing with ways of tea culture spreading, and what conduces to the tea room establishing. I am using the term of subculture in the connection with the tea culture, its meaning and position in the Czech culture. The main data source were semi- structured interviews with the tea rooms owners, all comp...

  5. Auditory virtual environment with dynamic room characteristics for music performances

    Science.gov (United States)

    Choi, Daniel Dhaham

    A room-adaptive system was designed to simulate an electro-acoustic space that changes room characteristics in real-time according to the content of sound. In this specific case, the focus of the sound components is on the different styles and genres of music. This system is composed of real-time music recognition algorithms that analyze the different elements of music, determine the desired room characteristics, and output the acoustical parameters via multi-channel room simulation mechanisms. The system modifies the acoustic properties of a space and enables it to "improvise" its acoustical parameters based on the sounds of the music performances.

  6. Sensory rooms in psychiatric inpatient care: Staff experiences.

    Science.gov (United States)

    Björkdahl, Anna; Perseius, Kent-Inge; Samuelsson, Mats; Lindberg, Mathilde Hedlund

    2016-10-01

    There is an increased interest in exploring the use of sensory rooms in psychiatric inpatient care. Sensory rooms can provide stimulation via sight, smell, hearing, touch and taste in a demand-free environment that is controlled by the patient. The rooms may reduce patients' distress and agitation, as well as rates of seclusion and restraint. Successful implementation of sensory rooms is influenced by the attitudes and approach of staff. This paper presents a study of the experiences of 126 staff members who worked with sensory rooms in a Swedish inpatient psychiatry setting. A cross-sectional descriptive survey design was used. Data were collected by a web based self-report 12-item questionnaire that included both open- and closed-ended questions. Our findings strengthen the results of previous research in this area in many ways. Content analyses revealed three main categories: hopes and concerns, focusing on patients' self-care, and the room as a sanctuary. Although staff initially described both negative and positive expectations of sensory rooms, after working with the rooms, there was a strong emphasis on more positive experiences, such as letting go of control and observing an increase in patients' self-confidence, emotional self-care and well-being. Our findings support the important principals of person-centred nursing and recovery-oriented mental health and the ability of staff to implement these principles by working with sensory rooms. © 2016 Australian College of Mental Health Nurses Inc.

  7. Foucault could have been an operating room nurse.

    Science.gov (United States)

    Riley, Robin; Manias, Elizabeth

    2002-08-01

    Operating room nursing is an under-researched area of nursing practice. The stereotypical image of operating room nursing is one of task- and technically-orientated aspects of practice, where nurses work in a medical model and are dominated by constraints from outside their sphere of influence. This paper explores the possibility of understanding operating room nursing in a different way. Using the work of Michel Foucault to analyse the work of operating room nursing, this paper argues the relevance of the framework for a more in-depth analysis of this specialty area of practice. The concepts of power, discipline and subjectivity are used to demonstrate how operating room nursing is constructed as a discipline and how operating room nurses act to govern and construct the specialty. Exemplars are drawn from extensive professional experience, from guidelines of professional operating room nursing associations, as well as published texts. The focus is predominantly on the regulation of space and time to maintain the integrity of the sterile surgical field and issues of management, as well as the use of the ethical concept of the 'surgical conscience'. This form of analysis provides a level and depth of inquiry that has rarely been undertaken in operating room nursing. As such, it has the potential to provide a much needed, different view of operation room nursing that can only help to strengthen its professional foundations and development.

  8. Equal autophonic level curves under different room acoustics conditions

    DEFF Research Database (Denmark)

    Pelegrin Garcia, David; Mendizábal, Oier Fuentes; Brunskog, Jonas

    2011-01-01

    The indirect auditory feedback from one’s own voice arises from sound reflections at the room boundaries or from sound reinforcement systems. The relative variations of indirect auditory feedback are quantified through room acoustic parameters such as the room gain and the voice support, rather...... curves. These curves give an indication of the amount of variation in voice level induced by the acoustic environment as a consequence of the sidetone compensation or Lombard effect. In the range of typical rooms for speech, the variations in overall voice level that result in a constant autophonic level...

  9. Auditory display as feedback for a novel eye-tracking system for sterile operating room interaction.

    Science.gov (United States)

    Black, David; Unger, Michael; Fischer, Nele; Kikinis, Ron; Hahn, Horst; Neumuth, Thomas; Glaser, Bernhard

    2018-01-01

    The growing number of technical systems in the operating room has increased attention on developing touchless interaction methods for sterile conditions. However, touchless interaction paradigms lack the tactile feedback found in common input devices such as mice and keyboards. We propose a novel touchless eye-tracking interaction system with auditory display as a feedback method for completing typical operating room tasks. Auditory display provides feedback concerning the selected input into the eye-tracking system as well as a confirmation of the system response. An eye-tracking system with a novel auditory display using both earcons and parameter-mapping sonification was developed to allow touchless interaction for six typical scrub nurse tasks. An evaluation with novice participants compared auditory display with visual display with respect to reaction time and a series of subjective measures. When using auditory display to substitute for the lost tactile feedback during eye-tracking interaction, participants exhibit reduced reaction time compared to using visual-only display. In addition, the auditory feedback led to lower subjective workload and higher usefulness and system acceptance ratings. Due to the absence of tactile feedback for eye-tracking and other touchless interaction methods, auditory display is shown to be a useful and necessary addition to new interaction concepts for the sterile operating room, reducing reaction times while improving subjective measures, including usefulness, user satisfaction, and cognitive workload.

  10. Mapping in the cloud

    CERN Document Server

    Peterson, Michael P

    2014-01-01

    This engaging text provides a solid introduction to mapmaking in the era of cloud computing. It takes students through both the concepts and technology of modern cartography, geographic information systems (GIS), and Web-based mapping. Conceptual chapters delve into the meaning of maps and how they are developed, covering such topics as map layers, GIS tools, mobile mapping, and map animation. Methods chapters take a learn-by-doing approach to help students master application programming interfaces and build other technical skills for creating maps and making them available on the Internet. Th

  11. Mapping with Drupal

    CERN Document Server

    Palazzolo, Alan

    2011-01-01

    Build beautiful interactive maps on your Drupal website, and tell engaging visual stories with your data. This concise guide shows you how to create custom geographical maps from top to bottom, using Drupal 7 tools and out-of-the-box modules. You'll learn how mapping works in Drupal, with examples on how to use intuitive interfaces to map local events, businesses, groups, and other custom data. Although building maps with Drupal can be tricky, this book helps you navigate the system's complexities for creating sophisticated maps that match your site design. Get the knowledge and tools you ne

  12. Learning indoor robot navigation using visual and sensorimotor map information

    Science.gov (United States)

    Yan, Wenjie; Weber, Cornelius; Wermter, Stefan

    2013-01-01

    As a fundamental research topic, autonomous indoor robot navigation continues to be a challenge in unconstrained real-world indoor environments. Although many models for map-building and planning exist, it is difficult to integrate them due to the high amount of noise, dynamics, and complexity. Addressing this challenge, this paper describes a neural model for environment mapping and robot navigation based on learning spatial knowledge. Considering that a person typically moves within a room without colliding with objects, this model learns the spatial knowledge by observing the person's movement using a ceiling-mounted camera. A robot can plan and navigate to any given position in the room based on the acquired map, and adapt it based on having identified possible obstacles. In addition, salient visual features are learned and stored in the map during navigation. This anchoring of visual features in the map enables the robot to find and navigate to a target object by showing an image of it. We implement this model on a humanoid robot and tests are conducted in a home-like environment. Results of our experiments show that the learned sensorimotor map masters complex navigation tasks. PMID:24109451

  13. Human reliability analysis of control room operators

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac J.A.L.; Carvalho, Paulo Victor R.; Grecco, Claudio H.S. [Instituto de Engenharia Nuclear (IEN), Rio de Janeiro, RJ (Brazil)

    2005-07-01

    Human reliability is the probability that a person correctly performs some system required action in a required time period and performs no extraneous action that can degrade the system Human reliability analysis (HRA) is the analysis, prediction and evaluation of work-oriented human performance using some indices as human error likelihood and probability of task accomplishment. Significant progress has been made in the HRA field during the last years, mainly in nuclear area. Some first-generation HRA methods were developed, as THERP (Technique for human error rate prediction). Now, an array of called second-generation methods are emerging as alternatives, for instance ATHEANA (A Technique for human event analysis). The ergonomics approach has as tool the ergonomic work analysis. It focus on the study of operator's activities in physical and mental form, considering at the same time the observed characteristics of operator and the elements of the work environment as they are presented to and perceived by the operators. The aim of this paper is to propose a methodology to analyze the human reliability of the operators of industrial plant control room, using a framework that includes the approach used by ATHEANA, THERP and the work ergonomics analysis. (author)

  14. B-Target Room Tunnel Redesigned

    Energy Technology Data Exchange (ETDEWEB)

    Esfandiari, Reza; /San Jose State U. /SLAC

    2010-08-25

    Several groups at SLAC National Accelerator Laboratory are currently working on a RF Modulator prototype for a future linear collider known as the International Linear Collider (ILC). The ILC runs using about a 1000 Klystrons which create high power carrier waves for the particle acceleration. Klystrons receive their electrical input power from modulators. In order to move beyond the prototype phase, the laboratory might expand its ground base further down a tunnel located at the End Station B (ESB) in order to house four new Klystron Modulator Test Stations. This area is known as the B-Target Room Tunnel, and the task was to redesign the tunnel layout for the upcoming changes. The project first began by collecting substantial amount of information about the prototyped project, the tunnel and the researchers feedback of what they would like to see in the upcoming design. Subsequent to numerous planning and presentations, one particular design was. Calculations for this design were then performed for the most complex aspects of the project. Based on the results of the calculations, specific sample beams, welds, bolts and materials were chosen for the possible future construction.

  15. Display of information in the operating room.

    Science.gov (United States)

    Kiefer, Nicholas; Hoeft, Andreas

    2010-12-01

    The ongoing development of new sensors and parameters for intraoperative monitoring has outpaced the development of display design, leading to a gap between the load of information and the quality of its delivery. This is not a circumstantial problem, as a large portion of critical incidents is attributable to inadequate situation awareness and the failure to recognize readily monitored data. This review also addresses improvements of current threshold alarms. Research has focused on advanced integrated displays, drawing on the findings of human factor science and on the exploitation of alternative sensory pathways. Integrated displays, as well as auditory, vibrotactile and head-mounted displays have been shown to promote situation awareness and reduce cognitive workload. Intelligent alarm design can successfully reduce the number of false alarms. Improvement of the display of information in the operating room is warranted, and recent developments are promising. However, their introduction into mass market is not yet on the horizon, although the shortcomings of the traditional single-sensor-single-indicator principle are known for a long time. If manufacturers are reluctant to implement new techniques into their devices, they should at least facilitate access to monitoring raw data in order to allow independent development of displays.

  16. Titanium nitride room-temperature ferromagnetic nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Morozov, Iu.G., E-mail: morozov@ism.ac.ru [Institute of Structural Macrokinetics and Materials Science, Russian Academy of Sciences, 8 Academician Osipyan Street, Chernogolovka, Moscow Region, 142432 (Russian Federation); Belousova, O.V. [Institute of Structural Macrokinetics and Materials Science, Russian Academy of Sciences, 8 Academician Osipyan Street, Chernogolovka, Moscow Region, 142432 (Russian Federation); Belyakov, O.A. [Ogarev Mordovia State University, Saransk, 68 Bol' shevistskaya Street, 430005 (Russian Federation); Parkin, I.P., E-mail: i.p.parkin@ucl.ac.uk [Department of Chemistry, Materials Chemistry Research Centre, University College London, 20 Gordon Street, London, WC1H 0AJ (United Kingdom); Sathasivam, S. [Department of Chemistry, Materials Chemistry Research Centre, University College London, 20 Gordon Street, London, WC1H 0AJ (United Kingdom); Kuznetcov, M.V., E-mail: maxim1968@mail.ru [All-Russian Research Institute on Problems of Civil Defense and Emergencies of Emergency Control Ministry of Russia (EMERCOM), 7 Davidkovskaya Street, Moscow, 121352 (Russian Federation)

    2016-08-05

    Cubic and near-spherical TiN nanoparticles ranging in average size from 20 to 125 nm were prepared by levitation-jet aerosol synthesis through condensation of titanium vapor in an inert gas flow with gaseous nitrogen injection. The nanoparticles were characterized by using scanning electron microscopy (SEM), X-ray diffraction (XRD), BET measurements, UV–Vis, FT-IR, Raman spectroscopy, XPS, and vibrating-sample magnetometry. Room-temperature ferromagnetism with maximum magnetization up to 2.5 emu/g was recorded for the nanoparticles. The results indicate that the observed ferromagnetic ordering was related to the defect Ti–N structures on the surface of nanoparticles. This suggestion is in good correlation with the measured spectroscopical data. - Highlights: • Levitation-jet aerosol synthesis of TiN nanoparticles (NPs). • SEM, XRD, BET, UV–vis, FT-IR, Raman, XPS and magnetic characterization of the NPs. • Correlation between optical and XPS measurements data and maximum magnetization of the NPs.

  17. Safety status system for operating room devices.

    Science.gov (United States)

    Guédon, Annetje C P; Wauben, Linda S G L; Overvelde, Marlies; Blok, Joleen H; van der Elst, Maarten; Dankelman, Jenny; van den Dobbelsteen, John J

    2014-01-01

    Since the increase of the number of technological aids in the operating room (OR), equipment-related incidents have come to be a common kind of adverse events. This underlines the importance of adequate equipment management to improve the safety in the OR. A system was developed to monitor the safety status (periodic maintenance and registered malfunctions) of OR devices and to facilitate the notification of malfunctions. The objective was to assess whether the system is suitable for use in an busy OR setting and to analyse its effect on the notification of malfunctions. The system checks automatically the safety status of OR devices through constant communication with the technical facility management system, informs the OR staff real-time and facilitates notification of malfunctions. The system was tested for a pilot period of six months in four ORs of a Dutch teaching hospital and 17 users were interviewed on the usability of the system. The users provided positive feedback on the usability. For 86.6% of total time, the localisation of OR devices was accurate. 62 malfunctions of OR devices were reported, an increase of 12 notifications compared to the previous year. The safety status system was suitable for an OR complex, both from a usability and technical point of view, and an increase of reported malfunctions was observed. The system eases monitoring the safety status of equipment and is a promising tool to improve the safety related to OR devices.

  18. Integrated intra-operative room design.

    Science.gov (United States)

    Ng, Ivan

    2011-01-01

    The design of intraoperative suites require significant inputs from the neurosurgeons. Prior consideration of specific surgical objectives before investment of capital resources will enable to surgeon to yield maximum value from the project. We describe the setup of the integrated neurosurgical centre at our institution which comprises of a hybrid high field MRI suite, an OR's consisting of a multi-slice CT scanner and iso-C 3D respectively. The iCT and ioMRI OR's carry ICG angiography capabilities. These ORs are linked to also the Novalis radiosurgery suites and outpatient clinics and offices to facilitate pre-surgical review, planning as well as treatment plans on a common interface via the BRAINSUITE net.Design considerations include right sit-ing of imaging equipment as well as a focus of ergonomics and design features to maximize workflow. Whenever possible, standard neurosurgical instrumentation is utilized. With widespread availability of technology, neuro-imaging in the operating room may become more prevalent. The surgeon is the lead individual in the team with regards to planning and designing the ORs to accommodate the new imaging equipment.

  19. Web Based Room Monitoring System Using Webcam

    Directory of Open Access Journals (Sweden)

    Tole Sutikno

    2008-04-01

    Full Text Available A security has become very important along with the increasing number of crime cases. If some security system fails, there is a need for a mechanism that capable in recording the criminal act. Therefore, it can be used for investigation purpose of the authorities. The objective of this research is to develop a security system using video streaming that able to monitor in real-time manner, display movies in a browser, and record a video as triggered by a sensor. This monitoring system comprises of two security level camera as a video recorder of special events based on infrared sensor that is connected to a microcontroller via serial communication and camera as a real-time room monitor. The hardware system consists of infrared sensor circuit to detect special events that is serially communicated to an AT89S51 microcontroller that controls the system to perform recording process, and the software system consists of a server that displaying video streaming in a webpage and a video recorder. The software for video recording and server camera uses Visual Basic 6.0 and for video streaming uses PHP 5.1.6. As the result, the system can be used to record special events that it is wanted, and can displayed video streaming in a webpage using LAN infrastructure.

  20. Active low frequency sound field control in a listening room using CABS (Controlled Acoustic Bass System) will also reduce the sound transmitted to neighbour rooms

    DEFF Research Database (Denmark)

    Nielsen, Sofus Birkedal; Celestinos, Adrian

    2012-01-01

    is possible at modal frequencies. For that reason the modal frequencies in the source room will also have big impact on the transmission to neighbour rooms. These low frequency resonance frequencies are very audible in the source room but also in neighbour rooms as a booming bass. CABS (Controlled Acoustic......Sound in rooms and transmission of sound between rooms gives the biggest problems at low frequencies. Rooms with rectangular boundaries have strong resonance frequencies and will give big spatial variations in sound pressure level (SPL) in the source room, and an increase in SPL of 20 dB at a wall...... Bass System) is a time based room correction system for reproduced sound using loudspeakers. The system can remove room modes at low frequencies, by active cancelling the reflection from at the rear wall to a normal stereo setup. Measurements in a source room using CABS and in two neighbour rooms have...

  1. NAIP Status Maps Gallery

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — NAIP Status Maps Gallery. These maps illustrate what aerial imagery collection is planned, whats been collected, when it is available and how it is available. These...

  2. Recovery Action Mapping Tool

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Recovery Action Mapping Tool is a web map that allows users to visually interact with and query actions that were developed to recover species listed under the...

  3. Mapping Medicare Disparities Tool

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CMS Office of Minority Health has designed an interactive map, the Mapping Medicare Disparities Tool, to identify areas of disparities between subgroups of...

  4. MapBook

    Data.gov (United States)

    National Aeronautics and Space Administration — Beginning with the systematic mapping of the lunar surface more than three decades ago, this database contains over 1600 maps of the planets and satellites of the...

  5. Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  6. RadMap

    Science.gov (United States)

    RadMap is an interactive desktop tool featuring a nationwide geographic information systems (GIS) map of long-term radiation monitoring locations across the United States with access to key information about the monitor and the area surrounding it.

  7. NGS Survey Control Map

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NGS Survey Control Map provides a map of the US which allows you to find and display geodetic survey control points stored in the database of the National...

  8. Obesity Prevalence Maps

    Science.gov (United States)

    ... to Prevent Obesity Early Care and Education State Indicator Report Salad Bars to School Healthy Food Service ... Statistics Adult Obesity Facts Childhood Obesity Facts Data, Trends and Maps Adult Obesity Maps Surveillance Systems Resources & ...

  9. Active Fire Mapping Program

    Science.gov (United States)

    Active Fire Mapping Program Current Large Incidents (Home) New Large Incidents Fire Detection Maps MODIS Satellite Imagery VIIRS Satellite Imagery Fire Detection GIS Data Fire Data in Google Earth ...

  10. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    1999-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...... set. Particular studies are made of branched polynomial covering maps arising from Riemann surfaces and from knots in the 3-sphere....

  11. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    2002-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...... set. Particular studies are made of branched polynomial covering maps arising from Riemann surfaces and from knots in the 3-sphere. (C) 2001 Elsevier Science B.V. All rights reserved....

  12. Diagnostic dilemmas in Alzheimer's disease: Room for shared decision making

    NARCIS (Netherlands)

    van der Flier, Wiesje M.; Kunneman, Marleen; Bouwman, Femke H.; Petersen, Ronald C.; Smets, Ellen M. A.

    2017-01-01

    The launch of the NIA-AA research criteria for Alzheimer's disease (AD) diagnosis illustrates the large advances that have been made in the field of AD diagnosis. These new possibilities however also introduce new dilemmas into the consulting room, and this provides room for shared decision making

  13. The Dress Room: responsive spaces and embodied interaction

    DEFF Research Database (Denmark)

    Vallgårda, Anna

    2014-01-01

    the qualities of responsive spaces and embodied interaction. The Dress Room is a white cube that responds to the body’s movements over the floor. The walls move, the room collapses or expands. I rely on a dancer to open up this experience. The outcome suggests that interacting with responsive environments can...

  14. TOF Imaging in Smart Room Environments towards Improved People Tracking

    DEFF Research Database (Denmark)

    Guðmundsson, Sigurjón Árni; Larsen, Rasmus; Aanæs, Henrik

    2008-01-01

    In this Paper we present the use of Time-of-Flight (TOF) cameras in Smart-rooms and how this leads to improved results in segmenting the people in the room from the background and consequently better 3D reconstruction of the people. A calibrated rig of one Swissranger SR3100 Time-of-flight range ...

  15. The Patient Safety Attitudes among the Operating Room Personnel

    Directory of Open Access Journals (Sweden)

    Cherdsak Iramaneerat

    2016-07-01

    Full Text Available Background: The first step in cultivating the culture of safety in the operating room is the assessment of safety culture among operating room personnel. Objective: To assess the patient safety culture of operating room personnel at the Department of Surgery, Faculty of Medicine Siriraj Hospital, and compare attitudes among different groups of personnel, and compare them with the international standards. Methods: We conducted a cross-sectional survey of safety attitudes among 396 operating room personnel, using a short form of the Safety Attitudes Questionnaire (SAQ. The SAQ employed 30 items to assess safety culture in six dimensions: teamwork climate, safety climate, stress recognition, perception of hospital management, working conditions, and job satisfaction. The subscore of each dimension was calculated and converted to a scale score with a full score of 100, where higher scores indicated better safety attitudes. Results: The response rate was 66.4%. The overall safety culture score of the operating room personnel was 65.02, higher than an international average (61.80. Operating room personnel at Siriraj Hospital had safety attitudes in teamwork climate, safety climate, and stress recognition lower than the international average, but had safety attitudes in the perception of hospital management, working conditions, and job satisfaction higher than the international average. Conclusion: The safety culture attitudes of operating room personnel at the Department of Surgery, Siriraj Hospital were comparable to international standards. The safety dimensions that Siriraj Hospital operating room should try to improve were teamwork climate, safety climate, and stress recognition.

  16. Relationship between room shape and acoustics of rectangular concert halls

    DEFF Research Database (Denmark)

    Klosak, Andrzej K.; Gade, Anders Christian

    2008-01-01

    Extensive acoustics computer simulations have been made using Odeon computer simulation software. In 24 rectangular rooms representing "shoe-box" type concert halls with volumes of 8 000 m3, 12 000 m3 and 16 000 m3 from 300 to 850 measurements positions have been analysed. Only room averaged...

  17. 9 CFR 354.241 - Cleaning of rooms and compartments.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Cleaning of rooms and compartments. 354.241 Section 354.241 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... Sanitary Conditions and Precautions Against Contamination of Products § 354.241 Cleaning of rooms and...

  18. 32 CFR 552.118 - Issuance from unit arms room.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Issuance from unit arms room. 552.118 Section 552... AND NATIONAL CEMETERIES REGULATIONS AFFECTING MILITARY RESERVATIONS Physical Security of Arms, Ammunition, and Explosives-Fort Lewis, Washington § 552.118 Issuance from unit arms room. When privately...

  19. 28 CFR 16.2 - Public reading rooms.

    Science.gov (United States)

    2010-07-01

    ... Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION... quarterly, with respect to newly included records. (b) The Department maintains public reading rooms or... Naturalization Service—425 I Street, NW., Washington, DC; (9) Office of Justice Programs—in Room 5430, 810...

  20. Plane Stratified Flow in a Room Ventilated by Displacement Ventilation

    DEFF Research Database (Denmark)

    Nielsen, Peter Vilhelm; Nickel, J.; Baron, D. J. G.

    2004-01-01

    The air movement in the occupied zone of a room ventilated by displacement ventilation exists as a stratified flow along the floor. This flow can be radial or plane according to the number of wall-mounted diffusers and the room geometry. The paper addresses the situations where plane flow...

  1. Loudspeaker-based room auralization in auditory perception research

    DEFF Research Database (Denmark)

    Buchholz, Jörg; Favrot, Sylvain Emmanuel

    2010-01-01

    Recently a loudspeaker-based room auralisation (LoRA) system has been developed at CAHR, which combines modern room acoustic modeling techniques with high-order Ambisonics auralisation. The environment provides: (i) a flexible research tool to study the signal processing of the normal, impaired, ...

  2. 33 CFR 52.81 - Reading room and index.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Reading room and index. 52.81... FOR CORRECTION OF MILITARY RECORDS OF THE COAST GUARD Public Access to Decisions § 52.81 Reading room and index. After deleting only so much personal information as is necessary to prevent an unwarranted...

  3. The Practice of Medicine at a District Hospital Emergency Room ...

    African Journals Online (AJOL)

    The Practice of Medicine at a District Hospital Emergency Room: Middelburg ... the doctors in the emergency room at a district hospital in an underserved area. ... with life-threatening and non-life-threatening conditions in the emergency ... In other words, the practitioner must have adequate diagnostic and therapeutic skills.

  4. Room acoustic analysis of blower unit and noise control plan in the typical steel industry

    Directory of Open Access Journals (Sweden)

    2013-02-01

    Full Text Available Introduction: In the steel industry,air blowers used to supply compressed air are considered as sources of annoying noise. This study aims to acoustics analysis of theairblower workroomand sound source characteristics in order to present noise controlmeasuresinthe steel industry. .Material and Method: Measurement of noiselevel and its frequency analysis was performed usingsound levelmetermodelof CASELLA-Cell.450. Distribution of noise level in the investigated workroom in form of noise map was provided using Surfer software. In addition, acoustic analysis of workroom and control room was performed in view point of soundabsorption andinsulation. Redesignofdoor and window of controlroom and installation of soundabsorbing materialson theceiling of the workroom were proposed and the efficiency of these interventionswasestimated. .Result: The totalsound pressurelevelin the blower workroom was 95.4 dB(L and the dominant frequency was 2000Hz. Sound pressure level inside the room control was 80.1dB(A. The average absorption coefficient and reverberation time in the blower workroom was estimated equal to 0.082 Sab.m2 and 3.9 seconds respectively. These value in control room was 0.04 Sab.m2 and 3/4 seconds respectively. In control room, sound transmission loss between the two parts of the wall dividing was 13.7 dB(A. The average of noise dose in blower operators was 230%. With the installation of sound absorber on ceiling of workroom, average of absorption coefficient can increase to 0.33 Sab.m2 and sound transmission loss of the new designed door and window was estimated equal to 20dB. . Conclusion: The main cause of noise leakage in the control room was insufficient insulation properties of door and windows. By replacing the door and window and installation of sound absorbing on ceiling of workroom, the noise dose can reduce to 49.6%. New Improved door and window of control room can reduce noise dose to 69.65% solely.

  5. Using maps in genealogy

    Science.gov (United States)

    ,

    1999-01-01

    Maps are one of many sources you may need to complete a family tree. In genealogical research, maps can provide clues to where our ancestors may have lived and where to look for written records about them. Beginners should master basic genealogical research techniques before starting to use topographic maps.

  6. Diffusion Based Photon Mapping

    DEFF Research Database (Denmark)

    Schjøth, Lars; Fogh Olsen, Ole; Sporring, Jon

    2007-01-01

    . To address this problem we introduce a novel photon mapping algorithm based on nonlinear anisotropic diffusion. Our algorithm adapts according to the structure of the photon map such that smoothing occurs along edges and structures and not across. In this way we preserve the important illumination features......, while eliminating noise. We call our method diffusion based photon mapping....

  7. On parabolic external maps

    DEFF Research Database (Denmark)

    Lomonaco, Luna; Petersen, Carsten Lunde; Shen, Weixiao

    2017-01-01

    We prove that any C1+BV degree d ≥ 2 circle covering h having all periodic orbits weakly expanding, is conjugate by a C1+BV diffeomorphism to a metrically expanding map. We use this to connect the space of parabolic external maps (coming from the theory of parabolic-like maps) to metrically...

  8. Mapping landscape corridors

    Science.gov (United States)

    Peter Vogt; Kurt H. Riitters; Marcin Iwanowski; Christine Estreguil; Jacek Kozak; Pierre Soille

    2007-01-01

    Corridors are important geographic features for biological conservation and biodiversity assessment. The identification and mapping of corridors is usually based on visual interpretations of movement patterns (functional corridors) or habitat maps (structural corridors). We present a method for automated corridor mapping with morphological image processing, and...

  9. Diffusion Based Photon Mapping

    DEFF Research Database (Denmark)

    Schjøth, Lars; Olsen, Ole Fogh; Sporring, Jon

    2006-01-01

    . To address this problem we introduce a novel photon mapping algorithm based on nonlinear anisotropic diffusion. Our algorithm adapts according to the structure of the photon map such that smoothing occurs along edges and structures and not across. In this way we preserve the important illumination features......, while eliminating noise. We call our method diffusion based photon mapping....

  10. Radiation Source Mapping with Bayesian Inverse Methods

    Science.gov (United States)

    Hykes, Joshua Michael

    We present a method to map the spectral and spatial distributions of radioactive sources using a small number of detectors. Locating and identifying radioactive materials is important for border monitoring, accounting for special nuclear material in processing facilities, and in clean-up operations. Most methods to analyze these problems make restrictive assumptions about the distribution of the source. In contrast, the source-mapping method presented here allows an arbitrary three-dimensional distribution in space and a flexible group and gamma peak distribution in energy. To apply the method, the system's geometry and materials must be known. A probabilistic Bayesian approach is used to solve the resulting inverse problem (IP) since the system of equations is ill-posed. The probabilistic approach also provides estimates of the confidence in the final source map prediction. A set of adjoint flux, discrete ordinates solutions, obtained in this work by the Denovo code, are required to efficiently compute detector responses from a candidate source distribution. These adjoint fluxes are then used to form the linear model to map the state space to the response space. The test for the method is simultaneously locating a set of 137Cs and 60Co gamma sources in an empty room. This test problem is solved using synthetic measurements generated by a Monte Carlo (MCNP) model and using experimental measurements that we collected for this purpose. With the synthetic data, the predicted source distributions identified the locations of the sources to within tens of centimeters, in a room with an approximately four-by-four meter floor plan. Most of the predicted source intensities were within a factor of ten of their true value. The chi-square value of the predicted source was within a factor of five from the expected value based on the number of measurements employed. With a favorable uniform initial guess, the predicted source map was nearly identical to the true distribution

  11. [Recovery Room. Organization and clinical aspects].

    Science.gov (United States)

    Leykin, Y; Costa, N; Gullo, A

    2001-01-01

    Correct administration in the early postoperative phase is decisive in the final outcome of surgery and the presence of the Recovery Room (RR) contributes significantly to a reduction in the post-operative risk rate. The objectives of the RR are: removal of the pharmacological effect of general anaesthesia; stabilization of vital parameters (circulation and ventilation); stabilization of body temperature; control of the hydro-electrolytic balance; intensive intervention in the case of an acute complication; prescribing a suitable postoperative analgesia; recovering movement in the case of loco-regional anesthesia. Organization of RR must take into consideration: 1) aspect of environment and location; 2) transport of the patient from the operating room to the RR; 3) definition of the equipment necessary for the RR; 4) definition of the role and qualification of the medical and nursing staff; 5) definition of regulations of assistance and the clinical file; 6) definition of criteria for discharge and transfer; 7) definition of means of adjournment, improvement and comparison with other similar structures. RR is administered by an Anesthetist with clinical, therapeutic and decision-making responsibility for the discharge of patients, while the supervision and assistance patients is entrusted to specialised professional nurses. From a clinical point of view the following data are monitored and recorded: the vital signs (passage of air-ways, cardiac and respiratory frequency, arterial pressure, saturation of O2, EtCO2 (in patient with air-way support), body temperature and the state of consciousness, instrumental monitoring of the patient (at pre-established time intervals), control of the skin, the peripheral circulation, surgical wounds, drainage and catheters. The percentage of incidence of complications in RR varies from 6-7 to 30% depending on various studies, probably in relation to the diversity of criteria in defining the complication. The principal

  12. Management of acute diarrhea in emergency room.

    Science.gov (United States)

    Dekate, Parag; Jayashree, M; Singhi, Sunit C

    2013-03-01

    Acute diarrhea is the second leading cause of under-five mortality in India. It is defined as the passage of frequent watery stools (>3/24 h). Recent change in consistency of stools is more important than frequency. Acute diarrhea is caused by variety of viral, bacterial and parasitic agents. The common ones are: Rotavirus, E. coli, Shigella, Cholera, and Salmonella. Campylobacter jejuni, Giardia and E. histolytica are also not uncommon. The most important concern in management of acute diarrhea in Emergency room (ER) is fluid and electrolyte imbalances and treatment of underlying infection, wherever applicable. It includes, initial stabilization (identification and treatment of shock), assessment of hydration and rehydration therapy, recognition and treatment of electrolyte imbalance, and use of appropriate antimicrobials wherever indicated. For assessment of hydration clinical signs are generally reliable; however, in severely malnourished children sunken eyes and skin turgor are unreliable. Oral Rehydration Therapy is the cornerstone of management of dehydration. Intravenous fluids are not routinely recommended except in cases of persistent vomiting and/or shock. Majority of cases can be managed in ER and at home. Hospitalization is indicated in infants <3 mo, children with severe dehydration, severe malnutrition, toxic look, persistent vomiting and suspected surgical abdomen. Supplementations with zinc and probiotics have been shown to reduce severity and duration of diarrhea; however evidence does not support the use of antisecretary, antimotility and binding agents. Education of parents about hand hygiene, safe weaning and safe drinking water etc., can help in reducing incidence of this important health problem in the country.

  13. Operating Room Fires in Oculoplastic Surgery.

    Science.gov (United States)

    Maamari, Robi N; Custer, Philip L

    2017-03-03

    This study was performed to characterize the frequency, causes, and possible risk factors of operating room (OR) fires experienced by members of the American Society of Ophthalmic Plastic and Reconstructive Surgery. An online questionnaire was distributed to American Society of Ophthalmic Plastic and Reconstructive Surgery members, collecting data on surgical fires experienced by respondents throughout their careers. In addition, the questionnaire investigated viewpoints on OR fire safety, current practice patterns with oxygen delivery and surgical device usage, and management of patients referred after previous surgical fire exposure. There were 258 participants in the survey. Eighty-three surgeons (32.2%) experienced at least 1 surgical fire in their careers. Most OR fires occurred during monitored sedation cases with oxygen delivered by nasal cannula underneath drapes completely covering the head and use of a monopolar or battery-operated device. Patient hair and skin were the most common fuel sources, and most of the injuries were limited to singing of facial hair. Regarding current practice patterns, monopolar, bipolar, and battery-powered disposable devices were the most frequently used electrosurgery and electrocautery tools. Patients seen after an OR fire with another surgeon generally experienced more severe burns requiring hospitalization and subsequent procedures. Many oculoplastic surgeons have experienced OR fires during their careers. Certain surgical and anesthetic techniques, particularly the delivery of supplemental oxygen underneath surgical drapes and the use of monopolar electrosurgery and battery-powered electrocautery, may be associated with increased fire risk. While most of the reported OR fires did not result in significant patient injury, caution must be taken to prevent these potentially devastating events.

  14. Surveillance of bacterial colonization in operating rooms.

    Science.gov (United States)

    Alexander, J Wesley; Van Sweringen, Heather; Vanoss, Katherine; Hooker, Edmond A; Edwards, Michael J

    2013-08-01

    Surgical site infections (SSIs) continue to occur at an unacceptably high rate, incurring direct costs of up to $10 billion per year in the United States and far more than that in total economic costs. There is a continued need to identify potential sources of microbial contamination that lead to surgical infections. Using contact culture plates, we randomly took a total of 517 samples of various surfaces in 33 operating rooms (ORs) over a 6-mo period. Flat surfaces treated with decontamination techniques (floors, anesthesia carts, operating tables, and other flat surfaces) grew small numbers of bacterial colonies, as did other surfaces that were decontaminated less often. Personal items, especially the tops of shoes and personal hats, had much higher contamination than the surfaces just described, which in the case of these two items averaged 50-60 CFU/20 cm(2). The outsides of face masks contained slightly more organisms than did floors, but the insides had almost 100 times more organisms, which was of concern because of high leakage rates at the mask-face interface. The culture system used in our study can be used as a simplified and cost-effective method of identifying the comparative densities of organisms on different surfaces for surveillance of microbial contamination in the OR. To reduce bacterial contamination, shoe covers and disposable hair coverings should be worn at every operation in which there are substantial risks of SSI. Masks that reduce leakage at the mask-face interface should be worn and discarded after each operation.

  15. TeamSTEPPS Improves Operating Room Efficiency and Patient Safety.

    Science.gov (United States)

    Weld, Lancaster R; Stringer, Matthew T; Ebertowski, James S; Baumgartner, Timothy S; Kasprenski, Matthew C; Kelley, Jeremy C; Cho, Doug S; Tieva, Erwin A; Novak, Thomas E

    2016-09-01

    The objective was to evaluate the effect of TeamSTEPPS on operating room efficiency and patient safety. TeamSTEPPS consisted of briefings attended by all health care personnel assigned to the specific operating room to discuss issues unique to each case scheduled for that day. The operative times, on-time start rates, and turnover times of all cases performed by the urology service during the initial year with TeamSTEPPS were compared to the prior year. Patient safety issues identified during postoperative briefings were analyzed. The mean case time was 12.7 minutes less with TeamSTEPPS (P room turnover time did not change. Patient safety issues declined from an initial rate of 16% to 6% at midyear and remained stable (P operating room efficiency and diminished patient safety issues in the operating room. © The Author(s) 2015.

  16. Fostering the practice of rooming-in in newborn care

    Directory of Open Access Journals (Sweden)

    Saurabh R. Shrivastava

    2013-09-01

    Full Text Available Practice of rooming-in meant that baby and mother stayed together in the same room day and night in the hospital, right from the time of delivery till the time of discharge. Adoption of rooming-in offers multiple benefits to the newborn, mother, and mother-child as a unit. It is a cost-effective approach wherefewer instruments are required and spares additional manpower. Rooming-in endeavors the opportunity to contribute signifi cantly in the child’s growth, development and survival by assisting in timely initiation of breastfeeding. To ensure universal application of rooming-in in hospitals, a comprehensive and technically sound strategy should be formulated and implemented with active participation of healthcare professionals. Measures such as advocating institutional delivery through outreach awareness activities; adoption of baby-friendly hospital initiative; inculcating a sense of ownership among health professionals, can be strategically enforced for better maternal and child health related outcomes.

  17. Overview of the LHD central control room data monitoring environment

    Energy Technology Data Exchange (ETDEWEB)

    Emoto, M., E-mail: emoto.masahiko@nifs.ac.jp; Yoshinuma, M.; Yoshida, M.; Nakanishi, H.; Iwata, C.; Ohsuna, M.; Nonomura, M.; Imazu, S.; Yokota, M.; Aoyagi, M.; Ogawa, H.; Ida, K.; Watanabe, K.; Kaneko, O.

    2016-11-15

    Highlights: • In this paper, the data monitoring environments in the LHD central control room, for example, summary data graph and video monitoring tools are introduced. Also, the environments for the remote participants are introduced. - Abstract: During the Large Helical Device (LHD) experiments, many scientists and technical staff are working in the central control room to operate the experiment. They must manage the diagnostics and controlling devices referring to the results of the last plasma shot. Also, the experiment coordinator must decide the conditions for the subsequent experiments using the results. Furthermore, many scientists are participating in the experiment from remote sites. Therefore, it is important to share the information in the control room quickly, such as the results of the last plasma discharge, with the remote user as well as with the staff in the room. In this paper, the data monitoring environment in the LHD central control room is introduced.

  18. LoRA: A Loudspeaker-Based Room Auralization System

    DEFF Research Database (Denmark)

    Favrot, Sylvain Emmanuel; Buchholz, Jörg

    2010-01-01

    that the involved signal processing preserves the temporal, spectral and spatial properties of the room impulse response captured by these parameters. This flexible research platform will be useful for studying auditory processing and perception in normal-hearing and hearing-impaired listeners in fully controlled......In order to study basic human perception in reverberant environments, a novel loudspeaker-based room auralization (LoRA) system is proposed in this paper. The LoRA system efficiently combines modern room acoustic models with high-order Ambisonic auralization. An objective evaluation has been...... carried out demonstrating the applicability of the LoRA system. Room acoustic parameters (reverberation time, clarity, speech transmission index and inter-aural cross correlation coefficients) of room impulse responses were compared at the input and the simulated output of the LoRA system. Results show...

  19. Air Distribution in Rooms with a Fan-Driven Convector

    DEFF Research Database (Denmark)

    Larsen, Tine Steen; Bindels, Rob H.W.; Michalak, Lukasz

    2007-01-01

    coming from the dijfuser is partly controlled by the momentum flow and partly from gravity forces, where the thermal load in the room and the temperature difference between room air and supply air affect the airflow from the convector. The convector system was tested in the same test room in which many......Experiments with a fan-driven convector used for both heating and cooling are de.scribed in this paper. Only the cooling situation is considered. The convector is positioned in the upper corner ofthe room, and from there the cold air is let out through the device along the ceiling. The airflow...... regular ventilation systems were tested earlier to be ahle to compare airflow from the convector .system with regular ventilation ,systems at a later stage of this research. The heat load in the room consists of a thermal manikin sitting at a desk, a computer, and a desk lamp producing a total heat load...

  20. Hospital Patient Room Design: The Issues Facing 23 Occupational Groups Who Work in Medical/Surgical Patient Rooms.

    Science.gov (United States)

    Lavender, Steven A; Sommerich, Carolyn M; Patterson, Emily S; Sanders, Elizabeth B-N; Evans, Kevin D; Park, Sanghyun; Umar, Radin Zaid Radin; Li, Jing

    2015-01-01

    The aim of this study was to learn from a wide range of hospital staff members about how the design of the patient room in which they work adversely affects their ergonomics or hinders their job performance. In addition to providing a healing space for patients, hospital patient rooms need to serve as functional workplaces for the people who provide clinical care, to clean, or to maintain room functions. Therefore, from a design perspective, it is important to understand the needs of all the users of hospital patient rooms with regard to room design. One hundred forty-seven people, representing 23 different occupational stakeholder groups, participated in either focus groups or interviews in which they were asked to identify room design issues that affect the performance of their work tasks. Key issues shared across multiple stakeholder groups included an inability to have eye contact with the patient when entering the room, inadequate space around the bed for the equipment used by stakeholders, the physical demands experienced as stakeholders move furnishings to accomplish their activities or access equipment, and a lack of available horizontal surfaces. Unique issues were also identified for a number of stakeholder groups. There are a number of issues that should be addressed in the next generation of hospital patient rooms, or when refurbishing existing facilities, so that all occupational stakeholder groups can work effectively, efficiently, and without undue physical stress. © The Author(s) 2015.

  1. Birth room images: what they tell us about childbirth. A discourse analysis of birth rooms in developed countries.

    Science.gov (United States)

    Bowden, Calida; Sheehan, Athena; Foureur, Maralyn

    2016-04-01

    this study examined images of birth rooms in developed countries to analyse the messages and visual discourse being communicated through images. a small qualitative study using Kress and van Leeuwen's (2006) social semiotic theoretical framework for image analysis, a form of discourse analysis. forty images of birth rooms were collected in 2013 from Google Images, Flickr, Wikimedia Commons and midwifery colleagues. The images were from obstetric units, alongside and freestanding midwifery units located in developed countries (Australia, Canada, Europe, New Zealand, United Kingdom and the United States of America). findings demonstrated three kinds of birth room images; the technological, the 'homelike', and the hybrid domesticated birth room. The most dominant was the technological birth room, with a focus on the labour bed and medical equipment. The visual messages from images of the technological birth room reinforce the notion that the bed is the most appropriate place to give birth and the use of medical equipment is intrinsically involved in the birth process. Childbirth is thus construed as risky/dangerous. as images on the Internet inform and persuade society about stereotypical behaviours, the trends of our time and sociocultural norms, it is important to recognise images of the technological birth room on the Internet may be influential in dictating women's attitudes, choices and behaviour, before they enter the birth room. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Geography Education Through Maps

    Directory of Open Access Journals (Sweden)

    N. Demiralp

    2007-09-01

    Full Text Available Geography studies the relationship between human and the earth and pay attention to space, place and environment. In its simplest definition, maps are language and communication tools in transferring knowledge of an area in the science of geography which studies the space. Thus teaching and teaching how to use maps is quite important. This is not valid just for all matters of geography education; they can be used at any point, level, age or grade in teaching. This is because map reading involves transferring a piece of information by coding it on a platform and the users to read and interpret the information by encoding it according to their needs. Thus, we can say that teaching maps and teaching how to use maps is the transformation or translation of a piece of knowledge from life, with the appropriate language. In order for this kind of teaching and learning to be accomplished it is a must that the map maker and the map user to know the common language of maps, which is map language, and for them to know qualities, types and limitations of maps. To gain this kind of knowledge, students must see every type of map from the simplest to the most complicated and study and analyse them, as well as get to know their different usages.

  3. Spatial Hearing with Incongruent Visual or Auditory Room Cues

    Science.gov (United States)

    Gil-Carvajal, Juan C.; Cubick, Jens; Santurette, Sébastien; Dau, Torsten

    2016-11-01

    In day-to-day life, humans usually perceive the location of sound sources as outside their heads. This externalized auditory spatial perception can be reproduced through headphones by recreating the sound pressure generated by the source at the listener’s eardrums. This requires the acoustical features of the recording environment and listener’s anatomy to be recorded at the listener’s ear canals. Although the resulting auditory images can be indistinguishable from real-world sources, their externalization may be less robust when the playback and recording environments differ. Here we tested whether a mismatch between playback and recording room reduces perceived distance, azimuthal direction, and compactness of the auditory image, and whether this is mostly due to incongruent auditory cues or to expectations generated from the visual impression of the room. Perceived distance ratings decreased significantly when collected in a more reverberant environment than the recording room, whereas azimuthal direction and compactness remained room independent. Moreover, modifying visual room-related cues had no effect on these three attributes, while incongruent auditory room-related cues between the recording and playback room did affect distance perception. Consequently, the external perception of virtual sounds depends on the degree of congruency between the acoustical features of the environment and the stimuli.

  4. Sound pressure level vs. distance from sources in rooms

    Energy Technology Data Exchange (ETDEWEB)

    Warnock, A.C.C. [National Research Council Canada, Ottawa, Ontario (Canada). Inst. for Research in Construction

    1998-10-01

    Sound fields in furnished rooms are not diffuse and so do not conform to diffuse-field theory. In an earlier ASHRAE research project, RP-339, sound pressure levels in a variety of normally furnished rooms were found to be reduced by 3 decibels each time the distance from the source was doubled. No dependence on room absorption was found. Under the conditions of the project reported here, RP-755, the reduction in level with increasing distance for a source in the room was found to depend on the inverse of the room reverberation time. The approximate relationship found was attenuation = 0.9/RT + 0.5 dB/distance doubling for 250 Hz and above. However, for furnished rooms, which are usually found to have reverberation times around 0.5 second, the attenuation is still very close to 3 dB per doubling of distance from the source, the value found in RP-339. When sources were in the plenum above the ceiling, the sound fields in the room below were, for practical purposes, uniform. Some attenuation was seen at 2 and 4 kHz, but it was small.

  5. Buoyancy driven acceleration in a hospital operating room indoor environment

    Science.gov (United States)

    McNeill, James; Hertzberg, Jean; Zhai, John

    2011-11-01

    In hospital operating rooms, centrally located non-isothermal ceiling jets provide sterile air for protecting the surgical site from infectious particles in the room air as well as room cooling. Modern operating rooms are requiring larger temperature differences to accommodate increasing cooling loads for heat gains from medical equipment. This trend may lead to significant changes in the room air distribution patterns that may sacrifice the sterile air field across the surgical table. Quantitative flow visualization experiments using laser sheet illumination and RANS modeling of the indoor environment were conducted to demonstrate the impact of the indoor environment thermal conditions on the room air distribution. The angle of the jet shear layer was studied as function of the area of the vena contracta of the jet, which is in turn dependent upon the Archimedes number of the jet. Increases in the buoyancy forces cause greater air velocities in the vicinity of the surgical site increasing the likelihood of deposition of contaminants in the flow field. The outcome of this study shows the Archimedes number should be used as the design parameter for hospital operating room air distribution in order to maintain a proper supply air jet for covering the sterile region. This work is supported by ASHRAE.

  6. $2^n-$rational maps

    OpenAIRE

    Kassotakis, Pavlos; Nieszporski, Maciej; Damianou, Pantelis

    2015-01-01

    We present a natural extension of the notion of nondegenerate rational maps (quadrirational maps) to arbitrary dimensions. We refer to these maps as $2^n-$rational maps. In this note we construct a rich family of $2^n-$rational maps. These maps by construction are involutions and highly symmetric in the sense that the maps and their companion maps have the same functional form.

  7. Monitoring proton radiation therapy with in-room PET imaging

    Science.gov (United States)

    Zhu, Xuping; España, Samuel; Daartz, Juliane; Liebsch, Norbert; Ouyang, Jinsong; Paganetti, Harald; Bortfeld, Thomas R.; El Fakhri, Georges

    2011-07-01

    We used a mobile positron emission tomography (PET) scanner positioned within the proton therapy treatment room to study the feasibility of proton range verification with an in-room, stand-alone PET system, and compared with off-line equivalent studies. Two subjects with adenoid cystic carcinoma were enrolled into a pilot study in which in-room PET scans were acquired in list-mode after a routine fractionated treatment session. The list-mode PET data were reconstructed with different time schemes to generate in-room short, in-room long and off-line equivalent (by skipping coincidences from the first 15 min during the list-mode reconstruction) PET images for comparison in activity distribution patterns. A phantom study was followed to evaluate the accuracy of range verification for different reconstruction time schemes quantitatively. The in-room PET has a higher sensitivity compared to the off-line modality so that the PET acquisition time can be greatly reduced from 30 to soft-tissue regions were better retained with in-room short PET acquisitions because of the collection of 15O component and lower biological washout. For soft tissue-equivalent material, the distal fall-off edge of an in-room short acquisition is deeper compared to an off-line equivalent scan, indicating a better coverage of the high-dose end of the beam. In-room PET is a promising low cost, high sensitivity modality for the in vivo verification of proton therapy. Better accuracy in Monte Carlo predictions, especially for biological decay modeling, is necessary.

  8. On palaeogeographic map

    Directory of Open Access Journals (Sweden)

    Zeng-Zhao Feng

    2016-01-01

    Full Text Available The palaeogeographic map is a graphic representation of physical geographical characteristics in geological history periods and human history periods. It is the most important result of palaeogeographic study. The author, as the Editor-in-Chief of Journal of Palaeogeography, Chinese Edition and English Edition, aimed at the problems of the articles submitted to and published in the Journal of Palaeogeography in recent years and the relevant papers and books of others, and integrated with his practice of palaeogeographic study and mapping, wrote this paper. The content mainly includes the data of palaeogeographic mapping, the problems of palaeogeographic mapping method, the “Single factor analysis and multifactor comprehensive mapping method —— Methodology of quantitative lithofacies palaeogeography”, i.e., the “4 steps mapping method”, the nomenclature of each palaeogeographic unit in palaeogeographic map, the explanation of each palaeogeographic unit in palaeogeographic map, the explanation of significance of palaeogeographic map and palaeogeographic article, the evaluative standards of palaeogeographic map and palaeogeographic article, and the self-evaluation. Criticisms and corrections are welcome.

  9. Principles of Electroanatomic Mapping

    Directory of Open Access Journals (Sweden)

    Deepak Bhakta

    2008-02-01

    Full Text Available Electrophysiologic testing and radiofrequency ablation have evolved as curative measures for a variety of rhythm disturbances. As experience in this field has grown, ablation is progressively being used to address more complex rhythm disturbances. Paralleling this trend are technological advancements to facilitate these efforts, including electroanatomic mapping (EAM. At present, several different EAM systems utilizing various technologies are available to facilitate mapping and ablation. Use of these systems has been shown to reduce fluoroscopic exposure and radiation dose, with less significant effects on procedural duration and success rates. Among the data provided by EAM are chamber reconstruction, tagging of important anatomic landmarks and ablation lesions, display of diagnostic and mapping catheters without using fluoroscopy, activation mapping, and voltage (or scar mapping. Several EAM systems have specialized features, such as enhanced ability to map non-sustained or hemodynamically unstable arrhythmias, ability to display diagnostic as well as mapping catheter positions, and wide compatibility with a variety of catheters. Each EAM system has its strengths and weaknesses, and the system chosen must depend upon what data is required for procedural success (activation mapping, substrate mapping, cardiac geometry, the anticipated arrhythmia, the compatibility of the system with adjunctive tools (i.e. diagnostic and ablation catheters, and the operator's familiarity with the selected system. While EAM can offer significant assistance during an EP procedure, their incorrect or inappropriate application can substantially hamper mapping efforts and procedural success, and should not replace careful interpretation of data and strict adherence to electrophysiologic principles.

  10. Air Distribution in a Furnished Room Ventilated by Mixing Ventilation

    DEFF Research Database (Denmark)

    Nielsen, June Richter; Nielsen, Peter V.; Svidt, Kjeld

    Using isothermal full-scale experiments and two-dimensional isothermal CFD simulations it is investigated how normal office furniture influences the air movements in a room with mixing ventilation. Three different set-ups are made in the experiments and different sizes and locations of the furnit......Using isothermal full-scale experiments and two-dimensional isothermal CFD simulations it is investigated how normal office furniture influences the air movements in a room with mixing ventilation. Three different set-ups are made in the experiments and different sizes and locations...... of the furniture volume are simulated. The simulations are made in three different lengths of the room....

  11. Calculation of Vertical Temperature Gradients in Heated Rooms

    DEFF Research Database (Denmark)

    Overby, H.; Steen-Thøde, Mogens

    This paper deals with a simple model which predicts the vertical temperature gradient in a heated room. The gradient is calculated from a dimensionless temperature profile which is determined by two room air temperatures only, the mean temperature in the occupied zone and the mean temperature...... in the zone above the occupied zone. A model to calculate the two air temperatures has been developed and implemented in Suncode- PC, a thermal analysis programme for residential and small commercial buildings. The dimensionless temperature profile based on measurements in a laboratory test room is presented...

  12. Airflow and Temperature Distribution in Rooms with Displacement Ventilation

    DEFF Research Database (Denmark)

    Jacobsen, T. V.

    This thesis deals with air flow and temperature distribution in a room ventilated by the displacement principle. The characteristic features of the ventilation system are treated in the whole room but main emphasis is laid on the analysis of the stratified flow region in front of the inlet device....... After a prefatory description of the background and the fundamentals of displacement ventilation the objectives of the current study are specified. The subsequent sections describe the measurements of velocity and temperature profiles carried out in a full scale test room. Based on experimental data...

  13. Evaluation of Sound Quality, Boominess and Boxiness in Small Rooms

    DEFF Research Database (Denmark)

    Weisser, Adam; Rindel, Jens Holger

    2006-01-01

    ratings. The classical bass ratio definitions showed poor correlation with all subjective ratings. The overall sound quality ratings gave different results for speech and music. For speech the preferred mean RT should be as low as possible, whereas for music there was found a preferred range between 0......The acoustics of small rooms has been studied with emphasis on sound quality, boominess and boxiness when the rooms are used for speech or music. Seven rooms with very different characteristics have been used for the study. Subjective listening tests were made using binaural recordings...

  14. Estimation of acoustic resonances for room transfer function equalization

    DEFF Research Database (Denmark)

    Gil-Cacho, Pepe; van Waterschoot, Toon; Moonen, Marc

    2010-01-01

    Strong acoustic resonances create long room impulse responses (RIRs) which may harm the speech transmission in an acoustic space and hence reduce speech intelligibility. Equalization is performed by cancelling the main acoustic resonances common to multiple room transfer functions (RTFs), i.......e., common-acoustical-poles, in the room. This paper discusses the utilization of different norms (i.e., 2-norm and 1-norm) and models (i.e., all-pole and pole-zero) for RTF modelling and then equalization. Acoustic resonances may be modelled by means of the poles of the RTF. In the literature, however...

  15. Eggcrate UV: a whole ceiling upper-room ultraviolet germicidal irradiation system for air disinfection in occupied rooms.

    Science.gov (United States)

    Linnes, J C; Rudnick, S N; Hunt, G M; McDevitt, J J; Nardell, E A

    2014-04-01

    A novel whole ceiling upper-room ultraviolet germicidal irradiation (UVGI) system [eggcrate ultraviolet (UV)] has been developed that incorporates open-cell 'eggcrate'-suspended ceiling panels and bare UV lamps with a ceiling fan. Upper-room UVGI is more effective for air disinfection than mechanical ventilation at much lower installation and operating costs. Conventional upper-room UVGI fixtures employ multiple tightly spaced horizontal louvers to confine UV to the upper-room. These louvered fixtures protect occupants in the lower-room from UV-induced eye and skin irritation, but at a major cost to fixture efficiency. Using a lamp and ballast from a conventional upper-room UVGI fixture in the eggcrate UV system, the germicidal efficacy was markedly improved even though the UV radiation emitted by the lamp was unchanged. This fundamental change in the application of upper-room UVGI air disinfection should permit wider, more effective application of UVGI globally to reduce the spread of airborne infection. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. The effect of dynamic solar shading on energy, daylighting and thermal comfort in a nearly zero-energy loft room in Rome and Copenhagen

    DEFF Research Database (Denmark)

    Skarning, Gunnlaug Cecilie Jensen; Hviid, Christian Anker; Svendsen, Svend

    2017-01-01

    alternatives in buildings with very low space-heating demand, this study mapped and compared energy, daylighting and thermal comfort for various combinations of window size and glazing properties, with and without dynamic shading. The study considered a loft room with sloped roof windows and moderate venting....... However, dynamic shading could not improve the optimum space-heating demand of the loft room in any predictable way, and without using dynamic shading, illuminances of 300 lx in 75% of the space could be achieved in 50–63% of the daylight hours with no more than 40–100 h exceeding the comfort ranges...

  17. Of maps and myths

    Energy Technology Data Exchange (ETDEWEB)

    Estes, J.E.; Mooneyhan, D.W. [Univ. Space Research Assoc, Washington, DC (United States)

    1994-05-01

    For many areas of both the developed and developing world, the spatially accurate data required to effectively support environmental planning, resources management, and public policy decision making do not exist. There are a variety of reasons for this lack of map data. Mapping is neither easy nor cheap. Issues of both national security and national sovereignty are involved. There is a need to reinvigorate and expand our mapping programs to make them national in focus but global in scope. It is also essential that a civil agency be given a load role in global mapping. There is a need to work to break down the barriers that inhibit the open flow of map information that does exist, garner the resources required to fill in where there are gaps, and support efforts to increase funding for research in mapping and spatial analysis. All this must be done if we are to improve our understanding of our rapidly changing world. 20 refs.

  18. Map Projection Transitions

    Directory of Open Access Journals (Sweden)

    Nedjeljko Frančula

    2013-06-01

    Full Text Available Map Projection Transitions is a very successful web application about map projections. The web page (http://www.jasondavies.com/maps/transition pre­sents a world map with graticule and country borders in the oblique Aitoff projection, with the South Pole. The map is not static, but animated. The South Pole moves toward the bottom and Earth rotates around its poles. The animation lasts five seconds, after which the projection changes and movement continues for five seconds, after which the projection changes again. Names of projections appear in a separate window. There are a total of 56 projections. The South Pole eventually becomes invisible and the North Pole appears at the top. Various parts of Earth appear in the center of the map by rotating around the poles.

  19. Advances in Reverberation Mapping

    OpenAIRE

    Kaspi, Shai

    2007-01-01

    This contribution briefly reviews the reverberation mapping technique which leads to determination of black hole masses. I focus on the emerging relation between the broad-line region size and the active galactic nucleus (AGN) luminosity, and on an overview of recent results of reverberation mapping studies which are starting to cover the full AGN luminosity range. Preliminary results and time lag determination from a reverberation mapping program of high-luminosity quasars are also presented.

  20. Classification of Lipschitz mappings

    CERN Document Server

    Piasecki, Lukasz

    2013-01-01

    The Lipschitz Condition Nonlinear spectral radius Uniformly lipschitzian mappings Basic Facts on Banach Spaces Convexity The operator norm Dual spaces, reexivity, the weak, and weak* topologiesMean Lipschitz Condition Nonexpansive and mean nonexpansive mappings in Banach spaces General case On the Lipschitz Constants for Iterates of Mean Lipschitzian Mappings A bound for Lipschitz constants of iterates A bound for the constant k∞(T)Moving averages in Bana

  1. Impact of changed management policies on operating room efficiency

    National Research Council Canada - National Science Library

    Sandbaek, Birgithe E; Helgheim, Berit I; Larsen, Odd I; Fasting, Sigurd

    2014-01-01

    To increase operating room (OR) efficiency, a new resource allocation strategy, a new policy for patient urgency classification, and a new system for OR booking was implemented at a tertiary referral hospital...

  2. Federal Reading Rooms for Risk Management Plans (RMP)

    Science.gov (United States)

    Reading Rooms, listed here by state, are open to the public by either appointment or walk-in. You may access Off-Site Consequence Analysis (scenarios) portions of RMPs, and take notes but not remove or reproduce materials.

  3. Simulating environmental and psychological acoustic factors of the operating room.

    Science.gov (United States)

    Bennett, Christopher L; Dudaryk, Roman; Ayers, Andrew L; McNeer, Richard R

    2015-12-01

    In this study, an operating room simulation environment was adapted to include quadraphonic speakers, which were used to recreate a composed clinical soundscape. To assess validity of the composed soundscape, several acoustic parameters of this simulated environment were acquired in the presence of alarms only, background noise only, or both. These parameters were also measured for comparison from size-matched operating rooms at Jackson Memorial Hospital. The parameters examined included sound level, reverberation time, and predictive metrics of speech intelligibility in quiet and noise. It was found that the sound levels and acoustic parameters were comparable between the simulated environment and the actual operating rooms. The impact of the background noise on the perception of medical alarms was then examined, and was found to have little impact on the audibility of the alarms. This study is a first in kind report of a comparison between the environmental and psychological acoustical parameters of a hospital simulation environment and actual operating rooms.

  4. Room temperature synthesis of biodiesel using sulfonated graphitic carbon nitride

    Science.gov (United States)

    Sulfonation of graphitic carbon nitride (g-CN) affords a polar and strongly acidic catalyst, Sg-CN, which displays unprecedented reactivity and selectivity in biodiesel synthesis and esterification reactions at room temperature.

  5. Enhanced room temperature multiferroicity in Gd doped BFO

    CSIR Research Space (South Africa)

    Pradhan, SK

    2009-01-01

    Full Text Available A signature of enhanced multiferroic behavior at room temperature has been observed in Gd doped Bismuth Ferrite system. This paper reports the preliminary findings/observations of structural and magnetization measurement of bismuth rich iron...

  6. 46 CFR 190.20-25 - Washrooms and toilet rooms.

    Science.gov (United States)

    2010-10-01

    ... and toilet rooms. (a) There must be provided at least 1 toilet, 1 washbasin, and 1 shower or bathtub..., showers, and bathtubs must be equipped with adequate plumbing, including hot and cold running water. All...

  7. Fabrication method for a room temperature hydrogen sensor

    Science.gov (United States)

    Seal, Sudipta (Inventor); Shukla, Satyajit V. (Inventor); Ludwig, Lawrence (Inventor); Cho, Hyoung (Inventor)

    2011-01-01

    A sensor for selectively determining the presence and measuring the amount of hydrogen in the vicinity of the sensor. The sensor comprises a MEMS device coated with a nanostructured thin film of indium oxide doped tin oxide with an over layer of nanostructured barium cerate with platinum catalyst nanoparticles. Initial exposure to a UV light source, at room temperature, causes burning of organic residues present on the sensor surface and provides a clean surface for sensing hydrogen at room temperature. A giant room temperature hydrogen sensitivity is observed after making the UV source off. The hydrogen sensor of the invention can be usefully employed for the detection of hydrogen in an environment susceptible to the incursion or generation of hydrogen and may be conveniently used at room temperature.

  8. Translanguaging as a class/lecture-room language management ...

    African Journals Online (AJOL)

    socio) linguistics, namely translanguaging and language management using auto-ethnographic snapshots from class/lecture-room contexts in Kenya and South Africa. Translanguaging entails recognition of a full account of speakers' discursive ...

  9. Game theory: applications for surgeons and the operating room environment.

    Science.gov (United States)

    McFadden, David W; Tsai, Mitchell; Kadry, Bassam; Souba, Wiley W

    2012-11-01

    Game theory is an economic system of strategic behavior, often referred to as the "theory of social situations." Very little has been written in the medical literature about game theory or its applications, yet the practice of surgery and the operating room environment clearly involves multiple social situations with both cooperative and non-cooperative behaviors. A comprehensive review was performed of the medical literature on game theory and its medical applications. Definitive resources on the subject were also examined and applied to surgery and the operating room whenever possible. Applications of game theory and its proposed dilemmas abound in the practicing surgeon's world, especially in the operating room environment. The surgeon with a basic understanding of game theory principles is better prepared for understanding and navigating the complex Operating Room system and optimizing cooperative behaviors for the benefit all stakeholders. Copyright © 2012 Mosby, Inc. All rights reserved.

  10. Personal Exposure to Contaminant Sources in Ventilated Rooms

    DEFF Research Database (Denmark)

    Brohus, Henrik

    Three different tools for personal exposure assessment are presented. They are all able to consider the local influence of persons in ventilated rooms where concentration gradients prevail: A Breathing Thermal Manikin, a Computer Simulated Person, and a Trained Sensory Panel. The tools are applied...... on the two major room ventilation principles. A personal exposure model for a displacement ventilated room is proposed. Two new quantities describing the interaction between a person and the ventilation are defined. The findings clearly stress the need for an improved exposure assessment in cases where...... a contaminant source is located in the vicinity of persons. It is also shown that it is not sufficient to know the local concentration level of an empty room, the local impact of a person is distinct and should be considered in the exposure assessment....

  11. A stable room-temperature sodium-sulfur battery

    National Research Council Canada - National Science Library

    Wei, Shuya; Xu, Shaomao; Agrawral, Akanksha; Choudhury, Snehashis; Lu, Yingying; Tu, Zhengyuan; Ma, Lin; Archer, Lynden A

    2016-01-01

    .... Rechargeable sodium-sulfur batteries able to operate stably at room temperature are among the most sought-after platforms because such cells take advantage of a two-electron-redox process to achieve...

  12. Influence of disturbances on bacteria level in an operating room

    DEFF Research Database (Denmark)

    Brohus, Henrik; Hyldig, Mikkel; Kamper, Simon

    2008-01-01

    In operating rooms great effort is manifested to reduce the bacteria level in order to decrease the risk of infections. The main source of bacteria is the staff and the patient, thus, the resulting bacteria concentration is roughly speaking a combination of the ventilation system and the emission...... from the occupants. This study investigates the influence of two main disturbances in an operating room namely the door opening during the operation and the activity level of the staff. It is found that the frequent door opening in this case does not cause significant transport of air from outside...... the operating room to the wound area of the patient. However, a significant influence of the activity level on the bacteria emission and concentration is found. Counting the number of persons in an operating room to estimate the bacteria source strength is not sufficient, the corresponding activity level must...

  13. High Power Room Temperature Terahertz Local Oscillator Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to build a high-power, room temperature compact continuous wave terahertz local oscillator for driving heterodyne receivers in the 1-5 THz frequency...

  14. Measures of Rehospitalization, Emergency Room Visit, and Community Discharge

    Data.gov (United States)

    U.S. Department of Health & Human Services — Measures of the Rate of Rehospitalization, Emergency Room Visit, and Community Discharge for Medicare Beneficiaries. These rates are based on Medicare claims data.

  15. Design of a multisystem remote maintenance control room

    Energy Technology Data Exchange (ETDEWEB)

    Draper, J.V.; Handel, S.J.; Kring, C.T.; Kawatsuma, S.

    1988-01-01

    The Remote Systems Development Section of the Consolidated Fuel Reprocessing Program at the Oak Ridge National Laboratory (ORNL) and Japan's Power Reactor and Nuclear Fuel Development Corporation (PNC) recently collaborated in the development of a control room concept for remote operations. This report describes design methods and the resulting control room concept. The design project included five stages. The first was compilation of a complete function list; functions are tasks performed by operators in the control room while operating equipment located in the remote area. The second step was organization of the function list into ''function groups;'' function groups are sets of functions that operate one piece of equipment. The third stage was determination of crew size and requirements for supervision. The fourth stage was development of conceptual designs of displays and controls. The fifth stage was development of plans for placement of crew stations within the control room. 5 figs., 1 tab.

  16. Criteria of choosing building structures for rooftop boiler rooms

    Directory of Open Access Journals (Sweden)

    Plotnikov Artyom

    2018-01-01

    Full Text Available The paper investigates parameters of noise and vibration distribution in the territory of residential area depending on the structural materials and power of independent heat supply systems. Rooftop boiler rooms are decentralized heat supply systems in buildings. Today, residential areas are strongly affected by noise and vibrations. Adverse effects are isolated by buildings materials, protective shields and floating floors. Rooftop boiler rooms located in Tyumen city were investigated within this research. Structures of rooftop boiler rooms were analyzed. Acoustic analysis results and the parameters of equivalent continuous sound level are presented. An option for improvement of rooftop boiler rooms structures is suggested. Comparison of capital investments in construction and installation activities is carried out. Conclusion on capital investments required for noise protection is made.

  17. Acoustical criteria for hospital patient rooms: Resolving competing requirements

    Science.gov (United States)

    Brooks, Bennett M.

    2003-10-01

    The acoustical criteria for patient rooms in hospitals, nursing homes, and rehabilitation facilities may be based on several needs. One important requirement is that noise levels in the room be conducive to restful sleep. Also, caregivers must have easy auditory and visual access to the patients, and be able to hear vital sign monitor alarms. This often means that patient rooms are located near central nurse stations and that patient room doors are left open. Further, the recently published federal privacy standards developed by the U.S. Department of Health and Human Services (HSS) under the Health Insurance Portability and Accountability Act (HIPAA) require that ``appropriate physical safeguards'' be put in place to protect the confidentiality of patient health information. The simultaneous and competing requirements for speech privacy, caregiver access, and good sleeping conditions present a serious acoustical challenge to health care facility designers. Specific facility design issues and potential solution strategies are presented.

  18. Psychological meaning of the living room: a multidimensional ...

    African Journals Online (AJOL)

    Administrator

    rated as a first-time homeowner in a newly built house, has ... judgements people make of the appearances of ..... Fashion. Relaxed. Beautiful. Positive. Personal. Welcoming. Impressive .... the impression of the living room is “inviting”, the style.

  19. Air Distribution in a Room with Ceiling-Mounted Diffusers

    DEFF Research Database (Denmark)

    Nielsen, Peter V.; Heby, Thomas; Moeller-Jensen, Bertil

    2006-01-01

    distribution generated by a radial diffuser is partly controlled by the momentum flow from the diffusers and partly from gravity forces where the thermal load and the temperature difference between room air and supply air deflect the radial wall jet down into the occupied zone. The ceiling diffuser......Experiments with air distribution in rooms generated by a radial ceiling-mounted diffuser and a diffuser generating flow with swirl are compared with the air distribution obtained by mixing ventilation from a wall-mounted diffuser, vertical ventilation and displacement ventilation. The air...... with swirling flow generates a flow pattern in the room which is rather uninfluenced by the thermal load. The flow is highly mixed above the occupied zone and the air movement penetrates the occupied zone close to the walls. All systems are tested in the same room with the same heat load consisting of two...

  20. Efficiency of hydrogen peroxide in improving disinfection of ICU rooms.

    Science.gov (United States)

    Blazejewski, Caroline; Wallet, Frédéric; Rouzé, Anahita; Le Guern, Rémi; Ponthieux, Sylvie; Salleron, Julia; Nseir, Saad

    2015-02-02

    The primary objective of this study was to determine the efficiency of hydrogen peroxide (H₂O₂) techniques in disinfection of ICU rooms contaminated with multidrug-resistant organisms (MDRO) after patient discharge. Secondary objectives included comparison of the efficiency of a vaporizator (HPV, Bioquell) and an aerosolizer using H₂O₂, and peracetic acid (aHPP, Anios) in MDRO environmental disinfection, and assessment of toxicity of these techniques. This prospective cross-over study was conducted in five medical and surgical ICUs located in one University hospital, during a 12-week period. Routine terminal cleaning was followed by H₂O₂ disinfection. A total of 24 environmental bacteriological samplings were collected per room, from eight frequently touched surfaces, at three time-points: after patient discharge (T0), after terminal cleaning (T1) and after H₂O₂ disinfection (T2). In total 182 rooms were studied, including 89 (49%) disinfected with aHPP and 93 (51%) with HPV. At T0, 15/182 (8%) rooms were contaminated with at least 1 MDRO (extended spectrum β-lactamase-producing Gram-negative bacilli 50%, imipenem resistant Acinetobacter baumannii 29%, methicillin-resistant Staphylococcus aureus 17%, and Pseudomonas aeruginosa resistant to ceftazidime or imipenem 4%). Routine terminal cleaning reduced environmental bacterial load (P efficiency on MDRO (15/182 (8%) rooms at T0 versus 11/182 (6%) at T1; P = 0.371). H₂O₂ technologies were efficient for environmental MDRO decontamination (6% of rooms contaminated with MDRO at T1 versus 0.5% at T2, P = 0.004). Patient characteristics were similar in aHPP and HPV groups. No significant difference was found between aHPP and HPV regarding the rate of rooms contaminated with MDRO at T2 (P = 0.313). 42% of room occupants were MDRO carriers. The highest rate of rooms contaminated with MDRO was found in rooms where patients stayed for a longer period of time, and where a patient with MDRO was