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Sample records for ps pulse duration

  1. Optimization of passively mode-locked Nd:GdVO4 laser with the selectable pulse duration 15-70 ps

    Science.gov (United States)

    Frank, Milan; Jelínek, Michal; Vyhlídal, David; Kubeček, Václav

    2016-12-01

    In this paper the optimization of a continuously diode-pumped Nd:GdVO4 laser oscillator in bounce geometry passively mode-locked using semiconductor saturable absorber mirror is presented. In the previous results the Nd:GdVO4 laser system generating 30 ps pulses with the average output power of 6.9 W at the repetition rate of 200 MHz at the wavelength of 1063 nm was reported. Now we are demonstrating up to three times increase of peak power due to the optimization of mode-matching in the laser resonator. Depending on the oscillator configuration we obtained the stable continuously mode-locked operation with pulses having selectable duration from 15 ps to 70 ps with the average output power of 7 W and the repetition rate of 150 MHz.

  2. Investigation of laser damage in single layer coatings with pulse durations from 45fs to 24ps

    Science.gov (United States)

    Mangote, B.; Gallais, L.; Melninkaitis, A.; Mirauskas, J.; Zerrad, M.; Jeskevic, M.; Sirutkaitis, V.; Commandré, M.

    2010-11-01

    Single shot LIDT of single layer coatings of different deposited materials (SiO2, HfO2, Ta2O5 and Nb2O5) have been studied. We report dependence of the damage threshold with different operational and material parameters (pulse duration, nature of the deposited material, deposition process or thickness of the layer). For interpretation a model dedicated to optical coatings and based on the conduction band electron rate equation is used. The simulations are compared to experiments. The theoretical approach is in good accordance to the experimental data.

  3. Compressed 6 ps pulse in nonlinear amplification of a Q-switched microchip laser

    Science.gov (United States)

    Diao, Ruxin; Liu, Zuosheng; Niu, Fuzeng; Wang, Aimin; Taira, Takunori; Zhang, Zhigang

    2017-02-01

    We present a passively Q-switched Nd:YVO4 crystal microchip laser with a 6 ps pulse width, which is based on SPM-induced spectral broadening and pulse compression. The passive Q-switching is obtained by a semiconductor saturable absorber mirror. The laser’s seed source centered at 1064 nm pulses with a duration of 80 ps, at a repetition rate of 600 kHz corresponding to an average output power of 10 mW. After amplification and compression, the pulses were compressed to 6 ps with a maximum pulse energy of 0.5 µJ.

  4. Comparison of soft and hard tissue ablation with sub-ps and ns pulse lasers

    Energy Technology Data Exchange (ETDEWEB)

    Da Silva, L.B.; Stuart, B.C.; Celliers, P.M.; Feit, M.D.; Glinsky, M.E.; Heredia, N.J.; Herman, S.; Lane, S.M.; London, R.A.; Matthews, D.L.; Perry, M.D.; Rubenchik, A.M. [Lawrence Livermore National Lab., CA (United States); Chang, T.D. [Veterans Administration Hospital, Martinez, CA (United States); Neev, J. [Beckman Laser Inst. and Medical Clinic, Irvine, CA (United States)

    1996-05-01

    Tissue ablation with ultrashort laser pulses offers several unique advantages. The nonlinear energy deposition is insensitive to tissue type, allowing this tool to be used for soft and hard tissue ablation. The localized energy deposition lead to precise ablation depth and minimal collateral damage. This paper reports on efforts to study and demonstrate tissue ablation using an ultrashort pulse laser. Ablation efficiency and extent of collateral damage for 0.3 ps and 1000 ps duration laser pulses are compared. Temperature measurements of the rear surface of a tooth section is also presented.

  5. Modeling of ablation threshold dependence on pulse duration for dielectrics with ultrashort pulsed laser

    Science.gov (United States)

    Sun, Mingying; Zhu, Jianqiang; Lin, Zunqi

    2017-01-01

    We present a numerical model of plasma formation in ultrafast laser ablation on the dielectrics surface. Ablation threshold dependence on pulse duration is predicted with the model and the numerical results for water agrees well with the experimental data for pulse duration from 140 fs to 10 ps. Influences of parameters and approximations of photo- and avalanche-ionization on the ablation threshold prediction are analyzed in detail for various pulse lengths. The calculated ablation threshold is strongly dependent on electron collision time for all the pulse durations. The complete photoionization model is preferred for pulses shorter than 1 ps rather than the multiphoton ionization approximations. The transition time of inverse bremsstrahlung absorption needs to be considered when pulses are shorter than 5 ps and it can also ensure the avalanche ionization (AI) coefficient consistent with that in multiple rate equations (MREs) for pulses shorter than 300 fs. The threshold electron density for AI is only crucial for longer pulses. It is reasonable to ignore the recombination loss for pulses shorter than 100 fs. In addition to thermal transport and hydrodynamics, neglecting the threshold density for AI and recombination could also contribute to the disagreements between the numerical and the experimental results for longer pulses.

  6. 1000-V, 300-ps pulse-generation circuit using silicon avalanche devices

    Science.gov (United States)

    Benzel, D. M.; Pocha, M. D.

    1985-07-01

    A Marx configured avalanche transistor string and a pulse rise-time peaking diode are used to generate pulses of >1000 V into a 50-Ω load with rise times of less than 300 ps. The trigger delay of this circuit is about 7-10 ns, with jitter <100 ps. This circuit has been used to generate pulses at a repetition rate up to 5 kHz.

  7. Optimum Pump Pulse Duration for X-Ray Ar-Plasma Lasing

    Directory of Open Access Journals (Sweden)

    Leili Masoudnia

    2015-02-01

    Full Text Available In plasma-driven X-ray lasers, it is critical to optimize the duration and time delay between pump pulses. In this study, we have done parametric simulations in order to systematically investigate the optimum time configuration of pump pulses. Here, we are mainly interested in soft X-ray lasers created using a Ar target irradiated with laser pulses, which operate at a wavelength \\(\\lambda=46.9\\ nm in the \\(2p^5 3p^1(J=0\\rightarrow 2p^5 3s^1(J=1\\ laser transition. It is shown that the optimum time scale required to achieve Ne-like ions, as well as the time required to generate a population inversion depend on the combined effect of the electron temperature and electron density. The electron density and temperature are respectively a factor of \\(\\approx\\\\(2.1\\- and \\(\\approx\\\\(5\\-times higher in the case of a short pulse of \\(0.1\\ ps in comparison to a long pulse of 1,000 ps (at a constant fluence. The most effective lasing happens with short pulses with a pulse duration comparable to the total relaxation time from the upper level, namely \\(\\Delta\\tau_p\\leq35\\ ps. Power laws to predict the optimum laser intensity to achieve Ne-like \\(Ar^{+8}\\ are obtained.

  8. CW seeded optical parametric amplifier providing wavelength and pulse duration tunable nearly transform limited pulses.

    Science.gov (United States)

    Hädrich, S; Gottschall, T; Rothhardt, J; Limpert, J; Tünnermann, A

    2010-02-01

    An optical parametric amplifier that delivers nearly transform limited pulses is presented. The center wavelength of these pulses can be tuned between 993 nm and 1070 nm and, at the same time, the pulse duration is varied between 206 fs and 650 fs. At the shortest pulse duration the pulse energy was increased up to 7.2 microJ at 50 kHz repetition rate. Variation of the wavelength is achieved by applying a tunable cw seed while the pulse duration can be varied via altering the pump pulse duration. This scheme offers superior flexibility and scaling possibilities.

  9. Pulse duration and wavelength stability measurements of a midinfrared free-electron laser.

    Science.gov (United States)

    Qin, Yu; Zen, Heishun; Wang, Xiaolong; Kii, Toshiteru; Nakajima, Takashi; Ohgaki, Hideaki

    2013-04-01

    We report the pulse duration and wavelength stability measurements of a midinfrared free-electron laser (FEL) where the wavelength fluctuation may not be negligible. The technique we employ is a fringe-resolved autocorrelation (FRAC) method that has good sensitivity on not only the pulse duration and the chirp but also the wavelength stability. By the simple manipulation of experimental FRAC signals, we can obtain the pulse duration even if the amounts of the chirp and the wavelength stability are not known in advance, which is further used to estimate the wavelength stability. Through this procedure we find that the pulse duration of the Kyoto University FEL at 12 μm is about 0.58 ps without any notable chirp, and the wavelength stability is about 1.3%. We also carry out separate experiments for intensity autocorrelation and sum-frequency mixing. The difference we find for pulse duration and wavelength stability by the different measurements is attributed to the different operation conditions of FEL.

  10. Dynamic Characterization of Fiber Optical Chirped Pulse Amplification for Sub-ps Pulses

    DEFF Research Database (Denmark)

    Cristofori, Valentina; Lali-Dastjerdi, Zohreh; Rishøj, Lars Søgaard

    2013-01-01

    We investigate experimentally the propagation of sub-picosecond pulses in fiber optical parametric chirped pulse amplifiers, showing a significant broadening of the pulses from 450 fs up to 720 fs due to dispersion and self-phase modulation.......We investigate experimentally the propagation of sub-picosecond pulses in fiber optical parametric chirped pulse amplifiers, showing a significant broadening of the pulses from 450 fs up to 720 fs due to dispersion and self-phase modulation....

  11. Pulse Duration of Seeded Free-Electron Lasers

    Science.gov (United States)

    Finetti, Paola; Höppner, Hauke; Allaria, Enrico; Callegari, Carlo; Capotondi, Flavio; Cinquegrana, Paolo; Coreno, Marcello; Cucini, Riccardo; Danailov, Miltcho B.; Demidovich, Alexander; De Ninno, Giovanni; Di Fraia, Michele; Feifel, Raimund; Ferrari, Eugenio; Fröhlich, Lars; Gauthier, David; Golz, Torsten; Grazioli, Cesare; Kai, Yun; Kurdi, Gabor; Mahne, Nicola; Manfredda, Michele; Medvedev, Nikita; Nikolov, Ivaylo P.; Pedersoli, Emanuele; Penco, Giuseppe; Plekan, Oksana; Prandolini, Mark J.; Prince, Kevin C.; Raimondi, Lorenzo; Rebernik, Primoz; Riedel, Robert; Roussel, Eleonore; Sigalotti, Paolo; Squibb, Richard; Stojanovic, Nikola; Stranges, Stefano; Svetina, Cristian; Tanikawa, Takanori; Teubner, Ulrich; Tkachenko, Victor; Toleikis, Sven; Zangrando, Marco; Ziaja, Beata; Tavella, Franz; Giannessi, Luca

    2017-04-01

    The pulse duration, and, more generally, the temporal intensity profile of free-electron laser (FEL) pulses, is of utmost importance for exploring the new perspectives offered by FELs; it is a nontrivial experimental parameter that needs to be characterized. We measured the pulse shape of an extreme ultraviolet externally seeded FEL operating in high-gain harmonic generation mode. Two different methods based on the cross-correlation of the FEL pulses with an external optical laser were used. The two methods, one capable of single-shot performance, may both be implemented as online diagnostics in FEL facilities. The measurements were carried out at the seeded FEL facility FERMI. The FEL temporal pulse characteristics were measured and studied in a range of FEL wavelengths and machine settings, and they were compared to the predictions of a theoretical model. The measurements allowed a direct observation of the pulse lengthening and splitting at saturation, in agreement with the proposed theory.

  12. TDR Using Autocorrelation and Varying-Duration Pulses

    Science.gov (United States)

    Lucena, Angel; Mullinex, Pam; Huang, PoTien; Santiago, Josephine; Mata, Carlos; Zavala, Carlos; Lane, John

    2008-01-01

    In an alternative to a prior technique of time-domain-reflectometry (TDR) in which very short excitation pulses are used, the pulses have very short rise and fall times and the pulse duration is varied continuously between a minimum and a maximum value. In both the present and prior techniques, the basic idea is to (1) measure the times between the generation of excitation pulses and the reception of reflections of the pulses as indications of the locations of one or more defects along a cable and (2) measure the amplitudes of the reflections as indication of the magnitudes of the defects. In general, an excitation pulse has a duration T. Each leading and trailing edge of an excitation pulse generates a reflection from a defect, so that a unique pair of reflections is associated with each defect. In the present alternative technique, the processing of the measured reflection signal includes computation of the autocorrelation function R(tau) identical with fx(t)x(t-tau)dt where t is time, x(t) is the measured reflection signal at time t, and taus is the correlation interval. The integration is performed over a measurement time interval short enough to enable identification and location of a defect within the corresponding spatial interval along the cable. Typically, where there is a defect, R(tau) exhibits a negative peak having maximum magnitude for tau in the vicinity of T. This peak can be used as a means of identifying a leading-edge/trailing-edge reflection pair. For a given spatial interval, measurements are made and R(tau) computed, as described above, for pulse durations T ranging from the minimum to the maximum value. The advantage of doing this is that the effective signal-to-noise ratio may be significantly increased over that attainable by use of a fixed pulse duration T.

  13. Determination of optimum proton pulse duration for triggering fast ignition in inertial confinement fusion

    Directory of Open Access Journals (Sweden)

    A. Ghasemizad

    2007-03-01

    Full Text Available  Two relatively simple analytic Models for investigation of fast ignition dynamics are developed, that are the subsonic and the supersonic models. On the basis of the subsonic model, which a pre-compressed fuel of density is heated by a subsonic thermal wave, the beam energy and the intensity required for ignition is closely related to proton range. Whereas, on the basis of supersonic model, for ranges shorter than 0.25 gr/cm2 , the mentioned energy remains constant and the intensity decreases. For ranges larger than this value, not only energy but also the beam intensity will increase with the proton range. Considering that proton pulse duration depend on proton range implicitly, these results allow for the determination of an optimum proton pulse duration value, that we have obtained this value equal to 2.14×103 po-1  ps.

  14. Carbon dioxide laser with a variable output pulse duration

    Energy Technology Data Exchange (ETDEWEB)

    Apollonov, V.V.; Akhunov, N.; Derzhavin, S.I.; Kononov, I.K.; Sirotkin, A.A.; Firsov, K.N.; Yamshchikov, V.A.

    1983-09-01

    A report is given of the construction of a CO/sub 2/ laser in which the exciting discharge was stabilized by adding readily ionized organic substances to the mixture. The temporal characteristics of the laser emission pulses were investigated for a wide range of active mixtures and pulse durations from 10 ..mu..sec to 150 nsec. A discussion is given of improvements in the output energy distribution over the beam cross section.

  15. Generation of high current, long duration rectangular pulses

    CERN Document Server

    Faugeras, Paul E; Zanasco, J P

    1973-01-01

    The excitation of the fast pulsed kicker magnets foreseen for the CERN 400 GeV proton synchrotron requires rectangular pulses with a current amplitude of 3000 A to 10000 A, a pulse duration adjustable between 1 and 24 mu sec, and short rise and fall times. These pulses are generated by a LC ladder network discharged with fast switches. Several kinds of switches have been tested: multigap thyratrons of standard design, a composite switch called 'thyragnitron' and made of a normal thyratron by-passed ignitrons, and finally special thyratrons with a second cathode assembly in place of the usual anode. Experimental pulse shapes and results of life tests for these different switches are presented and discussed. (8 refs).

  16. Synthesis of ZnO thin films by 40 ps rate at 532 nm laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Ristoscu, C.; Socol, G.; Mihailescu, I.N. [National Institute for Lasers, Plasma and Radiations Physics, Lasers Department, 409 Atomistilor, P.O. Box MG-54, Magurele, Ilfov (Romania); Socol, M. [National Institute for Materials Physics, P.O. Box MG-7, Magurele, Ilfov (Romania); Jafer, R.; Al-Hadeethi, Y.; Batani, D. [Universita degli Studi di Milano-Bicocca, Dipartimento di Fisica ' ' G. Occhialini' ' , Milano (Italy)

    2011-09-15

    The synthesis by pulsed laser deposition of ZnO thin films with a Nd:YAG laser system delivering pulses of 40 ps rate at 532 nm is reported. The laser beam irradiated the target placed inside a vacuum chamber evacuated down to 1.33 x 10{sup -1} Pa. The incident laser fluence was of 28 J/cm{sup 2} in a spot of 0.1 mm{sup 2}. The ablated material was collected onto double face polished (111) Si or quartz wafers placed parallel at a separation distance of 7 mm. The AFM, SEM, UV-Vis, FT-IR and absorption ellipsometry results indicated that we obtained pure ZnO films with a rather uniform surface, having an average roughness of 37 nm. We observed by SEM that particulates are present on ZnO film surface or embedded into bulk. Their density and dimension were intermediary between particulates observed on similar structures deposited with fs or ns laser pulses. We noticed that the density of the particulates is increasing while their average size is decreasing when passing from ns to ps and fs laser pulses. The average transmission in the UV-Vis spectral region was found to be higher than 85%. (orig.)

  17. Investigation on repetition rate and pulse duration influences on ablation efficiency of metals using a high average power Yb-doped ultrafast laser

    Directory of Open Access Journals (Sweden)

    Lopez J.

    2013-11-01

    Full Text Available Ultrafast lasers provide an outstanding processing quality but their main drawback is the low removal rate per pulse compared to longer pulses. This limitation could be overcome by increasing both average power and repetition rate. In this paper, we report on the influence of high repetition rate and pulse duration on both ablation efficiency and processing quality on metals. All trials have been performed with a single tunable ultrafast laser (350 fs to 10ps.

  18. Optimal repetition rate and pulse duration studies for two photon imaging

    Science.gov (United States)

    Mirkhanov, Shamil; Quarterman, Adrian H.; Smyth, Connor J. C. P.; Praveen, Bavishna B.; Appleton, Paul; Thomson, Calum; Swift, Samuel; Wilcox, Keith G.

    2017-02-01

    Multiphoton imaging (MPI) is an important fluorescence microscopy technique that allows deep tissue and in-vivo imaging with high selectivity. According to theory, two-photon signal is proportional to the product of the peak power and the average power, allowing optimization of key imaging parameters of the excitation laser, such as average power, repetition rate and pulse duration. Recent progress in compact ultrafast lasers including femtosecond fiber lasers and optically pumped semiconductor lasers makes direct control of these parameters possible. In order to investigate the optimum laser parameters for two photon imaging we experimentally study the effects of repetition rate between 2.85 and 90 MHz and pulse duration between 336 fs and 3.5 ps on two photon signal in SYTOX Green labeled mouse intestine sections at 1030 nm. We found that the optimum repetition rate for this sample is in the range 20 - 40 MHz, depending on average power, and that the pulse duration has no effect on the MPI signal provided that the average power can be adjusted to keep the product of average and peak power constant.

  19. Laser system generating 250-mJ bunches of 5-GHz repetition rate, 12-ps pulses.

    Science.gov (United States)

    Agnesi, Antonio; Braggio, Caterina; Carrà, Luca; Pirzio, Federico; Lodo, Stefano; Messineo, Giuseppe; Scarpa, Daniele; Tomaselli, Alessandra; Reali, Giancarlo; Vacchi, Carla

    2008-09-29

    We report on a high-energy solid-state laser based on a master-oscillator power-amplifier system seeded by a 5-GHz repetition-rate mode-locked oscillator, aimed at the excitation of the dynamic Casimir effect by optically modulating a microwave resonator. Solid-state amplifiers provide up to 250 mJ at 1064 nm in a 500-ns (macro-)pulse envelope containing 12-ps (micro-)pulses, with a macro/micropulse format and energy resembling that of near-infrared free-electron lasers. Efficient second-harmonic conversion allowed synchronous pumping of an optical parametric oscillator, obtaining up to 40 mJ in the range 750-850 nm.

  20. Route to the minimum pulse duration in normal-dispersion fiber lasers

    Science.gov (United States)

    Chong, Andy; Renninger, William H.; Wise, Frank W.

    2011-01-01

    The factors that control the pulse duration in all-normal-dispersion lasers are identified. To minimize the pulse duration, the cavity dispersion should be as small as possible. For fixed dispersion, increasing pulse energy leads to shorter, but more-structured, pulses. Experiments performed with ordinary single-mode fiber at 1 μm wavelength agree reasonably with numerical simulations, and produce clean ~80-fs pulses. The simulations indicate that 30-fs pulses can be reached at higher energies. PMID:19015693

  1. Efficient energy absorption of intense ps-laser pulse into nanowire target

    Energy Technology Data Exchange (ETDEWEB)

    Habara, H.; Honda, S.; Katayama, M.; Tanaka, K. A. [Graduate School of Engineering, Osaka University, 2-1 Suita, Osaka 565-0871 (Japan); Sakagami, H. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Nagai, K. [Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Nagatsuda 4259, Midori-ku, Yokohama 226-8503, Kanagawa (Japan)

    2016-06-15

    The interaction between ultra-intense laser light and vertically aligned carbon nanotubes is investigated to demonstrate efficient laser-energy absorption in the ps laser-pulse regime. Results indicate a clear enhancement of the energy conversion from laser to energetic electrons and a simultaneously small plasma expansion on the surface of the target. A two-dimensional plasma particle calculation exhibits a high absorption through laser propagation deep into the nanotube array, even for a dense array whose structure is much smaller than the laser wavelength. The propagation leads to the radial expansion of plasma perpendicular to the nanotubes rather than to the front side. These features may contribute to fast ignition in inertial confinement fusion and laser particle acceleration, both of which require high current and small surface plasma simultaneously.

  2. Fetal pulse oximetry: duration of desaturation and intrapartum outcome.

    Science.gov (United States)

    Bloom, S L; Swindle, R G; McIntire, D D; Leveno, K J

    1999-06-01

    To analyze labor outcomes in relation to masked fetal arterial oxyhemoglobin saturation values above or below 30%. Consenting gravidas with uncomplicated pregnancies at or beyond 36 weeks' gestation underwent continuous fetal pulse oximetry. Pregnancy outcomes were compared between two groups: women with fetuses with at least one epoch of arterial oxyhemoglobin saturation below 30% (10 seconds or longer) and women with fetuses without such an episode. We also attempted to ascertain whether duration of saturation below 30% correlated with fetal compromise. We measured arterial oxyhemoglobin saturation in 129 fetuses, 69 (53%) of whom had at least one epoch of saturation below 30%. There were no statistically significant differences in labor and delivery outcomes between the high-saturation and low-saturation groups (eg, cesarean delivery: 13 versus 9%, P = .41; umbilical artery [UA] pH less than 7.20: 10 versus 9%, P > .999). However, as duration of fetal arterial oxyhemoglobin saturation below 30% increased from 10 seconds to longer than 9 consecutive minutes, the incidence of fetal compromise (considered present when at least one of the following criteria was met: cesarean delivery for nonreassuring fetal heart rate pattern, UA pH less than 7.20, admission to the special care nursery, or 5-minute Apgar score not more than 3) increased significantly (P = .002). The threshold duration of fetal arterial oxyhemoglobin saturation below 30% associated with increased fetal compromise was 2 minutes. Transient fetal arterial oxyhemoglobin saturation values below 30% are common during normal labor and did not predict fetal compromise. Fetal arterial oxyhemoglobin saturation values less than 30% for 2 minutes or longer might be associated with fetal compromise.

  3. Studies on perovskite film ablation and scribing with ns-, ps- and fs-laser pulses

    Science.gov (United States)

    Bayer, Lukas; Ye, Xinyuan; Lorenz, Pierre; Zimmer, Klaus

    2017-10-01

    Hybrid organic-inorganic perovskites attract much attention due to their exceptional optoelectronic properties, in particular for photovoltaic (PV) applications. The accurate, high-speed and reliable patterning of the PV films is required for perovskite solar modules fabrication. Laser scribing provides these characteristics needed for industrial fabrication processes. In this work, the laser ablation and scribing of perovskite layers (CH3NH3PbI3: MAPbI3) with different laser sources (ns-, ps-, fs-laser pulses with wavelengths of 248 nm to 2.5 µm) were systematically investigated. The perovskite material was irradiated from both the film side and the substrate (rear side) side to study and compare the particular processes. The patterning results of the perovskite film can be classified into (1) regular laser ablation, (2) thin-film delamination lift-off process, and (3) lift-off with thermal modifications. A particular process, the localised lift-off of single grains from the perovskite film, has been observed and is discussed in relation to the thin-film lift-off process. Ablation and ablation-related mechanisms provide good conditions for laser scribing of the perovskite layer required for module interconnection via P2.

  4. Pulse duration and wavelength stability measurements of a midinfrared free-electron laser

    OpenAIRE

    Qin, Yu; Zen, Heishun; Wang, Xiaolong; Kii, Toshiteru; Nakajima, Takashi; Ohgaki, Hideaki

    2013-01-01

    We report the pulse duration and wavelength stability measurements of a midinfrared free-electron laser (FEL) where the wavelength fluctuation may not be negligible. The technique we employ is a fringe-resolved autocorrelation (FRAC) method that has good sensitivity on not only the pulse duration and the chirp but also the wavelength stability. By the simple manipulation of experimental FRAC signals, we can obtain the pulse duration even if the amounts of the chirp and the wavelength stabilit...

  5. Superhigh-frequency radiometer with post-detector pulse-duration modulation

    CERN Document Server

    Filatov, A V

    2002-01-01

    Paper describes a superhigh-frequency radiometer with extra pulse-duration modulation of reference signal by low frequency. Pulse-duration modulation is realized due to various coefficients of reference signal sharing in resistive attenuators of a low-frequency unit. Design of radiometer makes use of modification of zero measurement method when automatic control is realized by variation of pulse-duration signal duration. Radiometer switching to zero balance in a low-frequency section enables to use high-frequency units of any modulating radiometer with symmetry modulation

  6. Copper bromide vapour laser with an output pulse duration of up to 320 ns

    Energy Technology Data Exchange (ETDEWEB)

    Gubarev, F A; Fedorov, K V; Evtushenko, G S [National Research Tomsk Polytechnic University, Tomsk (Russian Federation); Fedorov, V F; Shiyanov, D V [V.E. Zuev Institute of Atmospheric Optics, Siberian Branch, Russian Academy of Sciences, Tomsk (Russian Federation)

    2016-01-31

    We report the development of a copper bromide vapour laser with an output pulse duration of up to 320 ns. To lengthen the pulse, the discharge current was limited using a compound switch comprising a pulsed hydrogen thyratron and a tacitron. This technique permits limiting the excitation of the working levels at the initial stage of the discharge development to lengthen the inversion lifetime. The longest duration of a laser pulse was reached in tubes 25 and 50 mm in diameter for a pulse repetition rate of 2 – 4 kHz. (lasers and laser beams)

  7. Influence of laser pulse duration on extreme ultraviolet and ion emission features from tin plasmas

    Science.gov (United States)

    Roy, A.; Harilal, S. S.; Polek, M. P.; Hassan, S. M.; Endo, A.; Hassanein, A.

    2014-03-01

    We investigated the role of laser pulse duration and intensity on extreme ultraviolet (EUV) generation and ion emission from a laser produced Sn plasma. For producing plasmas, planar slabs of pure Sn were irradiated with 1064 nm Nd:YAG laser pulses with varying pulse duration (5-20 ns) and intensity. Experimental results performed at CMUXE indicate that the conversion efficiency (CE) of the EUV radiation strongly depend on laser pulse width and intensity, with a maximum CE of ˜2.0% measured for the shortest laser pulse width used (5 ns). Faraday Cup ion analysis of Sn plasma showed that the ion flux kinetic profiles are shifted to higher energy side with the reduction in laser pulse duration and narrower ion kinetic profiles are obtained for the longest pulse width used. However, our initial results showed that at a constant laser energy, the ion flux is more or less constant regardless of the excitation laser pulse width. The enhanced EUV emission obtained at shortest laser pulse duration studied is related to efficient laser-plasma reheating supported by presence of higher energy ions at these pulse durations.

  8. Influence of laser pulse duration on extreme ultraviolet and ion emission features from tin plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Roy, A., E-mail: roy@fzu.cz, E-mail: aroy@barc.gov.in [HiLASE Project, Department of Diode-Pumped Lasers, Institute of Physics of the ASCR, Na Slovance 2, 18221 Prague (Czech Republic); School of Nuclear Engineering and Center for Materials Under Extreme Environment (CMUXE), Purdue University, West Lafayette, Indiana 47907 (United States); Harilal, S. S.; Polek, M. P.; Hassan, S. M.; Hassanein, A. [School of Nuclear Engineering and Center for Materials Under Extreme Environment (CMUXE), Purdue University, West Lafayette, Indiana 47907 (United States); Endo, A. [HiLASE Project, Department of Diode-Pumped Lasers, Institute of Physics of the ASCR, Na Slovance 2, 18221 Prague (Czech Republic)

    2014-03-15

    We investigated the role of laser pulse duration and intensity on extreme ultraviolet (EUV) generation and ion emission from a laser produced Sn plasma. For producing plasmas, planar slabs of pure Sn were irradiated with 1064 nm Nd:YAG laser pulses with varying pulse duration (5–20 ns) and intensity. Experimental results performed at CMUXE indicate that the conversion efficiency (CE) of the EUV radiation strongly depend on laser pulse width and intensity, with a maximum CE of ∼2.0% measured for the shortest laser pulse width used (5 ns). Faraday Cup ion analysis of Sn plasma showed that the ion flux kinetic profiles are shifted to higher energy side with the reduction in laser pulse duration and narrower ion kinetic profiles are obtained for the longest pulse width used. However, our initial results showed that at a constant laser energy, the ion flux is more or less constant regardless of the excitation laser pulse width. The enhanced EUV emission obtained at shortest laser pulse duration studied is related to efficient laser-plasma reheating supported by presence of higher energy ions at these pulse durations.

  9. Impact of pulse duration on Ho:YAG laser lithotripsy: fragmentation and dusting performance.

    Science.gov (United States)

    Bader, Markus J; Pongratz, Thomas; Khoder, Wael; Stief, Christian G; Herrmann, Thomas; Nagele, Udo; Sroka, Ronald

    2015-04-01

    In vitro investigations of Ho:YAG laser-induced stone fragmentation were performed to identify potential impacts of different pulse durations on stone fragmentation characteristics. A Ho:YAG laser system (Swiss LaserClast, EMS S.A., Nyon, Switzerland) with selectable long or short pulse mode was tested with regard to its fragmentation and laser hardware compatibility properties. The pulse duration is depending on the specific laser parameters. Fragmentation tests (hand-held, hands-free, single-pulse-induced crater) on artificial BEGO stones were performed under reproducible experimental conditions (fibre sizes: 365 and 200 µm; laser settings: 10 W through combinations of 0.5, 1, 2 J/pulse and 20, 10, 5 Hz, respectively). Differences in fragmentation rates between the two pulse duration regimes were detected with statistical significance for defined settings. Hand-held and motivated Ho:YAG laser-assisted fragmentation of BEGO stones showed no significant difference between short pulse mode and long pulse mode, neither in fragmentation rates nor in number of fragments and fragment sizes. Similarly, the results of the hands-free fragmentation tests (with and without anti-repulsion device) showed no statistical differences between long pulse and short pulse modes. The study showed that fragmentation rates for long and short pulse durations at identical power settings remain at a comparable level. Longer holmium laser pulse duration reduces stone pushback. Therefore, longer laser pulses may result in better clinical outcome of laser lithotripsy and more convenient handling during clinical use without compromising fragmentation effectiveness.

  10. The impact of pulse duration on multiphoton ionization in the soft X-ray regime

    Science.gov (United States)

    Richter, Mathias; Sorokin, Andrey A.; Tiedtke, Kai

    2013-05-01

    At the soft X-ray free electron laser FLASH, multiphoton ionization of free atoms has been studied by ion time-of-flight spectroscopy. Depending on the multiphoton mechanism, the ionization processes are influenced in different ways by the FEL pulse duration. This feature has been used, e.g., to measure the pulse duration of FLASH in the femtosecond regime by non-linear autocorrelation. In the present contribution, the impact of pulse duration on multiphoton ionization is discussed with an emphasis on the distinction between sequential and non-sequential processes, and collective electron excitation as well.

  11. Sub-100 ps laser-driven dynamic compression of solid deuterium with a ˜40 μJ laser pulse

    Science.gov (United States)

    Armstrong, Michael R.; Crowhurst, Jonathan C.; Bastea, Sorin; Zaug, Joseph M.; Goncharov, Alexander F.

    2014-07-01

    We dynamically compress solid deuterium over <100 ps from initial pressures of 22 GPa to 55 GPa, to final pressures as high as 71 GPa, with <40 μJ of pulse energy. At 25 GPa initial pressure, we measure compression wave speeds consistent with quasi-isentropic compression and a 24% increase in density. The laser drive energy per unit density change is 109 times smaller than it is for recent longer (˜30 ns) time scale compression experiments. This suggests that, for a given final density, dynamic compression of hydrogen might be achieved using orders of magnitude lower laser energy than currently used.

  12. 197 nm femtosecond laser-pulse duration: comparison of autocorrelation measurements

    Science.gov (United States)

    Heisel, P.-C.; Bergmann, J.; Paa, W.; Triebel, W.; Zeuner, T.; Stafast, H.

    2013-08-01

    An easy and reliable way is presented to measure the duration of UV femtosecond laser pulses of λ autocorrelation techniques are based on two-photon absorption (TPA) in different TPA media, especially calcium fluoride (CaF2). For 197 nm, the laser-pulse energy transmission and the laser-induced fluorescence of self-trapped excitons at 278 nm are applied. Both methods yield nearly the same second-order autocorrelation functions allowing to analyze the investigated laser pulse and obtain its duration of fs.

  13. Effects of Beam Size and Pulse Duration on the Laser Drilling Process

    CERN Document Server

    Afrin, Nazia; Chen, J K; Zhang, Yuwen

    2016-01-01

    A two-dimensional axisymmetric transient laser drilling model is used to analyze the effects of laser beam diameter and laser pulse duration on the laser drilling process. The model includes conduction and convection heat transfer, melting, solidification and vaporization, as well as material removal resulting from the vaporization and melt ejection. The validated model is applied to study the effects of laser beam size and pulse duration on the geometry of the drilled hole. It is found that the ablation effect decrease with the increasing beam diameter due to the effect of increased vaporization rate, and deeper hole is observed for the larger pulse width due to the higher thermal ablation efficiency.

  14. Quasi-real-time photon pulse duration measurement by analysis of FEL radiation spectra

    Energy Technology Data Exchange (ETDEWEB)

    Engel, Robin, E-mail: robin.engel@uni-oldenburg.de [Deutsches Elektronen-Synchrotron, Notkestrasse 85, D-22603 Hamburg (Germany); Institut für Physik, Carl von Ossietzky Universität Oldenburg, D-26111 Oldenburg (Germany); Institut für Laser und Optik, Hochschule Emden/Leer, University of Applied Sciences, Constantiaplatz 4, D-26723 Emden (Germany); Düsterer, Stefan; Brenner, Günter [Deutsches Elektronen-Synchrotron, Notkestrasse 85, D-22603 Hamburg (Germany); Teubner, Ulrich [Deutsches Elektronen-Synchrotron, Notkestrasse 85, D-22603 Hamburg (Germany); Institut für Physik, Carl von Ossietzky Universität Oldenburg, D-26111 Oldenburg (Germany); Institut für Laser und Optik, Hochschule Emden/Leer, University of Applied Sciences, Constantiaplatz 4, D-26723 Emden (Germany)

    2016-01-01

    Considering the second-order spectral correlation function of SASE-FEL radiation allows a real-time observation of the photon pulse duration during spectra acquisition. For photon diagnostics at free-electron lasers (FELs), the determination of the photon pulse duration is an important challenge and a complex task. This is especially true for SASE FELs with strongly fluctuating pulse parameters. However, most techniques require an extensive experimental setup, data acquisition and evaluation time, limiting the usability in all-day operation. In contrast, the presented work uses an existing approach based on the analysis of statistical properties of measured SASE FEL spectra and implements it as a software tool, integrated in FLASH’s data acquisition system. This allows the calculation of the average pulse durations from a set of measured spectral distributions with only seconds of delay, whenever high-resolution spectra are recorded.

  15. Laser cutting of bone tissue under bulk water with a pulsed ps-laser at 532 nm

    Science.gov (United States)

    Tulea, Cristian-Alexander; Caron, Jan; Gehlich, Nils; Lenenbach, Achim; Noll, Reinhard; Loosen, Peter

    2015-10-01

    Hard-tissue ablation was already investigated for a broad variety of pulsed laser systems, which cover almost the entire range of available wavelengths and pulse parameters. Most effective in hard-tissue ablation are Er:YAG and CO2 lasers, both utilizing the effect of absorption of infrared wavelengths by water and so-called explosive vaporization, when a thin water film or water-air spray is supplied. The typical flow rates and the water layer thicknesses are too low for surgical applications where bleeding occurs and wound flushing is necessary. We studied a 20 W ps-laser with 532 nm wavelength and a pulse energy of 1 mJ to effectively ablate bones that are submerged 14 mm under water. For these laser parameters, the plasma-mediated ablation mechanism is dominant. Simulations based on the blow-off model predict the cut depth and cross-sectional shape of the incision. The model is modified considering the cross section of the Gaussian beam, the incident angle, and reflections. The ablation rate amounts to 0.2 mm3/s, corresponding to an increase by at least 50% of the highest values published so far for ultrashort laser ablation of hard tissue.

  16. Selective ablation of pit and fissure caries from occlusal surfaces using λ=355-nm laser pulses and air-abrasion demonstrated using PS-OCT and near-IR imaging

    Science.gov (United States)

    Ross, Steven T.; Fan, Kenneth; Fried, Daniel

    2006-02-01

    Several past studies have suggested that lasers with and without added chromophores can be used for the selective removal of dental caries from stained pit and fissures in preparation for composite sealant placement with minimal damage to sound, unstained tooth structure. Polarization sensitive optical coherence tomography (PS-OCT) is a new nondestructive imaging technology that can be used to acquire images of caries lesions in occlusal surfaces. PSOCT is ideally suited to measure the caries depth and severity before and after selective removal from occlusal surfaces. In this study, λ=355-nm laser pulses of 5-ns duration at irradiation intensities ranging from 0.5-1.3 J/cm2 were scanned across tooth surfaces to selectively remove decayed enamel with and without the addition of India ink. PS-OCT images were acquired before and after removal. The laser removal was also compared to air abrasion in order to compare selectivity of these two conservative caries removal technologies.

  17. Direct generation of 2-ps blue pulses from gain-switched InGaN VCSEL assessed by up-conversion technique.

    Science.gov (United States)

    Asahara, Akifumi; Chen, Shaoqiang; Ito, Takashi; Yoshita, Masahiro; Liu, Wenjie; Zhang, Baoping; Suemoto, Tohru; Akiyama, Hidefumi

    2014-09-19

    Ultra-short pulses in blue region generated from compact and low-cost semiconductor lasers have attracted much attention for a wide variety of applications. Nitride-based vertical-cavity surface-emitting lasers (VCSELs), having intrinsic high material gain and short cavities, favor the generation of ultra-short blue pulses via a simple gain-switching technique. In this study, we fabricated a single-mode InGaN VCSEL consisting of 10-period InGaN/GaN quantum wells (QWs). The output pulses were evaluated accurately with an up-conversion measurement system having time resolution of 0.12 ps. We demonstrated that ultra-short blue pulses, as short as 2.2 ps at 3.4 K and 4.0 ps at room temperature, were generated from the gain-switched InGaN VCSEL via impulsive optical pumping, without any post-processing. The gain-switched pulses we obtained should greatly promote the development of ultra-short blue pulse generation. In addition, this successful assessment demonstrates the up-conversion technique's usefulness for characterizing ultra-short blue pulses from semiconductor lasers.

  18. Pulsed Shortwave Diathermy and Prolonged Long-Duration Stretching Increase Dorsiflexion Range of Motion More Than Identical Stretching Without Diathermy

    OpenAIRE

    Peres, Steven E.; Draper, David O.; Knight, Kenneth L.; Ricard, Mark D.

    2002-01-01

    Objective: To compare the effects of 3 treatments on ankle dorsiflexion range of motion: prolonged long-duration stretching, pulsed shortwave diathermy followed by stretching, and pulsed shortwave diathermy, stretching, and ice combined.

  19. Comparison of membrane electroporation and protein denature in response to pulsed electric field with different durations.

    Science.gov (United States)

    Huang, Feiran; Fang, Zhihui; Mast, Jason; Chen, Wei

    2013-05-01

    In this paper, we compared the minimum potential differences in the electroporation of membrane lipid bilayers and the denaturation of membrane proteins in response to an intensive pulsed electric field with various pulse durations. Single skeletal muscle fibers were exposed to a pulsed external electric field. The field-induced changes in the membrane integrity (leakage current) and the Na channel currents were monitored to identify the minimum electric field needed to damage the membrane lipid bilayer and the membrane proteins, respectively. We found that in response to a relatively long pulsed electric shock (longer than the membrane intrinsic time constant), a lower membrane potential was needed to electroporate the cell membrane than for denaturing the membrane proteins, while for a short pulse a higher membrane potential was needed. In other words, phospholipid bilayers are more sensitive to the electric field than the membrane proteins for a long pulsed shock, while for a short pulse the proteins become more vulnerable. We can predict that for a short or ultrashort pulsed electric shock, the minimum membrane potential required to start to denature the protein functions in the cell plasma membrane is lower than that which starts to reduce the membrane integrity. Copyright © 2013 Wiley Periodicals, Inc.

  20. Experimental study of laser-induced plasma: Influence of laser fluence and pulse duration

    Energy Technology Data Exchange (ETDEWEB)

    Bai, Xueshi; Ma, Qianli; Perrier, Maxime; Motto-Ros, Vincent [Institut Lumière Matière, UMR5306 Université Lyon 1-CNRS, Université de Lyon, 69622 Villeurbanne cedex (France); Sabourdy, David; Nguyen, Luc; Jalocha, Alain [CILAS Laser Company, Photonics Department, 45000 Orléans (France); Yu, Jin, E-mail: jin.yu@univ-lyon1.fr [Institut Lumière Matière, UMR5306 Université Lyon 1-CNRS, Université de Lyon, 69622 Villeurbanne cedex (France)

    2013-09-01

    Influence of laser fluence and pulse duration on the morphology and the internal structure of plasma induced by infrared nanosecond laser pulse on an aluminum target placed in an argon ambient gas of one atmosphere pressure was experimentally studied. Dual-wavelength differential spectroscopic imaging was used in the experiment, which allowed observing the detailed structure inside of the ablation plume with distributions of species evaporated from the target as well as contributed by the ambient gas. Different regimes of post-ablation interaction were investigated using different laser fluences and pulse durations. We demonstrate in particular that plasma shielding due to various species localized in different zones inside of the plume leads to different morphologies and internal structures of the plasma. At moderate fluence, the plasma shielding due to the ablation vapor localized in the central part of the plume leads to its nearly spherical expansion with a layered structure of the distribution of different species. At higher fluence, the plasma shielding becomes strongly contributed by ionized ambient gas localized in the propagation front of the plume. An elongated morphology of the plume is observed with a zone of mixing between different species evaporated from the target or contributed by the ambient gas. Finally with extremely strong plasma shielding by ionized ambient gas in the case of a long duration pulse at high fluence, a delayed evaporation from the target is observed due to the ejection of melted material by splashing. - Highlights: • Morphology and internal structure of a plasma were experimentally determined. • Laser fluence and pulse duration are critical parameters for plasma structure. • Plasma shielding due to various species leads to different plasma structures. • Different regimes of laser-support absorption wave are used for interpretation. • Splashing ejection is observed for strong plasma shielding with long pulse.

  1. The Nature of Emission from Optical Breakdown Induced by Pulses of fs and ns Duration

    Energy Technology Data Exchange (ETDEWEB)

    Carr, C W; Feit, M D; Rubenchik, A M; Demange, P; Kucheyev, S; Shirk, M D; Radousky, H B; Demos, S G

    2004-11-09

    Spectral emission from optical breakdown in the bulk of a transparent dielectric contains information about the nature of the breakdown medium. We have made time resolved measurements of the breakdown induced emission caused by nanosecond and femtosecond infrared laser pulses. We previously demonstrated that the emission due to ns pulses is blackbody in nature allowing determination of the fireball temperature and pressure during and after the damage event. The emission due to femtosecond pulse breakdown is not blackbody in nature; two different spectral distributions being noted. In one case, the peak spectral distribution occurs at the second harmonic of the incident radiation, in the other the distribution is broader and flatter and presumably due to continuum generation. The differences between ns and fs breakdown emission can be explained by the differing breakdown region geometries for the two pulse durations. The possibility to use spectral emission as a diagnostic of the emission region morphology will be discussed.

  2. Construction of a magnetic bottle spectrometer and its application to pulse duration measurement of X-ray laser using a pump-probe method

    Directory of Open Access Journals (Sweden)

    S. Namba

    2015-11-01

    Full Text Available To characterize the temporal evolution of ultrashort X-ray pulses emitted by laser plasmas using a pump-probe method, a magnetic bottle time-of-flight electron spectrometer is constructed. The design is determined by numerical calculations of a mirror magnetic field and of the electron trajectory in a flight tube. The performance of the spectrometer is characterized by measuring the electron spectra of xenon atoms irradiated with a laser-driven plasma X-ray pulse. In addition, two-color above-threshold ionization (ATI experiment is conducted for measurement of the X-ray laser pulse duration, in which xenon atoms are simultaneously irradiated with an X-ray laser pump and an IR laser probe. The correlation in the intensity of the sideband spectra of the 4d inner-shell photoelectrons and in the time delay of the two laser pulses yields an X-ray pulse width of 5.7 ps, in good agreement with the value obtained using an X-ray streak camera.

  3. Effect of Er:YAG laser pulse duration on the shear bond strength of bleached dentin

    Science.gov (United States)

    Yu, Ping; Yu, Dandan; Zhao, Peng; Xu, Zhou; Gao, Shanshan

    2017-11-01

    The influence of different Er:YAG laser pulse durations on the shear bond strength (SBS) of bleached dentin was investigated in this study. In total, 176 crowns of extracted human premolars were cut horizontally, embedded and ground to expose the sound dentin. Of these, 132 specimens were bleached with 12% hydrogen peroxide (HP) and divided into three groups, irradiated by an Er:YAG laser with different pulse lengths of 50 µs super short pulse (SSP), 100 µs moderate short pulse (MSP) and 300 µs short pulse (SP), respectively. The energy density of the three groups was the same at about 15.73 J cm‑2 for each. Then, each group was further divided into two subgroups according to whether it had been etched with 37% phosphoric acid or not. The control group (N  =  22) was bleached and etched with acid while the blank group (N  =  22) was just etched with acid. The surface morphology of the dentin was observed using scanning electron microscopy (SEM). The SBS of the composite resin to the conditioned dentin was tested with a universal testing machine. It was found that the SBS of the dentin significantly decreased after bleaching treatment, while it was possible to restore it using Er:YAG laser irradiation. Lasers with various pulse durations led to different surface morphologies but had no effect on the SBS. The SSP laser was more suitable on account of it resulting in less thermal damage, and additional acid etching was not necessary for the irradiated bleached dentin in the clinic because it could not further improve the SBS value.

  4. Effect of shorter pulse duration in cochlear neural activation with an 810-nm near-infrared laser.

    Science.gov (United States)

    Wang, Jingxuan; Tian, Lan; Lu, Jianren; Xia, Ming; Wei, Ying

    2017-02-01

    Optical neural stimulation in the cochlea has been presented as an alternative technique to the electrical stimulation due to its potential in spatially selectivity enhancement. So far, few studies have selected the near-infrared (NIR) laser in cochlear neural stimulation and limited optical parameter space has been examined. This paper focused on investigating the optical parameter effect on NIR stimulation of auditory neurons, especially under shorter pulse durations. The spiral ganglion neurons in the cochlea of deafened guinea pigs were stimulated with a pulsed 810-nm NIR laser in vivo. The laser radiation was delivered by an optical fiber and irradiated towards the modiolus. Optically evoked auditory brainstem responses (OABRs) with various optical parameters were recorded and investigated. The OABRs could be elicited with the cochlear deafened animals by using the 810-nm laser in a wide pulse duration ranged from 20 to 1000 μs. Results showed that the OABR intensity increased along with the increasing laser radiant exposure of limited range at each specific pulse duration. In addition, for the pulse durations from 20 to 300 μs, the OABR intensity increased monotonically along with the pulse duration broadening. While for pulse durations above 300 μs, the OABR intensity basically kept stable with the increasing pulse duration. The 810-nm NIR laser could be an effective stimulus in evoking the cochlear neuron response. Our experimental data provided evidence to optimize the pulse duration range, and the results suggested that the pulse durations from 20 to 300 μs could be the optimized range in cochlear neural activation with the 810-nm-wavelength laser.

  5. Simulations of drastically reduced SBS with laser pulses composed of a Spike Train of Uneven Duration and Delay (STUD pulses

    Directory of Open Access Journals (Sweden)

    Hüller Stefan

    2013-11-01

    Full Text Available By comparing the impact of established laser smoothing techniques like Random Phase Plates (RPP and Smoothing by Spectral Dispersion (SSD to the concept of “Spike Trains of Uneven Duration and Delay” (STUD pulses on the amplification of parametric instabilities in laser-produced plasmas, we show with the help of numerical simulations, that STUD pulses can drastically reduce instability growth by orders of magnitude. The simulation results, obtained with the code Harmony in a nonuniformly flowing mm-size plasma for the Stimulated Brillouin Scattering (SBS instability, show that the efficiency of the STUD pulse technique is due to the fact that successive re-amplification in space and time of parametrically excited plasma waves inside laser hot spots is minimized. An overall mean fluctuation level of ion acoustic waves at low amplitude is established because of the frequent change of the speckle pattern in successive spikes. This level stays orders of magnitude below the levels of ion acoustic waves excited in hot spots of RPP and SSD laser beams.

  6. Fetal pulse oximetry: correlation between oxygen desaturation, duration, and frequency and neonatal outcomes.

    Science.gov (United States)

    Gorenberg, David M; Pattillo, Carol; Hendi, Pooneh; Rumney, Pamela J; Garite, Thomas J

    2003-07-01

    The purpose of this study was to identify the threshold of fetal arterial oxyhemoglobin saturation that predicts neonatal acidosis and adverse outcomes. Fetal oxygen saturation data from a published randomized controlled trial of fetal pulse oximetry were evaluated in relation to the number and duration of low fetal oxygen saturation episodes and neonatal outcomes. Fetal oxygen saturation episodes (epochs) of at least 10-second duration were categorized into the following groups: (1). or=25%, (2). or=20%, (3). 30%. One hundred seventy-four fetal heart rate tracings were identified. An analysis of mean umbilical artery pH revealed a significant difference between groups 1 and 3 compared with the control subjects. The incidence of adverse neonatal outcome was significantly greater when the number of epochs exceeded 10. An analysis of the duration of fetal oxygen saturation of 10 epochs of <30%.

  7. Electrical discharge machining (EDM) of Inconel 718 by using copper electrode at higher peak current and pulse duration

    Science.gov (United States)

    Ahmad, S.; Lajis, M. A.

    2013-12-01

    This experimental work is an attempt to investigate the performance of Copper electrode when EDM of Nickel Based Super Alloy, Inconel 718 is at higher peak current and pulse duration. Peak current, Ip and pulse duration (pulse on-time), ton are selected as the most important electrical pulse parameters. In addition, their influence on material removal rate (MRR), electrode wear rate (EWR), and surface roughness (Ra) are experimentally investigated. The ranges of 10 mm diameter of Copper electrode are used to EDM of Inconel 718. After the experiments, MRR, EWR, and Ra of the machined surfaces need to be measured in order to evaluate the performance of the EDM process. In order to obtain high MRR, higher peak current in range of 20A to 40A and pulse duration in range of 200μs to 400μs were used. Experimental results have shown that machining at a highest peak current used of 40A and the lowest pulse duration of 200μs used for the experiment yields the highest material removal rate (MRR) with value 34.94 mm3/min, whereas machining at a peak current of 20A and pulse duration of 400μs yields the lowest electrode wear rate (EWR) with value -0.0101 mm3/min. The lowest surface roughness (Ra) is 8.53 μm achieved at a lowest peak current used of 20A and pulse duration of 200μs.

  8. Time-resolved temperature and number density measurements in a repetitively pulsed nanosecond-duration discharge

    Science.gov (United States)

    Manoharan, Rounak; Boyson, Toby K.; O'Byrne, Sean

    2016-12-01

    This paper presents a fast detection technique using diode laser absorption spectroscopy as an optical diagnostic tool to measure time-resolved temperature and number density in a repetitively pulsed nanosecond-duration discharge. Argon atoms in the 1 s3 metastable state were optically probed by current scanning a vertical cavity surface emitting laser diode over the 1 s3→2 p4 transition at 794 nm. Temperature and number density measurements are presented at pulse energies from 20 μJ to 300 μJ, at a constant pressure of 2.67 kPa and 10 kHz repetition frequency. A time resolution of 2 ns was achieved for the measurements during and after the discharge pulse. We demonstrate the method used to make nanosecond resolution measurements, the precision of this technique and the effect of pulse energy on the translational temperature and number density of the metastable atoms. Our measurements show that, for small input pulse energies, the peak temperature of the argon atoms in the 1s3 state can exceed ambient room temperature by up to an order of magnitude.

  9. The influence of pulse duration on the stress levels in ablation of ceramics: A finite element study

    Energy Technology Data Exchange (ETDEWEB)

    Verde, A. Vila [Department of Physics, University of Minho, Campus de Gualtar, 4710-057 Braga (Portugal); Ramos, Marta M.D. [Department of Physics, University of Minho, Campus de Gualtar, 4710-057 Braga (Portugal)]. E-mail: marta@fisica.uminho.pt

    2006-04-30

    We present a finite element model to investigate the dynamic thermal and mechanical response of ceramic materials to pulsed infrared radiation. The model was applied to the specific problem of determining the influence of the pulse duration on the stress levels reached in human dental enamel irradiated by a CO{sub 2} laser at 10.6 {mu}m with pulse durations between 0.1 and 100 {mu}s and sub-ablative fluence. Our results indicate that short pulses with durations much larger than the characteristic acoustic relaxation time of the material can still cause high stress transients at the irradiated site, and indicate that pulse durations of the order of 10 {mu}s may be more adequate both for enamel surface modification and for ablation than pulse durations up to 1 {mu}s. The model presented here can easily be modified to investigate the dynamic response of ceramic materials to mid-infrared radiation and help determine optimal pulse durations for specific procedures.

  10. Constraints on photon pulse duration from longitudinal electron beam diagnostics at a soft x-ray free-electron laser

    Directory of Open Access Journals (Sweden)

    C. Behrens

    2012-03-01

    Full Text Available The successful operation of x-ray free-electron lasers (FELs, like the Linac Coherent Light Source or the Free-Electron Laser in Hamburg (FLASH, makes unprecedented research on matter at atomic length and ultrafast time scales possible. However, in order to take advantage of these unique light sources and to meet the strict requirements of many experiments in photon science, FEL photon pulse durations need to be known and tunable. This can be achieved by controlling the FEL driving electron beams, and high-resolution longitudinal electron beam diagnostics can be utilized to provide constraints on the expected FEL photon pulse durations. In this paper, we present comparative measurements of soft x-ray pulse durations and electron bunch lengths at FLASH. The soft x-ray pulse durations were measured by FEL radiation pulse energy statistics and compared to electron bunch lengths determined by frequency-domain spectroscopy of coherent transition radiation in the terahertz range and time-domain longitudinal phase space measurements. The experimental results, theoretical considerations, and simulations show that high-resolution longitudinal electron beam diagnostics provide reasonable constraints on the expected FEL photon pulse durations. In addition, we demonstrated the generation of soft x-ray pulses with durations below 50 fs (FWHM after the implementation of the new uniform electron bunch compression scheme used at FLASH.

  11. Effect of Reverse Pulse Current Duration on the Corrosion and Wear Performance of Ni-W Nanolaminate Coatings

    Science.gov (United States)

    Shreeram, Devesh Dadhich; Bedekar, Vikram; Li, Shengxi; Jagtap, Rohit; Cong, Hongbo; Doll, Gary L.

    2017-11-01

    The effects of varying the reverse pulse current duration ( τ = 0 s, 1 s, 5 s, and 10 s) were evaluated on the composition, crystallinity, hardness, corrosion resistance, and tribological performance of nanolaminate Ni-W coatings deposited by pulsed reverse current electrodeposition. With the deposition conditions used in this study, it was found that a reverse current duration of τ = 1 s produced a coating that was both highly corrosion resistant and wear resistant.

  12. High-repetition-rate regenerative thin-disk amplifier with 116 microJ pulse energy and 250 fs pulse duration.

    Science.gov (United States)

    Larionov, Mikhail; Butze, Frank; Nickel, Detlef; Giesen, Adolf

    2007-03-01

    A thin-disk regenerative amplifier based on Yb-doped potassium yttrium tungstate is operated at 40 kHz with an output pulse energy of 116 microJ and a pulse duration of 250 fs. Dispersive stretching of the pulse during amplification instead of an external stretcher is used to avoid high peak intensities. The small amount of the laser active material in the amplifier inherent for the thin-disk laser design and a large beam radius in the Pockels cell reduce nonlinear effects further. Consequently the output pulses can be compressed to 250 fs using a pair of diffraction gratings.

  13. Transient effects in the translation of bubbles insonated with acoustic pulses of finite duration

    Science.gov (United States)

    Igualada-Villodre, Elena; Medina-Palomo, Ana; Vega-Martínez, Patricia; Rodríguez-Rodríguez, Javier

    2018-02-01

    The translation of a bubble under the action of an acoustic forcing finds applications in fields ranging from drug delivery to sonoluminesce. This phenomenon has been widely studied for cases where the amplitude of the forcing remains constant over time. However, in many practical applications, the duration of the forcing is not long enough for the bubble to attain a constant translational velocity, mainly due to the effect of the history force. Here, we develop a formulation, valid in the limit of very viscous flow and small-amplitude acoustic forcing, that allows us to describe the transient dynamics of bubbles driven by acoustic pulses consisting of a finite number of cycles. We also present an asymptotic solution to this theory for the case of a finite-duration sinusoidal pressure pulse. This solution takes into account both the history integral term and the transient period that the bubble needs to achieve steady radial oscillations, being the former dominant during most of the acceleration process. Moreover, by introducing some additional assumptions, we derive a simplified formula that describes fairly well the time evolution of the bubble velocity. Using this solution we show that the convergence to the steady translational velocity, given by the so-called Bjerknes force, occurs rather slowly, namely as $\\tau^{-1/2}$, which explains the slow convergence of the bubble velocity and stresses the importance of taking into account the history force.

  14. Improving the spatial resolution of epiretinal implants by increasing stimulus pulse duration.

    Science.gov (United States)

    Weitz, Andrew C; Nanduri, Devyani; Behrend, Matthew R; Gonzalez-Calle, Alejandra; Greenberg, Robert J; Humayun, Mark S; Chow, Robert H; Weiland, James D

    2015-12-16

    Retinal prosthetic implants are the only approved treatment for retinitis pigmentosa, a disease of the eye that causes blindness through gradual degeneration of photoreceptors. An array of microelectrodes triggered by input from a camera stimulates surviving retinal neurons, with each electrode acting as a pixel. Unintended stimulation of retinal ganglion cell axons causes patients to see large oblong shapes of light, rather than focal spots, making it difficult to perceive forms. To address this problem, we performed calcium imaging in isolated retinas and mapped the patterns of cells activated by different electrical stimulation protocols. We found that pulse durations two orders of magnitude longer than those typically used in existing implants stimulated inner retinal neurons while avoiding activation of ganglion cell axons, thus confining retinal responses to the site of the electrode. Multielectrode stimulation with 25-ms pulses can pattern letters on the retina corresponding to a Snellen acuity of 20/312. We validated our findings in a patient with an implanted epiretinal prosthesis by demonstrating that 25-ms pulses evoke focal spots of light. Copyright © 2015, American Association for the Advancement of Science.

  15. Duration of an intense laser pulse can determine the breakage of multiple chemical bonds.

    Science.gov (United States)

    Xie, Xinhua; Lötstedt, Erik; Roither, Stefan; Schöffler, Markus; Kartashov, Daniil; Midorikawa, Katsumi; Baltuška, Andrius; Yamanouchi, Kaoru; Kitzler, Markus

    2015-08-14

    Control over the breakage of a certain chemical bond in a molecule by an ultrashort laser pulse has been considered for decades. With the availability of intense non-resonant laser fields it became possible to pre-determine femtosecond to picosecond molecular bond breakage dynamics by controlled distortions of the electronic molecular system on sub-femtosecond time scales using field-sensitive processes such as strong-field ionization or excitation. So far, all successful demonstrations in this area considered only fragmentation reactions, where only one bond is broken and the molecule is split into merely two moieties. Here, using ethylene (C2H4) as an example, we experimentally investigate whether complex fragmentation reactions that involve the breakage of more than one chemical bond can be influenced by parameters of an ultrashort intense laser pulse. We show that the dynamics of removing three electrons by strong-field ionization determines the ratio of fragmentation of the molecular trication into two respectively three moieties. We observe a relative increase of two-body fragmentations with the laser pulse duration by almost an order of magnitude. Supported by quantum chemical simulations we explain our experimental results by the interplay between the dynamics of electron removal and nuclear motion.

  16. Sub-100 ps laser-driven dynamic compression of solid deuterium with a ~40 μ J laser pulse

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Michael R.; Crowhurst, Jonathan C.; Bastea, Sorin; Zaug, Joseph M.; Goncharov, Alexander F.

    2014-07-14

    We dynamically compress solid deuterium over <100 ps from initial pressures of 22 GPa to 55 GPa, to final pressures as high as 71 GPa, with <40 μJ of pulse energy. At 25 GPa initial pressure, we measure compression wave speeds consistent with quasi-isentropic compression and a 24% increase in density. The laser drive energy per unit density change is 109 times smaller than it is for recent longer (~30 ns) time scale compression experiments. This suggests that, for a given final density, dynamic compression of hydrogen might be achieved using orders of magnitude lower laser energy than currently used.

  17. Pulse duration and wavelength effects in laser scribing of thin-film polycrystalline PV materials

    Science.gov (United States)

    Compaan, A. D.; Matulionis, I.; Nakade, S.; Jayamaha, U.

    1997-02-01

    This project is focussed on a study of wavelength-dependent effects and pulse-duration effects on laser scribing of polycrystalline thin-film PV materials. The materials studied here are CdTe, CI(G)S, SnO2, ZnO, molybdenum and gold. This paper provides a summary of thresholds and optimum scribing energy densities for two types of Nd:YAG lasers, a 308 nm excimer laser, and a copper vapor laser. A comparison is presented of glass-side vs. film-side scribing. Discussion is also given of scribing of multilayer films such as ZnO/CIS/moly and gold/CdTe/SnO2.

  18. Cavity-enhanced absorption spectroscopy with a ps-pulsed UV laser for sensitive, high-speed measurements in a shock tube.

    Science.gov (United States)

    Wang, Shengkai; Sun, Kai; Davidson, David F; Jeffries, Jay B; Hanson, Ronald K

    2016-01-11

    We report the first application of cavity-enhanced absorption spectroscopy (CEAS) with a ps-pulsed UV laser for sensitive and rapid gaseous species time-history measurements in a transient environment (in this study, a shock tube). The broadband nature of the ps pulses enabled instantaneous coupling of the laser beam into roughly a thousand cavity modes, which grants excellent immunity to laser-cavity coupling noise in environments with heavy vibrations, even with an on-axis alignment. In this proof-of-concept experiment, we demonstrated an absorption gain of 49, which improved the minimum detectable absorbance by ~20 compared to the conventional single-pass strategy at similar experimental conditions. For absorption measurements behind reflected shock waves, an effective time-resolution of ~2 μs was achieved, which enabled time-resolved observations of transient phenomena, such as the vibrational relaxation of O(2) demonstrated here. The substantial improvement in detection sensitivity, together with microsecond measurement resolution implies excellent potential for studies of transient physical and chemical processes in nonequilibrium situations, particularly via measurements of weak absorptions of trace species in dilute reactive systems.

  19. Effect of pulse duration and pulse repetition frequency of cavitation histotripsy on erosion at the surface of soft material.

    Science.gov (United States)

    Zhou, Yufeng; Wang, Xiaotong

    2018-03-01

    Cavitation histotripsy with the short pulse duration (PD) but high pulse repetition frequency (PRF) disintegrates the tissue at a fluid interface. However, longer PD and lower PRF are used in the other focused ultrasound applications, where the acoustic radiation force, streaming, and cavitation are different, and their effects on erosion are unknown. In this study, the erosion at the surface of phantom/ex vivo tissue and the characteristics of induced bubble cloud captured by high-speed photography, passive cavitation detection, and light transmission during histotripsy exposure at varied PDs and PRFs but the same duty cycle were compared. The peak negative pressure of 6.6 MPa at the PD of 20 ms and PRF of 1 Hz began to erode the phantom, which becomes more significant with the increase of peak negative pressure, PD, and interval time between bursts. The increase of the PRF from 1 Hz to 1000 Hz, while the decrease of the PD from 20 ms to 20 μs (duty cycle of 2%) at the same energy was delivered to the gel phantom immersed in the degassed water led to the decrease of erosion volume but a slight increase of the erosion area and smoother surface. Low PRF and long PD produce the significant tissue deformation, acoustic wave refocusing, confinement of bubbles in a conical region, and more bubble dissolution after the collapse for the high acoustic scattering and light transmission signals. In comparison, high PRF and low PD produce a wide distribution of bubbles with only little wave refocusing at the beginning of cavitation histotripsy and high inertial cavitation. Acoustic emission dose has a good correlation with the erosion volume. The erosion on the porcine kidney at the varied PRFs and PDs with the same energy output showed similar trends as those in the phantom but at a slow rate. In summary, the PRF and PD are important parameters for the cavitation histotripsy-induced erosion at the interface of fluid and soft material, and they should be

  20. Strength-duration curves of fixed pulse width variable tilt truncated exponential waveforms for nonthoracotomy internal defibrillation in dogs.

    Science.gov (United States)

    Chapman, P D; Wetherbee, J N; Vetter, J W; Troup, P; Souza, J

    1988-07-01

    Six anesthetized dogs (wgt 19.6 + 1.1 kg) underwent defibrillation trials using truncated monophasic pulses of 2.5-20 msec in duration. The current pathway consisted of a 4 cm2 RV catheter electrode (cathode) and a 13.9 cm2 subcutaneous chest wall patch (anode). Fibrillation was induced by alternating current and defibrillation attempted 10 seconds later. Only one test shock was assessed for each fibrillation episode. The various durations were tested randomly, and the minimum peak voltage and energy resulting in defibrillation was determined for each. Shorter pulse durations were associated with lower energies with pulses of 2.5-15 msec having significantly lower energy thresholds than shocks of 20 msec (P less than 0.05). The relationship between duration and voltage threshold is hyperbolic with minimum voltage between 7.5 and 12.5 msec while the shortest and longest pulses were associated with the highest voltage thresholds. Shocks of 5 to 15 msec were associated with significantly lower voltage threshold than 2.5 msec pulses (P less than 0.05). The threshold average current (Iav) reached a nadir at 10 msec. Shocks in the midrange of those tested resulted in the best combination of low average current and energy requirements for defibrillation using this nonthoracotomy lead system.

  1. An image-brightness amplifier based on copper bromide vapor for operation at increased superradiance pulse duration

    Science.gov (United States)

    Trigub, M. V.; Vlasov, V. V.; Torgaev, S. N.; Evtushenko, G. S.

    2017-09-01

    We present data on the development and application of an image-brightness amplifier based on copper bromide vapor intended for the visualization of objects occurring at distances above 5 m from the detecting equipment. An increase in the superradiance (gain) pulse duration was achieved by decreasing the repetition frequency of pumping pulses (to 3 kHz) and increasing the capacitance of the capacitor bank (up to 3.4 nF) so as to increase the deposited pulse energy. The basic possibility of creating active optical systems with brightness amplifiers (laser monitors) for the visualization of objects and processes occurring at large distances from a registration system is demonstrated.

  2. Variable pulsewidth erbium:YAG laser ablation of the ureter and urethra in vitro and in vivo: optimization of the laser fluence, pulse duration, and pulse repetition rate

    Science.gov (United States)

    Fried, Nathaniel M.; Tesfaye, Zelalem; Ong, Albert M.; Rha, Koon H.; Hejazi, Pooya

    2004-07-01

    Stricture recurrence frequently occurs due to mechanical or thermal insult during endourologic treatment of ureteral and urethral strictures. Optimization of the Er:YAG laser for precise incision of strictures was conducted using ureteral and urethral tisssue samples, ex vivo, and a laparoscopic porcine ureteral model with exposed ureter, in vivo. Erbium:YAG laser radiation with a wavelength of 2.94 microns, pulse lengths of 8, 70, and 220 microseconds, output energies of 2 - 35 mJ, fluences of 1 - 25 J/cm2, and pulse repetition rates of 5 - 30 Hz, was delivered through germanium oxide optical fibers in contact with the tissue. Incision of the ureteral wall was achieved in vivo with less than 20 pulses at a laser fluence of 4 J/cm2. Thermal damage was reduced from 30 - 60 microns to 10 - 20 microns by shortening the laser pulse duration from 220 to 70 microseconds. Pulse repetition rates above 20 Hz resulted in larger thermal damage zones ranging from 60 - 120 microns. The Er:YAG laser, operating at a pulse duration of approximately 70 microseconds, a fluence of 4 J/cm2 or greater, and a repetition rate less than 20 Hz, is capable of rapidly incising urethral and ureteral tissues, in vivo, with minimal thermal and mechanical side-effects.

  3. Sub-100 ps laser-driven dynamic compression of solid deuterium with a ∼40 μJ laser pulse

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Michael R., E-mail: armstrong30@llnl.gov; Crowhurst, Jonathan C.; Bastea, Sorin; Zaug, Joseph M. [Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Goncharov, Alexander F. [2Geophysical Laboratory, Carnegie Institute of Washington, Washington, DC 20015 (United States)

    2014-07-14

    We dynamically compress solid deuterium over <100 ps from initial pressures of 22 GPa to 55 GPa, to final pressures as high as 71 GPa, with <40 μJ of pulse energy. At 25 GPa initial pressure, we measure compression wave speeds consistent with quasi-isentropic compression and a 24% increase in density. The laser drive energy per unit density change is 10{sup 9} times smaller than it is for recent longer (∼30 ns) time scale compression experiments. This suggests that, for a given final density, dynamic compression of hydrogen might be achieved using orders of magnitude lower laser energy than currently used.

  4. Reduction of the pulse duration of the ultrafast laser pulses of the Two-Photon Laser Scanning Microscopy (2PLSM

    Directory of Open Access Journals (Sweden)

    Reshak Ali

    2008-07-01

    Full Text Available Abstract Background We provide an update of our two-photon laser scanning microscope by compressing or reducing the broadening of the pulse width of ultrafast laser pulses for dispersion precompensation, to enable the pulses to penetrate deeply inside the sample. Findings The broadening comes as the pulses pass through the optical elements. We enhanced and modified the quality and the sharpness of images by enhancing the resolution using special polarizer namely Glan Laser polarizer GL10. This polarizer consists of two prisms separated by air space. This air separation between the two prisms uses to delay the red wavelength when the light leaves the first prism to the air then to second prism. We note a considerable enhancing with using the GL polarizer, and we can see the details of the leaf structure in early stages when we trying to get focus through z-stacks of images in comparison to exactly the same measurements without using GL polarizer. Hence, with this modification we able to reduce the time of exposure the sample to the laser radiation thereby we will reduce the probability of photobleaching and phototoxicity. When the pulse width reduced, the average power of the laser pulses maintained at a constant level. Significant enhancement is found between the two kinds of images of the Two-Photon Excitation Fluorescence (TPEF. Conclusion In summary reduction the laser pulse width allowed to collect more diffraction orders which will used to form the images. The more diffraction orders the higher resolution images.

  5. Pulse generation and compression using an asymmetrical porous ...

    Indian Academy of Sciences (India)

    We propose an asymmetrical Mach–Zehnder interferometer (MZI) for efficient pulse generation and compression using porous silicon (PS) waveguide, fibre delay line and couplers. We show a pulse compression of about 0.4 ns at the output port with third-order super-Gaussian input pulse in ∼2 ns time duration and ∼40.3 ...

  6. Applying short-duration pulses as a mean to enhance volatile organic compounds removal by air sparging

    Science.gov (United States)

    Ben Neriah, Asaf; Paster, Amir

    2017-10-01

    Application of short-duration pulses of high air pressure, to an air sparging system for groundwater remediation, was tested in a two-dimensional laboratory setup. It was hypothesized that this injection mode, termed boxcar, can enhance the remediation efficiency due to the larger ZOI and enhanced mixing which results from the pressure pulses. To test this hypothesis, flow and transport experiments were performed. Results confirm that cyclically applying short-duration pressure pulses may enhance contaminant cleanup. Comparing the boxcar to conventional continuous air-injection shows up to a three-fold increase in the single well radius of influence, dependent on the intensity of the short-duration pressure-pulses. The cleanup efficiency of Toluene from the water was 95% higher than that achieved under continuous injection with the same average conditions. This improvement was attributed to the larger zone of influence and higher average air permeability achieved in the boxcar mode, relative to continuous sparging. Mixing enhancement resultant from recurring pressure pulses was suggested as one of the mechanisms which enhance the contaminant cleanup. The application of a boxcar mode in an existing, multiwell, air sparging setup can be relatively straightforward: it requires the installation of an on-off valve in each of the injection-wells and a central control system. Then, turning off some of the wells, for a short-duration, result in a stepwise increase in injection pressure in the rest of the wells. It is hoped that this work will stimulate the additional required research and ultimately a field scale application of this new injection mode.

  7. Improved sonothrombolysis from a modified diagnostic transducer delivering impulses containing a longer pulse duration.

    Science.gov (United States)

    Wu, Juefei; Xie, Feng; Kumar, Tanmay; Liu, Jinjin; Lof, John; Shi, William; Everbach, E Carr; Porter, Thomas R

    2014-07-01

    Although guided high-mechanical-index (MI) impulses from a diagnostic ultrasound transducer have been used in preclinical studies to dissolve coronary arterial and microvascular thrombi in the presence of intravenously infused microbubbles, it is possible that pulse durations (PDs) longer than that used for diagnostic imaging may further improve the effectiveness of this approach. By use of an established in vitro model flow system, a total of 90 occlusive porcine arterial thrombi (thrombus age: 3-4 h) within a vascular mimicking system were randomized to 10-min treatments with two different PDs (5 and 20 μs) using a Philips S5-1 transducer (1.6-MHz center frequency) at a range of MIs (from 0.2 to 1.4). All impulses were delivered in an intermittent fashion to permit microbubble replenishment within the thrombosed vessel. Diluted lipid-encapsulated microbubbles (0.5% Definity) were infused during the entire treatment period. A tissue-mimicking phantom 5 cm thick was placed between the transducer and thrombosed vessel to mimic transthoracic attenuation. Two 20-MHz passive cavitation detection systems were placed confocal to the insonified vessel to assess for inertial cavitational activity. Percentage thrombus dissolution was calculated by weighing the thrombi before and after each treatment. Percentage thrombus dissolution was significantly higher with a 20-μs PD already at the 0.2 and 0.4 MI therapeutic impulses (54 ± 12% vs. 33 ± 17% and 54 ± 22% vs. 34 ± 17%, p dissolution decreased most likely from high-intensity cavitation shielding of the thrombus. Slightly prolonging the PD on a diagnostic transducer improves the degree of sonothrombolysis that can be achieved without fibrinolytic agents at a lower mechanical index. Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  8. TiO{sub 2} nanoparticles obtained by laser ablation in water: Influence of pulse energy and duration on the crystalline phase

    Energy Technology Data Exchange (ETDEWEB)

    Giorgetti, E., E-mail: emilia.giorgetti@fi.isc.cnr.it [Istituto dei Sistemi Complessi (ISC) CNR, Via Madonna del Piano 10, 50019 Sesto Fiorentino (Italy); Muniz Miranda, M.; Caporali, S. [Dipartimento di Chimica “Ugo Schiff”, Università di Firenze, Via della Lastruccia 3, 50019 Sesto Fiorentino (Italy); Canton, P. [Dipartimento di Scienze Molecolari e Nanosistemi, Università Ca’ Foscari, Via Torino, 30170 Venezia-Mestre (Italy); Marsili, P. [Istituto dei Sistemi Complessi (ISC) CNR, Via Madonna del Piano 10, 50019 Sesto Fiorentino (Italy); Dipartimento di Fisica, Università di Pisa, Largo Bruno Pontecorvo 3, 56127 Pisa (Italy); Vergari, C.; Giammanco, F. [Dipartimento di Fisica, Università di Pisa, Largo Bruno Pontecorvo 3, 56127 Pisa (Italy)

    2015-09-15

    Highlights: • Laser ablation of Ti in water at 1064 nm and comparison of ns and ps temporal regimes. • Structural and spectroscopic characterization of the colloids: TiO{sub 2} is the predominant phase. • Determination of an energy window where ps ablation produces more anatase than rutile. • Modelling of the experimental dependence of anatase/rutile yield on pulse length and energy. - Abstract: We fabricated Ti oxide nanoparticles by laser ablation of a Ti target in doubly deionized water with ps or ns pulses at a laser wavelength of 1064 nm. Electron microscopy, Raman, X-ray diffraction and X-ray photoelectron spectroscopy showed that, while with ns pulses the dominant oxide phase is rutile, with ps pulses anatase is the most abundant form in an intermediate energy window centered around 25 mJ per pulse. This experimental behavior can be described by a theoretical model which calculates the pressure and temperature evolution of the ablated material and, from this, the rutile and anatase yield.

  9. Diode-pumped Kerr-lens mode-locked Yb:LYSO laser with 61fs pulse duration.

    Science.gov (United States)

    Tian, Wenlong; Wang, Zhaohua; Wei, Long; Peng, Yingnan; Zhang, Jinwei; Zhu, Zheng; Zhu, Jiangfeng; Han, Hainian; Jia, Yulei; Zheng, Lihe; Xu, Jun; Wei, Zhiyi

    2014-08-11

    A stable diode pumped Kerr-lens mode-locked (KLM) Yb:LuYSiO5 (Yb:LYSO) laser of generating 61 fs pulses at a central wavelength of 1055.4 nm is experimentally demonstrated. This is, to the best of our knowledge, the first demonstration of femtosecond KLM operation in Yb:LYSO laser, and it is believed that 61 fs is the shortest pulse duration ever produced from an Yb-doped orthosilicate laser. The average output power of the mode-locked laser is 40 mW and the repetition rate is 113 MHz.

  10. Nitriding molybdenum: Effects of duration and fill gas pressure when using 100-Hz pulse DC discharge technique

    Science.gov (United States)

    Ikhlaq, U.; R., Ahmad; Shafiq, M.; Saleem, S.; S. Shah, M.; Hussain, T.; A. Khan, I.; K., Abbas; S. Abbas, M.

    2014-10-01

    Molybdenum is nitrided by a 100-Hz pulsed DC glow discharge technique for various time durations and fill gas pressures to study the effects on the surface properties of molybdenum. X-ray diffractometry (XRD), scanning electron microscopy (SEM), and atomic force microscopy (AFM) are used for the structural and morphological analysis of the nitrided layers. Vickers' microhardness tester is utilized to investigate surface microhardness. Phase analysis shows the formation of more molybdenum nitride molecules for longer nitriding durations at fill gas pressures of 2 mbar and 3 mbar (1 bar = 105 Pa). A considerable increase in surface microhardness (approximately by a factor of 2) is observed for longer duration (10 h) and 2-mbar pressure. Longer duration (10 h) and 2-mbar fill gas pressure favors the formation of homogeneous, smooth, hard layers by the incorporation of more nitrogen.

  11. Pulsed Shortwave Diathermy and Prolonged Long-Duration Stretching Increase Dorsiflexion Range of Motion More Than Identical Stretching Without Diathermy.

    Science.gov (United States)

    Peres, Steven E; Draper, David O; Knight, Kenneth L; Ricard, Mark D

    2002-03-01

    OBJECTIVE: To compare the effects of 3 treatments on ankle dorsiflexion range of motion: prolonged long-duration stretching, pulsed shortwave diathermy followed by stretching, and pulsed shortwave diathermy, stretching, and ice combined. DESIGN AND SETTING: A 2 x 5 x 15 repeated-measures (on 2 factors) design guided this study. Range-of-motion change in triceps surae flexibility was the dependent variable. The 3 independent variables were treatment group, pretest and posttest measurements, and day. Treatment group had 4 levels: control, stretching (10 minutes of stretching via the weight and pulley), diathermy and stretching (20 minutes of diathermy and 10 minutes of stretching), and diathermy, stretching, and ice (20 minutes of diathermy, 10 minutes of stretching applied after 15 minutes of diathermy, and 5 minutes of ice applied during the last 5 minutes of stretching). Each subject received 14 treatments throughout 3 weeks, with a follow-up measurement taken 6 days after the last treatment. SUBJECTS: Forty-four healthy college-student volunteers not involved in any flexibility program. MEASUREMENTS: We measured ankle dorsiflexion using a digital inclinometer before and after treatment. RESULTS: After 14 days of treatment, the range-of-motion increase was greater after heat and stretching than after stretching alone. After 6 additional days of rest, the heat and stretching range-of-motion increase was greater than that for stretching alone. CONCLUSION: Pulsed shortwave diathermy application before prolonged long-duration static stretching was more effective than stretching alone in increasing flexibility throughout 3 weeks. After 14 treatments, prolonged long-duration stretching combined with pulsed shortwave diathermy followed by ice application caused greater immediate and net range-of-motion increases than prolonged long-duration stretching alone.

  12. Pulsed Shortwave Diathermy and Prolonged Long-Duration Stretching Increase Dorsiflexion Range of Motion More Than Identical Stretching Without Diathermy

    Science.gov (United States)

    Peres, Steven E.; Draper, David O.; Knight, Kenneth L.; Ricard, Mark D.

    2002-01-01

    Objective: To compare the effects of 3 treatments on ankle dorsiflexion range of motion: prolonged long-duration stretching, pulsed shortwave diathermy followed by stretching, and pulsed shortwave diathermy, stretching, and ice combined. Design and Setting: A 2 × 5 × 15 repeated-measures (on 2 factors) design guided this study. Range-of-motion change in triceps surae flexibility was the dependent variable. The 3 independent variables were treatment group, pretest and posttest measurements, and day. Treatment group had 4 levels: control, stretching (10 minutes of stretching via the weight and pulley), diathermy and stretching (20 minutes of diathermy and 10 minutes of stretching), and diathermy, stretching, and ice (20 minutes of diathermy, 10 minutes of stretching applied after 15 minutes of diathermy, and 5 minutes of ice applied during the last 5 minutes of stretching). Each subject received 14 treatments throughout 3 weeks, with a follow-up measurement taken 6 days after the last treatment. Subjects: Forty-four healthy college-student volunteers not involved in any flexibility program. Measurements: We measured ankle dorsiflexion using a digital inclinometer before and after treatment. Results: After 14 days of treatment, the range-of-motion increase was greater after heat and stretching than after stretching alone. After 6 additional days of rest, the heat and stretching range-of-motion increase was greater than that for stretching alone. Conclusion: Pulsed shortwave diathermy application before prolonged long-duration static stretching was more effective than stretching alone in increasing flexibility throughout 3 weeks. After 14 treatments, prolonged long-duration stretching combined with pulsed shortwave diathermy followed by ice application caused greater immediate and net range-of-motion increases than prolonged long-duration stretching alone. PMID:12937443

  13. Effect of adjusting pulse durations of functional electrical stimulation cycling on energy expenditure and fatigue after spinal cord injury.

    Science.gov (United States)

    Gorgey, Ashraf S; Poarch, Hunter J; Dolbow, David D; Castillo, Teodoro; Gater, David R

    2014-01-01

    The purpose of the current study was to determine the effects of three different pulse durations (200, 350, and 500 microseconds [P200, P350, and P500, respectively]) on oxygen uptake (VO2), cycling performance, and energy expenditure (EE) percentage of fatigue of the knee extensor muscle group immediately and 48 to 72 h after cycling in persons with spinal cord injury (SCI). A convenience sample of 10 individuals with motor complete SCI participated in a repeated-measures design using a functional electrical stimulation (FES) cycle ergometer over a 3 wk period. There was no difference among the three FES protocols on relative VO2 or cycling EE. Delta EE between exercise and rest was 42% greater in both P500 and P350 compared with P200 (p = 0.07), whereas recovery VO2 was 23% greater in P350 compared with P200 (p = 0.03). There was no difference in the outcomes of the three pulse durations on muscle fatigue. Knee extensor torque significantly decreased immediately after (p < 0.001) and 48 to 72 h after (p < 0.001) FES leg cycling. Lengthening pulse duration did not affect submaximal or relative VO2 or EE, total EE, and time to fatigue. Greater recovery VO2 and delta EE were noted in P350 and P500 compared with P200. An acute bout of FES leg cycling resulted in torque reduction that did not fully recover 48 to 72 h after cycling.

  14. Laser stimulation of the auditory system at 1.94 μm and microsecond pulse durations

    Science.gov (United States)

    Izzo, Agnella D.; Walsh, Joseph T., Jr.; Ralph, Heather; Webb, Jim; Wells, Jonathon; Bendett, Mark; Richter, Claus-Peter

    2008-02-01

    Light can artificially stimulate nerve activity in vivo. A significant advantage of optical neural stimulation is the potential for higher spatial selectivity when compared with electrical stimulation. An increased spatial selectivity of stimulation could improve significantly the function of neuroprosthetics, such as cochlear implants. Cochlear implants restore a sense of hearing and communication to deaf individuals by directly electrically stimulating the remaining neural cells in the cochlea. However, performance is limited by overlapping electric fields from neighboring electrodes. Here, we report on experiments with a new laser, offering a previously unavailable wavelength, 1.94μm, and pulse durations down to 5μs, to stimulate cochlear neurons. Compound action potentials (CAP) were evoked from the gerbil cochlea with pulse durations as short as 1μs. Data show that water absorption of light is a significant factor in optical stimulation, as evidenced by the required distance between the optical fiber and the neurons during stimulation. CAP threshold measurements indicate that there is an optimal range of pulse durations over which to deposit the laser energy, less than ~100μs. The implications of these data could direct further research and design of an optical cochlear implant.

  15. Effect of laser pulse duration on damage to metal mirrors for laser IFE

    Science.gov (United States)

    Pulsifer, John E.; Tillack, Mark S.; Harilal, S. S.

    2008-01-01

    A Grazing Incidence Metal Mirror (GIMM) is a chief candidate for beam delivery for Inertial Fusion Energy (IFE). The goal for GIMM survival is greater than 3×10 8 laser pulses with 5 J/cm2 laser fluence normal to the incident beam. Laser-induced damage to metal mirrors is primarily a thermomechanical process. Long-term exposure leads to microstructural evolution analogous to fatigue. We have performed laser-induced damage experiments on high damage threshold aluminum mirrors using commercial KrF excimer (248 nm) lasers. We have studied mirror response to standard, 25 ns long-pulses as well as to IFE prototypic, 5 ns short-pulses achieved using a Pockels Cell. Short-pulse damage fluence was found to be better than predicted using simple thermal diffusion scaling from long-pulse results.

  16. 140-fs duration and 60-W peak power blue-violet optical pulses generated by a dispersion-compensated GaInN mode-locked semiconductor laser diode using a nonlinear pulse compressor.

    Science.gov (United States)

    Kono, Shunsuke; Watanabe, Hideki; Koda, Rintaro; Fuutagawa, Noriyuki; Narui, Hironobu

    2015-12-14

    Blue-violet optical pulses of 140-fs duration and 60-W peak power were obtained from a dispersion-compensated GaInN mode-locked semiconductor laser diode using a nonlinear pulse compression technique. Wavelength-dependent group velocity dispersion expressed by third-order phase dispersion was applied to the optical pulses using a pulse compressor with a spatial light modulator. The obtained optical pulses had the shortest duration ever obtained for a mode-locked semiconductor laser diode using edge-emitting type devices.

  17. Optimal control of laser plasma instabilities using Spike Trains of Uneven Duration and Delay (STUD pulses for ICF and IFE

    Directory of Open Access Journals (Sweden)

    Afeyan Bedros

    2013-11-01

    Full Text Available An adaptive method of controlling parametric instabilities in laser produced plasmas is proposed. It involves fast temporal modulation of a laser pulse on the fastest instability's amplification time scale, adapting to changing and unknown plasma conditions. These pulses are comprised of on and off sequences having at least one or two orders of magnitude contrast between them. Such laser illumination profiles are called STUD pulses for Spike Trains of Uneven Duration and Delay. The STUD pulse program includes scrambling the speckle patterns spatially in between the laser spikes. The off times allow damping of driven waves. The scrambling of the hot spots allows tens of damping times to elapse before hot spot locations experience recurring high intensity spikes. Damping in the meantime will have healed the scars of past growth. Another unique feature of STUD pulses on crossing beams is that their temporal profiles can be interlaced or staggered, and their interactions thus controlled with an on-off switch and a dimmer.

  18. An investigation of fatigue phenomenon in the upper limb muscle due to short duration pulses in an FES system

    Science.gov (United States)

    Naeem, Jannatul; Wong Azman, Amelia; Khan, Sheroz; Mohd Mustafah, Yasir

    2013-12-01

    Functional Electrical Stimulation (FES) is a method of artificially stimulating muscles or nerves in order to result in contraction or relaxation of muscles. Many studies have shown that FES system has helped patients to live a better lives especially those who are suffering from physical mobility. Unfortunately, one of the main limitations of an FES system besides of its high cost is largely due to muscle fatigue. Muscle fatigue will affect the training duration which could delay patients' recovery rate. In this paper, we analyzed the occurrence of this fatigue phenomenon in terms of stimulator parameters such as amplitude, frequency, pulse width and pulse shape. The objective of this investigation is to identify other key features of the FES system parameters in order to prolong the training duration among patients. The experiment has been done on a healthy person for the duration of one minute and later the muscles response will be observed. Resultant muscle response is recorded as force using force resistive sensor. The experimental results show muscles will get fatigue at a different rate as the frequency increases. The experiment also shows that the duty cycle is reciprocal to the resultant force.

  19. Pulse wave reflection is associated with diabetes duration, albuminuria and cardiovascular disease in type 1 diabetes

    DEFF Research Database (Denmark)

    Theilade, Simone; Lajer, Maria; Hansen, Tine Willum

    2014-01-01

    , and smoking. RESULTS: AP and AI75 measurements were available in 636 (94.1 %) patients and were 9.9 ± 7.6 mmHg and 16.9 ± 12.0, respectively. After adjustment, AP and AI75 were independently associated with diabetes duration and albuminuria (p ≤ 0.001). Furthermore, higher AP and AI75 were associated...... with diabetes duration, albuminuria, and CVD, independently of conventional risk factors. ClinicalTrials.gov:NCT01171248....

  20. Peculiarities of Efficient Plasma Generation in Air and Water by Short Duration Laser Pulses

    Science.gov (United States)

    Adamovsky, Grigory; Floyd, Bertram M.

    2017-01-01

    We have conducted experiments to demonstrate an efficient generation of plasma discharges by focused nanosecond pulsed laser beams in air and provided recommendations on the design of optical systems to implement such plasma generation. We have also demonstrated generation of the secondary plasma discharge using the unused energy from the primary one. Focused nanosecond pulsed laser beams have also been utilized to generate plasma in water where we observed self-focusing and filamentation. Furthermore, we applied the laser generated plasma to the decomposition of methylene blue dye diluted in water.

  1. Low-loss flake-graphene saturable absorber mirror for laser mode-locking at sub-200-fs pulse duration

    CERN Document Server

    Cunning, B V; Kielpinski, D

    2011-01-01

    Saturable absorbers are a key component for mode-locking femtosecond lasers. Polymer films containing graphene flakes have recently been used in transmission as laser mode-lockers, but suffer from high nonsaturable loss, limiting their application in low-gain lasers. Here we present a saturable absorber mirror based on a film of pure graphene flakes. The device is used to mode lock an erbium-doped fiber laser, generating pulses with state-of-the-art, sub-200-fs duration. The laser characteristic indicate that the film exhibits low nonsaturable loss (13% per pass) and large absorption modulation depth (45% of low-power absorption).

  2. Flexible control of femtosecond pulse duration and separation using an emittance-spoiling foil in x-ray free-electron lasers

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Y. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Behrens, C. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Coffee, R. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Decker, F. -J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Emma, P. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Field, C. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Helml, W. [Technische Univ. Munchen, Garching (Germany); Huang, Z. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Krejcik, P. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Krzywinski, J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Loos, H. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Lutman, A. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Marinelli, A. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Maxwell, T. J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Turner, J. [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2015-06-22

    We report experimental studies of generating and controlling femtosecond x-ray pulses in free-electron lasers (FELs) using an emittance spoiling foil. By selectivity spoiling the transverse emittance of the electron beam, the output pulse duration or double-pulse separation is adjusted with a variable size single or double slotted foil. Measurements were performed with an X-band transverse deflector located downstream of the FEL undulator, from which both the FEL lasing and emittance spoiling effects are observed directly.

  3. Effect of tidal volume, sampling duration, and cardiac contractility on pulse pressure and stroke volume variation during positive-pressure ventilation.

    Science.gov (United States)

    Kim, Hyung Kook; Pinsky, Michael R

    2008-10-01

    Both pulse pressure variation and stroke volume variation during intermittent positive-pressure ventilation predict preload responsiveness. However, because ventilatory and cardiac frequencies are not the same, increasing the number of breaths sampled may increase calculated pulse pressure variation and stroke volume variation because larger (max) and smaller (min) pulse pressure and stroke volume may occur. Tidal volume and contractility may also alter pulse pressure variation and stroke volume variation. We hypothesized that the magnitude of pulse pressure variation would increase with sampling duration, and that both tidal volume and contractility would independently alter pulse pressure variation and stroke volume variation. In seven pentobarbital-anesthetized intact dogs arterial and left ventricular pressure (Millar) and left ventricular volume (Leycom) were measured over 8 intermittent positive-pressure ventilation breaths at tidal volume of 5, 10, 15, and 20 mL/kg (f = 20/min, 40% inspiratory time) under baseline, esmolol (2 mg/min), dobutamine infusions (5 microg/kg/min) and following volume loading (500 mL NaCl). Stroke volume variation was calculated using pulse contour method (PiCCO, Pulsion Medical Systems, Munich, Germany) averaged over 12 secs. Pulse pressure variation was calculated as 100 x (PPmax - PPmin)/PPmean and calculated over 1, 2, 3, 4, 5, 6, 7, or 8 breaths. Pulse pressure variation increased progressively with increasing sampling duration up to but not exceeding five breaths. The effect on sampling duration was increased by greater tidal volume. Esmolol infusion decreased both pulse pressure variation and stroke volume variation as compared with baseline (p variation or stroke volume variation. Sampling duration, tidal volume, and beta-adrenergic blockade differentially alters pulse pressure variation and stroke volume variation during intermittent positive-pressure ventilation. Thus, separate validation is required to define threshold

  4. Control of ultrafast pulse propagation in semiconductor components

    DEFF Research Database (Denmark)

    Poel, Mike van der; Hansen, Per Lunnemann; Mørk, Jesper

    2009-01-01

    Time shifting of optical pulses with duration in the range from 100 fs to a few ps represents one extreme of slow light, where THz bandwidth for the slow down or speed up is necessary. The physics of the time shifting of such very short pulses involves the gain saturation of the optical medium...

  5. Effects of biphasic current pulse frequency, amplitude, duration, and interphase gap on eye movement responses to prosthetic electrical stimulation of the vestibular nerve.

    Science.gov (United States)

    Davidovics, Natan S; Fridman, Gene Y; Chiang, Bryce; Della Santina, Charles C

    2011-02-01

    An implantable prosthesis that stimulates vestibular nerve branches to restore sensation of head rotation and vision-stabilizing reflexes could benefit individuals disabled by bilateral loss of vestibular (inner ear balance) function. We developed a prosthesis that partly restores normal function in animals by delivering pulse frequency modulated (PFM) biphasic current pulses via electrodes implanted in semicircular canals. Because the optimal stimulus encoding strategy is not yet known, we investigated effects of varying biphasic current pulse frequency, amplitude, duration, and interphase gap on vestibulo-ocular reflex (VOR) eye movements in chinchillas. Increasing pulse frequency increased response amplitude while maintaining a relatively constant axis of rotation. Increasing pulse amplitude (range 0- 325 μA) also increased response amplitude but spuriously shifted eye movement axis, probably due to current spread beyond the target nerve. Shorter pulse durations (range 28- 340 μs) required less charge to elicit a given response amplitude and caused less axis shift than longer durations. Varying interphase gap (range 25- 175 μs) had no significant effect. While specific values reported herein depend on microanatomy and electrode location in each case, we conclude that PFM with short duration biphasic pulses should form the foundation for further optimization of stimulus encoding strategies for vestibular prostheses intended to restore sensation of head rotation.

  6. Laser impulse coupling measurements at 400 fs and 80 ps using the LULI facility at 1057 nm wavelength

    Science.gov (United States)

    Phipps, C. R.; Boustie, M.; Chevalier, J.-M.; Baton, S.; Brambrink, E.; Berthe, L.; Schneider, M.; Videau, L.; Boyer, S. A. E.; Scharring, S.

    2017-11-01

    At the École Polytechnique « LULI » facility, we have measured the impulse coupling coefficient Cm (target momentum per joule of incident laser light) with several target materials in vacuum, at 1057 nm and 400 fs and 80 ps pulse duration. A total of 64 laser shots were completed in a two-week experimental campaign, divided between the two pulse durations and among the materials. Our main purpose was to resolve wide discrepancies among reported values for Cm in the 100 ps region, where many applications exist. A secondary purpose was to compare Cm at 400 fs and 80 ps pulse duration. The 80 ps pulse was obtained by partial compression. Materials were Al, Ta, W, Au, and POM (polyoxymethylene, trade name Delrin). One application of these results is to pulsed laser ablation propulsion in space, including space debris re-entry, where narrow ranges in Cm and specific impulse Isp spell the difference between dramatic and uneconomical performance. We had difficulty measuring mass loss from single shots. Imparted momentum in single laser shots was determined using pendulum deflection and photonic Doppler velocimetry. Cm was smaller at the 400 fs pulse duration than at 80 ps. To our surprise, Cm for Al at 80 ps was at most 30 N/MW with 30 kJ/m2 incident fluence. On the other extreme, polyoxymethylene (POM, trade name Delrin) demonstrated 770 N/MW under these conditions. Together, these results offer the possibility of designing a Cm value suited to an application, by mixing the materials appropriately.

  7. Histological and molecular analysis of the long-pulse 1,064-nm Nd:YAG laser irradiation on the ultraviolet-damaged skin of hairless mice: In association with pulse duration change.

    Science.gov (United States)

    Rhee, Do Young; Cho, Hong Il; Park, Gyeong-Hun; Moon, Hye-Rim; Chang, Sung Eun; Won, Chong Hyun; Jung, Joon Min; Park, Ki-Young; Lee, Mi Woo; Choi, Jee Ho; Moon, Kee Chan; Lee, Deug-Chan; Goo, Boncheol

    2016-01-01

    Nonablative lasers have been widely used to improve photodamaged skin, although the mechanism underlying dermal collagen remodeling remains unclear. To investigate the effects and the molecular mechanisms of long-pulse neodymium-doped yttrium aluminum garnet (Nd:YAG) laser irradiation on dermal collagen remodeling in association with different pulse durations. Five hairless mice were pretreated with ultraviolet B irradiation for 8 weeks. The dorsal quadrant of each mouse was then irradiated twice at 1-week intervals at a pulse duration of 1 ms, 12 ms, or 50 ms, and a constant fluence of 20 J/cm(2). The levels of dermal collagen, mRNAs of procollagens, matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinases (TIMPs), and various growth factors were analyzed after 4 weeks. Long-pulse Nd:YAG treatment increased the dermal collagen level. A substantial increase in the level of procollagens, MMPs, TIMPs, and various growth factors was also observed irrespective of pulse duration, with a trend toward maximal increase at a pulse duration of 12 ms. Long-pulse 1,064-nm Nd:YAG laser irradiation promotes wound-healing process, which is characterized by the induction of growth factor expression and subsequent increase in MMPs and TIMPs, followed by matrix remodeling as confirmed by new procollagen production.

  8. Optical and electrical properties of SnO2 thin films after ultra-short pulsed laser annealing

    NARCIS (Netherlands)

    Scorticati, D.; Illiberi, A.; Römer, G.R.B.E.; Bor, T.; Ogieglo, W.; Klein Gunnewiek, M.; Lenferink, A.; Otto, C.; Skolski, J.Z.P.; Grob, F.; Lange, D.F. de; Huis in 't Veld, A.J.

    2013-01-01

    Ultra-short pulsed laser sources, with pulse durations in the ps and fs regime, are commonly exploited for cold ablation. However, operating ultra-short pulsed laser sources at fluence levels well below the ablation threshold allows for fast and selective thermal processing. The latter is especially

  9. Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration.

    Science.gov (United States)

    Lee, Ho; Alt, Clemens; Pitsillides, Costas M; Lin, Charles P

    2007-01-01

    Selective laser targeting of the retinal pigment epithelium (RPE) is an attractive method for treating RPE-associated disorders. We are developing a method for optically detecting intracellular microcavitation that can potentially serve as an immediate feedback of the treatment outcome. Thermal denaturation or intracellular cavitation can kill RPE cells during selective targeting. We examined the cell damage mechanism for laser pulse durations from 1 to 40 micros ex vivo. Intracellular cavitation was detected as a transient increase in the backscattered treatment beam. Cavitation and cell death were correlated for individual cells after single-pulse irradiation. The threshold radiant exposures for cell death (ED(50,d)) and cavitation (ED(50,c)) increased with pulse duration and were approximately equal for pulses of up to 10 micros. For 20 micros, the ED(50,d) was about 10% lower than the ED(50,c); the difference increased with 40-micros pulses. Cells were killed predominantly by cavitation (up to 10-micros pulses); probability of thermally induced cell death without cavitation gradually increases with pulse duration. Threshold measurements are discussed by modeling the temperature distribution around laser-heated melanosomes and the scattering function from the resulting cavitation. Detection of intracellular cavitation is a highly sensitive method that can potentially provide real-time assessment of RPE damage during selective laser targeting.

  10. Multi-wavelength picosecond BaWO4 Raman laser with long and short Raman shifts and 12-fold pulse shortening down to 3 ps at 1227 nm

    Science.gov (United States)

    Frank, M.; Jelínek, M., Jr.; Vyhlídal, D.; Kubeček, V.; Ivleva, L. I.; Zverev, P. G.; Smetanin, S. N.

    2018-02-01

    In this paper, we demonstrate the generation of three (1179, 1227, and 1323 nm) Stokes components of stimulated Raman scattering with long (925 cm-1 ) and short (332 cm-1 ) Raman shifts in an all-solid-state, synchronously pumped, extra-cavity Raman laser based on a BaWO4 crystal excited by a quasi-continuous, 36 ps, diode side-pumped Nd:GdVO4 laser generating at the wavelength of 1063 nm. We achieved the strongest 12-fold pulse shortening down to 3 ps at the 925 cm-1   +  332 cm-1 shifted 1227 nm wavelength due to a shorter dephasing time (wider linewidth) of the short-shift 332 cm-1 Raman line, resulting in a peak power of 2.5 kW.

  11. Effects of Thickness, Pulse Duration, and Size of Strip Electrode on Ferroelectric Electron Emission of Lead Zirconate Titanate Films

    Science.gov (United States)

    Yaseen, Muhammad; Ren, Wei; Chen, Xiaofeng; Feng, Yujun; Shi, Peng; Wu, Xiaoqing

    2017-11-01

    Sol-gel-derived lead zirconate titanate (PZT) thin-film emitters with thickness up to 9.8 μm have been prepared on Pt/TiO2/SiO2/Si wafer via chemical solution deposition with/without polyvinylpyrrolidone (PVP) modification, and the relationship between the film thickness and electron emission investigated. Notable electron emission was observed on application of a trigger voltage of 120 V for PZT film with thickness of 1.1 μm. Increasing the film thickness decreased the threshold field to initiate electron emission for non-PVP-modified films. In contrast, the electron emission behavior of PVP-modified films did not show significant dependence on film thickness, probably due to their porous structure. The emission current increased with decreasing strip width and space between strips. Furthermore, it was observed that increasing the duration of the applied pulse increased the magnitude of the emission current. The stray field on the PZT film thickness was also calculated and found to increase with increasing ferroelectric sample thickness. The PZT emitters were found to be fatigue free up to 105 emission cycles. Saturated emission current of around 25 mA to 30 mA was achieved for the electrode pattern used in this work.

  12. The influence of laser pulse duration and energy on ICP-MS signal intensity, elemental fractionation, and particle size distribution in NIR fs-LA-ICP-MS.

    Science.gov (United States)

    Diwakar, Prasoon K; Harilal, Sivanandan S; LaHaye, Nicole L; Hassanein, Ahmed; Kulkarni, Pramod

    Laser parameters, typically wavelength, pulse width, irradiance, repetition rate, and pulse energy, are critical parameters which influence the laser ablation process and thereby influence the LA-ICP-MS signal. In recent times, femtosecond laser ablation has gained popularity owing to the reduction in fractionation related issues and improved analytical performance which can provide matrix-independent sampling. The advantage offered by fs-LA is due to shorter pulse duration of the laser as compared to the phonon relaxation time and heat diffusion time. Hence the thermal effects are minimized in fs-LA. Recently, fs-LA-ICP-MS demonstrated improved analytical performance as compared to ns-LA-ICP-MS, but detailed mechanisms and processes are still not clearly understood. Improvement of fs-LA-ICP-MS over ns-LA-ICP-MS elucidates the importance of laser pulse duration and related effects on the ablation process. In this study, we have investigated the influence of laser pulse width (40 fs to 0.3 ns) and energy on LA-ICP-MS signal intensity and repeatability using a brass sample. Experiments were performed in single spot ablation mode as well as rastering ablation mode to monitor the Cu/Zn ratio. The recorded ICP-MS signal was correlated with total particle counts generated during laser ablation as well as particle size distribution. Our results show the importance of pulse width effects in the fs regime that becomes more pronounced when moving from femtosecond to picosecond and nanosecond regimes.

  13. Communication: Demonstration of a 20 ps X-ray switch based on a photoacoustic transducer

    Directory of Open Access Journals (Sweden)

    A. Jarnac

    2017-09-01

    Full Text Available We have studied an X-ray switch based on a gold coated indium antimonide crystal using time-resolved X-ray diffraction and demonstrated that the switch could reduce the pulse duration of a 100 ps X-ray pulse down to 20 ps with a peak reflectivity of 8%. We have used a dynamical diffraction code to predict the performance of the switch, which was then confirmed experimentally. The experiment was carried out at the FemtoMAX beamline at the short-pulse facility of the MAX IV laboratory. The performance and limitation of the switch are discussed in terms of acoustic transport properties between the two materials and the electron transport properties of gold.

  14. A chopper system for shortening the duration of pulsed supersonic beams seeded with NO or Br{sub 2} down to 13 μs

    Energy Technology Data Exchange (ETDEWEB)

    Lam, Jessica; Rennick, Christopher J.; Softley, Timothy P. [Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Rd, Oxford OX1 3TA (United Kingdom)

    2015-05-15

    A chopper wheel construct is used to shorten the duration of a molecular beam to 13 μs. Molecular beams seeded with NO or with Br{sub 2} and an initial pulse width of ≥200 μs were passed through a spinning chopper wheel, which was driven by a brushless DC in vacuo motor at a range of speeds, from 3000 rpm to 80 000 rpm. The resulting duration of the molecular-beam pulses measured at the laser detection volume ranged from 80 μs to 13 μs and was the same for both NO and Br{sub 2}. The duration is consistent with a simple analytical model, and the minimum pulse width measured is limited by the spreading of the beam between the chopper and the detection point as a consequence of the longitudinal velocity distribution of the beam. The setup adopted here effectively eliminates buildup of background gas without the use of a differential pumping stage, and a clean narrow pulse is obtained with low rotational temperature.

  15. Effect of applied voltage, duration and repetition frequency of RF pulses for pain relief on temperature spikes and electrical field: a computer modelling study.

    Science.gov (United States)

    Ewertowska, Elżbieta; Mercadal, Borja; Muñoz, Víctor; Ivorra, Antoni; Trujillo, Macarena; Berjano, Enrique

    2018-02-01

    The thermal and electrical effects of pulsed radiofrequency (PRF) for pain relief can be controlled by modifying the characteristics of the RF pulses applied. Our goal was to evaluate the influence of such modifications on the thermal and electric performance in tissue. A computational model was developed to compare the temperature and electric field time courses in tissue between a standard clinical protocol (45 V pulses, 20 ms duration, 2 Hz repetition frequency) and a new protocol (55 V pulses, 5 ms duration, 5 Hz repetition frequency) with a higher applied electric field but a smaller impact on temperature alterations in tissue. The effect of including a temperature controller was assessed. Complementarily, an agar-based experimental model was developed to validate the methodology employed in the computer modelling. The new protocol increased the electric field magnitude reached in the tissue by around +20%, without increasing the temperature. The temperature controller was found to be the fundamental factor in avoiding thermal damage to the tissue and reduced the total number of pulses delivered by around 67%. The experimental results matched moderately well with those obtained from a computer model built especially to mimic the experimental conditions. For the same delivered energy, the new protocol significantly increases the magnitude of the applied electric field, which may be the reason why it is clinically more effective in achieving pain relief.

  16. Ordered Arrays of Ferroelectric Nanoparticles by Pulsed Laser Deposition on PS-b-P4VP(PDP) Supramolecule-Based Templates

    NARCIS (Netherlands)

    van Zoelen, Wendy; Vlooswijk, Ard H. G.; Ferri, Anthony; Andringa, Anne-Marije; Noheda, Beatriz; ten Brinke, Gerrit

    2009-01-01

    Thin films of comb-shaped supramolecules have been used to create arrays of spatially separated ordered nanorods with a polystyrene core and a poly(4-vinyl pyridine) corona. Room temperature pulsed laser deposition of a uniform layer of lead titanate on top of these nanorod arrays and Subsequent

  17. Influence of consecutive picosecond pulses at 532 nm wavelength on laser ablation of human teeth

    Science.gov (United States)

    Mirdan, Balsam M.; Antonelli, Luca; Batani, Dimitri; Jafer, Rashida; Jakubowska, Katarzyna; Tarazi, Saad al; Villa, Anna Maria; Vodopivec, Bruno; Volpe, Luca

    2014-07-01

    The interaction of 40 ps pulse duration laser emitting at 532 nm wavelength with human dental tissue (enamel, dentin, and dentin-enamel junction) has been investigated. The crater profile and the surface morphology have been studied by using a confocal auto-fluorescence microscope (working in reflection mode) and a scanning electron microscope. Crater profile and crater morphology were studied after applying consecutive laser pulses and it was found that the ablation depth increases with the number of consecutive pulses, leaving the crater diameter unchanged. We found that the thermal damage is reduced by using short duration laser pulses, which implies an increased retention of restorative material. We observe carbonization of the irradiated samples, which does not imply changes in the chemical composition. Finally, the use of 40 ps pulse duration laser may become a state of art in conservative dentistry.

  18. Investigation of all-in-fiber Yb doped femtosecond fiber oscillator for generation of parabolic pulses in normal dispersion fiber amplifier

    Science.gov (United States)

    Frankinas, S.; Bartulevicius, T.; Michailovas, A.; Rusteika, N.

    2017-07-01

    In this work femtosecond passively mode-locked environmentally stable Ytterbium fiber oscillator generating pulses with duration of 380 fs is presented. Short pulse duration and smooth spectrum were obtained from the oscillator using chirped fiber Bragg grating with very low anomalous chromatic dispersion (0.15 ps2) and semiconductor saturable absorber mirror. Linearly chirped parabolic pulses were produced after amplification of the oscillator pulses in low concentration ytterbium doped fiber amplifier. Transform limited duration of the generated parabolic pulses was 110 fs.

  19. Impact of pulse duration in high power impulse magnetron sputtering on the low-temperature growth of wurtzite phase (Ti,Al)N films with high hardness

    Energy Technology Data Exchange (ETDEWEB)

    Shimizu, Tetsuhide, E-mail: simizu-tetuhide@tmu.ac.jp [Division of Human Mechatronics Systems, Graduate School of System Design, Tokyo Metropolitan University, 6-6, Asahigaoka, Hino-shi, 191-0065 Tokyo (Japan); Teranishi, Yoshikazu; Morikawa, Kazuo; Komiya, Hidetoshi; Watanabe, Tomotaro; Nagasaka, Hiroshi [Surface Finishing Technology Group, Tokyo Metropolitan Industrial Technology Research Institute, 2-4-10, Aomi, Kohtoh-ku, 135-0064 Tokyo (Japan); Yang, Ming [Division of Human Mechatronics Systems, Graduate School of System Design, Tokyo Metropolitan University, 6-6, Asahigaoka, Hino-shi, 191-0065 Tokyo (Japan)

    2015-04-30

    (Ti,Al)N films were deposited from a Ti{sub 0.33}Al{sub 0.67} alloy target with a high Al content at a substrate temperature of less than 150 °C using high power impulse magnetron sputtering (HIPIMS) plasma. The pulse duration was varied from 60 to 300 μs with a low frequency of 333 Hz to investigate the effects on the dynamic variation of the substrate temperature, microstructural grain growth and the resulting mechanical properties. The chemical composition, surface morphology and phase composition of the films were analyzed by energy dispersive spectroscopy, scanning electron microscopy and X-ray diffraction, respectively. Mechanical properties were additionally measured by using a nanoindentation tester. A shorter pulse duration resulted in a lower rate of increase in the substrate temperature with an exponentially higher peak target current. The obtained films had a high Al content of 70–73 at.% with a mixed highly (0002) textured wurtzite phase and a secondary phase of cubic (220) grains. Even with the wurtzite phase and the relatively high Al contents of more than 70 at.%, the films exhibited a high hardness of more than 30 GPa with a relatively smooth surface of less than 2 nm root-mean-square roughness. The hardest and smoothest surfaces were obtained for pulses with an intermediate duration of 150 μs. The differences between the obtained film properties under different pulse durations are discussed on the basis of the grain growth process observed by transmission electron microscopy. The feasibility of the low-temperature synthesis of AlN rich wurtzite phase (Ti,Al)N films with superior hardness by HIPIMS plasma duration was demonstrated. - Highlights: • Low temperature synthesis of AlN rich wurtzite phase (Ti,Al)N film was demonstrated. • 1 μm-thick TiAlN film was deposited under the temperature less than 150 °C by HIPIMS. • High Al content with highly (0002) textured wurtzite phase structure was obtained. • High hardness of 35 GPa were

  20. Effects of pulse duration and post-exposure period on the nitrite toxicity to a freshwater amphipod

    NARCIS (Netherlands)

    Alonso, A.; Camargo, J.A.

    2009-01-01

    This research assesses the effects of nitrite pulses and post-exposure periods after nitrite exposures on the survival of the freshwater amphipod Eulimnogammarus toletanus. A toxicity bioassay was performed using three different nitrite concentrations (0.5, 5.0 and 10.0 mg/L NO2-N), four pulse

  1. Electron pulse shaping in the FELIX RF accelerator

    NARCIS (Netherlands)

    Weits, H. H.; van der Geer, C. A. J.; Oepts, D.; van der Meer, A. F. G.

    1999-01-01

    The FELIX free-electron laser uses short pulses of relativistic electrons produced by an RF accelerator. The design target for the duration of these electron bunches was around 3 ps. In experiments we observed that the bunches emit coherently enhanced spontaneous emission (CSE) when they travel

  2. Optical design of the Short Pulse Soft X-ray Spectroscopy beamline at the Advanced Photon Source.

    Science.gov (United States)

    Reininger, R; Keavney, D J; Borland, M; Young, L

    2013-07-01

    The Short Pulse X-ray facility planned for the Advanced Photon Source (APS) upgrade will provide two sectors with photon beams having picosecond pulse duration. The Short Pulse Soft X-ray Spectroscopy (SPSXS) beamline will cover the 150-2000 eV energy range using an APS bending magnet. SPSXS is designed to take full advantage of this new timing capability in addition to providing circular polarized radiation. Since the correlation between time and electron momentum is in the vertical plane, the monochromator disperses in the horizontal plane. The beamline is designed to maximize flux and preserve the time resolution by minimizing the number of optical components. The optical design allows the pulse duration to be varied from 1.5 to 100 ps full width at half-maximum (FWHM) without affecting the energy resolution, and the resolution to be changed with minimal effect on the pulse duration. More than 10(9) photons s(-1) will reach the sample with a resolving power of 2000 and a pulse duration of ∼2 ps for photon energies between 150 and 1750 eV. The spot size expected at the sample position will vary with pulse duration and exit slit opening. At 900 eV and at a resolving power of 2000 the spot will be ∼10 µm × 10 µm with a pulse duration of 2.3 ps FWHM.

  3. Observation of enhanced field-free molecular alignment by two laser pulses

    DEFF Research Database (Denmark)

    Bisgaard, Christer; Poulsen, Mikael Dahlerup; Peronne, Emmanuel

    2004-01-01

    We show experimentally that field-free alignment of iodobenzene molecules, induced by a single, intense, linearly polarized 1.4-ps-long laser pulse, can be strongly enhanced by dividing the pulse into two optimally synchronized pulses of the same duration. For a given total energy of the two-puls......-pulse sequence the degree of alignment is maximized with an intensity ratio of 1:3 and by sending the second pulse near the time where the alignment created by the first pulse peaks....

  4. The influence of wavelength, temporal sequencing, and pulse duration on resonant infrared matrix-assisted laser processing of polymer films

    Science.gov (United States)

    O'Malley, S. M.; Schoeffling, Jonathan; Jimenez, Richard; Zinderman, Brian; Yi, SunYong; Bubb, D. M.

    2014-06-01

    We have carried out a systematic investigation of laser ablation plume interactions in resonant infrared matrix-assisted pulsed laser evaporation. The laser source utilized in this study was a mid-infrared OPO capable of dual sequential ns pulses with adjustable delay ranging from 1 to 100 μs. This unique capability enabled us both to probe the ablation plume with a second laser pulse, and to effectively double the laser fluence. The primary ablation target used for this study consisted of poly(methyl methacrylate) dissolved in a binary mixture of methanol and toluene. Both the critical thermodynamic and optical properties of the binary mixture were determined and used to interpret our results. We found that deposition rates associated with single pulse irradiation tracks with the optical absorption coefficient in the spectral range from 2,700 to 3,800 nm. In the case of dual sequential pulses, discrepancies in this trend have been linked to the rate of change in the optical absorption coefficient with temperature. The influence of fluence on deposition rate was found to follow a sigmoidal dependence. Surface roughness was observed to have a diametrically opposed trend with pulse delay depending on whether the OH or CH vibrational mode was excited. In the case of CH excitation, we suggest that the rougher films are due to the absorbance of the second pulse by droplets within the plume containing residual solvent which leads to the formation of molecular balloons and hence irregularly shaped features on the substrate.

  5. Source duration of stress and water-pressure induced seismicity derived from experimental analysis of P wave pulse width in granite

    Science.gov (United States)

    Masuda, K.

    2013-12-01

    Pulse widths of P waves in granite, measured in the laboratory, were analyzed to investigate source durations of rupture processes for water-pressure induced and stress-induced microseismicity. Much evidence suggests that fluids in the subsurface are intimately linked to faulting processes. Studies of seismicity induced by water injection are thus important for understanding the trigger mechanisms of earthquakes as well as for engineering applications such as hydraulic fracturing of rocks at depth for petroleum extraction. Determining the cause of seismic events is very important in seismology and engineering; however, water-pressure induced seismic events are difficult to distinguish from those induced by purely tectonic stress. To investigate this problem, we analyzed the waveforms of acoustic emissions (AEs) produced in the laboratory by both water-pressure induced and stress-induced microseismicity. We used a cylinder (50 mm in diameter and 100 mm in length) of medium-grained granite. We applied a differential stress of about 70% of fracture strength, to the rock sample under 40 MPa confining pressure and held it constant throughout the experiment. When the primary creep stage and acoustic emissions (AEs) caused by the initial loading had ceased, we injected distilled water into the bottom end of the sample at a constant pressure of 17 MPa until macroscopic fracture occurred. We analysed AE waveforms produced by stress-induced AEs which occurred before the water-injection and by water-pressure induced AEs which occurred after the water-injection. Pulse widths were measured from the waveform traces plotted from the digital data. To investigate the source duration of the rupture process, we estimated the pulse width at the source and normalized by event magnitude to obtain a scaled pulse width at the source. After the effects of event size and hypocentral distance were removed from observed pulse widths, the ratio of the scaled source durations of water

  6. Investigation of response of high-temperature superconducting Bi sub 2 Sr sub 2 CaCu sub 2 O sub y bolometer at hard substrate on infrared laser pulses of permanent power and variable relative pulse duration

    CERN Document Server

    Antonenko, S V; Korotkov, D P; Maltsev, S N

    2001-01-01

    A method for studying bolometric response of superconducting films to effect of a sequence of IR pulses of identical power and variable relative pulse duration using an optical rod was developed. A semiconductor laser was used as radiation source. Using the method suggested experiments on studying characteristics of a superconducting bolometer on the basis of Bi sub 2 Sr sub 2 CaCu sub 2 O sub y film on a MgO substrate were conducted. It was found that increase in pulse repetition frequency of IR laser in the range of 1-7 kHz brought about a decrease (by a factor of 2.5) of variable component of the bolometer response amplitude

  7. Free-electron-laser-induced shock-wave control and mechanistic analysis using pulse control.

    Science.gov (United States)

    Kanai, Taizo; Yoshihashi-Suzuki, Sachiko; Awazu, Kunio

    2008-11-01

    The wavelength of the free electron laser (FEL) in Osaka University can be continuously varied in the range of 5.0-20.0 microm. The FEL has a double-pulse structure, consisting of a train of macropulses of pulse duration 12 micros. Each macropulse contains a train of 330 micropulses of pulse duration 5 ps. The tunability and picosecond pulses afford new medical and biological applications. However, a macropulse of long pulse duration leads to undesirable secondary effects. Precise control of the macropulse duration is essential for the high-precision applications of the FEL. An FEL pulse control system using acousto-optic modulators has been developed to investigate mechanical (shock-wave) effects of the FEL on living tissues. With this system, we have controlled photoinduced shock waves and determine the mechanism of interaction during FEL-induced tissue ablation.

  8. Laser assisted removal of synthetic painting-conservation materials using UV radiation of ns and fs pulse duration: Morphological studies on model samples

    Energy Technology Data Exchange (ETDEWEB)

    Pouli, P., E-mail: ppouli@iesl.forth.gr [Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas (IESL-FORTH), P.O. Box 1385, Heraklion, 71110 Crete (Greece); Nevin, A. [Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas (IESL-FORTH), P.O. Box 1385, Heraklion, 71110 Crete (Greece); Courtauld Institute of Art, University of London, Somerset House, Strand, WC2R 0RN, London (United Kingdom); Andreotti, A.; Colombini, P. [Dipartimento di Chimica e Chimica Industriale, Universita di Pisa, via Risorgimento 35, 56126 Pisa (Italy); Georgiou, S. [Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas (IESL-FORTH), P.O. Box 1385, Heraklion, 71110 Crete (Greece); Fotakis, C. [Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas (IESL-FORTH), P.O. Box 1385, Heraklion, 71110 Crete (Greece); Department of Physics, University of Crete, P.O. Box 2208, Heraklion, 71003 (Greece)

    2009-02-15

    In an effort to establish the optimal parameters for the cleaning of complex layers of polymers (mainly based on acrylics, vinyls, epoxys known as Elvacite, Laropal, Paraloid B72, among others) applied during past conservation treatments on the surface of wall paintings, laser cleaning tests were performed with particular emphasis on the plausible morphological modifications induced in the remaining polymeric material. Pulse duration effects were studied using laser systems of different pulse durations (ns and fs) at 248 nm. Prior to tests on real fragments from the Monumental Cemetery in Pisa (Italy) which were coated with different polymers, attention was focused on the study of model samples consisting of analogous polymer films cast on quartz disks. Ultraviolet irradiation is strongly absorbed by the studied materials both in ns and fs irradiation regimes. However, it is demonstrated that ultrashort laser pulses result in reduced morphological alterations in comparison to ns irradiation. In addition, the dependence of the observed alterations on the chemical composition of the consolidation materials in both regimes was examined. Most importantly, it was shown that in this specific conservation problem, an optimum cleaning process may rely not only on the minimization of laser-induced morphological changes but also on the exploitation of the conditions that favour the disruption of the adhesion between the synthetic material and the painting.

  9. Precipitation extremes on multiple timescales - Bartlett-Lewis rectangular pulse model and intensity-duration-frequency curves

    Science.gov (United States)

    Ritschel, Christoph; Ulbrich, Uwe; Névir, Peter; Rust, Henning W.

    2017-12-01

    For several hydrological modelling tasks, precipitation time series with a high (i.e. sub-daily) resolution are indispensable. The data are, however, not always available, and thus model simulations are used to compensate. A canonical class of stochastic models for sub-daily precipitation are Poisson cluster processes, with the original Bartlett-Lewis (OBL) model as a prominent representative. The OBL model has been shown to well reproduce certain characteristics found in observations. Our focus is on intensity-duration-frequency (IDF) relationships, which are of particular interest in risk assessment. Based on a high-resolution precipitation time series (5 min) from Berlin-Dahlem, OBL model parameters are estimated and IDF curves are obtained on the one hand directly from the observations and on the other hand from OBL model simulations. Comparing the resulting IDF curves suggests that the OBL model is able to reproduce the main features of IDF statistics across several durations but cannot capture rare events (here an event with a return period larger than 1000 years on the hourly timescale). In this paper, IDF curves are estimated based on a parametric model for the duration dependence of the scale parameter in the generalized extreme value distribution; this allows us to obtain a consistent set of curves over all durations. We use the OBL model to investigate the validity of this approach based on simulated long time series.

  10. Transverse pump-probe microscopy of moving breakdown, filamentation and self-organized absorption in alkali aluminosilicate glass using ultrashort pulse laser

    OpenAIRE

    Grossmann, D.; Reininghaus, M.; Kalupka, C.; Kumkar, M.; Poprawe, R.

    2016-01-01

    We present time and space resolved transverse pump-probe measurements of the free electron and defect generation induced by nonlinear absorption of ultra short pulsed laser radiation in unhardened Corning Gorilla glass. The applied setup exhibits a 100 fs probe pulse duration and an independent pump pulse duration up to 5 ps. Hence, our work comprises the absorption of ultra short pulsed laser radiation at a wavelength of 800 nm and pulse energies from 10 μJ to 50 μJ up to a delay of 6 ns. Ou...

  11. Long-Duration Soft X-Ray Pulses by XeCl Laser Driven Plasmas and Applications.

    Science.gov (United States)

    Bollanti, S; Di Lazzaro, P; Flora, F; Giordano, G; Letardi, T; Schina, G; Zheng, C E; Filippi, L; Palladino, L; Reale, A; Taglieri, G; Batani, D; Mauri, A; Belli, M; Scafati, A; Reale, L; Albertano, P; Grilli, A; Faenov, A; Pikuz, T; Cotton, R

    1995-01-01

    We report the characterization of a soft x-ray plasma source generated by a long-pulse XeCl excimer laser system. The output energy is 4 J at a wavelength of 308 nm in a 100-ns pulse. The intensity of radiation on target is estimated to be 4 × 1012 W cm-2. X-ray emission spectra of the plasma have been recorded using a double focusing spatial resolution spectrometer with a spherical mica crystal. From these measurements, the plasma temperature and electron density have been estimated. Various applications of such a plasma source have been investigated. First images of whole intact living cells from our system, imaged using the technique of soft x-ray contact microscopy, utilizing x rays in the "water window" region (280-530 eV), are shown. The suitability of the source for other applications, for example, x-ray lithography and radiation damage studies, to living cells are discussed. Possible improvements to the x-ray source for the various applications are proposed.

  12. Microtensile bond strength of an etch-and-rinse adhesive to enamel and dentin after Er:YAG laser pretreatment with different pulse durations.

    Science.gov (United States)

    Firat, Esra; Gurgan, Sevil; Gutknecht, Norbert

    2012-01-01

    The purpose of this study is to evaluate microtensile bond strength (μTBS) of an etch-and-rinse adhesive to enamel and dentin after treatment with Er:YAG laser using different pulse durations. Extracted human molars were flattened to obtain enamel or dentin surfaces. The enamel specimens (E) were divided into nine groups and the dentin (D) specimens were divided into seven groups according to the surface treatments (n = 6). E-C: acid was applied according to the manufacturer's instructions and used as control, E-SSP: 120 mJ, 10 Hz, SSP (50 μs), E-SSP-A: 120 mJ,10 Hz, SSP+acid, E-VSP: 120 mJ, 10 Hz, VSP (100 μs), E-VSP-A: 120 mJ, 10 Hz, VSP+acid, E-SP: 120 mJ, 10 Hz, SP (150 μs), E-SP-A:120 mJ,10 Hz, SP+acid, E-LP:120 mJ,10 Hz, LP (300 μs), E-LP-A:120 mJ,10 Hz, LP+acid; D-C: acid was applied and used as control, D-SSP: 80 mJ, 10 Hz, SSP, D-SSP-A: 80 mJ, 10 Hz, SSP+acid, D-VSP: 80 mJ, 10 Hz, VSP, D-VSP-A: 80 mJ, 10 Hz, VSP+acid, D-SP: 80 mJ, 10 Hz, SP, D-SP-A: 80 mJ, 10 Hz, SP+acid. After application of etch-and-rinse adhesive, composite built-ups were created with a nanoceramic composite. Specimens were sectioned into serial 1-mm(2) sticks, and μTBS was measured in five sticks from each tooth randomly selected (n = 30). Failure modes were determined under a stereomicroscope. μTBS test data were analyzed by Welch-ANOVA followed by Dunnett's T3 tests and failure mode distributions were analyzed by Pearson Chi-square test (p = 0.05). μTBS was higher for enamel and dentin after additional acid etching than laser irradiation alone. E-SSP-A group exhibited the highest μTBS for enamel (p 0.05). The μTBS of laser-irradiated but not acid-etched groups decreased when longer pulse durations were used. Laser treatment could enhance or impair the μTBS to enamel and dentin depending on the pulse duration used and additional acid application.

  13. Motor-Generator powering the PS (Proton Synchrotron) main magnets

    CERN Multimedia

    1983-01-01

    This motor-generator,30 MW peak, 1500 r.p.m.,pulsed power supply for the PS main magnet replaced in 1968 the initial 3000 r.p.m. motor-generator-flywheel set which had served from the PS start-up in 1959 until end 1967. See also photo 8302337 and its abstract.

  14. Removal of Verrucaria nigrescens from Carrara marble artefacts using Nd:YAG lasers: comparison among different pulse durations and wavelengths

    Science.gov (United States)

    Osticioli, I.; Mascalchi, M.; Pinna, D.; Siano, S.

    2015-03-01

    The periodical removal of biodeteriogens is a fundamental need for the preservation of outdoor stone cultural heritage, which is stimulating significant efforts toward the development of low-impact conservation strategies. In the present work, the potential of laser removal of Verrucaria nigrescens Pers. from Carrara marble and the evaluation of the associated biocide effect on the organism residues embedded in the surface texture and through the outer porosities of the stone substrate were investigated. The fundamental wavelength of Nd:YAG laser (1,064 nm), commonly used in stone cleaning, and its second harmonic (532 nm) were comparatively tested. The phenomenology of laser treatments carried out in different irradiation conditions was characterized using optical, epifluorescence, and electron microscopes along with chlorophyll fluorescence with pulsed amplitude-modulated imaging. The results achieved show that 532 nm can provide significant advantages with respect to 1,064 nm. The potential of the latter against the biodeteriogens appears rather limited because of the low optical absorption, whereas the former can allow effective and practicable laser treatments, which disclose a significant application perspective.

  15. An exhaustive study of laser damage in ion beam sputtered pure and mixture oxide thin films at 1030 nm with 500 fs pulse durations

    Science.gov (United States)

    Gallais, Laurent; Mangote, Benoit; Commandré, Mireille; Mende, Mathias; Jensen, Lars; Ehlers, Henrik; Jupé, Marco; Ristau, Detlev; Melninkaitis, Andrius; Sirutkaitis, Valdas; Kičas, Simonas; Tolenis, Tomas; Drazdys, Ramutis

    2012-11-01

    We report on the laser damage resistance of thin films prepared by Ion Beam Sputtering. The samples are fused silica substrates coated with single layer films of pure oxides (SiO2, Nb2O5, ZrO2, HfO2, Ta2O5, Al2O3, Sc2O3) and oxide mixtures with various ratios (Nb2O5/SiO2, ZrO2/SiO2, HfO2/SiO2, Ta2O5/SiO2, Al2O3/SiO2 and Sc2O3/SiO2). For this study the LIDT of more than 60 different samples have measured at 1030nm with pulse durations of 500fs with single pulse irradiation. The results are expressed and compared in terms of LIDT as a function of the measured band gap energy and refractive index. For simple oxide materials a linear evolution of the LIDT with bandgap is observed, with the exception of Sc2O3 material where a very high damage threshold is observed, compared to other high index materials. In the case of mixtures, a more complex behavior is evidenced.

  16. Last PS magnet refurbished

    CERN Document Server

    2009-01-01

    PS Magnet Refurbishment Programme Completed. The 51st and final refurbished magnet was transported to the PS on Tuesday 3 February. The repair and consolidation work on the PS started back in 2003 when two magnets and a busbar connection were found to be faulty during routine high-voltage tests. The cause of the fault was a combination of age and radiation on electrical insulation. After further investigation the decision was taken to overhaul half of the PS’s 100 magnets to reduce the risk of a similar fault. As from 20 February the PS ring will start a five-week test programme to be ready for operation at the end of March.

  17. Numerical study of fourth-harmonic generation of a picosecond laser pulse with time predelay

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, T.; Kato, Y.; Daido, H. [Institute of Laser Engineering, Osaka University, Yamada-oka 2-6, Suita, Osaka 565 (Japan)

    1996-06-01

    We describe fourth-harmonic generation of a picosecond laser pulse with KDP crystals. The coupled nonlinear equations for the parametric process including the third-order nonlinear susceptibility have been solved. Applying a time predelay in the doubling crystal between the extraordinary and the ordinary waves of the fundamental pulse causes the group-velocity mismatch and the nonlinear phase shift in the doubling crystal to be compensated for each other, resulting in pulse duration compression at the fourth-harmonic wavelength. It is shown that the reduction from a 1-ps fundamental pulse to a 0.25-ps fourth-harmonic pulse can be achieved at an incident intensity of 50 GW/cm{sup 2}. {copyright} {ital 1996 Optical Society of America.}

  18. Generation of 25-TW Femtosecond Laser Pulses at 515 nm with Extremely High Temporal Contrast

    Directory of Open Access Journals (Sweden)

    Marco Hornung

    2015-12-01

    Full Text Available We report on the frequency doubling of femtosecond laser pulses at 1030 nm center wavelength generated from the fully diode-pumped laser system POLARIS. The newly generated pulses at a center wavelength of 515 nm have a pulse energy of 3 J with a pulse duration of 120 fs. On the basis of initially ultra-high contrast seed pulses we expect a temporal intensity contrast better 10 17 200 ps before the peak of the main pulse. We analyzed the temporal intensity contrast from milliseconds to femtoseconds with a dynamic range covering more than 20 orders of magnitude. The pulses were focussed with a f/2-focussing parabola resulting in a peak intensity exceeding 10 20 W / cm 2 . The peak power and intensity are to the best of our knowledge the highest values for 515 nm-laser-pulses achieved so far.

  19. Colliding pulse mode-locked VECSEL

    Science.gov (United States)

    Marah, Declan; Laurain, Alexandre; Stolz, Wolfgang; Koch, Stephan; Ruiz Perez, Antje; McInerney, John; Moloney, Jerome

    2016-03-01

    Recent development of high power femtosecond pulse modelocked VECSEL with gigahertz pulse repetition rates sparked an increased interest from the scientific community due to the broad field of applications for such sources, such as frequency metrology, high-speed optical communication systems or high-resolution optical sampling. To the best of our knowledge, we report for the first time a colliding pulse modelocked VECSEL, where the VECSEL gain medium and a semiconductor saturable absorber (SESAM) are placed inside a ring cavity. This cavity geometry provides both a practical and an efficient way to get optimum performance from a modelocked laser system. The two counter propagating pulses in our ring cavity synchronize in the SESAM because the minimum energy is lost when they saturate the absorber together. This stronger saturation of the absorber increases the stability of the modelocking and reduces the overall losses of the laser for a given intra-cavity fluence, leading to a lower modelocking threshold. This also allows the generation of fundamental modelocking at a relatively low repetition rate (pulse repetition rate of 1GHz and a pulse duration ranging from 1ps to 3ps. The emitted spectrum was centered at 1007nm with a FWHM of 3.1nm, suggesting that shorter pulses can be obtained with adequate dispersion compensation. The laser characteristics such as the pulse duration and stability are studied in detail.

  20. Effect of burst frequency and duration of kilohertz-frequency alternating currents and of low-frequency pulsed currents on strength of contraction, muscle fatigue, and perceived discomfort.

    Science.gov (United States)

    Laufer, Yocheved; Elboim, Michal

    2008-10-01

    Low-frequency pulsed currents (LPCs) and kilohertz-frequency alternating currents (KACs) are used clinically to augment muscle contractions. Treatment effectiveness may be enhanced by selecting stimulation parameters that evoke the strongest contractions with minimal discomfort and fatigue. The objective of this study was to compare maximally induced strength (force-producing capacity) of contractions, muscle fatigue, and discomfort associated with an LPC and with 3 KACs differing in frequency and duration of burst modulation. This was a repeated-measures trial, with randomized order of current presentation. The study was conducted in the physical therapy laboratory at the University of Haifa. Twenty-six volunteers without impairments, with a mean age of 27.4 years (SD=5.0, range=21-45), participated. All currents were applied in separate sessions to the wrist extensors of each subject. Currents consisted of an LPC with a 50-Hz pulse frequency and 3 KACs with a 2.5-kHz carrier frequency, including the "Russian current" (RC) burst modulated at 50 Hz with 25 cycles per burst and 2 currents burst modulated at 20 or 50 Hz with 10 cycles per burst. The maximal electrically induced isometric force, the force integral of 21 electrically induced consecutive contractions, and the degree of discomfort were recorded. Force of contraction was not affected by type of current. The LPC was least fatiguing, and the RC was most fatiguing, with the 2 other KACs having an intermediate effect. Degree of discomfort was higher with the KAC modulated at 20 Hz. When comfort, strength, and fatigue are considered jointly, the LPC is advantageous. Electrically induced fatigue is affected by the number of cycles per second, rather than the number of bursts per second.

  1. A large shock vein in L chondrite Roosevelt County 106: Evidence for a long-duration shock pulse on the L chondrite parent body

    Science.gov (United States)

    Sharp, Thomas G.; Xie, Zhidong; de Carli, Paul S.; Hu, Jinping

    2015-11-01

    A large shock-induced melt vein in L6 ordinary chondrite Roosevelt County 106 contains abundant high-pressure minerals, including olivine, enstatite, and plagioclase fragments that have been transformed to polycrystalline ringwoodite, majorite, lingunite, and jadeite. The host chondrite at the melt-vein margins contains olivines that are partially transformed to ringwoodite. The quenched silicate melt in the shock veins consists of majoritic garnets, up to 25 μm in size, magnetite, maghemite, and phyllosilicates. The magnetite, maghemite, and phyllosilicates are the terrestrial alteration products of magnesiowüstite and quenched glass. This assemblage indicates crystallization of the silicate melt at approximately 20-25 GPa and 2000 °C. Coarse majorite garnets in the centers of shock veins grade into increasingly finer grained dendritic garnets toward the vein margins, indicating increasing quench rates toward the margins as a result of thermal conduction to the surrounding chondrite host. Nanocrystalline boundary zones, that contain wadsleyite, ringwoodite, majorite, and magnesiowüstite, occur along shock-vein margins. These zones represent rapid quench of a boundary melt that contains less metal-sulfide than the bulk shock vein. One-dimensional finite element heat-flow calculations were performed to estimate a quench time of 750-1900 ms for a 1.6-mm thick shock vein. Because the vein crystallized as a single high-pressure assemblage, the shock pulse duration was at least as long as the quench time and therefore the sample remained at 20-25 GPa for at least 750 ms. This relatively long shock pulse, combined with a modest shock pressure, implies that this sample came from deep in the L chondrite parent body during a collision with a large impacting body, such as the impact event that disrupted the L chondrite parent body 470 Myr ago.

  2. Inside the PS tunnel

    CERN Multimedia

    1974-01-01

    Pre-start work is going on at the end of the PS long shut-down. The photo shows secondary beams drawn from an internal target (bottom) towards South Hall, behind the shielding wall (top) (see also photo 7409012X).

  3. PS Control Room

    CERN Multimedia

    CERN PhotoLab

    1963-01-01

    The good old PS Control Room, all manual. For each parameter, a knob or a button to control it; for each, a light or meter or oscilloscope to monitor it; carefully written pages serve as the data bank; phones and intercom for communication. D.Dekkers is at the microphone, M.Valvini sits in front.

  4. PS auxiliary magnet

    CERN Multimedia

    CERN PhotoLab

    1974-01-01

    Units of the PS auxiliary magnet system. The picture shows how the new dipoles, used for vertical and horizontal high-energy beam manipulation, are split for installation and removal so that it is not necessary to break the accelerator vacuum. On the right, adjacent to the sector valve and the windings of the main magnet, is an octupole of the set.

  5. Experimental observation of superluminal pulse reflection in a double-Lorentzian photonic band gap.

    Science.gov (United States)

    Longhi, S; Marano, M; Laporta, P; Belmonte, M; Crespi, P

    2002-04-01

    We report on the experimental observation of superluminal reflection of picosecond optical pulses at 1.5 microm using a specially designed 30-cm-long fiber Bragg grating (FBG) that realizes a spectral reflectivity profile given by the superposition of two closely spaced Lorentzian lines. Probing pulses of 380 ps duration tuned midway between the two Lorentzian lines are reflected without appreciable distortion with a measured peak pulse advancement of approximately 60 ps. The achievement of the negative group delay is due to the interference of the two resonance modes of the FBG structure and has a close connection to the phenomenon of negative group velocity for pulse propagation in an inverted medium possessing a doublet line.

  6. Demonstration of Two-Atom Entanglement with Ultrafast Optical Pulses

    Science.gov (United States)

    Wong-Campos, J. D.; Moses, S. A.; Johnson, K. G.; Monroe, C.

    2017-12-01

    We demonstrate quantum entanglement of two trapped atomic ion qubits using a sequence of ultrafast laser pulses. Unlike previous demonstrations of entanglement mediated by the Coulomb interaction, this scheme does not require confinement to the Lamb-Dicke regime and can be less sensitive to ambient noise due to its speed. To elucidate the physics of an ultrafast phase gate, we generate a high entanglement rate using just ten pulses, each of ˜20 ps duration, and demonstrate an entangled Bell state with (76 ±1 )% fidelity. These results pave the way for entanglement operations within a large collection of qubits by exciting only local modes of motion.

  7. PS injection area

    CERN Multimedia

    1974-01-01

    Looking against the direction of protons in the main ring (left): the beam coming from the linac 1 either goes to the booster (on the right) or is deflected towards the PS to be directly injected into section 26 (facing the camera). Also shown the start of the TT2 line, ejected from straight section 16 to go towards the ISR passing over the beam line from the linac. (see Photo Archive 7409009)

  8. PS injection area

    CERN Multimedia

    1974-01-01

    To the right is the PS ring viewed along the direction of the protons. At the left the injection line coming from the 50 MeV Linac 1 (bottom) and going towards the 800 MeV booster, or deflected to the right to be injected directly into straight section 16. The drumlike element behind the (blue) dipole magnet is a 'debuncher' (a 200 MHz cavity). See photos 7409014X and 7409009.

  9. A novel-type tunable and narrowband extreme ultraviolet radiation source based on high-harmonic conversion of picosecond laser pulses

    NARCIS (Netherlands)

    Barkauskas, M.; Brandi, F.; Giammanco, F.; Neshev, D.; Pirri, A.; Ubachs, W.M.G.

    2005-01-01

    At the Laser Centre Vrije Universiteit a table-top size, tunable and narrowband laser-based source of extreme ultraviolet radiation was developed using high-harmonic generation of powerful laser pulses of 300 ps duration and Fourier-transform limited bandwidth. The generated radiation has

  10. Motor-generator set of the PS main supply

    CERN Multimedia

    Photographic Service; CERN PhotoLab

    1968-01-01

    Already in 1964, the PS improvement programme included a new main magnet supply with more power for the longer cycles needed for slow extraction at the full energy of 26 GeV. This motor-generator set was installed in 1967 and took up service at the beginning of 1968. Regularly serviced and fitted with modern electronic regulation, it pulses the PS to this day.

  11. Free Electron Laser Pulse Control by Acousto Optic Modulators

    CERN Document Server

    Kanai, T; Yoshihashi-Suzuki, S

    2005-01-01

    Free Electron Laser (FEL) at Osaka University can be continuously varied in the range of 5.0-20.0 μm. A FEL has a double pulse structure. The structure consists of a train of macropulses of the pulse width 15 μs, and each macropulse contains a train of 330 micropulses of the pulse width 5 ps. The tunability and short pulse afford new medical applications such as investigation of protein dynamics and ablation of soft tissues. Precise control of micropulse train is very important for medical applications using FEL because macropulse with long pulse duration sometimes leads to undesirable thermal effects. FEL pulse control system using an acousto optic modulators (AOM) was developed in order to investigate of non-thermal effect between the FEL and tissue. This system provide a very good efficiency (~60 %) and a fast switching speed (>200 ns). A phosphorylated protein was irradiated with FEL that controlled the pulse. These result confirmed that the thermal effect is controlled by pulse durat...

  12. At PS170 (APPLE)

    CERN Multimedia

    CERN PhotoLab

    1983-01-01

    APPLE stands for Antiproton-Proton to Pair of LEptons (an acronym of the ancestor experiment PAPLEP), the PS170 experiment setup at LEAR to study e+e-pair production in antiproton-proton annihilation by Padova-(CEN) Saclay- Torino Collaboration. It consisted of a liquid hydrogen target surrounded by several layers of proportional chambers in the vertical field of a C-magnet (this photo), a gas Cerenkov counter, wire chambers, hodoscopes, and an electromagnetic calorimeter (see photo 8302539X, 8302540X). See also photo 8301539X for the setup assembly at an early stage.

  13. The Septa for LEIR Extraction and PS Injection

    CERN Document Server

    Borburgh, J; Masson, T; Prost, A

    2006-01-01

    The Low Energy Ion Ring (LEIR) is part of the CERN LHC injector chain for ions. The LEIR extraction uses a pulsed magnetic septum, clamped around a metallic vacuum chamber. Apart from separating the ultra high vacuum in the LEIR ring from the less good vacuum in the transfer line to the PS this chamber also serves as magnetic screen and retains the septum conductor in place. The PS ion injection septum consists of a pulsed laminated magnet under vacuum, featuring a single-turn water cooled coil and a remote positioning system. The design, the construction and the commissioning of both septa are described.

  14. PS wire chamber

    CERN Multimedia

    1970-01-01

    A wire chamber used at CERN's Proton Synchrotron accelerator in the 1970s. Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  15. Beyond iPS!

    Directory of Open Access Journals (Sweden)

    Editorial

    2012-01-01

    Full Text Available It’s undoubtedly a jubilant moment for scientists and clinicians working in the stem cell arena as Prof. Gurdon and Prof. Shinya Yamanaka have been chosen for the Nobel Prize in Physiology & Medicine this year. The mystery of cell biology is something unfathomable and probably the work of this duo as well as the other scientists, who have put their hands on in- vitro de-differentiation have opened our eyes to a new window or a new paradigm in cell biology. The iPS invention has brought a lot of hope in terms of potential direct benefits to treat several diseases, which have no definite options at the moment. But, we envisage that several spin-offs could come out of this invention and one very significant spin-off finding recently witnessed is the finding by Prof. Masaharu Seno and his team of researchers at the Okayama University, Japan (Chen L, et al. 2012, PLoS ONE 7(4:e33544.doi:10.1371/journal.pone.0033544. According to Prof. Seno, mouse iPS cells (miPS when cultured in the conditioned medium derived from cancer cell lines, differentiate into cancer stem cells (CSCs. While differentiating into CSCs, they do retain the potential to develop endothelial progenitor cells. Several questions arise here: 1.Are these miPS derived CSCs really pluripotent, even if the terminal differentiation destined to specific phenotypes? 2.Shouldn’t the Cancer Stem Cells be termed as cancer progenitor cells, as till date they are considered to be producing only cancer cells but not pluripotent to yield other types of normal tissues? The spin-offs could be infinite as the process of differentiation and de-differentiation happening due to trillions of signals and pathways, most still remaining not-so-well understood. A special mention should be made to Prof. Shinya Yamanaka as he has several sterling qualities to be a role-model for budding scientists. Apart from his passion for science, which made him shift his career from orthopedics to a cell biologist, his

  16. Pulse dynamics in carbon nanotube mode-locked fiber lasers near zero cavity dispersion.

    Science.gov (United States)

    Wang, Jinzhang; Cai, Zhiping; Xu, Ping; Du, Geguo; Wang, Fengqiu; Ruan, Shuangchen; Sun, Zhipei; Hasan, Tawfique

    2015-04-20

    We numerically and experimentally analyze the output characteristics and pulse dynamics of carbon nanotube mode-locked fiber lasers near zero cavity dispersion (from 0.02 to ~-0.02 ps(2)). We focus on such near zero dispersion cavities to reveal the dispersion related transition between different mode-locking regimes (such as soliton-like, stretched-pulse and self-similar regimes). Using our proposed model, we develop a nanotube-mode-locked fiber laser setup generating ~97 fs pulse which operates in the stretched-pulse regime. The corresponding experimental results and pulse dynamics are in good agreement with the numerical results. Also, the experimental results from soliton-like and self-similar regimes exhibit the same trends with simulations. Our study will aid design of different mode-locking regimes based on other new saturable absorber materials to achieve ultra-short pulse duration.

  17. Broadband mid-infrared pulses from potassium titanyl arsenate/zinc germanium phosphate optical parametric amplifier pumped by Tm, Ho-fiber-seeded Ho:YAG chirped-pulse amplifier.

    Science.gov (United States)

    Malevich, Pavel; Kanai, Tsuneto; Hoogland, Heinar; Holzwarth, Ronald; Baltuška, Andrius; Pugžlys, Audrius

    2016-03-01

    We present a concept of a white-light-seeded-cascaded mid-infrared (mid-IR) optical parametric amplifier (OPA) based on potassium titanyl arsenate and zinc germanium phosphate nonlinear optical crystals and producing 100-μJ level pulses centered at 5300 nm, with the spectrum supporting four-optical-cycle pulse duration. The OPA is pumped by 2090-nm master oscillator/power amplifier based on a Tm,Ho-fiber laser seeder and a Ho:YAG regenerative amplifier delivering 3.8-mJ sub-ps pulses at a repetition rate of 1 kHz. We validate that output parameters of the OPA are scalable by means of increasing the pulse energy, decreasing the pulse duration and redshifting the central wavelength.

  18. Generation of short electrical pulses based on bipolar transistorsny

    Directory of Open Access Journals (Sweden)

    M. Gerding

    2004-01-01

    Full Text Available A system for the generation of short electrical pulses based on the minority carrier charge storage and the step recovery effect of bipolar transistors is presented. Electrical pulses of about 90 ps up to 800 ps duration are generated with a maximum amplitude of approximately 7V at 50Ω. The bipolar transistor is driven into saturation and the base-collector and base-emitter junctions become forward biased. The resulting fast switch-off edge of the transistor’s output signal is the basis for the pulse generation. The fast switching of the transistor occurs as a result of the minority carriers that have been injected and stored across the base-collector junction under forward bias conditions. If the saturated transistor is suddenly reverse biased the pn-junction will appear as a low impedance until the stored charge is depleted. Then the impedance will suddenly increase to its normal high value and the flow of current through the junction will turn to zero, abruptly. A differentiation of the output signal of the transistor results in two short pulses with opposite polarities. The differentiating circuit is implemented by a transmission line network, which mainly acts as a high pass filter. Both the transistor technology (pnp or npn and the phase of the transfer function of the differentating circuit influence the polarity of the output pulses. The pulse duration depends on the transistor parameters as well as on the transfer function of the pulse shaping network. This way of generating short electrical pulses is a new alternative for conventional comb generators based on steprecovery diodes (SRD. Due to the three-terminal structure of the transistor the isolation problem between the input and the output signal of the transistor network is drastically simplified. Furthermore the transistor is an active element in contrast to a SRD, so that its current gain can be used to minimize the power of the driving signal.

  19. Transverse pump-probe microscopy of moving breakdown, filamentation and self-organized absorption in alkali aluminosilicate glass using ultrashort pulse laser.

    Science.gov (United States)

    Grossmann, Daniel; Reininghaus, Martin; Kalupka, Christian; Kumkar, Malte; Poprawe, Reinhart

    2016-10-03

    We present time and space resolved transverse pump-probe measurements of the free electron and defect generation induced by nonlinear absorption of ultra short pulsed laser radiation in unhardened Corning Gorilla glass. The applied setup exhibits a 100 fs probe pulse duration and an independent pump pulse duration up to 5 ps. Hence, our work comprises the absorption of ultra short pulsed laser radiation at a wavelength of 800 nm and pulse energies from 10 μJ to 50 μJ up to a delay of 6 ns. Our investigations reveal different absorption regimes like filamentation and moving breakdown as well as the formation of permanent modifications. Finally, the deposition of multiple pulses in the incubation regime is examined, observing a self-organizing absorption effect.

  20. The new heart of the PS is beating strongly

    CERN Document Server

    Corinne Pralavorio

    2011-01-01

    The PS has resumed operation with a brand new electrical power system called POPS; this enormous system comprising power electronics and capacitors is crucial because if it broke down practically no particles would be able to circulate at CERN. As soon as it started, POPS passed all the tests with flying colours and is now pulsing at full power.   The new PS power system is made up of 6 containers, each with 60 tonnes of capacitors and 8 power converters. The date 11/02/11 will always be remembered with affection by the engineers in the Electrical Power Converters Group. At 11:11 in the morning (no joke), the first beams powered by the new system began to circulate in the PS. The cutely-named POPS (POwer for PS) took over from the old rotating machine that had been working since 1968. From now on it will be POPS that supplies the PS main magnets with the electrical pulses needed to accelerate the beams for the LHC and all CERN's other facilities. The system is crucial as the PS is one of the lyn...

  1. Photostability of a fluorescent marker under pulsed excited-state depletion through stimulated emission.

    Science.gov (United States)

    Dyba, Marcus; Hell, Stefan W

    2003-09-01

    Saturated stimulated-emission depletion (STED) of a fluorescent marker has been shown to break the diffraction barrier in far-field fluorescence microscopy and to facilitate spatial resolution down to a few tens of nanometers. Here we investigate the photostability of a fluorophore that, in this concept, is repeatedly excited and depleted by synchronized laser pulses. Our study of bacteria labeled with RH-414, a membrane marker, reveals that increasing the duration of the STED pulse from approximately 10 to 160 ps fundamentally improves the photostability of the dye. At the same time the STED efficiency is maintained. The observed photobleaching of RH-414 is due primarily to multiphoton absorption from its ground state. One can counteract photobleaching by employing STED pulses that range from 150 ps to approximately half of the lifetime of the excited state. The results also have implications for multiphoton excitation microscopy.

  2. Design and implementation of an FPGA-based timing pulse programmer for pulsed-electron paramagnetic resonance applications.

    Science.gov (United States)

    Sun, Li; Savory, Joshua J; Warncke, Kurt

    2013-08-01

    The design, construction and implementation of a field-programmable gate array (FPGA) -based pulse programmer for pulsed-electron paramagnetic resonance (EPR) experiments is described. The FPGA pulse programmer offers advantages in design flexibility and cost over previous pulse programmers, that are based on commercial digital delay generators, logic pattern generators, and application-specific integrated circuit (ASIC) designs. The FPGA pulse progammer features a novel transition-based algorithm and command protocol, that is optimized for the timing structure required for most pulsed magnetic resonance experiments. The algorithm was implemented by using a Spartan-6 FPGA (Xilinx), which provides an easily accessible and cost effective solution for FPGA interfacing. An auxiliary board was designed for the FPGA-instrument interface, which buffers the FPGA outputs for increased power consumption and capacitive load requirements. Device specifications include: Nanosecond pulse formation (transition edge rise/fall times, ≤3 ns), low jitter (≤150 ps), large number of channels (16 implemented; 48 available), and long pulse duration (no limit). The hardware and software for the device were designed for facile reconfiguration to match user experimental requirements and constraints. Operation of the device is demonstrated and benchmarked by applications to 1-D electron spin echo envelope modulation (ESEEM) and 2-D hyperfine sublevel correlation (HYSCORE) experiments. The FPGA approach is transferrable to applications in nuclear magnetic resonance (NMR; magnetic resonance imaging, MRI), and to pulse perturbation and detection bandwidths in spectroscopies up through the optical range.

  3. Investigation of CIS/CIGS and CdTe solar cells scribing with high-power fibre short pulse lasers

    Science.gov (United States)

    Hernandez, Yves; Lotter, Erwin; Bermudez, Veronica; Bosio, Alessio; Salin, François; Hueske, Marc; Selleri, Stefano; Bertrand, Anthony; Duterte, Charles

    2012-06-01

    We present here some of the last results of the EUROPEAN project ALPINE. We present both the development of an adjustable fibre laser pulse source and scribing results on CdTe and CIGS solar cells. The scribing tests were performed at three different pulse durations: 400 fs, 8 ps and 250 ps. The results obtained with 250 ps are already very promising for P3 steps in both CdTe and CIGS solar cells. In both cases the results were validated electrically. In the case of P3 scribing for CIGS solar cells, shunt resistances as high as 125 kΩ.cm were obtained. Isolation resistances were higher than 1 MΩ.cm. The processing speed was 2 m/s.

  4. Ultrafast Saturation of Electronic-Resonance-Enhanced Coherent Anti-Stokes Raman Scattering and Comparison for Pulse Durations in the Nanosecond to Femtosecond Regime

    Science.gov (United States)

    2016-02-05

    the molecular decay and dephasing timescales, it is very im- portant to understand the ultrafast saturation dynamics of the ERE- CARS . Recently, we...probe with the molecular transition [21]. Although saturation of ERE- CARS with long-pulse excitation has been extensively studied [7, 14], the saturation... molecular levels. Three input pulses ~Ei (i → 1, 2, 3) at frequencies νi generate the CARS signal ~E4 at a frequency ν4 = ν1 − ν2+ν3. The pump ( ~E1

  5. EUV emission stimulated by use of dual laser pulses from continus liquid microjet targets

    Science.gov (United States)

    Higashiguchi, Takeshi; Rajyaguru, Chirag; Sasaki, Wataru; Kubodera, Shoichi

    2004-11-01

    A continuous water-jet or water-jet mixed with LiF with several tens μm diameter was formed in a vacuum chamber through a small capillary nozzle. Usage of two laser pulses is an efficient way to produce EUV emission, since a density and temperature of a plasma formed by the first laser pulse are regulated by the second laser pulse. By adjusting the delay of the second pulse, one could maximize the EUV emission. A subpicosecond Ti:Sapphire laser at a wavelength of 800 nm produced a maximum energy around 30 mJ. The beam was divided by a Michelson interferometer, which produced two laser pulses with energies of 5 mJ. The pulse duration was adjusted around 300 fs (FWHM). Both beams were focused on a micro-jet using a lens with a focal length of 15 cm. The delay time between the two pulses was varied from 100 to 800 ps by use of an optical delay line. Clear enhancement of the EUV emission yield was observed when the delay between the two pulses was around 500 ps. The experimentally observed delay agrees reasonably well with that of a plasma to expand to its critical density of 10^21 cm-3.

  6. SPS and PS Experiments Committee

    CERN Multimedia

    CERN. Geneva

    2004-01-01

    OPEN SESSION: 09:00 Status report of NA58 / COMPASS: A. Magnon 09:40 Status report of PS212 / DIRAC: L. Tausher 10:10 PS212 / DIRAC Addendum: L. Nemenov CLOSED SESSION on Tuesday, 27 April 2004 after the open session, Main Building, 6th floor conference room

  7. Mode-locked pulses from mid-infrared quantum cascade lasers.

    Science.gov (United States)

    Wang, Christine Y; Kuznetsova, Lyuba; Gkortsas, V M; Diehl, L; Kärtner, F X; Belkin, M A; Belyanin, A; Li, X; Ham, D; Schneider, H; Grant, P; Song, C Y; Haffouz, S; Wasilewski, Z R; Liu, H C; Capasso, Federico

    2009-07-20

    In this study, we report the unequivocal demonstration of midinfrared mode-locked pulses from quantum cascade lasers. The train of short pulses was generated by actively modulating the current and hence the gain of an edge-emitting quantum cascade laser (QCL). Pulses with duration of about 3 ps at full-width-at-half-maxima and energy of 0.5 pJ were characterized using a second-order interferometric autocorrelation technique based on a nonlinear quantum well infrared photodetector. The mode-locking dynamics in the QCLs was modeled based on the Maxwell-Bloch equations in an open two-level system. Our model reproduces the overall shape of the measured autocorrelation traces and predicts that the short pulses are accompanied by substantial wings as a result of strong spatial hole burning. The range of parameters where short mode-locked pulses can be formed is found.

  8. Generation of a passively Q-switched mode-locked pulse from a laser diode pumped Nd:YAG laser

    CERN Document Server

    Jeong, T M; Kim, C J; Nam, C H

    1999-01-01

    A passively Q-switched, mode-locked pulse was generated from a laser diode pumped Nd:YAG laser. The passive Q-switching was performed by using a Cr sup 4 sup + :YAG saturable absorber. The mode-locked pulse inside the Q-switched pulse was obtained by using a nonlinear mirror mode-locking without any tight focusing geometry. With a Cr sup 4 sup + :YAG saturable absorber and a nonlinear mirror mode locking method, a mode-locked pulse with a pulse width of less than 600 ps and a repetition rate of 714 MHz was obtained inside a Q-switched pulse envelope with a temporal duration of 80 ns and a repetition rate of about 2 kHz.

  9. All-fiber passively mode-locked Tm-doped NOLM-based oscillator operating at 2-μm in both soliton and noisy-pulse regimes.

    Science.gov (United States)

    Li, Jianfeng; Zhang, Zuxing; Sun, Zhongyuan; Luo, Hongyu; Liu, Yong; Yan, Zhijun; Mou, Chengbo; Zhang, Lin; Turitsyn, Sergei K

    2014-04-07

    A self-starting all-fiber passively mode-locked Tm(3+)-doped fiber laser based on nonlinear loop mirror (NOLM) is demonstrated. Stable soliton pulses centered at 2017.33 nm with 1.56 nm FWHM were produced at a repetition rate of 1.514 MHz with pulse duration of 2.8 ps and pulse energy of 83.8 pJ. As increased pump power, the oscillator can also operate at noise-like (NL) regime. Stable NL pulses with coherence spike width of 341 fs and pulse energy of up to 249.32 nJ was achieved at a center wavelength of 2017.24 nm with 21.33 nm FWHM. To the best of our knowledge, this is the first 2 µm region NOLM-based mode-locked fiber laser operating at two regimes with the highest single pulse energy for NL pulses.

  10. Laser-induced retinal damage threshold for repetitive-pulse exposure to 100-microsecs pulses

    Science.gov (United States)

    2014-10-07

    and 1000 Hz (Fig. 3). In Fig. 4, PS model predictions based on the experimentally determined single pulse ED50 and probit slope are compared to the...pulse repetition frequencies. The variation of the ED50 with the number of pulses is described well by the probability summation model , in which each...summation (PS) model of Menendez et al.15–17 For this injury mechanism, the cumulative threshold is depen dent only on the number of pulses in the exposure

  11. Pressure Monitoring Using Hybrid fs/ps Rotational CARS

    Science.gov (United States)

    Kearney, Sean P.; Danehy, Paul M.

    2015-01-01

    We investigate the feasibility of gas-phase pressure measurements at kHz-rates using fs/ps rotational CARS. Femtosecond pump and Stokes pulses impulsively prepare a rotational Raman coherence, which is then probed by a high-energy 6-ps pulse introduced at a time delay from the Raman preparation. Rotational CARS spectra were recorded in N2 contained in a room-temperature gas cell for pressures from 0.1 to 3 atm and probe delays ranging from 10-330 ps. Using published self-broadened collisional linewidth data for N2, both the spectrally integrated coherence decay rate and the spectrally resolved decay were investigated as means for detecting pressure. Shot-averaged and single-laser-shot spectra were interrogated for pressure and the accuracy and precision as a function of probe delay and cell pressure are discussed. Single-shot measurement accuracies were within 0.1 to 6.5% when compared to a transducer values, while the precision was generally between 1% and 6% of measured pressure for probe delays of 200 ps or more, and better than 2% as the delay approached 300 ps. A byproduct of the pressure measurement is an independent but simultaneous measurement of the gas temperature.

  12. Laser diode structures with a saturable absorber for high-energy picosecond optical pulse generation by combined gain-and Q-switching

    Science.gov (United States)

    Ryvkin, B. S.; Avrutin, E. A.; Kostamovaara, J. E. K.; Kostamovaara, J. T.

    2017-02-01

    The performance of gain-switched Fabry-Perot asymmetric-waveguide semiconductor lasers with a large equivalent spot size and an intracavity saturable absorber was investigated experimentally and theoretically. The laser with a short (˜20 μm) absorber emitted high-energy afterpulse-free optical pulses in a broad range of injection current pulse amplitudes; optical pulses with a peak power of about 35 W and a duration of about 80 ps at half maximum were achieved with a current pulse with an amplitude of just 8 A and a duration of 1.5 ns. Good quality pulsations were observed in a broad range of elevated temperatures. The introduction of a substantially longer absorber section leads to strong spectral broadening of the output without a significant improvement to pulse energy and peak power.

  13. The PS will soon be back in operation

    CERN Multimedia

    2006-01-01

    The PS's power supply system is undergoing repairs for the accelerator to restart on 26 June. The AB Department's Power Converter Group is working flat out with Siemens to return the PS's power supply system to working order. A problem appeared on the insulation of the power cables of the rotor of the rotating machine (photo) which supplies power to the PS magnets. To prevent more significant damage to the rotating machine, the AB Department, with the approval of the CERN Management, decided to shut down the PS which had started running on 15 May. Everything is being done to restart the accelerator on 26 June. The PS's rotating machine comprises a motor coupled to a generator. The generator's rotor acts like a flywheel, supplying high-power pulses of 40 to 50 megawatts to the PS magnets. The 6 megawatt motor drives the installation at 1000 revolutions per minute and compensates only for variations in speed. It is an essential interface since it would be hard to imagine connecting such an electrical charge, p...

  14. Area dependence of femtosecond laser-induced periodic surface structures for varying band gap materials after double pulse excitation

    Energy Technology Data Exchange (ETDEWEB)

    Höhm, S., E-mail: Hoehm@mbi-berlin.de [Max-Born-Institut für Nichtlineare Optik und Kurzzeitspektroskopie (MBI), Max-Born-Straße 2A, D-12489 Berlin (Germany); Rosenfeld, A. [Max-Born-Institut für Nichtlineare Optik und Kurzzeitspektroskopie (MBI), Max-Born-Straße 2A, D-12489 Berlin (Germany); Krüger, J.; Bonse, J. [BAM Bundesanstalt für Materialforschung und -prüfung, Unter den Eichen 87, D-12205 Berlin (Germany)

    2013-08-01

    The formation of laser-induced periodic surface structures upon irradiation of titanium, silicon, and fused silica with multiple irradiation sequences consisting of parallel polarized Ti:sapphire femtosecond laser pulse pairs (pulse duration 50–150 fs, central wavelength ∼800 nm) is studied experimentally. The temporal delay between the individual near-equal energy fs-laser pulses was varied between 0 and 5 ps with a temporal resolution of better than 0.2 ps. The surface morphology of the irradiated surface areas is characterized by means of scanning electron microscopy (SEM). In all materials a decrease of the rippled surface area is observed for increasing delays. The characteristic delay decay scale is quantified and related to material dependent excitation and energy relaxation processes.

  15. Current characteristics of quasi-planar vacuum diodes with explosive-emission cathodes made of various materials at a high-voltage pulse duration of a few nanoseconds

    Science.gov (United States)

    Afanas'ev, K. V.; Vagner, M. I.; Kutenkov, O. P.; Pegel, I. V.; Pribytkov, G. A.; Rostov, V. V.; Tarakanov, V. P.

    2012-12-01

    The currents of 5-ns pulsed high-current electron beams produced in a planar vacuum diode with explosive-emission cathodes made of various materials with no external magnetic field at an average electric field strength in the gap of about 300 kV/cm have been measured and time-integrated observation of the optical luminescence of the cathode surface have been performed. Cathodes with a ceramic bushing and spring metal contacts, with ceramic plates set in a magnetic iron matrix, with blades made of stamped exfoliated graphite (Graflex), with blades made of foil fiberglass plastic, and a composite cathode made of crystalline boron and copper powders were tested. The current carried by one emission center has been estimated to range between 5 and 20 A for various cathodes. For the metal-dielectric cathode, the velocity of expansion of the cathode plasma over the ceramic surface has been estimated as 2·107 cm/s. The lifetimes of the cathodes at a pulse repetition rate of 50 Hz have been investigated.

  16. Ultra-fast ballistic magnetization reversal triggered by a single magnetic field pulse

    Energy Technology Data Exchange (ETDEWEB)

    Horley, Paul P; Gonzalez Hernandez, Jesus [Centro de Investigacion en Materiales Avanzados S.C., Chihuahua/Monterrey, Av. Miguel de Cervantes 120, 31109 Chihuahua, Chihuahua (Mexico); Vieira, Vitor R; Dugaev, Vitalii K [Centro de Fisica das Interaccoes Fundamentais, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Avenida Rovisco Pais, 1049-001 Lisbon (Portugal); Gorley, Peter [Department of Physics, Yuri Fedkovych Chernivtsi National University, 2 Kotsyubynsky Street, 58012 Chernivtsi (Ukraine); Barnas, Jozef, E-mail: paul.horley@cimav.edu.m [Institute of Molecular Physics, Polish Academy of Sciences, ul. Smoluchowskiego 17, 60-179 Poznan (Poland)

    2009-12-21

    Performance of devices such as magnetic random access memories crucially depends on magnetic switching time. By numerical simulations we show that ultra-fast (in the sub-nanosecond range) magnetic reversal in nanoparticles can be achieved with a single pulse of magnetic field oriented at some specific angles with respect to the magnetic moment. These angles form the areas of ballistic reversal (with no magnetization ringing). We show that the size of these areas increases with decreasing pulse duration, which allows reaching of the sub-nanosecond reversal for a pulse duration of the order of dozen(s) of ps. When changing the magnetic field, the areas of ballistic reversal move along the equator of the unitary sphere, and eventually merge with each other. For appropriate choice of the azimuthal angle, one can reach magnetic reversal along a trajectory located in or out of the easy plane.

  17. Generation of synchronized signal and pump pulses for an optical ...

    Indian Academy of Sciences (India)

    Abstract. Synchronized signal (650 ps) and pump (1.3 ns) pulses were generated using. 4-pass geometry in a grating pair based pulse stretcher unit. The pump pulse has been further amplified in a high gain regenerative amplifier. This amplified pulse was used as the pump in an optical parametric chirped pulse ...

  18. The influence of ultra-fast temporal energy regulation on the morphology of Si surfaces through femtosecond double pulse laser irradiation

    Science.gov (United States)

    Barberoglou, M.; Tsibidis, G. D.; Gray, D.; Magoulakis, E.; Fotakis, C.; Stratakis, E.; Loukakos, P. A.

    2013-11-01

    The effect of ultra-short laser-induced morphological changes upon irradiation of silicon with double pulse sequences is investigated under conditions that lead to mass removal. The temporal delay between 12 double and equal-energy pulses ( E p=0.24 J/cm2 each, with pulse duration t p=430 fs, 800 nm laser wavelength) was varied between 0 and 14 ps and a decrease of the damaged area, crater depth size and periodicity of the induced subwavelength ripples (by 3-4 %) was observed with increasing pulse delay. The proposed underlying mechanism is based on the combination of carrier excitation and energy thermalization and capillary wave solidification and aims to provide an alternative explanation of the control of ripple periodicity by temporal pulse tailoring. This work demonstrates the potential of pulse shaping technology to improve ultra-fast laser-assisted micro/nanoprocessing.

  19. A Novel Low-Ringing Monocycle Picosecond Pulse Generator Based on Step Recovery Diode

    Science.gov (United States)

    Zhou, Jianming; Yang, Xiao; Lu, Qiuyuan; Liu, Fan

    2015-01-01

    This paper presents a high-performance low-ringing ultra-wideband monocycle picosecond pulse generator, formed using a step recovery diode (SRD), simulated in ADS software and generated through experimentation. The pulse generator comprises three parts, a step recovery diode, a field-effect transistor and a Schottky diode, used to eliminate the positive and negative ringing of pulse. Simulated results validate the design. Measured results indicate an output waveform of 1.88 peak-to-peak amplitude and 307ps pulse duration with a minimal ringing of -22.5 dB, providing good symmetry and low level of ringing. A high degree of coordination between the simulated and measured results is achieved. PMID:26308450

  20. Dual square-wave pulse passively mode-locked fiber laser.

    Science.gov (United States)

    Su, Qingchao; Wang, Tianshu; Zhang, Jing; Ma, Wanzhuo; Liu, Peng; Su, Yuwei; Jia, Qingsong

    2017-06-10

    We study a passively mode-locked square-wave pulse (SWP) fiber laser with a nonlinear amplifying loop mirror in the cavity. The net dispersion of the cavity is about 0.68  ps2 and the SWP mode-locked fiber laser can be realized. The peak power of the SWP hardly varies and the pulse duration gets expanded with the increasing pump power. SWPs breaking in the low nonlinear cavity can be observed and the stable dual SWP can be achieved in the experiment. When the total pump power stays at 800 mW, the interval of dual pulses is 41 ns. The widths of dual SWPs are both 1.5 ns. The output power rises linearly with the increasing of the pump power, while the interval of dual SWPs is almost constant. Then, the physical mechanism of the SWP breaking and vector nature of the pulse are analyzed.

  1. A Novel Low-Ringing Monocycle Picosecond Pulse Generator Based on Step Recovery Diode.

    Directory of Open Access Journals (Sweden)

    Jianming Zhou

    Full Text Available This paper presents a high-performance low-ringing ultra-wideband monocycle picosecond pulse generator, formed using a step recovery diode (SRD, simulated in ADS software and generated through experimentation. The pulse generator comprises three parts, a step recovery diode, a field-effect transistor and a Schottky diode, used to eliminate the positive and negative ringing of pulse. Simulated results validate the design. Measured results indicate an output waveform of 1.88 peak-to-peak amplitude and 307ps pulse duration with a minimal ringing of -22.5 dB, providing good symmetry and low level of ringing. A high degree of coordination between the simulated and measured results is achieved.

  2. Generating picosecond x-ray pulses in synchrotron light sources using dipole kickers

    Directory of Open Access Journals (Sweden)

    W. Guo

    2007-02-01

    Full Text Available The duration of the x-ray pulse generated at a synchrotron light source is typically tens of picoseconds. Shorter pulses are highly desired by the users. In electron storage rings, the vertical beam size is usually orders of magnitude less than the bunch length due to radiation damping; therefore, a shorter pulse can be obtained by slitting the vertically tilted bunch. Zholents proposed tilting the bunch using rf deflection. We found that tilted bunches can also be generated by a dipole magnet kick. A vertical tilt is developed after the kick in the presence of nonzero chromaticity. The tilt was successfully observed and a 4.2-ps pulse was obtained from a 27-ps electron bunch at the Advanced Photon Source. Based on this principle, we propose a short-pulse generation scheme that produces picosecond x-ray pulses at a repetition rate of 1–2 kHz, which can be used for pump-probe experiments.

  3. Strip velocity measurements for gated x-ray imagers using short pulse lasers

    Science.gov (United States)

    Ross, P. W.; Cardenas, M.; Griffin, M.; Mead, A.; Silbernagel, C. T.; Bell, P.; Haque, S.

    2013-09-01

    Strip velocity measurements of gated X-ray imagers are presented using an ultra-short pulse laser. Obtaining time- resolved X-ray images of inertial confinement fusion shots presents a difficult challenge. One diagnostic developed to address this challenge is the gated X-ray imagers. The gated X-ray detectors (GXDs) developed by Lawrence Livermore National Laboratory and Los Alamos National Laboratory use a microchannel plate (MCP) coated with a gold strip line, which serves as a photocathode. GXDs are used with an array of pinholes, which image onto various parts of the GXD image plane. As the pulse sweeps over the strip lines, it creates a time history of the event with consecutive images. In order to accurately interpret the timing of the images obtained using the GXDs, it is necessary to measure the propagation of the pulse over the strip line. The strip velocity was measured using a short pulse laser with a pulse duration of approximately 1-2 ps. The 200nm light from the laser is used to illuminate the GXD MCP. The laser pulse is split and a retroreflective mirror is used to delay one of the legs. By adjusting the distance to the mirror, one leg is temporally delayed compared to the reference leg. The retroreflective setup is calibrated using a streak camera with a 1 ns full sweep. Resolution of 0.5 mm is accomplished to achieve a temporal resolution of ~5 ps on the GXD strip line.

  4. Laser-induced periodic surface structures on fused silica upon cross-polarized two-color double-fs-pulse irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Höhm, S., E-mail: hoehm@mbi-berlin.de.de [Max-Born-Institut für Nichtlineare Optik und Kurzzeitspektroskopie (MBI), Max-Born-Straße 2A, D-12489 Berlin (Germany); Herzlieb, M.; Rosenfeld, A. [Max-Born-Institut für Nichtlineare Optik und Kurzzeitspektroskopie (MBI), Max-Born-Straße 2A, D-12489 Berlin (Germany); Krüger, J. [BAM Bundesanstalt für Materialforschung und–prüfung, Unter den Eichen 87, D-12205 Berlin (Germany); Bonse, J., E-mail: joern.bonse@bam.de [BAM Bundesanstalt für Materialforschung und–prüfung, Unter den Eichen 87, D-12205 Berlin (Germany)

    2015-05-01

    Graphical abstract: - Highlights: • LIPSS formation on fused silica is studied upon cross-polarized two-color (400 and 800 nm) double-fs-pulse irradiation. • LIPSS orientation follows the polarization of the first pulse. • LIPSS periods are determined by the wavelength of the first pulse. • LIPSS area is increased for temporally overlapping pulses due to nonlinear absorption. - Abstract: The dynamics of the formation of laser-induced periodic surface structures (LIPSS) on fused silica upon irradiation with linearly polarized fs-laser pulses (50 fs pulse duration) is studied by cross-polarized two-color double-fs-pulse experiments. In order to analyze the relevance of temporally distributed energy deposition in the early stage of LIPSS formation, a Mach-Zehnder interferometer was used for generating multiple double-pulse sequences at two different wavelengths (400 and 800 nm). The inter-pulse delay between the individual cross-polarized pulses of each sequence was systematically varied in the sub-ps range and the resulting LIPSS morphologies were characterized by scanning electron microscopy. It is found that the polarization of the first laser pulse arriving to the surface determines the orientation and the periodicity of the LIPSS. These two-color experiments further confirm the importance of the ultrafast energy deposition to the silica surface for LIPSS formation, particularly by the first laser pulse of each sequence. The second laser pulse subsequently reinforces the previously seeded spatial LIPSS characteristics (period, orientation)

  5. The PS locomotive runs again

    CERN Multimedia

    2001-01-01

    Over forty years ago, the PS train entered service to steer the magnets of the accelerator into place... ... a service that was resumed last Tuesday. Left to right: Raymond Brown (CERN), Claude Tholomier (D.B.S.), Marcel Genolin (CERN), Gérard Saumade (D.B.S.), Ingo Ruehl (CERN), Olivier Carlier (D.B.S.), Patrick Poisot (D.B.S.), Christian Recour (D.B.S.). It is more than ten years since people at CERN heard the rumbling of the old PS train's steel wheels. Last Tuesday, the locomotive came back into service to be tested. It is nothing like the monstrous steel engines still running on conventional railways -just a small electric battery-driven vehicle employed on installing the magnets for the PS accelerator more than 40 years ago. To do so, it used the tracks that run round the accelerator. In fact, it is the grandfather of the LEP monorail. After PS was commissioned in 1959, the little train was used more and more rarely. This is because magnets never break down, or hardly ever! In fact, the loc...

  6. The PS Booster hits 40

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    Many accelerators’ "round" birthdays are being celebrated at CERN these days – the PS turned 50 in 2009, the SPS was 35 in 2011, and this year it's the turn of the PS Booster to mark its 40th anniversary. Originally designed to accelerate 1013 protons to 800 MeV, it has far exceeded its initial design performance over the years.   The PS Booster in the 1970s. Imagine the scene: a group of accelerator physicists staring expectantly at a monitor, when suddenly a shout of joy goes up as a signal flickers across the screen. Does that sound familiar? Well, turn the clock back 40 years (longer hair, wider trouser legs) and you have the situation at the PS Booster on 26 May 1972. On that day, beam was injected into the Booster for the first time. “It was a real buzz,” says Heribert Koziol, then Chairman of the Running-in Committee. “We were very happy – and also a little relieved – when the beam finally...

  7. High speed, high current pulsed driver circuit

    Science.gov (United States)

    Carlen, Christopher R.

    2017-03-21

    Various technologies presented herein relate to driving a LED such that the LED emits short duration pulses of light. This is accomplished by driving the LED with short duration, high amplitude current pulses. When the LED is driven by short duration, high amplitude current pulses, the LED emits light at a greater amplitude compared to when the LED is driven by continuous wave current.

  8. Theoretical and experimental study of superradiance pulse generation by heavy-current subnanosecond electron bunches moving in periodic slowing down system

    CERN Document Server

    Ginzburg, N S; Novozhilova, Y V; Sergeev, A S; Shpak, V G; Shunailov, S A; Ul'maskulov, M R; Yalandin, M I

    2002-01-01

    One studied both theoretically and experimentally the Cherenkov superradiance at liner motion of an electron bunch through the periodic slowing down system. Simulations in terms of the KARAT code show that peak intensity of microwave pulses is proportional to the square of total number of particles in a bunch. This finding os conformed experimentally. As a results, at 39 GHz frequency one obtained ultrashort pulses of up to 140 MW high intensity and with 30 ps duration. The RADAN 303 high-current subnanosecond accelerator injected electron bunches with up to 2 A current, 0.5-1.5 ns duration and 200-300 keV particle energy was used as a source of electrons. Simulation shows possibility of further intensification of electromagnetic pulses up to 300-400 MW due to optimization of parameters of accelerating voltage pulse

  9. Cr{sup 4+} : YAG chirped-pulse oscillator

    Energy Technology Data Exchange (ETDEWEB)

    Sorokin, Evgeni; Kalashnikov, Vladimir L [Institut fuer Photonik, TU Wien, Gusshausstr. 27/387, A-1040 Vienna (Austria); Mandon, Julien; Guelachvili, Guy; Picque, Nathalie [Laboratoire de Photophysique Moleculaire, CNRS, Universite Paris-Sud, Batiment 350, 91405 Orsay Cedex (France); Sorokina, Irina T [Department of Physics, Norwegian University of Science and Technology, N-7491 Trondheim (Norway)], E-mail: evgeni.sorokin@tuwien.ac.at

    2008-08-15

    We demonstrate chirped-pulse operation of a Cr : YAG passively mode-locked laser. Different operation regimes of the laser are extensively investigated in the vicinity of zero dispersion both experimentally and numerically. It is shown that for a given laser configuration, transition to the positive dispersion regime allows a 5-fold increase in the output pulse energy, which is otherwise limited by the onset of the multipulsing or 'chaotic' mode-locking. The output pulses have 1.4 ps duration and are compressible down to 120 fs in a 3 m piece of silica fiber, enabling supercontinuum generation in a nonlinear fiber. The spectrum shape and operation stability of the chirped-pulse regime depend strongly on the amount and shape of the intracavity dispersion. The numerical model predicts the existence of the minimum amount of the positive dispersion, above which the chirped-pulse regime can be realized. Once located, the chirped-pulse regime can be reliably reproduced and is sufficiently stable for applications.

  10. All-Fiber, Directly Chirped Laser Source for Chirped-Pulse-Amplification

    Science.gov (United States)

    Xin, Ran

    Chirped-pulse-amplification (CPA) technology is widely used to produce ultra-short optical pulses (sub picosecond to femtoseconds) with high pulse energy. A chirped pulse laser source with flexible dispersion control is highly desirable as a CPA seed. This thesis presents an all-fiber, directly chirped laser source (DCLS) that produces nanosecond, linearly-chirped laser pulses at 1053 nm for seeding high energy CPA systems. DCLS produces a frequency chirp on an optical pulse through direct temporal phase modulation. DCLS provides programmable control for the temporal phase of the pulse, high pulse energy and diffraction-limited beam performance, which are beneficial for CPA systems. The DCLS concept is first described. Its key enabling technologies are identified and their experimental demonstration is presented. These include high-precision temporal phase control using an arbitrary waveform generator, multi-pass phase modulation to achieve high modulation depth, regenerative amplification in a fiber ring cavity and a negative feedback system that controls the amplifier cavity dynamics. A few technical challenges that arise from the multi-pass architecture are described and their solutions are presented, such as polarization management and gain-spectrum engineering in the DCLS fiber cavity. A DCLS has been built and its integration into a high energy OPCPA system is demonstrated. DCLS produces a 1-ns chirped pulse with a 3-nm bandwidth. The temporal phase and group delay dispersion on the DCLS output pulse is measured using temporal interferometry. The measured temporal phase has an ˜1000 rad amplitude and is close to a quadratic shape. The chirped pulse is amplified from 0.9 nJ to 76 mJ in an OPCPA system. The amplified pulse is compressed to close to its Fourier transform limit, producing an intensity autocorrelation trace with a 1.5-ps width. Direct compressed-pulse duration control by adjusting the phase modulation drive amplitude is demonstrated. Limitation

  11. High precision laser direct microstructuring system based on bursts of picosecond pulses

    Science.gov (United States)

    Mur, Jaka; Petelin, Jaka; Osterman, Natan; Petkovšek, Rok

    2017-08-01

    We have developed an efficient, high precision system for direct laser microstructuring using fiber laser generated bursts of picosecond pulses. An advanced opto-mechanical system for beam deflection and sample movement, precise pulse energy control, and a custom built fiber laser with the pulse duration of 65 ps have been combined in a compact setup. The setup allows structuring of single-micrometer sized objects with a nanometer resolution of the laser beam positioning due to a combination of acousto-optical laser beam deflection and tight focusing. The precise synchronization of the fiber laser with the pulse burst repetition frequency of up to 100 kHz allowed a wide range of working parameters, including a tuneable number of pulses in each burst with the intra-burst repetition frequency of 40 MHz and delivering exactly one burst of pulses to every chosen position. We have demonstrated that tightly focused bursts of pulses significantly increase the ablation efficiency during the microstructuring of a copper layer and shorten the typical processing time compared to the single pulse per spot regime. We have used a simple short-pulse ablation model to describe our single pulse ablation data and developed an upgrade to the model to describe the ablation with bursts. Bursts of pulses also contribute to a high quality definition of structure edges and sides. The increased ablation efficiency at lower pulse energies compared to the single pulse per spot regime opens a window to utilize compact fiber lasers designed to operate at lower pulse energies, reducing the overall system complexity and size.

  12. Technical advantages of disk laser technology in short and ultrashort pulse processes

    Science.gov (United States)

    Graham, P.; Stollhof, J.; Weiler, S.; Massa, S.; Faisst, B.; Denney, P.; Gounaris, E.

    2011-03-01

    This paper demonstrates that disk-laser technology introduces advantages that increase efficiency and allows for high productivity in micro-processing in both the nanosecond (ns) and picosecond (ps) regimes. Some technical advantages of disk technology include not requiring good pump beam quality or special wavelengths for pumping of the disk, high optical efficiencies, no thermal lensing effects and a possible scaling of output power without an increase of pump beam quality. With cavity-dumping, the pulse duration of the disk laser can be specified between 30 and hundreds of nanoseconds, but is independent of frequency, thus maintaining process stability. TRUMPF uses this technology in the 750 watts average power laser TruMicro 7050. High intensity, along with fluency, is important for high ablation rates in thinfilm removal. Thus, these ns lasers show high removal rates, above 60 cm2/s, in thin-film solar cell production. In addition, recent results in paint-stripping of aerospace material prove the green credentials and high processing rates inherent with this technology as it can potentially replace toxic chemical processes. The ps disk technology meanwhile is used in, for example, scribing of solar cells, wafer dicing and drilling injector nozzles, as the pulse duration is short enough to minimize heat input in the laser-matter interaction. In the TruMicro Series 5000, the multi-pass regenerative amplifier stage combines high optical-optical efficiencies together with excellent output beam quality for pulse durations of only 6 ps and high pulse energies of up to 0.25 mJ.

  13. Time-resolved microscopy using variable probe wavelengths for ultra-short pulse interaction (Conference Presentation)

    Science.gov (United States)

    Bergner, Klaus; Kumkar, Malte; Tünnermann, Andreas; Nolte, Stefan; Seyfarth, Brian

    2017-03-01

    Glass processing with ultrashort laser pulses allow for different material modifications, ranging from smooth refractive index changes which can be used for the generation of waveguides up to large disruptions due to accumulates stress for glass separation. These disruptions, generated by a dense electron plasma, are favored for glass dicing applications. To tailor the resulting material response a fundamental understanding of the laser/material interaction is of interest. Therefore, we analyze the spatio-temporal evolution of free carriers induced by ultrashort laser pulses using a pump-probe setup with high temporal and spatial resolution and various probe wavelengths. Single laser pulses with 1026nm wavelength, 6ps (FWHM) pulse duration and 200μJ pulse energy were applied to fused silica, Borofloat 33 and Gorilla glass. Electron densities around 1 x 1020cm-3 in the focal plane and 1 x 1019cm-3 in front of the focus are obtained, independent from the glass type used. The free carriers slowly decay within several ns, while the decay time depends on both the maximum electron densities reached and glass species. In this process a part of the excited electrons relax within several 10ps into a long-living stage where a transient effect is observed. Here, various probe wavelengths show differences in the recorded signal. A further carrier relaxation leads to permanent (stress, voids) and non-stable (color center) modifications crucial for precise glass dicing applications.

  14. A short-pulse X-ray beamline for spectroscopy and scattering.

    Science.gov (United States)

    Reininger, R; Dufresne, E M; Borland, M; Beno, M A; Young, L; Evans, P G

    2014-09-01

    Experimental facilities for picosecond X-ray spectroscopy and scattering based on RF deflection of stored electron beams face a series of optical design challenges. Beamlines designed around such a source enable time-resolved diffraction, spectroscopy and imaging studies in chemical, condensed matter and nanoscale materials science using few-picosecond-duration pulses possessing the stability, high repetition rate and spectral range of synchrotron light sources. The RF-deflected chirped electron beam produces a vertical fan of undulator radiation with a correlation between angle and time. The duration of the X-ray pulses delivered to experiments is selected by a vertical aperture. In addition to the radiation at the fundamental photon energy in the central cone, the undulator also emits the same photon energy in concentric rings around the central cone, which can potentially compromise the time resolution of experiments. A detailed analysis of this issue is presented for the proposed SPXSS beamline for the Advanced Photon Source. An optical design that minimizes the effects of off-axis radiation in lengthening the duration of pulses and provides variable X-ray pulse duration between 2.4 and 16 ps is presented.

  15. [Alternatives to femtosecond laser technology: subnanosecond UV pulse and ring foci for creation of LASIK flaps].

    Science.gov (United States)

    Vogel, A; Freidank, S; Linz, N

    2014-06-01

    In refractive corneal surgery femtosecond (fs) lasers are used for creating LASIK flaps, dissecting lenticules and for astigmatism correction by limbal incisions. Femtosecond laser systems are complex and expensive and cutting precision is compromised by the large focal length associated with the commonly used infrared (IR) wavelengths. Based on investigations of the cutting dynamics, novel approaches for corneal dissection using ultraviolet A (UVA) picosecond (ps) pulses and ring foci from vortex beams are presented. Laser-induced bubble formation in corneal stroma was investigated by high-speed photography at 1-50 million frames/s. Using Gaussian and vortex beams of UVA pulses with durations between 200 and 850 ps the laser energy needed for easy removal of flaps created in porcine corneas was determined and the quality of the cuts by scanning electron microscopy was documented. Cutting parameters for 850 ps are reported also for rabbit eyes. The UV-induced and mechanical stress were evaluated for Gaussian and vortex beams. The results show that UVA picosecond lasers provide better cutting precision than IR femtosecond lasers, with similar processing times. Cutting energy decreases by >50 % when the laser pulse duration is reduced to 200 ps. Vortex beams produce a short, donut-shaped focus allowing efficient and precise dissection along the corneal lamellae which results in a dramatic reduction of the absorbed energy needed for cutting and of mechanical side effects as well as in less bubble formation in the cutting plane. A combination of novel approaches for corneal dissection provides the option to replace femtosecond lasers by compact UVA microchip laser technology. Ring foci are also of interest for femtosecond laser surgery, especially for improved lenticule excision.

  16. High average power difference-frequency generation of picosecond mid-IR pulses at 80MHz using an Yb-fiber laser pumped optical parametric oscillator

    Science.gov (United States)

    Michel, Julia; Beutler, Marcus; Rimke, Ingo; Büttner, Edlef; Farinello, Paolo; Agnesi, Antonio; Petrov, Valentin P.

    2015-02-01

    We present an efficient coherent source widely tunable in the mid-infrared spectral range consisting of a commercial picosecond Yb-fiber laser operating at 80 MHz repetition rate, a synchronously-pumped OPO (SPOPO) and differencefrequency generation (DFG) in AgGaSe2. With an average input pump power of 7.8 W at 1032 nm and at 80 MHz, the SPOPO outputs are tunable from 1380 to 1980 nm (Signal) and from 2.1 to ~4 μm (Idler) with pulse durations between 2.1 and 2.6 ps over the entire tuning range. After temporally overlapping Signal and Idler through a delay line, the two beams are spatially recombined with a dichroic mirror (reflecting for the Signal in s-polarization and transmitting for the Idler in p-polarization), and focused by a 150 mm CaF2 lens to a common focus. For DFG we employ an AR-coated 10- mm thick AgGaSe2 nonlinear crystal cut for type-I interaction at θ =52°. The generated mid-infrared picosecond pulses are continuously tunable between 5 and 18 μm with average power up to 130 mW at 6 μm and more than 1 mW at 18 μm. Their spectra and autocorrelation traces are measured up to 15 μm and 11 μm, respectively, and indicate that the input spectral bandwidth and pulse duration are maintained to a great extent in the nonlinear frequency conversion processes. The pulse duration slightly decreases from 2.1 to 1.9 ps at 6.7 μm while the spectral bandwidth supports ~1.5 ps (~10 cm-1)durations across the entire mid-infrared tuning range. For the first time narrow-band mid-infrared pulses with energy exceeding 1 nJ are generated at such high repetition rates.

  17. High-power terahertz optical pulse generation with a dual-wavelength harmonically mode-locked Yb:YAG laser

    Science.gov (United States)

    Zhuang, W. Z.; Chang, M. T.; Su, K. W.; Huang, K. F.; Chen, Y. F.

    2013-07-01

    We report on high-power terahertz optical pulse generation with a dual-wavelength harmonically mode-locked Yb:YAG laser. A semiconductor saturable absorber mirror is developed to achieve synchronously mode-locked operation at two spectral bands centered at 1031.67 and 1049.42 nm with a pulse duration of 1.54 ps and a pulse repetition rate of 80.3 GHz. With a diamond heat spreader to improve the heat removal efficiency, the average output power can be up to 1.1 W at an absorbed pump power of 5.18 W. The autocorrelation traces reveal that the mode-locked pulse is modulated with a beat frequency of 4.92 THz and displays a modulation depth to be greater than 80%.

  18. Mechanistic investigation of doxycycline photosensitization by picosecond-pulsed and continuous wave laser irradiation of cells in culture

    Energy Technology Data Exchange (ETDEWEB)

    Shea, C.R.; Hefetz, Y.; Gillies, R.; Wimberly, J.; Dalickas, G.; Hasan, T. (Massachusetts General Hospital, Boston (USA))

    1990-04-15

    In order to elucidate the photophysical mechanisms of cellular phototoxicity sensitized by doxycycline, MGH-U1 human bladder carcinoma cells in vitro were treated with 20.7 microM doxycycline and irradiated with either a pulsed (lambda = 355 nm, pulse duration = 24 ps) or a continuous wave (lambda = 351 nm) laser. Cumulative radiant exposure and irradiance were systematically varied in experiments with both lasers. Phototoxicity was assessed by epifluorescence microscopy of unfixed cells using rhodamine 123 labeling of mitochondria. With the continuous wave source, the cumulative radiant exposure required for induction of phototoxic injury was independent of irradiance. With the 24-ps-pulsed source, a significantly lower cumulative radiant exposure was required to induce the phototoxicity when the peak irradiance was 5.8 x 10(7) or 1.3 x 10(8) watts cm-2 compared with when peak irradiance was either lower (6.0 x 10(6) watts cm-2) or higher (7.6 x 10(8) watts cm-2). The measured fluorescence lifetimes of doxycycline in buffered saline solution were longer than the laser pulse duration of 24 ps. The increased efficiency of photosensitization at the optimal peak irradiance in the ps domain appears to result from sequential multiphoton absorption involving higher excited states of the singlet manifold. At the highest irradiance studied, on the other hand, reduced efficiency of photosensitization is attributed to increased photodegradation of doxycycline from higher excited states by processes such as photoionization. A model consistent with these observations is presented along with calculations, based on simple rate equations, that fit the essentials of the proposed model.

  19. Interglacial Durations

    Science.gov (United States)

    Mangili, Clara; McManus, Jerry F.; Raynaud, Dominique

    2014-05-01

    In the context of future global warming induced by human activities, it is essential to assess the role of natural climatic variations. Precise knowledge of the duration of past interglacial periods is fundamental to the understanding of the potential future evolution of the Holocene. Past ice age cycles provide a natural laboratory for exploring the progression and duration of interglacial climate. Palaeorecords from ice, land and oceans extend over the last 800 ka, revealing eight glacial-interglacial cycles, with a range of insolation and greenhouse gas influences. The interglacials display a correspondingly large variety of intensity and duration, thus providing an opportunity for major insights into the mechanisms involved in the behaviour of interglacial climates. A comparison of the duration of these interglacials, however, is often difficult, as the definition of an interglacial depends on the archive that is considered. Therefore, to compare interglacial length and climate conditions from different archives, a consistent definition of interglacial conditions is required, ideally one that is not bound to the method nor to the archive under consideration. Here we present a method to identify interglacials and to calculate their length by mean of a simple statistical approach. We based our method on ~ 400 ka windows of time to determine mean climatic conditions while allowing for the possibility of long term evolution of the climatic baseline. For our study of interglacials of the past 800 ka, we used two windows that largely align with the pre- (800-430 ka ago) and post- (430-0 ka ago) mid-Brunhes event (MBE), although the resulting conclusions are not sensitive to this particular division. We applied this method to the last 800 ka of a few palaeoclimate records: the deuterium ice core (EDC) record as a climatic proxy, the benthic δ18O stack (LR04) as a proxy for sea level/ice volume, ice core (Vostok, EDC) atmospheric CO2 and additional records. Although

  20. Ultrafast Manipulation of Magnetic Order with Electrical Pulses

    Science.gov (United States)

    Yang, Yang

    During the last 30 years spintronics has been a very rapidly expanding field leading to lots of new interesting physics and applications. As with most technology-oriented fields, spintronics strives to control devices with very low energy consumption and high speed. The combination of spin and electronics inherent to spintronics directly tackles energy efficiency, due to the non-volatility of magnetism. However, speed of operation of spintronic devices is still rather limited ( nanoseconds), due to slow magnetization precessional frequencies. Ultrafast magnetism (or opto-magnetism) is a relatively new field that has been very active in the last 20 years. The main idea is that intense femtosecond laser pulses can be used in order to manipulate the magnetization at very fast time-scales ( 100 femtoseconds). However, the use of femtosecond lasers poses great application challenges such as diffraction limited optical spot sizes which hinders device density, and bulky and expensive integration of femtosecond lasers into devices. In this thesis, our efforts to combine ultrafast magnetism and spintronics are presented. First, we show that the magnetization of ferrimagnetic GdFeCo films can be switched by picosecond electronic heat current pulses. This result shows that a non-thermal distribution of electrons directly excited by laser is not necessary for inducing ultrafast magnetic dynamics. Then, we fabricate photoconductive switch devices on a LT-GaAs substrate, to generate picosecond electrical pulses. Intense electrical pulses with 10ps (FWHM) duration and peak current up to 3A can be generated and delivered into magnetic films. Distinct magnetic dynamics in CoPt films are found between direct optical heating and electrical heating. More importantly, by delivering picosecond electrical pulses into GdFeCo films, we are able to deterministically reverse the magnetization of GdFeCo within 10ps. This is more than one order of magnitude faster than any other electrically

  1. Superluminal optical pulse propagation at 1.5 microm in periodic fiber Bragg gratings.

    Science.gov (United States)

    Longhi, S; Marano, M; Laporta, P; Belmonte, M

    2001-11-01

    We report on the experimental observation of superluminal tunneling of picosecond optical pulses in a periodic fiber Bragg grating. Optical pulses of 380-ps duration, generated by an externally-modulated single-frequency erbium-ytterbium laser operating near 1.5-microm wavelength, were propagated at a group velocity greater than approximately 1.97 times the speed of light in vacuum across a 2-cm long fiber grating. Owing to the very large ratio between the thickness of the barrier (2 cm) and the wavelength of probing optical pulses ( approximately 1.5 microm), our experiment allows for the observation of superluminal tunneling in the optical region by direct optoelectronic time-domain measurements.

  2. Terahertz pulse shaping through propagation in a gas of symmetric top molecules

    Science.gov (United States)

    Hamraoui, K.; Babilotte, P.; Billard, F.; Hertz, E.; Faucher, O.; Coudert, L. H.; Sugny, D.; Lavorel, B.

    2017-10-01

    Symmetric top molecules of methyl iodide are irradiated with a terahertz pulse generated by a two-color plasma and shaped by a short propagation in air. Free-induction decay is emitted by the excited molecular sample and then propagates in air before detection. The experimental data show that the input terahertz (THz) pulse undergoes strong reshaping through absorption and dispersion. This leads to narrow wave packets at revival times due to the excitation of high rotational energy levels. Typically, a THz burst of duration ≃15 -20 ps is produced periodically, with a central frequency of ≃1 THz and a width that can be as narrow as 60-80 GHz. Pulse shaping based on propagation can be useful for quantum control in molecules. We provide a theoretical description of this wave propagation based on the Maxwell-Bloch equation. The observed experimental signal is in good agreement with the numerical simulations.

  3. EDH 'Millionaire' in PS Division

    CERN Document Server

    2001-01-01

    Christmas cheer! Left to right: Gerard Lobeau receives a bottle of Champagne from Derek Mathieson and Jurgen De Jonghe in recognition of EDH's millionth document. At 14:33 on Monday 3 December a technician in PS division, Gerard Lobeau, unwittingly became part of an important event in the life of CERN's Electronic Document Handling system (EDH). While ordering some pieces of aluminum for one of the PS's 10Mhz RF cavities, he created EDH document number 1,000,000. To celebrate the event Derek Mathieson (EDH Project Leader) and Jurgen De Jonghe (Original EDH Project Leader) presented Mr Lobeau with a bottle of champagne. As with 93% of material requests, Mr Lobeau's order was delivered within 24 hours. 'I usually never win anything' said Mr Lobeau as he accepted his prize, 'I initially though there may have been a problem with EDH when the document number had so many zeros in it, and was then surprised to get a phone call from you a few minutes later.' The EDH team had been monitoring the EDH document number ...

  4. Burst train generator of high energy femtosecond laser pulses for driving heat accumulation effect during micromachining.

    Science.gov (United States)

    Rezaei, Saeid; Li, Jianzhao; Herman, Peter R

    2015-05-01

    A new method for generating high-repetition-rate (12.7-38.2 MHz) burst trains of femtosecond laser pulses has been demonstrated for the purpose of tailoring ultrashort laser interactions in material processing that can harness the heat accumulation effect among pulses separated by a short interval (i.e., 26 ns). Computer-controlled time delays were applied to synchronously trigger the high frequency switching of a high voltage Pockels cell to specify distinctive values of polarization rotation for each round-trip of a laser pulse cycling within a passive resonator. Polarization dependent output coupling facilitated the flexible shaping of the burst envelope profile to provide burst trains of up to ∼1  mJ of burst energy divided over a selectable number (1 to 25) of pulses. Individual pulses of variable energy up to 150 μJ and with pulse duration tunable over 70 fs to 2 ps, were applied in burst trains to generate deep and high aspect ratio holes that could not form with low-repetition-rate laser pulses.

  5. Measurements of plasma mirror reflectivity and focal spot quality for tens of picosecond laser pulses

    Science.gov (United States)

    Forestier-Colleoni, Pierre; Williams, Jackson; Scott, Graeme; Mariscal, Dereck. A.; McGuffey, Christopher; Beg, Farhat N.; Chen, Hui; Neely, David; Ma, Tammy

    2017-10-01

    The Advanced Radiographic Capability (ARC) laser at the NIF (LLNL) is high-energy ( 4 kJ) with a pulse length of 30ps, and is capable of focusing to an intensity of 1018W/cm2 with a 100 μm focal spot. The ARC laser is at an intensity which can be used to produce proton beams. However, for applications such as radiography and warm dense matter creation, a higher laser intensity may be desired to generate more energetic proton beams. One possibility to increase the intensity is to decrease the focused spot size by employing a smaller f-number optic. But it is difficult to implement such an optic or to bring the final focusing parabola closer to the target within the complicated NIF chamber geometry. A proposal is to use ellipsoidal plasma mirrors (PM) for fast focusing of the ARC laser light, thereby increasing the peak intensity. There is uncertainty, however, in the survivability and reflectivity of PM at such long pulse durations. Here, we show experimental results from the Titan laser to study the reflectivity of flat PM as a function of laser pulse length. A calorimeter was used to measure the PM reflectivity. We also observed degradation of the far and near field energy distribution of the laser after the reflection by the PM for pulse-lengths beyond 10ps. Contract DE-AC52-07NA27344. Funded by the LLNL LDRD program: tracking code 17-ERD-039.

  6. Comparison of different processes for separation of glass and crystals using ultrashort pulsed lasers

    Science.gov (United States)

    Kumkar, M.; Bauer, L.; Russ, S.; Wendel, M.; Kleiner, J.; Grossmann, D.; Bergner, K.; Nolte, S.

    2014-03-01

    We investigate cutting of transparent materials using ultra short laser pulses with pulse durations in the sub to a few ps regime. All compared methods base on nonlinear absorption including ablation cutting and cleaving or selective etching supported by laser induced modification inside the bulk material. For most of the experiments samples of hardened glass (Corning Gorilla®) with thickness up to 700 μm were used, ablation cutting of sapphire is presented additionally. Absorption and modification inside the volume is analyzed in detail, aiming for tailored modifications. Besides optical microscopy a pump probe setup was used. We show results of time resolved absorption measurements of 6 ps pulses focused into the volume. We observe shielding due to the interaction region and accumulation effects influencing the modifications. First results on inscribing and cutting by using beam shaping indicate the importance of tailoring the shape and arrangement of the pulses temporally and spatially. The results presented for the different cutting methods supports an assessment of the individual potential and a selection of the applicable method based on the requirements.

  7. Sub-nanosecond resolution electric field measurements during ns pulse breakdown in ambient air

    Science.gov (United States)

    Simeni Simeni, Marien; Goldberg, Ben; Gulko, Ilya; Frederickson, Kraig; Adamovich, Igor V.

    2018-01-01

    Electric field during ns pulse discharge breakdown in ambient air has been measured by ps four-wave mixing, with temporal resolution of 0.2 ns. The measurements have been performed in a diffuse plasma generated in a dielectric barrier discharge, in plane-to-plane geometry. Absolute calibration of the electric field in the plasma is provided by the Laplacian field measured before breakdown. Sub-nanosecond time resolution is obtained by using a 150 ps duration laser pulse, as well as by monitoring the timing of individual laser shots relative to the voltage pulse, and post-processing four-wave mixing signal waveforms saved for each laser shot, placing them in the appropriate ‘time bins’. The experimental data are compared with the analytic solution for time-resolved electric field in the plasma during pulse breakdown, showing good agreement on ns time scale. Qualitative interpretation of the data illustrates the effects of charge separation, charge accumulation/neutralization on the dielectric surfaces, electron attachment, and secondary breakdown. Comparison of the present data with more advanced kinetic modeling is expected to provide additional quantitative insight into air plasma kinetics on ~ 0.1–100 ns scales.

  8. Picosecond pulses of coherent MM-wave radiation in a photoinjector-driven waveguide free-selected laser

    Energy Technology Data Exchange (ETDEWEB)

    Fochs, S.N.; Le Sage, G.P.; Feng, L. [Univ. of California, Davis, CA (United States)] [and others

    1995-12-31

    A 5 MeV, high repetition rate (2.142 GHz in burst mode), high brightness, tabletop photoinjector is currently under construction at the UC Davis Department of Applied Science, on the LLNL site. Ultrashort pulses of coherent synchrotron radiation can be generated by transversally accelerating the electron beam with a wiggler in either metallic or dielectric-loaded waveguide FEL structures. This interaction is investigated theoretically and experimentally. Subpicosecond photoelectron bunches will be produced in the photoinjector by irradiating a high quantum efficiency Cs{sub 2}Te (Cesium Telluride) photocathode with a train of 100 UV (210 nm), ultra-short (250 fs) laser pulses. These bunches will be accelerated in a 1-1/2 cell {pi}-mode X-band RF gun e energized by a 20 MW, 8,568 GHz SLAC klystron. The peak current is 0.25 kA (0.25 nC, 1 ps), with a normalized beam emittance {epsilon}{sub n}<2.5 {pi} mm-mrad. This prebunched electron beam is then transversally accelerated in a cylindrical waveguide by a 30-mm period, 10 period long helical wiggler. The peak wiggler field is adjusted to 8.5 kG, so that the group velocity of the radiated electromagnetic waves matches the axial velocity of the electron bunch (grazing condition, zero slippage). Chirped output pulses in excess of 2 MW power are predicted, with an instantaneous bandwidth extending from 125 GHz to 225 GHz and a pulse duration of 15 ps (HWHM). To produce even shorter pulses, a dielectric-loaded waveguide can be used. The dispersion relation of this waveguide structure has an inflection point (zero group velocity dispersion). If the grazing condition is satisfied at this point, the final output pulse duration is no longer determined by slippage, or by group velocity dispersion and bandwidth, but by higher-order dispersive effects yielding transform-limited pulses.

  9. Structural transformations in silicon under exposure by femtosecond laser pulse: role of electron-hole plasma and phonon-phonon anharmonism

    CERN Document Server

    Kudryashov, S I

    2002-01-01

    It is experimentally shown for the first time that by the effect of the feed-up laser pulse of 100 fs duration on the silicon target the consecutive structural transitions of the substance into the new crystalline and liquid metallic phase occur both during the laser pulse feed-up and after 0.1-10 sup 3 ps, depending on the material excitation conditions. The thresholds of the observed structural transitions are determined and the phonon nodes, responsible for therefore, are identified. The structural transitions dynamics in the silicon by the 01.-10 sup 3 ps times is described within the frames of the model of the phonon modes instability, originating due to the plasma electron-hole effect and also due to the intra- and intermode phonon-phonon anharmonic interactions

  10. Non-Pulse-Leakage 100-kHz Level, High Beam Quality Industrial Grade Nd:YVO4 Picosecond Amplifier

    Directory of Open Access Journals (Sweden)

    Zhenao Bai

    2017-06-01

    Full Text Available A non-pulse-leakage optical fiber pumped 100-kHz level high beam quality Nd:YVO4 picosecond amplifier has been developed. An 80 MHz, 11.5 ps mode-locked picosecond laser is used as the seed with single pulse energy of 1 nJ. By harnessing the double β-BaB2O4 (BBO crystal Pockels cells in both the pulse picker and regenerative amplifier, the seed pulse leakage of the output is suppressed effectively with an adjustable repetition rate from 200 to 500 kHz. Through one stage traveling-wave amplifier, a maximum output power of 24.5 W is generated corresponding to the injected regenerative amplified power of 9.73 W at 500 kHz. The output pulse duration is 16.9 ps, and the beam quality factor M2 is measured to be 1.25 with near-field roundness higher than 99% at the full output power.

  11. Picosecond and subpicosecond pulsed laser deposition of Pb thin films

    Directory of Open Access Journals (Sweden)

    F. Gontad

    2013-09-01

    Full Text Available Pb thin films were deposited on Nb substrates by means of pulsed laser deposition (PLD with UV radiation (248 nm, in two different ablation regimes: picosecond (5 ps and subpicosecond (0.5 ps. Granular films with grain size on the micron scale have been obtained, with no evidence of large droplet formation. All films presented a polycrystalline character with preferential orientation along the (111 crystalline planes. A maximum quantum efficiency (QE of 7.3×10^{-5} (at 266 nm and 7 ns pulse duration was measured, after laser cleaning, demonstrating good photoemission performance for Pb thin films deposited by ultrashort PLD. Moreover, Pb thin film photocathodes have maintained their QE for days, providing excellent chemical stability and durability. These results suggest that Pb thin films deposited on Nb by ultrashort PLD are a noteworthy alternative for the fabrication of photocathodes for superconductive radio-frequency electron guns. Finally, a comparison with the characteristics of Pb films prepared by ns PLD is illustrated and discussed.

  12. The PS200 catching trap: A new tool for ultralow-energy antiproton physics

    Energy Technology Data Exchange (ETDEWEB)

    Holzscheiter, M.H.; Dyer, P.L.; King, N.S.P.; Lizon, D.C.; Morgan, G.L.; Schecker, J.A. (Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)); Hoibraten, S. (University of Colorado, Boulder, Colorado 80309 (United States)); Lewis, R.A.; Otto, T. (Pennsylvania State University, Osmond Laboratory, University Park, Pennsylvania 16802 (United States)); Rochet, J. (CERN, Division PPE, CH 1211 Geneva (Switzerland)); Schauer, M.M. (Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States) Pennsylvania State University, Osmond Laboratory, University Park, Pennsylvania 16802 (United States))

    1994-10-01

    Approximately one million antiprotons have been trapped and electron cooled in the PS200 catching trap from a single fast extracted pulse from LEAR. The system is described in detail, different extraction schemes are discussed, and possible applications of this instrument to ultralow-energy atomic and nuclear physics with antiprotons are mentioned. [copyright] 1994 MAIK/Interperiodika

  13. The PS 200 catching trap: A new tool for ultra-low energy antiproton physics

    Energy Technology Data Exchange (ETDEWEB)

    Holzscheiter, M.H.; Dyer, P.L.; King, N.S.P.; Lizon, D.C.; Morgan, G.L.; Schauer, M.M.; Schecker, J.A. [Los Alamos National Lab., NM (United States); Hoibraten, S. [Colorado Univ., Boulder, CO (United States); Lewis, R.A.; Otto, T. [Pennsylvania State Univ., University Park, PA (United States). Noise Control Lab.; Rochet, J. [CERN, Div. PPE, Geneva (Switzerland)

    1994-04-01

    Approximately one million antiprotons have been trapped and electron cooled in the PS200 catching trap from a single fast extracted pulse from LEAR. The system is described in detail, different extraction schemes are discussed, and possible applications of this instrument to ultra-low energy atomic and nuclear physics with antiprotons are mentioned.

  14. A recoil detector for the Internal Target Facility of AmPS (NIKHEF).

    NARCIS (Netherlands)

    van Sambeek, M.J.M.; Blok, H.P.

    1997-01-01

    A recoil detector has been built for internal target experiments with the Amsterdam Pulse Stretcher and storage ring, AmPS, of NIKHEF. The detector was designed to detect low-energy (1-20 MeV/nucleon) and low-mass (A ≤ 4) recoiling nuclei emerging from electron-induced reactions. The detector

  15. A recoil detector for the internal target facility of AmPS (NIKHEF).

    NARCIS (Netherlands)

    van Sambeek, M.J.M.; Blok, H.P.; Dodge, G.E.; Heimberg, P.C.; Steenbakkers, M.F.M.

    1998-01-01

    A recoil detector has been built for internal target experiments with the Amsterdam Pulse Stretcher and storage ring, AmPS, of NIKHEF. The detector was designed to detect low-energy (1-20 MeV/nucleon) and low-mass (A ≤ 4) recoiling nuclei emerging from electron-induced reactions. The detector

  16. 100J Pulsed Laser Shock Driver for Dynamic Compression Research

    Science.gov (United States)

    Wang, X.; Sethian, J.; Bromage, J.; Fochs, S.; Broege, D.; Zuegel, J.; Roides, R.; Cuffney, R.; Brent, G.; Zweiback, J.; Currier, Z.; D'Amico, K.; Hawreliak, J.; Zhang, J.; Rigg, P. A.; Gupta, Y. M.

    2017-06-01

    Logos Technologies and the Laboratory for Laser Energetics (LLE, University of Rochester) - in partnership with Washington State University - have designed, built and deployed a one of a kind 100J pulsed UV (351 nm) laser system to perform real-time, x-ray diffraction and imaging experiments in laser-driven compression experiments at the Dynamic Compression Sector (DCS) at the Advanced Photon Source, Argonne National Laboratory. The laser complements the other dynamic compression drivers at DCS. The laser system features beam smoothing for 2-d spatially uniform loading of samples and four, highly reproducible, temporal profiles (total pulse duration: 5-15 ns) to accommodate a wide variety of scientific needs. Other pulse shapes can be achieved as the experimental needs evolve. Timing of the laser pulse is highly precise (<200 ps) to allow accurate synchronization of the x-rays with the dynamic compression event. Details of the laser system, its operating parameters, and representative results will be presented. Work supported by DOE/NNSA.

  17. Validity and reliability of the Dutch adaptation of the Psoriatic Arthritis Quality of Life (PsAQoL Questionnaire.

    Directory of Open Access Journals (Sweden)

    Freke Wink

    Full Text Available OBJECTIVE: The Psoriatic Arthritis Quality of Life (PsAQoL questionnaire is a disease- specific instrument developed to measure quality of life (QoL in patients with psoriatic arthritis (PsA. The aim of this study was to translate the measure into Dutch and to determine its psychometric properties. METHOD: Translation of the original English PsAQoL into Dutch was performed by bilingual and lay panel. Ten field-test interviews with PsA patients were performed to assess face and content validity. In total, 211 PsA patients were included in a test-retest postal survey to investigate the reliability and construct validity of the Dutch adaptation of the PsAQoL. The PsAQoL, Health Assessment Questionnaire (HAQ and Skindex-17 were administered on two different occasions approximately two weeks apart. RESULTS: The Dutch version of the PsAQoL was found to be relevant, understandable and easy to complete in only a few minutes. It correlated as expected with the HAQ (Spearman's ρ = 0.72 and the 2 subscales of the Skindex-17 (ρ = 0.40 for the psychosocial and ρ = 0.46 for the symptom scale. Furthermore, the measure had good internal consistency (Cronbach's α = 0.92 and test-retest reliability (ρ = 0.89. The PsAQoL was able to define groups of patients based on self-reported general health status, self-reported severity of PsA and flare of arthritis. Duration of PsA did not influence PsAQoL scores. CONCLUSIONS: The Dutch version of the PsAQoL is a valid and reliable questionnaire suitable for use in clinical or research settings to asses PsA-specific QoL.

  18. Generation of soliton and bound soliton pulses in mode-locked erbium-doped fiber laser using graphene film as saturable absorber

    Science.gov (United States)

    Haris, H.; Harun, S. W.; Anyi, C. L.; Muhammad, A. R.; Ahmad, F.; Tan, S. J.; Nor, R. M.; Zulkepely, N. R.; Ali, N. M.; Arof, H.

    2016-04-01

    We report an observation of soliton and bound-state soliton in passive mode-locked fibre laser employing graphene film as a passive saturable absorber (SA). The SA was fabricated from the graphene flakes, which were obtained from electrochemical exfoliation process. The graphene flakes was mixed with polyethylene oxide solution to form a polymer composite, which was then dried at room temperature to produce a film. The film was then integrated in a laser cavity by attaching it to the end of a fibre ferrule with the aid of index matching gel. The fibre laser generated soliton pulses with a 20.7 MHz repetition rate, 0.88 ps pulse width, 0.0158 mW average output power, 0.175 pJ pulse energy and 18.72 W peak power at the wavelength of 1564 nm. A bound soliton with pulse duration of ~1.04 ps was also obtained at the pump power of 110.85 mW by carefully adjusting the polarization of the oscillating laser. The formation of bound soliton is due to the direct pulse to pulse interaction. The results show that the proposed graphene-based SA offers a simple and cost efficient approach of generating soliton and bound soliton in mode-locked EDFL set-up.

  19. Evaluation of enamel surface modification using PS-OCT after laser treatment to increase resistance to demineralization

    Science.gov (United States)

    Kim, Jin Wan; Chan, Kenneth H.; Fried, Daniel

    2016-02-01

    At laser intensities below ablation, carbonated hydroxyapatite in enamel is converted into a purer phase hydroxyapatite with increased acid resistance. Previous studies suggested the possibility of achieving the conversion without surface modification. This study attempts to evaluate the thresholds for the modification without additional changes in physical and optical properties of the enamel. Bovine specimens were irradiated using an RF-excited CO2 laser operating at 9.4-μm with a pulse duration of 26- μs, pulse repetition rates of 100-1000 Hz, with a Gaussian spatial beam profile - 1.4 mm in diameter. After laser treatment, the samples were subjected to acid demineralization for 48 hours to simulate acidic intraoral conditions of a caries attack. The resulting demineralization and erosion were assessed using polarization sensitive OCT (PS-OCT) and 3D digital microscopy. The images from digital microscopy demonstrated a clear delineation between laser protected zones without visual changes and zones with higher levels of demineralization and erosion. Distinct changes in the surface morphology were found within the laser treated area in accordance with the Gaussian spatial beam profile. There was significant protection from the laser in areas that were not visually altered.

  20. Ps-atom scattering at low energies

    CERN Document Server

    Fabrikant, I I

    2015-01-01

    A pseudopotential for positronium-atom interaction, based on electron-atom and positron-atom phase shifts, is constructed, and the phase shifts for Ps-Kr and Ps-Ar scattering are calculated. This approach allows us to extend the Ps-atom cross sections, obtained previously in the impulse approximation [Phys. Rev. Lett. 112, 243201 (2014)], to energies below the Ps ionization threshold. Although experimental data are not available in this low-energy region, our results describe well the tendency of the measured cross sections to drop with decreasing velocity at $v<1$ a.u. Our results show that the effect of the Ps-atom van der Waals interaction is weak compared to the polarization interaction in electron-atom and positron-atom scattering. As a result, the Ps scattering length for both Ar and Kr is positive, and the Ramsauer-Townsend minimum is not observed for Ps scattering from these targets. This makes Ps scattering quite different from electron scattering in the low-energy region, in contrast to the inter...

  1. Enhanced personal protection at the PS

    CERN Multimedia

    Samuel Morier Genoud

    2013-01-01

    Pictures 03, 06, 07 08 : Pierre Ninin, deputy group leader of GS-ASE and responsible for the installation of the new PS complex safety system, in front of a new access control system.Pictures 10, 12 ,13 : View of Building 271, the future control centre of the new PS complex safety system.

  2. PS, SL and LHC Auditoria change names

    CERN Document Server

    2003-01-01

    Following the replacement of the PS, SL and LHC Divisions by the AB and AT Divisions, the Auditoria are also changing their names. PS Auditorium is renamed AB Meyrin SL Auditorium is renamed AB Prévessin LHC Auditorium is renamed AT

  3. Autocorrelation measurement of fast electron pulses emitted through the interaction of femtosecond laser pulses with a solid target.

    Science.gov (United States)

    Inoue, Shunsuke; Tokita, Shigeki; Otani, Kazuto; Hashida, Masaki; Hata, Masayasu; Sakagami, Hitoshi; Taguchi, Toshihiro; Sakabe, Shuji

    2012-11-02

    We report the first direct measurement of the emission duration of laser-accelerated fast electrons from the surface of a solid target irradiated by a high-intensity femtosecond laser pulse. The emission duration is determined by autocorrelation measurement using the Coulomb repulsive forces that act on two equivalent electron pulses. The emission duration depends on the laser pulse duration for laser pulses of 200-690 fs. Numerical modeling of three-dimensional charged particle dynamics indicates that the emission duration of fast electrons is almost equal to the duration of the laser pulse.

  4. Effect of thermal loading due to laser pulse on thermoelastic porous medium under G-N theory

    Directory of Open Access Journals (Sweden)

    Mohamed I.A. Othman

    Full Text Available The aim of this paper is to study the wave propagation of generalized thermoelastic medium with voids under the effect of thermal loading due to laser pulse with energy dissipation. The material is a homogeneous isotropic elastic half-space and heated by a non-Gaussian laser beam with the pulse duration of 0.2 ps. A normal mode method is proposed to analyse the problem and obtain numerical solutions for the displacement components, stresses, temperature distribution and the change in the volume fraction field. The results of the physical quantities have been illustrated graphically by comparison between both types II and III of Green-Naghdi theory for two values of time, as well as with and without void parameters. Keywords: Laser pulse, Voids, Energy dissipation, Green-Naghdi theory, Wave propagation, Thermoelasticity

  5. Interaction of soft x-ray laser pulse radiation with aluminum surface: Nano-meter size surface modification

    Energy Technology Data Exchange (ETDEWEB)

    Ishino, Masahiko; Faenov, Anatoly; Tanaka, Momoko; Hasegawa, Noboru; Nishikino, Masaharu; Tamotsu, Satoshi; Pikuz, Tatiana; Inogamov, Nail; Zhakhovsky, Vasily; Skobelev, Igor; Fortov, Vladimir; Khohlov, Viktor; Shepelev, Vadim; Ohba, Toshiyuki; Kaihori, Takeshi; Ochi, Yoshihiro; Imazono, Takashi; Kawachi, Tetsuya [Quantum Beam Science Directorate, Japan Atomic Energy Agency, Kyoto 619-0215 (Japan); Joint Institute for High Temperatures, Russian Academy of Science, Moscow 125412 (Russian Federation); Graduate School of Humanities and Science, Nara Women' s University, Nara 630-8506 (Japan); Landau Institute for Theoretical Physics, Russian Academy of Science, Chernogolovka 142432 (Russian Federation); Institute for Computer Aided Design, Russian Academy of Science, Moscow 123056 (Russian Federation)

    2012-07-11

    Interaction of soft x-ray laser radiation with material and caused modification of the exposed surface has both physical and practical interests. We irradiated the focusing soft x-ray laser (SXRL) pulses having a wavelength of 13.9 nm and the duration of 7 ps to aluminum (Al) surface. After the SXRL irradiation process, the irradiated Al surface was observed with a scanning electron microscope. The surface modifications caused by SXRL single pulse exposure were clearly seen. In addition, it was found that the conical structures having around 100 nm in diameters were formed in the shallow features. The nano-meter size modified structures at Al surface induced by SXRL pulse is interesting as the newly surface structure. Hence, the SXRL beam would be a candidate for a tool of micromachining. We also provide a thermomechanical modeling of SXRL interaction with Al briefly to explain the surface modification.

  6. Pulse shaping using the optical Fourier transform technique - for ultra-high-speed signal processing

    DEFF Research Database (Denmark)

    Palushani, Evarist; Oxenløwe, Leif Katsuo; Galili, Michael

    2009-01-01

    This paper reports on the generation of a 1.6 ps FWHM flat-top pulse using the optical Fourier transform technique. The pulse is validated in a 320 Gbit/s demultiplexing experiment.......This paper reports on the generation of a 1.6 ps FWHM flat-top pulse using the optical Fourier transform technique. The pulse is validated in a 320 Gbit/s demultiplexing experiment....

  7. The Boersch effect in a picosecond pulsed electron beam emitted from a semiconductor photocathode

    Energy Technology Data Exchange (ETDEWEB)

    Kuwahara, Makoto, E-mail: kuwahara@imass.nagoya-u.ac.jp; Ujihara, Toru; Saitoh, Koh [Institute of Materials and Systems for Sustainability, Nagoya University, Nagoya 464-8603 (Japan); Graduate School of Engineering, Nagoya University, Nagoya 464-8603 (Japan); Nambo, Yoshito; Aoki, Kota; Sameshima, Kensuke; Asano, Hidefumi [Graduate School of Engineering, Nagoya University, Nagoya 464-8603 (Japan); Jin, Xiuguang [High Energy Accelerator Research Organization (KEK), Tsukuba 305-0801 (Japan); Takeda, Yoshikazu [Aichi Synchrotron Radiation Center, Seto 489-0965 (Japan); Nagoya Industrial Science Research Institute, Nagoya 460-0008 (Japan); Tanaka, Nobuo [Institute of Materials and Systems for Sustainability, Nagoya University, Nagoya 464-8603 (Japan)

    2016-07-04

    The space charge effect has been clearly observed in the energy distributions of picosecond pulse beams from a spin-polarized electron microscope, and was found to depend upon the quantity of charge per pulse. The non-linear phenomena associated with this effect have also been replicated in beam simulations that take into account of a three-dimensional space charge. The results show that a charge of 500 aC/pulse provides the highest brightness with a 16-ps pulse duration, a 30-keV beam energy, and an emission spot of 1.8 μm. Furthermore, the degeneracy of the wave packet of the pulsed electron beam has been evaluated to be 1.6 × 10{sup −5} with a charge of 100 aC/pulse, which is higher than that for a continuously emitted electron beam despite the low beam energy of 30 keV. The high degeneracy and high brightness contribute to the realization of high temporal and energy resolutions in low-voltage electron microscopy, which will serve to reduce radiolysis damage and enhance scattering contrast.

  8. SHORT PULSE STRETCHER

    Science.gov (United States)

    Branum, D.R.; Cummins, W.F.

    1962-12-01

    >A short pulse stretching circuit capable of stretching a short puise to enable it to be displayed on a relatively slow sweeping oscilloscope is described. Moreover, the duration of the pulse is increased by charging a capacitor through a diode and thereafter discharging the capacitor at such time as is desired. In the circuit the trigger pulse alone passes through a delay line, whereas the main signal passes through the diode only, and results in over-all circuit losses which are proportional to the low losses of the diode only. (AEC)

  9. On the crystallization behavior of syndiotactic-b-atactic polystyrene stereodiblock copolymers, atactic/syndiotactic polystyrene blends, and aPS/sPS blends modified with sPS-b-aPS

    Energy Technology Data Exchange (ETDEWEB)

    Annunziata, Liana, E-mail: liana.annunziatta@univ-rennes1.fr [Organométalliques et Catalyse, UMR 6226 Sciences Chimiques CNRS, Université de Rennes 1, Campus de Beaulieu, F-35042 Rennes Cedex (France); Monasse, Bernard, E-mail: bernard.monasse@mines-paristech.fr [Mines-ParisTech, CEMEF, Centre de Mise en Forme des Matériaux, UMR CNRS 7635, Sophia Antipolis (France); Rizzo, Paola; Guerra, Gaetano [Dipartimento di Chimica e Biologia, Università degli studi di Salerno, Via Ponte don Melillo, I-84084 Fisciano, SA (Italy); Duc, Michel [Total Petrochemicals Research Feluy, Zone Industrielle Feluy C, B-7181 Seneffe (Belgium); Carpentier, Jean-François, E-mail: jean-francois.carpentier@univ-rennes1.fr [Organométalliques et Catalyse, UMR 6226 Sciences Chimiques CNRS, Université de Rennes 1, Campus de Beaulieu, F-35042 Rennes Cedex (France)

    2013-09-16

    Crystallization and morphological features of syndiotactic-b-atactic polystyrene stereodiblock copolymers (sPS-b-aPS), atactic/syndiotactic polystyrene blends (aPS/sPS), and aPS/sPS blends modified with sPS-b-aPS, with different compositions in aPS and sPS, have been investigated using differential scanning calorimetry (DSC), polarized light optical microscopy (POM) and wide angle X-ray diffraction (WAXRD) techniques. For comparative purposes, the properties of parent pristine sPS samples were also studied. WAXRD analyses revealed for all the samples, independently from their composition (aPS/sPS ratio) and structure (blends, block copolymers, blends modified with block copolymers), the same polymorphic β form of sPS. The molecular weight of aPS and sPS showed opposite effects on the crystallization of 50:50 aPS/sPS blends: the lower the molecular weight of aPS, the slower the crystallization while the lower the molecular weight of sPS, the faster the crystallization. DSC studies performed under both isothermal and non-isothermal conditions, independently confirmed by POM studies, led to a clear trend for the crystallization rate at a given sPS/aPS ratio (ca. 50:50 and 20:80): sPS homopolymers > sPS-b-aPS block copolymers ∼sPS/aPS blends modified with sPS-b-aPS copolymers > sPS/aPS blends. Interestingly, sPS-b-aPS block copolymers not only crystallized faster than blends, but also affected positively the crystallization behavior of blends. At 50:50 sPS/aPS ratio, blends (Blend-2), block copolymers (Cop-1) and blends modified with block copolymers (Blend-2-mod) crystallized via spherulitic crystalline growth controlled by an interfacial process. In all cases, an instantaneous nucleation was observed. The density of nuclei in block copolymers (160,000−190,000 nuclei mm{sup −3}) was always higher than that in blends and modified blends (30,000−60,000 nuclei mm{sup −3}), even for quite different sPS/aPS ratio. At 20:80 sPS/aPS ratio, the block copolymers

  10. Electron pulse shaping in the FELIX RF accelerator

    CERN Document Server

    Weits, H H; Oepts, D; Van der Meer, Alex F G

    1999-01-01

    The FELIX free-electron laser uses short pulses of relativistic electrons produced by an RF accelerator. The design target for the duration of these electron bunches was around 3 ps. In experiments we observed that the bunches emit coherently enhanced spontaneous emission (CSE) when they travel through an undulator. It was demonstrated that the power level of the CSE critically depends on the settings of the accelerator. In this article we seek to explain these observations by studying the length and shape of the electron bunches as a function of the settings of the accelerator. A particle- tracking model was used to simulate the acceleration and transport processes. These include bunch compression in a 14-cell travelling wave buncher cavity, acceleration in a travelling wave linear accelerator, and passage through a (dispersive) chicane structure. The effect of the phase setting of the RF accelerating field with respect to the arrival time of the electron bunch in each accelerator structure was studied. The ...

  11. 50-mJ macro-pulses at 1064 nm from a diode-pumped picosecond laser system.

    Science.gov (United States)

    Agnesi, A; Carrà, L; Dallocchio, P; Pirzio, F; Reali, G; Lodo, S; Piccinno, G

    2011-10-10

    Pulse-picking from a 100-mW cw mode-locked seeder, a hybrid master-oscillator power-amplifier (MOPA) system, based on Nd:YVO4 and Nd:YAG amplifier modules, has been developed, delivering single-pulses of 8.6 ps at 455-MHz repetition-rate, bunched into ~1-μs trains of 50 mJ ("macro-pulses"). The output beam is linearly polarized and nearly diffraction limited up to the maximum macro-pulse repetition-rate of 50 Hz. The single-pulse peak power and the macro-pulse duration and energy are quite suitable for high-energy nonlinear optical applications such as low-threshold synchronously-pumped parametric converters in the mid infrared. The impact on the overall efficiency of saturation distortion of the macro-pulse envelope as well as of amplified spontaneous emission (ASE) is considered. The managing of the envelope distortion compensation and of the ASE suppression by means of fast saturable absorbers is reported.

  12. HV discharge acceleration by sequences of UV laser filaments with visible and near-infrared pulses

    Science.gov (United States)

    Schubert, Elise; Rastegari, Ali; Feng, Chengyong; Mongin, Denis; Kamer, Brian; Kasparian, Jérôme; Wolf, Jean-Pierre; Arissian, Ladan; Diels, Jean-Claude

    2017-12-01

    We investigate the triggering and guiding of DC high-voltage discharges over a distance of 37 cm by filaments produced by ultraviolet (266 nm) laser pulses of 200 ps duration. The latter reduce the breakdown electric field by half and allow up to 80% discharge probability in an electric field of 920 kV m–1. This high efficiency is not further increased by adding nanosecond pulses in the Joule range at 532 and at 1064 nm. However, the latter statistically increases the guiding length, thereby accelerating the discharge by a factor of 2. This effect is due both to photodetachment and to the heating of the plasma channel, that increases the efficiency of avalanche ionization and reduces electron attachment and recombination.

  13. Proton driven acceleration by intense laser pulses irradiating thin hydrogenated targets

    Energy Technology Data Exchange (ETDEWEB)

    Torrisi, L., E-mail: lorenzo.torrisi@unime.it [Dip.to di Fisica, Università di Messina, V.le F.S. D’Alcontres 31, 98166 S. Agata, Messina (Italy); INFN-Laboratori Nazionali del Sud, Via S. Sofia 44, 95123 Catania (Italy); Cutroneo, M.; Cavallaro, S.; Giuffrida, L.; Andò, L.; Cirrone, P. [INFN-Laboratori Nazionali del Sud, Via S. Sofia 44, 95123 Catania (Italy); Bertuccio, G.; Puglisi, D. [Dip.to di Ing. Elettronica e Sci. dell’Informaz., Pol. di Milano,V. Ponzio34, 20133 Milano (Italy); Calcagno, L. [Dip.to di Fisica, Università di Catania, Via S. Sofia 44, 95123 Catania (Italy); Verona, C. [Dip.to di Ing. Meccanica, Univ. Roma “Tor Vergata”, V. del Politecnico 1, Roma (Italy); Picciotto, A. [Fondazione Bruno Kessler–IRST, Via Sommarive 18, 38050 Povo, Trento (Italy); Krasa, J.; Margarone, D.; Velyhan, A.; Laska, L.; Krousky, E.; Pfeiffer, M.; Skala, J.; Ullschmied, J. [Institute of Physics, ASCR, v.v.i., 182 21 Prague 8 (Czech Republic); Wolowski, J. [Institute of Plasma Physics and Laser Microfusion, IPPLM,23 Hery Str. 01-497 Warsaw (Poland); and others

    2013-05-01

    The Asterix iodine laser of the PALS laboratory in Prague, operating at 1315 nm fundamental frequency, 300 ps pulse duration, 600 J maximum pulse energy and 10{sup 16} W/cm{sup 2} intensity, is employed to irradiate thin hydrogenated targets placed in high vacuum. Different metallic and polymeric targets allow to generate multi-energetic and multi-specie ion beams showing peculiar properties. The plasma obtained by the laser irradiation is monitored, in terms of properties of the emitted charge particles, by using time-of-flight techniques and Thomson parabola spectrometer (TPS). A particular attention is given to the proton beam production in terms of the maximum energy, emission yield and angular distribution as a function of the laser energy, focal position (FP), target thickness and composition.

  14. Proton driven acceleration by intense laser pulses irradiating thin hydrogenated targets

    Science.gov (United States)

    Torrisi, L.; Cutroneo, M.; Cavallaro, S.; Giuffrida, L.; Andò, L.; Cirrone, P.; Bertuccio, G.; Puglisi, D.; Calcagno, L.; Verona, C.; Picciotto, A.; Krasa, J.; Margarone, D.; Velyhan, A.; Laska, L.; Krousky, E.; Pfeiffer, M.; Skala, J.; Ullschmied, J.; Wolowski, J.; Badziak, J.; Rosinski, M.; Ryc, L.; Szydlowski, A.

    2013-05-01

    The Asterix iodine laser of the PALS laboratory in Prague, operating at 1315 nm fundamental frequency, 300 ps pulse duration, 600 J maximum pulse energy and 1016 W/cm2 intensity, is employed to irradiate thin hydrogenated targets placed in high vacuum. Different metallic and polymeric targets allow to generate multi-energetic and multi-specie ion beams showing peculiar properties. The plasma obtained by the laser irradiation is monitored, in terms of properties of the emitted charge particles, by using time-of-flight techniques and Thomson parabola spectrometer (TPS). A particular attention is given to the proton beam production in terms of the maximum energy, emission yield and angular distribution as a function of the laser energy, focal position (FP), target thickness and composition.

  15. NANOSCALE STRUCTURES GENERATION WITHIN THE SURFACE LAYER OF METALS WITH SHORT UV LASER PULSES

    Directory of Open Access Journals (Sweden)

    Dmitry S. Ivanov

    2017-01-01

    Full Text Available We have completed modeling of a laser pulse influence on a gold target. We have applied a hybrid atomistic-continuum model to analyze the physical mechanisms responsible for the process of nanostructuring. The model combines the advantages of Molecular Dynamics and Two Temperature Model. We have carried out a direct comparison of the modeling results and experimental data on nano-modification due to a single ps laser pulse at the energy densities significantly exceeding the melting threshold. The experimental data is obtained due to a laser pulse irradiation at the wavelength of 248 nm and duration of 1.6 ps. The mask projection (diffraction grating creates the sinusoidal intensity distribution on a gold surface with periods of 270 nm, 350 nm, and 500 nm. The experimental data and modeling results have demonstrated a good match subject to complex interrelations between a fast material response to the laser excitation, generation of crystal defects, phase transitions and hydrodynamic motion of matter under condition of strong laser-induced non-equilibrium. The performed work confirms the proposed approach as a powerful tool for revealing the physical mechanisms underlying the process of nanostructuring of metal surfaces. Detailed understanding of the dynamics of these processes gives the possibility for designing the topology of functional surfaces on nano- and micro-scales.

  16. XUV generation from the interaction of pico- and nanosecond laser pulses with nanostructured targets

    Science.gov (United States)

    Barte, Ellie Floyd; Lokasani, Ragava; Proska, Jan; Stolcova, Lucie; Maguire, Oisin; Kos, Domagoj; Sheridan, Paul; O'Reilly, Fergal; Sokell, Emma; McCormack, Tom; O'Sullivan, Gerry; Dunne, Padraig; Limpouch, Jiri

    2017-05-01

    Laser-produced plasmas are intense sources of XUV radiation that can be suitable for different applications such as extreme ultraviolet lithography, beyond extreme ultraviolet lithography and water window imaging. In particular, much work has focused on the use of tin plasmas for extreme ultraviolet lithography at 13.5 nm. We have investigated the spectral behavior of the laser produced plasmas formed on closely packed polystyrene microspheres and porous alumina targets covered by a thin tin layer in the spectral region from 2.5 to 16 nm. Nd:YAG lasers delivering pulses of 170 ps (Ekspla SL312P )and 7 ns (Continuum Surelite) duration were focused onto the nanostructured targets coated with tin. The intensity dependence of the recorded spectra was studied; the conversion efficiency (CE) of laser energy into the emission in the 13.5 nm spectral region was estimated. We have observed an increase in CE using high intensity 170 ps Nd:YAG laser pulses as compared with a 7 ns pulse.

  17. Picked FEL Micro Pulse for Nano-Second Interaction with Bio-Molecule

    CERN Document Server

    Suzuki, Sachiko; Ishii, Katsonuri; Kanai, T; Naito, Y

    2004-01-01

    Laser pulse duration is a very important parameter to determine the threshold between thermal and nonthermal effects in laser surgery of biomedical tissue. Free Electron Laser (FEL) at Osaka University, Japan, has a pulse structure in which a macropulse (pulse width : 15μs) consists of equally separated micropulses, whose width and interval are ~5ps and 44.8ns, respectively. Precise control of micropulse train may establish fast optic processes because thermal relaxation time in the tissue is about 1us. A pulse-picking system was designed in order to extract single or a few micropulses from an entire macropulse using an acousto-optic modulator (AOM) in which the light path can be temporally diffracted by an external gate signal. An extracted micropulse train was monitored by a mercury-cadmium-telluride (MCT) photodetector with ~1ns response time and recorded on digital oscilloscope. A single micropulse was extracted as a result of adjusting duration of the RF wave to 50 ns which is nearly equal to the ...

  18. Ps 22 in Gospels’ interpretation of Passion

    Directory of Open Access Journals (Sweden)

    Sylwester Jędrzejewski

    2012-09-01

    Full Text Available Ps 22 is a piece of artistically high poetry, clear images and metaphors, historical and prophetic references. The conviction of biblical scholars that the New Testament writers has recognized in Ps 22 prophetic witness of passion, accompanies the Church from its beginnings. The words of Jesus on the cross, taken from Ps 22: 2, have a character of lamentable re-symbolization of the prayer of Israel. These words establish a theological answer in the form of suitable credo as well. Dramatic question “why?” is connected with a proclamation and identification “My God”. The personal experience of oppression and death is included by Jesus in the history of his nation and in the experience of God. Ps 22 in the Gospels’ passion context becomes a proclamation form of prayer and a very personal, expressed in such dramatic circumstances confession of the faith.

  19. iPS cell-derived cardiogenicity is hindered by sustained integration of reprogramming transgenes.

    Science.gov (United States)

    Martinez-Fernandez, Almudena; Nelson, Timothy J; Reyes, Santiago; Alekseev, Alexey E; Secreto, Frank; Perez-Terzic, Carmen; Beraldi, Rosanna; Sung, Hoon-Ki; Nagy, Andras; Terzic, Andre

    2014-10-01

    Nuclear reprogramming inculcates pluripotent capacity by which de novo tissue differentiation is enabled. Yet, introduction of ectopic reprogramming factors may desynchronize natural developmental schedules. This study aims to evaluate the effect of imposed transgene load on the cardiogenic competency of induced pluripotent stem (iPS) cells. Targeted inclusion and exclusion of reprogramming transgenes (c-MYC, KLF4, OCT4, and SOX2) was achieved using a drug-inducible and removable cassette according to the piggyBac transposon/transposase system. Pulsed transgene overexpression, before iPS cell differentiation, hindered cardiogenic outcomes. Delayed in counterparts with maintained integrated transgenes, transgene removal enabled proficient differentiation of iPS cells into functional cardiac tissue. Transgene-free iPS cells generated reproducible beating activity with robust expression of cardiac α-actinin, connexin 43, myosin light chain 2a, α/β-myosin heavy chain, and troponin I. Although operational excitation-contraction coupling was demonstrable in the presence or absence of transgenes, factor-free derivatives exhibited an expedited maturing phenotype with canonical responsiveness to adrenergic stimulation. A disproportionate stemness load, caused by integrated transgenes, affects the cardiogenic competency of iPS cells. Offload of transgenes in engineered iPS cells ensures integrity of cardiac developmental programs, underscoring the value of nonintegrative nuclear reprogramming for derivation of competent cardiogenic regenerative biologics. © 2014 American Heart Association, Inc.

  20. Yasp for LEIR to PS injection

    CERN Document Server

    Kain, V; Bartosik, H; Huschauer, A; Jacquet, D; Nicosia, D; Pasinelli, S; Wenninger, J

    2017-01-01

    The steering program YASP was introduced in the LEIRinjection as well as the extraction lines in 2016 to correctthe trajectories with well-known model based correctionalgorithms such as MICADO or SVD. In addition a YASPconfiguration was prepared to correct the extraction linetogether with the first turn of the PS. In this way the injectionoscillations can be corrected while keeping the trajectoryreasonable in the PS injection line.

  1. PS overcomes two serious magnet failures

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Two magnets and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators' spring start-up to two weeks. Here we see the PS magnet string awaiting the replacement no. 6 magnet.

  2. Low energy o-Ps-o-Ps elastic scattering using a simple model

    Energy Technology Data Exchange (ETDEWEB)

    Himanshu, Sharma [Veer Kunwar Singh Univ., Dept. of Physics, Bihar (India); Kiran, Kumari [R N College, P. G. Dept. of Physics, Bihar (India); Sumana, Chakraborty [Indian Association for the Cultivation of Science, Dept. of Theoretical Physics (India)

    2009-06-15

    A simple model is employed to investigate o-Ps-o-Ps (positronium-positronium) scattering at low energies. This model contains the effect of exchange explicitly and a model long range potential in the framework of static-exchange model. These two physical features are of key importance in Ps-Ps (atom-atom) scattering system. S-wave triplet-triplet and singlet-singlet scattering lengths and corresponding phase shifts up to the incident momentum k = 0.5 a.u. are in excellent agreement with those yielded by most elaborate and theoretically sound predictions. (authors)

  3. Effects of pre-fermentation and pulsed-electric-field treatment of primary sludge in microbial electrochemical cells.

    Science.gov (United States)

    Ki, Dongwon; Parameswaran, Prathap; Popat, Sudeep C; Rittmann, Bruce E; Torres, César I

    2015-11-01

    The aim of this study was to investigate the combination of two technologies - pulsed electric field (PEF) pre-treatment and semi-continuous pre-fermentation of primary sludge (PS) - to produce volatile fatty acids (VFAs) as the electron donor for microbial electrolysis cells (MECs). Pre-fermentation with a 3-day solids retention time (SRT) led to the maximum generation of VFAs, with or without pretreatment of the PS through pulsed-electric-fields (PEF). PEF treatment before fermentation enhanced the accumulation of the preferred VFA, acetate, by 2.6-fold. Correspondingly, MEC anodes fed with centrate from 3-day pre-fermentation of PEF-treated PS had a maximum current density ∼3.1 A/m(2), which was 2.4-fold greater than the control pre-fermented centrate. Over the full duration of batch MEC experiments, using pre-fermented centrate led to successful performance in terms of Coulombic efficiency (95%), Coulombic recovery (80%), and COD-removal efficiency (85%). Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Opto-electronic properties of a TiO{sub 2}/PS/mc-Si heterojunction based solar cell

    Energy Technology Data Exchange (ETDEWEB)

    Janene, N.; Ghrairi, N. [Laboratoire de Photovoltaïque, Centre de Recherches et des Technologies de l’Energie, Technopole de Borj-Cédria, BP 95, 2050 Hammam-Lif (Tunisia); Allagui, A. [Center for Advanced Materials Research, University of Sharjah, PO Box 27272, Sharjah (United Arab Emirates); Dept. of Sustainable and Renewable Energy Engineering, University of Sharjah, PO Box 27272, Sharjah (United Arab Emirates); Alawadhi, H. [Center for Advanced Materials Research, University of Sharjah, PO Box 27272, Sharjah (United Arab Emirates); Khakani, M. A. El [Institut National de la Recherche Scientifique, INRS-Énergie, Matériaux et Télécommunications, 1650, Blvd. Lionel-Boulet, Varennes, QC, Canada J3X-1S2 (Canada); Bessais, B. [Laboratoire de Photovoltaïque, Centre de Recherches et des Technologies de l’Energie, Technopole de Borj-Cédria, BP 95, 2050 Hammam-Lif (Tunisia); Gaidi, M., E-mail: mkaidi@sharjah.ac.ae [Center for Advanced Materials Research, University of Sharjah, PO Box 27272, Sharjah (United Arab Emirates)

    2016-04-15

    Graphical abstract: - Highlights: • In this work solar cells based on Au/PS/mc-Si/Al and Au/TiO{sub 2}/PS/mc-Si/Al structures have prepared. • A novel double treatment passivation based on TiO2/Porous Si has been used. • An enhancement of the electrical properties of TiO{sub 2}/PS/mc-Si heterojunction was observed after TiO{sub 2} coating. • The solar cells efficiencies past from 1.4% for uncoated PS/mc-Si structure to 5% for TiO{sub 2} coated one. - Abstract: In this work, we show the results of our investigation on the photoelectric properties of heterojunction solar cells based on Au/PS/mc-Si/Al and Au/TiO{sub 2}/PS/mc-Si/Al structures. Porous silicon (PS) were prepared by an electrochemical etching process with different values of current density. The surface porosity was found to increase with the increase of current density. Pulsed laser deposition was used to deposit 80 nm TiO{sub 2} thin films. Surface morphology and structural properties of TiO{sub 2}/PS were characterized by using scanning electron microscopy (SEM) and atomic force microscopy (AFM). An enhancement of the electrical properties of the TiO{sub 2}/PS/mc-Si heterojunction was observed after coating with TiO{sub 2}. As a consequence, the solar cell efficiencies increased from 1.4% for the uncoated PS/mc-Si structure to 5% for the TiO{sub 2} coated one. Impedance spectroscopy confirmed the passivation effect of TiO{sub 2} through the improvement of the elaborated cells’ electron lifetime and the formation of a TiO{sub 2}/PS/Au heterojunction with the appearance of a second semi-circle in the Nyquist plot.

  5. An Antiproton Decelerator in the CERN PS Complex

    CERN Document Server

    Riunaud, J P; Baird, S A; Boillot, J; Bosser, Jacques; Brouet, M; Caspers, Friedhelm; Chanel, M; Chohan, V; Eriksson, T; Garoby, R; Giannini, R; Giovannozzi, Massimo; Gruber, J; Hémery, J Y; Koziol, Heribert; MacCaferri, R; Maury, S; Metzmacher, K D; Möhl, D; Mulder, H; Pedersen, F; Perriollat, F; Poncet, Alain; Riunaud, J P; Serre, C; Simon, Daniel Jean; Tranquille, G; Tuyn, Jan Willem Nicolaas; Williams, B; Williams, D J

    1996-01-01

    The present CERN PS low-energy antiproton complex involves 4 machines to collect, cool, decelerate and supply experiments with up to 1010 antiprotons per pulse and per hour of momenta ranging from 0.1 to 2 GeV/c. In view of a possible future physics programme requiring low energy antiprotons, mainly to carry out studies on antihydrogen, a simplified scheme providing at low cost antiprotons at 100 MeV/c has been studied. It requires only one machine, the present Antiproton Collector (AC) converted into a cooler and decelerator (Antiproton Decelerator, AD) and delivering beam to experiments in the hall of the present Antiproton Accumulator Complex (AAC) [1]. This paper describes the feasibility study of such a scheme [2].

  6. First PS magnet unit, with members of the Magnet Group.

    CERN Multimedia

    CERN PhotoLab

    1956-01-01

    Members of the Magnet Group, sitting atop the first unit of the PS combined-function magnet. The picture was taken at the Institute of Physics of Geneva University, as CERN was still a muddy construction site at that time. All these people have now retired, but all of the magnets are still pulsing away. Front row (left to right): R.Tinguely, C.Germain, G.Plass, D.Neet, B.de Raad, M.Cavallaro, K.H.Reich, G.Kuhn, J.Nilsson, C.A.Ramm, Paillard. Second row: L.Resegotti, M.Niklaus, C.J.Zilverschoon, R.Bertolotto, Marcellin, G.Brianti, P.Collet. Standing behind: B.Kuiper.

  7. Small-size meshless 50 ps streak tube

    Science.gov (United States)

    Ageeva, N. V.; Andreev, S. V.; Belolipetski, V. S.; Bryukhnevich, G. I.; Greenfield, D. E.; Ivanova, S. R.; Kaverin, A. M.; Khohlova, A. N.; Kuz'menko, E. A.; Levina, G. P.; Makushina, V. A.; Monastyrskiy, M. A.; Schelev, M. Ya.; Semichastnova, Z. M.; Serdyuchenko, Yu. N.; Skaballanovich, T. A.; Sokolov, V. E.

    2008-11-01

    In contrast to the conventional image intensifier with large work area, a streak image tube should possess additional important feature - the comparatively small temporal distortion at the entire work area of the photocathode. With this additional engineering restriction taken into account, a novel small-size meshless streak image tube has been developed by means of numerical optimization. The tube with 25-mm wide work area contains a pair of deflection plates to sweep the electron image along the 25 mm output phosphor screen that is separated by 100 mm from the photocathode. The electron image can be shuttered with a 300 V blanking electric pulse. Electron-optical magnification of the tube is unit; spatial resolution reaches 30 lp/mm over the entire photocathode work area; temporal resolution lies in the 20 - 50 ps range, depending on the accelerating voltage (6 - 15 kV).

  8. Dynamic control of laser driven proton beams by exploiting self-generated, ultrashort electromagnetic pulses

    Energy Technology Data Exchange (ETDEWEB)

    Kar, S., E-mail: s.kar@qub.ac.uk; Ahmed, H.; Nersisyan, G.; Hanton, F.; Naughton, K.; Lewis, C. L. S.; Borghesi, M. [Centre for Plasma Physics, School of Mathematics and Physics, Queen' s University Belfast, Belfast BT7 1NN (United Kingdom); Brauckmann, S.; Giesecke, A. L.; Willi, O. [Institut für Laser-und Plasmaphysik, Heinrich-Heine-Universität, Düsseldorf (Germany)

    2016-05-15

    As part of the ultrafast charge dynamics initiated by high intensity laser irradiations of solid targets, high amplitude EM pulses propagate away from the interaction point and are transported along any stalks and wires attached to the target. The propagation of these high amplitude pulses along a thin wire connected to a laser irradiated target was diagnosed via the proton radiography technique, measuring a pulse duration of ∼20 ps and a pulse velocity close to the speed of light. The strong electric field associated with the EM pulse can be exploited for controlling dynamically the proton beams produced from a laser-driven source. Chromatic divergence control of broadband laser driven protons (upto 75% reduction in divergence of >5 MeV protons) was obtained by winding the supporting wire around the proton beam axis to create a helical coil structure. In addition to providing focussing and energy selection, the technique has the potential to post-accelerate the transiting protons by the longitudinal component of the curved electric field lines produced by the helical coil lens.

  9. Characterization and compression of dissipative-soliton-resonance pulses in fiber lasers

    Science.gov (United States)

    Li, Daojing; Li, Lei; Zhou, Junyu; Zhao, Luming; Tang, Dingyuan; Shen, Deyuan

    2016-03-01

    We report numerical and experimental studies of dissipative-soliton-resonance (DSR) in a fiber laser with a nonlinear optical loop mirror. The DSR pulse presents temporally a flat-top profile and a clamped peak power. Its spectrum has a rectangle profile with characteristic steep edges. It shows a unique behavior as pulse energy increases: The rectangle part of the spectrum is unchanged while the newly emerging spectrum sits on the center part and forms a peak. Experimental observations match well with the numerical results. Moreover, the detailed evolution of the DSR pulse compression is both numerically and experimentally demonstrated for the first time. An experimentally obtained DSR pulse of 63 ps duration is compressed down to 760 fs, with low-intensity pedestals using a grating pair. Before being compressed to its narrowest width, the pulse firstly evolves into a cat-ear profile, and the corresponding autocorrelation trace shows a crown shape, which distinguishes itself from properties of other solitons formed in fiber lasers.

  10. Characterization and compression of dissipative-soliton-resonance pulses in fiber lasers

    CERN Document Server

    Li, Daojing; Zhou, Junyu; Zhao, Luming; Tang, Dingyuan; Shen, Deyuan

    2016-01-01

    We report numerical and experimental studies of dissipative-soliton-resonance (DSR) in a fiber laser with a nonlinear optical loop mirror. The DSR pulse presents temporally a flat-top profile and a clamped peak power. Its spectrum has a rectangle profile with characteristic steep edges. It shows a unique behavior as pulse energy increases: The rectangle part of the spectrum is unchanged while the newly emerging spectrum sits on the center part and forms a peak. Experimental observations match well with the numerical results. Moreover, compression of the DSR pulses is both numerically and experimentally demonstrated for the first time. An experimentally obtained DSR pulse of 63 ps duration is compressed down to 760 fs, with low-intensity pedestals using a grating pair. Before being compressed to its narrowest width, the pulse firstly evolves into a cat-ear profile, and the corresponding autocorrelation trace shows a crown shape, which distinguishes itself from properties of other solitons formed in fiber laser...

  11. Generation of trains of ultrashort microwave pulses by two coupled helical gyro-TWTs operating in regimes of amplification and nonlinear absorption

    Science.gov (United States)

    Ginzburg, N. S.; Denisov, G. G.; Vilkov, M. N.; Sergeev, A. S.; Zotova, I. V.; Samsonov, S. V.; Mishakin, S. V.

    2017-02-01

    Based on a time-domain model, we demonstrate that a periodic train of powerful ultrashort microwave pulses can be generated in an electron oscillator consisting of two coupled helically corrugated gyrotron travelling wave tubes (gyro-TWTs) operating in regimes of amplification and saturable absorption, respectively. The mechanism of pulse formation in such an oscillator is based on the effect of passive mode-locking widely used in laser physics. Saturable absorption can be implemented in a gyro-TWT in the Kompfner dip regime by a proper matching of the guiding magnetic field. According to simulations with the parameters of an experimentally realized Ka-band gyro-TWT, the peak power of generated pulses with a duration of 200 ps can achieve 400 kW.

  12. Generation of 70 fs broadband pulses in a hybrid nonlinear amplification system with mode-locked Yb:YAG ceramic oscillator

    Science.gov (United States)

    Liu, Yang; Wang, Chao; Luo, Daping; Yang, Chao; Li, Jiang; Ge, Lin; Pan, Yubai; Li, Wenxue

    2017-12-01

    We demonstrate the passively mode-locked laser performances of bulk Yb:YAG ceramic prepared by non-aqueous tape casting, which generates initial pulses in temporal width of 3 ps and spectrum width of 3 nm without intra-cavity dispersion management. The ceramic laser is further used as seeding oscillator in a fiber nonlinear amplification system, where ultrashort pulses in maximum output power of ∼100 W and pulse duration of 70 fs are achieved. Moreover, the laser spectrum is broadened to be ∼41 nm due to self-phase modulation effects in the gain fiber, overcoming the narrow spectrum limitations of ceramic materials. Our approach opens a new avenue for power-scaling and spectrum-expanding of femtosecond ceramic lasers.

  13. LS1 Report: PS beams are back!

    CERN Multimedia

    Katarina Anthony & Anaïs Schaeffer

    2014-01-01

    For the first time in over 15 months, there are beams back in the PS. Making their first tour of the accelerator today, 20 June, their injection marks the end of weeks of cold checkouts and hardware commissioning in the PS.   The CERN Control Centre (CCC) is back in business: people gather to restart the LHC injectors, today the PS. Since hardware commissioning was wrapped up on 23 May, the Operations Group (BE-OP) has been conducting cold checkouts on the PS. This involves switching on all of the machine's systems, verifying that they respond to commands by OP and ensuring they are calibrated to beam timings. "These verifications were done, in part, during the hardware commissioning dry runs," says Rende Steerenberg, PS section leader. "But the cold checkouts are on a much larger scale, as we act as if there is beam in the whole machine. We placed a full load on the controls system, cooling, networks, etc. in order to setup the accelerator in the most realis...

  14. Synthesis of Nanosecond Ultrawideband Radiation Pulses

    Science.gov (United States)

    Koshelev, V. I.; Plisko, V. V.; Sevostyanov, E. A.

    2017-12-01

    The synthesis of electromagnetic pulses with an extended spectrum by summing pulses of different duration in free space has been studied. The radiation spectrum has been estimated analytically for a 4-element array of combined antennas excited by bipolar voltage pulses of duration 0.5, 1, 2, and 3 ns. It has been shown experimentally that radiation with a spectral width of more than three octaves can be produced using a 2×2 array of combined antennas excited by bipolar pulses of duration 2 and 3 ns.

  15. Generation And Measurement Of High Contrast Ultrashort Intense Laser Pulses

    CERN Document Server

    Konoplev, O A

    2000-01-01

    In this thesis, the generation and measurement of high contrast, intense, ultrashort pulses have been studied. Various factors affecting the contrast and pulse shape of ultrashort light pulses from a chirped pulse amplification (CPA) laser system are identified. The level of contrast resulting from influence of these factors is estimated. Methods for improving and controlling the pulse shape and increasing the contrast are discussed. Ultrahigh contrast, 1-ps pulses were generated from a CPA system with no temporal structure up to eleven orders of magnitude. This is eight orders of magnitude higher contrast than the original pulse. This contrast boost was achieved using two techniques. One is the optical pulse cleaning based on the nonlinear birefringence of the chirping fiber and applied to the pulses before amplification. The other is the fast saturable absorber. The fast saturable absorber was placed after amplification and compression of the pulse. The measurements of high-contrast, ultrashort pulse with h...

  16. Pulse on Pulse

    DEFF Research Database (Denmark)

    Schmidt, Ulrik; Carlson, Merete

    2012-01-01

    of the visitor’s beating heart to the blink of a fragile light bulb, thereby transforming each light bulb into a register of individual life. But at the same time the blinking light bulbs together produce a chaotically flickering light environment composed by various layers of repetitive rhythms, a vibrant...... and pulsating ‘room’. Hence, the visitors in Pulse Room are invited into a complex scenario that continuously oscillates between various aspects of signification (the light bulbs representing individual lives; the pulse itself as the symbolic ‘rhythm of life’) and instants of pure material processuality...... (flickering light bulbs; polyrhythmic layers). Taking our point of departure in a discussion of Gilles Deleuze’s concepts of modulation and signaletic material in relation to electronic media, we examine how the complex orchestration of pulsation between signification and material modulation produces...

  17. Comparison of implosion core metrics: A 10 ps dilation X-ray imager vs a 100 ps gated microchannel plate

    Science.gov (United States)

    Nagel, S. R.; Benedetti, L. R.; Bradley, D. K.; Hilsabeck, T. J.; Izumi, N.; Khan, S.; Kyrala, G. A.; Ma, T.; Pak, A.

    2016-11-01

    The dilation x-ray imager (DIXI) [T. J. Hilsabeck et al., Rev. Sci. Instrum. 81, 10E317 (2010); S. R. Nagel et al., ibid. 83, 10E116 (2012); S. R. Nagel et al., ibid. 85, 11E504 (2014)] is a high-speed x-ray framing camera that uses the pulse-dilation technique to achieve a temporal resolution of less than 10 ps. This is a 10 × improvement over conventional framing cameras currently employed on the National Ignition Facility (NIF) (100 ps resolution), and otherwise only achievable with 1D streaked imaging. A side effect of the dramatically reduced gate width is the comparatively lower detected signal level. Therefore we implement a Poisson noise reduction with non-local principal component analysis method [J. Salmon et al., J. Math. Imaging Vision 48, 279294 (2014)] to improve the robustness of the DIXI data analysis. Here we present results on ignition-relevant experiments at the NIF using DIXI. In particular we focus on establishing that/when DIXI gives reliable shape metrics (P0, P2, and P4 Legendre modes, and their temporal evolution/swings).

  18. Laser and Plasma Parameters for Laser Pulse Amplification by Stimulated Brillouin Backscattering in the Strong Coupling Regime

    Science.gov (United States)

    Gangolf, Thomas; Blecher, Marius; Bolanos, Simon; Lancia, Livia; Marques, Jean-Raphael; Cerchez, Mirela; Prasad, Rajendra; Aurand, Bastian; Loiseau, Pascal; Fuchs, Julien; Willi, Oswald

    2017-10-01

    In the ongoing quest for novel techniques to obtain ever higher laser powers, plasma amplification has drawn much attention, benefiting from the fact that a plasma can sustain much higher energy densities than a solid state amplifier. As a plasma process, Stimulated Brillouin Backscattering in the strong coupling regime (sc-SBS) can be used to transfer energy from one laser pulse (pump) to another (seed), by a nonlinear ion oscillation forced by the pump laser. Here, we report on experimental results on amplification by sc-SBS using the ARCTURUS Ti:Sapphire multi-beam laser system at the University of Duesseldorf, Germany. Counter-propagating in a supersonic Hydrogen gas jet target, an ultrashort seed pulse with a pulse duration between 30 and 160 fs and an energy between 1 and 12 mJ was amplified by a high-energy pump pulse (1.7 ps, 700 mJ). For some of the measurements, the gas was pre-ionized with a separate laser pulse (780 fs, 460 mJ). Preliminary analysis shows that the amplification was larger for the longer seed pulses, consistent with theoretical predictions.

  19. Recent improvements of the RF Beam control for LHC-type beams in the CERN PS

    CERN Document Server

    Damerau, H; Schokker, M

    2010-01-01

    To cope with the large variety of different beams for the LHC, the RF beam control in the CERN PS has evolved continuously to improve its flexibility and reliability. Single-bunch beams, several different multi-bunch beams with 25, 50 or 75 ns bunch spacing at ejection for LHC filling, as well as two lead-ion beam variants are now regularly produced in pulse-to-pulse operation. The multibunch beam control for protons can be easily re-adjusted from 0.25 · 1011 to 1.3 · 1011 particles per ejected bunch. Depending on the number of bunches injected from the PS Booster, the length of the ejected bunch train may vary from 8 to 72 bunches. This paper summarizes recent improvements in the low-level RF systems and gives an outlook on the future consolidation.

  20. PS overcomes two serious magnet failures

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Two magnets and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators' spring start-up to two weeks. These pictures show one of the magnets (no. 19) on the PS locomotive brought back into service for the removal and replacement operations.

  1. Development of a new picosecond pulse radiolysis system by using a femtosecond laser synchronized with a picosecond linac. A step to femtosecond pulse radiolysis

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Yoichi; Yamamoto, Tamotsu; Miki, Miyako; Seki, Shu; Okuda, Shuichi; Honda, Yoshihide; Kimura, Norio; Tagawa, Seiichi [Osaka Univ., Ibaraki (Japan). Inst. of Scientific and Industrial Research; Ushida, Kiminori

    1997-03-01

    A new picosecond pulse radiolysis system by using a Ti sapphire femtosecond laser synchronized with a 20 ps electron pulse from the 38 MeV L-band linac has been developed for the research of the ultra fast reactions in primary processes of radiation chemistry. The timing jitter in the synchronization of the laser pulse with the electron pulse is less than several picosecond. The technique can be used in the next femtosecond pulse radiolysis. (author)

  2. Linear optical methods for temporal characterization of femtosecond UV pulses

    Science.gov (United States)

    Valadan, Mohammadhassan; D'Ambrosio, Davide; Gesuele, Felice; Velotta, Raffaele; Altucci, Carlo

    2014-05-01

    The realization of a first-order interferometric autocorrelator in a nearly collinear geometry is reported as an alternative method to measure the minimum pulse duration of femtosecond deep-UV laser pulses. The Fourier limited duration of 257-nm femtosecond pulses is measured with high accuracy, and compared to what obtained by spectrally measuring the bandwidth of the pulses. The agreement between the two methods is excellent, thus indicating the interferometric autocorrelator as a useful tool to extract the chirp of femtosecond UV pulses when used together with a second-order autocorrelator to measure the actual pulse duration.

  3. Hybrid fs/ps CARS for Sooting and Particle-laden Flames [PowerPoint

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmeister, Kathryn N. Gabet; Guildenbecher, Daniel Robert; Kearney, Sean P.

    2016-01-01

    We report the application of ultrafast rotational coherent anti-Stokes Raman scattering (CARS) for temperature and relative oxygen concentration measurements in the plume emanating from a burning aluminized ammonium perchlorate propellant strand. Combustion of these metal-based propellants is a particularly hostile environment for laserbased diagnostics, with intense background luminosity, scattering and beam obstruction from hot metal particles that can be as large as several hundred microns in diameter. CARS spectra that were previously obtained using nanosecond pulsed lasers in an aluminumparticle- seeded flame are examined and are determined to be severely impacted by nonresonant background, presumably as a result of the plasma formed by particulateenhanced laser-induced breakdown. Introduction of fs/ps laser pulses enables CARS detection at reduced pulse energies, decreasing the likelihood of breakdown, while simultaneously providing time-gated elimination of any nonresonant background interference. Temperature probability densities and temperature/oxygen correlations were constructed from ensembles of several thousand single-laser-shot measurements from the fs/ps rotational CARS measurement volume positioned within 3 mm or less of the burning propellant surface. Preliminary results in canonical flames are presented using a hybrid fs/ps vibrational CARS system to demonstrate our progress towards acquiring vibrational CARS measurements for more accurate temperatures in the very high temperature propellant burns.

  4. Hybrid fs/ps CARS for Sooting and Particle-laden Flames

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmeister, Kathryn N. Gabet; Guildenbecher, Daniel Robert; Kearney, Sean P.

    2015-12-01

    We report the application of ultrafast rotational coherent anti-Stokes Raman scattering (CARS) for temperature and relative oxygen concentration measurements in the plume emanating from a burning aluminized ammonium perchlorate propellant strand. Combustion of these metal-based propellants is a particularly hostile environment for laserbased diagnostics, with intense background luminosity, scattering and beam obstruction from hot metal particles that can be as large as several hundred microns in diameter. CARS spectra that were previously obtained using nanosecond pulsed lasers in an aluminumparticle- seeded flame are examined and are determined to be severely impacted by nonresonant background, presumably as a result of the plasma formed by particulateenhanced laser-induced breakdown. Introduction of fs/ps laser pulses enables CARS detection at reduced pulse energies, decreasing the likelihood of breakdown, while simultaneously providing time-gated elimination of any nonresonant background interference. Temperature probability densities and temperature/oxygen correlations were constructed from ensembles of several thousand single-laser-shot measurements from the fs/ps rotational CARS measurement volume positioned within 3 mm or less of the burning propellant surface. Preliminary results in canonical flames are presented using a hybrid fs/ps vibrational CARS system to demonstrate our progress towards acquiring vibrational CARS measurements for more accurate temperatures in the very high temperature propellant burns.

  5. Role of insulin receptor and insulin signaling on αPS2CβPS integrins' lateral diffusion.

    Science.gov (United States)

    Mainali, Dipak; Syed, Aleem; Arora, Neha; Smith, Emily A

    2014-12-01

    Integrins are ubiquitous transmembrane receptors with adhesion and signaling properties. The influence of insulin receptor and insulin signaling on αPS2CβPS integrins' lateral diffusion was studied using single particle tracking in S2 cells before and after reducing the insulin receptor expression or insulin stimulation. Insulin signaling was monitored by Western blotting for phospho-Akt expression. The expression of the insulin receptor was reduced using RNA interference (RNAi). After insulin receptor RNAi, four significant changes were measured in integrin diffusion properties: (1) there was a 24% increase in the mobile integrin population, (2) 14% of the increase was represented by integrins with Brownian diffusion, (3) for integrins that reside in confined zones of diffusion, there was a 45% increase in the diameter of the confined zone, and (4) there was a 29% increase in the duration integrins spend in confined zones of diffusion. In contrast to reduced expression of the insulin receptor, which alters integrin diffusion properties, insulin stimulation alone or insulin stimulation under conditions of reduced insulin receptor expression have minimal effects on altering the measured integrin diffusion properties. The differences in integrin diffusion measured after insulin receptor RNAi in the presence or absence of insulin stimulation may be the result of other insulin signaling pathways that are activated at reduced insulin receptor conditions. No change in the average integrin diffusion coefficient was measured for any conditions included in this study.

  6. Positron Annihilation in the Bipositronium Ps2

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Frolov, Alexei M.

    2005-07-01

    The electron-positron-pair annihilation in the bipositronium PS2 is considered. In particular, the two-, three-, one- and zero-photon annihilation rates are determined to high accuracy. The corresponding analytical expressions are also presented. Also, a large number of bound state properties have been determined for this system.

  7. The 4 Ps as a Guiding Perspective

    Science.gov (United States)

    Kalsbeek, David H.

    2013-01-01

    A 4 Ps perspective addresses immediate needs: to help institutions gain traction in their retention strategies by framing and reframing the challenges and the possible responses, by challenging some of the traditional mental models about retention that can distract or dilute those strategies, and by offering focus and coherence to institutional…

  8. 10th Anniversary P.S.

    CERN Multimedia

    Adams,J

    1969-01-01

    John Adams parle de la préhistoire du P.S. avec présentation des dias. Le DG B.Gregory prend la parole. Les organisateurs présentent sous la direction du "Prof.Ocktette"(?) un sketch très humoristique (p.e.existence de Quark etc.....)

  9. Back to work for the PS

    CERN Multimedia

    2006-01-01

    On 22 June, the PS's rotating machine started turning again for the first time since its enforced shutdown one month ago (see Bulletin No. 23-24/2006) - and the PS was back in operation the very next day! A team from Siemens worked their socks off, 6 days a week for one month (including public holidays), to repair the electrical power supply in collaboration with the AB/PO Group's Main Power Converters (MPC) Section. The generator's faulty rotor was dismantled and replaced by the renovated spare rotor. The multitude of electrical and mechanical connections together with the sheer weight of the rotor (80 tonnes) made this an extremely complex job. The AB/PO Group used the shutdown to test a back-up solution for the PS power supply. The accelerator was directly wired up to the 18 kV electrical network via a 13 MVA transformer, installed at the end of the 1970s but never used. This solution succeeded in bringing the PS back into operation but at limited energy and frequency. Just 14 GeV could be achieved, whic...

  10. Diagnostics of pulse contrast for petawatt laser in SGII

    Science.gov (United States)

    Ouyang, Xiaoping; Liu, Daizhong; Zhu, Baoqiang; Zhu, Jian; Zhu, Jianqiang

    2015-02-01

    Pulse contrast is an important parameter for ultrafast pulses. It shall be 108 or higher in order to avoid effect from noise before main pulse. Diagnostics with cross-correlation can achieve high temporal resolution such as ~7fs. Cross-correlation has advantage in pulse contrast measurement than autocorrelation because it can distinguish noise before or after main pulse. High dynamic range is also essential in pulse contrast measurement. Cross-correlation signal from a single shot is converted into a signal series through fiber array, which can be analyzed by a set of a PMT and an oscilloscope. Noise from nonlinear crystal and scatter needs decrease to improve dynamic range. And pulse power is also discussed in pulse contrast experiments. Time delay τ is generated by travel stage in measurement for repetition pulses. Then energy instability will generate error in this measurement. In measurement for single shot pulse, time delay τ is generated by slant angle of beams. The scanning procession is completed with thousands parts of beam section within a single shot, and error will generated from no uniformity in near field. Performance test of pulse contrast measurement is introduced in subsequent sections. Temporal resolution is testified by self-calibration. Dynamic range is judged by a parallel flat. At last pulse contrast of petawatt laser is diagnosed by a single shot cross-correlator with high confidence. The ratio is 10-6 at 50ps before main pulse, and 10-4 at 10ps before main pulse.

  11. Demonstration of an ultraviolet stimulated Brillouin scattering pulse compressed hundred picosecond laser in LiB3O5 crystals

    Science.gov (United States)

    Bai, Zhenxu; Wang, Yulei; Lu, Zhiwei; Jiang, Li; Yuan, Hang; Liu, Zhaohong

    2017-08-01

    A hundred picosecond ultraviolet (UV) laser is demonstrated with a pulse duration of less than 200 ps and peak power of 0.6 GW. With a hundred picosecond stimulated Brillouin scattering compressed pulse as the fundamental light, the UV output at 355 nm is obtained by extra-cavity sum-frequency-mixing in two LiB3O5 crystals. Maximum UV energy was 100 mJ when the incident energy was 280 mJ, yielding an optical-to-optical efficiency of 35.7%. This result is of interest for the generation of high energy sub-nanosecond UV lasers which finds applications in shock ignition and industrial processing.

  12. Formation of upconversion nanoparticles of 18%Yb:1%Er:NAYF4 by ultra-short pulse laser ablation in water

    Science.gov (United States)

    Gemini, Laura; Hernandez, Marie-Caroline; Kling, Rainer

    2016-03-01

    Pulsed laser ablation in liquid (PLAL) is nowadays gaining popularity as innovative, reliable and efficient technique to produce high-purity nanoparticles (NPs) of many inorganic and organic materials. In this context, attention has been recently focused on luminescent up-conversion NPs (UCNPs) which, being characterized by sharp emission bands in ultraviolet (UV)-to-near-infrared (NIR) range upon NIR irradiation, are in fact of great interest in many biological and biomedical applications. Moreover, with respect to organic dyes NPs and quantum dots, UCNPs show less toxicity, increased chemical stability, long-lifetime decays and lack of photo-bleaching. Our research focuses on generation of UCNPs of rare earth lanthanide-doped crystalline material, namely 18%Yb:1%Er:NAYF4, by PLAL in water. It is well known that optical properties of NPs strongly depend on their features, as for instance size and shape, which in turn may be controlled by laser ablation parameters. Therefore, two different laser sources are used for the ablation processes in order to find the set of laser parameter, i.e. pulse duration, laser fluence and repetition rate, for which the luminescence of UPNPs is optimized: (i) Amplitude Satsuma HP3 system: 330 fs pulse duration, 1030 wavelength and (ii) Eolite Hegoa system: 50 ps pulse duration, 1030 nm wavelength. UCNPs are finally characterized by spectrophotometer analyses to define emission range and intensity under NIR light and by transmission electron microscopy (TEM) to determine their size and shape.

  13. Long-pulse Supercontinuum Light Sources

    DEFF Research Database (Denmark)

    Moselund, Peter M.

    A Supercontinuum (SC) is a broad spectrum generated from a narrow light source through non-linear effects. This thesis describes SC generation based on 1064 nm ps pulses in PCF fibres. We investigate how the SC spectrum can be modified and intensity noise reduced by feeding back part of the SC...

  14. Tunable CO2 laser system with subnanosecond-pulse-train output

    Science.gov (United States)

    Kimura, W. D.

    2017-02-01

    A CO2 laser system has been demonstrated that generates a train of subnanosecond pulses tunable over the P and R branches of the CO2 laser spectrum at 9-11 μm. It utilizes optical free induction decay to generate a single 100-ps laser pulse from a tunable transverse-excited-atmospheric CO2 laser. This laser pulse is injection-seeded into a high-pressure CO2 oscillator whose output consists of a train of amplified 100-ps pulses with maximum pulse energy of 30 mJ, corresponding to a peak power of 300 MW. The 100-ps, tunable, infrared laser pulses are needed for a new technique to remotely detect atmospheric gaseous molecules, which relies on the train of CO2 laser pulses selectively exciting the target molecules whose presence is then revealed using a separate terahertz probe beam.

  15. Analysis of ceramics surface modification induced by pulsed laser treatment

    Directory of Open Access Journals (Sweden)

    Slavica Ristić

    2014-03-01

    Full Text Available This paper presents the effects of laser light irradiation on the surface of ceramics dating from archaeological site Stubline (Obrenovac, Belgrade, Serbia. Two different pulsed lasers: TEA CO2 (10.6 µm wavelength, pulse duration tp = 100 ns and Nd:YAG (wavelengths 1064 nm and 532 nm, tp = 150 ps have been used for surfaces treatment. Laser irradiation fluence was in the range of 1–20 J/cm2. Ceramics surface modifications induced by pulsed laser treatment were examined by scanning electron microscope, SEM, and the composition with energy dispersive X-ray, EDX, analysis. The tests were performed in order to obtain as much as possible information about the appropriate choice of materials and techniques for the further conservation and restoration of these items. The second objective was to determine the surface modifications induced by pulsed laser treatment above damage threshold (a safe cleaning laser fluence, as an important parameter in the use of lasers for the cleaning of cultural ceramic items.

  16. Synchronization of picosecond laser pulses to the target X-ray pulses at SPring-8

    CERN Document Server

    Tanaka, Y; Kitamura, H; Ishikawa, T

    2001-01-01

    Synchronization system between an intense picosecond laser and the target X-ray pulses has been developed at SPring-8. The intense laser pulses were obtained by amplification of the pulses picked up from a mode-locked Ti:sapphire laser synchronized with the radio frequency of the storage ring. The repetition rate of amplified laser pulses was controlled to be 1/n of the RF, where n is a multiple of the number of RF buckets in the ring, so that the laser pulses meet the SR pulses originated from a particular electron bunch in partial filling patterns. The temporal overlap of the laser and the target X-ray pulses was achieved as monitored with a streak camera in synchroscan and repetitive single shot operation modes, and was stable with a precision of a few ps for several hours.

  17. PS overcomes two serious magnet failures

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Two magnets (no.'s 6 and 19)and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators' spring start-up to two weeks. Pictured here are members of the PS team with the replacement no. 6 magnet. From left to right: In the back row, Frédéric Roussel (Transport DBS), Yves Bernard (Transport DBS), Luc Moreno (Cegelec), Thierry Battimanza (Transport DBS), Raymond Brown (AB/ABP), Thomas Zickler (AT/MEL); at the front, Steven Southern (AT/VAC), Thierry Gaidon (Brun & Sorensen), Philippe Vidales (Cegelec), Daniel Aubert (Cegelec), Jerome Cachet (Transport DBS), Jose Manual Gomes de Faria (AT/MEL), Eric Page (AT/VAC).

  18. PS overcomes two serious magnet failures

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Two magnets and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators´ spring start-up to two weeks. Here we see one of the replacement magnets (no. 19) being prepared.

  19. The PS overcomes two serious magnet failures

    CERN Multimedia

    2003-01-01

    Two magnets and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators' spring start-up to two weeks.

  20. Motor-Generator Set, PS Main Supply

    CERN Multimedia

    CERN PhotoLab

    1983-01-01

    This is the "new" motor-generator set. It replaced the previous, original, one which had served from the PS start-up in 1959. Ordered in 1965, installed in 1967, it was brought into operation at the beginning of 1968. Regularly serviced and fitted with modern regulation and controls, it still serves at the time of writing (2006) and promises to serve for several more years, as a very much alive museum-piece. See also 6803016 and 0201010.

  1. Measuring target for the PS Booster

    CERN Multimedia

    1971-01-01

    The measuring target for the PS Booster (originally 800 MeV, now 1.4 GeV). It measures the size of the beam by destroying all particles with amplitudes greater than the size of the fork, the position and width of which are adjustable. The plunging time is only 20 ms and the acceleration at the tip of the fork reaches 90 g. The servo-controlled linear motor is shown detached from the mechanism. See also 7602008.

  2. Memories of the PS and of LEP

    CERN Document Server

    Steinberger, Jack

    2012-01-01

    The CERN PS, which started in 1959, and the Brookhaven AGS in 1960, represented an advance by a factor of more than five in the energy of proton accelerators, from the 5 GeV of the Berkeley Bevatron to about 30 GeV. These accelerators made possible the large progress in our understanding of particles and their interactions over the next two decades, culminating in the electroweak and QCD gauge theories.

  3. PS overcomes two serious magnet failures

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Two magnets and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators' spring start-up to two weeks. Here we see one of the replacement magnets (no. 6) being prepared.

  4. High energy noise-like pulsing in a double-clad Er/Yb figure-of-eight fiber laser.

    Science.gov (United States)

    Lauterio-Cruz, J P; Hernandez-Garcia, J C; Pottiez, O; Estudillo-Ayala, J M; Kuzin, E A; Rojas-Laguna, R; Santiago-Hernandez, H; Jauregui-Vazquez, D

    2016-06-27

    In this work, we study a 215-m-long figure-of-eight fiber laser including a double-clad erbium-ytterbium fiber and a nonlinear optical loop mirror based on nonlinear polarization evolution. For proper adjustments, self-starting passive mode-locking is obtained. Measurements show that the mode-locked pulses actually are noise-like pulses, by analyzing the autocorrelation, scope traces and the very broad and flat spectrum extending over a record bandwidth of more than 200 nm, beyond the 1750 nm upper wavelength limit of the optical spectrum analyzer. Noise-like pulsing was observed for moderate and high pump power preserving the same behavior, reaching pulse energies as high as 300 nJ, with pulse durations of a few tens of ns and a coherence length in the order of 1 ps. Stable fundamental mode locking as well as harmonic mode locking up to the 6th order were observed. The bandwidth was further extended to more than 450 nm when a 100-m piece of highly nonlinear fiber was inserted at the laser output. The enhanced performances obtained compared to other similar schemes could be related to the absence of a polarizer in the present setup, so that the state of polarization along the cavity is no longer restricted.

  5. Enhanced personal protection system for the PS

    CERN Multimedia

    Caroline Duc

    2013-01-01

    During the first long shutdown (LS1) a new safety system will be installed in the primary beam areas of the PS complex in order to bring the standard of personnel radiation protection at the PS into line with that of the LHC.   Pierre Ninin, deputy group leader of GS-ASE and responsible for the installation of the new PS complex safety system, in front of a new access control system. The LHC access control systems are state-of-the-art, whereas those of the injection chain accelerators were running the risk of becoming obsolete. For the past two years a project to upgrade the access and safety systems of the first links in the LHC accelerator chain has been underway to bring them into compliance with nuclear safety standards. These systems provide the personnel with automatic protection by limiting access to hazardous areas and by ensuring that nobody is present in the areas when the accelerator is in operation. By the end of 2013, the project teams will ha...

  6. Fast heating of fuel assembled in a spherical deuterated polystyrene shell target by counter-irradiating tailored laser pulses delivered by a HAMA 1 Hz ICF driver

    Science.gov (United States)

    Mori, Y.; Nishimura, Y.; Hanayama, R.; Nakayama, S.; Ishii, K.; Kitagawa, Y.; Sekine, T.; Takeuchi, Y.; Kurita, T.; Satoh, N.; Kawashima, T.; Komeda, O.; Nishi, T.; Azuma, H.; Hioki, T.; Motohiro, T.; Sunahara, A.; Sentoku, Y.; Miura, E.

    2017-11-01

    Fast heating is a method of heating an assembled high-density plasma into a hot state by irradiating it with short-duration (sub-picosecond), high-intensity (> 1018 W cm-2 ) laser pulses before the plasma expands and dissolves hydrodynamically. In this paper, we present detailed experimental results of fast heating fuel assembled in a spherical deuterated polystyrene shell target of 500 μ m diameter and 7 μm thickness with counterbeam illumination by using a HAMA 1 Hz, 5.9 J inertial confinement fusion laser driver with pulse tailoring. These tailored pulses contain three pulses in sequence: a ‘foot’ pulse of 2.4 J/25 ns, a ‘spike’ pulse of 0.5 J/300 ps and a ‘heater’ pulse of 0.4 J/110 fs; these pulses are designed to assemble the fuel and heat it. By varying the energy of the foot pulse, we find that fast heating the fuel is achieved only if the fuel is weakly ablated by the foot pulse and then shock-assembled by the spike pulse into the target centre so that the heater pulse can access the fuel with a focal intensity greater than 1018 W cm-2 . Without a foot pulse, the heater pulse contributes to assembling the fuel. For higher foot-pulse energies, the heater pulse drives a hydrodynamic motion with speeds of the order 107 cm s-1 with intensities of the order 1017 W cm-2 , resulting in re-assembling and additional heating of the pre-assembled fuel. Once a shock-assembled core is achieved at the target centre, we succeed qualitatively in fast heating the core for shots in sequence with variations of laser energy within 18%. The coupling efficiency from the heating laser to the core is inferred to be (10 +/- 2) % in total: (8 +/- 1.6) % for the ionized bulk electrons and (2 +/- 0.4) % for the bulk ions. The fusion neutron spectrum detected on the laser axis exhibits peaks at 1.0 MeV, 1.7 MeV and 3.8 MeV. These peaks are attributed to the C(d, n){\\hspace{0pt}}13 N and d(d, n){\\hspace{0pt}}3 He reactions induced by counterpropagating fast deuterons

  7. Flat-top pulse generation by the optical Fourier transform technique for ultrahigh speed signal processing

    DEFF Research Database (Denmark)

    Palushani, Evarist; Oxenløwe, Leif Katsuo; Galili, Michael

    2009-01-01

    This paper reports on the generation of 1.6-ps fullwidth at half-maximum flat-top pulses by the optical Fourier transform technique, and the utilization of these pulses in a 320-Gb/s demultiplexing experiment. It is demonstrated how a narrow pulse having a 15-nm wide third-order super...

  8. Ablation of steel by microsecond pulse trains

    Science.gov (United States)

    Windeler, Matthew Karl Ross

    Laser micromachining is an important material processing technique used in industry and medicine to produce parts with high precision. Control of the material removal process is imperative to obtain the desired part with minimal thermal damage to the surrounding material. Longer pulsed lasers, with pulse durations of milli- and microseconds, are used primarily for laser through-cutting and welding. In this work, a two-pulse sequence using microsecond pulse durations is demonstrated to achieve consistent material removal during percussion drilling when the delay between the pulses is properly defined. The light-matter interaction moves from a regime of surface morphology changes to melt and vapour ejection. Inline coherent imaging (ICI), a broadband, spatially-coherent imaging technique, is used to monitor the ablation process. The pulse parameter space is explored and the key regimes are determined. Material removal is observed when the pulse delay is on the order of the pulse duration. ICI is also used to directly observe the ablation process. Melt dynamics are characterized by monitoring surface changes during and after laser processing at several positions in and around the interaction region. Ablation is enhanced when the melt has time to flow back into the hole before the interaction with the second pulse begins. A phenomenological model is developed to understand the relationship between material removal and pulse delay. Based on melt refilling the interaction region, described by logistic growth, and heat loss, described by exponential decay, the model is fit to several datasets. The fit parameters reflect the pulse energies and durations used in the ablation experiments. For pulse durations of 50 us with pulse energies of 7.32 mJ +/- 0.09 mJ, the logisitic growth component of the model reaches half maximum after 8.3 mus +/- 1.1 us and the exponential decays with a rate of 64 mus +/- 15 us. The phenomenological model offers an interpretation of the material

  9. Coiled transmission line pulse generators

    Science.gov (United States)

    McDonald, Kenneth Fox

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  10. Effects of an additional pressure support level on exercise duration in patients on prolonged mechanical ventilation.

    Science.gov (United States)

    Chen, Yen-Huey; Lin, Hui-Ling; Hsiao, Hsiu-Feng; Huang, Ching-Tzu; Kao, Kuo-Chin; Li, Li-Fu; Huang, Chung-Chi; Tsai, Ying-Huang

    2015-12-01

    Noninvasive positive pressure ventilation has been regarded as a strategy for improving exercise performance. Whether an increase in the ventilatory support level improves exercise performance in patients who have received invasive ventilation is unknown. The purpose of this study is to examine the effects of an additional level of pressure support (PS) ventilation on exercise tolerance in patients undergoing prolonged mechanical ventilation (PMV). This study examined 15 patients who were undergoing PMV. All patients performed an upper-arm exercise test at three PS levels: the baseline PS level (PS), a level 2 cmH2O higher than the baseline level (PS+2), and a level 4 cmH2O higher than the baseline level (PS+4). The physiological response, reasons for discontinuing the exercise test, and exercise duration were recorded and analyzed. The tidal volume increased significantly from 271.7 ± 54.7 mL to 398.3 ± 88.7 mL at the PS+4 level (p = 0.01). Significant differences in exercise duration were observed at different PS levels. The exercise duration was significantly longer at the PS+4 level than at the PS and PS+2 levels (146.3 ± 139.9 seconds vs. 108.5 ± 85.9 seconds vs. 72.8 ± 43.9 seconds, p = 0.038) as their corresponding order. There were significant relationships between resting respiratory rate and exercise duration at the PS (r = -0.639, p = 0.034) and PS+2 levels (r = -0.668, p = 0.025). In patients undergoing PMV, an additional PS level of up to 4 cmH2O compared with the baseline setting may help to improve exercise tolerance by prolonging exercise duration. Copyright © 2014. Published by Elsevier B.V.

  11. Photoionization of a Statistic Atom by Ultrashort Wavelet Pulses

    Science.gov (United States)

    Astapenko, V. A.; Ionichev, E. Yu.; Yakovets, A. V.

    2017-10-01

    Photoionization of atoms by ultrashort electromagnetic wavelet pulses is investigated within the framework of a statistical model. Integral representations of the total probability of atom ionization are obtained within the time over which the pulse acts. It is shown that the dependence of this probability on the pulse duration in the considered case is bell-shaped. The wavelet pulse duration at which the maximum photoionization probability is reached is determined for different charges of atomic nuclii.

  12. Efficient energetic proton generation driven by ultrashort ultraintense ti:Sapphire laser pulse

    Energy Technology Data Exchange (ETDEWEB)

    Choi, I. W.; Kim, C. M.; Jeong, T. M.; Yu, T. J.; Sung, J. H.; Lee, S. K.; Hafz, N.; Pae, K. H.; Ko, D. K.; Lee, J. [Gwangju Institute of Science and Technology, Gwangju (Korea, Republic of); Nishiuchi, M.; Daido, H.; Yogo, A.; Orimo, S.; Ogura, K.; Ma, J.; Sagisaka, A.; Mori, M.; Pirozhkov, A. S.; Kiriyama, H.; Bulanov, S. V.; Esirkepov, T. Zh. [Japan Atomic Energy Agency, Kyoto (Japan); Oishi, Y.; Nemoto, K. [Central Research Institute of Electronic Power Industry, Kanagawa (Japan)

    2008-11-15

    Significant progress on laser driven proton generation has been made in the past few years. Proton acceleration driven by ultrashort ultraintense laser pulse has been a promising technology for realizing a compact accelerator. Laser driven protons have several unique properties, such as shot pulse duration of ∼ps, high peak current in kA range, low transverse emittance below 10{sup -}2{sup m}m mrad, and good laminarity. For practical applications, the proton beam should be optimized to obtain higher energy, narrower energy spread, larger number and conversion efficiency. Maximum proton energy of 58 MeV has been demonstrated using PW class laser pulse, and quasi monoenergetic protons were produced from microstructured target. We have performed series of experiments to generate energetic proton beam by collaborating with JAEA and CRIEPI groups. Energetic protons were produced by the interaction of ultrashort ultraintense laser pulse with thin solid targets. Laser pulse with maximum energy of 1.7 J and minimum pulse duration of 34 FS, giving maximum peak intensity 3x10{sup 1}9{sup W}/cm{sup 2,} was focused using an off axis parabolic mirror at 45 degree incident angle with p polarization. The target used was one of 5μm thick copper of 7.5, 12.5, 25μm thick polyimide foils. Fresh Surface of target was supplied by moving the target with tape target driver for every laser shot, performing repetitive laser shooting without breaking vacuum. In order to investigate optimal generation conditions, we varied the laser pulse width and changed target position with respect to a tight focus position of laser beam. Main proton diagnostic was proton time of flight spectrometer to facilitate real time optimization of the laser and target conditions. Energetic protons with maximum energy of up to 4 MeV are generated by the interaction of laser pulse with a 7.5μm thick Polyimide target. The conversion efficiency from the laser energy into the proton kinetic energies is achieved to

  13. Psühhodramaatikud annavad Pärnus eksami

    Index Scriptorium Estoniae

    2008-01-01

    29. maist kuni 1. juunini kestab Pärnus psühhodraama konverents "Geeniuste kohtumine", kus rahvusvahelise koolituse läbinud annavad eksami. Ruuda Palmquist on psühhodraama kui teadusharu rajajaid Eestis. Pärnus on kohal Rootsi Moreno Instituudi juhataja, psühhodraama lavastaja Marc Treadwell

  14. Experimental investigation of high energy noise-like pulses from a long cavity erbium-doped fiber laser

    Science.gov (United States)

    Li, Kexuan; Guoyu, Heyang; Tian, Jinrong; Song, Yanrong

    2016-11-01

    The high energy noise-like pulses (NLPs) were experimentally investigated in a passively mode-locked erbium-doped fiber laser with a long ring cavity by using nonlinear polarization rotation technique. Large net normal group-velocity dispersion of the cavity is estimated as high as 6.46 ps2, which is beneficial to formation of high-energy pulses. With the total pump power of 970 mW (the pump powers of forward pump and backward pump are set at the value of 455 mW and 515 mW, respectively), a stable ultrahigh energy rectangular-shape pulse emission with the pulse duration of 35 ns was observed. The energy of square packet with a fundamental repetition rate of 141.6 kHz is as high as 840 nJ. The signal-to-noise is higher than 60 dB in RF spectrum. The feature of NLPs is confirmed by the coherent spike of autocorrelation trace. When the pump power is beyond 970 mW, the mode locking operation with fundamental repetition rate cannot be achieved despite of the large range variation of polarization controller (PC) settings. However, the forthorder harmonic mode locking can be observed, the square pulse packet duration still remains at ˜ 35 ns. The experimental results demonstrated that the ultrahigh energy NLPs is only realized at the condition of special physical parameters and it is restricted by the number and intensity of ultra short pulses within the envelope to some extent.

  15. Root-flipped multiband refocusing pulses.

    Science.gov (United States)

    Sharma, Anuj; Lustig, Michael; Grissom, William A

    2016-01-01

    To design low peak power multiband refocusing radiofrequency pulses, with application to simultaneous multislice spin echo MRI. Multiband Shinnar-Le Roux β polynomials were designed using convex optimization. A Monte Carlo algorithm was used to determine patterns of β polynomial root flips that minimized the peak power of the resulting refocusing pulses. Phase-matched multiband excitation pulses were also designed to obtain linear-phase spin echoes. Simulations compared the performance of the root-flipped pulses with time-shifted and phase-optimized pulses. Phantom and in vivo experiments at 7T validated the function of the root-flipped pulses and compared them to time-shifted spin echo signal profiles. Averaged across number of slices, time-bandwidth product, and slice separation, the root-flipped pulses have 46% shorter durations than time-shifted pulses with the same peak radiofrequency amplitude. Unlike time-shifted and phase-optimized pulses, the root-flipped pulses' excitation errors do not increase with decreasing band separation. Experiments showed that the root-flipped pulses excited the desired slices at the target locations, and that for equivalent slice characteristics, the shorter root-flipped pulses allowed shorter echo times, resulting in higher signal than time-shifted pulses. The proposed root-flipped multiband radiofrequency pulse design method produces low peak power pulses for simultaneous multislice spin echo MRI. © 2015 Wiley Periodicals, Inc.

  16. Efficient chirped-pulse amplification of sub-20 fs laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Matsuoka, Shinichi; Yamakawa, Koichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-03-01

    We have developed a model for ultrabroadband and ultrashort pulse amplification including the effects of a pulse shaper for regenerative pulse shaping, gain narrowing and gain saturation in the amplifiers. Thin solid etalons are used to control both gain narrowing and gain saturation during amplification. This model has been used to design an optimized Ti:sapphire amplifier system for producing efficiently pulses of < 20-fs duration with approaching peak and average powers of 100 TW and 20 W. (author)

  17. Psychometric properties of the French translation of the reduced KOOS and HOOS (KOOS-PS and HOOS-PS)

    DEFF Research Database (Denmark)

    Ornetti, P; Perruccio, A V; Roos, E M

    2009-01-01

    OBJECTIVE: To evaluate the psychometric properties of the French KOOS physical function (KOOS-PS) and HOOS physical function (HOOS-PS), specifically its feasibility, reliability, construct validity, and responsiveness. METHODS: Consecutive outpatients consulting for primary knee or hip osteoarthr......OBJECTIVE: To evaluate the psychometric properties of the French KOOS physical function (KOOS-PS) and HOOS physical function (HOOS-PS), specifically its feasibility, reliability, construct validity, and responsiveness. METHODS: Consecutive outpatients consulting for primary knee or hip...

  18. Evolving science enhanced with iPS

    Directory of Open Access Journals (Sweden)

    Editor

    2007-11-01

    Full Text Available Dear friends, Greetings from all in the team. With the stage set for online submissions and the review-response-revision-resubmission process standardized, we have come with the first regular issue and from now there will be quarterly issues of the journal. Since the starting of the JSRM in a short span there have been a lot of developments, which we would rather say as "evolutions" keeping in mind, the recent iPS! This evolution we would like you to see from a background of the various developments in the art and science of medicine throughout in the past three centuries. We have come across the era of investigative tools such as bamboo made laryngoscopes to era of vaccines and antibiotics followed by the era of revolutionary non-invasive procedures and recently the nano technology based drugs and now the iPS! Macro to Micro, but still more to go. All through the influence of the society, religions, philosophies have been playing a very important role in every step the science of biology moves ahead. Starting with the contraception, assisted reproduction then the gene modified plants....and now the embryonic stem cells! With the advent of the iPS, though the issues of oncogenes, teratoma yet to be ruled out, we have found there is a way which can bypass the ES cells! Hats off to those scientists who have burnt their midnight oil to have found this way out! The lesson we learn is to explore things with an open mind and continue to proceed further without spending much time fingers crossed. Yours sincerely,The Editorial team.

  19. Spectral investigation of highly ionized bismuth plasmas produced by subnanosecond Nd:YAG laser pulses

    Science.gov (United States)

    Wu, Tao; Higashiguchi, Takeshi; Li, Bowen; Arai, Goki; Hara, Hiroyuki; Kondo, Yoshiki; Miyazaki, Takanori; Dinh, Thanh-Hung; Dunne, Padraig; O'Reilly, Fergal; Sokell, Emma; O'Sullivan, Gerry

    2016-02-01

    The unresolved transition arrays (UTAs) emitted from laser produced bismuth (Bi) plasma sources show potential for single-shot live cell imaging. We have measured extreme ultraviolet spectra from bismuth laser produced plasmas in the 1-7 nm region using a λ = 1064 nm Nd:YAG laser with a pulse duration of 150 ps. Comparison of spectra obtained under different laser power densities with calculations using the Hartree-Fock with configuration interaction Cowan suite of codes and the UTA formalism, as well as consideration of previous predictions of isoelectronic trends, are employed to identify lines and a number of new features in spectra from Bi XXIII to Bi XLVII. The results show that Δn = 0, n = 4-4 emission from highly charged ions merges to form intense UTAs in the 4 nm region and Δn = 1, n = 4-5 resonance transitions UTAs dominate the 1-3 nm region of the Bi spectrum.

  20. Mid-infrared mode-locked pulse generation with multilayer black phosphorus as saturable absorber.

    Science.gov (United States)

    Qin, Zhipeng; Xie, Guoqiang; Zhao, Chujun; Wen, Shuangchun; Yuan, Peng; Qian, Liejia

    2016-01-01

    A mid-infrared saturable absorber mirror is successfully fabricated by transferring the mechanically exfoliated black phosphorus onto the gold-coated mirror. With the as-prepared black phosphorus saturable absorber mirror, a continuous-wave passively mode-locked Er:ZBLAN fiber laser is demonstrated at the wavelength of 2.8 μm, which delivers a maximum average output power of 613 mW, a repetition rate of 24 MHz, and a pulse duration of 42 ps. To the best of our knowledge, this is the first time a black phosphorus mode-locked laser at 2.8 μm wavelength has been demonstrated. Our results demonstrate the feasibility of black phosphorus flake as a new two-dimensional material for application in mid-infrared ultrafast photonics.

  1. Position pickup of the PS Booster

    CERN Multimedia

    CERN PhotoLab

    1975-01-01

    The beam position around the 4 rings of the PS Booster (originally 800 MeV, now 1.4 GeV), is measured with electrostatic pickups (PU). They consist of a ceramic cylinder forming part of the vacuum chamber, and, in order to save space, they are located inside the multipole lenses. The inside of the ceramic is coated with a metallic layer, into which the form of the electrodes was cut by computer-controlled micro-sandblasting. Each PU has a pair of horizontal and a pair of vertical electrodes, as well as a separate intensity-sensing circular electrode.

  2. Space charge studies in the PS

    CERN Document Server

    Asvesta, F; Damerau, H; Huschauer, A; Papaphilippou, Y; Serluca, M; Sterbini, G; Zisopoulos, P

    2017-01-01

    In this paper the results of Machine Development (MD)studies conducted at the CERN Proton Sychrotron (PS) arepresented. The main focus was the investigation of newworking points in an effort to characterize and potentiallyimprove the brightness for LHC-type beams in view of theLHC Injectors Upgrade (LIU). Various working points werecompared in terms of losses and emittance evolution. Sincespace charge and the resonances it excites are the main causefor emittance blow-up and losses, tunes close to excitedresonances were carefully studied. Mitigation techniques,such as bunch flattening using a double harmonic RF system,were also tested.

  3. Pulse-to-pulse intensity modulation and drifting subpulses in recycled pulsars

    OpenAIRE

    Edwards, R; Stappers, B. W.

    2003-01-01

    We report the detection of pulse-to-pulse periodic intensity modulations, in observations of recycled pulsars. Even though the detection of individual pulses was generally not possible due to their low flux density and short duration, through the accumulation of statistics over sequences of 10^5--10^6 pulses we were able to determine the presence and properties of the pulse-to-pulse intensity variations of six pulsars. In most cases we found that the modulation included a weak, broadly quasi-...

  4. High-intensity, high-contrast laser pulses generated from the fully diode-pumped Yb:glass laser system POLARIS.

    Science.gov (United States)

    Hornung, Marco; Keppler, Sebastian; Bödefeld, Ragnar; Kessler, Alexander; Liebetrau, Hartmut; Körner, Jörg; Hellwing, Marco; Schorcht, Frank; Jäckel, Oliver; Sävert, Alexander; Polz, Jens; Arunachalam, Ajay Kawshik; Hein, Joachim; Kaluza, Malte C

    2013-03-01

    We report on the first generation of high-contrast, 164 fs duration pulses from the laser system POLARIS reaching focused peak intensities in excess of 2×10(20) W/cm2. To our knowledge, this is the highest peak intensity reported so far that has been achieved with a diode-pumped, solid-state laser. Several passive contrast enhancement techniques have been specially developed and implemented, achieving a relative prepulse intensity smaller than 10(-8) at t=-30 ps before the main pulse. Furthermore a closed-loop adaptive-optics system has been installed. Together with angular chirp compensation, this method has led to a significant reduction of the focal spot size and an increase of the peak intensity.

  5. PAN/PS elctrospun fibers for oil spill cleanup

    Science.gov (United States)

    Ying, Qiao; Lili, Zhao; Haixiang, Sun; Peng, Li

    2014-08-01

    A high-capacity oil sorbent was fabricated by electrospinning using PS/PAN blend. Morphology, contact angle and oil adsorption of PAN/PS fiber and PP nonwoven fabric were studied. It was found that the PAN/PS fiber had a smaller diameter than PP, and the maximum sorption capacities of the PAN/PS sorbent for pump oil, peanut oil, diesel, and gasoline were 194.85, 131.7, 66.75, and 43.38 g/g, which were far higher than those of PP. The sorbent PS/PAN fiber showed a contact angle of water144.32° and diesel oil 0°. The sorption kinetics of PAN/PS and PP sorbent were also investigated. Compared with the commercial PP fabric, the PAN/PS fiber seems to have the ability to be used in oil-spill cleanup application.

  6. Chemotherapy and quality of life in NSCLC PS 2 patients

    DEFF Research Database (Denmark)

    Helbekkmo, Nina; Strøm, Hans H; Sundstrøm, Stein H

    2009-01-01

    INTRODUCTION: Nearly 40% of patients with advanced NSCLC are in performance status (PS) 2. These patients have a shorter life expectancy than PS 0/1 patients and they are underrepresented in clinical trials. Data on how platinum-based combination chemotherapy affects Health Related Quality of Life...... (HRQOL) of patients with PS 2 are scarce and the treatment of this important group of patients is controversial. METHODS: A national multicenter phase III study on platinum based chemotherapy to 432 advanced NSCLC patients included 123 patients with PS 2. To explore the treatment impact on HRQOL......: Whereas the demographic data at baseline were well balanced between the groups, the PS 2 patients had significantly worse function and more severe symptoms than the PS 0/1 patients. In response to combination chemotherapy, the PS 2 patients had a more profound improvement of global QOL, cognitive function...

  7. Effects of duration and timing of prenatal stress on hippocampal myelination and synaptophysin expression.

    Science.gov (United States)

    Xu, Jian; Yang, Bo; Yan, Chonghuai; Hu, Howard; Cai, Shizhong; Liu, Junxia; Wu, Meiqin; Ouyang, Fengxiu; Shen, Xiaoming

    2013-08-21

    The relationship between prenatal stress (PS) exposure and neurodevelopmental deficits remains inconclusive, especially when assessing the role of PS duration and timing and sex-dependent effects. This study explored a sex-specific association between the duration and timing of exposure and the outcomes of PS-induced neurotoxicity in hippocampal microstructure, synaptophysin expression, and neurobehavioral performance in rats. Pregnant rats were randomly assigned to control, PS-ML (exposed to prenatal restraint stress in the mid-to-late period of pregnancy), or PS-L (exposed in the late period of pregnancy) groups, and offspring in each group were divided into two subgroups by sex. Surface-righting reflex test, cliff avoidance test and Morris water maze test showed that neurodevelopmental levels were reduced in PS-treated pups but without significant sex differences. On postnatal day 22, hippocampal microstructure was examined by electron microscopy, and the expression of hippocampal synaptophysin was assessed by western blot. Abnormal ultrastructural appearance of hippocampal neurons and myelin sheaths, more degenerating neurons and higher G-ratios were found in young PS-ML and PS-L rats as well as reduced expression of hippocampal synaptophysin, although PS-ML pups were more greatly affected than PS-L, with males showing slightly greater impairments than females. These findings suggest that hippocampal hypo-myelination and decreased synaptophysin expression in neurodevelopment may be a duration and time-dependent effect of prenatal stress exposure, modified slightly by sex. Copyright © 2013 Elsevier B.V. All rights reserved.

  8. The PS Booster Fast Wire Scanner

    CERN Document Server

    Burger, S; Priestnall, K; Raich, U

    2003-01-01

    The very tight emittance budget for LHC type beams makes precise emittance measurements in the injector complex a necessity. The PS machine uses 2 fast wire scanners per transverse plane for emittance measurement of the circulating beams. In order to ease comparison the same type of wire scanners have been newly installed in the upstream machine, the PS Booster, where each of the 4 rings is equipped with 2 wire scanners measuring the horizontal and vertical profiles. Those wire scanners use new and more modern control and readout electronics featuring dedicated intelligent motor movement controllers, which relieves the very stringent real time constraints due to the very high speed of 20m/s. In order to be able to measure primary beams at the very low injection energy of the Booster (50MeV) secondary emission currents from the wire can be measured as well as secondary particle flows at higher primary particle energies during and after acceleration. The solution adopted for the control of the devices is descri...

  9. Sofrimento psíquico e trabalho

    Directory of Open Access Journals (Sweden)

    Sarah Rosa Salles Vieira

    2014-03-01

    Full Text Available O presente artigo aprofunda questões clínico-téoricas relacionadas especificamente ao trabalho docente e ao sofrimento psíquico a ele relacionado a partir da observação clínica e vivência grupal nos atendimentos terapêuticos ocupacionais realizados no Hospital do Servidor Público Estadual de São Paulo "Francisco Morato de Oliveira" (HSPE-FMO. Partindo dos estudos acerca da Psicopatologia do Trabalho de Christophe Dejours, do trabalho docente e do relato de um caso clínico, caracteriza a problemática do sofrimento no trabalho, os sistemas de defesa contra este sofrimento, a ameaça à subjetividade do próprio trabalhador, as representações e conflitos vivenciados no trabalho docente, bem como a relação aditiva estabelecida como uma estratégia inconsciente de sobrevivência psíquica.

  10. The PS Booster's ejection kicker: full house.

    CERN Multimedia

    CERN PhotoLab

    1971-01-01

    The modules of the Booster's four-storied full-aperture kicker pretty much fill their vacuum tank (front cover removed). In the original 800 MeV version, the delay-type modules were pulsed at 30 kV from a Pulse-Forming-Network (PFN), yielding a field risetime as short as 60 ns. The fieldstrength was 0.1 T at a current of 1200 A. The modules are made from steel plates and ferrite slabs. The ferrite's high initial outgassing rate presented a serious vacuum problem for a long time.

  11. Peak holding circuit for extremely narrow pulses

    Science.gov (United States)

    Oneill, R. W. (Inventor)

    1975-01-01

    An improved pulse stretching circuit comprising: a high speed wide-band amplifier connected in a fast charge integrator configuration; a holding circuit including a capacitor connected in parallel with a discharging network which employs a resistor and an FET; and an output buffer amplifier. Input pulses of very short duration are applied to the integrator charging the capacitor to a value proportional to the input pulse amplitude. After a predetermined period of time, conventional circuitry generates a dump pulse which is applied to the gate of the FET making a low resistance path to ground which discharges the capacitor. When the dump pulse terminates, the circuit is ready to accept another pulse to be stretched. The very short input pulses are thus stretched in width so that they may be analyzed by conventional pulse height analyzers.

  12. KAJIAN INDUCED PLURIPOTENT STEMCELL (iPS (HARAPAN DAN TANTANGAN

    Directory of Open Access Journals (Sweden)

    Masagus Zainuri

    2014-05-01

    Full Text Available AbstractInduced Pluripotent Stemcell (iPS are adult cells which the genetic information in the nucleus of those cells being reprogrammed (reprogram by inserting exogenous pluripotential genes. The exogenous gene transduction is using vectors, such as lentivirus, retrovirus, or adenovirus, which suppressed the gene expression of the original cells, so they will express the transduced exogenous gene. Viral vectors are then used to reprogramming and producing iPS clones that are pluripotent. iPS derived from adult cells of patient with certain diseases will be used as a tool to study the mechanisms of those specific diseases and the effects of selected drugs against the diseases. Several previous studies have shown that iPS clones developed from specific genetic disease have its original genotype and retain the character of the response to the drug that similar as the original adult cells. Opportunities for the utilization of autologous iPS cell therapy in the future is wide open as expected iPS transplant will not be rejected when transplanted back to the patient. Behind all its potential, iPS production is still facing some problems to be applicable clinically. The use of viruses as vectors may cause problems due to virus gene sequences may be integrated into the genome of the DNA donor cell, thereby causing mutations of the iPS clones. Several subsequent studies have succeeded in replacing the use of viruses as vectors, but the level of efficiency obtained is still very low. Another problem that arises is that epigenetic changes may occur in iPS cultures. Many advanced research related to iPS may be developed in Indonesia and is necessary to improve the production efficiency of iPS and solve iPS clones epigenetic changes problems in the future.Keywords: iPS, pluripotency, transduction, transfection.AbstrakInduced Pluripotent Stemcell (iPS adalah sel somatic dewasa yang informasi genetika dalam inti selnyadiprogram ulang (reprogram dengan cara

  13. Femtosecond pulsed laser processing of electronic materials: Fundamentals and micro/nano-scale applications

    Science.gov (United States)

    Choi, Tae-Youl

    ultrashort laser pulse accompanied by the pre-pulse induces air breakdown that can be detrimental to materials processing. A time-resolved pump-and-probe experiment provides distinct evidence for the occurrence of an air plasma and air breakdown. This highly nonlinear phenomenon takes place before the commencement of the ablation process, which is traced beyond elapsed time of the order of 10 ps with respect to the ablating pulse. The nonlinear refractive index of the generated air plasma is calculated as a function of electron density. The self-focusing of the main pulse is identified by the third order nonlinear susceptibility. A crystalline silicon sample is subjected to two optically separated ultra-fast laser pulses of full-width-half-maximum (FWHM) duration of about 80 femtoseconds. These pulses are delivered at wavelength, lambda = 800 nm. Femtosecond-resolved imaging pump-and-probe experiments in reflective and Schlieren configurations have been performed to investigate plasma dynamics and shock wave propagation during the sample ablation process. By using a diffractive optical element (DOE) for beam shaping, microchannels were fabricated. A super-long working distance objective lens was used to machine silicon materials in the sub-micrometer scale. As an extension of micro-machining, the finite difference time domain (FDTD) method is used to assess the feasibility of using near-field distribution of laser light. Gold coated films were machined with nano-scale dimensions and characterized with atomic force microscopy (AFM).

  14. Anomalous photo-induced response by double-pulse excitation in the organic conductor (EDO-TTF)2PF6

    Science.gov (United States)

    Onda, Ken; Ogihara, Sho; Ishikawa, Tadahiko; Okimoto, Yoichi; Shao, Xiangfeng; Nakano, Yoshiaki; Yamochi, Hideki; Saito, Gunzi; Koshihara, Shin-ya

    2009-02-01

    We measured ultrafast reflectivity changes induced by double-pulse excitation in the organic conductor (EDO-TTF)2PF6. Using double-pulse excitation with a relatively high intensity, the sign of reflectivity change became reversed at around 0.8 ps and subsequently the reflectivity change reverted to that of the normal photo-induced state after about 1 ps. Using a optically phase-locked double-pulse with low intensity, we found that the temporal profile excited by an in-phase double-pulse differs from that by an out-of-phase double-pulse despite the time difference between the double-pulses being only 1.31 fs. This was true even when there is almost no overlap between each pulse in the double-pulse. These results indicate that the photo-response in this material to double-pulse excitation differs greatly from the linear sum of the responses to single pulses.

  15. Femtosecond pulses from a modelocked integrated external-cavity surface emitting laser (MIXSEL).

    Science.gov (United States)

    Mangold, Mario; Wittwer, Valentin J; Zaugg, Christian A; Link, Sandro M; Golling, Matthias; Tilma, Bauke W; Keller, Ursula

    2013-10-21

    Novel surface-emitting optically pumped semiconductor lasers have demonstrated >1 W modelocked and >100 W continuous wave (cw) average output power. The modelocked integrated external-cavity surface emitting laser (MIXSEL) combines the gain of vertical-external-cavity surface-emitting lasers (VECSELs) with the saturable absorber of a semiconductor saturable absorber mirror (SESAM) in one single semiconductor structure. This unique concept allows for stable and self-starting passive modelocking in a simple straight cavity. With quantum-dot based absorbers, record-high average output power was demonstrated previously, however the pulse duration was limited to 17 ps so far. Here, we present the first femtosecond MIXSEL emitting pulses with a duration as short as 620 fs at 4.8 GHz repetition rate and 101 mW average output power. The novel MIXSEL structure relies on a single low temperature grown quantum-well saturable absorber with a low saturation fluence and fast recovery dynamics. A detailed characterization of the key modelocking parameters of the absorber and the challenges for absorber integration into the MIXSEL structure are discussed.

  16. Comparison of molecular species of various transphosphatidylated phosphatidylserine (PS) with bovine cortex PS by mass spectrometry

    NARCIS (Netherlands)

    Chen, S.; Li, K.W.

    2008-01-01

    The exogenous introduction of a molecular species mixture of bovine cortex phosphatidylserine (BC-PS) has been claimed to improve memory function in subjects suffering from age-associated memory impairment and dementia. However, it has been also reported that oral administration of another molecular

  17. Enhancement mechanism of femtosecond double-pulse laser-induced Cu plasma spectroscopy

    Science.gov (United States)

    Zhang, Dan; Chen, Anmin; Wang, Xiaowei; Li, Suyu; Wang, Ying; Sui, Laizhi; Jiang, Yuanfei; Jin, Mingxing

    2017-11-01

    A dual-wavelength femtosecond double-pulse laser is used to induce the Cu plasma spectroscopy in air. The laser wavelengths are a fundamental wavelength (800 nm) and a second harmonic wavelength (400 nm) from Ti:sapphire laser. The inter-pulse delay of double-pulse is from -300 ps to 160 ps. The observed spectral intensity is dependent on the inter-pulse delay of the dual-wavelength femtosecond double-pulse. We analyze the characteristics of the plasma temperature and the electron number density on the inter-pulse delay of double-pulse with two different wavelengths. For 800 nm + 400 nm, the spectral emission enhancement is based on more material ablation. For 400 nm + 800 nm, the enhanced mechanism is plasma reheating effect. This study will provide a better way to understand the mechanism of femtosecond double-pulse LIBS.

  18. Pulse shortening of an ultrafast VECSEL

    Science.gov (United States)

    Waldburger, D.; Alfieri, C. G. E.; Link, S. M.; Gini, E.; Golling, M.; Mangold, M.; Tilma, B. W.; Keller, U.

    2016-03-01

    Ultrafast, optically pumped, passively modelocked vertical external-cavity surface-emitting lasers (VECSELs) are excellent sources for industrial and scientific applications that benefit from compact semiconductor based high-power ultrafast lasers with gigahertz repetition rates and excellent beam quality. Applications such as self-referenced frequency combs and multi-photon imaging require sub-200-fs pulse duration combined with high pulse peak power. Here, we present a semiconductor saturable absorber mirror (SESAM) modelocked VECSEL with a pulse duration of 147 fs and 328 W of pulse peak power. The average output power was 100 mW with a repetition rate of 1.82 GHz at a center wavelength of 1034 nm. The laser has optimal beam quality operating in a fundamental transverse mode with a M2 value of strain-compensated InGaAs quantum wells (QWs). The QWs are placed symmetrical around the antinodes of the standing electric field at a reduced average field enhancement in the QWs of ≈ 0.5 (normalized to 4 outside the structure). These results overcome the trade-off between pulse duration and peak power of the state-of-the-art threshold values of 4.35 kW peak power for a pulse duration of 400 fs and 3.3 W peak power for a pulse duration of 107 fs.

  19. Production of picosecond, kilojoule, petawatt laser pulses via Raman amplification of nanosecond pulses

    CERN Document Server

    Trines, R; Bingham, R; Fonseca, R A; Silva, L O; Cairns, R A; Norreys, P A

    2011-01-01

    Raman amplification in plasma has been promoted as a means of compressing picosecond optical laser pulses to femtosecond duration to explore the intensity frontier. Here we show for the first time that it can be used, with equal success, to compress laser pulses from nanosecond to picosecond duration. Simulations show up to 60% energy transfer from pump to probe pulses, implying that multi-kiloJoule ultra-violet petawatt laser pulses can be produced using this scheme. This has important consequences for the demonstration of fast-ignition inertial confinement fusion.

  20. Pulsed light and pulsed electric field for foods and eggs.

    Science.gov (United States)

    Dunn, J

    1996-09-01

    Two new technologies for use in the food industry are described. The first method discussed uses intense pulse of light. This pulsed light (PureBright) process uses short duration flashes of broad spectrum "white" light to kill all exposed microorganisms, including vegetative bacteria, microbial and fungal spores, viruses, and protozoan oocysts. Each pulse, or flash, of light lasts only a few hundred millionths of a second (i.e., a few hundred microseconds). The intensity of each flash of light is about 20,000 times the intensity of sunlight at the earth's surface. The flashes are typically applied at a rate of about one to tens of flashes per second. For most applications, a few flashes applied in a fraction of a second provide an effective treatment. High microbial kill can be achieved, for example, on the surfaces of packaging materials, on packaging and processing equipment, foods, and medical devices as well as on many other surfaces. In addition, some bulk materials such as water and air that allow penetration of the light can be sterilized. The results of tests to measure the effects of pulsed light on Salmonella enteritiditis on eggs are presented. The second method discussed uses multiple, short duration, high intensity electric field pulses to kill vegetative microorganisms in pumpable products. This pulsed electric field (or CoolPure) process can be applied at modest temperatures at which no appreciable thermal damage occurs and the original taste, color, texture, and functionality of products can be retained.

  1. New pulse modulator with low switching frequency

    Directory of Open Access Journals (Sweden)

    Golub V. S.

    2014-12-01

    Full Text Available The author presents an integrating pulse modulator (analog signal converter with the pulse frequency and duration modulation similar to sigma-delta modulation (with low switching frequency, without quantization. The modulator is characterized by the absence of the quantization noise inherent in sigma-delta modulator, and a low switching frequency, unlike the pulse-frequency modulator. The modulator is recommended, in particular, to convert signals at the input of the class D power amplifier.

  2. Pulsed writing of solid state holograms.

    Science.gov (United States)

    Gaylord, T. K.; Rabson, T. A.; Tittel, F. K.; Quick, C. R.

    1973-01-01

    The pulsed writing of volume holograms in lithium niobate is reported, both with 200-nsec and 20-nsec duration pulses. This information is of particular interest in high capacity information storage applications since it indicates that writing times at least as short as 20-nsec are readily possible. A series of pulses was used in each case, and the diffraction efficiency was monitored using a He-Ne laser operating at 6328 A and aligned to its corresponding Bragg angle.

  3. Deuterium–deuterium nuclear reaction induced by high intensity laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Torrisi, L., E-mail: lorenzo.torrisi@unime.it [INFN-LNS, Via S. Sofia 44, 95123 Catania (Italy); Dip.to di Fisica, Università di Messina, V.le F.S. D’Alcontres 31, 98166 S. Agata, Messina (Italy); Cavallaro, S.; Cutroneo, M.; Giuffrida, L. [INFN-LNS, Via S. Sofia 44, 95123 Catania (Italy); Dip.to di Fisica, Università di Messina, V.le F.S. D’Alcontres 31, 98166 S. Agata, Messina (Italy); Krasa, J.; Margarone, D.; Velyhan, A. [Institute of Physics, ASCR, v.v.i., 182 21 Prague 8 (Czech Republic); Kravarik, J. [Institute of Physics, ASCR, v.v.i., 182 21 Prague 8 (Czech Republic); Czech Technical University, Faculty of Electro-Engineering, Prague (Czech Republic); Ullschmied, J. [Institute of Physics, ASCR, v.v.i., 182 21 Prague 8 (Czech Republic); Wolowski, J.; Szydlowski, A.; Rosinski, M. [Institute of Plasma Physics and Laser Microfusion, IPPLM, 23 Hery Str., 01-497 Warsaw (Poland)

    2013-05-01

    A 10{sup 16} W/cm{sup 2} Asterix laser pulse intensity, 1315 nm wavelength, 300 ps pulse duration, was employed at PALS laboratory of Prague, to irradiate thick and thin primary CD{sub 2} targets placed into the high vacuum chamber. The laser irradiation produces non-equilibrium plasma with deuterons and carbon ions emission with energy up to about 4 MeV per charge state, as measured by time-of-flight (TOF) techniques by using ion collectors and silicon carbide detectors. Accelerated deuterium ions may induce high D–D cross section for fusion processes generating 3 MeV protons and 2.5 MeV neutrons, as measured by TOF analyses. In order to increase the mono-energetic proton yield, secondary CD{sub 2} targets can be availed to be irradiated by the plasma-accelerated deuterons. Experiments demonstrated that high intensity laser pulses can be employed to promote nuclear reactions from which characteristic ion streams may be developed. Results open new scenario for applications of laser-generated plasma to the fields of ion sources and ion accelerators.

  4. Deuterium-deuterium nuclear reaction induced by high intensity laser pulses

    Science.gov (United States)

    Torrisi, L.; Cavallaro, S.; Cutroneo, M.; Giuffrida, L.; Krasa, J.; Margarone, D.; Velyhan, A.; Kravarik, J.; Ullschmied, J.; Wolowski, J.; Szydlowski, A.; Rosinski, M.

    2013-05-01

    A 1016 W/cm2 Asterix laser pulse intensity, 1315 nm wavelength, 300 ps pulse duration, was employed at PALS laboratory of Prague, to irradiate thick and thin primary CD2 targets placed into the high vacuum chamber. The laser irradiation produces non-equilibrium plasma with deuterons and carbon ions emission with energy up to about 4 MeV per charge state, as measured by time-of-flight (TOF) techniques by using ion collectors and silicon carbide detectors. Accelerated deuterium ions may induce high D-D cross section for fusion processes generating 3 MeV protons and 2.5 MeV neutrons, as measured by TOF analyses. In order to increase the mono-energetic proton yield, secondary CD2 targets can be availed to be irradiated by the plasma-accelerated deuterons. Experiments demonstrated that high intensity laser pulses can be employed to promote nuclear reactions from which characteristic ion streams may be developed. Results open new scenario for applications of laser-generated plasma to the fields of ion sources and ion accelerators.

  5. Observations of surface modifications induced by the multiple pulse irradiation using a soft picosecond x-ray laser beam

    Energy Technology Data Exchange (ETDEWEB)

    Ishino, Masahiko; Tanaka, Momoko; Hasegawa, Noboru; Nishikino, Masaharu; Kaihori, Takeshi; Kawachi, Tetsuya [Japan Atomic Energy Agency, Quantum Beam Science Directorate, Kyoto (Japan); Faenov, Anatoly Y.; Pikuz, Tatiana A. [Japan Atomic Energy Agency, Quantum Beam Science Directorate, Kyoto (Japan); Russian Academy of Sciences, Joint Institute for High Temperatures, Moscow (Russian Federation); Tamotsu, Satoshi [Nara Women' s University, Division of Natural Sciences, Faculty, Nara (Japan)

    2013-01-15

    To study the interactions between picosecond soft x-ray laser (SXRL) beams and material surfaces, gold (Au), copper (Cu), and silicon (Si) surfaces were irradiated with SXRL pulses having a wavelength of 13.9 nm and a duration of {proportional_to}7 ps. Following irradiation, the surfaces of the substrates were observed using a scanning electron microscope and an atomic force microscope. With single pulse irradiation, ripple-like structures were formed on the Au and Cu surfaces. These structures were different from previously investigated conical structures formed on an Al surface. In addition, it was confirmed that the development of modified structures, i.e., growth of hillocks on the Au and Cu surfaces, was observed after multiple SXRL pulse exposures. However, on the Si surface, deep holes that seemed to be melted structures induced by the accumulation of multiple pulses of irradiations were found. Therefore, it was concluded that SXRL beam irradiation of various material surfaces causes different types of surface modifications, and the changes in the surface behaviors are attributed to the differences in the elemental properties, such as the attenuation length of x-ray photons. (orig.)

  6. Pulse width shaping of passively mode-locked soliton fiber laser via polarization control in carbon nanotube saturable absorber.

    Science.gov (United States)

    Jeong, Hwanseong; Choi, Sun Young; Rotermund, Fabian; Yeom, Dong-Il

    2013-11-04

    We report the continuous control of the pulse width of a passively mode-locked fiber laser via polarization state adjustment in a single-walled carbon nanotube saturable absorber (SWCNT-SA). The SWCNT, coated on the side-polished fiber, was fabricated with optimized conditions and used for stable mode-locking of the fiber laser without Q-switching instabilities for any polarization state of the laser intra-cavity. The 3-dB spectral bandwidth of the mode-locked pulses can be continuously tuned from 1.8 nm to 8.5 nm with the polarization control for a given laser cavity length and applied pump power. A pulse duration varying from 470 fs to 1.6 ps was also observed with a change in the spectral bandwidth. The linear and the nonlinear transmission properties of the SA were analyzed, and found to exhibit different modulation depths depending on the input polarization state in the SA. The largest modulation depth of the SA was observed at the polarization state of the transverse electric mode that delivers shortest pulses at the laser output.

  7. Pulse Oximetry

    Science.gov (United States)

    ... people need more oxygen when asleep than when awake. Some need more oxygen with activity than when ... oxygen saturation levels (below 80%) or with very dark skin. When should I use a pulse oximeter? ...

  8. Vertical septum magnets for distributing the beam to the 4 PS Booster rings

    CERN Multimedia

    Ordan, Julien Marius

    2017-01-01

    To facilitate H- injection from Linac4 to the PS Booster via the transfer line the BI.SMV10 (Booster Injection Septum Magnet Vertical) provides the vertical deflection of the 160 MeV H- beam to rings 1, 2 and 4 of the Booster. Currently this system is capable of deflecting 50 MeV protons and comprises an assembly of ferrite type magnets in an “omega” section vacuum tank (see fig. 1). The current system shall be replaced with a UHV compatible vacuum chamber incorporating 3 sets of double septum magnets, pulsed from 3 individual power supplies via transformers with 12:1 ratio.

  9. Polarimetry diagnostic on OMEGA EP using a 10-ps, 263-nm probe beam.

    Science.gov (United States)

    Davies, A; Haberberger, D; Boni, R; Ivancic, S; Brown, R; Froula, D H

    2014-11-01

    A polarimetry diagnostic was built and characterized for magnetic-field measurements in laser-plasma experiments on the OMEGA EP laser. This diagnostic was built into the existing 4ω (263-nm) probe system that employs a 10-ps laser pulse collected with an f/4 imaging system. The diagnostic measures the rotation of the probe beam's polarization. The polarimeter uses a Wollaston prism to split the probe beam into orthogonal polarization components. Spatially localized intensity variations between images indicate polarization rotation. Magnetic fields can be calculated by combining the polarimetry data with the measured plasma density profile obtained from angular filter refractometry.

  10. High-throughput gated photon counter with two detection windows programmable down to 70 ps width

    Energy Technology Data Exchange (ETDEWEB)

    Boso, Gianluca; Tosi, Alberto, E-mail: alberto.tosi@polimi.it; Zappa, Franco [Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy); Mora, Alberto Dalla [Dipartimento di Fisica, Politecnico di Milano, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy)

    2014-01-15

    We present the design and characterization of a high-throughput gated photon counter able to count electrical pulses occurring within two well-defined and programmable detection windows. We extensively characterized and validated this instrument up to 100 Mcounts/s and with detection window width down to 70 ps. This instrument is suitable for many applications and proves to be a cost-effective and compact alternative to time-correlated single-photon counting equipment, thanks to its easy configurability, user-friendly interface, and fully adjustable settings via a Universal Serial Bus (USB) link to a remote computer.

  11. A study of ps-laser-induced-damage-threshold in hybrid metal-dielectric mirrors

    Science.gov (United States)

    Škoda, Václav; Vanda, Jan

    2014-10-01

    Laser-induced-damage-threshold of two types of metal-dielectric mirrors was tested using a laser apparatus working at 800 nm wavelength with 1 ps pulse length at 1 kHz repetition rate and in 106-on-1 test mode. Four sets of mirror samples with different layer system designs using a multilayer Ta2O5/SiO2 coating on silver or gold metal layer were manufactured. Both BK7 and fused silica substrate materials were used for manufacturing of samples. The measured damage thresholds at 45 deg incidence and P-polarization were compared with computed properties of layer system and used materials.

  12. Discounted Duration Calculus

    DEFF Research Database (Denmark)

    Ody, Heinrich; Fränzle, Martin; Hansen, Michael Reichhardt

    2016-01-01

    To formally reason about the temporal quality of systems discounting was introduced to CTL and LTL. However, these logic are discrete and they cannot express duration properties. In this work we introduce discounting for a variant of Duration Calculus. We prove decidability of model checking...... for a useful fragment of discounted Duration Calculus formulas on timed automata under mild assumptions. Further, we provide an extensive example to show the usefulness of the fragment....

  13. PS main supply: motor-generator set.

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    In picture 04 the motor is on the right in the background and the main view is of the generator. The peak power in each PS cycle drawn from the generator, up to 96 MW, is taken from the rotational kinetic energy of the rotor (a heavy-weight of 80 tons), which makes the rotational speed drop by only a few percent. The motor replenishes the average power of 2 to 4 MW. Photo 05: The motor-generator set is serviced every year and, in particular, bearings and slip-rings are carefully checked. To the left is the motor with its slip-rings visible. It has been detached from the axle and moved to the side, so that the rotor can be removed from the huge generator, looming at the right.

  14. Behavioural Phenotyping of APPswe/PS1δE9 Mice

    DEFF Research Database (Denmark)

    Olesen, Louise Ørum; Bouzinova, Elena V; Severino, Maurizio

    2016-01-01

    Alzheimer's disease (AD) is a devastating illness characterized by a progressive loss of cognitive, social, and emotional functions, including memory impairments and more global cognitive deficits. Clinical-epidemiological evidence suggests that neuropsychiatric symptoms precede the onset......-cognitive behavioural changes measured at 9, 12, 15, and 18 months of age and applied principal component analysis on data obtained from open field, elevated plus maze, and social interaction tests. Long-term treatment with the selective serotonin reuptake inhibitor (SSRI) paroxetine was applied to assess the role of 5......-HT on the behavioural profile; duration of treatment was 9 months, initiated when mice were 9 months of age. Treatment with paroxetine delays the decline in locomotion, in exploration and risk assessment behaviour, found in the APP/PS1 mice. APP/PS1 mice also exhibit low social activity and less...

  15. High-speed pulse train amplification in semiconductor optical amplifiers with optimized bias current

    OpenAIRE

    Xia, Mingjun; H. Ghafouri-Shiraz; Hou, Lianping; Kelly, Anthony E.

    2017-01-01

    In this paper, we have experimentally investigated the optimized bias current of semiconductor optical amplifiers (SOAs) to achieve high-speed input pulse train amplification with high gain and low distortion. Variations of the amplified output pulse duration with the amplifier bias currents have been analyzed and, compared to the input pulse duration, the amplified output pulse duration is broadened. As the SOA bias current decreases from the high level (larger than the saturated bias curren...

  16. Efficacy of ipl in treatment of acne vulgaris : comparison of single- and burst-pulse mode in ipl

    National Research Council Canada - National Science Library

    Kumaresan, M; Srinivas, C R

    2010-01-01

    Intense pulsed light (IPL) has been used for the treatment of facial acne. Modifications of various parameters allow flexibility in treatment, which include energy fluence, pulse duration, and pulse delay...

  17. Few-cycle high energy mid-infrared pulse from Ho:YLF laser

    Energy Technology Data Exchange (ETDEWEB)

    Murari, Krishna

    2017-04-15

    Over the past decade, development of high-energy ultrafast laser sources has led to important breakthroughs in attoscience and strong-field physics study in atoms and molecules. Coherent pulse synthesis of few-cycle high-energy laser pulse is a promising tool to generate isolated attosecond pulses via high harmonics generation (HHG). An effective way to extend the HHG cut-off energy to higher values is making use of long mid-infrared (MIR) driver wavelength, as the ponderomotive potential scales quadratically with wavelength. If properly scaled in energy to multi-mJ level and few-cycle duration, such pulses provide a direct path to intriguing attoscience experiments in gases and solids, which even permit the realization of bright coherent table-top HHG sources in the water-window and keV X-ray region. However, the generation of high-intensity long-wavelength MIR pulses has always remained challenging, in particular starting from high-energy picosecond 2-μm laser driver, that is suitable for further energy scaling of the MIR pulses to multi-mJ energies by utilizing optical parametric amplifiers (OPAs). In this thesis, a front-end source for such MIR OPA is presented. In particular, a novel and robust strong-field few-cycle 2-μm laser driver directly from picosecond Ho:YLF laser and utilizing Kagome fiber based compression is presented. We achieved: a 70-fold compression of 140-μJ, 3.3-ps pulses from Ho:YLF amplifier to 48 fs with 11 μJ energy. The work presented in this thesis demonstrates a straightforward path towards generation of few-cycle MIR pulses and we believe that in the future the ultrafast community will benefit from this enabling technology. The results are summarized in mainly four parts: The first part is focused on the development of a 2-μm, high-energy laser source as the front-end. Comparison of available technology in general and promising gain media at MIR wavelength are discussed. Starting from the basics of an OPA, the design criteria

  18. Material processing with ultra-short pulse lasers working in 2μm wavelength range

    Science.gov (United States)

    Voisiat, B.; Gaponov, D.; Gečys, P.; Lavoute, L.; Silva, M.; Hideur, A.; Ducros, N.; Račiukaitis, G.

    2015-03-01

    New wavelengths of laser radiation are of interest for material processing. Results of application of the all-fiber ultrashort pulsed laser emitting in 2 µm range, manufactured by Novae, are presented. Average output power was 4.35 W in a single-spatial-mode beam centered at the 1950 nm wavelength. Pulses duration was 40 ps, and laser operated at 4.2 MHz pulse repetition rate. This performance corresponded to 25 kW of pulse peak power and almost 1 µJ in pulse energy. Material processing was performed using three different focusing lenses (100, 30 and 18 mm) and mechanical stages for the workpiece translation. 2 µm laser radiation is strongly absorbed by some polymers. Swelling of PMMA surface was observed for scanning speed above 5 mm/s using the average power of 3.45 W focused with the 30 mm lens. When scanning speed was reduced below 4 mm/s, ablation of PMMA took place. The swelling of PMMA is a consequence of its melting due to absorbed laser power. Therefore, experiments on butt welding of PMMA and overlapping welding of PMMA with other polymers were performed. Stable joint was achieved for the butt welding of two PMMA blocks with thickness of 5 mm. The laser was used to cut a Kapton film on a paper carrier with the same set-up as previous. The cut width depended on the cutting speed and focusing optics. A perfect cut with a width of 11 µm was achieved at the translation speed of 60 mm/s.

  19. PS: A nonprocedural language with data types and modules

    Science.gov (United States)

    Gokhale, M. B.

    1986-01-01

    The Problem Specification (PS) nonprocedural language is a very high level language for algorithm specification. PS is suitable for nonprogrammers, who can specify a problem using mathematically-oriented equations; for expert programmers, who can prototype different versions of a software system for evaluation; and for those who wish to use specifications for portions (if not all) of a program. PS has data types and modules similar to Modula-2. The compiler generates C code. PS is first shown by example, and then efficiency issues in scheduling and code generation are discussed.

  20. Distinct iPS Cells Show Different Cardiac Differentiation Efficiency.

    Science.gov (United States)

    Ohno, Yohei; Yuasa, Shinsuke; Egashira, Toru; Seki, Tomohisa; Hashimoto, Hisayuki; Tohyama, Shugo; Saito, Yuki; Kunitomi, Akira; Shimoji, Kenichiro; Onizuka, Takeshi; Kageyama, Toshimi; Yae, Kojiro; Tanaka, Tomofumi; Kaneda, Ruri; Hattori, Fumiyuki; Murata, Mitsushige; Kimura, Kensuke; Fukuda, Keiichi

    2013-01-01

    Patient-specific induced pluripotent stem (iPS) cells can be generated by introducing transcription factors that are highly expressed in embryonic stem (ES) cells into somatic cells. This opens up new possibilities for cell transplantation-based regenerative medicine by overcoming the ethical issues and immunological problems associated with ES cells. Despite the development of various methods for the generation of iPS cells that have resulted in increased efficiency, safety, and general versatility, it remains unknown which types of iPS cells are suitable for clinical use. Therefore, the aims of the present study were to assess (1) the differentiation potential, time course, and efficiency of different types of iPS cell lines to differentiate into cardiomyocytes in vitro and (2) the properties of the iPS cell-derived cardiomyocytes. We found that high-quality iPS cells exhibited better cardiomyocyte differentiation in terms of the time course and efficiency of differentiation than low-quality iPS cells, which hardly ever differentiated into cardiomyocytes. Because of the different properties of the various iPS cell lines such as cardiac differentiation efficiency and potential safety hazards, newly established iPS cell lines must be characterized prior to their use in cardiac regenerative medicine.

  1. Neural substrate for brain stimulation reward in the rat: cathodal and anodal strength-duration properties.

    Science.gov (United States)

    Matthews, G

    1977-08-01

    The trade-off between current strength and duration of a stimulating pulse was studied for the rewarding and priming effects of brain stimulation reward (BSR). With cathodal pulses, strenght-duration functions for BSR had chronaxies of .8-3 msec. No differences were observed between the results for rewarding and priming effects. With anodal pulses. strength-duration curves were parallel to the cathodal curves at pulse durations of .1-5 msec, but at pulse durations greater than 5 msec the anodal curves showed a greater drop in required current intensity than did the cathodal curves. The parallel portion of the anodal curves was interpreted as due to anode-make excitation, and the drop at longer pulse durations was interpreted as due to anode-break excitation. Cathodal strength-duration functions for the motor effect elicited through the BSR electrodes had chronaxies of .15-.48 msec. Measurements of the latency of the muscle twitch confirmed that anode-make and anode-break excitation occurred, the latter becoming evident at pulse durations as brief as .3-.4 msec. The results provide quantitative characterization of cathodal and anodal strength-duration properties of the neural substrate for BSR and are discussed in terms of their value in guiding electrophysiological investigation of that substrate.

  2. Picosecond imaging of inertial confinement fusion plasmas using electron pulse-dilation

    Science.gov (United States)

    Hilsabeck, T. J.; Nagel, S. R.; Hares, J. D.; Kilkenny, J. D.; Bell, P. M.; Bradley, D. K.; Dymoke-Bradshaw, A. K. L.; Piston, K.; Chung, T. M.

    2017-02-01

    Laser driven inertial confinement fusion (ICF) plasmas typically have burn durations on the order of 100 ps. Time resolved imaging of the x-ray self emission during the hot spot formation is an important diagnostic tool which gives information on implosion symmetry, transient features and stagnation time. Traditional x-ray gated imagers for ICF use microchannel plate detectors to obtain gate widths of 40-100 ps. The development of electron pulse-dilation imaging has enabled a 10X improvement in temporal resolution over legacy instruments. In this technique, the incoming x-ray image is converted to electrons at a photocathode. The electrons are accelerated with a time-varying potential that leads to temporal expansion as the electron signal transits the tube. This expanded signal is recorded with a gated detector and the effective temporal resolution of the composite system can be as low as several picoseconds. An instrument based on this principle, known as the Dilation X-ray Imager (DIXI) has been constructed and fielded at the National Ignition Facility. Design features and experimental results from DIXI will be presented.

  3. Description of pulse propagation in a dispersive medium by use of a pulse quality factor.

    Science.gov (United States)

    Rousseau, Guy; McCarthy, Nathalie; Pichãé, Michel

    2002-09-15

    We investigated how the duration of short laser pulses evolves in a dispersive material, using rms widths and a propagation law based on a pulse quality factor. Experiments were carried out with femtosecond pulses (10 to 25fs at the temporal waist) propagating in bulk fused silica. Excellent agreement was found between theory and experiment. This approach does not require complete characterization of laser pulses and eliminates the need for any assumption regarding the interpretation of autocorrelation traces. The method is of general validity, and it can be applied to pulses of arbitrary shape.

  4. The 1.4 GeV PS Booster in its tunnel.

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    The PS Improvement Programme, launched as early as 1964, had a "Booster" as the key element in the quest for higher beam intensity and density. These were limited in the PS at injection of the 50 MeV proton beam from the linac by the incoherent (Laslett-) Q-shift. Boosting the linac beam to 800 MeV would raise the PS intensity limit by an order of magnitude, from 1E12 protons per pulse to 1E13. The main motivation was the supply of intense beams to the ISR. Soon, the Booster proved to be crucial for the neutral current experiment. A unique feature of the Booster are its 4 superposed rings. Its lattice is also unusual: between its 32 bending magnets, every second straight section contains a quadrupole triplet (F,D,F), while the alternate ones are drift spaces (mostly filled with essential components like septa, kickers, RF-cavities, etc.). In each picture we see one of the 16 periods. Following the direction of the beam from right to left: a bending magnet (green); an empty straight section; a bending magnet; ...

  5. Pulse plating

    CERN Document Server

    Hansal, Wolfgang E G; Green, Todd; Leisner, Peter; Reichenbach, Andreas

    2012-01-01

    The electrodeposition of metals using pulsed current has achieved practical importance in recent years. Although it has long been known that changes in potential, with or without polarity reversal, can significantly affect the deposition process, the practical application of this has been slow to be adopted. This can largely be explained in terms of the complex relationship between the current regime and its effect on the electrodeposition process. In order to harness these effects, an understanding of the anodic and cathodic electrochemical processes is necessary, together with the effects of polarity reversal and the rate of such reversals. In this new monograph, the basics of metal electrodeposition from solution are laid out in great detail in seven distinct chapters. With this knowledge, the reader is able to predict how a given pulse train profile can be adopted to achieve a desired outcome. Equally important is the choice of a suitable rectifier and the ancillary control circuits to enable pulse platin...

  6. LEADIR-PS: providing unprecedented SMR safety and economics

    Energy Technology Data Exchange (ETDEWEB)

    Hart, R.S., E-mail: N2i2@xplornet.ca [Northern Nuclear Industries Incorporated, Cambridge, ON (Canada)

    2015-07-01

    Northern Nuclear Industries Incorporated (N{sup 2} I{sup 2}) is developing Small Modular Reactors (SMRs) called LEADIR-PS, an acronym for LEAD-cooled Integral Reactor-Passively Safe. LEADIR-PS integrates proven technologies including TRISO fuel, Pebble Bed core and graphite moderator, with molten lead coolant in an integral pool type reactor configuration to achieve unprecedented safety and economics. Plants under development are LEADIR-PS30, producing 30 MWth, LEADIR-PS100 producing 100 MWth and LEADIR-PS300 producing 300 MWth that are focused on serving the energy demands of areas with a small electrical grid and/or process heat applications. A plant consisting of six LEADIR-PS300 reactor modules serving a common turbine-generator, called the LEADIR-PS Six-Pack, is focused on serving areas with higher energy demands and a robust electricity grid. The Gen{sup +} I LEADIR-PS plants are inherently/passively safe. There is no potential for a Loss Of Coolant Accident, a reactivity transient without shutdown, a loss of heat sink, or hydrogen generation. No active systems or operator actions are required to assure safety. The unprecedented safety of LEADIR-PS reactors avoids large exclusion radius and demanding evacuation plan requirements. LEADIR-PS, with steam conditions of 370 {sup o}C and 12 MPa can serve over 85% of the world's non-transportation process heat demands. In Canada, the electricity and process heat demands, ranging from those of remote communities and the oil sands to densely populated areas can be served by LEADIR-PS. (author)

  7. 80 GHz AlGaInAs/InP colliding-pulse mode-locked laser with high pulse power

    Science.gov (United States)

    Zhao, Pengchao; Liu, Anjin; Zheng, Wanhua

    2016-12-01

    We theoretically analyze the impact of a saturable absorber (SA) length on the pulse power of a semiconductor mode-locked laser and find that in the range of the SA length from 1.5 to 7%, a laser with a longer SA can generate pulses with a higher power. Based on the simulation, we demonstrate a colliding-pulse mode-locked laser with an 80 µm SA. The device generates pulses at 80 GHz, with a pulse width of 1.75 ps, peak power of 188 mW, pulse energy of 0.33 pJ, and time-bandwidth product of 0.51. The results provide new possibilities for the design of high-repetition frequency high-pulse power mode-locked lasers.

  8. [Sleep duration and metabolism].

    Science.gov (United States)

    Viot-Blanc, V

    2015-12-01

    Sleep duration has gradually diminished during the last decade while obesity and type 2 diabetes have become epidemics. Experimental sleep curtailment leads to increased appetite, hormonal disturbances and, especially, insulin resistance. Numerous epidemiological studies have therefore examined whether habitual short sleep is associated with obesity and type 2 diabetes. A large majority of cross-sectional studies have confirmed an association between short, and also long sleep duration and obesity in adults more than in the elderly. Short sleep is strongly associated to obesity in children and adolescents. Prospective studies, including studies in children, are not conclusive with regard to the effect of short sleep on the incidence of obesity. Both short and long sleep durations are associated with diabetes, but only short sleep duration seems predictive of future diabetes. Insomnia seems to be a strong contributor to short sleep duration but the association of insomnia with obesity is not clear. Insomnia is associated with type 2 diabetes and also predictive of a higher incidence. Other studies have shown that short sleep duration and insomnia are associated with, and sometime predictive of, other components of the metabolic syndrome, especially hypertension and the risk of coronary disease. The treatment of short sleep duration and insomnia with regard to their effects on the metabolic syndrome merits further study. Copyright © 2015 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  9. Single attosecond pulse production with an ellipticity-modulated driving IR pulse

    Energy Technology Data Exchange (ETDEWEB)

    Strelkov, V [CELIA, Universite Bordeaux 1, 351 Cours de la liberation, 33405 Talence (France); Zair, A [CELIA, Universite Bordeaux 1, 351 Cours de la liberation, 33405 Talence (France); Tcherbakoff, O [CELIA, Universite Bordeaux 1, 351 Cours de la liberation, 33405 Talence (France); Lopez-Martens, R [Department of Physics, Lund Institute of Technology, PO Box 118, S-22100, Lund (Sweden); Cormier, E [CELIA, Universite Bordeaux 1, 351 Cours de la liberation, 33405 Talence (France); Mevel, E [CELIA, Universite Bordeaux 1, 351 Cours de la liberation, 33405 Talence (France); Constant, E [CELIA, Universite Bordeaux 1, 351 Cours de la liberation, 33405 Talence (France)

    2005-05-28

    We theoretically study attosecond pulse production via high-harmonic generation using a driving laser pulse with a time-dependent ellipticity. The theoretical approach produces results that agree with our experimental data obtained using 35 fs driving laser pulses and is further used to study the generation of single attosecond pulses with shorter laser pulses. We find an equation for the duration of the temporal window created by the time-varying driving laser polarization in which high-harmonic emission can occur. We formulate the necessary requirements concerning the driving laser field in order to confine the high-harmonic emission in the form of a single attosecond pulse. Indeed, we show that using incident 12 fs laser pulses single attosecond pulses can be produced for certain carrier-envelope phase (CEP) values of the driving pulse. For 6 fs incident laser pulses, single attosecond pulses are produced for all values of the CEP (the intensity of the attosecond pulse still depends on the actual value of the CEP). If implemented with state-of-the-art 5 fs laser pulses, this technique can even lead to the production of sub-100 as pulses. (letter to the editor)

  10. The HARP detector at the CERN PS

    CERN Document Server

    Catanesi, M G; Radicioni, E; Simone, S; Edgecock, R; Ellis, M; Robbins, S; Soler, F J P; Gößling, C; Mass, M; Bunyatov, S; Chukanov, A; Klimov, O; Krasin, I; Krasnoperov, A; Kustov, D; Popov, B; Serdiouk, V; Tereshchenko, V; Carassiti, V; Di Capua, E; Evangelisti, F; Vidal-Sitjes, G; Artamonov, A; Arce, P; Brocard, R; Decreuse, G; Friend, B; Giani, S; Gilardoni, S; Gorbunov, p; Grant, A; Grossheim, A; Gruber, P; Ivanchenko, V; Legrand, J C; Kayis-Topaksu,A; Panman, P; Papadopoulos, I; Pasternak, J; Chernyaev, E; Tsukerman, I; van der Vlugt, R; Veenhof, R; Wiebusch, C; Zucchelli, P; Blondel, A; Borghi, S; Campanelli, M; Cervera-Villanueva, A; Morone, M C; Prior, G; Schroeter, R; Kato, I; Gastaldi, Ugo; Mills, G B; Graulich, J S; Grégoire, G; Bonesini, M; Chignoli, F; Ferri, F; Paleari, F; Kirsanov, M; Postoev, V; Bagulya A; Grichine, V; Polukhina, N; Palladino, V; Coney, L; Schmitz, D; Barr, G; De Santo, A; Pattison, C; Zuber, K; Barichello, G; Bobisut, F; Gibin, D; Guglielmi, A; Laveder, M; Menegolli, A; Mezzetto M; Pepato, Adriano; Dumarchez, J; Troquereau, S; Vannucci, F; Dore, U; Iaciofano, A; Lobello, M; Marinilli, F; Orestano, D; Panayotov, D; Pasquali, M; Pastore, F; Tonazzo, A; Tortora, L; Booth, C; Buttar, C; Hodgson, P; Howlett, L; Nicholson, R; Bogomilovw, M; Burin, K; Chizhov, M; Kolev, D; Petev, P; Rusinov, I; Tsenov, R; Piperov, S; Temnikov, P; Apollonio, M; Chimenti, P; Giannini, G; Santin, G; Burguet-Castell, J; Gómez-Cadenas, J J; Novella, P; Sorel, M; Tornero, A

    2007-01-01

    HARP is a high-statistics, large solid angle experiment to measure hadron production using proton and pion beams with momenta between 1.5 and 15 GeV/c impinging on many different solid and liquid targets from low to high Z. The experiment, located in the T9 beam of the CERN PS, took data in 2001 and 2002. For the measurement of momenta of produced particles and for the identification of particle types, the experiment includes a large-angle spectrometer, based on a Time Projection Chamber and a system of Resistive Plate Chambers, and a forward spectrometer equipped with a set of large drift chambers, a threshold Cherenkov detector, a time-of-flight wall and an electromagnetic calorimeter. The large angle system uses a solenoidal magnet, while the forward spectrometer is based on a dipole magnet. Redundancy in particle identification has been sought, to enable the cross-calibration of efficiencies and to obtain a few percent overall accuracy in the cross-section measurements. Detector construction, operation an...

  11. Upconversion imaging using short-wave infrared picosecond pulses

    DEFF Research Database (Denmark)

    Mathez, Morgan David; Rodrigo, Peter John; Tidemand-Lichtenberg, Peter

    2017-01-01

    To the best of our knowledge, we present the first demonstration of short-wavelength infrared image upconversion that employs intense picosecond signal and pump beams. We use a fiber laser that emits a signal beam at 1877 nm and a pump beam at 1550 nm—both with a pulse width of 1 ps and a pulse...... by an improved model that considers the combined image blurring effect due to finite pump beam size, thick nonlinear crystal, and polychromatic infrared illumination....

  12. New Control Structure of the 10 MHz RF System in the CERN PS

    CERN Document Server

    Damerau, H

    2013-01-01

    The 10MHz cavities comprise the main RF system in the CERN PS and the only one that allows acceleration. In total 11 tunable cavities (10 operational and a hot spare, grouped into 3+1 tuning groups and up to presently 6 voltage program groups) are distributed all around the circumference of the PS ring. Next to the RF drive signal each of the cavities is controlled by a voltage program and timing pulses to open and close the relays to short-circuit the cavity gaps. These control signals are presently generated by a dedicated hardware matrix. It translates voltage functions and relay timing pulses per cavity group into functions and timings per cavity. However, due to its central position in the RF beam control system, the dedicated hardware matrix can cause significant downtime in case of a major hardware failure. Instead of upgrading the existing obsolete hardware, this note suggests a replacement by standard controls hardware and dedicated application software. Thanks to advanced software concepts like “M...

  13. Ultra-flat and ultra-broadband supercontinuum generation in photonic crystal fiber pumped by noise-like pulses

    Science.gov (United States)

    Chen, Yewang; Ruan, Shuangchen; Wu, Xu; Guo, Chunyu; Liu, Weiqi; Yu, Jun; Luo, Ruoheng; Ren, Xikui; Zhu, Yihuai

    2017-02-01

    An ultra-flat and ultra-broadband supercontinuum (SC) is demonstrated in a 4-m photonic crystal fiber (PCF) pumped by an Yb-doped all-fiber noise-like pulses (NLP) laser. The Yb-doped fiber laser is seeded by a SESAM mode-locked fiber laser, and amplified by cascaded fiber amplifiers, with its center wavelength, repetition frequency and the average noise-like bunch duration of 1064.52 nm, 50.18 MHz, 9.14 ps, respectively. Pumped by this NLP laser, the SC source has a 3 dB bandwidth and a 7 dB bandwidth (ignore the pump residue) of 1440 nm and 1790 nm at the maximum average output power of 6.94 W. To the best of our knowledge, this flatness is significantly prominent for the performance of PCF-based SC sources.

  14. Very low electron temperature in warm dense matter formed by focused picosecond soft x-ray laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Ishino, Masahiko, E-mail: ishino.masahiko@jaea.go.jp; Hasegawa, Noboru; Nishikino, Masaharu; Kawachi, Tetsuya; Yamagiwa, Mitsuru [Quantum Beam Science Center, Japan Atomic Energy Agency, 8-1-7, Umemidai, Kizugawa, Kyoto 619-0215 (Japan); Pikuz, Tatiana [Joint Institute for High Temperatures, Russian Academy of Sciences, 13-2, Izhorskaya Street, Moscow 125412 (Russian Federation); Graduate School of Engineering, Osaka University, 1-1, Yamadaoka, Suita, Osaka 565-0871 (Japan); Skobelev, Igor [Joint Institute for High Temperatures, Russian Academy of Sciences, 13-2, Izhorskaya Street, Moscow 125412 (Russian Federation); National Research Nuclear University, Moscow Engineering Physics Institute, 31, Kashirskoe Shosse, Moscow 115409 (Russian Federation); Faenov, Anatoly [Joint Institute for High Temperatures, Russian Academy of Sciences, 13-2, Izhorskaya Street, Moscow 125412 (Russian Federation); Institute for Academic Initiatives, Osaka University, 1-1, Yamadaoka, Suita, Osaka 565-0871 (Japan); Inogamov, Nail [Landau Institute for Theoretical Physics, Russian Academy of Sciences, 1-A, Akademika Semenova av., Chernogolovka, Moscow Region 142432 (Russian Federation)

    2014-11-14

    We investigated the optical emission from the ablating surfaces induced by the irradiations of soft x-ray laser (SXRL) pulses with the aim of estimation of the maximum electron temperature. No emission signal in the spectral range of 400–800 nm could be observed despite the formation of damage structures on the target surfaces. Hence, we estimated an upper limit for the electron temperature of 0.4–0.7 eV for the process duration of 100–1000 ps. Our results imply that the ablation and/or surface modification by the SXRL is not accompanied by plasma formation but is induced by thermo-mechanical pressure, which is so called a spallative ablation. This spallative ablation process occurs in the low electron temperature region of a non-equilibrium state of warm dense matter.

  15. Interleaving of beam lines inside the PS tunnel

    CERN Multimedia

    1983-01-01

    View against the direction of the proton beams. The PS ring (section 26) is on the left. The injection tunnel for LEAR leaving from here has increased the trafic in this already busy area where the two Linacs and the transfer tunnel leading to the SPS, ISR and AA join the PS ring (cf. photo 7802260, 7802261, Annual Report 1981, p. 89, fig. 12).

  16. Modulation of enzymatic PS synthesis by liposome membrane composition.

    Science.gov (United States)

    Pinsolle, Alexandre; Roy, Philippe; Cansell, Maud

    2014-03-01

    Phosphatidylserine (PS) is a phospholipid known to exert important physiological roles in humans. However, this phospholipid (PL) is poorly available as a natural source and hardly produced by the chemical route. In this work, PS was obtained by transphosphatidylation using phospholipase D (PLD) and PL self-assembled into liposomes as the substrates. The aim was to better understand how the liposome membrane composition could modulate PS yield. Three lecithins were used as PL substrates, one originated from a marine source providing a high amount of n-3 polyunsaturated fatty acids, and two issued from soya differing in their phosphatidylcholine (PC) content. Different parameters such as Ca(2+) content, enzyme and L-serine concentrations modulated PS synthesis. The presence of Ca(2+) increased PS conversion yield. The alcohol acceptor (L-serine) concentration positively acted on PL conversion, by governing the equilibrium between transphosphatidylation and hydrolysis. Beside these specific reaction conditions, it was demonstrated that the membrane composition of the liposomes modulated PS synthesis. A direct correlation between PS accumulation and the amount of cholesterol or α-tocopherol incorporated into the soya lecithins was observed. This result was interpreted in terms of "head" spacers promoting PLD transphosphatidylation. On the whole, this work provided key parameters for the formulation of liposomes using enzymatic PLD technology, to produce lecithins enriched in different proportions of PS and esterified with various types of fatty acids depending on the initial lecithin source. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. Spectroscopic Classification of PS16chs with SOAR/Goodman

    Science.gov (United States)

    Miller, J. A.; Hounsell, R. A.; Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-05-01

    We report the classification of PS16chs from spectroscopic observation with the Goodman spectrograph on the SOAR telescope. The observation was made on 2016 May 08 UT. We classify PS16chs as a SN Ia near maximum light at z = 0.19.

  18. Transfer line TT70 (electrons from PS to SPS)

    CERN Multimedia

    CERN PhotoLab

    1981-01-01

    As injectors for LEP, PS and SPS had to be converted to the acceleration of electrons and positrons. So far, only positively charged particles had been transferred from the PS to the SPS, for the negatively charged electrons a new transfer line, TT70, had to be built. Due to the difference in level of the two machines, the transfer line slopes and tilts.

  19. Psühhodraama - spontaansuse kool / Taimi Elenurm

    Index Scriptorium Estoniae

    Elenurm, Taimi

    2010-01-01

    Viinis ja New Yorgis tegutsenud psühhiaatri Jakob Levy Moreno loodud psühhodraamast, mis võimaldab rollimängu kaudu näha ennast läbi teiste silmade, aga ka vabaneda pingetest andes võimaluse käituda teisiti kui tavaelus

  20. Loss of GABAergic inputs in APP/PS1 mouse model of Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Tutu Oyelami

    2014-04-01

    Full Text Available Alzheimer's disease (AD is characterized by symptoms which include seizures, sleep disruption, loss of memory as well as anxiety in patients. Of particular importance is the possibility of preventing the progressive loss of neuronal projections in the disease. Transgenic mice overexpressing EOFAD mutant PS1 (L166P and mutant APP (APP KM670/671NL Swedish (APP/PS1 develop a very early and robust Amyloid pathology and display synaptic plasticity impairments and cognitive dysfunction. Here we investigated GABAergic neurotransmission, using multi-electrode array (MEA technology and pharmacological manipulation to quantify the effect of GABA Blockers on field excitatory postsynaptic potentials (fEPSP, and immunostaining of GABAergic neurons. Using MEA technology we confirm impaired LTP induction by high frequency stimulation in APPPS1 hippocampal CA1 region that was associated with reduced alteration of the pair pulse ratio after LTP induction. Synaptic dysfunction was also observed under manipulation of external Calcium concentration and input-output curve. Electrophysiological recordings from brain slice of CA1 hippocampus area, in the presence of GABAergic receptors blockers cocktails further demonstrated significant reduction in the GABAergic inputs in APP/PS1 mice. Moreover, immunostaining of GAD65 a specific marker for GABAergic neurons revealed reduction of the GABAergic inputs in CA1 area of the hippocampus. These results might be linked to increased seizure sensitivity, premature death and cognitive dysfunction in this animal model of AD. Further in depth analysis of GABAergic dysfunction in APP/PS1 mice is required and may open new perspectives for AD therapy by restoring GABAergic function.

  1. Successful online learning – the five Ps

    Directory of Open Access Journals (Sweden)

    Jim FLOOD

    2004-04-01

    Full Text Available Successful online learning – the five Ps Jim FLOOD E-learning Consultant-UK jimflood@btinternet.com Key learning points • An important aspect of design for online learning is visual ergonomics. • Learning theories offer poor predictive power in terms of how learners work and learn. • Success at learning is closely related to emotional engagement–and learning designers tend to ignore this aspect. • Online learning poses a challenging experience for learners–and they need support to cope with it. • A key goal to achieve Praxis – being able to put learning into practice. Many of you will be familiar with the three (or more Ps of marketing and even if not, as trainers or teachers you are likely to have used mnemonics as an aid to retention and recall. Mnemonics are especially useful when you need to get the key points to ‘stick’ in the minds of your audience. With this in mind I offer you the 5 Ps of online learning: Presentation, Pedagogy, Promotion, Preparation and Props. What I offer is not new; in fact much of it results from the eleven years of online teaching and learning at The Open University, the £22 million it has spent on research and evaluation 1, and the worldwide community that have been sharing experience in recent years. You can therefore consider these 5 Ps to be a convenient re-packing of the information and experience that can be found in abundance on the Internet. Presentation Good graphic design appeals to the subtle process by which the brain processes information and, as a result, we decide if we like the ‘look and feel’ of a visual environment. Part of liking this ‘look and feel’ is the way the text and pictorial layout can appear inviting and encouraging–a vital aspect of any online learning environment. Another aspect of presentation is how the text reads in terms of engaging the learner and introducing the story to be told–as well as being written in clear and concise English When browsing through books

  2. Telomere reprogramming and maintenance in porcine iPS cells.

    Directory of Open Access Journals (Sweden)

    Guangzhen Ji

    Full Text Available Telomere reprogramming and silencing of exogenous genes have been demonstrated in mouse and human induced pluripotent stem cells (iPS cells. Pigs have the potential to provide xenotransplant for humans, and to model and test human diseases. We investigated the telomere length and maintenance in porcine iPS cells generated and cultured under various conditions. Telomere lengths vary among different porcine iPS cell lines, some with telomere elongation and maintenance, and others telomere shortening. Porcine iPS cells with sufficient telomere length maintenance show the ability to differentiate in vivo by teratoma formation test. IPS cells with short or dysfunctional telomeres exhibit reduced ability to form teratomas. Moreover, insufficient telomerase and incomplete telomere reprogramming and/or maintenance link to sustained activation of exogenous genes in porcine iPS cells. In contrast, porcine iPS cells with reduced expression of exogenous genes or partial exogene silencing exhibit insufficient activation of endogenous pluripotent genes and telomerase genes, accompanied by telomere shortening with increasing passages. Moreover, telomere doublets, telomere sister chromatid exchanges and t-circles that presumably are involved in telomere lengthening by recombination also are found in porcine iPS cells. These data suggest that both telomerase-dependent and telomerase-independent mechanisms are involved in telomere reprogramming during induction and passages of porcine iPS cells, but these are insufficient, resulting in increased telomere damage and shortening, and chromosomal instability. Active exogenes might compensate for insufficient activation of endogenous genes and incomplete telomere reprogramming and maintenance of porcine iPS cells. Further understanding of telomere reprogramming and maintenance may help improve the quality of porcine iPS cells.

  3. Telomere reprogramming and maintenance in porcine iPS cells.

    Science.gov (United States)

    Ji, Guangzhen; Ruan, Weimin; Liu, Kai; Wang, Fang; Sakellariou, Despoina; Chen, Jijun; Yang, Yang; Okuka, Maja; Han, Jianyong; Liu, Zhonghua; Lai, Liangxue; Gagos, Sarantis; Xiao, Lei; Deng, Hongkui; Li, Ning; Liu, Lin

    2013-01-01

    Telomere reprogramming and silencing of exogenous genes have been demonstrated in mouse and human induced pluripotent stem cells (iPS cells). Pigs have the potential to provide xenotransplant for humans, and to model and test human diseases. We investigated the telomere length and maintenance in porcine iPS cells generated and cultured under various conditions. Telomere lengths vary among different porcine iPS cell lines, some with telomere elongation and maintenance, and others telomere shortening. Porcine iPS cells with sufficient telomere length maintenance show the ability to differentiate in vivo by teratoma formation test. IPS cells with short or dysfunctional telomeres exhibit reduced ability to form teratomas. Moreover, insufficient telomerase and incomplete telomere reprogramming and/or maintenance link to sustained activation of exogenous genes in porcine iPS cells. In contrast, porcine iPS cells with reduced expression of exogenous genes or partial exogene silencing exhibit insufficient activation of endogenous pluripotent genes and telomerase genes, accompanied by telomere shortening with increasing passages. Moreover, telomere doublets, telomere sister chromatid exchanges and t-circles that presumably are involved in telomere lengthening by recombination also are found in porcine iPS cells. These data suggest that both telomerase-dependent and telomerase-independent mechanisms are involved in telomere reprogramming during induction and passages of porcine iPS cells, but these are insufficient, resulting in increased telomere damage and shortening, and chromosomal instability. Active exogenes might compensate for insufficient activation of endogenous genes and incomplete telomere reprogramming and maintenance of porcine iPS cells. Further understanding of telomere reprogramming and maintenance may help improve the quality of porcine iPS cells.

  4. 15-THz Tunable Wavelength Conversion of Picosecond Pulses in a Silicon Waveguide

    DEFF Research Database (Denmark)

    Pu, Minhao; Hu, Hao; Galili, Michael

    2011-01-01

    We demonstrate all-optical ultra-broadband tunable wavelength conversion of 1-ps pulses based on four-wave mixing in a 3-mm-long dispersion engineered silicon waveguide. In the waveguide, an input pulse with center wavelength at 1600 nm is down-converted by 135 nm (17.3 THz) to 1465 nm. A tuning...

  5. Phase Sensitive Amplifier Based on Ultrashort Pump Pulses

    CERN Document Server

    Gershikov, Alexander

    2016-01-01

    We demonstrate a narrow band phase sensitive amplifier in the pump degenerate configuration which employs ps pump pulses. Control of the amplifier bandwidth is achieved via changes of the pump spectral width. A phase sensitive gain between -6 and 6 decibels, with an overall system gain of 28dB was demonstrated.

  6. Fragmentation dynamics of molecular hydrogen in strong ultrashort laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Rudenko, A; Feuerstein, B; Zrost, K; Jesus, V L B de; Ergler, T; Dimopoulou, C; Schroeter, C D; Moshammer, R; Ullrich, J [Max-Planck-Institut fuer Kernphysik, D-69029 Heidelberg (Germany)

    2005-03-14

    We present the results of a systematic experimental study of dissociation and Coulomb explosion of molecular hydrogen induced by intense ultrashort (7-25 fs) laser pulses. Using coincident recoil-ion momentum spectroscopy we can distinguish the contributions from dissociation and double ionization even if they result in the same kinetic energies of the fragments. The dynamics of all fragmentation channels drastically depends on the pulse duration, and for 7 fs pulses becomes extremely sensitive to the pulse shape.

  7. Precise ablation of dental hard tissues with ultra-short pulsed lasers. Preliminary exploratory investigation on adequate laser parameters.

    Science.gov (United States)

    Bello-Silva, Marina Stella; Wehner, Martin; Eduardo, Carlos de Paula; Lampert, Friedrich; Poprawe, Reinhart; Hermans, Martin; Esteves-Oliveira, Marcella

    2013-01-01

    This study aimed to evaluate the possibility of introducing ultra-short pulsed lasers (USPL) in restorative dentistry by maintaining the well-known benefits of lasers for caries removal, but also overcoming disadvantages, such as thermal damage of irradiated substrate. USPL ablation of dental hard tissues was investigated in two phases. Phase 1--different wavelengths (355, 532, 1,045, and 1,064 nm), pulse durations (picoseconds and femtoseconds) and irradiation parameters (scanning speed, output power, and pulse repetition rate) were assessed for enamel and dentin. Ablation rate was determined, and the temperature increase measured in real time. Phase 2--the most favorable laser parameters were evaluated to correlate temperature increase to ablation rate and ablation efficiency. The influence of cooling methods (air, air-water spray) on ablation process was further analyzed. All parameters tested provided precise and selective tissue ablation. For all lasers, faster scanning speeds resulted in better interaction and reduced temperature increase. The most adequate results were observed for the 1064-nm ps-laser and the 1045-nm fs-laser. Forced cooling caused moderate changes in temperature increase, but reduced ablation, being considered unnecessary during irradiation with USPL. For dentin, the correlation between temperature increase and ablation efficiency was satisfactory for both pulse durations, while for enamel, the best correlation was observed for fs-laser, independently of the power used. USPL may be suitable for cavity preparation in dentin and enamel, since effective ablation and low temperature increase were observed. If adequate laser parameters are selected, this technique seems to be promising for promoting the laser-assisted, minimally invasive approach.

  8. Dynamics of nanosecond pulsed pump ytterbium-doped double-clad fiber amplifier

    Science.gov (United States)

    Liu, Meng; Shum, Perry Ping; Xiong, Zhaoqi; Zhang, Betty Meng; Cheng, Xueping

    2017-11-01

    Pulsed pump is an effective method to suppress the amplified spontaneous emission (ASE) between pulses of high power pulsed fiber lasers. For the pulsed pump, the most important factors need to be determined during amplifier design are the pump power (PP) and pump duration (tp). In this paper, the high power ytterbium-doped double-clad fiber amplifier with pulsed pump is numerically studied. The relationship between pulse energy, efficiency and ASE with pump power and duration is investigated and experimental results are provided. The conclusions are valuable for the design of pulsed pump fiber amplifiers.

  9. Shallow PS-logging by high frequency wave; Koshuha wo mochiita senbu PS kenso

    Energy Technology Data Exchange (ETDEWEB)

    Nakajima, A.; Miyazawa, M.; Azuma, H. [OYO Corp., Tokyo (Japan)

    1996-05-01

    This paper describes the following matters on down-hole PS logging in shallow subsurface. Determining an elastic wave velocity structure in shallow subsurface with high accuracy by using down-hole PS logging requires reduction of errors in reading travel time. Therefore, a high-frequency vibration source was fabricated with an objective to raise frequencies of waves used for the measurement. Measurements were made on two holes, A and B, at a measurement interval of 0.5 m, whereas at the hole A a measurement was performed simultaneously by using a normal type (low-frequency) vibration source. A spectral analysis on the waveform record revealed that the frequencies with each vibration source were 127 Hz and 27 Hz for the hole A, 115 Hz for the hole B, and the S/N ratio was all the same for both holes. When the high-frequency vibration source was used, the velocity was determined at accuracy of 5% over the whole length of the shallow section. When the low-frequency vibration source was used, sections with the velocity determining error greater than 5% were found, and it was not possible to derive the velocity structure in the shallow subsurface in fine segments. 3 refs., 8 figs., 2 tabs.

  10. Feasibility Study of the PS Injection for 2 GeV LIU Beams with an Upgraded KFA-45 Injection Kicker System Operating in Short Circuit Mode

    CERN Document Server

    Kramer, Thomas; Borburgh, Jan; Ducimetière, Laurent; Feliciano, Luis; Ferrero Colomo, Alvaro; Goddard, Brennan; Sermeus, Luc

    2016-01-01

    Under the scope of the LIU project the CERN PS Booster to PS beam transfer will be modified to match the requirements for the future 2 GeV beams. This paper describes the evaluation of the proposed upgrade of the PS injection kicker. Different schemes of an injection for LIU beams into the PS have been outlined in the past already under the aspect of individual transfer kicker rise and fall time performances. Homogeneous rise and fall time requirements in the whole PSB to PS transfer chain have been established which allowed to consider an upgrade option of the present injection kicker system operated in short circuit mode. The challenging pulse quality constraints require an improvement of the flat top and post pulse ripples. Both operation modes, terminated and short circuit mode are analysed and analogue circuit simulations for the present and upgraded system are outlined. Recent measurements on the installed kickers are presented and analysed together with the simulation data. First measurements verifying...

  11. Short pulse, high resolution, backlighters for point projection high-energy radiography at the National Ignition Facility

    Science.gov (United States)

    Tommasini, R.; Bailey, C.; Bradley, D. K.; Bowers, M.; Chen, H.; Di Nicola, J. M.; Di Nicola, P.; Gururangan, G.; Hall, G. N.; Hardy, C. M.; Hargrove, D.; Hermann, M.; Hohenberger, M.; Holder, J. P.; Hsing, W.; Izumi, N.; Kalantar, D.; Khan, S.; Kroll, J.; Landen, O. L.; Lawson, J.; Martinez, D.; Masters, N.; Nafziger, J. R.; Nagel, S. R.; Nikroo, A.; Okui, J.; Palmer, D.; Sigurdsson, R.; Vonhof, S.; Wallace, R. J.; Zobrist, T.

    2017-05-01

    High-resolution, high-energy X-ray backlighters are very active area of research for radiography experiments at the National Ignition Facility (NIF) [Miller et al., Nucl. Fusion 44, S228 (2004)], in particular those aiming at obtaining Compton-scattering produced radiographs from the cold, dense fuel surrounding the hot spot. We report on experiments to generate and characterize point-projection-geometry backlighters using short pulses from the advanced radiographic capability (ARC) [Crane et al., J. Phys. 244, 032003 (2010); Di Nicola et al., Proc. SPIE 2015, 93450I-12], at the NIF, focused on Au micro-wires. We show the first hard X-ray radiographs, at photon energies exceeding 60 keV, of static objects obtained with 30 ps-long ARC laser pulses, and the measurements of strength of the X-ray emission, the pulse duration and the source size of the Au micro-wire backlighters. For the latter, a novel technique has been developed and successfully applied.

  12. Loudness of tone pulses in a free field

    DEFF Research Database (Denmark)

    Poulsen, Torben

    1981-01-01

    Investigations of temporal loudness summation of tone pulses have been performed. The investigations comprised equal loudness determinations between pairs of tone pulses with a duration ratio of 1:2, and threshold determinations of the same tone pulses. Pulse durations ranged from 5 to 640 ms....... The frequencies were 500, 1000, and 4000 Hz. All pulses were shaped by means of 1/3 octave filters. For 25 normal hearing observers the investigations were performed at the observer's threshold, and at 35 and 55 dB SPL. Fitting of the experimental data to a single exponential function yields a time constant (tau......) of about 200 ms near and at the threshold, whereas tau is about 100 ms at levels well above threshold. Discrepancies exist, nevertheless, between this single-time-constant model and the experimental data obtained for the pulses of shortest duration. To account for this, a model is proposed comprising...

  13. Overview of the Moral Status of iPS Cells.

    Science.gov (United States)

    Martinho, Andreia Martins

    2016-07-01

    The production of induced pluripotent stem (iPS) cells in 2006 by Takahashi and Yamanaka was a major breakthrough in stem cell research. IPS cells technology holds great promise for cell therapy, disease modelling, and drug testing, but it poses ethical questions concerning the moral status of somatic cells, which can re-gain pluripotency (iPS cells). This article provides an overview of the arguments that substantiate the debate on the moral assessment of iPS cells: potentiality argument; relational properties/standard view; and genetic basis for moral status.

  14. Duration of symptoms

    DEFF Research Database (Denmark)

    Hansen, Olfred; Larsen, Susanne; Bastholt, Lars

    2005-01-01

    PURPOSE: To study the relationship between the durations of symptoms before the start of radiotherapy and treatment outcome in Stage I-III glottic cancer. METHODS AND MATERIALS: From 1965 to 1997, 611 glottic cancer patients from the Southern Region of Denmark were treated with primary radiotherapy....... A total of 544 patients fulfilled the criteria for inclusion to the study (Stage I-III glottic cancer, a duration of symptoms less than or equal to 36 months, primary radiotherapy with at least 50 Gy and sufficient data for analysis). The total radiation dose ranged from 50.0 to 71.6 Gy in 22 to 42...

  15. 978 nm 1.24 ps ultra-short plused large mode area photonic crystal fiber laser

    Science.gov (United States)

    Li, Pingxue; Liang, Boxing; Zhang, Mengmeng; Yao, Yifei; Chi, Junjie; Hu, Haowei; Zhang, Guangju; Ma, Chunmei; Su, Ning

    2015-10-01

    We report on a 980 nm passively mode-locking Yb-doped large mode area photonic crystal fiber oscillator with semiconductor saturable absorber mirror (SESAM) and nonlinear polarization evolution (NPE) technique, simultaneously. The oscillator generates a maximum average output power of 497 mW with a repetition rate of 87.37 MHz. Because of the invisible filter effect of NPE mode-locked fiber laser, we achieved an ultra-short pulse width of 1.24 ps. The output spectrum of the pulse is centered at 977.7 nm with a full width half maximum (FWHM) of 1.90 nm and has a characteristic steep spectral edges of dissipative soliton. In this paper, the pulse evolution process of 980 nm mode-locking fiber laser is simulated and the experimental results are good agreement with the simulation results.

  16. Modified Blumlein pulse-forming networks for bioelectrical applications.

    Science.gov (United States)

    Romeo, Stefania; Sarti, Maurizio; Scarfì, Maria Rosaria; Zeni, Luigi

    2010-07-01

    Intense nanosecond pulsed electric fields (nsPEFs) have been shown to induce, on intracellular structures, interesting effects dependent on electrical exposure conditions (pulse length and amplitude, repetition frequency and number of pulses), which are known in the literature as "bioelectrical effects" (Schoenbach et al., IEEE Trans Plasma Sci 30:293-300, 2002). In particular, pulses with a shorter width than the plasma membrane charging time constant (about 100 ns for mammalian cells) can penetrate the cell and trigger effects such as permeabilization of intracellular membranes, release of Ca(2+) and apoptosis induction. Moreover, the observed effects have led to exploration of medical applications, like the treatment of melanoma tumors (Nuccitelli et al., Biochem Biophys Res Commun 343:351-360, 2006). Pulsed electric fields allowing such effects usually range from several tens to a few hundred nanoseconds in duration and from a few to several tens of megavolts per meter in amplitude (Schoenbach et al., IEEE Trans Diel Elec Insul 14:1088-1109, 2007); however, the biological effects of subnanosecond pulses have been also investigated (Schoenbach et al., IEEE Trans Plasma Sci 36:414-422, 2008). The use of such a large variety of pulse parameters suggests that highly flexible pulse-generating systems, able to deliver wide ranges of pulse durations and amplitudes, are strongly required in order to explore effects and applications related to different exposure conditions. The Blumlein pulse-forming network is an often-employed circuit topology for the generation of high-voltage electric pulses with fixed pulse duration. An innovative modification to the Blumlein circuit has been recently devised which allows generation of pulses with variable amplitude, duration and polarity. Two different modified Blumlein pulse-generating systems are presented in this article, the first based on a coaxial cable configuration, matching microscopic slides as a pulse-delivery system

  17. duration diabetes mellitus

    African Journals Online (AJOL)

    diabetes, age of onset and duration of diabetes), presence of retinopathy, markers of nephropathy ... In a recent reportlJ of an audit of primary health care servi es in Cape Town, a high prevalence of ..... Diabet Med 1995; R 546-550. 9. Hanssen ICE Determinants of microvascular complications in diabetes: an overne\\v. In:.

  18. Terrorism and cabinet duration

    NARCIS (Netherlands)

    Gassebner, M.; Jong-A-Pin, R.; Mierau, J.O.

    2011-01-01

    Terrorism can strengthen or weaken electoral support for ruling governments. We show in a simple model of coalition formation that, regardless of the direction of a public opinion shock, the impact of terrorism on cabinet duration is ambiguous. However, in an analysis of a data set including 2,400

  19. Duration of load revisited

    DEFF Research Database (Denmark)

    Hoffmeyer, Preben; Sørensen, John Dalsgaard

    2007-01-01

    A duration of load study representing 13 years of testing was recently terminated. Preliminary results have been published over the years. This paper represents the final account of the study, which was focused on the influ-ence of moisture content on time to failure for structural timber subject...

  20. Monoenergetic ion beam acceleration from transversely confined near-critical plasmas by intense laser pulses

    Science.gov (United States)

    Zhang, W. L.; Qiao, B.; Shen, X. F.; Chang, H. X.; Zhang, H.; Zhou, C. T.; He, X. T.

    2017-09-01

    An advanced target for production of high-energy monoenergetic ion beams by intense laser pulses is proposed, in which the near-critical plasma is transversely confined between the high-Z dense wires. It is found that the ion acceleration is significantly enhanced due to the strong magnetic dipole vortex formed at the rear of the target, where large electron current density gradients from the wires to the vacuum exist. The magnetic dipole vortex helps to realize the contraction of ion momentum phase spaces and reduction of the beam divergence so that monenergetic, highly directed, and collimated ion beams can be obtained. Two-dimensional particle-in-cell simulations have shown that monoenergetic proton beams with a peak energy of 105 MeV and particle number about 2.2 × 1011 are produced by using the advanced target at a laser intensity of 2.7 × 1020 W/cm2 and a pulse duration of 0.65 ps.

  1. Effect of picosecond magnetic pulse on dynamics of electron's subbands in semiconductor bilayer nanowire

    Science.gov (United States)

    Chwiej, T.

    2017-10-01

    We report on possibility of charge current generation in nanowire made of two tunnel coupled one-dimensional electron waveguides by means of single magnetic pulse lasting up to 20 ps. Existence of interlayer tunnel coupling plays a crucial role in the effect described here as it allows for hybridization of the wave functions localized in different layers which can be dynamically modified by applying a time changeable in-plane magnetic field. Results of time-dependent DFT calculations performed for a bilayer nanowire confining many electrons show that the effect of such magnetic hybridization relies on tilting of electrons' energy subbands, to the left or to the right, depending on a sign of time derivative of oscillating magnetic field due to the Faraday law. Consequently, the tilted subbands become a source of charge flow along the wire. Strength of such magneto-induced current oscillations may achieve even 0.6 μA but it depends on duration of magnetic pulse as well as on charge density confined in nanowire which has to be unequally distributed between both transport layers to observe this effect.

  2. Repetitive pulses and laser-induced retinal injury thresholds

    Science.gov (United States)

    Lund, David J.

    2007-02-01

    Experimental studies with repetitively pulsed lasers show that the ED 50, expressed as energy per pulse, varies as the inverse fourth power of the number of pulses in the exposure, relatively independently of the wavelength, pulse duration, or pulse repetition frequency of the laser. Models based on a thermal damage mechanism cannot readily explain this result. Menendez et al. proposed a probability-summation model for predicting the threshold for a train of pulses based on the probit statistics for a single pulse. The model assumed that each pulse is an independent trial, unaffected by any other pulse in the train of pulses and assumes that the probability of damage for a single pulse is adequately described by the logistic curve. The requirement that the effect of each pulse in the pulse train be unaffected by the effects of other pulses in the train is a showstopper when the end effect is viewed as a thermal effect with each pulse in the train contributing to the end temperature of the target tissue. There is evidence that the induction of cell death by microcavitation bubbles around melanin granules heated by incident laser irradiation can satisfy the condition of pulse independence as required by the probability summation model. This paper will summarize the experimental data and discuss the relevance of the probability summation model given microcavitation as a damage mechanism.

  3. PS buildings : reinforced concrete structure for shielding "bridge" pillar

    CERN Multimedia

    CERN PhotoLab

    1956-01-01

    The PS ring traverses the region between the experimental halls South and North (buildings Nos 150 and 151) under massive bridge-shaped concrete beams. This pillar stands at the S-W end of the structure.

  4. New safety training for access to the PS complex areas

    CERN Multimedia

    2012-01-01

    Since 10/08/2012, a new course dedicated to the specific radiological risks in the accelerators of the PS complex has been available on SIR (https://sir.cern.ch/). This course complements the general classroom-based Radiation Safety training. Successful completion of the course will be obligatory and verified by the access system as from 01/11/2012 for access to the following accelerator areas: LINAC2, BOOSTER, PS and TT2. Information and reminder e-mails will be sent to all persons currently authorized to access the accelerators of the PS complex. For questions please contact the HSE unit and in particular, the Radiation Protection Group (+41227672504 or safety-rp-ps-complex@cern.ch).

  5. Experimental validation of a high voltage pulse measurement method.

    Energy Technology Data Exchange (ETDEWEB)

    Cular, Stefan; Patel, Nishant Bhupendra; Branch, Darren W.

    2013-09-01

    This report describes X-cut lithium niobates (LiNbO3) utilization for voltage sensing by monitoring the acoustic wave propagation changes through LiNbO3 resulting from applied voltage. Direct current (DC), alternating current (AC) and pulsed voltage signals were applied to the crystal. Voltage induced shift in acoustic wave propagation time scaled quadratically for DC and AC voltages and linearly for pulsed voltages. The measured values ranged from 10 - 273 ps and 189 ps 2 ns for DC and non-DC voltages, respectively. Data suggests LiNbO3 has a frequency sensitive response to voltage. If voltage source error is eliminated through physical modeling from the uncertainty budget, the sensors U95 estimated combined uncertainty could decrease to ~0.025% for DC, AC, and pulsed voltage measurements.

  6. Study of Value Co-Creation in CoPS

    OpenAIRE

    Mingli Zhang; Jianhua Ye

    2013-01-01

    Value co-creation is associated with specific investment in the context of CoPS. The feature of CoPS decides that the study of co-creation cannot execute without regarding asset specificity. This study considers that value co-creation will be associated with specific value, which is outcome of relationship value and asset specificity. Supplier and customer have a close relation, which conducts to specific investment and then it turns to obstacle for competitors. Trust, commitment and satisfac...

  7. The Libera as a PS orbit measurement system building block

    CERN Document Server

    Belleman, J M; CERN. Geneva. AB Department

    2005-01-01

    During the year 2004, extensive tests using a Libera data processor have been made in order to study its suitability as a building block for a complete PS trajectory and orbit measurement system. The Libera consists of four fast 12-bits ADCs, a Virtex II Pro FPGA and a large memory. This note presents some of the results of the analysis of acquisitions made on a position pick-up in the CERN PS.

  8. DiPS: A Unifying Approach for developing System Software

    OpenAIRE

    Michiels, Sam; Matthijs, Frank; Walravens, Dirk; Verbaeten, Pierre

    2002-01-01

    In this paper we unify three essential features for flexible system software: a component oriented approach, self-adaptation and separation of concerns.We propose DiPS (Distrinet Protocol Stack), a component framework, which offers components, an anonymous interaction model and connectors to handle non-functional aspects such as concurrency. DiPS has effectively been used in industrial protocol stacks and device drivers.

  9. Laser-induced back-ablation of aluminum thin films using picosecond laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    BULLOCK, A B

    1999-05-26

    Experiments were performed to understand laser-induced back-ablation of Al film targets with picosecond laser pulses. Al films deposited on the back surface of BK-7 substrates are ablated by picosecond laser pulses propagating into the Al film through the substrate. The ablated Al plume is transversely probed by a time-delayed, two-color sub-picoseond (500 fs) pulse, and this probe is then used to produce self-referencing interferograms and shadowgraphs of the Al plume in flight. Optical emission from the Al target due to LIBA is directed into a time-integrated grating spectrometer, and a time-integrating CCD camera records images of the Al plume emission. Ablated Al plumes are also redeposited on to receiving substrates. A post-experimental study of the Al target and recollected deposit characteristics was also done using optical microscopy, interferometry, and profilometry. In this high laser intensity regime, laser-induced substrate ionization and damage strongly limits transmitted laser fluence through the substrate above a threshold fluence. The threshold fluence for this ionization-based transmission limit in the substrate is dependent on the duration of the incident pulse. The substrate ionization can be used as a dynamic control of both transmitted spatial pulse profile and ablated Al plume shape. The efficiency of laser energy transfer between the laser pulse incident on the Al film and the ablated Al plume is estimated to be of order 5% and is a weak function of laser pulsewidth. The Al plume is highly directed. Low plume divergence ({theta}{sub divergence} < 5{sup o}) shows the ablated plume temperature to be very low at long time delays ( T << 0.5 eV at delays of 255 ns). Spectroscopic observations and calculations indicate that, in early time (t < 100 ps), the Al film region near the substrate/metal interface is at temperatures of order 0.5 eV. Interferograms of Al plumes produced with 0.1 {micro}m films show these plumes to be of high neutral atom

  10. An innovative high-power constant-current pulsed-arc power-supply for a high-density pulsed-arc-plasma ion-source using a LaB6-filament.

    Science.gov (United States)

    Ueno, A; Oguri, H; Ikegami, K; Namekawa, Y; Ohkoshi, K; Tokuchi, A

    2010-02-01

    An innovative high-power constant-current (CC) pulsed-arc (PA) power-supply (PS) indispensable for a high-density PA plasma ion-source using a lanthanum hexaboride (LaB(6)) filament was devised by combining a constant-voltage (CV) PA-PS, which is composed of an insulated gate bipolar transistor (IGBT) switch, a CV direct-current (dc) PS and a 270 mF capacitor with a CC-PA-PS, which is composed of an IGBT-switch, a CC-dc-PS and a 400 microH inductor, through the inductor. The hybrid-CC-PA-PS succeeded in producing a flat arc-pulse with a peak power of 56 kW (400 A x 140 V) and a duty factor of more than 1.5% (600 micros x 25 Hz) for Japan Proton Accelerator Research Complex (J-PARC) H(-) ion-source stably. It also succeeded in shortening the 99% rising-time of the arc-pulse-current to about 20 micros and tilting up or down the arc-pulse-current arbitrarily and almost linearly by changing the setting voltage of its CV-dc-PS.

  11. iPS-Cinderella Story in Cell Biology

    Directory of Open Access Journals (Sweden)

    Editorial

    2010-01-01

    Full Text Available As we step through the frontiers of modern Science, we are all witnesses to the Cinderella story repeating itself in the form of the iPS. The process of re-programming adult somatic cells to derive Induced Pluripotent stem cells (iPS with the wand of transcription factors and then differentiating them back to adult somatic cells resembles the transformation of Cinderella from a Cinder girl to princess and back to a Cinder girl after the ball; but the iPS-Cinderella is the most fascinating thing ever in cell biology!From the day iPS first made its headlines when it was first produced by Shinya Yamanaka at Kyoto University in Japan, Stem Cell scientists all over the world are re- doing their experiments so far done using other sources like embryonic and adult Stem cells with the iPS cells exploring their potential to the fullest. A Stem Cell science news page without this magic word of iPS is difficult to imagine these days and Scientists have been successful in growing most of the adult Cell types from iPS cells.iPS cells was the key to solve the problems of Immune rejection and Immunosupression required when using other allogeneic Stem cell types which had baffled scientists previously. But the issues raised by scientists about the use of viruses and Oncogenes in producing iPS cells were made groundless when scientists in February 2008 published the discovery of a technique that could remove oncogenes after the induction of pluripotency and now it is possible to induce pluripotency using plasmid transfection, piggyback transposon system and piggyback transposon system combined with a non viral vector system. The word of the day is pIPS which are protein-induced Pluripotent stem cells which are iPS cells that were generated without any genetic alteration of the adult cell. This research by the group of Sheng Ding in La Jolla, California made public in April 2009 showed that the generation of poly-arginine anchors was sufficient to induce

  12. Simulation of a wide area survey for NEOs with Pan-STARRS PS1 & PS2 Telescopes

    Science.gov (United States)

    Chambers, Kenneth C.; Lilly (Schunova), Eva; Dukes, Martin Todd; Wainscoat, Richard J.

    2017-10-01

    We have performed a new survey simulation for a wide area survey with PS1 & PS2 as part of our quest to optimize the discovery rate of Near Earth Objects with the full Pan-STARRS system. The survey is intended to be as unbiased and as complete as possible given the available sky visibility and the anticipated performance of the PS1 and PS2 telescopes working together. The simulation includes a complete model of both telescopes, camera and slew overhead, sky visibility, moon phase, galactic plane exclusion, and weather. The performance of the resulting survey strategy is then evaluated using the method of Lilly et. al. 2017. This uses the Greenstreet et al. 2012 model with 50 million NEOs with absolute magnitudes 13 < H < 29 and the Moving Object Processing System (MOPS, Denneau et al. 2013) for linkages. The results are compared with other possible strategies.

  13. Time-gated single-photon detection module with 110 ps transition time and up to 80 MHz repetition rate

    Energy Technology Data Exchange (ETDEWEB)

    Buttafava, Mauro, E-mail: mauro.buttafava@polimi.it; Boso, Gianluca; Ruggeri, Alessandro; Tosi, Alberto [Politecnico di Milano, Dipartimento di Elettronica, Informazione e Bioingegneria, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy); Dalla Mora, Alberto [Politecnico di Milano, Dipartimento di Fisica, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy)

    2014-08-15

    We present the design and characterization of a complete single-photon counting module capable of time-gating a silicon single-photon avalanche diode with ON and OFF transition times down to 110 ps, at repetition rates up to 80 MHz. Thanks to this sharp temporal filtering of incoming photons, it is possible to reject undesired strong light pulses preceding (or following) the signal of interest, allowing to increase the dynamic range of optical acquisitions up to 7 decades. A complete experimental characterization of the module highlights its very flat temporal response, with a time resolution of the order of 30 ps. The instrument is fully user-configurable via a PC interface and can be easily integrated in any optical setup, thanks to its small and compact form factor.

  14. Duration Calculus: Logical Foundations

    DEFF Research Database (Denmark)

    Hansen, Michael Reichhardt; Chaochen, Zhou

    1997-01-01

    The Duration Calculus (abbreviated DC) represents a logical approach to formal design of real-time systems, where real numbers are used to model time and Boolean valued functions over time are used to model states and events of real-time systems. Since it introduction, DC has been applied to many...... case studies and it has been extended in several directions. The aim of this paper is to provide a thorough presentation of the logic.......The Duration Calculus (abbreviated DC) represents a logical approach to formal design of real-time systems, where real numbers are used to model time and Boolean valued functions over time are used to model states and events of real-time systems. Since it introduction, DC has been applied to many...

  15. Digital Pulse-Width-Modulation Circuit

    Science.gov (United States)

    Wenzler, Carl J.; Eichenberg, Dennis J.

    1995-01-01

    Digital pulse-width-modulation circuit provides programmable duration from 1 microsecond to full on, at repetition rate of 1 kHz. Designed for use in controlling CO2 laser, also used in applications in which precision and flexibility of digital control of pulse durations needed. Circuit incorporates low-power Schottky transistor/transistor-logic (TTL) devices in critical high-speed parts. Designed in TTL to make it compatible with Pro-Log 7914 (or equivalent) decoder input/output (I/O) utility printed-circuit card.

  16. Profiling the microRNA Expression in Human iPS and iPS-derived Retinal Pigment Epithelium.

    Science.gov (United States)

    Wang, Heuy-Ching; Greene, Whitney A; Kaini, Ramesh R; Shen-Gunther, Jane; Chen, Hung-I H; Cai, Hong; Wang, Yufeng

    2014-01-01

    The purpose of this study is to characterize the microRNA (miRNA) expression profiles of induced pluripotent stem (iPS) cells and retinal pigment epithelium (RPE) derived from induced pluripotent stem cells (iPS-RPE). MiRNAs have been demonstrated to play critical roles in both maintaining pluripotency and facilitating differentiation. Gene expression networks accountable for maintenance and induction of pluripotency are linked and share components with those networks implicated in oncogenesis. Therefore, we hypothesize that miRNA expression profiling will distinguish iPS cells from their iPS-RPE progeny. To identify and analyze differentially expressed miRNAs, RPE was derived from iPS using a spontaneous differentiation method. MiRNA microarray analysis identified 155 probes that were statistically differentially expressed between iPS and iPS-RPE cells. Up-regulated miRNAs including miR-181c and miR-129-5p may play a role in promoting differentiation, while down-regulated miRNAs such as miR-367, miR-18b, and miR-20b are implicated in cell proliferation. Subsequent miRNA-target and network analysis revealed that these miRNAs are involved in cellular development, cell cycle progression, cell death, and survival. A systematic interrogation of temporal and spatial expression of iPS-RPE miRNAs and their associated target mRNAs will provide new insights into the molecular mechanisms of carcinogenesis, eye differentiation and development.

  17. Note: fast double pulse system using transmission line characteristic of the pulse forming line.

    Science.gov (United States)

    Sharma, Surender Kumar; Deb, P; Sharma, Archana; Shyam, A

    2012-11-01

    A fast double pulse system is designed and developed using the transmission line characteristic of the pulse forming line to generate two flat top rectangular pulses with extremely short interpulse repetition interval. The helical pulse forming line (HPFL) is used to generate longer duration rectangular pulses in smaller length. The HPFL inner conductor is made up of 13 turns of SS-304 strip, 39.5 mm wide and 0.5 mm thick wounded on the 168 mm delrin cylinder. The impedance of the HPFL is 22 Ω. The 2 turns at the input side of the HPFL are wounded with ethylene propylene rubber tape on the strip. The HPFL is charged to 180 kV in 4 μs and discharges into a matched load through a spark switch. It generates two flat top rectangular pulses of 90 kV, 100 ns duration with the 30 ns interval between the pulses. The system can be used as fast double pulse source for repetitive pulsed power loads.

  18. Alignment enhancement of a symmetric top molecule by two short laser pulses

    DEFF Research Database (Denmark)

    Bisgaard, Christer Z; Viftrup, Simon; Stapelfeldt, Henrik

    2006-01-01

    equation. It is shown that the strongest degree of one-dimensional (single axis) field-free alignment obtainable with a single pulse can be enhanced using the two-pulse sequence in a parallel polarization geometry. The conditions for alignment enhancement are: (1) The second pulse must be sent near...... the time where the degree of alignment, due to the first pulse, peaks. (2) The intensity of the first pulse must be smaller than the intensity of the second pulse, the optimal intensity ratio being determined by the duration of the pulses. Numerically, we also discuss the existence of an optimal pulse...

  19. Four-wave mixing with femtosecond pulses

    Energy Technology Data Exchange (ETDEWEB)

    Skenderovic, H [Institute of Physics, Bijenicka cesta 46, HR-10001 Zagreb (Croatia)], E-mail: hrvoje@ifs.hr

    2009-07-15

    The recent development of noncollinear optical parametric amplifiers (NOPAs) has equipped many laboratories with widely tunable, spectrally broad ultrashort laser pulses with a duration of 15-30 fs. The present work deals with sub-20 fs pulsed degenerate four wave mixing (DFWM) on high-frequency vibrational levels in all-trans-{beta}-carotene. The observed wavepacket motion on the electronic ground state revealed fast oscillating vibrational modes whose frequencies and time development were measured. The coherent control in an open loop is demonstrated by appropriate phase shaping of the pulses.

  20. The Merit(nTOF-11) High Intensity Liquid Mercury Target Experiment at the CERN PS

    CERN Document Server

    Efthymiopoulos, I; Caretta, O; Carroll, A J; Fabich, A; Graves, V B; Grudiev, A; Haug, F; Kirk, H G; Lettry, Jacques; Loveridge, P; McDonald, K T; Mokhov, N; Palm, M; Park, H; Pernegger, H; Spampinato, P T; Steerenberg, R; Striganov, S; Tsang, T

    2008-01-01

    The MERIT(nTOF-11) experiment is a proof-ofprinciple test of a target system for a high power proton beam to be used as front-end for a neutrino factory or a muon collider. The experiment took data in autumn 2007 with the fast-extracted beam from the CERN Proton Synchrotron (PS) to a maximum intensity of $30 × 10^{12}$ per pulse. The target system, based on a free mercury jet, is capable of intercepting a 4-MW proton beam inside a 15-T magnetic field required to capture the low energy secondary pions as the source for intense muon beams. Partice detectors installed around the target setup measure the secondary particle flux out of the target and can probe cavitation effects in the mercury jet when excited by an intense proton beam.Preliminary results of the data analysis will be presented here.

  1. Laser breakdown in air at ultrahigh laser pulse repetition rates

    Energy Technology Data Exchange (ETDEWEB)

    Kononenko, Vitalii V; Kononenko, Taras V; Pashinin, V P; Gololobov, V M; Konov, Vitalii I [A M Prokhorov General Physics Institute, Russian Academy of Sciences, Moscow (Russian Federation)

    2013-04-30

    Some specific features of interaction of intense femtosecond laser pulses with air at ultrahigh pulse repetition rates have been experimentally studied. Data on the dynamics of plasma cloud expansion and the plasma electron density on time intervals no longer than 10 ns are obtained by femtosecond interferometry. These data are interpreted in terms of the most likely mechanisms of ionised gas recombination. The effect of ultrahigh-frequency laser radiation on a medium was modelled by double-pulse irradiation with a short delay {Delta}t between the pulses: from 1 ps to 11 ns. A nonmonotonic dependence of the degree of air ionisation by the second pulse on the delay time {Delta}t is found; possible mechanisms of these dependences are discussed in terms of the processes of femtosecond radiation absorption in the residual plasma. (extreme light fields and their applications)

  2. Multifunctional optical correlator for picosecond ultraviolet laser pulse measurement.

    Science.gov (United States)

    Rakhman, Abdurahim; Wang, Yang; Garcia, Frances; Long, Cary; Huang, Chunning; Takeda, Yasuhiro; Liu, Yun

    2014-11-01

    A compact multifunctional optical correlator system for pulse width measurement of ultrashort ultraviolet (UV) pulses has been designed and experimentally demonstrated. Both autocorrelation and cross-correlation functions are measured using a single nonlinear crystal, and the switching between two measurements requires no adjustment of phase matching and detector. The system can measure UV pulse widths from sub-picoseconds to 100 ps, and it involves no auxiliary pulse in the measurement. The measurement results on a burst-mode picosecond UV laser show a high-quality performance on speed, accuracy, resolution, and dynamic range. The proposed correlator can be applied to measure any ultrashort UV pulses produced through sum-frequency generation or second-harmonic generation.

  3. Characterization of crosslinked polystyrene(PS) beads in SBR matrix

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Yoon-Jong; Choe, Soonja [Inha Univ. (Korea, Republic of)

    1995-12-01

    Monodisperse sized crosslinked polystyrene(PS) beads were prepared by a reaction of semibatch emulsion polymerization with styrene monomer, divinylbenzene(DVB) crosslinking agent and potassium persulfate(K{sub 2}S{sub 2}O{sub 9}) initiator in the absence of emulsifier. The glass transition temperature(T{sub g}) and the mean diameter of the beads were increased from 100{degrees}C to 135{degrees}C and from 402 nm to 532 nm, respectively, for an incorporation of 2 to 10 mol% DVB. Crosslinking density was also linearly increased with DVB content. SEM microphotographs of SBR composite filled with various contents of PS beads revealed that PS beads are relatively well dispersed without changing the spherical shape of the beads in all range of compositions. In stress-strain analysis, elongation at break and tensile strength of SBR composite were increased with the bead content. Applicability of the PS beads as a filler in SBR matrix is tested by plotting Mooney-Rivlin or Guth-Smallwood equations. However, mechanical properties of the composite with the beads were not so excellent as those of the composite with carbon black. Crosslinked PS beads are still tentative as a white color reinforcing filler on SBR matrix.

  4. The PS complex produces the nominal LHC beam

    CERN Document Server

    Benedikt, Michael; Borburgh, J; Cappi, R; Chanel, M; Chohan, V; Cyvoct, G; Garoby, R; Grier, D G; Gruber, J; Hancock, S; Hill, C E; Jensen, E; Krusche, A; Lindroos, M; Métral, Elias; Métral, G; Metzmacher, K D; Olsfors, J; Pedersen, F; Raich, U; Riunaud, J P; Royer, J P; Sassowsky, M; Schindl, Karlheinz; Schönauer, Horst Otto; Thivent, M; Ullrich, H M; Völker, F V; Vretenar, Maurizio; Barnes, M; Blackmore, E W; Cifarelli, F; Clark, G; Jones, F; Koscielniak, Shane Rupert; Mammarella, F; Mitra, A; Poirier, R; Reiniger, K W; Ries, T C

    2000-01-01

    The LHC [1] will be supplied, via the SPS, with protons from the pre-injector chain comprising Linac2, PS Booster (PSB) and PS. These accelerators have under-gone a major upgrading programme [2] during the last five years so as to meet the stringent requirements of the LHC. These imply that many high-intensity bunches of small emittance and tight spacing (25 ns) be available at the PS extraction energy (25 GeV). The upgrading project involved an increase of Linac2 current, new RF systems in the PSB and the PS, raising the PSB energy from 1 to 1.4 GeV, two-batch filling of the PS and the installation of high-resolution beam profile measurement devices. With the project entering its final phase and most of the newly installed hardware now being operational, the emphasis switches to producing the nominal LHC beam and tackling the associated beam physics problems. While a beam with transverse characteristics better than nominal has been obtained, the longitudinal density still needs to be increased. An alternativ...

  5. Fiber optic picosecond laser pulse transmission line for hydrogen ion beam longitudinal profile measurement.

    Science.gov (United States)

    Huang, Chunning; Liu, Yun; Aleksandrov, Alexander

    2013-07-01

    We present a fiber optic laser pulse transmission line for nonintrusive longitudinal profile measurement of the hydrogen ion (H(-)) beam at the front-end of the Spallation Neutron Source accelerator. The 80.5 MHz, 2.5 ps, multikilowatt optical pulses are delivered to the accelerator beam line through a large-mode-area polarization-maintaining optical fiber to ensure high measurement stability. The transmission efficiency, output laser beam quality, pulse jitter, and pulse width broadening over a 30 m long fiber line are experimentally investigated. A successful measurement of the H(-) beam microbunch (~130 ps) profile is obtained. The experiment is the first demonstration to our knowledge of particle beam profile diagnostics using a fiber optic laser pulse transmission line.

  6. High-speed pulse train amplification in semiconductor optical amplifiers with optimized bias current.

    Science.gov (United States)

    Xia, Mingjun; Ghafouri-Shiraz, H; Hou, Lianping; Kelly, Anthony E

    2017-02-01

    In this paper, we have experimentally investigated the optimized bias current of semiconductor optical amplifiers (SOAs) to achieve high-speed input pulse train amplification with high gain and low distortion. Variations of the amplified output pulse duration with the amplifier bias currents have been analyzed and, compared to the input pulse duration, the amplified output pulse duration is broadened. As the SOA bias current decreases from the high level (larger than the saturated bias current) to the low level, the broadened pulse duration of the amplified output pulse initially decreases slowly and then rapidly. Based on the analysis, an optimized bias current of SOA for high-speed pulse train amplification is introduced. The relation between the SOA optimized bias current and the parameters of the input pulse train (pulse duration, power, and repetition rate) are experimentally studied. It is found that the larger the input pulse duration, the lower the input pulse power or a higher repetition rate can lead to a larger SOA optimized bias current, which corresponds to a larger optimized SOA gain. The effects of assist light injection and different amplifier temperatures on the SOA optimized bias current are studied and it is found that assist light injection can effectively increase the SOA optimized bias current while SOA has a lower optimized bias current at the temperature 20°C than that at other temperatures.

  7. Final Results on the CERN PS Electrostatic Septa Consolidation Program

    CERN Document Server

    Borburgh, Jan; Bobbio, Piero; Carlier, Etienne; Hourican, Michael; Masson, Thierry; Müller, Tania; Prost, Antoine; Crescenti, Massimo

    2003-01-01

    The CERN PS electrostatic septum consolidation program is coming to completion after almost 4 years of development. The program was started to fulfil the increased requirements on vacuum performance and the need to reduce the time necessary for maintenance interventions. The new design of septum 31, used for the so-called 'continuous transfer' 5-turn extraction, and the related construction issues will be presented together with the operational experience gained during the PS 2002 run. In addition, the experience of two years of operation with the new generation septum 23, used for a resonant slow extraction, will be briefly discussed. The continued development undertaken since its installation in the PS ring in 2001 will also be described.

  8. A&T Sector Note on the PS transverse feedback

    CERN Document Server

    Coly, Marcel; Blas, Alfred; Sterbini, Guido; CERN. Geneva. ATS Department

    2017-01-01

    In a particle accelerator, several contributions can degrade the beam quality and particularly the beam transverse emittance. In this document we will describe a system used in the CERN Proton Synchrotron (PS) to cope with the injection steering errors and the transverse instabilities: the PS transverse feedback (PS TFB). As time progresses, this system is also being used for other purpose, to increase in a controlled way the beam transverse emittance and to excite the beam for the Multi-Turn-Extraction (MTE). In 2016, it has been successfully used on some operational beams to damp injection oscillations. This allowed to test the reliability of the system for its operational deployment. A piquet service is available in case of problem.

  9. SAFETY: STRICTER CONTROLS IN CONTROLLED AREAS IN THE PS

    CERN Document Server

    G. Daems

    2001-01-01

    The PS accelerators will soon stop for several months. Work will take place in controlled areas in the PS and will involve many people who are not always aware of the risks associated with the work sites. To guarentee the safety of these workers, the following two measures will be applied: everyone working in a controlled zone - Linacs, PSB, and PS machines tunnels, and transfer lines - must wear, visibly, his CERN access card and his film badge. the CERN access card and the film badge will only be issued after following a basic safety course. Regular checks will be carried out during the shutdown. Anyone without these two items on their person will be obliged to leave the area immediately.

  10. Electrophysical properties of PMN-PT-PS-PFN:Li ceramics

    Directory of Open Access Journals (Sweden)

    R. Skulski

    2013-01-01

    Full Text Available We present the technology of obtaining and the electrophysical properties of a multicomponent material 0.61PMN-0.20PT-0.09PS-0.1PFN:Li (PMN-PT-PS-PFN:Li. The addition of PFN into PMN-PT decreases the temperature of final sintering which is very important during technological process (addition of Li decreases electric conductivity of PFN. Addition of PS i.e., PbSnO3 (which is unstable in ceramic form permits to shift the temperature of the maximum of dielectric permittivity. One-step method of obtaining ceramic samples from oxides and carbonates has been used. XRD, microstructure, scanning calorimetry measurements and the main dielectric, ferroelectric and electromechanical properties have been investigated for the obtained samples.

  11. Femtosecond-Laser-Pulse Characterization and Optimization for CARS Microscopy.

    Directory of Open Access Journals (Sweden)

    Vincenzo Piazza

    Full Text Available We present a simple method and its experimental implementation to determine the pulse durations and linear chirps of the pump-and-probe pulse and the Stokes pulse in a coherent anti-Stokes Raman scattering microscope at sample level without additional autocorrelators. Our approach exploits the delay line, ubiquitous in such microscopes, to perform a convolution of the pump-and-probe and Stokes pulses as a function of their relative delay and it is based on the detection of the photons emitted from an appropriate non-linear sample. The analysis of the non-resonant four-wave-mixing and sum-frequency-generation signals allows for the direct retrieval of the pulse duration on the sample and the linear chirp of each pulse. This knowledge is crucial in maximizing the spectral-resolution and contrast in CARS imaging.

  12. Effect of interfaces on the melting of PEO confined in triblock PS-b-PEO-b-PS copolymers.

    Science.gov (United States)

    Beaudoin, E; Phan, T N T; Robinet, M; Denoyel, R; Davidson, P; Bertin, D; Bouchet, R

    2013-08-27

    Block copolymers form nanostructures that have interesting physical properties because they combine, for a single compound, the complementary features brought by each block. However, in order to fully exploit these properties, the physical state of each kind of domain must be precisely controlled. In this work, triblock PS-b-PEO-b-PS copolymers consisting of a central poly(ethylene oxide) (PEO) block covalently bonded to polystyrene (PS) blocks were synthesized by Atom Transfer Radical Polymerization. Their morphology was investigated by X-ray scattering and TEM experiments whereas their thermodynamic behavior was characterized by DSC. A strong decrease of both the melting temperature and the degree of crystallinity of PEO, due to its confinement between the PS domains, was observed and analyzed with a modified Gibbs-Thomson equation, following the approaches used for fluids confined in porous media. The existence of an amorphous bound layer, a few nanometers thick, at the PEO/PS interface, that does not undergo any phase transition in the temperature range investigated, accounts for both the melting temperature depression and the decrease of crystallinity upon confinement. This interfacial layer may significantly affect the mechanical and transport properties of these block copolymers that find applications as solid polymer electrolytes in batteries for example. Moreover, the value obtained for the solid PEO/liquid PEO surface tension is lower than those previously published but is thermodynamically consistent with the surface tensions of polymers at the solid/vapor and liquid/vapor interfaces.

  13. The Duration of Motor Responses Evoked with Intracortical Microstimulation in Rats Is Primarily Modulated by Stimulus Amplitude and Train Duration.

    Directory of Open Access Journals (Sweden)

    Meghan Watson

    Full Text Available Microstimulation of brain tissue plays a key role in a variety of sensory prosthetics, clinical therapies and research applications, however the effects of stimulation parameters on the responses they evoke remain widely unknown. In particular, the effects of parameters when delivered in the form of a stimulus train as opposed to a single pulse are not well understood despite the prevalence of stimulus train use. We aimed to investigate the contribution of each parameter of a stimulus train to the duration of the motor responses they evoke in forelimb muscles. We used constant-current, biphasic, square wave pulse trains in acute terminal experiments under ketamine anaesthesia. Stimulation parameters were systematically tested in a pair-wise fashion in the caudal forelimb region of the motor cortex in 7 Sprague-Dawley rats while motor evoked potential (MEP recordings from the forelimb were used to quantify the influence of each parameter in the train. Stimulus amplitude and train duration were shown to be the dominant parameters responsible for increasing the total duration of the MEP, while interphase interval had no effect. Increasing stimulus frequency from 100-200 Hz or pulse duration from 0.18-0.34 ms were also effective methods of extending response durations. Response duration was strongly correlated with peak time and amplitude. Our findings suggest that motor cortex intracortical microstimulations are often conducted at a higher frequency rate and longer train duration than necessary to evoke maximal response duration. We demonstrated that the temporal properties of the evoked response can be both predicted by certain response metrics and modulated via alterations to the stimulation signal parameters.

  14. [Intrastromal refractive corneal surgery with pico-second Nd:YAG laser pulses].

    Science.gov (United States)

    Vogel, A; Asiyo-Vogel, M; Birngruber, R

    1994-10-01

    Intrastromal laser surgery with picosecond pulses aims to achieve refractive changes of the cornea without damaging the epithelium, Bowman's membrane, or the endothelium. For that, a tissue layer with well-defined thickness has to be evaporated by creating laser plasmas within the corneal stroma. We investigated the plasma formation and the plasma-induced shock wave emission and bubble generation (cavitation) in the cornea, as well as the tissue effects and the range for endothelial damage. The laser light source used was an Nd:YAG laser emitting pulses with a duration of 30 ps at a repetition rate of 10 Hz. Intrastromal plasma formation and cavitation were investigated in sheep eyes in vitro by means of time-resolved macro-photography with 20 ns exposure time. Photographs were taken at various delay times (3 microseconds-2 min) after the release of the Nd:YAG laser pulse. The morphology of the laser effects and the incidence of endothelial damage was investigated by light-microscopic inspection of histological cross sections of the irradiated corneas. The minimal plasma size at energies close to the breakdown threshold was about 40 microns. Using a laser effects could be created without causing microscopically detectable damage to the epithelium, endothelium, or Bowman's membrane. To avoid damage, the distance between endothelium and laser focus had to be larger than 150 microns. Shock wave-induced tissue damage was not observed, although the maximum shock wave pressure was up to 13 kbar. The laser-generated intrastromal cavities are at least 10 times larger than the plasma volume.(ABSTRACT TRUNCATED AT 250 WORDS)

  15. Ablation of porcine bone tissue with an ultrashort pulsed laser (USPL) system.

    Science.gov (United States)

    Plötz, Christina; Schelle, Florian; Bourauel, Christoph; Frentzen, Matthias; Meister, Jörg

    2015-04-01

    Ultrashort pulsed lasers (USPLs) represent a new generation of laser systems in the field of biophotonical applications. In terms of a pilot project, the study was carried out to evaluate the ablation parameters of bone tissue regarding the medical use of such a laser technology in dentistry. Specimens from ribs of freshly slaughtered pigs were assembled and irradiated with an USP Nd:YVO4 laser (pulse duration 8 ps at 1,064 nm with repetition rates between 50 and 500 kHz) using eligible average output powers in the range of 3.5-9 W and fluences between 1 and 2.5 J/cm(2). Square-shaped cavities of 1-mm edge length in the bone compacta were created employing a scanner system. Cavities were analyzed with an optical profilometer to determine the ablated volume. Ablation rate was calculated by the ablated volume and the recorded irradiation time by the scanner software. Additionally, samples were examined histologically to investigate side effects of the surrounding tissue. Formed cavities showed a precise and sharp-edged appearance in bone compacta. Optimized ablation rate of 5.2 mm(3)/min without any accompanying side effects was obtained with an average output power of 9 W, a pulse repetition rate of 500 kHz, and an applied fluence of 2.5 J/cm(2). Provided that the used laser system will be advanced and adjusted for clinical applications, the outcome of this study shows auspicious possibilities for the use of USPL systems in the preparation of bone tissue.

  16. Long duration flights management

    Science.gov (United States)

    Sosa-Sesma, Sergio; Letrenne, Gérard; Spel, Martin; Charbonnier, Jean-Marc

    Long duration flights (LDF) require a special management to take the best decisions in terms of ballast consumption and instant of separation. As a contrast to short duration flights, where meteorological conditions are relatively well known, for LDF we need to include the meteorological model accuracy in trajectory simulations. Dispersions on the fields of model (wind, temperature and IR fluxes) could make the mission incompatible with safety rules, authorized zones and others flight requirements. Last CNES developments for LDF act on three main axes: 1. Although ECMWF-NCEP forecast allows generating simulations from a 4D point (altitude, latitude, longitude and UT time), result is not statistical, it is determinist. To take into account model dispersion a meteorological NCEP data base was analyzed. A comparison between Analysis (AN) and Forecast (FC) for the same time frame had been done. Result obtained from this work allows implementing wind and temperature dispersions on balloon flight simulator. 2. For IR fluxes, NCEP does not provide ascending IR fluxes in AN mode but only in FC mode. To obtain the IR fluxes for each time frame, satellite images are used. A comparison between FC and satellites measurements had been done. Results obtained from this work allow implementing flux dispersions on balloon flight simulator. 3. An improved cartography containing a vast data base had been included in balloon flight simulator. Mixing these three points with balloon flight dynamics we have obtained two new tools for observing balloon evolution and risk, one of them is called ASTERISK (Statistic Tool for Evaluation of Risk) for calculations and the other one is called OBERISK (Observing Balloon Evolution and Risk) for visualization. Depending on the balloon type (super pressure, zero pressure or MIR) relevant information for the flight manager is different. The goal is to take the best decision according to the global situation to obtain the largest flight duration with

  17. Inauguration of POPS: the new power system of the PS

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    Pictures 03 and 04 : The team from the Electrical Power Converters Group (TE/EPC) is joined by the Director of Accelerators, the heads of the BE, TE and FI departments, CERN managers and Converteam representatives in a group portrait in front of three of the containers that house the capacitor banks of the PS's new power supply system, POPS. Pictures 01, 06 and 07 : Magid-Michel Saikaly, energy and infrastructure director at Converteam, receives a prize from Steve Myers, Director of Accelerators at CERN, for the development and fabrication of the new electrical power system for the PS, called POPS.

  18. Pulse thermal processing of functional materials using directed plasma arc

    Science.gov (United States)

    Ott, Ronald D.; Blue, Craig A.; Dudney, Nancy J.; Harper, David C.

    2007-05-22

    A method of thermally processing a material includes exposing the material to at least one pulse of infrared light emitted from a directed plasma arc to thermally process the material, the pulse having a duration of no more than 10 s.

  19. Measurement of high-power microwave pulse under intense ...

    Indian Academy of Sciences (India)

    KALI-1000 pulse power system has been used to generate single pulse nanosecond duration high-power microwaves (HPM) from a virtual cathode oscillator (VIRCATOR) device. HPM power measurements were carried out using a transmitting–receiving system in the presence of intense high frequency (a few MHz) ...

  20. The OMERACT psoriatic arthritis magnetic resonance imaging scoring system (PsAMRIS): definitions of key pathologies, suggested MRI sequences, and preliminary scoring system for PsA Hands

    DEFF Research Database (Denmark)

    Østergaard, Mikkel; McQueen, Fiona; Wiell, Charlotte

    2009-01-01

    This article describes a preliminary OMERACT psoriatic arthritis magnetic resonance image scoring system (PsAMRIS) for evaluation of inflammatory and destructive changes in PsA hands, which was developed by the international OMERACT MRI in inflammatory arthritis group. MRI definitions of important...... pathologies in peripheral PsA and suggestions concerning appropriate MRI sequences for use in PsA hands are also provided....

  1. Laser-Induced Damage with Femtosecond Pulses

    Science.gov (United States)

    Kafka, Kyle R. P.

    The strong electric fields of focused femtosecond laser pulses lead to non-equilibrium dynamics in materials, which, beyond a threshold intensity, causes laser-induced damage (LID). Such a strongly non-linear and non-perturbative process renders important LID observables like fluence and intensity thresholds and damage morphology (crater) extremely difficult to predict quantitatively. However, femtosecond LID carries a high degree of precision, which has been exploited in various micro/nano-machining and surface engineering applications, such as human eye surgery and super-hydrophobic surfaces. This dissertation presents an array of experimental studies which have measured the damage behavior of various materials under femtosecond irradiation. Precision experiments were performed to produce extreme spatio-temporal confinement of the femtosecond laser-solid damage interaction on monocrystalline Cu, which made possible the first successful direct-benchmarking of LID simulation with realistic damage craters. A technique was developed to produce laser-induced periodic surface structures (LIPSS) in a single pulse (typically a multi-pulse phenomenon), and was used to perform a pump-probe study which revealed asynchronous LIPSS formation on copper. Combined with 1-D calculations, this new experimental result suggests more drastic electron heating than expected. Few-cycle pulses were used to study the LID performance and morphology of commercial ultra-broadband optics, which had not been systematically studied before. With extensive surface analysis, various morphologies were observed, including LIPSS, swelling (blisters), simple craters, and even ring-shaped structures, which varied depending on the coating design, number of pulses, and air/vacuum test environment. Mechanisms leading to these morphologies are discussed, many of which are ultrafast in nature. The applied damage behavior of multi-layer dielectric mirrors was measured and compared between long pulse (150 ps

  2. Pulsed-Light Inactivation of Food-Related Microorganisms

    OpenAIRE

    Rowan, N. J.; MacGregor, S. J.; Anderson, J. G.; Fouracre, R. A.; McIlvaney, L.; Farish, O.

    1999-01-01

    The effects of high-intensity pulsed-light emissions of high or low UV content on the survival of predetermined populations of Listeria monocytogenes, Escherichia coli, Salmonella enteritidis, Pseudomonas aeruginosa, Bacillus cereus, and Staphylococcus aureus were investigated. Bacterial cultures were seeded separately on the surface of tryptone soya-yeast extract agar and were reduced by up to 2 or 6 log10 orders with 200 light pulses (pulse duration, ∼100 ns) of low or high UV content, resp...

  3. Optimizing chirped laser pulse parameters for electron acceleration in vacuum

    Energy Technology Data Exchange (ETDEWEB)

    Akhyani, Mina; Jahangiri, Fazel; Niknam, Ali Reza; Massudi, Reza, E-mail: r-massudi@sbu.ac.ir [Laser and Plasma Research Institute, Shahid Beheshti University, Tehran 1983969411 (Iran, Islamic Republic of)

    2015-11-14

    Electron dynamics in the field of a chirped linearly polarized laser pulse is investigated. Variations of electron energy gain versus chirp parameter, time duration, and initial phase of laser pulse are studied. Based on maximizing laser pulse asymmetry, a numerical optimization procedure is presented, which leads to the elimination of rapid fluctuations of gain versus the chirp parameter. Instead, a smooth variation is observed that considerably reduces the accuracy required for experimentally adjusting the chirp parameter.

  4. Coherent amplification of ultrashort pulses in activated crystals

    Energy Technology Data Exchange (ETDEWEB)

    Varnavskii, O.P.; Kirkin, A.N.; Leontovich, A.M.; Malikov, R.F.; Mozharovskii, A.M.; Trifonov, E.D.

    1984-04-01

    Coherent amplification of picosecond pulses in Nd:YAG and ruby at a temperature of 100 K is investigated. The main features of coherent amplification which distinguish it from incoherent amplification are observed. Alternating sign oscillations of the field envelope at the trailing edge of the amplified pulse, unrestricted pulse duration in relation to the amplification line width, and a doublet structure in the emission spectrum were found. Good agreement was obtained between the experimental and theoretical results. 39 references.

  5. Experience of Pseudospark Switch Operation in Pulse Power Applications

    Science.gov (United States)

    Voitenko, N. V.; Yudin, A. S.; Kuznetsova, N. S.; Bochkov, V. D.

    2015-11-01

    The paper demonstrates the results of TDIl-200k/25SN-P pseudospark switch (PSS) developed by Russian company "Pulsed Technologies Ltd" application. PSS was used in pulsed power unit intended for electric-discharge fracture of rocks and concrete blocks and splitting off from monolith. The pulsed power unit has a pulse current generator with the capacity of 560 μF, stored energy of up to 63 kJ, operating voltage of up to15 kV, current pulse amplitude of up to 200 kA and pulse duration more than 200 μsec. The study also shows the current waveforms determined in the short-circuit experiment of the pulse current generator and in the experiments of the electric-discharge fragmentation of concrete at the charging voltage of 13 kV. PSS was operated in ringing single-pulse mode with the exceedance of more than two maximum permissible parameters: current pulse amplitude, current pulse duration and maximum pulse energy. Internal electrode erosion of PSS is shown and possible reasons of asymmetric current feed are discussed.

  6. Ultrashort X-ray pulse science

    Energy Technology Data Exchange (ETDEWEB)

    Chin, Alan Hap [Univ. of California, Berkeley, CA (US). Dept. of Physics; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    1998-05-01

    A variety of phenomena involves atomic motion on the femtosecond time-scale. These phenomena have been studied using ultrashort optical pulses, which indirectly probe atomic positions through changes in optical properties. Because x-rays can more directly probe atomic positions, ultrashort x-ray pulses are better suited for the study of ultrafast structural dynamics. One approach towards generating ultrashort x-ray pulses is by 90° Thomson scattering between terawatt laser pulses and relativistic electrons. Using this technique, the author generated ~ 300 fs, 30 keV (0.4 Å) x-ray pulses. These x-ray pulses are absolutely synchronized with ultrashort laser pulses, allowing femtosecond optical pump/x-ray probe experiments to be performed. Using the right-angle Thomson scattering x-ray source, the author performed time-resolved x-ray diffraction studies of laser-perturbated InSb. These experiments revealed a delayed onset of lattice expansion. This delay is due to the energy relaxation from a dense electron-hole plasma to the lattice. The dense electron-hole plasma first undergoes Auger recombination, which reduces the carrier concentration while maintaining energy content. Longitudinal-optic (LO) phonon emission then couples energy to the lattice. LO phonon decay into acoustic phonons, and acoustic phonon propagation then causes the growth of a thermally expanded layer. Source characterization is instrumental in utilizing ultrashort x-ray pulses in time-resolved x-ray spectroscopies. By measurement of the electron beam diameter at the generation point, the pulse duration of the Thomson scattered x-rays is determined. Analysis of the Thomson scattered x-ray beam properties also provides a novel means of electron bunch characterization. Although the pulse duration is inferred for the Thomson scattering x-ray source, direct measurement is required for other x-ray pulse sources. A method based on the laser-assisted photoelectric effect (LAPE) has been demonstrated as a

  7. Measurement of 2l-nl' x-ray transitions from approximately 1 microm Kr clusters irradiated by high-intensity femtosecond laser pulses.

    Science.gov (United States)

    Hansen, S B; Fournier, K B; Faenov, A Ya; Magunov, A I; Pikuz, T A; Skobelev, I Yu; Fukuda, Y; Akahane, Y; Aoyama, M; Inoue, N; Ueda, H; Yamakawa, K

    2005-01-01

    X-ray line emission from 2l-nl' transitions in Ne-like Kr and nearby ions has been observed from approximately 1 microm Kr clusters irradiated by fs-scale laser pulses at the JAERI facility in Kyoto, Japan. The incident laser intensity reached 10(19) W/cm2, with pulse energies from 50 to 300 mJ and pulse durations from 30 to 500 fs. The dependence of the x-ray spectral features and intensity on the incident laser intensity is rather weak, indicating that the 1-2 ps cluster lifetimes limit the number of ions beyond Ne-like Kr that can be produced by collisional ionization. Lines from F- to Al-like Kr emitted from the cluster plasmas have been identified using data from the relativistic multiconfiguration flexible atomic code. A collisional-radiative model based on these data has been constructed and used to determine that the cluster plasma has electron densities near 10(22) cm(-3), temperatures of a few hundred eV, and hot electron fractions of a few percent.

  8. [PS II photochemical efficiency in flag leaf of wheat varieties and its adaptation to strong sun- light intensity on farmland of Xiangride in Qinghai Province, Northwest China].

    Science.gov (United States)

    Shi, Sheng-Bo; Chen, Wen-Jie; Shi, Rui; Li, Miao; Zhang, Huai-Gang; Sun, Ya-Nan

    2014-09-01

    Taking four wheat varieties developed by Northwest Institute of Plateau Biology, Chinese Academy of Sciences, as test materials, with the measurement of content of photosynthetic pigments, leaf area, fresh and dry mass of flag leaf, the PS II photochemistry efficiency of abaxial and adaxial surface of flag leaf and its adaptation to strong solar radiation during the period of heading stage in Xiangride region were investigated with the pulse-modulated in-vivo chlorophyll fluorescence technique. The results indicated that flag leaf angle mainly grew in horizontal state in Gaoyuan 314, Gaoyuan 363 and Gaoyuan 584, and mainly in vertical state in Gaoyuan 913 because of its smaller leaf area and larger width. Photosynthetic pigments were different among the 4 varieties, and positively correlated with intrinsic PS II photochemistry efficiencies (Fv/Fm). In clear days, especially at noon, the photosynthetic photoinhibition was more serious in abaxial surface of flag leaf due to directly facing the solar radiation, but it could recover after reduction of sunlight intensity in the afternoon, which meant that no inactive damage happened in PS II reaction centers. There were significant differences of PS II actual and maximum photochemical efficiencies at the actinic light intensity (ΦPS II and Fv'/Fm') between abaxial and adaxial surface, and their relative variation trends were on the contrary. The photochemical and non-photochemical quenching coefficients (qP and NPQ) had a similar tendency in both abaxial and adaxial surfaces. Although ΦPS II and qP were lower in adaxial surface of flag leaf, the Fv'/Fm' was significantly higher, which indicated that the potential PS II capture efficiency of excited energy was higher. The results demonstrated that process of photochemical and non-photochemical quenching could effectively dissipate excited energy caused by strong solar radiation, and there were higher adaptation capacities in wheat varieties natively cultivated in

  9. Equivalent threshold sound pressure levels for acoustic test signals of short duration

    DEFF Research Database (Denmark)

    Poulsen, Torben; Daugaard, Carsten

    1998-01-01

    Hearing thresholds were measured for broadband clicks of 100 µs duration and for brief tones (0.500, 1, 2, 4, and 8 kHz). The signal shape of the tone pulses was of type 2-3-2, ie each pulse consisted of two periods of linear rise and fall and three periods with constant amplitude in between. The...

  10. Short optical pulse generated by integrated MQW DBR laser/EA-modulator

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Y.K.; Tanbun-Ek, T.; Logan, R.A. [AT and T Bell Labs., Murray Hill, NJ (United States)] [and others

    1994-12-31

    The authors report on the generation of short optical pulses by utilizing the non-linear absorption characteristics of a multiple quantum well (MQW) electro-absorption modulator, which is monolithically integrated with a MQW wavelength-tunable distributed Bragg reflector (DBR) laser on a single chip. Optical pulses as short as 39 ps and 15 ps have been generated at a repetition rate of 3 GHz and 10 GHz, respectively, with a broad tuning range of 5.4 nm near 1554 nm lasing wavelength.

  11. Laser ablation and photo-dissociation of solid-nitrogen film by UV ps-laser irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Niino, Hiroyuki; Sato, Tadatake; Narazaki, Aiko; Kawaguchi, Yoshizo; Yabe, Akira

    2002-09-30

    Nitrogen solid film deposited on a copper plate at 10 K was irradiated with a picosecond UV laser at 263 nm in vacuum. Photo-dissociation of nitrogen molecule in the solid film was confirmed by the optical emissions, which were ascribed to atomic nitrogen, during the laser irradiation at the fluence of 5 J cm{sup -2} pulse{sup -1}. This photolysis was discussed by the comparison with laser-induced breakdown of nitrogen gas. At the fluence over ca. 10 J cm{sup -2} pulse{sup -1}, the ablation of the frozen nitrogen film was observed. Employing the ablation plume including a reactive species such as nitrogen atoms, the surface reaction of a graphite (highly oted pyrolytic graphite (HOPG)) plate and silicon wafer was studied. XPS analysis indicated that nitrides were formed on the surfaces by the treatment. The ps-laser ablation of nitrogen solid film provides a novel technique for surface modification of materials.

  12. A new model for volume recombination in plane-parallel chambers in pulsed fields of high dose-per-pulse

    Science.gov (United States)

    Gotz, M.; Karsch, L.; Pawelke, J.

    2017-11-01

    In order to describe the volume recombination in a pulsed radiation field of high dose-per-pulse this study presents a numerical solution of a 1D transport model of the liberated charges in a plane-parallel ionization chamber. In addition, measurements were performed on an Advanced Markus ionization chamber in a pulsed electron beam to obtain suitable data to test the calculation. The experiment used radiation pulses of 4 μs duration and variable dose-per-pulse values up to about 1 Gy, as well as pulses of variable duration up to 308 μs at constant dose-per-pulse values between 85 mGy and 400 mGy. Those experimental data were compared to the developed numerical model and existing descriptions of volume recombination. At low collection voltages the observed dose-per-pulse dependence of volume recombination can be approximated by the existing theory using effective parameters. However, at high collection voltages large discrepancies are observed. The developed numerical model shows much better agreement with the observations and is able to replicate the observed behavior over the entire range of dose-per-pulse values and collection voltages. Using the developed numerical model, the differences between observation and existing theory are shown to be the result of a large fraction of the charge being collected as free electrons and the resultant distortion of the electric field inside the chamber. Furthermore, the numerical solution is able to calculate recombination losses for arbitrary pulse durations in good agreement with the experimental data, an aspect not covered by current theory. Overall, the presented numerical solution of the charge transport model should provide a more flexible tool to describe volume recombination for high dose-per-pulse values as well as for arbitrary pulse durations and repetition rates.

  13. Intense pulsed light (IPL): a review.

    Science.gov (United States)

    Babilas, Philipp; Schreml, Stephan; Szeimies, Rolf-Markus; Landthaler, Michael

    2010-02-01

    Intense pulsed light (IPL) devices use flashlamps and bandpass filters to emit polychromatic incoherent high-intensity pulsed light of determined wavelength spectrum, fluence, and pulse duration. Similar to lasers, the basic principle of IPL devices is a more or less selective thermal damage of the target. The combination of prescribed wavelengths, fluences, pulse durations, and pulse intervals facilitates the treatment of a wide spectrum of skin conditions. To summarize the physics of IPL, to provide guidance for the practical use of IPL devices, and to discuss the current literature on IPL in the treatment of unwanted hair growth, vascular lesions, pigmented lesions, acne vulgaris, and photodamaged skin and as a light source for PDT and skin rejuvenation. A systematic search of several electronic databases, including Medline and PubMed and the authors experience on intense pulsed light. Numerous trials show the effectiveness and compatibility of IPL devices. Most comparative trials attest IPLs similar effectiveness to lasers (level of evidence: 2b to 4, depending on the indication). However, large controlled and blinded comparative trials with an extended follow-up period are necessary.

  14. Induction Acceleration of a Single RF Bunch in the KEK PS

    CERN Document Server

    Takayama, Ken; Arakida, Yoshio; Horioka, Kazuhiko; Igarashi, Susumu; Iwashita, Taiki; Kawasaki, Atsushi; Kishiro, Junichi; Kono, Tadaaki; Koseki, Kunio; Nakamura, Eiji; Sakuda, Makoto; Sato, Hikaru; Shiho, Makoto; Shimosaki, Yoshito; Shirakata, Masashi; Sueno, Tsuyoshi; Tokuchi, Akira; Torikai, Kota; Toyama, Takeshi; Wake, Masayoshi; Watanabe, Masao; Yamane, Isao

    2005-01-01

    A single bunch trapped in an RF bucket was accelerated by induction devices from 500 MeV to 8GeV beyond transition energy in the KEK-PS. This is the first demonstration of induction acceleration in a high energy circular ring. The acceleration was confirmed by measuring a temporal evolution of the RF phase through an entire acceleration.* Key devices in an induction acceleration system are an induction accelerating cavity capable of generating an induced voltage of 2kV/cell, a pulse modulator to drive the cavity (switching driver), and a DSP system to control gate signals for switching. Their remarkable characteristics are its repetition ratio of about 1MHz and duty factor of 50%. All devices have been newly developed at KEK so as to meet this requirement. The pulse modulator employing MOSFETs as switching elements is connected with the accelerating cavity through a long transmission cable in order to avoid a high-dose irradiation in the accelerator tunnel. The induction system has been running beyond more th...

  15. Surface modification of collagen-based biomaterial induced by pulse width variable femtosecond laser pulses

    Science.gov (United States)

    Daskalova, A.; Selimis, A.; Manousaki, A.; Gray, D.; Ranella, A.; Fotakis, C.

    2013-03-01

    The ability to produce idealized cellular constructs is essential for understanding and controlling intercellular processes and ultimately for producing engineered tissue replacements. Preliminary results have been obtained on collagen modification by irradiation with single and multiple pulses of femtosecond laser with variable pulse duration. Irradiation of collagen thin film by single pulses of femtosecond duration results in creation of foam layer with micrometer thickness. The structure and thickness of the layer strongly depends on the number of the applied laser pulses. The surface properties of collagen thin films before and after Ti-sapphire irradiation with 800 nm were investigated by means of the technique Field Emission Scanning Electron Microscope (FESEM). Based on the FESEM results, it was possible to identify an energy density range as the ablation threshold for collagen thin films. The laser-induced foam formation was characterized over the intensity range 3 - 4.2x1011 W/cm2. The results of the field emission scanning electron microscopy, showed that by tailoring the laser pulse duration, improved the uniformity of the pore network. Examination of the interaction of ultra-short laser pulses with collagen films is useful for controlling the chemical and microstructural modification of the created foam layer.

  16. Optimization of protease production by an actinomycete Strain, PS ...

    African Journals Online (AJOL)

    Actinomycetes were isolated from the sediment samples of an estuarine shrimp pond located along the south east coast of India. During the investigation, a total of 28 strains of actinomycetes were isolated and examined for their protease activity. Among them, one strain PS-18A which was tentatively identified as ...

  17. Seismic receiver function interpretation: Ps splitting or anisotropic underplating?

    Science.gov (United States)

    Liu, Zhen; Park, Jeffrey

    2017-03-01

    Crustal anisotropy is crucial to understanding the evolutionary history of Earth's lithosphere. Shear wave splitting of Moho P-to-S converted phases in receiver functions (RFs) have been often used to study crustal anisotropy. Harmonic variation of Moho Ps phases in delay times are used to infer splitting parameters of averaged anisotropy in the crust. However, crustal anisotropy may distribute at various levels within the crust due to complex deformational processes. Layered anisotropy requires careful investigation of the distribution of anisotropy before interpreting Moho Ps splitting. In this study, we show results from stations ARU in Russia, KIP in the Hawaiian Islands and LSA in Tibetan Plateau, where layered anisotropy is constrained well by intracrust Ps conversions at high frequencies using a harmonic-decomposition technique. Anisotropic velocity models are inferred by forward-modeling decomposed RF waveforms. We suggest that the harmonic variation of Moho Ps phases should always be investigated to check for anisotropic layering using RFs with frequency content above 1 Hz, rather than simply reporting averaged anisotropy of the whole crust.

  18. Optimization of protease production by an actinomycete Strain, PS ...

    African Journals Online (AJOL)

    STORAGESEVER

    Isolation Agar Medium in duplicate Petri plates. To minimize ... on the Petri plates were counted from 5th day onwards, up to 28th .... After the dialysis, the volume was measured and analyzed for proteins and stored in deep freezer. Taxonomic investigation. The genus level identification was made for the strain PS-18A using ...

  19. Framing Retention for Institutional Improvement: A 4 Ps Framework

    Science.gov (United States)

    Kalsbeek, David H.

    2013-01-01

    A 4 Ps framework for student retention strategy is a construct for reframing the retention discussion in a way that enables institutional improvement by challenging some conventional wisdom and prevailing perspectives that have characterized retention strategy for years. It opens new possibilities for action and improvement by suggesting that…

  20. Multipole stack for the 4 rings of the PS Booster

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    The PS Booster (originally 800 MeV, now 1.4 GeV) saw first beam in 1972, routine operation began in 1973. The strive for ever higher intensities required the addition of multipoles. Manufacture of 8 stacks of multipoles was launched in 1974, for installation in 1976. For details, see 7511120X.

  1. The Swelling Behaviour of Polystyrene (PS)/ Polyvinylacetate (Pvac ...

    African Journals Online (AJOL)

    The effect of the variation of the type of solvent responsible for the differences in the swelling kinetics of Polystyrene (PS) and Polyvinyl acetate (PVAc) blends was studied. The results showed that the nature of solvent control or affects the degree of swelling. Also, 1-V characteristics at temperature range of 323-363K shows ...

  2. Boiling treatment of ABS and PS plastics for flotation separation.

    Science.gov (United States)

    Wang, Chong-qing; Wang, Hui; Wu, Bao-xin; Liu, Qun

    2014-07-01

    A new physical method, namely boiling treatment, was developed to aid flotation separation of acrylonitrile-butadiene-styrene (ABS) and polystyrene (PS) plastics. Boiling treatment was shown to be effective in producing a hydrophilic surface on ABS plastic. Fourier Transform Infrared analysis was conducted to investigate the mechanism of boiling treatment of ABS. Surface rearrangement of polymer may be responsible for surface change of boiling treated ABS, and the selective influence of boiling treatment on the floatability of boiling treated plastics may be attributed to the difference in the molecular mobility of polymer chains. The effects of flotation time, frother concentration and particle size on flotation behavior of simple plastic were investigated. Based on flotation behavior of simple plastic, flotation separation of boiling treatment ABS and PS with different particle sizes was achieved efficiently. The purity of ABS and PS was up to 99.78% and 95.80%, respectively; the recovery of ABS and PS was up to 95.81% and 99.82%, respectively. Boiling treatment promotes the industrial application of plastics flotation and facilitates plastic recycling. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Standardization of Rocket Engine Pulse Time Parameters

    Science.gov (United States)

    Larin, Max E.; Lumpkin, Forrest E.; Rauer, Scott J.

    2001-01-01

    Plumes of bipropellant thrusters are a source of contamination. Small bipropellant thrusters are often used for spacecraft attitude control and orbit correction. Such thrusters typically operate in a pulse mode, at various pulse lengths. Quantifying their contamination effects onto spacecraft external surfaces is especially important for long-term complex-geometry vehicles, e.g. International Space Station. Plume contamination tests indicated the presence of liquid phase contaminant in the form of droplets. Their origin is attributed to incomplete combustion. Most of liquid-phase contaminant is generated during the startup and shutdown (unsteady) periods of thruster pulse. These periods are relatively short (typically 10-50 ms), and the amount of contaminant is determined by the thruster design (propellant valve response, combustion chamber size, thruster mass flow rate, film cooling percentage, dribble volume, etc.) and combustion process organization. Steady-state period of pulse is characterized by much lower contamination rates, but may be lengthy enough to significantly conh'ibute to the overall contamination effect. Because there was no standard methodology for thruster pulse time division, plume contamination tests were conducted at various pulse durations, and their results do not allow quantifying contaminant amounts from each portion of the pulse. At present, the ISS plume contamination model uses an assumption that all thrusters operate in a pulse mode with the pulse length being 100 ms. This assumption may lead to a large difference between the actual amounts of contaminant produced by the thruster and the model predictions. This paper suggests a way to standardize thruster startup and shutdown period definitions, and shows the usefulness of this approach to better quantify thruster plume contamination. Use of the suggested thruster pulse time-division technique will ensure methodological consistency of future thruster plume contamination test programs

  4. Numerical Simulation and Analysis on 3D Temperature Field of the Metal Ablated with Femtosecond Pulse Laser

    Energy Technology Data Exchange (ETDEWEB)

    Yang Li; Yang Wei [Science College, Civil Aviation University of China, Tianjin 300300 (China); Wang Chingyue, E-mail: y_lyang@yahoo.com.cn [Key Laboratory of Opto-electronic Information Science and Technology, Ministry of Education, Tianjin University, Tianjin 300072 (China)

    2011-02-01

    To describe femtosecond laser ablation on the metal, numerical simulation on the basis of the double-temperature equation for three-dimension temperature field of the copper ablated with femtosecond pulse laser was performed by finite-difference method. Based on imbalance of the electronic and lattice's temperatures, the calefactive process of the electron and the lattice was obtained, respectively. The dependence of the electron-lattice coupling time on irradiated laser fluence was studied. The ablation depth and the ablation radius of the copper for single pulse fluence were calculated. The dependence of the start ablation (phase explosion arises) time of the copper on irradiated laser fluence was studied. The results indicate that the material jet due to phase explosion is earlier and the duration of ablation is longer with the increase of the laser fluence. When the laser fluence is higher than 1.5 J/cm{sup 2} the ablation start time is about 2-3 ps.

  5. Chirped-pulse programming of optical coherent transient true-time delays.

    Science.gov (United States)

    Merkel, K D; Babbitt, W R

    1998-04-01

    Programming an optical coherent transient true-time delay device with two frequency-chirped pulses provides a novel means of performing broadband (> >GHz) true-time delay with a wide dynamic range of delays with fine temporal resolution. We have demonstrated true-time delays exceeding 2micros with sub-100-ps resolution. Chirped-pulse programming has the advantages over the previously proposed brief pulse programming [Opt. Lett. 21 1102 (1996)] of reduced instantaneous power requirements and the ability to control the true-time delay by frequency shifting the programming pulses.

  6. psRNATarget: a plant small RNA target analysis server.

    Science.gov (United States)

    Dai, Xinbin; Zhao, Patrick Xuechun

    2011-07-01

    Plant endogenous non-coding short small RNAs (20-24 nt), including microRNAs (miRNAs) and a subset of small interfering RNAs (ta-siRNAs), play important role in gene expression regulatory networks (GRNs). For example, many transcription factors and development-related genes have been reported as targets of these regulatory small RNAs. Although a number of miRNA target prediction algorithms and programs have been developed, most of them were designed for animal miRNAs which are significantly different from plant miRNAs in the target recognition process. These differences demand the development of separate plant miRNA (and ta-siRNA) target analysis tool(s). We present psRNATarget, a plant small RNA target analysis server, which features two important analysis functions: (i) reverse complementary matching between small RNA and target transcript using a proven scoring schema, and (ii) target-site accessibility evaluation by calculating unpaired energy (UPE) required to 'open' secondary structure around small RNA's target site on mRNA. The psRNATarget incorporates recent discoveries in plant miRNA target recognition, e.g. it distinguishes translational and post-transcriptional inhibition, and it reports the number of small RNA/target site pairs that may affect small RNA binding activity to target transcript. The psRNATarget server is designed for high-throughput analysis of next-generation data with an efficient distributed computing back-end pipeline that runs on a Linux cluster. The server front-end integrates three simplified user-friendly interfaces to accept user-submitted or preloaded small RNAs and transcript sequences; and outputs a comprehensive list of small RNA/target pairs along with the online tools for batch downloading, key word searching and results sorting. The psRNATarget server is freely available at http://plantgrn.noble.org/psRNATarget/.

  7. Investigation on the Bimodal Distribution of the Duration of Gamma-ray Bursts from BATSE Light Curves

    OpenAIRE

    Yu, Wenfei; Li, Tipei; Wu, Mei

    1999-01-01

    We have investigated the bimodal distribution of the duration of BATSE gamma-ray bursts (GRBs) by analyzing light curves of 64 ms time resolution. We define the average pulse width of GRBs from the auto-correlation function of GRB profiles. The distribution of the average pulse width of GRBs is bimodal, suggesting that GRBs are composed of long-pulse GRBs and short-pulse GRBs. The average pulse width of long-pulse GRBs appears correlated with the peak flux, consistent with the time dilation e...

  8. Duration judgements over multiple elements

    Directory of Open Access Journals (Sweden)

    Inci eAyhan

    2012-11-01

    Full Text Available We investigated the limits of the number of events observers can simultaneously time. For single targets occurring in one of eight positions sensitivity to duration was improved for spatially pre-cued items as compared to post-cued items indicating that exogenous driven attention can improve duration discrimination. Sensitivity to duration for pre-cued items was also marginally better for single items as compared to eight items indicating that even after the allocation of focal attention, distracter items can interfere with the encoding of duration. For an eight item array discrimination was worse for post-cued locations as compared to pre-cued locations indicating both that attention can improve duration discrimination performance and that it was not possible to access a perfect memory trace of the duration of eight elements. The interference from the distracters in the pre-cued eight item array may reflect some mandatory averaging of target and distracter events. To further explore duration averaging we asked subjects to explicitly compare average durations of multiple item arrays against a single item standard duration. Duration discrimination thresholds were significantly lower for single elements as compared to multiple elements, showing that averaging, either automatically or intentionally, impairs duration discrimination. There was no set size effect. Performance was the same for averages of two and eight items, but performance with even an average of two items was worse than for one item. This was also true for sequential presentation indicating poor performance was not due to limits on the division of attention across items. Rather performance appears to be limited by an inability to remember or aggregate duration information from two or more items. Although it is possible to manipulate perceived duration locally, there appears to be no perceptual mechanisms for aggregating local durations across space.

  9. The role of a conserved membrane proximal cysteine in altering αPS2CβPS integrin diffusion

    Science.gov (United States)

    Syed, Aleem; Arora, Neha; Bunch, Thomas A.; Smith, Emily A.

    2016-12-01

    Cysteine residues (Cys) in the membrane proximal region are common post-translational modification (PTM) sites in transmembrane proteins. Herein, the effects of a highly conserved membrane proximal α-subunit Cys1368 on the diffusion properties of αPS2CβPS integrins are reported. Sequence alignment shows that this cysteine is palmitoylated in human α3 and α6 integrin subunits. Replacing Cys1368 in wild-type integrins with valine (Val1368) putatively blocks a PTM site and alters integrins’ ligand binding and diffusion characteristics. Both fluorescence recovery after photobleaching (FRAP) and single particle tracking (SPT) diffusion measurements show Val1368 integrins are more mobile compared to wild-type integrins. Approximately 33% and 8% more Val1368 integrins are mobile as measured by FRAP and SPT, respectively. The mobile Val1368 integrins also exhibit less time-dependent diffusion, as measured by FRAP. Tandem mass spectrometry data suggest that Cys1368 contains a redox or palmitoylation PTM in αPS2CβPS integrins. This membrane proximal Cys may play an important role in the diffusion of other alpha subunits that contain this conserved residue.

  10. Inductive Pulse Generation

    OpenAIRE

    Lindblom, Adam

    2006-01-01

    Pulsed power generators are a key component in compact systems for generation of high-power microwaves (HPM). HPM generation by virtual cathode devices such as Vircators put high demands on the source. The rise time and the pulse length of the source voltage are two key issues in the generation of HPM radiation. This thesis describes the construction and tests of several inductive high power pulse generators. The pulse generators were designed with the intent to deliver a pulse with fast rise...

  11. Evanescent field interaction of tapered fiber with graphene oxide in generation of wide-bandwidth mode-locked pulses

    Science.gov (United States)

    Ahmad, H.; Faruki, M. J.; Razak, M. Z. A.; Tiu, Z. C.; Ismail, M. F.

    2017-02-01

    Pulses with picosecond pulse widths are highly desired for high precision laser applications. A mode-locked pulse laser utilizing evanescent field interaction of a tapered fiber with graphene oxide (GO) is demonstrated. A homemade fabrication stage was used to fabricate the tapered fiber using systematic flame brushing and a GO solution was used to coat the microfiber using optical deposition technique. Pulse trains with a pulse width of 3.46 ps, a 3 dB optical bandwidth of 11.82 nm and a repetition rate of 920 kHz were obtained. The system has substantial potential for many crucial medical, communication, bio processing, military, and industrial applications.

  12. Construction of a pulsed MeV positron beam line

    Energy Technology Data Exchange (ETDEWEB)

    Masuno, Shin-ichi; Okada, Sohei; Kawasuso, Atsuo [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    To develop a fast (1 MeV) and short pulsed (100 ps) positron beam which enables defect behavior analysis of bulk states of materials even at high temperatures where a usual positron source would melt, we have been performing design study and construction of the beam line in a three-year program since 1994. This report describes the components, design study results and experimental results of the completed parts until now. (author)

  13. Ultrafast pulse generation with black phosphorus

    CERN Document Server

    Li, Diao; Karvonen, Lasse; Ye, Guojun; Lipsanen, Harri; Chen, Xianhui; Sun, Zhipei

    2015-01-01

    Black phosphorus has been recently rediscovered as a new and interesting two-dimensional material due to its unique electronic and optical properties. Here, we study the linear and nonlinear optical properties of black phosphorus thin films, indicating that both linear and nonlinear optical properties are anisotropic and can be tuned by the film thickness. Then we employ the nonlinear optical property of black phosphorus for ultrafast (pulse duration down to ~786 fs in mode-locking) and large-energy (pulse energy up to >18 nJ in Q-switching) pulse generation in fiber lasers at the near-infrared telecommunication band ~1.5 {\\mu}m. Our results underscore relatively large optical nonlinearity in black phosphorus and its prospective for ultrafast pulse generation, paving the way to black phosphorus based nonlinear and ultrafast photonics applications (e.g., ultrafast all-optical switches/modulators, frequency converters etc.).

  14. Simultaneous direct amplification and compression of picosecond pulses to 65-kW peak power without pulse break-up in erbium fiber.

    Science.gov (United States)

    Jasapara, J C; Andrejco, M J; Nicholson, J W; Yablon, A D; Várallyay, Z

    2007-12-24

    Picosecond pulses at 1.56 micro mm wavelength are directly amplified with a diffraction limited beam quality in a core-pumped Er fiber with an 875 micro m(2) effective area. The interplay between nonlinear spectral broadening and anomalous fiber dispersion compresses the input pulse duration during amplification so that 42 nJ energy pulses with approximately 65 kW peak power are achieved without pulse break-up.

  15. Pulse-train solutions and excitability in an optoelectronic oscillator

    Science.gov (United States)

    Rosin, D. P.; Callan, K. E.; Gauthier, D. J.; Schöll, E.

    2011-11-01

    We study an optoelectronic time-delay oscillator with bandpass filtering for different values of the filter bandwidth. Our experiments show novel pulse-train solutions with pulse widths that can be controlled over a three-order-of-magnitude range, with a minimum pulse width of ~150 ps. The equations governing the dynamics of our optoelectronic oscillator are similar to the FitzHugh-Nagumo model from neurodynamics with delayed feedback in the excitable and oscillatory regimes. Using a nullclines analysis, we derive an analytical proportionality between pulse width and the low-frequency cutoff of the bandpass filter, which is in agreement with experiments and numerical simulations. Furthermore, the nullclines help to describe the shape of the waveforms.

  16. Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment.

    Science.gov (United States)

    Olesen, Louise Ørum; Bouzinova, Elena V; Severino, Maurizio; Sivasaravanaparan, Mithula; Hasselstrøm, Jørgen Bo; Finsen, Bente; Wiborg, Ove

    2016-01-01

    Alzheimer's disease (AD) is a devastating illness characterized by a progressive loss of cognitive, social, and emotional functions, including memory impairments and more global cognitive deficits. Clinical-epidemiological evidence suggests that neuropsychiatric symptoms precede the onset of cognitive symptoms both in humans with early and late onset AD. The behavioural profile promoted by the AD pathology is believed to associate with degeneration of the serotonergic system. Using the APPswe/PS1δE9 model of AD-like pathology starting with 9 months old mice, we characterised long term non-cognitive behavioural changes measured at 9, 12, 15, and 18 months of age and applied principal component analysis on data obtained from open field, elevated plus maze, and social interaction tests. Long-term treatment with the selective serotonin reuptake inhibitor (SSRI) paroxetine was applied to assess the role of 5-HT on the behavioural profile; duration of treatment was 9 months, initiated when mice were 9 months of age. Treatment with paroxetine delays the decline in locomotion, in exploration and risk assessment behaviour, found in the APP/PS1 mice. APP/PS1 mice also exhibit low social activity and less aggressiveness, both of which are not affected by treatment with paroxetine. The APP/PS1 behavioural phenotype, demonstrated in this study, only begins to manifest itself from 12 months of age. Our results indicate that treatment with SSRI might ameliorate some of the behavioural deficits found in aged APP/PS1 mice.

  17. Nonresonant Multiple-Pulse Control of Molecular Motions in Liquid

    Directory of Open Access Journals (Sweden)

    Nikiforov V.G.

    2015-01-01

    Full Text Available We propose the implementation of the multiple-pulse excitation for manipulation of the molecular contributions to the optically-heterodyne-detected optical-Kerr-effect. The key parameters controlling the specificity of the multiple-pulse excitation scenarios are the pulses durations, the delays between pulses, the relation between the pump pulses amplitudes and the pulses polarizations. We model the high-order optical responses and consider some principles of the scenarios construction. We show that it is possible to adjust the excitation scenario in such a way that the some responses can be removed from detected signal along with the enhancement of the interested response amplitude. The theoretical analysis and first experimental data reveal that the multiple-pulse excitation technique can be useful for the selective spectroscopy of the molecular vibrations and rotations in liquid.

  18. An Advantage of the Equivalent Velocity Spectroscopy for Femtsecond Pulse Radiolysis

    CERN Document Server

    Kondoh, Takafumi; Tagawa, Seiichi; Tomosada, Hiroshi; Yang Jin Feng; Yoshida, Yoichi

    2005-01-01

    For studies of electron beam induced ultra-fast reaction process, femtosecond(fs) pulse radiolysis is under construction. To realize fs time resolution, fs electron and analyzing light pulses and their jitter compensation system are needed. About a 100fs electron pulse was generated by a photocathode RF gun linac and a magnetic pulse compressor. Synchronized Ti: Sapphire laser have a puleswidth about 160fs. And, it is significant to avoid degradation of time resolution caused by velocity difference between electron and analyzing light in a sample. In the 'Equivalent velocity spectroscopy' method, incident analyzing light is slant toward electron beam with an angle associated with refractive index of sample. Then, to overlap light wave front and electron pulse shape, electron pulse shape is slanted toward the direction of travel. As a result of the equivalent velocity spectroscopy for hydrated electrons, using slanted electron pulse shape, optical absorption rise time was about 1.4ps faster than normal electro...

  19. Three types of pulses delivered from a nanotube-mode-locked fiber laser

    Science.gov (United States)

    Yao, X. K.

    2015-07-01

    Three types of pulses are experimentally investigated in a switchable normal-dispersion nanotube-mode-locked fiber laser by adjusting polarizer controller and pump power. They are a standard dissipative-soliton (DS), conventional soliton (CS)-like pulse, and noiselike pulse, which correspond to three mode-locking states. The standard DS with a rectangular spectrum possesses a Gaussian-shape pulse. The CS-like operation has a Lorenz shape, and the spectrum involves several sidebands similar to the CS case. For the noiselike pulse with a bell-shaped spectrum, a 317 fs peak rides upon the 132.5 ps pedestal in the autocorrelation trace. The spectra of these three pulse operations are centered at three close wavelengths. The generation of three such different types of pulses in one identical normal- dispersion laser cavity may find an important application for the future of mode-locked laser research.

  20. Controllable delay of ultrashort pulses in a quantum dot optical amplifier

    DEFF Research Database (Denmark)

    Poel, Mike van der; Mørk, Jesper; Hvam, Jørn Märcher

    2005-01-01

    Optical and electrical tuning of the propagation time of 170 fs pulses in a quantum dot semiconductor amplifier at room temperature is demonstrated. Both pulse slowdown and advancement is possible and we achieve fractional delays (delay divided with pulse duration) of up to 40%. The results...... are explained by a simple gain saturation model....

  1. Pulse-periodic iodine photodissociation laser pumped with radiation from magnetoplasma compressors

    Science.gov (United States)

    Kashnikov, G. N.; Orlov, V. K.; Panin, A. N.; Piskunov, A. K.; Reznikov, V. A.

    1980-09-01

    The design and operation of an iodine photodissociation laser, pumped by radiation from magnetoplasma compressors, are described. The laser uses a closed-circulation system with C3F7I as the working gas. Repetitive-pulse operation has been achieved with an interval between pulses of 1 minute, a lasing energy of 110 J, and a pulse duration of 30 microseconds.

  2. Pulsed water jet generated by pulse multiplication

    Czech Academy of Sciences Publication Activity Database

    Dvorský, R.; Sitek, Libor; Sochor, T.

    2016-01-01

    Roč. 23, č. 4 (2016), s. 959-967 ISSN 1330-3651 R&D Projects: GA MŠk(CZ) LO1406; GA MŠk ED2.1.00/03.0082 Institutional support: RVO:68145535 Keywords : high-pressure pulses * pulse intensifier * pulsed water jet * water hammer effect Subject RIV: JQ - Machines ; Tools Impact factor: 0.723, year: 2016 http://hrcak.srce.hr/163752?lang=en

  3. [Retinal Cell Therapy Using iPS Cells].

    Science.gov (United States)

    Takahashi, Masayo

    2016-03-01

    Progress in basic research, starting with the work on neural stem cells in the middle 1990's to embryonic stem (ES) cells and induced pluripotent stem (iPS) cells at present, will lead the cell therapy (regenerative medicine) of various organs, including the central nervous system to a big medical field in the future. The author's group transplanted iPS cell-derived retinal pigment epithelial (RPE) cell sheets to the eye of a patient with exudative age-related macular degeneration (AMD) in 2014 as a clinical research. Replacement of the RPE with the patient's own iPS cell-derived young healthy cell sheet will be one new radical treatment of AMD that is caused by cellular senescence of RPE cells. Since it was the first clinical study using iPS cell-derived cells, the primary endpoint was safety judged by the outcome one year after surgery. The safety of the cell sheet has been confirmed by repeated tumorigenisity tests using immunodeficient mice, as well as purity of the cells, karyotype and genetic analysis. It is, however, also necessary to prove the safety by clinical studies. Following this start, a good strategy considering cost and benefit is needed to make regenerative medicine a standard treatment in the future. Scientifically, the best choice is the autologous RPE cell sheet, but autologous cell are expensive and sheet transplantation involves a risky part of surgical procedure. We should consider human leukocyte antigen (HLA) matched allogeneic transplantation using the HLA 6 loci homozyous iPS cell stock that Prof. Yamanaka of Kyoto University is working on. As the required forms of donor cells will be different depending on types and stages of the target diseases, regenerative medicine will be accomplished in a totally different manner from the present small molecule drugs. Proof of concept (POC) of photoreceptor transplantation in mouse is close to being accomplished using iPS cell-derived photoreceptor cells. The shortest possible course for treatment

  4. A transmissão psíquica geracional

    Directory of Open Access Journals (Sweden)

    Vinícius Oliveira dos Santos

    Full Text Available O artigo seguinte refere-se a um estudo sobre como ocorre a transmissão psíquica entre as gerações e qual sua importância na constituição psíquica do sujeito. É também objetivo deste artigo explicar o que são as transmissões intergeracional e transgeracional. Para buscar respostas para essas questões, fez-se uma pesquisa bibliográfica sobre a transmissão psíquica, pelo viés psicanalítico, principalmente a partir da teoria lacaniana e com conceitos oriundos da linguística saussuriana. Será a partir de uma determinada ordem simbólica, constituída pela linguagem que precede o sujeito, nomeado por Lacan como o Outro, que a transmissão psíquica entre gerações ganhará o seu caráter unívoco, sempre se tendo em mente a importância fundamental do recalcamento e de seus efeitos, bem como do retorno do recalcado nas diferentes gerações. A transmissão psíquica é necessária e concomitante à constituição do sujeito, e ocorre através da linguagem, dos significantes que irão determinar uma ordem simbólica para o ser que nasce através dos diferentes discursos que perpassam as gerações nas figuras dos pais desse novo ser. Essa ordem simbólica continuará a se fazer presente nesse novo sujeito pelo restante de sua existência. Este artigo busca dar nova luz ao aspecto da transmissão psíquica transgeracional, diferenciando-se da recalque s abordagens psicanalíticas contemporâneas por ser uma leitura lacaniana. Serão usados dois exemplos: um de como a transmissão aparece na cultura, outro, na subjetividade do sujeito através da arte.

  5. Generation of picosecond optical pulse based on chirp compensation

    Science.gov (United States)

    Sun, Xiaofeng; Yang, Jiaqian; Li, Shangyuan; Xue, Xiaoxiao; Zheng, Xiaoping; Zhou, Bingkun

    2017-10-01

    Picosecond optical pulses are widely used in optical communication systems, such as the optical time division multiplexing (OTDM) and photonic analog-to-digital converter (ADC). We have proposed and demonstrated a simple method to generate picosecond optical pulse using the mach-zehnder modulator (MZM), phase modulator (PM) and single model fiber (SMF). The phase modulator is used to generate a frequency chirp which varies periodically with time. The MZM is used to suppress the pedestal of the pulse and improve the performance of the pulse. The SMF is used to compensate the frequency chirp. We have carried out theoretical analysis and numerical simulation for the generation process of the picosecond optical pulse. The influence of phase shift between the modulation signals loaded on the MZM and PM is analyzed by numerical simulation and the conditions for the generation of picosecond optical pulse are given. The formula for calculating the optimum length of SMF which is used to compensate the linear chirp is given. The optical pulses with a repetition frequency of 10 GHz and a pulse width of 8.5 ps were obtained. The time-bandwidth product was as small as 1.09 and the timing jitter is as low as 83 fs.

  6. Laser-induced retinal damage threshold for repetitive-pulse exposure to 100-μs pulses

    Science.gov (United States)

    Lund, Brian J.; Lund, David J.; Edsall, Peter R.; Gaines, Victor D.

    2014-10-01

    The laser-induced retinal injury thresholds for repetitive-pulse exposures to 100-μs-duration pulses at a wavelength of 532 nm have been determined for exposures of up to 1000 pulses in an in vivo model. The ED50 was measured for pulse repetition frequencies of 50 and 1000 Hz. Exposures to collimated beams producing a minimal retinal beam spot and to divergent beams producing a 100-μm-diameter retinal beam spot were considered. The ED50 for a 100-μs exposure was measured to be 12.8 μJ total intraocular energy for a minimal retinal beam spot exposure and 18.1 μJ total intraocular energy for a 100-μm-diameter retinal beam spot. The threshold for exposures to N>1 pulse was found to be the same for both pulse repetition frequencies. The variation of the ED50 with the number of pulses is described well by the probability summation model, in which each pulse is considered an independent event. This is consistent with a threshold-level damage mechanism of microcavitation for single-pulse 100-μs-duration exposures. The data support the maximum permissible exposure levels for repetitive-pulse exposure promulgated in the most recent laser safety guidelines.

  7. Multi-channel, fiber-based seed pulse distribution system for femtosecond-level synchronized chirped pulse amplifiers.

    Science.gov (United States)

    Horáček, Martin; Indra, Lukáš; Green, Jonathan T; Naylon, Jack A; Tykalewicz, Boguslaw; Novák, Jakub; Batysta, František; Mazanec, Tomáš; Horáček, Jakub; Antipenkov, Roman; Hubka, Zbyněk; Boge, Robert; Bakule, Pavel; Rus, Bedřich

    2017-01-01

    We report on the design and performance of a fiber-based, multi-channel laser amplifier seed pulse distribution system. The device is designed to condition and distribute low energy laser pulses from a mode-locked oscillator to multiple, highly synchronized, high energy amplifiers integrated into a laser beamline. Critical functions such as temporal pulse stretching well beyond 100 ps/nm, pulse picking, and fine control over the pulse delay up to 300 ps are all performed in fiber eliminating the need for bulky and expensive grating stretchers, Pockels cells, and delay lines. These functions are characterized and the system as a whole is demonstrated by seeding two high energy amplifiers in the laser beamline. The design of this system allows for complete computer control of all functions, including tuning of dispersion, and is entirely hands-free. The performance of this device and its subsystems will be relevant to those developing lasers where reliability, size, and cost are key concerns in addition to performance; this includes those developing large-scale laser systems similar to ours and also those developing table-top experiments and commercial systems.

  8. EFFICACY OF IPL IN TREATMENT OF ACNE VULGARIS : COMPARISON OF SINGLE- AND BURST-PULSE MODE IN IPL

    OpenAIRE

    Kumaresan M; Srinivas C

    2010-01-01

    Background: Intense pulsed light (IPL) has been used for the treatment of facial acne. Modifications of various parameters allow flexibility in treatment, which include energy fluence, pulse duration, and pulse delay. We compared the efficacy of burst-pulse (multiple pulse) mode with single-pulse mode in treatment of acne. Objective: This study was designed to evaluate the efficacy of the IPL in treatment of facial acne and to compare burst-pulse and single-pulse mode in treatment of acne. Ma...

  9. Analysis of electromagnetic pulse (EMP measurements in the National Ignition Facility's target bay and chamber

    Directory of Open Access Journals (Sweden)

    Brown C.G.

    2013-11-01

    Full Text Available From May 2009 to the present we have recorded electromagnetic pulse (EMP strength and spectrum (100 MHz – 5 GHz in the target bay and chamber of the National Ignition Facility (NIF. The dependence of EMP strength and frequency spectrum on target type and laser energy is discussed. The largest EMP measured was for relatively low-energy, short-pulse (100 ps flat targets.

  10. Transfer line from the PSB to the PS (recombination)

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    After sequential ejection of 5 bunches from each of the 4 rings of the Booster (originally 800 MeV, now 1.4 GeV), the 4 batches are brought to the same vertical level, so as to form a string of 20 bunches, filling the circumference of the PS. This vertical "recombination" is performed in the transfer line, using vertical bending magnets, septa and kickers. Here we see the section where the beam from ring 4 (the top one) is brought down to the level of ring 3, and the beam from ring 1 up to the level of ring 2. Further downstream (to the right, outside this picture), level 2 is brought up to level 3, identical to that of the PS. After this original recombination scheme, other ways of combining the 4 beams, vertically and/or longitudinally, were developed and used in operation.

  11. O Trabalho Psíquico da Intersubjetividade

    Directory of Open Access Journals (Sweden)

    Maria Inês Assumpção Fernandes

    2003-01-01

    Full Text Available O presente trabalho procura refletir sobre o trabalho psíquico da intersubjetividade nos grupos. Trata-se de pensá-lo na relação com a ruptura de investimentos durante o processo de Transformação x Criação, em primeiro lugar. A partir desse ponto, discutiremos a relação entre Transformação, Trabalho e Dispositivo. Neste caso pensamos nas possibilidades de intervenção, refletindo sobre a intervenção inpidual e a intervenção grupal. A questão da Transmissão Psíquica entre gerações será focalizada, fundamentalmente, no que se refere aos tempos lógicos do recalque.

  12. Images of Christ's Saving Work in Ps.-Epiphanius' Homilies

    Directory of Open Access Journals (Sweden)

    H. F. Stander

    1997-12-01

    Full Text Available Images of Christ's Saving Work in Ps.-Epiphanius' Homilies. One cannot really speak of a systematic theology on the subject of atone-ment in the patristic writers. Frances Young once said that 'it is in fact impossible to categorize neatly the thought of the major patristic writers on the subject of atonement'. She adds that one cannot do justice to the range of motifs and images that are found in describing the saving and atoning work of Christ if we merely dismember 'systematic theologies' to illustrate common soteriological themes. One can only appreciate patristic views of atonement if one begins by recognizing the multifaceted unity of imagery that pervades the literature. This then is the goal of this article: to discuss the rich images which Ps: -Epiphanius uses to describe the atoning work of Christ.

  13. Magnetoelectric MnPS3 as a candidate for ferrotoroidicity

    Science.gov (United States)

    Ressouche, E.; Loire, M.; Simonet, V.; Ballou, R.; Stunault, A.; Wildes, A.

    2010-09-01

    We have revisited the magnetic structure of manganese phosphorus trisulfide MnPS3 using neutron diffraction and polarimetry. MnPS3 undergoes a transition toward a collinear antiferromagnetic order at 78 K. The resulting magnetic point-group breaks both the time reversal and the space inversion thus allowing a linear magnetoelectric coupling. Neutron polarimetry was subsequently used to prove that this coupling provides a way to manipulate the antiferromagnetic domains simply by cooling the sample under crossed magnetic and electrical fields, in agreement with the nondiagonal form of the magnetoelectric tensor. In addition, this tensor has, in principle, an antisymmetric part that results in a toroidic moment and provides with a pure ferrotoroidic compound.

  14. PS Dreyer: Bakens op die pad van die wetenskap

    Directory of Open Access Journals (Sweden)

    A. J. Antonites

    1986-01-01

    Full Text Available PS Dreyer: Beacons on the path of science Professor PS Dreyer is an academic who has shown insight and vision into several problems of the human sciences since 1951. He has identified problems, but also contributed solutions to them. In this respect his philosophy on causality and freedom is of utmost importance. The same applies to his investigations into the relationship history-Christianity as well as the unity of sciences and how the concepts scientific, unscientic and nonscientific are related to one another. His contribution to the understanding of Greek philosophy should be of significance for time to come. Two milestones could be distinguished: Dreyer's particular solution to the problem of the criterion on truth, viz meaningfulness and his notion of the knowledge of values in ethics by valuation in contradistinction to knowledge through feeling, reason and will.

  15. Images of Christ's Saving Work in Ps.-Epiphanius' Homilies

    Directory of Open Access Journals (Sweden)

    H. F. Stander

    1997-01-01

    Full Text Available Images of Christ's Saving Work in Ps.-Epiphanius' Homilies. One cannot really speak of a systematic theology on the subject of atone-ment in the patristic writers. Frances Young once said that 'it is in fact impossible to categorize neatly the thought of the major patristic writers on the subject of atonement'. She adds that one cannot do justice to the range of motifs and images that are found in describing the saving and atoning work of Christ if we merely dismember 'systematic theologies' to illustrate common soteriological themes. One can only appreciate patristic views of atonement if one begins by recognizing the multifaceted unity of imagery that pervades the literature. This then is the goal of this article: to discuss the rich images which Ps: -Epiphanius uses to describe the atoning work of Christ.

  16. Longitudinal coupled-bunch instability studies in the PS

    CERN Document Server

    Damerau, H

    2017-01-01

    The main longitudinal limitation for LHC-type beams inthe PS are coupled-bunch instabilities. A dedicated proto-typefeedbacksystemusingaFinemetcavityasalongitudinalkicker has been installed. Extensive tests with beam havebeen performed to explore the intensity reach with this feed-back. The maximum intensity with nominal longitudinalemittance at PS extraction has been measured, as well as theemittance required to keep the beam longitudinally stableat the design intensity for the High-Luminosity LHC (HL-LHC). A higher-harmonic cavity is a complementary op-tion to extend the intensity reach beyond the capabilities ofthe coupled-bunch feedback. Preliminary machine develop-ment (MD) studies operating one20MHzor one40MHzRF system as a higher harmonic at the flat-top indicate thebeneficial effect on longitudinal beam stability

  17. Rainfall intensity-duration equations

    Science.gov (United States)

    Froehlich, David C.

    1988-01-01

    A method for rapidly developing a rainfall intensity-duration equation for durations less than one hour and recurrence intervals between 2 and 100 years for any location in the conterminous United States is presented. Optimal parameters of a general rainfall-intensity duration equation are determined using precipitation depths for durations of 5, 10, 15, 30 and 60 minutes obtained from commonly available isopluvial maps. A single set of parameters applies to the entire western U.S. For the central and eastern U.S, a graphical means of determining the parameters is provided.

  18. Tensile Strength of Water Exposed to Pressure Pulses

    DEFF Research Database (Denmark)

    Andersen, Anders Peter; Mørch, Knud Aage

    2012-01-01

    at an extended water-solid interface by imposing a tensile stress pulse which easily causes cavitation. Next, a compressive pulse of duration ~1 ms and a peak intensity of a few bar is imposed prior to the tensile stress pulse. A dramatic increase of the tensile strength is observed immediately after...... the compressive pulse, but the effect is shortlived. We presume that diffusion of non-condensable gas from the cavitation nuclei into the liquid at compression, and back again later, is responsible for the changes of tensile strength....

  19. Duration dependence and heterogeneity in French youth unemployment durations

    NARCIS (Netherlands)

    Ours, van Jan C.; Berg, van den G.J.

    1996-01-01

    This paper investigates the degree in which the individual exit rate out of unemployment for young job seekers changes as a function of the elapsed unemployment duration. We use a nonparametric estimation method that is designed to be applicable to population data on outflows from different duration

  20. Functional characterization of calcineurin homologs PsCNA1/PsCNB1 in Puccinia striiformis f. sp. tritici using a host-induced RNAi system.

    Directory of Open Access Journals (Sweden)

    Hong Zhang

    Full Text Available Calcineurin plays a key role in morphogenesis, pathogenesis and drug resistance in most fungi. However, the function of calcineurin genes in Puccinia striiformis f. sp. tritici (Pst is unclear. We identified and characterized the calcineurin genes PsCNA1 and PsCNB1 in Pst. Phylogenetic analyses indicate that PsCNA1 and PsCNB1 form a calcium/calmodulin regulated protein phosphatase belonging to the calcineurin heterodimers composed of subunits A and B. Quantitative RT-PCR analyses revealed that both PsCNA1 and PsCNB1 expression reached their maximum in the stage of haustorium formation, which is one day after inoculation. Using barely stripe mosaic virus (BSMV as a transient expression vector in wheat, the expression of PsCNA1 and PsCNB1 in Pst was suppressed, leading to slower extension of fungal hyphae and reduced production of urediospores. The immune-suppressive drugs cyclosporin A and FK506 markedly reduced the germination rates of urediospores, and when germination did occur, more than two germtubes were produced. These results suggest that the calcineurin signaling pathway participates in stripe rust morphogenetic differentiation, especially the formation of haustoria during the early stage of infection and during the production of urediospores. Therefore PsCNA1 and PsCNB1 can be considered important pathogenicity genes involved in the wheat-Pst interaction.

  1. Consolidation of the 45-Year Old PS Main Magnet System

    CERN Document Server

    Zickler, Thomas; Kalbreier, Wilhelm; Mess, Karl Hubert; Newborough, Antony

    2006-01-01

    After a major coil insulation breakdown on two of the 47-year-old CERN PS main magnets in 2003, an extensive magnet consolidation program has been launched. This article reviews the analysis of the magnet state be-fore the repair and the applied major improvements. An overview is given of the production of the new compo-nents, the actual refurbishment and the commissioning of the main magnet system after 18 months shutdown.

  2. Specification of the Beam Position Measurement in the PS Machine

    CERN Document Server

    Bravin, Enrico; Chanel, M; Ludwig, M; Métral, Elias; Métral, G; Potier, J P; Raich, U; Scrivens, R; Steerenberg, R; CERN. Geneva. AB Department

    2003-01-01

    This specification, drawn up by the instrumentation specification board 2, describes the requirements concerning orbit and trajectory measurements in the PS machine. The orbit measurement and the trajectory measurement are both indispensable in order to be able to guarantee the correct beam quality for beams like LHC, the future Grand Sasso beam, the nTOF beam and surely the combined operation of the nTOF beam and the East Area beam.

  3. Science spin: iPS cell research in the news.

    Science.gov (United States)

    Caulfield, T; Rachul, C

    2011-05-01

    Big scientific developments have always been spun to meet particular social agendas. We have seen it in the context of global warming, nuclear power, and genetically modified organisms. But few stories illustrate the phenomenon of spin as well as the reaction, and concomitant media coverage, that surrounded the November 2007 announcement regarding the reprogramming of skin cells to produce cells with qualities comparable to those of human embryonic stem cells (hESCs) known as induced pluripotent stem (iPS) cells.

  4. Physics at the AD/PS/SPS (1/4)

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    Lecture 1: The CERN injector complex and beams for non-LHC physics. The various machines and beam lines in the CERN injector complex are presented, from the linacs to the SPS. Special emphasis is given to the beam lines at the PS and SPS machines: AD, North and East Areas, nTOF and CNGS and HiRadMad as well as the ion beams. A short outlook is given to possible future upgrades and projects.

  5. Ps18.pdf | sep2002 | jess | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; jess; sep2002; Ps18.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Associates – 2017. Posted on 17 July 2017. Click here to see the list · 28th Mid Year Meeting. Posted on 26 May ...

  6. New Electron Cloud Detectors for the PS Main Magnets

    CERN Document Server

    Yin Vallgren, Ch; Gilardoni, S; Taborelli, M; Neupert, H; Ferreira Somoza, J

    2014-01-01

    Electron cloud (EC) has already been observed during normal operation of the PS, therefore it is necessary to study its in fluence on any beam instability for the future LHC Injector Upgrade (LIU). Two new electron cloud detectors have been discussed, developed and installed during the Long Shutdown (LS1) in one of the PS main magnets. The first measurement method is based on current measurement by using a shielded button-type pick-up. Due to the geometry and space limitation in the PS magnet, the button-type pick-up made of a 96%Al2O3 block coated with a thin layer of solvent-based Ag painting, placed 30 degrees to the bottom part of the vacuum chamber was installed in the horizontal direction where the only opening of the magnet coil is. The other newly developed measurement method is based on detection of photons emitted by the electrons from the electron cloud impinging on the vacuum chamber walls. The emitted photons are reected to a quartz window. A MCP-PMT (Micro-Channel Plate Photomultiplier Tube) wit...

  7. LS1 Report: PS Booster prepares for beam

    CERN Multimedia

    Katarina Anthony

    2014-01-01

    With Linac2 already up and running, the countdown to beam in the LHC has begun! The next in line is the PS Booster, which will close up shop to engineers early next week. The injector will be handed over to the Operations Group who are tasked with getting it ready for active duty.   Taken as we approach the end of LS1 activities, this image shows where protons will soon be injected from Linac2 into the four PS Booster rings. Over the coming two months, the Operations Group will be putting the Booster's new elements through their paces. "Because of the wide range of upgrades and repairs carried out in the Booster, we have a very full schedule of tests planned for the machine," says Bettina Mikulec, PS Booster Engineer in Charge. "We will begin with cold checks; these are a wide range of tests carried out without beam, including system tests with power on/off and with varying settings, as well as verification of the controls system and timings." Amon...

  8. Picosecond Pulsed Laser Ablation for the Surface Preparation of Epoxy Composites

    Science.gov (United States)

    Palmieri, Frank; Ledesma, Rodolfo; Fulton, Tayler; Arthur, Alexandria; Eldridge, Keishara; Thibeault, Sheila; Lin, Yi; Wohl, Chris; Connell, John

    2017-01-01

    As part of a technical challenge under the Advanced Composites Program, methods for improving pre-bond process control for aerospace composite surface treatments and inspections, in conjunction with Federal Aviation Administration guidelines, are under investigation. The overall goal is to demonstrate high fidelity, rapid and reproducible surface treatment and surface characterization methods to reduce uncertainty associated with the bonding process. The desired outcomes are reliable bonded airframe structure, and reduced timeline to certification. In this work, laser ablation was conducted using a q-switched Nd:YVO4 laser capable of nominal pulse durations of 8 picoseconds (ps). Aerospace structural carbon fiber reinforced composites with an epoxy resin matrix were laser treated, characterized, processed into bonded assemblies and mechanically tested. The characterization of ablated surfaces were conducted using scanning electron microscopy (SEM), water contact angle (WCA) goniometry, micro laser induced breakdown spectroscopy (uLIBS), and electron spin resonance (ESR). The bond performance was assessed using a double cantilever beam (DCB) test with an epoxy adhesive. The surface characteristics and bond performance obtained from picosecond ablated carbon fiber reinforced plastics (CFRPs) are presented herein.

  9. Ramsey fringe width compared to the spectral width of the driving pulse pair

    Science.gov (United States)

    Supplee, James; Makhija

    2008-05-01

    In a population inversion versus detuning curve, fringes due to a Ramsey pulse-pair are vastly narrower than a peak due to just one of the pulses would be. For subtler reasons, the Ramsey fringe width is also less than the inversion peak that would be obtained using one long pulse with duration as long as the entire Ramsey pair including the time between pulses. This narrowing is by a factor of about 0.6 in many typical circumstances, but that factor can vary (sometimes significantly) depending on parameters such as pulse duration, pulse area, and time between pulses. We are doing calculations using an idealized semiclassical model with a two-level quantum system to address the following question: In which parameter regimes is the Ramsey fringe width well explained just by the spectral width of the driving pulse pair?

  10. Laser Pulses Characterization with Pyroelectric Sensors

    OpenAIRE

    Malka, V.; J. Faure; Y. Gauduel

    2010-01-01

    There are many industrial and medical applications of CO2 (λ=10.6 μm) and Nd:YAG (λ=1.06 μm) infrared lasers for which the quality of the process are tightly connected to the characteristic of the laser pulse. These two types of lasers deliver pulses with duration, repetition frequency and power that can be controlled by means of a programmable electronic control unit. An open-loop control generally optimize the process performances by availing of a laser system model. How...

  11. A pulse generator for xenon lamps

    CERN Document Server

    Janata, E

    2002-01-01

    A pulse generator is described, which enhances the analyzing light emitted from a xenon lamp as used in kinetic photospectrometry experiments. The lamp current is increased to 600 A for a duration of 3 ms; the current is constant within +-0.2% during a time interval of 2 ms. Because of instabilities of the lamp arc during pulsing, the use of the enhanced light source is limited to measuring times up to 500 mu s. The enhancement in light intensity depends on the wavelength and amounts to more than 400-fold in the UV-region.

  12. Kultuur isiksuse psühholoogiat ei mõjuta / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2010-01-01

    Psühholoogia uuemate andmete kohaselt ei sõltu indiviidi seadumus kultuurist, soost, vanusest, haridusest. Eesti psühholoogide Jüri Alliku ja Ann Realo osalusel ajakirjas "Journal Personality and Social Psychology" ilmunud artiklist

  13. Kultuur isiksuse psühholoogiat ei mõjuta / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2005-01-01

    Psühholoogia uuemate andmete kohaselt ei sõltu indiviidi seadumus kultuurist, soost, vanusest, haridusest. Eesti psühholoogide Jüri Alliku ja Anu Realo osalusel ajakirjas "Journal Personality and Social Psychology" ilmunud artiklist

  14. CO{sub 2} laser pulse shortening by laser ablation of a metal target

    Energy Technology Data Exchange (ETDEWEB)

    Donnelly, T.; Mazoyer, M.; Lynch, A.; O' Sullivan, G.; O' Reilly, F.; Dunne, P.; Cummins, T. [School of Physics, University College Dublin, Belfield, Dublin 4 (Ireland)

    2012-03-15

    A repeatable and flexible technique for pulse shortening of laser pulses has been applied to transversely excited atmospheric (TEA) CO{sub 2} laser pulses. The technique involves focusing the laser output onto a highly reflective metal target so that plasma is formed, which then operates as a shutter due to strong laser absorption and scattering. Precise control of the focused laser intensity allows for timing of the shutter so that different temporal portions of the pulse can be reflected from the target surface before plasma formation occurs. This type of shutter enables one to reduce the pulse duration down to {approx}2 ns and to remove the low power, long duration tails that are present in TEA CO{sub 2} pulses. The transmitted energy is reduced as the pulse duration is decreased but the reflected power is {approx}10 MW for all pulse durations. A simple laser heating model verifies that the pulse shortening depends directly on the plasma formation time, which in turn is dependent on the applied laser intensity. It is envisaged that this plasma shutter will be used as a tool for pulse shaping in the search for laser pulse conditions to optimize conversion efficiency from laser energy to useable extreme ultraviolet (EUV) radiation for EUV source development.

  15. A self-starting hybrid optoelectronic oscillator generating ultra low jitter 10-GHz optical pulses and low phase noise electrical signals

    DEFF Research Database (Denmark)

    Lasri, J.; Bilenca, A.; Dahan, D.

    2002-01-01

    In this letter, we describe a self-starting optical pulse source generating ultra low noise 15-ps-wide pulses at 10 GHz. It is based on a hybrid optoelectronic oscillator comprising a fiber extended cavity mode-locked diode laser which injection locks a self-oscillating heterojunction bipolar...

  16. Parabolic similariton Yb-fiber laser with triangular pulse evolution

    Science.gov (United States)

    Wang, Sijia; Wang, Lei

    2016-04-01

    We propose a novel mode-locked fiber laser design which features a passive nonlinear triangular pulse formation and self-similar parabolic pulse amplification intra cavity. Attribute to the nonlinear reshaping progress in the passive fiber, a triangular-profiled pulse with negative-chirp is generated and paved the way for rapid and efficient self-similar parabolic evolution in a following short-length high-gain fiber. In the meanwhile, the accompanied significantly compressed narrow spectrum from this passive nonlinear reshaping also gives the promise of pulse stabilization and gain-shaping robustness without strong filtering. The resulting short average intra-cavity pulse duration, low amplified spontaneous emission (ASE) and low intra-cavity power loss are essential for the low-noise operation. Simulations predict this modelocked fiber laser allows for high-energy ultra-short transform-limited pulse generation exceeding the gain bandwidth. The output pulse has a de-chirped duration (full-width at half maximum, FWHM) of 27 fs. In addition to the ultrafast laser applications, the proposed fiber laser scheme can support low-noise parabolic and triangular pulse trains at the same time, which are also attractive in optical pulse shaping, all-optical signal processing and high-speed communication applications.

  17. Compression of 200 GHz DWDM channelized TDM pulsed carrier from optically modelocking WRC-FPLD fiber ring at 10 GHz.

    Science.gov (United States)

    Lin, Yu-Chan; Peng, Guo-Hsuan; Lin, Gong-Ru

    2009-03-30

    The compression of 200GHz DWDM channelized optically mode-locking WRC-FPLD fiber ring pulse of at 10 GHz is performed for high-capacity TDM application. To prevent temporal and spectral cross-talk, the duty-cycle of the DWDM channelized WRC-FPLD FL pulse needs to be shortened without broadening its linewidth. With dual-cavity configuration induced DWDM channelization, a shortest single-channel WRC-FPLD FL pulsewidth of 19 ps is generated, which can be linearly compensated to 10 ps and fifth-order soliton compressed to 1.4 ps. Under a maximum pulsewidth compression ratio up to 14 and a +/-100 m tolerance on compressing fiber length, the single-channel pulsewidth remains DWDM channelized WRC-FPLD FL pulsed carrier is approaching 1% to satisfy at least 256 optical TDM channels.

  18. Comparative, validity and responsiveness of the HOOS-PS and KOOS-PS to the WOMAC physical function subscale in total joint replacement for osteoarthritis

    DEFF Research Database (Denmark)

    Davis, A M; Perruccio, A V; Canizares, M

    2009-01-01

    OBJECTIVE: To evaluate the internal consistency of the Hip disability and Osteoarthritis Outcome Score-Physical Function Short-form (HOOS-PS) and the Knee injury and Osteoarthritis Outcome Score-Physical Function Short-form (KOOS-PS) in total hip replacement (THR) and total knee (TKR) replacement....... Construct validity and responsiveness were compared to the Western Ontario McMaster Universities' Osteoarthritis Index (WOMAC) Likert 3.0 physical function (PF) subscale and the PF excluding the items in the short measures (PF-exclusions). METHODS: Participants completed the full HOOS or KOOS, measures...... of fatigue, anxiety, depression and the Chronic Pain Grade (CPG) pre-surgery and the HOOS or KOOS 6 months post-surgery. Internal consistency for the HOOS-PS and KOOS-PS was calculated using Cronbach's alpha. For construct validity, it was hypothesized that correlations between the HOOS-PS or KOOS-PS and PF...

  19. Highly selective dry etching of polystyrene-poly(methyl methacrylate) block copolymer by gas pulsing carbon monoxide-based plasmas

    Science.gov (United States)

    Miyazoe, Hiroyuki; Jagtiani, Ashish V.; Tsai, Hsin-Yu; Engelmann, Sebastian U.; Joseph, Eric A.

    2017-05-01

    We propose a very selective PMMA removal method from poly(styrene-block-methyl methacrylate) (PS-b-PMMA) copolymer using gas pulsing cyclic etching. Flow ratio of hydrogen (H2) added to carbon monoxide (CO) plasma was periodically changed to control etch and deposition processes on PS. By controlling the process time of each etch and deposition step, full PMMA removal including etching of the neutral layer was demonstrated at 28 nm pitch, while PS thickness remained intact. This is more than 10 times higher etch selectivity than conventional continuous plasma etch processes using standard oxygen (O2), CO-H2 and CO-O2-based chemistries.

  20. Analüütilised voolud psühholoogias ja nende rakendamine pedagoogikas / Aleksander Elango

    Index Scriptorium Estoniae

    Elango, Aleksander, 1902-2004

    2001-01-01

    Analüütise psühholoogia kolm koolkonda - S.Freudì koolkond e. päris-psühhoanalüüs, A.Adlerì koolkond e. individuaalpsühholoogia ja C.G.Jungì psühhoanalüüsi ja individuaalpsühholoogia sünteesi luua püüdev koolkond. Analüütise psühholoogia koolkondade ja pedagoogika suhetest

  1. Ultrabroadband 50-130 THz pulses generated via phase-matcheddifference frequency mixing in LiIO3

    Energy Technology Data Exchange (ETDEWEB)

    Zentgraf, Thomas; Huber, Rupert; Nielsen, Nils C.; Chemla, DanielS.; Kaindl, Robert A.

    2006-10-10

    We report the generation of ultrabroadband pulses spanningthe 50-130 THz frequency range via phase-matched difference frequencymixing within the broad spectrum of sub-10 fs pulses in LiIO_3. Modelcalculations reproduce the octave-spanning spectra and predict few-cycleTHz pulse durations less than 20~;fs. The applicability of this scheme isdemonstrated with 9-fs pulses from a Ti:sapphire oscillator and with 7-fsamplified pulses from a hollow fiber compressor as pumpsources.

  2. A comparative study of pulsed Nd:YAG and CO2 laser effect on cardiovascular tissue

    OpenAIRE

    Yova, D.; Papadakis, E.; Kassis, K.; Agapitos, E.; Kavantzas, N.; Koutsouris, D.; Serafetinidis, A.

    1994-01-01

    Percutaneous laser angioplasty is receiving increasing attention, as laser ablation of atheromatous plaque presents advantages to direct surgery or balloon angioplasty. One of the main prerequisites of using powerful pulsed lasers in angioplasty is the optimum choice of the irradiation parameters (the wavelength, the pulse shape and duration, the energy parameters e.t.c.). Infrared lasers have numerous applications in surgery. Among them the pulsed CO2 laser emitting at 10.6 µm and the pulsed...

  3. File list: His.PSC.05.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.PSC.05.AllAg.iPS_cells hg19 Histone Pluripotent stem cell iPS cells SRX317576,S...077,SRX317607 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.PSC.05.AllAg.iPS_cells.bed ...

  4. File list: His.PSC.50.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.PSC.50.AllAg.iPS_cells mm9 Histone Pluripotent stem cell iPS cells SRX977417,SR...RX127376,SRX146530,SRX146522,SRX146547,SRX333561,SRX035985,SRX1090869 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.PSC.50.AllAg.iPS_cells.bed ...

  5. File list: ALL.PSC.50.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.50.AllAg.iPS_cells hg19 All antigens Pluripotent stem cell iPS cells SRX088...16,SRX189400,SRX189399 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/ALL.PSC.50.AllAg.iPS_cells.bed ...

  6. File list: His.PSC.10.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.PSC.10.AllAg.iPS_cells hg19 Histone Pluripotent stem cell iPS cells SRX110016,S...315,SRX381309 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.PSC.10.AllAg.iPS_cells.bed ...

  7. File list: ALL.PSC.20.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.20.AllAg.iPS_cells hg19 All antigens Pluripotent stem cell iPS cells SRX088...27,SRX189400,SRX189399 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/ALL.PSC.20.AllAg.iPS_cells.bed ...

  8. File list: His.PSC.50.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.PSC.50.AllAg.iPS_cells hg19 Histone Pluripotent stem cell iPS cells SRX110015,S...079,SRX317585 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.PSC.50.AllAg.iPS_cells.bed ...

  9. File list: Pol.PSC.20.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.20.AllAg.iPS_cells mm9 RNA polymerase Pluripotent stem cell iPS cells SRX97...7435,SRX977434,SRX027462 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.20.AllAg.iPS_cells.bed ...

  10. File list: ALL.PSC.05.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.05.AllAg.iPS_cells hg19 All antigens Pluripotent stem cell iPS cells SRX753...00,SRX189399,SRX317607 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/ALL.PSC.05.AllAg.iPS_cells.bed ...

  11. File list: Pol.PSC.10.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.10.AllAg.iPS_cells mm9 RNA polymerase Pluripotent stem cell iPS cells SRX97...7435,SRX977434,SRX027462 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.10.AllAg.iPS_cells.bed ...

  12. File list: ALL.PSC.05.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.05.AllAg.iPS_cells mm9 All antigens Pluripotent stem cell iPS cells SRX9774...30,SRX146524,SRX146522,SRX146547 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.PSC.05.AllAg.iPS_cells.bed ...

  13. File list: Oth.PSC.50.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.PSC.50.AllAg.iPS_cells mm9 TFs and others Pluripotent stem cell iPS cells SRX97...RX146524 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.PSC.50.AllAg.iPS_cells.bed ...

  14. File list: Pol.PSC.50.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.50.AllAg.iPS_cells mm9 RNA polymerase Pluripotent stem cell iPS cells SRX97...7435,SRX977434,SRX027462 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.50.AllAg.iPS_cells.bed ...

  15. File list: DNS.PSC.20.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.PSC.20.AllAg.iPS_cells hg19 DNase-seq Pluripotent stem cell iPS cells SRX040379...,SRX040378,SRX135563,SRX040377,SRX040376,SRX189427,SRX189400,SRX189399 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.PSC.20.AllAg.iPS_cells.bed ...

  16. File list: DNS.PSC.10.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.PSC.10.AllAg.iPS_cells hg19 DNase-seq Pluripotent stem cell iPS cells SRX040379...,SRX040378,SRX040377,SRX040376,SRX135563,SRX189427,SRX189400,SRX189399 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.PSC.10.AllAg.iPS_cells.bed ...

  17. File list: Pol.PSC.05.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.05.AllAg.iPS_cells mm9 RNA polymerase Pluripotent stem cell iPS cells SRX97...7435,SRX027462,SRX977434 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.05.AllAg.iPS_cells.bed ...

  18. File list: ALL.PSC.10.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.10.AllAg.iPS_cells hg19 All antigens Pluripotent stem cell iPS cells SRX753...09,SRX189400,SRX189399 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/ALL.PSC.10.AllAg.iPS_cells.bed ...

  19. File list: His.PSC.10.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.PSC.10.AllAg.iPS_cells mm9 Histone Pluripotent stem cell iPS cells SRX977417,SR...RX127372,SRX1090869,SRX127376,SRX035977,SRX146530,SRX146547,SRX146522 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.PSC.10.AllAg.iPS_cells.bed ...

  20. File list: Oth.PSC.20.AllAg.iPS_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.PSC.20.AllAg.iPS_cells mm9 TFs and others Pluripotent stem cell iPS cells SRX97...RX146524 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.PSC.20.AllAg.iPS_cells.bed ...