WorldWideScience

Sample records for providing guidance monitoring

  1. 14 CFR 1263.110 - Intention to provide guidance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Intention to provide guidance. 1263.110 Section 1263.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DEMAND FOR INFORMATION OR TESTIMONY SERVED ON AGENCY EMPLOYEES; PROCEDURES § 1263.110 Intention to provide guidance. This...

  2. Providing global WLCG transfer monitoring

    CERN Document Server

    Andreeva, J; Campana, S; Flix, J; Flix, J; Keeble, O; Magini, N; Molnar, Z; Oleynik, D; Petrosyan, A; Ro, G; Saiz, P; Salichos, M; Tuckett, D; Uzhinsky, A; Wildish, T

    2012-01-01

    The WLCG[1] Transfers Dashboard is a monitoring system which aims to provide a global view of WLCG data transfers and to reduce redundancy in monitoring tasks performed by the LHC experiments. The system is designed to work transparently across LHC experiments and across the various technologies used for data transfer. Currently each LHC experiment monitors data transfers via experiment-specific systems but the overall cross-experiment picture is missing. Even for data transfers handled by FTS, which is used by 3 LHC experiments, monitoring tasks such as aggregation of FTS transfer statistics or estimation of transfer latencies are performed by every experiment separately. These tasks could be performed once, centrally, and then served to all experiments via a well-defined set of APIs. In the design and development of the new system, experience accumulated by the LHC experiments in the data management monitoring area is taken into account and a considerable part of the code of the ATLAS DDM Dashboard is being...

  3. 1999 vadose zone monitoring plan and guidance for subsequent years

    Energy Technology Data Exchange (ETDEWEB)

    Horton, D.G.; Reidel, S.P.; Last, G.V.

    1998-08-01

    The US Department of Energy`s Hanford Site has the most diverse and largest amounts of radioactive waste in the US. The majority of the liquid waste was disposed to the soil column where much of it remains today. This document provides the rationale and general framework for vadose zone monitoring at cribs, ditches, trenches and other disposal facilities to detect new sources of contamination and track the movement of existing contamination in the vadose zone for the protection of groundwater. The document provides guidance for subsequent site-specific vadose zone monitoring plans and includes a brief description of past vadose monitoring activities (Chapter 3); the results of the Data Quality Objective process used for this plan (Chapter 4); a prioritization of liquid waste disposal sites for vadose monitoring (Chapter 5 and Appendix B); a general Monitoring and Analysis Plan (Chapter 6); a general Quality Assurance Project Plan (Appendix A), and a description of vadose monitoring activities planned for FY 1999 (Appendix C).

  4. Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa.

    Science.gov (United States)

    Kishnani, Priya S; Rush, Eric T; Arundel, Paul; Bishop, Nick; Dahir, Kathryn; Fraser, William; Harmatz, Paul; Linglart, Agnès; Munns, Craig F; Nunes, Mark E; Saal, Howard M; Seefried, Lothar; Ozono, Keiichi

    2017-09-01

    Hypophosphatasia (HPP) is a rare, inherited, systemic, metabolic disorder caused by autosomal recessive mutations or a single dominant-negative mutation in the gene encoding tissue-nonspecific alkaline phosphatase (TNSALP). The disease is associated with a broad range of signs, symptoms, and complications, including impaired skeletal mineralization, altered calcium and phosphate metabolism, recurrent fractures, pain, respiratory problems, impaired growth and mobility, premature tooth loss, developmental delay, and seizures. Asfotase alfa is a human, recombinant enzyme replacement therapy that is approved in many countries for the treatment of patients with HPP. To address the unmet need for guidance in the monitoring of patients receiving asfotase alfa, an international panel of physicians with experience in diagnosing and managing HPP convened in May 2016 to discuss treatment monitoring parameters. The panel discussions focused on recommendations for assessing and monitoring patients after the decision to treat with asfotase alfa had been made and did not include recommendations for whom to treat. Based on the consensus of panel members, this review provides guidance on the monitoring of patients with HPP during treatment with asfotase alfa, including recommendations for laboratory, efficacy, and safety assessments and the frequency with which these should be performed during the course of treatment. Recommended assessments are based on patient age and include regular monitoring of biochemistry, skeletal radiographs, respiratory function, growth, pain, mobility and motor function, and quality of life. Because of the systemic presentation of HPP, a coordinated, multidisciplinary, team-based, patient-focused approach is recommended in the management of patients receiving asfotase alfa. Monitoring of efficacy and safety outcomes must be tailored to the individual patient, depending on medical history, clinical manifestations, availability of resources in the clinical

  5. Algorithm of trajectory guidance of a planning unmanned flight vehicle to a ground target providing the guidance in case the final conditions of guidance are given

    Directory of Open Access Journals (Sweden)

    О.Г. Водчиць

    2004-01-01

    Full Text Available  In the article are obtained the mathematical relations which allow to implement algorithm of trajectory guidance of a unmanned flight vehicle to a ground target providing the guidance in case the final conditions of guidance are given.

  6. Guidance Provided by Teacher and Simulation for Inquiry-Based Learning: a Case Study

    Science.gov (United States)

    Lehtinen, Antti; Viiri, Jouni

    2017-04-01

    Current research indicates that inquiry-based learning should be guided in order to achieve optimal learning outcomes. The need for guidance is even greater when simulations are used because of their high information content and the difficulty of extracting information from them. Previous research on guidance for learning with simulations has concentrated on guidance provided by the simulation. Little research has been done on the role of the teacher in guiding learners with inquiry-based activities using simulations. This descriptive study focuses on guidance provided during small group investigations; pre-service teachers ( n = 8) guided third and fifth graders using a particular simulation. Data was collected using screen capture videos. The data was analyzed using a combination of theory- and data-driven analysis. Forms of guidance provided by the simulation and by the teachers were divided into the same categories. The distribution of the guidance between the teacher and the simulation was also analyzed. The categories for forms of guidance provided by simulations proved to be applicable to guidance provided by the teachers as well. Teachers offered more various forms of guidance than the simulation. The teachers adapted their guidance and used different patterns to complement the guidance provided by the simulation. The results of the study show that guidance provided by teachers and simulations have different affordances, and both should be present in the classroom for optimal support of learning. This has implications for both teaching with simulations and development of new simulations.

  7. 78 FR 11654 - Draft Guidance for Industry and Food and Drug Administration Staff; Providing Information About...

    Science.gov (United States)

    2013-02-19

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration... Food, Drug, and Cosmetic Act; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... entitled ``Draft Guidance for Industry and Food and Drug Administration Staff: Providing Information About...

  8. Announcement: Guidance for U.S. Laboratory Testing for Zika Virus Infection: Implications for Health Care Providers.

    Science.gov (United States)

    2016-11-25

    CDC has released updated guidance online for U.S. laboratory testing for Zika virus infection. The guidance is available at https://www.cdc.gov/zika/laboratories/lab-guidance.html. Frequently asked questions are addressed at https://www.cdc.gov/zika/laboratories/lab-guidance-faq.html. This guidance updates recommendations for testing of specimens by U.S. laboratories for possible Zika virus infection. Major updates to the guidance with clinical implications for health care providers include the following.

  9. Towards a biological monitoring guidance value for acrylamide.

    Science.gov (United States)

    Sams, C; Jones, K; Warren, N; Cocker, J; Bell, S; Bull, P; Cain, M

    2015-08-19

    Acrylamide is classified as a potential human carcinogen and neurotoxicant. Biological monitoring is a useful tool for monitoring worker exposure. However, other sources of exposure to acrylamide (including cigarette smoke and diet) also need to be considered. This study has performed repeat measurements of the urinary mercapturic acids of acrylamide (AAMA) and its metabolite glycidamide (GAMA) and determined globin adducts in 20 production-plant workers at a UK acrylamide production facility. The relationship between biomarker levels and environmental monitoring data (air levels and hand washes) was investigated. Good correlations were found between all of the biomarkers (r(2)=0.86-0.91) and moderate correlations were found between the biomarkers and air levels (r(2) = 0.56-0.65). Our data show that urinary AAMA is a reliable biomarker of acrylamide exposure. Occupational hygiene data showed that acrylamide exposure at the company was well within the current UK Workplace Exposure Limit. The 90th percentile of urinary AAMA in non-smoking production-plant workers (537 μmol/mol creatinine (n = 59 samples)) is proposed as a possible biological monitoring guidance value. This 90th percentile increased to 798 μmol/mol if smokers were included (n = 72 samples). These values would be expected following an airborne exposure of less than 0.07 mg/m(3), well below the current UK workplace exposure limit of 0.3mg/m(3). Comparison of biomarker levels in non-occupationally exposed individuals suggests regional variations (between UK and Germany), possibly due to differences in diet. Crown Copyright © 2015. Published by Elsevier Ireland Ltd. All rights reserved.

  10. 78 FR 310 - Draft Revision of Guidance for Industry on Providing Regulatory Submissions in Electronic Format...

    Science.gov (United States)

    2013-01-03

    ... Doc No: 2012-31577] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-1256] Draft Revision of Guidance for Industry on Providing Regulatory Submissions in... Electronic Common Technical Document Specifications; Availability AGENCY: Food and Drug Administration, HHS...

  11. OPP Guidance for Submission of State and Tribal Water Quality Monitoring Data

    Science.gov (United States)

    This guidance describes the process to submit state and tribal surface and groundwater monitoring data for consideration in exposure characterizations for ecological and and human health risk assessments and in risk management decisions for pesticides.

  12. Periodic Monitoring Guidance for Title V Operating Permits Programs

    Science.gov (United States)

    This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  13. Spectral tissue sensing for guidance and monitoring in oncological procedures

    NARCIS (Netherlands)

    Spliethoff, Jarich

    2015-01-01

    The emergence of minimally invasive diagnostic and interventional procedures has increased the demand for real time guidance for a variety of oncological applications that rely on accurate instrument positioning and procedural feedback. In this thesis we described the results of various preclinical

  14. 78 FR 44573 - Guidance for Industry on Providing Submissions in Electronic Format-Postmarket Non-Expedited...

    Science.gov (United States)

    2013-07-24

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry on Providing Submissions in Electronic...; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of a guidance to industry entitled ``Providing Submissions in...

  15. The effectiveness of baby books for providing pediatric anticipatory guidance to new mothers.

    Science.gov (United States)

    Reich, Stephanie M; Bickman, Leonard; Saville, Benjamin R; Alvarez, Joann

    2010-05-01

    To assess whether embedding pediatric anticipatory guidance into books read to infants is an effective way to educate low-income, first-time mothers about injury-prevention and health-promotion practices. Primiparous women (N = 168) were randomly assigned to 1 of 3 groups: an educational-book group; a noneducational-book group; or a no-book group. Knowledge of anticipatory-guidance topics regarding children from birth to 12 months of age (eg, injury prevention, parenting, nutrition) was assessed during the third trimester of pregnancy and again when infants were approximately 2, 4, 6, 9, 12, and 18 months of age. Women in the educational-book group scored consistently higher on knowledge than did those in the other 2 groups. Those in the educational-book group were found to have significantly higher knowledge scores than those in both the noneducational-book group (effect size [ES]: 0.3, P book group (ES: 0.3, P Books read by mothers to infants seem to be an effective way to provide anticipatory guidance to new mothers. However, future work is needed to determine if increased knowledge translates into safer and more developmentally appropriate parenting practices.

  16. Mobile phone-based clinical guidance for rural health providers in India.

    Science.gov (United States)

    Gautham, Meenakshi; Iyengar, M Sriram; Johnson, Craig W

    2015-12-01

    There are few tried and tested mobile technology applications to enhance and standardize the quality of health care by frontline rural health providers in low-resource settings. We developed a media-rich, mobile phone-based clinical guidance system for management of fevers, diarrhoeas and respiratory problems by rural health providers. Using a randomized control design, we field tested this application with 16 rural health providers and 128 patients at two rural/tribal sites in Tamil Nadu, Southern India. Protocol compliance for both groups, phone usability, acceptability and patient feedback for the experimental group were evaluated. Linear mixed-model analyses showed statistically significant improvements in protocol compliance in the experimental group. Usability and acceptability among patients and rural health providers were very high. Our results indicate that mobile phone-based, media-rich procedural guidance applications have significant potential for achieving consistently standardized quality of care by diverse frontline rural health providers, with patient acceptance. © The Author(s) 2014.

  17. 78 FR 48173 - Guidance for Industry on Oversight of Clinical Investigations-A Risk-Based Approach to Monitoring...

    Science.gov (United States)

    2013-08-07

    ... No. FDA-2011-D-0597] Guidance for Industry on Oversight of Clinical Investigations--A Risk-Based... entitled ``Oversight of Clinical Investigations--A Risk-Based Approach to Monitoring.'' This guidance... human drugs, biologics, medical devices, and combinations thereof. The overarching goal of this guidance...

  18. Guidance Provided by Teacher and Simulation for Inquiry-Based Learning: A Case Study

    Science.gov (United States)

    Lehtinen, Antti; Viiri, Jouni

    2017-01-01

    Current research indicates that inquiry-based learning should be guided in order to achieve optimal learning outcomes. The need for guidance is even greater when simulations are used because of their high information content and the difficulty of extracting information from them. Previous research on guidance for learning with simulations has…

  19. Guidance values for surface monitoring of antineoplastic drugs in German pharmacies.

    Science.gov (United States)

    Schierl, Rudolf; Böhlandt, Antje; Nowak, Dennis

    2009-10-01

    Antineoplastic drugs are widely used in anticancer therapy due to their cytotoxic activity but many of them are classified as carcinogenic, mutagenic, or teratogenic to humans. In order to evaluate personal exposure, surface monitoring has been successfully applied for several years. In this study, we present a statistical description of our data set from 102 German pharmacies and propose 'threshold guidance values (TGVs)' to facilitate interpretation of monitoring results. Our database included 1008 results for platinum (PT) and 1237 for 5-fluorouracil (FU) collected in 102 pharmacies in Germany. Wipe sampling on site was performed with one validated procedure. PT concentrations were measured by voltammetry and FU by gas chromatography/mass spectrometry. Data were stratified into 10 locations and statistically evaluated. Contamination was detected on all surfaces in the pharmacies with high levels on storage shelves and floors. The median values for the different locations ranged from 0.20 to 1.70 pg cm(-2) (mean: 0.57 pg cm(-2)) for PT and from 2.50 to 10.00 pg cm(-2) (mean: 5.34 pg cm(-2)) for FU. The mean 75th percentiles were 3.92 pg cm(-2) (PT) and 28.90 pg cm(-2) (FU). The TGV 1 value was set at the median value and results below demonstrate good working practices. Contaminations above the TGV 2, which was assigned at the 75th percentile, show a clear need for optimizing the handling procedures. The introduction of TGVs helps to reduce occupational exposure and allows pharmacy personnel to benchmark their own contamination levels. This provides a basis for improvement in occupational safety precautions and for regular contamination controls.

  20. Statistics provide guidance for indigenous organic carbon detection on Mars missions.

    Science.gov (United States)

    Sephton, Mark A; Carter, Jonathan N

    2014-08-01

    Data from the Viking and Mars Science Laboratory missions indicate the presence of organic compounds that are not definitively martian in origin. Both contamination and confounding mineralogies have been suggested as alternatives to indigenous organic carbon. Intuitive thought suggests that we are repeatedly obtaining data that confirms the same level of uncertainty. Bayesian statistics may suggest otherwise. If an organic detection method has a true positive to false positive ratio greater than one, then repeated organic matter detection progressively increases the probability of indigeneity. Bayesian statistics also reveal that methods with higher ratios of true positives to false positives give higher overall probabilities and that detection of organic matter in a sample with a higher prior probability of indigenous organic carbon produces greater confidence. Bayesian statistics, therefore, provide guidance for the planning and operation of organic carbon detection activities on Mars. Suggestions for future organic carbon detection missions and instruments are as follows: (i) On Earth, instruments should be tested with analog samples of known organic content to determine their true positive to false positive ratios. (ii) On the mission, for an instrument with a true positive to false positive ratio above one, it should be recognized that each positive detection of organic carbon will result in a progressive increase in the probability of indigenous organic carbon being present; repeated measurements, therefore, can overcome some of the deficiencies of a less-than-definitive test. (iii) For a fixed number of analyses, the highest true positive to false positive ratio method or instrument will provide the greatest probability that indigenous organic carbon is present. (iv) On Mars, analyses should concentrate on samples with highest prior probability of indigenous organic carbon; intuitive desires to contrast samples of high prior probability and low prior

  1. 75 FR 69449 - Draft Guidance for Industry and Food and Drug Administration Staff on Dear Health Care Provider...

    Science.gov (United States)

    2010-11-12

    ... Staff on Dear Health Care Provider Letters: Improving Communication of Important Safety Information... Administration (FDA) is announcing the availability of a draft guidance for industry and FDA staff entitled... include in a DHCP letter, how to organize that information, and formatting techniques to make the...

  2. Vertebroplasty and kyphoplasty in the United States: provider distribution and guidance method, 2001-2010.

    Science.gov (United States)

    Long, Suzanne S; Morrison, William B; Parker, Laurence

    2012-12-01

    The purpose of this study was to determine the utilization by specialty and guidance method for vertebral augmentation (including vertebroplasty and kyphoplasty) in the United States from 2001 to 2010. Using the 2001 through 2010 United States part B Medicare claims database, we studied the CPT-4 (Current Procedural Terminology, 4th ed.) codes used for thoracic (22520) and lumbar (22521) vertebroplasty, thoracic (22523) and lumbar (22524) kyphoplasty, and the method of radiologic guidance (76012 for fluoroscopy and 76013 for CT). For each of these codes, volume and physician specialty were tabulated. Radiologists performed 73% of Medicare-reimbursed vertebroplasty procedures in the United States in 2001-2010 and 30% of kyphoplasty procedures from 2006 to 2010. The majority were performed by nonradiologists, most notably orthopedic surgeons, who accounted for 40%. Although there was a decrease in utilization of vertebroplasty and kyphoplasty from 2009 to 2010, the number of vertebroplasties increased by 72.9% from 2001 to 2010, and the number of kyphoplasties increased by 12.0% from 2006 to 2010. Fluoroscopy is nearly universal as a guidance method for both vertebroplasty and kyphoplasty. This study shows that despite controversy regarding the long-term efficacy of vertebral augmentation, including vertebroplasty and kyphoplasty, utilization has risen since these procedures have been instituted and fluoroscopy is nearly universal as a guidance method. For vertebroplasty, the decrease in utilization from 2007 to 2009 may be explained in part by a combination of the initiation of kyphoplasty codes in 2006 and the August 2009 Kallmes et al. and Buchbinder et al. publications. Decreased utilization of both vertebroplasty and kyphoplasty from 2009 to 2010 may also be partly due to these publications.

  3. 5 CFR 9701.407 - Monitoring performance and providing feedback.

    Science.gov (United States)

    2010-01-01

    ... implementing directives and policies, supervisors must— (a) Monitor the performance of their employees and the organization; and (b) Provide timely periodic feedback to employees on their actual performance with respect to their performance expectations, including one or more interim performance reviews during each appraisal...

  4. Metaboli-Net: online groupware system providing counseling guidance for patients with metabolic syndrome.

    Science.gov (United States)

    Kuwata, Shigeki; Taniguchi, Shin-ichi; Kato, Atsuko; Inoue, Kazuoki; Yamamoto, Naoya; Ohkura, Tsuyoshi; Teramoto, Kei; Shigemasa, Chiaki; Kondoh, Hiroshi

    2010-01-01

    This study presented a newly developed online groupware system, Metaboli-Net, to yield counseling guidance on diet and exercise to patients with metabolic syndrome. A distinctive feature adopted in the system to maintain the retention rate of patients was the social network service (SNS) that enables the patients to share their dietary and relevant health information with other participants in the same group on the network. A pilot study was conducted to prove the effectiveness of the system in improving the patient's lifestyle and dietary health awareness. SNS also contributed to the participant's adherence to intervention programs.

  5. Site Screening and Technical Guidance for Monitored Natural Attenuation at DOE Sites

    Energy Technology Data Exchange (ETDEWEB)

    Borns, D.J.; Brady, P.V.; Brady, W.D.; Krupka, K.M.; Spalding, B.P.; Waters, R.D.; Zhang, P.

    1999-03-01

    Site Screening and Technical Guidance for Monitored Natural Attenuation at DOE Sites briefly outlines the biological and geochemical origins of natural attenuation, the tendency for natural processes in soils to mitigate contaminant transport and availability, and the means for relying on monitored natural attenuation (MNA) for remediation of contaminated soils and groundwaters. This report contains a step-by-step guide for (1) screening contaminated soils and groundwaters on the basis of their potential for remediation by natural attenuation and (2) implementing MNA consistent with EPA OSWER Directive 9200.4-17. The screening and implementation procedures are set up as a web-based tool (http://www.sandia.gov/eesector/gs/gc/na/mnahome.html) to assist US Department of Energy (DOE) site environmental managers and their staff and contractors to adhere to EPA guidelines for implementing MNA. This document is intended to support the Decision Maker's Framework Guide and Monitoring Guide both to be issued from DOE EM-40. Further technical advances may cause some of the approach outlined in this document to change over time.

  6. Respiratory Protection Toolkit: Providing Guidance Without Changing Requirements-Can We Make an Impact?

    Science.gov (United States)

    Bien, Elizabeth Ann; Gillespie, Gordon Lee; Betcher, Cynthia Ann; Thrasher, Terri L; Mingerink, Donna R

    2016-12-01

    International travel and infectious respiratory illnesses worldwide place health care workers (HCWs) at increasing risk of respiratory exposures. To ensure the highest quality safety initiatives, one health care system used a quality improvement model of Plan-Do-Study-Act and guidance from Occupational Safety and Health Administration's (OSHA) May 2015 Hospital Respiratory Protection Program (RPP) Toolkit to assess a current program. The toolkit aided in identification of opportunities for improvement within their well-designed RPP. One opportunity was requiring respirator use during aerosol-generating procedures for specific infectious illnesses. Observation data demonstrated opportunities to mitigate controllable risks including strap placement, user seal check, and reuse of disposable N95 filtering facepiece respirators. Subsequent interdisciplinary collaboration resulted in other ideas to decrease risks and increase protection from potentially infectious respiratory illnesses. The toolkit's comprehensive document to evaluate the program showed that while the OSHA standards have not changed, the addition of the toolkit can better protect HCWs. © 2016 The Author(s).

  7. Compliance Assurance Monitoring Technical Guidance Document Appendix A: Electrostatic Precipitator Control Device

    Science.gov (United States)

    Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

  8. Compliance Assurance Monitoring Technical Guidance Document Appendix A: Wet Electrostatic Precipitator Control Device

    Science.gov (United States)

    Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

  9. Nutrition: Intervention Guidance for Service Providers and Families. Connecticut Birth to Three System, Service Guideline 6.

    Science.gov (United States)

    Connecticut Birth to Three System, Hartford.

    This guide was developed to assist families and service providers in Connecticut with nutrition services for infants and toddlers with disabilities. Individual sections provide information about the following topics: laws and regulations related to nutrition services; eligibility for the Connecticut Birth to Three System and nutrition; nutrition…

  10. A Surgical Robot Teleoperation Framework for Providing Haptic Feedback Incorporating Virtual Environment-Based Guidance

    OpenAIRE

    Munawar, Adnan; Fischer, Gregory

    2016-01-01

    In robot-assisted teleoperated laparoscopic surgeries, the patient side manipulators are controlled via the master manipulators, operated by the surgeon. The current generation of robots approved for laparoscopic surgery lack haptic feedback. In theory, haptic feedback could enhance the surgical procedures by providing a palpable sense of the environment as a function of surgeon’s hands movements. This research presents an overall control framework for haptic feedback on existing robot platfo...

  11. Continuous monitoring of prostate position using stereoscopic and monoscopic kV image guidance

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, M. Tynan R.; Parsons, Dave D.; Robar, James L. [Department of Medical Physics, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada and Nova Scotia Cancer Centre, QEII Health Science Centre, Halifax, Nova Scotia B3H 2Y9 (Canada)

    2016-05-15

    Purpose: To demonstrate continuous kV x-ray monitoring of prostate motion using both stereoscopic and monoscopic localizations, assess the spatial accuracy of these techniques, and evaluate the dose delivered from the added image guidance. Methods: The authors implemented both stereoscopic and monoscopic fiducial localizations using a room-mounted dual oblique x-ray system. Recently developed monoscopic 3D position estimation techniques potentially overcome the issue of treatment head interference with stereoscopic imaging at certain gantry angles. To demonstrate continuous position monitoring, a gold fiducial marker was placed in an anthropomorphic phantom and placed on the Linac couch. The couch was used as a programmable translation stage. The couch was programmed with a series of patient prostate motion trajectories exemplifying five distinct categories: stable prostate, slow drift, persistent excursion, transient excursion, and high frequency excursions. The phantom and fiducial were imaged using 140 kVp, 0.63 mAs per image at 1 Hz for a 60 s monitoring period. Both stereoscopic and monoscopic 3D localization accuracies were assessed by comparison to the ground-truth obtained from the Linac log file. Imaging dose was also assessed, using optically stimulated luminescence dosimeter inserts in the phantom. Results: Stereoscopic localization accuracy varied between 0.13 ± 0.05 and 0.33 ± 0.30 mm, depending on the motion trajectory. Monoscopic localization accuracy varied from 0.2 ± 0.1 to 1.1 ± 0.7 mm. The largest localization errors were typically observed in the left–right direction. There were significant differences in accuracy between the two monoscopic views, but which view was better varied from trajectory to trajectory. The imaging dose was measured to be between 2 and 15 μGy/mAs, depending on location in the phantom. Conclusions: The authors have demonstrated the first use of monoscopic localization for a room-mounted dual x-ray system. Three

  12. A concept of customer–provider relation monitoring system solution

    Directory of Open Access Journals (Sweden)

    Naděžda Chalupová

    2008-01-01

    Full Text Available The contribution deals with design of customer–provider relationship monitoring system solution with regard to needs of business managers and analytics and to possibilities of contemporaneous information and communication technologies.The attention is followed to targeted modelling, what brings possibilities of acquisition of bigger overview about things taking place in the relation. In consequence it describes the functionality of analytical systems producing these very strategically valuable models – to so-called business intelligence tools. Onward it deals with modern technologies conductive to above mentioned system implementation – with Ajax concept and with some XML applications: PMML for analytical models manipulation, XSLT for XML data transformations to various formats, SVG for representing pictures of statistical graphs etc. and MathML for description of mathematical formulas created in analytical systems.Following these basis it suggests technological solution of some parts of client–provider relationship watching and evaluating system and it discusses its potential advantages and problems, which can occur.

  13. A simulation study provided sample size guidance for differential item functioning (DIF) studies using short scales.

    Science.gov (United States)

    Scott, Neil W; Fayers, Peter M; Aaronson, Neil K; Bottomley, Andrew; de Graeff, Alexander; Groenvold, Mogens; Gundy, Chad; Koller, Michael; Petersen, Morten A; Sprangers, Mirjam A G

    2009-03-01

    Differential item functioning (DIF) analyses are increasingly used to evaluate health-related quality of life (HRQoL) instruments, which often include relatively short subscales. Computer simulations were used to explore how various factors including scale length affect analysis of DIF by ordinal logistic regression. Simulated data, representative of HRQoL scales with four-category items, were generated. The power and type I error rates of the DIF method were then investigated when, respectively, DIF was deliberately introduced and when no DIF was added. The sample size, scale length, floor effects (FEs) and significance level were varied. When there was no DIF, type I error rates were close to 5%. Detecting moderate uniform DIF in a two-item scale required a sample size of 300 per group for adequate (>80%) power. For longer scales, a sample size of 200 was adequate. Considerably larger sample sizes were required to detect nonuniform DIF, when there were extreme FEs or when a reduced type I error rate was required. The impact of the number of items in the scale was relatively small. Ordinal logistic regression successfully detects DIF for HRQoL instruments with short scales. Sample size guidelines are provided.

  14. 77 FR 7584 - Draft Guidance for Industry on Heparin for Drug and Medical Device Use; Monitoring Crude Heparin...

    Science.gov (United States)

    2012-02-13

    ... Management (HFA-305), Food and Drug Administration, 5630 Fishers Lane, rm. 1061, Rockville, MD 20852. See the... Quality.'' This draft guidance provides recommendations that will help API manufacturers, pharmaceutical... contaminant OSCS in heparin API manufactured in China. FDA is also concerned about the potential for...

  15. 77 FR 39959 - Draft Guidance To Implement Requirements for the Treatment of Air Quality Monitoring Data...

    Science.gov (United States)

    2012-07-06

    ... guidance: Please see the EPA's Web site at http://www.epa.gov/ttn/analysis/exevents.htm for additional... respond to specific questions or organize comments by referencing a Code of Federal Regulations (CFR) part... (72 FR at 13560). These documents are available online at http://www.epa.gov/ttn/analysis/exevents.htm...

  16. Providing guidance for genomics-based cancer treatment decisions: insights from stakeholder engagement for post-prostatectomy radiation therapy.

    Science.gov (United States)

    Abe, James; Lobo, Jennifer M; Trifiletti, Daniel M; Showalter, Timothy N

    2017-08-24

    aid program, based upon Markov modeling with individualized model inputs, to provide a patient-centered framework to support for genomic-based treatment decisions for cancer patients. The guidance provided by our stakeholders may be broadly applicable to the communication of genomic test results to patients in a patient-centered fashion that supports effective shared decision-making that represents a spectrum of personal factors such as age, medical comorbidities, and individual priorities and values.

  17. 77 FR 9945 - Draft Guidance for Industry on Providing Submissions in Electronic Format-Standardized Study Data...

    Science.gov (United States)

    2012-02-21

    ... current thinking on the submission of study data in a standard electronic format. The draft guidance... current thinking on submitting standardized study data in electronic format. It does not create or confer... Electronic Format--Standardized Study Data; Availability AGENCY: Food and Drug Administration, HHS. ACTION...

  18. Individualized guidance and telephone monitoring in a self-supervised home-based physiotherapeutic program in Parkinson

    Directory of Open Access Journals (Sweden)

    Ihana Thaís Guerra de Oliveira Gondim

    Full Text Available Abstract Introduction: Home therapeutic exercises have been a target of interest in the treatment of the Parkinson's disease (PD. The way that the physical therapist guides and monitors these exercises can impact the success of therapy. Objective: To evaluate the effects of individualized orientation and monitoring by telephone in a self-supervised home therapeutic exercise program on signs and symptoms of PD and quality of life (QoL. Methods: Single-blind randomized clinical trials with 28 people with PD (Hoehn and Yahr 1 to 3. Patients were randomized into two groups: experimental and control. The experimental group had a meeting with individualized guidance about physiotherapy exercises present in a manual, received the manual to guide their activities at home and obtained subsequent weekly monitoring by telephone. The control group received the usual cares by the service. Both were orientated to carry out exercises three times a week during 12 weeks. Was evaluated: (1 activities of daily living (ADL and motor examination sections of the Unified Parkinson's Disease Rating Scale (UPDRS and QoL by the Parkinson Disease Questionnaire 39 (PDQ-39. The analysis between groups was performed by the Mann-Whitney test and intragroup through the Wilcoxon (p < 0.05. Results: Significant improvement in ADL (p= 0.001 and motor examination (p= 0.0008 of the UPDRS, PDQ-39 total (p = 0.027 and dimensions mobility (p = 0.027, emotional well-being (p= 0.021 and bodily discomfort (p = 0.027 in the experimental group compared to the control group. Conclusion: The individualized guidance and weekly monitoring by telephone in a self-supervised home therapeutic exercises program promoted positive effects on ADL, motor examination and QoL of people in early stages of PD.

  19. No Ifs, No Butts: Compliance with Smoking Cessation in Secondary Care Guidance (NICE PH48) by Providers of Cancer Therapies (Radiotherapy and Chemotherapy) in the UK

    Science.gov (United States)

    Hutton, Daniel; Gee, Ivan; McGee, Ciara E.; Mellor, Rebecca

    2016-01-01

    Background: Legislation preventing smoking in public places was introduced in England in July 2007. Since then, smoke-free policies have been extended to the majority of hospitals including those providing cancer therapies. Whilst studies have been conducted on the impact and effectiveness of hospital smoke-free policy in the UK and other countries, there have not been any studies with a focus on cancer care providers. Cancer patients are a priority group for smoking cessation and support and this study aimed to examine implementation of the National Institute Clinical Excellence (NICE) guidance (PH48) in acute cancer care trusts in the UK. Methods: Participants were recruited from UK radiotherapy and chemotherapy departments (total 80 sites, 65 organisations) and asked to complete a 15 min online questionnaire exploring the implementation of NICE guidance at their hospital site. Results: Considerable variability in implementation of the NICE guidance was observed. A total of 79.1% trusts were smoke-free in theory; however, only 18.6% were described as smoke-free in practice. Areas of improvement were identified in information and support for patients and staff including in Nicotine Replacement Therapy (NRT) provision, staff training and clarity on e-cigarette policies. Conclusions: While some trusts have effective smoke-free policies and provide valuable cessation support services for patients, improvements are required to ensure that all sites fully adopt the NICE guidance. PMID:27983709

  20. No Ifs, No Butts: Compliance with Smoking Cessation in Secondary Care Guidance (NICE PH48 by Providers of Cancer Therapies (Radiotherapy and Chemotherapy in the UK

    Directory of Open Access Journals (Sweden)

    Daniel Hutton

    2016-12-01

    Full Text Available Background: Legislation preventing smoking in public places was introduced in England in July 2007. Since then, smoke-free policies have been extended to the majority of hospitals including those providing cancer therapies. Whilst studies have been conducted on the impact and effectiveness of hospital smoke-free policy in the UK and other countries, there have not been any studies with a focus on cancer care providers. Cancer patients are a priority group for smoking cessation and support and this study aimed to examine implementation of the National Institute Clinical Excellence (NICE guidance (PH48 in acute cancer care trusts in the UK. Methods: Participants were recruited from UK radiotherapy and chemotherapy departments (total 80 sites, 65 organisations and asked to complete a 15 min online questionnaire exploring the implementation of NICE guidance at their hospital site. Results: Considerable variability in implementation of the NICE guidance was observed. A total of 79.1% trusts were smoke-free in theory; however, only 18.6% were described as smoke-free in practice. Areas of improvement were identified in information and support for patients and staff including in Nicotine Replacement Therapy (NRT provision, staff training and clarity on e-cigarette policies. Conclusions: While some trusts have effective smoke-free policies and provide valuable cessation support services for patients, improvements are required to ensure that all sites fully adopt the NICE guidance.

  1. Update: Interim Guidance for Health Care Providers Caring for Women of Reproductive Age with Possible Zika Virus Exposure--United States, 2016.

    Science.gov (United States)

    Petersen, Emily E; Polen, Kara N D; Meaney-Delman, Dana; Ellington, Sascha R; Oduyebo, Titilope; Cohn, Amanda; Oster, Alexandra M; Russell, Kate; Kawwass, Jennifer F; Karwowski, Mateusz P; Powers, Ann M; Bertolli, Jeanne; Brooks, John T; Kissin, Dmitry; Villanueva, Julie; Muñoz-Jordan, Jorge; Kuehnert, Matthew; Olson, Christine K; Honein, Margaret A; Rivera, Maria; Jamieson, Denise J; Rasmussen, Sonja A

    2016-04-01

    CDC has updated its interim guidance for U.S. health care providers caring for women of reproductive age with possible Zika virus exposure to include recommendations on counseling women and men with possible Zika virus exposure who are interested in conceiving. This guidance is based on limited available data on persistence of Zika virus RNA in blood and semen. Women who have Zika virus disease should wait at least 8 weeks after symptom onset to attempt conception, and men with Zika virus disease should wait at least 6 months after symptom onset to attempt conception. Women and men with possible exposure to Zika virus but without clinical illness consistent with Zika virus disease should wait at least 8 weeks after exposure to attempt conception. Possible exposure to Zika virus is defined as travel to or residence in an area of active Zika virus transmission ( http://www.cdc.gov/zika/geo/active-countries.html), or sex (vaginal intercourse, anal intercourse, or fellatio) without a condom with a man who traveled to or resided in an area of active transmission. Women and men who reside in areas of active Zika virus transmission should talk with their health care provider about attempting conception. This guidance also provides updated recommendations on testing of pregnant women with possible Zika virus exposure. These recommendations will be updated when additional data become available.

  2. Minimally invasive ultrasound thermal therapy with MR thermal monitoring and guidance

    Science.gov (United States)

    Diederich, Chris J.; Stafford, R. Jason; Price, Roger E.; Nau, William H.; Tyreus, Per Daniel; Rivera, Belinda; Schomer, Donald; Olsson, Lars; Hazle, John D.

    2001-06-01

    In this study both transurethral and interstitial ultrasound thermal therapy were applied to thermally coagulate targeted portions of the canine prostate or brain and implanted TVT tumors while using MRI-based thermal mapping techniques to monitor the therapy. MRI was also used for target definition, positioning of the applicator, and evaluation of target viability post-therapy. The complex phase-difference mapping technique using an iGE-EPI sequence with lipid suppression was used for determining temperature elevations within the in vivo prostate or brain and surrounding structures. Calculated temperature distributions, thermal dose exposures, T2-wieghted & T1-contrast enhanced images, gross inspection, and histology of sectioned prostates and brains were in good agreement with each other in defining destroyed tissue zones. Interstitial and transurethral ultrasound applicators produce directed zones of thermal coagulation within targeted tissue and implanted tumor, which can be accurately monitored and evaluated by MRI.

  3. Monitoring the Internet Postings of Junior High School Students with the Aim of Improving Student Guidance : Study on Internet Use by Adolescent Girls

    OpenAIRE

    加藤, 千枝; 堀田, 香織

    2012-01-01

    In this research, the author monitored the content of Internet postings by students at two public junior high schools, and exchanged information regarding the content of the postings with their teachers on a regular basis. This paper is a report on the practice of monitoring whereby the content obtained from this information exchange was used by teachers for student understanding and student guidance.Specifically, the paper introduces two students as case studies and presents the case outline...

  4. Guidance on home blood pressure monitoring: A statement of the HOPE Asia Network.

    Science.gov (United States)

    Kario, Kazuomi; Park, Sungha; Buranakitjaroen, Peera; Chia, Yook-Chin; Chen, Chen-Huan; Divinagracia, Romeo; Hoshide, Satoshi; Shin, Jinho; Siddique, Saulat; Sison, Jorge; Soenarta, Arieska Ann; Sogunuru, Guru Prasad; Tay, Jam Chin; Turana, Yuda; Wong, Lawrence; Zhang, Yuqing; Wang, Ji-Guang

    2018-02-16

    Hypertension is an important modifiable cardiovascular risk factor and a leading cause of death throughout Asia. Effective prevention and control of hypertension in the region remain a significant challenge despite the availability of several regional and international guidelines. Out-of-office measurement of blood pressure (BP), including home BP monitoring (HBPM), is an important hypertension management tool. Home BP is better than office BP for predicting cardiovascular risk and HBPM should be considered for all patients with office BP ≥ 130/85 mm Hg. It is important that HBPM is undertaken using a validated device and patients are educated about how to perform HBPM correctly. During antihypertensive therapy, monitoring of home BP control and variability is essential, especially in the morning. This is because HBPM can facilitate the choice of individualized optimal therapy. The evidence and practice points in this document are based on the Hypertension Cardiovascular Outcome Prevention and Evidence (HOPE) Asia Network expert panel consensus recommendations for HBPM in Asia. ©2018 Wiley Periodicals, Inc.

  5. Vison guidance of a laser profiler for monitoring refractory lining wear in steel mills

    Science.gov (United States)

    Ailisto, Heikki J.; Mitikka, Risto S.; Moring, Ilkka; Jokinen, Hannu

    1995-09-01

    A laser rangefinder-based optical coordinate measurement system used for monitoring refractory lining wear in steel mills has been equipped with a vision system to improve its operative and performance characteristics. The 3D shape of the refractory lining is measured after renewal at the beginning of a campaign and these data are stored as a reference. During the campaign the lining is measured and the results are compared against the reference data in order to minimize risks and optimize lining life. To make the results measured at different times comparable, they must be accurately and reliably transformed to the same coordinate system. This makes the coordinate system setup phase critical for the success of the lining wear monitoring. Other important aspects are the amount of expensive process time taken up by the measurements and work safety aspects. The experimental vision system has been tesetd for automating the corrdinate system setup phase, and improved repeatability and faster operation compared with manual setup was achieved. Tentative tests at a steel mill proved promising, and further development of the vision system is going on.

  6. Federal Guidance for Radiation Protection

    Science.gov (United States)

    EPA produces federal guidance technical reports, which standardize dose and risk assessment and issues radiation protection guidance to federal agencies. This page provides links to federal guidance policy recommendations and technical reports.

  7. MR imaging guidance and monitoring of focal thermotherapies. A review; Steuerung und Monitoring von fokalen Thermotherapien mit der Magnetresonanztomographie. Ein Ueberblick

    Energy Technology Data Exchange (ETDEWEB)

    Mueller-Lisse, U.G. [Muenchen Univ. (Germany). Inst. fuer Radiologische Diagnostik am Klinikum Grosshadern]|[California Univ., San Francisco, CA (United States). Dept. of Radiology; Heuck, A.F. [Muenchen Univ. (Germany). Inst. fuer Radiologische Diagnostik am Klinikum Grosshadern

    1998-03-01

    Minimally invasive thermotherapies for focal tissue destruction on the basis of laser-, microwave-, focused ultrasound-, or cryogeninduced changes of tissue temperature represent an alternative to surgical tissue ablation, particularly in the treatment of tumors. The thermotherapy modalities listed necessitate indirect guidance and monitoring, since they often do not lend themselves to immediate visual control. In the brain, in head and neck tumors, in the liver, and in the prostate, MRI reliably and accurately delineates both the positions of interstitial thermotherapy applicators and - in contrast-enhanced, T1-weighted images - the perfusion defects in tissue necrosis induced by thermotherapy. The transfer of results of in-vitro and in-vivo model studies to assess interstitial temperature and lesion development during thermotherapy to the actual treatment of patients, however, is still in an initial phase. Further development of both rapid MRI sequences and MRI scanners suited for interventions will show how far treatment systems and guidance systems can be adapted to one another. (orig.) [Deutsch] Minimal-invasive Thermotherapien zur oertlich begrenzten Gewebedestruktion auf der Basis von Laser-, Mikrowellen-, Ultraschall- oder Kryogen-induzierten Veraenderungen der Gewebetemperatur koennen insbesondere bei der Behandlung tumoroeser Erkrankungen eine Alternative zur chirurgischen Resektion darstellen. Die genannten Therapieverfahren beduerfen der indirekten Steuerung durch bildgebende Verfahren, da sie sich meist der unmittelbaren Sicht entziehen. Mit der MRT kann sowohl die Position geeigneter Thermoapplikatoren als auch - durch kontrastverstaerkte, T1-gewichteten Aufnahmen - der Perfusionsausfall in thermisch induzierten Gewebsnekrosen zuverlaessig und genau dargestellt werden. Entsprechende Ergebnisse liegen fuer MR-gesteuerte Thermotherapien im Bereich des Gehirns, der Kopf-Halsregion, der Leber und der Prostata vor. Die Ergebnisse von In-vitro- und In

  8. Hardware Implementation of a Spline-Based Genetic Algorithm for Embedded Stereo Vision Sensor Providing Real-Time Visual Guidance to the Visually Impaired

    Directory of Open Access Journals (Sweden)

    James K. Archibald

    2008-04-01

    Full Text Available Many image and signal processing techniques have been applied to medical and health care applications in recent years. In this paper, we present a robust signal processing approach that can be used to solve the correspondence problem for an embedded stereo vision sensor to provide real-time visual guidance to the visually impaired. This approach is based on our new one-dimensional (1D spline-based genetic algorithm to match signals. The algorithm processes image data lines as 1D signals to generate a dense disparity map, from which 3D information can be extracted. With recent advances in electronics technology, this 1D signal matching technique can be implemented and executed in parallel in hardware such as field-programmable gate arrays (FPGAs to provide real-time feedback about the environment to the user. In order to complement (not replace traditional aids for the visually impaired such as canes and Seeing Eyes dogs, vision systems that provide guidance to the visually impaired must be affordable, easy to use, compact, and free from attributes that are awkward or embarrassing to the user. “Seeing Eye Glasses,” an embedded stereo vision system utilizing our new algorithm, meets all these requirements.

  9. Hardware Implementation of a Spline-Based Genetic Algorithm for Embedded Stereo Vision Sensor Providing Real-Time Visual Guidance to the Visually Impaired

    Science.gov (United States)

    Lee, Dah-Jye; Anderson, Jonathan D.; Archibald, James K.

    2008-12-01

    Many image and signal processing techniques have been applied to medical and health care applications in recent years. In this paper, we present a robust signal processing approach that can be used to solve the correspondence problem for an embedded stereo vision sensor to provide real-time visual guidance to the visually impaired. This approach is based on our new one-dimensional (1D) spline-based genetic algorithm to match signals. The algorithm processes image data lines as 1D signals to generate a dense disparity map, from which 3D information can be extracted. With recent advances in electronics technology, this 1D signal matching technique can be implemented and executed in parallel in hardware such as field-programmable gate arrays (FPGAs) to provide real-time feedback about the environment to the user. In order to complement (not replace) traditional aids for the visually impaired such as canes and Seeing Eyes dogs, vision systems that provide guidance to the visually impaired must be affordable, easy to use, compact, and free from attributes that are awkward or embarrassing to the user. "Seeing Eye Glasses," an embedded stereo vision system utilizing our new algorithm, meets all these requirements.

  10. Anticipatory guidance for children and adolescents with Fetal Alcohol Spectrum Disorder (FASD): practice points for primary health care providers.

    Science.gov (United States)

    Hanlon-Dearman, Ana; Green, Courtney R; Andrew, Gail; LeBlanc, Nicole; Cook, Jocelynn L

    2015-01-01

    Fetal Alcohol Spectrum Disorder (FASD) is an umbrella term that describes the range of effects that can occur in an individual who was prenatally exposed to alcohol and includes an array of complex neurodevelopmental and physical findings. To give primary healthcare providers (PHCP) evidence-based recommendations for supporting and managing the symptoms of FASD after patients have received a diagnosis. MethodsPrimary health recommendations for the management of children and adolescents with FASD were developed based on expert clinical judgment and supported by evidence-based research, where appropriate. The format was adapted from other health supervision practice guidelines as developed by the American Academy of Pediatrics. Clinical practice "Points" for the PHCP are highlighted. A reference table of anticipatory recommendations by age is presented. In most cases, the initial screening and referral for diagnosis will be made by the PHCP, and they will be responsible for ongoing management. It is anticipated that these recommendations will provide the PHCP with evidence to support the longitudinal health care of children and adolescents with FASD and their families as they transition throughout all developmental stages. There is a pressing need for the involvement of PHCP in the active care of children and adolescents with FASD and their families over the lifespan. PHCP are trained in screening, prevention, and management of health needs, and are in the position to coordinate sub-specialty referrals as needed. Engaging PHCP will provide a truly integrated care system for individuals with FASD and their families.

  11. Spiritual care competence for contemporary nursing practice: A quantitative exploration of the guidance provided by fundamental nursing textbooks.

    Science.gov (United States)

    Timmins, Fiona; Neill, Freda; Murphy, Maryanne; Begley, Thelma; Sheaf, Greg

    2015-11-01

    Spirituality is receiving unprecedented attention in the nursing literature. Both the volume and scope of literature on the topic is expanding, and it is clear that this topic is of interest to nurses. There is consensus that the spiritual required by clients receiving health ought to be an integrated effort across the health care team. Although undergraduate nurses receive some education on the topic, this is ad hoc and inconsistent across universities. Textbooks are clearly a key resource in this area however the extent to which they form a comprehensive guide for nursing students and nurses is unclear. This study provides a hitherto unperformed analysis of core nursing textbooks to ascertain spirituality related content. 543 books were examined and this provides a range of useful information about inclusions and omissions in this field. Findings revealed that spirituality is not strongly portrayed as a component of holistic care and specific direction for the provision of spiritual care is lacking. Fundamental textbooks used by nurses and nursing students ought to inform and guide integrated spiritual care and reflect a more holistic approach to nursing care. The religious and/or spiritual needs of an increasingly diverse community need to be taken seriously within scholarly texts so that this commitment to individual clients' needs can be mirrored in practice. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Quality in career guidance: The Danish case

    DEFF Research Database (Denmark)

    Plant, Peter

    2011-01-01

    Quality assurance systems are introduced in career guidance to monitor, control and develop guidance interventions. The Danish case represents at centrally driven, top-down approach......Quality assurance systems are introduced in career guidance to monitor, control and develop guidance interventions. The Danish case represents at centrally driven, top-down approach...

  13. Computerized Childbirth Monitoring Tools for Health Care Providers Managing Labor: A Scoping Review.

    Science.gov (United States)

    Balikuddembe, Michael S; Tumwesigye, Nazarius M; Wakholi, Peter K; Tylleskär, Thorkild

    2017-06-15

    Proper monitoring of labor and childbirth prevents many pregnancy-related complications. However, monitoring is still poor in many places partly due to the usability concerns of support tools such as the partograph. In 2011, the World Health Organization (WHO) called for the development and evaluation of context-adaptable electronic health solutions to health challenges. Computerized tools have penetrated many areas of health care, but their influence in supporting health staff with childbirth seems limited. The objective of this scoping review was to determine the scope and trends of research on computerized labor monitoring tools that could be used by health care providers in childbirth management. We used key terms to search the Web for eligible peer-reviewed and gray literature. Eligibility criteria were a computerized labor monitoring tool for maternity service providers and dated 2006 to mid-2016. Retrieved papers were screened to eliminate ineligible papers, and consensus was reached on the papers included in the final analysis. We started with about 380,000 papers, of which 14 papers qualified for the final analysis. Most tools were at the design and implementation stages of development. Three papers addressed post-implementation evaluations of two tools. No documentation on clinical outcome studies was retrieved. The parameters targeted with the tools varied, but they included fetal heart (10 of 11 tools), labor progress (8 of 11), and maternal status (7 of 11). Most tools were designed for use in personal computers in low-resource settings and could be customized for different user needs. Research on computerized labor monitoring tools is inadequate. Compared with other labor parameters, there was preponderance to fetal heart monitoring and hardly any summative evaluation of the available tools. More research, including clinical outcomes evaluation of computerized childbirth monitoring tools, is needed.

  14. Guidance Protocol: Application of Nucleic Acid-Based Tools for Monitoring Monitored Natural Attenuation (MNA), Biostimulation, and Bioaugmentation at Chlorinated Solvent Sites

    Science.gov (United States)

    2011-02-01

    MONITORING MONITORED NATURAL ATTENUATION (MNA), BIOSTIMULATION AND BIOAUGMENTATION AT CHLORINATED SOLVENT SITES ESTCP Project ER0518 NAVFAC ESC...of Nucleic Acid-Based Tools for Monitoring Monitored Natural Attenuation (MNA), Biostimulation, and Bioaugmentation at Chlorinated Solvent Sites 5a...Monitoring Monitored Natural Attenuation (MNA), Biostimulation, and Bioaugmentation at Chlorinated Solvent Sites January 2011 ESTCP ER

  15. The nursing implications of routine provider-initiated HIV testing and counselling in sub-Saharan Africa: a critical review of new policy guidance from WHO/UNAIDS.

    Science.gov (United States)

    Evans, Catrin; Ndirangu, Eunice

    2009-05-01

    In 2007 WHO/UNAIDS issued new HIV testing guidelines recommending 'provider-initiated HIV testing and counselling' (PITC). In contrast to existing 'voluntary counselling and testing' guidelines (whereby individuals self refer for testing), the PITC guidance recommends that, in countries with generalised epidemics, all patients are routinely offered an HIV test during clinical encounters. In sub-Saharan Africa, PITC aims to dramatically increase HIV testing rates so that PITC becomes a vehicle to increase access to HIV prevention and care. Nurses in this region work on the frontlines of HIV testing but have been neglected in related policy development. To provide an overview of the PITC policy guidance and to critically consider its implications for the nursing profession in sub-Saharan Africa. Policy documents and published and unpublished research were identified from organisational websites, electronic databases and conference proceedings. PITC has generated widespread debate about whether it is the right approach in a context of HIV-related stigma and lack of human/material resources. Key concerns are whether/how informed consent, privacy and confidentiality will be upheld in overstretched health care settings, and whether appropriate post-test counselling, treatment and support can be provided. Limited available evidence suggests that health systems factors and organisational/professional culture may create obstacles to effective PITC implementation. Specific findings are that: PITC greatly increases nurses' workload and work-related stress. Nurses are generally positive about PITC, but express the need for more training and managerial support. Health system constraints (lack of staff, lack of space) mean that nurses do not always have time to provide adequate counselling. A hierarchical and didactic nursing culture affects counselling quality and the boundaries between voluntary informed consent and coercion can become rather blurred. Nurses are particularly

  16. U.S. Geological Survey shrub/grass products provide new approach to shrubland monitoring

    Science.gov (United States)

    Young, Steven M.

    2017-12-11

    In the Western United States, shrubland ecosystems provide vital ecological, hydrological, biological, agricultural, and recreational services. However, disturbances such as livestock grazing, exotic species invasion, conversion to agriculture, climate change, urban expansion, and energy development are altering these ecosystems.Improving our understanding of how shrublands are distributed, where they are changing, the extent of the historical change, and likely future change directions is critical for successful management of these ecosystems. Remote-sensing technologies provide the most likely data source for large-area monitoring of ecosystem disturbance—both near-real time and historically. A monitoring framework supported by remote-sensing data can offer efficient and accurate analysis of change across a range of spatial and temporal scales.The U.S. Geological Survey has been working to develop new remote-sensing data, tools, and products to characterize and monitor these changing shrubland landscapes. Nine individual map products (components) have been developed that quantify the percent of shrub, sagebrush, big sagebrush, herbaceous, annual herbaceous, litter, bare ground, shrub height, and sagebrush height at 1-percent intervals in each 30-meter grid cell. These component products are designed to be combined and customized to widely support different applications in rangeland monitoring, analysis of wildlife habitat, resource inventory, adaptive management, and environmental review.

  17. French citizens monitoring ordinary birds provide tools for conservation and ecological sciences

    Science.gov (United States)

    Jiguet, Frédéric; Devictor, Vincent; Julliard, Romain; Couvet, Denis

    2012-10-01

    Volunteer-based standardized monitoring of birds has been widely implemented in Europe and North America. In France, a breeding bird survey is running since 1989 and offers keen birdwatchers to count spring birds annually during 5 min exactly on 10 fix points within a randomly selected square. The first goal of such breeding bird surveys is to measure temporal trends in order to detect possible species declines. Combining annual indices of species sharing ecological affinities or a protected/red list status further provides biodiversity indicators for policy makers. Because the sampling effort is similar among sites, and because the initial selection of monitored sites is random, the temporal trends can be considered representative of national trends, and spatial comparisons of the obtained metrics are possible. Species abundance, community richness but also community specialization and average trophic level can be estimated for each site and each year and further related to the wide range of habitat and landscape characteristics and to agricultural or forestry practices. The large number of sites allows overcoming the opposition between adaptive and passive monitoring, making such schemes fitted to adaptive monitoring. This provides opportunities to determine which type of management or practices favour biodiversity. The comparison of population fate or community dynamics across a wide range of climates and temperatures, e.g. from southern to northern Europe, revealed how European birds are already affected by climate change. Bird communities are shifting northwards, but at a slower rate than temperatures, while bird populations have larger growth rates away from their hot thermal limit. Finally, such large-scale long-term monitoring data on a complete taxonomic group (Aves) is original and offers the opportunity to compare different measures of biological diversity, such as taxonomic, phylogenetic and functional diversity. Such a citizen science scheme is an

  18. A Systematic Review of End-of-Life Care Communication Skills Training for Generalist Palliative Care Providers: Research Quality and Reporting Guidance.

    Science.gov (United States)

    Brighton, Lisa Jane; Koffman, Jonathan; Hawkins, Amy; McDonald, Christine; O'Brien, Suzanne; Robinson, Vicky; Khan, Shaheen A; George, Rob; Higginson, Irene J; Selman, Lucy Ellen

    2017-09-01

    End-of-life care (EoLC) communication skills training for generalist palliative care providers is recommended in policy guidance globally. Although many training programs now exist, there has been no comprehensive evidence synthesis to inform future training delivery and evaluation. To identify and appraise how EoLC communication skills training interventions for generalist palliative care providers are developed, delivered, evaluated, and reported. Systematic review. Ten electronic databases (inception to December 2015) and five relevant journals (January 2004 to December 2015) were searched. Studies testing the effectiveness of EoLC communication skills training for generalists were included. Two independent authors assessed study quality. Descriptive statistics and narrative synthesis are used to summarize the findings. From 11,441 unique records, 170 reports were identified (157 published, 13 unpublished), representing 160 evaluation studies of 153 training interventions. Of published papers, eight were of low quality, 108 medium, and 41 high. Few interventions were developed with service user involvement (n = 7), and most were taught using a mixture of didactics (n = 123), reflection and discussion (n = 105), and role play (n = 86). Evaluation designs were weak: skills training interventions in the literature, evidence is limited by poor reporting and weak methodology. Based on our findings, we present a CONSORT statement supplement to improve future reporting and encourage more rigorous testing. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  19. Hurricane Season Public Health Preparedness, Response, and Recovery Guidance for Health Care Providers, Response and Recovery Workers, and Affected Communities - CDC, 2017.

    Science.gov (United States)

    2017-09-22

    CDC and the Agency for Toxic Substances and Disease Registry (ATSDR) have guidance and technical materials available in both English and Spanish to help communities prepare for hurricanes and floods (Table 1). To help protect the health and safety of the public, responders, and clean-up workers during response and recovery operations from hurricanes and floods, CDC and ATSDR have developed public health guidance and other resources; many are available in both English and Spanish (Table 2).

  20. Analysis of the astray/robo2 zebrafish mutant reveals that degenerating tracts do not provide strong guidance cues for regenerating optic axons

    Science.gov (United States)

    Wyatt, Cameron; Ebert, Anselm; Reimer, Michell M.; Rasband, Kendall; Hardy, Melissa; Chien, Chi-Bin; Becker, Thomas; Becker, Catherina G.

    2010-01-01

    During formation of the optic projection in astray/robo2 mutant zebrafish, optic axons exhibit rostro-caudal pathfinding errors, ectopic midline crossing and increased terminal arbor size. Here we show that these errors persist into adulthood, even when robo2 function is conditionally reduced only during initial formation of the optic projection. Adult errors include massive ectopic optic tracts in the telencephalon. During optic nerve regeneration in astray/robo2 animals, these tracts are not re-populated and ectopic midline crossing is reduced compared to unlesioned mutants. This is despite a comparable macrophage/microglial response and upregulation of contactin1a in oligodendrocytes of entopic and ectopic tracts. However, other errors, such as expanded termination areas and ectopic growth into the tectum, were frequently re-committed by regenerating optic axons. Retinal ganglion cells with regenerating axons re-express robo2 and expression of slit ligands is maintained in some areas of the adult optic pathway. However, slit expression is reduced rostral and caudal to the chiasm, compared to development and ubiquitous overexpression of Slit2 did not elicit major pathfinding phenotypes. This shows that (1) there is not an efficient correction mechanism for large-scale pathfinding errors of optic axons during development; (2) degenerating tracts do not provide a strong guidance cue for regenerating optic axons in the adult CNS, unlike the PNS; and (3) robo2 is less important for pathfinding of optic axons during regeneration than during development. PMID:20943924

  1. Robotic Anatrophic Nephrolithotomy Utilizing Near-infrared Fluorescence Image-guidance: Idea, Development, Exploration, Assessment, and Long-term Monitoring (IDEAL) Stage 0 Animal Model Study.

    Science.gov (United States)

    Sood, Akshay; Hemal, Ashok K; Assimos, Dean G; Peabody, James O; Menon, Mani; Ghani, Khurshid R

    2016-08-01

    To test the feasibility of robotic anatrophic nephrolithotomy (RANL) using near-infrared fluorescence (NIRF) image-guidance for treating staghorn stones, in an in vivo stone surgery model. We developed a novel technique of RANL in a preclinical setting following guidelines on safe surgical innovation from the Idea, Development, Exploration, Assessment, Long-term monitoring (IDEAL) collaborative. We performed 2 RANL procedures on 2 live Yorkshire porcine females (IDEAL stage 0 study). The robot was docked in the flank position and a mini-GelPOINT was placed periumbilically as an assistant port. A model staghorn "stone" was created in vivo by injecting low-viscosity DenMat precision material into the renal pelvis. NIRF image-guidance, following clamping of the posterior renal artery, was used to determine if an anatrophic plane could be identified. One procedure was assessed under cold ischemia, with ice-slush injected onto the renal surface via the mini-GelPOINT. Both porcine subjects underwent RANL successfully. Replica staghorn models could be created reliably (mean size 5.1 cm; solidification time 2-3 minutes). NIRF image-guidance afforded clear vascular demarcation for precise scoring of an anatrophic plane in both kidneys. The staghorn models were removed in toto through the anatrophic incision in both subjects. Mean blood loss was 160 cc. Mean console and ischemia times were 114 minutes and 34.5 minutes, respectively; ice-slush hypothermia led to a renal surface temperature of 15.4°C. In this IDEAL stage 0 preclinical study, we demonstrated that NIRF image-guidance is able to accurately identify the renal avascular plane, thus permitting an anatrophic approach for robotic excision of staghorn stones. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Guidelines for the use of biological monitors in air pollution control (plants). Pt. 1. Methodological guidance for the drawing-up of biomonitoring guidelines (plants)

    Energy Technology Data Exchange (ETDEWEB)

    Zimmermann, R.D. [Buero fuer Konzeptionelle Bioindikation, Jockgrim (Germany); Wagner, G. [Universitaet des Saarlandes, Saarbruecken (Germany). Inst. fuer Biogeographie; Finck, M.

    2000-04-01

    The main objective of this study is to encourage and promote further development of the methodological basis for a broader and more effective use of biological methods for monitoring the effects of air pollution on plants. It is not intended here to explain or discuss general criteria for the design of environmental monitoring studies and principal statistical methods for dealing with heterogeneously distributed spatial phenomena in detail. A further objective of this study is to give general guidance on how to - select suitable bioindicators, - develop, optimise and validate specific guidelines for the use of these bioindicators, - plan, design and employ biomonitoring studies for different purposes, - develop case-specific study plans determining how to apply an appropriate bioindicator (method-specific guideline) to a given task, case and area, - adapt principles of quality assurance and quality control to biomonitoring studies, - increase the importance and reliability of results obtained by bioindicators with respect to administrative measures. (orig.)

  3. Monitoring chicken flock behaviour provides early warning of infection by human pathogen Campylobacter.

    Science.gov (United States)

    Colles, Frances M; Cain, Russell J; Nickson, Thomas; Smith, Adrian L; Roberts, Stephen J; Maiden, Martin C J; Lunn, Daniel; Dawkins, Marian Stamp

    2016-01-13

    Campylobacter is the commonest bacterial cause of gastrointestinal infection in humans, and chicken meat is the major source of infection throughout the world. Strict and expensive on-farm biosecurity measures have been largely unsuccessful in controlling infection and are hampered by the time needed to analyse faecal samples, with the result that Campylobacter status is often known only after a flock has been processed. Our data demonstrate an alternative approach that monitors the behaviour of live chickens with cameras and analyses the 'optical flow' patterns made by flock movements. Campylobacter-free chicken flocks have higher mean and lower kurtosis of optical flow than those testing positive for Campylobacter by microbiological methods. We show that by monitoring behaviour in this way, flocks likely to become positive can be identified within the first 7-10 days of life, much earlier than conventional on-farm microbiological methods. This early warning has the potential to lead to a more targeted approach to Campylobacter control and also provides new insights into possible sources of infection that could transform the control of this globally important food-borne pathogen. © 2016 The Authors.

  4. Monitoring consumer satisfaction with the clinical services provided to 'exceptional' children.

    Science.gov (United States)

    Sommers, P A; Nycz, G R

    1978-09-01

    Given recent federal and state legislation mandating all necessary services for children with handicapping conditions, it is incumbent upon the providers of health care services to demonstrate accountability for their services to children with special needs. A procedure to assess the satisfaction of parents and community-based case coordinators with clinical services provided to such children has been demonstrated. By focusing on specific service elements, it is possible to align optimum versus actual consumer satisfaction. Through an analysis of observed variance, the modification of documented weaknesses can decrease the difference between optimum and actual consumer satisfaction levels. This procedure will be continued on a bi-annual, longitudinal follow-up basis to monitor progress. The concept of consumer input into the provision of clinical services is relevant to other developments in the field of health care which place importance on administration accountability. Those health care providers who recognize the value of consumer input and allow for its incorporation into their service programs will be better able to adapt their systems to the emerging trend towards medical accountability. Self-ordered accountability is more meaningful, is easier to understand than government imposed regulations, and can be smoothly blended into an organization's goals and objectives.

  5. Laser Guidance Analysis Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility, which provides for real time, closed loop evaluation of semi-active laser guidance hardware, has and continues to be instrumental in the development...

  6. Fibromyalgia Symptom Reduction by Online Behavioral Self-monitoring, Longitudinal Single Subject Analysis and Automated Delivery of Individualized Guidance.

    Science.gov (United States)

    Collinge, William; Yarnold, Paul; Soltysik, Robert

    2013-09-01

    Fibromyalgia (FM) is a complex chronic pain condition that is difficult to treat. The prevailing approach is an integration of pharmacological, psycho-educational, and behavioral strategies. Information technology offers great potential for FM sufferers to systemically monitor symptoms as well as potential impacts of various management strategies. This study aimed to evaluate effects of a web-based, self-monitoring and symptom management system (SMARTLog) that analyzes personal self-monitoring data and delivers data-based feedback over time. Subjects were self-referred, anonymous, and recruited via publicity on FM advocacy websites. Standardized instruments assessed health status, self-efficacy, and locus of control at baseline and monthly during participation. Subjects were encouraged to complete the SMARTLog several times weekly. Within-subject, univariate, and multivariate analyses were used to derive classification trees for each user associating specific behavior variables with symptom levels over time. Moderate use (3 times weekly x 3 months) increased likelihood of clinically significant improvements in pain, memory, gastrointestinal problems, depression, fatigue, and concentration; heavy use (4.5 times weekly x five months) produced the above plus improvement in stiffness and sleep difficulties. Individualized, web-based behavioral self-monitoring with personally-tailored feedback can enable FM sufferers to significantly reduce symptom levels over time.

  7. Image Guidance

    Science.gov (United States)

    Guidance that explains the process for getting images approved in One EPA Web microsites and resource directories. includes an appendix that shows examples of what makes some images better than others, how some images convey meaning more than others

  8. Control and Guidance of Low-Cost Robots via Gesture Perception for Monitoring Activities in the Home

    Directory of Open Access Journals (Sweden)

    Angel D. Sempere

    2015-12-01

    Full Text Available This paper describes the development of a low-cost mini-robot that is controlled by visual gestures. The prototype allows a person with disabilities to perform visual inspections indoors and in domestic spaces. Such a device could be used as the operator's eyes obviating the need for him to move about. The robot is equipped with a motorised webcam that is also controlled by visual gestures. This camera is used to monitor tasks in the home using the mini-robot while the operator remains quiet and motionless. The prototype was evaluated through several experiments testing the ability to use the mini-robot’s kinematics and communication systems to make it follow certain paths. The mini-robot can be programmed with specific orders and can be tele-operated by means of 3D hand gestures to enable the operator to perform movements and monitor tasks from a distance.

  9. Control and Guidance of Low-Cost Robots via Gesture Perception for Monitoring Activities in the Home.

    Science.gov (United States)

    Sempere, Angel D; Serna-Leon, Arturo; Gil, Pablo; Puente, Santiago; Torres, Fernando

    2015-12-11

    This paper describes the development of a low-cost mini-robot that is controlled by visual gestures. The prototype allows a person with disabilities to perform visual inspections indoors and in domestic spaces. Such a device could be used as the operator's eyes obviating the need for him to move about. The robot is equipped with a motorised webcam that is also controlled by visual gestures. This camera is used to monitor tasks in the home using the mini-robot while the operator remains quiet and motionless. The prototype was evaluated through several experiments testing the ability to use the mini-robot's kinematics and communication systems to make it follow certain paths. The mini-robot can be programmed with specific orders and can be tele-operated by means of 3D hand gestures to enable the operator to perform movements and monitor tasks from a distance.

  10. Transoesophageal Doppler compared to central venous pressure for perioperative hemodynamic monitoring and fluid guidance in liver resection.

    Science.gov (United States)

    El Sharkawy, Osama A; Refaat, Emad K; Ibraheem, Abdel Elmoniem M; Mahdy, Wafiya R; Fayed, Nirmeen A; Mourad, Wesam S; Abd Elhafez, Hanaa S; Yassen, Khaled A

    2013-10-01

    Major hepatic resections may result in hemodynamic changes. Aim is to study transesophageal Doppler (TED) monitoring and fluid management in comparison to central venous pressure (CVP) monitoring. A follow-up comparative hospital based study. 59 consecutive cirrhotic patients (CHILD A) undergoing major hepatotomy. CVP monitoring only (CVP group), (n=30) and TED (Doppler group), (n=29) with CVP transduced but not available on the monitor. Exclusion criteria include contra-indication for Doppler probe insertion or bleeding tendency. An attempt to reduce CVP during the resection in both groups with colloid restriction, but crystalloids infusion of 6 ml/kg/h was allowed to replace insensible loss. Post-resection colloids infusion were CVP guided in CVP group (5-10 mmHg) and corrected flow time (FTc) aortic guided in Doppler group (>0.4 s) blood products given according to the laboratory data. Using the FTc to guide Hydroxyethyl starch 130/0.4 significantly decreased intake in TED versus CVP (1.03 [0.49] versus 1.74 [0.41] Liter; P 0.05). Cardiac index and stroke volume of TED increased post-resection compared to baseline, 3.0 (0.9) versus 3.6 (0.9) L/min/m(2), Pmonitoring was able to reduced colloids administration post-resection, lower morbidity and shorten hospital stay. TED consumed less time to insert and was also able to present significant hemodynamic changes. Advanced surgical techniques of resection play a key role in reducing blood loss despite CVP more than 5 cm H2O. TED fluid management protocols during resection need to be developed.

  11. First testing of an AUV mission planning and guidance system for water quality monitoring and fish behavior observation in net cage fish farming

    Directory of Open Access Journals (Sweden)

    D. Karimanzira

    2014-12-01

    Full Text Available Recently, underwater vehicles have become low cost, reliable and affordable platforms for performing various underwater tasks. While many aquaculture systems are closed with no harmful output, open net cage fish farms and land-based fish farms can discharge significant amounts of wastewater containing nutrients, chemicals, and pharmaceuticals that impact on the surrounding environment. Although aquaculture development has often occurred outside a regulatory framework, government oversight is increasingly common at both the seafood quality control level, and at baseline initiatives addressing the basic problem of pollution generated by culture operations, e.g. the European marine and maritime directives. This requires regular, sustainable and cost-effective monitoring of the water quality. Such monitoring needs devices to detect the water quality in a large sea area at different depths in real time. This paper presents a concept for a guidance system for a carrier (an autonomous underwater vehicle of such devices for the automated detection and analysis of water quality parameters.

  12. lmbali Guidance Project: Facilitating Development among Guidance ...

    African Journals Online (AJOL)

    A project to assist guidance educators in developing their skills, resources and confidence in providing a mental health service to the learners in their schools, was set up as part of a wider school-based reform initiative. The project was structured according to the principles of community psychology: community collaboration ...

  13. On-line MRI guidance for Radiotherapy

    OpenAIRE

    Crijns, S.P.M.

    2013-01-01

    Image-guided radiotherapy has the potential to increase success of treatment by decreasing uncertainties concerning tumour position and shape. MRI is the modality of choice when it comes to imaging for tumour delineation and characterisation, set-up correction, treatment plan adaptation, response monitoring and intra-fraction motion compensation. To boost the possibilities of image guidance by providing images with superior soft-tissue contrast during treatment, integrated diagnostic quality ...

  14. Radiofrequency ablation of small liver malignancies under magnetic resonance guidance: progress in targeting and preliminary observations with temperature monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Terraz, Sylvain; Cernicanu, Alexandru; Lepetit-Coiffe, Matthieu; Viallon, Magalie; Salomir, Rares; Becker, Christoph D. [University Hospitals of Geneva, Department of Radiology, Geneva 14 (Switzerland); Mentha, Gilles [University Hospitals of Geneva, Department of Visceral Surgery and Transplantation, Geneva (Switzerland)

    2010-04-15

    To evaluate the feasibility and effectiveness of magnetic resonance (MR)-guided radiofrequency (RF) ablation for small liver tumours with poor conspicuity on both contrast-enhanced ultrasonography (US) and computed tomography (CT), using fast navigation and temperature monitoring. Sixteen malignant liver nodules (long-axis diameter, 0.6-2.4 cm) were treated with multipolar RF ablation on a 1.5-T wide-bore MR system in ten patients. Targeting was performed interactively, using a fast steady-state free precession sequence. Real-time MR-based temperature mapping was performed, using gradient echo-echo planar imaging (GRE-EPI) and hardware filtering. MR-specific treatment data were recorded. The mean follow-up time was 19 {+-} 7 months. Correct placement of RF electrodes was obtained in all procedures (image update, <500 ms; mean targeting time, 21 {+-} 11 min). MR thermometry was available for 14 of 16 nodules (88%) with an accuracy of 1.6 C in a non-heated region. No correlation was found between the size of the lethal thermal dose and the ablation zone at follow-up imaging. The primary and secondary effectiveness rates were 100% and 91%, respectively. RF ablation of small liver tumours can be planned, targeted, monitored and controlled with MR imaging within acceptable procedure times. Temperature mapping is technically feasible, but the clinical benefit remains to be proven. (orig.)

  15. Resources for Guidance Program Improvement. Volume I.

    Science.gov (United States)

    Walz, Garry R., Comp.; And Others

    Designed for use by counselors, guidance directors, school administrators, school board members, and anyone interested in the improvement of school guidance programs, this resource book provides a collection of over 100 guidance program models and individual guidance practices. The format consists of references (bibliographic information with…

  16. Challenges to Providing a Successful Central Configuration Service to Support CERN’s New Controls Diagnostics and Monitoring System

    CERN Document Server

    Makonnen, Z; Zaharieva, Z

    2014-01-01

    The Controls Diagnostic and Monitoring service (DIAMON) provides monitoring and diagnostics tools to the operators in the CERN Control Centre. A recent reengineering presented the opportunity to restructure its data management and to integrate it with the central Controls Configuration Service (CCS). The CCS provides the Configuration Management for the Controls System for all accelerators at CERN. The new facility had to cater for the configuration management of all agents monitored by DIAMON, (>3000 computers of different types), provide deployment information, relations between metrics, and historical information. In addition, it had to be integrated into the operational CCS, while ensuring stability and data coherency. An important design decision was to largely reuse the existing infrastructure in the CCS and adapt the DIAMON data management to it e.g. by using the device/property model through a Virtual Devices framework to model the DIAMON agents. This article will show how these challenging requiremen...

  17. Monitoring Hazardous Fuels Treatments: Southeast Regional Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this document is to provide technical guidance on monitoring activities to refuge staff involved in planning and conducting hazardous fuel treatments....

  18. The Application of the DMC Strategy and Experience to Provide Additional Support to a European Global Monitoring System Programme

    Science.gov (United States)

    Cutter, M. A.; Giwa, S. C.; Graham, K. L.; Hodgson, D. J.; Mackin, S.; Sweeting, M. N.; Vanotti, M.; Regan, A.

    2008-08-01

    Surrey Satellite Technology Ltd has reviewed the ability of small satellites to provide additional capability to the presently defined Global Monitoring for Environment and Security (GMES) space segment, allowing the broadest set of user requirements to be met. User- focused services have been compared with the instruments defined for the currently proposed Sentinels. SSTL has developed the Disaster Monitoring Constellation (DMC) of small satellites at a very low cost, which provide land-focused data products in the visible wavebands with daily access capability. The study undertaken by SSTL for the European Space Agency analysed the DMC operational concept in a GMES context, reviewing a range of possible services with different payload configurations on small satellite platforms. One concept was selected and an appropriate payload definition derived. The chosen mission concept was based on the provision of near time operational oceanography information using a constellation of small satellites. The aim is to provide sea surface height, significant wave height and wind speed.

  19. A decision tree model to estimate the value of information provided by a groundwater quality monitoring network

    Science.gov (United States)

    Khader, A. I.; Rosenberg, D. E.; McKee, M.

    2013-05-01

    Groundwater contaminated with nitrate poses a serious health risk to infants when this contaminated water is used for culinary purposes. To avoid this health risk, people need to know whether their culinary water is contaminated or not. Therefore, there is a need to design an effective groundwater monitoring network, acquire information on groundwater conditions, and use acquired information to inform management options. These actions require time, money, and effort. This paper presents a method to estimate the value of information (VOI) provided by a groundwater quality monitoring network located in an aquifer whose water poses a spatially heterogeneous and uncertain health risk. A decision tree model describes the structure of the decision alternatives facing the decision-maker and the expected outcomes from these alternatives. The alternatives include (i) ignore the health risk of nitrate-contaminated water, (ii) switch to alternative water sources such as bottled water, or (iii) implement a previously designed groundwater quality monitoring network that takes into account uncertainties in aquifer properties, contaminant transport processes, and climate (Khader, 2012). The VOI is estimated as the difference between the expected costs of implementing the monitoring network and the lowest-cost uninformed alternative. We illustrate the method for the Eocene Aquifer, West Bank, Palestine, where methemoglobinemia (blue baby syndrome) is the main health problem associated with the principal contaminant nitrate. The expected cost of each alternative is estimated as the weighted sum of the costs and probabilities (likelihoods) associated with the uncertain outcomes resulting from the alternative. Uncertain outcomes include actual nitrate concentrations in the aquifer, concentrations reported by the monitoring system, whether people abide by manager recommendations to use/not use aquifer water, and whether people get sick from drinking contaminated water. Outcome costs

  20. A decision tree model to estimate the value of information provided by a groundwater quality monitoring network

    Directory of Open Access Journals (Sweden)

    A. I. Khader

    2013-05-01

    Full Text Available Groundwater contaminated with nitrate poses a serious health risk to infants when this contaminated water is used for culinary purposes. To avoid this health risk, people need to know whether their culinary water is contaminated or not. Therefore, there is a need to design an effective groundwater monitoring network, acquire information on groundwater conditions, and use acquired information to inform management options. These actions require time, money, and effort. This paper presents a method to estimate the value of information (VOI provided by a groundwater quality monitoring network located in an aquifer whose water poses a spatially heterogeneous and uncertain health risk. A decision tree model describes the structure of the decision alternatives facing the decision-maker and the expected outcomes from these alternatives. The alternatives include (i ignore the health risk of nitrate-contaminated water, (ii switch to alternative water sources such as bottled water, or (iii implement a previously designed groundwater quality monitoring network that takes into account uncertainties in aquifer properties, contaminant transport processes, and climate (Khader, 2012. The VOI is estimated as the difference between the expected costs of implementing the monitoring network and the lowest-cost uninformed alternative. We illustrate the method for the Eocene Aquifer, West Bank, Palestine, where methemoglobinemia (blue baby syndrome is the main health problem associated with the principal contaminant nitrate. The expected cost of each alternative is estimated as the weighted sum of the costs and probabilities (likelihoods associated with the uncertain outcomes resulting from the alternative. Uncertain outcomes include actual nitrate concentrations in the aquifer, concentrations reported by the monitoring system, whether people abide by manager recommendations to use/not use aquifer water, and whether people get sick from drinking contaminated water

  1. User-centered development and testing of a monitoring system that provides feedback regarding physical functioning to elderly people

    Directory of Open Access Journals (Sweden)

    Vermeulen J

    2013-08-01

    Full Text Available Joan Vermeulen,1 Jacques CL Neyens,1 Marieke D Spreeuwenberg,1 Erik van Rossum,1,2 Walther Sipers,3 Herbert Habets,3 David J Hewson,4 Luc P de Witte1,2 1School for Public Health and Primary Care (CAPHRI, Maastricht University, Maastricht, The Netherlands; 2Research Center for Technology in Care, Zuyd University of Applied Sciences, Heerlen, The Netherlands; 3Expertise Center for Elderly Care, Orbis Medical Center, Sittard, The Netherlands; 4Institute Charles Delaunay, Université de Technologie de Troyes, Troyes, France Purpose: To involve elderly people during the development of a mobile interface of a monitoring system that provides feedback to them regarding changes in physical functioning and to test the system in a pilot study. Methods and participants: The iterative user-centered development process consisted of the following phases: (1 selection of user representatives; (2 analysis of users and their context; (3 identification of user requirements; (4 development of the interface; and (5 evaluation of the interface in the lab. Subsequently, the monitoring and feedback system was tested in a pilot study by five patients who were recruited via a geriatric outpatient clinic. Participants used a bathroom scale to monitor weight and balance, and a mobile phone to monitor physical activity on a daily basis for six weeks. Personalized feedback was provided via the interface of the mobile phone. Usability was evaluated on a scale from 1 to 7 using a modified version of the Post-Study System Usability Questionnaire (PSSUQ; higher scores indicated better usability. Interviews were conducted to gain insight into the experiences of the participants with the system. Results: The developed interface uses colors, emoticons, and written and/or spoken text messages to provide daily feedback regarding (changes in weight, balance, and physical activity. The participants rated the usability of the monitoring and feedback system with a mean score of 5

  2. Safe, timely, convenient, and cost-effective: a single-center experience with bedside placement of enteral feeding tubes by midlevel providers using fluoroscopic guidance.

    Science.gov (United States)

    Hauschild, Tricia B; Fu, Katy Y; Hipwell, Randall C; Baraghoshi, Gabriele; Mone, Mary C; Nirula, Raminder; Kimball, Edward J; Barton, Richard G

    2012-12-01

    Enteral feeding tube placement has been performed by nurses, gastroenterologists using endoscopy, and interventional radiologists. We hypothesized that midlevel providers placed feeding tubes at bedside using fluoroscopy safely, rapidly, and cost-effectively. We retrospectively analyzed bedside feeding tube placement under fluoroscopy by trained nurse practitioners. We compared charges for this method with charges for placement by other practitioners. Nurse practitioners placed 632 feeding tubes in 462 patients. Three hundred seventy-nine placements took place in mechanically ventilated placements. Ninety-seven percent of tubes were positioned past the pylorus. The mean fluoroscopy time was 0.7 ± 1.2 minutes. The mean procedure time was 7.0 ± 5.1 minutes. All tubes were placed within 24 hours of the request. There were no complications. Institutional charges for tube placement were $149 for nurse practitioners, $226 for gastroenterologists, and $328 for interventional radiologists. The placement of feeding tubes under fluoroscopy by nurse practitioners is safe, timely, and cost-effective. Published by Elsevier Inc.

  3. Costing the distribution of insecticide-treated nets: a review of cost and cost-effectiveness studies to provide guidance on standardization of costing methodology.

    Science.gov (United States)

    Kolaczinski, Jan; Hanson, Kara

    2006-05-08

    Insecticide-treated nets (ITNs) are an effective and cost-effective means of malaria control. Scaling-up coverage of ITNs is challenging. It requires substantial resources and there are a number of strategies to choose from. Information on the cost of different strategies is still scarce. To guide the choice of a delivery strategy (or combination of strategies), reliable and standardized cost information for the different options is required. The electronic online database PubMed was used for a systematic search of the published English literature on costing and economic evaluations of ITN distribution programmes. The keywords used were: net, bednet, insecticide, treated, ITN, cost, effectiveness, economic and evaluation. Identified papers were analysed to determine and evaluate the costing methods used. Methods were judged against existing standards of cost analysis to arrive at proposed standards for undertaking and presenting cost analyses. Cost estimates were often not readily comparable or could not be adjusted to a different context. This resulted from the wide range of methods applied and measures of output chosen. Most common shortcomings were the omission of certain costs and failure to adjust financial costs to generate economic costs. Generalisability was hampered by authors not reporting quantities and prices of resources separately and not examining the sensitivity of their results to variations in underlying assumptions. The observed shortcomings have arisen despite the abundance of literature and guidelines on costing of health care interventions. This paper provides ITN specific recommendations in the hope that these will help to standardize future cost estimates.

  4. Effectiveness of a reduced dose of efavirenz plus 2 NRTIs as maintenance antiretroviral therapy with the guidance of therapeutic drug monitoring.

    Science.gov (United States)

    Yang, Shang-Ping; Liu, Wen-Chun; Lee, Kuan-Yeh; Wu, Bing-Ru; Su, Yi-Ching; Wu, Pei-Ying; Zhang, Jun-Yu; Luo, Yu-Zhen; Sun, Hsin-Yun; Chang, Sui-Yuan; Lin, Shu-Wen; Hung, Chien-Ching

    2014-01-01

    Wide inter-patient variation of plasma efavirenz (EFV) concentrations has been observed, and a substantial proportion of HIV-positive patients may have unnecessarily higher plasma EFV concentrations than recommended while receiving EFV-containing combination antiretroviral therapy (cART) at the currently recommended daily dose of 600 mg. A lower daily dose (400 mg) of EFV has recently been demonstrated to be as efficacious as the recommended 600 mg when combined with tenofovir/mtricitabine in a multinational clinical trial, with a lower incidence of adverse effects. We aimed to use a therapeutic drug monitoring (TDM)-guided strategy to optimize the EFV dose in HIV-positive Taiwanese patients. The plasma EFV concentrations at 12 hours (C12) after taking the previous dose were determined among HIV-positive adults who had received EFV-containing cART with viral suppression (plasma HIV RNA load (PVL) EFV C12 >2.0 mg/L, EFV (Stocrit, MSD) was reduced to half a tablet daily. Determinations of EFV C12 were repeated 4-12 weeks after switch using high-performance liquid chromatography. CYP2B6 G516T polymorphisms were determined using polymerase-chain-reaction restriction fragment-length polymorphism. Between April 2013 and June 2014, 111 patients (95.5% male; mean age, 39 years; 96.4% with PVL 2.0 mg/L were switched to a reduced dose (1/2# hs) of EFV; 45.5% of them had CYP2B6 G516T or TT genotypes; and 32.4% weighed 60 kg or less. The mean baseline EFV C12 before switch was 3.65 mg/L (interquartile range (IQR), 2.62-4.17) for 111 patients, which decreased to 1.96 mg/L (IQR, 1.53-2.33) for 64 patients who had completed follow-up of C12 EFV 4 weeks after switch, with a reduction of 49.4% (IQR, 38.9-57.0%). As of 10 July, 2014, all of the 38 patients (100%) who had completed at least one follow-up of PVL achieved undetectable PVL (EFV after a mean observation of 13 weeks (IQR, 7-15 weeks). Switch to cART containing a half tablet of EFV (1/2#) in HIV-positive Taiwanese patients

  5. Costing the distribution of insecticide-treated nets: a review of cost and cost-effectiveness studies to provide guidance on standardization of costing methodology

    Directory of Open Access Journals (Sweden)

    Hanson Kara

    2006-05-01

    Full Text Available Abstract Background Insecticide-treated nets (ITNs are an effective and cost-effective means of malaria control. Scaling-up coverage of ITNs is challenging. It requires substantial resources and there are a number of strategies to choose from. Information on the cost of different strategies is still scarce. To guide the choice of a delivery strategy (or combination of strategies, reliable and standardized cost information for the different options is required. Methods The electronic online database PubMed was used for a systematic search of the published English literature on costing and economic evaluations of ITN distribution programmes. The keywords used were: net, bednet, insecticide, treated, ITN, cost, effectiveness, economic and evaluation. Identified papers were analysed to determine and evaluate the costing methods used. Methods were judged against existing standards of cost analysis to arrive at proposed standards for undertaking and presenting cost analyses. Results Cost estimates were often not readily comparable or could not be adjusted to a different context. This resulted from the wide range of methods applied and measures of output chosen. Most common shortcomings were the omission of certain costs and failure to adjust financial costs to generate economic costs. Generalisability was hampered by authors not reporting quantities and prices of resources separately and not examining the sensitivity of their results to variations in underlying assumptions. Conclusion The observed shortcomings have arisen despite the abundance of literature and guidelines on costing of health care interventions. This paper provides ITN specific recommendations in the hope that these will help to standardize future cost estimates.

  6. IEEE 802.15.4 Frame Aggregation Enhancement to Provide High Performance in Life-Critical Patient Monitoring Systems.

    Science.gov (United States)

    Akbar, Muhammad Sajjad; Yu, Hongnian; Cang, Shuang

    2017-01-28

    In wireless body area sensor networks (WBASNs), Quality of Service (QoS) provision for patient monitoring systems in terms of time-critical deadlines, high throughput and energy efficiency is a challenging task. The periodic data from these systems generates a large number of small packets in a short time period which needs an efficient channel access mechanism. The IEEE 802.15.4 standard is recommended for low power devices and widely used for many wireless sensor networks applications. It provides a hybrid channel access mechanism at the Media Access Control (MAC) layer which plays a key role in overall successful transmission in WBASNs. There are many WBASN's MAC protocols that use this hybrid channel access mechanism in variety of sensor applications. However, these protocols are less efficient for patient monitoring systems where life critical data requires limited delay, high throughput and energy efficient communication simultaneously. To address these issues, this paper proposes a frame aggregation scheme by using the aggregated-MAC protocol data unit (A-MPDU) which works with the IEEE 802.15.4 MAC layer. To implement the scheme accurately, we develop a traffic patterns analysis mechanism to understand the requirements of the sensor nodes in patient monitoring systems, then model the channel access to find the performance gap on the basis of obtained requirements, finally propose the design based on the needs of patient monitoring systems. The mechanism is initially verified using numerical modelling and then simulation is conducted using NS2.29, Castalia 3.2 and OMNeT++. The proposed scheme provides the optimal performance considering the required QoS.

  7. Real-Time 3D Image Guidance Using a Standard LINAC: Measured Motion, Accuracy, and Precision of the First Prospective Clinical Trial of Kilovoltage Intrafraction Monitoring-Guided Gating for Prostate Cancer Radiation Therapy

    DEFF Research Database (Denmark)

    Keall, Paul J; Ng, Jin Aun; Juneja, Prabhjot

    2016-01-01

    PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a new real-time 3-dimensional image guidance method. Unlike previous real-time image guidance methods, KIM uses a standard linear accelerator without any additional equipment needed. The first prospective clinical trial of KIM is underway...... for prostate cancer radiation therapy. In this paper we report on the measured motion accuracy and precision using real-time KIM-guided gating. METHODS AND MATERIALS: Imaging and motion information from the first 200 fractions from 6 patient prostate cancer radiation therapy volumetric modulated arc therapy...... treatments were analyzed. A 3-mm/5-second action threshold was used to trigger a gating event where the beam is paused and the couch position adjusted to realign the prostate to the treatment isocenter. To quantify the in vivo accuracy and precision, KIM was compared with simultaneously acquired k...

  8. Quality Assurance Guidance for the Collection of Meteorological Data Using Passive Radiometers

    Science.gov (United States)

    This document augments the February 2000 guidance entitled Meteorological Monitoring Guidance for Regulatory Modeling Applications and the March 2008 guidance entitled Quality Assurance Handbook for Air Pollution Measurement Systems Volume IV: Meteorological Measurements Version ...

  9. CDM Convective Forecast Planning guidance

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The CDM Convective Forecast Planning (CCFP) guidance product provides a foreast of en-route aviation convective hazards. The forecasts are updated every 2 hours and...

  10. A cooled CCD camera-based protocol provides an effective solution for in vitro monitoring of luciferase.

    Science.gov (United States)

    Afshari, Amirali; Uhde-Stone, Claudia; Lu, Biao

    2015-03-13

    Luciferase assay has become an increasingly important technique to monitor a wide range of biological processes. However, the mainstay protocols require a luminometer to acquire and process the data, therefore limiting its application to specialized research labs. To overcome this limitation, we have developed an alternative protocol that utilizes a commonly available cooled charge-coupled device (CCCD), instead of a luminometer for data acquiring and processing. By measuring activities of different luciferases, we characterized their substrate specificity, assay linearity, signal-to-noise levels, and fold-changes via CCCD. Next, we defined the assay parameters that are critical for appropriate use of CCCD for different luciferases. To demonstrate the usefulness in cultured mammalian cells, we conducted a case study to examine NFκB gene activation in response to inflammatory signals in human embryonic kidney cells (HEK293 cells). We found that data collected by CCCD camera was equivalent to those acquired by luminometer, thus validating the assay protocol. In comparison, The CCCD-based protocol is readily amenable to live-cell and high-throughput applications, offering fast simultaneous data acquisition and visual and quantitative data presentation. In conclusion, the CCCD-based protocol provides a useful alternative for monitoring luciferase reporters. The wide availability of CCCD will enable more researchers to use luciferases to monitor and quantify biological processes. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Capability of a Mobile Monitoring System to Provide Real-Time Data Broadcasting and Near Real-Time Source Attribution

    Science.gov (United States)

    Erickson, M.; Olaguer, J.; Wijesinghe, A.; Colvin, J.; Neish, B.; Williams, J.

    2014-12-01

    It is becoming increasingly important to understand the emissions and health effects of industrial facilities. Many areas have no or limited sustained monitoring capabilities, making it difficult to quantify the major pollution sources affecting human health, especially in fence line communities. Developments in real-time monitoring and micro-scale modeling offer unique ways to tackle these complex issues. This presentation will demonstrate the capability of coupling real-time observations with micro-scale modeling to provide real-time information and near real-time source attribution. The Houston Advanced Research Center constructed the Mobile Acquisition of Real-time Concentrations (MARC) laboratory. MARC consists of a Ford E-350 passenger van outfitted with a Proton Transfer Reaction Mass Spectrometer (PTR-MS) and meteorological equipment. This allows for the fast measurement of various VOCs important to air quality. The data recorded from the van is uploaded to an off-site database and the information is broadcast to a website in real-time. This provides for off-site monitoring of MARC's observations, which allows off-site personnel to provide immediate input to the MARC operators on how to best achieve project objectives. The information stored in the database can also be used to provide near real-time source attribution. An inverse model has been used to ascertain the amount, location, and timing of emissions based on MARC measurements in the vicinity of industrial sites. The inverse model is based on a 3D micro-scale Eulerian forward and adjoint air quality model known as the HARC model. The HARC model uses output from the Quick Urban and Industrial Complex (QUIC) wind model and requires a 3D digital model of the monitored facility based on lidar or industrial permit data. MARC is one of the instrument platforms deployed during the 2014 Benzene and other Toxics Exposure Study (BEE-TEX) in Houston, TX. The main goal of the study is to quantify and explain the

  12. Tracking working status of HIV/AIDS-trained service providers by means of a training information monitoring system in Ethiopia

    Directory of Open Access Journals (Sweden)

    Nadew Mesrak

    2009-04-01

    Full Text Available Abstract Background The Federal Ministry of Health of Ethiopia is implementing an ambitious and rapid scale-up of health care services for the prevention, care and treatment of HIV/AIDS in public facilities. With support from the United States President's Emergency Plan for AIDS Relief, 38 830 service providers were trained, from early 2005 until December 2007, in HIV-related topics. Anecdotal evidence suggested high attrition rates of providers, but reliable quantitative data have been limited. Methods With that funding, Jhpiego supports a Training Information Monitoring System, which stores training information for all HIV/AIDS training events supported by the same funding source. Data forms were developed to capture information on providers' working status and were given to eight partners who collected data during routine site visits on individual providers about working status; if not working at the facility, date of and reason for leaving; and source of information. Results Data were collected on 1744 providers (59% males in 53 hospitals and 45 health centres in 10 regional and administrative states. The project found that 32.6% of the providers were no longer at the site, 57.6% are still working on HIV/AIDS services at the same facility where they were trained and 10.4% are at the facility, but not providing HIV/AIDS services. Of the providers not at the facility, the two largest groups were those who had left for further study (27.6% and those who had gone to another public facility (17.6%. Of all physicians trained, 49.2% had left the facility. Regional and cadre variation was found, for example Gambella had the highest percent of providers no longer at the site (53.7% while Harari had the highest percentage of providers still working on HIV/AIDS (71.6%. Conclusion Overall, the project found that the information in the Training Information Monitoring System can be used to track the working status of trained providers. Data generated from

  13. Guidance in Business Process Modelling

    Science.gov (United States)

    Bartho, Andreas; Gröner, Gerd; Rahmani, Tirdad; Zhao, Yuting; Zivkovic, Srdjan

    This chapter shows how process modellers can be supported by guidance. If a telecommunication provider introduces a value-added service, this might involve the establishment of new business processes, whose specification is not trivial. A guidance engine can help a process engineer develop a new business process by stepwise refining, i.e. creating a more concrete version of the process from an abstract version. The guidance engine identifies inconsistencies and proposes possible refinement steps. The topics covered in this chapter range from theoretical foundations of business process refinement over the formalisation of refinement problems in ontologies to implementation issues. The presented solutions were developed in the MOST project.

  14. The health reform monitoring survey: addressing data gaps to provide timely insights into the affordable care act.

    Science.gov (United States)

    Long, Sharon K; Kenney, Genevieve M; Zuckerman, Stephen; Goin, Dana E; Wissoker, Douglas; Blavin, Fredric; Blumberg, Linda J; Clemans-Cope, Lisa; Holahan, John; Hempstead, Katherine

    2014-01-01

    The Health Reform Monitoring Survey (HRMS) was launched in 2013 as a mechanism to obtain timely information on the Affordable Care Act (ACA) during the period before federal government survey data for 2013 and 2014 will be available. Based on a nationally representative, probability-based Internet panel, the HRMS provides quarterly data for approximately 7,400 nonelderly adults and 2,400 children on insurance coverage, access to health care, and health care affordability, along with special topics of relevance to current policy and program issues in each quarter. For example, HRMS data from summer 2013 show that more than 60 percent of those targeted by the health insurance exchanges struggle with understanding key health insurance concepts. This raises concerns about some people's ability to evaluate trade-offs when choosing health insurance plans. Assisting people as they attempt to enroll in health coverage will require targeted education efforts and staff to support those with low health insurance literacy.

  15. Reliability history of the Apollo guidance computer

    Science.gov (United States)

    Hall, E. C.

    1972-01-01

    The Apollo guidance computer was designed to provide the computation necessary for guidance, navigation and control of the command module and the lunar landing module of the Apollo spacecraft. The computer was designed using the technology of the early 1960's and the production was completed by 1969. During the development, production, and operational phase of the program, the computer has accumulated a very interesting history which is valuable for evaluating the technology, production methods, system integration, and the reliability of the hardware. The operational experience in the Apollo guidance systems includes 17 computers which flew missions and another 26 flight type computers which are still in various phases of prelaunch activity including storage, system checkout, prelaunch spacecraft checkout, etc. These computers were manufactured and maintained under very strict quality control procedures with requirements for reporting and analyzing all indications of failure. Probably no other computer or electronic equipment with equivalent complexity has been as well documented and monitored. Since it has demonstrated a unique reliability history, it is important to evaluate the techniques and methods which have contributed to the high reliability of this computer.

  16. Highly sensitive monitoring of chest wall dynamics and acoustics provides diverse valuable information for evaluating ventilation and diagnosing pneumothorax.

    Science.gov (United States)

    Pesin, Jimy; Faingersh, Anna; Waisman, Dan; Landesberg, Amir

    2014-06-15

    Current practice of monitoring lung ventilation in neonatal intensive care units, utilizing endotracheal tube pressure and flow, end-tidal CO2, arterial O2 saturation from pulse oximetry, and hemodynamic indexes, fails to account for asymmetric pathologies and to allow for early detection of deteriorating ventilation. This study investigated the utility of bilateral measurements of chest wall dynamics and sounds, in providing early detection of changes in the mechanics and distribution of lung ventilation. Nine healthy New Zealand rabbits were ventilated at a constant pressure, while miniature accelerometers were attached to each side of the chest. Slowly progressing pneumothorax was induced by injecting 1 ml/min air into the pleural space on either side of the chest. The end of the experiment (tPTX) was defined when arterial O2 saturation from pulse oximetry dropped acoustics provide novel information that is sensitive to asymmetric changes in ventilation, enabling early detection and localization of pneumothorax. Copyright © 2014 the American Physiological Society.

  17. 76 FR 55927 - Draft Guidance for Industry and Food and Drug Administration Staff; Demonstrating the Substantial...

    Science.gov (United States)

    2011-09-09

    ... draft guidance provides responses to questions FDA has received on the Family Smoking Prevention [email protected] . SUPPLEMENTARY INFORMATION: I. Background This draft guidance provides responses to...

  18. National Protocol Framework for the Inventory and Monitoring of Waterbirds and their Habitats:An Integrated Waterbird Management and Monitoring (IWMM) Approach [In Review

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This protocol framework provides guidance for conducting inventories or monitoring surveys of waterbird habitat conditions and use at local scale in a way that will...

  19. Brookhaven National Laboratory environmental monitoring plan for Calendar Year 1996

    Energy Technology Data Exchange (ETDEWEB)

    Naidu, J.R.; Paquette, D.; Lee, R. [and others

    1996-10-01

    As required by DOE Order 5400.1, each U.S. Department of Energy (DOE) site, facility, or activity that uses, generates, releases, or manages significant quantities of hazardous materials shall provide a written Environmental Monitoring Plan (EMP) covering effluent monitoring and environmental surveillance. DOE/EH-0173T, Environmental Regulatory Guide for Radiological Effluent Monitoring and Environmental Surveillance, provides specific guidance regarding environmental monitoring activities.

  20. OVERVIEW OF SCHOOL GUIDANCE AND COUNSELLING SERVICES

    OpenAIRE

    Donald A. Odeleye

    2017-01-01

    Education in the broadest sense is aimed at helping individuals become more productive members of the society. At the heart of the whole pedagogy is Guidance and Counselling, which has been positively correlated with effective learning outcomes. Primarily, School Guidance and Counselling services are geared towards helping students know themselves, the world around them and make optimal decisions for enhanced future for all. This paper presents guidance and counselling services provided in th...

  1. Launch flexibility using NLP guidance and remote wind sensing

    Science.gov (United States)

    Cramer, Evin J.; Bradt, Jerre E.; Hardtla, John W.

    1990-01-01

    This paper examines the use of lidar wind measurements in the implementation of a guidance strategy for a nonlinear programming (NLP) launch guidance algorithm. The NLP algorithm uses B-spline command function representation for flexibility in the design of the guidance steering commands. Using this algorithm, the guidance system solves a two-point boundary value problem at each guidance update. The specification of different boundary value problems at each guidance update provides flexibility that can be used in the design of the guidance strategy. The algorithm can use lidar wind measurements for on pad guidance retargeting and for load limiting guidance steering commands. Examples presented in the paper use simulated wind updates to correct wind induced final orbit errors and to adjust the guidance steering commands to limit the product of the dynamic pressure and angle-of-attack for launch vehicle load alleviation.

  2. Design of a monitoring system and its cost-effectiveness : optimization of biodiversity monitoring through close collaboration of users and data providers

    NARCIS (Netherlands)

    Blust, De G.; Laurijssens, G.; Calster, Van H.; Verschelde, P.; Bauwens, B.; Svensson, J.; Jongman, R.H.G.

    2013-01-01

    At the European policy level there is demand for an international framework for surveillance and monitoring of biodiversity, indicating the growing need to quantify biodiversity composition and dynamics at large spatial and temporal scales to bridge the gap between international commitments and

  3. National Protocol Framework for the Inventory and Monitoring of Migratory Shorebirds [In Review

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This protocol framework provides guidance for conducting inventory and monitoring of migrating and wintering shorebirds in all potential habitats at multiple...

  4. National Protocol Framework for the Inventory and Monitoring of Breeding Landbirds Using Point Counts

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This protocol framework provides a tool for deleoping site-specific guidance on how to inventory or monitor breeding landbirds in North America by use of point...

  5. Evidence of a plate-wide tectonic pressure pulse provided by extensometric monitoring in the Balkan Mountains (Bulgaria

    Directory of Open Access Journals (Sweden)

    Briestenský Miloš

    2015-10-01

    Full Text Available The EU-TecNet monitoring network uses customized three-dimensional extensometers to record transient deformations across individual faults. This paper presents the first results from two newly established monitoring points in the Balkan Mountains in Bulgaria. The data from Saeva Dupka, recorded across an EEN-WWS striking fault, show sinistral strike-slip along the fault and subsidence of the southern block. Much of the subsidence occurred around the time of the distal MW = 5.6 Pernik Earthquake. An important transient deformation event, which began in autumn 2012, was reflected by significant compression and following extension, across the monitored fault. The data from Bacho Kiro, recorded across a NE–SW striking fault, show sinistral strike-slip along the fault and subsidence of the north-western block. The same important deformation event was reflected by changes in the strike-slip, dip-slip, and horizontal opening/closing trends. These results have been compared to data from other monitoring points in the Western Carpathians, External Dinarides, and Tian Shan. Many of the sites show evidence of simultaneous displacement anomalies and this observation is interpreted as a reflection of the plate-wide propagation of a tectonic pressure pulse towards the end of 2012.

  6. Information architecture. Volume 3: Guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The purpose of this document, as presented in Volume 1, The Foundations, is to assist the Department of Energy (DOE) in developing and promulgating information architecture guidance. This guidance is aimed at increasing the development of information architecture as a Departmentwide management best practice. This document describes departmental information architecture principles and minimum design characteristics for systems and infrastructures within the DOE Information Architecture Conceptual Model, and establishes a Departmentwide standards-based architecture program. The publication of this document fulfills the commitment to address guiding principles, promote standard architectural practices, and provide technical guidance. This document guides the transition from the baseline or defacto Departmental architecture through approved information management program plans and budgets to the future vision architecture. This document also represents another major step toward establishing a well-organized, logical foundation for the DOE information architecture.

  7. Managing Student Behavior during Large Group Guidance: What Works Best?

    Science.gov (United States)

    Quarto, Christopher J.

    2007-01-01

    Participants provided information pertaining to managing non-task-related behavior of students during large group guidance lessons. In particular, school counselors were asked often how often they provide large group guidance, the frequency of which students exhibit off-task and/or disruptive behavior during guidance lessons, and techniques they…

  8. GUIDANCE ON SELECTING AGE GROUPS FOR ...

    Science.gov (United States)

    This guidance document provides a set of early-lifestage age groups for Environmental Protection Agency scientists to consider when assessing children’s exposure to environmental contaminants and the resultant potential dose. These recommended age groups are based on current understanding of differences in behavior and physiology which may impact exposures in children. A consistent set of early-life age groups, supported by an underlying scientific rationale, is expected to improve Agency exposure and risk assessments for children by increasing the consistency and comparability of risk assessments across the Agency; by improving accuracy and transparency in assessments for those cases where current practice might too broadly combine behaviorally and physiologically disparate age groups; and by fostering a consistent approach to future exposure surveys and monitoring efforts to generate improved exposure factors for children. see description

  9. Guidance for performing preliminary assessments under CERCLA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-09-01

    EPA headquarters and a national site assessment workgroup produced this guidance for Regional, State, and contractor staff who manage or perform preliminary assessments (PAs). EPA has focused this guidance on the types of sites and site conditions most commonly encountered. The PA approach described in this guidance is generally applicable to a wide variety of sites. However, because of the variability among sites, the amount of information available, and the level of investigative effort required, it is not possible to provide guidance that is equally applicable to all sites. PA investigators should recognize this and be aware that variation from this guidance may be necessary for some sites, particularly for PAs performed at Federal facilities, PAs conducted under EPA`s Environmental Priorities Initiative (EPI), and PAs at sites that have previously been extensively investigated by EPA or others. The purpose of this guidance is to provide instructions for conducting a PA and reporting results. This guidance discusses the information required to evaluate a site and how to obtain it, how to score a site, and reporting requirements. This document also provides guidelines and instruction on PA evaluation, scoring, and the use of standard PA scoresheets. The overall goal of this guidance is to assist PA investigators in conducting high-quality assessments that result in correct site screening or further action recommendations on a nationally consistent basis.

  10. 78 FR 73200 - Draft Guidance for Industry on Bioequivalence Recommendations for Paliperidone Palmitate Extended...

    Science.gov (United States)

    2013-12-05

    ...). The draft guidance, when finalized, will represent the Agency's current thinking on the design of BE... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Bioequivalence... for Paliperidone Palmitate.'' The guidance provides specific recommendations on the design of...

  11. 78 FR 55263 - Draft Guidance for Industry on Bioequivalence Recommendations for Fluticasone Propionate...

    Science.gov (United States)

    2013-09-10

    ....115). The draft guidance, when finalized, will represent the Agency's current thinking on the design... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Bioequivalence... Propionate; Salmeterol Xinafoate.'' The recommendations provide specific guidance on the design of...

  12. Monitoring

    Science.gov (United States)

    ... Heart Disease and Diabetes Blood Glucose Monitoring Insulin Injection Resources Mental Health and Diabetes Healthy Holiday Eating Lifestyle Resources Improve Medication Taking Spanish Language Resources AADE7 Self-Care Behaviors ...

  13. Career guidance in communities

    DEFF Research Database (Denmark)

    Thomsen, Rie

    from a critical psychological standpoint the paper introduces a social practice theory of career guidance. The social practice theory of career guidance argues that career guidance can be seen as a collective practice in which people can join forces with career guidance practitioners to analyse...... their situation and based on these insights create new opportunities in relation to their future educational or vocational participation in society (Thomsen 2012). From this idea, the second part of the paper the paper moves on to consider the practical implications of taking the collective as the starting point...

  14. Question No. 5: What Role Can Satellites Take, as a Complement to Ground Based Measurement Systems, to Provide Sustained Observations to Monitor GHG Emissions?

    Science.gov (United States)

    Chahine, Moustafa; Olsen, Edward

    2011-01-01

    What role can satellites take, as a complement to ground based measurement systems, to provide sustained observations to monitor GHG emissions (e.g., CO2, CH4, O3, N2O, CFC s, NH3, and NF3) that contribute to global warming?

  15. A computerised sampling strategy for therapeutic drug monitoring of lithium provides precise estimates and significantly reduces dose-finding time

    DEFF Research Database (Denmark)

    Høgberg, Lotte Christine Groth; Jürgens, Gesche; Zederkof, Vivian Wederking

    2012-01-01

    citrate. Bayesian approach was performed in the intervention groups, and estimation of lithium steady-state trough concentration was obtained from non-steady-state blood sample, collected about 12 hr after the first lithium study dose. The estimate was compared with the actually measured steady......-state concentration. In the control group, lithium monitoring was traditionally performed as steady-state blood sampling. Predicted and measured lithium concentrations were comparable. The desired lithium dose was reached significantly faster in the intervention group compared to control; 2.47 ± 2.22 days versus 9.......96 ± 11.24 days (mean ± S.D.) (p = 0.0003). Bayesian approach was an advantage for the clinicians as a fast and safe aid to obtain the optimal lithium treatment dose....

  16. Surface Water Treatment Rules State Implementation Guidance

    Science.gov (United States)

    These documents provide guidance to states, tribes and U.S. EPA Regions exercising primary enforcement responsibility under the Safe Drinking Water Act. The documents contain EPA’s recommendations for implementation of the Surface Water Treatment Rules.

  17. The Industrial User Permitting Guidance Manual

    Science.gov (United States)

    Provides guidance for control authorities to effectively develop and issue control mechanisms to IUs discharging to the POTW and covers developing and implementing control mechanisms for both SIUs and non-SIUs.

  18. Wells provide a distorted view of life in the aquifer: implications for sampling, monitoring and assessment of groundwater ecosystems

    Science.gov (United States)

    Korbel, Kathryn; Chariton, Anthony; Stephenson, Sarah; Greenfield, Paul; Hose, Grant C.

    2017-01-01

    When compared to surface ecosystems, groundwater sampling has unique constraints, including limited access to ecosystems through wells. In order to monitor groundwater, a detailed understanding of groundwater biota and what biological sampling of wells truly reflects, is paramount. This study aims to address this uncertainty, comparing the composition of biota in groundwater wells prior to and after purging, with samples collected prior to purging reflecting a potentially artificial environment and samples collected after purging representing the surrounding aquifer. This study uses DNA community profiling (metabarcoding) of 16S rDNA and 18S rDNA, combined with traditional stygofauna sampling methods, to characterise groundwater biota from four catchments within eastern Australia. Aquifer waters were dominated by Archaea and bacteria (e.g. Nitrosopumilales) that are often associated with nitrification processes, and contained a greater proportion of bacteria (e.g. Anaerolineales) associated with fermenting processes compared to well waters. In contrast, unpurged wells contained greater proportions of pathogenic bacteria and bacteria often associated with denitrification processes. In terms of eukaryotes, the abundances of copepods, syncarids and oligochaetes and total abundances of stygofauna were greater in wells than aquifers. These findings highlight the need to consider sampling requirements when completing groundwater ecology surveys.

  19. Guidance for implementing the long-term surveillance program for UMTRA Project Title I Disposal Sites

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    This guidance document has two purposes: it provides guidance for writing site-specific long-term surveillance plans (LTSP) and it describes site surveillance, monitoring, and long-term care techniques for Title I disposal sites of the Uranium Mill Tailings Radiation Control Act (UMTRCA) (42 USC Section 7901 et seq.). Long-term care includes monitoring, maintenance, and emergency measures needed to protect public health and safety and the environment after remedial action is completed. This document applies to the UMTRCA-designated Title I disposal sites. The requirements for long-term care of the Title I sites and the contents of the LTSPs are provided in U.S. Nuclear Regulatory Commission (NRC) regulations (10 CFR Section 40.27) provided in Attachment 1.

  20. Automated Catheter Navigation With Electromagnetic Image Guidance.

    Science.gov (United States)

    Jaeger, Herman A; Nardelli, Pietro; O'Shea, Conor; Tugwell, Josef; Khan, Kashif A; Power, Timothy; O'Shea, Michael; Kennedy, Marcus P; Cantillon-Murphy, Padraig

    2017-08-01

    This paper describes a novel method of controlling an endoscopic catheter by using an automated catheter tensioning system with the objective of providing clinicians with improved manipulation capabilities within the patient. Catheters are used in many clinical procedures to provide access to the cardiopulmonary system. Control of such catheters is performed manually by the clinicians using a handle, typically actuating a single or opposing set of pull wires. Such catheters are generally actuated in a single plane, requiring the clinician to rotate the catheter handle to navigate the system. The automation system described here allows closed-loop control of a custom bronchial catheter in tandem with an electromagnetic tracking of the catheter tip and image guidance by using a 3D Slicer. An electromechanical drive train applies tension to four pull wires to steer the catheter tip, with the applied force constantly monitored through force sensing load cells. The applied tension is controlled through a PC connected joystick. An electromagnetic sensor embedded in the catheter tip enables constant real-time position tracking, whereas a working channel provides a route for endoscopic instruments. The system is demonstrated and tested in both a breathing lung model and a preclinical animal study. Navigation to predefined targets in the subject's airways by using the joystick while using virtual image guidance and electromagnetic tracking was demonstrated. Average targeting times were 29 and 10 s, respectively, for the breathing lung and live animal studies. This paper presents the first reported remote controlled bronchial working channel catheter utilizing electromagnetic tracking and has many implications for future development in endoscopic and catheter-based procedures.

  1. Landsat ETM+ and SRTM Data Provide Near Real-Time Monitoring of Chimpanzee (Pan troglodytes Habitats in Africa

    Directory of Open Access Journals (Sweden)

    Samuel M. Jantz

    2016-05-01

    Full Text Available All four chimpanzee sub-species populations are declining due to multiple factors including human-caused habitat loss. Effective conservation efforts are therefore needed to ensure their long-term survival. Habitat suitability models serve as useful tools for conservation planning by depicting relative environmental suitability in geographic space over time. Previous studies mapping chimpanzee habitat suitability have been limited to small regions or coarse spatial and temporal resolutions. Here, we used Random Forests regression to downscale a coarse resolution habitat suitability calibration dataset to estimate habitat suitability over the entire chimpanzee range at 30-m resolution. Our model predicted habitat suitability well with an r2 of 0.82 (±0.002 based on 50-fold cross validation where 75% of the data was used for model calibration and 25% for model testing; however, there was considerable variation in the predictive capability among the four sub-species modeled individually. We tested the influence of several variables derived from Landsat Enhanced Thematic Mapper Plus (ETM+ that included metrics of forest canopy and structure for four three-year time periods between 2000 and 2012. Elevation, Landsat ETM+ band 5 and Landsat derived canopy cover were the strongest predictors; highly suitable areas were associated with dense tree canopy cover for all but the Nigeria-Cameroon and Central Chimpanzee sub-species. Because the models were sensitive to such temporally based predictors, our results are the first to highlight the value of integrating continuously updated variables derived from satellite remote sensing into temporally dynamic habitat suitability models to support  near real-time monitoring of habitat status and decision support systems.

  2. Simplifying ART cohort monitoring: Can pharmacy stocks provide accurate estimates of patients retained on antiretroviral therapy in Malawi?

    Directory of Open Access Journals (Sweden)

    Tweya Hannock

    2012-07-01

    Full Text Available Abstract Background Routine monitoring of patients on antiretroviral therapy (ART is crucial for measuring program success and accurate drug forecasting. However, compiling data from patient registers to measure retention in ART is labour-intensive. To address this challenge, we conducted a pilot study in Malawi to assess whether patient ART retention could be determined using pharmacy records as compared to estimates of retention based on standardized paper- or electronic based cohort reports. Methods Twelve ART facilities were included in the study: six used paper-based registers and six used electronic data systems. One ART facility implemented an electronic data system in quarter three and was included as a paper-based system facility in quarter two only. Routine patient retention cohort reports, paper or electronic, were collected from facilities for both quarter two [April–June] and quarter three [July–September], 2010. Pharmacy stock data were also collected from the 12 ART facilities over the same period. Numbers of ART continuation bottles recorded on pharmacy stock cards at the beginning and end of each quarter were documented. These pharmacy data were used to calculate the total bottles dispensed to patients in each quarter with intent to estimate the number of patients retained on ART. Information for time required to determine ART retention was gathered through interviews with clinicians tasked with compiling the data. Results Among ART clinics with paper-based systems, three of six facilities in quarter two and four of five facilities in quarter three had similar numbers of patients retained on ART comparing cohort reports to pharmacy stock records. In ART clinics with electronic systems, five of six facilities in quarter two and five of seven facilities in quarter three had similar numbers of patients retained on ART when comparing retention numbers from electronically generated cohort reports to pharmacy stock records. Among

  3. BENCHMARK DOSE TECHNICAL GUIDANCE DOCUMENT ...

    Science.gov (United States)

    The U.S. EPA conducts risk assessments for an array of health effects that may result from exposure to environmental agents, and that require an analysis of the relationship between exposure and health-related outcomes. The dose-response assessment is essentially a two-step process, the first being the definition of a point of departure (POD), and the second extrapolation from the POD to low environmentally-relevant exposure levels. The benchmark dose (BMD) approach provides a more quantitative alternative to the first step in the dose-response assessment than the current NOAEL/LOAEL process for noncancer health effects, and is similar to that for determining the POD proposed for cancer endpoints. As the Agency moves toward harmonization of approaches for human health risk assessment, the dichotomy between cancer and noncancer health effects is being replaced by consideration of mode of action and whether the effects of concern are likely to be linear or nonlinear at low doses. Thus, the purpose of this project is to provide guidance for the Agency and the outside community on the application of the BMD approach in determining the POD for all types of health effects data, whether a linear or nonlinear low dose extrapolation is used. A guidance document is being developed under the auspices of EPA's Risk Assessment Forum. The purpose of this project is to provide guidance for the Agency and the outside community on the application of the benchmark dose (BMD) appr

  4. Appraising the Early-est earthquake monitoring system for tsunami alerting at the Italian Candidate Tsunami Service Provider

    Science.gov (United States)

    Bernardi, F.; Lomax, A.; Michelini, A.; Lauciani, V.; Piatanesi, A.; Lorito, S.

    2015-09-01

    In this paper we present and discuss the performance of the procedure for earthquake location and characterization implemented in the Italian Candidate Tsunami Service Provider at the Istituto Nazionale di Geofisica e Vulcanologia (INGV) in Rome. Following the ICG/NEAMTWS guidelines, the first tsunami warning messages are based only on seismic information, i.e., epicenter location, hypocenter depth, and magnitude, which are automatically computed by the software Early-est. Early-est is a package for rapid location and seismic/tsunamigenic characterization of earthquakes. The Early-est software package operates using offline-event or continuous-real-time seismic waveform data to perform trace processing and picking, and, at a regular report interval, phase association, event detection, hypocenter location, and event characterization. Early-est also provides mb, Mwp, and Mwpd magnitude estimations. mb magnitudes are preferred for events with Mwp ≲ 5.8, while Mwpd estimations are valid for events with Mwp ≳ 7.2. In this paper we present the earthquake parameters computed by Early-est between the beginning of March 2012 and the end of December 2014 on a global scale for events with magnitude M ≥ 5.5, and we also present the detection timeline. We compare the earthquake parameters automatically computed by Early-est with the same parameters listed in reference catalogs. Such reference catalogs are manually revised/verified by scientists. The goal of this work is to test the accuracy and reliability of the fully automatic locations provided by Early-est. In our analysis, the epicenter location, hypocenter depth and magnitude parameters do not differ significantly from the values in the reference catalogs. Both mb and Mwp magnitudes show differences to the reference catalogs. We thus derived correction functions in order to minimize the differences and correct biases between our values and the ones from the reference catalogs. Correction of the Mwp

  5. Coral Reef Guidance

    Science.gov (United States)

    Guidance prepared by EPA and Army Corps of Engineers concerning coral reef protection under the Clean Water Act, Marine Protection, Research, and Sanctuaries Act, Rivers and Harbors Act, and Federal Project Authorities.

  6. Pollinator Risk Assessment Guidance

    Science.gov (United States)

    This Guidance is part of a long-term strategy to advance the science of assessing the risks posed by pesticides to honey bees, giving risk managers the means to further improve pollinator protection in our regulatory decisions.

  7. RH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2008-01-12

    The purpose of this program guidance document is to provide the technical requirements for use, operation, inspection, and maintenance of the RH-TRU 72-B Waste Shipping Package (also known as the "RH-TRU 72-B cask") and directly related components. This document complies with the requirements as specified in the RH-TRU 72-B Safety Analysis Report for Packaging (SARP), and Nuclear Regulatory Commission (NRC) Certificate of Compliance (C of C) 9212. If there is a conflict between this document and the SARP and/or C of C, the C of C shall govern. The C of C states: "...each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." It further states: "...each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP tasks the Waste Isolation Pilot Plant (WIPP) Management and Operating (M&O) Contractor with assuring the packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8, "Deliberate Misconduct." Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required.In accordance with 10 CFR Part 71, "Packaging and Transportation of Radioactive Material," certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21, "Reporting of Defects and Noncompliance," regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a

  8. RH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2006-11-07

    The purpose of this program guidance document is to provide the technical requirements for use, operation, inspection, and maintenance of the RH-TRU 72-B Waste Shipping Package and directly related components. This document complies with the requirements as specified in the RH-TRU 72-B Safety Analysis Report for Packaging (SARP), and Nuclear Regulatory Commission (NRC) Certificate of Compliance (C of C) 9212. If there is a conflict between this document and the SARP and/or C of C, the C of C shall govern. The C of C states: "...each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." It further states: "...each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP tasks the Waste Isolation Pilot Plant (WIPP) Management and Operating (M&O) Contractor with assuring the packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with 10 Code of Federal Regulations (CFR) §71.8, "Deliberate Misconduct." Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) shall be notified immediately. CBFO will evaluate the issue and notify the NRC if required. In accordance with 10 CFR Part 71, "Packaging and Transportation of Radioactive Material," certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21, "Reporting of Defects and Noncompliance," regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to

  9. Bull trout recovery: Monitoring and evaluation guidance

    Science.gov (United States)

    U.S. Fish and Wildlife Service (USFWS)

    2008-01-01

    Bull trout (Salvelinus confluentus) is an imperiled species of char native to the Pacific Northwest. Combinations of habitat degradation (e.g., Fraley and Shepard 1989), barriers to migration (e.g., Rieman and McIntyre 1995), and the introduction of non-natives (e.g., Leary et al. 1993) have led to the decline of bull trout populations across their...

  10. Vocational Guidance and the Labour Market: Guidance to Transform or Guidance to Domesticate?

    Science.gov (United States)

    Kann, Ulla

    1988-01-01

    Explores the conflict in guidance arising from the desire to consider the needs of society while guaranteeing individual freedom of choice. Discusses the theoretical basis of vocational guidance. Gives examples of "domestication" and "transformation" approaches to guidance and discusses the consequences of viewing guidance as a…

  11. Space guidance evolution - A personal narrative

    Science.gov (United States)

    Battin, R. H.

    1982-04-01

    The history of space guidance and navigation begins in the early 1950s when the MIT Instrumentation Laboratory was chosen to provide a self-contained guidance system backup for the new Atlas intercontinental ballistic missile. Computing developments during the 1950s are considered, taking into account the construction of the all-electronic digital computer at MIT in the early 1950s, the first algebraic compiler, and the design of an algebraic programming language. Attention is given to the Delta guidance method, the Q-system which was first implemented on the Thor IRBM, and the symmetry of the Q matrix. The effect of the launch of Sputnik on computational developments related to space guidance applications is discussed. A NASA study contract made it possible to continue work which had begun under Air Force auspices. Work related to Mars probe navigation is considered along with developments related to the race to the moon.

  12. Ability of non-invasive intermittent blood pressure monitoring and a continuous non-invasive arterial pressure monitor (CNAP™) to provide new readings in each 1-min interval during elective caesarean section under spinal anaesthesia.

    Science.gov (United States)

    McCarthy, T; Telec, N; Dennis, A; Griffiths, J; Buettner, A

    2012-03-01

    We compared the ability of automated non-invasive intermittent oscillometric blood pressure monitoring with a new device, CNAP(TM) (continuous non-invasive arterial pressure) to provide a new blood pressure reading in each 1-min interval between spinal anaesthesia and delivery during caesarean section. We also compared the accuracy of continuous non-invasive arterial pressure readings with non-invasive blood pressure measurements before spinal anaesthesia. Fifty-nine women participated. The non-invasive and continuous non-invasive monitors displayed new blood pressure readings in a mean of 82% (11%) and 83% (13%) (p = 0.97) of the one-minute intervals between spinal anaesthesia and delivery, respectively. Continuous non-invasive arterial pressure was more likely to fail on two or more consecutive minutes (p=0.001). From the pre-spinal readings, the mean bias, defined as non-invasive-continuous non-invasive arterial pressure, and limits of agreement (±2SD mean bias) for systolic, diastolic and mean blood pressure respectively were +1.3 (±26.0), -2.9 (±21.8) and +2.6 (±20.4) mmHg. The new monitor has disadvantages compared with conventional non-invasive intermittent blood pressure monitoring. Anaesthesia © 2012 The Association of Anaesthetists of Great Britain and Ireland.

  13. 78 FR 38683 - Availability of Guidance: Establishments Guidance for the Selection of a Commercial or Private...

    Science.gov (United States)

    2013-06-27

    ... required, accreditation provides increased confidence in the accuracy of the test results. Using either an... instructions in the guidance should change the definition of ``routine PT'' to reflect the reality that PT is...

  14. Comparison of Mediterranean Pteropod Shell Biometrics and Ultrastructure from Historical (1910 and 1921 and Present Day (2012 Samples Provides Baseline for Monitoring Effects of Global Change.

    Directory of Open Access Journals (Sweden)

    Ella L Howes

    Full Text Available Anthropogenic carbon perturbation has caused decreases in seawater pH and increases in global temperatures since the start of the 20th century. The subsequent lowering of the saturation state of CaCO3 may make the secretion of skeletons more problematic for marine calcifiers. As organisms that precipitate thin aragonite shells, thecosome pteropods have been identified as being particularly vulnerable to climate change effects. Coupled with their global distribution, this makes them ideal for use as sentinel organisms. Recent studies have highlighted shell dissolution as a potential indicator of ocean acidification; however, this metric is not applicable for monitoring pH changes in supersaturated basins. In this study, the novel approach of high resolution computed tomography (CT scanning was used to produce quantitative 3-dimensional renderings pteropod shells to assess the potential of using this method to monitor small changes in shell biometrics that may be driven by climate change drivers. An ontogenetic analysis of the shells of Cavolinia inflexa and Styliola subula collected from the Mediterranean was used to identify suitable monitoring metrics. Modern samples were then compared to historical samples of the same species, collected during the Mediterranean leg of the Thor (1910 and Dana (1921 cruises to assess whether any empirical differences could be detected. Shell densities were calculated and scanning electron microscopy was used to compare the aragonite crystal morphology. pH for the collection years was hind-cast using temperature and salinity time series with atmospheric CO2 concentrations from ice core data. Historical samples of S. subula were thicker than S. subula shells of the same size from 2012 and C. inflexa shells collected in 1910 were significantly denser than those from 2012. These results provide a baseline for future work to develop monitoring techniques for climate change in the oceans using the novel approach of

  15. Adaptive internal model guidance law for weaving maneuvering target.

    Science.gov (United States)

    Deng, Xiangfei; Liu, Xiangbin

    2017-09-01

    For the terminal phase guidance problem of the missile intercepting weaving maneuvering target, an adaptive internal model guidance laws in the three-dimensional (3-D) engagement space is proposed in this paper. The guidance law adopts the disturbance rejection theory by treating the target weaving maneuvering accelerations as external disturbance, which comprises of nominal part and adaptive part. The nominal part based on feedback linearization method ensures the whole guidance system stable and the adaptive part based on internal model principle is used to recover the disturbance signals on-line to reject the target maneuver asymptotically. The algorithm guarantees the whole guidance system with satisfying performance both in transient and steady state on the effect of target maneuver on guidance system. The stability analyses and theory proof are provided in this paper. At last, numerical simulations are carried out to illustrate the effectiveness of the proposed guidance law. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  16. CAREER GUIDANCE EXPERIENCE ABROAD

    Directory of Open Access Journals (Sweden)

    Sergey N. Tolstoguzov

    2015-01-01

    Full Text Available The aim of this paper is to describe the experience of careeroriented activities carried out with students of schools in developed and developing countries. Career Guidance in Russia, despite the vast experience of its implementation, is experiencing serious difficulties. In this regard, it is important to take into account the international experience career-oriented activities, such as in the developed countries of North America and the European Union as well as in several Asian countries with rapidly growing economies and a large demographic potential, taking into account the best variants for the Russian education system. Methods. The experience of career-oriented work undertaken with pupils of the USA, Canada, Israel, France, UK, Germany, Denmark, Sweden, Japan, Singapore, China and India is shown on the basis of the comparative analysis of different publications and information sources. The author has made an attempt to generalize the principles of psycho-pedagogical and administrative assistance in professional self-determination of senior pupils abroad. Scientific novelty. The approaches to career-oriented activities in countries with different levels of economic development are compared for the first time. Some principles are revealed. Firstly, the higher the income level per capita in the country, the greater attention is given to vocational guidance. The politics in the developed countries is based on interests of the individual: children’s acquaintance with the world of professions begins already at younger school and the moment of definitive selfdetermination is postponed till the end of their senior stage of education; the possibility of direction change of professional preparation in case of detection of discrepancy of qualities of the pupil to originally selected profile is provided. Career-oriented activity in developing countries, on the contrary, is rigidly coordinated to requirements of economy and a labour market

  17. RH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions, LLC

    2003-08-25

    The purpose of this program guidance document is to provide technical requirements for use, operation, inspection, and maintenance of the RH-TRU 72-B Waste Shipping Package and directly related components. This document complies with the requirements as specified in the RH-TRU 72-B Safety Analysis Report for Packaging (SARP), and Nuclear Regulatory Commission (NRC) Certificate of Compliance (C of C) 9212. If there is a conflict between this document and the SARP and/or C of C, the SARP and/or C of C shall govern. The C of C states: ''...each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, ''Operating Procedures,'' of the application.'' It further states: ''...each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, ''Acceptance Tests and Maintenance Program of the Application.'' Chapter 9.0 of the SARP tasks the Waste Isolation Pilot Plant (WIPP) Management and Operating (M&O) contractor with assuring the packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC approved, users need to be familiar with 10 CFR {section} 71.11, ''Deliberate Misconduct.'' Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. CBFO will evaluate the issue and notify the NRC if required. This document details the instructions to be followed to operate, maintain, and test the RH-TRU 72-B packaging. This Program Guidance standardizes instructions for all users. Users shall follow these instructions. Following these instructions assures that operations are safe and meet the requirements of the SARP. This document is available on the Internet at: ttp://www.ws/library/t2omi/t2omi.htm. Users are responsible for ensuring they are using the current

  18. Vocational Development and Guidance.

    Science.gov (United States)

    Tennyson, W. Wesley; And Others

    The vocational education volume considers questions of career development, the role of guidance in the school, vocational training, the relation of self-concept to vocational choice, and occupational information. Twenty-six papers deal with theories of vocational behavior, the success of vocational education programs, and testing information.…

  19. Guidance on lobbying restrictions

    Science.gov (United States)

    The purpose of this guidance is to remind nonprofit organizations, universities, and other non-government recipients of EPA grants that, with very limited exceptions, you may not use Federal grant funds or cost-sharing funds to conduct lobbying activities.

  20. PIV Logon Configuration Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Glen Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-03-04

    This document details the configurations and enhancements implemented to support the usage of federal Personal Identity Verification (PIV) Card for logon on unclassified networks. The guidance is a reference implementation of the configurations and enhancements deployed at the Los Alamos National Laboratory (LANL) by Network and Infrastructure Engineering – Core Services (NIE-CS).

  1. Career guidance on the move

    DEFF Research Database (Denmark)

    Thomsen, Rie

    2013-01-01

    This article is about how the notion of place can be used in an analysis of career guidance practices and their development. It is about how a focus on the context of career guidance can develop an awareness of the place where guidance is practiced and support the development of career guidance...... in new places. In this article I introduce an analytical perspective on place; I give the example of the guidance café a practice development that took place into serious consideration because it was an attempt to develop career guidance practice through relocating it....

  2. Physical health care monitoring for people with serious mental illness.

    Science.gov (United States)

    Tosh, Graeme; Clifton, Andrew V; Xia, Jun; White, Margueritte M

    2014-01-17

    Current guidance suggests that we should monitor the physical health of people with serious mental illness, and there has been a significant financial investment over recent years to provide this. To assess the effectiveness of physical health monitoring, compared with standard care for people with serious mental illness. We searched the Cochrane Schizophrenia Group Trials Register (October 2009, update in October 2012), which is based on regular searches of CINAHL, EMBASE, MEDLINE and PsycINFO. All randomised clinical trials focusing on physical health monitoring versus standard care, or comparing i) self monitoring versus monitoring by a healthcare professional; ii) simple versus complex monitoring; iii) specific versus non-specific checks; iv) once only versus regular checks; or v) different guidance materials. Initially, review authors (GT, AC, SM) independently screened the search results and identified three studies as possibly fulfilling the review's criteria. On examination, however, all three were subsequently excluded. Forty-two additional citations were identified in October 2012 and screened by two review authors (JX and MW), 11 of which underwent full screening. No relevant randomised trials which assess the effectiveness of physical health monitoring in people with serious mental illness have been completed. We identified one ongoing study. There is still no evidence from randomised trials to support or refute current guidance and practice. Guidance and practice are based on expert consensus, clinical experience and good intentions rather than high quality evidence.

  3. Guidance for UMTRA project surveillance and maintenance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1986-01-01

    The Guidance for UMTRA Project Surveillance and Maintenance describes the procedures that will be used to verify that Uranium Mill Tailings Remedial Action (UMTRA) Project disposal sites continue to function as designed. The approach of this guidance document is to identify surveillance requirements and maintenance procedures that will be used to comply with NRC license requirements. This document addresses five primary activities: Definition and characterization of final site conditions. Site inspections; Ground-water monitoring; Aerial photography; and Custodial maintenance and contingency repair. Final site conditions will be defined and characterized prior to the completion of remedial actions at a site. As-built drawings will be compiled, a final topographic survey will be performed, a vicinity map will be prepared, and ground and aerial photographs will be taken. Survey monuments, site markers, and signs will be established as will a network of monitoring wells.

  4. 77 FR 9947 - Guidance for Industry: Early Clinical Trials With Live Biotherapeutic Products: Chemistry...

    Science.gov (United States)

    2012-02-21

    ... Biotherapeutic Products: Chemistry, Manufacturing, and Control Information; Availability AGENCY: Food and Drug... Products: Chemistry, Manufacturing, and Control Information '' dated February 2012. The guidance provides... Products: Chemistry, Manufacturing, and Control Information'' dated February 2012. The guidance provides...

  5. Analysing Interplanetary Probe Guidance Accuracy

    Directory of Open Access Journals (Sweden)

    S. V. Sukhova

    2016-01-01

    Full Text Available The paper presents a guidance accuracy analysis and estimates delta-v budget required to provide the trajectory correction maneuvers for direct interplanetary flights (without midcourse gravity assists. The analysis takes into consideration the orbital hyperbolic injection errors (depend on a selected launch vehicle and ascent trajectory and the uncertainties of midcourse correction maneuvers.The calculation algorithm is based on Monte Carlo simulation and Danby’s matrix methods (the matrizant of keplerian motion. Danby’s method establishes a link between the errors of the spacecraft state vectors at different flight times using the reference keplerian orbit matrizant. Utilizing the nominal trajectory parameters and the covariance matrix of launch vehicle injection errors the random perturbed orbits are generated and required velocity corrections are calculated. The next step is to simulate midcourse maneuver performance uncertainty using the midcourse maneuver covariance matrix. The obtained trajectory correction impulses and spacecraft position errors are statistically processed to compute required delta-v budget and dispersions ellipse parameters for different prediction intervals.As an example, a guidance accuracy analysis has been conducted for a 2022 mission to Mars and a Venus mission in 2026. The paper considers one and two midcourse correction options, as well as utilization of two different launch vehicles.The presented algorithm based on Monte Carlo simulation and Danby’s methods provides preliminary evaluation for midcourse corrections delta-v budget and spacecraft position error. The only data required for this guidance accuracy analysis are a reference keplerian trajectory and a covariance matrix of the injection errors. Danby’s matrix method allows us to take into account also the other factors affecting the trajectory thereby increasing the accuracy of analysis.

  6. Return to competition after an Achilles tendon rupture using both on and off the field load monitoring as guidance: A case report of a top-level soccer player.

    Science.gov (United States)

    Fanchini, Maurizio; Impellizzeri, Franco M; Silbernagel, Karin Grävare; Combi, Franco; Benazzo, Franco; Bizzini, Mario

    2018-01-01

    To describe the Return to competition after Achilles Tendon rupture (ATR) in an elite soccer player. Case report. Return to sport (RTS) of a professional soccer player who suffered an ATR during a match. The RTS phase started 15 weeks after surgery and specific on-field activities were gradually introduced. Criteria used to monitor the transition through the different phases were strength and endurance of the calf muscle and ability to sustain specific on-field training loads (TL) monitored with Global Positioning System and heart-rate system. TLs were weekly compared to pre-injury values to evaluate recovery and to prescribe future sessions. A 39-year-old (height 178 cm, weight 75 kg) elite soccer defender player, playing in Italian Serie-A league. Days of absence were lower compared to a cohort presented in UEFA study (119 versus 161 ± 65 days, respectively). External-TL and Internal-TL were organized to gradually increase during RTS and resulted in higher values prior to return to competition compared to pre-injury values. Concentric plantar flexion peak torque increased till 9th months after surgery. Monitoring of the field activities allowed comparison with pre-injury values and provided a useful and functional criteria to pass return to team activity and competition. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Guidance and counselling services in federal government colleges ...

    African Journals Online (AJOL)

    The effective organization of guidance and counselling services in Nigeria would be a reality, if the federal and state Ministries of Education are able to provide professionally trained guidance counsellors, recognize their services in schools and provide them with necessary incentives and facilities. Since the Federal ...

  8. Guidance on spatial wildland fire analysis: models, tools, and techniques

    Science.gov (United States)

    Richard D. Stratton

    2006-01-01

    There is an increasing need for spatial wildland fire analysis in support of incident management, fuel treatment planning, wildland-urban assessment, and land management plan development. However, little guidance has been provided to the field in the form of training, support, or research examples. This paper provides guidance to fire managers, planners, specialists,...

  9. Environmental Guidance Program Reference Book: American Indian Religious Freedom Act

    Energy Technology Data Exchange (ETDEWEB)

    1987-11-01

    This Reference Book contains a copy of the American Indian Religious Freedom Act and guidance for DOE compliance with the statute. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically.

  10. Islamic Guidance for Drug Addiction

    Directory of Open Access Journals (Sweden)

    Agus Supriyanto

    2016-10-01

    Full Text Available Islamic Guidance is social rehabilitation program for Drug Addiction (resident. The goal of this research to know the Islamic guidance for resident at the Center for Rehabilitation of the National Narcotics Agency Lido Bogor. The methodology in this research is qualitative descriptive, with a sample two religious counselor. Can be concluded that Islamic guidance is implemented with the classical format, group format, and individual formats. The goal of the Islamic Guidance to develop religious mentally.

  11. The Lower Sevier River Basin Crop Monitor and Forecast Decision Support System: Exploiting Landsat Imagery to Provide Continuous Information to Farmers and Water Managers

    Science.gov (United States)

    Torres-Rua, A. F.; Walker, W. R.; McKee, M.

    2013-12-01

    The last century has seen a large number of innovations in agriculture such as better policies for water control and management, upgraded water conveyance, irrigation, distribution, and monitoring systems, and better weather forecasting products. In spite of this, irrigation management and irrigation water deliveries by farmers/water managers is still based on factors like water share amounts, tradition, and past experience on irrigation. These factors are not necessarily related to the actual crop water use; they are followed because of the absence of related information provided in a timely manner at an affordable cost. Thus, it is necessary to develop means to deliver continuous and personalized information about crop water requirements to water users/managers at the field and irrigation system levels so managers at these levels can better quantify the required versus available water for irrigation during the irrigation season. This study presents a new decision support system (DSS) platform that addresses the absence of information on actual crop water requirements and crop performance by providing continuous updated farm-based crop water use along with other farm performance indicators such as crop yield and farm management to irrigators and water managers. This DSS exploits the periodicity of the Landsat Satellite Mission (8 to 16 days, depending on the period of interest) to provide remote monitoring at the individual field and irrigation system levels. The Landsat satellite images are converted into information about crop water use, yield performance and field management through application of state-of-the-art semi-physical and statistical algorithms that provide this information at a pixel basis that are ultimately aggregated to field and irrigation system levels. A version of the DSS has been implemented for the agricultural lands in the Lower Sevier River, Utah, and has been operational since the beginning of the 2013 irrigation season. The main goal of

  12. [Survey on patients' satisfaction with opioid rescue guidance by pharmacists].

    Science.gov (United States)

    Takase, Hisamitsu; Kawade, Yoshihiro; Iwata, Hiromi; Endo, Rika; Itoh, Toshimasa; Shiokawa, Mitsuru; Shibasaki, Yumiko; Nakamura, Masumi; Hisada, Atsuo; Sano, Motohiko; Kokubun, Hideya; Kagaya, Hajime; Suzuki, Tsutomu

    2008-05-01

    To examine the influence of drug therapy guidance by pharmacists on the use of a rescue dose (RD) for opioid analgesics (opioids) and pain as well as drug therapy guidance in cancer pain treatment, we conducted a patient satisfaction survey. The subjects were 56 cancer patients undergoing opioid therapy in hospitals belonging to the Symptom Control Research Group (SCORE-G). The survey period was 2 months (from November 1 until December 31, 2006). Drug therapy guidance regarding the use of RD was performed twice in each patient to evaluate the patients' satisfaction. RD was prescribed in 87.8% of the patients in the first guidance and in 80.5% in the second guidance periods. The proportion of patients who used RD significantly increased from 63.8% to 87.5%. Five items significantly improved in the second guidance period: "marked analgesic effects," "satisfaction with current treatment," "correct understanding of RD usage," "relief through RD," and "appropriate use of RD." On comprehensive evaluation following the second round of guidance, 81% of the patients reported overall satisfaction, and 78% reported the usefulness of guidance in pain treatment. These results suggest that positive guidance by pharmacists increases patients' satisfaction. In providing guidance, it was important to confirm the characteristics and side effects of opioids as well as the necessity of RD to patients accurately and repeatedly.

  13. Chapter 4. Monitoring vegetation composition and structure as habitat attributes

    Science.gov (United States)

    Thomas E. DeMeo; Mary M. Manning; Mary M. Rowland; Christina D. Vojta; Kevin S. McKelvey; C. Kenneth Brewer; Rebecca S.H. Kennedy; Paul A. Maus; Bethany Schulz; James A. Westfall; Timothy J. Mersmann

    2013-01-01

    Vegetation composition and structure are key components of wildlife habitat (Mc- Comb et al. 2010, Morrison et al. 2006) and are, therefore, essential components of all wildlife habitat monitoring. The objectives of this chapter are to describe common habitat attributes derived from vegetation composition and structure and to provide guidance for obtaining and using...

  14. FDA 2011 process validation guidance: lifecycle compliance model.

    Science.gov (United States)

    Campbell, Cliff

    2014-01-01

    This article has been written as a contribution to the industry's efforts in migrating from a document-driven to a data-driven compliance mindset. A combination of target product profile, control engineering, and general sum principle techniques is presented as the basis of a simple but scalable lifecycle compliance model in support of modernized process validation. Unit operations and significant variables occupy pole position within the model, documentation requirements being treated as a derivative or consequence of the modeling process. The quality system is repositioned as a subordinate of system quality, this being defined as the integral of related "system qualities". The article represents a structured interpretation of the U.S. Food and Drug Administration's 2011 Guidance for Industry on Process Validation and is based on the author's educational background and his manufacturing/consulting experience in the validation field. The U.S. Food and Drug Administration's Guidance for Industry on Process Validation (2011) provides a wide-ranging and rigorous outline of compliant drug manufacturing requirements relative to its 20(th) century predecessor (1987). Its declared focus is patient safety, and it identifies three inter-related (and obvious) stages of the compliance lifecycle. Firstly, processes must be designed, both from a technical and quality perspective. Secondly, processes must be qualified, providing evidence that the manufacturing facility is fully "roadworthy" and fit for its intended purpose. Thirdly, processes must be verified, meaning that commercial batches must be monitored to ensure that processes remain in a state of control throughout their lifetime.

  15. NCALM's Lessons Learned and Insights into the Future from Ten + Years of Providing Geodetic Images for the monitoring of Hazards and the Response to Disasters

    Science.gov (United States)

    Fernandez Diaz, J. C.; Shrestha, R. L.; Carter, W. E.; Glennie, C. L.; Sartori, M. P.; Singhania, A.

    2012-12-01

    The National Center for Airborne Laser Mapping NCALM was created in 2003 through a grant from and National Science Foundation to support the use of airborne laser swath mapping technology (ALSM aka LiDAR) by the scientific community. NCALM's main goals are to provide research quality airborne LiDAR observations to the scientific community, to advance the state of the art in airborne laser mapping, and to train and educate graduate students with knowledge of airborne mapping to meet the needs of private industry, government agencies and academic institutions. Even before its creation, NCALM researchers had been exploring the application of LiDAR technologies for the monitoring of Geohazards and the response and recovery from man-made and natural disasters. Some of these applications include: mapping debris caused by the 11 September 2001 terrorist attacks in New York; mapping thousands of km of faults along the Pacific coast of the US extending from Southern California to Alaska, through the OSU/USGS B4 and UNAVCO EarthScope projects; mapping of lava fields in Hawaii; mapping post-forest-fire zones in the San Gabriel Mountains, CA and Valles Caldera, NM; mapping beach erosion/deposition induced by hurricanes along the Panhandle and Atlantic coasts of Florida; rapid-response mapping of the Iowa river floods in 2008 and the El Mayor - Cucapah Earthquake in 2010. The experience gained and lessons learned by NCALM regarding the long term monitoring of hazards for the preparation, response and recovery of disasters range from navigating the regulatory and logistic challenges of being present in a disaster area, to the production of real-time geodetic imagery and data for support of the authorities, to performing change detection (surface deformation, sediment transport, infrastructure damage) using LiDAR data products obtained by different vendors, with different equipment and operated under different specifications. End users of the information uniquely provided by

  16. Automatic guidance and control laws for helicopter obstacle avoidance

    Science.gov (United States)

    Cheng, Victor H. L.; Lam, T.

    1992-01-01

    The authors describe the implementation of a full-function guidance and control system for automatic obstacle avoidance in helicopter nap-of-the-earth (NOE) flight. The guidance function assumes that the helicopter is sufficiently responsive so that the flight path can be readily adjusted at NOE speeds. The controller, basically an autopilot for following the derived flight path, was implemented with parameter values to control a generic helicopter model used in the simulation. Evaluation of the guidance and control system with a 3-dimensional graphical helicopter simulation suggests that the guidance has the potential for providing good and meaningful flight trajectories.

  17. A Formal Investigation of the Organization of Guidance Behavior: Implications for Humans and Autonomous Guidance

    Science.gov (United States)

    Kong, Zhaodan

    Guidance behavior generated either by artificial agents or humans has been actively studied in the fields of both robotics and cognitive science. The goals of these two fields are different. The former is the automatic generation of appropriate or even optimal behavior, while the latter is the understanding of the underlying mechanism. Their challenges, though, are closely related, the most important one being the lack of a unified, formal and grounded framework where the guidance behavior can be modeled and studied. This dissertation presents such a framework. In this framework, guidance behavior is analyzed as the closed-loop dynamics of the whole agent-environment system. The resulting dynamics give rise to interaction patterns. The central points of this dissertation are that: first of all, these patterns, which can be explained in terms of symmetries that are inherent to the guidance behavior, provide building blocks for the organization of behavior; second, the existence of these patterns and humans' organization of their guidance behavior based on these patterns are the reasons that humans can generate successful behavior in spite of all the complexities involved in the planning and control. This dissertation first gives an overview of the challenges existing in both scientific endeavors, such as human and animal spatial behavior study, and engineering endeavors, such as autonomous guidance system design. It then lays out the foundation for our formal framework, which states that guidance behavior should be interpreted as the collection of the closed-loop dynamics resulting from the agent's interaction with the environment. The following, illustrated by examples of three different UAVs, shows that the study of the closed-loop dynamics should not be done without the consideration of vehicle dynamics, as is the common practice in some of the studies in both autonomous guidance and human behavior analysis. The framework, the core concepts of which are

  18. Safety of magnetic fusion facilities: Guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    This document provides guidance for the implementation of the requirements identified in DOE-STD-6002-96, Safety of Magnetic Fusion Facilities: Requirements. This guidance is intended for the managers, designers, operators, and other personnel with safety responsibilities for facilities designated as magnetic fusion facilities. While the requirements in DOE-STD-6002-96 are generally applicable to a wide range of fusion facilities, this Standard, DOE-STD-6003-96, is concerned mainly with the implementation of those requirements in large facilities such as the International Thermonuclear Experimental Reactor (ITER). Using a risk-based prioritization, the concepts presented here may also be applied to other magnetic fusion facilities. This Standard is oriented toward regulation in the Department of Energy (DOE) environment as opposed to regulation by other regulatory agencies. As the need for guidance involving other types of fusion facilities or other regulatory environments emerges, additional guidance volumes should be prepared. The concepts, processes, and recommendations set forth here are for guidance only. They will contribute to safety at magnetic fusion facilities.

  19. Research Circles - a method for developing guidance practices

    DEFF Research Database (Denmark)

    2012-01-01

    This video reports on our work with using research circles to improve our understanding of how to provide guidance and counseling to help young people in danger of dropping out of school. The video is based on the paper: Research Circles -- a method for developing guidance practices...

  20. The history and future of dietary guidance in America

    Science.gov (United States)

    LAY ABSTRACT The United States has a 100-year history of providing dietary guidance to Americans. This review describes the development and significance of dietary guidance in the US, including the Dietary Guidelines for Americans, and emphasizes the foundations upon which they were developed, the ...

  1. Meta-Narrative on Guidance and Counselling in Schools

    Science.gov (United States)

    Thamarasseri, Ismail

    2014-01-01

    The purposes of guidance and counselling provide emphasis and strength to the educational program. The major goals of counselling are to promote personal growth and to prepare students to become motivated workers and responsible citizens. The chief aim of an educational guidance is to develop the ability of co-ordinating with the school…

  2. An Evaluation of Guidance and Counselling Services Offered to ...

    African Journals Online (AJOL)

    This paper sought to evaluate the guidance and counselling services offered to students in Gwanda urban and peri-urban secondary schools. Guidance and counselling is regarded as a programme and service in the education system, providing advice with regards to students' education, career planning, social issues or ...

  3. Factors affecting guidance and counseling programme in primary ...

    African Journals Online (AJOL)

    Too, it was found that teachers' attitudes, training in counselling, availability of time and facilities have a negative impact on the guidance and counselling programme. The Government and the schools' management do not provide the needed infrastructure for guidance and counseling. It was recommended that training of ...

  4. PSD Increment Consumption Guidance

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  5. Global guidance on environmental life cycle impact assessment indicators: Progress and case study

    DEFF Research Database (Denmark)

    Frischknecht, Rolf; Fantke, Peter; Tschümperlin, Laura

    2016-01-01

    Purpose The life cycle impact assessment (LCIA) guidance flagship project of the United Nations Environment Programme (UNEP)/Society of Environmental Toxicology and Chemistry (SETAC) Life Cycle Initiative aims at providing global guidance and building scientific consensus on environmental LCIA...

  6. NAFTA Guidance on Data Requirements for Pesticide Import Tolerances: Questions & Answers

    Science.gov (United States)

    These Qs&As provide details of implementation related to a guidance document describing the data requirements for establishing pesticide import tolerances in Canada and the United States: NAFTA Guidance on Data Requirements for Pesticide Import Tolerances.

  7. Applying human rights to maternal health: UN Technical Guidance on rights-based approaches.

    Science.gov (United States)

    Yamin, Alicia Ely

    2013-05-01

    In the last few years there have been several critical milestones in acknowledging the centrality of human rights to sustainably addressing the scourge of maternal death and morbidity around the world, including from the United Nations Human Rights Council. In 2012, the Council adopted a resolution welcoming a Technical Guidance on rights-based approaches to maternal mortality and morbidity, and calling for a report on its implementation in 2 years. The present paper provides an overview of the contents and significance of the Guidance. It reviews how the Guidance can assist policymakers in improving women's health and their enjoyment of rights by setting out the implications of adopting a human rights-based approach at each step of the policy cycle, from planning and budgeting, to ensuring implementation, to monitoring and evaluation, to fostering accountability mechanisms. The Guidance should also prove useful to clinicians in understanding rights frameworks as applied to maternal health. Copyright © 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  8. Year-Long Monitoring of Physico-Chemical and Biological Variables Provide a Comparative Baseline of Coral Reef Functioning in the Central Red Sea.

    Directory of Open Access Journals (Sweden)

    Anna Roik

    Full Text Available Coral reefs in the central Red Sea are sparsely studied and in situ data on physico-chemical and key biotic variables that provide an important comparative baseline are missing. To address this gap, we simultaneously monitored three reefs along a cross-shelf gradient for an entire year over four seasons, collecting data on currents, temperature, salinity, dissolved oxygen (DO, chlorophyll-a, turbidity, inorganic nutrients, sedimentation, bacterial communities of reef water, and bacterial and algal composition of epilithic biofilms. Summer temperature (29-33°C and salinity (39 PSU exceeded average global maxima for coral reefs, whereas DO concentration was low (2-4 mg L-1. While temperature and salinity differences were most pronounced between seasons, DO, chlorophyll-a, turbidity, and sedimentation varied most between reefs. Similarly, biotic communities were highly dynamic between reefs and seasons. Differences in bacterial biofilms were driven by four abundant families: Rhodobacteraceae, Flavobacteriaceae, Flammeovirgaceae, and Pseudanabaenaceae. In algal biofilms, green crusts, brown crusts, and crustose coralline algae were most abundant and accounted for most of the variability of the communities. Higher bacterial diversity of biofilms coincided with increased algal cover during spring and summer. By employing multivariate matching, we identified temperature, salinity, DO, and chlorophyll-a as the main contributing physico-chemical drivers of biotic community structures. These parameters are forecast to change most with the progression of ocean warming and increased nutrient input, which suggests an effect on the recruitment of Red Sea benthic communities as a result of climate change and anthropogenic influence. In conclusion, our study provides insight into coral reef functioning in the Red Sea and a comparative baseline to support coral reef studies in the region.

  9. Year-Long Monitoring of Physico-Chemical and Biological Variables Provide a Comparative Baseline of Coral Reef Functioning in the Central Red Sea

    KAUST Repository

    Roik, Anna Krystyna

    2016-11-09

    Coral reefs in the central Red Sea are sparsely studied and in situ data on physico-chemical and key biotic variables that provide an important comparative baseline are missing. To address this gap, we simultaneously monitored three reefs along a cross-shelf gradient for an entire year over four seasons, collecting data on currents, temperature, salinity, dissolved oxygen (DO), chlorophyll-a, turbidity, inorganic nutrients, sedimentation, bacterial communities of reef water, and bacterial and algal composition of epilithic biofilms. Summer temperature (29–33°C) and salinity (39 PSU) exceeded average global maxima for coral reefs, whereas DO concentration was low (2–4 mg L-1). While temperature and salinity differences were most pronounced between seasons, DO, chlorophyll-a, turbidity, and sedimentation varied most between reefs. Similarly, biotic communities were highly dynamic between reefs and seasons. Differences in bacterial biofilms were driven by four abundant families: Rhodobacteraceae, Flavobacteriaceae, Flammeovirgaceae, and Pseudanabaenaceae. In algal biofilms, green crusts, brown crusts, and crustose coralline algae were most abundant and accounted for most of the variability of the communities. Higher bacterial diversity of biofilms coincided with increased algal cover during spring and summer. By employing multivariate matching, we identified temperature, salinity, DO, and chlorophyll-a as the main contributing physico-chemical drivers of biotic community structures. These parameters are forecast to change most with the progression of ocean warming and increased nutrient input, which suggests an effect on the recruitment of Red Sea benthic communities as a result of climate change and anthropogenic influence. In conclusion, our study provides insight into coral reef functioning in the Red Sea and a comparative baseline to support coral reef studies in the region.

  10. Geometry can provide long-range mechanical guidance for embryogenesis.

    Directory of Open Access Journals (Sweden)

    Mahamar Dicko

    2017-03-01

    Full Text Available Downstream of gene expression, effectors such as the actomyosin contractile machinery drive embryo morphogenesis. During Drosophila embryonic axis extension, actomyosin has a specific planar-polarised organisation, which is responsible for oriented cell intercalation. In addition to these cell rearrangements, cell shape changes also contribute to tissue deformation. While cell-autonomous dynamics are well described, understanding the tissue-scale behaviour challenges us to solve the corresponding mechanical problem at the scale of the whole embryo, since mechanical resistance of all neighbouring epithelia will feedback on individual cells. Here we propose a novel numerical approach to compute the whole-embryo dynamics of the actomyosin-rich apical epithelial surface. We input in the model specific patterns of actomyosin contractility, such as the planar-polarisation of actomyosin in defined ventro-lateral regions of the embryo. Tissue strain rates and displacements are then predicted over the whole embryo surface according to the global balance of stresses and the material behaviour of the epithelium. Epithelia are modelled using a rheological law that relates the rate of deformation to the local stresses and actomyosin anisotropic contractility. Predicted flow patterns are consistent with the cell flows observed when imaging Drosophila axis extension in toto, using light sheet microscopy. The agreement between model and experimental data indicates that the anisotropic contractility of planar-polarised actomyosin in the ventro-lateral germband tissue can directly cause the tissue-scale deformations of the whole embryo. The three-dimensional mechanical balance is dependent on the geometry of the embryo, whose curved surface is taken into account in the simulations. Importantly, we find that to reproduce experimental flows, the model requires the presence of the cephalic furrow, a fold located anteriorly of the extending tissues. The presence of this geometric feature, through the global mechanical balance, guides the flow and orients extension towards the posterior end.

  11. Providing varying degrees of guidance for Work-Integrated Learning

    NARCIS (Netherlands)

    Lindstaedt, S.N.; Kump, B.; Beham, G.; Pammer, V.; Ley, T.; Dotan, A.; de Hoog, Robert; Wolpers, M.; Kirschner, P.A.; Scheffel, M.; Lindstaedt, S.; Dimitrova, V.

    2010-01-01

    We present a work-integrated learning (WIL) concept which aims at empowering employees to learn while performing their work tasks. Within three usage scenarios we introduce the APOSDLE environment which embodies the WIL concept and helps knowledge workers move fluidly along the whole spectrum of WIL

  12. EuroEco (European Health Economic Trial on Home Monitoring in ICD Patients): a provider perspective in five European countries on costs and net financial impact of follow-up with or without remote monitoring.

    Science.gov (United States)

    Heidbuchel, Hein; Hindricks, Gerd; Broadhurst, Paul; Van Erven, Lieselot; Fernandez-Lozano, Ignacio; Rivero-Ayerza, Maximo; Malinowski, Klaus; Marek, Andrea; Romero Garrido, Rafael F; Löscher, Steffen; Beeton, Ian; Garcia, Enrique; Cross, Stephen; Vijgen, Johan; Koivisto, Ulla-Maija; Peinado, Rafael; Smala, Antje; Annemans, Lieven

    2015-01-14

    Remote follow-up (FU) of implantable cardiac defibrillators (ICDs) allows for fewer in-office visits in combination with earlier detection of relevant findings. Its implementation requires investment and reorganization of care. Providers (physicians or hospitals) are unsure about the financial impact. The primary end-point of this randomized prospective multicentre health economic trial was the total FU-related cost for providers, comparing Home Monitoring facilitated FU (HM ON) to regular in-office FU (HM OFF) during the first 2 years after ICD implantation. Also the net financial impact on providers (taking national reimbursement into account) and costs from a healthcare payer perspective were evaluated. A total of 312 patients with VVI- or DDD-ICD implants from 17 centres in six EU countries were randomised to HM ON or OFF, of which 303 were eligible for data analysis. For all contacts (in-office, calendar- or alert-triggered web-based review, discussions, calls) time-expenditure was tracked. Country-specific cost parameters were used to convert resource use into monetary values. Remote FU equipment itself was not included in the cost calculations. Given only two patients from Finland (one in each group) a monetary valuation analysis was not performed for Finland. Average age was 62.4 ± 13.1 years, 81% were male, 39% received a DDD system, and 51% had a prophylactic ICD. Resource use with HM ON was clearly different: less FU visits (3.79 ± 1.67 vs. 5.53 ± 2.32; P financial impact on providers [profit of €408 (327-489) vs. €400 (345-455); range for difference (€-104 to 88), NS], but there was heterogeneity among countries, with less profit for providers in the absence of specific remote FU reimbursement (Belgium, Spain, and the Netherlands) and maintained or increased profit in cases where such reimbursement exists (Germany and UK). Quality of life (SF-36) was not different. For all the patients as a whole, FU-related costs for providers are not

  13. Key Performance Indicators for the Assessment of Pediatric Pharmacotherapeutic Guidance

    Science.gov (United States)

    Barrett, Jeffrey S.; Patel, Dimple; Jayaraman, Bhuvana; Narayan, Mahesh; Zuppa, Athena

    2008-01-01

    Given the paucity of actual guidance provided for managing pediatric drug therapy, prescribing caregivers must be able to draw on the limited published information in pediatrics and/or guidance provided in adults with some account for expected pediatric response. Guidance for managing drug therapy in children is clearly desirable. Our objectives were to construct key performance indicators (KPIs) for pediatric pharmacotherapy guidance to identify drugs where pharmacotherapy guidance would be most beneficial. A pilot survey to assess variation in caregiver appreciation for pediatric dosing guidance has also been constructed to provide a complementary subjective assessment. Three KPI categories, drug utilization (based on hospital admission and billing data collected from 2001 through 2006), medical need, and guidance outcome value along with a KPI composite score have been proposed. Low scores are favored with respect to prioritization for pharmacotherapy guidance. The pilot survey consisted of 15 questions to assess 1) physician knowledge regarding dosing guidance, 2) attitudes toward dose modification and patient individualization, 3) the accessibility, ease of use and appropriateness of existing data stores, and 4) frequency of dosing modification, consultation of dosing compendiums and estimate of success rate in dosing guidance. Pilot results suggest that dosing guidance is generally viewed as important and that the existing resources are insufficient to guide recommendations for all drugs. While the majority of respondents check more than one resource less than 25% of the time, at least 25% of the respondents check more than one resource 25–50% of the time. The majority viewed the relevance of dosing guidance very important to the management of drug therapy. The questionnaire is being extended to the primary care centers, the Kids First Network and specialty care centers. Results will guide the development of decision support systems (DSS) that provide

  14. EarthScope's Plate Boundary Observatory in Alaska: Building on Existing Infrastructure to Provide a Platform for Integrated Research and Hazard-monitoring Efforts

    Science.gov (United States)

    Boyce, E. S.; Bierma, R. M.; Willoughby, H.; Feaux, K.; Mattioli, G. S.; Enders, M.; Busby, R. W.

    2014-12-01

    EarthScope's geodetic component in Alaska, the UNAVCO-operated Plate Boundary Observatory (PBO) network, includes 139 continuous GPS sites and 41 supporting telemetry relays. These are spread across a vast area, from northern AK to the Aleutians. Forty-five of these stations were installed or have been upgraded in cooperation with various partner agencies and currently provide data collection and transmission for more than one group. Leveraging existing infrastructure normally has multiple benefits, such as easier permitting requirements and costs savings through reduced overall construction and maintenance expenses. At some sites, PBO-AK power and communications systems have additional capacity beyond that which is needed for reliable acquisition of GPS data. Where permits allow, such stations could serve as platforms for additional instrumentation or real-time observing needs. With the expansion of the Transportable Array (TA) into Alaska, there is increased interest to leverage existing EarthScope resources for station co-location and telemetry integration. Because of the complexity and difficulty of long-term O&M at PBO sites, however, actual integration of GPS and seismic equipment must be considered on a case-by-case basis. UNAVCO currently operates two integrated GPS/seismic stations in collaboration with the Alaska Earthquake Center, and three with the Alaska Volcano Observatory. By the end of 2014, PBO and TA plan to install another four integrated and/or co-located geodetic and seismic systems. While three of these are designed around existing PBO stations, one will be a completely new TA installation, providing PBO with an opportunity to expand geodetic data collection in Alaska within the limited operations and maintenance phase of the project. We will present some of the design considerations, outcomes, and lessons learned from past and ongoing projects to integrate seismometers and other instrumentation at PBO-Alaska stations. Developing the PBO

  15. Automated Guidance for Student Inquiry

    Science.gov (United States)

    Gerard, Libby F.; Ryoo, Kihyun; McElhaney, Kevin W.; Liu, Ou Lydia; Rafferty, Anna N.; Linn, Marcia C.

    2016-01-01

    In 4 classroom experiments we investigated uses for technologies that automatically score student generated essays, concept diagrams, and drawings in inquiry curricula. We used the automatic scores to assign typical and research-based guidance and studied the impact of the guidance on student progress. Seven teachers and their 897 students…

  16. GUIDANCE DOCUMENT ON IMPLEMENTATION OF THE ...

    Science.gov (United States)

    The Agreement in Principle for the Stage 2 M-DBP Federal Advisory Committee contains a list of treatment processes and management practices for water systems to use in meeting additional Cryptosporidium treatment requirements under the LT2ESWTR. This list, termed the microbial toolbox, includes watershed control programs, alternative intake locations, pretreatment processes, additional filtration barriers, inactivation technologies, and enhanced plant performance. The intent of the microbial toolbox is to provide water systems with broad flexibility in selecting cost-effective LT2ESWTR compliance strategies. Moreover, the toolbox allows systems that currently provide additional pathogen barriers or that can demonstrate enhanced performance to receive additional Cryptosporidium treatment credit. Provide guidance to utilities with surface water supplies and to state drinking water programs on the use of different treatment technologies to reduce the level of Cryptosporidium in drinking water. Technologies included in the guidance manual may be used to achieve compliance with the requirements of the LT2ESWTR.

  17. 77 FR 5415 - National Organic Program: Notice of Draft Guidance for Accredited Certifying Agents, Certified...

    Science.gov (United States)

    2012-02-03

    ...-certified handlers of certified organic products. The draft guidance document is entitled as follows...: Guidance and Instructions for Accredited Certifying Agents (ACAs) and Certified Operations.'' This Handbook provides those who own, manage, or certify organic operations with guidance and instructions that can...

  18. 77 FR 58399 - Draft Guidance for Industry on Bioequivalence Recommendations for Pentosan Polysulfate Sodium...

    Science.gov (United States)

    2012-09-20

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Bioequivalence... recommendations provide specific guidance on the design of bioequivalence (BE) studies to support abbreviated new... regulation (21 CFR 10.115). The draft guidance, when finalized, will represent the Agency's current thinking...

  19. 77 FR 56851 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Science.gov (United States)

    2012-09-14

    ... HUMAN SERVICES Food and Drug Administration Draft and Revised Draft Guidances for Industry Describing... provide product-specific guidance on the design of BE studies to support abbreviated new drug applications... practices regulation (21 CFR 10.115). These guidances represent the Agency's current thinking on product...

  20. NRC ARDC Guidance Support Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Holbrook, Mark R. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-07-01

    This report provides a summary that reflects the progress and status of proposed regulatory design criteria for advanced non-light water reactor (LWR) designs in accordance with the Level 3 milestone M3AT-17IN2001013 in work package AT-17IN200101. These criteria have been designated as advanced reactor design criteria (ARDC) and they provide guidance to future applicants for addressing the general design criteria (GDC) that are currently applied specifically to LWR designs. This report provides a summary of Phase 2 activities related to the various tasks associated with ARDC development and the subsequent development of ARDC regulatory guidance for sodium fast reactor (SFR) and modular high-temperature gas-cooled reactor (HTGR) designs. Status Report Organization: Section 2 discusses the origin of the GDC and their application to LWRs. Section 3 addresses the objective of this initiative and how it benefits the advanced non-LWR reactor vendors. Section 4 discusses the scope and structure of the initiative. Section 5 provides background on the U.S. Department of Energy (DOE) ARDC team’s original development of the proposed ARDC that were submitted to the NRC for consideration. Section 6 provides a summary of recent ARDC Phase 2 activities. Appendices A through E document the DOE ARDC team’s public comments on various sections of the NRC’s draft regulatory guide DG–1330, “Guidance for Developing Principal Design Criteria for Non-Light Water Reactors.”

  1. Stressor Identification Guidance Document | Science Inventory ...

    Science.gov (United States)

    EPA has made availabile the Stressor Identification Guidance Document (EPA 822-B-00-025) published under the authority of Section 304(a)(2) of the Clean Water Act (CWA). This technical guidance document is designed to assist water quality managers in identifying unknown causes of biological impairments in any type of water body. Section 101(a) of the Clean Water Act states that it is the objective of the Act to restore and maintain the chemical, physical and biological integrity of the Nation's waters. To achieve this objective, numerous States and Tribes are using biological assessments and biocriteria to help protect the Nation's waters. Using these tools, State and Tribal water quality experts are finding water bodies where the fish, invertebrate, algae or plant communities (or other aquatic life) have been detrimentally impacted by different singular or multiple causes. In many cases, the cause, or causes, of these biological impairments have not yet been identified. The Stressor Identification Guidance Document provides a logical, scientific process by which State, Tribal, and other water quality experts can evaluate available information to identify the stressor(s) causing the biological impairments. The process has three main steps: (1) List candidate causes of impairment, (2) analyze the evidence, and (3) characterize the causes. When evidence is adequate, using this guidance, investigators should be able to successfully identify the likely cause, or ca

  2. 77 FR 59000 - Guidance for Industry: Pre-Storage Leukocyte Reduction of Whole Blood and Blood Components...

    Science.gov (United States)

    2012-09-25

    ... Whole Blood and Blood Components Intended for Transfusion; Availability AGENCY: Food and Drug... and Blood Components Intended for Transfusion'' dated September 2012. The guidance document provides... Blood Components Intended for Transfusion'' dated September 2012. The guidance document provides blood...

  3. Federal Guidance Report No. 10: The Radioactivity Concentration Guides

    Science.gov (United States)

    This document provides the calculation of derived limits for the 1960 Radiation Protection Guides reflecting updated models for dosimetry and biological transport. This report has been superseded by Federal Guidance Report No. 11.

  4. Grants Management Guidance for Non-Profit Organizations

    Science.gov (United States)

    This guidance is intended to provide non-profit grant recipients with information to ensure that their organizations remain in compliance with the Code of Federal Regulations (CFR), Office of Management (OMB) cost principles, and the terms and conditions.

  5. Acoustic Communication for High-Doppler Guidance and Control

    National Research Council Canada - National Science Library

    Freitag, Lee

    2002-01-01

    The long-term goal of this program is to provide an acoustic communications system suitable for multiple fast-moving platforms to support the guidance and control function of current and future weapons (Figure 1...

  6. Sliding mode predictive guidance for terminal rendezvous in eccentric orbits

    Science.gov (United States)

    Kasaeian, Seyed Aliakbar; Assadian, Nima; Ebrahimi, Masoud

    2017-11-01

    This paper presents a robust guidance algorithm for a chaser spacecraft to rendezvous with a target spacecraft in Earth orbit. The basis of the proposed guidance method is finding an appropriate set of states as close as possible to the current states that would lead the spacecraft to the target in the desired mission time. In order to provide the prediction of states, the relative dynamics equations of motion are solved analytically for the chaser spacecraft rendezvous considering constant acceleration. Although the equations are solved for rendezvous with circular orbit target, it is shown by several simulations that the proposed guidance algorithm is applicable in perturbed elliptical orbits rendezvous as well. The sliding mode method as a robust nonlinear method is utilized as the steering law. The robust steering law tracks the desired states computed by the predictive guidance method. The Lyapunov stability method proves the asymptotic stability of the integrated guidance and steering laws. Because the proposed closed-loop guidance is simple and computationally easy, it is suitable for implementation in real-time applications. Some numerical simulations are conducted to show the performance of the proposed guidance method in different conditions. It is illustrated that compared with other steering laws, the fuel consumption is reduced utilizing the proposed guidance approach. The results reveal that the sliding mode guarantees the tracking of the required states and minimum final errors even in the presence of uncertainties and disturbances.

  7. Industrial wind turbine post-construction bird and bat monitoring: A policy framework for Canada.

    Science.gov (United States)

    Parisé, Jason; Walker, Tony R

    2017-10-01

    Electricity generation from wind energy has proliferated throughout North America and will continue to grow. Given Canada's expected increase in wind energy capacity, consideration of the potential adverse impacts to bird and bat populations is prudent given their sensitivity to these projects. The province of Ontario, Canada is currently the leading jurisdiction for wind energy development, and for provincial guidance on pre- and post-construction monitoring. With uniform monitoring guidance in Ontario, wind energy proponents, and third-party consultants, have developed post-construction monitoring protocols that meet provincial guidance, while also providing standardized reporting. In Atlantic Canada, post-construction guidelines vary between provinces, depending mostly on guidance from the Environment Canada Canadian Wildlife Service and relevant provincial agencies. To ensure quality post-construction monitoring results in Atlantic Canada and other provinces, it is imperative that all Canadian provinces adopt similar approaches to those employed in Ontario. This paper reviews major causes of bird and bat mortalities; reviews Canadian federal and Ontario provincial bird and bat monitoring guidelines to elucidate gaps between environmental assessment (EA) theory and application; summarizes post-construction monitoring protocols from eight bird and bat post-construction monitoring programs used in Ontario; and, proposes recommendations to support future wind development opportunities across Canada and specifically in Atlantic Canada. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Image guidance and neuromonitoring in neurosurgery.

    Science.gov (United States)

    Ng, Wai Hoe; Mukhida, Karim; Rutka, James T

    2010-04-01

    The localization of tumors and epileptogenic foci within the somatosensory or language cortex of the brain of a child poses unique neurosurgical challenges. In the past, lesions in these regions were not treated aggressively for fear of inducing neurological deficits. As a result, while function may have been preserved, the underlying disease may not have been optimally treated, and repeat neurosurgical procedures were frequently required. Today, with the advent of preoperative brain mapping, image guidance or neuronavigation, and intraoperative monitoring, peri-Rolandic and language cortex lesions can be approached directly and definitively with a high degree of confidence that neurosurgical function will be maintained. The preoperative brain maps can now be achieved with magnetic resonance imaging (MRI), functional MRI, magnetoencephalography, and diffusion tensor imaging. Image guidance systems have improved significantly and include the use of the intraoperative MRI. Somatosensory, motor, and brainstem auditory-evoked potentials are used as standard neuromonitoring techniques in many centers around the world. Added to this now is the use of continuous train-of-five monitoring of the integrity of the corticospinal tract while operating in the peri-Rolandic region. We are in an era where continued advancements can be expected in mapping additional pathways such as visual, memory, and hearing pathways. With these new advances, neurosurgeons can expect to significantly improve their surgical outcomes further.

  9. Guidance at the educational marketplace

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    in educational policies and institutions. As educational systems have expanded and, further, have been restructured with the expansion of choice opportunities since the 1980s, guidance has become prioritized as a form of counseling or coaching, which can support students. Thus, guidance has become an important...... `agent´ on the educational "market´, assisting (potential) students into and around the `marketplace´. Consequently, guidance is also an important `agent´ for educational institutions that increasingly use marketing strategies to promote themselves on the market to attract and hold on to their “customers......” in order for the institutions to increase their ´market value´, `sales” and “turnover”. Thus, the expansion of guidance is nurtured by the expansion of the logic of marketization and consumerism. Drawing on Foucauldian perspectives in educational research, which highlight the expansion of powerful...

  10. SPLC Sustainable Purchasing Guidance Profile

    Science.gov (United States)

    To help you find the resource that is right for your organization, EPA conducted a scan of the landscape and developed summary profiles of some of the leading sources of sustainable purchasing guidance around the globe.

  11. Response to work activity guidance

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This memorandum is concerning the request from the FY95 Platte-Kansas Rivers Ecosystem Work Activity Guidance for refuge managers to review the purposes of refuges...

  12. Guidance on Dependence Assessment in SPAR-H

    Energy Technology Data Exchange (ETDEWEB)

    April M. Whaley

    2012-06-01

    As part of the effort to develop the SPAR-H user guidance, particular attention was paid to the assessment of dependence in order to address user questions about proper application of dependence. This paper presents a discussion of dependence from a psychological perspective and provides guidance on applying this information during the qualitative analysis of dependence to ensure more realistic and appropriate dependence assessments with the SPAR-H method. While this guidance was developed with SPAR-H in mind, it may be informative to other human reliability analysis methods that also use a THERP-based dependence approach, particularly if applied at the human failure event level.

  13. Dissecting Attending Surgeons' Operating Room Guidance: Factors That Affect Guidance Decision Making.

    Science.gov (United States)

    Chen, Xiaodong Phoenix; Williams, Reed G; Smink, Douglas S

    2015-01-01

    The amount of guidance provided by the attending surgeon in the operating room (OR) is a key element in developing residents' autonomy. The purpose of this study is to explore factors that affect attending surgeons' decision making regarding OR guidance provided to the resident. We used video-stimulated recall interviews (VSRI) throughout this 2-phase study. In Phase 1, 3 attending surgeons were invited to review separately 30 to 45 minute video segments of their prerecorded surgical operations to explore factors that influenced their OR guidance decision making. In Phase 2, 3 attending surgeons were observed and documented in the OR (4 operations, 341min). Each operating surgeon reviewed their videotaped surgical performance within 5 days of the operation to reflect on factors that affected their decision making during the targeted guidance events. All VSRI were recorded. Thematic analysis and manual coding were used to synthesize and analyze data from VSRI transcripts, OR observation documents, and field notes. A total of 255 minutes of VSRI involving 6 surgeons and 7 surgical operations from 5 different procedures were conducted. A total of 13 guidance decision-making influence factors from 4 categories were identified (Cohen's κ = 0.674): Setting (case schedule and patient morbidity), content (procedure attributes and case progress), resident (current competency level, trustworthiness, self-confidence, and personal traits), and attending surgeon (level of experience, level of comfort, preferred surgical technique, OR training philosophy, and responsibility as surgeon). A total of 5 factors (case schedule, patient morbidity, procedure attributes, resident current competency level, and trustworthiness) influenced attending surgeons' pre-OR guidance plans. "OR training philosophy" and "responsibility as surgeon" were anchor factors that affected attending surgeons' OR guidance decision-making patterns. Surgeons' OR guidance decision making is a dynamic process

  14. Viscoelastic guidance of resuscitation

    DEFF Research Database (Denmark)

    Stensballe, Jakob; Ostrowski, Sisse R; Johansson, Pär I

    2014-01-01

    PURPOSE OF REVIEW: Bleeding in trauma carries a high mortality and is increased in case of coagulopathy. Our understanding of hemostasis and coagulopathy has improved, leading to a change in the protocols for hemostatic monitoring. This review describes the current state of evidence supporting...... populations. In trauma care, viscoelastic hemostatic assays allows for rapid and timely identification of coagulopathy and individualized, goal-directed transfusion therapy. As part of the resuscitation concept, viscoelastic hemostatic assays seem to improve outcome also in trauma; however, there is a need...

  15. LiST modelling with monitoring data to estimate impact on child mortality of an ORS and zinc programme with public sector providers in Bihar, India.

    Science.gov (United States)

    Ayyanat, Jayachandran A; Harbour, Catherine; Kumar, Sanjeev; Singh, Manjula

    2018-01-05

    Many interventions have attempted to increase vulnerable and remote populations' access to ORS and zinc to reduce child mortality from diarrhoea. However, the impact of these interventions is difficult to measure. From 2010 to 15, Micronutrient Initiative (MI), worked with the public sector in Bihar, India to enable community health workers to treat and report uncomplicated child diarrhoea with ORS and zinc. We describe how we estimated programme's impact on child mortality with Lives Saved Tool (LiST) modelling and data from MI's management information system (MIS). This study demonstrates that using LiST modelling and MIS data are viable options for evaluating programmes to reduce child mortality. We used MI's programme monitoring data to estimate coverage rates and LiST modelling software to estimate programme impact on child mortality. Four scenarios estimated the effects of different rates of programme scale-up and programme coverage on estimated child mortality by measuring children's lives saved. The programme saved an estimated 806-975 children under-5 who had diarrhoea during five-year project phase. Increasing ORS and zinc coverage rates to 19.8% & 18.3% respectively under public sector coverage with effective treatment would have increased the programme's impact on child mortality and could have achieved the project goal of saving 4200 children's lives during the five-year programme. Programme monitoring data can be used with LiST modelling software to estimate coverage rates and programme impact on child mortality. This modelling approach may cost less and yield estimates sooner than directly measuring programme impact with population-based surveys. However, users must be cautious about relying on modelled estimates of impact and ensure that the programme monitoring data used is complete and precise about the programme aspects that are modelled. Otherwise, LiST may mis-estimate impact on child mortality. Further, LiST software may require modifications

  16. Recommendations for standards of monitoring during anaesthesia and recovery 2015: Association of Anaesthetists of Great Britain and Ireland.

    Science.gov (United States)

    Checketts, M R; Alladi, R; Ferguson, K; Gemmell, L; Handy, J M; Klein, A A; Love, N J; Misra, U; Morris, C; Nathanson, M H; Rodney, G E; Verma, R; Pandit, J J

    2016-01-01

    This guideline updates and replaces the 4th edition of the AAGBI Standards of Monitoring published in 2007. The aim of this document is to provide guidance on the minimum standards for physiological monitoring of any patient undergoing anaesthesia or sedation under the care of an anaesthetist. The recommendations are primarily aimed at anaesthetists practising in the United Kingdom and Ireland. Minimum standards for monitoring patients during anaesthesia and in the recovery phase are included. There is also guidance on monitoring patients undergoing sedation and also during transfer of anaesthetised or sedated patients. There are new sections discussing the role of monitoring depth of anaesthesia, neuromuscular blockade and cardiac output. The indications for end-tidal carbon dioxide monitoring have been updated. © 2015 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists of Great Britain and Ireland.

  17. 21 CFR 601.29 - Guidance documents.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Guidance documents. 601.29 Section 601.29 Food and... LICENSING Biologics Licensing § 601.29 Guidance documents. (a) FDA has made available guidance documents... for Biologics Evaluation and Research (CBER) maintains a list of guidance documents that apply to the...

  18. On information-provided monitoring of geodynamic processes in the Kuznetsk Coal Basin in the conditions of highly intensive sub-soil usage

    Energy Technology Data Exchange (ETDEWEB)

    Oparin, V.N.; Potapov, V.P.; Tanaino, A.S. [Russian Academy of Science, Novosibirsk (Russian Federation). Inst. of Mining

    2006-09-15

    It is shown that formation of underground hollows of the Kuznetsk Coal Basin (Kuzbass), induced by opencut and underground mining has reached an intensity of 1.3-1.5 million m{sup 3}/day. In the conditions of high concentration of mines and open-cuts in small areas, a regional monitoring network is required in view of a generated geomechanical space, hazardous in geodynamic manifestations. A developed information support of this network is presented, including information models of a geological environment and database obtained from instrumental observations on geomechanical processes. The equations of connection between structural and strength characteristics of rocks, their metamorphization grade and occurrence depth are given for five geological-tectonic zones of the Kuzbass as a way of prediction of their properties.

  19. Energy Efficiency/Renewable Energy Programs in State Implementation Plans - Guidance Documents

    Science.gov (United States)

    final document that provides guidance to States and local areas on quantifying and including emission reductions from energy efficiency and renewable energy measures in State Implementation Plans (SIPS).

  20. Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol

    Science.gov (United States)

    2012-01-01

    Background The benefit of self-monitoring of blood glucose (SMBG) in people with type 2 diabetes on diet or oral agents other than sulphonylureas remains uncertain. Trials of interventions incorporating education about self-monitoring of blood glucose have reported mixed results. A recent systematic review concluded that SMBG was not cost-effective. However, what was unclear was whether a cheaper method of self-monitoring (such as urine glucose monitoring) could produce comparable benefit and patient acceptability for less cost. Methods/Design The DESMOND SMBG trial is comparing two monitoring strategies (blood glucose monitoring and urine testing) over 18 months when incorporated into a comprehensive self-management structured education programme. It is a multi-site cluster randomised controlled trial, conducted across 8 sites (7 primary care trusts) in England, UK involving individuals with newly diagnosed Type 2 diabetes. The trial has 80% power to demonstrate equivalence in mean HbA1c (the primary end-point) at 18 months of within ± 0.5% assuming 20% drop out and 20% non-consent. Secondary end-points include blood pressure, lipids, body weight and psychosocial measures as well as a qualitative sub-study. Practices were randomised to one of two arms: participants attend a DESMOND programme incorporating a module on self-monitoring of either urine or blood glucose. The programme is delivered by accredited educators who received specific training about equipoise. Biomedical data are collected and psychosocial scales completed at baseline, and 6, 12, and 18 months post programme. Qualitative research with participants and educators will explore views and experiences of the trial and preferences for methods of monitoring. Discussion The DESMOND SMBG trial is designed to provide evidence to inform the debate about the value of self-monitoring of blood glucose in people with newly diagnosed type 2 diabetes. Strengths include a setting in primary care, a cluster

  1. Accuracy Analysis of Lunar Lander Terminal Guidance Algorithm

    Directory of Open Access Journals (Sweden)

    E. K. Li

    2017-01-01

    Full Text Available This article studies a proposed analytical algorithm of the terminal guidance for the lunar lander. The analytical solution, which forms the basis of the algorithm, was obtained for a constant acceleration trajectory and thrust vector orientation programs that are essentially linear with time. The main feature of the proposed algorithm is a completely analytical solution to provide the lander terminal guidance to the desired spot in 3D space when landing on the atmosphereless body with no numerical procedures. To reach 6 terminal conditions (components of position and velocity vectors at the final time are used 6 guidance law parameters, namely time-to-go, desired value of braking deceleration, initial values of pitch and yaw angles and rates of their change. In accordance with the principle of flexible trajectories, this algorithm assumes the implementation of a regularly updated control program that ensures reaching terminal conditions from the current state that corresponds to the control program update time. The guidance law parameters, which ensure that terminal conditions are reached, are generated as a function of the current phase coordinates of a lander. The article examines an accuracy and reliability of the proposed analytical algorithm that provides the terminal guidance of the lander in 3D space through mathematical modeling of the lander guidance from the circumlunar pre-landing orbit to the desired spot near the lunar surface. A desired terminal position of the lunar lander is specified by the selenographic latitude, longitude and altitude above the lunar surface. The impact of variations in orbital parameters on the terminal guidance accuracy has been studied. By varying the five initial orbit parameters (obliquity, ascending node longitude, argument of periapsis, periapsis height, apoapsis height when the terminal spot is fixed the statistic characteristics of the terminal guidance algorithm error according to the terminal

  2. 2002 WIPP Environmental Monitoring Plan

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2002-09-30

    DOE Order 5400.1, General Environmental Protection Program, requires each DOE | facility to prepare an environmental management plan (EMP). This document is | prepared for WIPP in accordance with the guidance contained in DOE Order 5400.1; DOE Order 5400.5, Radiation Protection of the Public and Environment; applicable sections of Environmental Regulatory Guide for Radiological Effluent Monitoring and Environmental Surveillance (DOE/EH-0173T; DOE, 1991); and the Title 10 Code of Federal Regulations (CFR) Part 834, ''Radiation Protection of the Public and Environment'' (draft). Many sections of DOE Order 5400.1 have been replaced by DOE Order 231.1, which is the driver for the annual Site Environmental Report (SER) and the guidance source for preparing many environmental program documents. The WIPP Project is operated by Westinghouse TRU Solutions (WTS) for the DOE. This plan defines the extent and scope of WIPP's effluent and environmental | monitoring programs during the facility's operational life and also discusses WIPP's quality assurance/quality control (QA/QC) program as it relates to environmental monitoring. In addition, this plan provides a comprehensive description of environmental activities at WIPP including: A summary of environmental programs, including the status of environmental monitoring activities A description of the WIPP Project and its mission A description of the local environment, including demographics An overview of the methodology used to assess radiological consequences to the public, including brief discussions of potential exposure pathways, routine and accidental releases, and their consequences Responses to the requirements described in the Environmental Regulatory Guide for Radiological Effluent Monitoring and Environmental Surveillance.

  3. Autonomous landing guidance system validation

    Science.gov (United States)

    Bui, Long Q.; Franklin, Michael R.; Taylor, Christopher; Neilson, Graham

    1997-06-01

    ALG is a combination of raster imaging sensor, head-up displays, flight guidance and procedures which allow pilots to perform hand flown aircraft maneuvers in adverse weather, at night, or in low visibility conditions at facilities with minimal or no ground aids. Maneuvers in the context of ALG relate to takeoff, landing, rollout, taxi and terminal parking. Commercial needs are driven by potential revenue savings since today only 43 Type III and 80 Type II instrumented landing system (ILS) runway ends in the United States are equipped for lower minimum flight operations. Additionally, most of these ILS facilities are clustered at major gateway airports which further impacts on dispatch authority and general ATC regional delays. Infrastructure consists to upgrade additional runways must not only account for the high integrity ground instrumentation, but also the installation of lights and markers mandated for Cat III operations. The military services ability to train under realistic battlefield conditions, to project power globally in support of national interests, while providing humanitarian aid, is significantly impaired by the inability to conduct precision approaches and landings in low visibility conditions to either instrumented runways or to a more tactical environment with operations into and out of unprepared landing strips, particularly when time does not permit deployment of ground aids and the verification of their integrity. Recently, Lear Astronics, in cooperation with Consortium members of the ALG Program, concluded a flight test program which evaluated the utility of the ALG system in meeting both civil and military needs. Those results are the subject of this paper.

  4. Conceptualizing RTI in 21st-Century Secondary Science Classrooms: Video Games' Potential to Provide Tiered Support and Progress Monitoring for Students with Learning Disabilities

    Science.gov (United States)

    Marino, Matthew T.; Beecher, Constance C.

    2010-01-01

    Secondary schools across the United States are adopting response to intervention (RTI) as a means to identify students with learning disabilities (LD) and provide tiered instructional interventions that benefit all students. The majority of current RTI research focuses on students with reading difficulties in elementary school classrooms.…

  5. Care provided and care setting transitions in the last three months of life of cancer patients: a nationwide monitoring study in four European countries.

    NARCIS (Netherlands)

    Ko, W.; Deliens, L.; Miccinesi, G.; Giusti, F.; Moreels, S.; Donker, G.A.; Owuteaka-Philipsen, B.; Zurriaga, O.; Lopéz-Maside, A.; Block, L. van den

    2014-01-01

    Background: This is an international study across four European countries (Belgium[BE], the Netherlands[NL], Italy[IT] and Spain[ES]) between 2009 and 2011, describing and comparing care and care setting transitions provided in the last three months of life of cancer patients, using representative

  6. Care provided and care setting transitions in the last three months of life of cancer patients: a nationwide monitoring study in four European countries

    NARCIS (Netherlands)

    Ko, W.; Deliens, L.; Miccinesi, G.; Giusti, F.; Moreels, S.; Donker, G.A.; Onwuteaka-Philipsen, B.D.; Zurriaga, O.; Lopez-Maside, A.; Block, L.

    2014-01-01

    Background: This is an international study across four European countries (Belgium[BE], the Netherlands[NL], Italy[IT] and Spain[ES]) between 2009 and 2011, describing and comparing care and care setting transitions provided in the last three months of life of cancer patients, using representative

  7. Shared control of a medical robot with haptic guidance.

    Science.gov (United States)

    Xiong, Linfei; Chng, Chin Boon; Chui, Chee Kong; Yu, Peiwu; Li, Yao

    2017-01-01

    Tele-operation of robotic surgery reduces the radiation exposure during the interventional radiological operations. However, endoscope vision without force feedback on the surgical tool increases the difficulty for precise manipulation and the risk of tissue damage. The shared control of vision and force provides a novel approach of enhanced control with haptic guidance, which could lead to subtle dexterity and better maneuvrability during MIS surgery. The paper provides an innovative shared control method for robotic minimally invasive surgery system, in which vision and haptic feedback are incorporated to provide guidance cues to the clinician during surgery. The incremental potential field (IPF) method is utilized to generate a guidance path based on the anatomy of tissue and surgical tool interaction. Haptic guidance is provided at the master end to assist the clinician during tele-operative surgical robotic task. The approach has been validated with path following and virtual tumor targeting experiments. The experiment results demonstrate that comparing with vision only guidance, the shared control with vision and haptics improved the accuracy and efficiency of surgical robotic manipulation, where the tool-position error distance and execution time are reduced. The validation experiment demonstrates that the shared control approach could help the surgical robot system provide stable assistance and precise performance to execute the designated surgical task. The methodology could also be implemented with other surgical robot with different surgical tools and applications.

  8. Environmental guidance for public participation in environmental restoration activities

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    The US Department of Energy (DOE) is issuing this document, entitled Guidance on Public Participation for US Department of Energy Environmental Restoration Activities, to summarize policy and provide guidance for public participation in environmental restoration activities at DOE Headquarters, Field Offices, facilities, and laboratories. While the Office of Environmental Restoration and Waste Management (EM) has environmental restoration responsibility for the majority of DOE sites and facilities, other DOE Project Offices have similar responsibilities at their sites and facilities. This guidance is applicable to all environment restoration activities conducted by or for DOE under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) as amended by the Superfund Amendments and Reauthorization Act of 1986 (SARA); the Resource Conservation and Recovery Act of 1976 (RCRA) as amended by the Hazardous and Solid Waste Amendments of 1984 (HSWA) (corrective actions only); and the National Environmental Policy Act of 1969 (NEPA). This guidance also is applicable to CERCLA remedial action programs under the Uranium Mill Tailings Radiation Control Act of 1978 and the Formerly Utilized Sites Remedial Action Program, where DOE is the designated lead. The primary objectives of this guidance document are as follows: acclimate DOE staff to a changing culture that emphasizes the importance of public participation activities; provide direction on implementing these public participation activities; and, provide consistent guidance for all DOE Field Offices and facilities. The purpose of this document is to provide guidance on conducting effective public participation activities for environmental restoration activities under CERCLA; RCRA corrective actions under sections 3004(u), 3004(v), and 3008(h); and NEPA public participation activities.

  9. Studies on calibration and validation of data provided by the Global Ozone Monitoring Experiment GOME on ERS-2 (CAVEAT). Final report; Studie zur Kalibrierung und Validation von Daten des Global Ozone Monitoring Experiments GOME auf ERS-2 (CAVEAT). Endbericht

    Energy Technology Data Exchange (ETDEWEB)

    Burrows, J.P.; Kuenzi, K.; Ladstaetter-Weissenmayer, A.; Langer, J. [Bremen Univ. (Germany). Inst. fuer Umweltphysik; Neuber, R.; Eisinger, M. [Alfred-Wegener-Institut fuer Polar- und Meeresforschung, Potsdam (Germany)

    2000-04-01

    The Global Ozone Monitoring Experiment (GOME) was launched on 21 April 1995 as one of six scientific instruments on board the second European remote sensing satellite (ERS-2) of the ESA. The investigations presented here aimed at assessing and improving the accuracy of the GOME measurements of sun-standardized and absolute radiation density and the derived data products. For this purpose, the GOME data were compared with measurements pf terrestrial, airborne and satellite-borne systems. For scientific reasons, the measurements will focus on the medium and high latitudes of both hemispheres, although equatorial regions were investigated as well. In the first stage, operational data products of GOME were validated, i.e. radiation measurements (spectra, level1 product) and trace gas column densities (level2 product). [German] Am 21. April 1995 wurde das Global Ozone Monitoring Experiment (GOME) als eines von insgesamt sechs wissenschaftlichen Instrumenten an Bord des zweiten europaeischen Fernerkundungssatelliten (ERS-2) der ESA ins All gebracht. Das Ziel dieses Vorhabens ist es, die Genauigkeit der von GOME durchgefuehrten Messungen von sonnennormierter und absoluter Strahlungsdichte sowie der aus ihnen abgeleiteten Datenprodukte zu bewerten und zu verbessern. Dazu sollten die GOME-Daten mit Messungen von boden-, flugzeug- und satellitengestuetzten Systemen verglichen werden. Aus wissenschaftlichen Gruenden wird der Schwerpunkt auf Messungen bei mittleren und hohen Breitengraden in beiden Hemisphaeren liegen. Jedoch wurden im Laufe des Projektzeitraumes auch Regionen in Aequatornaehe untersucht. Im ersten Schritt sollen operationelle Datenprodukte von GOME validiert werden. Dieses sind Strahlungsmessungen (Spektren, Level1-Produkt) und Spurengas-Saeulendichten (Level2-Produkt). (orig.)

  10. DOE Waste Treatability Group Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Kirkpatrick, T.D.

    1995-01-01

    This guidance presents a method and definitions for aggregating U.S. Department of Energy (DOE) waste into streams and treatability groups based on characteristic parameters that influence waste management technology needs. Adaptable to all DOE waste types (i.e., radioactive waste, hazardous waste, mixed waste, sanitary waste), the guidance establishes categories and definitions that reflect variations within the radiological, matrix (e.g., bulk physical/chemical form), and regulated contaminant characteristics of DOE waste. Beginning at the waste container level, the guidance presents a logical approach to implementing the characteristic parameter categories as part of the basis for defining waste streams and as the sole basis for assigning streams to treatability groups. Implementation of this guidance at each DOE site will facilitate the development of technically defined, site-specific waste stream data sets to support waste management planning and reporting activities. Consistent implementation at all of the sites will enable aggregation of the site-specific waste stream data sets into comparable national data sets to support these activities at a DOE complex-wide level.

  11. Autonomous gliding entry guidance with

    Directory of Open Access Journals (Sweden)

    Guo Jie

    2015-10-01

    Full Text Available This paper presents a novel three-dimensional autonomous entry guidance for relatively high lift-to-drag ratio vehicles satisfying geographic constraints and other path constraints. The guidance is composed of onboard trajectory planning and robust trajectory tracking. For trajectory planning, a longitudinal sub-planner is introduced to generate a feasible drag-versus-energy profile by using the interpolation between upper boundary and lower boundary of entry corridor to get the desired trajectory length. The associated magnitude of the bank angle can be specified by drag profile, while the sign of bank angle is determined by lateral sub-planner. Two-reverse mode is utilized to satisfy waypoint constraints and dynamic heading error corridor is utilized to satisfy no-fly zone constraints. The longitudinal and lateral sub-planners are iteratively employed until all of the path constraints are satisfied. For trajectory tracking, a novel tracking law based on the active disturbance rejection control is introduced. Finally, adaptability tests and Monte Carlo simulations of the entry guidance approach are performed. Results show that the proposed entry guidance approach can adapt to different entry missions and is able to make the vehicle reach the prescribed target point precisely in spite of geographic constraints.

  12. Axon guidance: Comm hither, Robo.

    Science.gov (United States)

    Couch, Jessica; Condron, Barry

    2002-10-29

    In the developing CNS, commissural axons are initially attracted to the midline, but after crossing they acquire sensitivity to midline repellent cues which prevent re-crossing. Recent studies have shed new light on the mechanism by which commissural axons change their sensitivity to guidance cues after crossing the midline.

  13. Modeling and controlling a robotic convoy using guidance laws strategies.

    Science.gov (United States)

    Belkhouche, Fethi; Belkhouche, Boumediene

    2005-08-01

    This paper deals with the problem of modeling and controlling a robotic convoy. Guidance laws techniques are used to provide a mathematical formulation of the problem. The guidance laws used for this purpose are the velocity pursuit, the deviated pursuit, and the proportional navigation. The velocity pursuit equations model the robot's path under various sensors based control laws. A systematic study of the tracking problem based on this technique is undertaken. These guidance laws are applied to derive decentralized control laws for the angular and linear velocities. For the angular velocity, the control law is directly derived from the guidance laws after considering the relative kinematics equations between successive robots. The second control law maintains the distance between successive robots constant by controlling the linear velocity. This control law is derived by considering the kinematics equations between successive robots under the considered guidance law. Properties of the method are discussed and proven. Simulation results confirm the validity of our approach, as well as the validity of the properties of the method. Index Terms-Guidance laws, relative kinematics equations, robotic convoy, tracking.

  14. Equal employment opportunity plan development guidance

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-09-01

    The purpose of this publication is to provide instructions for the development of EEO Plans for Fiscal Year 1979. It supplements the National EEO Plan for the Department of Energy issued in August 1978 (DOE/S-0002). The material included should be used immediately as guidance to develop, document, and implement subordinate echelon commitments to EEO. A schedule for the development and submission of EEO Plans is included. Most of the continuing requirements will be published at a later date as part of the directives system. Any comments or helpful suggestions concerned with the program outlined would be appreciated by the Office of Equal Opportunity.

  15. Avoiding plagiarism: guidance for nursing students.

    Science.gov (United States)

    Price, Bob

    The pressures of study, diversity of source materials, past assumptions relating to good writing practice, ambiguous writing guidance on best practice and students' insecurity about their reasoning ability, can lead to plagiarism. With the use of source checking software, there is an increased chance that plagiarised work will be identified and investigated, and penalties given. In extreme cases, plagiarised work may be reported to the Nursing and Midwifery Council and professional as well as academic penalties may apply. This article provides information on how students can avoid plagiarism when preparing their coursework for submission.

  16. Medicare Provider Data - Hospice Providers

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Hospice Utilization and Payment Public Use File provides information on services provided to Medicare beneficiaries by hospice providers. The Hospice PUF...

  17. Secure Data Transfer Guidance for Industrial Control and SCADA Systems

    Energy Technology Data Exchange (ETDEWEB)

    Mahan, Robert E.; Fluckiger, Jerry D.; Clements, Samuel L.; Tews, Cody W.; Burnette, John R.; Goranson, Craig A.; Kirkham, Harold

    2011-09-01

    This document was developed to provide guidance for the implementation of secure data transfer in a complex computational infrastructure representative of the electric power and oil and natural gas enterprises and the control systems they implement. For the past 20 years the cyber security community has focused on preventative measures intended to keep systems secure by providing a hard outer shell that is difficult to penetrate. Over time, the hard exterior, soft interior focus changed to focus on defense-in-depth adding multiple layers of protection, introducing intrusion detection systems, more effective incident response and cleanup, and many other security measures. Despite much larger expenditures and more layers of defense, successful attacks have only increased in number and severity. Consequently, it is time to re-focus the conventional approach to cyber security. While it is still important to implement measures to keep intruders out, a new protection paradigm is warranted that is aimed at discovering attempted or real compromises as early as possible. Put simply, organizations should take as fact that they have been, are now, or will be compromised. These compromises may be intended to steal information for financial gain as in the theft of intellectual property or credentials that lead to the theft of financial resources, or to lie silent until instructed to cause physical or electronic damage and/or denial of services. This change in outlook has been recently confirmed by the National Security Agency [19]. The discovery of attempted and actual compromises requires an increased focus on monitoring events by manual and/or automated log monitoring, detecting unauthorized changes to a system's hardware and/or software, detecting intrusions, and/or discovering the exfiltration of sensitive information and/or attempts to send inappropriate commands to ICS/SCADA (Industrial Control System/Supervisory Control And Data Acquisition) systems.

  18. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2003-04-30

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: ''each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application.'' They further state: ''each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application.'' Chapter 9.0 of the SARP charges the WIPP management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with 10 CFR 71.11. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. CBFO will evaluate the issue and notify the NRC if required. This document provides the instructions to be followed to operate, maintain, and test the TRUPACT-II and HalfPACT packaging. The intent of these instructions is to standardize operations. All users will follow these instructions or equivalent instructions that assure operations are safe and meet the requirements of the SARPs.

  19. 78 FR 25758 - Migratory Birds; Eagle Conservation Plan Guidance: Module 1-Land-Based Wind Energy, Version 2

    Science.gov (United States)

    2013-05-02

    ...-- Land-Based Wind Energy, Version 2 AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of... Guidance: Module 1--Land-based Wind Energy, Version 2 is available. The guidance provides recommendations... issued a draft of The Eagle Conservation Plan Guidance: Module 1-- Land-based Wind Energy for public...

  20. 76 FR 13629 - Revised Draft Guidance for Industry on User Fee Waivers, Reductions, and Refunds for Drug and...

    Science.gov (United States)

    2011-03-14

    ... Food, Drug, and Cosmetic Act (the FD&C Act). This revised draft guidance describes the types of waivers... guidance also provides clarification on related issues such as user fee exemptions for orphan drugs. After... HUMAN SERVICES Food and Drug Administration Revised Draft Guidance for Industry on User Fee Waivers...

  1. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-06-01

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the U.S. Department of Energy (DOE) or the Waste Isolation Pilot Plant (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required. In accordance with 10 CFR Part 71, certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21 regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to these regulations are

  2. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2008-09-11

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the pplication." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the U.S. Department of Energy (DOE) or the Waste Isolation Pilot Plant (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required. In accordance with 10 CFR Part 71, certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21 regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to these regulations are

  3. Evaluation of a mobile augmented reality application for image guidance of neurosurgical interventions.

    Science.gov (United States)

    Kramers, Matthew; Armstrong, Ryan; Bakhshmand, Saeed M; Fenster, Aaron; de Ribaupierre, Sandrine; Eagleson, Roy

    2014-01-01

    Image guidance can provide surgeons with valuable contextual information during a medical intervention. Often, image guidance systems require considerable infrastructure, setup-time, and operator experience to be utilized. Certain procedures performed at bedside are susceptible to navigational errors that can lead to complications. We present an application for mobile devices that can provide image guidance using augmented reality to assist in performing neurosurgical tasks. A methodology is outlined that evaluates this mode of visualization from the standpoint of perceptual localization, depth estimation, and pointing performance, in scenarios derived from a neurosurgical targeting task. By measuring user variability and speed we can report objective metrics of performance for our augmented reality guidance system.

  4. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2002-03-04

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT Shipping Package, and directly related components. This document complies with the minimum requirements as specified in TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event there is a conflict between this document and the SARP or C of C, the SARP and/or C of C shall govern. C of Cs state: ''each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application.'' They further state: ''each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application.'' Chapter 9.0 of the SAR P charges the WIPP Management and Operation (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with 10 CFR 71.11. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. CBFO will evaluate the issue and notify the NRC if required. This document details the instructions to be followed to operate, maintain, and test the TRUPACT-II and HalfPACT packaging. The intent of these instructions is to standardize these operations. All users will follow these instructions or equivalent instructions that assure operations are safe and meet the requirements of the SARPs.

  5. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2005-02-28

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the Waste Isolation Pilot Plant (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required.

  6. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2007-12-13

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the U.S. Department of Energy (DOE) or the Waste Isolation Pilot Plant (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required.In accordance with 10 CFR Part 71, certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21 regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to these regulations are

  7. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2006-04-25

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package TransporterModel II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the U.S. Department of Energy (DOE) or the Waste Isolation Pilot Plant| (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations(CFR) §71.8. Any time a user suspects or has indications that the conditions ofapproval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required.In accordance with 10 CFR Part 71, certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21 regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to these regulations are

  8. Real-time treatment feedback guidance of Pleural PDT

    Science.gov (United States)

    Zhu, Timothy C.; Kim, Michele M.; Liang, Xing; Liu, Baochang; Meo, Julia L.; Finlay, Jarod C.; Dimofte, Andreea; Rodriguez, Carmen; Simone, Charles B.; Cengel, Keith; Friedberg, Joseph S.

    2015-01-01

    Pleural photodynamic therapy (PDT) has been used as an adjuvant treatment with lung-sparing surgical treatment for mesothelioma with remarkable results. In the current intrapleural PDT protocol, a moving fiber-based point source is used to deliver the light and the light dose are monitored by 7 detectors placed in the pleural cavity. To improve the delivery of light dose uniformity, an infrared (IR) camera system is used to track the motion of the light sources. A treatment planning system uses feedback from the detectors as well as the IR camera to update light fluence distribution in real-time, which is used to guide the light source motion for uniform light dose distribution. We have improved the GUI of the light dose calculation engine to provide real-time light fluence distribution suitable for guiding the surgery to delivery light more uniformly. A dual-correction method is used in the feedback system, so that fluence calculation can match detector readings using both direct and scatter light models. An improved measurement device is developed to automatically acquire laser position for the point source. Comparison of the effects of the guidance is presented in phantom study. PMID:25999647

  9. Real-time treatment feedback guidance of Pleural PDT

    Science.gov (United States)

    Zhu, Timothy C.; Kim, Michele M.; Liang, Xing; Liu, Baochang; Meo, Julia L.; Finlay, Jarod C.; Dimofte, Andreea; Rodriguez, Carmen; Simone, Charles; Cengel, Keith; Friedberg, Joseph

    2013-03-01

    Pleural photodynamic therapy (PDT) has been used as an adjuvant treatment with lung-sparing surgical treatment for mesothelioma with remarkable results. In the current intrapleural PDT protocol, a moving fiber-based point source is used to deliver the light and the light dose are monitored by 7 detectors placed in the pleural cavity. To improve the delivery of light dose uniformity, an infrared (IR) camera system is used to track the motion of the light sources. A treatment planning system uses feedback from the detectors as well as the IR camera to update light fluence distribution in real-time, which is used to guide the light source motion for uniform light dose distribution. We have improved the GUI of the light dose calculation engine to provide real-time light fluence distribution suitable for guiding the surgery to delivery light more uniformly. A dual-correction method is used in the feedback system, so that fluence calculation can match detector readings using both direct and scatter light models. An improved measurement device is developed to automatically acquire laser position for the point source. Comparison of the effects of the guidance is presented in phantom study.

  10. 76 FR 53683 - Draft Guidance for Industry on Oversight of Clinical Investigations: A Risk-Based Approach to...

    Science.gov (United States)

    2011-08-29

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Oversight of Clinical... guidance for industry entitled ``Oversight of Clinical Investigations: A Risk-Based Approach to Monitoring... for clinical investigations of human drugs, biologics, medical devices, and combinations thereof. The...

  11. Solar electric propulsion for terminal flight to rendezvous with comets and asteroids. [using guidance algorithm

    Science.gov (United States)

    Bennett, A.

    1973-01-01

    A guidance algorithm that provides precise rendezvous in the deterministic case while requiring only relative state information is developed. A navigation scheme employing only onboard relative measurements is built around a Kalman filter set in measurement coordinates. The overall guidance and navigation procedure is evaluated in the face of measurement errors by a detailed numerical simulation. Results indicate that onboard guidance and navigation for the terminal phase of rendezvous is possible with reasonable limits on measurement errors.

  12. 21 CFR 312.145 - Guidance documents.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Guidance documents. 312.145 Section 312.145 Food... HUMAN USE INVESTIGATIONAL NEW DRUG APPLICATION Miscellaneous § 312.145 Guidance documents. (a) FDA has made available guidance documents under § 10.115 of this chapter to help you to comply with certain...

  13. 21 CFR 314.445 - Guidance documents.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Guidance documents. 314.445 Section 314.445 Food... documents. (a) FDA has made available guidance documents under § 10.115 of this chapter to help you to...) maintains a list of guidance documents that apply to CDER's regulations. The list is maintained on the...

  14. 21 CFR 316.50 - Guidance documents.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Guidance documents. 316.50 Section 316.50 Food and... USE ORPHAN DRUGS Availability of Information § 316.50 Guidance documents. FDA's Office of Orphan Products Development will maintain and make publicly available a list of guidance documents that apply to...

  15. Quality Assurance in University Guidance Services

    Science.gov (United States)

    Simon, Alexandra

    2014-01-01

    In Europe there is no common quality assurance framework for the delivery of guidance in higher education. Using a case study approach in four university career guidance services in England, France and Spain, this article aims to study how quality is implemented in university career guidance services in terms of strategy, standards and models,…

  16. Career Guidance in Five English Independent Schools

    Science.gov (United States)

    Hutchinson, Jo

    2018-01-01

    English independent schools are not required to follow government statutory guidance in a number of aspects including career education and guidance, and yet many are actively engaged in careers work and this has caught the attention of policymakers. State schools are subject to statutory guidance but, according to Ofsted and other authorities, the…

  17. Agent Based Individual Traffic Guidance

    DEFF Research Database (Denmark)

    Wanscher, Jørgen

    This thesis investigates the possibilities in applying Operations Research (OR) to autonomous vehicular traffic. The explicit difference to most other research today is that we presume that an agent is present in every vehicle - hence Agent Based Individual Traffic guidance (ABIT). The next...... evolutionary step for the in-vehicle route planners is the introduction of two-way communication. We presume that the agent is capable of exactly this. Based on this presumption we discuss the possibilities and define a taxonomy and use this to discuss the ABIT system. Based on a set of scenarios we conclude...... of the project were not previously considered. We define a special inseparable cost function and develop a solution complex capable of using this cost function. In relation to calibration and estimation of statistical models used for dynamic route guidance we worked with generating random number sequences...

  18. 2011 Army Strategic Planning Guidance

    Science.gov (United States)

    2011-03-25

    TESI ) of 22,000 Soldiers, the Army’s total force by the end of the mid-term period is programmed to be 520K (AC). We will achieve a more...dwell ratios, extending TESI authority to adequately man deploying units and sustain the All-Volunteer Force, right-sizing the generating force, and... TESI Temporary End-Strength Increase WMD Weapons of Mass Destruction 2011 ARMY STRATEGIC PLANNING GUIDANCE Page 19 2011

  19. Current materiality guidance for auditors

    OpenAIRE

    McKee, Thomas E.; Eilifsen, Aasmund

    2000-01-01

    Auditors have to make materiality judgments on every audit. This is a difficult process, as both quantitative and qualitative factors have to be evaluated. Additionally, there is no formal guidance for how to implement the materiality concepts discussed in the auditing standards. Although they are sometimes difficult to make, good materiality judgments are crucial for the conduct of a successful audit as poor judgments can result in an audit that is ineffective and/or inefficient. This report...

  20. Implementing Speed and Separation Monitoring in Collaborative Robot Workcells.

    Science.gov (United States)

    Marvel, Jeremy A; Norcross, Rick

    2017-04-01

    We provide an overview and guidance for the Speed and Separation Monitoring methodology as presented in the International Organization of Standardization's technical specification 15066 on collaborative robot safety. Such functionality is provided by external, intelligent observer systems integrated into a robotic workcell. The SSM minimum protective distance function equation is discussed in detail, with consideration for the input values, implementation specifications, and performance expectations. We provide analytical analyses and test results of the current equation, discuss considerations for implementing SSM in human-occupied environments, and provide directions for technological advancements toward standardization.

  1. HFE Process Guidance and Standards for potential application to updating NRC guidance

    Energy Technology Data Exchange (ETDEWEB)

    Jacques Hugo; J. J. Persensky

    2012-07-01

    The U.S. Nuclear Regulatory Commission (NRC) reviews and evaluates the human factors engineering (HFE) programs of applicants for nuclear power plant construction permits, operating licenses, standard design certifications, and combined operating licenses. The purpose of these safety reviews is to help ensure that personnel performance and reliability are appropriately supported. Detailed design review procedures and guidance for the evaluations is provided in three key documents: the Standard Review Plan (NUREG-0800), the HFE Program Review Model (NUREG-0711), and the Human-System Interface Design Review Guidelines (NUREG-0700). These documents were last revised in 2007, 2004 and 2002, respectively. The NRC is committed to the periodic update and improvement of these guidance documents to ensure that they remain state-of-the-art design evaluation tools. Thus, the NRC has initiated a project with BNL to update the NRC guidance to remain current with recent research on human performance, advances in HFE methods and tools, and new technology. INL supported Brookhaven National Lab (BNL) to update the detailed HFE review criteria contained in NUREG-0711 and NUREG-0700 based on (1) feedback obtained from end users, (2) the results of NRC research and development efforts supporting the NRC staff’s HFE safety reviews, and (3) other material the project staff identify as applicable to the update effort. INL submitted comments on development plans and sections of NUREGs 0800, 0711, and 0700. The contractor prepared the report attached here as the deliverable for this work.

  2. Circumpolar Biodiversity Monitoring Programme coastal biodiversity monitoring background paper

    Science.gov (United States)

    McLennan, Donald; Anderson, Rebecca D.; Wegeberg, S.; Pettersvik Arvnes, Maria; Sergienko, Liudmila; Behe, Carolina; Moss-Davies, Pitseolak; Fritz, S.; Markon, Carl J.; Christensen, T.; Barry, T.; Price, C.

    2016-01-01

    In 2014, the United States (U.S.) and Canada agreed to act as co-lead countries for the initial development of the Coastal Expert Monitoring Group (CEMG) as part of the Circumpolar Biodiversity Monitoring Program (CBMP, www. cbmp.is) under the Arctic Council’s Conservation of Arctic Flora and Fauna (CAFF, www.caff.is) working group. The CAFF Management Board approved Terms of Reference for the CEMG in the spring of 2014. The primary goal of the CEMG is to develop a long term, integrated, multi-disciplinary, circumpolar Arctic Coastal Biodiversity Monitoring Plan (the Coastal Plan) that relies on science and Traditional Knowledge, and has direct and relevant application for communities, industry, government decision makers, and other users. In addition to the monitoring plan, the CAFF working group has asked the CBMP, and thus the CEMG, to develop an implementation plan that identifies timeline, costs, organizational structure and partners. This background paper provides a platform for the guidance for the development of the Coastal Plan and is produced by the CEMG with assistance from a number of experts in multiple countries.

  3. Navigation and guidance of Japanese deepspace probes encountering Halley's comet

    Science.gov (United States)

    Nishimura, T.; Matsuo, H.; Takano, T.; Kawaguchi, J.

    The techniques used by ISAS in the guidance of the Sakigake and Suisei probes, which encountered Comet Halley in March 1986, are reviewed. Consideration is given to the guidance of the last rocket stage in the direct ascent phase, midcourse maneuvers, tracking systems and communication links, the tracking strategy, trajectory-generation and orbit-determination software, and orbit-determination accuracy. Diagrams, drawings, graphs, photographs, and tables of numerical data are provided, and the ISAS positions of both probes during the first 10 days after launch are shown to be within 100 km in distance and 1 m/sec in velocity of NASA coordinate estimates.

  4. EXPERIENCE OF USING WEBINARS ON CAREER GUIDANCE AMONG THE APPLICANTS

    Directory of Open Access Journals (Sweden)

    Vitalii S. Mosiichuk

    2014-04-01

    Full Text Available This article describes the experience of career guidance to students using ICT. Technical features of conducting webinars in order to allow the participation of the maximum number of participants are disclosed. To inform students about webinars and for invitations to participate social networks popular among the youth were used, which allowed us to provide long-term feedback between teachers and students, to create a community for mutual support between members. Evaluating the effectiveness of career guidance is made on the basis of statistical data of webometric analytics systems.

  5. Implementation of NUREG-1318 guidance within the Yucca Mountain Project

    Energy Technology Data Exchange (ETDEWEB)

    La Monica, L.B.; Waddell, J.D.; Hardin, E.L.

    1990-04-01

    The US Department of Energy`s Yucca Mountain Project is implementing a quality assurance program that fulfills the requirements of the US Nuclear Regulatory Commission (NRC). Additional guidance for this program was provided in NUREG 1318, ``Technical Position on Items and Activities in the High-Level Waste Geologic Repository Program Subject to Quality Assurance Requirements`` for identification of items and activities important to public radiological safety and waste isolation. The process and organization for implementing this guidance is discussed. 3 refs., 2 figs.

  6. Implementation of NUREG 1318 guidance within the Yucca Mountain Project

    Energy Technology Data Exchange (ETDEWEB)

    La Monica, L.B.; Waddell, J.D.; Hardin, E.L. [Science Applications International Corp., Las Vegas, NV (USA)

    1990-10-01

    This paper discusses the implementation of a quality assurance program that fulfills the requirements of the U.S. Nuclear Regulatory Commission (NRC). Additional guidance for this program was provided in NUREG 1318, Technical Position on Items and Activities in the High-Level Waste Geologic Repository Program Subject to Quality Assurance Requirements for the identification of items and activities important to public radiological safety and waste isolation for placement on a Q-List and Quality Activities List and also for graded application of QA measures. The process and organization for implementing this guidance is discussed.

  7. Safety of magnetic fusion facilities: Volume 2, Guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This document provides guidance for the implementation of the requirements identified in Vol. 1 of this Standard. This guidance is intended for the managers, designers, operators, and other personnel with safety responsibilities for facilities designated as magnetic fusion facilities. While Vol. 1 is generally applicable in that requirements there apply to a wide range of fusion facilities, this volume is concerned mainly with large facilities such as the International Thermonuclear Experimental Reactor (ITER). Using a risk-based prioritization, the concepts presented here may also be applied to other magnetic fusion facilities. This volume is oriented toward regulation in the Department of Energy (DOE) environment.

  8. National Environmental Policy Act guidance: A model process

    Energy Technology Data Exchange (ETDEWEB)

    Angle, B.M.; Lockhart, V.A.T.; Sema, B.; Tuott, L.C.; Irving, J.S.

    1995-04-01

    The ``Model National Environmental Policy Act (NEPA) Process`` includes: References to regulations, guidance documents, and plans; training programs; procedures; and computer databases. Legislative Acts and reference documents from Congress, US Department of Energy, and Lockheed Idaho Technologies Company provide the bases for conducting NEPA at the Idaho National Engineering Laboratory (INEL). Lockheed Idaho Technologies Company (LITCO) NEPA / Permitting Department, the Contractor Environmental Organization (CEO) is responsible for developing and maintaining LITCO NEPA and permitting policies, guidance, and procedures. The CEO develops procedures to conduct environmental evaluations based on NEPA, Council on Environmental Quality (CEQ) regulations, and DOE guidance. This procedure includes preparation or support of environmental checklists, categorical exclusion determinations, environmental assessment determinations, environmental assessments, and environmental impact statements. In addition, the CEO uses this information to train personnel conducting environmental evaluations at the INEL. Streamlining these procedures fosters efficient use of resources, quality documents, and better decisions on proposed actions.

  9. The WODA guidance paper on underwater sound from dredging (abstract)

    NARCIS (Netherlands)

    Thomsen, F.; Borsani, F.; Clarke, D.; Jong, C.A.F. de; Witt, P. de; Holtkamp, M.; Goethals, F.; San Martin, E.; Spadaro, P.; Raalte, G. van; Jensen, A.

    2013-01-01

    The World Organisation of Dredging Associations (WODA) has identified underwater sound as an environmental issue that needs further consideration. A WODA Expert Group on Underwater Sound (WEGUS) was established to provide a guidance paper on dredging sound, impact on aquatic biota and advice on

  10. A Roadmap To The Professionalization Of Guidance And ...

    African Journals Online (AJOL)

    The paper examined guidance and counselling profession in Nigeria, which is recognized to have existed in Nigeria since 1959. Against the backdrop of poor recognition of the profession in Nigeria, this paper examined the status of the profession and provided ways of making the field a recognizable height in Nigeria.

  11. Laboratory Biosafety and Biosecurity Risk Assessment Technical Guidance Document

    Energy Technology Data Exchange (ETDEWEB)

    Astuto-Gribble, Lisa M; Caskey, Susan Adele

    2014-07-01

    The purpose of this document is threefold: 1) to describe the laboratory bio safety and biosecurity risk assessment process and its conceptual framework; 2) provide detailed guidance and suggested methodologies on how to conduct a risk assessment; and 3) present some practical risk assessment process strategies using realistic laboratory scenarios.

  12. ISO19770-1:2012 SAM process guidance

    CERN Document Server

    Canavan, Rory

    2012-01-01

    The pocket guide offers a concise summary of the principles of software asset management as conveyed by ISO 19770-1: 2012, and provides advice and guidance on how to kick-start your own SAM programme - something the Standard alone doesn't offer.

  13. Guidance Manual: Asbestos Operations & Maintenance Work Practices. Second Edition.

    Science.gov (United States)

    National Inst. of Building Sciences, Washington, DC.

    This technical manual provides detailed guidance to building owners, asbestos program managers, and operations and maintenance (O&M) workers for managing asbestos-containing materials (ACM) in buildings. The manual addresses four different types of ACM found in buildings and three different levels of precaution which may be warranted by…

  14. Career Guidance in Multicultural Societies: Identity, Alterity, Epiphanies and Pitfalls

    Science.gov (United States)

    Sultana, Ronald G.

    2017-01-01

    This paper provides a scoping approach to the issue of career guidance in multicultural societies. It starts off by exploring the meaning of "culture," moving away from "back-pack" approaches that consider culture as a set of worldviews and dispositions that are readily shed or put on, to anthropological understandings of…

  15. 76 FR 411 - Regulatory Guidance Concerning Electronic Signatures and Documents

    Science.gov (United States)

    2011-01-04

    ... Documents AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of regulatory... documents to comply with FMCSA regulations. This guidance provides the motor carrier industry, Federal... information regarding FMCSA's acceptance of electronic signature on documents required by the Federal Motor...

  16. Management and Control | Ajaiya | Nigerian Journal of Guidance ...

    African Journals Online (AJOL)

    This article provides a practical guide on how tp use positive reinforcement through behaviour modification technique for classroom management and control. Its concept and process as well as its relevance to learning are presented as a more acceptable alternative to the use of punishment. Nigerian Journal of Guidance ...

  17. Series: Practical guidance to qualitative research : part 1: introduction

    NARCIS (Netherlands)

    Albine Moser; Irene Korstjens

    2017-01-01

    In the course of our supervisory work over the years, we have noticed that qualitative research tends to evoke a lot of questions and worries, so-called Frequently Asked Questions. This journal series of four articles intends to provide novice researchers with practical guidance for

  18. Automated Guidance for Thermodynamics Essays: Critiquing versus Revisiting

    Science.gov (United States)

    Donnelly, Dermot F.; Vitale, Jonathan M.; Linn, Marcia C.

    2015-01-01

    Middle school students struggle to explain thermodynamics concepts. In this study, to help students succeed, we use a natural language processing program to analyze their essays explaining the aspects of thermodynamics and provide guidance based on the automated score. The 346 sixth-grade students were assigned to either the critique condition…

  19. Asset Management Plans, Appraisal Guidance for 2003-04.

    Science.gov (United States)

    Department for Education and Skills, London (England).

    This document is one in a series which aims to assist Local Authorities in Britain with asset management planning (AMPs) for schools. AMPs set out the information needed, and the criteria used, to make decisions about spending on school premises. The document provides guidance on the appraisal of school AMPs in 2002 to inform 3-year formulaic…

  20. Anticipatory guidance in pediatric practice.

    Science.gov (United States)

    Reisinger, K S; Bires, J A

    1980-12-01

    Physicians, by their collective positions in society and their individual interaction with patients, can be facilitators in helping families adopt more healthful ways of living. This study addresses the issue of the amount of time pediatricians in private practice spend with patients during well-child visits and the proportion of that time they devote to discussing potential health problems. The study population consisted of a random sample of pediatricians in the metropolitan Pittsburgh area. Observation of physician-patient interactions were made during one day in each of 23 pediatricians' offices. During the days of observation there were 305 well-child visits. The time spent with each patient averaged 10.3 minutes. Anticipatory guidance constituted 8.4% of total visit time. Pediatricians in group practice or partnerships and those recently trained spent more time with patients and a greater part of their time in anticipatory guidance. The amount of time during the well-child visit spent in anticipatory guidance varied with the age of the patient. The most time discussing potential future problems was spent with parents of infants less than 5 months of age (1 minute 37 seconds), with only an average of seven seconds being spent with adolescents. Of particular note was the lack of time spent discussing issues of safety, sex, behavior and growth. Because pediatricians spend more than 60% of their in-office time seeing patients for well-child care, they have an excellent opportunity to motivate parents and patients to change to more healthful ways of living. This opportunity will be lost however unless pediatricians reorient their priorities by addressing currently unmet health problems.

  1. 75 FR 41498 - Draft Guidance for Tobacco Retailers on Tobacco Retailer Training Programs; Availability; Agency...

    Science.gov (United States)

    2010-07-16

    ... does provide for lower civil money penalties for violations of access, advertising, and promotion... electronic or written comments on the draft guidance and on the proposed collection of information by September 14, 2010. ADDRESSES: Submit electronic comments on the draft guidance, including comments...

  2. 78 FR 54657 - Guidance for Tobacco Retailers on Tobacco Retailer Training Programs; Availability

    Science.gov (United States)

    2013-09-05

    ... Control Act does provide for lower civil money penalties for violations of sale and distribution.... DATES: Submit either electronic or written comments on this guidance at any time. General comments on... SUPPLEMENTARY INFORMATION section for electronic access to the guidance document. Submit electronic comments on...

  3. 75 FR 57963 - Draft Guidance for Industry and Food and Drug Administration Staff; Establishing the Performance...

    Science.gov (United States)

    2010-09-23

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration... Helicobacter pylori; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food... pylori.'' This draft guidance document provides industry and agency staff with updated recommendations...

  4. 78 FR 68852 - Draft Guidance for Industry on Acrylamide in Foods; Availability

    Science.gov (United States)

    2013-11-15

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Acrylamide in Foods...: Acrylamide in Foods.'' The draft guidance is intended to provide information that may help growers, manufacturers, and food service operators reduce acrylamide in certain foods. Acrylamide is a chemical that can...

  5. 76 FR 9028 - Guidance for Industry: Potency Tests for Cellular and Gene Therapy Products; Availability

    Science.gov (United States)

    2011-02-16

    ... Industry: Potency Tests for Cellular and Gene Therapy Products'' dated January 2011. The guidance document provides manufacturers of cellular and gene therapy (CGT) products with recommendations for developing... document entitled ``Guidance for Industry: Potency Tests for Cellular and Gene Therapy Products'' dated...

  6. New Emerging Issues about Guidance and Counselling in an Accreditation of Prior and Experiential Learning Process

    Science.gov (United States)

    Sanséau, Pierre-Yves; Ansart, Sandrine

    2014-01-01

    The aim of this research is to examine special features of guidance and counselling roles in a process of accreditation of prior and experiential learning (APEL). More specifically, we have two main goals: to identify any possible distinctive feature of guidance and counselling provided during a skills-oriented APEL procedure; and to highlight any…

  7. 75 FR 73109 - Guidance for Industry on Antibacterial Drug Products: Use of Noninferiority Trials to Support...

    Science.gov (United States)

    2010-11-29

    ... this guidance is to provide information on FDA's current thinking regarding appropriate use of noninferiority (NI) clinical trial designs to evaluate antibacterial drug products. The Agency's thinking in this... HUMAN SERVICES Food and Drug Administration Guidance for Industry on Antibacterial Drug Products: Use of...

  8. 78 FR 37230 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Science.gov (United States)

    2013-06-20

    ... current thinking on product-specific design of BE studies to support ANDAs. They do not create or confer... HUMAN SERVICES Food and Drug Administration Draft and Revised Draft Guidances for Industry Describing... provide product-specific guidance on the design of BE studies to support abbreviated new drug applications...

  9. 77 FR 74669 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Science.gov (United States)

    2012-12-17

    ... Agency's current thinking on product-specific design of BE studies to support ANDAs. They do not create... HUMAN SERVICES Food and Drug Administration Draft and Revised Draft Guidances for Industry Describing... provide product-specific guidance on the design of BE studies to support abbreviated new drug applications...

  10. 78 FR 66745 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Science.gov (United States)

    2013-11-06

    ... thinking on product-specific design of BE studies to support ANDAs. They do not create or confer any rights... HUMAN SERVICES Food and Drug Administration Draft and Revised Draft Guidances for Industry Describing... provide product-specific guidance on the design of BE studies to support abbreviated new drug applications...

  11. 75 FR 3238 - Draft Guidance for Industry and Food and Drug Administration Staff; Heart Valves...

    Science.gov (United States)

    2010-01-20

    ... Organization For Standardization (ISO), ISO 5840:2005, ``Cardiovascular Implants -- Cardiac Valve Prostheses'' (ISO 5840). Although the draft guidance document provides complementary information to ISO 5840:2005, the draft guidance document can also be used with other methods equivalent to ISO 5840:2005. II...

  12. 76 FR 70150 - Draft Guidance for Industry and Food and Drug Administration Staff; Investigational Device...

    Science.gov (United States)

    2011-11-10

    ... Internet. A search capability for all CDRH guidance documents is available at http://www.fda.gov/Medical... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND... is finalized. This draft guidance addresses the information that should be provided to FDA in support...

  13. 77 FR 13172 - Guidance on the Use of Rounding in Air Fare Advertisements

    Science.gov (United States)

    2012-03-05

    ... Office of The Secretary Guidance on the Use of Rounding in Air Fare Advertisements AGENCY: Office of the... Fare Advertisements. SUMMARY: The Department is publishing the following notice providing guidance on the use of rounding in air fare advertisements. FOR FURTHER INFORMATION CONTACT: Nicholas Lowry...

  14. 77 FR 11618 - Additional Guidance on Airfare/Air Tour Price Advertisements

    Science.gov (United States)

    2012-02-27

    ... Office of the Secretary Additional Guidance on Airfare/Air Tour Price Advertisements AGENCY: Office of.../air tour price advertisements. SUMMARY: The Department is publishing the following notice providing additional guidance on airfare/air tour price advertisements. FOR FURTHER INFORMATION CONTACT: Nicholas Lowry...

  15. 77 FR 10535 - Final Guidances for Industry Describing Product-Specific Bioequivalence Recommendations...

    Science.gov (United States)

    2012-02-22

    ... guidances represent the Agency's current thinking on product-specific design of BE studies to support ANDAs... bioequivalence (BE) recommendations. The recommendations provide product-specific guidance on the design of BE... Recommendations for Specific Products,'' which explained the process that would be used to make product-specific...

  16. 77 FR 35688 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Science.gov (United States)

    2012-06-14

    ... guidances represent the Agency's current thinking on product-specific design of BE studies to support ANDAs... provide product-specific guidance on the design of BE studies to support abbreviated new drug applications... the process that would be used to make product-specific BE recommendations available to the public on...

  17. 77 FR 10536 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Science.gov (United States)

    2012-02-22

    ...). The guidances represent the Agency's current thinking on product-specific design of BE studies to... provide product-specific guidance on the design of BE studies to support abbreviated new drug applications... the process that would be used to make product-specific BE recommendations available to the public on...

  18. The Consequences of Fading Instructional Guidance on Delayed Performance: The Case of Financial Services Training

    Science.gov (United States)

    Kissane, Mark; Kalyuga, Slava; Chandler, Paul; Sweller, John

    2008-01-01

    Empirical studies within a cognitive load framework have determined that for novice learners, worked examples provide appropriate levels of instructional guidance. As learners advance in specific subject domains, worked examples should be gradually replaced by practice problems with limited guidance. This study compared performance, both…

  19. Agent Based Individual Traffic guidance

    DEFF Research Database (Denmark)

    Wanscher, Jørgen Bundgaard

    2004-01-01

    When working with traffic planning or guidance it is common practice to view the vehicles as a combined mass. >From this models are employed to specify the vehicle supply and demand for each region. As the models are complex and the calculations are equally demanding the regions and the detail...... of the road network is aggregated. As a result the calculations reveal only what the mass of vehicles are doing and not what a single vehicle is doing. This is the crucial difference to ABIT (Agent Based Individual Trafficguidance). ABIT is based on the fact that information on the destination of each vehicle...

  20. Orthobiologic Interventions Using Ultrasound Guidance.

    Science.gov (United States)

    Malanga, Gerard; Abdelshahed, Dena; Jayaram, Prathap

    2016-08-01

    The application of regenerative therapies for the treatment of musculoskeletal conditions has emerged over the last decade with recent acceleration. These include prolotherapy, platelet-rich plasma, and mesenchymal stem cell therapy. These strategies augment the body's innate physiology to heal pathologic processes. This article presents an overview of platelet-rich plasma and mesenchymal stem cell therapy for the treatment of musculoskeletal injuries. A brief literature review is included, as are techniques for the use of ultrasound guidance to assist with these procedures. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Quality guidance and quality formation

    DEFF Research Database (Denmark)

    Poulsen, Carsten Stig; Juhl, Hans Jørn; Kristensen, Kai

    1996-01-01

    This paper presents an extension of the quality guidance model of Steenkamp and van Trijp that includes consumer quality formation processes. Quality expectations and quality experiences are seen as antecedents of perceived overall product quality conceptual model is applied using LISREL to a data...... set on Danish butter cookies. Five plausible models of the relation between expectation, experience and perceived product quality are estimated. Finally one model is selected on the basis of three criteria: chi-square, RMSEA and AIC: The results show a model where expectations are indirectly related...... to perceived quality through experience. Udgivelsesdato: APR...

  2. Energy angular momentum closed-loop guidance

    Science.gov (United States)

    Patera, Russell P.

    2015-03-01

    A novel guidance algorithm for launch vehicle ascent to the desired mission orbit is proposed. The algorithm uses total specific energy and orbital angular momentum as new state vector parameters. These parameters are ideally suited for the ascent guidance task, since the guidance algorithm steers the launch vehicle along a pre-flight optimal trajectory in energy angular momentum space. The guidance algorithm targets apogee, perigee, inclination and right ascension of ascending node. Computational complexities are avoided by eliminating time in the guidance computation and replacing it with angular momentum magnitude. As a result, vehicle acceleration, mass, thrust, length of motor burns, and staging times are also eliminated from the pitch plane guidance calculations. The algorithm does not involve launch vehicle or target state propagation, which results in minimal computational effort. Proof of concept of the new algorithm is presented using several numerical examples that illustrate performance results.

  3. Can a physical activity monitor provide a valid measure of arm elevation angle? A study to assess agreement between the SenseWear Mini Armband and the universal goniometer.

    Science.gov (United States)

    Hirschhorn, Andrew D; Lockhart, John W; Breckenridge, John D

    2015-03-03

    We undertook the current study to assess whether an accelerometer-based physical activity monitor, the SenseWear Mini Armband (SMA), could be used to provide data on static arm elevation, and to assess the agreement between static arm elevation measures obtained using SMA-derived data and those obtained with a universal goniometer. Using a universal goniometer, healthy adult subjects (n = 25, age 30 ± 9 years) had each of right and left arms positioned in a series of set positions between arm-by-side and maximal active arm flexion (anteversion), and arm-by-side and maximal active arm abduction. Subjects wore the SMA throughout positioning, and SMA accelerometer data was used to retrospectively calculate/derive arm elevation angle using a manufacturer-provided algorithm. The Bland-Altman method was used to assess agreement between goniometer-set and SMA-derived arm elevation angles. There were significant differences between goniometer-set and SMA-derived arm elevation angles for elevation angles ≤ 30 degrees and ≥ 90 degrees (p goniometer-set and SMA-derived elevation angles. Adjustment of the manufacturer-provided algorithm for deriving arm elevation angle corrected for this systematic difference, and resulted in 95% limits of agreement ± 12 degrees (flexion) and ± 13 degrees (abduction) across the full range of arm elevation. The SMA can be used to record data allowing derivation of static arm elevation angle in the upright position, 95% limits of agreement with the universal goniometer being similar to those reported for digital inclinometers and gyroscopes. Physiotherapists looking for innovative methods of recording upper limb range of motion should consider the potential of accelerometer-based physical activity monitors such as the SMA.

  4. Regulatory guidance on soil cover systems

    Energy Technology Data Exchange (ETDEWEB)

    Kane, J.D. [Nuclear Regulatory Commission, Washington, DC (United States)

    1991-12-31

    The US Nuclear Regulatory Commission (NRC) in September 1991, completed revisions to 14 sections of the Standard Review Plan (SRP) for the Review of a License Application for a Low-Level Radioactive Waste Disposal Facility. The major purposes of the SRP are to ensure the quality and uniformity of the NRC staff`s safety reviews, and to present a well-defined base from which to evaluate the acceptability of information and data provided in the Safety Analysis Report (SAR) portion of the license application. SRP 3.2, entitled, Design Considerations for Normal and Abnormal/Accident Conditions, was one of the sections that was revised by the NRC staff. This revision was completed to provide additional regulatory guidance on the important considerations that need to be addressed for the proper design and construction of soil cover systems that are to be placed over the LLW. The cover system over the waste is acknowledged to be one of the most important engineered barriers for the long-term stable performance of the disposal facility. The guidance in revised SRP 3.2 summarizes the previous efforts and recommendations of the US Army Corps of Engineers (COE), and a peer review panel on the placement of soil cover systems. NRC published these efforts in NUREG/CR-5432. The discussions in this paper highlight selected recommendations on soil cover issues that the NRC staff considers important for ensuring the safe, long-term performance of the soil cover systems. The development phases to be discussed include: (1) cover design; (2) cover material selection; (3) laboratory and field testing; (4) field placement control and acceptance; and (5) penetrations through the constructed covers.

  5. Hybrid Guidance System for Relative Navigation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Future NASA architectures and missions will involve many distributed platforms that must work together. This in turn requires guidance, navigation and control...

  6. The next generation of the World Health Organization's global antiretroviral guidance

    Directory of Open Access Journals (Sweden)

    Gottfried Hirnschall

    2013-06-01

    Full Text Available The 2013 World Health Organization’s (WHO Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection provide more than 50 new recommendations across the continuum of HIV care, including recommendations on HIV testing, using antiretroviral drugs for prevention, linking individuals to HIV care and treatment services, initiating and maintaining antiretroviral therapy (ART and monitoring treatment. Guidance is provided across all age groups and populations of adults, pregnant and breastfeeding women, adolescents and key populations. The guidelines are based on a public health approach to expanding the use of ARV drugs for HIV treatment and prevention, with a particular focus on resource-limited settings. The most important new clinical recommendations include: treating adults, adolescents and older children earlier – starting ART in all individuals with a CD4 cell count of 500 cells/mm3 or less (but giving priority to those with advanced clinical disease or a CD4 cell count less than 350 cells/mm3; starting ART at any CD4 cell count in certain populations, including those with active TB (existing recommendation, Hepatitis B infection and severe chronic liver disease, HIV-positive partners in serodiscordant couples (existing recommendation, pregnant and breastfeeding women, and children younger than 5 years of age; a preferred first-line ART regimen of Tenofovir+3TC or FTC+ Efavirenz as a once-daily fixed-dose combination for adults, pregnant women, and children aged 3 years and older; and the use of viral load testing as the preferred approach to monitoring the response to ART and to diagnose treatment failure. Guidance is also provided on enhancing the efficiency and effectiveness of HIV services, including strategies to improve retention in care, and adherence to ART; task-shifting to address human resource gaps; decentralizing delivery of ART to primary health care, and integrating ART services within

  7. POSSIBILITY OF CAREER GUIDANCE ORGANIZATION IN TODAY UNIVERSITY

    Directory of Open Access Journals (Sweden)

    Irina Serafimovna Begantsova

    2014-11-01

    Full Text Available The article presents the authors’ experience with students as a part of career guidance in terms of modern university. In the context of the stated problems, the authors examine such concepts as "career guidance", "readiness to professional choice", "socio-psychological characteristics of applicants".In the article presented, the authors emphasize that targeted career guidance work allows not only to assist students in choosing a career, but also provides a man with psychological readiness to the choice of a profession, the very awareness of this choice.The diagnostic tools used are especially noteworthy, it provided with initial understanding about potential consumers of educational services.The developed socio-psychological characteristics of potential applicants has a significant role for theory and practice, it allowed to formulate the strategy and tactics of interaction with students, parents, teachers, and other potential consumers of educational services, and it also allowed to outline a strategy for career guidance in higher educational institutions.The article is of interest to specialists in the field of applied psychology and social work.

  8. Physical Guidance of Cell Migration

    Science.gov (United States)

    Losert, Wolfgang

    Cells migrate as individuals or groups, to perform critical functions in life from organ development to wound healing and the immune response. While directed migration of cells is often mediated by chemical or physical gradients, our recent work has demonstrated that the physical properties of the microenvironment can also control and guide migration. I will describe how an underlying wave-like process of the actin scaffolding drives persistent migration, and how such actin waves are nucleated and guided by the texture of the microenvironment. Based on this observation we design textures capable of guiding cells in a single preferred direction using local asymmetries in nano/microtopography on subcellular scales, or altering migration in other ways. This phenomenon is observed both for the pseudopod-dominated migration of Dictyostelium cells and for the lamellipod-driven migration of human neutrophils. The conservation of this mechanism across cell types suggests that actin-wave-based guidance is important in biology and physiology.

  9. D & D screening risk evaluation guidance

    Energy Technology Data Exchange (ETDEWEB)

    Robers, S.K.; Golden, K.M.; Wollert, D.A.

    1995-09-01

    The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D&D) facilities. Although this method has been developed for D&D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D&D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the hypothetical risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risks to human health due to factors other than that of contaminants. Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form, and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, as determined on a project-by-project basis.

  10. Aims and Issues in Guidance Counselling.

    Science.gov (United States)

    Guichard, Jean

    2002-01-01

    Career guidance has changed in response to workplace changes, theories, and ethical, political, and social objectives. In the current world context, the central aim of guidance should be revised to assisting individuals to reach their potential by helping others to do the same. (Contains 74 references.) (SK)

  11. Vocational Guidance Requests within the International Scene

    Science.gov (United States)

    Goodman, Jane; Gillis, Sarah

    2009-01-01

    This article summarizes the work of a diverse group of researchers and practitioners from 5 continents on "Vocational Guidance Requests Within the International Scene" presented in the discussion group at a symposium of the International Association for Educational and Vocational Guidance, the Society for Vocational Psychology, and the…

  12. Driving change : sustainable development action plans Guidance

    OpenAIRE

    Sustainable Development Commission

    2008-01-01

    This guidance builds upon the Sustainable Development Commission’s previous guidance, Getting Started (August 2005), which set out the basic elements that the Sustainable Development Commission would expect to see in a good Sustainable Development Action Plan. Publisher PDF Original published August 2005.

  13. 78 FR 57450 - State Rail Plan Guidance

    Science.gov (United States)

    2013-09-18

    ... authorized in the Act and available under the High-Speed Intercity Passenger Rail program. This guidance... qualifies States to receive grants for high-speed rail only. Response: Operational information about all... Federal Railroad Administration State Rail Plan Guidance AGENCY: Federal Railroad Administration (FRA...

  14. Guidance Counsellor Strategies for Handling Bullying

    Science.gov (United States)

    Power-Elliott, Michleen; Harris, Gregory E.

    2012-01-01

    The purpose of this exploratory-descriptive study was to examine how guidance counsellors in the province of Newfoundland and Labrador would handle a specific verbal-relational bullying incident. Also of interest was guidance counsellor involvement and training in bullying programmes and Positive Behaviour Supports. Data for this study was…

  15. Guidance trajectories for aeroassisted orbital transfer

    Science.gov (United States)

    Miele, A.

    1990-01-01

    Research on aerobraking guidance schemes is presented. The intent is to produce aerobraking guidance trajectories exhibiting many of the desirable characteristics of optimal aerobraking trajectories. Both one-control schemes and two-control schemes are studied. The research is in the interest of aeroassisted flight experiment vehicles (AFE) and aeroassisted orbital transfer (AOT) vehicles.

  16. Ultrasound Guidance for Botulinum Neurotoxin Chemodenervation Procedures.

    Science.gov (United States)

    Alter, Katharine E; Karp, Barbara I

    2017-12-28

    Injections of botulinum neurotoxins (BoNTs) are prescribed by clinicians for a variety of disorders that cause over-activity of muscles; glands; pain and other structures. Accurately targeting the structure for injection is one of the principle goals when performing BoNTs procedures. Traditionally; injections have been guided by anatomic landmarks; palpation; range of motion; electromyography or electrical stimulation. Ultrasound (US) based imaging based guidance overcomes some of the limitations of traditional techniques. US and/or US combined with traditional guidance techniques is utilized and or recommended by many expert clinicians; authors and in practice guidelines by professional academies. This article reviews the advantages and disadvantages of available guidance techniques including US as well as technical aspects of US guidance and a focused literature review related to US guidance for chemodenervation procedures including BoNTs injection.

  17. Ultrasound Guidance for Botulinum Neurotoxin Chemodenervation Procedures

    Directory of Open Access Journals (Sweden)

    Katharine E. Alter

    2017-12-01

    Full Text Available Injections of botulinum neurotoxins (BoNTs are prescribed by clinicians for a variety of disorders that cause over-activity of muscles; glands; pain and other structures. Accurately targeting the structure for injection is one of the principle goals when performing BoNTs procedures. Traditionally; injections have been guided by anatomic landmarks; palpation; range of motion; electromyography or electrical stimulation. Ultrasound (US based imaging based guidance overcomes some of the limitations of traditional techniques. US and/or US combined with traditional guidance techniques is utilized and or recommended by many expert clinicians; authors and in practice guidelines by professional academies. This article reviews the advantages and disadvantages of available guidance techniques including US as well as technical aspects of US guidance and a focused literature review related to US guidance for chemodenervation procedures including BoNTs injection.

  18. An Approximate Optimal Maximum Range Guidance Scheme for Subsonic Unpowered Gliding Vehicles

    Directory of Open Access Journals (Sweden)

    Dao-Chi Zhang

    2015-01-01

    Full Text Available This study investigates the maximum gliding range problems of subsonic unpowered gliding vehicles and proposes an approximate optimal maximum range guidance scheme. First, the gliding flight path angle corresponding to constant dynamic pressure is derived. A lift-to-drag ratio (L/D inversely proportional to the dynamic pressure is then proven. On this basis, the calculation method of an optimal dynamic pressure (ODP profile with a maximum L/D throughout the flight is presented. A guidance scheme for tracking the ODP profile, which uses the flight path angle as control variable, is then designed. The maximum ranges of the unpowered gliding vehicle obtained by the proposed guidance scheme and pseudospectral method are compared. Results show that the guidance scheme provides an accurate approximation of the optimal results, and the errors are less than 2%. The proposed guidance scheme is easy to implement and is not influenced by wind compared with numerical schemes.

  19. Guidance, Navigation and Control of Unmanned Airships under Time-Varying Wind for Extended Surveillance

    Directory of Open Access Journals (Sweden)

    Ghassan Atmeh

    2016-02-01

    Full Text Available This paper deals with the control of lighter-than-air vehicles, more specifically the design of an integrated guidance, navigation and control (GNC scheme that is capable of navigating an airship through a series of constant-altitude, planar waypoints. Two guidance schemes are introduced, a track-specific guidance law and a proportional navigation guidance law, that provide the required signals to the corresponding controllers based on the airship position relative to a target waypoint. A novel implementation of the extended Kalman filter, namely the scheduled extended Kalman filter, estimates the required states and wind speed to enhance the performance of the track-specific guidance law in the presence of time-varying wind. The performance of the GNC system is tested using a high fidelity nonlinear dynamic simulation for a variety of flying conditions. Representative results illustrate the performance of the integrated system for chosen flight conditions.

  20. Glypican Is a Modulator of Netrin-Mediated Axon Guidance.

    Directory of Open Access Journals (Sweden)

    Cassandra R Blanchette

    2015-07-01

    Full Text Available Netrin is a key axon guidance cue that orients axon growth during neural circuit formation. However, the mechanisms regulating netrin and its receptors in the extracellular milieu are largely unknown. Here we demonstrate that in Caenorhabditis elegans, LON-2/glypican, a heparan sulfate proteoglycan, modulates UNC-6/netrin signaling and may do this through interactions with the UNC-40/DCC receptor. We show that developing axons misorient in the absence of LON-2/glypican when the SLT-1/slit guidance pathway is compromised and that LON-2/glypican functions in both the attractive and repulsive UNC-6/netrin pathways. We find that the core LON-2/glypican protein, lacking its heparan sulfate chains, and secreted forms of LON-2/glypican are functional in axon guidance. We also find that LON-2/glypican functions from the epidermal substrate cells to guide axons, and we provide evidence that LON-2/glypican associates with UNC-40/DCC receptor-expressing cells. We propose that LON-2/glypican acts as a modulator of UNC-40/DCC-mediated guidance to fine-tune axonal responses to UNC-6/netrin signals during migration.

  1. Glypican Is a Modulator of Netrin-Mediated Axon Guidance.

    Science.gov (United States)

    Blanchette, Cassandra R; Perrat, Paola N; Thackeray, Andrea; Bénard, Claire Y

    2015-07-01

    Netrin is a key axon guidance cue that orients axon growth during neural circuit formation. However, the mechanisms regulating netrin and its receptors in the extracellular milieu are largely unknown. Here we demonstrate that in Caenorhabditis elegans, LON-2/glypican, a heparan sulfate proteoglycan, modulates UNC-6/netrin signaling and may do this through interactions with the UNC-40/DCC receptor. We show that developing axons misorient in the absence of LON-2/glypican when the SLT-1/slit guidance pathway is compromised and that LON-2/glypican functions in both the attractive and repulsive UNC-6/netrin pathways. We find that the core LON-2/glypican protein, lacking its heparan sulfate chains, and secreted forms of LON-2/glypican are functional in axon guidance. We also find that LON-2/glypican functions from the epidermal substrate cells to guide axons, and we provide evidence that LON-2/glypican associates with UNC-40/DCC receptor-expressing cells. We propose that LON-2/glypican acts as a modulator of UNC-40/DCC-mediated guidance to fine-tune axonal responses to UNC-6/netrin signals during migration.

  2. Guidance and Control Software Project Data - Volume 2: Development Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the development documents from the GCS project. Volume 2 contains three appendices: A. Guidance and Control Software Development Specification; B. Design Description for the Pluto Implementation of the Guidance and Control Software; and C. Source Code for the Pluto Implementation of the Guidance and Control Software

  3. SPAR-H Step-by-Step Guidance

    Energy Technology Data Exchange (ETDEWEB)

    April M. Whaley; Dana L. Kelly; Ronald L. Boring; William J. Galyean

    2012-06-01

    Step-by-step guidance was developed recently at Idaho National Laboratory for the US Nuclear Regulatory Commission on the use of the Standardized Plant Analysis Risk-Human Reliability Analysis (SPAR-H) method for quantifying Human Failure Events (HFEs). This work was done to address SPAR-H user needs, specifically requests for additional guidance on the proper application of various aspects of the methodology. This paper overviews the steps of the SPAR-H analysis process and highlights some of the most important insights gained during the development of the step-by-step directions. This supplemental guidance for analysts is applicable when plant-specific information is available, and goes beyond the general guidance provided in existing SPAR-H documentation. The steps highlighted in this paper are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff.

  4. Augmented Reality Image Guidance in Minimally Invasive Prostatectomy

    Science.gov (United States)

    Cohen, Daniel; Mayer, Erik; Chen, Dongbin; Anstee, Ann; Vale, Justin; Yang, Guang-Zhong; Darzi, Ara; Edwards, Philip'eddie'

    This paper presents our work aimed at providing augmented reality (AR) guidance of robot-assisted laparoscopic surgery (RALP) using the da Vinci system. There is a good clinical case for guidance due to the significant rate of complications and steep learning curve for this procedure. Patients who were due to undergo robotic prostatectomy for organ-confined prostate cancer underwent preoperative 3T MRI scans of the pelvis. These were segmented and reconstructed to form 3D images of pelvic anatomy. The reconstructed image was successfully overlaid onto screenshots of the recorded surgery post-procedure. Surgeons who perform minimally-invasive prostatectomy took part in a user-needs analysis to determine the potential benefits of an image guidance system after viewing the overlaid images. All surgeons stated that the development would be useful at key stages of the surgery and could help to improve the learning curve of the procedure and improve functional and oncological outcomes. Establishing the clinical need in this way is a vital early step in development of an AR guidance system. We have also identified relevant anatomy from preoperative MRI. Further work will be aimed at automated registration to account for tissue deformation during the procedure, using a combination of transrectal ultrasound and stereoendoscopic video.

  5. Information Security – Guidance for Manually Completing the Information Security Awareness Training

    Science.gov (United States)

    The purpose of this guidance is to provide an alternative manual process for disseminating EPA Information Security Awareness Training (ISAT) materials and collecting results from EPA users who elect to complete the ISAT manually.

  6. FDA Issues Final Guidance Clarifying FDA and EPA Jurisdiction over Mosquito-Related Products

    Science.gov (United States)

    FDA finalized guidance to provide information on FDA and EPA jurisdiction over the regulation of mosquito-related products intended to function as pesticides, including those products intended to function as pesticides

  7. Memo Clarifying Requirements and State Reporting Guidance to Transition to the Revised Total Coliform Rule

    Science.gov (United States)

    This memorandum provides guidance to primacy agencies with enforcement responsibility under the Safe Drinking Water Act (SDWA) concerning the requirements to transition public water systems (PWSs) from the Total Coliform Rule (TCR) to the RTCR

  8. 76 FR 789 - Guidance for Industry and Food and Drug Administration Staff; Section 905(j) Reports...

    Science.gov (United States)

    2011-01-06

    ... Family Smoking Prevention and Tobacco Control Act (the Tobacco Control Act) (Pub. L. 111-31). Section 905... . SUPPLEMENTARY INFORMATION: I. Background FDA is announcing the availability of a guidance that provides...

  9. Federal Building Metering Guidance (per 42 U.S.C. 8253(e), Metering of Energy Use)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-11-01

    Guidance defines which federal buildings are appropriate to meter, provides metering prioritization recommendations for agencies with limited resources, and discusses the requirement for agencies to submit metering implementation plans to the U.S. Department of Energy.

  10. Draft Guidance on EPA’s Section 8(a) Information Gathering Rule on Nanomaterials in Commerce

    Science.gov (United States)

    This guidance provides answers to questions the Agency has received from manufacturers (includes importers) and processors of certain chemical substances when they are manufactured or processed at the nanoscale as described in the final rule.

  11. Expanded Guidance for NASA Systems Engineering. Volume 1: Systems Engineering Practices

    Science.gov (United States)

    Hirshorn, Steven R.

    2016-01-01

    This document is intended to provide general guidance and information on systems engineering that will be useful to the NASA community. It provides a generic description of Systems Engineering (SE) as it should be applied throughout NASA. A goal of the expanded guidance is to increase awareness and consistency across the Agency and advance the practice of SE. This guidance provides perspectives relevant to NASA and data particular to NASA. This expanded guidance should be used as a companion for implementing NPR 7123.1, Systems Engineering Processes and Requirements, the Rev 2 version of SP-6105, and the Center-specific handbooks and directives developed for implementing systems engineering at NASA. It provides a companion reference book for the various systems engineering-related training being offered under NASA's auspices.

  12. 76 FR 6622 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Science.gov (United States)

    2011-02-07

    .... Electronic Access Persons interested in obtaining a copy of the guidance may do so by using the Internet. A... the SUPPLEMENTARY INFORMATION section for information on electronic access to the guidance. Submit... determine whether to amend the guidance document. II. Significance of Guidance The guidance is being issued...

  13. Integrated Closure and Monitoring Plan for the Area 3 and Area 5 Radioactive Waste Management Sites at the Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    S. E. Rawlinson

    2001-09-01

    Bechtel Nevada (BN) manages two low-level Radioactive Waste Management Sites (RWMSs) (one site is in Area 3 and the other is in Area 5) at the Nevada Test Site (NTS) for the U.S. Department of Energy's (DOE's) National Nuclear Security Administration Nevada Operations Office (NNSA/NV). The current DOE Order governing management of radioactive waste is 435.1. Associated with DOE Order 435.1 is a Manual (DOE M 435.1-1) and Guidance (DOE G 435.1-1). The Manual and Guidance specify that preliminary closure and monitoring plans for a low-level waste (LLW) management facility be developed and initially submitted with the Performance Assessment (PA) and Composite Analysis (CA) for that facility. The Manual and Guidance, and the Disposal Authorization Statement (DAS) issued for the Area 3 RWMS further specify that the preliminary closure and monitoring plans be updated within one year following issuance of a DAS. This Integrated Closure and Monitoring Plan (ICMP) fulfills both requirements. Additional updates will be conducted every third year hereafter. This document is an integrated plan for closing and monitoring both RWMSs, and is based on guidance issued in 1999 by the DOE for developing closure plans. The plan does not follow the format suggested by the DOE guidance in order to better accommodate differences between the two RWMSs, especially in terms of operations and site characteristics. The modification reduces redundancy and provides a smoother progression of the discussion. The closure and monitoring plans were integrated because much of the information that would be included in individual plans is the same, and integration provides efficient presentation and program management. The ICMP identifies the regulatory requirements, describes the disposal sites and the physical environment where they are located, and defines the approach and schedule for both closing and monitoring the sites.

  14. High-Quality See-Through Surgical Guidance System Using Enhanced 3-D Autostereoscopic Augmented Reality.

    Science.gov (United States)

    Zhang, Xinran; Chen, Guowen; Liao, Hongen

    2017-08-01

    Precise minimally invasive surgery (MIS) has significant advantages over traditional open surgery in clinic. Although pre-/intraoperative diagnosis images can provide necessary guidance for therapy, hand-eye discoordination occurs when guidance information is displayed away from the surgical area. In this study, we introduce a real three-dimensional (3-D) see-through guidance system for precision surgery. To address the resolution and viewing angle limitation as well as the accuracy degradation problems of autostereoscopic 3-D display, we design a high quality and high accuracy 3-D integral videography (IV) medical image display method. Furthermore, a novel see-through microscopic device is proposed to assist surgeons with the superimposition of real 3-D guidance onto the surgical target is magnified by an optical visual magnifier module. Spatial resolutions of 3-D IV image in different depths have been increased 50%∼70%, viewing angles of different image sizes have been increased 9%∼19% compared with conventional IV display methods. Average accuracy of real 3-D guidance superimposed on surgical target was 0.93 mm ± 0.41 mm. Preclinical studies demonstrated that our system could provide real 3-D perception of anatomic structures inside the patient's body. The system showed potential clinical feasibility to provide intuitive and accurate in situ see-through guidance for microsurgery without restriction on observers' viewing position. Our system can effectively improve the precision and reliability of surgical guidance. It will have wider applicability in surgical planning, microscopy, and other fields.

  15. Asbestos-Containing Materials in School Buildings: A Guidance Document. Part 2.

    Science.gov (United States)

    Sawyer, Robert N.; Spooner, Charles M.

    Part 2 of the Environmental Protection Agency (EPA) guidance manuals consists of more detailed information on asbestos identification and control methods. Available information on sprayed asbestos-containing materials in buildings is summarized. Guidelines are presented for the detection and monitoring, removal or encapsulation, and disposal of…

  16. 12 CFR Appendix A to Part 1720 - Policy Guidance; Minimum Safety and Soundness Requirements

    Science.gov (United States)

    2010-01-01

    ..., measurement, monitoring, and management of market risk. The Enterprise should: i. Establish and implement... credit quality. II. Balance sheet growth and management. III. Market risk. IV. Information technology. V... risks to an Enterprise. The minimum supervisory requirements of the Policy Guidance also reflect the...

  17. Regulatory Advocacy Update: ASPS Comments in Response to the FDA Draft Guidance Documents on Human Cell and Tissue Products.

    Science.gov (United States)

    Rubin, J Peter; D'Amico, Richard A; Rodriguez, Ricardo; Coleman, Sydney R; Cederna, Paul; Glasberg, Scot; Neumeister, Michael; Song, David H; Butler, Charles; Hume, Keith M

    2017-02-09

    The Food and Drug Administration (FDA) released draft guidance documents on Human Cells, Tissues, and Cellular and Tissue-Based Products (HCT/P) Regulations. These proposed guidance documents can impact the practice of plastic surgery in the area of tissue grafting procedures. This article describes the relevant issues in these draft guidance documents, and presents the comments provided to the FDA by the American Society of Plastic Surgeons (ASPS).

  18. Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals

    OpenAIRE

    Todde, Sergio; Stopar, Tanja; Mikolajczak, Renata; Farstad, Brit; Elsinga, Philip; Westera, Gerrit; Faivre-Chauvet, Alan; Meyer, Geerd; Penuelas, Ivan; Decristoforo, Clemens

    2010-01-01

    This guidance is meant as a guidance to Part B of the EANM ?Guidelines on Good Radiopharmacy Practice (GRPP)? issued by the Radiopharmacy Committee of the EANM (see www.eanm.org), covering the small-scale ?in house? preparation of radiopharmaceuticals which are not kit procedures. The aim is to provide more detailed and practice-oriented guidance to those who are involved in the small-scale preparation of, for example, PET, therapeutic or other radiopharmaceuticals which are not intended for ...

  19. Waste treatability guidance program. User`s guide. Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Toth, C.

    1995-12-21

    DOE sites across the country generate and manage radioactive, hazardous, mixed, and sanitary wastes. It is necessary for each site to find the technologies and associated capacities required to manage its waste. One role of DOE HQ Office of Environmental Restoration and Waste Management is to facilitate the integration of the site- specific plans into coherent national plans. DOE has developed a standard methodology for defining and categorizing waste streams into treatability groups based on characteristic parameters that influence waste management technology needs. This Waste Treatability Guidance Program automates the Guidance Document for the categorization of waste information into treatability groups; this application provides a consistent implementation of the methodology across the National TRU Program. This User`s Guide provides instructions on how to use the program, including installations instructions and program operation. This document satisfies the requirements of the Software Quality Assurance Plan.

  20. Guidance for Environmental Mangement Science and Technology Roadmapping

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Brent Wayne

    2001-02-01

    Science and technology roadmapping is a planning process to help identify technical capabilities needed for both project- and program-level cleanup efforts, map them into technology alternatives, and develop plans to ensure that the required scientific knowledge and tools will be available when needed. Application of science and technology roadmapping within Invironmental Management (EM) requires significant flexibility to accommodate the variations between different projects and programs and the different levels of roadmapping application. The author has provided direct support to EM’s Office of Science and Technology (OST) in the development of draft guidance for science and technology roadmapping in EM. This paper provides a summary of this guidance and a synopsis of lessons learned from the application of roadmapping to a number of EM projects and programs.

  1. Guidance on the environmental risk assessment of genetically modified plants

    DEFF Research Database (Denmark)

    Bartsch, Detlef; Chueca, Cristina; De-Schrijver, Adinda

    This document provides guidance for the environmental risk assessment (ERA) of genetically modified (GM) plants submitted within the framework of Regulation (EC) No. 1829/2003 on GM food and feed or under Directive 2001/18/EC on the deliberate release into the environment of genetically modified...... organisms (GMOs). This document provides guidance for assessing potential effects of GM plants on the environment and the rationales for the data requirements for a comprehensive ERA of GM plants. The ERA should be carried out on a case-by-case basis, following a step-by-step assessment approach...... risk evaluation. The scientific Panel on Genetically Modified Organisms (of the European Food Safety Authority (EFSA GMO Panel) considers seven specific areas of concern to be addressed by applicants and risk assessors during the ERA (1) persistence and invasiveness of the GM plant , or its compatible...

  2. The World Health Organization's safe abortion guidance document.

    Science.gov (United States)

    Van Look, Paul F A; Cottingham, Jane

    2013-04-01

    We discuss the history of the World Health Organization's (WHO's) development of guidelines for governments on providing safe abortion services, which WHO published as Safe Abortion: Technical and Policy Guidance for Health Systems in 2003 and updated in 2012. We show how the recognition of the devastating impact of unsafe abortion on women's health and survival, the impetus of the International Conference on Population and Development and its five-year follow-up, and WHO's progressive leadership at the end of the century enabled the organization to elaborate guidance on providing safe abortion services. Guideline formulation involved extensive review of published evidence, an international technical expert meeting to review the draft document, and a protracted in-house review by senior WHO management.

  3. Technology guidance for safeguards information management

    Energy Technology Data Exchange (ETDEWEB)

    Manatt, D.R. [Lawrence Livermore National Lab., CA (United States); Howell, J.A. [Los Alamos National Lab., NM (United States); Steinmaus, K.; St. Pierre, D. [Pacific Northwest Lab., Richland, WA (United States); Deland, S.M.; Vandewart, R. [Sandia National Labs., Albuquerque, NM (United States)

    1994-09-01

    The Safeguards Information Management Systems project, SIMS, seeks to provide information access tools to the IAEA to assist in implementation of enhanced safeguards. The Technology and Systems Group advises the SIMS project in the selection of hardware and software, the integration of system components, and the evaluation of realistic information management approaches. The group`s guidance has led to reevaluation of the system hardware choices, visual data storage methods, and geographical data sources. Consultation with the Agency has resulted in a major realignment of the effort towards providing information access on Networked Microsoft Windows desk top computers rather than separate SUN workstations. The manner in which imagery is stored and presented is another developing area. Initial systems delivered to the Agency relied on analogue video disc recorders and VCRs. Future systems will store and manipulate digital images. The initial source of map data for the workstation was analogue video discs from the US Defense Mapping Agency. Many of these maps are restricted in their distribution, therefore additional map data sources were developed. The Technology map data sources were developed. The Technology and Systems Group`s efforts to steer a clear course through this ever changing mine-field is described.

  4. Guidance and Control Software Project Data - Volume 3: Verification Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the verification documents from the GCS project. Volume 3 contains four appendices: A. Software Verification Cases and Procedures for the Guidance and Control Software Project; B. Software Verification Results for the Pluto Implementation of the Guidance and Control Software; C. Review Records for the Pluto Implementation of the Guidance and Control Software; and D. Test Results Logs for the Pluto Implementation of the Guidance and Control Software.

  5. Guidance and Control Software Project Data - Volume 1: Planning Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the planning documents from the GCS project. Volume 1 contains five appendices: A. Plan for Software Aspects of Certification for the Guidance and Control Software Project; B. Software Development Standards for the Guidance and Control Software Project; C. Software Verification Plan for the Guidance and Control Software Project; D. Software Configuration Management Plan for the Guidance and Control Software Project; and E. Software Quality Assurance Activities.

  6. Monitoring trail conditions: New methodological considerations

    Science.gov (United States)

    Marion, Jeffrey L.; Leung, Yu-Fai; Nepal, Sanjay K.

    2006-01-01

    The U.S. National Park Service (NPS) accommodates nearly 300 million visitors per year, visitation that has the potential to produce negative effects on fragile natural and cultural resources. The policy guidance from the NPS Management Policies recognizes the legitimacy of providing opportunities for public enjoyment of parks while acknowledging the need for managers to “seek ways to avoid, or to minimize to the greatest degree practicable, adverse impacts on park resources and values” (NPS 2001). Thus, relative to visitor use, park managers must evaluate the types and extents of resource impacts associated with recreational activities, and determine to what extent they are unacceptable and constitute impairment. Visitor impact monitoring programs can assist managers in making objective evaluations of impact acceptability and impairment and in selecting effective impact management practices by providing quantitative documentation of the types and extent of recreationrelated impacts on natural resources. Monitoring programs are explicitly authorized in Section 4.1 of the Management Policies: Natural systems in the national park system, and the human influences upon them, will be monitored to detect change. The Service will use the results of monitoring and research to understand the detected change and to develop appropriate management actions.

  7. Significant Guidance Issued by the Federal Transit Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  8. Significant Guidance Issued by the Federal Highway Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  9. Significant Guidance Issued by the Federal Motor Carrier Safety Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  10. Significant Guidance Issued by the Federal Aviation Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  11. Raw material monitoring assists companies. German Mineral Resources Agency at BGR provides information on global developments in resource markets; Rohstoffmonitoring hilft Unternehmen. Die Deutsche Rohstoffagentur in der BGR informiert ueber weltweite Entwicklungen auf den Rohstoffmaerkten

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-05-15

    Germany is dependent on imports for its metalliferous natural resources. Although prices have been declining significantly in recent months, numerous raw materials such as platinum, cobalt and rare earth elements continue to be exposed to price and supply risks. To ensure that German industry can respond better to this situation in their procurement activities, the German Mineral Resources Agency (DERA) at BGR has developed a raw material monitoring system on behalf of the German government. DERA experts have con figured a screening method for the early identification of possible procurement risks. This is the platform which enables German companies to gain the specific advice they require. All of the most important information on this issue is bundled within DERA 's internet portal (www.deutsche-rohstoffagentur.de). BGR also provides its expertise in other important fields with great societal relevance. BGR has been advising the national commission on ''Storage of High-level Radioactive Waste'' since 2014. Due to their comprehensive research activities in the field of radioactive waste disposal, BGR scientists are important technical experts to which the commission can turn to for geological information and advice.

  12. The impact of clinical trial monitoring approaches on data integrity and cost--a review of current literature.

    Science.gov (United States)

    Olsen, Rasmus; Bihlet, Asger Reinstrup; Kalakou, Faidra; Andersen, Jeppe Ragnar

    2016-04-01

    Monitoring is a costly requirement when conducting clinical trials. New regulatory guidance encourages the industry to consider alternative monitoring methods to the traditional 100 % source data verification (SDV) approach. The purpose of this literature review is to provide an overview of publications on different monitoring methods and their impact on subject safety data, data integrity, and monitoring cost. The literature search was performed by keyword searches in MEDLINE and hand search of key journals. All publications were reviewed for details on how a monitoring approach impacted subject safety data, data integrity, or monitoring costs. Twenty-two publications were identified. Three publications showed that SDV has some value for detection of not initially reported adverse events and centralized statistical monitoring (CSM) captures atypical trends. Fourteen publications showed little objective evidence of improved data integrity with traditional monitoring such as 100 % SDV and sponsor queries as compared to reduced SDV, CSM, and remote monitoring. Eight publications proposed a potential for significant cost reductions of monitoring by reducing SDV without compromising the validity of the trial results. One hundred percent SDV is not a rational method of ensuring data integrity and subject safety based on the high cost, and this literature review indicates that reduced SDV is a viable monitoring method. Alternative methods of monitoring such as centralized monitoring utilizing statistical tests are promising alternatives but have limitations as stand-alone tools. Reduced SDV combined with a centralized, risk-based approach may be the ideal solution to reduce monitoring costs while improving essential data quality.

  13. SUPPORTING THE INDUSTRY BY DEVELOPING A DESIGN GUIDANCE FOR COMPUTER-BASED PROCEDURES FOR FIELD WORKERS

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna; LeBlanc, Katya

    2017-06-01

    The paper-based procedures currently used for nearly all activities in the commercial nuclear power industry have a long history of ensuring safe operation of the plants. However, there is potential to greatly increase efficiency and safety by improving how the human interacts with the procedures, which can be achieved through the use of computer-based procedures (CBPs). A CBP system offers a vast variety of improvements, such as context driven job aids, integrated human performance tools and dynamic step presentation. As a step toward the goal of improving procedure use performance, the U.S. Department of Energy Light Water Reactor Sustainability Program researchers, together with the nuclear industry, have been investigating the possibility and feasibility of replacing current paper-based procedures with CBPs. The main purpose of the CBP research conducted at the Idaho National Laboratory was to provide design guidance to the nuclear industry to be used by both utilities and vendors. After studying existing design guidance for CBP systems, the researchers concluded that the majority of the existing guidance is intended for control room CBP systems, and does not necessarily address the challenges of designing CBP systems for instructions carried out in the field. Further, the guidance is often presented on a high level, which leaves the designer to interpret what is meant by the guidance and how to specifically implement it. The authors developed a design guidance to provide guidance specifically tailored to instructions that are carried out in the field based.

  14. Guidance of magnetic space tug

    Science.gov (United States)

    Fabacher, Emilien; Lizy-Destrez, Stéphanie; Alazard, Daniel; Ankersen, Finn; Profizi, Alexandre

    2017-07-01

    Magnetic tugging of a target satellite without thrust capacity can be interesting in various contexts, as for example End-Of-Life management, or to complete launchers capabilities. The aim is to gradually modify the orbit of the target by constantly exerting on it a magnetic force. To do so, the chaser is assumed equipped with a steerable magnetic dipole, able to create both forces and torques on the magnetic torque rods carried by the target. The chaser is also supposed to carry electric thrusters, creating a continuous force which modifies the orbit of the whole formation composed of chaser and target. The relative motions of both satellites are derived, in order to assess the feasibility of such a concept. Relative configuration (attitudes and position) trajectories are derived, which are compliant with the dynamics, and enable the chaser to tug the target. Considering targets in Low Earth Orbit (LEO), the magnetic field of the Earth is taken into account, modeled by the International Geomagnetic Reference Field (IGRF). The position of the magnetic torque rod of the target may not be located at its center of mass. This lever-arm is taken into account in the dynamics. As for every Electro-Magnetic Formation Flight concept developed in the literature, satellites involved in magnetic tugging are constantly subjected to torques, created by the Earth magnetic field and by the magnetic fields created by the other satellites in the formation. In this study, the solution chosen to face this problem is to take into account the attitude equilibrium of the satellites early in the guidance phase, in order to avoid having to wave the dipole, as it is generally done. Promising results are presented for different types of orbit, showing that the concept could be feasible in many different scenarios.

  15. Warehouse multipoint temperature and humidity monitoring system design based on Kingview

    Science.gov (United States)

    Ou, Yanghui; Wang, Xifu; Liu, Jingyun

    2017-04-01

    Storage is the key link of modern logistics. Warehouse environment monitoring is an important part of storage safety management. To meet the storage requirements of different materials, guarantee their quality in the greatest extent, which has great significance. In the warehouse environment monitoring, the most important parameters are air temperature and relative humidity. In this paper, a design of warehouse multipoint temperature and humidity monitoring system based on King view, which realizes the multipoint temperature and humidity data real-time acquisition, monitoring and storage in warehouse by using temperature and humidity sensor. Also, this paper will take the bulk grain warehouse as an example and based on the data collected in real-time monitoring, giving the corresponding expert advice that combined with the corresponding algorithm, providing theoretical guidance to control the temperature and humidity in grain warehouse.

  16. Image Guidance Technologies for Interventional Pain Procedures: Ultrasound, Fluoroscopy, and CT.

    Science.gov (United States)

    Wang, Dajie

    2018-01-26

    to fluoroscopy. However, further studies are required to prove the efficacy of ultrasound-guided transforaminal epidural injections. SI joint is unique due to its multiplanar orientation, irregular joint gap, partial ankylosis, and thick dorsal and interosseous ligament. Therefore, it can be difficult to access the joint space with fluoroscopic guidance and ultrasound guidance. CT scan, with its cross-sectional images, can identify posterior joint gap, is most likely the best guidance technology for this intervention. Intercostal nerves lie in the subcostal grove close to the plural space. Significant risk of pneumothorax is associated with intercostal blocks. Ultrasound can provide visualization of ribs and pleura. Therefore, it may improve the accuracy of the injection and reduce the risk of pneumothorax. At present time, most pain specialists are familiar with fluoroscopic guidance techniques, and fluoroscopic machines are readily available in the pain clinics. In the contrast, CT guidance can only be performed in specially equipped facilities. Ultrasound machine is generally portable and inexpensive in comparison to CT scanner and fluoroscopic machine. As pain specialists continue to improve their patient care, ultrasound and CT guidance will undoubtedly be incorporated more into the pain management practice. This review is based on a paucity of clinical evidence to compare these guidance technologies; clearly, more clinical studies is needed to further elucidate the pro and cons of each guidance method for various pain management interventions.

  17. USACE Fiscal Year 2001, Consolidated Command Guidance

    National Research Council Canada - National Science Library

    2000-01-01

    The CCG is a single document which for the past several years has presented a summary of USACE's strategic direction, resource guidance, and performance requirements for the upcoming fiscal year and outyears...

  18. Children and Crises: A Classroom Guidance Approach.

    Science.gov (United States)

    Allan, John; Anderson, Eileen

    1986-01-01

    Describes a guidance project designed to help children develop skills to cope with crisis. Discusses understanding the crisis, being aware of changing thoughts and feelings, and using coping strategies and behaviors. (ABB)

  19. RCRA Programmatic Information Policy and Guidance

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes program policy and guidance documents that are used by the EPA regions, states, tribes and private parties to implement the hazardous waste...

  20. Responsible Purchasing Network - Sustainable Purchasing Guidance Profile

    Science.gov (United States)

    To help you find the resource that is right for your organization, EPA conducted a scan of the landscape and developed summary profiles of some of the leading sources of sustainable purchasing guidance around the globe.

  1. European Union Sustainable Purchasing Guidance Profile

    Science.gov (United States)

    To help you find the resource that is right for your organization, EPA conducted a scan of the landscape and developed summary profiles of some of the leading sources of sustainable purchasing guidance around the globe.

  2. Hydrostatic Reduction of Intussusception under Ultrasound Guidance

    African Journals Online (AJOL)

    Hydrostatic Reduction of Intussusception under Ultrasound Guidance: An Initial Experience in a Developing Country. O M Atalabi, O O Ogundoyin, D I Ogunlana, O M Onasanya, T A Lawal, A S Olarinoye ...

  3. Marriage guidance counselling in a group practice.

    Science.gov (United States)

    Marsh, G N; Barr, J

    1975-01-01

    This paper describes the work of a marriage guidance cousellor in a group-practice centre. The considerable advantages to patient, doctor, and counsellor of her close association with the primary medical care team are discussed.

  4. Recent advances in remote coal mining machine sensing, guidance, and teleoperation

    Energy Technology Data Exchange (ETDEWEB)

    Ralston, J.C.; Hainsworth, D.W.; Reid, D.C.; Anderson, D.L.; McPhee, R.J. [CSIRO Exploration & Minerals, Kenmore, Qld. (Australia)

    2001-10-01

    Some recent applications of sensing, guidance and telerobotic technology in the coal mining industry are presented. Of special interest is the development of semi or fully autonomous systems to provide remote guidance and communications for coal mining equipment. The use of radar and inertial based sensors are considered in an attempt to solve the horizontal and lateral guidance problems associated with mining equipment automation. Also described is a novel teleoperated robot vehicle with unique communications capabilities, called the Numbat, which is used in underground mine safety and reconnaissance missions.

  5. a Modified Cellular Automaton Model for Ring Road Traffic with Velocity Guidance

    Science.gov (United States)

    Mei, C. Q.; Huang, H. J.; Tang, T. Q.

    We present a modified cellular automaton model to study the traffic flow on a signal controlled ring road with velocity guidance. The velocity guidance is such a strategy that when vehicles approach the traffic light, suggested velocities are provided for avoiding the vehicles' sharp brakes in front of red light. Simulation results show that this strategy may significantly reduce the vehicles' stopping rate and the effect size is dependent upon the traffic density, the detector position, the signal's cycle time and the obedience rate of vehicles to the guidance.

  6. Integration of structural health monitoring solutions onto commercial aircraft via the Federal Aviation Administration structural health monitoring research program

    Science.gov (United States)

    Swindell, Paul; Doyle, Jon; Roach, Dennis

    2017-02-01

    The Federal Aviation Administration (FAA) started a research program in structural health monitoring (SHM) in 2011. The program's goal was to understand the technical gaps of implementing SHM on commercial aircraft and the potential effects on FAA regulations and guidance. The program evolved into a demonstration program consisting of a team from Sandia National Labs Airworthiness Assurance NDI Center (AANC), the Boeing Corporation, Delta Air Lines, Structural Monitoring Systems (SMS), Anodyne Electronics Manufacturing Corp (AEM) and the FAA. This paper will discuss the program from the selection of the inspection problem, the SHM system (Comparative Vacuum Monitoring-CVM) that was selected as the inspection solution and the testing completed to provide sufficient data to gain the first approved use of an SHM system for routine maintenance on commercial US aircraft.

  7. Human Systems Integration: Unmanned Aircraft Control Station Certification Plan Guidance

    Science.gov (United States)

    2005-01-01

    This document provides guidance to the FAA on important human factors considerations that can be used to support the certification of a UAS Aircraft Control Station (ACS). This document provides a synopsis of the human factors analysis, design and test activities to be performed to provide a basis for FAA certification. The data from these analyses, design activities, and tests, along with data from certification/qualification tests of other key components should be used to establish the ACS certification basis. It is expected that this information will be useful to manufacturers in developing the ACS Certification Plan,, and in supporting the design of their ACS.

  8. Rural transit emergency planning guidance.

    Science.gov (United States)

    2008-07-01

    Providing safe, reliable transportation has long been a priority at all levels of the transit industry including the Federal Transit Administration (FTA), California Department of Transportation (Caltrans) and individual transit providers. Over the l...

  9. Minimum-Jerk Guidance for Lunar Lander

    Science.gov (United States)

    Uchiyama, Kenji; Shimada, Yuzo; Ogawa, Kazuhiro

    An optimal guidance law derived by solving the minimum-acceleration problem has been reported for control of a lunar lander. In our past work, the guidance law was proved to enable vertical/soft landing. However, it was not robust against disturbance because there was a constraint condition relative to initial conditions in order to satisfy optimality. Therefore, if the constraint is not satisfied, the lunar lander must be controlled to track the reference trajectory generated by the optimal guidance law in order to be robust against disturbance. The control system makes the landing system complex and fuel consumption is increased in comparison to a guidance law without tracking control. Consequently, this study restructures the optimal control problem as a minimum-jerk problem to solve it. Jerk is a physical quantity defined as the time derivative of acceleration. The new optimal guidance law obtained has no constraints on the initial conditions. The results of computer simulation confirm the usefulness of the proposed guidance law.

  10. Transmission line environmental assessment guidance document

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, J.; Pentecost, E.; Muzzarelli, J.

    1994-01-01

    Since 1939, U.S. utility companies have been required to obtain a Presidential Permit to construct electric transmission lines that cross a U.S. border and connect with a foreign utility. The purpose of this document is to provide Presidential Permit applicants with two types of guidance: (1) on the type of environmental and project descriptive information needed to assess the potential impacts of the proposed and alternative actions and (2) on compliance with applicable federal and state regulations. The main three chapters present information on the purpose and content of this document (Chapter 1); legislative, regulatory, and consultation requirements for transmission line interconnect projects (Chapter 2); and identification of basic transmission system design parameters and environmental data requirements for analysis of potential impacts of the proposed action (Chapter 3). Chapter 3 also includes information on possible techniques or measures to mitigate impacts. Appendix A presents an overview of NEPA requirements and DOE`s implementing procedures. Appendix B summarizes information on legislation that may be applicable to transmission line projects proposed in Presidential Permit applications.

  11. Analysis and design of energy monitoring platform for smart city

    Science.gov (United States)

    Wang, Hong-xia

    2016-09-01

    The development and utilization of energy has greatly promoted the development and progress of human society. It is the basic material foundation for human survival. City running is bound to consume energy inevitably, but it also brings a lot of waste discharge. In order to speed up the process of smart city, improve the efficiency of energy saving and emission reduction work, maintain the green and livable environment, a comprehensive management platform of energy monitoring for government departments is constructed based on cloud computing technology and 3-tier architecture in this paper. It is assumed that the system will provide scientific guidance for the environment management and decision making in smart city.

  12. General RMP Guidance - Appendix E: Supplemental Risk Management Program Guidance for Ammonia Refrigeration Facilities

    Science.gov (United States)

    Additional information for food processors, food distributors, refrigerated warehouses, and any other facility with ammonia refrigeration system. Includes guidance on exemptions, threshold quantity, offsite consequence analysis.

  13. Practical research-based guidance for motor imagery practice in neurorehabilitation.

    Science.gov (United States)

    Bovend'eerdt, Thamar J H; Dawes, Helen; Sackley, Catherine; Wade, Derick T

    2012-01-01

    The purpose of this appraisal is to offer guidance to clinicians on applying motor imagery in neurorehabilitation and provide guidance to support this process. We used evidence from a variety of fields as well as clinical experience with motor imagery to develop guidance for employing motor imagery during neurorehabilitation. Motor imagery is a relatively new intervention for neurorehabilitation supported by evidence from areas such as cognitive neuroscience and sports psychology. Motor imagery has become a very popular intervention modality for clinicians but there is insufficient information available on how to administer it in clinical practice and make deliberate decisions during its application. We provide evidence-based guidance for employing motor imagery in neurorehabilitation and use the principles of motor learning as the framework for clinical application.

  14. Review of Research On Guidance for Recovery from Pitch Axis Upsets

    Science.gov (United States)

    Harrison, Stephanie J.

    2016-01-01

    A literature review was conducted to identify past efforts in providing control guidance for aircraft upset recovery including stall recovery. Because guidance is integrally linked to the intended function of aircraft attitude awareness and upset recognition, it is difficult, if not impossible, to consider these issues separately. This literature review covered the aspects of instrumentation and display symbologies for attitude awareness, aircraft upset recognition, upset and stall alerting, and control guidance. Many different forms of symbology have been investigated including, but not limited to, pitch scale depictions, attitude indicator icons, horizon symbology, attitude recovery arrows, and pitch trim indicators. Past research on different visual and alerting strategies that provide advisories, cautions, and warnings to pilots before entering an unusual attitude (UA) are also discussed. Finally, potential control guidance for recovery from upset or unusual attitudes, including approach-to-stall and stall conditions, are reviewed. Recommendations for future research are made.

  15. Framework for ecological monitoring on lands of Alaska National Wildlife Refuges and their partners

    Science.gov (United States)

    Woodward, Andrea; Beever, Erik A.

    2010-01-01

    National Wildlife Refuges in Alaska and throughout the U.S. have begun developing a spatially comprehensive monitoring program to inform management decisions, and to provide data to broader research projects. In an era of unprecedented rates of climate change, monitoring is essential to detecting, understanding, communicating and mitigating climate-change effects on refuge and other resources under the protection of U.S. Fish and Wildlife Service, and requires monitoring results to address spatial scales broader than individual refuges. This document provides guidance for building a monitoring program for refuges in Alaska that meets refuge-specific management needs while also allowing synthesis and summary of ecological conditions at the ecoregional and statewide spatial scales.

  16. Guidance for a radiological emergency exercise applied to the tabletop

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Moon; Khang, Byung Oui; Lee, Goan Yub; Lee, Jong Tai

    1998-02-01

    This document provides a guide for planning and conducting a tabletop for emergency exercise planners of state, local governments, and utilities of a nuclear facility to response the radiological emergency incidents. The organizations and their duties for the tabletop exercise were described in this guidance, which were composed of 3 time periods: First, the planning period is to fix the scale and milestone of the tabletop exercise. Second, the conduct period is to perform in accordance with a exercise scenario. Finally, the post-tabletop period is to prepare and distribute the final report. This guidance is intended as a reference tool to develop an integrated approach on the national emergency exercise plans. (author). 6 refs.

  17. Planning guidance for the Chemical Stockpile Emergency Preparedness Program

    Energy Technology Data Exchange (ETDEWEB)

    Shumpert, B.L.; Watson, A.P.; Sorensen, J.H. [and others

    1995-02-01

    This planning guide was developed under the direction of the U.S. Army and the Federal Emergency Management Agency (FEMA) which jointly coordinate and direct the development of the Chemical Stockpile Emergency Preparedness Program (CSEPP). It was produced to assist state, local, and Army installation planners in formulating and coordinating plans for chemical events that may occur at the chemical agent stockpile storage locations in the continental United States. This document provides broad planning guidance for use by both on-post and off-post agencies and organizations in the development of a coordinated plan for responding to chemical events. It contains checklists to assist in assuring that all important aspects are included in the plans and procedures developed at each Chemical Stockpile Disposal Program (CSDP) location. The checklists are supplemented by planning guidelines in the appendices which provide more detailed guidance regarding some issues. The planning guidance contained in this document will help ensure that adequate coordination between on-post and off-post planners occurs during the planning process. This planning guide broadly describes an adequate emergency planning base that assures that critical planning decisions will be made consistently at every chemical agent stockpile location. This planning guide includes material drawn from other documents developed by the FEMA, the Army, and other federal agencies with emergency preparedness program responsibilities. Some of this material has been developed specifically to meet the unique requirements of the CSEPP. In addition to this guidance, other location-specific documents, technical studies, and support studies should be used as needed to assist in the planning at each of the chemical agent stockpile locations to address the specific hazards and conditions at each location.

  18. Prosthodontic Management of Segmental Mandibulectomy Patient with Guidance Appliance and Overlay Denture

    OpenAIRE

    Aruna, U.; Thulasingam, C.

    2012-01-01

    Patients who undergo segmental or hemi-mandibulectomy suffer from various postoperative problems in esthetics and function. The solution to such problem is providing a mandibular guidance appliance to correct mandibular deviation to resected side due to loss of muscle action on the affected side. This article describes the treatment of a female patient who underwent segmental mandibulectomy on right side secondary to adenoid cystic carcinoma of the base of tongue. An acrylic guidance applianc...

  19. EFSA Guidance Document on the risk assessment of plant protection products on bees (Apis mellifera, Bombus spp. and solitary bees)

    NARCIS (Netherlands)

    Arnold, G.; Boesten, J.J.T.I.; Clook, M.

    2013-01-01

    The Guidance Document is intended to provide guidance for notifiers and authorities in the context of the review of plant protection products (PPPs) and their active substances under Regulation (EC) 1107/2009. The scientific opinion on the science behind the development of a risk assessment of plant

  20. Military Base Realignments and Closures: More Guidance and Information Needed to Take Advantage of Opportunities to Consolidate Training

    Science.gov (United States)

    2016-02-01

    Consolidate Training Report to Congressional Committees February 2016 GAO-16-45 United States Government Accountability Office...REALIGNMENTS AND CLOSURES More Guidance and Information Needed to Take Advantage of Opportunities to Consolidate Training Why GAO Did This Study...recommendations in any future BRAC rounds, GAO recommends that DOD provide additional guidance for consolidating training and reporting BRAC costs and

  1. 76 FR 78670 - Draft Guidance for Industry and Food and Drug Administration Staff; Evaluation of Sex Differences...

    Science.gov (United States)

    2011-12-19

    ... Staff; Evaluation of Sex Differences in Medical Device Clinical Studies; Availability AGENCY: Food and... the availability of the draft guidance entitled ``Evaluation of Sex Differences in Medical Device Clinical Studies.'' This document provides guidance on the study and evaluation of sex differences in...

  2. 75 FR 8968 - Draft Guidance for Industry on Adaptive Design Clinical Trials for Drugs and Biologics; Availability

    Science.gov (United States)

    2010-02-26

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Adaptive Design Clinical... current thinking on adaptive design clinical trials for drugs and biologics. It does not create or confer... entitled ``Adaptive Design Clinical Trials for Drugs and Biologics.'' The draft guidance provides sponsors...

  3. 77 FR 51814 - Draft Guidance for Industry on Generic Drug User Fee Amendments of 2012: Questions and Answers...

    Science.gov (United States)

    2012-08-27

    ... Amendments of 2012: Questions and Answers; Availability AGENCY: Food and Drug Administration, HHS. ACTION... draft guidance for industry entitled ``Generic Drug User Fee Amendments of 2012: Questions and Answers... information annually to FDA. This guidance is intended to provide answers to common questions from the generic...

  4. Technical bases and guidance for the use of composite soil sampling for demonstrating compliance with radiological release criteria

    Energy Technology Data Exchange (ETDEWEB)

    Vitkus, Timothy J. [Oak Ridge Institute for Science and Education, Oak Ridge, TN (United States). Independent Environmental Assessment and Verification Program

    2012-04-24

    This guidance provides information on methodologies and the technical bases that licensees should consider for incorporating composite sampling strategies into final status survey (FSS) plans. In addition, this guidance also includes appropriate uses of composite sampling for generating the data for other decommissioning site investigations such as characterization or other preliminary site investigations.

  5. Non-Participation in Guidance: An Opportunity for Development?

    Science.gov (United States)

    Thomsen, Rie

    2014-01-01

    This article discusses how new opportunities for guidance can emerge from an analysis of the interplay between the participation (or lack of participation) of the individuals in career guidance, and the career guidance practitioner's response. The article suggests critical psychology as a framework for career guidance research and presents…

  6. Monitoring and evaluation of spatially managed areas: A generic framework for implementation of ecosystem based marine management and its application

    DEFF Research Database (Denmark)

    Stelzenmüller, Vanessa; Breen, Patricia; Stamford, Tammy

    2013-01-01

    This study introduces a framework for the monitoring and evaluation of spatially managed areas (SMAs), which is currently being tested by nine European case studies. The framework provides guidance on the selection, mapping, and assessment of ecosystem components and human pressures, the evaluation......, such as the lack of operational objectives within SMAs, particularly for transnational cases, data access, and stakeholder involvement. Furthermore, the emerging challenges of integrating the framework assessment using scientific information with a structured governance research analysis based mainly...

  7. Application of an autonomous landing guidance system for civil and military aircraft

    Science.gov (United States)

    Franklin, Michael R.

    1995-06-01

    The ever increasing demand in the airline industry to reduce the costs associated with weather- related flight delays and cancellations has resulted in the need to be able to land an aircraft in low visibility. This has influenced research in recent years in the development of enhanced vision systems which allow all-weather operations, by providing both visual cues to the pilot and an independent integrity monitor. This research has focused on providing aircraft users with both enhanced performance and a cost effective landing solution with less dependence on ground systems, and has interested both the military and civil aircraft operator communities. The Autonomous Landing Guidance (ALG) system provides the capability to land in low visibility by displaying to the pilot an image of the real world without the need for an onboard Category II or III (CAT II/III) autoload system and without the associated ground facilities normally required. Besides the inherent advantage of saving the cost of expensive installations at airports, ALG also has the effect of inevitably solving the airport capacity problem, weather-related delays and diversions, and airport closures. Low visibility conditions typically cause the complete shutdown of smaller regional airports and reduces the availability of runways at major hubs, which creates a capacity problem to airlines.

  8. LEARNING SKILLS AS PART CONTENT MASTERY SERVICE IN GUIDANCE COUNSELING

    Directory of Open Access Journals (Sweden)

    Ida Umami

    2015-06-01

    Full Text Available Abstrack: This paper aimed to get the profile of efforts of guidance teachers in improving students’ learning skills. It is hoped that this papaer is useful for guidance teachers, subject teachers and student as well in improving their learning skills. The learning skill quality of the students was low while their learning problems were on medium level. Guidance given by guidance teachers to students to master learning skills was not yet optimal. There was cooperation among teachers and guidance teachers but it was still limited to physics teachers and it had skills came from both guidance teachers and students themselves. Keywords: guidance teachers, learning skill, students.

  9. Normalization in EDIP97 and EDIP2003: updated European inventory for 2004 and guidance towards a consistent use in practice

    DEFF Research Database (Denmark)

    Laurent, Alexis; Olsen, Stig Irving; Hauschild, Michael Zwicky

    2011-01-01

    regular updates. The study presents updated sets of normalization inventories, normalization references for the EDIP97/EDIP2003 methodology and guidance on their consistent use in practice. Materials and methods: The base year of the inventory is 2004; the geographical scope for the non-global impacts...... is limited to Europe. The emission inventory was collected from different publicly available databases and monitoring bodies. Where necessary, gaps were filled using extrapolations. A new approach for inventorizing specific groups of substances—non-methane volatile organic compounds and pesticides—was also...... developed. The resulting inventory was combined with the most updated sets of characterization factors for each impact category in the EDIP methodologies. Results and discussion: Normalization references are provided for global and non-global impact categories for the year 2004, and causes of variations...

  10. Priorities to Advance Monitoring of Ecosystem Services Using Earth Observation.

    Science.gov (United States)

    Cord, Anna F; Brauman, Kate A; Chaplin-Kramer, Rebecca; Huth, Andreas; Ziv, Guy; Seppelt, Ralf

    2017-06-01

    Managing ecosystem services in the context of global sustainability policies requires reliable monitoring mechanisms. While satellite Earth observation offers great promise to support this need, significant challenges remain in quantifying connections between ecosystem functions, ecosystem services, and human well-being benefits. Here, we provide a framework showing how Earth observation together with socioeconomic information and model-based analysis can support assessments of ecosystem service supply, demand, and benefit, and illustrate this for three services. We argue that the full potential of Earth observation is not yet realized in ecosystem service studies. To provide guidance for priority setting and to spur research in this area, we propose five priorities to advance the capabilities of Earth observation-based monitoring of ecosystem services. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Iraq liquid radioactive waste tanks maintenance and monitoring program plan.

    Energy Technology Data Exchange (ETDEWEB)

    Dennis, Matthew L.; Cochran, John Russell; Sol Shamsaldin, Emad (Iraq Ministry of Science and Technology)

    2011-10-01

    The purpose of this report is to develop a project management plan for maintaining and monitoring liquid radioactive waste tanks at Iraq's Al-Tuwaitha Nuclear Research Center. Based on information from several sources, the Al-Tuwaitha site has approximately 30 waste tanks that contain varying amounts of liquid or sludge radioactive waste. All of the tanks have been non-operational for over 20 years and most have limited characterization. The program plan embodied in this document provides guidance on conducting radiological surveys, posting radiation control areas and controlling access, performing tank hazard assessments to remove debris and gain access, and conducting routine tank inspections. This program plan provides general advice on how to sample and characterize tank contents, and how to prioritize tanks for soil sampling and borehole monitoring.

  12. 78 FR 56752 - Interim Staff Guidance Specific Environmental Guidance for Integral Pressurized Water Reactors...

    Science.gov (United States)

    2013-09-13

    ... activities associated with review of applications for ESPs, design certifications, and COLs by the Office of... comment on, draft Interim Staff Guidance (ISG) ESP/COL-ISG-027, ``Interim Staff Guidance Specific..., early site permits (ESPs), and combined licenses (COLs). DATES: Submit comments by October 15, 2013...

  13. Automated low-thrust guidance for the orbital maneuvering vehicle

    Science.gov (United States)

    Rose, Richard E.; Schmeichel, Harry; Shortwell, Charles P.; Werner, Ronald A.

    1988-01-01

    This paper describes the highly autonomous OMV Guidance Navigation and Control system. Emphasis is placed on a key feature of the design, the low thrust guidance algorithm. The two guidance modes, orbit change guidance and rendezvous guidance, are discussed in detail. It is shown how OMV will automatically transfer from its initial orbit to an arbitrary target orbit and reach a specified rendezvous position relative to the target vehicle.

  14. Environmental monitoring plan - environmental monitoring section. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Wilt, G.C. [ed.; Tate, P.J.; Brigdon, S.L. [and others

    1994-11-01

    This report presents the environmental monitoring plan for the Lawrence Livermore National Laboratory. A site characterization is provided along with monitoring and measurement techniques and quality assurance measures.

  15. International Scavenging for First Responder Guidance and Tools: IAEA Products

    Energy Technology Data Exchange (ETDEWEB)

    Stern, W. [Brookhaven National Lab. (BNL), Upton, NY (United States); Berthelot, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Bachner, K. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-05-05

    In fiscal years (FY) 2016 and 2017, with support from the U.S. Department of Homeland Security (DHS), Brookhaven National Laboratory (BNL) examined the International Atomic Energy Agency (IAEA) radiological emergency response and preparedness products (guidance and tools) to determine which of these products could be useful to U.S. first responders. The IAEA Incident and Emergency Centre (IEC), which is responsible for emergency preparedness and response, offers a range of tools and guidance documents for responders in recognizing, responding to, and recovering from radiation emergencies and incidents. In order to implement this project, BNL obtained all potentially relevant tools and products produced by the IAEA IEC and analyzed these materials to determine their relevance to first responders in the U.S. Subsequently, BNL organized and hosted a workshop at DHS National Urban Security Technology Laboratory (NUSTL) for U.S. first responders to examine and evaluate IAEA products to consider their applicability to the United States. This report documents and describes the First Responder Product Evaluation Workshop, and provides recommendations on potential steps the U.S. federal government could take to make IAEA guidance and tools useful to U.S. responders.

  16. GROUP GUIDANCE SERVICES MANAGEMENT OF BEHAVIORAL TECHNIC HOMEWORK MODEL

    Directory of Open Access Journals (Sweden)

    Juhri A M.

    2013-09-01

    Full Text Available Abstract: This simple paper describes the implementation of management guidance service groups using the model home visits behavioral techniques (behavior technic homework. The ideas outlined in this paper are intended to add insight for counselors in the management of the implementation of counseling services group that carried out effectively. This simple paper is expected to be used as reference studies in theoretical matters relating to the management guidance services group, for counselors to students both need guidance services and those who passively as they face various problems difficulties martial jar and obstacles in the achievement of learning , In general, this study aims to provide insight in particular in the development of social skills for students, especially the ability to communicate with the participants of the service (students more While specifically to encourage the development of feelings, thoughts, perceptions, insights and attitudes that support embodiments behavior Iebih creative and effective in improving communication skills both verbal and non-verbal for students. Keyword: counselor, counseling, group, student

  17. Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Sailer, Anna M., E-mail: anni.sailer@mumc.nl; Haan, Michiel W. de, E-mail: m.de.haan@mumc.nl; Graaf, Rick de, E-mail: r.de.graaf@mumc.nl; Zwam, Willem H. van, E-mail: w.van.zwam@mumc.nl [Maastricht University Medical Center, Department of Radiology (Netherlands); Schurink, Geert Willem H., E-mail: gwh.schurink@mumc.nl [Maastricht University Medical Center, Department of Surgery (Netherlands); Nelemans, Patricia J., E-mail: patty.nelemans@maastrichtuniversity.nl [Maastricht University Medical Centre, Department of Epidemiology (Netherlands); Wildberger, Joachim E., E-mail: j.wildberger@mumc.nl; Das, Marco, E-mail: m.das@mumc.nl [Maastricht University Medical Center, Department of Radiology (Netherlands)

    2015-04-15

    PurposeThis study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA).MethodsFusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography.ResultsAverage time needed for image coregistration was 5 ± 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 ± 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 ± 1.96 standard deviation).ConclusionsFluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety.

  18. Environmental regulatory guide for radiological effluent monitoring and environmental surveillance

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    Under the Atomic Energy Act of 1954, as amended, the US Department of Energy (DOE) is obligated to regulate its own activities so as to provide radiation protection for both workers and the public.'' Presidential Executive Order 12088, Federal Compliance with Pollution Control Standards,'' further requires the heads of executive agencies to ensure that all Federal facilities and activities comply with applicable pollution control standards and to take all actions necessary for the prevention, control, and abatement of environmental pollution. This regulatory guide describes the elements of an acceptable effluent monitoring and environmental surveillance program for DOE sites involving radioactive materials. These elements are applicable to all DOE and contractor activities for which the DOE exercises environmental, safety, and health responsibilities, and are intended to be applicable over the broad range of DOE facilities and sites. In situations where the high-priority elements may not provide sufficient coverage of a specific monitoring or surveillance topic, the document provides additional guidance. The high-priority elements are written as procedures and activities that should'' be performed, and the guidance is written as procedures and activities that should'' be performed. The regulatory guide both incorporates and expands on requirements embodied in DOE 5400.5 and DOE 5400.1. 221 refs., 2 figs., 6 tabs.

  19. Big Bayou Creek and Little Bayou Creek Watershed Monitoring Program

    Energy Technology Data Exchange (ETDEWEB)

    Kszos, L.A.; Peterson, M.J.; Ryon; Smith, J.G.

    1999-03-01

    Biological monitoring of Little Bayou and Big Bayou creeks, which border the Paducah Site, has been conducted since 1987. Biological monitoring was conducted by University of Kentucky from 1987 to 1991 and by staff of the Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) from 1991 through March 1999. In March 1998, renewed Kentucky Pollutant Discharge Elimination System (KPDES) permits were issued to the US Department of Energy (DOE) and US Enrichment Corporation. The renewed DOE permit requires that a watershed monitoring program be developed for the Paducah Site within 90 days of the effective date of the renewed permit. This plan outlines the sampling and analysis that will be conducted for the watershed monitoring program. The objectives of the watershed monitoring are to (1) determine whether discharges from the Paducah Site and the Solid Waste Management Units (SWMUs) associated with the Paducah Site are adversely affecting instream fauna, (2) assess the ecological health of Little Bayou and Big Bayou creeks, (3) assess the degree to which abatement actions ecologically benefit Big Bayou Creek and Little Bayou Creek, (4) provide guidance for remediation, (5) provide an evaluation of changes in potential human health concerns, and (6) provide data which could be used to assess the impact of inadvertent spills or fish kill. According to the cleanup will result in these watersheds [Big Bayou and Little Bayou creeks] achieving compliance with the applicable water quality criteria.

  20. USAID Colombia - Clearinghouse Monitor

    Data.gov (United States)

    US Agency for International Development — The Monitoring and Evaluation (M&E) Clearinghouse-Monitor is a web-based Information System that provides the Mission with information about the status and...

  1. Apnea monitor (image)

    Science.gov (United States)

    An apnea monitor checks the heart rate and respiration of the baby to make sure he or she is breathing properly. ... either one falls below normal levels, the apnea monitor beeps to notify the care provider that something ...

  2. Reducing Suspensions of Minority Males through a Group Guidance/Mentoring Intervention Program.

    Science.gov (United States)

    Campbell-Peralta, Pamela J.

    The 1990s are being labeled as the era of juvenile crime and violence. This program was developed, implemented, and targeted for adolescent minority males (n=25), in order to: (1) help identify at-risk students; (2) provide guidance; (3) provide strategies for academic success; (4) provide mentors; and (5) reduce the number of suspensions. Faculty…

  3. 40 CFR 130.4 - Water quality monitoring.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Water quality monitoring. 130.4... QUALITY PLANNING AND MANAGEMENT § 130.4 Water quality monitoring. (a) In accordance with section 106(e)(1.../quality control guidance. (b) The State's water monitoring program shall include collection and analysis...

  4. Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance

    Directory of Open Access Journals (Sweden)

    2006-10-01

    Full Text Available Abstract This guidance describes how the FDA evaluates patient-reported outcome (PRO instruments used as effectiveness endpoints in clinical trials. It also describes our current thinking on how sponsors can develop and use study results measured by PRO instruments to support claims in approved product labeling (see appendix point 1. It does not address the use of PRO instruments for purposes beyond evaluation of claims made about a drug or medical product in its labeling. By explicitly addressing the review issues identified in this guidance, sponsors can increase the efficiency of their endpoint discussions with the FDA during the product development process, streamline the FDA's review of PRO endpoint adequacy, and provide optimal information about the patient's perspective of treatment benefit at the time of product approval. A PRO is a measurement of any aspect of a patient's health status that comes directly from the patient (i.e., without the interpretation of the patient's responses by a physician or anyone else. In clinical trials, a PRO instrument can be used to measure the impact of an intervention on one or more aspects of patients' health status, hereafter referred to as PRO concepts, ranging from the purely symptomatic (response of a headache to more complex concepts (e.g., ability to carry out activities of daily living, to extremely complex concepts such as quality of life, which is widely understood to be a multidomain concept with physical, psychological, and social components. Data generated by a PRO instrument can provide evidence of a treatment benefit from the patient perspective. For this data to be meaningful, however, there should be evidence that the PRO instrument effectively measures the particular concept that is studied. Generally, findings measured by PRO instruments may be used to support claims in approved product labeling if the claims are derived from adequate and well-controlled investigations that use PRO

  5. Photochemical Assessment Monitoring Stations (PAMS)

    Data.gov (United States)

    U.S. Environmental Protection Agency — Photochemical Assessment Monitoring Stations (PAMS). This file provides information on the numbers and distribution (latitude/longitude) of air monitoring sites...

  6. Guidance for Human-system Interfaces to Automatic Systems

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, J.M.; Higgins, J.; Stephen Fleger; Valerie Barnes

    2010-09-27

    Automation is ubiquitous in modern complex systems, and commercial nuclear- power plants are no exception. Automation is applied to a wide range of functions, including monitoring and detection, situation assessment, response planning, and response implementation. Automation has become a 'team player' supporting personnel in nearly all aspects of system operation. In light of its increasing use and importance in new- and future-plants, guidance is needed to conduct safety reviews of the operator's interface with automation. The objective of this research was to develop such guidance. We first characterized the important HFE aspects of automation, including six dimensions: Levels, functions, processes, modes, flexibility, and reliability. Next, we reviewed literature on the effects of all of these aspects of automation on human performance, and on the design of human-system interfaces (HSIs). Then, we used this technical basis established from the literature to identify general principles for human-automation interaction and to develop review guidelines. The guidelines consist of the following seven topics: Automation displays, interaction and control, automation modes, automation levels, adaptive automation, error tolerance and failure management, and HSI integration.

  7. EPA guidance mental health care of migrants

    DEFF Research Database (Denmark)

    Bhugra, D; Gupta, S; Schouler-Ocak, M

    2014-01-01

    Migration is an increasingly commonplace phenomenon for a number of reasons. People migrate from rural to urban areas or across borders for reasons including economic, educational or political. There is increasing recent research evidence from many countries in Europe that indicates that migrants...... levels. In this guidance document, we briefly present the evidence and propose that specific measures must be taken to improve and manage psychiatric disorders experienced by migrants and their descendants. This improvement requires involvement at the highest level in governments. This is a guidance...

  8. Virtual Ultrasound Guidance for Inexperienced Operators

    Science.gov (United States)

    Caine, Timothy; Martin, David

    2012-01-01

    Medical ultrasound or echocardiographic studies are highly operator-dependent and generally require lengthy training and internship to perfect. To obtain quality echocardiographic images in remote environments, such as on-orbit, remote guidance of studies has been employed. This technique involves minimal training for the user, coupled with remote guidance from an expert. When real-time communication or expert guidance is not available, a more autonomous system of guiding an inexperienced operator through an ultrasound study is needed. One example would be missions beyond low Earth orbit in which the time delay inherent with communication will make remote guidance impractical. The Virtual Ultrasound Guidance system is a combination of hardware and software. The hardware portion includes, but is not limited to, video glasses that allow hands-free, full-screen viewing. The glasses also allow the operator a substantial field of view below the glasses to view and operate the ultrasound system. The software is a comprehensive video program designed to guide an inexperienced operator through a detailed ultrasound or echocardiographic study without extensive training or guidance from the ground. The program contains a detailed description using video and audio to demonstrate equipment controls, ergonomics of scanning, study protocol, and scanning guidance, including recovery from sub-optimal images. The components used in the initial validation of the system include an Apple iPod Classic third-generation as the video source, and Myvue video glasses. Initially, the program prompts the operator to power-up the ultrasound and position the patient. The operator would put on the video glasses and attach them to the video source. After turning on both devices and the ultrasound system, the audio-video guidance would then instruct on patient positioning and scanning techniques. A detailed scanning protocol follows with descriptions and reference video of each view along with

  9. Widening opportunities for career guidance

    DEFF Research Database (Denmark)

    Poulsen, Bo Klindt; Skovhus, Randi Boelskifte; Thomsen, Rie

    2017-01-01

    of career education in Danish schools. Based on a research and development project on career education, case analysis is used to explore research circles as a means for collaboration between researchers and practitioners. This analysis shows that research circles provide teachers with a space to reflect...

  10. Practical guidance for using rivaroxaban in patients with atrial fibrillation: balancing benefit and risk

    Directory of Open Access Journals (Sweden)

    Haas S

    2014-03-01

    Full Text Available Sylvia Haas,1 Christoph Bode,2 Bo Norrving,3 Alexander GG Turpie4 1Technical University Munich, Munich, Germany; 2Department of Cardiology and Angiology, University of Freiburg, Freiburg, Germany; 3Department of Clinical Neuroscience, Lund University Hospital, Lund, Sweden; 4Department of Medicine, McMaster University, Hamilton, Ontario, Canada Abstract: Rivaroxaban is a direct factor Xa inhibitor that is widely available to reduce the risk of stroke or systemic embolism in patients with nonvalvular atrial fibrillation and one or more risk factors for stroke. Rivaroxaban provides practical advantages compared with warfarin and other vitamin K antagonists, including a rapid onset of action, few drug interactions, no dietary interactions, a predictable anticoagulant effect, and no requirement for routine coagulation monitoring. However, questions have emerged relating to the responsible use of rivaroxaban in day-to-day clinical practice, including patient selection, dosing, treatment of patients with renal impairment, conversion from use of vitamin K antagonists to rivaroxaban and vice versa, coagulation tests, and management of patients requiring invasive procedures or experiencing bleeding or an ischemic event. This article provides practical recommendations relating to the use of rivaroxaban in patients with nonvalvular atrial fibrillation, based on clinical trial evidence, relevant guidelines, prescribing information, and the authors' clinical experience. Keywords: novel oral anticoagulants, direct factor Xa inhibitor, peri-interventional management, practical guidance, rivaroxaban, stroke prevention

  11. Functionality enhancement of industrialized optical fiber sensors and system developed for full-scale pavement monitoring.

    Science.gov (United States)

    Wang, Huaping; Liu, Wanqiu; He, Jianping; Xing, Xiaoying; Cao, Dandan; Gao, Xipeng; Hao, Xiaowei; Cheng, Hongwei; Zhou, Zhi

    2014-05-19

    Pavements always play a predominant role in transportation. Health monitoring of pavements is becoming more and more significant, as frequently suffering from cracks, rutting, and slippage renders them prematurely out of service. Effective and reliable sensing elements are thus in high demand to make prognosis on the mechanical properties and occurrence of damage to pavements. Therefore, in this paper, various types of functionality enhancement of industrialized optical fiber sensors for pavement monitoring are developed, with the corresponding operational principles clarified in theory and the performance double checked by basic experiments. Furthermore, a self-healing optical fiber sensing network system is adopted to accomplish full-scale monitoring of pavements. The application of optical fiber sensors assembly and self-healing network system in pavement has been carried out to validate the feasibility. It has been proved that the research in this article provides a valuable method and meaningful guidance for the integrity monitoring of civil structures, especially pavements.

  12. Functionality Enhancement of Industrialized Optical Fiber Sensors and System Developed for Full-Scale Pavement Monitoring

    Directory of Open Access Journals (Sweden)

    Huaping Wang

    2014-05-01

    Full Text Available Pavements always play a predominant role in transportation. Health monitoring of pavements is becoming more and more significant, as frequently suffering from cracks, rutting, and slippage renders them prematurely out of service. Effective and reliable sensing elements are thus in high demand to make prognosis on the mechanical properties and occurrence of damage to pavements. Therefore, in this paper, various types of functionality enhancement of industrialized optical fiber sensors for pavement monitoring are developed, with the corresponding operational principles clarified in theory and the performance double checked by basic experiments. Furthermore, a self-healing optical fiber sensing network system is adopted to accomplish full-scale monitoring of pavements. The application of optical fiber sensors assembly and self-healing network system in pavement has been carried out to validate the feasibility. It has been proved that the research in this article provides a valuable method and meaningful guidance for the integrity monitoring of civil structures, especially pavements.

  13. Combined CT and fluoroscopic guidance of balloon kyphoplasty versus fluoroscopy-only procedures

    Energy Technology Data Exchange (ETDEWEB)

    Amoretti, Nicolas; Marcy, Pierre-Yves; Lesbats-Jacquot, Virginie; Fonquerne, Marie-Eve; Hericord, Olivier; Maratos, Yvonne [Centre Hospitalier Universitaire de Nice, Service de Radiologie, Nice (France); Hovorka, Istvan [Centre Hospitalier Universitaire de Nice, Spine Surgery Department, Nice (France); Roux, Christian; Euller-Ziegler, Liana [Centre Hospitalier Universitaire de Nice, Rheumatology Department, Nice (France)

    2009-07-15

    To evaluate the performance of combined (computed tomography (CT) and fluoroscopic) guidance of balloon kyphoplasty in comparison to fluoroscopic guidance alone. Forty-one kyphoplasties were performed between January 2005 and March 2006 according to two different protocols. Study group 1 consisted of 20 consecutive patients with 20 balloon kyphoplasty procedures under dual guidance (CT scan and fluoroscopy) for osteoporotic or traumatic vertebral fractures. Study group 2 consisted of 21 consecutive patients in whom kyphoplasty was performed with fluoroscopy alone. Visualization of the pedicles, the final of the balloon position, and cement distribution were evaluated(1 - poor, 2 - intermediate, 3 - good). Combined use of CT and fluoroscopy (group 1) was superior in identifying the pedicles (100% versus 66.7%, p = 0.009) and balloon placement (100% versus 71.4%, p = 0.02) but not in monitoring of cement distribution within the vertebral body (100% versus 90.5%, p = 0.49). The difference between the two groups was more pronounced in the thoracic spine than in the lumbar spine. CT/fluoroscopic guidance of kyphoplasty combines safe CT-guided insertion of the osteointroducers and balloons as well as fluoroscopic real-time monitoring of polymethylmethacrylate injection. (orig.)

  14. Accounting for complementarity to maximize monitoring power for species management.

    Science.gov (United States)

    Tulloch, Ayesha I T; Chadès, Iadine; Possingham, Hugh P

    2013-10-01

    To choose among conservation actions that may benefit many species, managers need to monitor the consequences of those actions. Decisions about which species to monitor from a suite of different species being managed are hindered by natural variability in populations and uncertainty in several factors: the ability of the monitoring to detect a change, the likelihood of the management action being successful for a species, and how representative species are of one another. However, the literature provides little guidance about how to account for these uncertainties when deciding which species to monitor to determine whether the management actions are delivering outcomes. We devised an approach that applies decision science and selects the best complementary suite of species to monitor to meet specific conservation objectives. We created an index for indicator selection that accounts for the likelihood of successfully detecting a real trend due to a management action and whether that signal provides information about other species. We illustrated the benefit of our approach by analyzing a monitoring program for invasive predator management aimed at recovering 14 native Australian mammals of conservation concern. Our method selected the species that provided more monitoring power at lower cost relative to the current strategy and traditional approaches that consider only a subset of the important considerations. Our benefit function accounted for natural variability in species growth rates, uncertainty in the responses of species to the prescribed action, and how well species represent others. Monitoring programs that ignore uncertainty, likelihood of detecting change, and complementarity between species will be more costly and less efficient and may waste funding that could otherwise be used for management. © 2013 Society for Conservation Biology.

  15. Dry Cask Storage Inspection and Monitoring. Interim Report.

    Energy Technology Data Exchange (ETDEWEB)

    Bakhtiari, Susan [Argonne National Lab. (ANL), Argonne, IL (United States); Elmer, Thomas W. [Argonne National Lab. (ANL), Argonne, IL (United States); Koehl, Eugene R. [Argonne National Lab. (ANL), Argonne, IL (United States); Wang, Ke [Argonne National Lab. (ANL), Argonne, IL (United States); Raptis, Apostolos C. [Argonne National Lab. (ANL), Argonne, IL (United States); Kunerth, Dennis C. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Birk, Sandra M. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-03-04

    Recently, the U.S. Nuclear Regulatory Commission (NRC) issued the guidance on the aging management of dry storage facilities that indicates the necessity to monitor the conditions of dry cask storage systems (DCSSs) over extended periods of time.1 Part of the justification of the aging management plans is the requirement for inspection and monitoring to verify whether continued monitoring, inspection or mitigation are necessary. To meet this challenge Argonne National Laboratory (ANL) in collaboration with Idaho National Laboratory (INL) is conducting scoping studies on current and emerging nondestructive evaluation/examination (NDE) and online monitoring (OLM) technologies for DCSS integrity assessments. The scope of work plan includes identification and verification of technologies for long-term online monitoring of DCSSs’ crucial physical parameters such as temperature, pressure, leakage and structural integrity in general. Modifications have been made to the current technologies to accommodate field inspections and monitoring. A summary of the scoping studies and experimental efforts conducted to date as well as plans for future activities is provided below.

  16. Powered Descent Guidance with General Thrust-Pointing Constraints

    Science.gov (United States)

    Carson, John M., III; Acikmese, Behcet; Blackmore, Lars

    2013-01-01

    The Powered Descent Guidance (PDG) algorithm and software for generating Mars pinpoint or precision landing guidance profiles has been enhanced to incorporate thrust-pointing constraints. Pointing constraints would typically be needed for onboard sensor and navigation systems that have specific field-of-view requirements to generate valid ground proximity and terrain-relative state measurements. The original PDG algorithm was designed to enforce both control and state constraints, including maximum and minimum thrust bounds, avoidance of the ground or descent within a glide slope cone, and maximum speed limits. The thrust-bound and thrust-pointing constraints within PDG are non-convex, which in general requires nonlinear optimization methods to generate solutions. The short duration of Mars powered descent requires guaranteed PDG convergence to a solution within a finite time; however, nonlinear optimization methods have no guarantees of convergence to the global optimal or convergence within finite computation time. A lossless convexification developed for the original PDG algorithm relaxed the non-convex thrust bound constraints. This relaxation was theoretically proven to provide valid and optimal solutions for the original, non-convex problem within a convex framework. As with the thrust bound constraint, a relaxation of the thrust-pointing constraint also provides a lossless convexification that ensures the enhanced relaxed PDG algorithm remains convex and retains validity for the original nonconvex problem. The enhanced PDG algorithm provides guidance profiles for pinpoint and precision landing that minimize fuel usage, minimize landing error to the target, and ensure satisfaction of all position and control constraints, including thrust bounds and now thrust-pointing constraints.

  17. Guidance system for laser targets

    Science.gov (United States)

    Porter, Gary D.; Bogdanoff, Anatoly

    1978-01-01

    A system for guiding charged laser targets to a predetermined focal spot of a laser along generally arbitrary, and especially horizontal, directions which comprises a series of electrostatic sensors which provide inputs to a computer for real time calculation of position, velocity, and direction of the target along an initial injection trajectory, and a set of electrostatic deflection means, energized according to a calculated output of said computer, to change the target trajectory to intercept the focal spot of the laser which is triggered so as to illuminate the target of the focal spot.

  18. 75 FR 76011 - Annual Guidance Agenda

    Science.gov (United States)

    2010-12-07

    ..., Early Clinical Trials With Live Outreach and Development, Biotherapeutic Products: Chemistry, Center for... topic categories. II. Center for Biologics Evaluation and Research (CBER) ] Title/topic of guidance... Intended for Evaluation and Research (HFM- Transfusion or for Further Manufacture 40), Food and Drug...

  19. Cannabinoid receptor CB2 modulates axon guidance

    DEFF Research Database (Denmark)

    Duff, Gabriel; Argaw, Anteneh; Cecyre, Bruno

    2013-01-01

    Navigation of retinal projections towards their targets is regulated by guidance molecules and growth cone transduction mechanisms. Here, we present in vitro and in vivo evidences that the cannabinoid receptor 2 (CB2R) is expressed along the retino-thalamic pathway and exerts a modulatory action ...

  20. Guidance on Port Biological Baseline Surveys (PBBS)

    Digital Repository Service at National Institute of Oceanography (India)

    Awad, A.; Haag, F.; Anil, A.C.; Abdulla, A.

    This publication has been prepared by GBP, IOI, CSIR-NIO and IUCN in order to serve as guidance to those who are planning to carry out a port biological baseline survey, in particular in the context of Ballast Water Management. It has been drafted...

  1. Nigerian Journal of Guidance and Counselling

    African Journals Online (AJOL)

    The Nigerian Journal of Guidance and Counselling (TNJGC) (ISSN 0794-0831) is published annually by the Department of Counsellor Education, University of Ilorin, Ilorin, Nigeria. The journal publishes well researched and well articulated papers/articles on all issues relating to counselling and applied psychology which ...

  2. Children and Crises: A Developmental Guidance Approach.

    Science.gov (United States)

    Allan, John; Anderson, Eileen

    This paper describes a developmental guidance program on the topic of children and crises from kindergarten through grade eight. Many crises that children may deal with are discussed, including accidents, illness, death of a loved one, family problems, and moving. A crisis education response program developed and initiated to facilitate an…

  3. Guidance for performing site inspections under CERCLA

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    This guidance presents EPA`s site inspection (SI) strategy. The strategy discusses procedural guidelines to investigate potential Superfund (CERCLA) sites for evaluation pursuant to the Hazard Ranking System (HRS), revised in accordance with the Superfund Amendments and Reauthorization Act of 1986. The HRS is the primary means by which EPA evaluates sites for superfund`s National Priorities List (NPL).

  4. Teacher trainees' appraisal of guidance and counselling ...

    African Journals Online (AJOL)

    The study appraised the guidance and counselling services in Colleges of Education in Ghana. Four research questions were posed to direct the study. The evaluation research design was used whilst a multi – stage sampling procedure was employed to select a sample of 185 students. A 40–item questionnaire with ...

  5. Bridge over troubled water: Guidance crosses | Amundson ...

    African Journals Online (AJOL)

    This article is based on a keynote presentation at an international conference where the focus was cross-over career guidance. Simon and Garfunkel's popular song, "Bridge over troubled water", was used as a metaphor for exploring the cross-over theme. Some of the concepts under consideration included the working ...

  6. 36 CFR 1290.7 - Additional guidance.

    Science.gov (United States)

    2010-07-01

    ... Section 1290.7 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION JFK... ASSASSINATION RECORDS COLLECTION ACT OF 1992 (JFK ACT) § 1290.7 Additional guidance. (a) A government agency, office, or entity includes, for purposes of interpreting and implementing the JFK Act, all current, past...

  7. Assessment of a personalized and distributed patient guidance system.

    Science.gov (United States)

    Peleg, Mor; Shahar, Yuval; Quaglini, Silvana; Broens, Tom; Budasu, Roxana; Fung, Nick; Fux, Adi; García-Sáez, Gema; Goldstein, Ayelet; González-Ferrer, Arturo; Hermens, Hermie; Hernando, M Elena; Jones, Val; Klebanov, Guy; Klimov, Denis; Knoppel, Daniel; Larburu, Nekane; Marcos, Carlos; Martínez-Sarriegui, Iñaki; Napolitano, Carlo; Pallàs, Àngels; Palomares, Angel; Parimbelli, Enea; Pons, Belén; Rigla, Mercedes; Sacchi, Lucia; Shalom, Erez; Soffer, Pnina; van Schooten, Boris

    2017-05-01

    ' compliance to CIG recommendations and their satisfaction and quality of life. Our evaluation has demonstrated the system's capability for supporting distributed decision-making and its use by patients and clinicians. The results show that compliance of GDM patients to the most important monitoring targets - blood glucose levels (performance of four measurements a day: 0.87±0.11; measurement according to the recommended frequency of every day or twice a week: 0.99±0.03), ketonuria (0.98±0.03), and blood pressure (0.82±0.24) - was high in most GDM patients, while compliance of AF patients to the most important targets was quite high, considering the required ECG measurements (0.65±0.28) and blood-pressure measurements (0.75±1.33). This outcome was viewed by the clinicians as a major potential benefit of the system, and the patients have demonstrated that they are capable of self-monitoring - something that they had not experienced before. In addition, the system caused the clinicians managing the AF patients to change their diagnosis and subsequent treatment for two of the ten AF patients, and caused the clinicians managing the GDM patients to start insulin therapy earlier in two of the 19 patients, based on system's recommendations. Based on the end-of-study questionnaires, the sense of safety that the system has provided to the patients was its greatest asset. Analysis of the patients' quality of life (QoL) questionnaires for the AF patients was inconclusive, because while most patients reported an improvement in their quality of life in the EuroQoL questionnaire, most AF patients reported a deterioration in the AFEQT questionnaire. Feasibility and some of the potential benefits of an evidence-based distributed patient-guidance system were demonstrated in both clinical domains. The potential application of MobiGuide to other medical domains is supported by its standards-based patient health record with multiple electronic medical record linking capabilities, generic

  8. Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants with Possible Congenital Zika Virus Infection - United States, October 2017.

    Science.gov (United States)

    Adebanjo, Tolulope; Godfred-Cato, Shana; Viens, Laura; Fischer, Marc; Staples, J Erin; Kuhnert-Tallman, Wendi; Walke, Henry; Oduyebo, Titilope; Polen, Kara; Peacock, Georgina; Meaney-Delman, Dana; Honein, Margaret A; Rasmussen, Sonja A; Moore, Cynthia A

    2017-10-20

    CDC has updated its interim guidance for U.S. health care providers caring for infants with possible congenital Zika virus infection (1) in response to recently published updated guidance for health care providers caring for pregnant women with possible Zika virus exposure (2), unknown sensitivity and specificity of currently available diagnostic tests for congenital Zika virus infection, and recognition of additional clinical findings associated with congenital Zika virus infection. All infants born to mothers with possible Zika virus exposure* during pregnancy should receive a standard evaluation at birth and at each subsequent well-child visit including a comprehensive physical examination, age-appropriate vision screening and developmental monitoring and screening using validated tools (3-5), and newborn hearing screen at birth, preferably using auditory brainstem response (ABR) methodology (6). Specific guidance for laboratory testing and clinical evaluation are provided for three clinical scenarios in the setting of possible maternal Zika virus exposure: 1) infants with clinical findings consistent with congenital Zika syndrome regardless of maternal testing results, 2) infants without clinical findings consistent with congenital Zika syndrome who were born to mothers with laboratory evidence of possible Zika virus infection, † and 3) infants without clinical findings consistent with congenital Zika syndrome who were born to mothers without laboratory evidence of possible Zika virus infection. Infants in the first two scenarios should receive further testing and evaluation for Zika virus, whereas for the third group, further testing and clinical evaluation for Zika virus are not recommended. Health care providers should remain alert for abnormal findings (e.g., postnatal-onset microcephaly and eye abnormalities without microcephaly) in infants with possible congenital Zika virus exposure without apparent abnormalities at birth.

  9. Design and optimization of navigation and guidance techniques for Mars pinpoint landing: Review and prospect

    Science.gov (United States)

    Yu, Zhengshi; Cui, Pingyuan; Crassidis, John L.

    2017-10-01

    Future Mars landing missions will require the capability of precise landing at certain sites for specific scientific interests to gather more valuable scientific information. Autonomous navigation and guidance in the Mars approach, entry, descent, and landing (AEDL) phase plays an important role in fulfilling a pinpoint landing mission. This paper systematically summarizes the latest developments and current status of autonomous navigation and guidance designs for Mars landing missions. Firstly, the AEDL phase for Mars landing is analyzed, and several landmark Mars landing missions are reviewed. Based on the precision requirement, the technology challenges of autonomous navigation and guidance for Mars pinpoint landing are discussed. Then, recent developments of autonomous navigation design, which contain the navigation scheme and state estimation methods are summarized. Furthermore, the cutting-edge concept of navigation scheme optimization is also introduced, which may provide new ideas to the mission design. Next, the state-of-art guidance technologies of entry and powered descent phases are analyzed. The corresponding reachable and controllable set analysis, trajectory optimization, and advanced guidance methods are also revealed. Finally, aiming to support future Mars pinpoint landing missions, a comprehensive prospective for the development of autonomous navigation and guidance is presented.

  10. The faces of Moebius syndrome: recognition and anticipatory guidance.

    Science.gov (United States)

    Broussard, Anne Bienvenu; Borazjani, June G

    2008-01-01

    Moebius syndrome is a rare congenital disorder characterized mainly by the inability to move the eyes laterally or produce facial expressions such as smiling. Moebius syndrome creates physical problems for the affected individual that may, in some cases, lead to emotional or social adjustment issues, yet the syndrome is relatively unknown among healthcare professionals. Because early recognition of Moebius syndrome can lead to early diagnosis and treatment, education of nurses in perinatal, pediatric, midwifery, and neonatal specialties is crucial. Through early recognition, maternal-child nurses can offer anticipatory guidance and provide or recommend resources to parents of children with this neurological condition.

  11. Vision-based guidance for an automated roving vehicle

    Science.gov (United States)

    Griffin, M. D.; Cunningham, R. T.; Eskenazi, R.

    1978-01-01

    A controller designed to guide an automated vehicle to a specified target without external intervention is described. The intended application is to the requirements of planetary exploration, where substantial autonomy is required because of the prohibitive time lags associated with closed-loop ground control. The guidance algorithm consists of a set of piecewise-linear control laws for velocity and steering commands, and is executable in real time with fixed-point arithmetic. The use of a previously-reported object tracking algorithm for the vision system to provide position feedback data is described. Test results of the control system on a breadboard rover at the Jet Propulsion Laboratory are included.

  12. Studying Wind Energy/Bird Interactions: A Guidance Document

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, R. [California Energy Commission (US); Morrison, M. [California State Univ., Sacramento, CA (US); Sinclair, K. [Dept. of Energy/National Renewable Energy Lab. (US); Strickland, D. [WEST, Inc. (US)

    1999-12-01

    This guidance document is a product of the Avian Subcommittee of the National Wind Coordinating Committee (NWCC). The NWCC was formed to better understand and promote responsible, credible, and comparable avian/wind energy interaction studies. Bird mortality is a concern and wind power is a potential clean and green source of electricity, making study of wind energy/bird interactions essential. This document provides an overview for regulators and stakeholders concerned with wind energy/bird interactions, as well as a more technical discussion of the basic concepts and tools for studying such interactions.

  13. Guidance on the management of pain in older people.

    Science.gov (United States)

    Abdulla, Aza; Adams, Nicola; Bone, Margaret; Elliott, Alison M; Gaffin, Jean; Jones, Derek; Knaggs, Roger; Martin, Denis; Sampson, Liz; Schofield, Pat

    2013-03-01

    This guidance document reviews the epidemiology and management of pain in older people via a literature review of published research. The aim of this document is to inform health professionals in any care setting who work with older adults on best practice for the management of pain and to identify where there are gaps in the evidence that require further research. The assessment of pain in older people has not been covered within this guidance and can be found in a separate document (http://www.britishpainsociety.org/pub_professional.htm#assessmentpop). Substantial differences in the population, methods and definitions used in published research makes it difficult to compare across studies and impossible to determine the definitive prevalence of pain in older people. There are inconsistencies within the literature as to whether or not pain increases or decreases in this age group, and whether this is influenced by gender. There is, however, some evidence that the prevalence of pain is higher within residential care settings. The three most common sites of pain in older people are the back; leg/knee or hip and 'other' joints. In common with the working-age population, the attitudes and beliefs of older people influence all aspects of their pain experience. Stoicism is particularly evident within this cohort of people. Evidence from the literature search suggests that paracetamol should be considered as first-line treatment for the management of both acute and persistent pain, particularly that which is of musculoskeletal origin, due to its demonstrated efficacy and good safety profile. There are few absolute contraindications and relative cautions to prescribing paracetamol. It is, however, important that the maximum daily dose (4 g/24 h) is not exceeded. Non-selective non-steroidal anti-inflammatory drugs (NSAIDs) should be used with caution in older people after other safer treatments have not provided sufficient pain relief. The lowest dose should be provided

  14. Federal Radiological Monitoring and Assessment Center Monitoring Manual Volume 2, Radiation Monitoring and Sampling

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Aerial Measurement Systems

    2012-07-31

    The FRMAC Monitoring and Sampling Manual, Volume 2 provides standard operating procedures (SOPs) for field radiation monitoring and sample collection activities that are performed by the Monitoring group during a FRMAC response to a radiological emergency.

  15. Chemical Agent Monitor (CAM) follow-on operational test and evaluation simulant test strategy. Final report, May 1988-April 1989

    Energy Technology Data Exchange (ETDEWEB)

    Seitzinger, A.T.; Grasso, P.S.; Guelta, M.A.

    1990-06-01

    This report was intended to provide technical guidance to the U.S. Army Armor and Engineering (A E) Board in the area of simulant use for the Chemical Agent Monitor (CAM) Follow-on Operational Test and Evaluation (FOT E). The Operational Science Branch (Op Sci Br) was requested to support the A E Board in their effort to design an FOT E for the CAM using methyl salicylate (MS) as the H mode (mustard agent) simulant. Personnel from Op Sci Br were asked to design contamination technology and monitoring methods to test the machine/man interface and use doctrine, and analyze how well data is collected and evaluated.

  16. Structural Safety Monitoring of High Arch Dam Using Improved ABC-BP Model

    Directory of Open Access Journals (Sweden)

    Yantao Zhu

    2016-01-01

    Full Text Available The establishment of a structural safety monitoring model of a dam is necessary for the evaluation of the dam’s deformation status. The structural safety monitoring method based on the monitoring data is widely used in traditional research. On the basis of the analysis of the high arch dam’s deformation principles, this study proposes a structural safety monitoring method derived from the dam deformation monitoring data. The method first analyzes and establishes the spatial and temporal distribution of high arch dam’s safety monitoring, overcoming the standard artificial bee colony (ABC algorithm’s shortcoming of easily falling into the local optimum by adopting the adaptive proportion and average Euclidean distance afterwards. The improved ABC algorithm is used to optimize the backpropagation (BP neural network’s initial weight and threshold. The application example proves that ABC-BP model’s improvement method is important for the establishment of a high arch deformation safety monitoring model and can effectively improve the model’s fitting and forecasting ability. This method provides a reference for the establishment of a structural safety monitoring model of dam and provides guidance for the establishment of a forecasting model in other fields.

  17. State of Data Guidance in Journal Policies: A Case Study in Oncology

    Directory of Open Access Journals (Sweden)

    Deborah H. Charbonneau

    2015-06-01

    Full Text Available This article reports the results of a study examining the state of data guidance provided to authors by 50 oncology journals. The purpose of the study was the identification of data practices addressed in the journals’ policies. While a number of studies have examined data sharing practices among researchers, little is known about how journals address data sharing. Thus, what was discovered through this study has practical implications for journal publishers, editors, and researchers. The findings indicate that journal publishers should provide more meaningful and comprehensive data guidance to prospective authors. More specifically, journal policies requiring data sharing, should direct researchers to relevant data repositories, and offer better metadata consultation to strengthen existing journal policies. By providing adequate guidance for authors, and helping investigators to meet data sharing mandates, scholarly journal publishers can play a vital role in advancing access to research data.

  18. Essentials for starting a pediatric clinical study (4): Clinical pediatric safety planning based on preclinical toxicity studies and pediatric pharmacovigilance guidance.

    Science.gov (United States)

    Sheth, Neha

    2009-01-01

    Juvenile toxicology studies in animals provide useful information to guide monitoring of potential adverse effects in children especially on growth and development. In order to continue to gain knowledge and build upon these preclinical studies, recent experience has suggested that additional approaches for monitoring of safety concerns in the pediatric population may be required. Recently, pediatric guidance has become available from the health authorities which provide pharmacovigilance concepts as they specifically relate to drugs being developed for pediatric indications. Clinical trials are typically not robust enough to detect rare or delayed safety effects as the pediatric trials are relatively short-term. Furthermore, such long term or rare effects may not be detected via standard voluntary postmarketing surveillance. Safety monitoring of children with Juvenile Inflammatory Arthritis (JIA) taking nonsteroid anti-inflammatory drug (NSAID)s will be used as an example to describe a post-marketing risk management and pharmacovigilance program that serves to better evaluate safety data from various sources. The intent of this program is to identify adverse events (AE), including events with longer latency, which may be associated with NSAID use in a pediatric population. In this presentation, the 4 major components of the program are to be addressed. Such a program may serve as a model to proactively generate and monitor safety data in order to identify AEs that may be associated with new therapeutics for a pediatric population.

  19. Orion Entry Display Feeder and Interactions with the Entry Monitor System

    Science.gov (United States)

    Baird, Darren; Bernatovich, Mike; Gillespie, Ellen; Kadwa, Binaifer; Matthews, Dave; Penny, Wes; Zak, Tim; Grant, Mike; Bihari, Brian

    2010-01-01

    The Orion spacecraft is designed to return astronauts to a landing within 10 km of the intended landing target from low Earth orbit, lunar direct-entry, and lunar skip-entry trajectories. Al pile the landing is nominally controlled autonomously, the crew can fly precision entries manually in the event of an anomaly. The onboard entry displays will be used by the crew to monitor and manually fly the entry, descent, and landing, while the Entry Monitor System (EMS) will be used to monitor the health and status of the onboard guidance and the trajectory. The entry displays are driven by the entry display feeder, part of the Entry Monitor System (EMS). The entry re-targeting module, also part of the EMS, provides all the data required to generate the capability footprint of the vehicle at any point in the trajectory, which is shown on the Primary Flight Display (PFD). It also provides caution and warning data and recommends the safest possible re-designated landing site when the nominal landing site is no longer within the capability of the vehicle. The PFD and the EMS allow the crew to manually fly an entry trajectory profile from entry interface until parachute deploy having the flexibility to manually steer the vehicle to a selected landing site that best satisfies the priorities of the crew. The entry display feeder provides data from the ENIS and other components of the GNC flight software to the displays at the proper rate and in the proper units. It also performs calculations that are specific to the entry displays and which are not made in any other component of the flight software. In some instances, it performs calculations identical to those performed by the onboard primary guidance algorithm to protect against a guidance system failure. These functions and the interactions between the entry display feeder and the other components of the EMS are described.

  20. Regulatory Guidance for Permeable Reactive Barriers Designed to Remediate Inorganic and Radionuclide Contamination

    Science.gov (United States)

    1999-09-01

    aquifer boundaries, • Discussion of major withdrawals or recharge to the aquifer, • Leakage from overlying bodies of water, wetlands or underlying...within a wetlands area. UIC requirements will typically not be applicable for the installation of a PRB. However, monitoring for leachability of the...www.epa.gov/swerust1/directiv/9200417z.htm USEPA, September 1994. Guidance for the DQO Process. (USEPA QA/G4) US Geological Survey for the Federal

  1. nowCOAST's Map Service for NOAA NOS Delaware Bay Operational Forecast System (DBOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of surface water temperature, salinity, water...

  2. nowCOAST's Map Service for NOAA NOS Northwest Gulf of Mexico Operational Forecast System (NWGOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  3. nowCOAST's Map Service for NOAA NOS San Francisco Bay Operational Forecast System (SFBOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  4. nowCOAST's Map Service for NOAA NOS Delaware Bay Operational Forecast System (DBOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of surface water temperature, salinity, and water...

  5. nowCOAST's Map Service for NOAA NOS Tampa Bay Operational Forecast System (TBOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  6. nowCOAST's Map Service for NOAA NOS Chesapeake Bay Operational Forecast System (CBOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  7. nowCOAST's Map Service for NOAA NOS Columbia River Estuary Operational Forecast System (CREOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offets map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents, and...

  8. nowCOAST's Map Service for NOAA NOS Northern Gulf of Mexico Operational Forecast System (NGOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  9. nowCOAST's Map Service for NOAA NOS Northeast Gulf of Mexico Operational Forecast System (NEGOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  10. nowCOAST's Map Service for NOAA NOS Northern Gulf of Mexico Operational Forecast System (NGOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  11. nowCOAST's Map Service for NOAA NOS St. Johns River Operational Forecast System (SJROFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of surface water temperature, salinity, and water...

  12. nowCOAST's Map Service for NOAA NOS Columbia River Estuary Operational Forecast System (CREOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  13. nowCOAST's Map Service for NOAA NOS St. Johns River Operational Forecast System (SJROFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of surface water temperature, salinity, and water...

  14. nowCOAST's Map Service for NOAA NOS Tampa Bay Operational Forecast System (TBOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  15. nowCOAST's Map Service for Geo-Referenced Hyperlinks to Forecast Guidance or Predictions at Point Locations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST geolinks map service provides maps depicting the locations where NOAA point forecast guidance or predictions are available along with...

  16. NAFTA Guidance Document on Data Requirements for Tolerances on Imported Commodities in the United States and Canada

    Science.gov (United States)

    The purpose of this document is to provide detailed guidance on data requirements that meet the North American Free Trade Agreement standards for the establishment of pesticide import tolerances or maximum residue levels in Canada and the United States.

  17. 77 FR 37059 - Draft Guidance for Industry on Active Controls in Studies To Demonstrate Effectiveness of a New...

    Science.gov (United States)

    2012-06-20

    ... advantages and disadvantages of using a study with an active control. Examples are provided to illustrate... with access to the Internet may obtain the draft guidance at either http://www.fda.gov/AnimalVeterinary...

  18. nowCOAST's Map Service for NOAA NOS Lake Superior Operational Forecast System (LSOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  19. nowCOAST's Map Service for NOAA NOS Lake Superior Operational Forecast System (LSOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  20. nowCOAST's Map Service for NOAA NOS San Francisco Bay Operational Forecast System (SFBOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  1. nowCOAST's Map Service for NOAA NOS Extratropical Surge and Tide Operational Forecast System (ESTOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of combined (tides + wind driven) water level and...

  2. nowCOAST's Map Service for NOAA NOS Lake Michigan Operational Forecast System (LMOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map services provides map of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  3. nowCOAST's Map Service for NOAA NOS Lake Ontario Operational Forecast System (LOOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  4. nowCOAST's Map Service for NOAA NOS Lake Michigan Operational Forecast System (LMOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map services provides map of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  5. nowCOAST's Map Service for NOAA NOS Chesapeake Bay Operational Forecast System (CBOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of water temperature, salinity, water currents,...

  6. nowCOAST's Map Service for NOAA NOS Lake Huron Operational Forecast System (LHOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  7. nowCOAST's Map Service for NOAA NOS Lake Ontario Operational Forecast System (LOOFS) Forecast Guidance (Time Offsets)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-offsets map service provides maps of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  8. nowCOAST's Map Service for NOAA NOS Lake Huron Operational Forecast System (LHOFS) Forecast Guidance (Time Enabled)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Map Information: This nowCOAST time-enabled map service provides maps of the latest nowcasts and forecast guidance of water temperature, water currents, and water...

  9. NSRD-10: Leak Path Factor Guidance Using MELCOR

    Energy Technology Data Exchange (ETDEWEB)

    Louie, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Humphries, Larry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    Estimates of the source term from a U.S. Department of Energy (DOE) nuclear facility requires that the analysts know how to apply the simulation tools used, such as the MELCOR code, particularly for a complicated facility that may include an air ventilation system and other active systems that can influence the environmental pathway of the materials released. DOE has designated MELCOR 1.8.5, an unsupported version, as a DOE ToolBox code in its Central Registry, which includes a leak-path-factor guidance report written in 2004 that did not include experimental validation data. To continue to use this MELCOR version requires additional verification and validations, which may not be feasible from a project cost standpoint. Instead, the recent MELCOR should be used. Without any developer support and lack of experimental data validation, it is difficult to convince regulators that the calculated source term from the DOE facility is accurate and defensible. This research replaces the obsolete version in the 2004 DOE leak path factor guidance report by using MELCOR 2.1 (the latest version of MELCOR with continuing modeling development and user support) and by including applicable experimental data from the reactor safety arena and from applicable experimental data used in the DOE-HDBK-3010. This research provides best practice values used in MELCOR 2.1 specifically for the leak path determination. With these enhancements, the revised leak-path-guidance report should provide confidence to the DOE safety analyst who would be using MELCOR as a source-term determination tool for mitigated accident evaluations.

  10. Blending Research and Practice: A 10-Year Evaluation of a Community-Based Child Guidance Clinic.

    Science.gov (United States)

    Mueller, Daniel P.; Hosley, Cheryl A.; Heiserman, Mary S.

    This document discusses a project designed to assess trends in service data and the effectiveness of the services provided over a 10-year period. It begins by describing the services provided by the Wilder Foundation Child Guidance Clinic, an outpatient mental health center serving children and families in the Saint Paul, Minnesota area. A number…

  11. 75 FR 875 - Guidance for Industry on New Contrast Imaging Indication Considerations for Devices and Approved...

    Science.gov (United States)

    2010-01-06

    .../biological products that provide image contrast enhancement. The final guidance announced in this document... specific medical imaging indications (e.g., myocardial perfusion or breast cancer imaging) and offered... developers of medical imaging devices and imaging drug/ biological products that provide image contrast...

  12. HANDBOOK: GUIDANCE ON SETTING PERMIT CONDITIONS AND REPORTING TRIAL BURN RESULTS

    Science.gov (United States)

    This Handbook provides guidance for establishing operational conditions for incinerators. he document provides a means for state and local agencies to achieve a level of consistency in setting permit conditions that will result in establishment of more uniform permit conditions n...

  13. Best Practices for Dual-Energy X-ray Absorptiometry Measurement and Reporting: International Society for Clinical Densitometry Guidance.

    Science.gov (United States)

    Lewiecki, E Michael; Binkley, Neil; Morgan, Sarah L; Shuhart, Christopher R; Camargos, Bruno Muzzi; Carey, John J; Gordon, Catherine M; Jankowski, Lawrence G; Lee, Joon-Kiong; Leslie, William D

    2016-01-01

    Dual-energy X-ray absorptiometry (DXA) is a technology that is widely used to diagnose osteoporosis, assess fracture risk, and monitor changes in bone mineral density (BMD). The clinical utility of DXA is highly dependent on the quality of the scan acquisition, analysis, and interpretation. Clinicians are best equipped to manage patients when BMD measurements are correct and interpretation follows well-established standards. Poor-quality acquisition, analysis, or interpretation of DXA data may mislead referring clinicians, resulting in unnecessary diagnostic evaluations, failure to evaluate when needed, inappropriate treatment, or failure to provide medical treatment, with potentially ineffective, harmful, or costly consequences. Misallocation of limited healthcare resources and poor treatment decisions can be minimized, and patient care optimized, through meticulous attention to DXA instrument calibration, data acquisition and analysis, interpretation, and reporting. This document from the International Society for Clinical Densitometry describes quality standards for BMD testing at DXA facilities worldwide to provide guidance for DXA supervisors, technologists, interpreters, and clinicians. High-quality DXA testing is necessary for correct diagnostic classification and optimal fracture risk assessment, and is essential for BMD monitoring. Copyright © 2016 International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

  14. CDC Guidance for State and Local Public Health Officials and School Administrators for School (K-12) Responses to Influenza during the 2009-2010 School Year

    Science.gov (United States)

    Centers for Disease Control and Prevention, 2009

    2009-01-01

    This document provides guidance to help decrease the spread of flu among students and school staff during the 2009-2010 school year. This document expands upon earlier school guidance documents by providing a menu of tools that school and health officials can choose from based on conditions in their area. It recommends actions to take this school…

  15. 75 FR 48973 - Draft Guidance for Industry: Prevention of Salmonella

    Science.gov (United States)

    2010-08-12

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry: Prevention of Salmonella... availability of a draft guidance entitled ``Prevention of Salmonella Enteritidis in Shell Eggs During... ``Prevention of Salmonella Enteritidis in Shell Eggs During Production, Storage, and Transportation'' (the...

  16. Flu Vaccine Guidance for Patients with Immune Deficiency

    Science.gov (United States)

    ... Guidance for Patients with Immune Deficiency Share | Flu Vaccine Guidance for Patients with Immune Deficiency This article ... should patients with immune deficiency be given the vaccine? Immune deficient patients have a decreased resistance to ...

  17. A Businessman Looks at Guidance in the Schools

    Science.gov (United States)

    King, J. E.

    1974-01-01

    Suggests that businessmen generally agree that vocational guidance is poorly done in the schools. Proposes that a retired businessman would be a valuable resource for the conventional guidance officer. (Author/HMV)

  18. Assay Characterization Guidance Documents | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    CPTAC characterized assays are defined as those that meet the criteria described in the Assay Characterization Guidance Document. This guidance document aligns with recommendations by the research community as “fit-for-purpose” validation requirements of targeted proteomics assays.

  19. Navigating from the heights of technical rigour to the swampy reality: Lessons from New Zealand in population health outcomes monitoring

    Directory of Open Access Journals (Sweden)

    John Wren

    2008-06-01

    Full Text Available

    Background: The objective of this paper is to describe and discuss two documents produced by the New Zealand Ministry of Health concerning the monitoring of outcomes of public health programs. The New Zealand Government is increasingly expecting planners and managers of publicly funded services to shift their focus from the delivery of ‘outputs’ towards achievement of ‘outcomes’. Intervention logic models and outcomes monitoring are promoted by central government agencies as suitable management methods for implementing the change. [1-3]

    Methods: To help managers design and implement comprehensive, effective and measurable population health programmes the Ministry of Health recently published two guidance documents. The first document provided guidance about how to plan programmes using a generic logic model approach.[4] The second set out in detail a process on how to monitor population health programmes.[5] The intent of the documents was to help managers navigate between the heights of technical rigour and the swamps of reality in the delivery of population health programmes.[6]

    Results: A number of issues and implications for how population health programmes are planned monitored and performance assessed have been identified by the guidance documents. Issues include the problem of small numbers, understanding the difference between outcomes monitoring and traditional forms of evaluation, and outcomes monitoring being seen as a tool for punitive performance management rather than ‘continuous programme improvement’. Implications include more time spent on the design of programmes. Planners will need to focus upon better sequencing of activities, setting more specific and time limited goals, and to be more informed about how to use research to inform the selection of interventions.

    Conclusions: The guidance documents promoted by

  20. Wind Turbine Providing Grid Support

    DEFF Research Database (Denmark)

    2011-01-01

    A variable speed wind turbine is arranged to provide additional electrical power to counteract non-periodic disturbances in an electrical grid. A controller monitors events indicating a need to increase the electrical output power from the wind turbine to the electrical grid. The controller...

  1. 78 FR 39736 - Draft Guidance for Industry: Considerations for the Design of Early-Phase Clinical Trials of...

    Science.gov (United States)

    2013-07-02

    ...&C Act), or to the therapeutic biological products for which the Center for Drug Evaluation and... selection, treatment plans, monitoring and follow-up. Finally, the draft guidance encourages prospective... for Biologics Evaluation and Research (CBER), Food and Drug Administration, 1401 Rockville Pike, suite...

  2. Practical guidance for defining a smart grid modernization strategy the case of distribution

    CERN Document Server

    Madrigal, Marcelino

    2015-01-01

    This document provides some practical guidance on how utilities can define their own smart grid vision, identify priorities, and structure investment plans. While most of these strategic aspects apply to any area of the electricity grid, the document focuses on the segment of distribution. The guidance includes key building blocks that are needed to modernize the distribution grid and provides examples of grid modernization projects. Potential benefits that can be achieved (in monetary terms) for a given investment range are also discussed.The concept of the smart grid is relevant to any grid

  3. A review of Grey and academic literature of evaluation guidance relevant to public health interventions.

    Science.gov (United States)

    Denford, Sarah; Abraham, Charles; Callaghan, Margaret; Aighton, Peter; De Vocht, Frank; Arris, Steven

    2017-09-12

    Public Health evaluation is essential to understanding what does and does not work, and robust demonstration of effectiveness may be crucial to securing future funding. Despite this, programs are often implemented with poor, incomplete or no evaluation. Public health practitioners are frequently required to provide evidence for the effectiveness of their services; thus, there is a growing need for evaluation guidance on how to evaluate public health programs. The aim of this study is to identify accessible high-quality, evaluation guidance, available to researchers and practitioners and to catalogue, summarise and categorise the content of a subset of accessible, quality guides to evaluation. We systematically reviewed grey and academic literature for documents providing support for evaluation of complex health interventions. Searches were conducted January to March 2015, and included academic databases, internet search engines, and consultations with academic and practicing public health experts. Data were extracted by two authors and sent to the authors of the guidance documents for comments. Our initial search identified 402 unique documents that were screened to identify those that were (1) developed by or for a national or international organization (2) freely available to all (3) published during or after 2000 (4) specific to public health. This yielded 98 documents from 43 organisations. Of these, 48 were reviewed in detail. This generated a detailed catalogue of quality evaluation guidance. The content included in documents covers 37 facets of evaluation. A wide range of guidance on evaluation of public health initiatives is available. Time and knowledge constraints may mean that busy practitioners find it challenging to access the most, up-to-date, relevant and useful guidance. This review presents links to and reviews of 48 quality guides to evaluation as well as categorising their content. This facilitates quick and each access to multiple selected

  4. Climate Change Effects and Impacts Assessment. A guidance manual for Local Government in New Zealand

    Energy Technology Data Exchange (ETDEWEB)

    Wratt, D.; Mullan, B.; Salinger, J. [National Institute of Water and Atmospheric Research NIWA, Newmarket, Auckland (New Zealand); Allan, S.; Morgan, T. [MWH New Zealand, Christchurch (New Zealand); Kenny, G. [Earthwise Consulting, Hastings (New Zealand)

    2004-05-15

    Climate change is a real and internationally recognised outcome of increased amounts of greenhouse gases in the atmosphere. It will have effects over the next decades that are predictable with some level of certainty, but which will vary from place to place throughout New Zealand. The climate will also change from year to year and decade to decade due to natural processes. For example, some parts of the country often have dry summers and autumns when an El Nino climate pattern is present. Both natural fluctuations and human-induced climate changes need to be considered when developing adaptation plans and policies, rather than just 'greenhouse warming' effects on their own. Councils already address extreme weather events and climate variations as they develop plans and provide services. Climate change effects need also to be considered as part of these regulatory, assessment and planning activities. It is not necessary to develop a set of procedures for dealing separately with effects and impacts of climate change - they can be built into existing practices. Over time, climate change responses will involve iterative planning processes, keeping up-to-date with new information, monitoring changes, and reviewing the effectiveness of responses. The response to climate change involves international, national, regional, district and community consideration and action. The Guidance Manual aims to assist local government in working with its communities and making appropriate decisions.

  5. Multi-Lab EV Smart Grid Integration Requirements Study. Providing Guidance on Technology Development and Demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Markel, T. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Meintz, A. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hardy, K. [Argonne National Lab. (ANL), Argonne, IL (United States); Chen, B. [Argonne National Lab. (ANL), Argonne, IL (United States); Bohn, T. [Argonne National Lab. (ANL), Argonne, IL (United States); Smart, J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Scoffield, D. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hovsapian, R. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Saxena, S. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); MacDonald, J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kiliccote, S. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kahl, K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Pratt, R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-05-28

    The report begins with a discussion of the current state of the energy and transportation systems, followed by a summary of some VGI scenarios and opportunities. The current efforts to create foundational interface standards are detailed, and the requirements for enabling PEVs as a grid resource are presented. Existing technology demonstrations that include vehicle to grid functions are summarized. The report also includes a data-based discussion on the magnitude and variability of PEVs as a grid resource, followed by an overview of existing simulation tools that vi This report is available at no cost from the National Renewable Energy Laboratory (NREL) at www.nrel.gov/publications. can be used to explore the expansion of VGI to larger grid functions that might offer system and customer value. The document concludes with a summary of the requirements and potential action items that would support greater adoption of VGI.

  6. Proposal for evaluating computer programming algorithms to provide instructional guidance and give advice.

    OpenAIRE

    Jurado Monroy, Francisco

    2012-01-01

    La competencia de la Programación de Ordenadores es fundamental para los estudiantes de las diferentes titulaciones de Informática, dado que el conocimiento que deben adquirir y las habilidades que desarrollarán son vitales para el resto de su formación académica y para su futuro profesional. Sin embargo, los estudiantes de estas titulaciones se enfrentan a diferentes obstáculos a la hora de adquirir el conocimiento y las habilidades requeridas. Así, dificultades cognitivas ...

  7. Commanders and Cyber Chat: Should More Guidance be Provided for Social Networking Sites

    Science.gov (United States)

    2011-04-01

    revealing on Facebook his heavy drinking and fascination with female breasts; a Catholic school teacher was fired after posting on Facebook that he was gay ...www.rollingstone.com/politics/news/another-runaway-general-army-deploys-psy-ops-on- u -s-senators- 20110223 24 Ibid. 25 McMichael, W. "DoD may curb...Media and the Air Force" p. 7. 43 Ibid, p. 2. 44 Porterfield, Amy. Social Media Use Among Teens, Boomers and Moms : New Studies Reveal Great Insight

  8. A Surgical Robot Teleoperation Framework for Providing Haptic Feedback Incorporating Virtual Envrioment-Based Guidance

    Directory of Open Access Journals (Sweden)

    Adnan Munawar

    2016-08-01

    Full Text Available In robot-assisted tele-operated laparoscopic surgeries, the patient side manipulators are controlled via the master manipulators that are controlled by the surgeon. The current generation of robots approved for laparoscopic surgery lack haptic feedback. In theory, haptic feedback would enhance the surgical procedures by enabling better coordination between the hand movements that are improved by the tactile sense of the operating environment. This research presents an overall control framework for a haptic feedback on existing robot platforms, and demonstrated on the daVinci Research Kit (dVRK system. The paper discusses the implementation of a flexible framework that incorporates a stiffness control with gravity compensation for the surgeons manipulator and a sensing and collision detection algorithm for calculating the interaction between the patients manipulators and the surgical area.

  9. A simulation study provided sample size guidance for differential item functioning (DIF) studies using short scales

    DEFF Research Database (Denmark)

    Scott, Neil W; Fayers, Peter M; Aaronson, Neil K

    2009-01-01

    Differential item functioning (DIF) analyses are increasingly used to evaluate health-related quality of life (HRQoL) instruments, which often include relatively short subscales. Computer simulations were used to explore how various factors including scale length affect analysis of DIF by ordinal...

  10. Providing Career Guidance to Adolescents through Digital Games: A Case Study

    Science.gov (United States)

    Dunwell, Ian; Lameras, Petros; de Freitas, Sara; Petridis, Panos; Hendrix, Maurice; Arnab, Sylvester; Star, Kam

    2014-01-01

    In an evolving global workplace, it is increasingly important for graduates and school-leavers to possess an understanding of the job market, their relevant skills, and career progression paths. However, both the marketplace and career paths are becoming increasingly dynamic, with employees more frequently moving between sectors and positions than…

  11. Achievement Coaches Provide Adult Students with the Guidance Needed for Success

    Science.gov (United States)

    Jeffries, Kim

    2010-01-01

    Central New Mexico Community College (CNM) began as a small trade school in 1965. It has now become the largest institution of higher education in New Mexico in terms of enrollment. While most educational institutions offer student support in the form of academic advisers and counselors, CNM is a trailblazer. Beyond academic advisers, it has a…

  12. 75 FR 62820 - Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA

    Science.gov (United States)

    2010-10-13

    ... consequence pathogens and toxins that have the potential to pose a severe threat to human, animal, or plant... described in public comments as ``genes that can be intentionally abused,'' ``risk- associated'' genes, or..., including pathogens that could threaten public health, agriculture, plants, animals, the environment, or...

  13. Assessing adaptation to the health risks of climate change: what guidance can existing frameworks provide?

    Science.gov (United States)

    Füssel, Hans-Martin

    2008-02-01

    Climate change adaptation assessments aim at assisting policy-makers in reducing the health risks associated with climate change and variability. This paper identifies key characteristics of the climate-health relationship and of the adaptation decision problem that require consideration in climate change adaptation assessments. It then analyzes whether these characteristics are appropriately considered in existing guidelines for climate impact and adaptation assessment and in pertinent conceptual models from environmental epidemiology. The review finds three assessment guidelines based on a generalized risk management framework to be most useful for guiding adaptation assessments of human health. Since none of them adequately addresses all key challenges of the adaptation decision problem, actual adaptation assessments need to combine elements from different guidelines. Established conceptual models from environmental epidemiology are found to be of limited relevance for assessing and planning adaptation to climate change since the prevailing toxicological model of environmental health is not applicable to many climate-sensitive health risks.

  14. Guidance for health and social care providers, principles of good practice in medication reconciliation

    LENUS (Irish Health Repository)

    Ward, Marie

    2017-07-17

    Healthcare organisations have a responsibility for ensuring that the governance of workplace settings creates a culture that supports good professional practice. Encouraging such a culture needs to start from an understanding of the factors that make it difficult for health professionals to raise issues of concern in relation to patient safety. The focus of this study is to determine whether a customised education intervention, developed as part of the study, with interns and senior house officers (SHOs) can imbue a culture of medical professionalism in relation to patient safety and support junior doctors to raise issues of concern, while shaping a culture of responsiveness and learning.

  15. Content Analysis of Reference Transactions Provides Guidance Regarding Staffing of Library Service Points

    Directory of Open Access Journals (Sweden)

    Annie M. Hughes

    2014-07-01

    Full Text Available A Review of: Bishop, B. W., & Bartlett, J. A. (2013. Where do we go from here? Informing academic library staffing through reference transaction analysis. College & Research Libraries, 74(5, 489-500. Objective – To identify the quantity of location-based and subject-based questions and determine the locations where those questions are asked in order to inform decision-making regarding optimal placing of staff. Design – Content analysis of location-based and subject-based reference transactions or transcripts collected using LibStats at 15 face-to-face (f2f service points and via virtual services. Setting – Virtual and f2f service points at University of Kentucky (UK campus libraries. Subjects – 1,852 location-based and subject-based reference transactions gathered via a systematic sample of every 70th transaction out of 129,572 transactions collected. Methods – Using LibStats, the researchers collected data on location-based and subject-based questions at all service points at UK Libraries between 2008 and 2011. The researchers eliminated transcripts that did not include complete data or questions with fields left blank. If all question fields were properly completed, identification and coding of location-based or subject-based questions took place.

  16. A simulation study provided sample size guidance for differential item functioning (DIF) studies using short scales

    NARCIS (Netherlands)

    Scott, Neil W.; Fayers, Peter M.; Aaronson, Neil K.; Bottomley, Andrew; de Graeff, Alexander; Groenvold, Mogens; Gundy, Chad; Koller, Michael; Petersen, Morten A.; Sprangers, Mirjam A. G.

    Objective: Differential item functioning (DIF) analyses are increasingly used to evaluate health-related quality of life (HRQoL) instruments, which often include relatively short subscales. Computer simulations were used to explore how various factors including scale length affect analysis of DIF by

  17. attitude of secondary school students towards guidance and ...

    African Journals Online (AJOL)

    Elizabeth Egbochuku

    counsellors should be posted to practice and create awareness of guidance and counselling services. Introduction. Guidance and counselling as the third force in education along with instruction, is an integral part of educational system. Guidance programmes for secondary school students are designed to address the.

  18. Guidance East and West: A Collection of Occasional Papers.

    Science.gov (United States)

    ERIC Clearinghouse on Counseling and Personnel Services, Ann Arbor, MI.

    This book contains a collection of 14 papers dealing with guidance and guidance programs in the Philippines, the Republic of China, Japan, and Thailand. An overview of the place of American counselors in international guidance and benefits to counselors and the counseling profession of world-wide contacts is reviewed in the initial paper. Issues…

  19. 32 CFR 2001.16 - Fundamental classification guidance review.

    Science.gov (United States)

    2010-07-01

    ... a minimum, the fundamental classification guidance review shall focus on: (1) Evaluation of content... 32 National Defense 6 2010-07-01 2010-07-01 false Fundamental classification guidance review. 2001... INFORMATION Classification § 2001.16 Fundamental classification guidance review. (a) Performance of...

  20. Gestures in Guidance and Counselling and Their Pedagogical ...

    African Journals Online (AJOL)

    The purpose of this paper was to x-ray the implications of gestures, their usage and relevance in guidance and counselling. The historical background of guidance and counselling was traced and concepts like guidance, counselling and gesture were clarified. Gestures as non-verbal cues in counselling do not stand on its ...

  1. 21 CFR 7.59 - General industry guidance.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false General industry guidance. 7.59 Section 7.59 Food... POLICY Recalls (Including Product Corrections)-Guidance on Policy, Procedures, and Industry Responsibilities § 7.59 General industry guidance. A recall can be disruptive of a firm's operation and business...

  2. Design and implementation of artistic gymnastics training guidance system

    Science.gov (United States)

    Cai, Limin; Luo, Lin

    2017-04-01

    Artistic gymnastics (AG) has developed into a favorite sports activity among many university students; recent years saw not only the increase of AG learners, but also the emergence of more and more problems in the training. Based on surveys in different forms, students' physical quality and their performance in the AG training were analyzed and summarized; and with the aid of the computer technology, Artistic Gymnastics Training Guidance System was designed and implemented to meet the students' needs for personalized training schemes and improve AG teaching quality. The System can provide convenient ways for scientific training in a targeted and oriented manner on the basis of the differences in physical quality. Also, it can provide teachers with detailed data about the students' physical quality and their AG training; through the visualization of valuable statistical data, it is able to provide a powerful basis for decision makers of teaching departments and thus facilitate the perfection of AG teaching methods.

  3. Series: Practical guidance to qualitative research. Part 1: Introduction.

    Science.gov (United States)

    Moser, Albine; Korstjens, Irene

    2017-12-01

    In the course of our supervisory work over the years, we have noticed that qualitative research tends to evoke a lot of questions and worries, so-called Frequently Asked Questions. This journal series of four articles intends to provide novice researchers with practical guidance for conducting high-quality qualitative research in primary care. By 'novice' we mean Master's students and junior researchers, as well as experienced quantitative researchers who are engaging in qualitative research for the first time. This series addresses their questions and provides researchers, readers, reviewers and editors with references to criteria and tools for judging the quality of papers reporting on qualitative research. This first article describes the key features of qualitative research, provides publications for further learning and reading, and gives an outline of the series.

  4. Deep Energy Retrofit Guidance for the Building America Solutions Center

    Energy Technology Data Exchange (ETDEWEB)

    Less, Brennan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Walker, Iain [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-01-01

    The U.S. DOE Building America program has established a research agenda targeting market-relevant strategies to achieve 40% reductions in existing home energy use by 2030. Deep Energy Retrofits (DERs) are part of the strategy to meet and exceed this goal. DERs are projects that create new, valuable assets from existing residences, by bringing homes into alignment with the expectations of the 21st century. Ideally, high energy using, dated homes that are failing to provide adequate modern services to their owners and occupants (e.g., comfortable temperatures, acceptable humidity, clean, healthy), are transformed through comprehensive upgrades to the building envelope, services and miscellaneous loads into next generation high performance homes. These guidance documents provide information to aid in the broader market adoption of DERs. They are intended for inclusion in the online resource the Building America Solutions Center (BASC). This document is an assemblage of multiple entries in the BASC, each of which addresses a specific aspect of Deep Energy Retrofit best practices for projects targeting at least 50% energy reductions. The contents are based upon a review of actual DERs in the U.S., as well as a mixture of engineering judgment, published guidance from DOE research in technologies and DERs, simulations of cost-optimal DERs, Energy Star and Consortium for Energy Efficiency (CEE) product criteria, and energy codes.

  5. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

    Science.gov (United States)

    Biankin, Andrew V; Waddell, Nicola; Kassahn, Karin S; Gingras, Marie-Claude; Muthuswamy, Lakshmi B; Johns, Amber L; Miller, David K; Wilson, Peter J; Patch, Ann-Marie; Wu, Jianmin; Chang, David K; Cowley, Mark J; Gardiner, Brooke B; Song, Sarah; Harliwong, Ivon; Idrisoglu, Senel; Nourse, Craig; Nourbakhsh, Ehsan; Manning, Suzanne; Wani, Shivangi; Gongora, Milena; Pajic, Marina; Scarlett, Christopher J; Gill, Anthony J; Pinho, Andreia V; Rooman, Ilse; Anderson, Matthew; Holmes, Oliver; Leonard, Conrad; Taylor, Darrin; Wood, Scott; Xu, Qinying; Nones, Katia; Fink, J Lynn; Christ, Angelika; Bruxner, Tim; Cloonan, Nicole; Kolle, Gabriel; Newell, Felicity; Pinese, Mark; Mead, R Scott; Humphris, Jeremy L; Kaplan, Warren; Jones, Marc D; Colvin, Emily K; Nagrial, Adnan M; Humphrey, Emily S; Chou, Angela; Chin, Venessa T; Chantrill, Lorraine A; Mawson, Amanda; Samra, Jaswinder S; Kench, James G; Lovell, Jessica A; Daly, Roger J; Merrett, Neil D; Toon, Christopher; Epari, Krishna; Nguyen, Nam Q; Barbour, Andrew; Zeps, Nikolajs; Kakkar, Nipun; Zhao, Fengmei; Wu, Yuan Qing; Wang, Min; Muzny, Donna M; Fisher, William E; Brunicardi, F Charles; Hodges, Sally E; Reid, Jeffrey G; Drummond, Jennifer; Chang, Kyle; Han, Yi; Lewis, Lora R; Dinh, Huyen; Buhay, Christian J; Beck, Timothy; Timms, Lee; Sam, Michelle; Begley, Kimberly; Brown, Andrew; Pai, Deepa; Panchal, Ami; Buchner, Nicholas; De Borja, Richard; Denroche, Robert E; Yung, Christina K; Serra, Stefano; Onetto, Nicole; Mukhopadhyay, Debabrata; Tsao, Ming-Sound; Shaw, Patricia A; Petersen, Gloria M; Gallinger, Steven; Hruban, Ralph H; Maitra, Anirban; Iacobuzio-Donahue, Christine A; Schulick, Richard D; Wolfgang, Christopher L; Morgan, Richard A; Lawlor, Rita T; Capelli, Paola; Corbo, Vincenzo; Scardoni, Maria; Tortora, Giampaolo; Tempero, Margaret A; Mann, Karen M; Jenkins, Nancy A; Perez-Mancera, Pedro A; Adams, David J; Largaespada, David A; Wessels, Lodewyk F A; Rust, Alistair G; Stein, Lincoln D; Tuveson, David A; Copeland, Neal G; Musgrove, Elizabeth A; Scarpa, Aldo; Eshleman, James R; Hudson, Thomas J; Sutherland, Robert L; Wheeler, David A; Pearson, John V; McPherson, John D; Gibbs, Richard A; Grimmond, Sean M

    2012-11-15

    Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number analysis to define genomic aberrations in a prospectively accrued clinical cohort (n = 142) of early (stage I and II) sporadic pancreatic ductal adenocarcinoma. Detailed analysis of 99 informative tumours identified substantial heterogeneity with 2,016 non-silent mutations and 1,628 copy-number variations. We define 16 significantly mutated genes, reaffirming known mutations (KRAS, TP53, CDKN2A, SMAD4, MLL3, TGFBR2, ARID1A and SF3B1), and uncover novel mutated genes including additional genes involved in chromatin modification (EPC1 and ARID2), DNA damage repair (ATM) and other mechanisms (ZIM2, MAP2K4, NALCN, SLC16A4 and MAGEA6). Integrative analysis with in vitro functional data and animal models provided supportive evidence for potential roles for these genetic aberrations in carcinogenesis. Pathway-based analysis of recurrently mutated genes recapitulated clustering in core signalling pathways in pancreatic ductal adenocarcinoma, and identified new mutated genes in each pathway. We also identified frequent and diverse somatic aberrations in genes described traditionally as embryonic regulators of axon guidance, particularly SLIT/ROBO signalling, which was also evident in murine Sleeping Beauty transposon-mediated somatic mutagenesis models of pancreatic cancer, providing further supportive evidence for the potential involvement of axon guidance genes in pancreatic carcinogenesis.

  6. An evaluation of two guidance programmes to promote breast-feeding

    Directory of Open Access Journals (Sweden)

    M. Steyn

    1989-09-01

    Full Text Available During the past ten years a comprehensive research project has been undertaken to develop a guidance programme in three adjacent communities in the South- Western Cape with the aim o f lowering the high incidence o f coronary heart disease. The purpose o f this substudy was to determine whether the guidance provided in the different communities had any influence on the knowledge o f and attitudes towards the nutrition o f pregnant women, babies and infants as well as breast-feeding practices o f the women who gave birth during the period 1980 to 1986. In the first community guidance was provided by means o f small mass media and interpersonal communication whereas only the small mass media were employed in the second. The third served as the control community. The findings suggest that the combined interpersonal and mass media programme was more successful than the mass media programme alone.

  7. Pollution Control Guidance for Geothermal Energy Development

    Energy Technology Data Exchange (ETDEWEB)

    Hartley, Robert P.

    1978-06-01

    This report summarizes the EPA regulatory approach toward geothermal energy development. The state of knowledge is described with respect to the constituents of geothermal effluents and emissions, including water, air, solid wastes, and noise. Pollutant effects are discussed. Pollution control technologies that may be applicable are described along with preliminary cost estimates for their application. Finally discharge and emission limitations are suggested that may serve as interim guidance for pollution control during early geothermal development.

  8. Long-Term Stewardship Baseline Report and Transition Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Kristofferson, Keith

    2001-11-01

    Long-term stewardship consists of those actions necessary to maintain and demonstrate continued protection of human health and the environment after facility cleanup is complete. As the Department of Energy’s (DOE) lead laboratory for environmental management programs, the Idaho National Engineering and Environmental Laboratory (INEEL) administers DOE’s long-term stewardship science and technology efforts. The INEEL provides DOE with technical, and scientific expertise needed to oversee its long-term environmental management obligations complexwide. Long-term stewardship is administered and overseen by the Environmental Management Office of Science and Technology. The INEEL Long-Term Stewardship Program is currently developing the management structures and plans to complete INEEL-specific, long-term stewardship obligations. This guidance document (1) assists in ensuring that the program leads transition planning for the INEEL with respect to facility and site areas and (2) describes the classes and types of criteria and data required to initiate transition for areas and sites where the facility mission has ended and cleanup is complete. Additionally, this document summarizes current information on INEEL facilities, structures, and release sites likely to enter long-term stewardship at the completion of DOE’s cleanup mission. This document is not intended to function as a discrete checklist or local procedure to determine readiness to transition. It is an overarching document meant as guidance in implementing specific transition procedures. Several documents formed the foundation upon which this guidance was developed. Principal among these documents was the Long-Term Stewardship Draft Technical Baseline; A Report to Congress on Long-Term Stewardship, Volumes I and II; Infrastructure Long-Range Plan; Comprehensive Facility Land Use Plan; INEEL End-State Plan; and INEEL Institutional Plan.

  9. Education, consultation, guidance, students, advisor, teacher

    Directory of Open Access Journals (Sweden)

    M Seyedmajidi

    2013-09-01

    Full Text Available Introduction: Student counseling and supervision play an important role to overcome learning problems and to achieve educational goals. The present study is intended to investigate viewpoints of students regarding educational guidance and advice studying at Babol University of Medical Sciences. Methods: In this descriptive cross-sectional survey, viewpoints of 480 students were collected by a questionnaire. The validity and reliability of the questionnaire had been approved before. Data were analyzed using SPSS version 17 software. Chi- square and ANOVA tests were administered. Results: 61.2% of all participants were female and 38.8% were males with mean age of 21.3±4.0. 37.2% of these students lacked sufficient knowledge and information on how to request from their advisors for help and guidance. Half of students (50.3% reported attendance of advisors and holding routine consultation is inappropriate. Advisors made more educational files for females compare to males (P=0.001. No difference observed regarding educational disciplines of the advisors regarding students were dissatisfied with help and guidance received from paramedics and dentistry students in most fields (87.3% and 81.5% respectively. Conclusion: It seems that either student has no sufficient information about tasks of advisors and/or advisors may not do their tasks properly. It is recommended the students to be acquainted with advisors’ tasks upon their entrance into the university. Training classes for new academics would be helpful.

  10. Draft Guidance for Protective Action Strategies Development

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sang Hyun; Jeong, Seung Young; Kim, Wanjoo [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2016-10-15

    National nuclear emergency preparedness and response (EPR) framework has been improved since the Fukushima accident in 2011. There are still many needs to be amended and improved in regulatory requirements and technical criteria to warrant efficacy of the EPR framework. As an important part of the framework, protective actions have to be implemented with optimized and justified manner during whole emergency phases. In this study, to enhance protective action strategies in response to severe accident or general emergency, existing procedures were reviewed. And generic guidance to develop protective action recommendations (PARs) was proposed considering revised EPZ and recent technical information on protective action strategies. The generic guidance for PARs based on facility status was introduced. Revision of EPZ and some recent information on protective action strategies, such as staged evacuation, specific approach for rapidly progressing accident were considered. It would be employed as a basis to develop site-specific strategies of PARs and regulatory guidance for emergency plan by nuclear licensee. It was focused on an early phase of nuclear emergency. Further efforts to develop site specific strategies of PARs and strategies which cover full range of nuclear emergency would be followed by several stake holders.

  11. The evolution: Handwashing to hand hygiene guidance.

    Science.gov (United States)

    Bjerke, Nancy B

    2004-01-01

    Handwashing is a fundamental principle and practice in the prevention, control, and reduction of healthcare-acquired infection. Advocated by Semmelweiss (Nursing, The Finest Art: An Illustrated History. St Louis: Mosby; 1985:204) from the 1800s to resolve an obstetric morbidity and mortality occurrence, the simple act of hand cleansing portrays the intuitive benefits to basic hygiene, health continuum, and, most important, disease prevention. According to recently published guidance (MMWR Morb Mortal Wkly Rep. October 25, 2002;51:32-34), the term handwashing is replaced by the new term hand hygiene, which includes hand cleansing, hand disinfecting, and surgical hand scrub. This article focuses on the published guidance, blending the salient aspects of hand hygiene practices from noted champions, reinforcing the aesthetics of meticulous cleansing, to guidance on its practice in healthcare settings. In healthcare, the principle of "clean hands are healing hands" bears value and demands compliance in order to prevent and control infectious processes while protecting the person from acquiring infectious diseases.

  12. Quantitative Decision Support Requires Quantitative User Guidance

    Science.gov (United States)

    Smith, L. A.

    2009-12-01

    Is it conceivable that models run on 2007 computer hardware could provide robust and credible probabilistic information for decision support and user guidance at the ZIP code level for sub-daily meteorological events in 2060? In 2090? Retrospectively, how informative would output from today’s models have proven in 2003? or the 1930’s? Consultancies in the United Kingdom, including the Met Office, are offering services to “future-proof” their customers from climate change. How is a US or European based user or policy maker to determine the extent to which exciting new Bayesian methods are relevant here? or when a commercial supplier is vastly overselling the insights of today’s climate science? How are policy makers and academic economists to make the closely related decisions facing them? How can we communicate deep uncertainty in the future at small length-scales without undermining the firm foundation established by climate science regarding global trends? Three distinct aspects of the communication of the uses of climate model output targeting users and policy makers, as well as other specialist adaptation scientists, are discussed. First, a brief scientific evaluation of the length and time scales at which climate model output is likely to become uninformative is provided, including a note on the applicability the latest Bayesian methodology to current state-of-the-art general circulation models output. Second, a critical evaluation of the language often employed in communication of climate model output, a language which accurately states that models are “better”, have “improved” and now “include” and “simulate” relevant meteorological processed, without clearly identifying where the current information is thought to be uninformative and misleads, both for the current climate and as a function of the state of the (each) climate simulation. And thirdly, a general approach for evaluating the relevance of quantitative climate model output

  13. 78 FR 12761 - Guidance for Industry: Guidance on the Labeling of Certain Uses of Lecithin Derived From Soy...

    Science.gov (United States)

    2013-02-25

    ... HUMAN SERVICES Food and Drug Administration (formerly 2006D-0169) Guidance for Industry: Guidance on the Labeling of Certain Uses of Lecithin Derived From Soy Under Section 403(w) of the Federal Food, Drug, and Cosmetic Act; Withdrawal of Guidance AGENCY: Food and Drug Administration, HHS. ACTION: Notice; withdrawal...

  14. European Lifelong Guidance Policy Network Representatives' Conceptions of the Role of Information and Communication Technologies Related to National Guidance Policies

    Science.gov (United States)

    Kettunen, Jaana; Vuorinen, Raimo; Ruusuvirta, Outi

    2016-01-01

    This article reports findings from a phenomenographic investigation into European Lifelong Guidance Policy Network representatives' conceptions of the role of information and communication technologies (ICT) related to national lifelong guidance policies. The role of ICT in relation to national lifelong guidance policies was conceived as (1)…

  15. 76 FR 29251 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls; Guidance...

    Science.gov (United States)

    2011-05-20

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff...). The document announced the availability of the guidance entitled ``Guidance for Industry and Food and...; Correction AGENCY: Food and Drug Administration, HHS. ACTION: Notice; correction. SUMMARY: The Food and Drug...

  16. 76 FR 44594 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Science.gov (United States)

    2011-07-26

    .... Electronic Access Persons interested in obtaining a copy of the guidance may do so by using the Internet. A... the SUPPLEMENTARY INFORMATION section for information on electronic access to the guidance. Submit...), under section 513(f)(2) of the FD&C Act. II. Significance of Special Controls Guidance FDA believes that...

  17. Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals.

    Science.gov (United States)

    Elsinga, Philip; Todde, Sergio; Penuelas, Ivan; Meyer, Geerd; Farstad, Brit; Faivre-Chauvet, Alain; Mikolajczak, Renata; Westera, Gerrit; Gmeiner-Stopar, Tanja; Decristoforo, Clemens

    2010-05-01

    This guidance is meant as a guidance to Part B of the EANM "Guidelines on Good Radiopharmacy Practice (GRPP)" issued by the Radiopharmacy Committee of the EANM (see www.eanm.org ), covering the small-scale "in house" preparation of radiopharmaceuticals which are not kit procedures. The aim is to provide more detailed and practice-oriented guidance to those who are involved in the small-scale preparation of, for example, PET, therapeutic or other radiopharmaceuticals which are not intended for commercial purposes or distribution.

  18. Guidance and Control Software Project Data - Volume 4: Configuration Management and Quality Assurance Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes configuration management and quality assurance documents from the GCS project. Volume 4 contains six appendices: A. Software Accomplishment Summary for the Guidance and Control Software Project; B. Software Configuration Index for the Guidance and Control Software Project; C. Configuration Management Records for the Guidance and Control Software Project; D. Software Quality Assurance Records for the Guidance and Control Software Project; E. Problem Report for the Pluto Implementation of the Guidance and Control Software Project; and F. Support Documentation Change Reports for the Guidance and Control Software Project.

  19. Putting the t in tools: a roadmap for implementation of new global and regional transgender guidance.

    Science.gov (United States)

    Wolf, R Cameron; Adams, Darrin; Dayton, Robyn; Verster, Annette; Wong, Joe; Romero, Marcela; Mazin, Rafael; Settle, Edmund; Sladden, Tim; Keatley, JoAnne

    2016-01-01

    Transgender (trans) activists and global health partners have collaborated to develop new tools and guidance for assessing and addressing HIV and other health needs within trans populations. Trans women experience a heavy burden of HIV and other sexually transmitted infections (STIs), high incidence of violence and difficulties accessing gender-affirming services. At the same time, little has been published on trans men's health, HIV issues, needs and experiences. Young trans people are especially marginalized and vulnerable, with few programmes and services specifically tailored to their needs. Trans-specific data and guidance are needed to adapt the global response to HIV to meet the needs of the trans population. While the needs of this group have only recently received attention, global, regional and other technical guidance documents are being developed to address these gaps. Regional blueprints for comprehensive care for trans people in Latin America, the Caribbean, and Asia and the Pacific are now available. These tools - supported by the Pan American Health Organization, World Health Organization, US President's Emergency Plan for AIDS Relief and the United Nations Development Programme, in collaboration with regional trans groups - provide a contextual map, indicating opportunities for interventions in health, HIV, violence, stigma and discrimination, social protection and human rights. Global guidance includes the World Health Organization's Policy Brief: Transgender People and HIV, and the interagency publication, Implementing Comprehensive HIV and STI Programmes with Transgender People. Community empowerment and capacity building are the focus of the new tools for global and regional transgender guidance. The goal is to strengthen and ensure community-led responses to the HIV challenge in trans populations. This article describes the new tools and guidance and considers the steps needed to use them to appropriately support and engage transgender

  20. Human-system Interfaces to Automatic Systems: Review Guidance and Technical Basis

    Energy Technology Data Exchange (ETDEWEB)

    OHara, J.M.; Higgins, J.C.

    2010-01-31

    Automation has become ubiquitous in modern complex systems and commercial nuclear power plants are no exception. Beyond the control of plant functions and systems, automation is applied to a wide range of additional functions including monitoring and detection, situation assessment, response planning, response implementation, and interface management. Automation has become a 'team player' supporting plant personnel in nearly all aspects of plant operation. In light of the increasing use and importance of automation in new and future plants, guidance is needed to enable the NRC staff to conduct safety reviews of the human factors engineering (HFE) aspects of modern automation. The objective of the research described in this report was to develop guidance for reviewing the operator's interface with automation. We first developed a characterization of the important HFE aspects of automation based on how it is implemented in current systems. The characterization included five dimensions: Level of automation, function of automation, modes of automation, flexibility of allocation, and reliability of automation. Next, we reviewed literature pertaining to the effects of these aspects of automation on human performance and the design of human-system interfaces (HSIs) for automation. Then, we used the technical basis established by the literature to develop design review guidance. The guidance is divided into the following seven topics: Automation displays, interaction and control, automation modes, automation levels, adaptive automation, error tolerance and failure management, and HSI integration. In addition, we identified insights into the automaton design process, operator training, and operations.