Title IX: With New Opportunities, Girls' Interest Rises

Science.gov (United States)

Toporek, Bryan

2012-01-01

On June 23, 1972, President Richard M. Nixon signed into law Title IX of the Education Amendments of 1972, which prohibits gender discrimination in any federally financed education program or activity. Title IX is far-reaching, but the law is most often associated with school and college athletics. Title IX allows schools to prove their athletic…

Report on the BIAPWS 2009 symposium on power plant chemistry

Energy Technology Data Exchange (ETDEWEB)

Bignold, Geoff [GJB Chemistry for Power Ltd., Ashtead, Surrey, (United Kingdom)

2009-06-15

The British and Irish Association for the Properties of Water and Steam held a Workshop on Chemical Aspects of Flexible Operation of Plant and a Symposium on Environmental and Operational Issues on 21-22 April 2009 at Beeston, Nottingham. Summaries of the eight papers presented at the symposium are provided. (orig.)

Arabidopsis Lectin Receptor Kinases LecRK-IX.1 and LecRK-IX.2 Are Functional Analogs in Regulating Phytophthora Resistance and Plant Cell Death.

Science.gov (United States)

Wang, Yan; Cordewener, Jan H G; America, Antoine H P; Shan, Weixing; Bouwmeester, Klaas; Govers, Francine

2015-09-01

L-type lectin receptor kinases (LecRK) are potential immune receptors. Here, we characterized two closely-related Arabidopsis LecRK, LecRK-IX.1 and LecRK-IX.2, of which T-DNA insertion mutants showed compromised resistance to Phytophthora brassicae and Phytophthora capsici, with double mutants showing additive susceptibility. Overexpression of LecRK-IX.1 or LecRK-IX.2 in Arabidopsis and transient expression in Nicotiana benthamiana increased Phytophthora resistance but also induced cell death. Phytophthora resistance required both the lectin domain and kinase activity, but for cell death, the lectin domain was not needed. Silencing of the two closely related mitogen-activated protein kinase genes NbSIPK and NbNTF4 in N. benthamiana completely abolished LecRK-IX.1-induced cell death but not Phytophthora resistance. Liquid chromatography-mass spectrometry analysis of protein complexes coimmunoprecipitated in planta with LecRK-IX.1 or LecRK-IX.2 as bait, resulted in the identification of the N. benthamiana ABC transporter NbPDR1 as a potential interactor of both LecRK. The closest homolog of NbPDR1 in Arabidopsis is ABCG40, and coimmunoprecipitation experiments showed that ABCG40 associates with LecRK-IX.1 and LecRK-IX.2 in planta. Similar to the LecRK mutants, ABCG40 mutants showed compromised Phytophthora resistance. This study shows that LecRK-IX.1 and LecRK-IX.2 are Phytophthora resistance components that function independent of each other and independent of the cell-death phenotype. They both interact with the same ABC transporter, suggesting that they exploit similar signal transduction pathways.

Action of the protoporphyrin-Ix (Pp-Ix) in the life period of Drosophila mutants deficient in endogenous antioxidants

International Nuclear Information System (INIS)

Vidal E, L. M.

2012-01-01

The human being is daily exposed to free radicals or reactive oxygen species (Ros), as a result of the breathing and the interactions with xenobiotics that can cause irreversible lesions in molecules and cellular structures and that they are associated to diseases like the cancer, neuro degenerative and to the acceleration of the normal process of aging. Fortunately, to reduce the damaging effect of the Ros the cell has endogenous antioxidant systems constituted by antioxidant enzymes as: the superoxide dismutase (Sod), the catalase (Cat), and the glutathione peroxidase and reductase. Even, when these systems are not enough, we find to the exogenous antioxidants that cooperate in the balance of the Ros, as the porphyrins that include to the chlorophyllin, the hemin and the bilirubin among others. The protoporphyrin-Ix (Pp-Ix) is a tetra pyrrole without metallic center with antimutagenic and antioxidant activity similar to that of the chlorophyllin. However, is also known that their over-expression has toxic effects, because induces Ros. In Drosophila melanogaster, recently was found that the Pp-Ix have dual action anti and persistent mutagenic. One of their possible mechanism to act like mutagen is through the Ros induction. To evaluate this possibility and based in that the increase in the Ros levels can accelerate the aging process, in the present work the Pp-Ix role was evaluated, in the life period of Drosophila melanogaster strains deficient in Sod and Cat, sensitive to radiation or oxidative stress (rad, whd and flr 3 ) and a wild one as control (C-S). Females and males of each strain were treated chronically for separate with sucrose or Pp-Ix and every 15 days a group of each sex was irradiated with 10 Gy of gamma rays. The results indicated that the chronic treatment with Pp-Ix and in combination with radiation, increased the life period of the C-S strain. The Sod strain had a contrary effect and this effect was pronounced with the combined treatment of Pp-Ix

Synthesis of indium-111 mesoprotoporphyrin IX

International Nuclear Information System (INIS)

Lee, K.M.; Marshall, A.G.

1981-01-01

Indium-111 mesoprotoporphyrin IX has been prepared by refluxing suitable proportions of InCl 3 , sodium acetate, and mesoprotoporphyrin IX in glacial acetic acid. The labeled metalloporphyrin is sufficiently water-soluble for use as a scanning agent, and can also be incorporated into heme apoproteins for perturbed gamma-gamma angular correlation measurements. (author)

IX - MR Control Chart as a Tool in Assessment of the Cast Iron Properties Stability

Directory of Open Access Journals (Sweden)

F. Binczyk

2007-07-01

Full Text Available The study offers a statistical assessment of the stability of a technological process of melting and pouring low-carbon grey iron assigned for casting of brake discs. Some specific characteristics were presented that should be taken into consideration when statistical methods are used for technology improvement. The stability of the cast iron melting process was evaluated using data read out from the thermal analysis curve and true data, i.e. the results of spectrometric analysis of the chemical composition and measured values of the mechanical properties. The method for assessment of process stability was discussed on the example of carbon content and Brinell hardness. The examined parameters of the technological process of grey iron melting and casting are independent of each other (the results of carbon content determination in successive melts, the results of hardness measurements, etc.. Therefore, for analysis, the IX - MR type charts were chosen, where single measurements of the selected property (n = 1 serve as a measure of location, while a measure of variability are the, so called, Moving Ranges (MR, which are an absolute value of the difference between the two successive measurements.

Labeled factor IX kinetics in patients with hemophilia-B

International Nuclear Information System (INIS)

Smith, K.J.; Thompson, A.R.

1981-01-01

Labeled factor IX was infused five time into four patients with hemophilia-B. Ten-minute plasma recovery average 35% (SD +/- 2) and the mean T 1/2 beta-phase elimination was 23 hr (+/- 5). No alteration in the postinfusion 125I-factor-IX could be detected by radioautography of plasma samples run on polyacrylamide gels or on crossed-immunoelectrophoresis. Label was excreted into the urine as free 125I-iodide. Kinetics were similar when the labeled preparation was infused alone or with a commercial concentrate containing unlabeled factor IX. Infusion of factor IX in man is best described by a two-compartment open pharmacokinetic model where factor IX is distributed in a space larger than the plasma volume

Compact invariant sets of the Bianchi VIII and Bianchi IX Hamiltonian systems

International Nuclear Information System (INIS)

Starkov, Konstantin E.

2011-01-01

In this Letter we prove that all compact invariant sets of the Bianchi VIII Hamiltonian system are contained in the set described by several simple linear equalities and inequalities. Moreover, we describe invariant domains in which the phase flow of this system has no recurrence property and show that there are no periodic orbits and neither homoclinic, nor heteroclinic orbits contained in the zero level set of its Hamiltonian. Similar results are obtained for the Bianchi IX Hamiltonian system. -- Highlights: → Zero level set of Hamiltonian of Bianchi VIII/IX systems contains no periodic orbits. → Similar conditions for homoclinic/heteroclinic orbits are given. → General nonexistence conditions of compact invariant sets are got.

Compact invariant sets of the Bianchi VIII and Bianchi IX Hamiltonian systems

Energy Technology Data Exchange (ETDEWEB)

Starkov, Konstantin E., E-mail: konst@citedi.mx [CITEDI-IPN, Av. del Parque 1310, Mesa de Otay, Tijuana, BC (Mexico)

2011-08-22

In this Letter we prove that all compact invariant sets of the Bianchi VIII Hamiltonian system are contained in the set described by several simple linear equalities and inequalities. Moreover, we describe invariant domains in which the phase flow of this system has no recurrence property and show that there are no periodic orbits and neither homoclinic, nor heteroclinic orbits contained in the zero level set of its Hamiltonian. Similar results are obtained for the Bianchi IX Hamiltonian system. -- Highlights: → Zero level set of Hamiltonian of Bianchi VIII/IX systems contains no periodic orbits. → Similar conditions for homoclinic/heteroclinic orbits are given. → General nonexistence conditions of compact invariant sets are got.

Factor IX assay

Science.gov (United States)

... this page: //medlineplus.gov/ency/article/003679.htm Factor IX assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

Proceedings of the ninth symposium on thermophysical properties: special symposium Issue 5

International Nuclear Information System (INIS)

Anon.

1986-01-01

Among the topics discussed in this volume of the symposium are: the establishment of accuracy limits and standards for comparative thermal conductivity measurements; thermal conductivity and electrical resistivity of cadmium arsenide in the temperature range 4.2-40 K; suggestions regarding thermal diffusivity measurements on pyrolytic graphite and pyrolytic boron nitride by the laser pulse method; experimental study of the viscosity of lithium vapor at high temperatures and pressures; transport coefficients of fluid mixtures; an equation of state for isobutane-isopentane mixtures with corrections for impurities, and the importance of thermophysical data in process simulation

Eleventh symposium on energy engineering sciences: Proceedings

International Nuclear Information System (INIS)

1993-01-01

The Eleventh Symposium on Energy Engineering Sciences was held on May 3--5, 1993, at the Argonne National Laboratory, Argonne, Illinois. These proceedings include the program, list of participants, and the papers that were presented during the eight technical sessions held at this meeting. This symposium was organized into eight technical sessions: Surfaces and interfaces; thermophysical properties and processes; inelastic behavior; nondestructive characterization; multiphase flow and thermal processes; optical and other measurement systems; stochastic processes; and large systems and control. Individual projects were processed separately for the databases

2016 AMS Mario J. Molina Symposium

Energy Technology Data Exchange (ETDEWEB)

Zhang, Renyi [Texas A & M Univ., College Station, TX (United States)

2016-11-29

A named symposium to honor Dr. Mario J. Molina was held 10–14 January 2016, as part of the 96th American Meteorological Society (AMS) Annual Meeting in New Orleans, Louisiana. Dr. Molina first demonstrated that industrially produced chlorofluorocarbons (CFCs) decompose in the stratosphere and release chlorine atoms, leading to catalytic ozone destruction. His research in stratospheric chemistry was instrumental to the establishment of the 1987 United Nations Montreal Protocol to ban ozone-depleting substances worldwide. Dr. Molina’s contributions to preserving the planet Earth not only save the atmospheric ozone layer, but also protect the climate by reducing the emissions of greenhouse gases. He was awarded the 1995 Nobel Prize in Chemistry for his pioneering research in understanding the stratospheric ozone loss mechanism. In 2013, President Barack Obama announced Dr. Molina as a recipient of the Presidential Medal of Freedom. The 2016 AMS Molina Symposium honored Dr. Molina’s distinguished contributions to research related to atmospheric chemistry. The symposium contained an integrated theme related to atmospheric chemistry, climate, and policy. Dr. Molina delivered a keynote speech at the Symposium. The conference included invited keynote speeches and invited and contributed oral and poster sessions, and a banquet was held on Tuesday January 12, 2016. The symposium covered all aspects of atmospheric chemistry, with topics including (1) Stratospheric chemistry, (2) Tropospheric chemistry, (3) Aerosol nucleation, growth, and transformation, (4) Aerosol properties, (5) Megacity air pollution, and (6) Atmospheric chemistry laboratory, field, and modeling studies. This DOE project supported 14 scientists, including graduate students, post docs, junior research scientists, and non-tenured assistant professors to attend this symposium.

Evaluation of factor IX deficiency by interdigitated electrode (IDE)

Science.gov (United States)

Gopinath, Subash C. B.; Hashim, Uda; Uda, M. N. A.

2017-03-01

Factor IX deficiency is the main cause of hemophilia A and B. This a severe excessive bleeding disorder that can even kill the patient if not treated with the right prescription of Factor IX hormone to stop the bleeding. The bleeding can be caused by an injury or even a sudden bleeding in some very rare cases. To find the Factor IX effectiveness and to understand the deficiency more carefully for the future of medicine, experiments are conducted to test the Factor IX using the Interdigitated Electrode (IDE) and gold Nanoparticle with the help of Nanoelectrical technology.

Comparison of nitric oxide binding to different pure and mixed protoporphyrin IX monolayers

NARCIS (Netherlands)

Knoben, W.; Crego-Calama, M.; Brongersma, S.H.

2012-01-01

The nitric oxide (NO) binding properties of monolayers of four different protoporphyrins IX adsorbed on aluminum oxide surfaces have been investigated. XPS and AFM results are consistent with the presence of a monolayer of porphyrins, bound to the surface by their carboxylic acid groups and with the

Proceedings of the symposium on nitride fuel cycle technology

International Nuclear Information System (INIS)

2004-12-01

This report is the Proceedings of the Symposium of Nitride Fuel Cycle Technology, which was held on July 28, 2004, at the Tokai Research Establishment of the Japan Atomic Energy Research Institute. The purpose of this symposium is to exchange information and views on nitride fuel cycle technology among researchers from foreign and domestic organizations, and to discuss the recent and future research activities. The topics in the symposium are Present State of the Technology Development in the World and Japan, Fabrication Technology, Property Measurement and Pyrochemical Process. The intensive discussion was made among 53 participants. This report consists of 2 papers as invited presentations and 12 papers as contributed papers. (author)

Symposium 2 of JENAM

CERN Document Server

Pasquali, Anna; Environment and the Formation of Galaxies : 30 years later

2011-01-01

The publication of the morphology - density relation by Alan Dressler in 1980 brought into the limelight the role played by environment in the formation and evolution of galaxies. The symposium Environment and the Formation of Galaxies: 30 years later, was organised with the purpose of establishing the environmental impact on the evolution of galaxies and its dependence on look-back time. Special emphasis was placed on the physical mechanisms that are responsible for transforming galaxies once they are accreted by a group or a cluster, including the observable imprint left in the galaxy HI distribution. Other major topics of the symposium were the environmental dependence of galaxy properties at z ≥ 1 and the implementation of environmental effects in cosmological models of galaxy formation and evolution. This book presents the edited proceedings of this stimulating meeting.

77 FR 64401 - Order of Succession for HUD Region IX

Science.gov (United States)

2012-10-19

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [FR-5550-D-12] Order of Succession for HUD Region IX... Field Offices (Region IX). This Order of Succession supersedes all previous Orders of Succession for HUD Region IX. DATES: Effective Date: October 9, 2012. FOR FURTHER INFORMATION CONTACT: Lawrence D. Reynolds...

Intrinsic thermodynamics of inhibitor binding to human carbonic anhydrase IX.

Science.gov (United States)

Linkuvienė, Vaida; Matulienė, Jurgita; Juozapaitienė, Vaida; Michailovienė, Vilma; Jachno, Jelena; Matulis, Daumantas

2016-04-01

Human carbonic anhydrase 9th isoform (CA IX) is an important marker of numerous cancers and is increasingly interesting as a potential anticancer drug target. Various synthetic aromatic sulfonamide-bearing compounds are being designed as potent inhibitors of CA IX. However, sulfonamide compound binding to CA IX is linked to several reactions, the deprotonation of the sulfonamide amino group and the protonation of the CA active site Zn(II)-bound hydroxide. These linked reactions significantly affect the affinities and other thermodynamic parameters such as enthalpies and entropies of binding. The observed and intrinsic affinities of compound binding to CA IX were determined by the fluorescent thermal shift assay. The enthalpies and entropies of binding were determined by the isothermal titration calorimetry. The pKa of CA IX was determined to be 6.8 and the enthalpy of CA IX-Zn(II)-bound hydroxide protonation was -24 kJ/mol. These values enabled the analysis of intrinsic thermodynamics of a library of compounds binding to CA IX. The most strongly binding compounds exhibited the intrinsic affinity of 0.01 nM and the observed affinity of 2 nM. The intrinsic thermodynamic parameters of compound binding to CA IX helped to draw the compound structure to thermodynamics relationship. It is important to distinguish the intrinsic from observed parameters of any disease target protein interaction with its inhibitors as drug candidates when drawing detailed compound structure to thermodynamics correlations. Copyright © 2016 Elsevier B.V. All rights reserved.

11. European cosmic ray symposium

International Nuclear Information System (INIS)

1989-03-01

The biannual Symposium includes all aspects of cosmic ray research. The scientific programme was organized under three main headings: Cosmic rays in the heliosphere, Cosmic rays in the interstellar and extragalactic space, Properties of high-energy interactions as studied by cosmic rays. Seven invited talks were indexed seprately for the INIS database. (R.P.)

14. European cosmic ray symposium. Symposium program and abstracts

International Nuclear Information System (INIS)

1994-08-01

The abstracts of the 14. European Cosmic Ray Symposium are presented. The papers cover a large variety of topics in cosmic ray physics, both from the theoretical and the experimental point of view. Sun physics, and the effects on the inner heliosphere, the composition, and the properties of the primary and secondary cosmic radiation, galactic acceleration and the results of accelerator physics relevant to cosmic radiation physics, and the description and the results of large detector systems are presented. 63 items are indexed for INIS database. (K.A.)

An update on anticancer drug development and delivery targeting carbonic anhydrase IX

Directory of Open Access Journals (Sweden)

Justina Kazokaitė

2017-11-01

Full Text Available The expression of carbonic anhydrase (CA IX is up-regulated in many types of solid tumors in humans under hypoxic and acidic microenvironment. Inhibition of CA IX enzymatic activity with selective inhibitors, antibodies or labeled probes has been shown to reverse the acidic environment of solid tumors and reduce the tumor growth establishing the significant role of CA IX in tumorigenesis. Thus, the development of potent antitumor drugs targeting CA IX with minimal toxic effects is important for the target-specific tumor therapy. Recently, several promising antitumor agents against CA IX have been developed to treat certain types of cancers in combination with radiation and chemotherapy. Here we review the inhibition of CA IX by small molecule compounds and monoclonal antibodies. The methods of enzymatic assays, biophysical methods, animal models including zebrafish and Xenopus oocytes, and techniques of diagnostic imaging to detect hypoxic tumors using CA IX-targeted conjugates are discussed with the aim to overview the recent progress related to novel therapeutic agents that target CA IX in hypoxic tumors.

The importance of protoporphyrin IX efflux for ALA-PDT dosimetry

International Nuclear Information System (INIS)

Milanetto, M C; Imasato, H; Perussi, J R

2009-01-01

One of the major advances in PDT is the use of 5-aminolevulinic acid (ALA) to induce the production of an endogenous photosensitizer inside the cells using intracellular enzymatic pathways. ALA is the first intermediate in heme biosynthesis and a precursor of the protoporphyrin IX (PpIX). When activated by light, this efficient photosensitizer accumulated in the target cells can produce cytotoxicity. The aim of this study was to find the best conditions for cell killing using ALA to temporarily increase the concentration of PpIX in two cell lines. It was shown that a considerable efflux of synthesized PpIX occurs. Since this efflux is time-dependent, it is essential to know the optimum time for irradiation after ALA administration. So, the efflux of PpIX from the cells is an important parameter to be considered for ALA-PDT dosimetry

Analysis of cell line variation in biochemical production of protoporphyrin IX

Science.gov (United States)

Gibbs, Summer L.; Chen, Bin; O'Hara, Julia A.; Hoopes, P. Jack; Hasan, Tayyaba; Pogue, Brian W.

2006-02-01

Protoporphyrin IX (PpIX) is produced via the heme synthesis pathway by the cell following administration of aminolevulinic acid (ALA). ALA synthase, the enzyme that produces ALA in the cell from glycine and succinyl-coenzyme A, is inhibited in a feedback mechanism by heme and thus is the rate limiting enzyme in the heme synthesis pathway. Since ALA is administered systemically, the rate limiting step that naturally exists in the cells is bypassed, however it is currently unclear why cells have different rate limiting steps in the ALA-PpIX synthesis pathway, and more specifically which types of cancer cells are most productive. It has been determined that when the same amount of ALA is administered to a wide panel of cancer cells in vitro that vastly differing amounts of PpIX are produced. The steps for the ALA-PpIX pathway occur in and around the mitochondria of the cell, but interestingly no correlation is seen between PpIX production and mitochondrial content of the cell, following ALA administration. However, total cell area shows positive correlation with PpIX production. Administration of the iron chelator, 1,2-dimethyl-3-hydroxy-4-pyridone (L1) in combination with ALA allows the final step in the heme synthesis pathway, conversion of PpIX to heme, to be delayed and thus increases the detectable amount of PpIX in each cell line. The cell lines that have the lowest PpIX production following administration of ALA alone show the largest increase in production following the combined administration of ALA and L1. PpIX fluorescence is thought to be a measure of cellular activity and the goal of the current study was to determine which cell lines would be the most promising targets for fluorescence detection or monitoring response to therapy. The results indicate that the cells with larger size and larger numbers of mitochondria may be good potential targets for this therapy. While this conclusion may appear obvious, it is not universally true, and cellular specific

Effect of IX dosing on polypropylene and PVDF membrane fouling control

KAUST Repository

Myat, Darli Theint

2013-07-01

The performance of ion exchange (IX) resin for organics removal from wastewater was assessed using advanced characterisation techniques for varying doses of IX. Organic characterisation using liquid chromatography with a photodiode array (PDA) and fluorescence spectroscopy (Method A), and UV254, organic carbon and organic nitrogen detectors (Method B), was undertaken on wastewater before and after magnetic IX treatment. Results showed partial removal of the biopolymer fraction at high IX doses. With increasing concentration of IX, evidence for nitrogen-containing compounds such as proteins and amino acids disappeared from the LC-OND chromatogram, complementary to the fluorescence response. A greater fluorescence response of tryptophan-like proteins (278nm/343nm) for low IX concentrations was consistent with aggregation of tryptophan-like compounds into larger aggregates, either by self-aggregation or with polysaccharides. Recycling of IX resin through multiple adsorption steps without regeneration maintained the high level of humics removal but there was no continued removal of biopolymer. Subsequent membrane filtration of the IX treated waters resulted in complex fouling trends. Filtration tests with either polypropylene (PP) or polyvinylidene fluoride (PVDF) membranes showed higher rates of initial fouling following treatment with high IX doses (10mL/L) compared to filtration of untreated water, while treatment with lower IX doses resulted in decreased fouling rates relative to the untreated water. However, at longer filtration times the rate of fouling of IX treated waters was lower than untreated water and the relative fouling rates corresponded to the amount of biopolymer material in the feed. It was proposed that the mode of fouling changed from pore constriction during the initial filtration period to filter cake build up at longer filtration times. The organic composition strongly influenced the rate of fouling during the initial filtration period due to

Noninvasive murine glioma detection improved following photobleaching of skin PpIX fluorescence

Science.gov (United States)

Gibbs-Strauss, Summer L.; Davis, Scott C.; O'Hara, Julia A.; Hoopes, P. Jack; Hasan, Tayyaba; Pogue, Brian W.

2008-02-01

Aminolevulinic Acid (ALA) is a prodrug which can be administered to cells, animals or patients after which it is transformed via the Heme synthesis pathway into the fluorescent molecule Protoporphyrin IX (PpIX). PpIX has been shown to be useful as both a photosensitizer for photodynamic therapy (PDT) and as a fluorescence imaging contrast agent. The ALA-PpIX system not only provides contrast for fluorescence imaging but also gives information about the metabolic activity of the imaged tissue and thus could be useful for monitoring cancer therapy. In the current study skin photobleaching was examined to determine if PpIX fluorescence contrast in malignant brain tumors could be better visualized noninvasively. Red light photobleaching decreased skin PpIX fluorescence and increased the ability to noninvasively quantify PpIX fluorescence in murine gliomas, as in vivo measurements of mean PpIX fluorescence more closely matched ex vivo quantification following skin photobleaching. Three doses of blue light photobleaching (4 J/cm2, 8 J/cm2 and 12 J/cm2) were tested and determined to give similar levels of skin photobleaching as well as a similar window of decreased skin PpIX fluorescence for noninvasive fluorescence imaging following the photobleaching dose administration.

Fuel wood symposium; Symposium Energieholz

Energy Technology Data Exchange (ETDEWEB)

Wild, C.; Wauer, A. (comps.)

2001-07-01

The Bavarian State Institute of Forestry (LWF) organised a 'Fuel Wood Symposium' in Freising-Weihenstephan on 17.11.2000. The purpose of this specialist conference was to give an overview of the use of biomass, especially wood, as an source of energy. (orig.) [German] Die Bayerische Landesanstalt fuer Wald und Forstwirtschaft richtete am 17.11.2000 in Freising-Weihenstephan das 'Symposium Energieholz' aus. Ziel der Fachtagung war es, einen Ueberblick ueber die energetische Nutzung von Biomasse, insbesondere Holz, zu geben. (orig.)

6th International Symposium on Thermal Expansion

CERN Document Server

1978-01-01

This 6th International Symposium on Thermal Expansion, the first outside the USA, was held on August 29-31, 1977 at the Gull Harbour Resort on Hecla Island, Manitoba, Canada. Symposium Chairman was Ian D. Peggs, Atomic Energy of Canada Limited, and our continuing sponsor was CINDAS/Purdue University. We made considerable efforts to broaden the base this year to include more users of expansion data but with little success. We were successful, however, in establishing a session on liquids, an area which is receiving more attention as a logical extension to the high-speed thermophysical property measurements on materials at temperatures close to their melting points. The Symposium had good international representation but the overall attendance was, disappointingly, relatively low. Neverthe­ less, this enhanced the informal atmosphere throughout the meeting with a resultant frank exchange of information and ideas which all attendees appreciated. A totally new item this year was the presentation of a bursary to ...

The feasibility of using concentrates containing factor IX for continuous infusion.

Science.gov (United States)

Schulman, S; Gitel, S; Zivelin, A; Katsarou, O; Mandalaki, T; Varon, D; Martinowitz, U

1995-04-01

We have investigated the feasibility of continuous infusion of undiluted factor IX (F IX) over several days using minipumps. The stabilities of seven different reconstituted F IX products were substantially better than those declared by the manufacturers. Several concentrates maintained factor activities 80% of baseline for the entire period of 4 weeks at 4-8d̀C as did one product at 20-23d̀A. At 37d̀C the latter concentrate was stable for at least 1 week. The stability seemed to correlate with the purity of the product. Analysis of two prothrombin comples concentrates by gel electrophoresis demonstrated degradation of prothrombin to prethrombin-1 and fragment 1 at 37d̀C and in one of the concentrates also at 20-23d̀C. In two F IX concentrates the corresponding analysis did not reveal any degradation. Four patients were treated with continuous infusion with a pure F IX concentrate (Mononine™, Armour) after surgery or for serious haemorrhage (two each) with good haemostatic effect, an initial progressive decrease of the F IX clearance, and no side-effects. Continuous infusion with F IX, using a minipump and undiluted reconstituted factor, is therefore feasible and effective, and can be conveniently prepared for several days at a time. Pure F IX products are more stable and probably safer for this purpose.

Effect of PpIX photoproducts formation on pO2 measurement by time-resolved delayed fluorescence spectroscopy of PpIX in solution and in vivo.

Science.gov (United States)

Huntosova, Veronika; Gerelli, Emmanuel; Zellweger, Matthieu; Wagnières, Georges

2016-11-01

The measurement of Protoporphyrin IX delayed fluorescence lifetime is a minimally invasive method for monitoring the levels of oxygen in cells and tissues. The excitation of Protoporphyrin IX during this measurement can lead to the formation of photoproducts in vitro and in vivo. The influence of their luminescence on the measured Protoporphyrin IX delayed fluorescence lifetimes was studied in solution and in vivo on the Chick's chorioallantoic membrane (CAM) model under various oxygen enriched air conditions (0mmHg, 37mmHg and 155mmHg). The presence of photoproducts disturbs such measurements since the delayed fluorescence emission of some of them spectrally overlaps with that of Protoporphyrin IX. One possible way to avoid this obstacle is to detect Protoporphyrin IX's delayed fluorescence lifetime in a very specific spectral range (620-640nm). Another possibility is to excite Protoporphyrin IX with light doses much lower than 10J/cm 2 , quite possibly as low as a fraction 1J/cm 2 at 405nm. This leads to an increased accuracy of pO 2 detection. Furthermore, this method allows combination of diagnosis and therapy in one step. This helps to improve detection systems and real-time identification of tissue respiration, which is tuned for the detection of PpIX luminescence and not its photoproducts. Copyright © 2016 Elsevier B.V. All rights reserved.

Nuclear Structure: Dubna Symposium 1968. Invited Papers from the International Symposium on Nuclear Structure

International Nuclear Information System (INIS)

1968-01-01

Invited papers of a Symposium organized by the Joint Institute for Nuclear Research, Dubna, supported by IUPAP and IAEA, and held in Dubna from 4 to 11 July 1968. The meeting was attended by about 450 scientists from 30 countries. The volume contains the invited papers, all by distinguished scientists, and the discussions and short contributions that followed the presentation of these papers. Contents: I. Nuclear structure at low excitations (15 papers) ; II. Nuclear structure at high excitations (6 papers): III. Open problems in nuclear physics (3 papers); IV. Equilibrium deformations (6 papers); V. General properties of nuclei (6 papers); VI. Closing remarks; List of contributions; List of seminar papers; List of participants; Author index. All papers, discussions and short contributions are in English; the abstracts are in English and Russian, which were the working languages of the Symposium. (author)

Carbonic anhydrase IX (CA IX) mediates tumor cell interactions with microenvironment

Czech Academy of Sciences Publication Activity Database

Závadová, Zuzana; Závada, Jan

2005-01-01

Roč. 13, č. 5 (2005), s. 977-982 ISSN 1021-335X R&D Projects: GA ČR(CZ) GA203/02/0405 Institutional research plan: CEZ:AV0Z50520514 Keywords : carbonic anhydrase IX * cell adhesion * microenvironment Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.572, year: 2005

Factor IX gene haplotypes in Amerindians.

Science.gov (United States)

Franco, R F; Araújo, A G; Zago, M A; Guerreiro, J F; Figueiredo, M S

1997-02-01

We have determined the haplotypes of the factor IX gene for 95 Indians from 5 Brazilian Amazon tribes: Wayampí, Wayana-Apalaí, Kayapó, Arára, and Yanomámi. Eight polymorphisms linked to the factor IX gene were investigated: MseI (at 5', nt -698), BamHI (at 5', nt -561), DdeI (intron 1), BamHI (intron 2), XmnI (intron 3), TaqI (intron 4), MspI (intron 4), and HhaI (at 3', approximately 8 kb). The results of the haplotype distribution and the allele frequencies for each of the factor IX gene polymorphisms in Amerindians were similar to the results reported for Asian populations but differed from results for other ethnic groups. Only five haplotypes were identified within the entire Amerindian study population, and the haplotype distribution was significantly different among the five tribes, with one (Arára) to four (Wayampí) haplotypes being found per tribe. These findings indicate a significant heterogeneity among the Indian tribes and contrast with the homogeneous distribution of the beta-globin gene cluster haplotypes but agree with our recent findings on the distribution of alpha-globin gene cluster haplotypes and the allele frequencies for six VNTRs in the same Amerindian tribes. Our data represent the first study of factor IX-associated polymorphisms in Amerindian populations and emphasizes the applicability of these genetic markers for population and human evolution studies.

IUTAM Symposium

CERN Document Server

1995-01-01

The International Union of Theoretical and Applied Mechanics (IUTAM) decided in 1992 to sponsor the fourth Symposium on Laminar-Turbulent Transition, Sendai/Japan, 1994. The objectives of the present Symposium were to deepen the fundamental knowledge of stability and laminar­ turbulent transition in three-dimensional and compressible flows and to contribute to recent developing technologies in the field. This Symposium followed the three previous IUTAM-Symposia (Stuttgart 1979, Novosibirsk 1984 and Toulouse 1989). The Scientific Committee selected two keynote lectures and 62 technical papers. The Symposium was held on the 5th to 9th of September, 1994, at the Sendai International Center in Sendai. The participants were 82 scientists from 10 countries. The keynote lectures have critically reviewed recent development of researches concerning the laminar-to-turbulent transition phenomena from the fundamental and the application aspects. Many papers presented were concerned about the detailed mechanism of the bo...

Functional consequences of an arginine180 to glutamine mutation in factor IX Hilo.

Science.gov (United States)

Monroe, D M; McCord, D M; Huang, M N; High, K A; Lundblad, R L; Kasper, C K; Roberts, H R

1989-05-01

Factor IX Hilo is a variant factor IX molecule that has no detectable coagulant activity. The defect in factor IX Hilo arises from a point mutation in the gene such that in the protein Arg180 is converted to a Gln. Activation of factor IX Hilo by factor Xla was monitored using the fluorescent active site probe p-aminobenzamidine. Normal factor IX showed complete activation in one hour as determined by measuring the increase in fluorescence when p-aminobenzamidine bound to activated factor IX. Factor IX Hilo showed no increase in fluorescence even after 24 hours, indicating that the active site was not exposed. Polyacrylamide gel electrophoresis showed that factor IX Hilo was cleaved to a light chain plus a larger peptide with a molecular weight equivalent to a heavy chain covalently linked to an activation peptide. Amino terminal amino acid sequencing of factor IX Hilo cleaved by factor Xla showed cleavage only at Arg145-Ala146, indicating that the Gln180-Val181 bond was not cleaved and that the active site was thus not exposed. The presence of factor IX Hilo in patient plasma was responsible for the patient having a very long ox brain prothrombin time characteristic of severe hemophilia Bm. Patient plasma had an ox brain prothrombin time of 100 seconds using a Thrombotest kit, significantly prolonged over the normal control value of 45 seconds. When factor IX Hilo was depleted from patient plasma using an immunoaffinity column, the ox brain prothrombin time decreased to 41 seconds. When factor IX Hilo was added back to depleted patient plasma, to normal plasma depleted of factor IX by the same affinity column, or to plasma from a CRM- hemophilia B patient, the ox brain prothrombin time was significantly prolonged. We conclude that the Arg180 to Gln mutation in factor IX Hilo results in a molecule that cannot be activated by factor Xla. Further, our data suggest that the mutation results in a molecule that interacts with components of the extrinsic pathway to give

4p-5s transitions in YVII, VIII, ZrVIII, IX, NbIX, X and MoX, XI

International Nuclear Information System (INIS)

Rahimullah, K.; Chaghtai, M.S.Z.; Khatoon, S.

1976-01-01

The spectra of Y VII, VIII, Zr VIII, IX, Nb X and Mo X, XI are studied for the first time and the 1971 analysis of Nb IX is improved. By analyses of the transitions 4s 2 4psup(k)-4s 2 4psup(k-1)5s all the levels of the configurations 4p 3 , 4p 2 5s, 4p 2 and 4p5s are established in the spectra concerned. (Auth.)

PREFACE: Fullerene Nano Materials (Symposium of IUMRS-ICA2008)

Science.gov (United States)

Miyazawa, Kun'ichi; Fujita, Daisuke; Wakahara, Takatsugu; Kizuka, Tokushi; Matsuishi, Kiyoto; Ochiai, Yuichi; Tachibana, Masaru; Ogata, Hironori; Mashino, Tadahiko; Kumashiro, Ryotaro; Oikawa, Hidetoshi

2009-07-01

This volume contains peer-reviewed invited and contributed papers that were presented in Symposium N 'Fullerene Nano Materials' at the IUMRS International Conference in Asia 2008 (IUMRS-ICA 2008), which was held on 9-13 December 2008, at Nagoya Congress Center, Nagoya, Japan. Over twenty years have passed since the discovery of C60 in 1985. The discovery of superconductivity of C60 in 1991 suggested infinite possibilities for fullerenes. On the other hand, a new field of nanocarbon has been developed recently, based on novel functions of the low-dimensional fullerene nanomaterials that include fullerene nanowhiskers, fullerene nanotubes, fullerene nanosheets, chemically modified fullerenes, endohedral fullerenes, thin films of fullerenes and so forth. Electrical, electrochemical, optical, thermal, mechanical and various other properties of fullerene nanomaterials have been investigated and their novel and anomalous nature has been reported. Biological properties of fullerene nanomaterials also have been investigated both in medical applications and toxicity aspects. The recent research developments of fullerene nanomaterials cover a variety of categories owing to their functional diversity. This symposium aimed to review the progress in the state-of-the-art technology based on fullerenes and to offer the forum for active interdisciplinary discussions. 24 oral papers containing 8 invited papers and 22 poster papers were presented at the two-day symposium. Topics on the social acceptance of nanomaterials including fullerene were presented on the first day of the symposium. Biological impacts of nanomaterials and the importance of standardization of nanomaterials characterization were also shown. On the second day, the synthesis, properties, functions and applications of various fullerene nanomaterials were shown in both the oral and poster presentations. We are grateful to all invited speakers and many participants for valuable contributions and active discussions

X Latin American Symposium on Nuclear Physics and Applications. Book of Abstracts

International Nuclear Information System (INIS)

2013-12-01

The 10th Latin American Symposium on Nuclear Physics and Applications will be held on December 1-6, 2013 in Montevideo, Uruguay. The symposium will be preceded by a School on Medical Physics, on November 29-30, 2013. The symposium is organized by the Universidad de la Repùblica, Montevideo, by the National Superconducting Cyclotron Laboratory, Michigan, USA, and by the Thomas Jefferson National Accelerator Facility, Virginia, USA. This is the tenth event in a series which were previously held in Venezuela, Colombia, Mexico, Brazil, Argentina, Peru, Chile and Ecuador. Traditionally, the purpose of these symposia is the dissemination of major theoretical and experimental advances in nuclear science, with emphasis on research topics carried out by Latin American groups or in collaborations involving institutions from Latin America. The topics of the symposium include: Nuclear and Hadron Structure and Interactions Nuclear Reactions and Phases of Nuclear Matter Nuclear and Particle Astrophysics Tests of Fundamental Symmetries and Properties of Neutrinos Nuclear Applications New Facilities and Instrumentation.The 10th Latin American Symposium on Nuclear Physics and Applications will be held on December 1-6, 2013 in Montevideo, Uruguay. The symposium will be preceded by a School on Medical Physics, on November 29-30, 2013. The symposium is organized by the Universidad de la República, Montevideo, by the National Superconducting Cyclotron Laboratory, Michigan, USA, and by the Thomas Jefferson National Accelerator Facility, Virginia, USA. This is the tenth event in a series which were previously held in Venezuela, Colombia, Mexico, Brazil, Argentina, Peru, Chile and Ecuador. Traditionally, the purpose of these symposia is the dissemination of major theoretical and experimental advances in nuclear science, with emphasis on research topics carried out by Latin American groups or in collaborations involving institutions from Latin America. The topics of the symposium include

4th Abel Symposium

CERN Document Server

Friedlander, Eric; Jahren, Björn; Østvær, Paul

2009-01-01

The 2007 Abel Symposium took place at the University of Oslo in August 2007. The goal of the symposium was to bring together mathematicians whose research efforts have led to recent advances in algebraic geometry, algebraic K-theory, algebraic topology, and mathematical physics. A common theme of this symposium was the development of new perspectives and new constructions with a categorical flavor. As the lectures at the symposium and the papers of this volume demonstrate, these perspectives and constructions have enabled a broadening of vistas, a synergy between once-differentiated subjects, and solutions to mathematical problems both old and new.

Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells.

Science.gov (United States)

Federici, Cristina; Lugini, Luana; Marino, Maria Lucia; Carta, Fabrizio; Iessi, Elisabetta; Azzarito, Tommaso; Supuran, Claudiu T; Fais, Stefano

2016-01-01

Proton Pump Inhibitors (PPIs) reduce tumor acidity and therefore resistance of tumors to drugs. Carbonic Anhydrase IX (CA IX) inhibitors have proven to be effective against tumors, while tumor acidity might impair their full effectiveness. To analyze the effect of PPI/CA IX inhibitors combined treatment against human melanoma cells. The combination of Lansoprazole (LAN) and CA IX inhibitors (FC9-399A and S4) has been investigated in terms of cell proliferation inhibition and cell death in human melanoma cells. The combination of these inhibitors was more effective than the single treatments in both inhibiting cell proliferation and in inducing cell death in human melanoma cells. These results represent the first successful attempt in combining two different proton exchanger inhibitors. This is the first evidence on the effectiveness of a new approach against tumors based on the combination of PPI and CA IX inhibitors, thus providing an alternative strategy against tumors.

A comparative study of zinc protoporphyrin IX-forming properties of animal by-products as sources for improving the color of meat products.

Science.gov (United States)

Wakamatsu, Jun-ichi; Murakami, Naoko; Nishimura, Takanori

2015-05-01

The objective of this study was to obtain fundamental data for improving the color of meat products by using animal by-products. We investigated zinc protoporphyrin IX (ZnPP)-forming properties of various internal organs from pigs and chickens. ZnPP was formed in the liver, heart and kidney, whereas the porcine spleen and bile, which are involved in the metabolism of heme, did not have ZnPP-forming properties. The optimum pH values were different among the internal organs and the ZnPP-forming properties of porcine organs were better than those of chicken organs. The porcine liver showed the greatest ZnPP-forming properties among all of the internal organs investigated in this study. The optimum pH value for ZnPP formation in the liver was lower than that of skeletal muscle. Oxygen did not inhibit the formation of ZnPP in the liver, unlike in skeletal muscle. Animal by-products such as the liver have good ability for the formation of ZnPP and might be useful for improving the color of meat products. © 2014 Japanese Society of Animal Science.

Title IX--Beyond Compliance to Personal Commitment and Leadership

Science.gov (United States)

Peterson, Barbara

1976-01-01

In order to move beyond legal compliance to real equality of opportunity, every educational leader must develop some systematic means of extending his or her personal knowledge and skills with respect to Title IX. Provides a check list for self evaluation of educational leaders and a guide for developing an implementation plan for Title IX.…

Syntheses of carbon-13 labeled protoporphyrin-IX for spectroscopic studies of heme proteins

International Nuclear Information System (INIS)

Fujinari, E.M.

1985-01-01

The development of various methodologies for synthesis of selectively tailored protoporphyrin-IX dimethyl ester are presented. The iron(II) complex of protoporphyrin-IX is the heme, the prosthetic group for Hb, Mb, cytochromes and peroxidases. The significance of this research is to provide direct means to establish definitive carbon-13 NMR assignments of heme proteins in order to study not only the structure-function relationships, but also protein dynamics of these vital systems. Carbon-13 labeling at the beta-vinyl position was first achieved by ozonolysis of protoporphyrin-IX dimethyl ester. Column LC method were used to first isolate 2,4-diformyldeuteroporphyrin-IX dimethyl ester. Concomitantly, monofomyl-monovinyl porphyrins were obtained as a mixture of two isomers. This mixture was separated by MPLC or prep HPLC to afford the isomerically pure products, Spirographis porphyrin dimethyl ester and Iso-Spirographis porphyrin dimethyl ester. A Wittig reaction to each of these porphyrins with 13 C-methyltriphenylphosphonium iodide gave 2,4-bis[ 13 C 2 ]-vinyl protoporphyrin-IX dimethyl ester, 2-[ 13 C 2 ]-vinyl protoporphyrin-IX dimethyl ester, and the 4-[ 13 C 2 ]-vinyl protoporphyrin-IX dimethyl ester, respectively

IUTAM Symposium

CERN Document Server

Bui, Huy

1993-01-01

Inverse problems occur in a wide variey of fields. In general, the inverse problem can be defined as one where one should estimate the cause from the result, while the direct problem is concerned with how to obtain the result from the cause. The aim of this symposium was to gather scientists and researchers in engineering mechanics concerned with inverse problems in order to exchange research result and develop computational and experimentalapproaches to solve inverse problems. The contributions in this volume cover the following subjects: mathematical and computational aspects of inverse problems, parameter or system identification, shape determination, sensitivity analysis, optimization, material property characterization, ultrasonic nondestructive testing, elastodynamic inverse problems, thermal inverse problems, and other miscellaneous engineering applications.

XIII symposium. Modern chemical physics. Theses of reports

International Nuclear Information System (INIS)

2001-01-01

Materials of the thirteenth symposium on modern chemical physics are presented. They represent different directions of development of this field of knowledge, such as synthesis, structure, properties of metal-polymer compositions, radiation-chemical investigations in nanotechnology, problems of supercritical chemistry, calculations of kinetic parameters of catalytic systems [ru

Fourth Tennessee water resources symposium

International Nuclear Information System (INIS)

Sale, M.J.; Presley, P.M.

1991-01-01

The annual Tennessee Water Resources Symposium was initiated in 1988 as a means to bring together people with common interests in the state's important water-related resources at a technical, professional level. Initially the symposium was sponsored by the American Institute of Hydrology and called the Hydrology Symposium, but the Tennessee Section of the American Water Resources Association (AWRA) has taken on the primary coordination role for the symposium over the last two years and the symposium name was changed in 1990 to water resources to emphasize a more inter-disciplinary theme. This year's symposium carries on the successful tradition of the last three years. Our goal is to promote communication and cooperation among Tennessee's water resources professionals: scientists, engineers, and researchers from federal, state, academic, and private institutions and organizations who have interests and responsibilities for the state's water resources. For these conference proceedings, individual papers are processed separately for the Energy Data Base

A novel mouse PKC{delta} splice variant, PKC{delta}IX, inhibits etoposide-induced apoptosis

Energy Technology Data Exchange (ETDEWEB)

Kim, Jung D. [School of Biological Sciences, University of Ulsan, Ulsan (Korea, Republic of); Seo, Kwang W. [Department of Internal Medicines, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of); Lee, Eun A.; Quang, Nguyen N. [School of Biological Sciences, University of Ulsan, Ulsan (Korea, Republic of); Cho, Hong R. [Department of Surgery, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of); Biomedical Research Center, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of); Kwon, Byungsuk, E-mail: bskwon@mail.ulsan.as.kr [School of Biological Sciences, University of Ulsan, Ulsan (Korea, Republic of); Biomedical Research Center, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of)

2011-07-01

Highlights: {yields} A novel PKC{delta} isoform, named PKC{delta}IX, that lacks the C1 domain and the ATP-binding site is ubiquitously expressed. {yields} PKC{delta}IX inhibits etoposide-induced apoptosis. {yields} PKC{delta}IX may function as an endogenous dominant negative isoform for PKC{delta}. -- Abstract: Protein kinase C (PKC) {delta} plays an important role in cellular proliferation and apoptosis. The catalytic fragment of PKC{delta} generated by caspase-dependent cleavage is essential for the initiation of etoposide-induced apoptosis. In this study, we identified a novel mouse PKC{delta} isoform named PKC{delta}IX (Genebank Accession No. (HQ840432)). PKC{delta}IX is generated by alternative splicing and is ubiquitously expressed, as seen in its full-length PKC{delta}. PKC{delta}IX lacks the C1 domain, the caspase 3 cleavage site, and the ATP binding site but preserves an almost intact c-terminal catalytic domain and a nuclear localization signal (NLS). The structural characteristics of PKC{delta}IX provided a possibility that this PKC{delta} isozyme functions as a novel dominant-negative form for PKC{delta} due to its lack of the ATP-binding domain that is required for the kinase activity of PKC{delta}. Indeed, overexpression of PKC{delta}IX significantly inhibited etoposide-induced apoptosis in NIH3T3 cells. In addition, an in vitro kinase assay showed that recombinant PKC{delta}IX protein could competitively inhibit the kinase activity of PKC{delta}. We conclude that PKC{delta}IX can function as a natural dominant-negative inhibitor of PKC{delta}in vivo.

OPTICAL PROPERTIES OF THE ULTRALUMINOUS X-RAY SOURCE HOLMBERG IX X-1 AND ITS STELLAR ENVIRONMENT

International Nuclear Information System (INIS)

Grise, F.; Kaaret, P.; Pakull, M. W.; Motch, C.

2011-01-01

Holmberg IX X-1 is an archetypal ultraluminous X-ray source (ULX). Here we study the properties of the optical counterpart and of its stellar environment using optical data from SUBARU/Faint Object Camera and Spectrograph, GEMINI/GMOS-N and Hubble Space Telescope (HST)/Advanced Camera for Surveys, as well as simultaneous Chandra X-ray data. The V ∼ 22.6 spectroscopically identified optical counterpart is part of a loose cluster with an age ∼ sun . The counterpart is more luminous than the other stars of the association, suggesting a non-negligible optical contribution from the accretion disk. An observed UV excess also points to non-stellar light similar to X-ray active low-mass X-ray binaries. A broad He II λ4686 emission line identified in the optical spectrum of the ULX further suggests optical light from X-ray reprocessing in the accretion disk. Using stellar evolutionary tracks, we have constrained the mass of the counterpart to be ∼> 10 M sun , even if the accretion disk contributes significantly to the optical luminosity. Comparison of the photometric properties of the counterpart with binary models show that the donor may be more massive, ∼> 25 M sun , with the ULX system likely undergoing case AB mass transfer. Finally, the counterpart exhibits photometric variability of 0.14 mag between two HST observations separated by 50 days which could be due to ellipsoidal variations and/or disk reprocessing of variable X-ray emission.

Effect of IX dosing on polypropylene and PVDF membrane fouling control

KAUST Repository

Myat, Darli Theint; Mergen, Max R D; Zhao, Oliver; Stewart, Matthew B.; Orbell, John D.; Merle, Tony; Croue, Jean-Philippe; Gray, Stephen R.

2013-01-01

The performance of ion exchange (IX) resin for organics removal from wastewater was assessed using advanced characterisation techniques for varying doses of IX. Organic characterisation using liquid chromatography with a photodiode array (PDA

IX : An OS for datacenter applications with aggressive networking requirements

CERN Multimedia

CERN. Geneva

2014-01-01

The conventional wisdom is that aggressive networking requirements, such as high packet rates for small messages and microsecond-scale tail latency, are best addressed outside the kernel, in a user-level networking stack. We present IX, a dataplane operating system designed to support low-latency, high-throughput and high-connection count applications.  Like classic operating systems such as Linux, IX provides strong protection guarantees to the networking stack.  However, and unlike classic operating systems, IX is designed for the ground up to support applications with aggressive networking requirements on dense multi-core platforms with 10GbE and 40GbE Ethernet NICs.  IX outperforms Linux by an order of magnitude on micro benchmarks, and by up to 3.6x when running an unmodified memcached, a popular key-value store. The presentation is based on the joint work with Adam Belay, George Prekas, Ana Klimovic, Sam Grossman and Christos Kozyrakis, published at OSDI 2014; Best P...

COST 516 Tribology Symposium

Energy Technology Data Exchange (ETDEWEB)

Ronkainen, H.; Holmberg, K. [eds.

1998-11-01

Cost 516 Tribology action is the first joint European research action focusing on tribology, which originates in the approval of its Memorandum of understanding in February 1994. The COST 516 Tribology Symposium took place in Espoo, Finland from 14th to 15th May 1998. This was the first Symposium of the COST 516 Tribology action. The large number of research contributions at the Symposium, altogether almost SO, and their scientific and technical level, is an indication of the importance and significance of tribology research. The symposium proceedings contain papers in a wide variety of subjects, covering the three categories of the COST 516 Tribology action, namely Grease lubrication (GRIT), Tribology of renewable environmentally adapted lubricants (REAL) and Coatings and surface treatments (CAST). (orig.)

LHC Nobel Symposium Proceedings

Science.gov (United States)

Ekelöf, Tord

2013-12-01

In the summer of 2012, a great discovery emerged at the Large Hadron Collider (LHC) at CERN in Geneva. A plethora of new precision data had already by then been collected by the ATLAS and CMS experiments at LHC, providing further extensive support for the validity of the Standard Model of particle physics. But what now appeared was the first evidence for what was not only the last unverified prediction of the Standard Model, but also perhaps the most decisive one: the prediction made already in 1964 of a unique scalar boson required by the theory of François Englert and Peter Higgs on how fundamental particles acquire mass. At that moment in 2012, it seemed particularly appropriate to start planning a gathering of world experts in particle physics to take stock of the situation and try to answer the challenging question: what next? By May 2013, when the LHC Nobel Symposium was held at the Krusenberg Mansion outside Uppsala in Sweden, the first signs of a great discovery had already turned into fully convincing experimental evidence for the existence of a scalar boson of mass about 125 GeV, having properties compatible with the 50-year-old prediction. And in October 2013, the evidence was deemed so convincing that the Swedish Royal Academy of Sciences awarded the Nobel Prize in Physics to Englert and Higgs for their pioneering work. At the same time the search at the LHC for other particles, beyond those predicted by the Standard Model, with heavier masses up to—and in some cases beyond—1 TeV, had provided no positive result. The triumph of the Standard Model seems resounding, in particular because the mass of the discovered scalar boson is such that, when identified with the Higgs boson, the Standard Model is able to provide predictions at energies as high as the Planck mass, although at the price of accepting that the vacuum would be metastable. However, even if there were some feelings of triumph, the ambience at the LHC Nobel Symposium was more one of

S09 Symposium KK, Structure-Property Relationships in Biomineralized and Biomimetic Composites

Energy Technology Data Exchange (ETDEWEB)

David Kisailus; Lara Estroff; Himadri S. Gupta; William J. Landis; Pablo D. Zavattieri

2010-06-07

The technical presentations and discussions at this symposium disseminated and assessed current research and defined future directions in biomaterials research, with a focus on structure-function relationships in biological and biomimetic composites. The invited and contributed talks covered a diverse range of topics from fundamental biology, physics, chemistry, and materials science to potential applications in developing areas such as light-weight composites, multifunctional and smart materials, biomedical engineering, and nanoscaled sensors. The invited speakers were chosen to create a stimulating program with a mixture of established and junior faculty, industrial and academic researchers, and American and international experts in the field. This symposium served as an excellent introduction to the area for younger scientists (graduate students and post-doctoral researchers). Direct interactions between participants also helped to promote potential future collaborations involving multiple disciplines and institutions.

Effect of Photon Radiations in Semi-Rigid Artificial Tissue Sensitized by Protoporphyrin IX Encapsulated with Silica Nanoparticles

Science.gov (United States)

Makhadmeh, Ghaseb N.; Aziz, Azlan Abdul; Razak, Khairunisak Abdul; Al-Akhras, M.-Ali H.

2018-02-01

This study involves the synthesis of Protoporphyrin IX (PpIX) encapsulated with Silica Nanoparticles (SiNPs) as an application for Photodynamic therapy. Semi-rigid artificial tissues with optical features similar to human tissue were used as sample materials to ascertain the efficacy of PpIX encapsulated with SiNPs. The disparity in optical characteristics (transmittance, reflectance, scattering, and absorption) of tissues treated with encapsulated PpIX and naked PpIX under light exposure (Intensity at 408 nm ~1.19 mW/cm2) was explored. The optimal exposure times required for naked PpIX and SiNPs encapsulated PpIX to engulf Red Blood Cells (RBCs) in the artificial tissue were subsequently measured. Comparative analysis showed that the encapsulated PpIX has a 91.5 % higher efficacy than naked PpIX. The results prove the applicability of PpIX encapsulated with SiNP on artificial tissue and possible use on human tissue.

Electrophysiology of Cranial Nerve Testing: Cranial Nerves IX and X.

Science.gov (United States)

Martinez, Alberto R M; Martins, Melina P; Moreira, Ana Lucila; Martins, Carlos R; Kimaid, Paulo A T; França, Marcondes C

2018-01-01

The cranial nerves IX and X emerge from medulla oblongata and have motor, sensory, and parasympathetic functions. Some of these are amenable to neurophysiological assessment. It is often hard to separate the individual contribution of each nerve; in fact, some of the techniques are indeed a composite functional measure of both nerves. The main methods are the evaluation of the swallowing function (combined IX and X), laryngeal electromyogram (predominant motor vagal function), and heart rate variability (predominant parasympathetic vagal function). This review describes, therefore, the techniques that best evaluate the major symptoms presented in IX and X cranial nerve disturbance: dysphagia, dysphonia, and autonomic parasympathetic dysfunction.

Evaluation of the potential inhibitor of Ix (Pp-Ix) protoporphyrin of the genetic damage induced by gamma rays administered to different dose reasons in Drosophila melanogaster; Evaluacion del potencial inhibidor de la protoporfirina IX (PP-IX) del dano genetico inducido por rayos gama administrados a diferentes razones de dosis en Drosophila melanogaster

Energy Technology Data Exchange (ETDEWEB)

Flores A, J. A.

2016-10-01

Ionizing radiation can damage in DNA directly or indirectly by free radicals (Rl), characterized by unstable and highly reactive. To avoid damage by Rl the cell has endogenous antioxidants such as Sod, Cat, GSH or exogenous as some vitamins, but if with these mechanisms does not reach the cell homeostasis, the consequence may be the generation of chronic-disease degenerative such as cancer. This study was conducted in order to test the inhibitory role of Rl protoporphyrin Ix (Pp-Ix), induced by 20 Gy of gamma rays administered at different dose ratios using the assay of somatic mutation and recombination in the Drosophila wing. The results indicated that 20 Gy delivered at a rate of low dose (6.659 Gy/h), caused elevated frequencies of genetic damage (p <0.001), compared with those that induced a high dose reason (1111.42 Gy/h) in larvae of 48 h old. The difference is probably due to an indirect damage by Rl; when this hypothesis was approved with the possible inhibitor role of Pp-Ix (0.69 m M), damage was increased with the two reasons of tested doses. This result may be due to: 1) the Pp-Ix is not a good inhibitor of Rl, 2) the difference in the frequency of mutation found with both dose reasons, not due to Rl so that this compound did not reduce the genetic damage, and 3) that Pp-Ix acts as pro oxidant. (Author)

19.-25. IX toimub Rüütelkonna hoones Kumu pärlite nädal...

Index Scriptorium Estoniae

2005-01-01

23. IX kõneleb Anu Allikvee teemal "Eestlane baltisaksa kunstnike vaatepiiris"; 24. IX tutvustab Mai Levin Eugen Dückeri maale, 25. IX Ene Lamp Konrad Mäge. Vt. ka lk. 24 Tähtede nädal 26. IX-2. X - kohtumisõhtutel esinevad Marika ja Heinz Valk, Jüri Kuuskemaa, Sirje Helme, Pekka Vapaavuori, Inge Teder, Rain Lõhmus

Kinetics of the Factor XIa catalyzed activation of human blood coagulation Factor IX

International Nuclear Information System (INIS)

Walsh, P.N.; Bradford, H.; Sinha, D.; Piperno, J.R.; Tuszynski, G.P.

1984-01-01

The kinetics of activation of human Factor IX by human Factor XIa was studied by measuring the release of a trichloroacetic acid-soluble tritium-labeled activation peptide from Factor IX. Initial rates of trichloroacetic acid-soluble 3 H-release were linear over 10-30 min of incubation of Factor IX (88 nM) with CaCl 2 (5 mM) and with pure (greater than 98%) Factor XIa (0.06-1.3 nM), which was prepared by incubating human Factor XI with bovine Factor XIIa. Release of 3 H preceded the appearance of Factor IXa activity, and the percentage of 3 H released remained constant when the mole fraction of 3 H-labeled and unlabeled Factor IX was varied and the total Factor IX concentration remained constant. A linear correlation (r greater than 0.98, P less than 0.001) was observed between initial rates of 3 H-release and the concentration of Factor XIa, measured by chromogenic assay and by radioimmunoassay and added at a Factor IX:Factor XIa molar ratio of 70-5,600. Kinetic parameters, determined by Lineweaver-Burk analysis, include K/sub m/ (0.49 microM) of about five- to sixfold higher than the plasma Factor IX concentration, which could therefore regulate the reaction. The catalytic constant (k/sub cat/) (7.7/s) is approximately 20-50 times higher than that reported by Zur and Nemerson for Factor IX activation by Factor VIIa plus tissue factor. Therefore, depending on the relative amounts of Factor XIa and Factor VIIa generated in vivo and other factors which may influence reaction rates, these kinetic parameters provide part of the information required for assessing the relative contributions of the intrinsic and extrinsic pathways to Factor IX activation, and suggest that the Factor XIa catalyzed reaction is physiologically significant

Carnosine inhibits carbonic anhydrase IX-mediated extracellular acidosis and suppresses growth of HeLa tumor xenografts

International Nuclear Information System (INIS)

Ditte, Zuzana; Ditte, Peter; Labudova, Martina; Simko, Veronika; Iuliano, Filippo; Zatovicova, Miriam; Csaderova, Lucia; Pastorekova, Silvia; Pastorek, Jaromir

2014-01-01

Carbonic anhydrase IX (CA IX) is a transmembrane enzyme that is present in many types of solid tumors. Expression of CA IX is driven predominantly by the hypoxia-inducible factor (HIF) pathway and helps to maintain intracellular pH homeostasis under hypoxic conditions, resulting in acidification of the tumor microenvironment. Carnosine (β-alanyl-L-histidine) is an anti-tumorigenic agent that inhibits the proliferation of cancer cells. In this study, we investigated the role of CA IX in carnosine-mediated antitumor activity and whether the underlying mechanism involves transcriptional and translational modulation of HIF-1α and CA IX and/or altered CA IX function. The effect of carnosine was studied using two-dimensional cell monolayers of several cell lines with endogenous CA IX expression as well as Madin Darby canine kidney transfectants, three-dimensional HeLa spheroids, and an in vivo model of HeLa xenografts in nude mice. mRNA and protein expression and protein localization were analyzed by real-time PCR, western blot analysis, and immunofluorescence staining, respectively. Cell viability was measured by a flow cytometric assay. Expression of HIF-1α and CA IX in tumors was assessed by immunohistochemical staining. Real-time measurement of pH was performed using a sensor dish reader. Binding of CA IX to specific antibodies and metabolon partners was investigated by competitive ELISA and proximity ligation assays, respectively. Carnosine increased the expression levels of HIF-1α and HIF targets and increased the extracellular pH, suggesting an inhibitory effect on CA IX-mediated acidosis. Moreover, carnosine significantly inhibited the growth of three-dimensional spheroids and tumor xenografts compared with untreated controls. Competitive ELISA showed that carnosine disrupted binding between CA IX and antibodies specific for its catalytic domain. This finding was supported by reduced formation of the functional metabolon of CA IX and anion exchanger 2 in the

Seventh International Beaver Symposium

OpenAIRE

Yuri A. Gorshkov

2016-01-01

The paper presents data on the seventh international Beaver Symposium. Brief historical background about previous Beaver Symposia beaver is shown. Data on the sections of symposium, number of participants and reports are presented.

Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors.

Science.gov (United States)

Ditte, Peter; Dequiedt, Franck; Svastova, Eliska; Hulikova, Alzbeta; Ohradanova-Repic, Anna; Zatovicova, Miriam; Csaderova, Lucia; Kopacek, Juraj; Supuran, Claudiu T; Pastorekova, Silvia; Pastorek, Jaromir

2011-12-15

In the hypoxic regions of a tumor, carbonic anhydrase IX (CA IX) is an important transmembrane component of the pH regulatory machinery that participates in bicarbonate transport. Because tumor pH has implications for growth, invasion, and therapy, determining the basis for the contributions of CA IX to the hypoxic tumor microenvironment could lead to new fundamental and practical insights. Here, we report that Thr443 phosphorylation at the intracellular domain of CA IX by protein kinase A (PKA) is critical for its activation in hypoxic cells, with the fullest activity of CA IX also requiring dephosphorylation of Ser448. PKA is activated by cAMP, which is elevated by hypoxia, and we found that attenuating PKA in cells disrupted CA IX-mediated extracellular acidification. Moreover, following hypoxia induction, CA IX colocalized with the sodium-bicarbonate cotransporter and other PKA substrates in the leading edge membranes of migrating tumor cells, in support of the concept that bicarbonate metabolism is spatially regulated at cell surface sites with high local ion transport and pH control. Using chimeric CA IX proteins containing heterologous catalytic domains derived from related CA enzymes, we showed that CA IX activity was modulated chiefly by the intracellular domain where Thr443 is located. Our findings indicate that CA IX is a pivotal mediator of the hypoxia-cAMP-PKA axis, which regulates pH in the hypoxic tumor microenvironment.

Symposium Highlights

International Nuclear Information System (INIS)

Owen-Whitred, K.

2015-01-01

Overview/Highlights: To begin, I'd like to take a moment to highlight some of the novel elements of this Symposium as compared to those that have been held in the past. For the first time ever, this Symposium was organized around five concurrent sessions, covering over 300 papers and presentations. These sessions were complemented by an active series of exhibits put on by vendors, universities, ESARDA, INMM, and Member State Support Programmes. We also had live demonstrations throughout the week on everything from software to destructive analysis to instrumentation, which provided the participants the opportunity to see recent developments that are ready for implementation. I'm sure you all had a chance to observe - and, more importantly, interact with - the electronic Poster, or ePoster format used this past week. This technology was used here for the first time ever by the IAEA, and I'm sure was a first for many of us as well. The ePoster format allowed participants to interact with the subject matter, and the subject matter experts, in a dynamic, engaging way. In addition to the novel technology used here, I have to say that having the posters strategically embedded in the sessions on the same topic, by having each poster author introduce his or her topic to the assembled group in order to lure us to the poster area during the breaks, was also a novel and highly effective technique. A final highlight I'd like to touch on in terms of the Symposium organization is the diversity of participation. This chart shows the breakdown by geographical distribution for the Symposium, in terms of participants. There are no labels, so don't try to read any, I simply wanted to demonstrate that we had great representation in terms of both the Symposium participants in general and the session chairs more specifically-and on that note, I would just mention here that 59 Member States participated in the Symposium. But what I find especially interesting and

Effect of IX column maintenance on carbon-14 concentration in moderator systems

International Nuclear Information System (INIS)

Gallagher, C.L.; Tripple, A.W.

2006-01-01

The radionuclide 14 C is produced in CANDU reactors primarily by the (n,α) reaction with 17 O. Because of high neutron fluxes in the core, the majority of the 14 C (94.5%) is produced in the moderator. In the moderator system, 14 C is present mainly as CO 2 in the cover gas in dynamic equilibrium with dissolved carbonates, bicarbonates and CO 2 in the moderator water. Emissions of 14 C from reactors occur through venting or leakage of the cover gas. By controlling the dissolved carbonates in the moderator water with an ion exchange (IX) purification system, the amount of 14 C in the cover gas is minimized and thus the emissions of 14 C can be reduced. A study was conducted to measure the 14 C concentrations in the moderator system at Gentilly 2 in order to determine the effectiveness of the purification system in removing 14 C. Moderator water samples were obtained from the inlet and outlet of the purification system from 2004 January 14 to July 12, covering the operation of two IX columns (IX-1 and IX-3). The moderator water samples contained high levels of tritium (∼2 TBq·L -1 ). As both tritium and 14 C are β-radiation emitters, direct counting of moderator water for 14 C is impossible as the signal due to tritium dominates over that of other β-emitters. Therefore, a procedure developed by Caron et al. was used in this study, which involved acidifying the sample to release the dissolved 14 CO 2 as gas and collecting the 14 CO 2 in a base (NaOH), which could then be measured by liquid scintillation counting to determine the 14 C concentration. Both of the IX columns started with 14 C removal efficiencies of about 95%. The efficiency began to decrease almost immediately with the IX-1 column dropping to 80% efficiency after ∼1115 hours. This drop in efficiency also led to an increase in the inlet concentration over time. IX-1 column was removed from service after ∼1745 hours with a 14 C removal efficiency of ∼31%. IX-3 column was then placed in service

Seventh International Beaver Symposium

Directory of Open Access Journals (Sweden)

Yuri A. Gorshkov

2016-05-01

Full Text Available The paper presents data on the seventh international Beaver Symposium. Brief historical background about previous Beaver Symposia beaver is shown. Data on the sections of symposium, number of participants and reports are presented.

On the role of type IX collagen in the extracellular matrix of cartilage: type IX collagen is localized to intersections of collagen fibrils

OpenAIRE

1986-01-01

The tissue distribution of type II and type IX collagen in 17-d-old chicken embryo was studied by immunofluorescence using polyclonal antibodies against type II collagen and a peptic fragment of type IX collagen (HMW), respectively. Both proteins were found only in cartilage where they were co-distributed. They occurred uniformly throughout the extracellular matrix, i.e., without distinction between pericellular, territorial, and interterritorial matrices. Tissues that undergo endochondral bo...

Methods of producing protoporphyrin IX and bacterial mutants therefor

Science.gov (United States)

Zhou, Jizhong; Qiu, Dongru; He, Zhili; Xie, Ming

2016-03-01

The presently disclosed inventive concepts are directed in certain embodiments to a method of producing protoporphyrin IX by (1) cultivating a strain of Shewanella bacteria in a culture medium under conditions suitable for growth thereof, and (2) recovering the protoporphyrin IX from the culture medium. The strain of Shewanella bacteria comprises at least one mutant hemH gene which is incapable of normal expression, thereby causing an accumulation of protoporphyrin IX. In certain embodiments of the method, the strain of Shewanella bacteria is a strain of S. loihica, and more specifically may be S. loihica PV-4. In certain embodiments, the mutant hemH gene of the strain of Shewanella bacteria may be a mutant of shew_2229 and/or of shew_1140. In other embodiments, the presently disclosed inventive concepts are directed to mutant strains of Shewanella bacteria having at least one mutant hemH gene which is incapable of normal expression, thereby causing an accumulation of protoporphyrin IX during cultivation of the bacteria. In certain embodiments the strain of Shewanella bacteria is a strain of S. loihica, and more specifically may be S. loihica PV-4. In certain embodiments, the mutant hemH gene of the strain of Shewanella bacteria may be a mutant of shew_2229 and/or shew_1140.

A License for Bias: Sex Discrimination, Schools, and Title IX.

Science.gov (United States)

Morse, Susan Ed.

This report discusses non-sports-related Title IX complaints filed with the Department of Education's Office for Civil Rights (OCR) from 1993-1997. Its purpose is to dispel the popular belief that Title IX is a sports-equity law and to determine the effectiveness of the legislation. The document examines the kinds of complaints filed, the status…

The History, Uses, and Abuses of Title IX. 2016 Bulletin

Science.gov (United States)

American Association of University Professors, 2016

2016-01-01

This report, an evaluation of the history and current uses of Title IX, is the result of a joint effort by a subcommittee that included members of the AAUP's Committee A on Academic Freedom and Tenure and the Committee on Women in the Academic Profession. The report identifies tensions between current interpretations of Title IX and the academic…

Synthesis of [119mSn]-mesoporphyrin IX dichloride

International Nuclear Information System (INIS)

Denissen, J.F.

1990-01-01

Tin mesoporphyrin IX dichloride (Sn-MPCl 2 ) is a heme oxygenase inhibitor of current clinical interest for the treatment of neonatal hyperbilirubinemia. The synthesis of [ 119m Sn]-MPCl 2 for drug metabolism and disposition studies is reported. [ 119m Sn]-MPCl 2 was prepared in 60% radiochemical yield by metalation of the porphyrin nucleus of mesoporphyrin IX dihydrochloride with tin(II)-119m acetate. The product had a specific activity of 43.4 mCi/mmol and a radiochemical purity of 99%, as determined by radio-HPLC analysis. (author)

DNA Damage and Cell Cycle Arrest Induced by Protoporphyrin IX in Sarcoma 180 Cells

Directory of Open Access Journals (Sweden)

Qing Li

2013-09-01

Full Text Available Background: Porphyrin derivatives have been widely used in photodynamic therapy as effective sensitizers. Protoporphyrin IX (PpIX, a well-known hematoporphyrin derivative component, shows great potential to enhance light induced tumor cell damage. However, PpIX alone could also exert anti-tumor effects. The mechanisms underlying those direct effects are incompletely understood. This study thus investigated the putative mechanisms underlying the anti-tumor effects of PpIX on sarcoma 180 (S180 cells. Methods: S180 cells were treated with different concentrations of PpIX. Following the treatment, cell viability was evaluated by the 3-(4, 5- dimethylthiazol-2-yl-2, 5-diphenyltetrazoliumbromide (MTT assay; Disruption of mitochondrial membrane potential was measured by flow cytometry; The trans-location of apoptosis inducer factor (AIF from mitochondria to nucleus was visualized by confocal laser scanning microscopy; DNA damage was detected by single cell gel electrophoresis; Cell cycle distribution was analyzed by DNA content with flow cytometry; Cell cycle associated proteins were detected by western blotting. Results: PpIX (≥ 1 µg/ml significantly inhibited proliferation and reduced viability of S180 cells in a dose-dependent manner. PpIX rapidly and significantly triggered mitochondrial membrane depolarization, AIF (apoptosis inducer factor translocation from mitochondria to nucleus and DNA damage, effects partially relieved by the specific inhibitor of MPTP (mitochondrial permeability transition pore. Furthermore, S phase arrest and upregulation of the related proteins of P53 and P21 were observed following 12 and 24 h PpIX exposure. Conclusion: PpIX could inhibit tumor cell proliferation by induction of DNA damage and cell cycle arrest in the S phase.

Modulation of the endogenous production of protoporphyrin IX in a yeast-based model organism

Science.gov (United States)

Joniová, Jaroslava; Gerelli, Emmanuel; Wagnières, Georges

2017-02-01

The main aim of this study was to assess conditions at which simple yeast-based model organism produces maximal levels of protoporphyrin IX (PpIX) after an exogenous administration of its precursor, 5-aminolevulinic acid (ALA), and the ferrous-ion chelator 2,2'-bipyridyl. We observed that the fluorescing porphyrin, produced after these administrations, was likely to be PpIX since fluorescence spectroscopy of the porphyrins produced endogenously in yeast cells resembles that of PpIX in DMSO and in vivo in the chick's chorioallantoic membrane model. Also, fluorescence lifetimes of these porphyrins are very similar to that of PpIX in vitro and in vivo. This suggests that PpIX is the main fluorescent compound produced by yeast in our conditions. We found that the conditions at which yeast produces the maximal PpIX were a synchronous administration of 5 μM ALA and 1 mM 2,2'-bipyridyl for yeast incubated in aqueous glucose and 1 mM 2,2'-bipyridyl in the presence of YPD medium. Such a simple model is of high interest to study basic mechanisms involved in the mitochondrial respiration since PpIX, which is produced in this organelle, can be used as an oxygen sensor, or to perform photodynamic therapy and photodiagnosis. Since the absorption and scattering coefficients of this model are much smaller than those of soft tissues over the visible part of the spectrum, a version of this model loaded with appropriated amounts of light absorbing and scattering particles could be designed as a phantom to mimic tumors containing PpIX, a useful tool to optimize certain cancer photodetection set-ups.

Program and Abstracts of the ninth Joint Uzbek-Korea Symposium Nanoscience: Problems and Prospects on Quantum Functional Materials and Devices

International Nuclear Information System (INIS)

Zakhidov, E.A.; Kang, T.W.; Mamatkulov, Sh.; Kokhkharov, A.M.; Cho Hak Dong

2010-11-01

The Ninth Joint Uzbek-Korea Symposium on Quantum Functional Materials and Devices was held on November 2-5, 2010 in Tashkent, Uzbekistan. The purpose of the Symposium is to provide a forum for Uzbekistan and Korean scientists to get together and discuss recent progress and future trends in the rapidly advancing nanoscience and nanotechnology. The symposium will promote an exchange of scientific information and a mutual collaboration. Symposium activities include in-depth coverage on materials grows, physics, characterization, device fabrication and application. The main scientific topics of the symposium: Synthesis of nanomaterials, nanocomposites and nanostructures; Structural, electrical and optical properties; New concepts of devices and related phenomena; Theoretical aspects of nanosciense. (eds.)

IUTAM Symposium

CERN Document Server

Whitelaw, James; Wung, T

1992-01-01

A Symposium on Aerothermodynamics of Combustors was held at the Institute of Applied Mechanics of the National Taiwan University from 3 to 5 June 1991 and was attended by 130 delegates from eight countries. The topics of the forty formal presentations included measurements and calculations of isothermal simulations and of combusting flows with one and two phases, and with consideration of configurations ranging from simple diffusion to gas-turbine flows. The discussions inside and outside of the Symposium Hall were lively and an open forum session demonstrated the range of opinions currently and strongly held. The International Union of Theoretical and Applied Mechanics initiated the Symposium under the chairmanship of Professor R S L Lee and with the Scientific Committee listed below. It benefited from sponsorship, again as listed below, and from contributors who presented interesting and up-to-date descriptions of their research. Invited lectures were delivered by Professors R Bilger and F Weinberg and set ...

IUTAM Symposium

CERN Document Server

Shioiri, Jumpei

1996-01-01

The IUTAM Symposium on Constitutive Relation in High/Very High Strain Rates (CRHVHSR) was held October 16 - 19, 1995, at Seminar House, Science University of Tokyo, under the sponsorship of IUTAM, Japan Society for the Promotion of Science, The Commemorative Association for the Japan World Exposition (1970), Inoue Foundation for Science, The Japan Society for Aeronautical and Space Sciences, and Science University of Tokyo. The proposal to hold the symposium was accepted by the General Assembly of IUT AM held in Haifa, Israel, in August 1992, and the scientists mentioned below were appointed by the Bureau of IUTAM to serve as members of the Scientific Committee. The main object of the symposium was to make a general survey of recent developments in the research of constitutive relations in high and very high strain rates and related problems in high velocity solid mechanics, and to explore further new ideas for dealing with unresolved problems of a fundamental nature as well as of practical importance. The su...

Proceedings of the TOUGH Symposium 2009

Energy Technology Data Exchange (ETDEWEB)

Moridis, George J.; Doughty, Christine; Finsterle, Stefan; Sonnenthal, Eric

2009-10-01

Welcome to the TOUGH Symposium 2009. Within this volume are the Symposium Program for eighty-nine papers to be presented in both oral and poster formats. The full papers are available as pdfs linked from the Symposium Program posted on the TOUGH Symposium 2009 website http://esd.lbl.gov/newsandevents/events/toughsymposium09/program.html Additional updated information including any changes to the Program will also be available at the website. The papers cover a wide range of application areas and reflect the continuing trend toward increased sophistication of the TOUGH codes. A CD containing the proceedings papers will be published immediately following the Symposium and sent to all participants. As in the prior Symposium, selected papers will be invited for submission to a number of journals for inclusion in Special Issues focused on applications and developments of the TOUGH codes. These journals include, Transport in Porous Media, Geothermics, Energy Conversion and Management, Journal of Nuclear Science and Technology, and the Vadose Zone Journal.

Spectral action for Bianchi type-IX cosmological models

International Nuclear Information System (INIS)

Fan, Wentao; Fathizadeh, Farzad; Marcolli, Matilde

2015-01-01

A rationality result previously proved for Robertson-Walker metrics is extended to a homogeneous anisotropic cosmological model, namely the Bianchi type-IX minisuperspace. It is shown that the Seeley-de Witt coefficients appearing in the expansion of the spectral action for the Bianchi type-IX geometry are expressed in terms of polynomials with rational coefficients in the cosmic evolution factors w_1(t),w_2(t),w_3(t), and their higher derivates with respect to time. We begin with the computation of the Dirac operator of this geometry and calculate the coefficients a_0,a_2,a_4 of the spectral action by using heat kernel methods and parametric pseudodifferential calculus. An efficient method is devised for computing the Seeley-de Witt coefficients of a geometry by making use of Wodzicki’s noncommutative residue, and it is confirmed that the method checks out for the cosmological model studied in this article. The advantages of the new method are discussed, which combined with symmetries of the Bianchi type-IX metric, yield an elegant proof of the rationality result.

Symposium Promotes Technological Literacy through STEM

Science.gov (United States)

Havice, Bill; Marshall, Jerry

2009-01-01

This article describes a symposium which promotes technological literacy through science, technology, engineering, and mathematics (STEM). The three-day symposium titled, "The Anderson, Oconee, Pickens Symposium on Teaching and Learning STEM Standards for the 21st Century," was held August 4-6, 2008 at the Tri-County Technical College…

Bovine adenovirus type 3 containing heterologous protein in the C-terminus of minor capsid protein IX

International Nuclear Information System (INIS)

Zakhartchouk, Alexander; Connors, Wayne; Van Kessel, Andrew; Tikoo, Suresh Kumar

2004-01-01

Earlier, we detected pIX of BAdV-3 as a 14-kDa protein in purified virions. Analysis of BAdV-3 pIX using different region antibodies revealed that the N-terminus and central domain of the pIX contain immunogenic sites and are not exposed on the surface of BAdV-3 virion. This suggested that the C-terminus of BAdV-3 pIX (125 amino acid) may be exposed on the virion and may be used as a site for incorporation of heterologous peptides or proteins. We constructed recombinant BAV950 containing a small peptide (21 amino acid), including the RGD motif or recombinant BAV951 containing enhanced yellow-green fluorescent protein (EYFP) fused to the C-terminus of pIX. Western blot analysis demonstrated that the chimeric pIX-RGD was incorporated into virion capsids. Incorporation of the RGD motif into the pIX resulted in significant augmentation of BAdV-3 fiber knob-independent infection of the integrin-positive cells, suggesting that RGD motifs are displayed on the surface of virion capsids and are accessible for binding to integrins. Analysis of BAV951 revealed that the chimeric pIX is incorporated into virion capsids and EYFP containing the C-terminus of pIX is exposed on the surface of the virion. Moreover, insertion of chimeric pIXs was maintained without change through successive rounds of viral replication. These results suggested that in contrast to major capsid proteins (hexon, penton, fiber), the minor capsid protein IX can be use for the incorporation of targeting ligands based on either small peptides or longer polypeptides

Symposium report of Inter-COE international symposium on energy systems

International Nuclear Information System (INIS)

2006-10-01

The symposium of the title aims to discuss a comprehensive possibility of energy system technologies for future society utilizing both specialties of five COEs in energy technology field. The symposium topics include, 'Primary energy production', 'Energy conversion, storage and transportation', 'Energy materials', 'Energy system' by specialists from the COEs. Posters were presented by doctoral course students and others in the COEs, in addition special session 'Energy Research and Human Resources Development'. (J.P.N.)

In vitro characterization of high purity factor IX concentrates for the treatment of hemophilia B.

Science.gov (United States)

Limentani, S A; Gowell, K P; Deitcher, S R

1995-04-01

This study employed sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis and immunoblotting to assess the purity of seven high purity factor IX concentrates: Aimafix (Aima), AlphaNine-SD (Alpha Therapeutic), Factor IX VHP (Biotransfusion), Immunine (Immuno), Mononine (Armour Pharmaceutical), Nanotiv (Kabi Pharmacia), and 9MC (Blood Products Laboratory). The mean specific activity of these products ranged from 68 U factor IX/mg (Aimafix) to 246 U factor IX/mg (Mononine). SDS-PAGE analysis showed that the highest purity product, Mononine, had a single contaminating band under non-reducing conditions. Two additional bands were detected when this product was analyzed under reducing conditions. All other products had multiple contaminating bands that were more apparent under reducing than non-reducing conditions. The immunoblot for factor IX showed a dominant factor IX band for all products. In addition, visible light chain of factor IX was detected for AlphaNine-SD, Factor IX VHP, Immunine, Mononine, Nanotiv, and 9MC, suggesting that the factor IX in these products had undergone partial activation to factor IXa. Another contaminating band was visible at 49,500 for all of the products except 9MC. In addition to this band, high molecular weight contaminants were apparent for some products, most notably AlphaNine-SD. The identity of these bands is unknown. Immunoblotting failed to demonstrate factor VII as a contaminant of any of the high purity products, although factor VIIa could be detected in some lots of Immunine, Nanotiv, and 9MC by a clot-based assay. Factor X contaminated Aimafix, AlphaNine-SD, Factor IX VHP, Immunine, Nanotiv, and 9MC, but activation products of factor X were not detected.(ABSTRACT TRUNCATED AT 250 WORDS)

Influence of protoporphyrin IX loaded phloroglucinol succinic acid dendrimer in photodynamic therapy

Science.gov (United States)

Kumar, M. Suresh; Aruna, P.; Ganesan, S.

2018-03-01

One of the major problems reported clinically for photosensitizers (PS) in Photodynamic therapy (PDT) is, the cause of side-effects to normal tissue due to dark toxicity. The usefulness of photosensitizers can be made possible by reducing its dark toxicity nature. In such scenario, biocompatible carriers can be used as a drug delivery system to evade the problems that arises while using free (dark toxic) drugs. So in this study, we have developed a nano drug delivery system called Phloroglucinol Succinic acid (PGSA) dendrimer, entrapped a photosensitizer, protoporphyrin IX (PpIX) inside the system and investigated whether the photodynamic efficacy of the anionic surface charged dendrimer-PpIX nano formulation is enhanced than achieved by the free PpIX in HeLa cancer cell lines. Moreover, the Reactive oxygen species (ROS) production was monitored using 2‧,7‧-dichlorodihydrofluorescein diacetate (H2DCF-DA)- ROS Marker with phase contrast microscopy for the IC50 values of free and dendrimer-PpIX nano formulation. Similarly, the mode of cell death has been confirmed by cell cycle analysis for the same. For the in vitro PDT application, we have used a simple light source (Light Emitting Diode) with a power of 30-50 mW for 20 min irradiation. Hence, in this study we have taken steps to report this anionic drug delivery system is good to consider for the photodynamic therapy applications with the photosensitizer, PpIX which satisfied the prime requirement of PDT.

Monte Carlo modeling of in vivo protoporphyrin IX fluorescence and singlet oxygen production during photodynamic therapy for patients presenting with superficial basal cell carcinomas

Science.gov (United States)

Valentine, Ronan M.; Brown, C. Tom A.; Moseley, Harry; Ibbotson, Sally; Wood, Kenny

2011-04-01

We present protoporphyrin IX (PpIX) fluorescence measurements acquired from patients presenting with superficial basal cell carcinoma during photodynamic therapy (PDT) treatment, facilitating in vivo photobleaching to be monitored. Monte Carlo (MC) simulations, taking into account photobleaching, are performed on a three-dimensional cube grid, which represents the treatment geometry. Consequently, it is possible to determine the spatial and temporal changes to the origin of collected fluorescence and generated singlet oxygen. From our clinical results, an in vivo photobleaching dose constant, β of 5-aminolaevulinic acid-induced PpIX fluorescence is found to be 14 +/- 1 J/cm2. Results from our MC simulations suggest that an increase from our typical administered treatment light dose of 75-150 J/cm2 could increase the effective PDT treatment initially achieved at a depth of 2.7-3.3 mm in the tumor, respectively. Moreover, this increase reduces the surface PpIX fluorescence from 0.00012 to 0.000003 of the maximum value recorded before treatment. The recommendation of administrating a larger light dose, which advocates an increase in the treatment time after surface PpIX fluorescence has diminished, remains valid for different sets of optical properties and therefore should have a beneficial outcome on the total treatment effect.

Ares I-X: First Flight of a New Generation

Science.gov (United States)

Davis, Stephan R.; Askins, Bruce R.

2010-01-01

The Ares I-X suborbital development flight test demonstrated NASA s ability to design, develop, launch and control a new human-rated launch vehicle (Figure 14). This hands-on missions experience will provide the agency with necessary skills and insights regardless of the future direction of space exploration. The Ares I-X team, having executed a successful launch, will now focus on analyzing the flight data and extracting lessons learned that will be used to support the development of future vehicles.

Not Second-Class: Title IX, Equity, and Girls' High School Sports

Science.gov (United States)

Stader, David L.; Surface, Jeanne L.

2014-01-01

Title IX is designed to protect students from discrimination based on sex in any educational institution that receives financial assistance. This article focuses on Title IX as it applies to high school athletic programs by considering the trial of a high school district in California. A federal court found considerable inequalities between boys…

Evaluation of the potential inhibitor of Ix (Pp-Ix) protoporphyrin of the genetic damage induced by gamma rays administered to different dose reasons in Drosophila melanogaster

International Nuclear Information System (INIS)

Flores A, J. A.

2016-01-01

Ionizing radiation can damage in DNA directly or indirectly by free radicals (Rl), characterized by unstable and highly reactive. To avoid damage by Rl the cell has endogenous antioxidants such as Sod, Cat, GSH or exogenous as some vitamins, but if with these mechanisms does not reach the cell homeostasis, the consequence may be the generation of chronic-disease degenerative such as cancer. This study was conducted in order to test the inhibitory role of Rl protoporphyrin Ix (Pp-Ix), induced by 20 Gy of gamma rays administered at different dose ratios using the assay of somatic mutation and recombination in the Drosophila wing. The results indicated that 20 Gy delivered at a rate of low dose (6.659 Gy/h), caused elevated frequencies of genetic damage (p <0.001), compared with those that induced a high dose reason (1111.42 Gy/h) in larvae of 48 h old. The difference is probably due to an indirect damage by Rl; when this hypothesis was approved with the possible inhibitor role of Pp-Ix (0.69 m M), damage was increased with the two reasons of tested doses. This result may be due to: 1) the Pp-Ix is not a good inhibitor of Rl, 2) the difference in the frequency of mutation found with both dose reasons, not due to Rl so that this compound did not reduce the genetic damage, and 3) that Pp-Ix acts as pro oxidant. (Author)

Crispy Cracks Symposium Explores Crispness and Water Management

NARCIS (Netherlands)

Hamer, R.J.; Vliet, van T.

2008-01-01

This article provides an overview of the first international symposium on crispness creation and retention. The symposium, entitled, ¿Crispy Cracks Symposium,¿ was organized by Cereals & Europe and TI Food and Nutrition. The symposium contained three sessions: 1) Crispiness¿The Fundamentals; 2)

Embryonic chicken cornea and cartilage synthesize type IX collagen molecules with different amino-terminal domains.

OpenAIRE

Svoboda, K K; Nishimura, I; Sugrue, S P; Ninomiya, Y; Olsen, B R

1988-01-01

We have analyzed embryonic chicken cornea for the presence of type IX collagen mRNA and protein. Using RNA transfer blot analysis, we demonstrate that alpha 1(IX) and alpha 2(IX) mRNAs are expressed by corneal epithelial cells at the time that the primary stromal components are synthesized. The levels of the mRNAs decrease with increasing developmental age and are barely detectable at day 11 of development. In contrast, type IX collagen protein is detectable by immunofluorescence at days 5 an...

CONTEXT 2015 Doctorial Symposium

DEFF Research Database (Denmark)

Eklund, Peter; wegener, rebekah

2015-01-01

What is the CONTEXT 2015 Doctoral Symposium? The CONTEXT 2015 Doctoral Symposium is an opportunity for doctoral researchers to showcase their work and discuss problems, challenges, and ideas in an open and collegial environment with expert feedback. The Doctoral Symposium is a workshop for doctoral...... feedback and general advice in a constructive atmosphere. Doctoral researchers will present and discuss their research in a supportive atmosphere with other doctoral researchers and an international panel of established researchers that provide expert feedback. The workshop will take place on a single full...... day, Monday November 2, 2015, the day prior to the start of the main CONTEXT 2015 conference....

MO-FG-BRA-07: Theranostic Gadolinium-Based AGuIX Nanoparticles for MRI-Guided Radiation Therapy

International Nuclear Information System (INIS)

Detappe, A; Rottmann, J; Kunjachan, S; Berbeco, R; Tillement, O

2015-01-01

Purpose: AGuIX are gadolinium-based nanoparticles, initially developed for MRI, that have a potential role in radiation therapy as a radiosensitizer. Our goal is to demonstrate that these nanoparticles can both be used as an MRI contrast agent, as well as to obtain local dose enhancement in a pancreatic tumor when delivered in combination with an external beam irradiation. Methods: We performed in vitro cell uptake and radiosensitization studies of a pancreatic cancer cell line in a low energy (220kVp) beam, a standard clinical 6MV beam (STD) and a flattening filter free clinical 6MV beam (FFF). After injection of 40mM of nanoparticles, a biodistribution study was performed in vivo on mice with subcutaneous xenograft pancreatic tumors. In vivo radiation therapy studies were performed at the time point of maximum tumor uptake. Results: The concentration of AGuIX nanoparticles in Panc-1 pancreatic cancer cells, determined in vitro by MRI and ICPMS, peaks after 30 minutes with 0.3% of the initial concentration (5mg/g). Clonogenic assays show a significant effect (p<0.05) when the AGuIX are coupled with MV photon irradiation (DEF20%=1.31). Similar AGuIX tumor uptake is found in vivo by both MRI and ICPMS 30 minutes after intravenous injection. For long term survival studies, the choice of the radiation dose is determined with 5 control groups (3mice/group) irradiated with 0, 5, 10, 15, and 20Gy. Afterwards, 4 groups (8mice/group) are used to evaluate the effect of the nanoparticles. A Logrank test is performed as a statistical test to evaluate the effect of the nanoparticles. Conclusion: The combination of the MRI contrast and radiosensitization properties of gadolinium nanoparticles reveals a strong potential for usage with MRI-guided radiation therapy

Why, What and Where To? Title IX, Educational Amendment of 1972.

Science.gov (United States)

Perry-Miller, Mitzi

Three years after Title IX of the Education Amendments of 1972 became law, the U. S. Department of Health, Education, and Welfare provided regulations for the implementation of Title IX. This report reviews the implications of these regulations as well as several of the court cases in which discrimination on the basis of sex has been declared…

Singlet oxygen feedback delayed fluorescence of protoporphyrin IX in organic solutions.

Science.gov (United States)

Vinklárek, Ivo S; Scholz, Marek; Dědic, Roman; Hála, Jan

2017-04-12

Delayed fluorescence (DF) of protoporphyrin IX (PpIX) has been recently proposed as a tool for monitoring of mitochondrial oxygen tension in vivo as well as for observation of the effectiveness of photodynamic therapy (PDT) [E. G. Mik, Anesth. Analg., 2013, 117, 834-346; F. Piffaretti et al., J. Biomed. Opt., 2012, 17, 115007]. However, the efficiency of the mechanism of thermal activation (E-type DF), which was considered in the papers, is limited due to a large energy gap between the first excited singlet and the first triplet state of PpIX at room or body temperatures. Moreover, the energy gap is roughly equal to other porphyrinoid photosensitizers that generate DF mostly through the Singlet Oxygen Feedback-Induced mechanism (SOFDF) under certain conditions [M. Scholz and R. Dědic, Singlet Oxygen: Applications in Biosciences and Nanosciences, 2016, vol. 2, pp. 63-81]. The mechanisms of delayed fluorescence of PpIX dissolved either in dimethylformamide (DMF) or in the mixture of DMF with ethylene glycol (EG) were investigated at atmospheric partial pressure of oxygen by means of a simultaneous time-resolved detection of 1 O 2 phosphorescence and PpIX DF which makes a direct comparison of the kinetics and lifetimes of both the luminescence channels possible. Samples of PpIX (100 μM) exhibit concave DF kinetics, which is a typical footprint of the SOFDF mechanism. The dramatic decrease in the DF intensity after adding a selective 1 O 2 quencher sodium azide (NaN 3 , 10 mM) proves that >90% of DF is indeed generated through SOFDF. Moreover, the analysis of the DF kinetics in the presence of NaN 3 implies that the second significant mechanism of DF generation is the triplet-triplet annihilation (P-type DF). The bimolecular mechanism of DF was further confirmed by the decrease of the DF intensity in the more viscous mixture DMF/EG and by the increase of the ratio of DF to the prompt fluorescence (PF) intensity with the increasing excitation intensity. These results

Proceedings of the Second International Symposium on RVNRL (Radiation Vulcanisation of Natural Rubber Latex)

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-31

This book compiled the papers presented at this symposium. The papers discussed were categorized under i. preparation and properties of RVNRL, ii. characterisation and advantages of RVNRL, iii. scale up preparations and applications, iv. RVNRL pilot plant design and operation, and v. property improvement in RVNRL products,

Proceedings of the Second International Symposium on RVNRL (Radiation Vulcanisation of Natural Rubber Latex)

International Nuclear Information System (INIS)

1996-01-01

This book compiled the papers presented at this symposium. The papers discussed were categorized under i. preparation and properties of RVNRL, ii. characterisation and advantages of RVNRL, iii. scale up preparations and applications, iv. RVNRL pilot plant design and operation, and v. property improvement in RVNRL products,

Proceedings of the fifth symposium on simulation of hadronic many-body system

Energy Technology Data Exchange (ETDEWEB)

Chiba, Satoshi; Maruyama, Toshiki [eds.

1998-07-01

The fifth symposium on Simulation of Hadronic Many-Body System, organized by the Research Group for Hadron Transport Theory, Advanced Science Research Center, was held at Tokai Research Establishment of JAERI on March 3 and 4, 1998. The symposium was devoted for discussion and presentation of research results on light- and heavy-ion induced nuclear reactions in terms of microscopic simulation method, while wide variety of other topics were also presented such as nuclear structure, properties of nuclear matter and high-energy multi-fragmentation experiments. The 17 of the presented papers are indexed individually. (J.P.N.)

Spectral action for Bianchi type-IX cosmological models

Energy Technology Data Exchange (ETDEWEB)

Fan, Wentao; Fathizadeh, Farzad; Marcolli, Matilde [Division of Physics, Mathematics and Astronomy, California Institute of Technology,1200 E. California Blvd., Pasadena, CA 91125 (United States)

2015-10-13

A rationality result previously proved for Robertson-Walker metrics is extended to a homogeneous anisotropic cosmological model, namely the Bianchi type-IX minisuperspace. It is shown that the Seeley-de Witt coefficients appearing in the expansion of the spectral action for the Bianchi type-IX geometry are expressed in terms of polynomials with rational coefficients in the cosmic evolution factors w{sub 1}(t),w{sub 2}(t),w{sub 3}(t), and their higher derivates with respect to time. We begin with the computation of the Dirac operator of this geometry and calculate the coefficients a{sub 0},a{sub 2},a{sub 4} of the spectral action by using heat kernel methods and parametric pseudodifferential calculus. An efficient method is devised for computing the Seeley-de Witt coefficients of a geometry by making use of Wodzicki’s noncommutative residue, and it is confirmed that the method checks out for the cosmological model studied in this article. The advantages of the new method are discussed, which combined with symmetries of the Bianchi type-IX metric, yield an elegant proof of the rationality result.

Star formation rate in Holmberg IX dwarf galaxy

Directory of Open Access Journals (Sweden)

Anđelić M.M.

2011-01-01

Full Text Available In this paper we use previously determined Hα fluxes for dwarf galaxy Holmberg IX (Arbutina et al. 2009 to calculate star formation rate (SFR in this galaxy. We discuss possible contaminations of Hα flux and, for the first time, we take into account optical emission from supernova remnants (SNRs as a possible source of contamination of Hα flux. Derived SFR for Holmberg IX is 3:4 x 10-4M.yr-1. Our value is lower then in previous studies, due to luminous shock-heated source M&H 9-10, possible hypernova remnant, which we excluded from the total Hα flux in our calculation of SFR.

International symposium on radiative heat transfer: Book of abstracts

International Nuclear Information System (INIS)

1995-01-01

The international symposium on radiative heat transfer was held on 14-18 August 1995 Turkey. The specialists discussed radiation transfer in materials processing and manufacturing, solution of radiative heat transfer equation, transient radiation problem and radiation-turbulence interactions, raditive properties of gases, atmospheric and stellar radiative transfer , radiative transfer and its applications, optical and radiative properties of soot particles, inverse radiation problems, partticles, fibres,thermophoresis and waves and modelling of comprehensive systems at the meeting. Almost 79 papers were presented in the meeting

Prevention and Reversal of Antibody Responses Against Factor IX in Gene Therapy for Hemophilia B

Directory of Open Access Journals (Sweden)

Sushrusha eNayak

2011-12-01

Full Text Available Intramuscular (IM administration of an adeno-associated viral (AAV vector represents a simple and safe method of gene transfer for treatment of the X-linked bleeding disorder hemophilia B (factor IX, F.IX, deficiency. However, the approach is hampered by an increased risk of immune responses against F.IX. Previously, we demonstrated that the drug cocktail of immune suppressants rapamycin, IL-10, and a specific peptide (encoding a dominant CD4+ T cell epitope caused an induction of regulatory T cells (Treg with a concomitant apoptosis of antigen-specific effector T cells (J. Thromb. Haemost. 7:1523, 2009. This protocol was effective in preventing inhibitory antibody formation against human F.IX (hF.IX in muscle gene transfer to C3H/HeJ hemophilia B mice (with targeted F9 gene deletion. Here, we show that this protocol can also be used to reverse inhibitor formation. IM injection of AAV1-hF.IX vector resulted in inhibitors of on average 8-10 BU within 1 month. Subsequent treatment with the tolerogenic cocktail accomplished a rapid reduction of hF.IX-specific antibodies to <2 BU, which lasted for >4.5 months. Systemic hF.IX expression increased from undetectable to >200 ng/ml, and coagulation times improved. In addition, we developed an alternative prophylactic protocol against inhibitor formation that did not require knowledge of T cell epitopes, consisting of daily oral administration of rapamycin for 1-month combined with frequent, low-dose intravenous injection of hF.IX protein. Experiments in T cell receptor transgenic mice showed that the route and dosing schedule of drug administration substantially affected Treg induction. When combined with intravenous antigen administration, oral delivery of rapamycin had to be performed daily in order to induce Treg, which were suppressive and phenotypically comparable to natural Treg.

Protoporphyrin IX formation and photobleaching in different layers of normal human skin

DEFF Research Database (Denmark)

Togsverd-Bo, Katrine; Idorn, Luise W; Philipsen, Peter A

2012-01-01

human skin was tape-stripped and incubated with 20% methylaminolevulinate (MAL) or 20% hexylaminolevulinate (HAL) for 3 h. Fluorescence microscopy quantified PpIX accumulation in epidermis, superficial, mid and deep dermis, down to 2 mm. PpIX photobleaching by light-emitting diode (LED, 632 nm, 18......Topical photodynamic therapy (PDT) is used for various skin disorders, and selective targeting of specific skin structures is desirable. The objective was to assess accumulation of PpIX fluorescence and photobleaching within skin layers using different photosensitizers and light sources. Normal...... and 37 J/cm(2)), intense pulsed light (IPL, 500-650 nm, 36 and 72 J/cm(2)) and long-pulsed dye laser (LPDL, 595 nm, 7.5 and 15 J/cm(2)) was measured using fluorescence photography and microscopy. We found higher PpIX fluorescence intensities in epidermis and superficial dermis in HAL-incubated skin than...

A Real-Time Systems Symposium Preprint.

Science.gov (United States)

1983-09-01

Real - Time Systems Symposium Preprint Interim Tech...estimate of the occurence of the error. Unclassii ledSECUqITY CLASSIF’ICA T" NO MI*IA If’ inDI /’rrd erter for~~ble. ’Corrputnqg A REAL - TIME SYSTEMS SYMPOSIUM...ABSTRACT This technical report contains a preprint of a paper accepted for presentation at the REAL - TIME SYSTEMS SYMPOSIUM, Arlington,

International Symposium on Nuclear Safety

International Nuclear Information System (INIS)

2013-03-01

Nuclear Regulatory Authority of the Slovak Republic and the Embassy of Japan in the Slovak Republic, under the auspices of the Deputy Prime Minister and Minister of Foreign and European Affairs Mr Lajcak organized International Symposium on Nuclear Safety on 14 and 15 March 2013. The symposium took place almost exactly two years after the occurrence of accidents at the Japanese nuclear power plant Fukushima Daichi. The main mission of the symposium was an attempt to contribute to the improvement of nuclear safety by sharing information and lessons presented by Japanese experts with experts from the region, the International Atomic Energy Agency (IAEA) and the European Commission. The aim of the symposium, unlike many other events organized in connection with the events in Fukushima Daichi NPP, was a summary of the results of stress tests and measures update adopted by the international community, especially within Europe. Panel discussion was included to the program of the symposium for this aim was, mainly focused on the current state of implementation of the National Action Plan of the Slovak Republic, the Czech Republic, Poland, Ukraine and Switzerland and the IAEA Action Plan.

XX international {mu}-symposium - Brake conference. Papers; XX Internationales {mu}-Symposium - Bremsen-Fachtagung. Betraege

Energy Technology Data Exchange (ETDEWEB)

Breuer, B. [ed.] [Verein Deutscher Ingenieure (VDI), Darmstadt (Germany); Bauer, E. (comp.) [TMD Friction GmbH, Leverkusen (Germany)

2000-07-01

This year, more brake experts from the international automotive community than ever will take part in the XXth {mu}-Symposium upon the invitation of TMD Friction and learn about the latest developments in their professional fields, discuss with each other, and listen in the opening speech to the viewpoints of a behavioural scientist on braking as the main focus of {mu}-Symposium and {mu}-Club. The contents of this {mu}-Symposium will be the following: Braking from the behavioural scientist's viewpoint/research on tribological characteristics between Al-MMC brake disc and friction material/SBC - the electro-hydraulic brake system from Mercedes-Benz/total chassis management - heading for the intelligent chassis/TMD Friction - a company profile. (orig./AKF) [German] Bremsenexperten der internationalen Automobilwelt trafen sich im Herbst 2000 zum zwanzigsten Mal auf Einladung von TMD Friction in Bad Neuenahr. Dieser Bericht fasst - jeweils in deutsch und englisch - die Vortraege ueber neueste Entwicklungen aus Industrie und Hochschule zusammen. Im Einfuehrungsvortrag berichtet ein Verhaltenswissenschaftler ueber seine Gedanken zum Bremsen als dem Hauptgegenstand von {mu}-Symposium und {mu}-Club. Ferner gehoeren die Praesentation des elektrohydraulischen Bremssystems ebenso zum Programm des Symposiums wie die Vorstellung von Forschungsergebnissen neuer Reibpaarungen und der Blick auf die Zukunft des Fahrwerks im Verbund mit Fahrzeugregelsystemen. (orig./AKF)

Symposium on neutron scattering

International Nuclear Information System (INIS)

Lehmann, M.S.; Saenger, W.; Hildebrandt, G.; Dachs, H.

1984-01-01

Extended abstracts of the named symposium are presented. The first part of this report contains the abstracts of the lectures, the second those of the posters. Topics discussed on the symposium include neutron diffraction and neutron scattering studies in magnetism, solid state chemistry and physics, materials research. Some papers discussing instruments and methods are included too. (GSCH)

Evaluation of Sonochemiluminescence in a Phantom in the Presence of Protoporphyrin IX Conjugated to Nanoparticles

Directory of Open Access Journals (Sweden)

Ahmad Shanei

2012-03-01

Full Text Available Introduction When a liquid is irradiated with high-intensity and low-frequency ultrasound, acoustic cavitation occurs and there are some methods to determine and quantify this phenomenon. The existing methods for performing these experiments include sonochemiluminescence (SCL and chemical dosimetric methods. The particles in a liquid decrease the ultrasonic intensity threshold needed for cavitation onset. In this study, a new nanoconjugate made up of Protoporphyrin IX (PpIX and gold nanoparticles (GNP, i.e., Au-PpIX was used to provide nucleation sites for cavitation. The nonradiative relaxation time of PpIX in the presence of GNPs is longer than the similar time for PpIX without GNPs. This effect can be used in medical diagnostic and therapeutic applications. Materials and Methods The acoustic cavitation activity was investigated studying integrated SCL signal in the wavelength range of 400-500 nm in polyacrylamide gel phantom containing luminol using a cooled CCD spectrometer at different intensities of 1 MHz ultrasound. In order to confirm these results, a chemical dosimetric method was utilized, too. Results SCL signal level in gel phantom containing Au-PpIX was higher than the other phantoms. These results have been confirmed by the chemical dosimetric data. Conclusion This finding can be related to the existence of PpIX as a sensitizer and GNPs as cavitation nuclei. In other words, nanoparticles have acted as the sites for cavitation and have increased the cavitation rate. Another theory is that activation of PpIX has produced more free radicals and has enhanced the SCL signal level.

Pain during photodynamic therapy is associated with protoporphyrin IX fluorescence and fluence rate

DEFF Research Database (Denmark)

Wiegell, S.R.; Skiveren, J.; Philipsen, P.A.

2008-01-01

and protoporphyrin IX (PpIX) fluorescence, lesion type, lesion preparation and lesion localization. Methods Twenty-six patients with actinic keratoses (AKs) in different localizations and 34 patients with facial acne vulgaris were treated with methyl aminolaevulinate-PDT. Patients with acne were illuminated using......) patients with acne had a pain score of 6 [interquartile range (IQR) 5-7] compared with 8 (IQR 6-10) when using a fluence rate of 68 mW cm(-2) (P = 0.018). After correcting the pain score for PpIX fluorescence no differences in pain scores were found between first and second acne treatment, locations of AK...... lesions or between the two types of lesions. Conclusions Pain during PDT was correlated with the PpIX fluorescence in the treatment area prior to illumination. Pain was reduced using a lower fluence rate during PDT of acne Udgivelsesdato: 2008/4...

Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients

Czech Academy of Sciences Publication Activity Database

Závada, Jan; Závadová, Zuzana; Zaťovičová, M.; Hyršl, L.; Kawaciuk, I.

2003-01-01

Roč. 89, - (2003), s. 1067-1071 ISSN 0007-0920 R&D Projects: GA ČR GA301/99/0356 Institutional research plan: CEZ:AV0Z5052915 Keywords : carbonic anhydrase IX * tumor antigens * cancer diagnostics Subject RIV: EC - Immunology Impact factor: 3.894, year: 2003

A Place on the Team: The Triumph and Tragedy of Title IX

Science.gov (United States)

Suggs, Welch

2006-01-01

"A Place on the Team" is the inside story of how Title IX revolutionized American sports. The federal law guaranteeing women's rights in education, Title IX opened gymnasiums and playing fields to millions of young women previously locked out. Journalist Welch Suggs chronicles both the law's successes and failures-the exciting…

Abel Symposium 2015

CERN Document Server

Larsen, Nadia; Neshveyev, Sergey; Skau, Christian

2016-01-01

Like the first Abel Symposium, held in 2004, the Abel Symposium 2015 focused on operator algebras. It is interesting to see the remarkable advances that have been made in operator algebras over these years, which strikingly illustrate the vitality of the field. A total of 26 talks were given at the symposium on a variety of themes, all highlighting the richness of the subject. The field of operator algebras was created in the 1930s and was motivated by problems of quantum mechanics. It has subsequently developed well beyond its initial intended realm of applications and expanded into such diverse areas of mathematics as representation theory, dynamical systems, differential geometry, number theory and quantum algebra. One branch, known as “noncommutative geometry”, has become a powerful tool for studying phenomena that are beyond the reach of classical analysis. This volume includes research papers that present new results, surveys that discuss the development of a specific line of research, and articles ...

Validation of the protoporphyrin IX-triplet state lifetime technique for mitochondrial oxygen measurements in the skin

NARCIS (Netherlands)

F.A. Harms (Floor A.); S.I.A. Bodmer (Sander I. A.); N.J.H. Raat (Nicolaas); R.J. Stolker (Robert); E.G. Mik (Egbert)

2012-01-01

textabstractMitochondrial oxygen tension can be measured in vivo by means of oxygen-dependent quenching of delayed fluorescence of protoporphyrin IX (PpIX). Here we demonstrate that mitochondrial PO2 (mitoPO2) can be measured in the skin of a rat after topical application of the PpIX precursor

Somatic mosaicism and female-to-female transmission in a kindred with hemophilia B (factor IX deficiency)

International Nuclear Information System (INIS)

Taylor, S.A.M.; Deugau, K.V.; Lillicrap, D.P.

1991-01-01

Studies have shown that hemophilia B (Christmas disease; factor IX deficiency) results from many different mutations in the factor IX gene, of which >95% are single nulceotide substitutions. This study has identified a previously unreported form of hemophilia B in a patient who was a somatic mosaic for a guanine-to-cytosine transversion at nucleotide 31,170 in the factor IX gene. This point mutation changes the codon for residue 350 in the catalytic domain of factor IX from a cysteine to a serine. The authors used differential termination of primer extension to confirm and measure the degree of mosaicism. The study shows that a varying proportion of cells from hepatic, renal, smooth muscle, and hematopoietic populations possessed normal as well as mutant factor IX sequences. These results indicate that the mutation in this patient occurred either as an uncorrected half-chromatid mutation in the female gamete or as a replication or postreplication error in the initial mitotic divisions of the zygote preceding implantation. In addition, this kindred also contains two females in successive generations who have moderately severe factor IX deficiency. The molecular pathogenesis of this latter phenomenon has been studied and seems to relate to the unaccompanied expression of the mutant factor IX gene consequent upon a second, as yet undefined, genetic event that has prevented inactivation of sequences including the mutant factor IX gene on the X chromosome inherited from the affected male

Loop quantum cosmology of Bianchi IX: effective dynamics

International Nuclear Information System (INIS)

Corichi, Alejandro; Montoya, Edison

2017-01-01

We study solutions to the effective equations for the Bianchi IX class of spacetimes within loop quantum cosmology (LQC). We consider Bianchi IX models whose matter content is a massless scalar field, by numerically solving the loop quantum cosmology effective equations, with and without inverse triad corrections. The solutions are classified using certain geometrically motivated classical observables. We show that both effective theories—with lapse N   =   V and N   =  1—resolve the big bang singularity and reproduce the classical dynamics far from the bounce. Moreover, due to the positive spatial curvature, there is an infinite number of bounces and recollapses. We study the limit of large field momentum and show that both effective theories reproduce the same dynamics, thus recovering general relativity. We implement a procedure to identify amongst the Bianchi IX solutions, those that behave like k   =  0,1 FLRW as well as Bianchi I, II, and VII 0 models. The effective solutions exhibit Bianchi I phases with Bianchi II transitions and also Bianchi VII 0 phases, which had not been studied before. We comment on the possible implications of these results for a quantum modification to the classical BKL behaviour. (paper)

Loop quantum cosmology of Bianchi IX: effective dynamics

Science.gov (United States)

Corichi, Alejandro; Montoya, Edison

2017-03-01

We study solutions to the effective equations for the Bianchi IX class of spacetimes within loop quantum cosmology (LQC). We consider Bianchi IX models whose matter content is a massless scalar field, by numerically solving the loop quantum cosmology effective equations, with and without inverse triad corrections. The solutions are classified using certain geometrically motivated classical observables. We show that both effective theories—with lapse N  =  V and N  =  1—resolve the big bang singularity and reproduce the classical dynamics far from the bounce. Moreover, due to the positive spatial curvature, there is an infinite number of bounces and recollapses. We study the limit of large field momentum and show that both effective theories reproduce the same dynamics, thus recovering general relativity. We implement a procedure to identify amongst the Bianchi IX solutions, those that behave like k  =  0,1 FLRW as well as Bianchi I, II, and VII0 models. The effective solutions exhibit Bianchi I phases with Bianchi II transitions and also Bianchi VII0 phases, which had not been studied before. We comment on the possible implications of these results for a quantum modification to the classical BKL behaviour.

Operational Lessons Learned from the Ares I-X Flight Test

Science.gov (United States)

Davis, Stephan R.

2010-01-01

The Ares I-X flight test, launched in 2009, is the first test of the Ares I crew launch vehicle. This development flight test evaluated the flight dynamics, roll control, and separation events, but also provided early insights into logistical, stacking, launch, and recovery operations for Ares I. Operational lessons will be especially important for NASA as the agency makes the transition from the Space Shuttle to the Constellation Program, which is designed to be less labor-intensive. The mission team itself comprised only 700 individuals over the life of the project compared to the thousands involved in Shuttle and Apollo missions; while missions to and beyond low-Earth orbit obviously will require additional personnel, this lean approach will serve as a model for future Constellation missions. To prepare for Ares I-X, vehicle stacking and launch infrastructure had to be modified at Kennedy Space Center's Vehicle Assembly Building (VAB) as well as Launch Complex (LC) 39B. In the VAB, several platforms and other structures designed for the Shuttle s configuration had to be removed to accommodate the in-line, much taller Ares I-X. Vehicle preparation activities resulted in delays, but also in lessons learned for ground operations personnel, including hardware deliveries, cable routing, transferred work and custodial paperwork. Ares I-X also proved to be a resource challenge, as individuals and ground service equipment (GSE) supporting the mission also were required for Shuttle or Atlas V operations at LC 40/41 at Cape Canaveral Air Force Station. At LC 39B, several Shuttle-specific access arms were removed and others were added to accommodate the in-line Ares vehicle. Ground command, control, and communication (GC3) hardware was incorporated into the Mobile Launcher Platform (MLP). The lightning protection system at LC 39B was replaced by a trio of 600-foot-tall towers connected by a catenary wire to account for the much greater height of the vehicle. Like Shuttle

Evaluation of Sonochemiluminescence in a Phantom in the Presence of Protoporphyrin IX Conjugated to Nanoparticles

International Nuclear Information System (INIS)

Shanei, A.; Sazgarnia, A.; Hassanzadeh-Kayyat, M.; Eshghi, H.; Soudmand, S.; Attaran Kakhki, N.

2012-01-01

When a liquid is irradiated with high-intensity and low-frequency ultrasound, acoustic cavitation occurs and there are some methods to determine and quantify this phenomenon. The existing methods for performing these experiments include sonochemiluminescence and chemical dosimetric methods. The particles in a liquid decrease the ultrasonic intensity threshold needed for cavitation onset. In this study, a new nano conjugate made up of Protoporphyrin IX and gold nanoparticles, i.e., Au-PpIX was used to provide nucleation sites for cavitation. The nonradiative relaxation time of PpIX in the presence of GNPs is longer than the similar time for PpIX without GNPs. This effect can be used in medical diagnostic and therapeutic applications. The acoustic cavitation activity was investigated studying integrated sonochemiluminescence signal in the wavelength range of 400-500 nm in polyacrylamide gel phantom containing luminol using a cooled CCD spectrometer at different intensities of 1 MHz ultrasound. In order to confirm these results, a chemical dosimetric method was utilized, too. sonochemiluminescence signal level in gel phantom containing Au-PpIX was higher than the other phantoms. These results have been confirmed by the chemical dosimetric data. This finding can be related to the existence of PpIX as a sensitizer and GNPs as cavitation nuclei. In other words, nanoparticles have acted as the sites for cavitation and have increased the cavitation rate. Another theory is that activation of PpIX has produced more free radicals and has enhanced the sonochemiluminescence signal level.

International symposium on clusters and nanomaterials (energy and life-sciences applications)

Energy Technology Data Exchange (ETDEWEB)

Jena, Purusottam [Virginia Commonwealth Univ., Richmond, VA (United States)

2017-02-09

The International Symposium on Clusters and Nanomaterials was held in Richmond, Virginia during October 26-29, 2015. The symposium focused on the roles clusters and nanostructures play in solving outstanding problems in clean and sustainable energy and life sciences applications; two of the most important issues facing science and society. Many of the materials issues in renewable energies, environmental impacts of energy technologies as well as beneficial and toxicity issues of nanoparticles in health are intertwined. Realizing that both fundamental and applied materials issues require a multidisciplinary approach the symposium provided a forum by bringing researchers from physics, chemistry, materials science, and engineering fields to share their ideas and results, identify outstanding problems, and develop new collaborations. Clean and sustainable energy sessions addressed challenges in production, storage, conversion, and efficiency of renewable energies such as solar, wind, bio, thermo-electric, and hydrogen. Environmental issues dealt with air- and water-pollution and conservation, environmental remediation and hydrocarbon processing. Topics in life sciences included therapeutic and diagnostic methods as well as health hazards attributed to nanoparticles. Cross-cutting topics such as reactions, catalysis, electronic, optical, and magnetic properties were also covered. The symposium attracted 132 participants from 24 countries in the world. It featured 39 invited speakers in 14 plenary sessions, in addition to one key-note session. Eighty-five contributed papers were presented in two poster sessions and 14 papers from this list were selected to be presented orally at the end of each session to highlight hot topics. Papers presented at the symposium were reviewed and published in SPIE so that these can reach a wide audience. The symposium was highly interactive with ample time allotted for discussions and making new collaborations. The participants’ response

Increase in protoporphyrin IX after 5-aminolevulinic acid based photodynamic therapy is due to local re-synthesis

NARCIS (Netherlands)

de Bruijn, Henriëtte S.; Kruijt, Bastiaan; van der Ploeg-van den Heuvel, Angélique; Sterenborg, Henricus J. C. M.; Robinson, Dominic J.

2007-01-01

Protoporphyrin IX (PpIX) fluorescence that is bleached during aminolevulinic acid (ALA) mediated photodynamic therapy (PDT) increases again in time after treatment. In the present study we investigated if this increase in PpIX fluorescence after illumination is the result of local re-synthesis or of

189th Symposium of the International Astronomical Union

CERN Document Server

Booth, A; Davis, J

1997-01-01

This Symposium began with a proposal for a meeting to honour Emer­ itus Professor Robert Hanbury Brown on the occasion of his 80th birthday. He requested that any such meeting should be on a topic that would be of benefit to the Sydney University Stellar Interferometer (SUSI) program. With SUSI and several other high angular resolution instruments either in operation or coming on line within the next decade, and with advances in astrometry, spectroscopy and in theoretical models of stellar atmospheres and interiors, it appeared to be both appropriate and timely to hold a symposium on "Fundamental Stellar Properties: the Interaction between Observation and Theory. " The emphasis of the meeting was on the critical assessment of the qual­ ity, accuracy, and prospects for improvement of the observational data and theoretical models, on the outstanding problems in stellar astrophysics, and on the feasibility of achieving the observational and theoretical advances required for their solution. Invited papers compr...

INTRODUCTION: Physics of Low-dimensional Systems: Nobel Symposium 73

Science.gov (United States)

Lundqvist, Stig

1989-01-01

The physics of low-dimensional systems has developed in a remarkable way over the last decade and has accelerated over the last few years, in particular because of the discovery of the new high temperature superconductors. The new developments started more than fifteen years ago with the discovery of the unexpected quasi-one-dimensional character of the TTF-TCNQ. Since then the field of conducting quasi-one-dimensional organic systems have been rapidly growing. Parallel to the experimental work there has been an important theoretical development of great conceptual importance, such as charge density waves, soliton-like excitations, fractional charges, new symmetry properties etc. A new field of fundamental importance was the discovery of the Quantum Hall Effect in 1980. This field is still expanding with new experimental and theoretical discoveries. In 1986, then, came the totally unexpected discovery of high temperature superconductivity which started an explosive development. The three areas just mentioned formed the main themes of the Symposium. They do not in any way exhaust the progress in low-dimensional physics. We should mention the recent important development with both two-dimensional and one-dimensional and even zero-dimensional structures (quantum dots). The physics of mesoscopic systems is another important area where the low dimensionality is a key feature. Because of the small format of this Symposium we could unfortunately not cover these areas. A Nobel Symposium provides an excellent opportunity to bring together a group of prominent scientists for a stimulating exchange of new ideas and results. The Nobel Symposia are very small meetings by invitation only and the number of key international participants is typically in the range 25-40. These Symposia are arranged through a special Nobel Symposium Committee after proposal from individuals. This Symposium was sponsored by the Nobel Foundation through its Nobel Symposium Fund with grants from The

3. International Symposium 'Vacuum Technology and Equipment'. ISVTE-3

International Nuclear Information System (INIS)

Kogan, V.S.; Shulaev, V.M.

1999-01-01

The reports of the 3th International Symposium 'Vacuum Technology and Equipment', which was held in Kharkov at 22-24 September 1999 are presented. In this issue such subject are published: - structure and properties of thin films and coatings, and their dependencies on deposition and treatment regimes; - uses of vacuum in research and applied fields, investigation and control of vacuum systems parameters, vacuum research

Protoporphyrin IX-induced structural and functional changes in ...

Indian Academy of Sciences (India)

Unknown

Drug-protein binding; haemoglobin; myoglobin; protoporphyrin IX; red blood cells ... haemoglobin and myoglobin are potentiated by the protein-porphyrin complexation. Possible ...... 1985 Uptake and delivery of the respiratory gases; in Best ...

XV ESLAB Symposium

CERN Document Server

1981-01-01

The 15th ESLAB symposium was held at the end of June 1981 in Amsterdam with the topic being X-ray astronomy. The aim of this symposium was to bring together the international astrophysical community in order to 1. review the present state of X-ray astronomy in the light of new observations gathered in recent missions and to review data on interesting objects in correlated wavelen8th regions; 2. discuss theoretical models describing the phenomena observed; 3. present ESA's European X-ray Observatory Satellite (EXOSAT) and to discuss future X-ray missions and their associated instrumenta­ tion. These topics seemed to be so interesting for the scientific community that more than 120 contributions were submitted. Of these, 94 were finally accepted and approximately 200 participants attended the 5-day meeting. The symposium was organised in nine sessions covering the whole field. Every main topic was introduced by a review lecture covering the state­ of-the-art. The aim of the meeting was to assess the impact of...

Proceedings of the Takasaki symposium on radiation application of natural polymers in Asia

International Nuclear Information System (INIS)

Kume, Tamikazu; Maekawa, Yasunari

2002-03-01

This Takasaki symposium was annually held as the 3rd meeting for radiation processing of natural polymers through research cooperation among Asian countries. The symposium includes the presentations of research outcomes on radiation processing of starches, silk proteins and marine carbohydrates. In the researches of starch and cellulose, radiation crosslinking of biodegradable polysaccharides was achieved by modifying it to be water-soluble paste, showing the wide range of its application to wound dressing and biodegradable plastics. In silk protein researches, pulverization and water-solubilization of the irradiated silk proteins and its antibacterial properties were reported. In the researches of marine carbohydrates, it was reported that radiation-degraded chitosan and alginate showed promotion effects for plant growth, enhancement of antibacterial properties, and capability to be applied for bioadhesive materials. In addition, in estimation of economic scale of radiation application, comparisons between Japan and U.S. in medical, agricultural and industrial fields were introduced. Many domestic and foreign attendants were very interested in reports and exchanged their opinions actively. Radiation application of natural polymers are the most important subjects from the view points of resource recycling and environment protection and are good agreement with the needs of Asian countries. Outcomes of this symposium are expected to contribute the progress in radiation applications in south Asian countries as well as Japan. In the symposium we had the 63 participants consisted of 16 foreign researchers from not only bilaterally cooperated Malaysia, Thailand and Vietnam, but also Indonesia and China, 28 from domestic universities, governmental institutes and companies, and 32 from JAERI. This proceeding compiles the invited and contributed papers. The 22 of the presented papers are indexed individually. (J.P.N.)

Platelet Glycoprotein Ib-IX and Malignancy

Science.gov (United States)

2010-09-01

provide a unique microenvironment supporting the accumulation of more platelets and the elaboration of a fibrin - rich network produced by coagulation...process and can initiate the formation of a platelet - rich thrombus by tethering the platelet to a thrombogenic surface. Several ligands binding to GP Ib... Platelet Glycoprotein Ib-IX and Malignancy PRINCIPAL INVESTIGATOR: Jerry Ware, Ph.D

Eleventh symposium on energy engineering sciences: Proceedings. Solid mechanics and processing: Analysis, measurement and characterization

Energy Technology Data Exchange (ETDEWEB)

1993-09-01

The Eleventh Symposium on Energy Engineering Sciences was held on May 3--5, 1993, at the Argonne National Laboratory, Argonne, Illinois. These proceedings include the program, list of participants, and the papers that were presented during the eight technical sessions held at this meeting. This symposium was organized into eight technical sessions: Surfaces and interfaces; thermophysical properties and processes; inelastic behavior; nondestructive characterization; multiphase flow and thermal processes; optical and other measurement systems; stochastic processes; and large systems and control. Individual projects were processed separately for the databases.

Spin symposium

Energy Technology Data Exchange (ETDEWEB)

Anon.

1989-01-15

The recent 8th International Symposium on High Energy Spin Physics at the University of Minnesota in Minneapolis, Minnesota, opened with a bang when L. Pondrom (Wisconsin), donning a hard hat borrowed from construction workers, ventured that 'spin, the notorious inessential complication of hadronic physics, is finally telling us what real QCD (quantum chromodynamics, the field theory of quarks and gluons) looks like.' He was referring to an animated discussion on the meaning of the recent spin oriented (polarized) scattering results from the European Muon Collaboration (EMC) at CERN and reported at the Symposium by R. Garnet (Liverpool) and P. Schuler (Yale) which show that the proton spin is not simply a reflection of the spins of its constituent quarks.

43rd Aerospace Mechanisms Symposium

Science.gov (United States)

Boesiger, Edward A.

2016-01-01

The Aerospace Mechanisms Symposium (AMS) provides a unique forum for those active in the design, production and use of aerospace mechanisms. A major focus is the reporting of problems and solutions associated with the development and flight certification of new mechanisms. Sponsored and organized by the Mechanisms Education Association, responsibility for hosting the AMS is shared by the National Aeronautics and Space Administration and Lockheed Martin Space Systems Company (LMSSC). Now in its 43rd symposium, the AMS continues to be well attended, attracting participants from both the U.S. and abroad. The 43rd AMS was held in Santa Clara, California on May 4, 5 and 6, 2016. During these three days, 42 papers were presented. Topics included payload and positioning mechanisms, components such as hinges and motors, CubeSats, tribology, and mechanism testing. Hardware displays during the supplier exhibit gave attendees an opportunity to meet with developers of current and future mechanism components. The high quality of this symposium is a result of the work of many people, and their efforts are gratefully acknowledged. This extends to the voluntary members of the symposium organizing committee representing the eight NASA field centers, LMSSC, and the European Space Agency. Appreciation is also extended to the session chairs, the authors, and particularly the personnel at ARC responsible for the symposium arrangements and the publication of these proceedings. A sincere thank you also goes to the symposium executive committee who is responsible for the year-to-year management of the AMS, including paper processing and preparation of the program. The use of trade names of manufacturers in this publication does not constitute an official endorsement of such products or manufacturers, either expressed or implied, by the National Aeronautics and Space Administration.

Risk of Low Dose/Low Dose Rate Ionizing Radiation to Humans Symposium Annual Meeting of the Environmental Mutagen Society: Agenda and Abstracts

Energy Technology Data Exchange (ETDEWEB)

Veigl, Martina L. [Environmental Mutagen Society (EMS), Reston, VA (United States); Case Western Reserve Univ., Cleveland, OH (United States). Case Comprehensive Cancer Center; Morgan, William F. [Univ. of Maryland, College Park, MD (United States); Schwartz, Jeffrey L. [Univ. of Washington, Seattle, WA (United States)

2009-11-11

The low dose symposium thoughtfully addressed controversy of risk from low dose radiation exposure, hormesis and radon therapy. The stem cell symposium cogently considered the role of DNA damage and repair in hematopoietic stem cells underlying aging and malignancy and provocatively presented evidence that stem cells may have distinct morphologies and replicative properties, as well as special roles in cancer initiation. In the epigenetics symposium, studies illustrated the long range interaction of epigenetic mechanisms, the roles of CTCF and BORIS in region/specific regulation of epigenetic processes, the impact of DNA damage on epigenetic processes as well as links between epigenetic mechanisms and early nutrition and bystander effects. This report shows the agenda and abstracts for this symposium.

Proceedings of the symposium on networking

International Nuclear Information System (INIS)

Karita, Yukio; Abe, Fumio

1989-06-01

The first symposium on networking was held on February 6-7, 1989. Due to the increase of the needs of computer networks, several networks which connect among universities and laboratories are going to be constructed in Japan. However, the techniques in networking are not familiar to most people, and the information about these techniques is sometimes difficult to get, especially in multivendor connection. In such situation, an opportunity to hold a symposium on networking at the National Laboratory for High Energy Physics (KEK) was given. More than 200 people took part in this symposium, and the local area networks in institutions, the networks among institutions, the networks for high energy physics, the application of networks, the networks for academic research and so on are reported. The valuable discussion about networks was carried out, including the plans for near future. At the time of this symposium, the construction of the Gakujo-net and the Pacific network project of University of Hawaii were in progress, and many Japanese universities are going to construct their campus LANs, so the symposium seemed to be very timely. (K.I.)

International Symposium on Optics and its Applications (OPTICS-2011)

Science.gov (United States)

Bhattacherjee, Aranya B.; Calvo, Maria L.; Kazaryan, Eduard M.; Papoyan, Aram V.; Sarkisyan, Hayk A.

2012-03-01

OPTICS Logo PREFACE The papers selected for this volume were reported at the International Symposium 'Optics and its applications' (OPTICS-2011, Yerevan & Ashtarak, Armenia, September 5-9, 2011), http://www.ipr.sci.am/optics2011/. The Symposium was organized by the SPIE Armenian Student Chapter and major Armenian R&D organizations, universities and industrial companies working in the field of basic and applied optics: Institute for Physical Research of the National Academy of Sciences of Armenia, Yerevan State University, Russian-Armenian (Slavonic) University, and LT-PYRKAL Closed Joint Stock Company. OPTICS-2011 was primarily intended to support and promote the involvement of students and young scientists in various fields of modern optics, giving them the possibility to attend invited talks by prominent scientists and to present and discuss their own results. Furthermore, the Symposium allowed foreign participants from 14 countries to become acquainted with the achievements of optical science and technology in Armenia, which became a full member of the International Commission for Optics (ICO) in 2011. To follow this concept, the Symposium sessions were held in various host institutions. The creative and friendly ambience established at OPTICS-2011 promoted further international collaboration in the field and motivated many students to take up research in optics and photonics as a career. This volume of Journal of Physics: Conference Series covers thematic sections of the Symposium (both oral and poster), which represent the main fields of interest in optics for Armenian scientists: quantum optics & information, laser spectroscopy, optical properties of nanostructures, photonics & fiber optics, and optics of liquid crystals. Such wide coverage is consistent with the general scope of the Symposium, allowing all the students involved in optics to present, discuss and publish their recent results, and for those who are making their first steps in science to choose

Protoporphyrin IX formation after topical application of methyl aminolaevulinate and BF-200 aminolaevulinic acid declines with age

DEFF Research Database (Denmark)

Nissen, C V; Philipsen, P A; Wulf, H C

2015-01-01

BACKGROUND: Topical photodynamic therapy (PDT) is a popular treatment modality in dermatology. The effect of PDT in epidermal cells depends on formation of protoporphyrin IX (PpIX) from 5-aminolevulinic acid (ALA). A variety of physiological changes in epidermal function occur with increasing age...... assessed. Treatment efficacy in relation to age was evaluated in 100 basal cell carcinomas (BCCs) treated with MAL-PDT. RESULTS: Both photosensitizers induced significantly more PpIX formation in the younger group. Linear regression revealed a significant age-related decline in PpIX formation after...

SYMPOSIUM ON PLANT PROTEIN PHOSPHORYLATION

Energy Technology Data Exchange (ETDEWEB)

JOHN C WALKER

2011-11-01

Protein phosphorylation and dephosphorylation play key roles in many aspects of plant biology, including control of cell division, pathways of carbon and nitrogen metabolism, pattern formation, hormonal responses, and abiotic and biotic responses to environmental signals. A Symposium on Plant Protein Phosphorylation was hosted on the Columbia campus of the University of Missouri from May 26-28, 2010. The symposium provided an interdisciplinary venue at which scholars studying protein modification, as it relates to a broad range of biological questions and using a variety of plant species, presented their research. It also provided a forum where current international challenges in studies related to protein phosphorylation could be examined. The symposium also stimulated research collaborations through interactions and networking among those in the research community and engaged students and early career investigators in studying issues in plant biology from an interdisciplinary perspective. The proposed symposium, which drew 165 researchers from 13 countries and 21 States, facilitated a rapid dissemination of acquired knowledge and technical expertise regarding protein phosphorylation in plants to a broad range of plant biologists worldwide.

IUTAM Symposium on Fracture Phenomena in Nature and Technology

CERN Document Server

Carini, Angelo; Gei, Massimiliano; Salvadori, Alberto

2014-01-01

This book contains contributions presented at the IUTAM Symposium "Fracture Phenomena in Nature and Technology" held in Brescia, Italy, 1-5 July, 2012.The objective of the Symposium was fracture research, interpreted broadly to include new engineering and structural mechanics treatments of damage development and crack growth, and also large-scale failure processes as exemplified by earthquake or landslide failures, ice shelf break-up, and hydraulic fracturing (natural, or for resource extraction or CO2 sequestration), as well as small-scale rupture phenomena in materials physics including, e.g., inception of shear banding, void growth, adhesion and decohesion in contact and friction, crystal dislocation processes, and atomic/electronic scale treatment of brittle crack tips and fundamental cohesive properties.Special emphasis was given to multiscale fracture description and new scale-bridging formulations capable to substantiate recent experiments and tailored to become the basis for innovative computationa...

6th interventional MRI symposium. Abstracts

International Nuclear Information System (INIS)

2006-01-01

The ongoing progress in the field of interventional MRI and the great success of our last symposium 2004 in Boston have stimulated us to organize the 6th Interventional MRI Symposium to be held September 15-16, 2006 in Leipzig. This meeting will highlight ground-breaking research as well as cutting-edge reports from many groups. The symposium also provides a forum to network with leaders and innovators in the field. Session topics are: intraoperative MRI, vascular applications, targeted drug delivery, cryotherapy, thermometry, pulse sequences, LITT, percutaneous procedures, navigation, robotics, focused ultrasound. (uke)

PROCEEDINGS OF THE SYMPOSIUM COMMEMORATING THE 25th ANNIVERSARY OF ELEMENTS 97 and 98 HELD ON JAN. 20, 1975

Energy Technology Data Exchange (ETDEWEB)

Seaborg, Glenn T.; Street Jr., Kenneth; Thompson, Stanley G.; Ghiorso, Albert

1976-07-01

This volume includes the talks given on January 20, 1975, at a symposium in Berkeley on the occasion of the celebration of the 25th anniversary of the discovery of berkelium and californium. Talks were given at this symposium by the four people involved in the discovery of these elements and by a number of people who have made significant contributions in the intervening years to the investigation of their nuclear and chemical properties. The papers are being published here, without editing, in the form in which they were submitted by the authors in the months following the anniversary symposium, and they reflect rather faithfully the remarks made on that occasion.

Toward human organ printing: Charleston Bioprinting Symposium.

Science.gov (United States)

Mironov, Vladimir

2006-01-01

The First Annual Charleston Bioprinting Symposium was organized by the Bioprinting Research Center of the Medical University of South Carolina (MUSC) and convened July 21, 2006, in Charleston, South Carolina. In broad terms, bioprinting is the application of rapid prototyping technology to the biomedical field. More specifically, it is defined as the layer by layer deposition of biologically relevant material. The 2006 Symposium included four sessions: Computer-aided design and Bioprinting, Bioprinting Technologies; Hydrogel for Bioprinting and, finally, a special session devoted to ongoing research projects at the MUSC Bioprinting Research Center. The Symposium highlight was the presentation of the multidisciplinary Charleston Bioengineered Kidney Project. This symposium demonstrated that bioprinting or robotic biofabrication is one of the most exciting and fast-emerging branches in the tissue engineering field. Robotic biofabrication will eventually lead to industrial production of living human organs suitable for clinical transplantation. The symposium demonstrated that although there are still many technological challenges, organ printing is a rapidly evolving feasible technology.

4th International Language Management Symposium

Czech Academy of Sciences Publication Activity Database

Prošek, Martin

2016-01-01

Roč. 77, č. 3 (2016), s. 233-240 ISSN 0037-7031. [international language management symposium] Institutional support: RVO:68378092 Keywords : language management theory * international language symposium * language management Subject RIV: AI - Linguistics OBOR OECD: Linguistics Impact factor: 0.625, year: 2016

CONFERENCE NOTE: Sixth Symposium on Temperature Scheduled for March 1982

Science.gov (United States)

1981-07-01

The call for papers for the 6th Symposium on Temperature, Its Measurement and Control in Science and Industry has been issued. The Symposium is scheduled to take place in Washington, DC, USA during the week of March 14 18, 1982. Like its predecessors held in the years 1919, 1939, 1954, 1961, and 1971, the 6th Symposium will stress advances in the measurement of thermodynamic values of temperature, in temperature reference points, in temperature sensors and instruments for the control of temperature, and in the development and use of temperature scales. For the first time, an exhibit of thermometry will be a part of the Symposium. Manuscripts to be submitted for inclusion in the Symposium should be sent to the 6th Temperature Symposium Program Chairman, National Bureau of Standards, by September 15, 1981. Those papers accepted for the Symposium will be due in camera-ready form by February 15, 1982. Original papers on all of the topics listed above, as well as reviews of the past decade's progress in thermometry and temperature control, are solicited by the Symposium organizers. The Symposium arrangements and registration are in the care of the Instrument Society of America (represented on the Symposium General Committee by Mr C T Glazer, 67 Alexander Drive, PO Box 12277, Research Triangle Park, North Carolina, 27709, USA). Questions regarding the instrument exhibits should also be addressed to the ISA. The technical program for the Symposium is the responsibility of a committee headed by Dr J F Schooley, Room B-128 Physics Building, National Bureau of Standards, Washington, DC, 20234, USA. The Symposium proceedings will be published by the American Institute of Physics.

New polymorphic variants of human blood clotting factor IX

Energy Technology Data Exchange (ETDEWEB)

Surin, V.L.; Luk`yanenko, A.V.; Tagiev, A.F.; Smirnova, O.V. [Hematological Research Center, Moscow (Russian Federation); Plutalov, O.V.; Berlin, Yu.A. [Shemyakin Institute of Bioorganic Chemistry, Moscow (Russian Federation)

1995-04-01

The polymorphism of Alu-repeats, which are located in the introns of the human factor IX gene (copies 1-3), was studied. To identify polymorphic variants, direct sequencing of PCR products that contained appropriate repeats was used. In each case, 20 unrelated X chromosomes were studied. A polymorphic Dra I site was found near the 3{prime}-end of Alu copy 3 within the region of the polyA tract. A PCR-based testing system with internal control of restriction hydrolysis was suggested. Testing 81 unrelated X chromosomes revealed that the frequency of the polymorphic Dra I site is 0.23. Taq I polymorphism, which was revealed in Alu copy 4 of factor IX gene in our previous work, was found to be closely linked to Dra I polymorphism. Studies in linkage between different types of polymorphisms of the factor IX gene revealed the presence of a rare polymorphism in intron a that was located within the same minisatellite region as the known polymorphic insertion 50 bp/Dde I. However, the size of the insertion in our case was 26 bp. Only one polymorphic variant was found among over 150 unrelated X chromosomes derived from humans from Moscow and its vicinity. 10 refs., 4 figs., 1 tab.

Welcome and introduction to symposium

OpenAIRE

humanities, Symposium on Information and technology in the arts and; McLaughlin, Jeremy Lee; Matusiak, Krystyna; Hirsh, Sandra

2015-01-01

Welcome and introduction slides used for presentation at the Virtual Symposium on Information and Technology in the Arts and Humanities, held April 22 and 23, 2015. The Symposium was co-sponsored by the ASIS&T (Association for Information Science and Technology) Special Interest Group for Arts and Humanities (SIG AH) and the Special Interest Group for Visualization, Images, and Sound (SIG VIS).

Optical-sectioning microscopy of protoporphyrin IX fluorescence in human gliomas: standardization and quantitative comparison with histology

Science.gov (United States)

Wei, Linpeng; Chen, Ye; Yin, Chengbo; Borwege, Sabine; Sanai, Nader; Liu, Jonathan T. C.

2017-04-01

Systemic delivery of 5-aminolevulinic acid leads to enhanced fluorescence image contrast in many tumors due to the increased accumulation of protoporphyrin IX (PpIX), a fluorescent porphyrin that is associated with tumor burden and proliferation. The value of PpIX-guided resection of malignant gliomas has been demonstrated in prospective randomized clinical studies in which a twofold greater extent of resection and improved progression-free survival have been observed. In low-grade gliomas and at the diffuse infiltrative margins of all gliomas, PpIX fluorescence is often too weak to be detected with current low-resolution surgical microscopes that are used in operating rooms. However, it has been demonstrated that high-resolution optical-sectioning microscopes are capable of detecting the sparse and punctate accumulations of PpIX that are undetectable via conventional low-power surgical fluorescence microscopes. To standardize the performance of high-resolution optical-sectioning devices for future clinical use, we have developed an imaging phantom and methods to ensure that the imaging of PpIX-expressing brain tissues can be performed reproducibly. Ex vivo imaging studies with a dual-axis confocal microscope demonstrate that these methods enable the acquisition of images from unsectioned human brain tissues that quantitatively and consistently correlate with images of histologically processed tissue sections.

10th German nuclear law symposium

International Nuclear Information System (INIS)

Koch, H.J.; Rossnagel, A.

2000-01-01

This 10th symposium on nuclear law in Germany was held eight years after the 9th symposium. Due to the change of government after the last general elections, there had been a turnaround in Germany's energy policy. 'Phasing out nuclear energy' was the major strategy of the new Federal Government. The topics of the papers presented at the symposium therefore focus on: a new time frame for NPP shutdown and termination of operating licences; ensuring the safe operation of nuclear power plants for the remaining operating periods; new concepts for radwaste management and ultimate disposal. (orig./CB) [de

Proceedings of the seventh symposium on laser spectroscopy

International Nuclear Information System (INIS)

1999-01-01

This proceedings contains articles of the 7th symposium on laser spectroscopy and this symposium is held on Nov. 5-6, 1999 by KAERI. Both the laser and laser beams are critically used in many most precise measurements in science and technology. We discussed about the recently developed subjects in detail during the this symposium. This proceedings is composed of two major parts. One is the invitational lectures and the other is the research papers. And we have a number of invited speakers from several advanced countries. Their talks are the highlights of this symposium. (Cho, G. S.)

Proceedings of the eighth symposium on laser spectroscopy

International Nuclear Information System (INIS)

2000-01-01

This proceedings contains articles of the 8th symposium on laser spectroscopy and this symposium is held on Nov. 3-4, 2000 by KAERI. Both the laser and laser beams are critically used in many most precise measurements in science and technology. We discussed about the recently developed subjects in detail during the this symposium. This proceedings is composed of two major parts. One is the invitational lectures and the other is the research papers. And we have a number of invited speakers from several advanced countries. Their talks are the highlights of this symposium. (Yi, J. H.)

Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries

OpenAIRE

Bratslavsky, Gennady; Woodford, Mark R.; Daneshvar, Michael; Mollapour, Mehdi

2016-01-01

The Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium concluded in September 2015, in Syracuse, NY, USA. The program highlighted recent findings in a variety of areas, including drug development, therapeutics and surgical management of patients with BHD and multi-focal renal tumors, as well as multidisciplinary approaches for patients with localized, locally advanced and metastatic renal cell carcinoma.

Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries.

Science.gov (United States)

Bratslavsky, Gennady; Woodford, Mark R; Daneshvar, Michael; Mollapour, Mehdi

2016-03-29

The Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium concluded in September 2015, in Syracuse, NY, USA. The program highlighted recent findings in a variety of areas, including drug development, therapeutics and surgical management of patients with BHD and multi-focal renal tumors, as well as multidisciplinary approaches for patients with localized, locally advanced and metastatic renal cell carcinoma.

International symposium 'Energetics 2004'. Symposium proceedings. Book 1

International Nuclear Information System (INIS)

2004-01-01

The holding of this Symposium was initiated by ZEMAK - Macedonian Energy Association that for the last tens of years established itself in the national and international scientific and professional circles as a competent association of professionals with the main goal to follow, promote and improve the energy sector in the country. Having in mind the fact that the power energy sector as a fundamental sector plays a main role in the development and the improvement of the rest of the industry, and in the same time has a tremendous impact on the sustainable development of the entire economy of a country, power energy sector in fact has the paramount importance in the business environment of our country. Thus, ZEMAK has historically important role as a responsible and permanent driver, promoter and initiator for resolving of all-important questions directly or indirectly interconnected with the power energy sector in the country, and therefore the entire economy in the country as well. Following the past, ZEMAK had and would always have needs of organizing national and international symposiums and workshops as a panel where directly at one place national and international power energy experts could initiate, debate and resolve all up-to-date questions in the present energy sector in Macedonia, could analyze the modern world trends in the energy sector and try to find appropriate models for their application for further development and improvement of the energy sector in our country. This international symposium has the main goal to concentrate on a single place everybody who has power energy as a permanent preoccupation and/or vocation and professional interest. To aggregate on one place various experts, from the Academy and Universities, from the business circles and companies who are preoccupied with power energy directly or indirectly in their everyday life and work. During the Symposium more than 90 scientific and/or professional papers were presented and discussed

International symposium 'Energetics 2004'. Symposium proceedings. Book 2

International Nuclear Information System (INIS)

2004-01-01

The holding of this Symposium was initiated by ZEMAK - Macedonian Energy Association that for the last tens of years established itself in the national and international scientific and professional circles as a competent association of professionals with the main goal to follow, promote and improve the energy sector in the country. Having in mind the fact that the power energy sector as a fundamental sector plays a main role in the development and the improvement of the rest of the industry, and in the same time has a tremendous impact on the sustainable development of the entire economy of a country, power energy sector in fact has the paramount importance in the business environment of our country. Thus, ZEMAK has historically important role as a responsible and permanent driver, promoter and initiator for resolving of all-important questions directly or indirectly interconnected with the power energy sector in the country, and therefore the entire economy in the country as well. Following the past, ZEMAK had and would always have needs of organizing national and international symposiums and workshops as a panel where directly at one place national and international power energy experts could initiate, debate and resolve all up-to-date questions in the present energy sector in Macedonia, could analyze the modern world trends in the energy sector and try to find appropriate models for their application for further development and improvement of the energy sector in our country. This international symposium has the main goal to concentrate on a single place everybody who has power energy as a permanent preoccupation and/or vocation and professional interest. To aggregate on one place various experts, from the Academy and Universities, from the business circles and companies who are preoccupied with power energy directly or indirectly in their everyday life and work. During the Symposium more than 90 scientific and/or professional papers were presented and discussed

The 12th International Symposium on Spermatology

Science.gov (United States)

Aitken, R John; Cummins, Jim M; Nixon, Brett

2015-01-01

The 12th International Symposium of Spermatology continued the excellent tradition of this meeting since its inception in 1969 when the first Symposium was held in Italy under the Chairmanship of Professor Baccio Baccetti. This unique Symposium is held every 4 years and serves as a beacon for sperm cell biologists from all over the world, regardless of which species, animal or plant, they are working on. This willingness to embrace the fundamental biology of this distinctive cell type without species limitations is one of the hallmarks of this Symposium. For sperm biologists – it is our Olympics. The meeting in Newcastle, NSW brought together around 300 biologists from more than 22 different countries covering North and South America, Africa, Europe, Asia and Australia. Given the considerable distances and high cost involved in travelling to the East Coast of NSW, this was an outstanding outcome. The Symposium featured a series of 31 plenary lectures culminating in the prestigious Thaddeus Mann Memorial Lecture, which was delivered with typical grace and brilliance by Professor Masaru Okabe. PMID:25994646

Proceedings of the DAE solid state physics symposium. V. 51

International Nuclear Information System (INIS)

Bhushan, K.G.; Gupta, S.K.

2006-01-01

DAE Solid State Physics Symposium, sponsored by the Board of Research in Nuclear Sciences, Department of Atomic Energy, is organized annually. The topics covered are phase transitions, soft condensed matter, nano-materials, experimental techniques, instrumentation and solid state devices, superconductivity, magnetism, electronic structure and phonons, semiconductor physics, transport properties, surface - interface and thin films, liquids, glasses and amorphous systems, etc. Papers relevant to INIS are indexed separately

The Abel Symposium 2013

CERN Document Server

Irgens, Marius; Wold, Erlend

2015-01-01

This book focuses on complex geometry and covers highly active topics centered around geometric problems in several complex variables and complex dynamics, written by some of the world’s leading experts in their respective fields. This book features research and expository contributions from the 2013 Abel Symposium, held at the Norwegian University of Science and Technology Trondheim on July 2-5, 2013. The purpose of the symposium was to present the state of the art on the topics, and to discuss future research directions.

Memorial Symposium for Willibald Jentschke

CERN Multimedia

2002-01-01

Willibald 'Willi' Jentschke, Director General of CERN from 1971 to 1975 and founder of the DESY Laboratory in Hamburg, died last March, just a few months after celebrating his 90th birthday. At that time, the Bulletin dedicated an article to him (Bulletin n°19-20/2002). Now, CERN has organised a Memorial Symposium for next Thursday 31 October, where you are cordially invited. This tribute will include the following speechs: L. Maiani : Welcome E. Lohrmann : Message from DESY H. Schopper : Willi Jentschke M. Veltman and D. Perkins : The Neutral Currents K. Johnsen : The ISR in Jentschke's time K. Winter : Some recollections of Jentschke The Memorial Symposium will take place in the Council Chamber, Thursday 31 October at 15 hrs. Drinks will be served at 17:30 hrs following the symposium.

A Symposium.

Science.gov (United States)

Rachal, John R.

2003-01-01

Uses the framework of a symposium to present an imagined discussion by historical figures about whether and how knowledge might be acquired. Discussants include Democritus, Protagoras, Heraclitus, Socrates, Jesus, Gorgias, Nietzsche, Buddha, and Kierkegaard. (Contains 40 endnotes.) (SK)

India Symposium

Indian Academy of Sciences (India)

JNCASR

Impact of Women's research in Science and Technology in the new millennium'. The. Symposium will showcase the work done by young Indian Women Scientists in different branches of Science and Engineering, at a wide spectrum of Research ...

Use of Cre/loxP recombination to swap cell binding motifs on the adenoviral capsid protein IX

International Nuclear Information System (INIS)

Poulin, Kathy L.; Tong, Grace; Vorobyova, Olga; Pool, Madeline; Kothary, Rashmi; Parks, Robin J.

2011-01-01

We used Cre/loxP recombination to swap targeting ligands present on the adenoviral capsid protein IX (pIX). A loxP-flanked sequence encoding poly-lysine (pK-binds heparan sulfate proteoglycans) was engineered onto the 3'-terminus of pIX, and the resulting fusion protein allowed for routine virus propagation. Growth of this virus on Cre-expressing cells removed the pK coding sequence, generating virus that could only infect through alternative ligands, such as a tyrosine kinase receptor A (TrkA)-binding motif engineered into the capsid fibre protein for enhanced infection of neuronal cells. We used a similar approach to swap the pK motif on pIX for a sequence encoding a single-domain antibody directed towards CD66c for targeted infection of cancer cells; Cre-mediated removal of the pK-coding sequence simultaneously placed the single-domain antibody coding sequence in frame with pIX. Thus, we have developed a simple method to propagate virus lacking native viral tropism but containing cell-specific binding ligands. - Highlights: → We describe a method to grow virus lacking native tropism but containing novel cell-binding ligands. → Cre/loxP recombination was used to modify the adenovirus genome. → A targeting ligand present on capsid protein IX was removed or replaced using recombination. → Cre-loxP was also used to 'swap' the identity of the targeting ligand present on pIX.

1984 Statistical symposium on national energy issues: proceedings

International Nuclear Information System (INIS)

Kinnison, R.; Doctor, P.

1985-07-01

The 1984 Statistical Symposium on National Energy Issues was the tenth in a series of annual symposia bringing together statisticians and other interested parties who are actively engaged in the pursuit of solving the nation's energy problems. Initially the symposium was sponsored by US Department of Energy (DOE) and named the DOE Statistical Symposium. The symposium is organized by a steering committee made up of representatives from the national laboratories. The 1984 symposium was hosted by Pacific Northwest Laboratory, and it was organized around four special topical sessions: (1) assessing and assuring high reliability, (2) spatial statistical, (3) quantification of informed opinion, and (4) health effects of energy technologies. These were chosen by the steering committee as topics currently of high importance in energy research and data analysis. Several contributed papers were also presented. Separate abstracts have been prepared for 17 papers for inclusion in the Energy Data Base

International symposium 'Energetics 2006'. Symposium proceedings

International Nuclear Information System (INIS)

2006-01-01

ZEMAK as a civil association, created in the term positive legitimate regulations of our country, presents non party, non political and non profitable association, which primary goal is animation of eperts and other scientific and non scientific workers in the function of permanent following, studying and giving directives for solve the energy problems for a long temporal period. Behind us are fourteen successful years of fertile and wealthy work, which is bringing maimal penetration in domestic as well as foreign scientific field. This successful work of ZEMAK deserves by all members which professional work is in the institutions like: MANU (Macedonian academy of science and art), Technical faculties from the Universities, state and private company from energy field and other civil persons. The main goal of this 9-th International Symposium traditionally is to collect all engineers and eperts from the field of energy, and those which professional life is energy. During this International Symposium will be present, analyze and discuss about 100 incoming papers, prepared by 100th or more authors and coauthors, divided in the following topics: Basic energy and ecology, Renewable energy sources, Energy efficiency and energy saving and Management in energy and regulations.

Space 2000 Symposium

Science.gov (United States)

1999-01-01

The purpose of the Space 2000 Symposium is to present the creativity and achievements of key figures of the 20th century. It offers a retrospective discussion on space exploration. It considers the future of the enterprise, and the legacy that will be left for future generations. The symposium includes panel discussions, smaller session meetings with some panelists, exhibits, and displays. The first session entitled "From Science Fiction to Science Facts" commences after a brief overview of the symposium. The panel discussions include talks on space exploration over many decades, and the missions of the millennium to search for life on Mars. The second session, "Risks and Rewards of Human Space Exploration," focuses on the training and health risks that astronauts face on their exploratory mission to space. Session three, "Messages and Messengers Informing and Inspire Space Exploration and the Public," focuses on the use of TV medium by educators and actors to inform and inspire a wide variety of audiences with adventures of space exploration. Session four, "The Legacy of Carl Sagan," discusses the influences made by Sagan to scientific research and the general public. In session five, "Space Exploration for a new Generation," two student speakers and the NASA Administrator Daniel S. Goldin address the group. Session six, "Destiny or Delusion? -- Humankind's Place in the Cosmos," ends the symposium with issues of space exploration and some thought provoking questions. Some of these issues and questions are: what will be the societal implications if we discover the origin of the universe, stars, or life; what will be the impact if scientists find clear evidence of life outside the domains of the Earth; should there be limits to what humans can or should learn; and what visionary steps should space-faring people take now for future generations.

Hierarchical coassembly of DNA–triptycene hybrid molecular building blocks and zinc protoporphyrin IX

Directory of Open Access Journals (Sweden)

Rina Kumari

2016-05-01

Full Text Available Herein, we describe the successful construction of composite DNA nanostructures by the self-assembly of complementary symmetrical 2,6,14-triptycenetripropiolic acid (TPA–DNA building blocks and zinc protoporphyrin IX (Zn PpIX. DNA–organic molecule scaffolds for the composite DNA nanostructure were constructed through covalent conjugation of TPA with 5′-C12-amine-terminated modified single strand DNA (ssDNA and its complementary strand. The repeated covalent conjugation of TPA with DNA was confirmed by using denaturing polyacrylamide gel electrophoresis (PAGE, reverse-phase high-performance liquid chromatography (RP-HPLC and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF. The biologically relevant photosensitizer Zn PpIX was used to direct the hybridization-mediated self-assembly of DNA–TPA molecular building blocks as well as a model guest molecule within the DNA–TPA supramolecular self-assembly. The formation of fiber-like composite DNA nanostructures was observed. Native PAGE, circular dichroism (CD and atomic force microscopy (AFM have been utilized for analyzing the formation of DNA nanofibers after the coassembly. Computational methods were applied to discern the theoretical dimension of the DNA–TPA molecular building block of the nanofibers. A notable change in photocatalytic efficiency of Zn PpIX was observed when it was inside the TPA–DNA scaffold. The significant increase in ROS generation by Zn PpIX when trapped in this biocompatible DNA–TPA hybrid nanofiber may be an effective tool to explore photodynamic therapy (PDT applications as well as photocatalytic reactions.

PREFACE: 3rd International Symposium ''Optics and its Applications''

Science.gov (United States)

Calvo, M. L.; Dolganova, I. N.; Gevorgyan, N.; Guzman, A.; Papoyan, A.; Sarkisyan, H.; Yurchenko, S.

2016-01-01

The SPIE.FOCUS Armenia: 3rd International Symposium ''Optics and its Applications'' (OPTICS-2015) http://rau.am/optics2015/ was held in Yerevan, Armenia, in the period October 1 - 5, 2015. The symposium was organized by the International Society for Optics and Photonics (SPIE), the Armenian SPIE student chapter with collaboration of the Armenian TC of ICO, the Russian-Armenian University (RAU), the Institute for Physical Research of National Academy of Sciences of Armenia (IPR of NAS), the Greek-Armenian industrial company LT-PYRKAL, and the Yerevan State University (YSU). The Symposium was co-organized by the SPIE & OSA student chapters of BMSTU, the Armenian OSA student chapter, and the SPIE student chapters of Lund University and Wroclaw University of Technology. The symposium OPTICS-2015 was dedicated to the International Year of Light and Light-Based Technologies. OPTICS-2015 was devoted to modern topics and optical technologies such as: optical properties of nanostructures, silicon photonics, quantum optics, singular optics & its applications, laser spectroscopy, strong field optics, biomedical optics, nonlinear & ultrafast optics, photonics & fiber optics, and mathematical methods in optics. OPTICS-2015 was attended by 100 scientists and students representing 17 countries: Armenia, China, Czech Republic, France, Georgia, Germany, India, Iran, Italy, Latvia, Mexico, Poland, Russia, Saudi Arabia, Sweden, Ukraine, and USA. Such a broad international community confirmed the important mission of science to be a uniting force between different countries, religions, and nations. We hope that OPTICS-2015 inspired and motivated students and young scientists to work in optics and in science in general. The present volume of Journal of Physics: Conference Series includes proceedings of the symposium covering various aspects of modern problems in optics. We are grateful to all people who were involved in the organization process. We gratefully acknowledge support from

COMPUTING: International symposium

International Nuclear Information System (INIS)

Anon.

1984-01-01

Recent Developments in Computing, Processor, and Software Research for High Energy Physics, a four-day international symposium, was held in Guanajuato, Mexico, from 8-11 May, with 112 attendees from nine countries. The symposium was the third in a series of meetings exploring activities in leading-edge computing technology in both processor and software research and their effects on high energy physics. Topics covered included fixed-target on- and off-line reconstruction processors; lattice gauge and general theoretical processors and computing; multiprocessor projects; electron-positron collider on- and offline reconstruction processors; state-of-the-art in university computer science and industry; software research; accelerator processors; and proton-antiproton collider on and off-line reconstruction processors

Sixth international symposium on mycotoxins and phycotoxins: book of abstracts

International Nuclear Information System (INIS)

1985-01-01

This book contains only the abstracts of seminars that were delivered on the sixth international symposium on mycotoxins and phycotoxins on 22-25 July 1985 in Pretoria under the auspices of the International Union of Pure and Applied Chemistry (IUPAC) and the South African Council for Scientific and Industrial Research. Subject-coverage includes biosynthesis, metabolism, structure and chemical properties, analysis, biochemical mechanisms, toxicity, and pathology of mycotoxins and phycotoxins

Haemophilia B caused by mutation of a potential thrombin cleavage site in factor IX

Energy Technology Data Exchange (ETDEWEB)

Winship, P.R. (Univ. of Oxford (England))

1990-03-11

Haemophilia B is a blood coagulation disorder caused by mutations in the factor IX gene giving functionally defective or reduced levels of factor IX protein circulating in the plasma. The mutation in the Caucasian patient under investigation, Haemophilia B Oxford h5 (Oxh5), was characterized at the DNA level by constructing a genomic library using leucocyte-derived DNA from the patient. Overlapping recombinant clones spanning the entire factor IX locus were isolated which then allowed the generation of a series of sub-clones across all eight exons (a-h) plus the 5{prime} and 3{prime} flanking sequences known to be important in regulation of the gene and polyadenylation of the mRNA species.

6{sup th} interventional MRI symposium. Abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

The ongoing progress in the field of interventional MRI and the great success of our last symposium 2004 in Boston have stimulated us to organize the 6th Interventional MRI Symposium to be held September 15-16, 2006 in Leipzig. This meeting will highlight ground-breaking research as well as cutting-edge reports from many groups. The symposium also provides a forum to network with leaders and innovators in the field. Session topics are: intraoperative MRI, vascular applications, targeted drug delivery, cryotherapy, thermometry, pulse sequences, LITT, percutaneous procedures, navigation, robotics, focused ultrasound. (uke)

Providing Transparency to the Title IX Process

Science.gov (United States)

Hartle, Terry

2017-01-01

When U.S. Secretary of Education Betsy DeVos announced Sept. 7, 2017, that her department would revisit how Title IX rules are enforced with respect to campus sexual assault, she said the first step would be a "transparent notice and comment process" to replace the 2011 "guidance" (and follow up 2014 guidance) that has been…

The fifth Finnish national aerosol symposium

International Nuclear Information System (INIS)

Mikkanen, P.; Haemeri, K.; Kauppinen, E.

1993-01-01

The Fifth Finnish Aerosol Symposium was held June 1-3, 1993. Symposium is jointly organized by FAAR, Aerosol Technology Group of Technical Research Centre of Finland and Helsinki University, Department of Physics. Aerosols, the suspensions of solid and liquid particles and gases, are receiving increasing importance in many areas of science and technology. These include industrial hygiene, ambient and indoor air pollution, pollution control technologies, cloud physics, nuclear safety engineering, combustion science and engineering, clean manufacturing technologies and material processing. The importance of aerosol issues during the development of advanced fuel conversion and material processing technologies can be realized when looking at the numerous papers presented on these topics at the Symposium

IUTAM Symposium

CERN Document Server

Stefanou, George

2014-01-01

This book contains the proceedings of the IUTAM Symposium on Multiscale Modeling and Uncertainty Quantification of Materials and Structures that was held at Santorini, Greece, September 9 – 11, 2013. It consists of 20 chapters which are divided in five thematic topics: Damage and fracture, homogenization, inverse problems–identification, multiscale stochastic mechanics and stochastic dynamics. Over the last few years, the intense research activity at microscale and nanoscale reflected the need to account for disparate levels of uncertainty from various sources and across scales. As even over-refined deterministic approaches are not able to account for this issue, an efficient blending of stochastic and multiscale methodologies is required to provide a rational framework for the analysis and design of materials and structures. The purpose of this IUTAM Symposium was to promote achievements in uncertainty quantification combined with multiscale modeling and to encourage research and development in this grow...

The 20th Hadron Collider Physics Symposium in Evian

CERN Multimedia

Ludwik Dobrzynski and Emmanuel Tsesmelis

The 20th Hadron Collider Physics Symposium took place in Evian from 16 to 20 November 2009. The Hadron Collider Physics Symposium series has been a major forum for presentations of physics at the Tevatron over the past two decades. The merger of the former Topical Conference on Hadron Collider Physics with the LHC Symposium in 2005 brought together the Tevatron and LHC communities in a single forum. The 20th Hadron Collider Physics Symposium took place in Evian, on the shores of Lake Geneva, from 16-20 November 2009, some 17 years after the historic ECFA-CERN Evian meeting in March 1992 when Expressions of Interest for LHC detectors were presented for the first time. The 2009 event was organized jointly by CERN and the French high-energy physics community (CNRS-IN2P3 and CEA-IRFU). More than 170 people registered for this symposium. This year’s symposium was held at an important time for both the Tevatron and the LHC. It stimulated the completion of analyses for a significant Tevatron data sam...

Coal economics and taxation discussed at symposium

Energy Technology Data Exchange (ETDEWEB)

1978-06-01

Some of the highlights from the Symposium on Coal Economics and Taxation Symposium, Regina Saskatchewan May 7-9, 1978, sponsored by the Coal Association of Canada are presented. Investment, provincial policy, sources of funds, uncertainty, tax policies, and operating costs are discussed.

Symposium on unsaturated flow and transport modeling

International Nuclear Information System (INIS)

Arnold, E.M.; Gee, G.W.; Nelson, R.W.

1982-09-01

This document records the proceedings of a symposium on flow and transport processes in partially saturated groundwater systems, conducted at the Battelle Seattle Research Center on March 22-24, 1982. The symposium was sponsored by the US Nuclear Regulatory Commission for the purpose of assessing the state-of-the-art of flow and transport modeling for use in licensing low-level nuclear waste repositories in partially saturated zones. The first day of the symposium centered around research in flow through partially saturated systems. Papers were presented with the opportunity for questions following each presentation. In addition, after all the talks, a formal panel discussion was held during which written questions were addressed to the panel of the days speakers. The second day of the Symposium was devoted to solute and contaminant transport in partially saturated media in an identical format. Individual papers are abstracted

Symposium on unsaturated flow and transport modeling

Energy Technology Data Exchange (ETDEWEB)

Arnold, E.M.; Gee, G.W.; Nelson, R.W. (eds.)

1982-09-01

This document records the proceedings of a symposium on flow and transport processes in partially saturated groundwater systems, conducted at the Battelle Seattle Research Center on March 22-24, 1982. The symposium was sponsored by the US Nuclear Regulatory Commission for the purpose of assessing the state-of-the-art of flow and transport modeling for use in licensing low-level nuclear waste repositories in partially saturated zones. The first day of the symposium centered around research in flow through partially saturated systems. Papers were presented with the opportunity for questions following each presentation. In addition, after all the talks, a formal panel discussion was held during which written questions were addressed to the panel of the days speakers. The second day of the Symposium was devoted to solute and contaminant transport in partially saturated media in an identical format. Individual papers are abstracted.

Increased protoporphyrin IX accumulation does not improve the effect of photodynamic therapy for actinic keratosis

DEFF Research Database (Denmark)

Nissen, C V; Heerfordt, I M; Wiegell, S R

2017-01-01

BACKGROUND: Photodynamic therapy (PDT) with methyl aminolaevulinate (MAL) is highly effective for treating actinic keratosis (AK) on the face/scalp, but less effective on the extremities. Insufficient accumulation of protoporphyrin IX (PpIX) may cause these inferior efficacy rates. However...... (P = 0·001 and P = 0·002, respectively). However, the median total clearance rates did not improve accordingly: 3hC+ (55·0%), 21hC- (55·0%) and 21hC+ (53·6%). Conversely, insufficient PpIX accumulation in the 3hC- regimen led to a significantly lower clearance rate (33·3%) than the other regimens (P...

IAEA symposium on international safeguards

International Nuclear Information System (INIS)

1999-01-01

The eighth IAEA Symposium on International Safeguards was organized by the IAEA in cooperation with the Institute of Nuclear Materials Management and the European Safeguards Research and Development Association. It was attended by over 350 specialists and policy makers in the field of nuclear safeguards and verification from more than 50 countries and organizations. The purpose of the Symposium was to foster a broad exchange of information on concepts and technologies related to important developments in the areas of international safeguards and security. For the first time in the history of the symposia, the IAEA is issuing proceedings free of charge to participants on CD-ROM. The twenty-two plenary, technical, and poster sessions featured topics related to technological and policy aspects from national, regional and global perspectives. The theme of the Symposium: Four Decades of Development - Safeguarding into the New Millennium set the stage for the commemoration of a number of significant events in the annals of safeguards. 1997 marked the Fortieth Anniversary of the IAEA, the Thirtieth Anniversary of the Tlatelolco Treaty, and the Twentieth Anniversary of the Department of Safeguards Member State Support Programmes. There were special events and noted presentations featuring these anniversaries and giving the participants an informative retrospective view of safeguards development over the past four decades. The proceedings of this symposium provide the international community with a comprehensive view of where nuclear safeguards and verification stood in 1997 in terms of the growing demands and expectations. The Symposium offered thoughtful perspectives on where safeguards are headed within the broader context of verification issues. As the world of international nuclear verification looks towards the next millennium, the implementation of the expanding and strengthened safeguards system presents formidable challenges

Proceedings of the sixth symposium on laser spectroscopy

International Nuclear Information System (INIS)

1998-11-01

This proceedings contains articles of the 6th symposium on laser spectroscopy and this symposium is held on Nov. 3-4, 1998 by KAERI. Laser spectroscopy is one of the most important areas in optical science and engineering and we discussed about the recently developed subjects in detail during the this symposium. This proceedings is composed of two major parts. One is the invitational lectures and the other is the research papers. This have a very important and very valuable lecture by Dr. William Phillips who is the 1997 Nobel Laureate in Physics. His special lecture was very wonderful and fruitful. And we have a number of invited speakers from several advanced countries. Their talks are the highlights of this symposium. (Cho, G. S.)

Legal Forum: Title IX: Does It Apply to Employees?

Science.gov (United States)

McCarthy, Martha

1981-01-01

Briefly reviews a number of Federal court cases that have dealt with Title IX, considering the issue of whether the 1974 regulations prohibiting sex discrimination in employment practices accurately reflect the intent of the 1972 law. (GC)

In vivo wide-field multispectral dosimeter for use in ALA-PpIX based photodynamic therapy of skin

Science.gov (United States)

LaRochelle, Ethan P. M.; Davis, Scott C.; de Souza, Ana Luiza Ribeiro; Pogue, Brian W.

2017-02-01

Photodynamic therapy (PDT) for Actinic Kertoses (AK) using aminoluvelinic acid (ALA) is an FDA-approved treatment, which is generally effective, yet response rates vary. The origin of the variability is not well characterized, but may be related to inter-patient variability in the production of protoporphyrin IX (PpIX). While fiber-based point probe systems provide a method for measuring PpIX production, these measurements have demonstrated large spatial and inter-operator variability. Thus, in an effort to improve patient-specific dosimetry and treatment it is important to develop a robust system that accounts for spatial variability and reduces the chance of operator errors. To address this need, a wide-field multispectral imaging system was developed that is capable of quantifying maps of PpIX in both liquid phantoms and in vivo experiments, focusing on high sensitivity light signals. The system uses both red and blue excitation to elicit a fluorescent response at varying skin depths. A ten-position filter wheel with bandpass filters ranging from 635nm to 710nm are used to capture images along the emission band. A linear least-square spectral fitting algorithm provides the ability to decouple background autofluorescence from PpIX fluorescence, which has improved the system sensitivity by an order of magnitude, detecting nanomolar PpIX concentrations in liquid phantoms in the presence of 2% whole blood and 2% intralipid.

Comparative Evaluation of the Antimicrobial Properties of Glass Ionomer Cements with and without Chlorhexidine Gluconate.

Science.gov (United States)

Yadiki, Josna Vinutha; Jampanapalli, Sharada Reddy; Konda, Suhasini; Inguva, Hema Chandrika; Chimata, Vamsi Krishna

2016-01-01

Chlorhexidine gluconate is a widely used antimicrobial agent. Adding chlorhexidine and quaternary ammonium compounds to filling materials, such as composite resins, acrylic resins, and glass ionomer cements increases the antibacterial property of restorative materials. This study includes antibacterial property of glass ionomer restorative cements with chlorhexidine gluconate. The primary objective of our study was to compare the antimicrobial properties of two commercially available glass ionomer cements with and without chlorhexidine gluconate on strains of mutans streptococci. Two glass ionomers (Fuji II Conventional and Fuji IX) were used. Chlorhexidine gluconate was mixed with glass ionomer cements, and antimicrobial properties against mutans streptococci were assessed by agar diffusion. The tested bacterial strain was inhibited and the antimicrobial properties decreased with time. The highest amount of antimicrobial activity with mean inhibitory zone was found in Fuji II with chlorhexidine gluconate followed by Fuji IX with chlorhexidine gluconate, Fuji II without chlorhexidine gluconate, and Fuji IX without chlorhexidine gluconate. The results of the study confirmed that the addition of 5% chlorhexidine gluconate to Fuji II and Fuji IX glass ionomer cements resulted in a restorative material that had increased antimicrobial properties over the conventional glass ionomer cements alone for Streptococcus mutans. How to cite this article: Yadiki JV, Jampanapalli SR , Konda S, Inguva HC, Chimata VK. Comparative Evaluation of the Antimicrobial Properties of Glass Ionomer Cements with and without Chlorhexidine Gluconate. Int J Clin Pediatr Dent 2016;9(2):99-103.

6th European symposium on uroradiology

International Nuclear Information System (INIS)

Bujlov, V.M.

1999-01-01

Materials of the 6th European symposium on uroradiology held in Strasbourg (France) in September, 1998. Symposium topics included problems of radiological diagnosis of kidneys, renovascular hypertension, man and woman sterility, pelvis organs of men and women, functional studies of lower urinary tract, pediatric and interventional uroradiology. Great attention is paid to magnetic resonance tomography, ultrasonography and conventional biomedical radiography [ru

Title IX and Sexual Harassment of Student Athletes.

Science.gov (United States)

Wolohan, John T.

1995-01-01

This article reviews what constitutes sexual harassment in sports by examining Title IX of the Education Amendments of 1972 and the effect it has had on charges of sexual harrassment in educational institutions. Athletic administrators are provided with strategies and recommendations to help schools and athletic departments develop sexual…

Fifth International Symposium on the Natural Radiation Environment

International Nuclear Information System (INIS)

Porstendoerfer, J.; Swedjemark, G.A.; Baeverstam, U.; Lowder, W.M.; Miller, K.M.; Fisenne, I.M.

1993-01-01

The fifth International Symposium on the Natural Radiation Environment organized a series of tutorial sessions. One of the five major fields concerned with the radon issue. The tutorials dealt with important issues of the radon problem and covered the following aspects: Cosmic and Terrestrial Gamma Radiation Measurement, Properties and Behaviour of Radon and Thoron and Their Decay Products in the Air, Radon and Radon Daughters Metrology: Basic Aspects Long Lived Radionuclides in the Environment, in Food and in Human Beings, Design and Analysis of Radon Surveys with Epidemiological Utility

Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice.

Science.gov (United States)

Verma, Dheeraj; Moghimi, Babak; LoDuca, Paul A; Singh, Harminder D; Hoffman, Brad E; Herzog, Roland W; Daniell, Henry

2010-04-13

To address complications of pathogenic antibody or life-threatening anaphylactic reactions in protein replacement therapy for patients with hemophilia or other inherited protein deficiencies, we have developed a prophylactic protocol using a murine hemophilia B model. Oral delivery of coagulation factor IX fused with cholera toxin beta-subunit (with or without a furin cleavage site; CTB-FFIX or CTB-FIX), expressed in chloroplasts (up to 3.8% soluble protein or 0.4 mg/g leaf tissue), bioencapsulated in plant cells, effectively blocked formation of inhibitory antibodies (undetectable or up to 100-fold less than controls). Moreover, this treatment eliminated fatal anaphylactic reactions that occurred after four to six exposures to intravenous F.IX. Whereas only 20-25% of control animals survived after six to eight F.IX doses, 90-93% of F.IX-fed mice survived 12 injections without signs of allergy or anaphylaxis. Immunostaining confirmed delivery of F.IX to Peyer's patches in the ileum. Within 2-5 h, feeding of CTB-FFIX additionally resulted in systemic delivery of F.IX antigen. This high-responder strain of hemophilia B mice represents a new animal model to study anaphylactic reactions. The protocol was effective over a range of oral antigen doses (equivalent to 5-80 microg recombinant F.IX/kg), and controlled inhibitor formation and anaphylaxis long-term, up to 7 months (approximately 40% life span of this mouse strain). Oral antigen administration caused a deviant immune response that suppressed formation of IgE and inhibitory antibodies. This cost-effective and efficient approach of antigen delivery to the gut should be applicable to several genetic diseases that are prone to pathogenic antibody responses during treatment.

Significant performance enhancement of inverted organic light-emitting diodes by using ZnIx as a hole-blocking layer

Science.gov (United States)

Cheng, Chuan-Hui; Zhang, Bi-Long; Sun, Chao; Li, Ruo-Xuan; Wang, Yuan; Tian, Wen-Ming; Zhao, Chun-Yi; Jin, Sheng-Ye; Liu, Wei-Feng; Luo, Ying-Min; Du, Guo-Tong; Cong, Shu-Lin

2017-06-01

A highly efficient inverted organic light emitting diode using 1.0 nm-thick ZnIx as a hole-blocking layer is developed. We fabricate devices with the configuration ITO/ZnIx (1.0 nm)/Alq3 (50 nm)/NPB (50 nm)/MoO3 (6.0 nm)/Al (100 nm). The deposition of a ZnIx layer increases the maximum luminance by two orders of magnitude from 13.4 to 3566.1 cd/m2. In addition, the maximum current efficiency and power efficiency are increased by three orders of magnitude, and the turn-on voltage to reach 1 cd/m2 decreases from 13 to 8 V. The results suggest that the electron injection efficiency is not improved by introducing a ZnIx layer. Instead, the improved device performance originates from the strong hole-blocking ability of ZnIx. This work indicates that layered materials may lead to novel applications in optoelectronic devices.

7th International Symposium on Gaseous Dielectrics

CERN Document Server

James, David

1994-01-01

The Seventh International Symposium on Gaseous Dielectrics was held in Knoxville, Tennessee, U. S. A. , on April 24-28, 1994. The symposium continued the interdisciplinary character and comprehensive approach of the preceding six symposia. Gaseous DielecIries VII is a detailed record of the symposium proceedings. It covers recent advances and developments in a wide range of basic, applied and industrial areas of gaseous dielectrics. It is hoped that Gaseous DielecIries VII will aid future research and development in, and encourage wider industrial use of, gaseous dielectrics. The Organizing Committee of the Seventh International Symposium on Gaseous Dielectrics consisted of G. Addis (U. S. A. ), L. G. Christophorou (U. S. A. ), F. Y. Chu (Canada), A. H. Cookson (U. S. A. ), O. Farish (U. K. ), I. Gallimberti (Italy) , A. Garscadden (U. S. A. ), D. R. James (U. S. A. ), E. Marode (France), T. Nitta (Japan), W. Pfeiffer (Germany), Y. Qiu (China), I. Sauers (U. S. A. ), R. J. Van Brunt (U. S. A. ), and W. Zaengl...

Hubungan Gaya Kepemimpinan Orang Tua terhadap Hasil Belajar IPA Siswa Kelas IX SMPN 2 Batang Anai

Directory of Open Access Journals (Sweden)

Nelfi Erlinda

2017-02-01

Full Text Available AbstractPenelitian ini dilatarbelakangi oleh rendahnya hasil belajar IPA siswa kelas IX SMPN 2 Batang Anai. Faktor penyebabnya ada yang berasal dari dalam diri siswa dan dari luar diri siswa. Faktor yang berasal dari dalam diri siswa seperti malas belajar. Faktor luar diri siswa seperti faktor lingkungan keluarga yang terdiri dari faktor orang tua, suasana keluarga, lingkungan keluarga, kondisi keluarga yang tidak sehat atau broken home. Hal ini berpengaruh dalam proses belajar dan hasil belajar siswa di sekolah. Penelitian ini bertujuan untuk mengetahui hubungan gaya kepemimpinan orang tua terhadap hasil belajar IPA siswa kelas IX SMPN 2 Batang Anai. Jenis penelitian ini adalah penelitian deskriptif. Populasi penelitian adalah semua siswa kelas IX SMPN 2 Batang Anai yang terdaftar dalam tahun ajaran  2016/2017. Sampel penelitian adalah semua kelas IX SMPN 2 Batang Anai. Teknik pengambilan sampel menggunakan total sampling. Instrumen penelitian yang digunakan berupa angket atau kuesioner yang diberikan ke siswa. Teknik analisis data yang digunakan untuk menguji hipotesis adalah analisis korelasi dengan menggunakan uji chi kuadrat untuk melihat antara hubungan gaya kepemimpinan oramg tua dengan hasil belajar IPA siswa kelas IX SMPN 2 Batang Anai. Berdasarkan analisis data didapatkan dua gaya kepemimpimam yaitu otoriter dan demokratis. Hasil uji hipotesis diperoleh X2hitung < X2tabel = 0,004 < 3,841  sehingga hipotesis Ho diterima pada taraf nyata 0,05 dan hipotesis Hi ditolak. Jadi tidak ada hubungan yang berarti antara gaya kepemimpinan orang tua terhadap hasil belajar IPA siswa kelas IX SMPN 2 Batang Anai. Kata kunci :  Gaya kepemimpinan orang tua, hasil belajar.

NATO Symposium on Human Detection and Diagnosis of System Failures

CERN Document Server

Rouse, William

1981-01-01

This book includes all of the papers presented at the NATO Symposium on Human Detection and Diagnosis of System Failures held at Roskilde, Denmark on August 4-8, 1980. The Symposium was sponsored by the Scientific Affairs Division of NATO and the Rise National Laboratory of Denmark. The goal of the Symposium was to continue the tradition initiated by the NATO Symposium on Monitoring Behavior and Supervisory Control held in Berchtesgaden, F .R. Germany in 1976 and the NATO Symposium on Theory and Measurement of Mental Workload held in Mati, Greece in 1977. To this end, a group of 85 psychologists and engineers coming from industry, government, and academia convened to discuss, and to generate a "state-of-the-art" consensus of the problems and solutions associated with the human IS ability to cope with the increasing scale of consequences of failures within complex technical systems. The Introduction of this volume reviews their findings. The Symposium was organized to include brief formal presentations of pape...

Tissue factor-dependent activation of tritium-labeled factor IX and factor X in human plasma

International Nuclear Information System (INIS)

Morrison, S.A.; Jesty, J.

1984-01-01

A comparism was made of the tissue factor-dependent activation of tritium-labeled factor IX and factor X in a human plasma system and a study was made of the role of proteases known to stimulate factor VII activity. Plasma was defibrinated by heating and depleted of its factors IX and X by passing it through antibody columns. Addition of human brain thromboplastin, Ca2+, and purified 3H-labeled factor X to the plasma resulted, after a short lag, in burst-like activation of the factor X, measured as the release of radiolabeled activation peptide. The progress of activation was slowed by both heparin and a specific inhibitor of factor Xa but factor X activation could not be completely abolished by such inhibitors. In the case of 3H-factor IX activation, the rate also increased for approximately 3 min after addition of thromboplastin, but was not subsequently curtailed. A survey of proteases implicated as activators of factor VII in other settings showed that both factor Xa and factor IXa could accelerate the activation of factor IX. However, factor Xa was unique in obliterating activation when present at concentrations greater than approximately 1 nM. Heparin inhibited the tissue factor-dependent activation of factor IX almost completely, apparently through the effect of antithrombin on the feedback reactions of factors Xa and IXa on factor VII. These results suggest that a very tight, biphasic control of factor VII activity exists in human plasma, which is modulated mainly by factor Xa. At saturation of factor VIIa/tissue factor, factor IX activation was significantly more rapid than was previously found in bovine plasma under similar conditions. The activation of factor X at saturation was slightly more rapid than in bovine plasma, despite the presence of heparin

Persuasive Writing and the Student-Run Symposium

Science.gov (United States)

Mayer, James C.

2007-01-01

High school teacher James C. Mayer explains how a student-run symposium can promote "risk-taking and participation" and help students practice effective persuasion skills before demonstrating them in writing. The symposium places students in roles that encourage responsibility and ownership for discussion and learning, shifting the classroom…

23. IX korraldab Vaala galerii kunstioksjoni "Väliseesti eri"

Index Scriptorium Estoniae

2004-01-01

Oksjonil on esindatud Eerik Haamer, Jaan Grünberg, Arno Vihalemm, Eduard Wiiralt, Ruth Tulving, Endel Kõks, Harald Jürissaar, Otto Paas, Ville Tops, Otto Puusta. Töödega saab tutvuda alates 18. IX, traditsiooniline sügisoksjon toimub 18. XI

11. European cosmic ray symposium held at Balatonfuered, Hungary, August 21-27, 1988

International Nuclear Information System (INIS)

1988-08-01

The biannual Symposium includes all aspects of cosmic ray research. The scientific programme was organized under three main headings: Cosmic rays in the heliosphere, Cosmic rays in the interstellar and extragalactic space, Properties of high-energy interactions as studied by cosmic rays. Selected short communications out of 114 contributed papers were indexed separately for the INIS database. (R.P.)

Efficacy of a high-purity factor IX concentrate in hemophilia B patients undergoing surgery Eficácia do concentrado de alta pureza do fator IX em pacientes cirúrgicos portadores de hemofilia B

Directory of Open Access Journals (Sweden)

Vesa Rasi

2002-04-01

Full Text Available A plasma derived, high purity, solvent-detergent treated and subsequently nanofiltered factor IX concentrate (BEMOFIL was evaluated in 19 hemophilia B patients, including four with severe, thirteen with mild or moderate type of disease and two hemophilia B carriers undergoing 31 surgical procedures. The mean in vivo recovery was 52 %, range 36 - 76 %. The mean preoperative plasma factor IX activity after the initial loading dose was 0.86 IU mL-1, range 0.59 - 1.32 IU mL-1. In eight major orthopedic procedures, the mean usage of factor IX was 44600 IU or 574 IU kg-1 during the hospital stay, mean 11.6 days. Thromboprophylaxis was not used. The hemostatic efficacy was evaluated good in all cases and there were no thromboembolic complications. In conclusion, BEMOFIL used as bolus dosing was found to be safe and effective in achieving hemostasis in subjects with hereditary F IX deficiency undergoing surgery.O concentrado de fator IX ( Bemofil , um derivado plasmático de alta pureza tratado com solventes- detergente e nano-filtrado , foi avaliado em 19 pacientes portadores de Hemofilia B .Quatro pacientes apresentavam a forma grave da moléstia, 13 a forma leve e moderada e dois portadores em um total de 31 atos cirúrgicos.A recuperação média "in vivo" foi de 52% (36-76%. A atividade plasmática média pré-operatória do fator IX após a dose inicial foi de 0,86 UI ml -1 , média de 0,59 - 1,32 UI ml-1. Em oito procedimentos ortopédicos extensos , a média de utilização do fator IX foi de 44.600 UI ou 574 UI kg -1 durante a hospitalização que teve a média de 11,6 dias. A tromboprofilaxia não foi utilizada. A eficácia hemostática avaliada em todos os casos foi boa ,e não ocorreu nenhum tipo de complicação tromboembólica. Concluímos que o Bemofil em bolus foi considerado seguro e eficaz para a hemostasia em pacientes portadores de hemofilia B que necessitam de um procedimento cirúrgico.

Ares I-X Ground Diagnostic Prototype

Science.gov (United States)

Schwabacher, Mark A.; Martin, Rodney Alexander; Waterman, Robert D.; Oostdyk, Rebecca Lynn; Ossenfort, John P.; Matthews, Bryan

2010-01-01

The automation of pre-launch diagnostics for launch vehicles offers three potential benefits: improving safety, reducing cost, and reducing launch delays. The Ares I-X Ground Diagnostic Prototype demonstrated anomaly detection, fault detection, fault isolation, and diagnostics for the Ares I-X first-stage Thrust Vector Control and for the associated ground hydraulics while the vehicle was in the Vehicle Assembly Building at Kennedy Space Center (KSC) and while it was on the launch pad. The prototype combines three existing tools. The first tool, TEAMS (Testability Engineering and Maintenance System), is a model-based tool from Qualtech Systems Inc. for fault isolation and diagnostics. The second tool, SHINE (Spacecraft Health Inference Engine), is a rule-based expert system that was developed at the NASA Jet Propulsion Laboratory. We developed SHINE rules for fault detection and mode identification, and used the outputs of SHINE as inputs to TEAMS. The third tool, IMS (Inductive Monitoring System), is an anomaly detection tool that was developed at NASA Ames Research Center. The three tools were integrated and deployed to KSC, where they were interfaced with live data. This paper describes how the prototype performed during the period of time before the launch, including accuracy and computer resource usage. The paper concludes with some of the lessons that we learned from the experience of developing and deploying the prototype.

IX Jornadas de educación emocional. Educación emocional y valores

OpenAIRE

Barredo Gutiérrez, Blanca; Bisquerra Alzina, Rafael; Blanco Cuch, Aida; Giner, Antoni; Pérez Escoda, Núria; Tey, Amèlia

2013-01-01

Barredo Gutierrez, B.; Bisquerra Alzina, R.; Blanco Cuch, A.; Giner Tarrida, A.; Perez Escoda, N.; Tey Teijón, A. (eds.) IX Jornades d’educació emocional. Educació emocional i valors / IX Jornadas de educación emocional. Educación emocional y valores. Barcelona, Universitat de Barcelona (Institut de Ciències de l’Educació), 2013. Document electrònic.valores. Barcelona, Universitat de Barcelona (Institut de Ciències de l’Educació), 2013. Document electrònic

Symposium on Differential Geometry and Differential Equations

CERN Document Server

Berger, Marcel; Bryant, Robert

1987-01-01

The DD6 Symposium was, like its predecessors DD1 to DD5 both a research symposium and a summer seminar and concentrated on differential geometry. This volume contains a selection of the invited papers and some additional contributions. They cover recent advances and principal trends in current research in differential geometry.

Radiation Damage in Reactor Materials. Part of the Proceedings of the Symposium on Radiation Damage in Solids and Reactor Materials

Energy Technology Data Exchange (ETDEWEB)

NONE

1963-08-15

Radiation damage has presented a new design parameter for the selection of materials to be used in fuel and cladding elements, moderators, structural components and pressure vessels in nuclear reactors. The severe and novel requirements for certain optimum combinations of physical and nuclear properties have emphasized the need for a better understanding of the basic mechanisms of radiation damage. This knowledge is not only essential for progress in the field of nuclear energy, but has direct applications to space technology and semi-conductor research as well. The IAEA, as part of its programme of promoting nuclear technology, therefore convened the Symposium on Radiation Damage in Solids and Reactor Materials, 7-11 May 1962. At the invitation of, and with generous material assistance from, the Government of Italy, the Symposium was held at Venice. The Symposium was primarily concerned with the investigation of the fundamental processes of radiation that underlie the behaviour of metals, alloys and ceramics that are actually useful or potentially useful reactor materials. Two sessions were devoted to studies of irradiation effects on simple metals, as these effects are easiest to interpret. Other topics included general theory, alloys, fissionable and moderator materials and special experimental techniques for radiation damage studies. The properties influenced by irradiation which were of main concern were those of primary importance to the behaviour of solids as reactor materials (e. g. dimensional stability, phase transformation, radiation hardening, fracture, fission-gas escape from uranium and its compounds). Other properties, such as optical, electrical and magnetic properties, and effects on semiconductors, ionic and other non-metallic crystals are also of interest in that these studies can increase our knowledge of the mechanism of radiation damage in solids and provide a tool for investigation into the physics of the solid state by offering a means of

Radiation Damage in Reactor Materials. Part of the Proceedings of the Symposium on Radiation Damage in Solids and Reactor Materials

International Nuclear Information System (INIS)

1963-01-01

Radiation damage has presented a new design parameter for the selection of materials to be used in fuel and cladding elements, moderators, structural components and pressure vessels in nuclear reactors. The severe and novel requirements for certain optimum combinations of physical and nuclear properties have emphasized the need for a better understanding of the basic mechanisms of radiation damage. This knowledge is not only essential for progress in the field of nuclear energy, but has direct applications to space technology and semi-conductor research as well. The IAEA, as part of its programme of promoting nuclear technology, therefore convened the Symposium on Radiation Damage in Solids and Reactor Materials, 7-11 May 1962. At the invitation of, and with generous material assistance from, the Government of Italy, the Symposium was held at Venice. The Symposium was primarily concerned with the investigation of the fundamental processes of radiation that underlie the behaviour of metals, alloys and ceramics that are actually useful or potentially useful reactor materials. Two sessions were devoted to studies of irradiation effects on simple metals, as these effects are easiest to interpret. Other topics included general theory, alloys, fissionable and moderator materials and special experimental techniques for radiation damage studies. The properties influenced by irradiation which were of main concern were those of primary importance to the behaviour of solids as reactor materials (e. g. dimensional stability, phase transformation, radiation hardening, fracture, fission-gas escape from uranium and its compounds). Other properties, such as optical, electrical and magnetic properties, and effects on semiconductors, ionic and other non-metallic crystals are also of interest in that these studies can increase our knowledge of the mechanism of radiation damage in solids and provide a tool for investigation into the physics of the solid state by offering a means of

Inactivation of Dengue and Yellow Fever viruses by heme, cobalt-protoporphyrin IX and tin-protoporphyrin IX.

Science.gov (United States)

Assunção-Miranda, I; Cruz-Oliveira, C; Neris, R L S; Figueiredo, C M; Pereira, L P S; Rodrigues, D; Araujo, D F F; Da Poian, A T; Bozza, M T

2016-03-01

To investigate the effect of heme, cobalt-protoporphyrin IX and tin-protoporphyrin IX (CoPPIX and SnPPIX), macrocyclic structures composed by a tetrapyrrole ring with a central metallic ion, on Dengue Virus (DENV) and Yellow Fever Virus (YFV) infection. Treatment of HepG2 cells with heme, CoPPIX and SnPPIX after DENV infection reduced infectious particles without affecting viral RNA contents in infected cells. The reduction of viral load occurs only with the direct contact of DENV with porphyrins, suggesting a direct effect on viral particles. Previously incubation of DENV and YFV with heme, CoPPIX and SnPPIX resulted in viral particles inactivation in a dose-dependent manner. Biliverdin, a noncyclical porphyrin, was unable to inactivate the viruses tested. Infection of HepG2 cells with porphyrin-pretreated DENV2 results in a reduced or abolished viral protein synthesis, RNA replication and cell death. Treatment of HepG2 or THP-1 cell lineage with heme or CoPPIX after DENV infection with a very low MOI resulted in a decreased DENV replication and protection from death. Heme, CoPPIX and SnPPIX possess a marked ability to inactivate DENV and YFV, impairing its ability to infect and induce cytopathic effects on target cells. These results open the possibility of therapeutic application of porphyrins or their use as models to design new antiviral drugs against DENV and YFV. © 2016 The Society for Applied Microbiology.

Systemic component of protoporphyrin IX production in nude mouse skin upon topical application of aminolevulinic acid depends on the application conditions

NARCIS (Netherlands)

van den Akker, Johanna T. H. M.; Iani, Vladimir; Star, Willem M.; Sterenborg, Henricus J. C. M.; Moan, Johan

2002-01-01

Topical application of 5-aminolevulinic acid (ALA) for protoporphyrin IX (PpIX)-based photodynamic therapy of skin cancer is generally considered not to induce systemic side effects because PpIX is supposed to be formed locally. However, earlier studies with topically applied ALA have revealed that

Absence of collagen IX accelerates hypertrophic differentiation in the embryonic mouse spine through a disturbance of the Ihh-PTHrP feedback loop.

Science.gov (United States)

Kamper, Matthias; Paulsson, Mats; Zaucke, Frank

2017-02-01

Collagen IX (Col IX) is a component of the cartilage extracellular matrix and contributes to its structural integrity. Polymorphisms in the genes encoding the Col IX ɑ2- and ɑ3-chains are associated with early onset of disc degeneration. Col IX-deficient mice already display changes in the spine at the newborn stage and premature disc degeneration starting at 6 months of age. To determine the role of Col IX in early spine development and to identify molecular mechanisms underlying disc degeneration, the embryonic development of the spine was analyzed in Col IX -/- mice. Histological staining was used to show tissue morphology at different time points. Localization of extracellular matrix proteins as well as components of signaling pathways were analyzed by immunohistochemistry. Developing vertebral bodies of Col IX -/- mice were smaller and already appeared more compact at E12.5. At E15.5, vertebral bodies of Col IX -/- mice revealed an increased number of hypertrophic chondrocytes as well as enhanced staining for the terminal differentiation markers alkaline phosphatase and collagen X. This correlates with an imbalance in the Ihh-PTHrP signaling pathway at this time point, reflected by an increase of Ihh and a concomitant decrease of PTHrP expression. An accelerated hypertrophic differentiation caused by a disturbed Ihh-PTHrP signaling pathway may lead to a higher bone mineral density in the vertebral bodies of newborn Col IX -/- mice and, as a result, to the early onset of disc degeneration.

8th International symposium on transport phenomena in combustion

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-31

The 8th International Symposium on Transport Phenomena in Combustion will be held in San Francisco, California, U.S.A., July 16-20, 1995, under the auspices of the Pacific Center of Thermal-Fluids Engineering. The purpose of the Symposium is to provide a forum for researchers and practitioners from around the world to present new developments and discuss the state of the art and future directions and priorities in the areas of transport phenomena in combustion. The Symposium is the eighth in a series; previous venues were Honolulu 1985, Tokyo 1987, Taipei 1988, Sydney 1991, Beijing 1992, Seoul 1993 and Acapulco 1994, with emphasis on various aspects of transport phenomena. The current Symposium theme is combustion. The Symposium has assembled a balanced program with topics ranging from fundamental research to contemporary applications of combustion theory. Invited keynote lecturers will provide extensive reviews of topics of great interest in combustion. Colloquia will stress recent advances and innovations in fire spread and suppression, and in low NO{sub x} burners, furnaces, boilers, internal combustion engines, and other practical combustion systems. Finally, numerous papers will contribute to the fundamental understanding of complex processes in combustion. This document contains abstracts of papers to be presented at the Symposium.

Verslag symposium : "M€€r welzijn zonder pijn"

NARCIS (Netherlands)

Driesse, M.; Kluivers-Poodt, M.

2010-01-01

Op 27 april 2010 hield men in Lelystad het symposium 'Meer welzijn zonder pijn' over het thema welzijn bij landbouwhuisdieren, georganiseerd door Wageningen UR Livestock Research in samenwerking met Boehringer Ingelheim. Hoewel het symposium primair bedoeld was voor rundvee- en varkensdierenartsen,

Highlight: IDRC sponsors Caribbean symposium on impact of ...

International Development Research Centre (IDRC) Digital Library (Canada)

12 mai 2015 ... An IDRC-sponsored symposium exploring the impact of the Internet on economic ... Le symposium commandité par le CRDI, qui a eu lieu à Saint Andrew, ... Une nouvelle recherche fait état d'arguments convaincants pour ...

Proceedings of the international nuclear power plant aging symposium

International Nuclear Information System (INIS)

Beranek, A.

1989-03-01

This report presents the proceedings of the International Nuclear Power Plant Aging Symposium that was held at the Hyatt Regency Hotel in Bethesda, Maryland, on August 30-31 and September 1, 1988. The Symposium was presented in cooperation with the American Nuclear Society, the American Society of Civil Engineers, the American Society of Mechanical Engineers, and the Institute of Electrical and Electronics Engineers. There were approximately 550 participants from 16 countries at the Symposium

Comparison of protoporphyrin IX content and related gene expression in the tissues of chickens laying brown-shelled eggs.

Science.gov (United States)

Li, Guangqi; Chen, Sirui; Duan, Zhongyi; Qu, Lujiang; Xu, Guiyun; Yang, Ning

2013-12-01

Protoporphyrin IX (PpIX), an immediate precursor of heme, is the main pigment resulting in the brown coloration of eggshell. The brownness and uniformity of the eggshell are important marketing considerations. In this study, 9 chickens laying darker brown shelled eggs and 9 chickens laying lighter brown shelled eggs were selected from 464 individually caged layers in a Rhode Island Red pureline. The PpIX contents were measured with a Microplate Reader at the wavelength of 412 nm and were compared in different tissues of the 2 groups. Although no significant difference in serum, bile, and excreta was found between the 2 groups, PpIX content in the shell gland and eggshell of the darker group was higher than in those of the lighter group, suggesting that PpIX was synthesized in the shell gland. We further determined the expression levels of 8 genes encoding enzymes involved in the heme synthesis and transport in the liver and shell gland at 6 h postoviposition by quantitative PCR. The results showed that expression of aminolevulinic acid synthase-1 (ALAS1) was higher in the liver of hens laying darker brown shelled eggs, whereas in the shell gland the expression levels of ALAS1, coproporphyrinogen oxidase (CPOX), ATP-binding cassette family members ABCB7 and ABCG2, and receptor for feline leukemia virus, subgroup C (FLVCR) were significantly higher in the hens laying darker brown shelled eggs. Our results demonstrated that hens laying darker brown shelled eggs could deposit more PpIX onto the eggshell and the brownness of the eggshell was dependent on the total quantity of PpIX in the eggshell. More heme was synthesized in the liver and shell gland of hens laying darker brown shelled eggs than those of hens laying lighter brown shelled eggs. High expression level of ABCG2 might facilitate the accumulation of PpIX in the shell gland.

Introduction and Overview of the Symposium Anil Kumar (Indian ...

Indian Academy of Sciences (India)

First page Back Continue Last page Overview Graphics. Introduction and Overview of the Symposium Anil Kumar (Indian Institute of Science, Bangalore). Symposium on Quantum Computing and Quantum Information. Notes:

Conserving biodiversity on native rangelands: Symposium proceedings

Science.gov (United States)

Daniel W. Uresk; Greg L. Schenbeck; James T. O' Rourke

1997-01-01

These proceedings are the result of a symposium, "Conserving biodiversity on native rangelands" held on August 17, 1995 in Fort Robinson State Park, NE. The purpose of this symposium was to provide a forum to discuss how elements of rangeland biodiversity are being conserved today. We asked, "How resilient and sustainable are rangeland systems to the...

Phase-space dynamics of Bianchi IX cosmological models

International Nuclear Information System (INIS)

Soares, I.D.

1985-01-01

The complex phase-space dynamical behaviour of a class of Biachi IX cosmological models is discussed, as the chaotic gravitational collapse due Poincare's homoclinic phenomena, and the n-furcation of periodic orbits and tori in the phase space of the models. Poincare maps which show this behaviour are constructed merically and applications are discussed. (Author) [pt

IUTAM Symposium

CERN Document Server

Pedley, Timothy

2003-01-01

The IUTAM Symposium on Flow in Collapsible Tubes and Past Other Highly Compliant Boundaries was held on 26-30 March, 2001, at the University of Warwick. As this was the first scientific meeting of its kind we considered it important to mark the occasion by producing a book. Accordingly, at the end of the Symposium the Scientific Committee met to discuss the most appropriate format for the book. We wished to avoid the format of the conventional conference book consisting of a large number of short articles of varying quality. It was agreed that instead we should produce a limited number of rigorously refereed and edited articles by selected participants who would aim to sum up the state of the art in their particular research area. The outcome is the present book. Peter W. Ca rpenter, Warwick Timothy J. Pedley, Cambridge May, 2002. VB SCIENTIFIC COMMITTEE Co-Chair: P.W. Carpenter, Engineering, Warwiek, UK Co-Chair: TJ. Pedley, DAMTP, Cambridge, UK V.V. Babenko, Hydromechanics, Kiev, Ukraine R. Bannasch, Bionik...

Factor IX[sub Madrid 2]: A deletion/insertion in Facotr IX gene which abolishes the sequence of the donor junction at the exon IV-intron d splice site

Energy Technology Data Exchange (ETDEWEB)

Solera, J. (Unidades de Genetica Molecular, Madrid (Spain)); Magallon, M.; Martin-Villar, J. (Hemofilia Hospital, Madrid (Spain)); Coloma, A. (Departamento deBioquimica de la Facultad de Medicina de la Universidad Autonoma, Madrid (Spain))

1992-02-01

DNA from a patient with severe hemophilia B was evaluated by RFLP analysis, producing results which suggested the existence of a partial deletion within the factor IX gene. The deletion was further localized and characterized by PCR amplification and sequencing. The altered allele has a 4,442-bp deletion which removes both the donor splice site located at the 5[prime] end of intron d and the two last coding nucleotides located at the 3[prime] end of exon IV in the normal factor IX gene; this fragment has been inserted in inverted orientation. Two homologous sequences have been discovered at the ends of the deleted DNA fragment.

Microstructures and mechanical properties of aging materials

International Nuclear Information System (INIS)

Liaw, P.K.; Viswanathan, R.; Murty, K.L.; Simonen, E.P.; Frear, D.

1993-01-01

This book contains a collection of papers presented at the symposium on ''Microstructures and Mechanical Properties of Aging Materials,'' that was held in Chicago, IL. November 2-5, 1992 in conjunction with the Fall Meeting of The Minerals, Metals and Materials Society (TMS). The subjects of interest in the symposium included: (1) mechanisms of microstructural degradation, (2) effects of microstructural degradation on mechanical behavior, (3) development of life prediction methodology for in-service structural and electronic components, (4) experimental techniques to monitor degradation of microstructures and mechanical properties, and (5) effects of environment on microstructural degradation and mechanical properties. Individual papers have been processed separately for inclusion in the appropriate data bases

Study of primitive universe in the Bianchi IX model

International Nuclear Information System (INIS)

Matsas, G.E.A.

1988-03-01

The theory of general relativity is used to study the homogeneous cosmological model Bianch IX with isometry group SO(3) near the cosmological singularity. The Bogoyavlenskii-Novikov formalism to explain the anusual behaviour of the Liapunov exponent associated with this chaotic system, is introduced. (author) [pt

78 FR 10180 - Annual Computational Science Symposium; Conference

Science.gov (United States)

2013-02-13

...] Annual Computational Science Symposium; Conference AGENCY: Food and Drug Administration, HHS. ACTION... Pharmaceutical Users Software Exchange (PhUSE), is announcing a public conference entitled ``The FDA/PhUSE Annual Computational Science Symposium.'' The purpose of the conference is to help the broader community align and...

Special symposium issue 2: proceedings of the ninth symposium on thermophysical properties

International Nuclear Information System (INIS)

Hanley, H.J.M.; Cezairliyan, A.

1986-01-01

The topics covered in this issue include transport properties of polyatomic gases; measurements of the critical properties of sulfur hexafluoride by laser interferometry; measurements of vapor-liquid coexistence curves and critical loci for refrigerant mixtures; a crossover description of the thermodynamic properties of fluids in the critical region; thermal diffusion in ionic systems; thermal transport behavior of van der Waals solids and liquids; a heating system for the investigation of thermophysical properties of metals; high-pressure and high-temperature thermophysical measurements on rhenium, tantalum, and tungsten; and the therodynamic properties of vanadium

30th International Acoustical Imaging Symposium

CERN Document Server

Jones, Joie; Lee, Hua

2011-01-01

The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place every two years since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2009 the 30th International Symposium on Acoustical Imaging was held in Monterey, CA, USA, March 1-4. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 30 in the Series contains an excellent collection of forty three papers presented in five major categories: Biomedical Imaging Acoustic Microscopy Non-Destructive Evaluation Systems Analysis Signal Analysis and Image Processing Audience Researchers in medical imaging and biomedical instrumentation experts.

Proceedings of the second ERDA statistical symposium

Energy Technology Data Exchange (ETDEWEB)

Tietjen, G.; Campbell, K. (comps.)

1977-04-01

The Second ERDA Statistical Symposium, sponsored by the Energy Research and Development Administration, was held at Oak Ridge, Tennessee, October 25-27, 1976. This was the second annual symposium designed to promote interlaboratory communications among ERDA statisticians as well as contacts with statisticians from other institutions. The proceedings of the first symposium, held at Los Alamos in November, 1975, have been published by Batelle Pacific Northwest Laboratories (BNWL-1986). Separate abstracts were prepared for seven of the papers in this proceeding, all going in ERDA Energy Research Abstracts (ERA) and two in Energy Abstracts for Policy Analysis (EAPA). The remaining four have already been cited in ERA and can be found by referring to CONF-761023-- in the report number index. (RWR)

NIFS symposium: toward the research of fusion burning plasmas

International Nuclear Information System (INIS)

Itoh, Sanae

1993-07-01

NIFS symposium, entitled 'Toward the research of Fusion Burning Plasmas - Present status and Future Strategy' was held at NIFS on July 15th 1992. This NIFS symposium covers various topics related to burning plasma, e.g., JET DT experiment, Plan for DT experiment on TFTR as well as the future trends among researchers. To study the critical issues and trends of future research, a questionnaire was sent to about 100 researchers. This report presents such activities in the NIFS symposium. (author)

Proceedings of the 2012 symposium on nuclear data

International Nuclear Information System (INIS)

Nakajima, Ken; Hori, Jun-ichi

2013-10-01

The 2012 symposium on nuclear data organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) and Research Reactor Institute, Kyoto University (KURRI) was held at Kumatori, KURRI on Nov. 15th and 16th, 2012 in cooperation with Nuclear Science and Engineering Directorate of Japan Atomic Energy Agency. The symposium was devoted for presentations and discussions on the four topics: 'Nuclear Power after Fukushima Nuclear Plant Accident', 'Application of Nuclear Data', 'How Should We Deal with Covariances of Nuclear Data?' and 'Validation of JENDL-4.0 and Future', as well as poster sessions on various research fields. Tutorials on neutron resonance capture and transmission analysis, international trend of nuclear data research were also given in the symposium. Talks as well as posters presented at the symposium aroused lively discussions among approximately 83 participants. This report consists of total 35 papers including 13 oral presentations and 22 poster presentations. (author)

Inhibition of Carbonic Anhydrase IX by Ureidosulfonamide Inhibitor U104 Reduces Prostate Cancer Cell Growth, But Does Not Modulate Daunorubicin or Cisplatin Cytotoxicity.

Science.gov (United States)

Riemann, Anne; Güttler, Antje; Haupt, Verena; Wichmann, Henri; Reime, Sarah; Bache, Matthias; Vordermark, Dirk; Thews, Oliver

2018-03-05

Carbonic anhydrase (CA) IX has emerged as a promising target for cancer therapy. It is highly upregulated in hypoxic regions and mediates pH regulation critical for tumor cell survival as well as extracellular acidification of the tumor microenvironment, which promotes tumor aggressiveness via various mechanisms, such as augmenting metastatic potential. Therefore, the aim of this study was to analyze the complex interdependency between CA IX and the tumor microenvironment in prostate tumor cells with regard to potential therapeutic implications. CA IX was upregulated by hypoxia as well as acidosis in prostate cancer cells. This induction did not modulate intracellular pH but led to extracellular acidification. Pharmacological inhibition of CA IX activity by U104 (SLC-0111) resulted in a reduction in tumor cell growth and an increase in apoptotic cell death. Intracellular pH was reduced under normoxic and even more so under hypoxic conditions when CA IX level was high. However, although intracellular pH regulation was disturbed, targeting CA IX in combination with daunorubicin or cisplatin did not intensify apoptotic tumor cell death. Hence, targeting CA IX in prostate cancer cells can lead to intracellular pH dysregulation and, consequently, can reduce cellular growth and elevate apoptotic cell death. Attenuation of extracellular acidification by blocking CA IX might additionally impede tumor progression and metastasis. However, no beneficial effect was seen when targeting CA IX in combination with chemotherapeutic drugs.

Counselor Education and Title IX: Current Perceptions and Questions

Science.gov (United States)

Welfare, Laura E.; Wagstaff, Jennifer; Haynes, Jenna R.

2017-01-01

This national survey of counselor educator perceptions of the Title IX requirement to report student disclosures of gender-based discrimination revealed the need for greater clarity about faculty strategies for serving counseling program students while upholding the federal law. The authors describe the recent expansion of the requirements and…

3rd International Symposium on Innovative Management, Information and Production

CERN Document Server

Xu, Bing; Wu, Berlin

2014-01-01

Innovative Management in Information and Production is based on the proceedings of the Third International Symposium on Innovative Managemet, Information and Production. This symposium is held by International Society of Management Engineers. The symposium took place on October 8-10, in Ho Chi Minh City, Vietnam. This book examines recent innovative management of information and productions such as digital collection management and operations planning, scheduling and control.

Oscillating Bianchi IX universe in Horava-Lifshitz gravity

International Nuclear Information System (INIS)

Misonoh, Yosuke; Maeda, Kei-ichi; Kobayashi, Tsutomu

2011-01-01

We study a vacuum Bianchi IX universe in the context of Horava-Lifshitz gravity. In particular, we focus on the classical dynamics of the universe and analyze how anisotropy changes the history of the universe. For small anisotropy, we find an oscillating universe as well as a bounce universe just as the case of the Friedmann-Lemaitre-Robertson-Walker spacetime. However, if the initial anisotropy is large, we find the universe which ends up with a big crunch after oscillations if a cosmological constant Λ is zero or negative. For Λ>0, we find a variety of histories of the universe, that is a de Sitter expanding universe after oscillations in addition to the oscillating solution and the previous big crunch solution. This fate of the universe shows sensitive dependence of initial conditions, which is one of the typical properties of a chaotic system. If the initial anisotropy is near the upper bound, we find the universe starting from a big bang and ending up with a big crunch for Λ≤0, and a de Sitter expanding universe starting from a big bang for Λ>0.

Big Men on Campus: Administrative Response to Title IX and the Development of Women's Sports in the Big Ten Conference, 1972-1982

Science.gov (United States)

Ramsey, Jeffrey T.

2014-01-01

Signed into law in 1972, Title IX of the Education Amendments was designed to eliminate gender discrimination throughout the American educational system. Title IX applied to all educational programs at any level of schooling including admissions, financial aid, academic programs, and social organizations. However, Title IX has primarily been…

Correlation between macroscopic fluorescence and protoporphyrin IX content in psoriasis and actinic keratosis following application of aminolevulinic acid.

NARCIS (Netherlands)

Smits, T.; Robles, C.A.; Erp, P.E.J. van; Kerkhof, P.C.M. van de; Gerritsen, M.J.P.

2005-01-01

In fluorescence diagnosis with 5-aminolevulinic acid (ALA)-induced porphyrins (FDAP), protoporphyrin IX (PpIX) accumulation can be macroscopically visualized. Interpretation of these data is still problematic because of the low reproducibility of the procedure and poor understanding of the

Transmembrane carbonic anhydrase isozymes IX and XII in the female mouse reproductive organs

Directory of Open Access Journals (Sweden)

Tomas Eija

2004-10-01

Full Text Available Abstract Background Carbonic anhydrase (CA classically catalyses the reversible hydration of dissolved CO2 to form bicarbonate ions and protons. The twelve active CA isozymes are thought to regulate a variety of cellular functions including several processes in the reproductive systems. Methods The present study was designed to investigate the expression of transmembrane CAs, CA IX and XII, in the mouse uterus, ovary and placenta. The expression of CA IX and XII was examined by immunoperoxidase staining method and western blotting. CA II and XIII served as positive controls since they are known to be present in the mouse reproductive tract. Results The data of our study indicated that CA XII is expressed in the mouse endometrium. Only very faint signal was observed in the corpus luteum of the ovary and the placenta remained mainly negative. CA IX showed weak reaction in the endometrial epithelium, while it was completely absent in the ovary and placenta. Conclusion The conservation of CA XII expression in both mouse and human endometrium suggests a role for this isozyme in reproductive physiology.

The 2002 Starting Artificial Intelligence Researchers Symposium

OpenAIRE

Vidal, Thierry

2003-01-01

During the 2002 European Conference on Artificial Intelligence (ECAI-02) was introduced the Starting Artificial Intelligence Researchers Symposium STAIRS), the first-ever international symposium specifically aimed at Ph.D. students in AI. The outcome was a thorough, high-quality, and successful event, with all the features one usually finds in the best international conferences: large international committees, comprehensive coverage, published proceedings, renowned speakers and panelists, sub...

Welcome and introduction to symposium - Day 2

OpenAIRE

humanities, Symposium on Information and technology in the arts and; McLaughlin, Jeremy Lee; Matusiak, Krystyna

2015-01-01

Welcome and introduction slides used for presentation at Day 2 of the Virtual Symposium on Information and Technology in the Arts and Humanities, held April 22 and 23, 2015. The Symposium was co-sponsored by the ASIS&T (Association for Information Science and Technology) Special Interest Group for Arts and Humanities (SIG AH) and the Special Interest Group for Visualization, Images, and Sound (SIG VIS).

Nagasaki symposium on Chernobyl: Update and future. Proceedings

International Nuclear Information System (INIS)

Nagataki, Shigenobu

1994-01-01

This publication contains valuable, up-to-date scientific information on the health effects of the Chernobyl accident, obtained from almost all the leading international and national organizations. The purpose of the Nagasaki symposium on Chernobyl was to present and discuss the available data from all over the world independent of psychological, social, economic, and political bias, and thus to make conclusions that would further medical science. To this end, the symposium consisted of two sessions, 'Chernobyl update' and 'Chernobyl in the future'. Along with the proceedings of these two sessions, the proceedings of the Japan-NIS Chernobyl thyroid symposium, held in December 1993 are included in this book. (orig.)

The ILL millennium symposium and European user meeting

International Nuclear Information System (INIS)

Carlile, C.J.; Frick, B.; Radaelli, P.G.; Alba-Simionesco, C.; Chauty, A.; Niss, K.; Casas, F.; Sokolov, A.; Lequeux, F.; Montes, H.; Harrison, A.; Schurtenberger, P.; Dubbers, D.; Frank, A.; Gudel, H.U.; Wagner, R.; Vettier, C.; Gahler, R.; Protassov, K.; Geltenbort, P.; Plonka, C.; Simpson, G.; Pinston, J.A.; Genevey, J.; Urban, W.; Scherillo, A.; Orlandi, R.; Smith, A.G.; Mana, G.; Abele, H.; Van der Grinten, M.; Steuwer, A.; Klotz, S.; Hamel, G.; Strassle, C.Th.; Kervananois, N.; Koza, M.M.; Nishiyama, Y.; Langan, P.; Wada, M.; Sugiyama, J.; Chanzy, H.; Gunter, M.M.; Lerch, M.; Boysen, H.; Korte, C.; Suard, E.; Blanco, J.A.; Fernandez-Rodriguez, J.; Brown, P.J.; Stunault, A.; Katsumata, K.; Lovesey, S.W.; Iga, F.; Michimura, S.; Kremer, R.K.; Banks, M.; Capogna, L.; Enderle, M.; Gibson, B.J.; McIntyre, G.J.; Ouladdiaf, B.; Pujol, S.; Raggazzoni, J.L.; Rheinstadter, M.; Schefer, J.; Boehm, M.; Roessli, B.; Wills, A.S.; Ouladdiaf, B.; Lelievre-Berna, E.; Goff, J.P.; Toader, A.M.; Skoulatos, M.; Enderle, M.; Stewart, J.R.; Murani, A.; Roger, M.; Shannon, N.; Kaul, E.E.; Geibel, C.; Simonet, V.; Lhotel, E.; Paulsen, C.; Ressouche, E.; Staub, U.; Amato, A.; Baines, C.; Petrakovskii, G.A.; Bramwell, S.; Fukuhara, N.; Ebert, J.; Lindner, D.; Dauvergne, M.T.; Hartlein, M.; Timmins, P.; Conti, E.; Svergun, D.; Budayova-Spano, M.; Bonnete, F.; El Hajji, M.; Blakeley, M.P.; Meilleur, F.; Castro, B.; Gabel, F.; Ferrand, M.; Chenal, A.; Forge, V.; Fragneto, G.; Haertlein, M.; Gillet, D.; Haertlein, M.

2006-01-01

Five years ago the ILL (Institute Laue-Langevin) convened the first Millennium symposium in order to launch an ambitious modernization program of instruments and infrastructure known as the ILL Millennium Program. After 5 years of activity we have decided to run a second such symposium. The scientific program of this Millennium Symposium will address the following points: -) instrumental and scientific achievements made possible by the Millennium Program, -) trends in science and engineering and the implications for the ILL, -) scenarios for future instrumentation and user support facilities, and -) the scientific priorities of the user community. This document gathers the abstracts of 63 contributions and 73 posters

The ILL millennium symposium and European user meeting

Energy Technology Data Exchange (ETDEWEB)

Carlile, C.J.; Frick, B.; Radaelli, P.G.; Alba-Simionesco, C.; Chauty, A.; Niss, K.; Casas, F.; Sokolov, A.; Lequeux, F.; Montes, H.; Harrison, A.; Schurtenberger, P.; Dubbers, D.; Frank, A.; Gudel, H.U.; Wagner, R.; Vettier, C.; Gahler, R.; Protassov, K.; Geltenbort, P.; Plonka, C.; Simpson, G.; Pinston, J.A.; Genevey, J.; Urban, W.; Scherillo, A.; Orlandi, R.; Smith, A.G.; Mana, G.; Abele, H.; Van der Grinten, M.; Steuwer, A.; Klotz, S.; Hamel, G.; Strassle, C.Th.; Kervananois, N.; Koza, M.M.; Nishiyama, Y.; Langan, P.; Wada, M.; Sugiyama, J.; Chanzy, H.; Gunter, M.M.; Lerch, M.; Boysen, H.; Korte, C.; Suard, E.; Blanco, J.A.; Fernandez-Rodriguez, J.; Brown, P.J.; Stunault, A.; Katsumata, K.; Lovesey, S.W.; Iga, F.; Michimura, S.; Kremer, R.K.; Banks, M.; Capogna, L.; Enderle, M.; Gibson, B.J.; McIntyre, G.J.; Ouladdiaf, B.; Pujol, S.; Raggazzoni, J.L.; Rheinstadter, M.; Schefer, J.; Boehm, M.; Roessli, B.; Wills, A.S.; Ouladdiaf, B.; Lelievre-Berna, E.; Goff, J.P.; Toader, A.M.; Skoulatos, M.; Enderle, M.; Stewart, J.R.; Murani, A.; Roger, M.; Shannon, N.; Kaul, E.E.; Geibel, C.; Simonet, V.; Lhotel, E.; Paulsen, C.; Ressouche, E.; Staub, U.; Amato, A.; Baines, C.; Petrakovskii, G.A.; Bramwell, S.; Fukuhara, N.; Ebert, J.; Lindner, D.; Dauvergne, M.T.; Hartlein, M.; Timmins, P.; Conti, E.; Svergun, D.; Budayova-Spano, M.; Bonnete, F.; El Hajji, M.; Blakeley, M.P.; Meilleur, F.; Castro, B.; Gabel, F.; Ferrand, M.; Chenal, A.; Forge, V.; Fragneto, G.; Haertlein, M.; Gillet, D.; Haertlein, M

2006-07-01

Five years ago the ILL (Institute Laue-Langevin) convened the first Millennium symposium in order to launch an ambitious modernization program of instruments and infrastructure known as the ILL Millennium Program. After 5 years of activity we have decided to run a second such symposium. The scientific program of this Millennium Symposium will address the following points: -) instrumental and scientific achievements made possible by the Millennium Program, -) trends in science and engineering and the implications for the ILL, -) scenarios for future instrumentation and user support facilities, and -) the scientific priorities of the user community. This document gathers the abstracts of 63 contributions and 73 posters.

9th International Symposium on Lactic Acid Bacteria

NARCIS (Netherlands)

Kuipers, Oscar P.; Poolman, Berend; Hugenholtz, Jeroen

What’s new in the field of lactic acid bacteria? The 9th International Symposium on Lactic Acid Bacteria (LAB9) will take place 31 August to 4 September 2008 in Egmond aan Zee, The Netherlands. Traditionally, the triannual LAB symposium focuses on the themes of genetics, physiology, and applications

28th International Acoustical Imaging Symposium

CERN Document Server

André, Michael P; Andre, Michael; Arnold, Walter; Bamber, Jeff; Burov, Valentin; Chubachi, Noriyoshi; Erikson, Kenneth; Ermert, Helmut; Fink, Mathias; Gan, Woon S; Granz, Bernd; Greenleaf, James; Hu, Jiankai; Jones, Joie P; Khuri-Yakub, Pierre; Laugier, Pascal; Lee, Hua; Lees, Sidney; Levin, Vadim M; Maev, Roman; Masotti, Leonardo; Nowicki, Andrzej; O’Brien, William; Prasad, Manika; Rafter, Patrick; Rouseff, Daniel; Thijssen, Johan; Tittmann, Bernard; Tortoli, Piero; Steen, Anton; Waag, Robert; Wells, Peter; Acoustical Imaging

2007-01-01

The International Acoustical Imaging Symposium has been held continuously since 1968 as a unique forum for advanced research, promoting the sharing of technology, developments, methods and theory among all areas of acoustics. The interdisciplinary nature of the Symposium and the wide international participation are two of its main strengths. Scientists from around the world present their papers in an informal environment conducive to lively discussion and cross-fertilization. The fact that a loyal community of scientists has supported this Series since 1968 is evidence of its impact on the field. The Symposium Series continues to thrive in a busy calendar of scientific meetings without the infrastructure of a professional society. It does so because those who attend and those who rely on the Proceedings as a well-known reference work acknowledge its value. This Volume 28 of the Proceedings likewise contains an excellent collection of papers presented in six major categories, offering both a broad perspective ...

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Proceedings of the IX DAE-BRNS National Laser Symposium - Part I: Physics and ..... of a wide-aperture copper vapour laser with hydrogen additive in neon buffer gas .... X-ray photoelectron spectroscopy, high-resolution X-ray diffraction and ...

YOUNG STELLAR POPULATIONS IN MYStIX STAR-FORMING REGIONS: CANDIDATE PROTOSTARS

Energy Technology Data Exchange (ETDEWEB)

Romine, Gregory; Feigelson, Eric D.; Getman, Konstantin V. [Department of Astronomy and Astrophysics, Pennsylvania State University, 525 Davey Lab, University Park, PA 16802 (United States); Kuhn, Michael A. [Millennium Institute of Astrophysics, Camino El Observatorio 1515, Las Condes, Santiago (Chile); Povich, Matthew S., E-mail: edf@astro.psu.edu [Department of Physics and Astronomy, California State Polytechnic University, 3801 West Temple Ave., Pomona, CA 91768 (United States)

2016-12-20

The Massive Young Star-Forming Complex in Infrared and X-ray (MYStIX) project provides a new census on stellar members of massive star-forming regions within 4 kpc. Here the MYStIX Infrared Excess catalog and Chandra -based X-ray photometric catalogs are mined to obtain high-quality samples of Class I protostars using criteria designed to reduce extragalactic and Galactic field star contamination. A total of 1109 MYStIX Candidate Protostars (MCPs) are found in 14 star-forming regions. Most are selected from protoplanetary disk infrared excess emission, but 20% are found from their ultrahard X-ray spectra from heavily absorbed magnetospheric flare emission. Two-thirds of the MCP sample is newly reported here. The resulting samples are strongly spatially associated with molecular cores and filaments on Herschel far-infrared maps. This spatial agreement and other evidence indicate that the MCP sample has high reliability with relatively few “false positives” from contaminating populations. But the limited sensitivity and sparse overlap among the infrared and X-ray subsamples indicate that the sample is very incomplete with many “false negatives.” Maps, tables, and source descriptions are provided to guide further study of star formation in these regions. In particular, the nature of ultrahard X-ray protostellar candidates without known infrared counterparts needs to be elucidated.

YOUNG STELLAR POPULATIONS IN MYStIX STAR-FORMING REGIONS: CANDIDATE PROTOSTARS

International Nuclear Information System (INIS)

Romine, Gregory; Feigelson, Eric D.; Getman, Konstantin V.; Kuhn, Michael A.; Povich, Matthew S.

2016-01-01

The Massive Young Star-Forming Complex in Infrared and X-ray (MYStIX) project provides a new census on stellar members of massive star-forming regions within 4 kpc. Here the MYStIX Infrared Excess catalog and Chandra -based X-ray photometric catalogs are mined to obtain high-quality samples of Class I protostars using criteria designed to reduce extragalactic and Galactic field star contamination. A total of 1109 MYStIX Candidate Protostars (MCPs) are found in 14 star-forming regions. Most are selected from protoplanetary disk infrared excess emission, but 20% are found from their ultrahard X-ray spectra from heavily absorbed magnetospheric flare emission. Two-thirds of the MCP sample is newly reported here. The resulting samples are strongly spatially associated with molecular cores and filaments on Herschel far-infrared maps. This spatial agreement and other evidence indicate that the MCP sample has high reliability with relatively few “false positives” from contaminating populations. But the limited sensitivity and sparse overlap among the infrared and X-ray subsamples indicate that the sample is very incomplete with many “false negatives.” Maps, tables, and source descriptions are provided to guide further study of star formation in these regions. In particular, the nature of ultrahard X-ray protostellar candidates without known infrared counterparts needs to be elucidated.

Rapporteurs report of the symposium

International Nuclear Information System (INIS)

Myerscough, Dan

2014-01-01

The objective of the symposium was to share current practice, experiences and innovations within the management of contaminated metallic radioactive material. The symposium was a forum for: Learning about current practices, Highlight strategic issues related to metals recycling, Exchange of experiences, Discussion of innovative and new techniques and needs for improvements, Developing and maintenance of networks in the area of metals recycling. The aim was to bring together operators, regulators, decision makers, scientists, consultants, contractors and other stakeholders. A short introduction by representatives from Studsvik, IAEA and OECD/NEA started the symposium followed by presentations by invited speakers from international organisations. Seven topical sessions covered issues relating to: 1 - Regulations and recommendations: - International recommendations and national legislation, - Application of regulations, - Regulator views; 2 - Minimising waste amounts: - Experience in minimising the generation of waste in the form of radioactive or potentially radioactive metals, - Activities to minimise the waste volumes for disposal; 3 - Characterisation and categorisation of metals to be recycled; 4 - Decontamination of metals for clearance; 5 - Melting of metals for clearance, reuse or volume reduction; 6 - Best practice in management of metals for clearance and recycling; 7 - Sustainability and public acceptance. Each session contained three to five presentations and group discussions. Each session was concluded with a short analysis of the presentations and the outcome of the group discussions. Conclusions of each session and outcome of the group discussions were presented on a Summing up the third day. The symposium also held a poster session with topics as above. This report provides a short summary of the various presentations and discussions concentrating on the key messages and outcomes of the sessions

The scorpion toxin Bot IX is a potent member of the α-like family and has a unique N-terminal sequence extension.

Science.gov (United States)

Martin-Eauclaire, Marie-France; Salvatierra, Juan; Bosmans, Frank; Bougis, Pierre E

2016-09-01

We report the detailed chemical, immunological and pharmacological characterization of the α-toxin Bot IX from the Moroccan scorpion Buthus occitanus tunetanus venom. Bot IX, which consists of 70 amino acids, is a highly atypical toxin. It carries a unique N-terminal sequence extension and is highly lethal in mice. Voltage clamp recordings on oocytes expressing rat Nav1.2 or insect BgNav1 reveal that, similar to other α-like toxins, Bot IX inhibits fast inactivation of both variants. Moreover, Bot IX belongs to the same structural/immunological group as the α-like toxin Bot I. Remarkably, radioiodinated Bot IX competes efficiently with the classical α-toxin AaH II from Androctonus australis, and displays one of the highest affinities for Nav channels. © 2016 Federation of European Biochemical Societies.

Proceedings of DAE-BRNS national symposium on Limnology

International Nuclear Information System (INIS)

Venkataramani, B.; Puranik, V.D.; Apte, S.K.; Gour, H.N.; Sharma, S.K.; Sharma, L.L.; Sharma, B.K.; Gupta, H.C.L.; Verma, P.C.

2007-01-01

The present symposium NSL addresses both the basic and applied aspects of limnology. The outcome of the symposium will help in the formulation of water policy that will result in the sustained availability of healthy fresh water resources and also benefit the industrial end user. Papers relevant to INIS are indexed separately

Proceedings of the international symposium on radiation vulcanization of natural rubber latex

International Nuclear Information System (INIS)

Machi, Sueo

1990-01-01

The First International Symposium on Radiation Vulcanization of Natural Rubber Latex (RVNRL) was held from 26 to 28 July 1989 at Tokyo and Takasaki. In these proceedings, thirty six papers presented at the Symposium are compiled. Main topics are commercial application of RVNRL, characterization of NR latex and vulcanization, properties of radiation vulcanized NR latex, development of sensitizers, mechanism of RVNRL, RVNRL with electron beams, and new Co-60 irradiator for RVNRL. Absence of nitrosamines and low cytotoxicity of radiation vulcanized NR latex are recognized as the remarkable advantages of RVNRL. The radiation vulcanization process for the production of protective rubber gloves for radioactive contamination was presented as the first commercial success in RVNRL. It was reported that various kinds of rubber articles for medical uses have being developed in West Germany. A sensitizer system consisting of n-butyl acrylate and t-butyl hydroperoxide was found to reduce the vulcanization dose to 8 kGy. (author)

International RILEM Symposium

CERN Document Server

Birgisson, Björn; Frost, David; Wang, Linbing

2013-01-01

The micro- and nano-modification of infrastructure materials and the associated multi-scale characterization and simulation has the potential to open up whole new uses and classes of materials, with wide-ranging implications for society. The use of multi-scale characterization and simulation brings the ability to target changes at the very small scale that predictably effect the bulk behavior of the material and thus allowing for the optimization of material behavior and performance.   The International RILEM Symposium on Multi-Scale Modeling and Characterization of Infrastructure Materials (Stockholm, June 10-12, 2013) brought together key researchers from around the world to present their findings and ongoing research in this field in a focused environment with extended discussion times. From asphalt to concrete, from chemistry to mechanics, from nano- to macro-scale: the collection of topics covered by the Symposium represents the width and depth of the currently ongoing efforts of developing more sustain...

Activation of 125I-Factor IX and 125I-Factor X: Effect of tissue factor and Factor VII, Factor Xsub(a) and thrombin

International Nuclear Information System (INIS)

Oesterud, B.; Rapaport, S.I.

Activation of Factor IX and Factor X was studied by adding 125 I-Factor IX or 125 I-Factor X to reaction mixtures and quantitating cleavage products by reduced sodium dodecylsulfate gel electrophoresis. Thrombin failed to activate Factors IX or X; Factor Xsub(a) produced insignificant amounts of cleavage products of both factors. In contrast, the reaction product of tissue factor and Factor VII cleaved large amounts of both Factor IX and Factor X in purified systems and in plasma. In incubation mixtures of plasma containing added 125 I-Factor IX or 125 I-Factor X, tissue factor and Ca 2+ ions, the percentage of total radioactivity in the heavy chain peak of 125 I-IXsub(a) and the heavy chain of 125 I-Xsub(a) increased at a similar rate. When the tissue factor was diluted, similar curves were obtained for percent cleavage of 125 I-Factor IX and percent cleavage of 125 I-Factor X plotted against tissue factor concentration. These findings support the hypothesis that activation of Factor IX by the tissue factor-Factor VII reaction product represents a physiologically significant step in normal haemostasis. (author)

International symposium on the history of mining and metallurgy. Internationales Symposium zur Geschichte des Bergbaus und Huettenwesens

Energy Technology Data Exchange (ETDEWEB)

Waechtler, E; Engewald, G R [eds.

1980-01-01

The VII. International Symposium took place in Freiberg and Reinsberg, in the German Democratic Republic, from September 4-8, 1978. The Symposium was organized by the Executive Committee of the International Committee on the History of Technology (ICOHTEC) and was attended by 77 participants from 14 countries in Eastern and Western Europe as well as USA and Canada. A total of 51 papers were published and 30 talks were held and analyzed in discussions. The papers dealt with selected topics on the history of the mining and metallurgical industries, primarily from the fifteenth century to the twentieth century. The topics concern the development of science, of new mining and metallurgical equipment and processes, innovation in mines, increase in productivity, improvement in working conditions, economic progress and economic crisis, social aspects of the labor force and trade union movements in major mining countries. An excursion to a brown coal surface mine was organized in conjunction with the Symposium. (In German)

Growth stimulation of Porphyromonas endodontalis by hemoglobin and protoporphyrin IX.

Science.gov (United States)

Zerr, M A; Cox, C D; Johnson, W T; Drake, D R

2000-12-01

Porphyromonas endodontalis, like other Porphyromonas species, has a complex set of nutritional requirements. In addition to being an obligate anaerobe, the bacterium must be grown in a complex medium consisting of amino acids, reducing agents and heme compounds. P. endodontalis accumulates high concentrations of heme pigments to the extent that colonies appear black on blood agar. This accumulation of heme and the need for these compounds has been characterized as iron requirements by these species. However, in our studies, P. endodontalis demonstrated growth dependence on hemoglobin or protoporphyrin IX but not on free iron. Iron added to other heme compounds actually decreased growth stimulation by porphyrin-containing compounds. P. endodontalis actively transported free iron, but this process did not appear to be critical for growth. The maximum stimulation of growth by protoporphyrin IX, under conditions of iron deprivation, suggests that P. endodontalis requires the porphyrin moiety as a growth factor.

Motives and periods in Bianchi IX gravity models

Science.gov (United States)

Fan, Wentao; Fathizadeh, Farzad; Marcolli, Matilde

2018-05-01

We show that, when considering the anisotropic scaling factors and their derivatives as affine variables, the coefficients of the heat-kernel expansion of the Dirac-Laplacian on SU(2) Bianchi IX metrics are algebro-geometric periods of motives of complements in affine spaces of unions of quadrics and hyperplanes. We show that the motives are mixed Tate and we provide an explicit computation of their Grothendieck classes.

Mining and Reclamation Technology Symposium

Energy Technology Data Exchange (ETDEWEB)

None Available

1999-06-24

The Mining and Reclamation Technology Symposium was commissioned by the Mountaintop Removal Mining/Valley Fill Environmental Impact Statement (EIS) Interagency Steering Committee as an educational forum for the members of the regulatory community who will participate in the development of the EIS. The Steering Committee sought a balanced audience to ensure the input to the regulatory community reflected the range of perspectives on this complicated and emotional issue. The focus of this symposium is on mining and reclamation technology alternatives, which is one of eleven topics scheduled for review to support development of the EIS. Others include hydrologic, environmental, ecological, and socio-economic issues.

Proceedings of the 3rd NINS symposium on engineering and technology

International Nuclear Information System (INIS)

2008-10-01

The 3rd NINS Symposium on Engineering and Technology was held on 24-25, July 2008 at National Institute for Fusion Science (NIFS), organized by Department of Engineering and Technical Services, NIFS. This Symposium is continuation of an annual series. The 1st one was held on 25-26 July, 2006 organized by National Astronomical Observatory of Japan. The 2nd one was held on 25-26 June, 2007 organized by Institute for Molecular Science. This proceedings is a compilation of papers presented at the symposium. 49 participants from 5 institutes of NINS attended this symposium and 23 papers were presented. (author)

In vitro evaluation of photodynamic therapy using redox-responsive nanoparticles carrying PpIX

Science.gov (United States)

Souza Leite, Ilaiáli; Vivero-Escoto, Juan L.; Lyles, Zachary; Salvador Bagnato, Vanderlei; Mayumi Inada, Natalia

2018-02-01

Photodynamic therapy (PDT) is a technique that combines light's interaction with a photoactive substance to promote cellular death and that has been used to treat a wide range of maladies. Cancer is among the leading causes of death worldwide and has been a central issue assessed by PDT research and clinical trials over the last 35 years, but its efficiency has been hampered by photosensitizer buildup at treatment site. Nanotechnology has been addressing drug delivery problems by the development of distinct nanostructured platforms capable of increasing pharmacological properties of molecules. The association of nanotechnology's potential to enhance photosensitizer delivery to target tissues with PDT's oxidative damage to induce cell death has been rising as a prospect to optimize cancer treatment. In this study, we aim to verify and compare the efficiency of PDT using redox-responsive silica-based nanoparticles carrying protoporphyrin IX (PpIX) in vitro, in both tumor and healthy cells. Dose-response experiments revealed the higher susceptibility of murine melanoma cells (B16-F10 cell line) to PDT (630 nm, 50 J/cm2) when compared to human dermal fibroblasts (HDFn): after 24 h of incubation with 50 μg/mL nanoparticles solutions, approximately 80 % of B16- F10 cells were killed, while similar results were obtained in HDFn cultures when solutions over 150 μg/mL were used. Uptake and ROS generation assays suggest increased nanoparticle internalization in the tumor cell line, in comparison with the healthy cells, and greater ROS levels were observed in B16-F10 cells.

Kasseler symposium on energy-related system engineering: renewable energy sources and rational energy use. Proceedings '98; Kasseler Symposium Energie-Systemtechnik: Erneuerbare Energien und Rationelle Energieverwendung. Tagungsband '98

Energy Technology Data Exchange (ETDEWEB)

Schwarz, R. [comp.

1999-07-01

The ISET ended the 10th anniversary year since its foundation in 1998 with already the third Kassel symposium on energy-related system engineering: renewable energy sources and rational energy use. Covering several special subjects talks were given about the topics modelling and simulation in the fields of wind energy, photovoltaic systems, hybrid systems or sewage water treatment. The keen interest of the participants shows the importance that modelling of conditions or processes has gained in the meantime in the field of system engineering of renewable energy sources. The core of each simulation is the integration of differential equations, which describe the system. Properties of the system can be easily varied and affects on the overall system can be easily investigated. Critical conditions can be discovered and be taken into consideration at the hardware engineering. Mistakes in terms of component design can be avoided and engineering cost can be reduced considerably. The present conference book gives an ideal overview of the topics discussed during the symposium. (orig.) [German] Sein Jubilaeumsjahr zum zehnjaehrigen Bestehen beschloss das ISET 1998 mit dem nun bereits 3. Kasseler Symposium Energie-Systemtechnik - Erneuerbare Energien und Rationelle Energieverwendung. Fachgebietsuebergreifend wurde zu den Themen Modellbildung und Simulation in Bereichen wie Windenergie, Photovoltaik, Hybridsysteme oder Abwasserbehandlung referiert. Das rege Interesse der Teilnehmer unterstreicht die Bedeutung, die die Modellierung von Zustaenden oder Prozessen in der Systementwicklung bei den erneuerbaren Energien inzwischen gewonnen hat. Der Kern einer jeden Simulation ist die Integration der systembeschreibenden Differentialgleichungen. Eigenschaften des Systems koennen in einfacher Weise variiert und die Auswirkungen auf das Gesamtsystem untersucht werden. Kritische Zustaende koennen entdeckt und in der Entwicklung der Hardware entsprechend beruecksichtigt werden. Fehler

International Symposium for the Promotion of APEC Environmental Technology Exchange; APEC kankyo gijutsu koryu sokushin symposium

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-11-11

The International Symposium for the Promotion of APEC Environmental Technology Exchange was held under the theme `The function and role expected of the APEC Virtual Center,` with the objectives of clarifying the need for future intra-regional environmental technological exchange, defining the types of information and personnel exchange, and promoting the use of interactive character of the APEC Virtual Center for Environmental Technology Exchange by encouraging access to and participation in the Virtual Center project. It was held in the period of 11th and 12th, November in 1996, at the venue of Rinku International Convention Center in Osaka. The symposium was attended by 477 persons from nine countries, i.e., Australia, Canada, China, Indonesia, Korea, Philippines, Thailand, the US, and Japan, comprising staff members of intra-regional environment-related organizations. After the keynote speech, `Current status and tasks of environmental technology exchange`, and `Expected roles of the Virtual Center for Environmental Technology Exchange` were discussed. During the plenary session, the chairman summarized the symposium. This summary was carried on the Virtual Center homepage of the Internet

Immunosuppressive effects of factor IX products: an in vitro study.

Science.gov (United States)

Grosset, A B; McGregor, J R; Samlowski, W E; Rodgers, G M

1999-11-01

The effects of a recombinant factor IX product (BeneFix), and of five plasma-derived factor IX products, AlphaNine, Immunine, Konyne, Mononine and Replinine on in vitro peripheral blood mononuclear cell (PBMC) immune function were compared in a blinded study. We assessed the effects of these products on Con-A-induced lymphocyte proliferation and interleukin-2 and interleukin-10 secretion, expression of lymphocyte activation markers, and nitric oxide secretion by stimulated mouse peritoneal macrophages. At 1 mL-1 for 48 h, Konyne reduced Con-A-induced mitogenesis by 50% (P < 0.05); AlphaNine, Mononine and BeneFix had no effect. At 10 IU mL-1, Con-A-induced mi- togenesis was at control levels with Mononine and BeneFix, but was reduced to <15% (P < 0.05) with each of the other products. IL-2 and IL-10 secretion by Con-A-stimulated lymphocytes was also markedly depressed by all the products tested except Mononine and BeneFix. Dialysis of these products did not substantially affect these results. Flow cytometric analysis of lymphocyte activation markers following Con-A stimulation showed that Konyne also decreased IL-2 receptor alpha and beta chain (CD25 and CD122) induction on PBMC. Konyne also inhibited nitric oxide secretion to levels <18% of controls. These results indicate that certain factor IX products, including some of purported higher purity, substantially depress in vitro immune function. The importance of these findings to in vivo immune function in haemophilia B patients remains to be established.

Ares I-X Flight Test Philosophy

Science.gov (United States)

Davis, S. R.; Tuma, M. L.; Heitzman, K.

2007-01-01

In response to the Vision for Space Exploration, the National Aeronautics and Space Administration (NASA) has defined a new space exploration architecture to return humans to the Moon and prepare for human exploration of Mars. One of the first new developments will be the Ares I Crew Launch Vehicle (CLV), which will carry the Orion Crew Exploration Vehicle (CEV), into Low Earth Orbit (LEO) to support International Space Station (ISS) missions and, later, support lunar missions. As part of Ares I development, NASA will perform a series of Ares I flight tests. The tests will provide data that will inform the engineering and design process and verify the flight hardware and software. The data gained from the flight tests will be used to certify the new Ares/Orion vehicle for human space flight. The primary objectives of this first flight test (Ares I-X) are the following: Demonstrate control of a dynamically similar integrated Ares CLV/Orion CEV using Ares CLV ascent control algorithms; Perform an in-flight separation/staging event between an Ares I-similar First Stage and a representative Upper Stage; Demonstrate assembly and recovery of a new Ares CLV-like First Stage element at Kennedy Space Center (KSC); Demonstrate First Stage separation sequencing, and quantify First Stage atmospheric entry dynamics and parachute performance; and Characterize the magnitude of the integrated vehicle roll torque throughout the First Stage (powered) flight. This paper will provide an overview of the Ares I-X flight test process and details of the individual flight tests.

Army symposium: Electrical energy engineering today; Wehrtechnisches Symposium: Moderne elektrische Energietechnik

Energy Technology Data Exchange (ETDEWEB)

Busse, H. (ed.) [Bundesakademie fuer Wehrverwaltung und Wehrtechnik, Mannheim (Germany). Fachgebiet Elektrotechnik und Elektroenergiewesen

2000-05-01

This symposium was held in Mannheim on May 20/21, 2000. All aspects of energy engineering were discussed, including electrochemical energy sources like accumulator batteries and fuel cells. The proceedings volume contains 26 papers which reflect the state of the art and current trends in electrical energy engineering in the German army. [German] Das Wehrtechnische Symposium 'Moderne elektrische Energietechnik' wurde von der Lehrabteilung Wehrtechnik der Bundesakademie fuer Wehrverwaltung und Wehrtechnik in Mannheim in der Zeit vom 20.05.-21.05.2000 durchgefuehrt. Das Programm enthaelt die aktuellen Themen der elektrischen Energietechnik. Die elektroschemischen Energiequellen (Batterien und Brennstoffzellen) wurden in das Programm integriert. Dadurch konnte das gesamte Spektrum der Energietechnik vielschichtig dargestellt und in der Diskussion unter z.T. sehr verschiedenen Gesichtspunkten beleuchtet werden. Die im vorliegenden Tagungsband abgedruckten 26 Skripte wurden weder gekuerzt noch ergaenzt. Sie zeigen insgesamt den aktuellen Stand und die erfolgversprechenden Entwicklungstendenzen der elektrischen Energietechnik in der Bundeswehr auf. (orig.)

77 FR 4568 - Annual Computational Science Symposium; Public Conference

Science.gov (United States)

2012-01-30

...] Annual Computational Science Symposium; Public Conference AGENCY: Food and Drug Administration, HHS... with the Pharmaceutical Users Software Exchange (PhUSE), is announcing a public conference entitled ``The FDA/PhUSE Annual Computational Science Symposium.'' The purpose of the conference is to help the...

Dynamic of exact perturbations in Bianchi IX type cosmological models

International Nuclear Information System (INIS)

Mello Neto, J.R.T. de.

1985-01-01

The dynamic of Bianchi IX type cosmological models is studied, after reducing Einstein equations to Hamiltonian system. Using the Melnikov method, the existence of chaos in the dynamic of these models is proved, and some numerical experiments are carried out. (M.C.K.) [pt

International Ocean Symposium (IOS) 1996; Kokusai kaiyo symposium 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-02-18

This is a proceedings of the International Ocean Symposium 1996. On the first day of the symposium, the following were given with a theme `The Ocean, Can She Save Us`: Underwater research and future of mankind as a commemorative speech; The ocean, can she save us -- trying to discover the true figure of the ocean as a keynote speech. Panel discussion was held on The global environment and the infinite potential of the ocean. On the second day, an approach was made mostly from a cultural aspect with a theme `The Ocean and the Japanese.` The following were given: Human links between east and west as a commemorative speech; The ocean and Japanese culture as a keynote speech; Civilization spanning across oceans as a panel discussion. The Japanese have been developing their individual technologies in shipbuilding, shipping, and ocean development, have been raised by Mother Ocean, and have lived together. Ocean has been supplying humans food, water, oxygen, marine routes, and even dream and hope. The environmental pollution is the result of the human greediness. It is fear and friendship between humans and ocean that can save humans and ocean.

28th International Symposium on Shock Waves

CERN Document Server

2012-01-01

The University of Manchester hosted the 28th International Symposium on Shock Waves between 17 and 22 July 2011. The International Symposium on Shock Waves first took place in 1957 in Boston and has since become an internationally acclaimed series of meetings for the wider Shock Wave Community. The ISSW28 focused on the following areas: Blast Waves, Chemically Reacting Flows, Dense Gases and Rarefied Flows, Detonation and Combustion, Diagnostics, Facilities, Flow Visualisation, Hypersonic Flow, Ignition, Impact and Compaction, Multiphase Flow, Nozzle Flow, Numerical Methods, Propulsion, Richtmyer-Meshkov, Shockwave Boundary Layer Interaction, Shock Propagation and Reflection, Shock Vortex Interaction, Shockwave Phenomena and Applications, as well as Medical and Biological Applications. The two Volumes contain the papers presented at the symposium and serve as a reference for the participants of the ISSW 28 and individuals interested in these fields.

XXth symposium neuroradiologicum 2014

Energy Technology Data Exchange (ETDEWEB)

NONE

2014-09-15

The volume includes abstracts from lectures and poster presentations during the XXth symposium neuroradiologicum 2014 covering the following issues: Stroke, head and neck, pediatric diagnostic neuroradiology, spine and interventional neuroradiology, adult diagnostic neuroradiology, intravascular interventional neuroradiology.

Proceedings of the sixteenth biennial low-rank fuels symposium

International Nuclear Information System (INIS)

1991-01-01

Low-rank coals represent a major energy resource for the world. The Low-Rank Fuels Symposium, building on the traditions established by the Lignite Symposium, focuses on the key opportunities for this resource. This conference offers a forum for leaders from industry, government, and academia to gather to share current information on the opportunities represented by low-rank coals. In the United States and throughout the world, the utility industry is the primary user of low-rank coals. As such, current experiences and future opportunities for new technologies in this industry were the primary focuses of the symposium

Proceedings of the first internet symposium on nuclear data

International Nuclear Information System (INIS)

Fukahori, Tokio; Iwamoto, Osamu; Nakagawa, Tsuneo

1997-03-01

The First Internet Symposium on Nuclear Data (ISND-1) was held on the WWW home page of Nuclear Data Center at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), from April 8 to June 15, 1996. This symposium was organized by Japanese Nuclear Data Committee and Nuclear Data Center, JAERI and was the first trial to use 'Internet' for the symposium in a nuclear data field. In ISND-1, presented were 25 papers on various topics of nuclear data. Those presented papers are compiled in this proceedings as well as brief description about management of ISND-1. (author)

Proceedings of the first internet symposium on nuclear data

Energy Technology Data Exchange (ETDEWEB)

Fukahori, Tokio; Iwamoto, Osamu; Nakagawa, Tsuneo [eds.] [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1997-03-01

The First Internet Symposium on Nuclear Data (ISND-1) was held on the WWW home page of Nuclear Data Center at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), from April 8 to June 15, 1996. This symposium was organized by Japanese Nuclear Data Committee and Nuclear Data Center, JAERI and was the first trial to use `Internet` for the symposium in a nuclear data field. In ISND-1, presented were 25 papers on various topics of nuclear data. Those presented papers are compiled in this proceedings as well as brief description about management of ISND-1. (author)

Proceedings of the 3rd Symposium on Engineering Sciences

International Nuclear Information System (INIS)

Ahmed, J.; Rizvi, S.Z.H.; Ahmad, R.; Saleem, M.

2010-01-01

The 3rd symposium on engineering sciences was held from March 10-12, 2010 in Lahore, Pakistan. More than twenty academic institutions and six industries participated in this conference. The foreign and Pakistani experts delivered their keynotes talk, contributor lectures and poster presentation on the conference topics. In three days of the symposium, Fifty four papers presented on different topics of Engineering Sciences including chemical engineering, energy engineering, metallurgy engineering, material engineering and electrical engineering. This symposium provided an ideal opportunity for exchange of information amongst scientists, engineers and researchers from all over Pakistan and other countries of the world. (A.B)

Proceedings of the sixteenth biennial low-rank fuels symposium

Energy Technology Data Exchange (ETDEWEB)

1991-01-01

Low-rank coals represent a major energy resource for the world. The Low-Rank Fuels Symposium, building on the traditions established by the Lignite Symposium, focuses on the key opportunities for this resource. This conference offers a forum for leaders from industry, government, and academia to gather to share current information on the opportunities represented by low-rank coals. In the United States and throughout the world, the utility industry is the primary user of low-rank coals. As such, current experiences and future opportunities for new technologies in this industry were the primary focuses of the symposium.

PREFACE: XXXV Symposium on Nuclear Physics

Science.gov (United States)

Padilla-Rodal, E.; Bijker, R.

2012-09-01

Conference logo The XXXV Symposium on Nuclear Physics was held at Hotel Hacienda Cocoyoc, Morelos, Mexico from January 3-6 2012. Conceived in 1978 as a small meeting, over the years and thanks to the efforts of various organizing committees, the symposium has become a well known international conference on nuclear physics. To the best of our knowledge, the Mexican Symposium on Nuclear Physics represents the conference series with longest tradition in Latin America and one of the longest-running annual nuclear physics conferences in the world. The Symposium brings together leading scientists from all around the world, working in the fields of nuclear structure, nuclear reactions, physics with radioactive ion beams, hadronic physics, nuclear astrophysics, neutron physics and relativistic heavy-ion physics. Its main goal is to provide a relaxed environment where the exchange of ideas, discussion of new results and consolidation of scientific collaboration are encouraged. To celebrate the 35th edition of the symposium 53 colleagues attended from diverse countries including: Argentina, Australia, Canada, Japan, Saudi Arabia and USA. We were happy to have the active participation of Eli F Aguilera, Eduardo Andrade, Octavio Castaños, Alfonso Mondragón, Stuart Pittel and Andrés Sandoval who also participated in the first edition of the Symposium back in 1978. We were joined by old friends of Cocoyoc (Stuart Pittel, Osvaldo Civitarese, Piet Van Isacker, Jerry Draayer and Alfredo Galindo-Uribarri) as well as several first time visitors that we hope will come back to this scientific meeting in the forthcoming years. The scientific program consisted of 33 invited talks, proposed by the international advisory committee, which nicely covered the topics of the Symposium giving a balanced perspective between the experimental and the theoretical work that is currently underway in each line of research. Fifteen posters complemented the scientific sessions giving the opportunity

Proceedings of the international symposium on materials testing reactors

International Nuclear Information System (INIS)

Ishihara, Masahiro; Kawamura, Hiroshi

2009-01-01

This report is the Proceedings of the International Symposium on Materials Testing Reactors hosted by Japan Atomic Energy Agency (JAEA). The symposium was held on July 16 to 17, 2008, at the Oarai Research and Development Center of JAEA. This symposium was also held for the 40th anniversary ceremony of Japan Materials Testing Reactor (JMTR) from achieving its first criticality. The objective of the symposium is to exchange the information on current status, future plan and so on among each testing reactors for the purpose of mutual understanding. There were 138 participants from Argentina, Belgium, France, Indonesia, Kazakhstan, Korea, the Russian Federation, Sweden, the United State, Vietnam and Japan. The symposium was divided into four technical sessions and three topical sessions. Technical sessions addressed the general topics of 'status and future plan of materials testing reactors', 'material development for research and testing reactors', irradiation technology (including PIE technology)' and 'utilization with materials testing reactors', and 21 presentations were made. Also the topical sessions addressed 'establishment of strategic partnership', 'management on re-operation work at reactor trouble' and 'basic technology for neutron irradiation tests in MTRs', and panel discussion was made. The 21 of the presented papers are indexed individually. (J.P.N.)

Reaching the hip-hop generation: Final (symposium proceedings) report

Energy Technology Data Exchange (ETDEWEB)

1993-05-01

The goal of this final (closing) report is to capture the flavor of the symposium held March 1 and 2, 1993 in New York City convened by Motivational Educational Entertainment, Inc. (MEE), a black-owned communications research, consulting, and video production company based in Philadelphia, Pennsylvania. The mission of MEE is to understand, reach, and positively affect inner-city youth. Traditional communication approaches from mainstream sources to at-risk youth often don`t account for the unique way youth communicate among themselves and how they relate to the media. This understanding, however, is crucial. To understand youth communication, the people who create and send both entertaining and educational messages to urban youth must be brought into the dialogue. The meeting in New York was intended to provide an important opportunity for senders to meet and evaluate the appropriateness and effectiveness of their messages. In addition, the MEE symposium provided a forum for the continuing public debate about what needs to be done to reach today`s urban teens. Included in this document is a description of symposium goals/objectives, symposium activities, the reaction to and analysis of the symposium, recommendations for future MEE courses of action, and an appendix containing copies of press articles.

Improving contrast enhancement in magnetic resonance imaging using 5-aminolevulinic acid-induced protoporphyrin IX for high-grade gliomas.

Science.gov (United States)

Yamamoto, Junkoh; Kakeda, Shingo; Yoneda, Tetsuya; Ogura, Shun-Ichiro; Shimajiri, Shohei; Tanaka, Tohru; Korogi, Yukunori; Nishizawa, Shigeru

2017-03-01

Magnetic resonance imaging (MRI) with a gadolinium-based contrast agent is the gold standard for high-grade gliomas (HGGs). The compound 5-aminolevulinic acid (5-ALA) undergoes a high rate of cellular uptake, particularly in cancer cells. In addition, fluorescence-guided resection with 5-ALA is widely used for imaging HGGs. 5-ALA is water soluble, while protoporphyrin IX (PpIX) is water insoluble. It was speculated whether converting from 5-ALA to PpIX may relatively increase intracellular water content, and consequently, might enhance the T2 signal intensity in HGG. The aim of the present study was to assess whether 5-ALA-induced PpIX enhances the T2 signal intensity in patients with HGGs. A total of 4 patients who were candidates for HGG surgical treatment were prospectively analyzed with preoperative MRI. Patients received oral doses of 5-ALA (20 mg/kg) 3 h prior to anesthesia. At 2.5 h post-5-ALA administration, T2-weighted images (T2WIs) were obtained from all patients. Subsequently, tumors were evaluated via fluorescence using a modified operating microscope. Fluorescent tumor tissues were obtained to analyze the accumulation of 5-ALA-induced PpIX within the tumors, which was confirmed quantitatively by high-performance liquid chromatography (HPLC) analysis. The MRI T2 signal intensity within the tumors was evaluated prior to and following 5-ALA administration. Three glioblastoma multiformes (GBMs) and 1 anaplastic oligodendroglioma (AO) were included in the analysis. Intraoperatively, all GBMs exhibited strong fluorescence of 5-ALA-induced PpIX, whilst no fluorescence was observed in the AO sample. HPLC analysis indicated a higher accumulation of 5-ALA-induced PpIX in the GBM samples compared with the AO sample. In total, 48 regions of interest were identified within the tumors from T2-WIs. In the GBM group, the relative T2 signal intensity value within the tumors following 5-ALA administration was significantly increased compared with the T2 signal

1st Jagiellonian Symposium on Fundamental and Applied Subatomic Physics

CERN Document Server

2016-01-01

Following the success of two meetings "II Symposium on applied nuclear physics and innovative technologies" and "II Symposium on Positron Emission Tomography" organized in 2014, this event will start a new series of conferences which will bring together scientists from the physics, nuclear medicine and healthcare. One of the main purposes of the symposium is to exchange experience and and expertise gained by various institutions in the field of applied and fundamental nuclear as well as particle physics, medical imaging, radiotherapy and healthcare.

Analysis of transcriptional isoforms of collagen types IX, II, and I in the developing avian cornea by competitive polymerase chain reaction.

Science.gov (United States)

Fitch, J M; Gordon, M K; Gibney, E P; Linsenmayer, T F

1995-01-01

The genes for the alpha 1(IX), alpha 1(II), and alpha 2(I) collagen chains can give rise to different isoforms of mRNA, generated by alternative promotor usage [for alpha 1(IX) and alpha 2(I)] or alternative splicing [for alpha 1(II)]. In this study, we employed competitive reverse transcriptase PCR to quantitate the amounts of transcriptional isoforms for these genes in the embryonic avian cornea from its inception (about 3 1/2 days of development) to 11 days. In order to compare values at different time points, the results were normalized to those obtained for the "housekeeping" enzyme, glycerol-3-phosphate dehydrogenase (G3PDH). These values were compared to those obtained from other tissues (anterior optic cup and cartilage) that synthesize different combinations of the collagen isoforms. We found that, in the cornea, transcripts from the upstream promotor of alpha 1(IX) collagen (termed "long IX") were predominant at stage 18-20 (about 3 1/2 days), but then fell rapidly, and remained at a low level. By 5 days (just before stromal swelling) the major mRNA isoform of alpha 1(IX) was from the downstream promoter (termed "short IX"). The relative amount of transcript for the short form of type IX collagen rose to a peak at about 6 days of development, and then declined. Throughout this period, the predominant transcriptional isoform of the collagen type II gene was IIA (i.e., containing the alternatively spliced exon 2). This indicates that the molecules of type II collagen that are assembled into heterotypic fibrils with type I collagen possess, at least transiently, an amino-terminal globular domain similar to that found in collagen types I, III, and V. For type I, the "bone/tendon" mRNA isoform of the alpha 2(I) collagen gene was predominant; transcripts from the downstream promotor were at basal levels. In other tissues expressing collagen types IX and II, long IX was expressed predominantly with the IIA form in the anterior optic cup at stage 22/23; in 14 1

Proceedings of the sixty-sixth annual session of Indian Institute of Chemical Engineers and joint Indo-North American symposium: oral and poster abstracts

International Nuclear Information System (INIS)

2013-01-01

The aim of the symposium was to to discuss the current trends and future developments in the field of chemical engineering technology. The main themes of the symposium were: Advanced Separation Techniques; Biochemical Engineering; Process Intensification; Fossil Fuel, Nuclear and Alternate Energy; Novel Reactors and operating strategies; Green Chemistry and Engineering; Food Security; Water Treatment, Reuse and Recycle; Healthcare Technology; Nanomaterials; Process Development; Process Engineering and Control; Borderless Chemical Engineering; Fluid Mechanics and CFD; Intellectual Property Rights; Sustainable Development etc. Papers relevant to INIS are indexed separately

Nuclear science symposium, 26th and symposium on nuclear power systems, 11th, 1979

International Nuclear Information System (INIS)

Kerns, C.R.

1980-01-01

Proceedings include 163 of the papers presented at the combined meetings, as well as two papers delivered at the plenary session on plant control beyond the 1980's and ionizing radiation dose hazards. One-hundred-and-sixty-two papers are indexed separately. Nuclear Science symposium included calorimeters and specific ionization (17 papers); PWC and Drift Chambers (7 papers); photo/optical detectors (10 papers); semiconductor detectors (11 papers); nuclear circuits and systems (11 papers); space instrumentation (9 papers); medical instrumentation (30 papers); data preprocessing (6 papers); data acquisition (11 papers); environmental instrumentation (15 papers); reactor instrumentation (16 papers). Fifteen Nuclear Systems Symposium papers covered: safety, RFI effects, detectors, monitoring systems, reactor protection, multiplexing of circuits, standard application, emergency planning and preparedness and operator/instrumentation interactions

International Symposium for Thyroid Eye Disease (June 2016, London

Directory of Open Access Journals (Sweden)

Natalia Y. Sviridenko

2017-03-01

Full Text Available In June 2016, an International Symposium dedicated to the cutting edge research and achievements in Thyroid Eye Disease (TED diagnosis and treatment was held in London. The symposium was organized by the International Thyroid Eye Disease (ITEDs. It was attended EUGOGO, North American Neuro-Ophthalmological Society (NANOS and Orbit Society members. The symposium was attended by leading experts in the field of ophthalmology, orbital surgery and endocrinology: Rebecca S. Bahn, Maarten Mourits, Claudio Marcocci, George Kahaly, Mario Salvi, Antony Weetman, Anja Eckstein, Daniel Rootman, Geoffrey Rose, Robert Goldberg and Susanne Pitz, as well as doctors, specializing in the field of endocrinology, ophthalmology, radiology and other specialties. The symposium program was focused on the discussion of TED pathogenesis, classification and new therapeutic and surgical approaches. TED problems discussed by more than 300 professionals (65% ophthalmologists, 18% ophthalmic surgeons and 17% endocrinologists. North America was represented by 50 delegates. Representation of other continents was not less impressive.

9th International Frumkin symposium: Electrochemical technologies and materials for 21st century. Abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-07-01

Abstracts of the 9th International Frumkin symposium: Electrochemical technologies and materials for 21st century are presented. The symposium was held 24-29 October 2010 in Moscow. The symposium included the following microsymposiums: Electrical double layer and electrochemical kinetics (from phenomenological to molecular level); New processes, materials and devices for successful electrochemical transformation of energy; Corrosion and protection of materials; General and local corrosion; Electroactive composition materials; Bioelectrochemistry. The Frumkin symposium includes plenary lectures, oral and poster presentations. Official language of the symposium is English

9th International Frumkin symposium: Electrochemical technologies and materials for 21st century. Abstracts

International Nuclear Information System (INIS)

2010-01-01

Abstracts of the 9th International Frumkin symposium: Electrochemical technologies and materials for 21st century are presented. The symposium was held 24-29 October 2010 in Moscow. The symposium included the following microsymposiums: Electrical double layer and electrochemical kinetics (from phenomenological to molecular level); New processes, materials and devices for successful electrochemical transformation of energy; Corrosion and protection of materials; General and local corrosion; Electroactive composition materials; Bioelectrochemistry. The Frumkin symposium includes plenary lectures, oral and poster presentations. Official language of the symposium is English [ru

Memorial Symposium for Victor Weisskopf

CERN Multimedia

2002-01-01

Victor 'Viki' Weisskopf, former Director General of CERN from 1961 to 1965, passed away five months ago. At that time, the Bulletin dedicated its coverpage to this brilliant physicist (19-20/2002). Now, CERN has organised a Memorial Symposium for next Tuesday 17 September, where you are cordially invited. This tribute will include the following speechs: L. Maiani: Welcome J. D. Jackson: Highlights from the career and scientific works of Victor F. Weisskopf M. Hine and K. Johnsen: Working with Viki at CERN M. Jacob: Knowledge and Wonder A member of Viki's family: Reminiscences. The Memorial Symposium will take place in the Main Auditorium at 15h. Drinks will be served in Pas Perdus at 17h 30.

Proceedings of the 2011 symposium on nuclear data

International Nuclear Information System (INIS)

Harada, Hideo; Yokoyama, Kenji; Iwamoto, Nobuyuki; Nakamura, Shoji

2012-12-01

The 2011 data symposium on nuclear data, organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) was held at Ricotti, Tokai, on Nov. 16 and 17, 2011 in cooperation with Nuclear Science and Engineering Directorate of JAEA and North-Kanto Branch of AESJ. The symposium was devoted for discussions and presentations of current topics in the field of nuclear data such as nuclear accident and accident analysis code, innovative methods on nuclear data theory and measurements, and nuclear data applications, including 2 tutorial talks, NJOY99 and PHITS. Talks as well as posters presented at the symposium aroused lively discussions among 97 participants. This report contains 34 papers submitted from the oral and poster presenters. (author)

Symposium overview: alterations in cytokine receptors by xenobiotics.

Science.gov (United States)

Cohen, M D; Schook, L B; Oppenheim, J J; Freed, B M; Rodgers, K E

1999-04-01

A symposium entitled Alterations in Cytokine Receptors by Xenobiotics was held at the 37th Annual Meeting of the Society of Toxicology (SOT) in Seattle, Washington. The symposium was sponsored by the Immunotoxicology Specialty Section of SOT and was designed to present information on the effect of several different classes of xenobiotics on various aspects of receptor function (i.e., post-receptor signal transduction of receptor expression), or the involvement of cytokine receptors in the action of the toxicant under consideration. This symposium brought together scientists in the area of receptor immunobiology whose expertise in receptor modulation encompassed those major signaling agents involved in the normal immune response, i.e., proinflammatory cytokines, chemokines, interleukins, and interferons. The following is a summary of each of the individual presentations.

Proceedings of the 13th international symposium on laser-aided plasma diagnostics

International Nuclear Information System (INIS)

Kawahata, Kazuo

2007-09-01

The 9th international symposium on LASER-AIDED PLASMA DIAGNOSTICS was held from 18th November to 21st September, 2007 at Takayama, Japan. This symposium was organized by the National Institute for Fusion Science, Toki, Japan. The topics of the symposium include laser diagnostics and diagnostics aided by lasers for fusion plasmas, industrial process plasmas, environmental plasmas as well as for other plasma applications and processes related to plasmas. Hardware development related to laser-aided plasma diagnostics is another topic. Over 80 participants attended this international symposium. 1 Akazaki lecture, 10 general talks, 10 topical talks, 12 short oral talks and 45 posters were presented. This issue is the collection of the papers presented at the title symposium. The 41 of the presented papers are indexed individually. (J.P.N.)

22nd DAE High Energy Physics Symposium

CERN Document Server

2018-01-01

These proceedings gather invited and contributed talks presented at the XXII DAE-BRNS High Energy Physics (HEP) Symposium, which was held at the University of Delhi, India, on 12–16 December 2016. The contributions cover a variety of topics in particle physics, astroparticle physics, cosmology and related areas from both experimental and theoretical perspectives, namely (1) Neutrino Physics, (2) Standard Model Physics (including Electroweak, Flavour Physics), (3) Beyond Standard Model Physics, (4) Heavy Ion Physics & QCD (Quantum Chromodynamics), (5) Particle Astrophysics & Cosmology, (6) Future Experiments and Detector Development, (7) Formal Theory, and (8) Societal Applications: Medical Physics, Imaging, etc. The DAE-BRNS High Energy Physics Symposium, widely considered to be one of the leading symposiums in the field of Elementary Particle Physics, is held every other year in India and supported by the Board of Research in Nuclear Sciences (BRNS), Department of Atomic Energy (DAE), India. As man...

VIII All-Russian symposium on molecular liquid chromatography and capillary electrophoresis. Program. Summary of reports

International Nuclear Information System (INIS)

2001-01-01

Program and summary of reports of the VIII All-Russian symposium on molecular liquid chromatography and capillary electrophoresis are performed. The meeting took place 15-19 October, 2001 in Moscow. Many problems of liquid and ion exchange chromatography, capillary electrophoresis, thin-layer chromatography have been discussed extensively. Reports covering properties of sorbents and devices for chromatography are incorporated in the collection [ru

IX Congress of Spanish radiation protection Society (Bilbao, May-2002)

International Nuclear Information System (INIS)

2002-01-01

The present book contains the papers presented to the IX Congress of Spanish Radiation Protection Society. The main sessions were : 1.- Scientific area of Radiation Protection and Regulation, Social aspects, Radioactive waste management and Dismantling. 2.- Radiation protection in Medical applications. 3.- Physics of radiations and their measurements

Proceedings of the third Asian symposium on materials and processing: souvenir

International Nuclear Information System (INIS)

2012-01-01

Materials characterization and measurement techniques, materials processing, forming, casting and machining, mechanical properties, fracture and reliability, metals, ceramics, polymers and composites, modeling, analysis and simulation in materials and processing, nano fabrication and nano/micro/meso manufacturing processes and advanced manufacturing, non-destructive testing and evaluations, monitoring and sensing technology, powder metallurgy, adhesion and interface, welding and bonding, smart materials and structures, functional materials, surface engineering and thin films and coatings are the topics covered in this symposium. Papers relevant to INIS are indexed separately

Preface [21. international school on nuclear physics and applications; ISEN-2015: International symposium on exotic nuclei, Varna (Bulgaria), 6-12 September 2015

International Nuclear Information System (INIS)

2016-01-01

The present volume contains the lectures and short talks given at the XXI International School on Nuclear Physics and Applications and International Symposium on Exotic Nuclei (ISEN-2015). The School and the Symposium were held from 6-12 September 2015 in “Club Hotel Bolero” located in ‘Golden Sands’ (Zlatni Pyasaci) Resort on the Black Sea coast, near Varna, Bulgaria. The School and the Symposium were organized by the Institute for Nuclear Research and Nuclear Energy of the Bulgarian Academy of Sciences and the Flerov Laboratory of Nuclear Reaction if the Joint Institute for Nuclear Research (Dubna). The co-organizer of the School was the Bulgarian Nuclear Regulatory Agency. According to a long-standing tradition the School has been held biannually since 1973. The School's program has been restructured according to our enlarged new international links and today it is more similar to an international conference than to a classical nuclear physics school. In 2015, the International Symposium on Exotic Nuclei (ISEN-2015) was scheduled from 8-11 September under the auspices of the School. The Symposium was dedicated to the investigation of nuclei in extreme states and, in particular, at the limits of nuclear stability (from very light neutron- and proton-rich up to superheavy nuclei). This new format attracted many young scientists and students from around the world. We had the pleasure of welcoming more than 60 distinguished scientists as lecturers. Additionally, 20 young colleagues received the opportunity to present a short contribution. In all, 90 participants enjoyed the scientific presentations and discussions as well as the relaxing atmosphere at the beach and during the pleasant evenings. The program of the School and the Symposium ranged from the latest results in fundamental areas such as nuclear structure and reactions to frontier issues of the application of nuclear methods. The main topics were the following: Exotic Nuclei and their Properties

The Third International Symposium on Space Terahertz Technology: Symposium proceedings

Science.gov (United States)

1992-01-01

Papers from the symposium are presented that are relevant to the generation, detection, and use of the terahertz spectral region for space astronomy and remote sensing of the Earth's upper atmosphere. The program included thirteen sessions covering a wide variety of topics including solid-state oscillators, power-combining techniques, mixers, harmonic multipliers, antennas and antenna arrays, submillimeter receivers, and measurement techniques.

Quality assurance and demolition: 2006 symposium

International Nuclear Information System (INIS)

Thierfeldt, S.

2006-01-01

The '2006 Symposium: Quality Assurance and Demolition' jointly organized by compra GmbH and Brenk Systemplanung GmbH this year again focused on quality assurance and the demolition of nuclear facilities as its main topics. The papers presented ranged from issues of clearance and disposal to demolition technologies and status reports about specific demolition projects. The sixteen presentations at the '2006 Symposium: Quality Assurance and Demolition' offered an interesting and very topical cross section of decommissioning and demolition of nuclear facilities in Germany. In 2007, the conference about similar main topics will again be held at the Schloss Bensberg Grand Hotel. (orig.)

"To Study the Relationship of Academic Stress and Socio-Economic Status among IX Standard Students of Raipur City"

Science.gov (United States)

Khan, Suhail Ahmed; Ayyub, Khan Farhat

2013-01-01

This paper focuses on the relationship between academic stress and socio-economic status among IX standard students. The research was carried out in Raipur City (Chhattisgarh) on a sample of 600 IX standard students of English and Hindi medium schools. Academic Stress was measured by Stress Inventory for School Students prepared by Seema Rani…

Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer.

Science.gov (United States)

Buchlis, George; Podsakoff, Gregory M; Radu, Antonetta; Hawk, Sarah M; Flake, Alan W; Mingozzi, Federico; High, Katherine A

2012-03-29

In previous work we transferred a human factor IX-encoding adeno-associated viral vector (AAV) into skeletal muscle of men with severe hemophilia B. Biopsy of injected muscle up to 1 year after vector injection showed evidence of gene transfer by Southern blot and of protein expression by IHC and immunofluorescent staining. Although the procedure appeared safe, circulating F.IX levels remained subtherapeutic (< 1%). Recently, we obtained muscle tissue from a subject injected 10 years earlier who died of causes unrelated to gene transfer. Using Western blot, IHC, and immunofluorescent staining, we show persistent factor IX expression in injected muscle tissue. F.IX transcripts were detected in injected skeletal muscle using RT-PCR, and isolated whole genomic DNA tested positive for the presence of the transferred AAV vector sequence. This is the longest reported transgene expression to date from a parenterally administered AAV vector, with broad implications for the future of muscle-directed gene transfer.

Intracellular localization analysis of npAu-PpIX in HeLa cells using specific dyes and confocal microscopy

Science.gov (United States)

Roblero-Bartolón, Victoria Gabriela; Maldonado-Alvarado, Elizabeth; Galván-Mendoza, José Iván; Ramón-Gallegos, Eva

2012-10-01

Cervical carcinoma (CC) represents the second leading cause of cancer death in Mexican women. No conventional treatments are being developed such as photodynamic therapy (PDT), involving the simultaneous presence of a photosensitizer (Ps), light of a specific wavelength and tissue oxygen. On the other hand, it has seen that the use of gold nanoparticles coupled to protoporphyrin IX increases the effectiveness of PDT. The aim of this study was to determine the site of accumulation of the conjugate npAu-PpIX in cells of cervical cancer by the use of specific dyes and confocal microscopy. The results indicate that the gold nanoparticles coupled to protoporphyrin IX are accumulated in both the cytoplasm and nucleus of HeLa cells.

Analyses of the Sn IX-Sn XII spectra in the EUV region

International Nuclear Information System (INIS)

Churilov, S S; Ryabtsev, A N

2006-01-01

The Sn IX-Sn XII spectra excited in a vacuum spark have been analysed in the 130-160 A wavelength region. The analysis was based on the energy parameter extrapolation in the isonuclear Sn VI-VIII and Sn XIII-XIV sequence. 266 spectral lines belonging to the 4d m -(4d m-1 4f+4p 5 4d m+1 ) (m=6-3) transition arrays were classified in the Sn IX-Sn XII spectra for the first time. All 18 level energies of the 4d 3 configuration and 39 level energies of the strongly interacting 4d 2 4f and 4p 5 4d 4 configurations were established in the Sn XII spectrum. The energy differences between the majority of the 4d m levels and about 40 levels of the 4d m-1 4f+4p 5 4d m+1 configurations were determined in each of the Sn IX, Sn X and Sn XI spectra (m=6-4). As a result, all intense lines were classified in the 130-140 A region relevant to the extreme ultraviolet (EUV) lithography. It was shown that the most of the intense lines in the 2% bandwidth at 135 A belong to the transitions in the Sn XI-Sn XIII spectra

Comparative gut physiology symposium: The microbe-gut-brain axis

Science.gov (United States)

The Comparative Gut Physiology Symposium titled “The Microbe-Gut-Brain Axis” was held at the Joint Annual Meeting of the American Society of Animal Science and the American Dairy Science Association on Thursday, July 21, 2016, in Salt Lake City Utah. The goal of the symposium was to present basic r...

Proceedings of the 2010 symposium on nuclear data

International Nuclear Information System (INIS)

Watanabe, Yukinobu; Koura, Hiroyuki; Chiba, Satoshi

2011-09-01

The 2010 symposium on nuclear data organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) was held at C-CUBE, Chikushi Campus, Kyushu University, on November 25 and 26, 2010, with approximately 60 domestic and foreign participants, in cooperation with Advanced Science Research Center of JAEA and under financial support from the Kyushu Branch of AESJ. The symposium was devoted to presentations and discussions about recent research results in a wide variety of fields associated with nuclear data, such as JENDL-4 related evaluation and benchmark tests, nuclear data measurements and facilities, theoretical model calculations, applications, and so on. A tutorial on nuclear data evaluation for actinide nuclides was given in the symposium. This report consists of total 40 papers including 15 oral presentations and 25 poster presentations. (author)

ACS Symposium on Molecular Tribology

National Research Council Canada - National Science Library

Gellman, Andrew

2002-01-01

.... The aspects of tribology covered by the symposium were quite broad but included a number of areas of importance to Air Force technologies including vapor phase lubrication, lubrication of MEMS...

Killing malignant melanoma cells with protoporphyrin IX-loaded polymersome-mediated photodynamic therapy and cold atmospheric plasma

Directory of Open Access Journals (Sweden)

Wang M

2017-05-01

Full Text Available Mian Wang,1 Benjamin M Geilich,2 Michael Keidar,3 Thomas J Webster1,4 1Department of Chemical Engineering, 2Department of Bioengineering, Northeastern University, Boston, MA, 3Department of Mechanical and Aerospace Engineering, George Washington University, Washington, DC, USA; 4Wenzhou Institute of Biomaterials and Engineering, Wenzhou Medical University, Wenzhou, People’s Republic of China Abstract: Traditional cancer treatments contain several limitations such as incomplete ablation and multidrug resistance. It is known that photodynamic therapy (PDT is an effective treatment for several tumor types especially melanoma cells. During the PDT process, protoporphyrin IX (PpIX, an effective photosensitizer, can selectively kill cancer cells by activating a special light source. When tumor cells encapsulate a photosensitizer, they can be easily excited into an excited state by a light source. In this study, cold atmospheric plasma (CAP was used as a novel light source. Results of some studies have showed that cancer cells can be effectively killed by using either a light source or an individual treatment due to the generation of reactive oxygen species and electrons from a wide range of wavelengths, which suggest that CAP can act as a potential light source for anticancer applications compared with UV light sources. Results of the present in vitro study indicated for the first time that PpIX can be successfully loaded into polymersomes. Most importantly, cell viability studies revealed that PpIX-loaded polymersomes had a low toxicity to healthy fibroblasts (20% were killed at a concentration of 400 µg/mL, but they showed a great potential to selectively kill melanoma cells (almost 50% were killed. With the application of CAP posttreatment, melanoma cell viability significantly decreased (80% were killed compared to not using a light source (45% were killed or using a UV light source (65% were killed. In summary, these results indicated for the

Lacerations to Zones VIII and IX: It Is Not Just a Tendon Injury

Directory of Open Access Journals (Sweden)

Charla R. Fischer

2011-01-01

Full Text Available Extensor tendon injuries are widely believed to be straightforward problems that are relatively simple to manage. However, these injuries can be complex and demand a thorough understanding of anatomy to achieve the best functional outcomes. When lacerations occur in the forearm as in Zones VIII and IX injury, the repair of the extensor tendon and muscle, and posterior interosseous nerve (PIN is often challenging. A review of the literature shows little guidance and attention for these injuries. We present four patients with injuries to Zones VIII and IX as well as a review of surgical technique, postoperative rehabilitation, and pearls that may be of benefit to those managing these injuries.

Two-peaked 5-ALA-induced PpIX fluorescence emission spectrum distinguishes glioblastomas from low grade gliomas and infiltrative component of glioblastomas.

Science.gov (United States)

Montcel, Bruno; Mahieu-Williame, Laurent; Armoiry, Xavier; Meyronet, David; Guyotat, Jacques

2013-04-01

5-ALA-induced protoporphyrin IX (PpIX) fluorescence enables to guiding in intra-operative surgical glioma resection. However at present, it has yet to be shown that this method is able to identify infiltrative component of glioma. In extracted tumor tissues we measured a two-peaked emission in low grade gliomas and in the infiltrative component of glioblastomas due to multiple photochemical states of PpIX. The second emission peak appearing at 620 nm (shifted by 14 nm from the main peak at 634 nm) limits the sensibility of current methods to measured PpIX concentration. We propose new measured parameters, by taking into consideration the two-peaked emission, to overcome these limitations in sensitivity. These parameters clearly distinguish the solid component of glioblastomas from low grade gliomas and infiltrative component of glioblastomas.

Organizational Change. Symposium 11. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

Science.gov (United States)

2000

This packet contains three papers from a symposium on organizational change. The first paper, "Kaizen Blitz: Rapid Learning to Facilitate Immediate Organizational Improvements" (Robert B. Gudgel, Fred C. Feitler), describes rapid and dramatic improvement in the organizational performance of a manufacturing firm after use of a series of…

Symposium 3 of JENAM 2010

CERN Document Server

Recchi, Simone; Hensler, Gerhard; Dwarf Galaxies Keys to Galaxy Formation and Evolution

2012-01-01

Dwarf galaxy research constitutes an extremely vibrant field of astrophysical research, with many long-standing questions still unsettled and new ones constantly arising. The intriguing diversity of the dwarf galaxy population, observed with advanced ground-based and space-borne observatories over a wide spectral window providing an unprecedented level of detail, poses new challenges for both observers and theoreticians. The aim of this symposium was to bring together these two groups to exchange ideas and new results on the many evolutionary aspects of and open issues concerning dwarf galaxies. The main topics addressed include: • the birth of dwarf galaxies: theoretical concepts and observable relics across wavelength and time • the morphological, structural and chemical evolution of dwarf galaxies • possible evolutionary connections between early-type and late-type dwarfs • the star formation history of dwarf galaxies and its dependence on intrinsic and environmental properties • the origin ...

Proceedings of the 1st JAERI symposium on HTGR technologies

International Nuclear Information System (INIS)

1990-07-01

This report was edited as the Proceedings of the 1st JAERI Symposium on HTGR Technologies, - Design, Licensing Requirements and Supporting Technologies -, collecting the 21 papers presented in the Symposium. The 19 of the presented papers are indexed individually. (J.P.N.)

SYMPOSIUM ON REMOTE SENSING IN THE POLAR REGIONS

Science.gov (United States)

The Arctic Institute of North America long has been interested in encouraging full and specific attention to applications of remote sensing to polar...research problems. The major purpose of the symposium was to acquaint scientists and technicians concerned with remote sensing with some of the...special problems of the polar areas and, in turn, to acquaint polar scientists with the potential of the use of remote sensing . The Symposium therefore was

Proceedings of the symposium on technology in laboratories

International Nuclear Information System (INIS)

1988-10-01

The Symposium on Technology in Laboratories was held on March 29 and 30, 1988 at Toyota Auditorium in Nagoya University. This symposium was hosted by Institute of Plasma Physics. Participants were about 210 and 54 papers were presented from many of Japanese universities and laboratories. Technical experience and new technics were reported and discussed divided into five sessions; technologies of manufacture, cryogenic, diagonostic and control system, computer and experimental apparatus. (author)

Report on the First International Symposium Science in Judo (ISSJ

Directory of Open Access Journals (Sweden)

Félix Mateo-Cubo

2017-12-01

Full Text Available This report resumes the First International Symposium Science in Judo (ISSJ, organized by the Department of Health Psychology, Miguel Hernández University, Elche (Spain, and held from October 12 to 14h, 2017. During this symposium some of the most relevant research projects related to judo as a sport were presented. There were a wide variety of topics, including biomechanics of technique, health, psychology, nutrition, sport training, education and future prospects. Five plenary sessions, six mini-sessions, one panel discussion and two workshops on tatami were developed. The symposium was an event where important national and international researchers participated. It was intended for groups related to judo, such as Sports Sciences students, judo coaches and high level judo athletes. More than 70 people participated in the symposium whose main aim was to provide scientific evidence on judo to judo professionals.

Proceedings of the symposium on measurements of neutron energy spectra using recoil proton proportional counters

International Nuclear Information System (INIS)

Urabe, Itsumasa

1986-01-01

This is a report of the symposium on measurements of neutron energy spectra using recoil proton proportional counters held at the Research Reactor Institute of Kyoto University on January 27 in 1986. An energy resolution, wall effects of response functions, n · γ discrimination methods and other fundamental properties of recoil proton counters are discussed for a new development of an application of this counter. (author)

Third Symposium on Macrocyclic Compounds

International Nuclear Information System (INIS)

1979-01-01

At the Third Symposium on Macrocyclic Compounds there were sessions on facilitated transport, analytical applications, organic synthesis and reactions, phase transfer catalysis, and metal complexation. Abstracts of the individual presentations are included

First Ladies' Symposium on Early Childhood in Egypt (Cairo, Egypt, May 21, 2001).

Science.gov (United States)

O'Gara, Chloe

This document is comprised of the papers presented at the First Ladies' Symposium on Early Childhood in Egypt in May 2001. Participating in the symposium were representatives from the World Bank, the Amsterdam Institute for International Development, the Children's Project, and the Academy for Educational Development. The symposium opened with an…

Two novel mutations in the PPIB gene cause a rare pedigree of osteogenesis imperfecta type IX.

Science.gov (United States)

Jiang, Yu; Pan, Jingxin; Guo, Dongwei; Zhang, Wei; Xie, Jie; Fang, Zishui; Guo, Chunmiao; Fang, Qun; Jiang, Weiying; Guo, Yibin

2017-06-01

Osteogenesis imperfecta (OI) is a rare genetic skeletal disorder characterized by increased bone fragility and vulnerability to fractures. PPIB is identified as a candidate gene for OI-IX, here we detect two pathogenic mutations in PPIB and analyze the genotype-phenotype correlation in a Chinese family with OI. Next-generation sequencing (NGS) was used to screen the whole exome of the parents of proband. Screening of variation frequency, evolutionary conservation comparisons, pathogenicity evaluation, and protein structure prediction were conducted to assess the pathogenicity of the novel mutations. Sanger sequencing was used to confirm the candidate variants. RTQ-PCR was used to analyze the PPIB gene expression. All mutant genes screened out by NGS were excluded except PPIB. Two novel heterozygous PPIB mutations (father, c.25A>G; mother, c.509G>A) were identified in relation to osteogenesis imperfecta type IX. Both mutations were predicted to be pathogenic by bioinformatics analysis and RTQ-PCR analysis revealed downregulated PPIB expression in the two carriers. We report a rare pedigree with an autosomal recessive osteogenesis imperfecta type IX (OI-IX) caused by two novel PPIB mutations identified for the first time in China. The current study expands our knowledge of PPIB mutations and their associated phenotypes, and provides new information on the genetic defects associated with this disease for clinical diagnosis. Copyright © 2017 Elsevier B.V. All rights reserved.

Sanibel Symposium in the Petascale-Exascale Computational Era

Energy Technology Data Exchange (ETDEWEB)

Cheng, Hai-Ping [Univ. of Florida, Gainesville, FL (United States)

2016-12-23

The 56^th Sanibel Symposium was held February 14-19 2016 at the King and Prince Hotel, St. Simons Island, GA. It successfully brought quantum chemists and chemical and condensed matter physicists together in presentations, posters, and informal discussions bridging those two communities. The Symposium has had a significant role in preparing generations of quantum theorists. As computational potency and algorithmic sophistication have grown, the Symposium has evolved to emphasize more heavily computationally oriented method development in chemistry and materials physics, including nanoscience, complex molecular phenomena, and even bio-molecular methods and problems. Given this context, the 56^th Sanibel meeting systematically and deliberately had sessions focused on exascale computation. A selection of outstanding theoretical problems that need serious attention was included. Five invited sessions, two contributed sessions (hot topics), and a poster session were organized with the exascale theme. This was a historic milestone in the evolution of the Symposia. Just as years ago linear algebra, perturbation theory, density matrices, and band-structure methods dominated early Sanibel Symposia, the exascale sessions of the 56^thmeeting contributed a transformative influence to add structure and strength to the computational physical science community in an unprecedented way. A copy of the full program of the 56^th Symposium is attached. The exascale sessions were Linear Scaling, Non-Adabatic Dynamics, Interpretive Theory and Models, Computation, Software, and Algorithms, and Quantum Monte Carlo. The Symposium Proceedings will be published in Molecular Physics (2017). Note that the Sanibel proceedings from 2015 and 2014 were published as Molecular Physics vol. 114, issue 3-4 (2016) and vol. 113, issue 3-4 (2015) respectively.

Transport arrangements for the scientific symposium

CERN Multimedia

2000-01-01

Parking in the region of building 180 will be severely restricted during the LEPFest scientific symposium of 10-11 October, and a special bus service will operate to ferry people to and from the event. From 8:00 am, buses will leave the reception at building 33, stop to pickup passengers outside the hostels (buildings 38 and 39), and drop people off at the symposium venue - building 180. At the end of each day’s proceedings, the buses will bring people back, and through out the day a shuttle service will operate around every 15-20 minutes. Attendees are strongly recommended to use the buses.

11th AG STAB/DGLR Symposium

CERN Document Server

Heinemann, Hans-Joachim; Hilbig, Reinhard

1999-01-01

This volume contains the papers of the 11th Symposium of the AG STAB (German Aerospace Aerodynamics Association). In this association those scientists and engineers from universities, research-establishments and industry are involved, who are doing research and project work in numerical and experimental fluid mechanics and aerodynamics for aerospace and other applications. Many of the contributions are giving results from the "Luftfahrtforschungsprogramm der Bundesregierung (German Aeronautical Research Programme). Some of the papers report on work sponsored by the Deutsche Forschungsgemeinschaft, DFG, which also was presented at the symposium. The volume gives a broad overview over the ongoing work in this field in Germany.

The 13th Tihany Symposium on Radiation Chemistry

Science.gov (United States)

Wojnárovits, László; Takács, Erzsébet

2016-07-01

The Symposium was held in Balatonalmádi, a beautiful city by the Lake Balaton, Hungary, between August 29 and September 3, 2015. This time - to meet the expectations of many colleagues and friends - a place close to the village Tihany was selected, where the first Tihany Symposium was organized in 1962. The participants beside the excellent lectures could also enjoy the panorama of the Lake from the rooms and from the terrace of Hotel Ramada. The number of participants was close to 170 from about 33 countries. The highest number of participants arrived from Poland (14), followed by France (11), Turkey (9) and China (9). The Symposium had 6-6 colleagues from Brazil, Israel, and Romania. Beside China, Asia was represented by a few scientists from the Republic of Korea, Malaysia, Thailand, Philippines and from Saudi Arabia.

Proceedings of the 1992 symposium on nuclear data

Energy Technology Data Exchange (ETDEWEB)

Baba, Mamoru [ed.; Tohoku Univ., Sendai (Japan); Nakagawa, Tsuneo [ed.; Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1993-03-15

The 1992 Symposium on Nuclear Data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 26th and 27th of November, 1992. The symposium was organized by Japanese Nuclear Data Committee and Nuclear Data Center, JAERI. The program of the symposium is listed below. In the oral session, a total of 15 papers were presented under the sessions of present status of revision work of JENDL-3, adjustment of group constants, nuclear data in medium energy region, nuclear data evaluation methods, integral data analyses and topics. In the poster session, presented were 25 papers concerning experiments, evaluations and benchmark tests of nuclear data. Activities of JNDC working groups were also displayed in the poster session. All of the 40 papers except the reports from JNDC working groups are compiled in this proceedings.

Birch symposium proceedings

Science.gov (United States)

W.T. Doolittle; P.E. Bruns

1969-01-01

This symposium on yellow and paper birch is the third in a series of meetings devoted to discussion of our fine hardwood timber species. The first meeting, held at Carbondale, Illinois, in 1966, dealt with black walnut. The second, held at Houghton, Michigan, in 1968, dealt with sugar maple. The purpose of this third meeting is to bring together our present knowledge...

Proceedings of the international symposium NUCEF 2005

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-08-01

Japan Atomic Energy Research Institute (JAERI) held the international symposium NUCEF 2005 at Techno Community Square RICOTTI in Tokai-mura on February 9 and 10, 2005. This symposium was co-organized by Japan Nuclear Cycle Development Institute (JNC), and Nuclear Fuel Cycle Safety Research Committee authorized the program. Two hundred thirty-nine participants from 11 countries presented fifty-nine papers, and discussed recent research activities and its outputs on waste disposal safety, fuel cycle facility safety including criticality safety, and separation process development. The presented papers are compiled in the proceedings. (author)

Outcome of UNIDO symposium on biomass energy

International Nuclear Information System (INIS)

Nazemi, A.H.

1997-01-01

The results of the UNIDO symposium are presented. The symposium covered a variety of subjects, beginning with a comparison of biomass energy production and potential uses in different regions, specific country case studies about the present situation and trends in biomass energy utilisation. Technological aspects discussed included the production of biomass resources, their conversion into energy carriers and technology transfer to developing countries. An analysis of financial resources available and mechanisms for funding biomass projects were given. Environmental effects and some relatively successful biomass projects under development were described. (K.A.)

Symposium on high temperature and materials chemistry

International Nuclear Information System (INIS)

1989-10-01

This volume contains the written proceedings of the Symposium on High Temperature and Materials Chemistry held in Berkeley, California on October 24--25, 1989. The Symposium was sponsored by the Materials and Chemical Sciences Division of Lawrence Berkeley Laboratory and by the College of Chemistry of the University of California at Berkeley to discuss directions, trends, and accomplishments in the field of high temperature and materials chemistry. Its purpose was to provide a snapshot of high temperature and materials chemistry and, in so doing, to define status and directions

Symposium on high temperature and materials chemistry

Energy Technology Data Exchange (ETDEWEB)

1989-10-01

This volume contains the written proceedings of the Symposium on High Temperature and Materials Chemistry held in Berkeley, California on October 24--25, 1989. The Symposium was sponsored by the Materials and Chemical Sciences Division of Lawrence Berkeley Laboratory and by the College of Chemistry of the University of California at Berkeley to discuss directions, trends, and accomplishments in the field of high temperature and materials chemistry. Its purpose was to provide a snapshot of high temperature and materials chemistry and, in so doing, to define status and directions.

Proceedings of the First International Symposium on Robust Design 2014

DEFF Research Database (Denmark)

The symposium concerns the topic of robust design from a practical and industry orientated perspective. During the 2 day symposium we will share our understanding of the need of industry with respect to the control of variance, reliability issues and approaches to robust design. The target audience...

International Evoked Potentials Symposium

CERN Document Server

1980-01-01

The past decade has seen great progress in the measurement of evoked potentials in man; a steady increase in our understanding of their charac­ teristics, their origins and their usefulness; and a growing application in the field of clinical diagnosis. The topic is a truly multidisciplinary one. Important research contributions have been made by workers of many different backgrounds and clinical applications span the specialities. This book represents a revised and updated version of the work originally presented at the international evoked potential symposium held in Nottingham 4-6 1978. The Nottingham Symposium provided a forum for a state-of-the-art discussion amongst workers from many different disciplines and from many different countries. For each major topic in the field an expert review set the scene for discussion of current research presentations. This format is retained in the book: the chapters in Part A provide the context in which the research presented in Part B is set. The task of selecting m...

Massive WDM and TDM Soliton Transmission Systems : a ROSC Symposium

CERN Document Server

2002-01-01

This book summarizes the proceedings of the invited talks presented at the “International Symposium on Massive TDM and WDM Optical Soliton Tra- mission Systems” held in Kyoto during November 9–12, 1999. The symposium is the third of the series organized by Research Group for Optical Soliton C- munications (ROSC) chaired by Akira Hasegawa. The research group, ROSC, was established in Japan in April 1995 with a support of the Japanese Ministry of Post and Telecommunications to promote collaboration and information - change among communication service companies, communication industries and academic circles in the theory and application of optical solitons. The symposium attracted enthusiastic response from worldwide researchers in the field of soliton based communications and intensive discussions were made. In the symposium held in 1997, new concept of soliton transmission based on dispersion management of optical fibers were presented. This new soliton is now called the dispersion managed soliton. The p...

Ninth international symposium on radiopharmacology

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-31

The goal of this Symposium is to provide a forum for those international scientists involved in applying the principles of pharmacology and radiation biology to the development of agents for the diagnosis and treatment of disease. The program will highlight state-of-the-art progress in the development of those agents used in conjunction with some form of radiation such as radiopharmaceuticals, radiopaques, photo- and radiosensitizing drugs, and neutron capture agents. An underlying pharmacokinetic parameter associated with all these agents is the need for site-specific delivery to an organ or tumor. Therefore, a major goal of the symposium will be to address those pharmacologic principles for targeting molecules to specific tissue sites. Accordingly, session themes will include receptor-mediated processes, membrane transporters, antibody interactions, metabolic trapping, and oligonucleotide-antisense mechanisms.

Ninth international symposium on radiopharmacology

International Nuclear Information System (INIS)

1995-01-01

The goal of this Symposium is to provide a forum for those international scientists involved in applying the principles of pharmacology and radiation biology to the development of agents for the diagnosis and treatment of disease. The program will highlight state-of-the-art progress in the development of those agents used in conjunction with some form of radiation such as radiopharmaceuticals, radiopaques, photo- and radiosensitizing drugs, and neutron capture agents. An underlying pharmacokinetic parameter associated with all these agents is the need for site-specific delivery to an organ or tumor. Therefore, a major goal of the symposium will be to address those pharmacologic principles for targeting molecules to specific tissue sites. Accordingly, session themes will include receptor-mediated processes, membrane transporters, antibody interactions, metabolic trapping, and oligonucleotide-antisense mechanisms

1979 international symposium on lepton and photon interactions at high energies

Energy Technology Data Exchange (ETDEWEB)

Kirk, T.B.W.; Abarbanel, H.D.I.

1979-01-01

This symposium on Leptons and Photons is ninth in the series of biannual meetings which began at Cambridge, Massachusetts, in 1963. Abstracts of individual items from the symposium were prepared separately for the data base. (GHT)

International symposium on NMR spectroscopy

International Nuclear Information System (INIS)

The publication consists of 32 papers and presentations from the field of NMR spectroscopy applications submitted to the International Symposium on NMR Spectroscopy held at Smolenice between 29 Sep and 3 Oct, 1980. (B.S.)

Proceedings of the 5th underground coal conversion symposium

Energy Technology Data Exchange (ETDEWEB)

None

1979-05-01

The 5th underground coal conversion symposium was held at Alexandria, Virginia, June 18--21, 1979. Thirty-three papers have been entered individually into EDB and ERA. Seven papers were also abstracted for Energy Abstracts for Policy Analysis. Seven papers had been entered previously from other sources. The symposium was sponsored by the US Department of Energy, Division of Fossil Fuel Extraction. (LTN)

Physiology and Endocrinology Symposium. Factors controlling puberty in beef heifers

Science.gov (United States)

The Physiology and Endocrinology Symposium on “Factors controlling puberty in beef heifers” was held at the joint annual meeting of the American Dairy Science Association and the American Society of Animal Science in New Orleans, Louisiana, USA, July 10 to 14, 2011. The objective of the symposium w...

Proceedings of the 13th symposium on advanced photon research

International Nuclear Information System (INIS)

2013-09-01

The 13th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa-shi, Kyoto on November 15 - 16, 2012. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. (author)

Symposium summary and prognosis

International Nuclear Information System (INIS)

Bjorken, J.D.

1975-11-01

The summary of the symposium on high energy physics experiments includes phenomena at low energies, the foundations of physics (considered to be mainly gravitation and quantum electrodynamics), standards of reference used for interpretation of experimental data, the new physics, particle proliferation, theoretical development, and a prognosis for the future

Seleção de genótipos de cana-de-açúcar para acúmulo de protoporfirina ix com uso de herbicidas inibidores da protox Selection of Sugarcane Genotypes for Protoporphyrin IX Accumulation using Protox-Inhibiting Herbicides

Directory of Open Access Journals (Sweden)

L.R.M. Barberis

2009-01-01

Full Text Available O objetivo do presente trabalho foi selecionar genótipos de cana-de-açúcar por meio de inibidores da PROTOX e antioxidantes para indução do acúmulo de protoporfirina IX (PROTO IX e/ou de seus precursores em plantas. Esses compostos podem ser utilizados como agentes sensibilizantes em terapia fotodinâmica (TFD, os quais possibilitam uma fonte de baixo custo para o tratamento de neoplasias e carcinomas. O experimento foi montado em câmara climatizada, com aplicação de nove tratamentos (1. oxyfluorfen + glutamato monossódico + vitaminas C e E; 2. oxyfluorfen + glutamato monossódico + vitaminas C e E + ácido levulênico; 3. oxyfluorfen; 4. carfentrazone + glutamato monossódico + vitaminas C e E; 5. carfentrazone + glutamato monossódico + vitaminas C e E + ácido levulênico; 6. carfentrazone; 7. testemunha + vitaminas C e E; 8. testemunha + vitaminas C e E + ácido levulênico; e 9. testemunha em oito genótipos de cana-de-açúcar (PO933499, RB806043, RB470355, PO830698, SP701143, PO901387, PO894414 e SP903414, dispostos em esquema fatorial 9 x 8, com quatro repetições. As repetições constituíram-se de folhas (20 cm destacadas de cada genótipo, sendo estas pulverizadas com os tratamentos mencionados, em simulador estacionário. Foram realizadas avaliações visuais de controle aos 2 DAA (dias após aplicação e, no fim do estudo, determinações analíticas via extração da biomassa fresca, verificando os teores de protoporfirina IX por cromatografia líquida de alta eficiência. Os resultados mostraram que em curto prazo foram detectados aumentos significativos nas concentrações de PROTO IX para os genótipos RB470355 e SP903414 submetidos ao tratamento 2 e para o genótipo SP701143 submetido ao tratamento 8, indicando que eles podem ser utilizados como fontes acumuladoras de protoporfirina IX.The objective of this study was to select sugarcane genotypes through PROTOX inhibitors and antioxidants to induce the accumulation

Comparative study of protoporphyrin IX fluorescence image enhancement methods to improve an optical imaging system for oral cancer detection

Science.gov (United States)

Jiang, Ching-Fen; Wang, Chih-Yu; Chiang, Chun-Ping

2011-07-01

Optoelectronics techniques to induce protoporphyrin IX fluorescence with topically applied 5-aminolevulinic acid on the oral mucosa have been developed to noninvasively detect oral cancer. Fluorescence imaging enables wide-area screening for oral premalignancy, but the lack of an adequate fluorescence enhancement method restricts the clinical imaging application of these techniques. This study aimed to develop a reliable fluorescence enhancement method to improve PpIX fluorescence imaging systems for oral cancer detection. Three contrast features, red-green-blue reflectance difference, R/B ratio, and R/G ratio, were developed first based on the optical properties of the fluorescence images. A comparative study was then carried out with one negative control and four biopsy confirmed clinical cases to validate the optimal image processing method for the detection of the distribution of malignancy. The results showed the superiority of the R/G ratio in terms of yielding a better contrast between normal and neoplastic tissue, and this method was less prone to errors in detection. Quantitative comparison with the clinical diagnoses in the four neoplastic cases showed that the regions of premalignancy obtained using the proposed method accorded with the expert's determination, suggesting the potential clinical application of this method for the detection of oral cancer.

Tenth annual underground coal gasification symposium: proceedings

Energy Technology Data Exchange (ETDEWEB)

Burwell, E.; Docktor, L.; Martin, J.W. (eds.)

1984-12-01

The Tenth Annual Underground Coal Gasification Symposium was cosponsored by the Fossil Energy Division of the US Department of Energy and the Morgantown Energy Technology Center's Laramie Projects Office. The purpose of the symposium was to provide a forum for presenting research results and for determining additional research needs in underground coal gasification. This years' meeting was held in Williamsburg, Virginia, during the week of August 12 through 15, 1984. Approximately 120 attendees representing industry, academia, national laboratories, Government, and eight foreign countries participated in the exchange of ideas, results, and future research plans. International representatives included participants from Belgium, Brazil, France, the Netherlands, New Zealand, Spain, West Germany, and Yugoslavia. During the three-day symposium, sixty papers were presented and discussed in four formal presentation sessions and two informal poster sessions. The papers describe interpretation of field test data, results of environmental research, and evaluations of laboratory, modeling, and economic studies. All papers in this Proceedings have been processed for inclusion in the Energy Data Base.

Collaborative Care Transitions Symposium: Insights from Participants.

Science.gov (United States)

Jeffs, Lianne; Saragosa, Marianne; Zahradnik, Michelle; Maione, Maria; Hindle, Aimee; Santiago, Cecilia; Krock, Murray; Stergiopoulos, Vicky; Bulmer, Beverly; Mitchell, Kaleil; McNamee, Colleen; Ramji, Noor

2017-01-01

There are promising signs that interprofessional collaborative practice is associated with quality care transitions and improved access to patient-centred healthcare. A one-day symposium was held to increase awareness and capacity to deliver quality collaborative care transitions to interprofessional health disciplines and service users. A mixed methods study was used that included a pre-post survey design and interviews to examine the impact of the symposium on knowledge, attitudes and practice change towards care transitions and collaborative practice with symposium participants. Our survey results revealed a statistically significant increase in only a few of the scores towards care transitions and collaborative practice among post-survey respondents. Three key themes emerged from the qualitative analysis, including: (1) engaging the patient at the heart of interprofessional collaboration and co-design of care transitions; (2) having time to reach out, share and learn from each other; and (3) reflecting, reinforcing and revising practice. Further efforts that engage inter-organizational learning by exchanging knowledge and evaluating these forums are warranted. Copyright © 2017 Longwoods Publishing.

Contemporary Physics: Trieste Symposium 1968. Vol. I. Proceedings of the International Symposium on Contemporary Physics

International Nuclear Information System (INIS)

1969-01-01

In June 1968, the International Centre for Theoretical Physics was privileged to hold an extended symposium on contemporary physics — an event probably unique in that its aim was to range over and review not just one specialized aspect of modern physics but its entire spectrum. The symposium brought together a group of 300 leading specialists in particle physics, theory of condensed matter, astrophysics, relativity, plasma physics, cosmology, nuclear physics, quantum electronics and biophysics; they lived together for three weeks, to deliver, to discuss and to listen to lectures in depth on their various specialities. The intention was to acquire, if possible, a deeper sense of the scope and unified nature of the general subject — physics — by sharing the insights of its fascinatingly diverse disciplines. The present two volumes are a record of the proceedings of the symposium. The first groups papers presented on condensed and plasma matter, on earth and in the universe; the second deals with theory of matter at very small distances and fundamentals of quantum theory. How far did we succeed in achieving the objectives of the symposium? Did we succeed in communicating to those in other disciplines the present situation in our own — the problems, the prospects? Did we emerge, three weeks after, as universal in our outlook and competence as the great physicists of even forty years ago, who could, with felicity, pass from one discipline to another enriching each? How much cross-fertilization was achieved? To what extent were the hierarchy of disciplines and the barriers between generations broken? In retrospect — and particularly in retrospect — the answers to these questions appear positive: we succeeded perhaps partially; but far more than anyone anticipated. There is no doubt that communication is a difficult art. There was so much ground to be covered before the treasures of one's own discipline could be unfolded. We could not easily forget those in

Proceedings of DAE-BRNS third international symposium on materials chemistry

International Nuclear Information System (INIS)

Tyagi, Deepak; Banerjee, Atindra Mohan; Nigam, Sandeep; Varma, Salil; Tripathi, Arvind Kumar; Bharadwaj, Shyamala Rajkumar; Das, Dasarathi

2010-12-01

The present volume consists of the proceedings of the DAE-BRNS Third International Symposium on Materials Chemistry. In order to keep pace with the advancements made in the area of materials chemistry, new topics like materials for energy conversion, biomaterials, carbon based materials, soft condensed materials, thin films, surface chemistry, polymer based materials, organic and organometallics, magnetic materials and high purity materials have been included in this symposium while topics like nuclear materials, nanomaterials and clusters, catalysis, chemical sensors, fuel cell materials and computational research in materials chemistry have been continued as important features of the symposium. Papers relevant to INIS are indexed separately

Li-Fraumeni syndrome: Discovery and future challenges - Joseph Fraumeni Symposium

Science.gov (United States)

In May 2014, NCI’s Division of Cancer Epidemiology and Genetics (DCEG) hosted Cancer Epidemiology: From Pedigrees to Populations, a scientific symposium honoring 50 years of visionary leadership by Dr. Joseph F. Fraumeni, Jr., the founding Director of DCEG. In this video, Dr. Stephen Chanock of NCI provides opening remarks. Dr. David Schottenfeld of the University of Michigan moderates a session on the search for cancer susceptibility genes. Dr. Louise Strong of University of Texas MD Anderson Cancer Center speaks about the discovery and future challenges of Li-Fraumeni syndrome research. For more information on this symposium, visit http://dceg.cancer.gov/news-events/Fraumeni-symposium-speakers.

2006 Rare Neuroimmunological Disorders Symposium; Sheraton Inner Harbor, Baltimore, MD, July 20-23, 2006

DEFF Research Database (Denmark)

Kerr, DA; Antel, JP; Arnold, DL

2007-01-01

On July 20-22nd 2006, the second International Rare Neuroimmunologic Disorders Symposium was held in Baltimore, Maryland. The purpose of this symposium was to bring together diverse groups interested in immune-mediated disorders of the nervous system. The symposium was not disease-specific but at...

Sex Discrimination and Intercollegiate Athletics: Putting Some Muscle on Title IX.

Science.gov (United States)

Yale Law Journal, 1979

1979-01-01

Argues that the general language of the Title IX statute, together with certain specific features of it, strongly suggests that the Department of Health, Education, and Welfare should develop more stringent and demanding regulations based on social policy considerations concerning sex discrimination in intercollegiate sports. Available from Yale…

31st International Symposium on Lattice Field Theory

CERN Document Server

2013-01-01

The annual lattice symposium brings together a global community of researchers from theoretical particle physics and beyond, who employ numerical and computational methods to study the properties of strongly interacting physical systems, above all Quantum Chromodynamics (QCD), the theory describing the interactions of quarks and gluons. Topics include studies of the spectrum and structure of hadrons, lattice studies of matter under extreme conditions, hadronic contributions to weak decay amplitudes, as well as recent developments in simulation algorithms and computer hardware. The 2013 conference in Mainz was attended by over 500 participants from all over the globe, making it the biggest in this series so far. This proceedings volume is dedicated to the memory of Nobel Laureate Kenneth G. Wilson (June 8, 1936 - June 15, 2013).

Go Tell Alcibiades: Tragedy, Comedy, and Rhetoric in Plato's "Symposium"

Science.gov (United States)

Crick, Nathan; Poulakos, John

2008-01-01

Plato's "Symposium" is a significant but neglected part of his elaborate and complex attitude toward rhetoric. Unlike the intellectual discussion of the "Gorgias" or the unscripted conversation of the "Phaedrus," the "Symposium" stages a feast celebrating and driven by the forces of "Eros." A luxuriously stylish performance rather than a rational…

3rd symposium on tires and chassis; 3. Symposium Reifen und Fahrwerk

Energy Technology Data Exchange (ETDEWEB)

Geringer, B.; Stumpf, H. (comps.)

2005-07-01

The present volume contains the talks, which were held at the 3rd symposium on ''Tires and chassis'' at the Institute for combustion machines at the Technical University Vienna on 26th September 2005 in cooperation with UAMTTC and Semperit Reifen Ges.m.H. Apart from technical improvements on chassis, tires and carriageway the overall perspective will get more important in the future, which also includes the driver, the neighbour, the environment and the traffic policy. Due to an increasing number of international participants, discussions can be expected, which will take into consideration extraordinary and manifold perspectives. The third symposium on ''Tires and chassis'' discusses the following developments, of which some are evolutionary. (a) Tire engineering; environmental aspects of tires, roll resistance of tires, driving comfort of tires, winter tires for passenger vehicles and trucks. (b) vehicle engineering, engineering of a race car chassis by means of telemetric measuring data acquisition; simulation of steering wheel vibrations on a complete vehicle test stand. (c) Vehicle steering; chassis of tracklaying vehicles; automatic air pressure control. (orig.)

FIP Symposium 1997 (South Africa); FIP Symposium 1997 (Minami Africa) ni sankashite

Energy Technology Data Exchange (ETDEWEB)

Niwano, T. [Oriental Construction Co. Ltd., Tokyo (Japan); Shinagawa, K.; Takahashi, T.

1997-07-31

FIP (Federation Internationale de la Precontrainte) Symposium was held in Johannesburg, South Africa. Ikeda and others were sent by the Japan Prestressed Concrete Engineering Association to participate the symposium and visit some bridges in Hong Kong and South Africa. As the keynote addresses, the trends of PC in South Africa, Europe, America, East Asia and Australia was reported. Japanese papers among 105 presented papers are as follows: Iwasaki`s `Construction method of the railway PC skew slab bridge, Natori-Gawa bridge`, Toda`s `Construction of the suspended slab bridge longest in the world, Yume Tsuri-bashi`, Iizuka`s `Experiment on earthquake characteristics of precast concrete columns` and Sugita`s `Study on concrete using high-activity rice hull ash`. The group visited Kap Shui Mun bridge (Hong Kong) of 750m long constructed by Japanese JV which is the 5-span continuous complex cable stayed bridge, and featured by PC box girder structure of side spans. The group also visited Gouritz River PC bridge in South Africa. 5 refs., 10 figs.

Proceedings of the symposium on the physics and technology of reactors

International Nuclear Information System (INIS)

1993-01-01

The symposium aimed at providing the opportunity for promoting the subject and for developing the human resources in this important field in the Arab States. The symposium included 32 lectures on the following topics related to research reactors: design and development, training and operation, calculations of reactor parameters, nuclear reactions dynamics and control, reactor physics, neutron pyhsics, neutron activation analysis, in-core reactor radiation protection and shielding calculations. The lectures of the symposium were distributed over 7 sessions. An additional session was held by all participants for open discussion and recommendations

Tenth international symposium on environmental biogeochemistry

Energy Technology Data Exchange (ETDEWEB)

Ehrlich, H.L.

1992-01-01

The primary task of this Symposium on Environmental Biogeochemistry was to examine our current understanding of GLOBAL CHANGE AND THE BIOGEOCHEMISTRY OF RADIATIVE TRACE GASES. The symposium was divided into 12 non-overlapping sessions: Paleoatmospheres and paleoclimates; Global distributions and atmospheric reactions; Poster presentations on the topics of sessions 1, 2, 4, 5, and 7; Terrestrial systems and land use change - 1; Terrestrial and land use change - 11; Fluxes and cycling in aquatic systems; Metals, organics, and depositional environments; Poster presentations on the topics of sessions 6, 9, 10 and 12; Biological Mechanisms of formation and destruction - 1; Biological mechanisms of formation and destruction - 11; High latitude systems; and Global sources, sinks, and feedbacks.

Aplikasi Peta Kendali p sebagai Pengendalian Kualitas Karet di PTPN IX Batujamus/Kerjoarum

Directory of Open Access Journals (Sweden)

Isti Khomah

2016-03-01

Full Text Available The increasing of global rubber consumption is an opportunity as well as a challenge for Indonesian rubber produsers to increase the quantity and the quality of production. Faced the competition between countries, the quality of rubber products should be enhanced adapted to consumer demand. This study aims to determine whether the quality of the rubber produced in PTPN IX (Persero Garden Batujamus/Kerjoarum still within the control or not. This study uses time series data, in the form of rubber production data during March 2012 - February 201, that were analyzed descriptively using Control p Chart Analysis. Control p Chart describe the proportion of production damage that can be tolerated as a tool for statistical Control p Chart Application as Quality Control Tools for Rubber Production in PTPN IX Batujamus/Kerjoarum process control. This study shows that the quality of the rubber produced by PTPN IX (Persero Garden Batujamus/ Kerjoarum is out of the control. The Control p Chart proves that there are still many points that are outside the production control line. The production domination of the third RSS type (RSS 3 cause this problem, so that the profit and the efficiency of the company can be increased if the RSS 3 product can be controlled and be changed with the production of RSS 1.

European Cosmic Ray Symposium

CERN Multimedia

Pattison,B

1992-01-01

13me Symposium qui se déroule du 27 au 31 juillet pour la première fois au Cern. Brian Pattison ouvre la cérémonie et donne la parole à Dr.Ugland (qui représente le DG C.Rubbia excusé) et d'autres intervenants

PREFACE: Fourth International Symposium on Atomic Technology

Science.gov (United States)

Okada, Shigefumi

2010-04-01

The International Symposium on Atomic Technology (ISAT) is held every year. The 4th Symposium (ISAT-4) was held on November 18-19, 2009 at the Seaside Hotel MAIKO VILLA KOBE, Kobe City, Japan presided by the "Atomic Technology Project". The ISAT-4 symposium was intended to offer a forum for the discussion on the latest progress in the atomic technologies. The symposium was attended by 107 delegates. There were 10 invited and 6 oral presentations. The number of poster presentations was 69. From all the contributions, 22 papers selected through review process are contained in this volume. The "Atomic Technology Project" was started in 2006 as a joint project of three institutions; (1) the Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University (CAMT), (2) the Tsukuba Research Center for Interdisciplinary Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba (TIMS) and (3) the Polyscale Technology Research Center, Research Institute for Science and Technology, Tokyo University of Science (PTRC), each of which were independently pursuing nano-technologies and was developing atomic scale operation and diagnostics, functional materials, micro processing and device. The project is funded by the Ministry of Education, Culture, Sports, Science and Technology of Japan. The goal of the project is to contribute to the development of atomic-scale science and technologies such as functional molecules, biomaterials, and quantum functions of atomic-scale structures. Shigefumi Okada Conference Chair Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita-city, Osaka 565-0871, Japan. Conference photograph Kobe photograph

SASP - Symposium on atomic, cluster and surface physics `94

Energy Technology Data Exchange (ETDEWEB)

Maerk, T D; Schrittwieser, R; Smith, D

1994-12-31

This international symposium (Founding Chairman: W. Lindinger, Innsbruck) is one in a continuing biennial series of conferences which seeks to promote the growth of scientific knowledge and its effective exchange among scientists in the field of atomic, molecular, cluster and surface physics and related areas. The symposium deals in particular with interactions between ions, electrons, photons, atoms, molecules, and clusters and their interactions with surfaces. (author).

10. Symposium energy and environment - responsibility for the future

International Nuclear Information System (INIS)

2003-01-01

The symposium discussed important aspects relating to the subject of energy and environment. The detailed and well-funded lectures and statements were received with great interest by the 120 attendants. The discussion focused on problems of power generation and consumption, increased shares of renewable energy sources, ethical and theological questions. The symposium received funds from Deutsche Bundesstiftung Umwelt and was well accepted by the press [de

Proceedings of the symposium Actinides 2006 - Basic Science, Applications and Technology

International Nuclear Information System (INIS)

Blobaum, Kerri J.M.; Chandler, Elaine A.; Havela, Ladislav; Maple, M. Brian; Neu, Mary P.

2007-01-01

These proceedings from the September 2006 symposium includes papers presented on experimental and modeling work with the intention of broadening understanding of the field of actinide research. Actinides have gained attention recently because of their roles in the threat of nuclear terrorism (e.g., 'dirty bombs') and the use of nuclear power to offset fossil fuel consumption. Actinide science is the study of the elements with atomic numbers in the range of 90 to 103, which includes uranium and plutonium. Beyond the well-known nuclear reactions of these heavy radioactive metals, the large electron clouds with 5f electrons in the outer shell yield fascinating and complex chemistries, crystal structures, and physical properties. Traditionally, actinide research has been divided among three scientific disciplines: chemistry (nuclear chemistry and radiochemistry); physics (condensed matter physics and electronic structure); and materials science (metallurgy). Modern actinide research, however, has become an interdisciplinary blend of these traditional fields, and it also incorporates developing fields such as environmental chemistry and superconductivity. Improved scientific understanding of actinides is needed for development of materials for actinide detection and nuclear fuels, and for safer management of nuclear waste. Recently, there has been a resurgence of actinide science at national laboratories and universities. The current multidisciplinary approach to actinide science lays the groundwork for understanding the connection between the 5f electronic structure and observed chemical reactions and physical properties such as structural phase transformations and novel ground states. This work provides many opportunities for new researchers in actinide science. These proceedings gather 25 selected papers among the 53 presentations given at this symposium

Proceedings Forest & Field Fuels Symposium

Energy Technology Data Exchange (ETDEWEB)

None

1978-07-01

The purpose of the symposium is to examine two specific renewable resources, forest and field fuels, to pinpoint areas where funding of RD&D would be effective in expanding their marketability and use as substitutes for imported oil.

Research symposium proceedings. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1991-12-31

THE research symposium was organized to present the cutting edge research for PET by individuals from leading institutions throughout the world. The Institute for Clinical PET (ICP) has focused its annual meeting on the clinical applications of PET.

Finding the Motivation: The Evolution of a Faculty Scholarship Symposium

Science.gov (United States)

Pifer, Meghan J.; Reisboard, Dana; Staulters, Mimi; Li, Xiaobao; Gozza-Cohen, Mary; McHenry, Nadine; Schaming, Susan; Gilio, Brenda

2014-01-01

This article describes the evolution of a faculty scholarship symposium within the school of education at a regional comprehensive university. The article outlines the initial structure and goals of the symposium as well as the development of the model over time. The influence of leadership, culture, and individual goals and backgrounds are…

Functional and Logic Programming - 14th International Symposium (FLOPS 2018)

DEFF Research Database (Denmark)

This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018......This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018...

Collateral patient doses in the Varian 21iX radiotherapy Linac

International Nuclear Information System (INIS)

Barquero, R.; Castillo, A. del

2008-01-01

Full text: The radiotherapy aim is to irradiate the patient tumor cells while the doses in healthy tissue remains as low as possible. Nevertheless, when high photon energy accelerators are used, collateral undesired photon and neutron doses are always implied during the treatments and became more important with the new accelerators and techniques as IMRT. To assess secondary cancer risk outside the treatment volume as a long-term medical consequence of treatments, the total doses received by each patient outside the primary field during his treatment must be estimated. To achieve this purpose photon and neutron dose equivalents Hp(10) and H*(10) has been measured in a new Varian 21iX with maximum photon energy of 15 MV placed recently in our radiotherapy department. Three devices: 1) a neutron dose rate meter BERTHOLD LB 4111 calibrated recently in the German PTB laboratory, 2) a calibrated environmental pressurized photon ionization chamber (IC) VICTOREEN 450-PI n/s 1020, and 3) a calibrated personal electronic photon dosimeter GAMMACOM 4200M, were placed above the treatment couch outside the primary field while the Varian 21iX reference test were done. In particular the photon and neutron doses in the couch were measured while a water phantom was irradiated during automatic beam data acquisition for a 15 MV beam. A complete set of measurements changing field size are made. These 15 MV results are compared with data measured previously by thermoluminescence and bubble dosimeters in the same facility for an Elekta Precise and a Siemens KDS both with maximum photon energy of 18 MV. From this the benefits in the patient collateral doses of decreasing the maximum treatment photon energy are discussed. The patient doses obtained in the Varian 21iX had values that go from 80 to 800 uSv per treatment Gray. As the Varian 21iX therapy Linac is operated in pulsed mode with short pulse length the discussion of the results includes: 1. The correction of dead time in the GM

Fe IX CALCULATIONS FOR THE SOLAR DYNAMICS OBSERVATORY

International Nuclear Information System (INIS)

Foster, Adam R.; Testa, Paola

2011-01-01

New calculations of the energy levels, radiative transition rates, and collisional excitation rates of Fe IX have been carried out using the Flexible Atomic Code, paying close attention to experimentally identified levels and extending existing calculations to higher energy levels. For lower levels, R-matrix collisional excitation rates from earlier work have been used. Significant emission is predicted by these calculations in the 5f-3d transitions, which will impact analysis of Solar Dynamics Observatory Atmospheric Imaging Assembly observations using the 94 A filter.

Symposium in Honour of T.A. Springer

CERN Document Server

Hesselink, Wim; Kallen, Wilberd; Strooker, Jan

1987-01-01

From 1-4 April 1986 a Symposium on Algebraic Groups was held at the University of Utrecht, The Netherlands, in celebration of the 350th birthday of the University and the 60th of T.A. Springer. Recognized leaders in the field of algebraic groups and related areas gave lectures which covered wide and central areas of mathematics. Though the fourteen papers in this volume are mostly original research contributions, some survey articles are included. Centering on the Symposium subject, such diverse topics are covered as Discrete Subgroups of Lie Groups, Invariant Theory, D-modules, Lie Algebras, Special Functions, Group Actions on Varieties.

Bianchi Type-IX viscous fluid cosmological model in general relativity

Indian Academy of Sciences (India)

the de-Sitter universe, the Taub-NUT solutions etc. are of Bianchi Type-IX space- times. In these models, neutrino viscosity does not guarantee isotropy at the present ..... The model (2.11) starts with a big-bang at T = 0 where α > 0 and m < 2, and the expansion in the model decreases as time increases. The expansion in the ...

Proceedings of the Symposium on Nuclear Energy and Environment

International Nuclear Information System (INIS)

1993-01-01

The symposium was organized and set against the background of the industry is traditional concern for safety and the environment. The purpose of the symposium was to contribute further to the international bank of knowledge by describing recent experience, especially of Latin-America countries, in adopting, adapting and developing the practices of the industry for ensuring safety and compatibility with the environment. In the cause of four days, june 28 to july 1993, thirty five papers were presented, besides fourteen articles were arranged in the following sessions: invited speakers, safety and risk assessment, environmental protection, waste management and disposal emergency planning and public acceptance and health aspects. The Latin American Section of the American Nuclear Society convened the symposium in the city of Rio de Janeiro, Brazil. (B.C.A.)

Comparison of adenovirus fiber, protein IX, and hexon capsomeres as scaffolds for vector purification and cell targeting

International Nuclear Information System (INIS)

Campos, Samuel K.; Barry, Michael A.

2006-01-01

The direct genetic modification of adenoviral capsid proteins with new ligands is an attractive means to confer targeted tropism to adenoviral vectors. Although several capsid proteins have been reported to tolerate the genetic fusion of foreign peptides and proteins, direct comparison of cell targeting efficiencies through the different capsomeres has been lacking. Likewise, direct comparison of with one or multiple ligands has not been performed due to a lack of capsid-compatible ligands available for retargeting. Here we utilize a panel of metabolically biotinylated Ad vectors to directly compare targeted transduction through the fiber, protein IX, and hexon capsomeres using a variety of biotinylated ligands including antibodies, transferrin, EGF, and cholera toxin B. These results clearly demonstrate that cell targeting with a variety of high affinity receptor-binding ligands is only effective when transduction is redirected through the fiber protein. In contrast, protein IX and hexon-mediated targeting by the same set of ligands failed to mediate robust vector targeting, perhaps due to aberrant trafficking at the cell surface or inside targeted cells. These data suggest that vector targeting by genetic incorporation of high affinity ligands will likely be most efficient through modification of the adenovirus fiber rather than the protein IX and hexon capsomeres. In contrast, single-step monomeric avidin affinity purification of Ad vectors using the metabolic biotinylation system is most effective through capsomeres like protein IX and hexon

PREFACE: Nobel Symposium 141: Qubits for Future Quantum Information Nobel Symposium 141: Qubits for Future Quantum Information

Science.gov (United States)

Claeson, Tord; Delsing, Per; Wendin, Göran

2009-12-01

correction, have yet to be solved. It has been predicted that quantum computers will be able to perform certain complicated computations or simulations in minutes or hours instead of years as with present computers. So far there exist very few useful quantum algorithms; however there is hope that the development of these will be stimulated once there is a breakthrough in hardware. Remarkable progress has been made in quantum engineering and quantum measurements, but a large scale quantum computer is still far off. Quantum communication and cryptography are much closer to the market than a quantum computer. The development of quantum information has meant a large push in the field of quantum physics, that previously could only be studied in the microscopic world. Artificial atoms, realized by circuit technology and mimicking the properties of 'natural' atoms, are one example of the new possibilities opened up by quantum engineering. Several different types of qubits have been suggested. Some are based upon microscopic entities, like atoms and ions in traps, or nuclear spins in molecules. They can have long coherence times (i.e. a long period allowing many operations, of the order of 10 000, to be performed before the state needs to be refreshed) but they are difficult to integrate into large systems. Other qubits are based upon solid state components that facilitate integration and coupling between qubits, but they suffer from interactions with the environment and their coherent states have a limited lifetime. Advanced experiments have been performed with superconducting Josephson junctions and many breakthroughs have been reported in the last few years. They have an advantage in the inherent coherence of superconducting Cooper pairs over macroscopic distances. We chose to focus the Nobel Symposium on Qubits for Future Quantum Information on superconducting qubits to allow for depth in discussions, but at the same time to allow comparison with other types of qubits that may

VIII international electric vehicle symposium

Energy Technology Data Exchange (ETDEWEB)

1986-01-01

The proceedings from the symposium are presented. Major topics discussed include: battery technology, powertrains; hybrid vehicles, marketing and economics, propulsion, and electric vehicle design and performance. Each paper has been separately indexed for inclusion in the Energy Data Base.

Ethics and Integrity. Symposium 27. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

Science.gov (United States)

2000

This packet contains three papers on ethics and integrity from a symposium on human resource development (HRD). The first paper, "Factors Influencing Ethical Resolution Efficacy: A Model for HRD Practitioners" (Kimberly S. McDonald), proposes a model of ethical resolution efficacy for HRD practitioners. The model suggests that factors related to…

Issues of HRD. Symposium.

Science.gov (United States)

2002

This document contains three papers from a symposium on issues of human resource development (HRD). "The Complex Roots of Human Resource Development" (Monica Lee) discusses the roots of HRD within the framework of the following views of management: (1) classic (the view that managers must be able to create appropriate rules and…

Atlantic white cedar: ecology, restoration, and management: Proceedings of the Arlington Echo symposium

Science.gov (United States)

Philip Sheridan

2005-01-01

A symposium was held on the globally threatened and coastally restricted tree species, Atlantic white-cedar (Chamaecyparis thyoides (L) B.S.P.) at the Arlington Echo Outdoor Education Center, Millersville, MD, in June 2003. The theme of the symposium was “Uniting Forces for Action,” and participants in the symposium came from throughout the range of this species, from...

PREFACE: 9th National Symposium on Polymeric Materials (NSPM 2009)

Science.gov (United States)

Ali, Aidy; Salit, Sapuan

2010-07-01

NSPM 2009 is the formal proceedings of the 9th National Symposium on Polymeric Materials held in Residence Hotel Uniten Bangi on 14-16 December 2009. It is also organised with The Plastics and Rubber Institute Malaysia PRIM. The symposium proceedings consists of 94 papers covering a large number of issues on experimental and analytical studies of polymeric materials. The objectives of the symposium are to review the state-of-the art, present and latest findings and exchange ideas among engineers, researchers and practitioners involved in this field. We strongly hope the outcomes of this symposium will stimulate and enhanced the progress of experimental and analytical studies on polymeric materials as well as contribute to the fundamental understanding in related fields. After careful refereeing of all manuscripts, 15 papers were selected for publications in this issue. Another 20 papers were selected for publication in Pertanika Journal of Science and Technology (PJST). The content of the material and its rapid dissemination was considered to be more important than its form. We are grateful to all the authors for their papers and presentations in this symposium. They are also the ones who help make this symposium possible through their hard work in the preparation of the manuscripts. We would also like to offer our sincere thanks to all the invited speakers who came to share their knowledge with us. We would also like to acknowledge the untiring efforts of the reviewers, research assistants and students in meeting deadlines and for their patience and perseverance. We are indeed honoured to associate this event with Department of Mechanical and Manufacturing, and Faculty of Engineering, Universiti Putra Malaysia. Finally, we appreciate the sponsor support provided by Faculty of Engineering, The Plastics and Rubber Institute Malaysia (PRIM) and PETRONAS Malaysia. Thank you all. Editors: Aidy Ali and S M Sapuan

7th international symposium on internal combustion diagnostics. Proceedings; 7. Internationales Symposium fuer Verbrennungsdiagnostik. Beitraege

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

At one time combustion pressure indicating was the ''trigger'' for this symposium, and today it still serves as the basis for continued investigation of combustion phenomena. It now finds application throughout the development process, as more sophisticated analysis of conventional signals is possible. Understanding of localized combustion phenomena is substantially simplified by means of optical diagnostic methods, the application of which has reached a certain level of standardization. The presentations will cover specific topics including fuel spray analysis, ignition events and information about gas mixtures. The comparison and combination of results from measurement and simulation shed light on the complex processes in the combustion chamber. What's more, the linkage of two complementary methods offers substantial cost savings through reductions in test hardware and shorter development times. Focused application of all of the available tools allows us better to understand combustion processes, recognize the influential parameters and derive control algorithms. The latter are subsequently to be found in engines that fulfill both regulatory requirements and customer expectations. So it is that the symposium captures the current state of the art in combustion diagnostics through a combination of indicating, optical diagnostics and simulation, and offers both the methodology expert and the engine developer the ideal platform for discussion of today's issues - and to form their own opinions on them. Anyone wanting to keep up to date in this continuously developing and ever more complex area of activity certainly can't afford to miss our symposium. (orig.)

Proceedings of the symposium on molecular biology and radiation protection

International Nuclear Information System (INIS)

Marko, A.M.

1996-02-01

The symposium on molecular biology and radiation protection was organized in sessions with the following titles: Radiation protection and the human genome; Molecular changes in DNA induced by radiation; Incidence of genetic changes - pre-existing, spontaneous and radiation-induced; Research directions and ethical implications. The ten papers in the symposium have been abstracted individually

Proceedings of the symposium on molecular biology and radiation protection

Energy Technology Data Exchange (ETDEWEB)

Marko, A M [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection; Myers, D K; Atchison, R J [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection. Secretariat; Gentner, N E [Atomic Energy of Canada Ltd., Chalk River, ON (Canada)

1996-02-01

The symposium on molecular biology and radiation protection was organized in sessions with the following titles: Radiation protection and the human genome; Molecular changes in DNA induced by radiation; Incidence of genetic changes - pre-existing, spontaneous and radiation-induced; Research directions and ethical implications. The ten papers in the symposium have been abstracted individually.

Nuclear fusion: Pursuing the Soft [Symposium on fusion technology] option

International Nuclear Information System (INIS)

Kenward, M.

1991-01-01

Fusion research has come a long way since the fusion community held the first Symposium on fusion technology (Soft) in Britain 30 years ago. Some of the recent achievements of the Jet project are reported from this year's symposium, the 16th in the series, held in London at the beginning of September. (author)

Report. First international symposium on innovating mining systems

Energy Technology Data Exchange (ETDEWEB)

Blackwood, R L

1985-01-01

The author presents a summary of proceedings of the First International Symposium on Innovative Mining Systems held at Massachusetts Institute of Technology, USA 4-5 November 1985, together with some comments on the conclusions and discussion throughout. The Symposium agenda included the following (i) Symposium intentions and expectations; (ii) International; (iii) Developments in safety; (iv) Overview of current major research and trends; (v) Panel discussion: Mechanisms for industrial and international collaboration; (vi) Closing remarks; (vii) Review of innovations: university programs; (viii) Review of selected mine operator programs and needs; Review of equipment innovations; capabilities and trends in areas of mining equipment and robotics; Concurrent sessions: operations and manufacturing. A series of workshops was also held, the titles of which were as follows: (i) Establishment of research network; (ii) Entry development-machine excavation; (iii) Sensing, monitoring, diagnostics, artificial intelligence; (iv) Remote control, automation, mining systems; (v) Computer aided design, simulation, system development; (vi) Surface mining; (vii) Rock breakage.

Crafoord Symposium on Magnetospheric Physics : Achievements and Prospects

CERN Document Server

Fälthammar, C-G

1990-01-01

This book contains the proceedings of the 1989 Crafoord Symposium organized by the Royal Swedish Academy of Sciences. The scientific field for the Crafoord Prize of 1989 was decided in 1988 by the Academy to be Magnetospheric Physics. On September 27,1989 the Academy awarded the 1989 Crafoord Prize to Professor J. A. Van Allen, Iowa City, USA "for his pioneer work in space research, in particular for the discovery of the high energy charged particles that are trapped in the Earth's magnetic field and form the radiation belts -often called the Van Allen belts - around the Earth". The subject for the Crafoord Symposium, which was held on September 28-29 at the Royal Swedish Academy of Sciences in Stockholm, was Magnetospheric Physics, Achievements and Prospects. Some seventy of the world's leading scientists in magnetospheric physics (see list of participants) were invited to the Symposium. The program contained only invited papers. After the ?resentation of the Crafoord Prize Laureate, Prof. J . A. Van Allen, ...

2nd International Industrial Symposium on the Supercollider

CERN Document Server

IISSC; Supercollider 2

1990-01-01

The Second International Industrialization Symposium on the Supercollider, IISSC, was held in Miami Beach Florida on March 14-16, 1990. It was an even bigger and more successful meeting than our ftrst in New Orleans in 1989. There were 691 attendees and 75 exhibitors. The enthusiasm shown by both the speakers and the audience was exhilarating for all attendees. The symposium again brought together the physicists and engineers designing the machine, the industrial organizations supporting the design and construction, the education community, and the governmental groups responsible for the funding and management of the SSC project. We believe it is this unique rnix which makes this particular meeting so valuable. The theme of this symposium was "The SSC-Americas Research Partnership" and the varied presentations throughout the meeting high-lighted that theme. The keynote speakers were: Dr. Roy Schwitters, Director of the SSC Mr. Paul F. Orefftce, Chairman of the Board of Dow Chemical Company Honorable W. Hinson...

Proceedings of the High Consequence Operations Safety Symposium

Energy Technology Data Exchange (ETDEWEB)

1994-12-01

Many organizations face high consequence safety situations where unwanted stimuli due to accidents, catastrophes, or inadvertent human actions can cause disasters. In order to improve interaction among such organizations and to build on each others` experience, preventive approaches, and assessment techniques, the High Consequence Operations Safety Symposium was held July 12--14, 1994 at Sandia National Laboratories, Albuquerque, New Mexico. The symposium was conceived by Dick Schwoebel, Director of the SNL Surety Assessment Center. Stan Spray, Manager of the SNL System Studies Department, planned strategy and made many of the decisions necessary to bring the concept to fruition on a short time scale. Angela Campos and about 60 people worked on the nearly limitless implementation and administrative details. The initial symposium (future symposia are planned) was structured around 21 plenary presentations in five methodology-oriented sessions, along with a welcome address, a keynote address, and a banquet address. Poster papers addressing the individual session themes were available before and after the plenary sessions and during breaks.

Carbonic Anhydrase IX is Not a Predictor of Outcomes in Non-Metastatic Clear Cell Renal Cell Carcinoma - A Digital Analysis of Tissue Microarray

Directory of Open Access Journals (Sweden)

Marcelo Zerati

2013-07-01

Full Text Available Introduction The knowledge about the molecular biology of clear cell renal cell carcinoma (ccRCC is evolving, and Carbonic Anhydrase type IX (CA-IX has emerged as a potential prognostic marker in this challenging disease. However, most of the literature about CA-IX on ccRCC comes from series on metastatic cancer, with a lack of series on non-metastatic cancer. The objective is to evaluate the expression of CA-IX in a cohort of non-metastatic ccRCC, correlating with 1 overall survival, and 2 with established prognostic parameters (T stage, tumor size, Fuhrman nuclear grade, microvascular invasion and peri-renal fat invasion. Materials and Methods This is a retrospective cohort study. We evaluated 95 patients with non-metastatic clear cell renal cell carcinoma, as to the expression of CA-IX. The analyzed parameters where: overall survival (OS, TNM stage, tumor size (TS, Fuhrman nuclear grade (FNG, microvascular invasion (MVI, peri-renal fat invasion (PFI. We utilized a custom built tissue microarray, and the immunoexpression was digitally quantified using the Photoshop® software. Results: Th e mean follow-up time was 7.9 years (range 1.9 to 19.5 years. The analysis of CA-IX expression against the selected prognostic parameters showed no correlation. The results are as follows: Overall survival (p = 0.790; T stage (p = 0.179; tumor size (p = 0.143; grouped Fuhrman nuclear grade (p = 0.598; microvascular invasion (p = 0.685, and peri-renal fat invasion (p = 0.104. Conclusion Carbonic anhydrase type IX expression does not correlate with overall survival and conventional prognostic parameters in non-metastatic clear cell renal cell carcinoma.

44th Aerospace Mechanisms Symposium

Science.gov (United States)

Boesiger, Edward A. (Compiler)

2018-01-01

The Aerospace Mechanisms Symposium (AMS) provides a unique forum for those active in the design, production and use of aerospace mechanisms. A major focus is the reporting of problems and solutions associated with the development and flight certification of new mechanisms.

Kinetics and comparison of δ-aminolevulinic-acid-induced endogenous protoporphyrin-IX in single cell by steady state and multiphoton fluorescence imaging

Science.gov (United States)

Ganesan, Singaravelu; Elangovan, Masilamani; Periasamy, Ammasi

2001-04-01

Photodynamic Therapy has emerged as a new modality in the treatment of various nonmalignant and malignant diseases. It involves the systemic administration of tumor specific photo-sensitizers with the subsequent application of visible light. This combination causes the generation of cytotoxic species, which damage sensitive targets, producing cell injury and tumor destruction. Although, photofrin is the only photosensitizer currently approved for PDT and tumor detection, its concomitant cutaneous photosensitization poses a significant problem. Hence, δ-aminoleuvulinic acid (δ-ALA) a precursor for the endogenous production of Protoporphyrin IX, through heme biosynthesis pathway, has gained significant importance in the Photodynamic Therapy. Though δ-ALA is present naturally in the cells, exogenous δ-ALA helps to synthesis more of PpIX in the tumor cells, as the fast growing tumor cells take up the administered δ-ALA more than the normal cells. Based on these facts, many invasive studies have been reported on the kinetics of δ-ALA at cellular level by chemical extraction of PpIX from the cells. In the present study we have studied the kinetics of δ-ALA induced PpIX fluorescence from Hela cells by perchloric/Methanol extraction method. However, the amount of PpIX synthesized in the cells at different point of incubation time by noninvasive methods has not been reported. Hence we have also used a noninvasive technique of measuring the kinetics δ-ALA induced PPIX fluorescence from Hela, an epithelial cell derived from human cervical cancer by both single photon (steady state) and multi photon excitation. From the studies it is observed that the δ-ALA induced PpIX is more at 2 hours incubation time for 2 mM of δ-ALA concentration. Further, it is observed that with steady state fluorescence imaging method, the excitation light itself cause the Photodynamic damage, due to the prolonged exposure of the cells than in multi photon excitation, leading to the rounding

Comparison between two portable devices for widefield PpIX fluorescence during cervical intraepithelial neoplasia treatment

Science.gov (United States)

Carbinatto, Fernanda M.; Inada, Natalia Mayumi; Lombardi, Welington; Cossetin, Natália Fernandez; Varoto, Cinthia; Kurachi, Cristina; Bagnato, Vanderlei Salvador

2015-06-01

The use of portable electronic devices, in particular mobile phones such as smartphones is increasing not only for all known applications, but also for diagnosis of diseases and monitoring treatments like topical Photodynamic Therapy. The aim of the study is to evaluate the production of the photosensitizer Protoporphyrin IX (PpIX) after topical application of a cream containing methyl aminolevulinate (MAL) in the cervix with diagnosis of Cervical Intraepithelial Neoplasia (CIN) through the fluorescence images captured after one and three hours and compare the images using two devices (a Sony Xperia® mobile and an Apple Ipod®. Was observed an increasing fluorescence intensity of the cervix three hours after cream application, in both portable electronic devices. However, because was used a specific program for the treatment of images using the Ipod® device, these images presented better resolution than observed by the Sony cell phone without a specific program. One hour after cream application presented a more selective fluorescence than the group of three hours. In conclusion, the use of portable devices to obtain images of PpIX fluorescence shown to be an effective tool and is necessary the improvement of programs for achievement of better results.

77 FR 4544 - CPSC Symposium on Phthalates Screening and Testing Methods

Science.gov (United States)

2012-01-30

... Screening and Testing Methods AGENCY: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: The... symposium on phthalates screening and testing methods. The symposium will be held at the CPSC's National... submit comments, identified by Docket No. CPSC-2012-0008, by any of the following methods: Electronic...

Evaluation of a gadolinium-based nanoparticle (AGuIX) for contrast-enhanced MRI of the liver in a rat model of hepatic colorectal cancer metastases at 9.4 tesla

Energy Technology Data Exchange (ETDEWEB)

Fries, P.; Morr, D.; Mueller, A.; Massmann, A.; Seidel, R.; Schneider, G.; Buecker, A. [Saarland University Medical Center, Homburg (Germany). Clinic of Diagnostic and Interventional Radiology; Lux, F.; Tillement, O. [Universite Claude Bernard, Lyon (France). Laboratoire de Physico-Chimie des Materiaux Luminescents; Schaefer, T. [Saarland University Medical Center, Homburg (Germany). Dept. of General, Visceral and Pediatric Surgery; Menger, M.D. [Saarland University Medical Center, Homburg (Germany). Inst. for Clinical and Experimental Surgery

2015-12-15

The aim of this study was to compare a Gd-based nanoparticle (AGuIX) with a standard extracellular Gd-based contrast agent (Gd-DOTA) for MRI at 9.4 T in rats with hepatic colorectal cancer metastases. 12 rats with hepatic metastases were subjected to MRI using a 9.4 T animal scanner. T1w self-gated FLASH sequences (TR/TE=45/2.5 ms, alpha = 45 , TA=1: 23 min, FOV=5.12 x 5.12 cm{sup 2}, matrix = 256 x 256) were acquired before and at 10 time points after contrast injection. Each animal received 0.1 mmol/kg BW Gd-DOTA i.v. 2 days later AGuIX was applied at 0.01 mmol/kg BW (representing equal Gd doses). The SNR of normal liver (SNRliver), hyper- and hypoenhancing parts of tumors (SNRtumor, hyperenh/SNRtumor, hypoenhanc), erector spinae muscle (SNRmuscle), CNR and lesion enhancement (LE) were calculated based on ROI measurements. Mean SNRliver (Gd-DOTA: 14.6 ± 0.7; AGuIX: 28.2 ± 2.6, p < 0.001), SNRtumor, hyperenhanc (Gd-DOTA: 18.6 ± 1.2; AGuIX: 29.6 ± 2.8, p < 0.001), SNRtumor, hypoenhanc (Gd-DOTA: 12.0 ± 0.7; AGuIX: 15.4 ± 0.7, p < 0.001), SNRmuscle (Gd-DOTA: 12.3 ± 0.3; AGuIX: 14.0 ± 0.7, p < 0.001), mean CNR (Gd-DOTA: -2.5 ± 0.2; AGuIX: -7.5 ± 1.0, p < 0.001) and LE (Gd-DOTA: 3.8 ± 0.7; AGuIX: 14.9 ± 2.8, p=0.001) were significantly higher using AGuIX. Regardless of the larger molecular size, AGuIX demonstrates an early peak enhancement followed by a continuous washout. AGuIX provides better enhancement at 9.4 T compared to Gd-DOTA for equal doses of applied Gd. This is based on the molecule structure and the subsequent increased interaction with protons leading to a higher relaxivity. AGuIX potentially ameliorates the conspicuity of focal liver lesions and may improve the sensitivity in diagnostic imaging of malignant hepatic tumors.

Evaluation of a gadolinium-based nanoparticle (AGuIX) for contrast-enhanced MRI of the liver in a rat model of hepatic colorectal cancer metastases at 9.4 tesla

International Nuclear Information System (INIS)

Fries, P.; Morr, D.; Mueller, A.; Massmann, A.; Seidel, R.; Schneider, G.; Buecker, A.; Lux, F.; Tillement, O.; Schaefer, T.; Menger, M.D.

2015-01-01

The aim of this study was to compare a Gd-based nanoparticle (AGuIX) with a standard extracellular Gd-based contrast agent (Gd-DOTA) for MRI at 9.4 T in rats with hepatic colorectal cancer metastases. 12 rats with hepatic metastases were subjected to MRI using a 9.4 T animal scanner. T1w self-gated FLASH sequences (TR/TE=45/2.5 ms, alpha = 45 , TA=1: 23 min, FOV=5.12 x 5.12 cm 2 , matrix = 256 x 256) were acquired before and at 10 time points after contrast injection. Each animal received 0.1 mmol/kg BW Gd-DOTA i.v. 2 days later AGuIX was applied at 0.01 mmol/kg BW (representing equal Gd doses). The SNR of normal liver (SNRliver), hyper- and hypoenhancing parts of tumors (SNRtumor, hyperenh/SNRtumor, hypoenhanc), erector spinae muscle (SNRmuscle), CNR and lesion enhancement (LE) were calculated based on ROI measurements. Mean SNRliver (Gd-DOTA: 14.6 ± 0.7; AGuIX: 28.2 ± 2.6, p < 0.001), SNRtumor, hyperenhanc (Gd-DOTA: 18.6 ± 1.2; AGuIX: 29.6 ± 2.8, p < 0.001), SNRtumor, hypoenhanc (Gd-DOTA: 12.0 ± 0.7; AGuIX: 15.4 ± 0.7, p < 0.001), SNRmuscle (Gd-DOTA: 12.3 ± 0.3; AGuIX: 14.0 ± 0.7, p < 0.001), mean CNR (Gd-DOTA: -2.5 ± 0.2; AGuIX: -7.5 ± 1.0, p < 0.001) and LE (Gd-DOTA: 3.8 ± 0.7; AGuIX: 14.9 ± 2.8, p=0.001) were significantly higher using AGuIX. Regardless of the larger molecular size, AGuIX demonstrates an early peak enhancement followed by a continuous washout. AGuIX provides better enhancement at 9.4 T compared to Gd-DOTA for equal doses of applied Gd. This is based on the molecule structure and the subsequent increased interaction with protons leading to a higher relaxivity. AGuIX potentially ameliorates the conspicuity of focal liver lesions and may improve the sensitivity in diagnostic imaging of malignant hepatic tumors.

Proceedings of the 2009 annual symposium on nuclear data. NDS2009

International Nuclear Information System (INIS)

Koura, Hiroyuki; Chiba, Satoshi

2010-12-01

The annual nuclear data symposium, organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) was held at Ricotti, Tokai, on Nov. 26 and 27, 2009 in cooperation with Advanced Science Research Center of JAEA and under financial support from North-Kanto Branch of AESJ. The symposium was devoted for discussions and presentations of research results in wide variety of fields related to nuclear data, including 3 tutorial talks. Talks as well as posters presented at the symposium aroused lively discussions among approximately 90 participants. This report contains 17 papers submitted from the talkers and poster presenters. (author)

Proceedings of the 4th international symposium on material testing reactors

International Nuclear Information System (INIS)

Ishihara, Masahiro; Suzuki, Masahide

2012-03-01

This report is the Proceedings of the fourth International Symposium on Material Testing Reactors hosted by Japan Atomic Energy Agency (JAEA). The first symposium was held on 2008, at the Oarai Research and Development Center of JAEA, the second, 2009, Idaho National Laboratory (INL) of United States and the third 2010, Nuclear Research Institute (NRI) in Czech Republic to exchange information for deep mutual understanding of material testing reactors. The fourth symposium was originally scheduled to be held INVAP in Argentina. However, the aftermath of volcanic explosion at Chili forced the symposium to change place. Total 111 participants attended from Argentina, Belgium, France, Germany, Indonesia, Malasia, Korea, South Africa, Switzerland, the United State and Japan. This symposium addressed the general topics of 'status and future plan of material testing reactors', 'advancement of irradiation technology', 'expansion of industry use(RI)', 'facility, upgrade, aging management', 'new generation MTR', 'advancement of PIE technology', 'development of advanced driver fuel', and 'nuclear human resource development(HRD) for next generation', and 39 presentations were made. Furthermore, three topics, 'Necessity of cooperation for Mo-99 production by (n,gamma) reaction', 'Necessity of standardization of irradiation technology' and 'Conceptual design of next generation materials testing reactor by collaboration', were selected and discussed. (author)

Proceedings of the 4th international symposium on material testing reactors

Energy Technology Data Exchange (ETDEWEB)

Ishihara, Masahiro; Suzuki, Masahide [Japan Atomic Energy Agency, Oarai Research and Development Center, Oarai, Ibaraki (Japan)

2012-03-15

This report is the Proceedings of the fourth International Symposium on Material Testing Reactors hosted by Japan Atomic Energy Agency (JAEA). The first symposium was held on 2008, at the Oarai Research and Development Center of JAEA, the second, 2009, Idaho National Laboratory (INL) of United States and the third 2010, Nuclear Research Institute (NRI) in Czech Republic to exchange information for deep mutual understanding of material testing reactors. The fourth symposium was originally scheduled to be held INVAP in Argentina. However, the aftermath of volcanic explosion at Chili forced the symposium to change place. Total 111 participants attended from Argentina, Belgium, France, Germany, Indonesia, Malasia, Korea, South Africa, Switzerland, the United State and Japan. This symposium addressed the general topics of 'status and future plan of material testing reactors', 'advancement of irradiation technology', 'expansion of industry use(RI)', 'facility, upgrade, aging management', 'new generation MTR', 'advancement of PIE technology', 'development of advanced driver fuel', and 'nuclear human resource development(HRD) for next generation', and 39 presentations were made. Furthermore, three topics, 'Necessity of cooperation for Mo-99 production by (n,gamma) reaction', 'Necessity of standardization of irradiation technology' and 'Conceptual design of next generation materials testing reactor by collaboration', were selected and discussed. (author)

Proceedings of the 10th symposium on advanced photon research

International Nuclear Information System (INIS)

2010-06-01

The 10th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on October 21 - 22, 2009. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. The 38 of the presented papers are indexed individually. (J.P.N.)

Proceedings of the 11th symposium on advanced photon research

International Nuclear Information System (INIS)

2011-03-01

The 11th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on June 24 - 25, 2010. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. The 29 of the presented papers are indexed individually. (J.P.N.)

Proceedings of the European Symposium on Pressure Equipment - ESOPE 2007

International Nuclear Information System (INIS)

2007-01-01

Every three years, and since thirty years, the AFIAP organizes a symposium where the experts and actors working in the field of pressure equipments, whether fixed or transportable, can meet and exchange on all developments related to their activity. What was at first called the 'National Congress on the technology of pressure components', and later the 'Study Days on pressure components', became since 2001 the 'European Symposium on Pressure Equipment' (ESOPE), so marking an opening to the European and International fields in a context marked by the application of the European Directives applicable to these equipments. The 2001 symposium was more particularly dedicated to the application of the directives harmonizing the construction of equipments, and the 2004 symposium was more particularly centred on the management of equipments in operation. For the ESOPE 2007 Symposium, the organizing committee wished to resume these two subjects under the aspects of the safety, the competitiveness, as well as the innovation. The plenary session of the last day will be completely dedicated to these subjects and will include a Panel discussion, where National and European authorities, representatives of manufacturers and users, as well as experts engaged in developments and new projects will express their views. These exchanges will also permit to answer the questions expressed by the participants. Every symposium has thus a main orientation, but shall also be the place of exchanges on the different subjects wished by the profession. The traditional technical sessions are consequently maintained: - Sessions on Design and Materials, - Sessions on Fabrication, - Sessions on Fitness for Service, and a special session dedicated to the National, European and International Codes is added, the afternoon of the first day. The plenary Opening session is also devoted to this last subject with lectures on the evolutions of European regulations, the orientations retained for pressure

Modifier activity of the protoporphyrin IX of the clastogenic damage induced by gamma radiation in Drosophila melanogaster; Actividad modificadora de la protoporfirina IX del dano clastogenico inducido por radiacion gamma en Drosophila melanogaster

Energy Technology Data Exchange (ETDEWEB)

Martinez A, G. [ININ, 52750 La Marquesa, Estado de Mexico (Mexico)

2007-07-01

It has been demonstrated that the copper sodium chlorophyllin (CCS) it is a potent inhibitor of the one genetic damage induced by physical or chemical agents in systems like: bacteria, Drosophila, rainbow trout and mammals. Nevertheless it has been observed that under certain conditions it promotes it. In the laboratory of Drosophila of the ININ evidences have been obtained that the CCS increases the percentage of lethal embryonic dominant and post-embryonic induced by gamma radiation. One of the probable causes of this effect promoter, is the oxidizer stress that it could cause the metallic center of the CCS. The objective of this investigation it was the evaluation of the inhibitory action of the protoporphyrin IX (PP-IX) of the genetic damage induced by gamma radiation in the germinal line of Drosophila melanogaster. For such effect it was used the lethal dominant test by means of two protocols: one in the one that the PP-IX or CCS was administered to the females and the other one to the males. Females of genotype y/y and males of the canton-S stump were used. In both cases the males were treated with 40 Gy of gamma radiation. Its were count the embryonic lethal dominant (L-E) and those post-embryonic (L-PE) of the F1. The results indicated that after the one pretreatment with PP-IX to the crossed females with males treaties increase the percentage of L-E (P {<=} 0.001) and it diminished that of L-PE (P {<=} 0.001) compared with the sucrose control more radiation, however when it was pretreated with CCS also it was observed an increment in the percentage of L-E (P {<=} 0.001), but it doesn't present effect on that of L-PE. In contrast, when the males were pretreated, it was observed that the PP-IX tends to increase those L-E, but diminished the L-PE (P {<=} 0.05), however when it was pretreated with CCS was observed that increased the percentage of L-E (P {<=} 0.001) but diminished that of L-PE (P {<=} 0.001). It was concluded that none of the two pigments

ICRS1, Proceedings of the First Radiation Shielding Symposium, Cambridge, UK 1958

International Nuclear Information System (INIS)

Goebelbecker, Hans-Juergen

2008-01-01

Description: The papers of the European Atomic Energy Society Symposium VI-58 on radiation shielding (ICRS1) held at Caius College, Cambridge England from 26 to 29 August 1958 are collected here for the first time in electronic form. This symposium was organised in connection with the Second Atoms for Peace Conference held in Geneva Held in Geneva from 1 to 13 September 1958. The Topics discussed covered gamma rays and neutron radiation; the Methods discussed were analytical approaches, semi-empirical Methods, simple computer codes, Monte Carlo method. Little quality nuclear data for shielding calculations was available and the presentations would concentrate on removal cross-sections and build-up factors. Experimental techniques in support to estimate the effective shielding properties of materials were discussed such as general experimental shielding techniques and experiments on neutron attenuation in different materials and on concrete as shield. Foil detectors for spectra measurements and determination of dose rates were mainly used. The typical issues addressed were gamma-heating, gamma spectra, neutron induced gammas, fission products gamma spectra, skyshine radiation and neutron ducts - streaming. Most participants were researchers from the naval and aeronautics sector

NATO Symposium entitled "Symposium on the Study of Motion Perception : Recent Developments and Applications"

CERN Document Server

Wagenaar, Willem; Leibowitz, Herschel

1982-01-01

From August 24-29, 1980 the international "Symposium on the Study of Motion Perception; Recent Developments and Applications", sponsored by NATO and organized by the editors of this book, was held in Veldhoven, the Netherlands. The meeting was attended by about eighty scholars, including psychologists, neurologists, physicists and other scientists, from fourteen different countries. During the symposium some fifty research papers were presented and a series of tutorial review papers were read and discussed. The research presentations have been published in a special issue of the international journal of psychonomics "Acta Psychologica" (Vol. 48, 1981). The present book is a compilation of the tutorial papers. The tutorials were arranged around early versions of the chapters now appearing in this book. The long discussions at the Veldhoven tutorial sessions resulted in extensive revisions of the texts prior to this publication. Unfortunately this led to a delay in publication, but we feel that this was justifi...

Proceedings of Waseda international symposium on fundamental physics. New perspectives in quantum physics

International Nuclear Information System (INIS)

Ohba, Ichiro; Aizawa, Yoji; Daishido, Tsuneaki; Kurihara, Susumu; Maeda, Kei-ichi; Nakazato, Hiromichi; Tasaki, Shuichi; Yuasa, Kazuya

2003-11-01

Waseda International Symposium on Fundamental Physics - New Perspectives in Quantum Physics - was held on November 12-15, 2002 at International Conference Hall (IBUKA HALL), Waseda University, Tokyo, Japan. This symposium was organized to provide an opportunity to verify fundamental physics attainments and to discuss new prospectives in quantum physics in the 21st century. These themes of the symposium were reexamined from all aspects in terms of important key words of the symposium, fundamental quantum theory, quantum coherence and decoherence, quantum chaos, time symmetry breaking, Bose-Einstein condensation and quantum information and computation. Separate abstracts were presented for 12 of the papers in this report. The remaining 40 were considered outside the subject scope of INIS. (J.P.N.)

PREFACE: International Symposium on Dynamic Deformation and Fracture of Advanced Materials (D2FAM 2013)

Science.gov (United States)

Silberschmidt, Vadim V.

2013-07-01

Intensification of manufacturing processes and expansion of usability envelopes of modern components and structures in many cases result in dynamic loading regimes that cannot be resented adequately employing quasi-static formulations of respective problems of solid mechanics. Specific features of dynamic deformation, damage and fracture processes are linked to various factors, most important among them being: a transient character of load application; complex scenarios of propagation, attenuation and reflection of stress waves in real materials, components and structures; strain-rate sensitivity of materials properties; various thermo-mechanical regimes. All these factors make both experimental characterisation and theoretical (analytical and numerical) analysis of dynamic deformation and fracture rather challenging; for instance, besides dealing with a spatial realisation of these processes, their evolution with time should be also accounted for. To meet these challenges, an International Symposium on Dynamic Deformation and Fracture of Advanced Materials D2FAM 2013 was held on 9-11 September 2013 in Loughborough, UK. Its aim was to bring together specialists in mechanics of materials, applied mathematics, physics, continuum mechanics, materials science as well as various areas of engineering to discuss advances in experimental and theoretical analysis, and numerical simulations of dynamic mechanical phenomena. Some 50 papers presented at the Symposium by researchers from 12 countries covered various topics including: high-strain-rate loading and deformation; dynamic fracture; impact and blast loading; high-speed penetration; impact fatigue; damping properties of advanced materials; thermomechanics of dynamic loading; stress waves in micro-structured materials; simulation of failure mechanisms and damage accumulation; processes in materials under dynamic loading; a response of components and structures to harsh environment. The materials discussed at D2FAM 2013

Symposium on engineering with nuclear explosives. Proceedings. Volume 2

International Nuclear Information System (INIS)

1970-05-01

This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. This proceedings is the record of the symposium

Symposium on engineering with nuclear explosives. Proceedings. Vol. 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1970-05-01

This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. These proceedings are the record of the symposium.

Symposium on engineering with nuclear explosives. Proceedings. Volume 2

Energy Technology Data Exchange (ETDEWEB)

NONE

1970-05-15

This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. This proceedings is the record of the symposium.

Symposium on engineering with nuclear explosives. Proceedings. Vol. 1

International Nuclear Information System (INIS)

1970-05-01

This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. These proceedings are the record of the symposium

10th International Symposium on Superconductivity

CERN Document Server

Hirabayashi, Izumi

1998-01-01

The International Symposium on Superconductivity, which has been held annu­ ally since 1988, is a forum for presenting the most up-to-date information about a broad range of research and development in superconductivity, from funda­ mental aspects to applications. More than 10 years have passed since the discovery of oxide superconductors and since various developments of applications began. It may be said that the prospects for application of oxide superconductors recently have opened up. Great progress has been made toward practical use, for example, of the flywheel, which uses bulk materials, and the high-performance cryo-cooled magnet made of bismuth wire. These were the results of persistent efforts to develop materials from the viewpoint of materials science and engineering. Also important is the progress in comprehensive understanding of high­ temperature superconductivity. Unique electronic properties of cuprates such as the non-Fermi liquid normal state, spin-charge separation, spin gap, and d-wav...

Book Symposium: Duncan Pritchard, Epistemic Angst (Princeton University Press, 2015, xiii + 236 pages

Directory of Open Access Journals (Sweden)

Duncan Pritchard

Full Text Available ABSTRACT This book symposium features three critical pieces dealing with Duncan Pritchard's book, 'Epistemic Angst'; the symposium also contains Pritchard's replies to his critics.

Symposium 1 of JENAM 2010

CERN Document Server

Molaro, Paolo; From Varying Couplings to Fundamental Physics

2011-01-01

Nature is characterized by a number of physical laws and fundamental dimensionless couplings. These determine the  properties of our physical universe, from the size of atoms, cells and mountains to the ultimate fate of the universe as a whole. Yet it is rather remarkable how little we know about them. The constancy of physical laws is one of the cornerstones of the scientific research method, but for fundamental couplings this is an assumption with no other justification  than a historical assumption. There is no 'theory of constants' describing their role in the underlying theories and how they relate to one another or how many  of them are truly fundamental.  Studying the behaviour of these quantities throughout the history of the universe is an effective way to probe fundamental physics. This explains why the ESA and ESO include varying fundamental constants among their key science drivers for the next generation of facilities. This symposium discussed the state-of-the-art in the field, as well as the...

Proceedings of KURRI symposium on criticality safety

International Nuclear Information System (INIS)

Nishina, Kojiro; Kanda, Keiji

1984-01-01

On August 8, 1984, at the Reactor Application Center of the Research Reactor Institute, Kyoto University, the symposium on criticality safety was held, and 81 participants from various fields of reactor physics, nuclear fuel cycle engineering, reactor chemistry, nuclear chemistry, health physics and so on discussed the problem. The gists of the presentation are collected in this report. The contents are the techniques of evaluating criticality safety in respective fuel facilities, the system of control and its concept, the course and plan of the research on criticality safety in Japan and foreign countries, the techniques of determining multiplication factor and so on, and the review of present status, the pointing-out of problems and the report of new techniques were made. The measures coping with criticality safety have been mostly to meet urgent demand, but its fundamental examination and long term research should be carried out. This symposium was planned as the preparation for such research project, and favorable comment was given by the participants. In the next symposium, it is considered better to limit the themes and to allot more time to respective lectures. (Kako, I.)

Proceedings of the international symposium: Transfer of radionuclides in biosphere. Prediction and assessment

International Nuclear Information System (INIS)

Amano, Hikaru

2003-09-01

The International Symposium : Transfer of Radionuclides in Biosphere - Prediction and Assessment was held at Mito on the 18th and 19th of December 2002. This International Symposium was organized by the Interchange Committee on Radionuclide Transfer in Soil Ecosphere. This project is the 3rd Phase Crossover Research, which is engaged in cooperation with five organizations: Japan Atomic Energy Research Institute (JAERI), Meteorological Research Institute (MRI), National Institute of Radiological Sciences (NIRS), RIKEN (Institute of Physical and Chemical Research) and Institute for Environmental Sciences (IES). The main objective of this symposium is to discuss and exchange recent findings and ideas in the area of the behavior and transfer of radionuclides in biosphere. One of the important topics in this symposium is to discuss a suitable transfer model and transfer parameters which may be adapted for Southeast Asian countries including Japan, as environmental conditions and foodstuffs in this region are significantly different from those in Europe and North America. It will be hoped that the predictions of the consequences of the release of radionuclides in the terrestrial environment will be improved through exchange of views and new results. The symposium consisted of 12 invited lectures and 44 poster presentations. The 117 participants attended the symposium, including 19 foreigners coming from 12 countries. (author)

The fifth international symposium ''atomic cluster collisions''. ISACC 2011. Book of Abstracts

International Nuclear Information System (INIS)

2011-01-01

promote, as all former ones, the growth and exchange of scientific information on the structure, properties and dynamics of complex nuclear, atomic, molecular, cluster, nanoscopic and biological systems studied primarily by means of photonic, electronic and heavy particle collisions. In the symposium, particular attention will be devoted to new developments such as the employment of Free Electron Lasers FEL's for the study of dynamical, in particular time dependent phenomena, many-body effects taking place in clusters, nanostructures, molecular and biological systems, which include problems of fusion and fission, fragmentation, collective electron excitations, phase transitions, radiation damage and many more. Nonlinear phenomena in the photoionization of clusters are explored by the new excitation possibilities in the VUV and soft X-ray regime for the first time. Both experimental and theoretical aspects of cluster physics uniquely placed between nuclear physics on the one hand and atomic, molecular, and solid state physics on the other will be subjects of this symposium.

CONFERENCE REVIEW:V. International Educational Technology Symposium

Directory of Open Access Journals (Sweden)

Reviewed by Mubin KIYICI

2005-10-01

Full Text Available 167V. International Educational Technology SymposiumWas held in Sakarya UniversityBetween 21 – 23 September 2005Reviewed by Mubin KIYICISakarya Universitymkiyici@anadolu.edu.trV. International Educational Technology Symposium was held in Sakarya University heldbetween 21 – 23 September 2005 by cooperation with Eastern Mediterranean University,Louisiana State University, Governors State University and Ohio University, and TOJET(The Turkish Online Journal of Educational Technology journal, at Sakarya UniversityCampus. Assoc. Prof. Dr. Aytekin ISMAN who was conference coordinator and Editor inchief of TOJET spoke at the opening ceremony of symposium. His speech was related todiffusion of distance education and diffusion of usage educational technology. And thenProf. Dr. Mehmet DURMAN who is Rector of Sakarya University, talked about aapplications of Distance Education which is applied by Sakarya University and educationaltechnology applications in Tukey. His Speech is here:168Dear GuestsWelcome to the “5th International Educational Technology ConferenceIETC/EGİTEK 2005. It is an international educational activity for academics,teachers and educators. This conference is now a well known educationaltechnology event and the number of paper submissions and attendeesincrease every year.This year, IETC-2005 received 268 applications. The conference academicadvisory board accepted 209 applications.IETC-2005 promotes the development and dissemination of theoreticalknowledge, conceptual research, and professional knowledge throughconference activities, the conference proceeding book, and the TurkishOnline Journal of Educational Technology (TOJET. Its focus is to create anddisseminate knowledge about the use instructional technology for learningand teaching in education.The main theme of IETC-2005 is distance education. Distance education is adelivery system of teaching and learning, when the teacher and the studentare separated by physical distance

Physiological levels of blood coagulation factors IX and X control coagulation kinetics in an in vitro model of circulating tissue factor

International Nuclear Information System (INIS)

Tormoen, Garth W; Khader, Ayesha; Gruber, András; McCarty, Owen J T

2013-01-01

Thrombosis significantly contributes to cancer morbidity and mortality. The mechanism behind thrombosis in cancer may be circulating tissue factor (TF), as levels of circulating TF are associated with thrombosis. However, circulating TF antigen level alone has failed to predict thrombosis in patients with cancer. We hypothesize that coagulation factor levels regulate the kinetics of circulating TF-induced thrombosis. Coagulation kinetics were measured as a function of individual coagulation factor levels and TF particle concentration. Clotting times increased when pooled plasma was mixed at or above a ratio of 4:6 with PBS. Clotting times increased when pooled plasma was mixed at or above a ratio of 8:2 with factor VII-depleted plasma, 7:3 with factor IX- or factor X-depleted plasmas, or 2:8 with factor II-, V- or VIII-depleted plasmas. Addition of coagulation factors VII, X, IX, V and II to depleted plasmas shortened clotting and enzyme initiation times, and increased enzyme generation rates in a concentration-dependent manner. Only additions of factors IX and X from low-normal to high-normal levels shortened clotting times and increased enzyme generation rates. Our results demonstrate that coagulation kinetics for TF particles are controlled by factor IX and X levels within the normal physiological range. We hypothesize that individual patient factor IX and X levels may be prognostic for susceptibility to circulating TF-induced thrombosis. (paper)

WE-NET Hydrogen Energy Symposium proceedings; WE-NET suiso energy symposium koen yokoshu

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-02-24

The research and development of WE-NET (World Energy Network) was started in 1993 as a NEDO (New Energy and Industrial Technology Development Organization) project in the New Sunshine Program of Agency of Industrial Science and Technology, Ministry of International Trade and Industry, and aims to contribute to the improvement of global environment and to ease the difficult energy supply/demand situation. The ultimate goal of WE-NET is the construction of a global-scale clean energy network in which hydrogen will be produced from renewable energies such as water and sunshine for distribution to energy consuming locations. Experts are invited to the Symposium from the United States, Germany, and Canada. Information is collected from the participants on hydrogen energy technology development in the three countries, the result of the Phase I program of WE-NET is presented to hydrogen energy scientists in Japan, and views and opinions on the project are collected from them. Accommodated in the above-named publication are 30 essays and three special lectures delivered at the Symposium. (NEDO)

1993 Proceedings volume 1--Contamination control; symposium on minienvironments; symposium on biocontamination control

International Nuclear Information System (INIS)

Anon.

1993-01-01

Volume 1 contains the proceedings from three symposia. Contamination Control includes the following topics: Atmospheric pressure ionization mass spectroscopy (APIMS) applications; APIMS development; contamination control in cleanroom air; defect reduction in semiconductor processes; contamination control in the aerospace industry; filtration of gases; ultrapure chemical and DI water; filtration of chemicals; wafer cleaning/trace contaminant effects; wafer cleaning techniques; detection of particles in UHP fluids; detection of surface particles; modeling contamination; detection of surface organics; modeling, particle transport, deposition, and removal; and detection of surface metallics. Symposium on Minienvironments includes the following: design of minienvironments; robotics and I/O transport; testing, methods, and standards. The Symposium on Biocontamination Control includes the following: microbial CC facility requirements in pharmaceutical, biological, and medical device manufacture; cleaning and disinfecting methods and devices for bio CC; biocontamination control devices, methodology, and standards, airborne and surface microbial monitoring methods and devices; and regulatory issues in bio CC--present and future. All papers within the scope of the Energy Data Base have been processed separately for inclusion on the data base

Coal dust symposium

Energy Technology Data Exchange (ETDEWEB)

1981-03-01

This paper gives a report of the paper presented at the symposium held in Hanover on 9 and 10 February 1981. The topics include: the behaviour of dust and coal dust on combustion and explosion; a report on the accidents which occurred at the Laegerdorf cement works' coal crushing and drying plant; current safety requirements at coal crushing and drying plant; and coal crushing and drying. Four papers are individually abstracted. (In German)

The Future of Electronic Power Processing and Conversion: Highlights from FEPPCON IX

DEFF Research Database (Denmark)

Enslin, Johan H.; Blaabjerg, Frede; Tan, Don F.D.

2017-01-01

Since 1991, every second year the IEEE Power Electronics Society (PELS) has organized the technical long-range planning meeting "Future of Electronic Power Processing and Conversion" (FEPPCON). FEPPCON IX was held 12-16 June 2017 in beautiful Kruger Park in South Africa (Figure 1). The overall go...

Proceedings of the 9th symposium on advanced photon research

International Nuclear Information System (INIS)

2010-03-01

The 9th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on July 31- August 1, 2008. This report consists of invited and contributed papers presented at the oral and poster sessions in The Symposium. The 25 of the presented papers are indexed individually. (J.P.N.)

Proceedings of the 21. European Cosmic Ray Symposium

International Nuclear Information System (INIS)

Kiraly, P.; Kudela, K.; Wolfendale, A. W.

2008-09-01

Scientific symposium deals with problems of cosmic ray. The Symposium included the following sessions: (1): Relationship of cosmic rays to the environment; (2) Energetic particles and the magnetosphere of the Earth; (3) Energetic particles in the heliosphere; (4) Solar-terrestrial effects on different time scales; (5) Cosmic rays below the knee; (6) Cosmic rays above the knee (7) High energy interactions; (8) GeV and TeV gamma ray astronomy; (9) European projects related to cosmic rays; Future perspectives. Proceedings contains 122 papers dealing with the scope of INIS.

Proceedings of a symposium about PEARL in Augsburg

International Nuclear Information System (INIS)

1977-05-01

Both, the PDV Project Management of the Gesellschaft fuer Kerforschung mbH, Karlsruhe, and the VDI/VDE-Gesellschaft Mess- und Regelungstechnik, were organizing on March 9, 1977, a public symposium about PEARL, the unified realtime programming language in the Federal Republic of Germany. This report contains papers of speeches given at the symposium about the following topics: 1) The sponsoring of PEARL within the Project PDV (history, status, future, standardization); 2) PEARL as compared with other realtime languages; 3) experience with present PEARL subsets (both in laboratory and industrial environment). (orig.) [de

I Symposium of Elite Performance in Combat Sports

Directory of Open Access Journals (Sweden)

Montse C. Ruiz

2017-07-01

Full Text Available This report presents a summary of the I Symposium of Elite Performance in Combat Sports held in Madrid, May 27, 2017. The symposium, organized by the Faculty of Sport Sciences-INEF of the Polytechnic University of Madrid, aimed to bring science closer to practice. A panel of highly successful athletes involved in karate, fencing, and taekwondo shared their experiences. The speakers presented crucial topics for an optimal preparation and high level performance such as strength training, sport psychology, brain maturation, sports nutrition, competition planning, sport injuries, and perceptual-decision making training.

ASHRAE transactions 1999: Technical and symposium papers. Volume 105, Part 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-07-01

This book contains 50 technical papers and 83 symposium papers. The symposium papers are divided into the following sections: Computer Models for Fire and Smoke Control; Thermal Properties and Estimation Techniques of Ground-Coupled Heat Pump Boreholes, Grouts, and Fills; Advances in Thermal and Fluid Characteristics in HVAC and Refrigeration Processes; Effects of Controlling Humidity on Energy Consumption of Supermarkets; Fault Detection and Diagnostics -- Learning from Building Operations; Innovative Methods for Room Air Distribution; Laboratory Exhaust Fans and Stacks; Full Scale Tests in Very Large Spaces and CFD Modeling; Laboratory Verification and Testing; Absorption/Sorption Heat Pumps and Refrigeration Systems; Attic and Cathedral Ceilings II; Health Care Issues Update; Computers in HVAC Education; Multizone Modeling of Ventilation and Infiltration in Residential Buildings; Documenting the Value of a Facility of Corporate Energy Manager; Water Heating systems Information and Design Tools; Snow Melting: System Assessment; Fault Detection and Diagnostics (FDD) Methods and Evaluation Techniques; The Effects of Commissioning and O and M on IAQ; Energy Efficiency in Commercial Food Service Facilities; Historical Views of Steam, Ice and Refrigerants; Low Total Equivalent Warming Impact (TWEI) Unitary Air Conditioners and Heat Pump Systems; and Second Law Studies of Systems and Processes. Separate abstracts were prepared for most papers in this book.

The paediatric cardiac centre for Africa--proceedings of the March 2012 symposium.

Science.gov (United States)

Kinsley, Robin H; Edwin, Frank; Entsua-Mensah, Kow

2013-04-01

The Pediatric Cardiac Centre for Africa (PCCA) was opened by national patron Mr Nelson Mandela on November 7, 2003. In 2008, the Centre's international pediatric cardiac symposium was introduced as a learning forum for pediatric cardiac surgeons and cardiologists in the continent. The symposium has consistently grown in attendance and attracted distinguished leaders in the field. The 2012 symposium featured Dr. Thomas Spray of Children's Hospital of Philadelphia, Dr. David Barron of Birmingham Children's Hospital, and Dr. John Brown of Indiana University School of Medicine as guest speakers. Experience of the Fontan procedure, the small aortic root, hypoplastic left heart syndrome, right ventricular outflow tract reconstruction, transposition of the great arteries, and interrupted aortic arch were the highlights of the symposium. In the "African Corner," centers in South Africa, Ghana, and Angola presented work done from across the African continent.

PHKA2 mutation spectrum in Korean patients with glycogen storage disease type IX: prevalence of deletion mutations.

Science.gov (United States)

Choi, Rihwa; Park, Hyung-Doo; Kang, Ben; Choi, So Yoon; Ki, Chang-Seok; Lee, Soo-Youn; Kim, Jong-Won; Song, Junghan; Choe, Yon Ho

2016-04-21

Molecular diagnosis of glycogen storage diseases (GSDs) is important to enable accurate diagnoses and make appropriate therapeutic plans. The aim of this study was to evaluate the PHKA2 mutation spectrum in Korean patients with GSD type IX. Thirteen Korean patients were tested for PHKA2 mutations using direct sequencing and a multiplex polymerase chain reaction method. A comprehensive review of the literature on previously reported PHKA2 mutations in other ethnic populations was conducted for comparison. Among 13 patients tested, six unrelated male patients with GSD IX aged 2 to 6 years at the first diagnostic work-up for hepatomegaly with elevated aspartate transaminase (AST) and alanine transaminase (ALT) were found to have PHKA2 mutations. These patients had different PHKA2 mutations: five were known mutations (c.537 + 5G > A, c.884G > A [p.Arg295His], c.3210_3212delGAG [p.Arg1072del], exon 8 deletion, and exons 27-33 deletion) and one was a novel mutation (exons 18-33 deletion). Notably, the most common type of mutation was gross deletion, in contrast to other ethnic populations in which the most common mutation type was sequence variant. This study expands our knowledge of the PHKA2 mutation spectrum of GSD IX. Considering the PHKA2 mutation spectrum in Korean patients with GSD IX, molecular diagnostic methods for deletions should be conducted in conjunction with direct sequence analysis to enable accurate molecular diagnosis of this disease in the Korean population.

Structure and properties of interfaces in ceramics

International Nuclear Information System (INIS)

Bonnell, D.; Ruehle, M.; Chowdhry, U.

1995-01-01

The motivation for the symposium was the observation that interfaces in crystallographically and compositionally complex systems often dictate the performance and reliability of devices that utilize functional ceramics. The current level of understanding of interface-property relations in silicon-based devices required over 30 years of intensive research. Similar issues influence the relationship between atomic bonding at interfaces and properties in functional ceramic systems. The current understanding of these complex interfaces does not allow correlation between atomic structure and interface properties, in spite of their importance to a number of emerging technologies (wireless communications, radar-based positioning systems, sensors, etc.). The objective of this symposium was to focus attention on these fundamental issues by featuring recent theoretical and experimental work from various disciplines that impact the understanding of interface chemistry, structure, and properties. The emphasis was on relating properties of surfaces and interfaces to structure through an understanding of atomic level phenomena. Interfaces of interest include metal/ceramic, ceramic/ceramic, ceramic/vapor, etc., in electronic, magnetic, optical, ferroelectric, piezoelectric, and dielectric applications. Sixty one papers have been processed separately for inclusion on the data base

Proceedings of the first symposium on science of hadrons under extreme conditions

Energy Technology Data Exchange (ETDEWEB)

Chiba, Satoshi; Maruyama, Toshiki [eds.

1999-08-01

The first symposium on Science of Hadrons under Extreme Conditions, organized by the Research Group for Hadron Science, Advanced Science Research Center, was held at Tokai Research Establishment of JAERI on March 11 and 12, 1999. The symposium was devoted for discussions and presentations of research results in wide variety of fields such as observation of X-ray pulsars, theoretical studies of nuclear matter, nuclear structure, low- and high-energy nuclear reactions and QCD. Thirty seven papers on these topics presented at the symposium are indexed individually. (J.P.N.)

'HTA for Crisis': sharing experiences during the 7th EBHC Symposium.

Science.gov (United States)

Wladysiuk, Magdalena; Tabor, Anna; Godman, Brian

2013-02-01

The Central and Eastern European Society of Technology Assessment in Health Care was founded in Krakow, Poland in 2003. On October 8th and 9th, the 7th symposium took place titled 'HTA for Crisis'. This meeting was attended by over 250 decision makers, evidence-based specialists, healthcare managers, commercial company personnel and experts. The symposium was principally divided into four main themes: insurance in times of crisis; importance of pricing of health services in times of crisis; managing welfare benefits in times of crisis and Health Technology Assessment in crisis-laden countries. The symposium finished by debating potential ways forward for healthcare systems in times of crisis.

Results of a phase I/II open-label, safety and efficacy trial of coagulation factor IX (recombinant), albumin fusion protein in haemophilia B patients.

Science.gov (United States)

Martinowitz, U; Lissitchkov, T; Lubetsky, A; Jotov, G; Barazani-Brutman, T; Voigt, C; Jacobs, I; Wuerfel, T; Santagostino, E

2015-11-01

rIX-FP is a coagulation factor IX (recombinant), albumin fusion protein with more than fivefold half-life prolongation over other standard factor IX (FIX) products available on the market. This prospective phase II, open-label study evaluated the safety and efficacy of rIX-FP for the prevention of bleeding episodes during weekly prophylaxis and assessed the haemostatic efficacy for on-demand treatment of bleeding episodes in previously treated patients with haemophilia B. The study consisted of a 10-14 day evaluation of rIX-FP pharmacokinetics (PK), and an 11 month safety and efficacy evaluation period with subjects receiving weekly prophylaxis treatment. Safety was evaluated by the occurrence of related adverse events, and immunogenic events, including development of inhibitors. Efficacy was evaluated by annualized spontaneous bleeding rate (AsBR), and the number of injections to achieve haemostasis. Seventeen subjects participated in the study, 13 received weekly prophylaxis and 4 received episodic treatment only. No inhibitors were detected in any subject. The mean and median AsBR were 1.25, and 1.13 respectively in the weekly prophylaxis arm. All bleeding episodes were treated with 1 or 2 injections of rIX-FP. Three prophylaxis subjects who were treated on demand prior to study entry had >85% reduction in AsBR compared to the bleeding rate prior to study entry. This study demonstrated the efficacy for weekly routine prophylaxis of rIX-FP to prevent spontaneous bleeding episodes and for the treatment of bleeding episodes. In addition no safety issues were detected during the study and an improved PK profile was demonstrated. © 2015 CSL Behring. Haemophilia published by John Wiley & Sons Ltd.

Symposium "Balans in Duurzaamheid"; 4 juni 2002 Rolzaal, Binnenhof, Den Haag

NARCIS (Netherlands)

Duijvenbooden W van; Poolman AM; MNP/Sector 5

2002-01-01

The symposium on 'Balance in Sustainability' was organised by the Office for Environmental Assessment (MNP) of the RIVM in The Hague on June 4th 2002. Mr Van Egmond, Director of the MNP started off the symposium with a presentation on the structure and the content of a 'Balance in Sustainability'.

5-ALA/PpIX fluorescence detection of gastrointestinal neoplasia

Science.gov (United States)

Borisova, Ekaterina G.; Vladimirov, Borislav; Terziev, Ivan; Ivanova, Radina; Avramov, Latchezar

2009-07-01

In the recent study delta-ALA/PpIX is used as fluorescent marker for dysplasia and tumor detection in esophagus, stomach and colon. ALA is administered per os six to eight (depending on the lesion location) hours before measurements at dose 20mg/kg weight. High-power light-emitting diode at 405 nm is used as an excitation source. Special opto-mechanical device is built for the LED to use the light guide of standard video-endoscopic system. Through endoscopic instrumental channel a fiber is applied to return information about fluorescence to microspectrometer. The fluorescence detected from tumor sites has very complex spectral origins. It consists of autofluorescence, fluorescence from exogenous fluorophores and re-absorption from the chromophores accumulated in the tissue investigated. Spectral features observed during endoscopic investigations could be distinct as the next regions: 450-630 nm region, where tissue autofluorescence is observed; 630-710 nm region, where fluorescence of PpIX is clearly pronounced; 530-580 nm region, where minima in the autofluorescence signal are observed, related to re-absorption of oxy-hemoglobin in this spectral area. Endogenous and exogenous fluorescence spectra are used to develop simple but effective algorithm, based on dimensionless ratio of the signals at 560 and 635 nm, for differentiation of normal/abnormal gastrointestinal tissues. Very good correlation between fluorescence signals and histology examination of the lesions investigated is achieved.

EDITORIAL: Nobel Symposium 148: Graphene and Quantum Matter Nobel Symposium 148: Graphene and Quantum Matter

Science.gov (United States)

Niemi, Antti; Wilczek, Frank; Ardonne, Eddy; Hansson, Hans

2012-01-01

The 2010 Nobel Symposium on Graphene and Quantum Matter, was held at the Grand Hotel in Saltsjöbaden south of Stockholm on 27-31 May. The main theme of the meeting was graphene, and the symposium turned out to be very timely: two of the participants, Andre Geim and Kanstantin Novoselov returned to Stockholm less then six months later to receive the 2010 Nobel Prize in Physics. In these proceedings leading experts give up-to-date, historical, experimental, theoretical and technological perspectives on the remarkable material graphene, and several papers also make connections to other states of quantum matter. Saltsjöbaden is beautifully situated in the inner archipelago of Stockholm. It provided a pleasant setting for the talks and the ensuing discussions that took place in an enthusiastic and friendly atmosphere. The social programme included a boat trip in the light summer night and a dinner at the renowned Grand Hotel. These proceedings are ordered thematically, starting with historical overviews, followed by first experimental and then theoretical papers on the physics of graphene. Next are several papers addressing more general topics in quantum matter and finally contributions on the technological applications of graphene. We hope that this volume will serve as a source of knowledge and inspiration for any physicist interested in graphene, and at the same time provide a snapshot of a young field of research that is developing at very high speed. We are grateful to Marja Fahlander for excellent administrative support, and to the Nobel Foundation who funded the symposium.

7th international symposium on internal combustion diagnostics. Proceedings; 7. Internationales Symposium fuer Verbrennungsdiagnostik. Beitraege

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

At one time combustion pressure indicating was the ''trigger'' for this symposium, and today it still serves as the basis for continued investigation of combustion phenomena. It now finds application throughout the development process, as more sophisticated analysis of conventional signals is possible. Understanding of localized combustion phenomena is substantially simplified by means of optical diagnostic methods, the application of which has reached a certain level of standardization. The presentations will cover specific topics including fuel spray analysis, ignition events and information about gas mixtures. The comparison and combination of results from measurement and simulation shed light on the complex processes in the combustion chamber. What's more, the linkage of two complementary methods offers substantial cost savings through reductions in test hardware and shorter development times. Focused application of all of the available tools allows us better to understand combustion processes, recognize the influential parameters and derive control algorithms. The latter are subsequently to be found in engines that fulfill both regulatory requirements and customer expectations. So it is that the symposium captures the current state of the art in combustion diagnostics through a combination of indicating, optical diagnostics and simulation, and offers both the methodology expert and the engine developer the ideal platform for discussion of today's issues - and to form their own opinions on them. Anyone wanting to keep up to date in this continuously developing and ever more complex area of activity certainly can't afford to miss our symposium. (orig.)

PREFACE: XXXIV Symposium on Nuclear Physics

Science.gov (United States)

Barrón-Palos, Libertad; Bijker, Roelof

2011-10-01

In the present volume of the Journal of Physics: Conference Series we publish the proceedings of the 'XXXIV Symposium on Nuclear Physics', which was held from 4-7 January 2011 at the Hacienda Cocoyoc, Morelos, Mexico. The proceedings consist of 19 contributions that were presented as invited talks at the meeting. The abstracts of all contributions, plenary talks and posters were published in the Conference Handbook. The Symposium on Nuclear Physics has a long and distinguished history. From the beginning it was intended to be a relatively small meeting designed to bring together some of the leading nuclear scientists in the field. Its most distinctive feature is to provide a forum for specialists in different areas of nuclear physics, both theorists and experimentalists, students, postdocs and senior scientists, in a relaxed and informal environment providing them with a unique opportunity to exchange ideas. From the first meeting in Oaxtepec in 1978, the Symposium has been organized every year without interruption, which makes the present Symposium the 34th in a row. The scientific program consisted of 27 invited talks and 17 posters on a wide variety of hot topics in contemporary nuclear physics, ranging from the traditional fields of nuclear structure (Draayer, Pittel, Van Isacker, Fraser, Lerma, Cejnar, Hirsch, Stránský and Rath) and nuclear reactions (Aguilera, Gómez-Camacho, Scheid, Navrátil and Yennello) to radioactive beams (Padilla-Rodal and Galindo-Uribarri), nuclear astrophysics (Aprahamian, Civitarese and Escher), hadronic physics (Bijker, Valcarce and Hess), fundamental symmetries (Liu, Barrón-Palos and Baessler) and LHC physics (Menchaca-Rocha and Paic). The high quality of the talks, the prestige of the speakers and the broad spectrum of subjects covered in the meeting, shows that nuclear physics is a very active area at the frontier of scientific research which establishes bridges between many different disciplines. Libertad Barr

Quark matter coupled to domain walls in Bianchi types II, VIII and IX ...

Indian Academy of Sciences (India)

In this study of Bianchi types II, VIII and IX Universes, quark matter coupled to domain walls in the ... The self-bound state appears to be at ρ ... The observations suggest that the Hubble expansion of the Universe ... Taking motivation from.

Diversity in the Workplace. Symposium.

Science.gov (United States)

2002

Three papers comprise this symposium on diversity in the workplace. "Factors That Assist and Barriers That Hinder the Success of Diversity Initiatives in Multinational Corporations" (Rose Mary Wentling) reports that factors that assisted in the success were classified under diversity department, human, and work environment; barriers were…

Annual Symposium in Electronics Packaging

CERN Document Server

1991-01-01

Each May, the Continuing Education Division of the T.J.Watson School of Engineering, Applied Science and Technology at the State University of New York at Binghamton sponsors an Annual Symposium in Electronics Packaging in cooperation with local professional societies (IEEE, ASME, SME, IEPS) and UnlPEG (the University-Industry Partnership for Economic Growth.) Each volume of this Electronics Packaging Forum series is based on the the preceding Symposium, with Volume Two based on the 1990 presentations. The Preface to Volume One included a brief definition of the broad scope of the electronics packaging field with some comments on why it has recently assumed such a more prominent priority for research and development. Those remarks will not be repeated here; at this point it is assumed that the reader is a professional in the packaging field, or possibly a student of one of the many academic disciplines which contribute to it. It is worthwhile repeating the series objectives, however, so the reader will be cle...

2015 International Symposium in Statistics

CERN Document Server

2016-01-01

This proceedings volume contains eight selected papers that were presented in the International Symposium in Statistics (ISS) 2015 On Advances in Parametric and Semi-parametric Analysis of Multivariate, Time Series, Spatial-temporal, and Familial-longitudinal Data, held in St. John’s, Canada from July 6 to 8, 2015. The main objective of the ISS-2015 was the discussion on advances and challenges in parametric and semi-parametric analysis for correlated data in both continuous and discrete setups. Thus, as a reflection of the theme of the symposium, the eight papers of this proceedings volume are presented in four parts. Part I is comprised of papers examining Elliptical t Distribution Theory. In Part II, the papers cover spatial and temporal data analysis. Part III is focused on longitudinal multinomial models in parametric and semi-parametric setups. Finally Part IV concludes with a paper on the inferences for longitudinal data subject to a challenge of important covariates selection from a set of large num...

High-resolution Laboratory Measurements of Coronal Lines near the Fe IX Line at 171 Å

Science.gov (United States)

Beiersdorfer, Peter; Träbert, Elmar

2018-02-01

We present high-resolution laboratory measurements in the spectral region between 165 and 175 Å that focus on the emission from various ions of C, O, F, Ne, S, Ar, Fe, and Ni. This wavelength region is centered on the λ171 Fe IX channel of the Atmospheric Imaging Assembly on the Solar Dynamics Observatory, and we place special emphasis on the weaker emission lines of Fe IX predicted in this region. In general, our measurements show a multitude of weak lines missing in the current databases, where the emission lines of Ni are probably most in need of further identification and reclassification. We also find that the wavelengths of some of the known lines need updating. Using the multi-reference Møller–Plesset method for wavelength predictions and collisional-radiative modeling of the line intensities, we have made tentative assignments of more than a dozen lines to the spectrum of Fe IX, some of which have formerly been identified as Fe VII, Fe XIV, or Fe XVI lines. Several Fe features remain unassigned, although they appear to be either Fe VII or Fe X lines. Further work will be needed to complete and correct the spectral line lists in this wavelength region.

The multi-facets of sustainable nanotechnology – Lessons from a nanosafety symposium

Science.gov (United States)

George, Saji; Ho, Shirley S.; Wong, Esther S. P.; Tan, Timothy Thatt Yang; Verma, Navin Kumar; Aitken, Robert J.; Riediker, Michael; Cummings, Christopher; Yu, Liya; Wang, Zheng Ming; Zink, Daniele; Ng, Zhihan; Loo, Say Chye Joachim; Ng, Kee Woei

2015-01-01

Abstract An international symposium for nanosafety was held recently at the Nanyang Technological University in Singapore. Topics relating to understanding nanomaterial properties, tools, and infrastructure required for predicting hazardous outcomes, measuring nanomaterial exposure levels, systems approach for risk assessment and public’s perception of nanotechnology were covered. The need for a multidisciplinary approach, across both natural and social sciences, for developing sustainable nanotechnology solutions was heavily emphasized. This commentary highlights the major issues discussed and the commitment of the nanosafety research community in Singapore to contribute collectively to realise the vision of sustainable nanotechnology. PMID:25976321

Summary of Numerical Modeling for Underground Nuclear Test Monitoring Symposium

International Nuclear Information System (INIS)

Taylor, S.R.; Kamm, J.R.

1993-01-01

This document contains the Proceedings of the Numerical Modeling for Underground Nuclear Test Monitoring Symposium held in Durango, Colorado on March 23-25, 1993. The symposium was sponsored by the Office of Arms Control and Nonproliferation of the United States Department of Energy and hosted by the Source Region Program of Los Alamos National Laboratory. The purpose of the meeting was to discuss state-of-the-art advances in numerical simulations of nuclear explosion phenomenology for the purpose of test ban monitoring. Another goal of the symposium was to promote discussion between seismologists and explosion source-code calculators. Presentation topics include the following: numerical model fits to data, measurement and characterization of material response models, applications of modeling to monitoring problems, explosion source phenomenology, numerical simulations and seismic sources

Proceedings of the 3rd international symposium on material chemistry in nuclear environment (MATERIAL CHEMISTRY '02)

International Nuclear Information System (INIS)

2003-03-01

The volume contains all presented papers during the 3rd International Symposium on Material Chemistry in Nuclear Environment: MATERIAL CHEMISTRY 02 (MC'02), held March 13-15, 2002. The purpose of this symposium is to provide an international forum for the discussion of recent progress in the field of materials chemistry in nuclear environments. This symposium intends to build on the success of the previous symposiums held in Tsukuba in 1992 and 1996. The topics discussed in the symposium MC'02 are Chemical Reaction and Thermodynamics, Degradation Phenomena, New Characterization Technology, Fabrication and New Materials, Composite Materials, Surface Modification, and Computational Science. The 61 of the presented papers are indexed individually. (J.P.N.)

Overview of symposium on storage of spent fuel from power reactors

International Nuclear Information System (INIS)

Bonne, A.; Crijns, M.J.; Dyck, H.P.

2001-01-01

An International Symposium on Storage of Spent Fuel from Power Reactors was held in Vienna from 9-13 November 1998. The Symposium was organized by the International Atomic Energy Agency in co-operation with the OECD Nuclear Energy Agency. Of the one hundred sixty participants registered, one hundred twenty-five (including 3 observers) representing 35 countries and 4 international organizations, attended the Symposium. 20 participants from developing countries received Agency's grants. During 4 main Sessions, 44 oral presentations of papers were made and subsequent discussions held. At a poster session 13 papers were presented. This paper will give an overview of the Symposium. The Symposium gave an opportunity to exchange information on the state of art and prospects of spent fuel storage, to discuss the worldwide situation and the major factors influencing the national policies in this field and to identify the most important directions that national efforts and international co-operation in this area should take. It was obvious from the papers presented and the discussions that the handling and storage of spent fuel is continuously taking place safely. Dominant messages retrieved from the Symposium are that the primary spent fuel management solution for the next decades will be interim storage, the duration time of interim storage becomes longer than earlier anticipated and the storage facilities will have to be designed for receiving also spent fuel from advanced fuel cycle practices (i.e. high burnup and MOX spent fuel). It was noted that the handling and storage of spent fuel is a mature technology and meets the stringent safety requirements applicable in the different countries. The changes in nuclear policy and philosophy across the world, and practical considerations, have made interim storage a real necessity in the nuclear power industry. (author)

NuPEER Dijon 2005 Symposium. Ageing issues in nuclear power plants

Energy Technology Data Exchange (ETDEWEB)

Emond, David (ed.) [BCCN, Autorite de Surete Nucleaire, ASN, 6, place du Colonel Bourgoin, 75572 Paris Cedex 12 (France)

2005-07-01

The French Nuclear Safety Authority (ASN) organized an international symposium on regulatory aspects of ageing issues for nuclear pressure equipment. The ageing of nuclear pressure equipment is an issue of growing importance for nuclear regulators and material experts worldwide as age-related degradation of major pressure-retaining components challenges the remaining operating life of nuclear power plants. This symposium aimed at providing a forum for technical exchange among the staffs responsible for nuclear pressure equipment within the safety authorities and the associated expertise organisations. The contents of the symposium is as follows: 1. Control and supervision of safety of nuclear pressure equipment in France and abroad; 1.1. Position of the French Nuclear Safety Authority (1 paper); 1.2. Regulatory practices worldwide (4 papers); 1.3. Licence renewal: Field experience (2 papers); 1.4. Role of international organisations (1 paper); 2. Management of equipment and materials: From design to degradation mechanisms; 2.1. Operation and equipment (4 papers); 2. Evolution of materials (4 papers); 2.3. Fatigue degradation mechanisms (3 papers); 2.4. Contribution of research and development (4 papers); 3. In-service inspection: Evolutions, methods and strategies; 3.1. Methods and evolution (1 paper); 3.2. Qualification of methods (2 papers); 3.3. Surveillance strategies (2 papers); 4. Testimonies and points of view of utilities (3 papers); 5. Ageing issues taken into account in non nuclear fields (2 papers). The symposium began with workshops devoted to: Operation and equipment; Behaviour of materials; Fatigue degradations; Contributions of research and development. The symposium continued with plenary session that addressed the following issues: Control and supervision of safety of nuclear pressure equipment; Role of international organisations; In-service inspection: Objectives, methods and strategies; Point of view of utilities; Technical summary and

Kinetic data bank for Ramona of the Siemens 9x9-IX

International Nuclear Information System (INIS)

Alonso V, G.

1993-12-01

With the purpose of making the transitory analyses of the Laguna Verde Nuclear Power station when Siemens fuel of the type 9x9-IX is used, proposed for the cycle 2 of the Unit 2, the kinetic data bank in hot condition for the Ramona code has been generated. (Author)

The Bianchi IX model in loop quantum cosmology

International Nuclear Information System (INIS)

Bojowald, Martin; Date, Ghanashyam; Hossain, Golam Mortuza

2004-01-01

The Bianchi IX model has been used often to investigate the structure close to singularities of general relativity. Its classical chaos is expected to have, via the BKL scenario, implications even for the approach to general inhomogeneous singularities. Thus, it is a popular model to test consequences of modifications to general relativity suggested by quantum theories of gravity. This paper presents a detailed proof that modifications coming from loop quantum gravity lead to a non-chaotic effective behaviour. The way this is realized, independently of quantization ambiguities, suggests a new look at initial and final singularities

Measurement of rock properties at elevated pressures and temperatures

International Nuclear Information System (INIS)

Pincus, H.J.; Hoskins, E.R.

1985-01-01

The papers in this volume were presented at an ASTM symposium held on 20 June 1983 in conjunction with the 24th Annual Rock Mechanics Symposium at Texas A and M University, College Station, TX. The purpose of these papers is to present recent developments in the measurement of rock properties at elevated pressures and temperatures, and to examine and interpret the data produced by such measurement. The need for measuring rock properties at elevated pressures and temperatures has become increasingly important in recent years. Location and design of nuclear waste repositories, development of geothermal energy sites, and design and construction of deep excavations for civil, military, and mining engineering require significantly improved capabilities for measuring rock properties under conditions substantially different from those prevailing in most laboratory and in situ work. The development of high-pressure, high-temperature capabilities is also significant for the analysis of tectonic processes

2016 Gilbert W. Beebe symposium

Science.gov (United States)

The National Academies of Sciences, Engineering, and Medicine is hosting the 2016 Gilbert W. Beebe Symposium. Its focus will be on commemorating the 1986 Chernobyl nuclear reactor accident and discussing the achievements of 30 years of studies on the radiation health effects following the accident and future research directions.

Hemophilia B with mutations at glycine-48 of factor IX exhibited delayed activation by the factor VIIa-tissue factor complex.

Science.gov (United States)

Wu, P C; Hamaguchi, N; Yu, Y S; Shen, M C; Lin, S W

2000-10-01

Gly-48 is in the conserved DGDQC sequence (residues 47-51 of human factor IX) of the first EGF (EGF-1)-like domain of factor IX. The importance of the Gly-48 is manifested by two hemophilia B patients; factor IXTainan and factor IXMalmo27, with Gly-48 replaced by arginine (designated IXG48R) and valine (IXG48V), respectively. Both patients were CRM+ exhibiting mild hemophilic episodes with 25% (former) and 19% (latter) normal clotting activities. We characterize both factor IX variants to show the roles of Gly-48 and the conservation of the DGDQC sequence in factor IX. Purified plasma and recombinant factor IX variants exhibited approximately 26%-27% normal factor IX's clotting activities with G48R or G48V mutation. Both variants depicted normal quenching of the intrinsic fluorescence by increasing concentrations of calcium ions and Tb3+, indicating that arginine and valine substitution for Gly-48 did not perturb the calcium site in the EGF-1 domain. Activation of both mutants by factor XIa appeared normal. The reduced clotting activity of factors IXG48R and IXG48V was attributed to the failure of both mutants to cleavage factor X: in the presence of only phospholipids and calcium ions, both mutants showed a 4 to approximately 7-fold elevation in Km, and by adding factor VIIIa to the system, although factor VIIIa potentiated the activation of factor X by the mutants factor IXaG48R and factor IXaG48V, a 2 to approximately 3-fold decrease in the catalytic function was observed with the mutant factor IXa's, despite that they bound factor VIIIa on the phospholipid vesicles with only slightly reduced affinity when compared to wild-type factor IXa. The apparent Kd for factor VIIIa binding was 0.83 nM for normal factor IXa, 1.74 nM for IXaG48R and 1.4 nM for IXaG48V. Strikingly, when interaction with the factor VIIa-TF complex was examined, both mutations were barely activated by the VIIa-TF complex and they also showed abnormal interaction with VIIa-TF in bovine

Proceedings of the symposium on advanced measurement techniques and instrumentation: abstract book

International Nuclear Information System (INIS)

Kale, Y.B.; Kushwaha, M.; Somkuwar, S.P.; Ajayakumar, S.; Sampathkumar, R.

2011-01-01

In order to consolidate the existing knowledge base and further to focus on the future directions of the field of advanced measurement techniques and instrumentation, Bhabha Atomic Research Centre has organized a three-day symposium on 'Advanced Measurement Techniques and Instrumentation' at Multi Purpose Hall, Training School Hostel, Anushaktinagar, Mumbai during February 02-04, 2011. The symposium is aimed at providing a forum to discuss the emerging trends and challenges ahead in the important area of measurement science and technology. This is a unique symposium, which brings together scientists and engineers from all disciplines and provides them a platform for close interaction to exchange ideas, methodologies and expertise, which is extremely important for synergic growth of this field. The symposium consists of 27 talks, which include keynote address, plenary and invited talks, and 63 contributory papers. The abstracts of these papers are brought to you in this volume. Readers may observe that the scientific programme of the symposium covers a wide ranging issues including advanced scientific concepts in measurements, instrumentation strategies, mathematical techniques and development of devices for applications in fundamental physics, astrophysics, fusion plasmas, nuclear reactors, accelerators, environment, chemical and biological sciences, and national security. Papers relevant to INIS are indexed separately

Proceedings of the 2002 symposium on nuclear data

Energy Technology Data Exchange (ETDEWEB)

Ohsawa, Takaaki [Kinki Univ., Higashi-Osaka, Osaka (Japan); Fukahori, Tokio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

2003-06-01

The 2002 Symposium on Nuclear Data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 21st and 22nd of November 2002. Japanese Nuclear Data Committee and Nuclear Data Center, JAERI organized this symposium. In the oral sessions, presented were 18 papers on topics of release of JENDL-3.3, requests from users, status of FP nuclear data, international activities and other subjects. In the poster session, presented were 33 papers concerning experiments, evaluations, benchmark tests and on-line database on nuclear data. Those presented papers are compiled in the proceedings. (author)

Proceedings of national symposium on computer applications in power plants

International Nuclear Information System (INIS)

1992-01-01

The National Symposium on Computer Applications in Power Plants was organized to help promote exchange of views among scientists and engineers engaged in design, engineering, operation and maintenance of computer based systems in nuclear power plants, conventional power plants, heavy water plants, nuclear fuel cycle facilities and allied industries. About one hundred papers were presented at the Symposium. Those falling within the subject scope of INIS have been processed separately. (author)

Eighth International Symposium on Recent Advances in Environmental Health Research

Directory of Open Access Journals (Sweden)

Paul B. Tchounwou

2012-05-01

Full Text Available This special issue of International Journal of Environmental Research and Public Health is dedicated to the publication of selected papers presented at the Eighth International Symposium on Recent Advances in Environmental Health Research. The Symposium was organized by Jackson State University (JSU from September 18-21, 2011 at the Marriott Hotel in Jackson, Mississippi. It was built upon the overwhelming success of seven previous symposia hosted by JSU. [...

Estado de la investigacion en enfermería IX región de la Araucania, Temuco, Chile 2002 State of the research in nursing IX th region of the Araucania, Temuco, Chile 2002

Directory of Open Access Journals (Sweden)

Edith Elina Rivas Riveros

2005-09-01

Full Text Available El desarrollo de la investigación nos proyecta en la imagen de enfermera(o que queremos para el siglo XXI y el posicionamiento que tendremos. Esta imagen debe caracterizarse por intervenciones que demuestren calidad científica y humanización del cuidado. Las prácticas del cuidado, si bien son concebidas como una actividad práctica, necesitan de la actividad intelectual y de una masa crítica de investigadores e ideólogos que orienten las acciones, situación que debe fundamentarse en la evidencia. El propósito de esta investigación fue identificar, por medio de un estudio descriptivo, exploratorio y correlacional, el estado de la investigación en enfermería en la IX Región de la Araucania, Chile. Los objetivos específicos fueron analizar las condiciones en que se desarrolló el perfeccionamiento de las enfermeras en la IX Región y contribuir a la identificación de las líneas de investigación. El estudio recoge las características de los postgrados en enfermería en la IX Región, Chile: licenciatura, magíster y doctorado hasta el año 2002. Se concluye que en materia de enfoques predomina el positivista; las enfermeras están motivadas a perfeccionarse en programas de postgrado fundamen-talmente por razones de desarrollo personal y el deseo de contribuir a mejorar la profesión; quienes realizan estudios de postgrado se desempeñan en docencia en institutos y universidades, y la temática de las in-vestigaciones está básicamente orientada hacia la enseñanza de enfermería.The development of the investigation projected us in nurse’s image that we want for the XXI Century and the positioning that we will have. This image will be characterized by interventions that demonstrate scientific quality and humanization of the care. The practices of the care, although they are conceived as a practical activity, they need of the intellectual activity and of a critical mass of investigators and ideologists that guide the actions

Proceedings: 19th International Nondestructive Testing and Evaluation of Wood Symposium

Science.gov (United States)

Robert J. Ross; Raquel Gonçalves; Xiping Wang

2015-01-01

The 19th International Nondestructive Testing and Evaluation of Wood Symposium was hosted by the University of Campinas, College of Agricultural Engineering (FEAGRI/UNICAMP), and the Brazilian Association of Nondestructive Testing and Evaluation (ABENDI) in Rio de Janeiro, Brazil, on September 22–25, 2015. This Symposium was a forum for those involved in nondestructive...

Proceedings of 7th Symposium of the Croatian Radiation Protection Association

Energy Technology Data Exchange (ETDEWEB)

Barisic, D; Grahek, Z; Krajcar Bronic, I; Miljanic, S

2008-07-01

The 7th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; biological effects of radiation; radiation protection in medicine; radioecology and radon. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

Proceedings of 7th Symposium of the Croatian Radiation Protection Association

International Nuclear Information System (INIS)

Barisic, D.; Grahek, Z.; Krajcar Bronic, I.; Miljanic, S.

2008-01-01

The 7th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; biological effects of radiation; radiation protection in medicine; radioecology and radon. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide

NATO Symposium on Women and the World of Work

CERN Document Server

1982-01-01

From August 4 to 8, 1980, the Science Committee of the North Atlantic Treaty Organization (NATO) sponsored the symposium, "Women and the World of Work," which was held at the Hotel Sintra Estoril in the coastal area south of Lisbon, Portugal. This symposium hatl been "in progress" since 1977 when the idea to prepare a proposal for a NATO­ sponsored symposium on the topic of women and the military was first suggested by Dr. Walter Wilkins, then Scientific Director of the Naval Health Research Center, San Diego, California. At that time and during the previous 5 years, increasing numbers of women were being recruited into military service not only in the United States but also in several NATO-allied countries. Few research projects on the utilization of women in the military had been reported in the scientific literature with the exception of work conducted at the University of Chicago and Naval Health Research Center. Several investigators, however, were identified who had recently initiated research in this ...

Comparison of Ares I-X Wind-Tunnel Derived Buffet Environment with Flight Data

Science.gov (United States)

Piatak, David J.; Sekula, Martin K.; Rausch, Russ D.

2011-01-01

The Ares I-X Flight Test Vehicle (FTV), launched in October 2009, carried with it over 243 buffet verification pressure sensors and was one of the most heavily instrumented launch vehicle flight tests. This flight test represented a unique opportunity for NASA and its partners to compare the wind-tunnel derived buffet environment with that measured during the flight of Ares I-X. It is necessary to define the launch vehicle buffet loads to ensure that structural components and vehicle subsystems possess adequate strength, stress, and fatigue margins when the vehicle structural dynamic response to buffet forcing functions are considered. Ares I-X buffet forcing functions were obtained via wind-tunnel testing of a rigid buffet model (RBM) instrumented with hundreds of unsteady pressure transducers designed to measure the buffet environment across the desired frequency range. This paper discusses the comparison of RBM and FTV buffet environments, including fluctuating pressure coefficient and normalized sectional buffet forcing function root-mean-square magnitudes, frequency content of power-spectral density functions, and force magnitudes of an alternating flow phenomena. Comparison of wind-tunnel model and flight test vehicle buffet environments show very good agreement with root-mean-square magnitudes of buffet forcing functions at the majority of vehicle stations. Spectra proved a challenge to compare because of different wind-tunnel and flight test conditions and data acquisition rates. However, meaningful and promising comparisons of buffet spectra are presented. Lastly, the buffet loads resulting from the transition of subsonic separated flow to supersonic attached flow were significantly over-predicted by wind-tunnel results.

Broadband X-ray spectra of the ultraluminous x-ray source Holmberg IX X-1 observed with NuSTAR, XMM-Newton, and Suzaku

DEFF Research Database (Denmark)

Walton, D. J.; Harrison, F. A.; Grefenstette, B. W.

2014-01-01

We present results from the coordinated broadband X-ray observations of the extreme ultraluminous X-ray source Holmberg IX X-1 performed by NuSTAR, XMM-Newton, and Suzaku in late 2012. These observations provide the first high-quality spectra of Holmberg IX X-1 above 10 keV to date, extending the...

Suggestions for Local School District Compliance with Title IX Rules and Regulations.

Science.gov (United States)

Arizona State Dept. of Education, Phoenix.

This guidebook is designed to help local districts determine how well they comply with the spirit of the Title IX requirements against sex discrimination, which in turn could aid in compliance with the letter of the law. The document's first section presents samples of required antidiscrimination policy statements issued by two districts. The…

John B. Little Center Annual Symposium

International Nuclear Information System (INIS)

Demple, Bruce F.

2007-01-01

The Annual Symposium of the John B. Little Center for Radiation Sciences and Environmental Health at the Harvard School of Public Health seeks to educate radiobiologists and biomedical scientists in related areas on the leading research related to the effects of ionizing radiation and related environmental agents in biological systems. This effort seeks to further the training of individuals in this field, and to foment productive interactions and collaborations among scientists at Harvard and with other institutions. The Symposium attracts world-class scientists as speakers, and a broad cross-section of attendees from academic, government, and industrial research centers, as well as editorial staff from leading scientific publications. In order to maintain this quality, funding to support the travel and local expenses of invited speakers is sought, along with funds to allow use of appropriate conference facilities.

John B. Little Center Annual Symposium

Energy Technology Data Exchange (ETDEWEB)

Demple, Bruce F.

2007-11-02

The Annual Symposium of the John B. Little Center for Radiation Sciences and Environmental Health at the Harvard School of Public Health seeks to educate radiobiologists and biomedical scientists in related areas on the leading research related to the effects of ionizing radiation and related environmental agents in biological systems. This effort seeks to further the training of individuals in this field, and to foment productive interactions and collaborations among scientists at Harvard and with other institutions. The Symposium attracts world-class scientists as speakers, and a broad cross-section of attendees from academic, government, and industrial research centers, as well as editorial staff from leading scientific publications. In order to maintain this quality, funding to support the travel and local expenses of invited speakers is sought, along with funds to allow use of appropriate conference facilities.

SYMPOSIUM: Rare decays

Energy Technology Data Exchange (ETDEWEB)

Anon.

1989-04-15

Late last year, a symposium entitled 'Rare Decays' attracted 115 participants to a hotel in Vancouver, Canada. These participants were particle physicists interested in checking conventional selection rules to look for clues of possible new behaviour outside today's accepted 'Standard Model'. For physicists, 'rare decays' include processes that have so far not been seen, explicitly forbidden by the rules of the Standard Model, or processes highly suppressed because the decay is dominated by an easier route, or includes processes resulting from multiple transitions.

Optical Observations of M81 Galaxy Group in Narrow Band [SII] and H_alpha Filters: Holmberg IX

Directory of Open Access Journals (Sweden)

Arbutina, B.

2009-12-01

Full Text Available We present observations of the nearby tidal dwarf galaxy Holmberg IX in M81 galaxy group in narrow band [SII] and H$alpha$ filters, carried out in March and November 2008 with the 2m RCC telescope at NAO Rozhen, Bulgaria. Our search for resident supernova remnants (identified as sources with enhanced [SII] emission relative to their H$alpha$ emission in this galaxy yielded no sources of this kind, besides M&H 10-11 or HoIX X-1. Nevertheless, we found a number of objects with significant H$alpha$ emission that probably represent uncatalogued HII regions.

PREFACE: Padjadjaran Earth Dialogues: International Symposium on Geophysical Issues, PEDISGI

Science.gov (United States)

Rosandi, Y.; Urbassek, H. M.; Yamanaka, H.

2016-01-01

This issue of IOP Conference Series: Earth and Environmental Science contains selected papers presented at the Padjadjaran Earth Dialogues: International Symposium on Geophysical Issues, PEDISGI. The meeting was held from June 8 to 10, 2015, at the Bale-Sawala of Universitas Padjadjaran in Jatinangor, Indonesia. The PEDISGI is a symposium to accommodate communication between researchers, in particular geophysicists and related scientists, and to enable sharing of knowledge and research findings concerning local and global geophysical issues. The symposium was attended by 126 participants and 64 contributors from Indonesian universities and the neighbouring countries in four categories, viz. Theoretical and Computational Geophysics, Environmental Geophysics, Geophysical Explorations, and Geophysical Instrumentations and Methods. The symposium was accompanied by a dialog, discussing a chosen topic regarding environmental and geological problems of relevance for the Indonesian archipelago and the surrounding regions. For this first event the topic was ''The formation of Bandung-Basin between myths and facts: Exemplary cultural, geological and geophysical study on the evolution of the earth surface'', presented by invited speakers and local experts. This activity was aimed at extending our knowledge on this particular subject, which may have global impact. This topic was augmented by theoretical background lectures on the earth's surface formation, presented by the invited speakers of the symposium. The meeting would not have been successful without the assistance of the local organizing committee. We want to specially thank Irwan A. Dharmawan for managing the programme, Anggie Susilawati and Mia U. Hasanah for the conference administration, and Dini Fitriani for financial management. We also thank the National Geographic Indonesia for its support via the Business to Business Collaboration Program. The conference photograph can be viewed in the PDF.

NDIA 2018 IM and EM Technology Symposium: Innovative Insensitive Munition Solutions for Enhanced Warfighter Effectiveness

Science.gov (United States)

2018-04-26

2018 IM & EM TECHNOLOGY SYMPOSIUM INNOVATIVE INSENSITIVE MUNITION SOLUTIONS FOR ENHANCED WARFIGHTER EFFECTIVENESS April 23 – 26, 2018 Doubletree by...IM & EM TECHNOLOGY SYMPOSIUM On behalf of the Insensitive Munitions and Energetic Materials Committee and our MSIAC partner, I would like to...welcome you to the 2018 Insensitive Munitions and Energetic Materials Technology Symposium. This international gathering of the top chemists, system

International Symposium on Disarmament Education: A Report. Proceedings from a World Confederation of Organizations of the Teaching Profession and Japan Teachers Union Symposium (Hiroshima, Japan, October 25-29, 1982).

Science.gov (United States)

Japan Teachers Union, Tokyo.

Proceedings from an international symposium devoted to the cause of disarmament education are presented. Representatives from international and national teacher organizations together with scholars and researchers from 35 countries and all continents attended. The symposium focused on the idea that teachers have a special responsibility to work…

Proceedings of the symposium on frontier nuclear physics (FRONP99)

International Nuclear Information System (INIS)

Chiba, Satoshi

2000-01-01

The symposium on Frontier Nuclear Physics (FRONP99), organized by the Research Group for Hadron Science, Advanced Science Research Center, under close cooperation with the Research Center for Nuclear Physics, Osaka University and High Energy Accelerator Research Organization, was held at Tokai Research Establishment of JAERI on August 2 to 4, 1999. The symposium was devoted for discussions and presentations of research results in wide variety of fields such as hyper nuclear physics, lepton nuclear physics, quark nuclear physics, unstable nuclear physics, superheavy elements and heavy-ion physics. Three talks on the joint project between JAERI (Neutron Science Research Center) and KEK (JHF) were presented in a public session. Thirty three talks on these topics presented at the symposium aroused lively discussions among approximately 70 participants. This report contains 26 papers submitted from the lecturers. (author)

5th International Symposium on Experimental Mechanics (5-ISEM) and 9th Symposium on Optics in Industry

CERN Document Server

Furlong, Cosme; Barrientos, Bernardino; Pryputniewicz, Ryszard

2017-01-01

This book contains papers of the 5th International Symposium on Experimental Mechanics (5-ISEM) and the 9th Symposium on Optics in Industry (9-SOI), whose general theme is Emerging Challenges for Experimental Mechanics in Energy and Environmental Applications. These symposia are organized by Centro de Investigaciones en Optica (CIO) and Mexican Academy for Optics (AMO), under the sponsorship of the Society of Experimental Mechanics (SEM) and other national and international Organizations; Symposia are interdisciplinary forums for engineers, technicians, researchers and managers involved in all fields of Optics, Opto-mechatronics, Mechanics and Mechanical Engineering. · Addresses a broad readership including graduate and postgraduate students, researchers, and engineers working in experimental mechanics and in the application of optical methods · Covers a broad spectrum of topics highlighting the use of optical methods in experimental mechanics, energy, and in the environment.

Sensitizing properties of proteins

DEFF Research Database (Denmark)

Poulsen, Lars K.; Ladics, Gregory S; McClain, Scott

2014-01-01

The scope of allergy risk is diverse considering the myriad ways in which protein allergenicity is affected by physiochemical characteristics of proteins. The complexity created by the matrices of foods and the variability of the human immune system add additional challenges to understanding...... the relationship between sensitization potential and allergy disease. To address these and other issues, an April 2012 international symposium was held in Prague, Czech Republic, to review and discuss the state-of-the-science of sensitizing properties of protein allergens. The symposium, organized by the Protein...... Allergenicity Technical Committee of the International Life Sciences Institute's Health and Environmental Sciences Institute, featured presentations on current methods, test systems, research trends, and unanswered questions in the field of protein sensitization. A diverse group of over 70 interdisciplinary...

The rates and patterns of deletions in the human factor IX gene

Energy Technology Data Exchange (ETDEWEB)

Ketterling, R.P.; Vielhaber, E.L.; Lind, T.J.; Thorland, E.C.; Sommer S.S. (Mayo Clinic/Foundation, Rochester, MN (United States))

1994-02-01

Deletions are commonly observed in genes with either segments of highly homologous sequences or excessive gene length. However, in the factor IX gene and in most genes, deletions (of [ge]21 bp) are uncommon. The authors have analyzed DNA from 290 families with hemophilia B (203 independent mutations) and have found 12 deletions >20 bp. Eleven of these are >2 kb (range >3-163 kb), and one is 1.1 kb. The junctions of the four deletions that are completely contained within the factor IX gene have been determined. A novel mutation occurred in patient HB128: the data suggest that a 26.8-kb deletion occurred between two segments of alternating purines and pyrimidines and that a 2.3-kb sense strand segment derived from the deleted region was inserted. For a sample of 203 independent mutations, the authors estimate the [open quotes]baseline[close quotes] rates of deletional mutation per base pair per generation as a function of size. The rate for large (>2 kb)I deletions is exceedingly low. For every mutational event in which a given base is at the junction of a large deletion, there are an estimated 58 microdeletions (<20 bp) and 985 single-base substitutions at that base. Analysis of the nine reported deletion junctions in the factor IX gene literature reveals that (i) five are associated with inversion, orphan sequences, or sense strand insertions; (ii) four are simple deletions that display an excess of short direct repeats at their junctions; (iii) there is no dramatic clustering of junctions within the gene; and (iv) with the exception of alternating purines and pyrimidines, deletion junctions are not preferentially associated with repetitive DNA. 58 refs., 5 figs., 5 tabs.

Ninth International Symposium on Recent Advances in Environmental Health Research

Directory of Open Access Journals (Sweden)

Paul B. Tchounwou

2014-01-01

Full Text Available This special issue of International Journal of Environmental Research and Public Health is dedicated to the publication of selected papers presented at the Eighth International Symposium on Recent Advances in Environmental Health Research. The Symposium was organized by Jackson State University (JSU from 16–19 September, 2012 at the Marriott Hotel in Jackson, Mississippi, USA. It was built upon the overwhelming success of seven previous symposia hosted by JSU.

Symposium proceedings: environmental aspects of fuel conversion technology, IV (April 1979, Hollywood, FL)

Energy Technology Data Exchange (ETDEWEB)

Ayer, F.A.; Jones, N.S. (comps.)

1979-09-01

The proceedings document presentations made at the symposium on Environmental Aspects of Fuel Conversion Technology are presented. The symposium acted as a colloquium for discussion of environmentally related information on coal gasification and liquefaction. The program included sessions on program approach, environmental assessment, and control technology development. Process developers, process users, research scientists and state and federal government officials participated in this symposium, the fourth to be conducted by IERL-RTP on the subject since 1974. Separate abstracts have been prepared of individual presentations for inclusion in the Energy Data Base.

4. Danish symposium in analytical chemistry

International Nuclear Information System (INIS)

1996-01-01

At the 4th Danish Symposium of Analytical Chemistry 11 lectures and 32 posters were presented during two session days on the 20 and 21 August 1996. Various analytical techniques were discussed for foodstuff, pesticide, pharmaceutical, industrial and other analyses. (EG)

The Wharton Symposium: Facing the Issues.

Science.gov (United States)

Sullivan, David M.

1982-01-01

A public relations practitioner reports enthusiastically on his return to the campus for an "intellectually-broadening" public relations symposium. He summarizes critical social and economic issues addressed by distinguished scholars and experienced practitioners. For journal availability, see CS 705 902. (PD)

Title IX, Girls' Sports Participation, and Adult Female Physical Activity and Weight

Science.gov (United States)

Kaestner, Robert; Xu, Xin

2010-01-01

Arguably, the most important school-based intervention to increase physical activity was Title IX of the Education Amendments of 1972, which led to a 600% increase in girls' sports participation between 1972 and 1978. We studied the effect of this increase in sports participation and athletic opportunities while young on the physical activity and…

Roundtable discussion on the Third Global Symposium on Health Systems Research

DEFF Research Database (Denmark)

Lazarus, Jeffrey V; Balabanova, Dina; Safreed-Harmon, Kelly

2015-01-01

Health systems experts from around the world discuss why they were meeting at the Third Global Symposium on Health Systems Research while people were dying of Ebola in West Africa.......Health systems experts from around the world discuss why they were meeting at the Third Global Symposium on Health Systems Research while people were dying of Ebola in West Africa....

Proceedings of 8th Symposium of the Croatian Radiation Protection Association

Energy Technology Data Exchange (ETDEWEB)

Krajcar Bronic, I; Kopjar, N; Milic, M; Branica, G

2011-07-01

The 8th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; public exposure; biological effects of radiation; radiation protection in medicine; radioecology and non-ionizing radiation. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

Proceedings of 8th Symposium of the Croatian Radiation Protection Association

International Nuclear Information System (INIS)

Krajcar Bronic, I.; Kopjar, N.; Milic, M.; Branica, G.

2011-01-01

The 8th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; public exposure; biological effects of radiation; radiation protection in medicine; radioecology and non-ionizing radiation. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

Proceedings of 9th Symposium of the Croatian Radiation Protection Association

International Nuclear Information System (INIS)

Knezevic, Z.; Krajcar Bronic, I.; Majer, M.

2013-01-01

The 9th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry; public exposure; biological effects of radiation; radiation protection in medicine; radioecology and instrumentation and measuring techniques. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

Proceedings of the 1994 nuclear simulation symposium

Energy Technology Data Exchange (ETDEWEB)

Laughton, P J [ed.; Atomic Energy of Canada Ltd., Chalk River, ON (Canada). Chalk River Nuclear Labs.

1994-12-31

This symposium on nuclear simulation included sessions on reactor physics, on thermalhydraulics, and on fuel and fuel channels of CANDU type reactors. The individual papers have all been abstracted separately.

Indian symposium reviews tsunami response

Directory of Open Access Journals (Sweden)

Paula Banerjee

2005-07-01

Full Text Available A symposium of academics and human rights activists organised by the Calcutta Research Group assessed the extent to which relief and rehabilitation initiatives in Tamil Nadu and the Andaman and Nicobar islands have recognised the rights of those affected to receive aid without discrimination based on caste, religion or gender.

MEMORIAL SYMPOSIUM:
Willi Jentschke

CERN Multimedia

CERN. Geneva

2002-01-01

- Welcome by L. Maiani - Message from DESY by E. Lohrmann - Willi Jentschke by H. Schopper - The Neutral Currents by M. Veltman and D. Perkins - The ISR in Jentschke's time by K. Johnsen - Some recollections of Jentschke by K. WinterNote: Participants are cordially invited to drinks at 17h.30 following the symposium

12. Kassel symposium of power system engineering - control technology for decentral power supply systems. Proceedings; Zwoelftes Kasseler Symposium Energie-Systemtechnik - Regelungstechnik fuer dezentrale Energiesysteme. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

The 12. Kassel symposium of power system engineering focused on control technology for decentral power generation systems. It addressed experts of mechanical engineering, electrical engineering, control engineering and related fields. The symposium was to provide a picture of the state of the art of selected control systems and also to illustrate the immportance of control technology for these systems. Most of the papers used the example of large-capacity wind power systems, where the interdependence of mechanical and electrical engineering and the importance of control technology are particularly clear. The selected illustrate the interdisciplinary character of this engineering discipline, which is also the element that makes it so very interesting. The Kassel symposium therefore addressed not only experts but also students of these disciplines who want to find out more about the theory and practice of renewable power systems. (orig.)

Quark matter coupled to domain walls in Bianchi types II, VIII and IX ...

Indian Academy of Sciences (India)

In this study of Bianchi types II, VIII and IX Universes, quark matter coupled to domain walls in the context of general relativity are explored. To obtain deterministic solution of the Einstein's field equations, various techniques are adopted. The features of the obtained solution are discussed.

Bianchi - I, II, VIII, IX and Kantowski-Sachs-like cosmological models with perfect fluid and electromagnetic fields with conductivity current

International Nuclear Information System (INIS)

Portugal, R.

1984-01-01

Three processes of solutions of the Einstein-Maxwell equations for Bianchi - I, II, VIII, IX and Kantowski-Sachs-like cosmological models with perfect fluid in magnetohydrolodynamical regimem are presented. Diagonal Bianchi-like models are considered with two anisotropy direction in the maximum. Solutions are found for Bianchi-II and IX-like models with energy conditions to be analyzed. Solutions are found for Bianchi-IX and Kantowski-Sachs-Like models with positive electric conductivity and satisfering to the predominant energy conditions. Solutions are formed for isotropic Kantowski-Sachs-Like models satisfering to the equation of state p=λρ, 0 0, admiting, in addition to the perfect fluid, electric field only. It is shown that a class of Bertotti-Robinson-like solutions is unstable by perturbations and it is carried in Kantowski-Sachs-like models with non-null electric conductivity. (L.C.) [pt

Proceedings of the symposium on leukemia clustering

Energy Technology Data Exchange (ETDEWEB)

Elaguppillai, V [Atomic Energy Control Board, Ottawa, ON (Canada); Goyette, J P [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection; Hill, G; Krewski, D [Department of National Health and Welfare, Ottawa, ON (Canada); Osborne, R V [Atomic Energy of Canada Ltd., Chalk River, ON (Canada). Chalk River Nuclear Labs.

1992-07-01

Clusters of leukemia in populations living in specific locations in various countries have been examined by scientific and medical experts for many years. In general, the reason for the existence of these clusters is unknown. The recent discovery of a small cluster of leukemias among children who were born in the vicinity of a nuclear fuel reprocessing facility in England has stimulated wide interest in the possible occurrence of clusters of leukemia around nuclear facilities. The purpose of this symposium was to present scientific evidence concerning the existence of leukemia clusters in the population, to discuss possible causes for these clusters and to suggest directions for future research. Distinguished speakers from Canada, the United Kingdom, Germany, Italy and the U.S.A. participated in this symposium. (author).

Proceedings of the symposium on leukemia clustering

International Nuclear Information System (INIS)

Elaguppillai, V.; Goyette, J.P.; Osborne, R.V.

1992-07-01

Clusters of leukemia in populations living in specific locations in various countries have been examined by scientific and medical experts for many years. In general, the reason for the existence of these clusters is unknown. The recent discovery of a small cluster of leukemias among children who were born in the vicinity of a nuclear fuel reprocessing facility in England has stimulated wide interest in the possible occurrence of clusters of leukemia around nuclear facilities. The purpose of this symposium was to present scientific evidence concerning the existence of leukemia clusters in the population, to discuss possible causes for these clusters and to suggest directions for future research. Distinguished speakers from Canada, the United Kingdom, Germany, Italy and the U.S.A. participated in this symposium. (author)

2nd International Symposium "Atomic Cluster Collisions : Structure and Dynamics from the Nuclear to the Biological Scale"

CERN Document Server

Solov'yov, Andrey; ISACC 2007; Latest advances in atomic cluster collisions

2008-01-01

This book presents a 'snapshot' of the most recent and significant advances in the field of cluster physics. It is a comprehensive review based on contributions by the participants of the 2nd International Symposium on Atomic Cluster Collisions (ISACC 2007) held in July 19-23, 2007 at GSI, Darmstadt, Germany. The purpose of the Symposium is to promote the growth and exchange of scientific information on the structure and properties of nuclear, atomic, molecular, biological and complex cluster systems studied by means of photonic, electronic, heavy particle and atomic collisions. Particular attention is devoted to dynamic phenomena, many-body effects taking place in cluster systems of a different nature - these include problems of fusion and fission, fragmentation, collective electron excitations, phase transitions, etc.Both the experimental and theoretical aspects of cluster physics, uniquely placed between nuclear physics on the one hand and atomic, molecular and solid state physics on the other, are discuss...

Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets.

Science.gov (United States)

Mangin, P H; Receveur, N; Wurtz, V; David, T; Gachet, C; Lanza, F

2009-09-01

Binding of von Willebrand factor to the platelet glycoprotein (GP)Ib-IX complex initiates a signaling cascade leading to integrin alpha(IIb)beta(3) activation, a key process in hemostasis and thrombosis. Interaction of 14-3-3zeta with the intracytoplasmic domain of GPIb appears to be a major effector of this activation pathway. The aim of our study was to determine whether other members of the 14-3-3 family bind to GPIb-IX. In this study, western blot analyses showed that platelets also contain the 14-3-3beta, 14-3-3gamma, 14-3-3epsilon, 14-3-3eta and 14-3-3theta isoforms, but lack 14-3-3sigma. Coimmunoprecipitation studies in platelets and CHO transfectants demonstrated that all six 14-3-3 isoforms expressed in platelets, including, as previously reported, 14-3-3zeta, bind to GPIb-IX. In addition, their interaction was found to critically require the same GPIbalpha domains (580-590 and 605-610) already identified as essential for 14-3-3zeta binding, in agreement with the conservation of the sequence of the I-helix among these different isoforms. Pull-down experiments indicated that all six 14-3-3 isoforms present in platelets bind to GPIbbeta. In contrast, deletion or mutation of the GPIbbeta intracytoplasmic tail did not affect the interaction of GPIb-IX with the 14-3-3 isoforms, questioning the importance of this domain. Our study suggests that, to inhibit GPIb-induced integrin alpha(IIb)beta(3) activation, a more appropriate strategy than inhibiting individual 14-3-3 isoforms would be to target the 14-3-3-binding motif on GPIb or, alternatively, the conserved 14-3-3 I-helix.

Revisitation of chaos in Bianchi IX Universe and in generalized scalar-tensor cosmologies

International Nuclear Information System (INIS)

Lehner, Thierry; Di Menza, Laurent

2003-01-01

We show that there is a threshold for the onset of chaos in cosmology for the Universe described as a dynamical system derived from the Einstein equations of general relativity (GR). In the case of the mixmaster model (homogeneous and anisotropic cosmology with a Bianchi IX metric) the chaos occurs precisely at the prescribed necessary value H vac =0 of the GR for the energy of the Universe while the system is found regular for H vac >0 and chaotic for H vac <0 with respect to its pure vacuum part. In the case of generalized scalar tensor theories within the Bianchi IX model we show using the ADM formalism and a conformal transformation that the energy of the dynamical system as compared to vacuum lies below the threshold thus the system is not exhibiting chaos and the conclusion still holds in the presence of ordinary matter as well. The suppression of chaos occurs in a similar way for stiff matter alone

CUBE (Computer Use By Engineers) symposium abstracts

International Nuclear Information System (INIS)

Ruminer, J.J.

1978-07-01

This report presents the abstracts for the CUBE (Computer Use by Engineers) Symposium, October 4, through 6, 1978. Contributors are from Lawrence Livermore Laboratory, Los Alamos Scientific Laboratory, and Sandia Laboratories

SYMPOSIUM ON TURBULENCE AND COMBUSTION - SPECIAL SYMPOSIUM TO BRING TOGETHER TOP RESEARCHERS IN THE FIELDS OF FLUID TURBULENCE AND COMBUSTION TO PROMOTE ADVANCES IN TURBULENT, REACTING FLOWS

Energy Technology Data Exchange (ETDEWEB)

Caughey, David

2010-10-08

A Symposium on Turbulence and Combustion was held at Cornell University on August 3-4, 2009. The overall goal of the Symposium was to promote future advances in the study of turbulence and combustion, through an unique forum intended to foster interactions between leading members of these two research communities. The Symposium program consisted of twelve invited lectures given by world-class experts in these fields, two poster sessions consisting of nearly 50 presentations, an open forum, and other informal activities designed to foster discussion. Topics covered in the lectures included turbulent dispersion, wall-bounded flows, mixing, finite-rate chemistry, and others, using experiment, modeling, and computations, and included perspectives from an international community of leading researchers from academia, national laboratories, and industry.

Summary of 2 nd Nordic symposium on digital pathology

Directory of Open Access Journals (Sweden)

Claes Lundström

2015-01-01

Full Text Available Techniques for digital pathology are envisioned to provide great benefits in clinical practice, but experiences also show that solutions must be carefully crafted. The Nordic countries are far along the path toward the use of whole-slide imaging in clinical routine. The Nordic Symposium on Digital Pathology (NDP was created to promote knowledge exchange in this area, between stakeholders in health care, industry, and academia. This article is a summary of the NDP 2014 symposium, including conclusions from a workshop on clinical adoption of digital pathology among the 144 attendees.

Summary of 2nd Nordic symposium on digital pathology

Science.gov (United States)

Lundström, Claes; Thorstenson, Sten; Waltersson, Marie; Persson, Anders; Treanor, Darren

2015-01-01

Techniques for digital pathology are envisioned to provide great benefits in clinical practice, but experiences also show that solutions must be carefully crafted. The Nordic countries are far along the path toward the use of whole-slide imaging in clinical routine. The Nordic Symposium on Digital Pathology (NDP) was created to promote knowledge exchange in this area, between stakeholders in health care, industry, and academia. This article is a summary of the NDP 2014 symposium, including conclusions from a workshop on clinical adoption of digital pathology among the 144 attendees. PMID:25774316

Summary of 2(nd) Nordic symposium on digital pathology.

Science.gov (United States)

Lundström, Claes; Thorstenson, Sten; Waltersson, Marie; Persson, Anders; Treanor, Darren

2015-01-01

Techniques for digital pathology are envisioned to provide great benefits in clinical practice, but experiences also show that solutions must be carefully crafted. The Nordic countries are far along the path toward the use of whole-slide imaging in clinical routine. The Nordic Symposium on Digital Pathology (NDP) was created to promote knowledge exchange in this area, between stakeholders in health care, industry, and academia. This article is a summary of the NDP 2014 symposium, including conclusions from a workshop on clinical adoption of digital pathology among the 144 attendees.