Bupropion XL-induced motor and vocal tics.

Science.gov (United States)

Kayhan, Fatih; Uguz, Faruk; Kayhan, Ayşegül; Toktaş, Fikriye Ilay

2014-01-01

Tics are stereotypical repetitive involuntary movements (motor tics) or sounds (vocal tics). Although the emergence of tics were reported in a few cases with the use of selective serotonin reuptake inhibitors, there was no case with bupropion extended-release (Bupropion XL). The current case report presents a male patient developing motor and vocal tics with the use of bupropion XL.

New Meteorlogical Data for Ventsar XL

Energy Technology Data Exchange (ETDEWEB)

T. Foley; Jannik, T.

2010-06-13

Every five years Savannah River National Laboratory (SRNL) generates an updated meteorological database to facilitate dosimetric calculations of accident and routine release scenarios for onsite and offsite populations. This information becomes the input of various environmental dosimetry codes run by the Environmental Dosimetry Group (EDG) at SRNL. The three most recent databases prior to the current one were completed for the time periods 1987-1991, 1992-1996, and 1997-2001. The current database covers the period 2002-2006. This study represents a portion of a larger study to compare the meteorological data among these four five-year periods and focuses on updating VENTSAR XL{copyright} for the current meteorological database. The updated meteorological data are also applied in other dosimetry models approved for risk and dose assessment at Savannah River Site (SRS). VENTSAR XL{copyright} is a Gaussian Plume model that includes building effects and plume rise. The typical input involves the location of the release, building dimensions, distance to the building, release height, vent diameter, vent gas temperature, gas molecular weight, ambient air temperature, breathing rate, meteorological conditions, radionuclides and their amount released. The output is easily converted into tables and graphs for further analysis and shows the concentrations and pathway doses for each of the incremental downwind distances. VENTSAR XL{copyright} has been used at SRS to investigate building effects such as reactor cooling towers in support of safety analyses. VENTSAR XL{copyright} has also been applied to Good Engineering Practice (GEP) stack height evaluations for various projects at SRS. In accordance with the Clean Air Act Amendments of 1977, GEP must be used in determining the height of any stack that will be used to disperse routine emissions. With respect to stack heights, the GEP height is 'the height necessary to ensure that emissions from the stack do not result in

IBM model M keyboard

CERN Multimedia

1985-01-01

In 1985, the IBM Model M keyboard was created. This timeless classic was a hit. IBM came out with several varients of the model M. They had the space saver 104 key which is the one most seen today and many international versions of that as well. The second type, and rarest is the 122 key model M which has 24 extra keys at the very top, dubbed the “programmers keyboard”. IBM manufactured these keyboards until 1991. The model M features “caps” over the actual keys that can be taken off separately one at a time for cleaning or to replace them with colored keys or keys of another language, that was a very cost effective way of shipping out internationally the keyboards.

Software Process Improvement Journey: IBM Australia Application Management Services

Science.gov (United States)

2005-03-01

See Section 5.1.2) - Client Relationship Management ( CRM ) processes-specifically, Solution Design and Solution Delivery - Worldwide Project Management ...plex systems life-cycle management , rapid solutions development, custom development, package selection and implementation, maintenance, minor...CarnegieMellon ___ Software Engineering Institute Software Process Improvement Journey: IBM Australia Application Management Services Robyn Nichols

Data Mining and Knowledge Discover - IBM Cognitive Alternatives for NASA KSC

Science.gov (United States)

Velez, Victor Hugo

2016-01-01

Skillful tools in cognitive computing to transform industries have been found favorable and profitable for different Directorates at NASA KSC. In this study is shown how cognitive computing systems can be useful for NASA when computers are trained in the same way as humans are to gain knowledge over time. Increasing knowledge through senses, learning and a summation of events is how the applications created by the firm IBM empower the artificial intelligence in a cognitive computing system. NASA has explored and applied for the last decades the artificial intelligence approach specifically with cognitive computing in few projects adopting similar models proposed by IBM Watson. However, the usage of semantic technologies by the dedicated business unit developed by IBM leads these cognitive computing applications to outperform the functionality of the inner tools and present outstanding analysis to facilitate the decision making for managers and leads in a management information system.

8-inch IBM floppy disk

CERN Multimedia

1971-01-01

The 8-inch floppy disk was a magnetic storage disk for the data introduced commercially by IBM in 1971. It was designed by an IBM team as an inexpensive way to load data into the IBM System / 370. Plus it was a read-only bare disk containing 80 KB of data. The first read-write version was introduced in 1972 by Memorex and could contain 175 KB on 50 tracks (with 8 sectors per track). Other improvements have led to various coatings and increased capacities. Finally, it was surpassed by the mini diskette of 5.25 inches introduced in 1976.

The Early Overseas Activities of IBM in Japan

OpenAIRE

吉沢, 正広; 田中, 雅章; Masahiro, YOSHIZAWA; Masaaki, TANAKA; 愛知学院大学; 鈴鹿短期大学; / SUZUKA JUNIOR COLLEGE

1998-01-01

The purpose of this paper is to examine how IBM entered into prewar Japan and ran its wholly-owned subsidiary thereafter. Before examining something noted above, this paper surveys the process of formation of IBM and then traces its early overseas activities. Turning to the initial contacts between Japan and IBM, at first IBM carried out its mere export trade to Japan through Morimura and then Kurosawa. IBM then established its wholly-owned subsidiary, Japan Watson,in Japan to expand the busi...

Atomic structure calculations of Mo XV-XL

International Nuclear Information System (INIS)

Kubo, Hirotaka; Sugie, Tatsuo; Shiho, Makoto; Suzuki, Yasuo; Ishii, Keishi; Maeda, Hikosuke.

1986-06-01

Energy levels and oscillator strengths were calculated for Mo XV - Mo XL. The computer program for atomic structure calculation, developed by Dr. Robert D. Cowan, Los Alamos National Laboratory, was used in the present work. The scaled energy parameters were empirically determined from the observed spectral data. We present wavelengths and transition probabilities of Mo XV-XL. Energy levels and spectral patterns are presented in figures that are useful for the identification of spectral lines. (author)

3XL

DEFF Research Database (Denmark)

Liu, Xiufeng; Thomsen, Christian; Pedersen, Torben Bach

2011-01-01

An increasing number of (semantic) web applications store a very large number of (subject, predicate, object) triples in specialized storage engines called triple-stores. Often, triple-stores are used mainly as plain data stores, i.e., for inserting and retrieving large amounts of triples, but no....../or predicate is known. Extensive experiments with a PostgreSQL-based implementation show that 3XL performs very well for such operations and that the performance is comparable to state-of-the-art triple-stores....

IBM eile, täna ja homme / Kalle Kose

Index Scriptorium Estoniae

Kose, Kalle

2007-01-01

Infotehnoloogiafirma IBM arengust. Lisatud joonised: PC tootjate turuosad (1984-2004); IBM-i käive segmentide lõikes (2000-2005); IBM-i käive kvartaalselt. Vt. ka lk.13: IBM püstitas patentide rekordi

Integrating Closed-loop Supply Chains and Spare Parts Management at IBM

NARCIS (Netherlands)

M. Fleischmann (Moritz); J.A.E.E. van Nunen (Jo); B. Graeve

2002-01-01

textabstractEver more companies are recognizing the benefits of closed-loop supply chains that integrate product returns into business operations. IBM has been among the pioneers seeking to unlock the value dormant in these resources. We report on a project exploiting product returns as a source of

Penerapan Balanced Scorecard untuk Menilai Kinerja PT XL Axiata Tbk dalam Mencapai Strateginya

Directory of Open Access Journals (Sweden)

Kartika Dewi

2015-08-01

Full Text Available This research is conducted to evaluate performance of PT XL Axiata Tbk using Balanced Score Card. The writer made design and implemented BSC in PT XL Axiata Tbk to convince its vision, mision and strategies are alligned. The method of this research is qualitative descriptive. Primary data were teken through questioners and interviewed with employees and customers.Secondary data were taken from annual report published at company website.The result of this research for Financial Perspective is PT XL Axiata Tbk needs to improve its financial ratio, The result of this research for Customer Perspective is PT XL Axiata Tbk needs to improve its customer satisfaction, The result of this research for Internal Business Process Perspective is PT XL Axiata Tbk needs to maintenance its good result, The result of this research for Learning and Growth is PT XL Axiata Tbk needs to maintenance good working environment. The final conclusion from this research at PT XL Axiata Tbk proved the company performance works toward its strategy, make a continous improvement and make a stable profit through the years taken as a sample.

IBM SmartCloud essentials

CERN Document Server

Schouten, Edwin

2013-01-01

A practical, user-friendly guide that provides an introduction to cloud computing using IBM SmartCloud, along with a thorough understanding of resource management in a cloud environment.This book is great for anyone who wants to get a grasp of what cloud computing is and what IBM SmartCloud has to offer. If you are an IT specialist, IT architect, system administrator, or a developer who wants to thoroughly understand the cloud computing resource model, this book is ideal for you. No prior knowledge of cloud computing is expected.

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.

Science.gov (United States)

Speir, Mary; Lawlor, Kate E; Glaser, Stefan P; Abraham, Gilu; Chow, Seong; Vogrin, Adam; Schulze, Keith E; Schuelein, Ralf; O'Reilly, Lorraine A; Mason, Kylie; Hartland, Elizabeth L; Lithgow, Trevor; Strasser, Andreas; Lessene, Guillaume; Huang, David C S; Vince, James E; Naderer, Thomas

2016-02-24

Human pathogenic Legionella replicate in alveolar macrophages and cause a potentially lethal form of pneumonia known as Legionnaires' disease(1). Here, we have identified a host-directed therapeutic approach to eliminate intracellular Legionella infections. We demonstrate that the genetic deletion, or pharmacological inhibition, of the host cell pro-survival protein BCL-XL induces intrinsic apoptosis of macrophages infected with virulent Legionella strains, thereby abrogating Legionella replication. BCL-XL is essential for the survival of Legionella-infected macrophages due to bacterial inhibition of host-cell protein synthesis, resulting in reduced levels of the short-lived, related BCL-2 pro-survival family member, MCL-1. Consequently, a single dose of a BCL-XL-targeted BH3-mimetic therapy, or myeloid cell-restricted deletion of BCL-XL, limits Legionella replication and prevents lethal lung infections in mice. These results indicate that repurposing BH3-mimetic compounds, originally developed to induce cancer cell apoptosis, may have efficacy in treating Legionnaires' and other diseases caused by intracellular microbes.

A Synthesis of Hybrid RANS/LES CFD Results for F-16XL Aircraft Aerodynamics

Science.gov (United States)

Luckring, James M.; Park, Michael A.; Hitzel, Stephan M.; Jirasek, Adam; Lofthouse, Andrew J.; Morton, Scott A.; McDaniel, David R.; Rizzi, Arthur M.

2015-01-01

A synthesis is presented of recent numerical predictions for the F-16XL aircraft flow fields and aerodynamics. The computational results were all performed with hybrid RANS/LES formulations, with an emphasis on unsteady flows and subsequent aerodynamics, and results from five computational methods are included. The work was focused on one particular low-speed, high angle-of-attack flight test condition, and comparisons against flight-test data are included. This work represents the third coordinated effort using the F-16XL aircraft, and a unique flight-test data set, to advance our knowledge of slender airframe aerodynamics as well as our capability for predicting these aerodynamics with advanced CFD formulations. The prior efforts were identified as Cranked Arrow Wing Aerodynamics Project International, with the acronyms CAWAPI and CAWAPI-2. All information in this paper is in the public domain.

IBM PC enhances the world's future

Science.gov (United States)

Cox, Jozelle

1988-01-01

Although the purpose of this research is to illustrate the importance of computers to the public, particularly the IBM PC, present examinations will include computers developed before the IBM PC was brought into use. IBM, as well as other computing facilities, began serving the public years ago, and is continuing to find ways to enhance the existence of man. With new developments in supercomputers like the Cray-2, and the recent advances in artificial intelligence programming, the human race is gaining knowledge at a rapid pace. All have benefited from the development of computers in the world; not only have they brought new assets to life, but have made life more and more of a challenge everyday.

Isospin invariant forms of interacting boson model (IBM)

International Nuclear Information System (INIS)

Evans, A.

1989-01-01

In the original version of the interacting boson model, IBM1, there are only two quantum numbers with exact values: the angular momentum and the number of bosons. IBM2 distinguishes between two kinds of bosons. However, the IBM2 algebra does not include the operators T± and consequently the states in the model have no good isospin, generally. IBM3 includes the isospin in the algebra and therefore the construction of states with any number of bosons and good isospin presents no problem. In this work, IBM3 is compared with the shell model. IBFM3 is also studied, which describes an odd nucleus as a system of N bosons plus a single nucleon that is a neutron with some probability and a proton with the complementary probability. The spectra obtained in the shell model, IBFM3 and IBFM2 for 45 Ti and 45 Sc are compared. (Author) [es

International Border Management Systems (IBMS) Program : visions and strategies.

Energy Technology Data Exchange (ETDEWEB)

McDaniel, Michael; Mohagheghi, Amir Hossein

2011-02-01

Sandia National Laboratories (SNL), International Border Management Systems (IBMS) Program is working to establish a long-term border security strategy with United States Central Command (CENTCOM). Efforts are being made to synthesize border security capabilities and technologies maintained at the Laboratories, and coordinate with subject matter expertise from both the New Mexico and California offices. The vision for SNL is to provide science and technology support for international projects and engagements on border security.

IBM 3380 E

CERN Multimedia

1985-01-01

In 1985 IBM announced a double density version. The Extended Capability Models of the 3380 (3380 E) having 5.04 gigabytes per chassis, that is, two 1.26 gigabyte actuators on two hard disk assemblies in one chassis.

Lenovo acquires IBM's x86 low-end server business

Directory of Open Access Journals (Sweden)

Singh Pal Netra

2015-01-01

Full Text Available This paper presents an analysis of the key events, impacts and issues of Lenovo buying IBM's x86 low-end server business. The analysis include (i approval of the deal by regulatory bodies in the United States, Canada, India and China, (ii security concerns of US government departments, (iii pricing of the deals, (iv possible impact on IBM in future, and (v possibilities of Lenovo making it repeat of acquiring ThinkPad business of IBM. The paper presents analysis of qualitative and time series quantitative data. The qualitative data are mainly consists of different events before and after the acquisition of x86 server IBM business by Lenovo. The quantitative data are analyzed with respect to growth parameters of overall server business and Lenovo server business. Research paper also attempts to find out answer to specific 9 research questions with respect to impact on eco-systems of IBM and Lenovo. Based on analysis, it is inferred that IBM is not able to manage its traditional & well accepted products business in the face of fierce competition & low demand but Lenovo will manage. The deal was a financial necessity for IBM and strategic expansion in to new markets strategy for Lenovo.

[IBM Work and Personal Life Balance Programs.

Science.gov (United States)

International Business Machines Corp., Armonk, NY.

These five brochures describe the IBM Corporation's policies, programs, and initiatives designed to meet the needs of employees' child care and family responsibilities as they move through various stages of employment with IBM. The Work and Personal Life Balance Programs brochure outlines (1) policies for flexible work schedules, including…

IBM Industry Practice: Challenges in Offshore Software Development from a Global Delivery Center

Science.gov (United States)

Musio, Ilario

Offshore software development has greatly influenced competitiveness among IT companies in the last decade. Despite the fact that there are matured and developed offshoring methodologies, there is an ongoing tendency to look for new ways of improving them. Major IT corporations successfully rely on their offshore delivery centers for bridging the gap between communication and infrastructure boundaries. However, projects tend to fail, so problems have to be considered that arise between on- and offshore parts within the same corporation. Based on seven case studies from the industry, this paper describes experiences and challenges faced during the execution of offshore application development between IBM Switzerland and IBM India. Additionally, approaches on how they can be solved are proposed.

S, M, L, XL: SEBUAH PANDANGAN PERALIHAN MODERN URBANISME MENUJU POSTMODERN URBANISME

Directory of Open Access Journals (Sweden)

, Affrilyno

2015-01-01

Full Text Available Teori Bigness yang digulirkan Rem Koolhaas merupakan teori yang menurut Rem Koolhaas mampu menghasilkan logika sendiri. Sekalipun teori ini dianggap sebagai bentuk yang berbeda dalam wacana arsitektur, namun keberadaannya memiliki pertumbuhan tersendiri. Ihwal teori ini berakar pada tatanan program Manhattanism yang ditulis Rem Koolhaas pada bukunya, Delirious New York (1978. Pada buku selanjutnya, S, M, L, XL (1995, Rem Koolhaas secara lebih terperinci memberikan implementasi aktual dari Manhattanism melalui berbagai proyek yang terealisasi maupun tidak terealisasi beserta tulisan-tulisan yang melingkupinya. Melalui karya tekstualnya, Rem Koolhaas telah mengembangkan pendekatan yang spesifik terhadap urbanisme dan arsitektur. Terkait problematika dalam arsitektur dan urbanisme yang menggulirkan permasalahan terhadap penolakan kompleksitas, kurangnya kontrol, oposisi, kontradiksi, dan skala yang besar, Rem Koolhaas justru merangkul kondisi ini dan menyatakannya sebagai titik awal untuk proyek-proyek mereka. Dalam konteks urban secara spesifik, Rem Koolhaas menyatakan permasalahan urban tidak lagi dapat dikendalikan dengan cara 'klasik' Modernisme. Permasalahan yang ada selanjutnya berfungsi sebagai sarana struktural untuk mengakomodasi permasalahan yang tidak dapat dikontrol. Isu-isu ini selanjutnya berperan sebagai instrumen baru dalam tatanan urbanisme dan arsitektur   Theory of Bigness as Koolhaas refers to it generates its own logic. Although the concept suffers from neglect in architectural discourse, it has prospered on its own. The program for Manhattanism has been established in 'Delirious New York' (1978. Furthermore, in the next book, S, M, L, XL (1995, Rem Koolhaas gives a record of the actual implementation of Manhattanism throughout the various (unrealized projects and texts. Through his books, Rem Koolhaas has developed a very specific approach towards urbanism and architecture. Related to the scope of the problems in

75 FR 20265 - Airworthiness Directives; Liberty Aerospace Incorporated Model XL-2 Airplanes

Science.gov (United States)

2010-04-19

... Office, 1701 Columbia Avenue, College Park, Georgia 30337; telephone: (404) 474-5524; facsimile: (404... Airworthiness Directives; Liberty Aerospace Incorporated Model XL-2 Airplanes AGENCY: Federal Aviation...-08- 05, which applies to certain Liberty Aerospace Incorporated Model XL-2 airplanes. AD 2009-08-05...

Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis

Directory of Open Access Journals (Sweden)

Yongxing Gong

2017-02-01

Full Text Available Mutation of the PARK2 gene can promote both Parkinson's Disease and cancer, yet the underlying mechanisms of how PARK2 controls cellular physiology is incompletely understood. Here, we show that the PARK2 tumor suppressor controls the apoptotic regulator BCL-XL and modulates programmed cell death. Analysis of approximately 10,000 tumor genomes uncovers a striking pattern of mutual exclusivity between PARK2 genetic loss and amplification of BCL2L1, implicating these genes in a common pathway. PARK2 directly binds to and ubiquitinates BCL-XL. Inactivation of PARK2 leads to aberrant accumulation of BCL-XL both in vitro and in vivo, and cancer-specific mutations in PARK2 abrogate the ability of the ubiquitin E3 ligase to target BCL-XL for degradation. Furthermore, PARK2 modulates mitochondrial depolarization and apoptosis in a BCL-XL-dependent manner. Thus, like genes at the nodal points of growth arrest pathways such as p53, the PARK2 tumor suppressor is able to exert its antiproliferative effects by regulating both cell cycle progression and programmed cell death.

Politics, proximity and the pipeline: Mapping public attitudes toward Keystone XL

International Nuclear Information System (INIS)

Gravelle, Timothy B.; Lachapelle, Erick

2015-01-01

The politics of oil pipelines have become increasingly salient in American politics in recent years. In particular, debates about economic benefits, energy security and environmental impact have been provoked by the proposed Keystone XL pipeline expansion intended to take bitumen from northern Alberta in Canada to refineries on the Gulf Coast in Texas. Drawing on data from recent surveys conducted by the Pew Research Center, this article asks a series of questions. What levels of support for (and opposition to) the pipeline exist among the American public? What are the roles of political factors (such as party identification and ideology), economic attitudes, environmental attitudes and proximity to the proposed pipeline route in shaping attitudes toward the pipeline? And how do political factors and proximity to the pipeline interact? We find that partisanship and ideology drive attitudes toward the Keystone XL pipeline, and that the effect of ideology is attenuated by proximity to the proposed route. The policy implications of these findings for energy infrastructure siting controversies are discussed. -- Highlights: •Americans are divided on the Keystone XL energy pipeline. •Attitudes toward Keystone XL are driven by political party identification and ideology. •Attitudes toward the pipeline are also shaped by attitudes toward the economy and global warming. •The effect of proximity on attitudes toward Keystone XL is non-linear. •Spatial proximity to the pipeline attenuates the effect of ideology

Using Networks For Changing Innovation Strategy: The Case of IBM

OpenAIRE

Dittrich, Koen; Duysters, Geert; Man, Ard-Pieter

2004-01-01

textabstractLarge-scale strategic change projects in companies may be supported by using alliance networks. This paper shows that IBM’s change from an exploitation strategy towards an exploration strategy required a radically different network strategy as well. By entering into more non-equity alliances, involving new partners in the network and loosening the ties with existing partners, IBM supported its transformation from a hardware manufacturing company to a global service provider and so...

Miks IBM müüb kroonijuveeli? / Valdo Randpere

Index Scriptorium Estoniae

Randpere, Valdo, 1958-

2004-01-01

Kuna konkurents on väga tihe, siis IBM loobub väikese marginaaliga personaalarvutite ärist ning keskendub serveritele ja keerukatele ärilahendustele. Lisa: IBM müüb personaalarvutite divisjoni hiinlastele

Uporaba orodja poslovne inteligence IBM Watson za predvidevanje prodaje

OpenAIRE

Stojić, Igor

2016-01-01

Diplomska naloga obravnava uporabo orodja IBM Watson in njegovo poslovno vrednost, ki jo ima v okviru oblikovanja napovedi prihodnje prodaje produktov. V teoretičnem delu podrobneje opredeljuje napovedovanje in smoter le-tega. V okviru empiričnega dela pa je bila izvedena primerjava uporabe ERP sistemov SAP in IBM Watson, pri čemer je bil dosledno prikazan postopek oblikovanja napovedi, tako s SAP kot tudi z IBM Watson, s slednjim pa tudi identificiran parameter, ki vpliva na prodajo nekateri...

CC-3 CAMAC crate controller for IBM PC

International Nuclear Information System (INIS)

Khare, A.N.; Ghodgaonkar, M.D.; Bairi, B.R.

1991-01-01

The specifications and implementation details of CAMAC Crate Controller CC-3 for IBM-PC compatible as a host computer, having capability to transfer high speed data with direct memory access (DMA) scheme and logic to execute CAMAC cycles directly from the crate controller, to implement the block algorithms specified in ANSI/IEEE Std. 683-1976 (Reaff-1981) are described. The maximum data transfer rate measured with 8 bit interface of PC-AT is 240K byte per second. This work is carried out under Seventh Five Year Plan Project on Modernisation of reactor Control Instrumentation and Development of CAMAC and Fastbus Instrumentation. (author). 9 refs., 5 figs., 4 appendixes

Implementation of NASTRAN on the IBM/370 CMS operating system

Science.gov (United States)

Britten, S. S.; Schumacker, B.

1980-01-01

The NASA Structural Analysis (NASTRAN) computer program is operational on the IBM 360/370 series computers. While execution of NASTRAN has been described and implemented under the virtual storage operating systems of the IBM 370 models, the IBM 370/168 computer can also operate in a time-sharing mode under the virtual machine operating system using the Conversational Monitor System (CMS) subset. The changes required to make NASTRAN operational under the CMS operating system are described.

INIS information retrieval based on IBM's IRMS

International Nuclear Information System (INIS)

Gadjokov, V.; Schmid, H.; Del Bigio, G.

1975-01-01

An information retrieval system for the INIS data base is described. It allows for batch processing on an IBM/360 or /370 computer operated under OS or VS. The program package consists basically of IBM's IRMS system which was converted from DOS to OS and adapted for INIS requirements. Sections 1-9 present the system from the user's point of view, deliberately omitting all the programming details. Program descriptions with data set definitions and file formats are given in sections 10-12. (author)

On IBM's Millennial Puzzle

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 10. On IBM's Millennial Puzzle. A Sarangarajan. Classroom Volume 5 Issue 10 October 2000 pp 81-89. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/005/10/0081-0089. Author Affiliations.

Flight Test Results for the F-16XL With a Digital Flight Control System

Science.gov (United States)

Stachowiak, Susan J.; Bosworth, John T.

2004-01-01

In the early 1980s, two F-16 airplanes were modified to extend the fuselage length and incorporate a large area delta wing planform. These two airplanes, designated the F-16XL, were designed by the General Dynamics Corporation (now Lockheed Martin Tactical Aircraft Systems) (Fort Worth, Texas) and were prototypes for a derivative fighter evaluation program conducted by the United States Air Force. Although the concept was never put into production, the F-16XL prototypes provided a unique planform for testing concepts in support of future high-speed supersonic transport aircraft. To extend the capabilities of this testbed vehicle the F-16XL ship 1 aircraft was upgraded with a digital flight control system. The added flexibility of a digital flight control system increases the versatility of this airplane as a testbed for aerodynamic research and investigation of advanced technologies. This report presents the handling qualities flight test results covering the envelope expansion of the F-16XL with the digital flight control system.

Characterization of steel 70XL used in the manufacture of balls for the clinker's milling

Directory of Open Access Journals (Sweden)

Eider Gresesqui-Lobaina

2017-10-01

Full Text Available The present article deals with the wear of the balls used for the grinding of the clinker in the processes of obtaining cement. Three specimens of different steel were made: one of steel AISI 4140, with which balls are forged for the milling process; another 70XL steel (70 XL with normalized, tempered and tempered thermal treatments; and the third, of equal material that the second but without treatment. For the metallographic observation the samples were made with dimensions of 10 mm in diameter and 8 mm in thickness, revealing for AISI 4140 steel a structure of martensitic type with some presence of acicular ferrite. For the 70XL steel without heat treatment the presence of ferrite and cementite was observed, while the steel 70XL with heat treatment showed in the limits of free cementite grain in a pearly matrix, which resulted in a higher hardness (up to HRC 59 , 8 and lower gravimetric wear compared to other materials. Therefore it is recommended as the most suitable for the manufacture of balls for grinding minerals 70XL steel with heat treatment.

PREVAIL: IBM's e-beam technology for next generation lithography

Science.gov (United States)

Pfeiffer, Hans C.

2000-07-01

PREVAIL - Projection Reduction Exposure with Variable Axis Immersion Lenses represents the high throughput e-beam projection approach to NGL which IBM is pursuing in cooperation with Nikon Corporation as alliance partner. This paper discusses the challenges and accomplishments of the PREVAIL project. The supreme challenge facing all e-beam lithography approaches has been and still is throughput. Since the throughput of e-beam projection systems is severely limited by the available optical field size, the key to success is the ability to overcome this limitation. The PREVAIL technique overcomes field-limiting off-axis aberrations through the use of variable axis lenses, which electronically shift the optical axis simultaneously with the deflected beam so that the beam effectively remains on axis. The resist images obtained with the Proof-of-Concept (POC) system demonstrate that PREVAIL effectively eliminates off- axis aberrations affecting both resolution and placement accuracy of pixels. As part of the POC system a high emittance gun has been developed to provide uniform illumination of the patterned subfield and to fill the large numerical aperture projection optics designed to significantly reduce beam blur caused by Coulomb interaction.

IBM, Elsevier Science, and academic freedom.

Science.gov (United States)

Bailar, John C; Cicolella, Andre; Harrison, Robert; LaDou, Joseph; Levy, Barry S; Rohm, Timothy; Teitelbaum, Daniel T; Wang, Yung-Der; Watterson, Andrew; Yoshida, Fumikazu

2007-01-01

Elsevier Science refused to publish a study of IBM workers that IBM sought to keep from public view. Occupational and environmental health (OEH) suffers from the absence of a level playing field on which science can thrive. Industry pays for a substantial portion of OEH research. Studies done by private consulting firms or academic institutions may be published if the results suit the sponsoring companies, or they may be censored. OEH journals often reflect the dominance of industry influence on research in the papers they publish, sometimes withdrawing or modifying papers in line with industry and advertising agendas. Although such practices are widely recognized, no fundamental change is supported by government and industry or by professional organizations.

Collective states of even Xe isotopes in IBM+MQRPA

Directory of Open Access Journals (Sweden)

Efimov A. D.

2016-01-01

Full Text Available A modification of the Quasiparticle Random Phase Approximation (QRPA with small ground state correlations is suggested. The lowest energy phonon is used as the image of d-boson of the Interacting Boson Model 1 (IBM1 and applied to microscopical calculations of the IBM1 parameters. Results are compared with experimental data for Xe isotopes.

Steady-state pharmacokinetics of fluvastatin in healthy subjects following a new extended release fluvastatin tablet, Lescol XL.

Science.gov (United States)

Barilla, Denise; Prasad, Pratapa; Hubert, Martine; Gumbhir-Shah, Kavita

2004-03-01

This was an open-label, randomized, three-period, three-treatment, multiple dose, crossover study in 12 healthy male and female subjects. This study evaluated single dose and steady-state pharmacokinetics of fluvastatin following single and multiple dose administrations of a new extended release fluvastatin 8 h matrix tablet, Lescol XL 80 mg and 160 mg doses once a day. The study also included a twice a day administration of an immediate release (IR) form of fluvastatin capsule, Lescol, for comparative purposes. All doses were administered for 7 days. The safety and tolerability were also assessed. The pharmacokinetics of fluvastatin were evaluated on days 1 and 7 following each treatment. Fluvastatin systemic exposure was 50% less when administered as Lescol XL 80 mg qd compared with Lescol IR 40 mg bid. Conversely, fluvastatin systemic exposure was 22% higher when administered as Lescol XL 160 mg qd compared with Lescol IR 40 mg bid. Single doses of Lescol XL 80 mg and 160 mg were dose proportional but, deviation (30%) from dose proportionality was observed for the Lescol XL 160 mg at steady-state. There appeared to be moderate (20%-40%) accumulation of serum fluvastatin maximal concentrations and exposure after multiple doses of Lescol XL tablets. Both Lescol XL 80 mg and 160 mg showed delayed absorption and longer apparent elimination half-life compared with fluvastatin IR capsule. Single and multiple doses of fluvastatin were generally well tolerated in this healthy volunteer population. Adverse event profiles were consistent with the published safety profile of the marketed formulations. Aside from one incidence of creatine phosphokinase (CPK) elevation (following Lescol XL 160 mg qd treatment), there were no safety concerns with any of the treatments when administered acutely (7 days). Copyright 2004 John Wiley & Sons, Ltd.

Data Discovery with IBM Watson

Science.gov (United States)

Fessler, J.

2016-12-01

BM Watson is a cognitive computing system that uses machine learning, statistical analysis, and natural language processing to find and understand the clues in questions posed to it. Watson was made famous when it bested two champions on TV's Jeopardy! show. Since then, Watson has evolved into a platform of cognitive services that can be trained on very granular fields up study. Watson is being used to support a number of subject domains, such as cancer research, public safety, engineering, and the intelligence community. IBM will be providing a presentation and demonstration on the Watson technology and will discuss its capabilities including Natural Language Processing, text analytics and enterprise search, as well as cognitive computing with deep Q&A. The team will also be giving examples of how IBM Watson technology is being used to support real-world problems across a number of public sector agencies

IBM WebSphere Application Server 80 Administration Guide

CERN Document Server

Robinson, Steve

2011-01-01

IBM WebSphere Application Server 8.0 Administration Guide is a highly practical, example-driven tutorial. You will be introduced to WebSphere Application Server 8.0, and guided through configuration, deployment, and tuning for optimum performance. If you are an administrator who wants to get up and running with IBM WebSphere Application Server 8.0, then this book is not to be missed. Experience with WebSphere and Java would be an advantage, but is not essential.

The IBM i Programmer's Guide to PHP

CERN Document Server

Olen, Jeff

2012-01-01

This is the first book to comprehensively address PHP and how it can-and should-be deployed on the IBM i. With this IBM i-specific point of view, the authors examine how to transfer skills from a green screen environment to the Web, become intimately familiar with PHP's commonly used features, and help start down the road of highly interactive Web-based application development. For decades, the green screen has been the ubiquitous interface into an organization's data. But with the advent of HTML, the Internet, and the browser, combined with the end user's existing familiarity with the Web,

Flexible input, dazzling output with IBM i

CERN Document Server

Victória-Pereira, Rafael

2014-01-01

Link your IBM i system to the modern business server world! This book presents easier and more flexible ways to get data into your IBM i system, along with rather surprising methods to export and present the vital business data it contains. You'll learn how to automate file transfers, seamlessly connect PC applications with your RPG programs, and much more. Input operations will become more flexible and user-proof, with self-correcting import processes and direct file transfers that require a minimum of user intervention. Also learn novel ways to present information: your DB2 data will look gr

New Generation General Purpose Computer (GPC) compact IBM unit

Science.gov (United States)

1991-01-01

New Generation General Purpose Computer (GPC) compact IBM unit replaces a two-unit earlier generation computer. The new IBM unit is documented in table top views alone (S91-26867, S91-26868), with the onboard equipment it supports including the flight deck CRT screen and keypad (S91-26866), and next to the two earlier versions it replaces (S91-26869).

IbM PENYUSUNAN PENILAIAN AUTENTIK BAGI GURU SEKOLAH DI PONPES DARUL FIKRI BAWEN

Directory of Open Access Journals (Sweden)

Joko Siswanto

2015-09-01

Full Text Available Abstract Low motivation of teachers in implementing authentic assessment becomes the basis for IbM team to carry out extension activities. Authentic assessment has actually been around a long time, but this issue arose when the curriculum was launched in 2013. During this time, most of the teachers at school in the field only make an assessment test course, not many people touched assessment tests that are written. Through activities of IbM Authentic Assessment Preparation Training for Teachers of Pesantren Darul Fikri Bawen, participants are expected to conduct a written assessment, performance assessment, product assessment projects, portfolio assessment, and manage the mark using computer-based process. Prior to socialization, teachers must first take pretest and post test. Pre test shows an average score of 89.65 while the average of post-test scores shows 97.6. During the activities, the participants felt helped and gave a positive response to organized similar activities. Keywords: Preparation, Assessment Authentic, Darul Fikri Boarding School Teacher

Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization.

Science.gov (United States)

Shah, O Jameel; Lin, Xiaoyu; Li, Leiming; Huang, Xiaoli; Li, Junling; Anderson, Mark G; Tang, Hua; Rodriguez, Luis E; Warder, Scott E; McLoughlin, Shaun; Chen, Jun; Palma, Joann; Glaser, Keith B; Donawho, Cherrie K; Fesik, Stephen W; Shen, Yu

2010-07-13

Aurora kinase B inhibitors induce apoptosis secondary to polyploidization and have entered clinical trials as an emerging class of neocytotoxic chemotherapeutics. We demonstrate here that polyploidization neutralizes Mcl-1 function, rendering cancer cells exquisitely dependent on Bcl-XL/-2. This "addiction" can be exploited therapeutically by combining aurora kinase inhibitors and the orally bioavailable BH3 mimetic, ABT-263, which inhibits Bcl-XL, Bcl-2, and Bcl-w. The combination of ABT-263 with aurora B inhibitors produces a synergistic loss of viability in a range of cell lines of divergent tumor origin and exhibits more sustained tumor growth inhibition in vivo compared with aurora B inhibitor monotherapy. These data demonstrate that Bcl-XL/-2 is necessary to support viability during polyploidization in a variety of tumor models and represents a druggable molecular vulnerability with potential therapeutic utility.

George E. Pake Prize Lecture: Physical Sciences Research at IBM: Still at the Cutting Edge

Science.gov (United States)

Theis, Thomas

2015-03-01

The information technology revolution is in its ``build out'' phase. The foundational scientific insights and hardware inventions are now many decades old. The microelectronics industry is maturing. An increasing fraction of the total research investment is in software and services, as applications of information technology transform every business and every sector of the public and private economy. Yet IBM Research continues to make substantial investments in hardware technology and the underlying physical sciences. While some of this investment is aimed at extending the established transistor technology, an increasing fraction is aimed at longer-term and possibly disruptive research - new devices for computing, such as tunneling field-effect transistors and nanophotonic circuits, and new architectures, such as neurosynaptic systems and quantum computing. This research investment is a bet that the old foundations of information technology are ripe for reinvention. After all, today's information technology devices and systems operate far from any fundamental limits on speed and energy efficiency. But how can IBM make risky long-term research investments in an era of global competition, with financial markets focused on the short term? One important answer is partnerships. Since its early days, IBM Research has pursued innovation in information technology and innovation in the ways it conducts the business of research. By continuously evolving new models for research and development partnerships, it has extended its global reach, increased its impact on IBM's customers, and expanded the breadth and depth of its research project portfolio. Research in the physical sciences has often led the way. Currently on assignment to the Semiconductor Research Corporation.

IBM KELOMPOK USAHA SOUVENIR SABLON DIGITAL

Directory of Open Access Journals (Sweden)

Maria krisnawati

2015-12-01

Full Text Available Kegiatan IbM dilaksanakan pada kelompok souvenir sablon digital di Desa Sidodadi dan Karanglo Kecamatan Tawangnangu Kabupaten Karanganyar. Kegiatan ini bertujuan untuk: 1 meningkatkan motivasi wirausaha mitra; 2 meningkatkan pemahaman mitra tentang perencanaan bisnis dan manajemen usaha; 3 meningkatkan kemampuan SDM dalam teknik produksi dan pemasaran; serta 4 mengembangkan jejaring kewirausahaan pemuda untuk menopang pengembangan ekonomi kreatif. Target yang akan dicapai melalui IbM adalah pada aspek produksi dan manajemen. Aspek produksi, yaitu meningkatnya teknologi produksi pembuatan souvenir, meningkatnya kemampuan dalam bidang desain melalui program corel draw dan Adobe photoshop serta pemantapan prosedur produksi dengan memperhatikan kesehatan dan keselamatan kerja. Aspek manajemen, yaitu pada manajemen keuangan, mengadakan pengelolaaan keuangan yang baik dengan pembukuan yang teratur, melalui manajemen pemasaran menghasilkan bentuk-bentuk promosi melalui berbagai media, perluasan jaringan pasar dan mempermudah akses konsumen memesan produk. Melalui manajemen SDM dapat meningkatkan kemampuan SDM dengan pelatihan, pemberian motivasi wirausaha dan pemberdayaan diri.Kegiatan IbM dilaksanakan melalui tahapan 1 Tahap Persiapan; 2 Tahap Assesment; 3 Tahap Perencanaan Program atau Kegiatan; 4 Tahap Pemformulasian Rencana Aksi; 5 Tahap Pelaksanaan (Implementasi Program atau Kegiatan; serta 6 Tahap Evaluasi. Diharapkan melalui tahapan yang akan dilaksanakan dapat membantu menyelesaikan permasalahan dan memenuhi kebutuhan mitra.Kata kunci : IbM, pelatihan, pembinaan, pendampingan, souvenir, sablon digital.

Applications Performance Under MPL and MPI on NAS IBM SP2

Science.gov (United States)

Saini, Subhash; Simon, Horst D.; Lasinski, T. A. (Technical Monitor)

1994-01-01

On July 5, 1994, an IBM Scalable POWER parallel System (IBM SP2) with 64 nodes, was installed at the Numerical Aerodynamic Simulation (NAS) Facility Each node of NAS IBM SP2 is a "wide node" consisting of a RISC 6000/590 workstation module with a clock of 66.5 MHz which can perform four floating point operations per clock with a peak performance of 266 Mflop/s. By the end of 1994, 64 nodes of IBM SP2 will be upgraded to 160 nodes with a peak performance of 42.5 Gflop/s. An overview of the IBM SP2 hardware is presented. The basic understanding of architectural details of RS 6000/590 will help application scientists the porting, optimizing, and tuning of codes from other machines such as the CRAY C90 and the Paragon to the NAS SP2. Optimization techniques such as quad-word loading, effective utilization of two floating point units, and data cache optimization of RS 6000/590 is illustrated, with examples giving performance gains at each optimization step. The conversion of codes using Intel's message passing library NX to codes using native Message Passing Library (MPL) and the Message Passing Interface (NMI) library available on the IBM SP2 is illustrated. In particular, we will present the performance of Fast Fourier Transform (FFT) kernel from NAS Parallel Benchmarks (NPB) under MPL and MPI. We have also optimized some of Fortran BLAS 2 and BLAS 3 routines, e.g., the optimized Fortran DAXPY runs at 175 Mflop/s and optimized Fortran DGEMM runs at 230 Mflop/s per node. The performance of the NPB (Class B) on the IBM SP2 is compared with the CRAY C90, Intel Paragon, TMC CM-5E, and the CRAY T3D.

Training in the Workplace: An IBM Case Study. Contractor Report.

Science.gov (United States)

Grubb, Ralph E.

International Business Machines Corporation's (IBM) efforts to develop a corporate culture are associated with its founder, Thomas J. Watson, Sr. From the start of his association with the company in 1914, the importance of education was stressed. The expansion of the education and training organization paralleled IBM's 75-year growth. In January…

Analyzing Social Media Networks with NodeXL Insights from a Connected World

CERN Document Server

Hansen, Derek; Smith, Marc A

2010-01-01

Businesses, entrepreneurs, individuals, and government agencies alike are looking to social network analysis (SNA) tools for insight into trends, connections, and fluctuations in social media. Microsoft's NodeXL is a free, open-source SNA plug-in for use with Excel. It provides instant graphical representation of relationships of complex networked data. But it goes further than other SNA tools -- NodeXL was developed by a multidisciplinary team of experts that bring together information studies, computer science, sociology, human-computer interaction, and over 20 years of visual analytic theor

Improvement of exercise capacity and left ventricular diastolic function with metoprolol XL after acute myocardial infarction

DEFF Research Database (Denmark)

Poulsen, S H; Jensen, S E; Egstrup, K

2000-01-01

dysfunction after acute myocardial infarction were given metoprolol XL (n = 29) or placebo (n = 30). The effects of metoprolol XL on exercise capacity in relation to effects on LV diastolic filling were studied. Two-dimensional Doppler echocardiography and maximal symptom limited bicycle test were performed...

F-16XL ship #1 (#849) during first flight of the Digital Flight Control System (DFCS)

Science.gov (United States)

1997-01-01

After completing its first flight with the Digital Flight Control System on December 16, 1997, the F-16XL #1 aircraft began a series of envelope expansion flights. On January 27 and 29, 1998, it successfully completed structural clearance tests, as well as most of the load testing Only flights at Mach 1.05 at 10,000 feet, Mach 1.1 at 15,000 feet, and Mach 1.2 at 20,000 feet remained. During the next flight, on February 4, an instrumentation problem cut short the planned envelope expansion tests. After the problem was corrected, the F-16XL returned to flight status, and on February 18 and 20, flight control and evaluation flights were made. Two more research flights were planned for the following week, but another problem appeared. During the ground start up, project personnel noticed that the leading edge flap moved without being commanded. The Digital Flight Control Computer was sent to the Lockheed-Martin facility at Fort Worth, where the problem was traced to a defective chip in the computer. After it was replaced, the F-16XL #1 flew a highly successful flight controls and handling qualities evaluation flight on March 26, clearing the way for the final tests. The final limited loads expansion flight occurred on March 31, and was fully successful. As a result, the on-site Lockheed-Martin loads engineer cleared the aircraft to Mach 1.8. The remaining two handling qualities and flight control evaluation flights were both made on April 3, 1998. These three flights concluded the flight test portion of the DFCS upgrade.

Training IBM Watson using Automatically Generated Question-Answer Pairs

OpenAIRE

Lee, Jangho; Kim, Gyuwan; Yoo, Jaeyoon; Jung, Changwoo; Kim, Minseok; Yoon, Sungroh

2016-01-01

IBM Watson is a cognitive computing system capable of question answering in natural languages. It is believed that IBM Watson can understand large corpora and answer relevant questions more effectively than any other question-answering system currently available. To unleash the full power of Watson, however, we need to train its instance with a large number of well-prepared question-answer pairs. Obviously, manually generating such pairs in a large quantity is prohibitively time consuming and...

IBM SPSS Modeler cookbook

CERN Document Server

McCormick, Keith

2013-01-01

This is a practical cookbook with intermediate-advanced recipes for SPSS Modeler data analysts. It is loaded with step-by-step examples explaining the process followed by the experts.If you have had some hands-on experience with IBM SPSS Modeler and now want to go deeper and take more control over your data mining process, this is the guide for you. It is ideal for practitioners who want to break into advanced analytics.

Epithelium-on photorefractive intrastromal cross-linking (PiXL for reduction of low myopia

Directory of Open Access Journals (Sweden)

Lim WK

2017-06-01

Full Text Available Wee Kiak Lim,1,2 Zhi Da Soh,1 Harold Kah Yen Choi,1 Julian Thiam Siew Theng1,3 1Eagle Eye Centre, Mount Alvernia Hospital, 2Department of Ophthalmology, Tan Tock Seng Hospital, 3Department of Ophthalmology, Khoo Teck Puat Hospital, Singapore Purpose: To report the 9–12-month outcomes of a novel procedure for reduction of low myopia through epithelium-on photorefractive intrastromal cross-linking (PiXL with customized control of topographic distribution of ultraviolet (UV-fluence. Method: Myopic patients with normal (non-ectatic corneas underwent the PiXL procedure for reduction of low myopia. PiXL treatments were delivered through selective application of UVA light based on the refractive error of each patient. Clinical evaluation included safety (corrected distance visual acuity, endothelial cell count, central corneal thickness, anterior ocular health and efficacy (uncorrected distance visual acuity, manifest refraction, K-mean examinations. In addition, a patient satisfaction survey was conducted at 9 months post-procedure to evaluate patients’ subjective experience with the procedure. Results: Fourteen myopic eyes (mean manifest refraction spherical equivalent –1.62±0.6D; range –0.75 to –2.65D of 8 subjects (mean age 30 years old; range 24–51 years old were enrolled in the study. At 12 months post-procedure, a mean manifest refraction spherical equivalent reduction of 0.72±0.43D (P<0.001 was observed, with a corresponding gain in uncorrected visual acuity of 0.25 logMAR and mean K-mean flattening of 0.47±0.46D. All patients achieved best corrected visual acuity of 20/20 or better from 1 month onward. There were no cases of ocular infection or secondary changes to the crystalline lens and retina due to UV exposure, while transient corneal haze subsided gradually. Conclusion: The epithelium-on PiXL procedure was safe and effective in reducing myopic refractive error in this study with up to 12 months follow-up. Early results of

Characterization of X-linked Hypohidrotic Ectodermal Dysplasia (XL-HED) Hair and Sweat Gland Phenotypes Using Phototrichogram Analysis and Live Confocal Imaging

Science.gov (United States)

Jones, Kyle B.; Goodwin, Alice F.; Landan, Maya; Seidel, Kerstin; Tran, Dong-Kha; Hogue, Jacob; Chavez, Miquella; Fete, Mary; Yu, Wenli; Hussein, Tarek; Johnson, Ramsey; Huttner, Kenneth; Jheon, Andrew H.; Klein, Ophir D.

2015-01-01

Hypohidrotic ectodermal dysplasia (HED) is the most common type of ectodermal dysplasia (ED), which encompasses a large group of syndromes that share several phenotypic features such as missing or malformed ectodermal structures, including skin, hair, sweat glands, and teeth. X-linked hypohidrotic ectodermal dysplasia (XL-HED) is associated with mutations in ectodysplasin (EDA1). Hypohidrosis due to hypoplastic sweat glands and thin, sparse hair are phenotypic features that significantly affect the daily lives of XL-HED individuals and therefore require systematic analysis. We sought to determine the quality of life of individuals with XL-HED and to quantify sweat duct and hair phenotypes using confocal imaging, pilocarpine iontophoresis, and phototrichogram analysis. Using these highly sensitive and non-invasive techniques, we demonstrated that 11/12 XL-HED individuals presented with a complete absence of sweat ducts and that none produced sweat. We determined that the thin hair phenotype observed in XL-HED was due to multiple factors, such as fewer terminal hairs with decreased thickness and slower growth rate, as well as fewer follicular units and fewer hairs per unit. The precise characterization of XL-HED phenotypes using sensitive and non-invasive techniques presented in our study will improve upon larger genotype-phenotype studies and in the assessment of future therapies in XL-HED. PMID:23687000

CDF-XL: computing cumulative distribution functions of reaction time data in Excel.

Science.gov (United States)

Houghton, George; Grange, James A

2011-12-01

In experimental psychology, central tendencies of reaction time (RT) distributions are used to compare different experimental conditions. This emphasis on the central tendency ignores additional information that may be derived from the RT distribution itself. One method for analysing RT distributions is to construct cumulative distribution frequency plots (CDFs; Ratcliff, Psychological Bulletin 86:446-461, 1979). However, this method is difficult to implement in widely available software, severely restricting its use. In this report, we present an Excel-based program, CDF-XL, for constructing and analysing CDFs, with the aim of making such techniques more readily accessible to researchers, including students (CDF-XL can be downloaded free of charge from the Psychonomic Society's online archive). CDF-XL functions as an Excel workbook and starts from the raw experimental data, organised into three columns (Subject, Condition, and RT) on an Input Data worksheet (a point-and-click utility is provided for achieving this format from a broader data set). No further preprocessing or sorting of the data is required. With one click of a button, CDF-XL will generate two forms of cumulative analysis: (1) "standard" CDFs, based on percentiles of participant RT distributions (by condition), and (2) a related analysis employing the participant means of rank-ordered RT bins. Both analyses involve partitioning the data in similar ways, but the first uses a "median"-type measure at the participant level, while the latter uses the mean. The results are presented in three formats: (i) by participants, suitable for entry into further statistical analysis; (ii) grand means by condition; and (iii) completed CDF plots in Excel charts.

[Comparison of the M and XL FibroScan(®) probes to estimate liver stiffness by transient elastography].

Science.gov (United States)

Herrero, José Ignacio; Iñarrairaegui, Mercedes; D'Avola, Delia; Sangro, Bruno; Prieto, Jesús; Quiroga, Jorge

2014-04-01

The FibroScan(®) XL probe has been specifically designed for obese patients to measure liver stiffness by transient elastography, but it has not been well tested in non-obese patients. The aim of this study was to compare the M and XL FibroScan(®) probes in a series of unselected obese (body mass index above 30 kg/m(2)) and non-obese patients with chronic liver disease. Two hundred and fifty-four patients underwent a transient elastography examination with both the M and XL probes. The results obtained with the two probes were compared in the whole series and in obese (n=82) and non-obese (n=167) patients separately. The reliability of the examinations was assessed using the criteria defined by Castéra et al. The proportion of reliable exams was significantly higher when the XL probe was used (83% versus 73%; P=.001). This significance was maintained in the group of obese patients (82% versus 55%; P<.001), but not in the non-obese patients (84% versus 83%). Despite a high correlation between the stiffness values obtained with the two probes (R=.897; P<.001), and a high concordance in the estimation of fibrosis obtained with the two probes (Cronbach's alpha value: 0.932), the liver stiffness values obtained with the XL probe were significantly lower than those obtained with the M probe, both in the whole series (9.5 ± 9.1 kPa versus 11.3 ± 12.6 kPa; P<0.001) and in the obese and non-obese groups. In conclusion, transient elastography with the XL probe allows a higher proportion of reliable examinations in obese patients but not in non-obese patients. Stiffness values were lower with the XL probe than with the M probe. Copyright © 2013 Elsevier España, S.L. and AEEH y AEG. All rights reserved.

PC-Link historical data base system MODCOMP/IBM at link for neutral particle beam operation

International Nuclear Information System (INIS)

Thurgood, P.

1989-01-01

PC-Link is a combination of hardware and software that connects an IBM PC/AT to a MODCOMP minicomputer. It is designed as an aid to the Neutral Beam operations coordinator during injection into the DIII-D tokamak project. An IBM PC/AT is linked to 4 MODCOMP realtime acquisition systems, each of which controls 2 neutral particle beam sources. At various points in the shot sequence, data is sent to the IBM PC/AT. This data can then be integrated with the data from the other sources into tables or graphics displays for use by the Beam Coordinator. In this way, the coordinator gets realtime feedback on the relative settings and performance of the sources and can observe trends within a particular source at one location. The PC-Link is used for observing relative timing information and for post shot historical archiving. The concept of the PC-Link was originally proposed several years ago. In April 1988, in-house implementation of the link software was begun. The PC-Link receives approximately 2 Kbytes of data per source per shot. This data is converted from MODCOMP format to IBM PC format and archived to disk. The last 280 shots per source are stored to disk to observe trends. The data can be displayed in a number of formats depending upon the situation. For example, prior to a shot, the beam MODCOMPs are sent timing information from the DIII-D tokamak control system. This data is echoed on the PC in a graphical representation displaying all 8 sources. At the end of the shot, the actual running times are displayed along with the requested settings. Any subset of the Historical data may be displayed either graphically or in tables for realtime comparisons between sources. 4 figs

The IBM neutrino-mass experiment

International Nuclear Information System (INIS)

Clark, G.J.; Frisch, M.A.; Chaudhari, P.; Bregman, M.F.

1985-01-01

IBM is undertaking an experiment to measure the electron anti-neutrino mass. A high precision measurement of the tritium Β-decay spectrum near the end point is used to infer the neutrino mass. Electron energies are measured using a large spherical retarding grid analyzer. We are placing particular emphasis on understanding the complications introduced by solid state effects in the source

The IBM neutrino-mass experiment

International Nuclear Information System (INIS)

Clark, G.J.; Frisch, M.A.; Chaudhari, P.; Bregman, M.F.

1985-01-01

IBM is undertaking an experiment to measure the electron anti-neutrino mass. A high precision measurement of the tritium β-decay spectrum near the end point is used to infer the neutrino mass. Electron energies are measured using a large spherical retarding grid analyzer. They are placing particular emphasis on understanding the complications introduced by solid state effects in the source

Making IBM's Computer, Watson, Human

Science.gov (United States)

Rachlin, Howard

2012-01-01

This essay uses the recent victory of an IBM computer (Watson) in the TV game, "Jeopardy," to speculate on the abilities Watson would need, in addition to those it has, to be human. The essay's basic premise is that to be human is to behave as humans behave and to function in society as humans function. Alternatives to this premise are considered…

IBM Brazil: and environmental modern view

Energy Technology Data Exchange (ETDEWEB)

Cremonesi, Valter [IBM Brasil, Industria, Maquinas e Servicos Ltda., Rio de Janeiro, Rj (Brazil)

1994-12-31

Information of practical experiences on Environmental Affairs at IBM Brazil plant and branch offices is presented, with a modern view of the mission, resources, support, waste management, monitoring programs, recycling, energy conservation, partners programs, nature preservation 2rograms, recognitions and image. (author). 4 figs., 2 tabs.

IBM Brazil: and environmental modern view

Energy Technology Data Exchange (ETDEWEB)

Cremonesi, Valter [IBM Brasil, Industria, Maquinas e Servicos Ltda., Rio de Janeiro, Rj (Brazil)

1993-12-31

Information of practical experiences on Environmental Affairs at IBM Brazil plant and branch offices is presented, with a modern view of the mission, resources, support, waste management, monitoring programs, recycling, energy conservation, partners programs, nature preservation 2rograms, recognitions and image. (author). 4 figs., 2 tabs.

IBM KELOMPOK USAHA SOUVENIR SABLON DIGITAL

Directory of Open Access Journals (Sweden)

Maria Krisnawati

2015-02-01

Full Text Available Targets to be achieved through IbM is on aspects of production and management. Aspects of the production which increased the production technology of making souvenirs, increasing capacity in the field of design through the program Corel Draw and Adobe Photoshop as well as consolidation of production procedures with due regard to health and safety work management. Management aspects namely on financial management, financial management hold good with regular bookkeeping, through marketing management produces forms of promotion through various media. Market network expansion and facilitate consumer access to order products.Through HR management can improve the training of human resources, the provision of entrepreneurial motivation and self empowerment. IbM implemented through phases 1 Preparation ; 2 Stage Assessment ; 3 The Plan or Program Activity; 4 Phase Action Plan ; 5 Implementation Phase or activity ; and 6 Evaluation Phase . It is expected to be implemented through the stages can help solve problems and realize the needs of partners.

The web server of IBM's Bioinformatics and Pattern Discovery group.

Science.gov (United States)

Huynh, Tien; Rigoutsos, Isidore; Parida, Laxmi; Platt, Daniel; Shibuya, Tetsuo

2003-07-01

We herein present and discuss the services and content which are available on the web server of IBM's Bioinformatics and Pattern Discovery group. The server is operational around the clock and provides access to a variety of methods that have been published by the group's members and collaborators. The available tools correspond to applications ranging from the discovery of patterns in streams of events and the computation of multiple sequence alignments, to the discovery of genes in nucleic acid sequences and the interactive annotation of amino acid sequences. Additionally, annotations for more than 70 archaeal, bacterial, eukaryotic and viral genomes are available on-line and can be searched interactively. The tools and code bundles can be accessed beginning at http://cbcsrv.watson.ibm.com/Tspd.html whereas the genomics annotations are available at http://cbcsrv.watson.ibm.com/Annotations/.

Dynamics of Innovation at IBM, 1945-1953

DEFF Research Database (Denmark)

Heide, Lars

The paper explores the use of sociotechnical network and sensemaking theory in early early innovation of computer technology at IBM to improve the understanding of the dynamics in innovation processes through the study of individuals’ contributions in a large company. It complements Actor Network...... Theory by Karl E. Weick’s sensemaking and studies innovation processes through narratives. This approach supplements the literature’s institutional focus and provides more focus on the technology’s use and limitations on innovations. In the mid-1940s, IBM was reluctant to engage in computer innovation......, because its sales organization and top-management saw little computer business. They subscribed to the established corporate innovation narrative of incremental improvements of the company’s many single punched-card machines, which contrasted the challenges of the revolutionary shift to computers. However...

Pengaruh e-CRM dan Service Quality terhadap Customer Satisfaction dan Dampaknya terhadap Customer Loyalty pada PT XL

Directory of Open Access Journals (Sweden)

Marshellina Marshellina

2013-11-01

Full Text Available This study aims to look at the influence and how much the influence of e-CRM (X1 and Quality of Service (X2 for Customer Satisfaction (Y that impact on Customer Loyalty (Z at PT XL. Data collection techniques were with questionnaires, the number of population in this study was approximately three millionrespondents, ie customers who use the product XL in West Jakarta, because the area most widely uses XL provider. Total sample was 100 respondents and the technique used was simple random sampling. The method used in this study was Pearson correlation and path analysis. Based on the results of data analysis, structural equation is Y = 0.310 + 0.330 X1 + X2 0.874 and Z = 0.005 X1 + X2 + 0.449 -0.070 + 0.903 Y, which Electronic Customer Relationship Management and the quality of service have yet to be effective in providing a positive influence for customer loyalty directly, but it must go through prior customer satisfaction as an intervening variable. Therefore, more companies should make improvements to the new way of communicating with customers via electronic media because it gives quite effective results for customer satisfaction in PT XL. Inaddition, PT XL should provide training and better development for the employees working in the company to improve the quality of service that can create customer loyalty.

Investigation of triaxiality in 54122-128Xe isotopes in the framework of sdg-IBM

Science.gov (United States)

Jafarizadeh, M. A.; Ranjbar, Z.; Fouladi, N.; Ghapanvari, M.

In this paper, a transitional interacting boson model (IBM) Hamiltonian in both sd-(IBM) and sdg-IBM versions based on affine SU(1, 1) Lie algebra is employed to describe deviations from the gamma-unstable nature of Hamiltonian along the chain of Xe isotopes. sdg-IBM Hamiltonian proposed a better interpretation of this deviation which cannot be explained in the sd-boson models. The nuclei studied have well-known γ bands close to the γ-unstable limit. The energy levels, B(E2) transition rates and signature splitting of the γ -vibrational band are calculated via the affine SU(1,1) Lie algebra. An acceptable degree of agreement was achieved based on this procedure. It is shown that in these isotopes the signature splitting is better reproduced by the inclusion of sdg-IBM. In none of them, any evidence for a stable, triaxial ground state shape is found.

A performance evaluation of the IBM 370/XT personal computer

Science.gov (United States)

Dominick, Wayne D. (Editor); Triantafyllopoulos, Spiros

1984-01-01

An evaluation of the IBM 370/XT personal computer is given. This evaluation focuses primarily on the use of the 370/XT for scientific and technical applications and applications development. A measurement of the capabilities of the 370/XT was performed by means of test programs which are presented. Also included is a review of facilities provided by the operating system (VM/PC), along with comments on the IBM 370/XT hardware configuration.

Users guide for the ANL IBM SPx

Energy Technology Data Exchange (ETDEWEB)

Gropp, W.; Lusk, E.

1994-12-01

This guide presents the features of the IBM SPx installed in the Mathematics and Computer Science Division at Argonne National Laboratory. The guide describes the available hardware and software, access policies, and hints for using the system productively.

A systematic review on the safety of Prostar XL versus ProGlide after TAVR and EVAR

Energy Technology Data Exchange (ETDEWEB)

Maniotis, Christos [2nd Cardiology Department, Hellenic Red Cross Hospital of Athens, Athens (Greece); Andreou, Constantinos; Karalis, Ioannis [Interventional Cardiology Department, University Hospital of Leiden, Leiden (Netherlands); Koutouzi, Giasemi [Interventional Radiology Department, Sahlgrenska University Hospital, Gothenburg (Sweden); Agelaki, Maria [2nd Cardiology Department, Hellenic Red Cross Hospital of Athens, Athens (Greece); Koutouzis, Michael, E-mail: koutouzismike@yahoo.gr [2nd Cardiology Department, Hellenic Red Cross Hospital of Athens, Athens (Greece)

2017-03-15

Background: Endovascular aortic aneurysm repair (EVAR) and transfemoral transcatheter aortic valve replacement (TAVR) are widely spreading minimally invasive procedures performed mainly through the femoral artery. Prostar XL and ProGlide vascular closure devices are used in clinical practice for the hemostasis in these procedures and they have been shown to be safe and effective. Purpose: The aim of our systematic review is to compare the safety of these two devices for percutaneous closure of large arteriotomies in patients undergoing TAVR and EVAR. Methods: We searched PubMed, EMBASE, Google Scholar and the Cochrane Central Register of Controlled Trials for all randomized and observational published studies that compared Prostar XL vs. ProGlide. Relative risk was calculated by random-effects model. Review Manager 5.1 was used for statistical analysis. Results: A total number of 2909 patients were included in our analysis. The rate of overall vascular complications did not differ between Prostar XL and ProGlide {RR 1.35 (0.80–2.29), p = 0.27}. In contrary, the risk ratio of all bleeding complications with Prostar XL compared to ProGlide was 1.82 (1.47–2.24, p < 0.001) and for major and life-threatening bleeding complications was 2.48 (1.65–3.73, p < 0001, suggesting a lower bleeding risk with ProGlide). No statistical difference was found between groups for end-stage acute kidney injury (AKI), with a risk ratio of 2.14 (0.81–5.66), p = 0.05. Finally, there were no differences in in-hospital and 30-days mortality rate between the two groups (1.41, 0.56–3.54, p = 0.46 and 1.43, 0.55–3.73, p = 0.47, respectively). Conclusions: Prostar XL is associated with greater risk of any bleeding as well as life threatening bleeding compared to the ProGlide device. However, no significant differences were observed in the rate of overall vascular complications, end stage AKI and in-hospital and 30-days mortality. - Highlights: • We present a systematic review

A systematic review on the safety of Prostar XL versus ProGlide after TAVR and EVAR

International Nuclear Information System (INIS)

Maniotis, Christos; Andreou, Constantinos; Karalis, Ioannis; Koutouzi, Giasemi; Agelaki, Maria; Koutouzis, Michael

2017-01-01

Background: Endovascular aortic aneurysm repair (EVAR) and transfemoral transcatheter aortic valve replacement (TAVR) are widely spreading minimally invasive procedures performed mainly through the femoral artery. Prostar XL and ProGlide vascular closure devices are used in clinical practice for the hemostasis in these procedures and they have been shown to be safe and effective. Purpose: The aim of our systematic review is to compare the safety of these two devices for percutaneous closure of large arteriotomies in patients undergoing TAVR and EVAR. Methods: We searched PubMed, EMBASE, Google Scholar and the Cochrane Central Register of Controlled Trials for all randomized and observational published studies that compared Prostar XL vs. ProGlide. Relative risk was calculated by random-effects model. Review Manager 5.1 was used for statistical analysis. Results: A total number of 2909 patients were included in our analysis. The rate of overall vascular complications did not differ between Prostar XL and ProGlide {RR 1.35 (0.80–2.29), p = 0.27}. In contrary, the risk ratio of all bleeding complications with Prostar XL compared to ProGlide was 1.82 (1.47–2.24, p < 0.001) and for major and life-threatening bleeding complications was 2.48 (1.65–3.73, p < 0001, suggesting a lower bleeding risk with ProGlide). No statistical difference was found between groups for end-stage acute kidney injury (AKI), with a risk ratio of 2.14 (0.81–5.66), p = 0.05. Finally, there were no differences in in-hospital and 30-days mortality rate between the two groups (1.41, 0.56–3.54, p = 0.46 and 1.43, 0.55–3.73, p = 0.47, respectively). Conclusions: Prostar XL is associated with greater risk of any bleeding as well as life threatening bleeding compared to the ProGlide device. However, no significant differences were observed in the rate of overall vascular complications, end stage AKI and in-hospital and 30-days mortality. - Highlights: • We present a systematic review

IBM PC based real time photon correlator [Paper No.:D2

International Nuclear Information System (INIS)

Kumaravadivelu, C.; Nageswaran, A.; Weling, S. A.

1993-01-01

The design aspects and development of IBM PC based real time photon correlator is presented. This system computes 64 auto-correlation functions in real time. Sample data is 4-bit wide. Correlation functions are computed in hard wired logic using discrete components. A combination of parallel and pipelined architecture is adopted to compute the correlation in realtime. A high speed controller generates the required control signals for the computing hardware and also provides handshake signals to IBM PC to access the computed results. IBM PC bus is extended and interfaced to correlation computing hardware. IBM PC collects the experimental parameters through user friendly menu and initiates the correlation hardware and continues to collect the correlation build ups and displays them on the screen. Extensive test and maintenance features are incorporated into the system. This system is developed for Material Science Division in Indira Gandhi Centre for Atomic Research (IGCAR) to study static and dynamic properties of macro molecules and colloidal particles in dispersion using light scattering technique. It can also be used to study the flow characteristics of sodium in nuclear reactors. It can be used in dynamic neutron scattering experiments. (author). 3 figs., 2 tabs

A Comparison of the Apple Macintosh and IBM PC in Laboratory Applications.

Science.gov (United States)

Williams, Ron

1986-01-01

Compares Apple Macintosh and IBM PC microcomputers in terms of their usefulness in the laboratory. No attempt is made to equalize the two computer systems since they represent opposite ends of the computer spectrum. Indicates that the IBM PC is the most useful general-purpose personal computer for laboratory applications. (JN)

In vitro and in vivo evaluation of the probiotic attributes of Lactobacillus kefiranofaciens XL10 isolated from Tibetan kefir grain.

Science.gov (United States)

Xing, Zhuqing; Tang, Wei; Geng, Weitao; Zheng, Yongna; Wang, Yanping

2017-03-01

Lactobacillus kefiranofaciens XL10, with a high yield of extracellular polysaccharide (EPS), is isolated from Tibetan kefir grain and benefits the health of human beings and has been considered to exhibit probiotic potential in vitro and in vivo. The probiotic function of the strain was studied extensively, viz., acid and bile salt tolerances, cell surface hydrophobicity and autoaggregation, the modulation of gut microbiota, and the distribution and colonization of XL10 in the mouse intestinal tract after oral administration. XL10 could survive 3-h incubation at pH 3.5 and exhibited cell surface hydrophobicity of ∼79.9% and autoaggregation of ∼27.8%. After continuous oral administration of XL10 for 2 weeks, the Bifidobacteriaceae family increased, accompanied by an observable decline in Proteobacteria phyla in the tested mice. Butyrivibrio and Pseudobutyrivibrio, recognized as butyric acid-producing bacteria, could also be detected at day 7 and day 14, respectively. The most abundant community in the mouse gut had formed by day 14. Additionally, we found that XL10 successfully adhered to the mucous tissue and colonized the ileum of the mice based on fluorescence imaging, flow cytometry, and qPCR. Our results suggested that XL10 has excellent probiotic properties and represents an alternative for exploitation in the development of novel functional foods.

Design of multichannel counting system for IBM PC and compatibles

International Nuclear Information System (INIS)

Majeed, B.; Ahmad, Z.; Osman, A.; Ysain, M.M.

1995-07-01

A Multichannel Counting System (MCCS), based on IBM-PC and compatible computer systems have been designed. The MCCS consists of a Multichannel Counting System plug-in interface card (MCCS-PC) for IBM PC and compatibles and a NIM-BIN module (MCCS-NB). The MCCS-PC provides simultaneous monitoring of upto seven independent SCA type inputs. An on board programmable timer provides elapsed time measurement. A menu-driven program for data acquisition and timer control has also been developed. (author) 8 figs

IBM 3480 tape cartridge

CERN Multimedia

1984-01-01

The 3480 tape format is a magnetic tape data storage format developed by IBM. The cartridge contains a single reel. IBM’s 3480 cartridge tape system sought to replace the traditional reels of magnetic tape in the computer center. Because of their speed, reliability, durability and low media cost, these tapes and tape drives are still in high demand. A hallmark of the genre is transferability. Tapes recorded with one tape drive are generally readable on another drive, even if the tape drives were built by different manufacturers.

EZVIDEO, DISSPLA Graphics Software Simulation on IBM PC

International Nuclear Information System (INIS)

1991-01-01

1 - Description of program or function: EZVIDEO simulates a subset of the DISSPLA plotting package to make plots on the IBM PC screen. Screen dumps can also be made to an attached LaserJet or Epson printer to make hard copy without using terminal emulators. The forerunner of EZVIDEO was called EZPLOT. 2 - Method of solution: The subroutines in the EZVIDEO system are based on the Hewlett Packard HP 9000 simulation of DISSPLA. These routines manipulate the pen movements on the screen and are also capable of capturing these same movements so that a hardcopy can be made to dot matrix or laser printer. 3 - Restrictions on the complexity of the problem: For plotting on the IBM PC, the plotting emulator PCPLOT is needed

Induction of Apoptosis by the Severe Acute Respiratory Syndrome Coronavirus 7a Protein Is Dependent on Its Interaction with the Bcl-XL Protein▿

Science.gov (United States)

Tan, Ying-Xim; Tan, Timothy H. P.; Lee, Marvin J.-R.; Tham, Puay-Yoke; Gunalan, Vithiagaran; Druce, Julian; Birch, Chris; Catton, Mike; Fu, Nai Yang; Yu, Victor C.; Tan, Yee-Joo

2007-01-01

The severe acute respiratory syndrome coronavirus (SARS-CoV) 7a protein, which is not expressed by other known coronaviruses, can induce apoptosis in various cell lines. In this study, we show that the overexpression of Bcl-XL, a prosurvival member of the Bcl-2 family, blocks 7a-induced apoptosis, suggesting that the mechanism for apoptosis induction by 7a is at the level of or upstream from the Bcl-2 family. Coimmunoprecipitation experiments showed that 7a interacts with Bcl-XL and other prosurvival proteins (Bcl-2, Bcl-w, Mcl-1, and A1) but not with the proapoptotic proteins (Bax, Bak, Bad, and Bid). A good correlation between the abilities of 7a deletion mutants to induce apoptosis and to interact with Bcl-XL was observed, suggesting that 7a triggers apoptosis by interfering directly with the prosurvival function of Bcl-XL. Interestingly, amino acids 224 and 225 within the C-terminal transmembrane domain of Bcl-XL are essential for the interaction with the 7a protein, although the BH3 domain of Bcl-XL also contributes to this interaction. In addition, fractionation experiments showed that 7a colocalized with Bcl-XL at the endoplasmic reticulum as well as the mitochondria, suggesting that they may form complexes in different membranous compartments. PMID:17428862

76 FR 174 - International Business Machines (IBM), Global Sales Operations Organization, Sales and...

Science.gov (United States)

2011-01-03

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,575; TA-W-74,575D] International Business Machines (IBM), Global Sales Operations Organization, Sales and Distribution Business Manager Roles; One Teleworker Located in Charleston, WV; International Business Machines (IBM), Global Sales Operations Organization, Sales and...

Microscopic IBM-1 description of collective states in 128Ce

Directory of Open Access Journals (Sweden)

Mikhajlov V. M.

2012-12-01

Full Text Available Microscopical quasiparticle theory is developed to calculate the IBM-1 parameters entering the Hamiltonian and E2–operator. The theory takes into account the impact of noncollective phonons and predicts alterations of the superconducting properties along the excitation spectrum, whereas the most collective phonon (the image of the IBM d-boson is practically invariable. Calculations of the energy spectrum and probabilities of E2–transitions (without effective nucleon charges were performed for 128Ce. The results obtained are in satisfactory agreement with experimental data.

PC-Link historical data base system MODCOMP/IBM at link for neutral particle beam operation

International Nuclear Information System (INIS)

Thurgood, P.

1989-12-01

''PC-Link'' is a combination of hardware and software that connects an IBM PC/AT to a MODCOMP minicomputer. It is designed as an aid to the Neutral Beam operations coordinator during injection into the DIII-D tokamak project. An IBM PC/AT is linked to 4 MODCOMP ''realtime'' acquisition systems, each of which controls 2 neutral particle beam sources. At various points in the shot sequence, data is sent to the IBM PC/AT. This data can then be integrated with the data from the other sources into tables or graphics displays for use by the Beam Coordinator. In this way, the coordinator gets realtime feedback on the relative settings and performance of the sources and can observe trends within a particular source at one location. The PC- Link is used for observing relative timing information and for post shot historical archiving. The concept of the PC-Link was originally proposed several years ago. In April 1988, in-house implementation of the link software was begun. The PC-Link receives approximately 2 Kbytes of data per source per shot. This data is converted from MODCOMP format to IBM PC format and archived to disk. The last 280 shots per source are stored to disk to observe trends. The data can be displayed in a number of formats depending upon the situation. For example, prior to a shot, the beam MODCOMPs are sent timing information from the DIII-D tokamak control system. This data is echoed on the PC in a graphical representation displaying all 8 sources. At the end of the shot, the actual running times are displayed along with the requested settings. Any subset of the Historical data may be displayed either graphically or in tables for realtime comparisons between sources. This system is designed for realtime use, not for complete archiving purposes. This same data is also sent to a VAX computer for full integration into the archive database. This system is easily upgradable and extremely versatile. 4 figs

IBM-PC-based reactor neutronics analysis package

International Nuclear Information System (INIS)

Nigg, D.W.; Wessol, D.E.; Grimesey, R.A.; Parsons, D.K.; Wheeler, F.J.; Yoon, W.Y.; Lake, J.A.

1985-01-01

Technical advances over the past few years have led to a situation where a wide range of complex scientific computations can now be done on properly configured microcomputers such as the IBM-PC (personal computer). For a number of reasons, including security, economy, and user convenience, the development of a comprehensive system of reactor neutronics codes suitable for operation on the IBM-PC has been undertaken at the Idaho National Engineering Laboratory (INEL). It is anticipated that a PC-based code system could also have wide applicability in the nuclear engineering education community since conversion of software generated by national laboratories and others to college and university mainframe hardware has historically been a time-consuming process that has sometimes met with only limited success. This paper discusses the philosophy behind the INEL reactor neutronics PC code system and describes those parts of the system that are currently complete, those that are now under development, and those that are still in the planning stage

Correspondence between phenomenological and IBM-1 models of even isotopes of Yb

Science.gov (United States)

A. Okhunov, A.; I. Sharrad, F.; Anwer, A. Al-Sammarraie; U. Khandaker, M.

2015-08-01

Energy levels and the reduced probability of E2- transitions for ytterbium isotopes with proton number Z = 70 and neutron numbers between 100 and 106 have been calculated through phenomenological (PhM) and interacting boson (IBM-1) models. The predicted low-lying levels (energies, spins and parities) and the reduced probability for E2- transitions results are reasonably consistent with the available experimental data. The predicted low-lying levels (gr-, β1- and γ1- band) produced in the PhM are in good agreement with the experimental data compared with those by IBM-1 for all nuclei of interest. In addition, the phenomenological model was successful in predicting the β2-, β3-, β4-, γ2- and 1+ - band while it was a failure with IBM-1. Also, the 3+- band is predicted by the IBM-1 model for 172Yb and 174Yb nuclei. All calculations are compared with the available experimental data. Supported by Fundamental Research Grant Scheme (FRGS) of Ministry of Higher Education of Malaysia (FRGS13-074-0315), Islamic Development Bank (IDB) (36/11201905/35/IRQ/D31, 37/IRQ/P30)

75 FR 60141 - International Business Machines (IBM), Global Technology Services Delivery Division, Including On...

Science.gov (United States)

2010-09-29

... 25, 2010, applicable to workers of International Business Machines (IBM), Global Technology Services... hereby issued as follows: All workers of International Business Machines (IBM), Global Technology... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,164] International Business...

Desk-top publishing using IBM-compatible computers.

Science.gov (United States)

Grencis, P W

1991-01-01

This paper sets out to describe one Medical Illustration Departments' experience of the introduction of computers for desk-top publishing. In this particular case, after careful consideration of all the options open, an IBM-compatible system was installed rather than the often popular choice of an Apple Macintosh.

Networking DEC and IBM computers

Science.gov (United States)

Mish, W. H.

1983-01-01

Local Area Networking of DEC and IBM computers within the structure of the ISO-OSI Seven Layer Reference Model at a raw signaling speed of 1 Mops or greater are discussed. After an introduction to the ISO-OSI Reference Model nd the IEEE-802 Draft Standard for Local Area Networks (LANs), there follows a detailed discussion and comparison of the products available from a variety of manufactures to perform this networking task. A summary of these products is presented in a table.

76 FR 32231 - International Business Machines (IBM), Sales and Distribution Business Unit, Global Sales...

Science.gov (United States)

2011-06-03

... for the workers and former workers of International Business Machines (IBM), Sales and Distribution... reconsideration alleges that IBM outsourced to India and China. During the reconsideration investigation, it was..., Armonk, New York. The subject worker group supply computer software development and maintenance services...

Radioimmunoassay data processing program for IBM PC computers

International Nuclear Information System (INIS)

1989-06-01

The Medical Applications Section of the International Atomic Energy Agency (IAEA) has previously developed several programs for use on the Hewlett-Packard HP-41C programmable calculator to facilitate better quality control in radioimmunoassay through improved data processing. The program described in this document is designed for off-line analysis using an IBM PC (or compatible) for counting data from standards and unknown specimens (i.e. for analysis of counting data previously recorded by a counter), together with internal quality control (IQC) data both within and between batch. The greater computing power of the IBM PC has enabled the imprecision profile and IQC control curves which were unavailable on the HP-41C version. It is intended that the program would make available good data processing capability to laboratories having limited financial resources and serious problems of quality control. 3 refs

Caso de estudio. IBM: ¿Más allá del conocimiento...?

OpenAIRE

Vernaza Pacheco, Pablo José; Velásquez Vásquez, Francisco Orlando

2006-01-01

El caso muestra cómo los presidentes Louis Gerstner y Samuel Palmesano lograron influir en un cambio positivo de las personas, sus valores y conocimientos, para que IBM recuperara el liderazgo en el mercado. IBM empieza a generar conocimiento y logra ser una de las empresas que más patentes ha registrado en los Estados Unidos durante la última década. El caso también plantea dilemas donde se cuestiona si la investigación y el conocimiento adquirido por las empresas ha servido o no para ...

BRT-1 code for IBM 370/135

International Nuclear Information System (INIS)

Preda, I.

1976-01-01

BRT-1 is a transport code to obtain the thermal neutrons spectrum, point dependent, in one reactor cell. The code BRT-1 described in this paper, is the code BRT-1, written in FORTRAN IV language for the computer UNIVAC 1108 with CSCX operating system, converted for the computer IBM 370/135 disk operating system. (author)

Jazz亮相IBM RSDC

Institute of Scientific and Technical Information of China (English)

无

2008-01-01

6月2号,IBM在IBM Rational Software开发会议上宣布,今年年底前将有20款采用Jazz技术的产品出炉,而且最终是开放源代码的。Jazz并不是一个产品而是一项技术,这项技术主要能够加强企业在协同作业上的能力。Jazz的原意是爵士音乐,最早的爵士音乐融合了欧洲的古典音乐、军乐、流行音乐和舞曲。

Fabled IBM Tank nears launch without key features

CERN Multimedia

2003-01-01

"IBM is preparing to roll out the TotalStorage SAN File System, the ballyhooed, renamed, much delayed Storage Tank the company's been working on for ages, although it now appears some of its key capabilities won't appear until next year in a later version" (1 page).

Bus and Tag Terminators for IBM system/360

CERN Multimedia

Control units were connected to the channels with "Bus and Tag" cable pairs. The bus cables carried the address and data information and the tag cables identified what data was on the bus. There were three general types of bus-and-tag cables produced by IBM.

Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak.

Science.gov (United States)

Lauf, Peter K; Alqahtani, Tariq; Flues, Karin; Meller, Jaroslaw; Adragna, Norma C

2015-01-01

In silico analysis predicts interaction between Na-K-ATPase (NKA) and Bcl-2 protein canonical BH3- and BH1-like motifs, consistent with NKA inhibition by the benzo-phenanthridine alkaloid chelerythrine, a BH3 mimetic, in fetal human lens epithelial cells (FHLCs) (Lauf PK, Heiny J, Meller J, Lepera MA, Koikov L, Alter GM, Brown TL, Adragna NC. Cell Physiol Biochem 31: 257-276, 2013). This report establishes proof of concept: coimmunoprecipitation and immunocolocalization showed unequivocal and direct physical interaction between NKA and Bcl-2 proteins. Specifically, NKA antibodies (ABs) coimmunoprecipitated BclXL (B-cell lymphoma extra large) and BAK (Bcl-2 antagonist killer) proteins in FHLCs and A549 lung cancer cells. In contrast, both anti-Bcl-2 ABs failed to pull down NKA. Notably, the molecular mass of BAK1 proteins pulled down by NKA and BclXL ABs appeared to be some 4-kDa larger than found in input monomers. In silico analysis predicts these higher molecular mass BAK1 proteins as alternative splicing variants, encoding 42 amino acid (aa) larger proteins than the known 211-aa long canonical BAK1 protein. These BAK1 variants may constitute a pool separate from that forming mitochondrial pores by specifically interacting with NKA and BclXL proteins. We propose a NKA-Bcl-2 protein ternary complex supporting our hypothesis for a special sensor role of NKA in Bcl-2 protein control of cell survival and apoptosis. Copyright © 2015 the American Physiological Society.

Performance of the IBM synchrotron X-ray source for lithography

International Nuclear Information System (INIS)

Archie, C.

1993-01-01

The compact superconducting synchrotron X-ray source at the IBM Advanced Lithography Facility in East Fishkill, New York has been in service to customers since the start of 1992. It availability during scheduled time is greater than 90%, with recent months frequently surpassing 95%. Data on the long-term behavior of the X-ray source properties and subsystem performance are now available. The full system continues to meet all specifications and even to surpass them in key areas. Measured electron beam properties such as beam size, short- and long-term positional stability, and beam life are presented. Lifetimes greater than 20 hours for typical stored beams have significantly simplified operations and increased availability compared to projections. This paper also describes some unique features of this X-ray source and goes beyond a discussion of downtime to describe the efforts behind the scenes to maintain and operate it

Performance of large-scale scientific applications on the IBM ASCI Blue-Pacific system

International Nuclear Information System (INIS)

Mirin, A.

1998-01-01

The IBM ASCI Blue-Pacific System is a scalable, distributed/shared memory architecture designed to reach multi-teraflop performance. The IBM SP pieces together a large number of nodes, each having a modest number of processors. The system is designed to accommodate a mixed programming model as well as a pure message-passing paradigm. We examine a number of applications on this architecture and evaluate their performance and scalability

The web server of IBM's Bioinformatics and Pattern Discovery group: 2004 update.

Science.gov (United States)

Huynh, Tien; Rigoutsos, Isidore

2004-07-01

In this report, we provide an update on the services and content which are available on the web server of IBM's Bioinformatics and Pattern Discovery group. The server, which is operational around the clock, provides access to a large number of methods that have been developed and published by the group's members. There is an increasing number of problems that these tools can help tackle; these problems range from the discovery of patterns in streams of events and the computation of multiple sequence alignments, to the discovery of genes in nucleic acid sequences, the identification--directly from sequence--of structural deviations from alpha-helicity and the annotation of amino acid sequences for antimicrobial activity. Additionally, annotations for more than 130 archaeal, bacterial, eukaryotic and viral genomes are now available on-line and can be searched interactively. The tools and code bundles continue to be accessible from http://cbcsrv.watson.ibm.com/Tspd.html whereas the genomics annotations are available at http://cbcsrv.watson.ibm.com/Annotations/.

Quantitative analysis and IBM SPSS statistics a guide for business and finance

CERN Document Server

Aljandali, Abdulkader

2016-01-01

This guide is for practicing statisticians and data scientists who use IBM SPSS for statistical analysis of big data in business and finance. This is the first of a two-part guide to SPSS for Windows, introducing data entry into SPSS, along with elementary statistical and graphical methods for summarizing and presenting data. Part I also covers the rudiments of hypothesis testing and business forecasting while Part II will present multivariate statistical methods, more advanced forecasting methods, and multivariate methods. IBM SPSS Statistics offers a powerful set of statistical and information analysis systems that run on a wide variety of personal computers. The software is built around routines that have been developed, tested, and widely used for more than 20 years. As such, IBM SPSS Statistics is extensively used in industry, commerce, banking, local and national governments, and education. Just a small subset of users of the package include the major clearing banks, the BBC, British Gas, British Airway...

What history tells us XL. The success story of the expression ...

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences; Volume 41; Issue 1. What history tells us XL. The success story of the expression 'genome editing'. Michel Morange. Series Volume 41 Issue 1 March 2016 pp 9-11. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/041/01/0009-0011 ...

LANSCE Beam Current Limiter (XL)

International Nuclear Information System (INIS)

Gallegos, F.R.; Hall, M.J.

1997-01-01

The Radiation Security System (RSS) at the Los Alamos Neutron Science Center (LANSCE) is an engineered safety system that provides personnel protection from prompt radiation due to accelerated proton beams. The Beam Current Limiter (XL), as an active component of the RSS, limits the maximum average current in a beamline, thus the current available for a beam spill accident. Exceeding the pre-set limit initiates action by the RSS to mitigate the hazard (insertion of beam stoppers in the low energy beam transport). The beam limiter is an electrically isolated, toroidal transformer and associated electronics. The device was designed to continuously monitor beamline currents independent of any external timing. Fail-safe operation was a prime consideration in its development. Fail-safe operation is defined as functioning as intended (due to redundant circuitry), functioning with a more sensitive fault threshold, or generating a fault condition. This report describes the design philosophy, hardware, implementation, operation, and limitations of the device

A framework for WRF to WRF-IBM grid nesting to enable multiscale simulations

Energy Technology Data Exchange (ETDEWEB)

Wiersema, David John [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Univ. of California, Berkeley, CA (United States); Lundquist, Katherine A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Chow, Fotini Katapodes [Univ. of California, Berkeley, CA (United States)

2016-09-29

With advances in computational power, mesoscale models, such as the Weather Research and Forecasting (WRF) model, are often pushed to higher resolutions. As the model’s horizontal resolution is refined, the maximum resolved terrain slope will increase. Because WRF uses a terrain-following coordinate, this increase in resolved terrain slopes introduces additional grid skewness. At high resolutions and over complex terrain, this grid skewness can introduce large numerical errors that require methods, such as the immersed boundary method, to keep the model accurate and stable. Our implementation of the immersed boundary method in the WRF model, WRF-IBM, has proven effective at microscale simulations over complex terrain. WRF-IBM uses a non-conforming grid that extends beneath the model’s terrain. Boundary conditions at the immersed boundary, the terrain, are enforced by introducing a body force term to the governing equations at points directly beneath the immersed boundary. Nesting between a WRF parent grid and a WRF-IBM child grid requires a new framework for initialization and forcing of the child WRF-IBM grid. This framework will enable concurrent multi-scale simulations within the WRF model, improving the accuracy of high-resolution simulations and enabling simulations across a wide range of scales.

IBM-i ja Lenovo juhid külastasid Eestit

Index Scriptorium Estoniae

2006-01-01

8.-9. maini 2006. a. viibisid Tallinnas IBM-Lenovo Alliance'i viitsepresident Simon L. Porter ja Lenovo Soome regiooni juhataja Jukka Mäntylä, kes kohtusid kohaliku IT-pressiga ning esitlesid Tallinna Botaanikaaia Palmimaja seminarikeskuses mõlema firma uudiseid

Point Climat no. 30 'Seeing the forest from the trees: Infrastructure Investment and 'systemic' GHG impacts - Lessons from the Keystone XL'

International Nuclear Information System (INIS)

Cochran, Ian; Morel, Romain

2013-01-01

Among the publications of CDC Climat Research, 'Climate Briefs' presents, in a few pages, hot topics in climate change policy. This issue addresses the following points: - Achieving the 'energy transition', it is necessary to ask how individual investments support or hinder progress towards a low-carbon, energy-efficient future. This requires a a systemic approach - or 'scope 4' analysis. - As demonstrated by the Keystone XL Oil pipeline project in North America, even when individual pieces of infrastructure emit relatively low levels of direct greenhouse gases, they can foster the continuation of system that will continue to favor, and financially reward, investments supporting a fossil fuel-based economy. - Effectively addressing greenhouse gas emissions and fully understanding the impact of individual projects - both as individual elements and lynch pins of a larger system - will require a wider scope of integration into both project development and financial decision making than currently occurs

IBM Eesti loodab ELiga liitumisest tulu lõigata / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2003-01-01

Maailma juhtiva infotehnoloogiafirma IBM Eesti tütarettevõte näeb Eesti liitumises Euroopa Liiduga endale uusi võimalusi Euroopa turul, eriti dokumendihalduse valdkonnas. Diagramm: IBMi aktsia viimased kolm aastat

Comparison of the AMDAHL 470V/6 and the IBM 370/195 using benchmarks

Energy Technology Data Exchange (ETDEWEB)

Snider, D.R.; Midlock, J.L.; Hinds, A.R.; Engert, D.E.

1976-03-01

Six groups of jobs were run on the IBM 370/195 at the Applied Mathematics Division (AMD) of Argonne National Laboratory using the current production versions of OS/MVT 21.7 and ASP 3.1. The same jobs were then run on an AMDAHL 470V/6 at the AMDAHL manufacturing facilities in Sunnyvale, California, using the identical operating systems. Performances of the two machines are compared. Differences in the configurations were minimized. The memory size on each machine was the same, all software which had an impact on run times was the same, and the I/O configurations were as similar as possible. This allowed the comparison to be based on the relative performance of the two CPU's. As part of the studies preliminary to the acquisition of the IBM 195 in 1972, two of the groups of jobs had been run on a CDC 7600 by CDC personnel in Arden Hills, Minnesota, on an IBM 360/195 by IBM personnel in Poughkeepsie, New York, and on the AMD 360/50/75 production system in June, 1971. 6 figures, 9 tables.

Removal of copper (II) from aqueous solutions by flotation using polyaluminum chloride silicate (PAX-XL60 S) as coagulant and carbonate ion as activator.

Science.gov (United States)

Ghazy, S E; Mahmoud, I A; Ragab, A H

2006-01-01

Flotation is a separation technology for removing toxic heavy metal ions from aqueous solutions. Here a simple and rapid flotation procedure is presented for the removal of copper(II) from aqueous solutions. It is based on the use of polyaluminum chloride silicate (PAX-XL60 S) as coagulant and flocculent, carbonate ion as activator and oleic acid (HOL) as surfactant. Both ion and precipitate flotation are included depending on the solution pH. Ion and precipitate flotation in the aqueous HOL-PAX-XL60 S-Cu2+-CO3(2-) system gave powerful preferential removal of Cu2+ (F -100%) over the HOL-PAX-XL60 S-Cu2+ system containing no CO3(2+) ion (F approximately 86%). The role of CO3(2-) ion is also evident from decreasing the dose of PAX-XL60 S from 700 mg l(-1) to 200 mg l(-1). The other parameters, influencing the flotation process, namely: metal ion, surfactant and PAX-XL60 S concentrations, ionic strength, temperature and foreign ions were examined. Moreover, the procedure was successfully applied to recover Cu2+ ions from different volumes up to 11 and from natural water samples.

AGRIS: Categorization and information retrieval based on IBM's IRMS

International Nuclear Information System (INIS)

Schmid, H.; Leatherdale, D.

1976-01-01

The subject breakdown of the AGRIS data base by categories interlinked with object and geographical codes is described. The use of these categories and codes in a mechanized information retrieval system is then considered. The system is a modification of IBM's Information Retrieval and Management System (IRMS); it allows for batch processing on an IBM/360 or /370 computer operated under OS or VS. As IRMS was developed for use with a controlled vocabulary, the search possibilities on the AGRIS files are necessarily limited. An artificial vocabulary is presented, derived from the AGRIS subject categories, object codes, geographic codes, language codes, and bibliographic data: type of record, literary indicator, volume/issue number, and the country code of the submitting centre. The use of the IRMS system for AGRIS is described, with details of programming deliberately omitted. Program descriptions with data set definitions and file formats are presented separately

IBM SPSS modeler essentials effective techniques for building powerful data mining and predictive analytics solutions

CERN Document Server

McCormick, Keith; Wei, Bowen

2017-01-01

IBM SPSS Modeler allows quick, efficient predictive analytics and insight building from your data, and is a popularly used data mining tool. This book will guide you through the data mining process, and presents relevant statistical methods which are used to build predictive models and conduct other analytic tasks using IBM SPSS Modeler. From ...

IBM parameters derived from realistic shell-model Hamiltonian via Hn-cooling method

International Nuclear Information System (INIS)

Nakada, Hitoshi

1997-01-01

There is a certain influence of non-collective degrees-of-freedom even in lowest-lying states of medium-heavy nuclei. This influence seems to be significant for some of the IBM parameters. In order to take it into account, several renormalization approaches have been applied. It has been shown in the previous studies that the influence of the G-pairs is important, but does not fully account for the fitted values. The influence of the non-collective components may be more serious when we take a realistic effective nucleonic interaction. To incorporate this influence into the IBM parameters, we employ the recently developed H n -cooling method. This method is applied to renormalize the wave functions of the states consisting of the SD-pairs, for the Cr-Fe nuclei. On this ground, the IBM Hamiltonian and transition operators are derived from corresponding realistic shell-model operators, for the Cr-Fe nuclei. Together with some features of the realistic interaction, the effects of the non-SD degrees-of-freedom are presented. (author)

IBM Sametime 852 Administration Guide

CERN Document Server

Davis, Gabriella; Duff, Thomas

2011-01-01

The IBM Lotus Sametime 8.5.2 Administration Guide uses a practical, no-nonsense approach to give you the essential information you need. Using realistic scenarios, you learn how to configure and maintain your environment to meet your needs and take advantage of the flexibility offered in Sametime 8.5.2. If you are responsible for installing and administering Sametime 8.5.2, then this book is for you. If you're completely new to Sametime administration, this book will serve as your roadmap. If you're making the jump from a prior version of Sametime, then you'll see how Sametime 8.5.2 differs an

An Apple for Your IBM PC--The Quadlink Board.

Science.gov (United States)

Owen, G. Scott

1984-01-01

Describes nature and installation of the QUADLINK board which allows Apple software to be run on IBM PC microcomputers. Although programs tested ran without problems, users should test their own programs since there are some copy protection schemes that can baffle the board. (JN)

Mathematics Programming on the Apple II and IBM PC.

Science.gov (United States)

Myers, Roy E.; Schneider, David I.

1987-01-01

Details the features of BASIC used in mathematics programming and provides the information needed to translate between the Apple II and IBM PC computers. Discusses inputing a user-defined function, setting scroll windows, displaying subscripts and exponents, variable names, mathematical characters and special symbols. (TW)

The Little Giant: The IBM Series/1 in Library Applications.

Science.gov (United States)

Hendricks, Donald D.; Manino, Glenn

1987-01-01

This description of the use of IBM Series/1 minicomputers to implement a library automation system includes discussion of current functions of the system, the system configuration, communications capabilities, software, and cost factors. (CLB)

Vector and parallel computing on the IBM ES/3090, a powerful approach to solving problems in the utility industry

International Nuclear Information System (INIS)

Bellucci, V.J.

1990-01-01

This paper describes IBM's approach to parallel computing using the IBM ES/3090 computer. Parallel processing concepts were discussed including its advantages, potential performance improvements and limitations. Particular applications and capabilities for the IBM ES/3090 were presented along with preliminary results from some utilities in the application of parallel processing to simulation of system reliability, air pollution models, and power network dynamics

IBM PC based automatic drive system for Bulat setup

International Nuclear Information System (INIS)

Luchaninov, A.A.; Tolok, V.T.

1999-01-01

Non-expensive computer drive system for Bulat setup is described. System's hardware consists of IBM PC and conjunction block, providing 12 output channels, Software includes the main program, utilities and technology processes database. System may be used at surface modification processes, especially multilayer multicomponent coatings deposition

Performing data analysis using IBM SPSS

CERN Document Server

Meyers, Lawrence S; Guarino, A J

2013-01-01

This book is designed to be a user's guide for students and other interested readers to perform statistical data analysis with IBM SPSS, which is a major statistical software package used extensively in academic, government, and business settings. This book addresses the needs, level of sophistication, and interest in introductory statistical methodology on the part of undergraduate and graduate students in social and behavioral science, business, health-related, and education programs.  Each chapter covers a particular statistical procedure and has the following format: an example pr

Inference in media space. The case of IBM Software Executive Briefing Center - Rome

Directory of Open Access Journals (Sweden)

Toni Marino

2014-11-01

Full Text Available In our paper we apply Peirce's model of Arguments (Statistical Deduction, Probabilistic Deduction, Induction and Abduction to a communication process where negotiating sense and meanings is emphasized. We selected a communication space where everything is planned as a medium of sense (video terminals, screens, lights, etc. namely the IBM Software Executive Briefing Center in Italy, a workplace used to exchange views, negotiate or transact. It is based in Rome in the same building as the International Development Laboratory of the IBM Software Group. The Software Center is the place where IBM welcomes its potential customers and has the opportunity to show them its technology and offer solutions. This paper focuses on "media space" in the Center which is structured by the seller according to his/her idea of the buyer's interpretive process. This paper analyzes the roles of visual codes in the allocation of functions. It also looks into the relation between the symbolism of the company with its marketing, past history and media space in order to define the buyer's typology of inference (deduction, induction or abduction in relation to the communication strategy of the media space design. The research is conducted directly in the field by interviewing the Manager of the IBM Center as well as asking people who use it to fill in an anonymous questionnaire, which analyses both the media space and the plan of the building.

Project SERAPHIM Report.

Science.gov (United States)

Moore, John W.

1983-01-01

Lists and briefly describes computer programs recently added to those currently available from Project SERAPHIM. Program name, subject, hardware, author, supplier, and cost are provided in separate listings for Apple, PET, TRS-80 I or III, IBM, VIC-20, TERAK, and PDP-11 microcomputers. Includes corrections for two current Apple programs. (JN)

Project Final Report: HPC-Colony II

Energy Technology Data Exchange (ETDEWEB)

Jones, Terry R [ORNL; Kale, Laxmikant V [University of Illinois, Urbana-Champaign; Moreira, Jose [IBM T. J. Watson Research Center

2013-11-01

This report recounts the HPC Colony II Project which was a computer science effort funded by DOE's Advanced Scientific Computing Research office. The project included researchers from ORNL, IBM, and the University of Illinois at Urbana-Champaign. The topic of the effort was adaptive system software for extreme scale parallel machines. A description of findings is included.

Whole Module Offgas Test Report: Space-Xl Dragon Module

Science.gov (United States)

James, John T.

2012-01-01

On September 26 and September 28,2012 a chemist from the JSC Toxicology Group acquired samples of air in 500 m1 evacuated canisters from the sealed Space-Xl Dragon Module. One sample was also acquired from Space-X Facility near the module at the start of the test. Samples of the module air were taken in triplicate once the module had been sealed, and then taken again in triplicate 1.98 days later. Ofthe triplicate samples, the first served as a line purge, and the last two were analyzed. The results of 5 samples are reported.

IBM SPSS statistics 19 made simple

CERN Document Server

Gray, Colin D

2012-01-01

This new edition of one of the most widely read textbooks in its field introduces the reader to data analysis with the most powerful and versatile statistical package on the market: IBM SPSS Statistics 19. Each new release of SPSS Statistics features new options and other improvements. There remains a core of fundamental operating principles and techniques which have continued to apply to all releases issued in recent years and have been proved to be worth communicating in a small volume. This practical and informal book combines simplicity and clarity of presentation with a comprehensive trea

Maintenance of Microcomputers. Manual and Apple II Session, IBM Session.

Science.gov (United States)

Coffey, Michael A.; And Others

This guide describes maintenance procedures for IBM and Apple personal computers, provides information on detecting and diagnosing problems, and details diagnostic programs. Included are discussions of printers, terminals, disks, disk drives, keyboards, hardware, and software. The text is supplemented by various diagrams. (EW)

The algebraic manipulation program DIRAC on IBM personal computers

International Nuclear Information System (INIS)

Grozin, A.G.; Perlt, H.

1989-01-01

The version DIRAC (2.2) for IBM compatible personal computers is described. It is designed to manipulate algebraically with polynomials and tensors. After a short introduction concerning implementation and usage on personal computers an example program is given. It contains a detailed user's guide to DIRAC (2.2) and, additionally some useful applications. 4 refs

Design of a 1-chip IBM-3270 protocol handler

NARCIS (Netherlands)

Spaanenburg, L.

1989-01-01

The single-chip design of a 20MHz IBM-3270 coax protocol handler in a conventional 3 μ CMOS process-technology is discussed. The harmonious combination of CMOS circuit tricks and high-level design disciplines allows the 50k transistor design to be compiled and optimized into a 35 mm**2 chip in 4

[A comparison of rebound tonometry (ICare) with TonoPenXL and Goldmann applanation tonometry].

Science.gov (United States)

Schreiber, W; Vorwerk, C K; Langenbucher, A; Behrens-Baumann, W; Viestenz, A

2007-04-01

Goldmann applanation tonometry and dynamic contour tonometry (PASCAL) are two well established slit lamp mounted tonometric methods. Intraocular pressure measurement in bedridden patients and children is often only possible using hand held tonometers (TonoPenXL, Perkins tonometer, Draeger tonometer). This study was performed to evaluate the hand held ICare tonometer, which is based on the rebound method. A total of 102 eyes were examined by two highly experienced ophthalmologists for: 1) ophthalmological status, 2) central corneal power (Zeiss IOL-Master), 3) central corneal thickness (Tomey ultrasound pachymetry, five successive measurements, SDr=0.592-0.642; p<0.001). There was a great intra-individual variability of up to 17 mmHg between the GAT, TonoPenXL and ICare methods. The ICare tonometer is easy to handle and high reliability. The data are comparable with those from the Goldmann tonometer. A tonography effect of 0.6 mmHg in the successive measurement series was found.

Data transfer from Beckman LS 5800 liquid scintillation counters to IBM personal computers.

Science.gov (United States)

Maan, A C

1985-09-01

This communication describes a short routine in BASICA for the IBM-PC, written to collect data from a Beckman liquid scintillation counter. In the form presented here the routine converts incoming bytes into separate lines and saves these lines in a file. There are many possible applications for further use of the data in these files. A few suggestions are given as to the format in which data can be stored and how to process these data automatically after all samples have been counted. The only hardware needed is an asynchronous communications adapter for the IBM-PC and an RS232 cable.

A tale of two arcs? Plate tectonics of the Izu-Bonin-Mariana (IBM) arc using subducted slab constraints

Science.gov (United States)

Wu, J. E.; Suppe, J.; Renqi, L.; Kanda, R. V. S.

2014-12-01

Published plate reconstructions typically show the Izu-Bonin Marianas arc (IBM) forming as a result of long-lived ~50 Ma Pacific subduction beneath the Philippine Sea. These reconstructions rely on the critical assumption that the Philippine Sea was continuously coupled to the Pacific during the lifetime of the IBM arc. Because of this assumption, significant (up to 1500 km) Pacific trench retreat is required to accommodate the 2000 km of Philippine Sea/IBM northward motion since the Eocene that is constrained by paleomagnetic data. In this study, we have mapped subducted slabs of mantle lithosphere from MITP08 global seismic tomography (Li et al., 2008) and restored them to a model Earth surface to constrain plate tectonic reconstructions. Here we present two subducted slab constraints that call into question current IBM arc reconstructions: 1) The northern and central Marianas slabs form a sub-vertical 'slab wall' down to maximum 1500 km depths in the lower mantle. This slab geometry is best explained by a near-stationary Marianas trench that has remained +/- 250 km E-W of its present-day position since ~45 Ma, and does not support any significant Pacific slab retreat. 2) A vanished ocean is revealed by an extensive swath of sub-horizontal slabs at 700 to 1000 km depths in the lower mantle below present-day Philippine Sea to Papua New Guinea. We call this vanished ocean the 'East Asian Sea'. When placed in an Eocene plate reconstruction, the East Asian Sea fits west of the reconstructed Marianas Pacific trench position and north of the Philippine Sea plate. This implies that the Philippine Sea and Pacific were not adjacent at IBM initiation, but were in fact separated by a lost ocean. Here we propose a new IBM arc reconstruction constrained by subducted slabs mapped under East Asia. At ~50 Ma, the present-day IBM arc initiated at equatorial latitudes from East Asian Sea subduction below the Philippine Sea. A separate arc was formed from Pacific subduction below

IbM Kelompok Usaha Produk Olahan Susu Segar Di Dusun Boyong Desa Hargobinangun, Sleman Yogyakarta

OpenAIRE

Rahayu, Ninik Sri; Indrawati, Sri

2014-01-01

Micro, IBM's partner program (science and technology to the Community) are SMEs Heroine Boyong I (stick milk) and Heroine Boyong II (milk candy). Both are micro-scale industry based on fresh dairy product businesses.IBM program on SME partners focused on the aspects of production and management. All activities in the production aspect functioned to improve the capacity and quality of production and increase dairy product variants. While aspects of management consists of: marketing, financial ...

Measurements of intraocular pressure by Goldmann tonometry, Tonopen XL, and the transpalpebral tonometer, TGDc-01, after penetrating keratoplasty: a comparativye study.

Science.gov (United States)

Shemesh, Gabi; Waisbourd, Michael; Varssano, David; Michaeli, Adi; Lazar, Moshe; Kurtz, Shimon

2009-08-01

The aim of this study was to compare intraocular pressure (IOP) measurements obtained by Goldmann tonometry (GT), the Tonopen XL, and a new transpalpebral tonometer, TGDc-01, in eyes that had undergone penetrating keratoplasty (PKP). IOP was measured in post-PKP eyes by means of GT, Tonopen XL, and TGDc-01. Central corneal thickness measurements were also obtained for all eyes. Forty-five eyes of 43 patients were enrolled in the study. The mean IOP difference (+/-SD) was -0.42 +/- 5.83 mm Hg between GT and Tonopen and 3.20 +/- 7.55 mm Hg between GT and TGDc-01. The correlation coefficient was 0.84 between GT and Tonopen XL (P tonometer is simply inaccurate or whether avoiding contact with the corneal graft by measuring IOP through the eyelid enables it to provide more accurate IOP readings than those obtained by transcorneal techniques.

An IBM-3 hamiltonian from a multi-j-shell model

International Nuclear Information System (INIS)

Evans, J.A.; Elliott, J.P.; Lac, V.S.; Long, G.L.

1995-01-01

The number and isospin dependence of the hamiltonian in the isospin invariant form (IBM-3) of the boson model is deduced from a seniority mapping onto a shell-model system of several shells. The numerical results are compared with earlier work for a single j-shell. (orig.)

LERC-SLAM - THE NASA LEWIS RESEARCH CENTER SATELLITE LINK ATTENUATION MODEL PROGRAM (IBM PC VERSION)

Science.gov (United States)

Manning, R. M.

1994-01-01

antenna required to establish a link with the satellite, the statistical parameters that characterize the rainrate process at the terminal site, the length of the propagation path within the potential rain region, and its projected length onto the local horizontal. The IBM PC version of LeRC-SLAM (LEW-14979) is written in Microsoft QuickBASIC for an IBM PC compatible computer with a monitor and printer capable of supporting an 80-column format. The IBM PC version is available on a 5.25 inch MS-DOS format diskette. The program requires about 30K RAM. The source code and executable are included. The Macintosh version of LeRC-SLAM (LEW-14977) is written in Microsoft Basic, Binary (b) v2.00 for Macintosh II series computers running MacOS. This version requires 400K RAM and is available on a 3.5 inch 800K Macintosh format diskette, which includes source code only. The Macintosh version was developed in 1987 and the IBM PC version was developed in 1989. IBM PC is a trademark of International Business Machines. MS-DOS is a registered trademark of Microsoft Corporation. Macintosh is a registered trademark of Apple Computer, Inc.

Multi drop bus controller for IBM PC/AT

International Nuclear Information System (INIS)

Bardik, Yu.I.; Kalistratov, E.N.; Matyushin, A.A.; Obukhov, G.A.; Trofimov, N.N.

1993-01-01

The module PC-AT-PBC gives a possibility to create a working place based on the computer IBM PC/AT for testing of hardware which is compatible with the multi drop bus. The KP1830BE31 micro program change turns the module into timing generator for power supply controllers of the UNK correction system. The structure of the module, functional parts, library functions and two application programs have been described. 4 refs., 9 figs

Design of multichannel counting system-2 for IBM PC and compatibles

International Nuclear Information System (INIS)

Ahmad, Z.; Qamer, R.; Mushtaq, N.

2001-04-01

A multichannel, Counting System 2 (MCCS-2) data acquisition plug-in card for the IBM ISA, MCA and EISA bus architecture has been designed and developed for acquisition of pulsed signal. The card features large dynamic range is achieved with the help of 16-bit pulse counters, fast signal acquisition and a self-testing capability in a single slot card. The MCCS-2 (designed by R and D group, CD) is an upgraded version of MCCS-1 [6]. The MCCS-2 consists of a plug-in interface card (MCCS-PC) for IBM PC and compatibles and a BNC terminal module (MCCS-BNC). The MCCS-PC is address selectable and can simultaneous monitoring ten independent SCA inputs. An on board programmable timer provides elapsed time measurement. A menu-driven software program is developed for data acquisition and timer control. (author)

Using IBMs to Investigate Spatially-dependent Processes in Landscape Genetics Theory

Science.gov (United States)

Much of landscape and conservation genetics theory has been derived using non-spatialmathematical models. Here, we use a mechanistic, spatially-explicit, eco-evolutionary IBM to examine the utility of this theoretical framework in landscapes with spatial structure. Our analysis...

Clinical significance of proliferation, apoptosis and senescence of nasopharyngeal cells by the simultaneously blocking EGF, IGF-1 receptors and Bcl-xl genes

International Nuclear Information System (INIS)

Dai, Guodong; Peng, Tao; Zhou, Xuhong; Zhu, Jun; Kong, Zhihua; Ma, Li; Xiong, Zhi; Yuan, Yulin

2013-01-01

Highlight: •Construction of shRNA segments expression vectors is valid by the investigation of RT-PCR for IGF1R, EGFR and Bcl-xl mRNA and protein expression. •Studies have suggested that the vectors in blocking these genes of the growth factor receptors and anti- apoptosis is capable of breaking the balance of tumor growth so that tumor trend apoptosis and senescence. •Simultaneously blocking multiple genes that are abnormally expressed may be more effective in treating cancer cells than silencing a single gene. -- Abstract: Background: In previous work, we constructed short hairpin RNA (shRNA) expression plasmids that targeted human EGF and IGF-1 receptors messenger RNA, respectively, and demonstrated that these vectors could induce apoptosis of human nasopharyngeal cell lines (CNE2) and inhibit ligand-induced pAkt and pErk activation. Method: We have constructed multiple shRNA expression vectors of targeting EGFR, IGF1R and Bcl-xl, which were transfected to the CNE2 cells. The mRNA expression was assessed by RT-PCR. The growth of the cells, cell cycle progression, apoptosis of the cells, senescent tumor cells and the proteins of EGFR, IGF1R and Bcl-xl were analyzed by MTT, flow cytometry, cytochemical therapy or Western blot. Results: In group of simultaneously blocking EGFR, IGF1R and Bcl-xl genes, the mRNA of EGFR, IGF1R and Bcl-xl expression was decreased by (66.66 ± 3.42)%, (73.97 ± 2.83)% and (64.79 ± 2.83)%, and the protein expressions was diminished to (67.69 ± 4.02)%, (74.32 ± 2.30)%, and (60.00 ± 3.34)%, respectively. Meanwhile, the cell apoptosis increased by 65.32 ± 0.18%, 65.16 ± 0.25% and 55.47 ± 0.45%, and senescent cells increased by 1.42 ± 0.15%, 2.26 ± 0.15% and 3.22 ± 0.15% in the second, third and fourth day cultures, respectively. Conclusions: Simultaneously blocking EGFR, IGF1R and Bcl-xl genes is capable of altering the balance between proliferating versus apoptotic and senescent cells in the favor of both of apoptosis and

Clinical significance of proliferation, apoptosis and senescence of nasopharyngeal cells by the simultaneously blocking EGF, IGF-1 receptors and Bcl-xl genes

Energy Technology Data Exchange (ETDEWEB)

Dai, Guodong [Anatomy and Embryology, Wuhan University School of Medicine, Wuhan, Hubei 430071 (China); Peng, Tao; Zhou, Xuhong [Department of Otolaryngology-Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071 (China); Zhu, Jun; Kong, Zhihua; Ma, Li; Xiong, Zhi [Anatomy and Embryology, Wuhan University School of Medicine, Wuhan, Hubei 430071 (China); Yuan, Yulin, E-mail: yuanyulin19620120@126.com [Anatomy and Embryology, Wuhan University School of Medicine, Wuhan, Hubei 430071 (China)

2013-11-01

Highlight: •Construction of shRNA segments expression vectors is valid by the investigation of RT-PCR for IGF1R, EGFR and Bcl-xl mRNA and protein expression. •Studies have suggested that the vectors in blocking these genes of the growth factor receptors and anti- apoptosis is capable of breaking the balance of tumor growth so that tumor trend apoptosis and senescence. •Simultaneously blocking multiple genes that are abnormally expressed may be more effective in treating cancer cells than silencing a single gene. -- Abstract: Background: In previous work, we constructed short hairpin RNA (shRNA) expression plasmids that targeted human EGF and IGF-1 receptors messenger RNA, respectively, and demonstrated that these vectors could induce apoptosis of human nasopharyngeal cell lines (CNE2) and inhibit ligand-induced pAkt and pErk activation. Method: We have constructed multiple shRNA expression vectors of targeting EGFR, IGF1R and Bcl-xl, which were transfected to the CNE2 cells. The mRNA expression was assessed by RT-PCR. The growth of the cells, cell cycle progression, apoptosis of the cells, senescent tumor cells and the proteins of EGFR, IGF1R and Bcl-xl were analyzed by MTT, flow cytometry, cytochemical therapy or Western blot. Results: In group of simultaneously blocking EGFR, IGF1R and Bcl-xl genes, the mRNA of EGFR, IGF1R and Bcl-xl expression was decreased by (66.66 ± 3.42)%, (73.97 ± 2.83)% and (64.79 ± 2.83)%, and the protein expressions was diminished to (67.69 ± 4.02)%, (74.32 ± 2.30)%, and (60.00 ± 3.34)%, respectively. Meanwhile, the cell apoptosis increased by 65.32 ± 0.18%, 65.16 ± 0.25% and 55.47 ± 0.45%, and senescent cells increased by 1.42 ± 0.15%, 2.26 ± 0.15% and 3.22 ± 0.15% in the second, third and fourth day cultures, respectively. Conclusions: Simultaneously blocking EGFR, IGF1R and Bcl-xl genes is capable of altering the balance between proliferating versus apoptotic and senescent cells in the favor of both of apoptosis and

Configuration control plan for the ports NCS IBM RS/6000

International Nuclear Information System (INIS)

Brown, A.S.

1996-01-01

This document describes the actions and responsibilities for maintaining the quality and integrity of the NS software resident on the IBM RS/6000 workstation managed by the Nuclear Criticality Safety group at the Portsmouth Gaseous Diffusion Plant. This document does not address the validation of NS software packages for the RS/6000

International Business Machines (IBM) Corporation Interim Agreement EPA Case No. 08-0113-00

Science.gov (United States)

On March 27, 2008, the United States Environmental Protection Agency (EPA), suspended International Business Machines (IBM) from receiving Federal Contracts, approved subcontracts, assistance, loans and other benefits.

A Microsoft-Excel-based tool for running and critically appraising network meta-analyses--an overview and application of NetMetaXL.

Science.gov (United States)

Brown, Stephen; Hutton, Brian; Clifford, Tammy; Coyle, Doug; Grima, Daniel; Wells, George; Cameron, Chris

2014-09-29

The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analyses. However, the learning curve for WinBUGS can be daunting, especially for new users. Furthermore, critical appraisal of network meta-analyses conducted in WinBUGS can be challenging given its limited data manipulation capabilities and the fact that generation of graphical output from network meta-analyses often relies on different software packages than the analyses themselves. We developed a freely available Microsoft-Excel-based tool called NetMetaXL, programmed in Visual Basic for Applications, which provides an interface for conducting a Bayesian network meta-analysis using WinBUGS from within Microsoft Excel. . This tool allows the user to easily prepare and enter data, set model assumptions, and run the network meta-analysis, with results being automatically displayed in an Excel spreadsheet. It also contains macros that use NetMetaXL's interface to generate evidence network diagrams, forest plots, league tables of pairwise comparisons, probability plots (rankograms), and inconsistency plots within Microsoft Excel. All figures generated are publication quality, thereby increasing the efficiency of knowledge transfer and manuscript preparation. We demonstrate the application of NetMetaXL using data from a network meta-analysis published previously which compares combined resynchronization and implantable defibrillator therapy in left ventricular dysfunction. We replicate results from the previous publication while demonstrating result summaries generated by the software. Use of the freely available NetMetaXL successfully demonstrated its ability to make running network meta-analyses more accessible to novice WinBUGS users by allowing analyses to be conducted entirely within Microsoft Excel. NetMetaXL also allows for more efficient and transparent

An IBM 370 assembly language program verifier

Science.gov (United States)

Maurer, W. D.

1977-01-01

The paper describes a program written in SNOBOL which verifies the correctness of programs written in assembly language for the IBM 360 and 370 series of computers. The motivation for using assembly language as a source language for a program verifier was the realization that many errors in programs are caused by misunderstanding or ignorance of the characteristics of specific computers. The proof of correctness of a program written in assembly language must take these characteristics into account. The program has been compiled and is currently running at the Center for Academic and Administrative Computing of The George Washington University.

Direct comparison of the FibroScan XL and M probes for assessment of liver fibrosis in obese and nonobese patients

Directory of Open Access Journals (Sweden)

Durango E

2013-07-01

Full Text Available Esteban Durango,1,* Christian Dietrich,1,* Helmut Karl Seitz,1 Cornelia Ursula Kunz,2 Gilles T Pomier-Layrargues,3 Andres Duarte-Rojo,4 Melanie Beaton,5 Magdy Elkhashab,6 Robert P Myers,7 Sebastian Mueller1,3 1Department of Medicine and Center for Alcohol Research, Liver Disease and Nutrition, Salem Medical Center, 2Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany; 3Liver Unit, Centre Hospitalier de l'Université de Montréal, Hôpital Saint-Luc, Montréal, Quebec, 4Toronto Western Hospital Liver Centre, Toronto, Ontario; 5Multi-Organ Transplant Unit, University of Western Ontario, London, Ontario; 6The Toronto Liver Centre, Toronto, Ontario; 7Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada *These authors contributed equally to this researchBackground: A novel Fibroscan XL probe has recently been introduced and validated for obese patients, and has a diagnostic accuracy comparable with that of the standard M probe. The aim of this study was to analyze and understand the differences between these two probes in nonobese patients, to identify underlying causes for these differences, and to develop a practical algorithm to translate results for the XL probe to those for the M probe.Methods and results: Both probes were directly compared first in copolymer phantoms of varying stiffness (4.8, 11, and 40 kPa and then in 371 obese and nonobese patients (body mass index, range 17.2–72.4 from German (n = 129 and Canadian (n = 242 centers. Liver stiffness values for both probes correlated better in phantoms than in patients (r = 0.98 versus 0.82, P 10 kPa for F0, F1–2, F3, and F4 fibrosis, respectively significantly improved agreement between the two probes from r = 0.655 to 0.679.Conclusion: Liver stiffness can be measured in significantly more obese and nonobese patients using the XL probe than the M probe. However, the XL

Programming the Linpack Benchmark for the IBM PowerXCell 8i Processor

Directory of Open Access Journals (Sweden)

Michael Kistler

2009-01-01

Full Text Available In this paper we present the design and implementation of the Linpack benchmark for the IBM BladeCenter QS22, which incorporates two IBM PowerXCell 8i1 processors. The PowerXCell 8i is a new implementation of the Cell Broadband Engine™2 architecture and contains a set of special-purpose processing cores known as Synergistic Processing Elements (SPEs. The SPEs can be used as computational accelerators to augment the main PowerPC processor. The added computational capability of the SPEs results in a peak double precision floating point capability of 108.8 GFLOPS. We explain how we modified the standard open source implementation of Linpack to accelerate key computational kernels using the SPEs of the PowerXCell 8i processors. We describe in detail the implementation and performance of the computational kernels and also explain how we employed the SPEs for high-speed data movement and reformatting. The result of these modifications is a Linpack benchmark optimized for the IBM PowerXCell 8i processor that achieves 170.7 GFLOPS on a BladeCenter QS22 with 32 GB of DDR2 SDRAM memory. Our implementation of Linpack also supports clusters of QS22s, and was used to achieve a result of 11.1 TFLOPS on a cluster of 84 QS22 blades. We compare our results on a single BladeCenter QS22 with the base Linpack implementation without SPE acceleration to illustrate the benefits of our optimizations.

Integrated Tiger Series of electron/photon Monte Carlo transport codes: a user's guide for use on IBM mainframes

International Nuclear Information System (INIS)

Kirk, B.L.

1985-12-01

The ITS (Integrated Tiger Series) Monte Carlo code package developed at Sandia National Laboratories and distributed as CCC-467/ITS by the Radiation Shielding Information Center (RSIC) at Oak Ridge National Laboratory (ORNL) consists of eight codes - the standard codes, TIGER, CYLTRAN, ACCEPT; the P-codes, TIGERP, CYLTRANP, ACCEPTP; and the M-codes ACCEPTM, CYLTRANM. The codes have been adapted to run on the IBM 3081, VAX 11/780, CDC-7600, and Cray 1 with the use of the update emulator UPEML. This manual should serve as a guide to a user running the codes on IBM computers having 370 architecture. The cases listed were tested on the IBM 3033, under the MVS operating system using the VS Fortran Level 1.3.1 compiler

User's manual for levelized power generation cost using an IBM PC

International Nuclear Information System (INIS)

Fuller, L.C.

1985-06-01

Programs for the estimation of levelized electric power generation costs using the BASIC interpreter on an IBM PC are described. Procedures for light-water reactor plants and coal-fired plants include capital investment cost, operation and maintenance cost, fuel cycle cost, nuclear decommissioning cost, and levelized total generation cost

Multifunction input-output board for the IBM AT/XT (Lab-Master)

Energy Technology Data Exchange (ETDEWEB)

Pilyar, A V

1996-12-31

Multifunction input-output board for the IBM PC AT/XT is described. It consists of a CMOS analog input multiplexer, programmable amplifier, a fast 12-bit ADC, four 10-bit DAC and two 8-bit digital input-output registers. Specifications of analog input and output are given. 6 refs.

Centro de cálculo IBM - Francfort (Alemania Federal

Directory of Open Access Journals (Sweden)

Apel, Beckert, Becker, Arquitectos

1972-03-01

Full Text Available This centre comprises a tall building, of approximately square cross section, and a 10 m high rectangular block. The first one houses the offices, and the second contains an IBM computer and accessories. The structure is of reinforced concrete for the vertical members, and ribbed flooring slabs for the horizontal ones. The external enclosing medium consists of precast concrete elements, and large glazed surfaces. The are features of ornamental significance, such as the indoor helicoidal stairs of unfaced concrete, and the slab covered square, with its garden and artificial lake areas. Parking space is provided in the basements.El complejo se compone de: — un rascacielos con planta sensiblemente cuadrada y 38 m de altura, y — un bloque rectangular, más bajo, de 9,90 m de alto. El primero alberga las oficinas, y el segundo se destina a cubrir todas las exigencias que se derivan del funcionamiento de un ordenador IBM. Su estructura, a base de núcleos verticales de hormigón armado, forjados nervados y cerramientos compuestos de piezas de hormigón, prefabricadas, con grandes zonas acristaladas. Hay motivos ornamentales, como la escalera helicoidal interior, de hormigón visto, y la plaza enlosada, con estanques y jardineras. Aparcamiento en el sótano.

Can Bcl-XL expression predict the radio sensitivity of Bilharzial-related squamous bladder carcinoma? a prospective comparative study

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Kamel Nermen A

2011-01-01

Full Text Available Abstract Background Local pelvic recurrence after radical cystectomy for muscle invasive bilharzial related squamous cell carcinoma accounts for 75% of treatment failures even in organ confined tumors. Despite the proven value of lymphadenectomy, up to 60% of patients undergoing cystectomy do not have it. These factors are in favor of adjuvant radiotherapy reevaluation. objectives: to evaluate the effect of adjuvant radiotherapy on disease free survival in muscle invasive bilharzial related squamous cell carcinoma of the urinary bladder and to test the predictability of radio-sensitivity using the anti apoptotic protein Bcl-XL. Methods The study prospectively included 71 patients, (47 males, 24 females with muscle invasive bilharzial related squamous cell carcinoma of the bladder (Stage pT2a-T3N0-N3M0 who underwent radical cystectomy in Assiut university hospitals between January 2005 and December 2006. Thirty eight patients received adjuvant radiotherapy to the pelvis in the dose of 50Gy/25 fractions/5 weeks (Group 1, while 33 patients did not receive adjuvant radiotherapy (group 2. Immunohistochemical characterization for bcl-xL expression was done. Follow up was done every 3 months for 12 to 36 months with a mean of 16 ± 10 months. All data were analyzed using SPSS version 16. Three years cumulative disease free survival was calculated and adjusted to Bcl-XL expression and side effects of the treatment were recorded. Results The disease free cumulative survival was 48% for group 1 and 29% for group 2 (log rank p value 0.03. The multivariate predictors of tumor recurrence were the positive Bcl-XL expression (odd ratio 41.1, 95% CI 8.4 - 102.3, p Conclusions Adjuvant radiotherapy for muscle invasive bilharzial related squamous cell carcinoma of the urinary bladder has potential effectiveness and minor side effects. Moreover, Bcl-XL expression is a valuable tool for predicting those who might not respond to this adjuvant treatment.

Butyrate down regulates BCL-XL and sensitizes human fibroblasts to radiation and chemotherapy induced apoptosis

International Nuclear Information System (INIS)

Chung, Diana H.; Ljungman, Mats; Zhang Fenfen; Chen Feng; McLaughlin, William P.

1997-01-01

Purpose/Objective: Butyrate is a short chain fatty acid that has been implicated in the induction of cell cycle arrest, cell differentiation and apoptosis. The purpose of this study was to determine if butyrate treatment sensitizes cells to radiation or chemotherapy induced apoptosis. Materials and Methods: Normal neonatal human diploid fibroblasts were used throughout this study. Apoptosis was scored and quantified using three different methods. First, cell morphology using propidium iodide and fluorescence microscopy was used to qualitatively determine apoptosis and to quantify the percentage of cells undergoing apoptosis. Second, apoptosis induced DNA degradation was scored by quantifying the amount of cells appearing in a sub-G1 peak using fixed and PI-stained cells and flow cytometry. Third, apoptosis-induced DNA degradation was examined by using an assay involving direct lysis of cells in the wells of agarose gels followed by conventional gel electrophoresis. Western blotting was used to quantify the cellular levels of the apoptosis regulators, Bcl-2, Bcl-XL and Bax. Results: Human diploid fibroblasts, which were resistant to radiation induced apoptosis, were found to undergo massive apoptosis when radiation was combined with butyrate treatment. Sensitization was obtained when butyrate was added before or after radiation although the combination of both pre and post-treatment was the most effective. Butyrate was also found to enhance UV light and cisplatin-induced apoptosis. These findings correlated with a reduction of the apoptosis antagonist Bcl-XL. Bcl-XL levels significantly dropped in a time and dose dependent manner. In addition, butyrate effectively blocked UV-induced accumulation of p53. Conclusion: Our results suggest that butyrate may be an attractive agent to use in combination with radiation or chemotherapy to lower the apoptotic threshold of tumor cells, regardless of the p53 status of the tumor cells

Indications for MARS-MRI in Patients Treated With Articular Surface Replacement XL Total Hip Arthroplasty.

Science.gov (United States)

Connelly, James W; Galea, Vincent P; Laaksonen, Inari; Matuszak, Sean J; Madanat, Rami; Muratoglu, Orhun; Malchau, Henrik

2018-04-19

The purpose of this study was to identify which patient and clinical factors are predictive of adverse local tissue reaction (ALTR) and to use these factors to create a highly sensitive algorithm for indicating metal artifact reduction sequence magnetic resonance imaging (MARS-MRI) in Articular Surface Replacement (ASR) XL total hip arthroplasty patients. Our secondary aim was to compare our algorithm to existing national guidelines on when to take MARS-MRI in metal-on-metal total hip arthroplasty patients. The study consisted of 137 patients treated with unilateral ASR XL implants from a prospective, multicenter study. Patients underwent MARS-MRI regardless of clinical presentation at a mean of 6.2 (range, 3.3-10.4) years from surgery. Univariate and multivariate analyses were conducted to determine which variables were predictive of ALTR. Predictors were used to create an algorithm to indicate MARS-MRI. Finally, we compared our algorithm's ability to detect ALTR to existing guidelines. We found a visual analog scale pain score ≥2 (odds ratio [OR] = 2.53; P = .023), high blood cobalt (OR = 1.05; P = .023), and male gender (OR = 2.37; P = .034) to be significant predictors of ALTR presence in our cohort. The resultant algorithm achieved 86.4% sensitivity and 60.2% specificity in detecting ALTR within our cohort. Our algorithm had the highest area under the curve and was the only guideline that was significantly predictive of ALTR (P = .014). Our algorithm including patient-reported pain and sex-specific cutoffs for blood cobalt levels could predict ALTR and indicate MARS-MRI in our cohort of ASR XL metal-on-metal patients with high sensitivity. Level II, diagnostic study. Copyright © 2018 Elsevier Inc. All rights reserved.

A New and Versatile Adjustable Rigidity Actuator with Add-on Locking Mechanism (ARES-XL

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Manuel Cestari

2018-01-01

Full Text Available Adjustable compliant actuators are being designed and implemented in robotic devices because of their ability to minimize large forces due to impacts, to safely interact with the user, and to store and release energy in passive elastic elements. Conceived as a new force-controlled compliant actuator, an adjustable rigidity with embedded sensor and locking mechanism actuator (ARES-XL is presented in this paper. This compliant system is intended to be implemented in a gait exoskeleton for children with neuro muscular diseases (NMDs to exploit the intrinsic dynamics during locomotion. This paper describes the mechanics and initial evaluation of the ARES-XL, a novel variable impedance actuator (VIA that allows the implementation of an add-on locking mechanism to this system, and in combination with its zero stiffness capability and large deflection range, provides this novel joint with improved properties when compared to previous prototypes developed by the authors and other state-of-the-art (SoA devices. The evaluation of the system proves how this design exceeds the main capabilities of a previous prototype as well as providing versatile actuation that could lead to its implementation in multiple joints.

Controlled attenuation parameter using the FibroScan® XL probe for quantification of hepatic steatosis for non-alcoholic fatty liver disease in an Asian population.

Science.gov (United States)

Chan, Wah-Kheong; Nik Mustapha, Nik Raihan; Wong, Grace Lai-Hung; Wong, Vincent Wai-Sun; Mahadeva, Sanjiv

2017-02-01

The FibroScan® XL probe reduces failure of liver stiffness measurement (LSM) and unreliable results in obese patients. The objective of this article is to evaluate the accuracy of controlled attenuation parameter (CAP) obtained using the XL probe for the estimation of hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD). Adult NAFLD patients with a liver biopsy within six months were included and were examined with the FibroScan® M and XL probes. Histopathological findings were reported according to the Non-Alcoholic Steatohepatitis Clinical Research Network Scoring System. Participants who did not have fatty liver on ultrasonography were recruited as controls. A total of 57 NAFLD patients and 22 controls were included. The mean age of the NAFLD patients and controls was 50.1 ± 10.4 years and 20.2 ± 1.3 years, respectively ( p  = 0.000). The mean body mass index was 30.2 ± 5.0 kg per m 2 and 20.5 ± 2.4 kg per m 2 , respectively ( p  = 0.000). The distribution of steatosis grades were: S0, 29%; S1, 17%; S2, 35%; S3, 19%. The AUROC for estimation of steatosis grade ≥ S1, S2 and S3 was 0.94, 0.80 and 0.69, respectively, using the M probe, and 0.97, 0.81 and 0.67, respectively, using the XL probe. CAP obtained using the XL probe had similar accuracy as the M probe for the estimation of hepatic steatosis in NAFLD patients.

A Method for Transferring Photoelectric Photometry Data from Apple II+ to IBM PC

Science.gov (United States)

Powell, Harry D.; Miller, James R.; Stephenson, Kipp

1989-06-01

A method is presented for transferring photoelectric photometry data files from an Apple II computer to an IBM PC computer in a form which is compatible with the AAVSO Photoelectric Photometry data collection process.

High Resolution Displays In The Apple Macintosh And IBM PC Environments

Science.gov (United States)

Winegarden, Steven

1989-07-01

High resolution displays are one of the key elements that distinguish user oriented document finishing or publishing stations. A number of factors have been involved in bringing these to the desktop environment. At Sigma Designs we have concentrated on enhancing the capabilites of IBM PCs and compatibles and Apple Macintosh computer systems.

Behavior of solvent-exposed hydrophobic groove in the anti-apoptotic Bcl-XL protein: clues for its ability to bind diverse BH3 ligands from MD simulations.

Directory of Open Access Journals (Sweden)

Dilraj Lama

Full Text Available Bcl-XL is a member of Bcl-2 family of proteins involved in the regulation of intrinsic pathway of apoptosis. Its overexpression in many human cancers makes it an important target for anti-cancer drugs. Bcl-XL interacts with the BH3 domain of several pro-apoptotic Bcl-2 partners. This helical bundle protein has a pronounced hydrophobic groove which acts as a binding region for the BH3 domains. Eight independent molecular dynamics simulations of the apo/holo forms of Bcl-XL were carried out to investigate the behavior of solvent-exposed hydrophobic groove. The simulations used either a twin-range cut-off or particle mesh Ewald (PME scheme to treat long-range interactions. Destabilization of the BH3 domain-containing helix H2 was observed in all four twin-range cut-off simulations. Most of the other major helices remained stable. The unwinding of H2 can be related to the ability of Bcl-XL to bind diverse BH3 ligands. The loss of helical character can also be linked to the formation of homo- or hetero-dimers in Bcl-2 proteins. Several experimental studies have suggested that exposure of BH3 domain is a crucial event before they form dimers. Thus unwinding of H2 seems to be functionally very important. The four PME simulations, however, revealed a stable helix H2. It is possible that the H2 unfolding might occur in PME simulations at longer time scales. Hydrophobic residues in the hydrophobic groove are involved in stable interactions among themselves. The solvent accessible surface areas of bulky hydrophobic residues in the groove are significantly buried by the loop LB connecting the helix H2 and subsequent helix. These observations help to understand how the hydrophobic patch in Bcl-XL remains stable in the solvent-exposed state. We suggest that both the destabilization of helix H2 and the conformational heterogeneity of loop LB are important factors for binding of diverse ligands in the hydrophobic groove of Bcl-XL.

Comparison of the cardiovascular effects of tamsulosin oral controlled absorption system (OCAS) and alfuzosin prolonged release (XL)

NARCIS (Netherlands)

Michel, Martin C.; Chapple, Christopher R.

2006-01-01

OBJECTIVE: The cardiovascular (CV) effects of tamsulosin oral controlled absorption system (OCAS) 0.4 mg were compared with those of alfuzosin prolonged release (XL) 10 mg. METHODS: Two single-dose, crossover studies were performed. In study 1, CV alpha1-adrenoceptor antagonism was assessed by

Present status and future directions of the Mayo/IBM PACS project

Science.gov (United States)

Morin, Richard L.; Forbes, Glenn S.; Gehring, Dale G.; Salutz, James R.; Pavlicek, William

1991-07-01

This joint project began in 1988 and was motivated by the need to develop an alternative to the archival process in place at that time (magnetic tape) for magnetic resonance imaging and neurological computed tomography. In addition, this project was felt to be an important step in gaining the necessary clinical experience for the future implementation of various aspects of electronic imaging. The initial phase of the project was conceived and developed to prove the concept, test the fundamental components, and produce performance measurements for future work. The key functions of this phase centered on attachment of imaging equipment (GE Signa) and archival processes using a non-dedicated (institutionally supplied) local area network (LAN). Attachment of imaging equipment to the LAN was performed using commercially available devices (Ethernet, PS/2, Token Ring). Image data were converted to ACR/NEMA format with retention of the vendor specific header information. Performance measurements were encouraging and led to the design of following projects. The second phase has recently been concluded. The major features of this phase have been to greatly expand the network, put the network into clinical use, establish an efficient and useful viewing station, include diagnostic reports in the archive data, provide wide area network (WAN) capability via ISDN, and establish two-way real-time video between remote sites. This phase has heightened both departmental and institutional thought regarding various issues raised by electronic imaging. Much discussion regarding both present as well as future archival processes has occurred. The use of institutional LAN resources has proven to be adequate for the archival function examined thus far. Experiments to date have shown that use of dedicated resources will be necessary for retrieval activities at even a basic level. This report presents an overview of the background present status and future directions of the project.

Low-cost general purpose spectral display unit using an IBM PC

International Nuclear Information System (INIS)

Robinson, S.L.

1985-10-01

Many physics experiments require acquisition and analysis of spectral data. commercial minicomputer-based multichannel analyzers collect detected counts at various energies, create a histogram of the counts in memory, and display the resultant spectra. They acquire data and provide the user-to-display interface. The system discussed separates functions into the three modular components of data acquisition, storage, and display. This decoupling of functions allows the experimenter to use any number of detectors for data collection before forwarding up to 64 spectra to the display unit, thereby increasing data throughput over that available with commercial systems. An IBM PC was chosen for the low-cost, general purpose display unit. Up to four spectra may be displayed simultaneously in different colors. The histogram saves 1024 channels per detector, 640 of which may be distinctly displayed per spectra. The IEEE-488 standard provides the data path between the IBM PC and the data collection unit. Data is sent to the PC under interrupt control, using direct memory access. Display manipulations available via keyboard are also discussed

Study on ground state energy band of even 114-124Cd isotopes under the framework of interacting boson model (IBM-1)

International Nuclear Information System (INIS)

Hossain, I.; Abdullah, Hewa Y.; Ahmed, I.M.; Saeed, M.A.; Ahmad, S.T.

2012-01-01

In this research, the ground state gamma ray bands of even 114-124 Cd isotopes are calculated using interacting boson model (IBM-1). The theoretical energy levels for Z = 48, N = 66–76 up to spin-parity 8 + have been obtained by using PHINT computer program. The values of the parameters in the IBM-1 Hamiltonian yield the best fit to the experimental energy spectrum. The calculated results of the ground state energy band are compared to the previous experimental results and the obtained theoretical calculations in IBM-1 are in good agreement with the experimental energy level. (author)

[Behavior in the forced-swimming test and expression of BDNF and Bcl-xl genes in the rat brain].

Science.gov (United States)

Berezova, I V; Shishkina, G T; Kalinina, T S; Dygalo, N N

2011-01-01

A single exposure of rats to the forced-swimming stress decreased BDNF mRNA levels in the cortex and increased Bcl-xl gene expression in the hippocampus and amygdala 24 h after the stress. The animals demonstrated a depressive-like behavior and elevated blood corticosterone level. There was a significant negative correlation between BDNF mRNA level in the cortex and immobility time during swimming. Repeated exposure to swimming stress caused the elevation of the hippocampal BDNF mRNA level assessed 24 h after the second swimming session. The data suggest that stress-induced down-regulation of cortical BDNF gene expression and behavioral despair in the forced-swimming test may be interrelated. The increase in the BDNF and Bcl-xl mRNA levels may contribute to the mechanisms protecting the brain against negative effects of stress.

F-16XL Ship #2 Laminar Flow Glove mounting

Science.gov (United States)

1995-01-01

NASA's two-seat F-16XL research aircraft is shown in the modification hangar at NASA's Dryden Flight Research Center, Edwards, California, during installation of a titanium 'glove' on the upper surface of its modified left wing. The aircraft subsequently carried out a 13-month-long, 45-flight research program which investigated drawing off a small part of the boundary-layer air in order to provide laminar--or smooth--flow over a major portion of a wing flying at supersonic speeds. A turbo-compressor in the aircraft's fuselage provided suction to draw air through more than 10 million tiny laser-drilled holes in the glove via a manifold system employing 20 valves. Data obtained during the program could assist designers of future aircraft in developing a more efficient high-speed civil transport.

Transfer of numeric ASCII data files between Apple and IBM personal computers.

Science.gov (United States)

Allan, R W; Bermejo, R; Houben, D

1986-01-01

Listings for programs designed to transfer numeric ASCII data files between Apple and IBM personal computers are provided with accompanying descriptions of how the software operates. Details of the hardware used are also given. The programs may be easily adapted for transferring data between other microcomputers.

PUBG; purex solvent extraction process model. [IBM3033; CDC CYBER175; FORTRAN IV

Energy Technology Data Exchange (ETDEWEB)

Geldard, J.F.; Beyerlein, A.L.

PUBG is a chemical model of the Purex solvent extraction system, by which plutonium and uranium are recovered from spent nuclear fuel rods. The system comprises a number of mixer-settler banks. This discrete stage structure is the basis of the algorithms used in PUBG. The stages are connected to provide for countercurrent flow of the aqueous and organic phases. PUBG uses the common convention that has the aqueous phase enter at the lowest numbered stage and exit at the highest one; the organic phase flows oppositely. The volumes of the mixers are smaller than those of the settlers. The mixers generate a fine dispersion of one phase in the other. The high interfacial area is intended to provide for rapid mass transfer of the plutonium and uranium from one phase to the other. The separation of this dispersion back into the two phases occurs in the settlers. The species considered by PUBG are Hydrogen (1+), Plutonium (4+), Uranyl Oxide (2+), Plutonium (3+), Nitrate Anion, and reductant in the aqueous phase and Hydrogen (1+), Uranyl Oxide (2+), Plutonium (4+), and TBP (tri-n-butylphosphate) in the organic phase. The reductant used in the Purex process is either Uranium (4+) or HAN (hydroxylamine nitrate).IBM3033;CDC CYBER175; FORTRAN IV; OS/MVS or OS/MVT (IBM3033), NOS 1.3 (CDC CYBER175); The IBM3033 version requires 150K bytes of memory for execution; 62,000 (octal) words are required by the CDC CYBER175 version..

Pengembangan Sistem Informasi Geografis Berbasis Node.JS untuk Pemetaan Mesin dan Tracking Engineer dengan Pemanfaatan Geolocation pada PT IBM Indonesia

Directory of Open Access Journals (Sweden)

RACHMAT FAJRIN

2017-09-01

Full Text Available PT IBM memiliki banyak klien di Indonesia, ini membuat persebaran produk (dalam hal ini mesin atm yang semakin meluas di wilayah Indonesia. Hal ini memicu PT IBM untuk menempatkan engineer dibanyak wilayah untuk memenuhi kebutuhan services dan maintenance. Untuk itu dalam penelitian ini dikembangkan sebuah sistem informasi geografis untuk pemetaan mesin dan tracking engineer dengan pemanfaatan geolocation yang bertujuan untuk menampilkan peta digital beserta lokasi mesin dan engineer di seluruh Indonesia, yang akan memudahkan PT IBM dalam pemberian tugas kepada engineer untuk services dan maintenance ke lokasi mesin terdekat. Sistem ini dibangun menggunakan beberapa software open source yaitu, Node.JS dan Express.JS yang merupakan server-side javascript web platform, Handlebars untuk template engine, MySQL sebagai database storage, Postman yang berfungsi sebagai API (Application Program Interface testing, Google Maps API untuk implementasi peta digital dan juga Firebase Cloud Messaging (FCM untuk platform mengirim notifikasi dari web ke device engineer.Pengembangan Sistem Informasi Geografis Berbasis Node.JS untuk Pemetaan Mesin dan Tracking Engineer dengan Pemanfaatan Geolocation pada PT IBM Indonesia

Nuclear facilities maintenance in the core of management-advanced trend in IBM Maximo asset management applications

International Nuclear Information System (INIS)

Seino, Satoshi; Ujihara, Satoshi; Kikuyama, Kaoru

2009-01-01

European and US plant owners have attached importance to plant maintenance, such as prompt grasp of plant states, implementation of maintenance and planning of maintenance programs, as one of asset management. The US advanced trend was introduced in this feature article through the applications of IBM Maximo Asset Management for nuclear facilities maintenance. World trends of nuclear power and related problems, need of nuclear facilities management, key items for introduction of maintenance management systems, required systems for nuclear maintenance management and introduction of functions of the IBM strategic asset management solution-Maximo were described respectively. (T. Tanaka)

De vis wordt duur(zaam) vervoerd : Openbare eindrapportage AKK-project ACD-03.032

NARCIS (Netherlands)

Snels, J.C.M.A.

2005-01-01

The project `De vis wordt duur(zaam) vervoerd` focuses on the reduction of the amount of driven kilometres in de supply from producers (i.e. Prime Meat and Seafood Partners) to the wholesaler and the distribution routes of the wholesaler (i.e. Deli XL).The reduction can be reached through (1)

Bill Lang's contributions to acoustics at International Business Machines Corporation (IBM), signal processing, international standards, and professionalism in noise control engineering

Science.gov (United States)

Maling, George C.

2005-09-01

Bill Lang joined IBM in the late 1950s with a mandate from Thomas Watson Jr. himself to establish an acoustics program at IBM. Bill created the facilities in Poughkeepsie, developed the local program, and was the leader in having other IBM locations with development and manufacturing responsibilities construct facilities and hire staff under the Interdivisional Liaison Program. He also directed IBMs acoustics technology program. In the mid-1960s, he led an IEEE standards group in Audio and Electroacoustics, and, with the help of James Cooley, Peter Welch, and others, introduced the fast Fourier transform to the acoustics community. He was the convenor of ISO TC 43 SC1 WG6 that began writing the 3740 series of standards in the 1970s. It was his suggestion to promote professionalism in noise control engineering, and, through meetings with Leo Beranek and others, led the founding of INCE/USA in 1971. He was also a leader of the team that founded International INCE in 1974, and he served as president from 1988 until 1999.

76 FR 55155 - Final Environmental Impact Statement for the Proposed Keystone XL Project

Science.gov (United States)

2011-09-06

... border of the U.S. and Canada for the transport of crude oil across the U.S./Canada international... proposed Project that is designed to transport crude oil produced from oil sands in the Western Canadian... security; environmental, cultural, and economic impacts. Before making a decision on the proposed Project...

Research center Juelich to install Germany's most powerful supercomputer new IBM System for science and research will achieve 5.8 trillion computations per second

CERN Multimedia

2002-01-01

"The Research Center Juelich, Germany, and IBM today announced that they have signed a contract for the delivery and installation of a new IBM supercomputer at the Central Institute for Applied Mathematics" (1/2 page).

Measurement system microdensitometer Joyce-Loebl and computer IBM-PC for quantitative evaluation of autoradiograms

International Nuclear Information System (INIS)

Chajecki, T.

1992-01-01

The description of measurement system microdensitometer Joyce-Loebl, computer IBM-PC interface are given in the report. This system gives the possibility to save and processing of autoradiograms quantity data. (author). 2 refs, 14 figs, 2 tabs

ACCI38 XL 2: a useful tool for dose assessment in case of accidental atmospheric releases of radionuclides

International Nuclear Information System (INIS)

Thomassin, A.; Merle-Szeremeta, A.

2002-01-01

In the scope of its assignments in the field of nuclear risks, the French Institute for Radiation protection and Nuclear Safety (IRSN) develops tools to assess the impact of nuclear facilities on their environment and surrounding populations. The code ACCI38 XL 2 is a tool dedicated to the assessment of integrated concentrations in the environment and of dosimetric consequences on man, in case of accidental atmospheric releases of radionuclides (up to 170 radionuclides). This code is widely used by IRSN for studies on accidents, mainly for the analysis of regulatory documents from nuclear operators. The aim of this communication is to present the main features of the model used in the code ACCI38 XL 2, and to give details about the code. After a general presentation of the model, a detailed description of atmospheric dispersion, transfer in the environment and radiological impact is given. Then, some information on parameters and limitations of the model and the code are presented

The Upper- to Middle-Crustal Section of the Alisitos Oceanic Arc, (Baja, Mexico): an Analog of the Izu-Bonin-Marianas (IBM) Arc

Science.gov (United States)

Medynski, S.; Busby, C.; DeBari, S. M.; Morris, R.; Andrews, G. D.; Brown, S. R.; Schmitt, A. K.

2016-12-01

The Rosario segment of the Cretaceous Alisitos arc in Baja California is an outstanding field analog for the Izu-Bonin-Mariana (IBM) arc, because it is structurally intact, unmetamorphosed, and has superior three-dimensional exposures of an upper- to middle-crustal section through an extensional oceanic arc. Previous work1, done in the pre-digital era, used geologic mapping to define two phases of arc evolution, with normal faulting in both phases: (1) extensional oceanic arc, with silicic calderas, and (2) oceanic arc rifting, with widespread diking and dominantly mafic effusions. Our new geochemical data match the extensional zone immediately behind the Izu arc front, and is different from the arc front and rear arc, consistent with geologic relations. Our study is developing a 3D oceanic arc crustal model, with geologic maps draped on Google Earth images, and GPS-located outcrop information linked to new geochemical, geochronological and petrographic data, with the goal of detailing the relationships between plutonic, hypabyssal, and volcanic rocks. This model will be used by scientists as a reference model for past (IBM-1, 2, 3) and proposed IBM (IBM-4) drilling activities. New single-crystal zircon analysis by TIMS supports the interpretation, based on batch SIMS analysis of chemically-abraded zircon1, that the entire upper-middle crustal section accumulated in about 1.5 Myr. Like the IBM, volcanic zircons are very sparse, but zircon chemistry on the plutonic rocks shows trace element compositions that overlap to those measured in IBM volcanic zircons by A. Schmitt (unpublished data). Zircons have U-Pb ages up to 20 Myr older than the eruptive age, suggesting remelting of older parts of the arc, similar to that proposed for IBM (using different evidence). Like IBM, some very old zircons are also present, indicating the presence of old crustal fragments, or sediments derived from them, in the basement. However, our geochemical data show that the magmas are

A low-cost general purpose spectral display unit using an IBM PC

International Nuclear Information System (INIS)

Robinson, S.L.

1986-01-01

Many physics experiments require acquisition and analysis of spectral data. Commercial minicomputer-based multichannel analyzers collect detected counts at various energies, create a histogram of the counts in memory, and display the resultant spectra. They acquire data and provide the user-to-display interface. The system discussed separates functions into the three modular components of data acquisition, storage, and display. This decoupling of functions allows the experimenter to use any number of detectors for data collection before forwarding up to 64 spectra to the display unit, thereby increasing data throughput over that available with commercial systems. An IBM PC was chosen for the low-cost, general purpose display unit. Up to four spectra may be displayed simultaneously in different colors. The histogram saves 1024 channels per detector, 640 of which may be distinctly displayed per spectra. The IEEE-488 standard provides the data path between the IBM PC and the data collection unit. Data is sent to the PC under interrupt control, using direct memory access. Display manipulations available via keyboard are also discussed

CLIPS - C LANGUAGE INTEGRATED PRODUCTION SYSTEM (IBM PC VERSION)

Science.gov (United States)

Riley, G.

1994-01-01

The C Language Integrated Production System, CLIPS, is a shell for developing expert systems. It is designed to allow artificial intelligence research, development, and delivery on conventional computers. The primary design goals for CLIPS are portability, efficiency, and functionality. For these reasons, the program is written in C. CLIPS meets or outperforms most micro- and minicomputer based artificial intelligence tools. CLIPS is a forward chaining rule-based language. The program contains an inference engine and a language syntax that provide a framework for the construction of an expert system. It also includes tools for debugging an application. CLIPS is based on the Rete algorithm, which enables very efficient pattern matching. The collection of conditions and actions to be taken if the conditions are met is constructed into a rule network. As facts are asserted either prior to or during a session, CLIPS pattern-matches the number of fields. Wildcards and variables are supported for both single and multiple fields. CLIPS syntax allows the inclusion of externally defined functions (outside functions which are written in a language other than CLIPS). CLIPS itself can be embedded in a program such that the expert system is available as a simple subroutine call. Advanced features found in CLIPS version 4.3 include an integrated microEMACS editor, the ability to generate C source code from a CLIPS rule base to produce a dedicated executable, binary load and save capabilities for CLIPS rule bases, and the utility program CRSV (Cross-Reference, Style, and Verification) designed to facilitate the development and maintenance of large rule bases. Five machine versions are available. Each machine version includes the source and the executable for that machine. The UNIX version includes the source and binaries for IBM RS/6000, Sun3 series, and Sun4 series computers. The UNIX, DEC VAX, and DEC RISC Workstation versions are line oriented. The PC version and the Macintosh

The USL NASA PC R and D project: General specifications of objectives

Science.gov (United States)

Dominick, Wayne D. (Editor)

1984-01-01

Given here are the general specifications of the objectives of the University of Southwestern Louisiana Data Base Management System (USL/DBMS) NASA PC R and D Project, a project initiated to address future R and D issues related to PC-based processing environments acquired pursuant to the NASA contract work; namely, the IBM PC/XT systems.

The IBM PC as an Online Search Machine--Part 2: Physiology for Searchers.

Science.gov (United States)

Kolner, Stuart J.

1985-01-01

Enumerates "hardware problems" associated with use of the IBM personal computer as an online search machine: purchase of machinery, unpacking of parts, and assembly into a properly functioning computer. Components that allow transformations of computer into a search machine (combination boards, printer, modem) and diagnostics software…

System of image package input and output for neutron radiography based on PC IBM XT/AT; Sistema paketnogo vvoda i vyvoda izobrazhenij dlya nejtronnoj radiografii na baze PEhVM IBM PC XCT/AT

Energy Technology Data Exchange (ETDEWEB)

Avarzad, O; Rikhvitskij, V S

1996-12-31

System of acquisition and analysis of both statistic and dynamic images of neutron radiography includes NM IBM PC XT/AT, super vidicon, telecamera based video detector, color monitor and interface board of image input-output. 2 refs.

National Storage Laboratory: a collaborative research project

Science.gov (United States)

Coyne, Robert A.; Hulen, Harry; Watson, Richard W.

1993-01-01

The grand challenges of science and industry that are driving computing and communications have created corresponding challenges in information storage and retrieval. An industry-led collaborative project has been organized to investigate technology for storage systems that will be the future repositories of national information assets. Industry participants are IBM Federal Systems Company, Ampex Recording Systems Corporation, General Atomics DISCOS Division, IBM ADSTAR, Maximum Strategy Corporation, Network Systems Corporation, and Zitel Corporation. Industry members of the collaborative project are funding their own participation. Lawrence Livermore National Laboratory through its National Energy Research Supercomputer Center (NERSC) will participate in the project as the operational site and provider of applications. The expected result is the creation of a National Storage Laboratory to serve as a prototype and demonstration facility. It is expected that this prototype will represent a significant advance in the technology for distributed storage systems capable of handling gigabyte-class files at gigabit-per-second data rates. Specifically, the collaboration expects to make significant advances in hardware, software, and systems technology in four areas of need, (1) network-attached high performance storage; (2) multiple, dynamic, distributed storage hierarchies; (3) layered access to storage system services; and (4) storage system management.

Pengembangan Sistem Informasi Geografis Berbasis Node.JS untuk Pemetaan Mesin dan Tracking Engineer dengan Pemanfaatan Geolocation pada PT IBM Indonesia

OpenAIRE

Fajrin, Rachmat

2017-01-01

PT IBM memiliki banyak klien di Indonesia, ini membuat persebaran produk (dalam hal ini mesin atm) yang semakin meluas di wilayah Indonesia. Hal ini memicu PT IBM untuk menempatkan engineer dibanyak wilayah untuk memenuhi kebutuhan services dan maintenance. Untuk itu dalam penelitian ini dikembangkan sebuah sistem informasi geografis untuk pemetaan mesin dan tracking engineer dengan pemanfaatan geolocation yang bertujuan untuk menampilkan peta digital beserta lokasi mesin dan engineer di selu...

Hazardous Waste Cleanup: IBM Corporation-TJ Watson Research Center in Yorktown Heights, New York

Science.gov (United States)

IBM Corporation -TJ Watson Research Center is located in southern Yorktown near the boundary separating the Town of Yorktown from the Town of New Castle. The site occupies an area of approximately 217 acres and adjoins land uses are predominantly residenti

IBM ThinkPad radiation testing and recovery during EUROMIR missions

International Nuclear Information System (INIS)

Martignano, M.; Harboe-Sorensen, R.

1995-01-01

This paper presents the results of an experiment, conducted on-board the Russian MIR Space Station during a joint Russian and European mission, EUROMIR '94. A commercially available IBM ThinkPad 750C was evaluated by running a software system which monitored the notebook's behavior and counted the number of single event upsets. The used software system and ground verification tests are also presented. Finally, another software system, able to ruggedize normal personal computers for usage in space, is described

Description of the Rigid Triaxial Deformation at Low Energy in 76Ge with the Proton-Neutron Interacting Model IBM2

International Nuclear Information System (INIS)

Zhang Da-Li; Ding Bin-Gang

2013-01-01

We investigate properties of the low-lying energy states for 76 Ge within the framework of the proton-neutron interacting model IBM2, considering the validity of the Z = 38 subshell closure 88 Sr 50 as a doubly magic core. By introducing the quadrupole interactions among like bosons to the IBM2 Hamiltonian, the energy levels for both the ground state and γ bands are reproduced well. Particularly, the doublet structure of the γ band and the energy staggering signature fit the experimental data correctly. The ratios of B(E2) transition strengths for some states of the γ band, and the g factors of the 2 1 + , 2 2 + states are very close to the experimental data. The calculation result indicates that the nucleus exhibiting rigid triaxial deformation in the low-lying states can be described rather well by the IBM2

A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL

Science.gov (United States)

2014-01-01

Background The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analyses. However, the learning curve for WinBUGS can be daunting, especially for new users. Furthermore, critical appraisal of network meta-analyses conducted in WinBUGS can be challenging given its limited data manipulation capabilities and the fact that generation of graphical output from network meta-analyses often relies on different software packages than the analyses themselves. Methods We developed a freely available Microsoft-Excel-based tool called NetMetaXL, programmed in Visual Basic for Applications, which provides an interface for conducting a Bayesian network meta-analysis using WinBUGS from within Microsoft Excel. . This tool allows the user to easily prepare and enter data, set model assumptions, and run the network meta-analysis, with results being automatically displayed in an Excel spreadsheet. It also contains macros that use NetMetaXL’s interface to generate evidence network diagrams, forest plots, league tables of pairwise comparisons, probability plots (rankograms), and inconsistency plots within Microsoft Excel. All figures generated are publication quality, thereby increasing the efficiency of knowledge transfer and manuscript preparation. Results We demonstrate the application of NetMetaXL using data from a network meta-analysis published previously which compares combined resynchronization and implantable defibrillator therapy in left ventricular dysfunction. We replicate results from the previous publication while demonstrating result summaries generated by the software. Conclusions Use of the freely available NetMetaXL successfully demonstrated its ability to make running network meta-analyses more accessible to novice WinBUGS users by allowing analyses to be conducted entirely within Microsoft Excel. NetMetaXL also allows

The IBM PC as an Online Search Machine. Part 5: Searching through Crosstalk.

Science.gov (United States)

Kolner, Stuart J.

1985-01-01

This last of a five-part series on using the IBM personal computer for online searching highlights a brief review, search process, making the connection, switching between screens and modes, online transaction, capture buffer controls, coping with options, function keys, script files, processing downloaded information, note to TELEX users, and…

User instructions for levelized power generation cost codes using an IBM-type PC

International Nuclear Information System (INIS)

Coen, J.J.; Delene, J.G.

1989-01-01

Programs for the calculation of levelized power generation costs using an IBM or compatible PC are described. Cost calculations for nuclear plants and coal-fired plants include capital investment cost, operation and maintenance cost, fuel cycle cost, decommissioning cost, and total levelized power generation cost. 7 refs., 36 figs., 4 tabs

Comunicação Interna na Era da Colaboração: A IBM Brasil

Directory of Open Access Journals (Sweden)

Ademir Balbino Siqueira Filho

2015-11-01

Full Text Available A transformação em seu modelo de negócio, deixando de ser somente fábrica de computadores os desafios do mundo globalizado e o surgimento de novos valores socioculturais determinaram novos rumos à comunicação interna da International Business Machine (IBM Brasil, empresa subsidiária de uma das maiores empresas de Tecnologia da Informação do mundo – a IBM. Diante de novas estratégias de comunicação interna, meios tradicionais de comunicação dividem o espaço ou, então, dão espaço a novos meios, no qual os colaboradores interagem entre si e com a empresa de uma maneira mais direta, mais rápida e menos formal. 

Demonstration of entanglement assisted invariance on IBM's quantum experience.

Science.gov (United States)

Deffner, Sebastian

2017-11-01

Quantum entanglement is among the most fundamental, yet from classical intuition also most surprising properties of the fully quantum nature of physical reality. We report several experiments performed on IBM's Quantum Experience demonstrating envariance - entanglement assisted invariance. Envariance is a recently discovered symmetry of composite quantum systems, which is at the foundational origin of physics and a quantum phenomenon of pure states. These very easily reproducible and freely accessible experiments on Quantum Experience provide simple tools to study the properties of envariance, and we illustrate this for several cases with "quantum universes" consisting of up to five qubits.

2-D fluid dynamics models for laser driven fusion on IBM 3090 vector multiprocessors

International Nuclear Information System (INIS)

Atzeni, S.

1988-01-01

Fluid-dynamics codes for laser fusion are complex research codes, consisting of many distinct modules and embodying a variety of numerical methods. They are therefore good candidates for testing general purpose advanced computer architectures and the related software. In this paper, after a brief outline of the basic concepts of laser fusion, the implementation of the 2-D laser fusion fluid code DUED on the IBM 3090 VF vector multiprocessors is discussed. Emphasis is put on parallelization, performed by means of IBM Parallel FORTRAN (PF). It is shown how different modules have been optimized by using different features of PF: i) modules based on depth-2 nested loops exploit automatic parallelization; ii) laser light ray tracing is partitioned by scheduling parallel ICCG algorithm (executed in parallel by appropiately synchronized parallel subroutines). Performance results are given for separate modules of the code, as well as for typical complete runs

Desempenho do modelo AcquaNetXL na alocação de água em sistemas de recursos hídricos complexos Performance of the model called AcquaNetXL in the allocation of water in complex water resource systems

Directory of Open Access Journals (Sweden)

André Schardong

2009-01-01

Full Text Available Este artigo apresenta uma ferramenta para análise de sistemas complexos de recursos hídricos denominada AcquaNetXL, que foi desenvolvida no formato de planilha eletrônica, na qual foram incorporados dois modelos de otimização, um linear e outro não linear. Essa ferramenta mantém os conceitos e os atributos de um sistema de suporte a decisão, ou seja, possui as características de estreitar a comunicação entre o usuário e o computador, de facilitar o entendimento, a formulação do problema, a interpretação dos resultados de análise e auxiliar no processo de tomada de decisão, tornando-o mais ordenado, objetivo e transparente. O desempenho do algoritmo utilizado na solução dos problemas de alocação de água foi satisfatório, especialmente para o modelo linear.This article presents a tool for the allocation analysis of complex systems of water resources, called AcquaNetXL, developed in the form of spreadsheet in which a model of linear optimization and another nonlinear were incorporated. The AcquaNetXL keeps the concepts and attributes of a decision support system. In other words, it straightens out the communication between the user and the computer, facilitates the understanding and the formulation of the problem, the interpretation of the results and it also gives a support in the process of decision making, turning it into a clear and organized process. The performance of the algorithms used for solving the problems of water allocation was satisfactory especially for the linear model.

Inzicht in de netwerken op Facebook : Fanpages Analyse van Facebook Fanpages met behulp van de netwerkanalysetool NodeXL

NARCIS (Netherlands)

Sanne Gaastra; Sonja Utz

2013-01-01

Hoe analyseer je het netwerk van fans op je Facebookpagina? En wat zegt dat over de kracht van posts en actoren. In dit whitepaper zetten we uiteen hoe je het gratis programma NodeXL een visuele analyse van je pagina kunt maken. Interessant voor organisaties. Met deze kennis kun je immers gericht

The new ENSDF search system NESSY: IBM/PC nuclear spectroscopy database

International Nuclear Information System (INIS)

Boboshin, I.N.; Varlamov, V.V.

1996-01-01

The universal relational nuclear structure and decay database NESSY (New ENSDF Search SYstem) developed for the IBM/PC and compatible PCs, and based on the international file ENSDF (Evaluated Nuclear Structure Data File), is described. The NESSY provides the possibility of high efficiency processing (the search and retrieval of any kind of physical data) of the information from ENSDF. The principles of the database development are described and examples of applications are presented. (orig.)

An IBM-1620 code for calculation of isotopic composition of irradiated thorium (ISOCOM-2)

International Nuclear Information System (INIS)

Soliman, R.H.; Karchava, G.; Hamouda, I.

1978-01-01

The present work gives a description of an IBM-1620 code to calculate the isotopic composition during the irradiation of a nuclear fuel, which initially contains 232 Th. The numerical results on test calculations are presented. The code has been in operation since 1968

76 FR 21033 - International Business Machines (IBM), Sales and Distribution Business Unit, Global Sales...

Science.gov (United States)

2011-04-14

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,364] International Business Machines (IBM), Sales and Distribution Business Unit, Global Sales Solution Department, Off-Site Teleworker in Centerport, New York; Notice of Affirmative Determination Regarding Application for Reconsideration By application dated November 29, 2011,...

DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines.

Science.gov (United States)

Bing, Lelin; Wu, Junfeng; Zhang, Jianfeng; Chen, Yinghui; Hong, Zhen; Zu, Hengbing

2015-01-01

Previous evidences indicate that androgen is neuroprotective in the brain. However, the underling mechanisms remain to be fully elucidated. Moreover, it is controversial whether dihydrotestosterone (DHT) modulates the expression of apoptosis-related effectors, such as survivin, XIAP, bax, and bcl-xl proteins mediated by the PI3-K/Akt pathway, which contributes to androgen neuroprotection. In this study using a C6 glial cell model, apoptotic cells were detected by flow cytometry. Akt, seladin-1, survivin, XIAP, bcl-xl, and bax protein expression is investigated by Western blot. After amyloid β-protein fragment (Aβ25-35) treatment, apoptotic cells at early (annexin V+, PI-) and late (annexin V+, PI+) stages were significantly increased. Apoptosis at early and late was obviously inhibited in the presence of DHT. The effect of DHT was markedly blocked by PI3-K inhibitor LY294002.To elicit the mechanism of DHT protection, the expression of seladin-1, survivin, XIAP, bax, and bcl-xl protein was determined in C6 cells treated with Aβ25-35, DHT, or LY294002. Aβ25-35 significantly downregulated the expression of seladin-1, survivin, XIAP, bcl-xl protein and upregulated the expression of bax protein. DHT significantly inhibited the expression of bax, seladin-1, survivin, XIAP, and bcl-xl protein induced by Aβ25-35. Further, we found the effect of DHT was significantly inhibited by LY294002. Collectively, in a C6 glial cell model, we firstly found that DHT inhibits Aβ25-35-induced apoptosis by a rapid nongenic PI-3K/Akt activation as well as regulation of seladin-1, survivin, XIAP, bcl-xl, and bax proteins.

Unjuk Kerja Jaringan Seluler 2G dan 3G PT. XL Axiata di Area Jawa Tengah Bagian Utara setelah Proyek Swap dan Modernisasi

Directory of Open Access Journals (Sweden)

Eva Yovita Dwi Utami

2015-04-01

Full Text Available The increasing number of customers and the need for reliable communication require the availability of coverage, sufficient capacity and good quality of mobile communications networks. New BTS implementation is required to cover a wider area with good network quality. However, it often requires high cost and long time to get permission from the government and local residents. Swap and Modernization Project is a project that swap the previous 3G equipment using BTS 3900 Huawei with Ericsson RBS 6000 and modernize the 2G RBS 2000 to RBS 6000 and then carry out parameter settings to optimize the network. In this paper, we report the results of mobile network performance after Swap and Modernization projects had been done in terms of the signal strength improvements, which are showed by Rx Level, RSCP and CDD Dump parameters. The study was conducted in PT XL Axiata Northern Areas of Central Java with D5 cluster as a sample. The results show improvement of Rx Level that increased by 89.93 %, and RSCP value increased by 58.36 %. The swap and modernization of the BTS and parameter settings are able to improve CDD Dump parameters. These improvements are able to expand the coverage area of cluster D5 sites.

Approximate Quantum Adders with Genetic Algorithms: An IBM Quantum Experience

Directory of Open Access Journals (Sweden)

Li Rui

2017-07-01

Full Text Available It has been proven that quantum adders are forbidden by the laws of quantum mechanics. We analyze theoretical proposals for the implementation of approximate quantum adders and optimize them by means of genetic algorithms, improving previous protocols in terms of efficiency and fidelity. Furthermore, we experimentally realize a suitable approximate quantum adder with the cloud quantum computing facilities provided by IBM Quantum Experience. The development of approximate quantum adders enhances the toolbox of quantum information protocols, paving the way for novel applications in quantum technologies.

Handbook of univariate and multivariate data analysis with IBM SPSS

CERN Document Server

Ho, Robert

2013-01-01

Using the same accessible, hands-on approach as its best-selling predecessor, the Handbook of Univariate and Multivariate Data Analysis with IBM SPSS, Second Edition explains how to apply statistical tests to experimental findings, identify the assumptions underlying the tests, and interpret the findings. This second edition now covers more topics and has been updated with the SPSS statistical package for Windows.New to the Second EditionThree new chapters on multiple discriminant analysis, logistic regression, and canonical correlationNew section on how to deal with missing dataCoverage of te

Benchmark Tests on the New IBM RISC System/6000 590 Workstation

Directory of Open Access Journals (Sweden)

Harvey J. Wasserman

1995-01-01

Full Text Available The results of benchmark tests on the superscalar IBM RISC System/6000 Model 590 are presented. A set of well-characterized Fortran benchmarks spanning a range of computational characteristics was used for the study. The data from the 590 system are compared with those from a single-processor CRAY C90 system as well as with other microprocessor-based systems, such as the Digital Equipment Corporation AXP 3000/500X and the Hewlett-Packard HP/735.

Shape coexistence in the neutron-deficient Pt isotopes in the configuration-mixed IBM

International Nuclear Information System (INIS)

Vargas, Carlos E.; Campuzano, Cuauhtemoc; Morales, Irving O.; Frank, Alejandro; Van Isacker, Piet

2008-01-01

The matrix-coherent state approach in the IBM with configuration mixing is used to describe the geometry of neutron-deficient Pt isotopes. Employing a parameter set for all isotopes determined previously, it is found that the lowest minimum goes from spherical to oblate and finally acquires a prolate shape when approaching the mid-shell Pt isotopes

The study of structure in 224–234 thorium nuclei within the framework IBM

Directory of Open Access Journals (Sweden)

Lee Su Youn

2017-01-01

Full Text Available An investigation has been made of the behaviour of nuclear structure as a function of an increase in neutron number from 224Th to 234Th. Thorium of mass number 234 is a typical rotor nucleus that can be explained by the SU(3 limit of the interacting boson model(IBM in the algebraic nuclear model. Furthermore, 224−232Th lie on the path of the symmetry-breaking phase transition. Moreover, the nuclear structure of 224Th can be explained using X(5 symmetry. However, as 226−230Th nuclei are not fully symmetrical nuclei, they can be represented by adding a perturbed term to express symmetry breaking. Through the following three calculation steps, we identified the tendency of change in nuclear structure. Firstly, the structure of 232Th is described using the matrix elements of the Hamiltonian and the electric quadrupole operator between basis states of the SU(3 limit in IBM. Secondly, the low-lying energy levels and E2 transition ratios corresponding to the observable physical values are calculated by adding a perturbed term with the first-order Casimir operator of the U(5 limit to the SU(3 Hamiltonian in IBM. We compared the results with experimental data of 224−234Th. Lastly, the potential of the Bohr Hamiltonian is represented by a harmonic oscillator, as a result of which the structure of 224−234Th could be expressed in closed form by an approximate separation of variables. The results of these theoretical predictions clarify nuclear structure changes in Thorium nuclei over mass numbers of practical significance.

Cost-benefit study of consumer product take-back programs using IBM's WIT reverse logistics optimization tool

Science.gov (United States)

Veerakamolmal, Pitipong; Lee, Yung-Joon; Fasano, J. P.; Hale, Rhea; Jacques, Mary

2002-02-01

In recent years, there has been increased focus by regulators, manufacturers, and consumers on the issue of product end of life management for electronics. This paper presents an overview of a conceptual study designed to examine the costs and benefits of several different Product Take Back (PTB) scenarios for used electronics equipment. The study utilized a reverse logistics supply chain model to examine the effects of several different factors in PTB programs. The model was done using the IBM supply chain optimization tool known as WIT (Watson Implosion Technology). Using the WIT tool, we were able to determine a theoretical optimal cost scenario for PTB programs. The study was designed to assist IBM internally in determining theoretical optimal Product Take Back program models and determining potential incentives for increasing participation rates.

IBM-PC based data acquisition system for a laser enhanced ionisation spectrometer using a low cost GPIB card

International Nuclear Information System (INIS)

Sampath Kumar, R.; Ravindranath, S.V.G.

1992-01-01

An IBM-PC based data acquisition system has been developed for the existing laser enhanced ionisation spectrometer in the Division. Here the boxcar averager (type SR 250) which integrates the spectrometer output is interfaced to an IBM-PC, converted into a GPIB controller with the help of a locally available GPIB card, (Dynalog Micro Systems make PCL 848) through the GPIB port of the computer interface module (SR 245). The menu driven software developed in BASIC, triggers the scan in the dye laser through its control port, collects data from the spectrometer, plots, displays and stores it on the hard disc for further use. (author). 6 refs., 18 figs., 2 appendixes

Project A+ Elementary Technology Demonstration Schools 1990-91. The First Year.

Science.gov (United States)

Marable, Paula; Frazer, Linda

Project A+ Elementary Technology Demonstration Schools is a program made possible through grants from IBM (International Business Machines Corporation) and Apple, Inc. The primary purpose of the program is to demonstrate the educational effectiveness of technology in accelerating the learning of low achieving at-risk students and enhancing the…

Performance characteristics of the Mayo/IBM PACS

Science.gov (United States)

Persons, Kenneth R.; Gehring, Dale G.; Pavicic, Mark J.; Ding, Yingjai

1991-07-01

The Mayo Clinic and IBM (at Rochester, Minnesota) have jointly developed a picture archiving system for use with Mayo's MRI and Neuro CT imaging modalities. The communications backbone of the PACS is a portion of the Mayo institutional network: a series of 4-Mbps token rings interconnected by bridges and fiber optic extensions. The performance characteristics of this system are important to understand because they affect the response time a PACS user can expect, and the response time for non-PACS users competing for resources on the institutional network. The performance characteristics of each component and the average load levels of the network were measured for various load distributions. These data were used to quantify the response characteristics of the existing system and to tune a model developed by North Dakota State University Department of Computer Science for predicting response times of more complex topologies.

77 FR 66580 - Notice of Availability of the Record of Decision (ROD) for the Gulf Coast Pipeline Project

Science.gov (United States)

2012-11-06

... subordinate its rights, acquired under the Wetland Reserve Program, to allow the Gulf Coast Segment (Gulf.... Department of State (DOS) to build and operate the Keystone XL Project. In the original application, Trans... built in three segments: The approximately 850-mile long ``Steele City'' segment from the U.S. border to...

Letter from Hong Kong: A Report on Chinese Food, Fake Apples, and IBM's Asian Strategy.

Science.gov (United States)

Immel, A. Richard

1984-01-01

Notes that microcomputer use in Hong Kong's small business community does not reflect the growth of its high-tech electronics industry and discusses IBM's influence in Hong Kong and Asia, the counterfeiting of Apple microcomputers and software, and why Apple currently has no recourse. (MBR)

76 FR 54800 - International Business Machines (IBM), Software Group Business Unit, Quality Assurance Group, San...

Science.gov (United States)

2011-09-02

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,554] International Business Machines (IBM), Software Group Business Unit, Quality Assurance Group, San Jose, California; Notice of Negative Determination on Reconsideration On January 21, 2011, the Department of Labor (Department) issued an Affirmative Determination Regarding...

The Challenge '88 Project: Interfacing of Chemical Instruments to Computers.

Science.gov (United States)

Lyons, Jim; Verghese, Manoj

The main part of this project involved using a computer, either an Apple or an IBM, as a chart recorder for the infrared (IR) and nuclear magnetic resonance (NMR) spectrophotometers. The computer "reads" these machines and displays spectra on its monitor. The graphs can then be stored for future reference and manipulation. The program to…

Driving the Power of AIX Performance Tuning on IBM Power

CERN Document Server

Milberg, Ken

2009-01-01

A concise reference for IT professionals, this book goes beyond the rules and contains the best practices and strategies for solid tuning methodology. Tips based on years of experience from an AIX tuning master show specific steps for monitoring and tuning CPU, virtual memory, disk I/O, and network components. Also offering techniques for tuning Oracle and Linux structures that run on an IBM power system-as well as for the new AIX 6.1-this manual discusses what tools are available, how to best use them to collect historical data, and when to analyze trends and results. The only comprehensive,

Materials accounting system for an IBM PC

International Nuclear Information System (INIS)

Bearse, R.C.; Thomas, R.J.; Henslee, S.P.; Jackson, B.G.; Tracy, D.B.; Pace, D.M.

1986-01-01

We have adapted the Los Alamos MASS accounting system for use on an IBM PC/AT at the Fuels Manufacturing Facility (FMF) at Argonne National Laboratory-West (ANL-WEST) in Idaho Falls, Idaho. Cost of hardware and proprietary software was less than $10,000 per station. The system consists of three stations between which accounting information is transferred using floppy disks accompanying special nuclear material shipments. The programs were implemented in dBASEIII and were compiled using the proprietary software CLIPPER. Modifications to the inventory can be posted in just a few minutes, and operator/computer interaction is nearly instantaneous. After the records are built by the user, it takes 4 to 5 seconds to post the results to the database files. A version of this system was specially adapted and is currently in use at the FMF facility at Argonne National Laboratory in Idaho Falls. Initial satisfaction is adequate and software and hardware problems are minimal

MOLECULAR DESIGNER: an interactive program for the display of protein structure on the IBM-PC.

Science.gov (United States)

Hannon, G J; Jentoft, J E

1985-09-01

A BASIC interactive graphics program has been developed for the IBM-PC which utilizes the graphics capabilities of that computer to display and manipulate protein structure from coordinates. Structures may be generated from typed files, or from Brookhaven National Laboratories' Protein Data Bank data tapes. Once displayed, images may be rotated, translated and expanded to any desired size. Figures may be viewed as ball-and-stick or space-filling models. Calculated multiple-point perspective may also be added to the display. Docking manipulations are possible since more than a single figure may be displayed and manipulated simultaneously. Further, stereo images and red/blue three-dimensional images may be generated using the accompanying DESIPLOT program and an HP-7475A plotter. A version of the program is also currently available for the Apple Macintosh. Full implementation on the Macintosh requires 512 K and at least one disk drive. Otherwise this version is essentially identical to the IBM-PC version described herein.

Characterization of radiochromic films EBT3 by means of the scanner Vidar dosimetry Pro Red and Epson 10000-XL use; Caracterizacion de films radiocromicos EBT3 mediante el uso de scanner Vidar dosimetry Pro Red y Epson 10000-XL

Energy Technology Data Exchange (ETDEWEB)

Medina, L.; Garrigo, E.; Venencia, D.; Adrada, A.; Filipuzzi, M., E-mail: fisicamedina11@gmail.com [Instituto Privado de Radioterapia, Obispo Oro 423, X5000BFI Cordoba (Argentina)

2014-08-15

The Radiochromic film have become an attractive tool for verification of dose distributions in IMRT because these have high spatial resolution film, are near water equivalent and not require revealed, A critical aspect of the use of these film is used for digitizing scanner The purpose of this paper is to characterize EBT3 using two types of scanner. Were employed The Radiochromic film EBT3, was used photon beam 6 MV generated by a linear accelerator Siemens Primus, he films were irradiated at a dose range between 0 Gy a 9 Gy. The stabilization time after irradiation was 24 hours. The films were digitized with a scanner Epson 10000-XL y el VIDAR Dosimetry Pro Red. We used the software for construction of the calibration curve. The resolution of each dosimetry system was analyzed through the results of the spatial response function by analyzing a step pattern. The Epson scanner is most sensitive to the red channel. This is less than that obtained with the Vidar. The Vidar scanner spatial response profiles disturbs not opposed to Epson analyzed. The calibration curves for both dosimetry systems can be employed. However, the sensitivity and repeatability of the system is better than Red Vidar Epson 10000-XL. (author)

An IBM-1620 code for calculaton of isotopic composition of irradiated uranium (ISOCOM-1)

International Nuclear Information System (INIS)

Soliman, R.H.; Karchava, G.; Hamouda, I.

1974-01-01

The present work gives a description of an IBM-1620 code to calculate the isotopic composition during the irradiation of a nuclear fuel, which initially consists of 235 U and 238 U. The numerical results of test calculations as well as the ET-RR-1 reactor calculations are presented. The code is in operation since 1968

Programming portlets from JSR 168 to IBM WebSphere portal extensions

CERN Document Server

Bernal, Joey; Lynn, Ron; Marston, Cayce; Memon, Usman

2012-01-01

Portals have evolved from simple Web applications with multiple links to an enterprise application delivery platform that serves composite applications. In a world where organizations are gearing up with service-oriented architecture (SOA) strategies and re-working existing apps to fit the Web 2.0 programming model, portals are strategic infrastructure components on every CIO's radar. As companies move toward SOA, portlets become an even hotter topic. Portlets provide the user interface for these services. IBM's unwavering commitment to open standards such as Java Specification Request (JSR 16

Intelligent Bioreactor Management Information System (IBM-IS) for Mitigation of Greenhouse Gas Emissions

Energy Technology Data Exchange (ETDEWEB)

Paul Imhoff; Ramin Yazdani; Don Augenstein; Harold Bentley; Pei Chiu

2010-04-30

Methane is an important contributor to global warming with a total climate forcing estimated to be close to 20% that of carbon dioxide (CO2) over the past two decades. The largest anthropogenic source of methane in the US is 'conventional' landfills, which account for over 30% of anthropogenic emissions. While controlling greenhouse gas emissions must necessarily focus on large CO2 sources, attention to reducing CH4 emissions from landfills can result in significant reductions in greenhouse gas emissions at low cost. For example, the use of 'controlled' or bioreactor landfilling has been estimated to reduce annual US greenhouse emissions by about 15-30 million tons of CO2 carbon (equivalent) at costs between $3-13/ton carbon. In this project we developed or advanced new management approaches, landfill designs, and landfill operating procedures for bioreactor landfills. These advances are needed to address lingering concerns about bioreactor landfills (e.g., efficient collection of increased CH4 generation) in the waste management industry, concerns that hamper bioreactor implementation and the consequent reductions in CH4 emissions. Collectively, the advances described in this report should result in better control of bioreactor landfills and reductions in CH4 emissions. Several advances are important components of an Intelligent Bioreactor Management Information System (IBM-IS).

CLIPS - C LANGUAGE INTEGRATED PRODUCTION SYSTEM (IBM PC VERSION WITH CLIPSITS)

Science.gov (United States)

Riley, , .

1994-01-01

The C Language Integrated Production System, CLIPS, is a shell for developing expert systems. It is designed to allow artificial intelligence research, development, and delivery on conventional computers. The primary design goals for CLIPS are portability, efficiency, and functionality. For these reasons, the program is written in C. CLIPS meets or outperforms most micro- and minicomputer based artificial intelligence tools. CLIPS is a forward chaining rule-based language. The program contains an inference engine and a language syntax that provide a framework for the construction of an expert system. It also includes tools for debugging an application. CLIPS is based on the Rete algorithm, which enables very efficient pattern matching. The collection of conditions and actions to be taken if the conditions are met is constructed into a rule network. As facts are asserted either prior to or during a session, CLIPS pattern-matches the number of fields. Wildcards and variables are supported for both single and multiple fields. CLIPS syntax allows the inclusion of externally defined functions (outside functions which are written in a language other than CLIPS). CLIPS itself can be embedded in a program such that the expert system is available as a simple subroutine call. Advanced features found in CLIPS version 4.3 include an integrated microEMACS editor, the ability to generate C source code from a CLIPS rule base to produce a dedicated executable, binary load and save capabilities for CLIPS rule bases, and the utility program CRSV (Cross-Reference, Style, and Verification) designed to facilitate the development and maintenance of large rule bases. Five machine versions are available. Each machine version includes the source and the executable for that machine. The UNIX version includes the source and binaries for IBM RS/6000, Sun3 series, and Sun4 series computers. The UNIX, DEC VAX, and DEC RISC Workstation versions are line oriented. The PC version and the Macintosh

Validation and optimization of the Ion Torrent S5 XL sequencer and Oncomine workflow for BRCA1 and BRCA2 genetic testing.

Science.gov (United States)

Shin, Saeam; Kim, Yoonjung; Chul Oh, Seoung; Yu, Nae; Lee, Seung-Tae; Rak Choi, Jong; Lee, Kyung-A

2017-05-23

In this study, we validated the analytical performance of BRCA1/2 sequencing using Ion Torrent's new bench-top sequencer with amplicon panel with optimized bioinformatics pipelines. Using 43 samples that were previously validated by Illumina's MiSeq platform and/or by Sanger sequencing/multiplex ligation-dependent probe amplification, we amplified the target with the Oncomine™ BRCA Research Assay and sequenced on Ion Torrent S5 XL (Thermo Fisher Scientific, Waltham, MA, USA). We compared two bioinformatics pipelines for optimal processing of S5 XL sequence data: the Torrent Suite with a plug-in Torrent Variant Caller (Thermo Fisher Scientific), and commercial NextGENe software (Softgenetics, State College, PA, USA). All expected 681 single nucleotide variants, 15 small indels, and three copy number variants were correctly called, except one common variant adjacent to a rare variant on the primer-binding site. The sensitivity, specificity, false positive rate, and accuracy for detection of single nucleotide variant and small indels of S5 XL sequencing were 99.85%, 100%, 0%, and 99.99% for the Torrent Variant Caller and 99.85%, 99.99%, 0.14%, and 99.99% for NextGENe, respectively. The reproducibility of variant calling was 100%, and the precision of variant frequency also showed good performance with coefficients of variation between 0.32 and 5.29%. We obtained highly accurate data through uniform and sufficient coverage depth over all target regions and through optimization of the bioinformatics pipeline. We confirmed that our platform is accurate and practical for diagnostic BRCA1/2 testing in a clinical laboratory.

Shape coexistence in the neutron-deficient Pt isotopes in a configuration mixing IBM

International Nuclear Information System (INIS)

Morales, Irving O.; Vargas, Carlos E.; Frank, Alejandro

2004-01-01

The recently proposed matrix-coherent state approach for configuration mixing IBM is used to describe the evolving geometry of the neutron deficient Pt isotopes. It is found that the Potential Energy Surface (PES) of the Platinum isotopes evolves, when the number of neutrons decreases, from spherical to oblate and then to prolate shapes, in agreement with experimental measurements. Oblate-Prolate shape coexistence is observed in 194,192Pt isotopes

IBM Demonstrates a General-Purpose, High-Performance, High-Availability Cloud-Hosted Data Distribution System With Live GOES-16 Weather Satellite Data

Science.gov (United States)

Snyder, P. L.; Brown, V. W.

2017-12-01

IBM has created a general purpose, data-agnostic solution that provides high performance, low data latency, high availability, scalability, and persistent access to the captured data, regardless of source or type. This capability is hosted on commercially available cloud environments and uses much faster, more efficient, reliable, and secure data transfer protocols than the more typically used FTP. The design incorporates completely redundant data paths at every level, including at the cloud data center level, in order to provide the highest assurance of data availability to the data consumers. IBM has been successful in building and testing a Proof of Concept instance on our IBM Cloud platform to receive and disseminate actual GOES-16 data as it is being downlinked. This solution leverages the inherent benefits of a cloud infrastructure configured and tuned for continuous, stable, high-speed data dissemination to data consumers worldwide at the downlink rate. It also is designed to ingest data from multiple simultaneous sources and disseminate data to multiple consumers. Nearly linear scalability is achieved by adding servers and storage.The IBM Proof of Concept system has been tested with our partners to achieve in excess of 5 Gigabits/second over public internet infrastructure. In tests with live GOES-16 data, the system routinely achieved 2.5 Gigabits/second pass-through to The Weather Company from the University of Wisconsin-Madison SSEC. Simulated data was also transferred from the Cooperative Institute for Climate and Satellites — North Carolina to The Weather Company, as well. The storage node allocated to our Proof of Concept system as tested was sized at 480 Terabytes of RAID protected disk as a worst case sizing to accommodate the data from four GOES-16 class satellites for 30 days in a circular buffer. This shows that an abundance of performance and capacity headroom exists in the IBM design that can be applied to additional missions.

Homomorphic encryption experiments on IBM's cloud quantum computing platform

Science.gov (United States)

Huang, He-Liang; Zhao, You-Wei; Li, Tan; Li, Feng-Guang; Du, Yu-Tao; Fu, Xiang-Qun; Zhang, Shuo; Wang, Xiang; Bao, Wan-Su

2017-02-01

Quantum computing has undergone rapid development in recent years. Owing to limitations on scalability, personal quantum computers still seem slightly unrealistic in the near future. The first practical quantum computer for ordinary users is likely to be on the cloud. However, the adoption of cloud computing is possible only if security is ensured. Homomorphic encryption is a cryptographic protocol that allows computation to be performed on encrypted data without decrypting them, so it is well suited to cloud computing. Here, we first applied homomorphic encryption on IBM's cloud quantum computer platform. In our experiments, we successfully implemented a quantum algorithm for linear equations while protecting our privacy. This demonstration opens a feasible path to the next stage of development of cloud quantum information technology.

Pengaruh Tukul Arwana Sebagai Celebrity Endorser Terhadap Brand Awareness Masyarakat (Studi Kasus Iklan Xl Versi Tukul Arwana)

OpenAIRE

khoiruman, muhammad

2015-01-01

Considerations to be made by marketers in selecting endoser a product other products form the basis of this study. This study aims to determine the effect attributes (performance) endorser of the brand awareness Tukul Arwana in advertising XL. This research is a survey with a sample of the overall amount to 120 respondents. The sampling technique used was purposive sampling. Data collection instruments such as questionnaires and analysis tools used multiple linear regression. Based on the res...

F-16XL Ship #2 in hangar for Laminar Flow Glove mounting

Science.gov (United States)

1995-01-01

NASA's two-seat F-16XL research aircraft is shown in the modification hangar at the Dryden Flight Research Center, Edwards, California, during installation of a titanium 'glove' on the upper surface of its modified left wing. The aircraft subsequently concluded a 13 month-long, 45-flight research program which investigated drawing off a small portion of the boundary-layer air in order to provide laminar -- or smooth -- flow over a major portion of a wing flying at supersonic speeds. A turbo-compressor in the aircraft's fuselage provided suction to draw air through more than 10 million tiny laser-drilled holes in the glove via a manifold system employing 20 valves. Data obtained during the program could assist designers of future high-speed aircraft in developing a more efficient civil transport.

Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis.

Science.gov (United States)

Bakkar, Nadine; Kovalik, Tina; Lorenzini, Ileana; Spangler, Scott; Lacoste, Alix; Sponaugle, Kyle; Ferrante, Philip; Argentinis, Elenee; Sattler, Rita; Bowser, Robert

2018-02-01

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no effective treatments. Numerous RNA-binding proteins (RBPs) have been shown to be altered in ALS, with mutations in 11 RBPs causing familial forms of the disease, and 6 more RBPs showing abnormal expression/distribution in ALS albeit without any known mutations. RBP dysregulation is widely accepted as a contributing factor in ALS pathobiology. There are at least 1542 RBPs in the human genome; therefore, other unidentified RBPs may also be linked to the pathogenesis of ALS. We used IBM Watson ® to sieve through all RBPs in the genome and identify new RBPs linked to ALS (ALS-RBPs). IBM Watson extracted features from published literature to create semantic similarities and identify new connections between entities of interest. IBM Watson analyzed all published abstracts of previously known ALS-RBPs, and applied that text-based knowledge to all RBPs in the genome, ranking them by semantic similarity to the known set. We then validated the Watson top-ten-ranked RBPs at the protein and RNA levels in tissues from ALS and non-neurological disease controls, as well as in patient-derived induced pluripotent stem cells. 5 RBPs previously unlinked to ALS, hnRNPU, Syncrip, RBMS3, Caprin-1 and NUPL2, showed significant alterations in ALS compared to controls. Overall, we successfully used IBM Watson to help identify additional RBPs altered in ALS, highlighting the use of artificial intelligence tools to accelerate scientific discovery in ALS and possibly other complex neurological disorders.

Multivariate methods and forecasting with IBM SPSS statistics

CERN Document Server

Aljandali, Abdulkader

2017-01-01

This is the second of a two-part guide to quantitative analysis using the IBM SPSS Statistics software package; this volume focuses on multivariate statistical methods and advanced forecasting techniques. More often than not, regression models involve more than one independent variable. For example, forecasting methods are commonly applied to aggregates such as inflation rates, unemployment, exchange rates, etc., that have complex relationships with determining variables. This book introduces multivariate regression models and provides examples to help understand theory underpinning the model. The book presents the fundamentals of multivariate regression and then moves on to examine several related techniques that have application in business-orientated fields such as logistic and multinomial regression. Forecasting tools such as the Box-Jenkins approach to time series modeling are introduced, as well as exponential smoothing and naïve techniques. This part also covers hot topics such as Factor Analysis, Dis...

IBM Watson Analytics: Automating Visualization, Descriptive, and Predictive Statistics.

Science.gov (United States)

Hoyt, Robert Eugene; Snider, Dallas; Thompson, Carla; Mantravadi, Sarita

2016-10-11

We live in an era of explosive data generation that will continue to grow and involve all industries. One of the results of this explosion is the need for newer and more efficient data analytics procedures. Traditionally, data analytics required a substantial background in statistics and computer science. In 2015, International Business Machines Corporation (IBM) released the IBM Watson Analytics (IBMWA) software that delivered advanced statistical procedures based on the Statistical Package for the Social Sciences (SPSS). The latest entry of Watson Analytics into the field of analytical software products provides users with enhanced functions that are not available in many existing programs. For example, Watson Analytics automatically analyzes datasets, examines data quality, and determines the optimal statistical approach. Users can request exploratory, predictive, and visual analytics. Using natural language processing (NLP), users are able to submit additional questions for analyses in a quick response format. This analytical package is available free to academic institutions (faculty and students) that plan to use the tools for noncommercial purposes. To report the features of IBMWA and discuss how this software subjectively and objectively compares to other data mining programs. The salient features of the IBMWA program were examined and compared with other common analytical platforms, using validated health datasets. Using a validated dataset, IBMWA delivered similar predictions compared with several commercial and open source data mining software applications. The visual analytics generated by IBMWA were similar to results from programs such as Microsoft Excel and Tableau Software. In addition, assistance with data preprocessing and data exploration was an inherent component of the IBMWA application. Sensitivity and specificity were not included in the IBMWA predictive analytics results, nor were odds ratios, confidence intervals, or a confusion matrix

76 FR 5832 - International Business Machines (IBM), Software Group Business Unit, Optim Data Studio Tools QA...

Science.gov (United States)

2011-02-02

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,554] International Business Machines (IBM), Software Group Business Unit, Optim Data Studio Tools QA, San Jose, CA; Notice of Affirmative Determination Regarding Application for Reconsideration By application dated November 29, 2010, a worker and a state workforce official...

Note on some quasielastic neutron scattering analysis programs on the Rutherford Laboratory IBM 360/195

International Nuclear Information System (INIS)

Richardson, R.M.

1979-12-01

A suite of programs for analysing neutron scattering data from time-of-flight spectrometers has been implemented on the Rutherford Laboratory IBM 360/195 computer system. The programs are intended for near inelastic and quasielastic data and operate by convoluting the measured instrumental resolution function with a model scattering function before fitting to the measured sample scattering law. (author)

SFAP: Scan-Tron Forms Analysis Package for the IBM-PC. User's Guide, Version 2.0.

Science.gov (United States)

Harnisch, Delwyn L.; And Others

The Scan-Tron Forms Analysis Package (SFAP) is a collection of integrated programs that allow an IBM-PC (or compatible) to collect data from a Scan-Tron 1200 forms reader. In addition to the basic data acquisition capability, the SFAP has additional capabilities related to the viewing and formatting of incoming data. When used in combination with…

Ibm BAGI GURU DAN SISWA SMU SETIA BUDI SEMARANG

Directory of Open Access Journals (Sweden)

Adhi Kusmantoro

2016-06-01

Full Text Available Dalam dunia industri ada beberapasistem yang digunakan dalam mengoperasikan sistem pengendalielektromagnetik, antara lain sistem pengoperasian secara manual, semi otomatisdan otomatis.Tujuan pengabdian masyarakat di SMU Setia Budi Semarang adalah untuk memberikan kemampuan penggunaan software EKTS dan menambah pengetahuan atau wawasan teknik pengendali listrik di industri yang sedang berkembang dan banyak dipakai. Metode pelaksanaan kegiatan program Iptek bagi Masyarakat (IbM yang digunakan adalah metode pelatihan yang dibagi dalam tiga tahap, yaitu pelatihan secara teori, pelatihan menggunakan softawre EKTS dan beberapa rancangan pengendali motor listrik, dan tahap evaluasi dalam kegiatan awal sampai dengan akhir. Dalam kegiatan pengabdian masyarakat di SMU Setia Budi Semarang telah dibuat pengendali start stop, pengendali motor berurutan, dan pengendali membalik putaran motor listrik. ?é?á Kata Kunci : EKTS, motor listrik, kontaktor magnet

The influence of central corneal thickness and age on intraocular pressure measured by pneumotonometry, non-contact tonometry, the Tono-Pen XL, and Goldmann applanation tonometry

OpenAIRE

Tonnu, P-A; Ho, T; Newson, T; El Sheikh, A; Sharma, K; White, E; Bunce, C; Garway-Heath, D

2005-01-01

Aims: To evaluate the influence of central corneal thickness (CCT) on intraocular pressure (IOP) measurements made with the Goldmann applanation tonometer (GAT), Tono-Pen XL, ocular blood flow tonograph (OBF), and Canon TX-10 non-contact tonometer (NCT).

Determination of the performance characteristics of a method for the measurement of total phosphorus in groundwater with the PE Optima 3000 XL ICP-AES

NARCIS (Netherlands)

Kohlmeyer U; Breugem PM; Boer JLM de; LAC

1996-01-01

Dit rapport behandelt de prestatiekenmerken van een methode voor de bepaling van totaal-fosfor in grondwater met behulp van ICP-AES met een axiaal plasma (Perkin-Elmer Optima 3000 XL). Met de reeds bestaande methode 'TotP' werden de volgende prestatiekenmerken vastgesteld:

An Amphibious Ship-To-Shore Simulation for Use on an IBM PC (Personal Computer)

Science.gov (United States)

1984-09-01

CA : «< <- j Special ■ *- amphibious ship- an IBM Personal ion of the phy- he logic used analysis, and a DD | JAM 11 1473 COITION...research, for instance, wiL1 be geared toward a technically oriented person who is familiar with computers, programming and the associated logic. A...problem, often vaguely stated by the decision aaker , into precise and operational terms [Ref. Hz p.51]. The analysis begins with specification of the

The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner*

Science.gov (United States)

Kazi, Aslamuzzaman; Sun, Jiazhi; Doi, Kenichiro; Sung, Shen-Shu; Takahashi, Yoshinori; Yin, Hang; Rodriguez, Johanna M.; Becerril, Jorge; Berndt, Norbert; Hamilton, Andrew D.; Wang, Hong-Gang; Sebti, Saïd M.

2011-01-01

A critical hallmark of cancer cell survival is evasion of apoptosis. This is commonly due to overexpression of anti-apoptotic proteins such as Bcl-2, Bcl-XL, and Mcl-1, which bind to the BH3 α-helical domain of pro-apoptotic proteins such as Bax, Bak, Bad, and Bim, and inhibit their function. We designed a BH3 α-helical mimetic BH3-M6 that binds to Bcl-XL and Mcl-1 and prevents their binding to fluorescently labeled Bak- or Bim-BH3 peptides in vitro. Using several approaches, we demonstrate that BH3-M6 is a pan-Bcl-2 antagonist that inhibits the binding of Bcl-XL, Bcl-2, and Mcl-1 to multi-domain Bax or Bak, or BH3-only Bim or Bad in cell-free systems and in intact human cancer cells, freeing up pro-apoptotic proteins to induce apoptosis. BH3-M6 disruption of these protein-protein interactions is associated with cytochrome c release from mitochondria, caspase-3 activation and PARP cleavage. Using caspase inhibitors and Bax and Bak siRNAs, we demonstrate that BH3-M6-induced apoptosis is caspase- and Bax-, but not Bak-dependent. Furthermore, BH3-M6 disrupts Bcl-XL/Bim, Bcl-2/Bim, and Mcl-1/Bim protein-protein interactions and frees up Bim to induce apoptosis in human cancer cells that depend for tumor survival on the neutralization of Bim with Bcl-XL, Bcl-2, or Mcl-1. Finally, BH3-M6 sensitizes cells to apoptosis induced by the proteasome inhibitor CEP-1612. PMID:21148306

A FORTRAN program for an IBM PC compatible computer for calculating kinematical electron diffraction patterns

International Nuclear Information System (INIS)

Skjerpe, P.

1989-01-01

This report describes a computer program which is useful in transmission electron microscopy. The program is written in FORTRAN and calculates kinematical electron diffraction patterns in any zone axis from a given crystal structure. Quite large unit cells, containing up to 2250 atoms, can be handled by the program. The program runs on both the Helcules graphic card and the standard IBM CGA card

NAMMU (Release 6.1) for the IBM RS/6000: installation and running

International Nuclear Information System (INIS)

Cliffe, K.A.

1993-12-01

NAMMU is a software package for modelling groundwater flow and transport in porous media. The package can be used to model steady-state and time-dependent behaviour, including unsaturated flow and the transport of heat and mass. An option is available for modelling radioactive decay and transport of chains of radionuclides. The software is based on an efficient implementation of the finite-element method that provides many options for modelling complex geological strata. This report describes how to install and run Release 6.1 of NAMMU on an IBM RS/6000 using version 6.1.4 of the job submission script. (Author)

Operational experience with open communication in the field of building automation at the IBM center Ehningen; GA-Betriebserfahrung - mit offener Kommunikation im Informatikzentrum Ehningen

Energy Technology Data Exchange (ETDEWEB)

Damnig, A [IBM Deutschland Informationssysteme GmbH, Ehningen bei Boeblingen (Germany)

1995-12-31

In chapter 21 of the anthology about building control the operational experience with open communication in the field of building automation is discussed. The following aspects are discussed: building automation at IBM in Ehningen, the FACN experience, what has been achieved? Energy and operation optimisation. (BWI) [Deutsch] Kapitel 21 des Sammelbandes ueber Building Control ist dem Thema der Betriebserfahrung mit Gebaeudeautomationen mit offener Kommunikation gewidmet. In diesem Zusammenhang werden folgende Themenbereiche angesprochen: Gebaeudeautomation bei IBM in Ehningen, das FACN-Protokoll; Betriebserfahrungen; Was wurde erreicht?; Energie- und Betriebsoptimierungen. (BWI)

Unloading at Cointrin Airport of the IBM 709 computer

CERN Multimedia

CERN PhotoLab

1960-01-01

CERN's first computer, a huge vacuum-tube Ferranti Mercury, was installed in building 2 in 1958. With its 60 microsecond clock cycle, it was a million times slower than today's big computers. The Mercury took 3 months to install and filled a huge room, even so, its computational ability didn't quite match that of a modern pocket calculator. "Mass" storage was provided by four magnetic drums each holding 32K x 20 bits - not enough to hold the data from a single proton-proton collision in the LHC. It was replaced in 1960 by the IBM 709 computer, seen here being unloaded at Cointrin airport. Although it was taken over so quickly by transistor equipped machines, a small part of the Ferranti Mercury remains. The computer's engineers installed a warning bell to signal computing errors - it can still be found mounted on the wall in a corridor of building 2.

The I.B.M. 7090 programmes PERSEUS, ARIADNE, CERBERUS

International Nuclear Information System (INIS)

Green, C.

1964-08-01

An account is given of the programmes PERSEUS, ARIADNE and CERBERUS, written in the Fortran II language for the I.B.M. 7090 computer. PERSEUS calculates multigroup fluxes in a multiregion lattice cell possessing cylindrical symmetry, and which is assumed infinite in the axial direction. Neutron transport is represented by means of first collision probabilities and, at the cell boundary, a 'white' boundary condition is imposed. ARIADNE is a modified version of PERSEUS and calculates multigroup average axial and radial diffusion coefficients in the lattice cell. CERBERUS is also based on PERSEUS and calculates fluxes in an infinite lattice composed of two types of cell arranged in a 'checkerboard' fashion. The two types of cell are assumed infinite axially, cylindrically symmetric and possessing the same maximum radial dimension, but may otherwise be differently constituted. All three programmes have input requirements similar to those of the Winfrith DSN programme. (author)

Authoritarian Decision-Making and Alternative Patterns of Power and Influence: The Mexican IBM Case

Science.gov (United States)

1988-05-01

de Control de Cambios," pp. 1341-1345 and " Decreto Sobre Control de Camblos," pp. 1346-1354. Acceleration of the rate of devaluation was announced in...see " Decreto para la raclonalizaclon de [a industrla automotrlz," Diarlo OfIclal, 15 September 1983 as cited by Bennett and Sharpe, Transnational...v ’ i i I . . . . . . . ". . . . 170 the rules of foreign Investment in the area of computation where IBM wanted to expand Its operations. Programa

Characterization of radiochromic films EBT3 by means of the scanner Vidar dosimetry Pro Red and Epson 10000-XL use

International Nuclear Information System (INIS)

Medina, L.; Garrigo, E.; Venencia, D.; Adrada, A.; Filipuzzi, M.

2014-08-01

The Radiochromic film have become an attractive tool for verification of dose distributions in IMRT because these have high spatial resolution film, are near water equivalent and not require revealed, A critical aspect of the use of these film is used for digitizing scanner The purpose of this paper is to characterize EBT3 using two types of scanner. Were employed The Radiochromic film EBT3, was used photon beam 6 MV generated by a linear accelerator Siemens Primus, he films were irradiated at a dose range between 0 Gy a 9 Gy. The stabilization time after irradiation was 24 hours. The films were digitized with a scanner Epson 10000-XL y el VIDAR Dosimetry Pro Red. We used the software for construction of the calibration curve. The resolution of each dosimetry system was analyzed through the results of the spatial response function by analyzing a step pattern. The Epson scanner is most sensitive to the red channel. This is less than that obtained with the Vidar. The Vidar scanner spatial response profiles disturbs not opposed to Epson analyzed. The calibration curves for both dosimetry systems can be employed. However, the sensitivity and repeatability of the system is better than Red Vidar Epson 10000-XL. (author)

Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells

Energy Technology Data Exchange (ETDEWEB)

Mauro, M.O., E-mail: mari.mauro@hotmail.com [Graduate Program in Biological Sciences (Cell and Molecular Biology), Institute of Biosciences, UNESP, Rio Claro (SP) (Brazil); Sartori, Daniele [General Biology Department, State University of Londrina (UEL), Londrina (Brazil); Oliveira, Rodrigo Juliano [Coordination of Open and Distance Education, Graduate Program in Animal Science, Federal University of Mato Grosso do Sul (UFMS), Campo Grande (MS) (Brazil); Ishii, Priscila Lumi [Graduate Program in Biological Sciences (Cell and Molecular Biology), Institute of Biosciences, UNESP, Rio Claro (SP) (Brazil); Mantovani, Mario Sergio [General Biology Department, State University of Londrina (UEL), Londrina (Brazil); Ribeiro, Lucia Regina [Graduate Program in Biological Sciences (Cell and Molecular Biology), Institute of Biosciences, UNESP, Rio Claro (SP) (Brazil)

2011-10-01

Intestinal cancers are correlated with diet. Thus, determining and understanding nutrient-genome interactions is important. The present work assessed the action of the oligoelement selenium on cell proliferation, cytotoxicity, and in situ apoptosis induction and on the expression CASP9, BCL-XL and APC genes in intestinal adenocarcinoma cells (HT29). HT29 cells were cultured and treated with selenium at concentrations of 5, 50 and 500 ng/mL with or without the damage-inducing agent doxorubicin. These cells were then evaluated for cytotoxicity (MTT), cell proliferation and in situ apoptosis induction. To evaluate gene expression, only the cells treated with 500 ng/mL of selenium were used. RNA was extracted from these cells, and the expressions of CASP9, BCL-XL and APC were analyzed by the RT-PCR method. The GAPDH gene was used as a reference gene. The MTT assay showed that selenium was not cytotoxic at any of the concentrations tested. The cell proliferation assay showed that selenium did not interfere with cell proliferation at the three concentrations tested. In contrast, when the three concentrations were combined with doxorubicin, a significant decrease in the proliferation rate was observed. The apoptosis rate was significantly increased in the selenium (500 ng/mL) and doxorubicin group. CASP9 expression was increased and BCL-XL expression decreased in the selenium (500 ng/mL) and doxorubicin group. APC was significantly increased in the selenium group alone. These results show that selenium increases apoptosis, especially when it is associated with a damage-inducing agent. Also, selenium has an important role in the expression of the APC gene, which is related to cell cycle regulation.

Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells

International Nuclear Information System (INIS)

Mauro, M.O.; Sartori, Daniele; Oliveira, Rodrigo Juliano; Ishii, Priscila Lumi; Mantovani, Mario Sergio; Ribeiro, Lucia Regina

2011-01-01

Intestinal cancers are correlated with diet. Thus, determining and understanding nutrient-genome interactions is important. The present work assessed the action of the oligoelement selenium on cell proliferation, cytotoxicity, and in situ apoptosis induction and on the expression CASP9, BCL-XL and APC genes in intestinal adenocarcinoma cells (HT29). HT29 cells were cultured and treated with selenium at concentrations of 5, 50 and 500 ng/mL with or without the damage-inducing agent doxorubicin. These cells were then evaluated for cytotoxicity (MTT), cell proliferation and in situ apoptosis induction. To evaluate gene expression, only the cells treated with 500 ng/mL of selenium were used. RNA was extracted from these cells, and the expressions of CASP9, BCL-XL and APC were analyzed by the RT-PCR method. The GAPDH gene was used as a reference gene. The MTT assay showed that selenium was not cytotoxic at any of the concentrations tested. The cell proliferation assay showed that selenium did not interfere with cell proliferation at the three concentrations tested. In contrast, when the three concentrations were combined with doxorubicin, a significant decrease in the proliferation rate was observed. The apoptosis rate was significantly increased in the selenium (500 ng/mL) and doxorubicin group. CASP9 expression was increased and BCL-XL expression decreased in the selenium (500 ng/mL) and doxorubicin group. APC was significantly increased in the selenium group alone. These results show that selenium increases apoptosis, especially when it is associated with a damage-inducing agent. Also, selenium has an important role in the expression of the APC gene, which is related to cell cycle regulation.

Determination of Hamiltonian matrix for IBM4 and compare it is self value with shells model

International Nuclear Information System (INIS)

Slyman, S.; Hadad, S.; Souman, H.

2004-01-01

The Hamiltonian is determined using the procedure OAI and the mapping of (IBM4) states into the shell model, which is based on the seniority classification scheme. A boson sub-matrix of the shell model Hamiltonian for the (sd) 4 configuration is constructed, and is proved to produce the same eigenvalues as the shell model Hamiltonian for the corresponding fermion states. (authors)

IbM PENGEMBANGAN POTENSI LOKAL POSDAYA DURIAN JAYA MENUJU DESA WISATA DI KELURAHAN BUBAKAN, KEC. MIJEN, KOTA SEMARANG

Directory of Open Access Journals (Sweden)

Rasiman .

2015-09-01

Full Text Available Abstract ?é?á Based on the data analysis of monograph in Bubakan Village, whichhas various kinds of?é?á potential local resources (e.q:fruits, plants vegetable and cattle, Posdaya Durian Jayaas a partner of IbM, has some potential activities that can be developed?é?á as pioneer of potential local tourist resort intheareaofBubakanvillage. The present activities of the Posdaya are divided into several fields:a.Education;b.Health;c.Entrepreneurship; andd.Environment Care. Those localpotentialresources were still needed serious managerial development in accordance todesign a new local tourist resort. The IbM activities in RW02 Bubakan aimed at 1 making cat fish abon and various food from flourmocaf, 2 conducting a seminar with village officials, community leaders, and the group Posdaya to design a?é?á tourist village. 3 socializing about?é?á nutrients forchildren in Posyandu ?óÔé¼?ôMawar Dua?óÔé¼?Ø. Keyword: local potential resources, Posdaya Durian Jaya, local tourist resort

Comparison of three methods of tonometry in normal subjects: Goldmann applanation tonometer, non-contact airpuff tonometer, and Tono-Pen XL

OpenAIRE

Yilmaz, Ihsan; Altan,Cigdem; Aygit,Ebru Demet; Alagoz,Cengiz; Baz,Okkes; Ahmet,Sibel; Urvasizoglu,Semih; Yaşa,Dilek; Demirok,Ahmet

2014-01-01

Ihsan Yilmaz, Cigdem Altan, Ebru Demet Aygit, Cengiz Alagoz, Okkes Baz, Sibel Ahmet, Semih Urvasizoglu, Dilek Yasa, Ahmet DemirokBeyoglu Eye Training and Research Hospital, Istanbul, TurkeyObjective: We aimed to compare intraocular pressure (IOP) measurements via three different tonometers: the Goldmann applanation tonometer (GAT), the Tono-Pen® XL (TPXL), and a non-contact airpuff tonometer (NCT).Methods: This was a cross-sectional study of 200 eyes from 20...

AXAOTHER XL -- A spreadsheet for determining doses for incidents caused by tornadoes or high-velocity straight winds

International Nuclear Information System (INIS)

Simpkins, A.A.

1996-09-01

AXAOTHER XL is an Excel Spreadsheet used to determine dose to the maximally exposed offsite individual during high-velocity straight winds or tornado conditions. Both individual and population doses may be considered. Potential exposure pathways are inhalation and plume shine. For high-velocity straight winds the spreadsheet has the capability to determine the downwind relative air concentration, however for the tornado conditions, the user must enter the relative air concentration. Theoretical models are discussed and hand calculations are performed to ensure proper application of methodologies. A section has also been included that contains user instructions for the spreadsheet

STAPRE and SCAT2. Statistical pre-equilibrium and optical nuclear model code for Personal Computer IBM/AT

International Nuclear Information System (INIS)

Goulo, V.G.

1988-01-01

This document describes the content of the diskettes with nuclear data production codes SCAT2 and STAPRE and the example data set for implementing and testing of these codes for personal computers IBM/AT. They are available on two diskettes, free fo charge, upon request from the NEA Data Bank, Saclay, France. (author). 4 refs, 1 fig

Agreement among Goldmann applanation tonometer, iCare, and Icare PRO rebound tonometers; non-contact tonometer; and Tonopen XL in healthy elderly subjects.

Science.gov (United States)

Kato, Yoshitake; Nakakura, Shunsuke; Matsuo, Naoko; Yoshitomi, Kayo; Handa, Marina; Tabuchi, Hitoshi; Kiuchi, Yoshiaki

2018-04-01

To evaluate the inter-device agreement among the Goldmann applanation tonometer (GAT), iCare and Icare PRO rebound tonometers, non-contact tonometer (NCT), and Tonopen XL tonometer. Sixty healthy elderly subjects were enrolled. The intraocular pressure (IOP) in each subject's right eye was measured thrice using each of the five tonometers. Intra-device agreement was evaluated by calculating intraclass correlation coefficients (ICCs). Inter-device agreement was evaluated by ICC and Bland-Altman analyses. ICCs for intra-device agreement for each tonometer were >0.8. IOP as measured by iCare (mean ± SD, 11.6 ± 2.5 mmHg) was significantly lower (p tonometers (all ICCs tonometers ranged from 14.94 to 16.47 mmHg. Among the other tonometers, however, the widths of 95% limits of agreement ranged from 7.91 to 9.24 mmHg. There was good inter-device agreement among GAT, rebound tonometers, and NCT. Tonopen XL shows the worst agreement with the other tonometers; therefore, we should pay attention to its' respective IOP. Japan Clinical Trials Register; number: UMIN000011544.

Transient elastography with the XL probe rapidly identifies patients with nonhepatic ascites

Directory of Open Access Journals (Sweden)

Mueller S

2012-05-01

Full Text Available Anna Kohlhaas1, Esteban Durango1, Gunda Millonig1, Cecile Bastard2, Laurent Sandrin2, Mohammad Golriz3, Arianeb Mehrabi3, Markus W Büchler3, Helmut Karl Seitz1, Sebastian Mueller11Department of Medicine and Center for Alcohol Research, Liver Disease and Nutrition, Salem Medical Center, University of Heidelberg, Heidelberg, Germany; 2Department of Research and Development, Echosens, Paris, France; 3Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, GermanyBackground: In contrast with other elastographic techniques, ascites is considered an exclusion criterion for assessment of fibrosis stage by transient elastography. However, a normal liver stiffness could rule out hepatic causes of ascites at an early stage. The aim of the present study was to determine whether liver stiffness can be generally determined by transient elastography through an ascites layer, to determine whether the ascites-mediated increase in intra-abdominal pressure affects liver stiffness, and to provide initial data from a pilot cohort of patients with various causes of ascites.Methods and results: Using the XL probe in an artificial ascites model, we demonstrated (copolymer phantoms surrounded by water that a transient elastography-generated shear wave allows accurate determination of phantom stiffness up to a water lamella of 20 mm. We next showed in an animal ascites model that increased intra-abdominal pressure does not affect liver stiffness. Liver stiffness was then determined in 24 consecutive patients with ascites due to hepatic (n = 18 or nonhepatic (n = 6 causes. The cause of ascites was eventually clarified using routine clinical, imaging, laboratory, and other tools. Valid (75% or acceptable (25% liver stiffness data could be obtained in 23 patients (95.8% with ascites up to an ascites lamella of 39 mm. The six patients (25% with nonhepatic causes of ascites (eg, pancreatitis, peritoneal carcinomatosis had a

IBM-PC based high voltage controller [Paper No.: L7

International Nuclear Information System (INIS)

Mondal, N.K.; Kalmani, S.D.

1993-01-01

A simple IBM-PC/XT based high voltage controller is designed for C.A.E.N. high voltage supply unit, which is being used for testing the prototype detector for future accelerator experiment. The high voltage output of the supply unit can be remotely programmed. The V-set Lemo connectors at the rear panel provides the remote control facility. Similarly V-mon and I-mon can be used for remotely monitoring the voltage set and the current drawn from the supply unit. The controller described here sets the high voltage through V-set and monitors the voltage set, through V-mon at a pre-determined time interval. The monitoring is a background job and is done as an interrupt service routine of IRQ3. A simple menu driven software package used is written in Q-Basic and MASM. (author). 1 fig

Experiences From NASA/Langley's DMSS Project

Science.gov (United States)

1996-01-01

There is a trend in institutions with high performance computing and data management requirements to explore mass storage systems with peripherals directly attached to a high speed network. The Distributed Mass Storage System (DMSS) Project at the NASA Langley Research Center (LaRC) has placed such a system into production use. This paper will present the experiences, both good and bad, we have had with this system since putting it into production usage. The system is comprised of: 1) National Storage Laboratory (NSL)/UniTree 2.1, 2) IBM 9570 HIPPI attached disk arrays (both RAID 3 and RAID 5), 3) IBM RS6000 server, 4) HIPPI/IPI3 third party transfers between the disk array systems and the supercomputer clients, a CRAY Y-MP and a CRAY 2, 5) a "warm spare" file server, 6) transition software to convert from CRAY's Data Migration Facility (DMF) based system to DMSS, 7) an NSC PS32 HIPPI switch, and 8) a STK 4490 robotic library accessed from the IBM RS6000 block mux interface. This paper will cover: the performance of the DMSS in the following areas: file transfer rates, migration and recall, and file manipulation (listing, deleting, etc.); the appropriateness of a workstation class of file server for NSL/UniTree with LaRC's present storage requirements in mind the role of the third party transfers between the supercomputers and the DMSS disk array systems in DMSS; a detailed comparison (both in performance and functionality) between the DMF and DMSS systems LaRC's enhancements to the NSL/UniTree system administration environment the mechanism for DMSS to provide file server redundancy the statistics on the availability of DMSS the design and experiences with the locally developed transparent transition software which allowed us to make over 1.5 million DMF files available to NSL/UniTree with minimal system outage

Social movement heterogeneity in public policy framing: A multi-stakeholder analysis of the Keystone XL pipeline

Science.gov (United States)

Wesley, David T. A.

In 2011, stakeholders with differing objectives formed an alliance to oppose the Keystone XL heavy oil pipeline. The alliance, which came to be known as "Tar Sands Action," implemented various strategies, some of which were more successful than others. Tar Sands Action was a largely heterogeneous alliance that included indigenous tribes, environmentalists, ranchers, landowners, and trade unions, making it one of the more diverse social movement organizations in history. Each of these stakeholder categories had distinct demographic structures, representing an array of racial, ethnic, educational, occupational, and political backgrounds. Participants also had differing policy objectives that included combating climate change and protecting jobs, agricultural interests, water resources, wildlife, and human health. The current dissertation examines the Tar Sands Action movement to understand how heterogeneous social movement organizations mobilize supporters, maintain alliances, and create effective frames to achieve policy objectives. A multi-stakeholder analysis of the development, evolution and communication of frames concerning the Keystone XL controversy provides insight into the role of alliances, direct action, and the news media in challenging hegemonic frames. Previous research has ignored the potential value that SMO heterogeneity provides by treating social movements as culturally homogenous. However, diversity has been shown to affect performance in business organizations. The current study demonstrates that under some circumstances, diversity can also improve policy outcomes. Moreover, policy frames are shown to be more effective in sustaining news media and public interest through a process the author calls dynamic frame sequencing (DFS). DFS refers to a process implementing different stakeholder frames at strategically opportune moments. Finally, Tar Sands Action was one of the first SMOs to rely heavily on social media to build alliances, disseminate

A full automatic system controlled with IBM-PC/XT micro-computer for neutron activation analysis

International Nuclear Information System (INIS)

Song Quanxun

1992-01-01

A full automatic system controlled with micro-computers for NAA is described. All processes are automatically completed with an IBM-PC/XT micro-computer. The device is stable, reliable, flexible and convenient for use and has many functions and applications in automatical analysis of long, middle and short lived nuclides. Due to a high working efficiency of the instrument and micro-computers, both time and power can be saved. This method can be applied in other nuclear analysis techniques

LFQProfiler and RNP(xl): Open-Source Tools for Label-Free Quantification and Protein-RNA Cross-Linking Integrated into Proteome Discoverer.

Science.gov (United States)

Veit, Johannes; Sachsenberg, Timo; Chernev, Aleksandar; Aicheler, Fabian; Urlaub, Henning; Kohlbacher, Oliver

2016-09-02

Modern mass spectrometry setups used in today's proteomics studies generate vast amounts of raw data, calling for highly efficient data processing and analysis tools. Software for analyzing these data is either monolithic (easy to use, but sometimes too rigid) or workflow-driven (easy to customize, but sometimes complex). Thermo Proteome Discoverer (PD) is a powerful software for workflow-driven data analysis in proteomics which, in our eyes, achieves a good trade-off between flexibility and usability. Here, we present two open-source plugins for PD providing additional functionality: LFQProfiler for label-free quantification of peptides and proteins, and RNP(xl) for UV-induced peptide-RNA cross-linking data analysis. LFQProfiler interacts with existing PD nodes for peptide identification and validation and takes care of the entire quantitative part of the workflow. We show that it performs at least on par with other state-of-the-art software solutions for label-free quantification in a recently published benchmark ( Ramus, C.; J. Proteomics 2016 , 132 , 51 - 62 ). The second workflow, RNP(xl), represents the first software solution to date for identification of peptide-RNA cross-links including automatic localization of the cross-links at amino acid resolution and localization scoring. It comes with a customized integrated cross-link fragment spectrum viewer for convenient manual inspection and validation of the results.

Corrosion of API XL 52 steel in presence of Clostridium celerecrescens

Energy Technology Data Exchange (ETDEWEB)

Monroy, O.A. Ramos; Ordaz, N. Ruiz; Ramirez, C. Juarez [Escuela Nacional de Ciencias Biologicas, Instituto Politecnico Nacional, Prolongacion de Carpio y Plan de Ayala, Mexico D. F., C. P. 11340 (Mexico); Gayosso, M.J. Hernandez; Olivares, G. Zavala [Instituto Mexicano del Petroleo, Grupo Corrosion, Eje Central Lazaro Cardenas 152, Col. San Bartolo Atepehuacan, Mexico D. F., C. P. 07730 (Mexico)

2011-09-15

During the characterization of sediments formed in pipelines transporting hydrocarbons, the knowledge of the microbiological diversity becomes very interesting, especially when it is related to microbiologically influenced corrosion (MIC). The presence of microorganisms is considered as one of the factors that affect the corrosion processes occurring at the pipeline; therefore, their corrosiveness must be determined. In this way, the identification of new species affecting the MIC processes is still considered relevant. In this work, the effect of Clostridium celerecrescens upon the corrosion of API KL 52 steel was evaluated. This microorganism was isolated and identified from the sediments collected during the inner cleaning procedures of a gas pipeline. The polarization resistance (PR) and electrochemical impedance spectroscopy (EIS) techniques were considered to estimate the microorganism behavior during the corrosion process. The results were complemented with a metal surface analysis, using a scanning electron microscope (SEM). The resistance values induced by the presence of the microorganisms clearly indicated that C. celerecrescens has an effect on the corrosion process occurring at the API XL 52 steel surface. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

The finite element structural analysis code SAP IV conversion from CDC to IBM

International Nuclear Information System (INIS)

Harrop, L.P.

1977-02-01

SAP IV is a general three dimensional, linear, static and dynamic finite element structural analysis program. The program which was obtained from the Earthquake Engineering Research Center, University of California, Berkeley, was written in FORTRAM for a CDC 6400. Its main use was anticipated to be the seismic analysis of reactor structures. SAP IV may also prove useful for fracture mechanics studies as well as the usual elastic stress analysis of structures. A brief description of SAP IV and a more detailed account of the FORTRAN conversion required to make SAP IV run successfully on the UKAEA Harwell IBM 370/168 are given. (author)

A recent Cleanroom success story: The Redwing project

Science.gov (United States)

Hausler, Philip A.

1992-12-01

Redwing is the largest completed Cleanroom software engineering project in IBM, both in terms of lines of code and project staffing. The product provides a decision-support facility that utilizes artificial intelligence (AI) technology for predicting and preventing complex operating problems in an MVS environment. The project used the Cleanroom process for development and realized a defect rate of 2.6 errors/KLOC, measured from first execution. This represents the total amount of errors that were found in testing and installation at three field test sites. Development productivity was 486 LOC/PM, which included all development labor expended in design specification through completion of incremental testing. In short, the Redwing team produced a complex systems software product with an extraordinarily low error rate, while maintaining high productivity. All of this was accomplished by a project team using Cleanroom for the first time. An 'introductory implementation' of Cleanroom was defined and used on Redwing. This paper describes the quality and productivity results, the Redwing project, and how Cleanroom was implemented.

Impacts of the IBM Cell Processor to Support Climate Models

Science.gov (United States)

Zhou, Shujia; Duffy, Daniel; Clune, Tom; Suarez, Max; Williams, Samuel; Halem, Milt

2008-01-01

NASA is interested in the performance and cost benefits for adapting its applications to the IBM Cell processor. However, its 256KB local memory per SPE and the new communication mechanism, make it very challenging to port an application. We selected the solar radiation component of the NASA GEOS-5 climate model, which: (1) is representative of column physics (approximately 50% computational time), (2) has a high computational load relative to transferring data from and to main memory, (3) performs independent calculations across multiple columns. We converted the baseline code (single-precision, Fortran) to C and ported it with manually SIMDizing 4 independent columns and found that a Cell with 8 SPEs can process 2274 columns per second. Compared with the baseline results, the Cell is approximately 5.2X, approximately 8.2X, approximately 15.1X faster than a core on Intel Woodcrest, Dempsey, and Itanium2, respectively. We believe this dramatic performance improvement makes a hybrid cluster with Cell and traditional nodes competitive.

Enhancing organization and maintenance of big data with Apache Solr in IBM WebSphere Commerce deployments

OpenAIRE

Grigel, Rudolf

2015-01-01

The main objective of this thesis was to enhance the organization and maintenance of big data with Apache Solr in IBM WebSphere Commerce deployments. This objective can be split into several subtasks: reorganization of data, fast and optimised exporting and importing, efficient update and cleanup operations. E-Commerce is a fast growing and frequently changing environment. There is a constant flow of data that is rapidly growing larger and larger every day which is becoming an ...

A CAMAC crate controller KK009 for the Pravetz-16 and IBM PC/XT personal computers

International Nuclear Information System (INIS)

Georgiev, A.; Churin, I.N.

1988-01-01

A CAMAC crate controller and a computer bus adapter for the Pravetz 16 and IBM PC/XT personal computers are described. The following features are included in the controller: operation under program control; access to CAMAC registers treated as memory locations corresponding to given N, A, F; hardware for fast LAM processing and execution of multi-crate commands; device up to 7 crates in one CAMAC system; built-in hardware for controller and crate dataway test

A microscopic derivation of the dependence of the IBM3 hamiltonian on the boson number and isospin

International Nuclear Information System (INIS)

Evans, J.A.; Long, G.L.P.; Elliott, J.P.

1993-01-01

The number and isospin dependence of the hamiltonian in the isospin invariant form (IBM3) of the boson model has been deduced from a seniority mapping into a single j-shell, making use of shell-model formulae recently obtained from vector coherent state theory. Numerical results are given for a specific shell-model example and the qualitative behaviour of the different parameters in the hamiltonian is discussed. (orig.)

A Conceptual Framework for the Electronic Performance Support Systems within IBM Lotus Notes 6 (LN6 Example

Directory of Open Access Journals (Sweden)

Servet BAYRAM

2005-10-01

Full Text Available A Conceptual Framework for the Electronic PerformanceSupport Systems within IBM Lotus Notes 6 (LN6 Example Assoc. Prof. Dr. Servet BAYRAM Computer Education & Instructional Technologies Marmara University, TURKEYsbayram@marmara.edu.tr ABSTRACT The concept of Electronic Performance Support Systems (EPSS is containing multimedia or computer based instruction components that improves human performance by providing process simplification, performance information and decision support system. EPSS has become a hot topic for organizational development, human resources, performance technology, training, and educational development professionals. A conceptual framework of EPSS is constructed under five interrelated and interdependent domains for educational implications. The domains of the framework are online collaboration, cost-effectiveness, motivation, service management, and performance empowering. IBM Lotus Notes 6 (LN6 is used as an example application tool to illustrate the power of this framework. The framework describes a set of relevant events based upon deductive analyses for improving our understanding of the EPSS and its implications on education and training. The article is also pointed out that there are some similarities between the EPSS’ and the LN6’s specific features within this conceptual framework. It can provide some guidelines and benefits to researchers, educators, and designers as well.

Effect of system workload on operating system reliability - A study on IBM 3081

Science.gov (United States)

Iyer, R. K.; Rossetti, D. J.

1985-01-01

This paper presents an analysis of operating system failures on an IBM 3081 running VM/SP. Three broad categories of software failures are found: error handling, program control or logic, and hardware related; it is found that more than 25 percent of software failures occur in the hardware/software interface. Measurements show that results on software reliability cannot be considered representative unless the system workload is taken into account. The overall CPU execution rate, although measured to be close to 100 percent most of the time, is not found to correlate strongly with the occurrence of failures. Possible reasons for the observed workload failure dependency, based on detailed investigations of the failure data, are discussed.

Adaptation of the IBM ECR [electric cantilever robot] robot to plutonium processing applications

International Nuclear Information System (INIS)

Armantrout, G.A.; Pedrotti, L.R.; Halter, E.A.; Crossfield, M.

1990-12-01

The changing regulatory climate in the US is adding increasing incentive to reduce operator dose and TRU waste for DOE plutonium processing operations. To help achieve that goal the authors have begun adapting a small commercial overhead gantry robot, the IBM electric cantilever robot (ECR), to plutonium processing applications. Steps are being taken to harden this robot to withstand the dry, often abrasive, environment within a plutonium glove box and to protect the electronic components against alpha radiation. A mock-up processing system for the reduction of the oxide to a metal was prepared and successfully demonstrated. Design of a working prototype is now underway using the results of this mock-up study. 7 figs., 4 tabs

Implementation of GENSEC section from HYDRA 3.40 system on IBM 370/135 (DOS/VS 34.0)

International Nuclear Information System (INIS)

Ponta, T.

1984-07-01

In High Energy Physics, processing and interpretation of experimental data, supplied by track-particle detectors, are made by means of HYDRA system. We present here the implementation on IBM 370/135 (DOS/VS 34.0) (belonqing to Central Institute of Physics) of General Section (GENSEC) from HYDRA system, paying a special attention to the description of the 176 routines of this section, in order to facilitate their use on the computer. (author)

Analýza výkonnosti procesorů IBM POWER8

OpenAIRE

Jelen, Jakub

2016-01-01

Práce se zabývá systémem IBM Power8 v porovnání s dnes běžně používanými řešeními s procesory Intel Xeon. Výkonnost je vyhodnocována nejen na úrovni celého systému, ale také na úrovni jednotlivých vláken a jader a paměti. Různé metriky jsou demonstrovány na typických optimalizovaných algoritmech. Testovaný stroj Power8 disponuje extrémně rychlou pamětí poskytující rychlost až 145 GB/s mezi pamětí a procesorem, které se dnešní procesory Intel nevyrovnají. Výpočetní síla je pouze srovnatelná (N...

The SHARPn project on secondary use of Electronic Medical Record data: progress, plans, and possibilities.

Science.gov (United States)

Chute, Christopher G; Pathak, Jyotishman; Savova, Guergana K; Bailey, Kent R; Schor, Marshall I; Hart, Lacey A; Beebe, Calvin E; Huff, Stanley M

2011-01-01

SHARPn is a collaboration among 16 academic and industry partners committed to the production and distribution of high-quality software artifacts that support the secondary use of EMR data. Areas of emphasis are data normalization, natural language processing, high-throughput phenotyping, and data quality metrics. Our work avails the industrial scalability afforded by the Unstructured Information Management Architecture (UIMA) from IBM Watson Research labs, the same framework which underpins the Watson Jeopardy demonstration. This descriptive paper outlines our present work and achievements, and presages our trajectory for the remainder of the funding period. The project is one of the four Strategic Health IT Advanced Research Projects (SHARP) projects funded by the Office of the National Coordinator in 2010.

Guide to data preparation for EQ3/6 (Wolery) modified for the IBM 3033

International Nuclear Information System (INIS)

Noy, D.J.

1981-11-01

The ability to predict mineral-fluid equilibria is an important aspect of geochemical research into radioactive waste disposal. The interaction of ground waters and waste leachates with the host rock of a disposal site, either at elevated or ambient temperatures, will influence the performance of the disposal system. The EQ3/6 package (Wolery, 1979) provides a technique for the prediction of such interactions using available thermodynamic data, and for extrapolating laboratory experimental data on rock-fluid equilibria. This report describes the modifications performed on this package to allow operation on an IBM machine, and is intended as a guide to data preparation for the programmes. (author)

Cloning and expression analysis of genes encoding lytic endopeptidases L1 and L5 from Lysobacter sp. strain XL1.

Science.gov (United States)

Lapteva, Y S; Zolova, O E; Shlyapnikov, M G; Tsfasman, I M; Muranova, T A; Stepnaya, O A; Kulaev, I S; Granovsky, I E

2012-10-01

Lytic enzymes are the group of hydrolases that break down structural polymers of the cell walls of various microorganisms. In this work, we determined the nucleotide sequences of the Lysobacter sp. strain XL1 alpA and alpB genes, which code for, respectively, secreted lytic endopeptidases L1 (AlpA) and L5 (AlpB). In silico analysis of their amino acid sequences showed these endopeptidases to be homologous proteins synthesized as precursors similar in structural organization: the mature enzyme sequence is preceded by an N-terminal signal peptide and a pro region. On the basis of phylogenetic analysis, endopeptidases AlpA and AlpB were assigned to the S1E family [clan PA(S)] of serine peptidases. Expression of the alpA and alpB open reading frames (ORFs) in Escherichia coli confirmed that they code for functionally active lytic enzymes. Each ORF was predicted to have the Shine-Dalgarno sequence located at a canonical distance from the start codon and a potential Rho-independent transcription terminator immediately after the stop codon. The alpA and alpB mRNAs were experimentally found to be monocistronic; transcription start points were determined for both mRNAs. The synthesis of the alpA and alpB mRNAs was shown to occur predominantly in the late logarithmic growth phase. The amount of alpA mRNA in cells of Lysobacter sp. strain XL1 was much higher, which correlates with greater production of endopeptidase L1 than of L5.

The Activity-Based Computing Project - A Software Architecture for Pervasive Computing Final Report

DEFF Research Database (Denmark)

Bardram, Jakob Eyvind

. Special attention should be drawn to publication [25], which gives an overview of the ABC project to the IEEE Pervasive Computing community; the ACM CHI 2006 [19] paper that documents the implementation of the ABC technology; and the ACM ToCHI paper [12], which is the main publication of the project......, documenting all of the project’s four objectives. All of these publication venues are top-tier journals and conferences within computer science. From a business perspective, the project had the objective of incorporating relevant parts of the ABC technology into the products of Medical Insight, which has been...... done. Moreover, partly based on the research done in the ABC project, the company Cetrea A/S has been founded, which incorporate ABC concepts and technologies in its products. The concepts of activity-based computing have also been researched in cooperation with IBM Research, and the ABC project has...

Performance of 2000CA/LL and 2260XL liquid scintillation spectrometers for low-level tritium and carbon-14 analyses

International Nuclear Information System (INIS)

Rozanski, K.; Stichler, W.; Schwarz, P.

1991-01-01

The performance of two commercially available liquid scintillation spectrometers for low-level counting of 3 H and 14 C has been investigated. Two models of new technology Tri-Carb spectrometers from the Packard Instrument Company were tested: the 2000CA/LL and 2260XL. The measurements revealed a superior 3 H performance of the 2000CA/LL equipment owing to its substantially higher counting efficiency. Results for 14 C are less conclusive and depend on the configuration of the counting parameters selected. A comparison of three commercially available scintillation cocktails for tritium assay in water samples revealed a superior performance for PicoFluor LLT. (Author)

IN10 data processing on the Rutherford Laboratory IBM 360

International Nuclear Information System (INIS)

Howells, W.S.; Anderson, I.S.

1978-09-01

This report described modifications made to some of the IN10 spectrometer data analysis programs in use at the Institut Laue-Langevin, Grenoble in order that they may be used on the IBM 360 system at the Rutherford Laboratory. Fuller descriptions of the programs are contained in the original manual (Users' Guide to Processing IN10 Data by W S Howells, ILL Internal Report (1977). Programs discussed are: a) FAST. A program for fitting Lorentzians to raw data. This is a modification of the ILL programs FAST and HAST. b) SUPER. A convolution program for fitting quasielastic peaks to corrected data. This program is based on the ILL program SUPER. c) SAND. A convolution program for fitting an elastic and a Quasielastic peak to data. This is similar to the ILL version of SAND. d) SWIFT. A program similar to SUPER but faster. It is based on the ILL program CONTTY. Before using these programs users must consult the NBRU in order to obtain an account number and a user identifier. (U.K.)

Implementing Open Innovation: The Case of Natura, IBM and Siemens

Directory of Open Access Journals (Sweden)

Cely Ades

2013-05-01

Full Text Available This paper analyses three case firms whose innovation management processes have been consolidated. The companies Natura, IBM (Brazilian Subsidiary and Siemens (ChemTech/Brazil were studied with the purpose of analysing the implementation of OI, particularly in terms of: (a its alignment with existing corporate strategy; (b its requirements such as culture, skill and motivation; (c the strategy and the implementation process; (d the results achieved (e the present barriers and enablers. The research is qualitative in nature and employs a descriptive approach. The main results of this study, obtained using a method called ‘Collective Subject Speech’ , show that the implementation of OI, both structured and non-structured, is mainly challenged by cultural issues. It has been observed that the implementation of OI process is at its embryonic stage in all case firms and that this occurs along with investments in closed innovation, meaning that OI results cannot be explored at this stage of the implementation, as there is a long way to consolidate these practices in the case firms studied.

Implementation of a parallel algorithm for spherical SN calculations on the IBM 3090

International Nuclear Information System (INIS)

Haghighat, A.; Lawrence, R.D.

1989-01-01

Parallel S N algorithms based on domain decomposition in angle are straightforward to develop in Cartesian geometry because the computation of the angular fluxes for a specific discrete ordinate can be performed independently of all other angles. This is not the case for curvilinear geometries, where the angular redistribution component of the discretized streaming operator results in coupling between angular fluxes along adjacent discrete ordinates. Previously, the authors developed a parallel algorithm for S N calculations in spherical geometry and examined its iterative convergence for criticality and detector problems with differing scattering/absorption ratios. In this paper, the authors describe the implementation of the algorithm on an IBM 3090 Model 400 (four processors) and present computational results illustrating the efficiency of the algorithm relative to serial execution

IBM mainframe security beyond the basics : a practical guide from a z/OS and RACF perspective

CERN Document Server

Dattani, Dinesh D

2013-01-01

Rather than rehashing basic information-such as command syntax-already available in other publications, this book focuses on important security and audit issues, business best practices, and compliance, discussing the important issues in IBM mainframe security. Mainframes are the backbone of most large IT organizations; security cannot be left to chance. With very little training available to the younger crowd, and older, more experienced personnel retiring or close to retiring, there is a need in mainframe security skills at the senior level. Based on real-life experiences, issues, and soluti

OSCAR API for Real-Time Low-Power Multicores and Its Performance on Multicores and SMP Servers

Science.gov (United States)

Kimura, Keiji; Mase, Masayoshi; Mikami, Hiroki; Miyamoto, Takamichi; Shirako, Jun; Kasahara, Hironori

OSCAR (Optimally Scheduled Advanced Multiprocessor) API has been designed for real-time embedded low-power multicores to generate parallel programs for various multicores from different vendors by using the OSCAR parallelizing compiler. The OSCAR API has been developed by Waseda University in collaboration with Fujitsu Laboratory, Hitachi, NEC, Panasonic, Renesas Technology, and Toshiba in an METI/NEDO project entitled "Multicore Technology for Realtime Consumer Electronics." By using the OSCAR API as an interface between the OSCAR compiler and backend compilers, the OSCAR compiler enables hierarchical multigrain parallel processing with memory optimization under capacity restriction for cache memory, local memory, distributed shared memory, and on-chip/off-chip shared memory; data transfer using a DMA controller; and power reduction control using DVFS (Dynamic Voltage and Frequency Scaling), clock gating, and power gating for various embedded multicores. In addition, a parallelized program automatically generated by the OSCAR compiler with OSCAR API can be compiled by the ordinary OpenMP compilers since the OSCAR API is designed on a subset of the OpenMP. This paper describes the OSCAR API and its compatibility with the OSCAR compiler by showing code examples. Performance evaluations of the OSCAR compiler and the OSCAR API are carried out using an IBM Power5+ workstation, an IBM Power6 high-end SMP server, and a newly developed consumer electronics multicore chip RP2 by Renesas, Hitachi and Waseda. From the results of scalability evaluation, it is found that on an average, the OSCAR compiler with the OSCAR API can exploit 5.8 times speedup over the sequential execution on the Power5+ workstation with eight cores and 2.9 times speedup on RP2 with four cores, respectively. In addition, the OSCAR compiler can accelerate an IBM XL Fortran compiler up to 3.3 times on the Power6 SMP server. Due to low-power optimization on RP2, the OSCAR compiler with the OSCAR API

Large boson number IBM calculations and their relationship to the Bohr model

International Nuclear Information System (INIS)

Thiamova, G.; Rowe, D.J.

2009-01-01

Recently, the SO(5) Clebsch-Gordan (CG) coefficients up to the seniority v max =40 were computed in floating point arithmetic (T.A. Welsh, unpublished (2008)); and, in exact arithmetic, as square roots of rational numbers (M.A. Caprio et al., to be published in Comput. Phys. Commun.). It is shown in this paper that extending the QQQ model calculations set up in the work by D.J. Rowe and G. Thiamova (Nucl. Phys. A 760, 59 (2005)) to N=v max =40 is sufficient to obtain the IBM results converged to its Bohr contraction limit. This will be done by comparing some important matrix elements in both models, by looking at the seniority decomposition of low-lying states and at the behavior of the energy and B(E2) transition strengths ratios with increasing seniority. (orig.)

Energy levels, radiative rates, and lifetimes for transitions in W XL

International Nuclear Information System (INIS)

Aggarwal, Kanti M.; Keenan, Francis P.

2014-01-01

Energy levels and radiative rates are reported for transitions in Br-like tungsten, W XL, calculated with the general-purpose relativistic atomic structure package (GRASP). Configuration interaction (CI) has been included among 46 configurations (generating 4215 levels) over a wide energy range up to 213 Ryd. However, for conciseness results are only listed for the lowest 360 levels (with energies up to ∼43 Ryd), which mainly belong to the 4s 2 4p 5 ,4s 2 4p 4 4d,4s 2 4p 4 4f,4s4p 6 ,4p 6 4d,4s4p 5 4d,4s 2 4p 3 4d 2 , and 4s 2 4p 3 4d4f configurations, and provided for four types of transitions, E1, E2, M1, and M2. Comparisons are made with existing (but limited) results. However, to fully assess the accuracy of our data, analogous calculations have been performed with the flexible atomic code, including an even larger CI than in GRASP. Our energy levels are estimated to be accurate to better than 0.02 Ryd, whereas results for radiative rates (and lifetimes) should be accurate to better than 20% for a majority of the strong transitions

A BASIC program for an IBM PC compatible computer for drawing the weak phase object contrast transfer function

International Nuclear Information System (INIS)

Olsen, A.; Skjerpe, P.

1989-01-01

This report describes a computer program which is useful in high resolution microscopy. The program is written in EBASIC and calculates the weak phase object contrast transfer function as function of instrumental and imaging parameters. The function is plotted on the PC graphics screen, and by a Print Screen command the function can be copied to the printer. The program runs on both the Hercules graphic card and the IBM CGA card. 2 figs

PRAAGE-1988: An interactive IBM-PC code for aging analysis of NUREG-1150 systems

International Nuclear Information System (INIS)

Fullwood, R.R.; Shier, W.G.

1988-01-01

Probabilistic Risk Assessments (PRA) contain a great deal of information for estimating the risk of a nuclear power plant but do not consider aging. PRAAGE (PRA+AGE) is an interactive, IBM-PC code for processing PRA-developed system models using non-aged failure rate data in conjunction with user-supplied time-dependent nuclear plant experience component failure rate data to determine the effects of component aging on a system's reliability as well as providing the age-dependent importances of various generic components. This paper describes the structure, use and application of PRAAGE to the aging analysis of the Peach Bottom 2 RHR system in the LPCI and SDC modes of operation. 4 refs., 15 figs., 5 tabs

Review of the Environmental Protection Agency’s Common Sense Initiative (The National Shipbuilding Research Program)

Science.gov (United States)

1996-03-01

desired end product of this Work would be a “customer-oriented” research and development strategy for the industy Description of Project: The workgroup is...EPA as they implement EPA programs that have been delegated to them. EPA is taking a decentralized or “ franchising ” approach to the implementation of XL...PROJECT XL FEDERAL REGISTER NOTICE PUBLISHED MAY 22,1995 proposal; reviewing the proposal through respondent management; and consulting in some fashion

GOSPEG-1 a program for routine analysis of γ-ray spectra by an in line IBM S/7 computer

International Nuclear Information System (INIS)

Godio, G.P.; Gozzellino, F.

1977-01-01

In this paper a program for routine analysis of γ-ray spectra of samples coming from irradiated nuclear fuel reprocessing plant is described. An IBM S/7 computer (SK words of memory) which is installed at the CNEN-EUREX reprocessing plant and which is in-line connected with a multichannel analyzer and Ge(Li) detector, has been utilized for this work. The program has been written in Assembler S/7 language

Case study: IBM Watson Analytics cloud platform as Analytics-as-a-Service system for heart failure early detection

OpenAIRE

Guidi, Gabriele; Miniati, Roberto; Mazzola, Matteo; Iadanza, Ernesto

2016-01-01

In the recent years the progress in technology and the increasing availability of fast connections have produced a migration of functionalities in Information Technologies services, from static servers to distributed technologies. This article describes the main tools available on the market to perform Analytics as a Service (AaaS) using a cloud platform. It is also described a use case of IBM Watson Analytics, a cloud system for data analytics, applied to the following research scope: detect...

IBM PARENTING BAGI GURU DAN ORANG TUA PAUD DI KELURAHAN PUDAK PAYUNG SEMARANG

Directory of Open Access Journals (Sweden)

Retnaningdyastuti .

2015-09-01

Full Text Available Abstract Science and technology program for the community (IbM aims to provide teachers and parents knowledges and skills in educating early childhood, especially in the form of parenting and child counseling. The methods used in the implementation of community service activities on developing character of early childhood through modeling and and habituation in the form of counseling and mentoring, such as playing games involving both parents and children. The result shows that the implementation of early childhood education has good responses from the participants. Through habituation and modeling given by teachers/ educators and parents, the activities can convey moral messages to children. Hopefully the children can be developed to have intelligent and healthy personality, and virtuous character. Keywords: early childhood education, parenting, and child counseling

Structural variations and dielectric properties of (Bi1-xL ax ) 2Si O5 (0 ≤x ≤0.1 ): Polycrystallines synthesized by crystallization of Bi-Si-O and Bi-La-Si-O glasses

Science.gov (United States)

Taniguchi, Hiroki; Tatewaki, Shingo; Yasui, Shintaro; Fujii, Yasuhiro; Yamaura, Jun-ichi; Terasaki, Ichiro

2018-04-01

This paper focuses on effects of isovalent La substitution on the crystal structure and dielectric properties of ferroelectric B i2Si O5 . Polycrystalline samples of (Bi1-xL ax ) 2Si O5 are synthesized by crystallization of Bi-Si-O and Bi-La-Si-O glasses with a composition range of 0 ≤x ≤0.1 . The crystal structure changes from monoclinic to tetragonal with increasing La-substitution rate x at room temperature. This structural variation stems from the change in orientation of Si O4 tetrahedra that form one-dimensional chains when they are in the ordered configuration, thus suggesting that lone-pair electrons play an important role in sustaining one-dimensional chains of Si O4 tetrahedra. Synchronizing with the disordering of Si O4 chains, ferroelectric phase transition temperature of (Bi1-xL ax ) 2Si O5 sharply decreases as x increases, and ferroelectricity finally vanishes at around x =0.03 . The present results demonstrate that lone-pair electrons of Bi play an important role in the ferroelectricity of B i2Si O5 through propping the ordered structure of one-dimensional Si O4 chains with stereochemical activity. Furthermore, an additional phase transition has been first discovered in the low-temperature region of (Bi1-xL ax ) 2Si O5 with x ≤0.01 , where the ordered one-dimensional Si O4 chains remain.

Cathodic protection of XL 52 steel under the influence of sulfate reducing bacteria

Energy Technology Data Exchange (ETDEWEB)

Esquivel, R. Garcia [Instituto Mexicano del Petroleo, Eje Central Lazaro Cardenas No. 152, Col. San Bartolo Atepehuacan, Mexico, D.F. 07730 (Mexico); Departamento de lngenieria Metalurgica, Facultad de Quimica, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, 04510 Mexico, D.F. (Mexico); Olivares, G. Zavala; Gayosso, M.J. Hernandez; Trejo, A. Gayosso [Instituto Mexicano del Petroleo, Eje Central Lazaro Cardenas No. 152, Col. San Bartolo Atepehuacan, Mexico, D.F. 07730 (Mexico)

2011-01-15

The effect of sulfate reducing bacteria (SRB) upon the cathodic protection of XL 52 steel was determined, in order to identify if the potential value of -0.950 V versus copper/copper sulfate electrode is good enough to protect the metal surface. During the experiments, different operational parameters were monitored: hydrogen sulfide production, iron concentration, electrolyte alkalinity, microorganisms' population, as well as the metal surface damage. At the same time, the corrosion rate was determined using two electrochemical techniques: polarization resistance (PR) and electrochemical impedance spectroscopy (EIS). According to the results, it was observed that the protection potential of -0.950 V versus copper/copper sulfate electrode is not enough to control the microbiologically induced corrosion. This situation is reinforced by the fact that significant iron concentration was found in the electrolyte. The microbiological activity is not affected by the protection potential. On the contrary, the population growth is slightly strengthened. The alkalinity generated by the applied potential did not stop the SRB growth. A type of localized corrosion was developed during the experiments with microorganisms, even when the protection potential was applied to the system. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Halonium Ions as Halogen Bond Donors in the Solid State [XL2]Y Complexes.

Science.gov (United States)

Rissanen, Kari; Haukka, Matti

2015-01-01

The utilization of halogen bonding interactions is one of the most rapidly developing areas of supramolecular chemistry. While the other weak non-covalent interactions and their influence on the structure and chemistry of various molecules, complexes, and materials have been investigated extensively, the understanding, utilizations, and true nature of halogen bonding are still relatively unexplored. Thus its final impact in chemistry in general and in materials science has not yet been fully established. Because of the polarized nature of a Z-X bond (Z=electron-withdrawing atom or moiety and X=halogen atom), such a moiety can act as halogen bond donor when the halogen is polarized enough by the atom/moiety Z. The most studied and utilized halogen bond donor molecules are the perfluorohalocarbons, where Z is a perfluorinated aryl or alkyl moiety and X is either iodine or bromine. Complementing the contemporary halogen bonding research, this chapter reviews the solid state structural chemistry of the most extremely polarized halogen atoms, viz. halonium ions, X+, and discussed them as halogen bond donors in the solid state [XL2]Y complexes (X=halonium ion, Y=any anion).

Portable regional cerebral blood flow system based on IBM PC/AT and microprocessor electronics

International Nuclear Information System (INIS)

Mun, S.K.; Mun, I.K.; Petite, J.; Cohan, S.L.; Fahey, F.H.

1986-01-01

A portable 16-channel reginal cerebral blood flow (rCBF) measuring system has been developed using an IBM PC/AT and new microelectronics to improve processing speed and portability. The detector electronics were developed by Scan Detectronics A/S of Denmark. The counter module contains 18 16-bit counters, each programmable in four different modes. The rate meter has three independent microprocessor controllers for rate meter functions, window controller, and channel controller. The detector electronics and detection parameters can be fully controlled by the host PC/AT. The menu-driven system (Better Basic) assists the operator at each step. The collected data from 16 channels can be processed automatically or postprocessed using more flexible and sophisticated techniques within 20 minutes. The headgear holding 16 sodium iodide detectors is fabricated by modifying a motorcycle helmet

Efficient universal quantum channel simulation in IBM's cloud quantum computer

Science.gov (United States)

Wei, Shi-Jie; Xin, Tao; Long, Gui-Lu

2018-07-01

The study of quantum channels is an important field and promises a wide range of applications, because any physical process can be represented as a quantum channel that transforms an initial state into a final state. Inspired by the method of performing non-unitary operators by the linear combination of unitary operations, we proposed a quantum algorithm for the simulation of the universal single-qubit channel, described by a convex combination of "quasi-extreme" channels corresponding to four Kraus operators, and is scalable to arbitrary higher dimension. We demonstrated the whole algorithm experimentally using the universal IBM cloud-based quantum computer and studied the properties of different qubit quantum channels. We illustrated the quantum capacity of the general qubit quantum channels, which quantifies the amount of quantum information that can be protected. The behavior of quantum capacity in different channels revealed which types of noise processes can support information transmission, and which types are too destructive to protect information. There was a general agreement between the theoretical predictions and the experiments, which strongly supports our method. By realizing the arbitrary qubit channel, this work provides a universally- accepted way to explore various properties of quantum channels and novel prospect for quantum communication.

Speakeasy-3 reference manual. Level MU. IBM OS/VS version

International Nuclear Information System (INIS)

Cohen, S.; Pieper, S.C.

1977-08-01

Speakeasy is a computer language designed to provide access to information stored in a computer. Ease of use, natural notation, and built-in capabilities for growth are important features of Speakeasy. The language is based on the concepts of arrays and matrices, and processes these as entities; the need for many of the loops necessary in other programing languages is thus eliminated. It has a large vocabulary (over 500 words) of functions and commands in the areas of array manipulation, matrix algebra including eigenanalysis, special mathematical functions, numerical integration and differentiation, statistics, graphics, and character processing. It can be used either in batch mode or interactively. This book is the primary reference manual for the Speakeasy language and presents a nearly complete description of its capabilities. The chapters deal with the use of Speakeasy as a ''super desk calculator,'' the construction and editing of Speakeasy programs, the ability to communicate with other programing languages, the construction of user-written additions to the language, and various other facets of Speakeasy. In addition, a complete listing of the Help Library, which contains brief descriptions of each of the Speakeasy functions or commands, is included. This edition applies to the Mu release of Speakeasy-3, and describes the IBM OS/VS version. 18 figures

Communication overhead on the Intel Paragon, IBM SP2 and Meiko CS-2

Science.gov (United States)

Bokhari, Shahid H.

1995-01-01

Interprocessor communication overhead is a crucial measure of the power of parallel computing systems-its impact can severely limit the performance of parallel programs. This report presents measurements of communication overhead on three contemporary commercial multicomputer systems: the Intel Paragon, the IBM SP2 and the Meiko CS-2. In each case the time to communicate between processors is presented as a function of message length. The time for global synchronization and memory access is discussed. The performance of these machines in emulating hypercubes and executing random pairwise exchanges is also investigated. It is shown that the interprocessor communication time depends heavily on the specific communication pattern required. These observations contradict the commonly held belief that communication overhead on contemporary machines is independent of the placement of tasks on processors. The information presented in this report permits the evaluation of the efficiency of parallel algorithm implementations against standard baselines.

Parallel Scaling Characteristics of Selected NERSC User ProjectCodes

Energy Technology Data Exchange (ETDEWEB)

Skinner, David; Verdier, Francesca; Anand, Harsh; Carter,Jonathan; Durst, Mark; Gerber, Richard

2005-03-05

This report documents parallel scaling characteristics of NERSC user project codes between Fiscal Year 2003 and the first half of Fiscal Year 2004 (Oct 2002-March 2004). The codes analyzed cover 60% of all the CPU hours delivered during that time frame on seaborg, a 6080 CPU IBM SP and the largest parallel computer at NERSC. The scale in terms of concurrency and problem size of the workload is analyzed. Drawing on batch queue logs, performance data and feedback from researchers we detail the motivations, benefits, and challenges of implementing highly parallel scientific codes on current NERSC High Performance Computing systems. An evaluation and outlook of the NERSC workload for Allocation Year 2005 is presented.

Studies at IBM on anisotropy in single crystals of the high-temperature oxide superconductor Y1Ba2Cu3O7/sub -//sub x/ (invited)

International Nuclear Information System (INIS)

Gallagher, W.J.

1988-01-01

A series of studies carried out at IBM on the magnetic, transport, and optical properties of single crystal Y 1 Ba 2 Cu 3 O/sub 7-//sub x/ demonstrate the overriding importance of anisotropy in its superconducting and normal-state properties

Analisis Pengaruh Stres Kerja, Beban Kerja dan Lingkungan Kerja terhadap Turnover Intention Karyawan pada PT XL Axiata Tbk Jakarta

Directory of Open Access Journals (Sweden)

Laksmi Sito Dwi Irvianti

2015-05-01

Full Text Available This study aims to determine the effect of job stress, workload and work environment to employee turnover intention PT XL Axiata Tbk Jakarta. This study used survey research and data collection technique used are observation, interviews, literature studies and questionnaires distributed through 81 employees as respondents. The collected data was analyzed by using simple and multiple regression. From the research, it is known variables X1 (job stress partially influence on the variable Y (turnover intention. The X2 variable (workload partially influence variable Y (turnover intention. While the X3 variable (work environment partially influence variable Y (turnover intention And unknown variables X1 (job stress, X2 (workload and X3 (work environment influences variable Y (turnover intention simultaneously.

AMDLIBF, IBM 360 Subroutine Library, Eigenvalues, Eigenvectors, Matrix Inversion

International Nuclear Information System (INIS)

Wang, Jesse Y.

1980-01-01

Description of problem or function: AMDLIBF is a subset of the IBM 360 Subroutine Library at the Applied Mathematics Division at Argonne. This subset includes library category F: Identification/Description: F152S F SYMINV: Invert sym. matrices, solve lin. systems; F154S A DOTP: Double plus precision accum. inner prod.; F156S F RAYCOR: Rayleigh corrections for eigenvalues; F161S F XTRADP: A fast extended precision inner product; F162S A XTRADP: Inner product of two DP real vectors; F202S F1 EIGEN: Eigen-system for real symmetric matrix; F203S F: Driver for F202S; F248S F RITZIT: Largest eigenvalue and vec. real sym. matrix; F261S F EIGINV: Inverse eigenvalue problem; F313S F CQZHES: Reduce cmplx matrices to upper Hess and tri; F314S F CQZVAL: Reduce complex matrix to upper Hess. form; F315S F CQZVEC: Eigenvectors of cmplx upper triang. syst.; F316S F CGG: Driver for complex general Eigen-problem; F402S F MATINV: Matrix inversion and sol. of linear eqns.; F403S F: Driver for F402S; F452S F CHOLLU,CHOLEQ: Sym. decomp. of pos. def. band matrices; F453S F MATINC: Inversion of complex matrices; F454S F CROUT: Solution of simultaneous linear equations; F455S F CROUTC: Sol. of simultaneous complex linear eqns.; F456S F1 DIAG: Integer preserving Gaussian elimination

IBM1, a JmjC domain-containing histone demethylase, is involved in the regulation of RNA-directed DNA methylation through the epigenetic control of RDR2 and DCL3 expression in Arabidopsis

Science.gov (United States)

Fan, Di; Dai, Yan; Wang, Xuncheng; Wang, Zhenjie; He, Hang; Yang, Hongchun; Cao, Ying; Deng, Xing Wang; Ma, Ligeng

2012-01-01

Small RNA-directed DNA methylation (RdDM) is an important epigenetic pathway in Arabidopsis that controls the expression of multiple genes and several developmental processes. RNA-DEPENDENT RNA POLYMERASE 2 (RDR2) and DICER-LIKE 3 (DCL3) are necessary factors in 24-nt small interfering RNA (siRNA) biogenesis, which is part of the RdDM pathway. Here, we found that Increase in BONSAI Methylation 1 (IBM1), a conserved JmjC family histone demethylase, is directly associated with RDR2 and DCL3 chromatin. The mutation of IBM1 induced the hypermethylation of H3K9 and DNA non-CG sites within RDR2 and DCL3, which repressed their expression. A genome-wide analysis suggested that the reduction in RDR2 and DCL3 expression affected siRNA biogenesis in a locus-specific manner and disrupted RdDM-directed gene repression. Together, our results suggest that IBM1 regulates gene expression through two distinct pathways: direct association to protect genes from silencing by preventing the coupling of histone and DNA methylation, and indirect silencing of gene expression through RdDM-directed repression. PMID:22772985

IBM Software Defined Storage and ownCloud Enterprise Editon - a perfect match for hyperscale Enterprise File Sync and Share

CERN Multimedia

CERN. Geneva

2014-01-01

IBM Software Defined Storage, in particular the technology offering codenamed Elastic Storage (based on GPFS technology) has proven to be an ideal match for Enterprise File Sync and Share (EFSS) solutions that need highly scalable storage. The presentation will provide insight into the integration of Elastic Storage with the ownCloud Enterprise Edition (based on Open Source technology) software that showed impressive scalability and performance metrics during a proof-of-concept phase of an installation that is supposed to serve 300000 users when fully deployed.

Preparation of development plan for the gas-condensate pool with the use of a high speed computer (IBM-1620)

Energy Technology Data Exchange (ETDEWEB)

Shirkovsky, A I; Kumar, S

1968-01-01

The computation of all the technical, technological, and economic figures for a gas supply system by using the High Speed Computer IBM-1620 is presented. The gas supply system consists of a gas-condensate pool (source) and main gas pipeline from the pool to the consumer. All necessary analytical equations for correlating geological, technological, and economic variables have been used. Results of calculations and recommendations for the most profitable variant are given. Effects of geological, technological, and technical factors upon the economic figures are also shown.

A program to operate the TSI electrical aerosol analyser using an IBM-PC microcomputer - technical background

International Nuclear Information System (INIS)

Horton, K.D.; Mitchell, J.P.; Snelling, K.W.

1988-02-01

A program has been written to enable the TSI Electrical Aerosol Analyser (EAA model 3030) to be operated using an IBM-PC microcomputer. Although much of the program is based on the software supplied by TSI Inc to collect and process data from the EAA, it incorporates numerous improvements including the option to operate the EAA automatically via a TSI Differential Mobility Particle Sizer interface. When compiled, the program enables the data reduction which takes into account the significant cross-channel sensitivity of the EAA, to be performed in about 30 seconds making it possible to use the EAA to monitor rapid changes in the behaviour of sub-micron aerosol particles. (author)

Index of French nuclear literature: IBM 360 programmes for preparing the permuted index of French titles

International Nuclear Information System (INIS)

Chonez, Nicole

1968-12-01

This report contains the assembly list, the flow chart and some comments about each of the IBM 360 assembler language programmes used for preparing one of the subject indexes contained in the bibliographical bulletin entitled: 'Index de la Litterature nucleaire francaise'; this bulletin has been produced by the French C.E.A. since 1968. Only the processing phases from the magnetic tape file of the bibliographical references, assumed correct, to the printing out of the permuted index obtained with the French titles of the documents on the tape are considered here. This permuted index has the peculiarity of automatically regrouping synonyms and certain grammatical variations of the words. (author) [fr

Modeling radiative transport in ICF plasmas on an IBM SP2 supercomputer

International Nuclear Information System (INIS)

Johansen, J.A.; MacFarlane, J.J.; Moses, G.A.

1995-01-01

At the University of Wisconsin-Madison the authors have integrated a collisional-radiative-equilibrium model into their CONRAD radiation-hydrodynamics code. This integrated package allows them to accurately simulate the transport processes involved in ICF plasmas; including the important effects of self-absorption of line-radiation. However, as they increase the amount of atomic structure utilized in their transport models, the computational demands increase nonlinearly. In an attempt to meet this increased computational demand, they have recently embarked on a mission to parallelize the CONRAD program. The parallel CONRAD development is being performed on an IBM SP2 supercomputer. The parallelism is based on a message passing paradigm, and is being implemented using PVM. At the present time they have determined that approximately 70% of the sequential program can be executed in parallel. Accordingly, they expect that the parallel version will yield a speedup on the order of three times that of the sequential version. This translates into only 10 hours of execution time for the parallel version, whereas the sequential version required 30 hours

AMDLIBGZ, IBM 360 Subroutine Library for Data Processing, Graphics, Sorting

International Nuclear Information System (INIS)

Wang, Jesse Y.

1980-01-01

Description of problem or function: AMDLIBGZ is a subset of the IBM 360 Subroutine Library at the Applied Mathematics Division at Argonne National Laboratory. This subset includes library categories G-Z: Identification/Description: G552S F RANF: Random number generator; J952S F YOLYPLOT: CalComp plots; J955S P GRAF: Prints a graph of points on line printer; K250S A1: Core to core conversion; K251S A HEXINP: Hexadecimal input for PL/I programs; K252S A HEXOUT: Hexadecimal output conv. PL/I programs; M101S F SORT: Algebraic sort; M150S F CSORT: Algebraic sort; M151S P2 ANLKWIC: KWIC sort; M250S A SMALLIST: Squeezes assembler listing to 8 x 11; N251S A ABEND: Calls ABEND dump; Q052S A CLOCK: Time; Q053S A COPYAGO: Copy load module from tape to disk; Q054S A DATE: Current date in form MM/DD/YY; Q055S A TIME: Time (24 hour clock) in EBCDIC HH.MM.SS; Z013S F: Variable metric minimization; Z057S A LOCF: Locate machine addresses of variables; Z071S A ALLOC: Allocate LCS for FORTRAN programs; Z074S A ANLMNP: Exponent and mantissa manipulative functs.

Social construction and physical nihilation of the Keystone XL pipeline: Lessons from international relations theory

International Nuclear Information System (INIS)

Shum, Robert Y.

2013-01-01

If a prime goal of energy policy is to achieve energy security, why is there a controversy over the proposed Keystone XL pipeline, designed to deliver new supplies of oil from within North America? This Viewpoint seeks answers in the debate over the underlying purposes of energy policy: how does one answers the question “what do we want from energy policy?” Perceptions of feasible answers and policy options change over time, as witnessed in the 1970s. Analogous shifts in opinion are changing today's policy debates and widening the contradictions in policy purposes. Attention to the existence of these contradictions, without illusions, is necessary to meet the policy challenges of the future effectively. - Highlights: • We apply international relations theory to explain the persistence of the Keystone controversy. • Key question relates to policy purposes: “what do we want from energy policy?” • Alternative purposes: maximizing economic growth or ensuring environmental sustainability. • 1970s US cases show how perceptions of each purpose's relative feasibility shift. • Different purposes generate different attitudes to policies that result in higher oil prices

From Electrons Paired to Electric Power Delivered- A Personal Journey in Research and Applications of Superconductivity at IBM, EPRI, and Beyond

Science.gov (United States)

Grant, Paul

2014-03-01

This talk will reprise a personal journey by the speaker in industrial and applied physics, commencing with his employment by IBM at age 17 in the early 1950s, and continuing through his corporate sponsored undergraduate and graduate years at Clarkson and Harvard Universities, resulting in 1965 in a doctorate in applied physics from the latter. He was subsequently assigned by IBM to its research division in San Jose (now Almaden), where he initially carried out both pure and applied theoretical and experimental investigations encompassing a broad range of company-related product technologies...storage, display, printer and data acquisition hardware and software. In 1973, he undertook performing DFT and quantum Monte Carlo calculations in support of group research in the then emerging field of organic and polymer superconductors, a very esoteric pursuit at the time. Following upon several corporate staff assignments involving various product development and sales strategies, in 1982 he was appointed manager of the cooperative phenomena group in the Almaden Research Center, which beginning in early 1987, made significant contributions to both the basic science and applications of high temperature superconductivity (HTSC). In 1993, after a 40-year career, he retired from IBM to accept a Science Fellow position at the Electric Power Research Institute (EPRI) where he funded power application development of superconductivity. In 2004, he retired from his EPRI career to undertake ``due diligence'' consulting services in support of the venture capital community in Silicon Valley. As a ``hobby,'' he currently pursues and publishes DFT studies in hope of discovering the pairing mechanism of HTSC. In summary, the speaker's career in industrial and applied physics demonstrates one can combine publishing a record three PRLs in one month with crawling around underground in substations with utility lineman helping install superconducting cables, along the way publishing 10

First experimental results from IBM/TENN/TULANE/LLNL/LBL undulator beamline at the advanced light source

International Nuclear Information System (INIS)

Jia, J.J.; Callcott, T.A.; Yurkas, J.; Ellis, A.W.; Himpsel, F.J.; Samant, M.G.; Stoehr, J.; Ederer, D.L.; Carlisle, J.A.; Hudson, E.A.; Terminello, L.J.; Shuh, D.K.; Perera, R.C.C.

1995-01-01

The IBM/TENN/TULANE/LLNL/LBL Beamline 8.0 at the advanced light source combining a 5.0 cm, 89 period undulator with a high-throughput, high-resolution spherical grating monochromator, provides a powerful excitation source over a spectral range of 70--1200 eV for surface physics and material science research. The beamline progress and the first experimental results obtained with a fluorescence end station on graphite and titanium oxides are presented here. The dispersive features in K emission spectra of graphite excited near threshold, and found a clear relationship between them and graphite band structure are observed. The monochromator is operated at a resolving power of roughly 2000, while the spectrometer has a resolving power of 400 for these fluorescence experiments

A Monte Carlo program for calculating high energy spectra in cylindrical geometry on the IBM 709 computer

Energy Technology Data Exchange (ETDEWEB)

Francescon, S [Computer Branch, Technical Assessments and Services Division, Atomic Energy Establishment, Winfrith, Dorchester, Dorset (United Kingdom)

1960-10-15

The report describes an I.B.M. 709 program written at the request of the Reactor Division, Harwell, to obtain high energy spectra in a system containing a number of fissile and non-fissile materials, arranged as concentric cylinders of infinite length surrounded by an outer material with a square or rectangular boundary. At the cell boundary neutrons can be lost by leakage or reflected back into the system. A specified number of fission neutrons born in the fissile materials, together with any descendants they may have, are tracked one by one through the system until they are absorbed, lost by leakage through the lattice boundary, or their energies have fallen below a specifiable cut-off energy. The neutrons may be started from anywhere in the system and all neutron-nucleus reactions that occur in the nuclides supplied with the program are allowed. A descriptions is given of the use of the program, the current version of which is available as a self-loading binary tape which contains, in addition to the program, all the nuclear data at present available. Binary card decks are also available and nuclear data for other nuclides can be added. A feature of the program is the flexibility with which the core storage available for input and output data can be allocated according to the requirements of the problem. The output of the program is in the form of a Binary Coded Decimal tape (B.C.D.) which can be used on the normal I.B.M. off-line equipment to print out the results. An example is given of the results obtained for use in radiation damage calculations of the spatial distribution of neutrons in a simple uranium-D{sub 2}O system.

CLIPS 6.0 - C LANGUAGE INTEGRATED PRODUCTION SYSTEM, VERSION 6.0 (IBM PC VERSION)

Science.gov (United States)

Donnell, B.

1994-01-01

COOL (that is, a rule can pattern match on objects created using COOL). CLIPS 6.0 provides the capability to define functions, overloaded functions, and global variables interactively. In addition, CLIPS can be embedded within procedural code, called as a subroutine, and integrated with languages such as C, FORTRAN and Ada. CLIPS can be easily extended by a user through the use of several well-defined protocols. CLIPS provides several delivery options for programs including the ability to generate stand alone executables or to load programs from text or binary files. CLIPS 6.0 provides support for the modular development and execution of knowledge bases with the defmodule construct. CLIPS modules allow a set of constructs to be grouped together such that explicit control can be maintained over restricting the access of the constructs by other modules. This type of control is similar to global and local scoping used in languages such as C or Ada. By restricting access to deftemplate and defclass constructs, modules can function as blackboards, permitting only certain facts and instances to be seen by other modules. Modules are also used by rules to provide execution control. The CRSV (Cross-Reference, Style, and Verification) utility included with previous version of CLIPS is no longer supported. The capabilities provided by this tool are now available directly within CLIPS 6.0 to aid in the development, debugging, and verification of large rule bases. COSMIC offers four distribution versions of CLIPS 6.0: UNIX (MSC-22433), VMS (MSC-22434), MACINTOSH (MSC-22429), and IBM PC (MSC-22430). Executable files, source code, utilities, documentation, and examples are included on the program media. All distribution versions include identical source code for the command line version of CLIPS 6.0. This source code should compile on any platform with an ANSI C compiler. Each distribution version of CLIPS 6.0, except that for the Macintosh platform, includes an executable for the

GPIB interface of IBM-PC compatible microcomputer and multimeter HP3457A for the automatization of temperature measurements

International Nuclear Information System (INIS)

Migliano, A.C.C.; Sircilli Neto, F.; Passaro, A.

1990-01-01

The measurement of temperature distribution of the beam transport devices, utilized in the IEAv linac, takes several hours to be completed. At the beam transport laboratory, these experiments are controlled with the help of a MS-quick BASIC code denominated TERMOJ. This code uses the software of STD-8410 plate to promote the communication between an IBM-PC compatible microcomputer and the programmable multimeter HP3457A via GPIB interface. This work presents information for the automation of experiments using thermocouples to obtain temperature distributions with the TERMOJ code. Also, suggestions of how modify the algorithm of the program for the specific situations are indicated. (author)

The Durham elementary particle data bank, data analysis and model comparison project

CERN Document Server

Gault, F D; Chadwick, B; Cooper, C S

1973-01-01

In comparing theoretical models with data the first problem encountered is the retrieval of data from published sources and its storage in such a way as to make it readily accessible. The second is to implement programs which check the data for consistency and any recurring characteristics. The third is to produce an efficiently written program to compare the theoretical model with the data, the program being written as a function of N parameters so that it can be coupled to a minimizing program such as CERN MINUIT. Between each step, interface, retrieval and storage problems arise. The authors discuss the organization of the Durham project, the Data Bank software and retrieval techniques and the integration of model independent software with the Data Bank. This project is being carried out on the Northumbrian Universities Multiple Access Computer (NUMAC) an IBM 360 /67 operating under the Michigan Terminal System (MTS). (10 refs).

Determination of performance characteristics of scientific applications on IBM Blue Gene/Q

Energy Technology Data Exchange (ETDEWEB)

Evangelinos, C. [IBM Research Division, Cambridge, MA (United States); Walkup, R. E. [IBM, Yorktown Heights, NY (United States). Thomas J. Watson Research Center; Sachdeva, V. [IBM Research Division, Cambridge, MA (United States); Jordan, K. E. [IBM Research Division, Cambridge, MA (United States); Gahvari, H. [Univ. of Illinois, Urbana-Champaign, IL (United States). Computer Science Dept.; Chung, I. -H. [IBM, Yorktown Heights, NY (United States). Thomas J. Watson Research Center; Perrone, M. P. [IBM, Yorktown Heights, NY (United States). Thomas J. Watson Research Center; Lu, L. [IBM, Yorktown Heights, NY (United States). Thomas J. Watson Research Center; Liu, L. -K. [IBM, Yorktown Heights, NY (United States). Thomas J. Watson Research Center; Magerlein, K. [IBM, Yorktown Heights, NY (United States). Thomas J. Watson Research Center

2013-02-13

The IBM Blue Gene®/Q platform presents scientists and engineers with a rich set of hardware features such as 16 cores per chip sharing a Level 2 cache, a wide SIMD (single-instruction, multiple-data) unit, a five-dimensional torus network, and hardware support for collective operations. Especially important is the feature related to cores that have four “hardware threads,” which makes it possible to hide latencies and obtain a high fraction of the peak issue rate from each core. All of these hardware resources present unique performance-tuning opportunities on Blue Gene/Q. We provide an overview of several important applications and solvers and study them on Blue Gene/Q using performance counters and Message Passing Interface profiles. We also discuss how Blue Gene/Q tools help us understand the interaction of the application with the hardware and software layers and provide guidance for optimization. Furthermore, on the basis of our analysis, we discuss code improvement strategies targeting Blue Gene/Q. Information about how these algorithms map to the Blue Gene® architecture is expected to have an impact on future system design as we move to the exascale era.

Maintenance Manual for AUDIT. A System for Analyzing SESCOMP Software. Volume 4: Appendix D. Listings of the AUDIT Software for the IBM 360.

Science.gov (United States)

1977-08-01

The AUDIT documentation provides the maintenance programmer personnel with the information to effectively maintain and use the AUDIT software. The ...SESCOMPSPEC’s) and produces reports detailing the deviations from those standards. The AUDIT software also examines a program unit to detect and report...changes in word length on the output of computer programs. This report contains the listings of the AUDIT software for the IBM 360. (Author)

Numerical analysis of resonances induced by s wave neutrons in transmission time-of-flight experiments with a computer IBM 7094 II; Methodes d'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol et automatisation de ces methodes sur ordinateur IBM 7094 II

Energy Technology Data Exchange (ETDEWEB)

Corge, Ch [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1969-01-01

Numerical analysis of transmission resonances induced by s wave neutrons in time-of-flight experiments can be achieved in a fairly automatic way on an IBM 7094/II computer. The involved computations are carried out following a four step scheme: 1 - experimental raw data are processed to obtain the resonant transmissions, 2 - values of experimental quantities for each resonance are derived from the above transmissions, 3 - resonance parameters are determined using a least square method to solve the over determined system obtained by equalling theoretical functions to the correspondent experimental values. Four analysis methods are gathered in the same code, 4 - graphical control of the results is performed. (author) [French] L'automatisation, sur ordinateur IBM 7094/II, de l'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol a ete accomplie en la decomposant selon un schema articule en quatre phases: 1 - le traitement des donnees experimentales brutes pour obtenir les transmissions interfero-resonnantes, 2 - la determination des grandeurs d'analyse a partir des transmissions precedentes, 3 - l'analyse proprement dite des resonances dont les parametres sont obtenus par la resolution d'un systeme surabondant. Quatre methodes d'analyse sont groupees en un meme programme, 4 - la procedure de verification graphique. (auteur)

Solar energy system performance evaluation report for IBM System 4 at Clinton, Mississippi

Science.gov (United States)

1980-07-01

The IBM System 4 Solar Energy System is described and evaluated. The system was designed to provide 35 percent of the space heating and 63 percent of the domestic hot water preheating for a single family residence located within the United States. The system consists of 259 square feet of flat plate air collectors, a rock thermal storage containing 5 1/2 ton of rock, heat exchangers, blowers, a 52 gallon preheat tank, controls, and associated plumbing. In general, the performance of the system did not meet design expectations, since the overall design solar fraction was 48 percent and the measured value was 32 percent. Although the measured space heating solar fraction at 32 percent did agree favorably with the design space heating solar fraction at 35 percent, the hot water measured solar fraction at 33 percent did not agree favorably with the design hot water solar fraction of 63 percent. In particular collector array air leakage, dust covered collectors, abnormal hot water demand, and the preheat tank by pass valve problem are main reasons for the lower performance.

ProjectQ: an open source software framework for quantum computing

Directory of Open Access Journals (Sweden)

Damian S. Steiger

2018-01-01

Full Text Available We introduce ProjectQ, an open source software effort for quantum computing. The first release features a compiler framework capable of targeting various types of hardware, a high-performance simulator with emulation capabilities, and compiler plug-ins for circuit drawing and resource estimation. We introduce our Python-embedded domain-specific language, present the features, and provide example implementations for quantum algorithms. The framework allows testing of quantum algorithms through simulation and enables running them on actual quantum hardware using a back-end connecting to the IBM Quantum Experience cloud service. Through extension mechanisms, users can provide back-ends to further quantum hardware, and scientists working on quantum compilation can provide plug-ins for additional compilation, optimization, gate synthesis, and layout strategies.

Parallelism at Cern: real-time and off-line applications in the GP-MIMD2 project

International Nuclear Information System (INIS)

Calafiura, P.

1997-01-01

A wide range of general purpose high-energy physics applications, ranging from Monte Carlo simulation to data acquisition, from interactive data analysis to on-line filtering, have been ported, or developed, and run in parallel on IBM SP-2 and Meiko CS-2 CERN large multi-processor machines. The ESPRIT project GP-MIMD2 has been a catalyst for the interest in parallel computing at CERN. The project provided the 128 processor Meiko CS-2 system that is now succesfully integrated in the CERN computing environment. The CERN experiment NA48 was involved in the GP-MIMD2 project since the beginning. NA48 physicists run, as part of their day-to-day work, simulation and analysis programs parallelized using the message passing interface MPI. The CS-2 is also a vital component of the experiment data acquisition system and will be used to calibrate in real-time the 13000 channels liquid krypton calorimeter. (orig.)

The UK Human Genome Mapping Project online computing service.

Science.gov (United States)

Rysavy, F R; Bishop, M J; Gibbs, G P; Williams, G W

1992-04-01

This paper presents an overview of computing and networking facilities developed by the Medical Research Council to provide online computing support to the Human Genome Mapping Project (HGMP) in the UK. The facility is connected to a number of other computing facilities in various centres of genetics and molecular biology research excellence, either directly via high-speed links or through national and international wide-area networks. The paper describes the design and implementation of the current system, a 'client/server' network of Sun, IBM, DEC and Apple servers, gateways and workstations. A short outline of online computing services currently delivered by this system to the UK human genetics research community is also provided. More information about the services and their availability could be obtained by a direct approach to the UK HGMP-RC.

β4 systematics in rare-earth and actinide nuclei: sdg interacting boson model description

International Nuclear Information System (INIS)

Devi, Y.D.; Kota, V.K.B.

1992-01-01

The observed variation of hexadecupole deformation parameter β 4 with mass number A in rare-earth and actinide nuclei is studied in the sdg interacting boson model (IBM) using single j-shell Otsuka-Arima-Iachello mapped and IBM-2 to IBM-1 projected hexadecupole transition operator together with SU sdg (3) and SU sdg (5) coherent states. The SU sdg (3) limit is found to provide a good description of data

NetView technical research

Science.gov (United States)

1993-01-01

This is the Final Technical Report for the NetView Technical Research task. This report is prepared in accordance with Contract Data Requirements List (CDRL) item A002. NetView assistance was provided and details are presented under the following headings: NetView Management Systems (NMS) project tasks; WBAFB IBM 3090; WPAFB AMDAHL; WPAFB IBM 3084; Hill AFB; McClellan AFB AMDAHL; McClellan AFB IBM 3090; and Warner-Robins AFB.

Permitting of Landfill Bioreactor Operations: Ten Years after the RD&D Rule

Science.gov (United States)

Prior to promulgation of the Rule, there were approximately 20 full-scale bioreactor projects in North America, including one in Canada. Of these, six were permitted by EPA (four Project XL sites and two projects listed separately under a cooperative research agreement at the Ou...

FROM THE LEWIS AND CLARK EXPEDITION TO IBM, DELL, AND SOUTHWEST AIRLINES: TEACHING HISTORY AND LEADERSHIP TO BUSINESS STUDENTS

Directory of Open Access Journals (Sweden)

Jeffrey J. Matthews

2006-01-01

Full Text Available History is not a tomb of dead facts but a resource that can inform and improve everyday decision making. Experience as an analytical tool is invaluable for solving problems in changing and competitive environments. “From the Lewis and Clark Expedition,” which coincides with the National Lewis & Clark Bicentennial Commemoration (2003—2006, demonstrates how contemporary business concepts of visionary leadership, systematic planning, and organizational climate were instrumental to the success of Thomas Jefferson's “Corps of Discovery” and shows how a mastery of these concepts contributed to the successes of the pioneering US corporations IBM, Southwest Airlines, and Dell.

Numerical analysis of resonances induced by s wave neutrons in transmission time-of-flight experiments with a computer IBM 7094 II; Methodes d'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol et automatisation de ces methodes sur ordinateur IBM 7094 II

Energy Technology Data Exchange (ETDEWEB)

Corge, Ch. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1969-01-01

Numerical analysis of transmission resonances induced by s wave neutrons in time-of-flight experiments can be achieved in a fairly automatic way on an IBM 7094/II computer. The involved computations are carried out following a four step scheme: 1 - experimental raw data are processed to obtain the resonant transmissions, 2 - values of experimental quantities for each resonance are derived from the above transmissions, 3 - resonance parameters are determined using a least square method to solve the over determined system obtained by equalling theoretical functions to the correspondent experimental values. Four analysis methods are gathered in the same code, 4 - graphical control of the results is performed. (author) [French] L'automatisation, sur ordinateur IBM 7094/II, de l'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol a ete accomplie en la decomposant selon un schema articule en quatre phases: 1 - le traitement des donnees experimentales brutes pour obtenir les transmissions interfero-resonnantes, 2 - la determination des grandeurs d'analyse a partir des transmissions precedentes, 3 - l'analyse proprement dite des resonances dont les parametres sont obtenus par la resolution d'un systeme surabondant. Quatre methodes d'analyse sont groupees en un meme programme, 4 - la procedure de verification graphique. (auteur)

Computer Architecture for Energy Efficient SFQ

Science.gov (United States)

2014-08-27

IBM Corporation (T.J. Watson Research Laboratory) 1101 Kitchawan Road Yorktown Heights, NY 10598 -0000 2 ABSTRACT Number of Papers published in peer...accomplished during this ARO-sponsored project at IBM Research to identify and model an energy efficient SFQ-based computer architecture. The... IBM Windsor Blue (WB), illustrated schematically in Figure 2. The basic building block of WB is a "tile" comprised of a 64-bit arithmetic logic unit

RELAP5/MOD2 implementation on various mainframes including the IBM and SX-2 supercomputer

International Nuclear Information System (INIS)

DeForest, D.L.; Hassan, Y.A.

1987-01-01

The RELAP5/MOD2 (cycle 36.04) code is a one-dimensional, two-fluid, nonequilibrium, nonhomogeneous transient analysis code designed to simulate operational and accident scenarios in pressurized water reactors (PWRs). System models are solved using a semi-implicit finite difference method. The code was developed at EG and G in Idaho Falls under sponsorship of the US Nuclear Regulatory Commission (NRC). The major enhancement from RELAP5/MOD1 is the use of a six-equation, two-fluid nonequilibrium and nonhomogeneous model. Other improvements include the addition of a noncondensible gas component and the revision and addition of drag formulation, wall friction, and wall heat transfer. Several test cases were run to benchmark the IBM and SX-2 installations against the CDC computer and the CRAY-2 and CRAY/XMP. These included the Edward's pipe blow-down and two separate reflood cases developed to simulate the FLECHT-SEASET reflood test 31504 and a postcritical heat flux (CHF) test performed at Lehigh University

Theoretical aspects of neutron interaction: part 1 - interaction programme for ibm 7094, part 2 - the shielding sub-programme, part 3 - listing of the programme; Aspects theoriques de l'interaction neutronique: annexe 1 - programme interaction pour ibm 7094 - annexe 2 - sous programme ombre - annexe 3 - liste du programme

Energy Technology Data Exchange (ETDEWEB)

Moret-Bailly, J; Penet, F; Spinelli, J C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1965-07-01

Part I. Methods are described for obtaining the equations for a system of elements containing fissile matter: a) by using the balance after fission, b) by using the balance before fission, c) by the evolution equations. All these methods lead to equivalent matrices whose greatest proper value is the multiplication coefficient for the system K. It is shown how to calculate K. From this it is possible to deduce the rules which generalize the criterion for the bounded solid angle. An IBM 7094 programme applies this theory to the calculation of the installations made up of a maximum of 500 elements. It calculates the effective values of K, the leaks, the solid angles and then K. Part. II. This sub-programme calculates the shielding between the elements. (authors) [French] Sommaire, - Annexe I. On expose les methodes permettant d'obtenir les equations d'un systeme d'elements contenant de la matiere fissile: a) par le bilan apres fission, b) par le bilan avant fission, c) par les equations d'evolution. Toutes ces methodes conduisent a des matrices equivalentes dont la plus grande valeur propre est le coefficient de multiplication de l'ensemble K. On montre comment K se calcule. On en deduit des regles qui generalisent le critere de l'angle solide limite. Un programme pour IBM 7094 applique cette theorie au calcul des installations comportant au maximum 500 elements. II calcule les k effectifs, les fuites, les angles solides puis K. Annexe II. Ce sous-programme calcule les ombres entre les elements. (auteurs)

Simulation of the Mitra 15 micro-machine on IBM 360/91. Microprogramming of the fast Fourier transform

International Nuclear Information System (INIS)

Augustides, Jean

1973-01-01

As computing time did not allow working in real time, and as different methods had been proposed to reduce the computing time (the Cooley-Tuckey method, the use of specific FFT processors), this thesis proposes an intermediate solution, between the entirely programmed solution and the entirely cabled solution. After some generalities on micro-programming (definition, history, benefits and drawbacks, perspectives), the author reports the micro-programming of the Mitra 15 micro-machine: description of the machine, memory, command memory and associated circuits, interruptions and suspensions, descriptions of micro-statements, execution of a micro-statement. Programs and subroutines developed for the modelling of Mitra 15 micro-machine on IBM 360/91 are presented. Then, the author reports the micro-programming of the fast Fourier transform: theory, program description, and test

Solar energy system performance evaluation: Seasonal report for IBM system 1A, Huntsville, Alabama

Science.gov (United States)

1980-01-01

The operational and thermal performance of the solar energy system, Sims Prototype System 1A, is described. The system was designed by IBM to provide 50 to 60 percent of the space heating and domestic hot water preheating load to a 2,000 square foot floor space single family residence in the Huntsville area. The load design temperature inside the building was to be maintained at 70 degrees fahrenheit with auxiliary energy for heating supplied by an electric heat pump assisted by an electric resistance strip heater. In general the disappointing operation of this system is attributed to the manner in which it was used. The system was designed for residential application and used to satisfy the demands of an office environment. The differences were: (1) inside temperature was not maintained at 70 F as expected; and (2) hot water usage was much lower than expected. The conclusion is that the solar energy system must be designed for the type of application in which it is used. Misapplication usually will have an adverse affect on system performance.

Simple model for deriving sdg interacting boson model Hamiltonians: 150Nd example

Science.gov (United States)

Devi, Y. D.; Kota, V. K. B.

1993-07-01

A simple and yet useful model for deriving sdg interacting boson model (IBM) Hamiltonians is to assume that single-boson energies derive from identical particle (pp and nn) interactions and proton, neutron single-particle energies, and that the two-body matrix elements for bosons derive from pn interaction, with an IBM-2 to IBM-1 projection of the resulting p-n sdg IBM Hamiltonian. The applicability of this model in generating sdg IBM Hamiltonians is demonstrated, using a single-j-shell Otsuka-Arima-Iachello mapping of the quadrupole and hexadecupole operators in proton and neutron spaces separately and constructing a quadrupole-quadrupole plus hexadecupole-hexadecupole Hamiltonian in the analysis of the spectra, B(E2)'s, and E4 strength distribution in the example of 150Nd.

Simple model for deriving sdg interacting boson model Hamiltonians: 150Nd example

International Nuclear Information System (INIS)

Devi, Y.D.; Kota, V.K.B.

1993-01-01

A simple and yet useful model for deriving sdg interacting boson model (IBM) Hamiltonians is to assume that single-boson energies derive from identical particle (pp and nn) interactions and proton, neutron single-particle energies, and that the two-body matrix elements for bosons derive from pn interaction, with an IBM-2 to IBM-1 projection of the resulting p-n sdg IBM Hamiltonian. The applicability of this model in generating sdg IBM Hamiltonians is demonstrated, using a single-j-shell Otsuka-Arima-Iachello mapping of the quadrupole and hexadecupole operators in proton and neutron spaces separately and constructing a quadrupole-quadrupole plus hexadecupole-hexadecupole Hamiltonian in the analysis of the spectra, B(E2)'s, and E4 strength distribution in the example of 150 Nd

SPOOL-FIRE: an IBM 370/195 code for the analysis of combined spray and pool burning of sodium

International Nuclear Information System (INIS)

Charak, I.; Person, L.W.

1976-01-01

A code for the computation of the pressure and temperatures within a containment building as a result of a sodium fire is described. The fire is assumed to occur in two distinct phases: a spray and a pool. The spray fire is conservatively assumed to occur instantaneously. The pool fire model used is the SOFIRE-II model developed by Atomics International. The code calculates all important temperatures, accounting for heat loss from the building to the environment, as well as leakage of the containment atmosphere under conditions of internal overpressure. The IBM CSMP methodology is used to solve the set of ordinary differential equations which model the system. The use of CSMP allows the user considerable flexibility in modifying the models employed

Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL

Directory of Open Access Journals (Sweden)

Han Seol

2011-07-01

Full Text Available Abstract Background At the beginning of neurogenesis, massive brain cell death occurs and more than 50% of cells are eliminated by apoptosis along with neuronal differentiation. However, few studies were conducted so far regarding the regulation of neural progenitor cells (NPCs death during development. Because of the physiological role of cell death during development, aberration of normal apoptotic cell death is detrimental to normal organogenesis. Apoptosis occurs in not only neuron but also in NPCs and neuroblast. When growth and survival signals such as EGF or LIF are removed, apoptosis is activated as well as the induction of differentiation. To investigate the regulation of cell death during developmental stage, it is essential to investigate the regulation of apoptosis of NPCs. Methods Neural progenitor cells were cultured from E14 embryonic brains of Sprague-Dawley rats. For in vivo VPA animal model, pregnant rats were treated with VPA (400 mg/kg S.C. diluted with normal saline at E12. To analyze the cell death, we performed PI staining and PARP and caspase-3 cleavage assay. Expression level of proteins was investigated by Western blot and immunocytochemical assays. The level of mRNA expression was investigated by RT-PCR. Interaction of Bcl-XL gene promoter and NF-κB p65 was investigated by ChIP assay. Results In this study, FACS analysis, PI staining and PARP and caspase-3 cleavage assay showed that VPA protects cultured NPCs from cell death after growth factor withdrawal both in basal and staurosporine- or hydrogen peroxide-stimulated conditions. The protective effect of prenatally injected VPA was also observed in E16 embryonic brain. Treatment of VPA decreased the level of IκBα and increased the nuclear translocation of NF-κB, which subsequently enhanced expression of anti-apoptotic protein Bcl-XL. Conclusion To the best of our knowledge, this is the first report to indicate the reduced death of NPCs by VPA at developmentally

Possibilities and prospects of investigation of irradiated structural and fuel materials using scanning electron microscope PHILLIPS XL 30 ESEM-TMP installed in the hot cell

International Nuclear Information System (INIS)

Golovanov, V. N.; Novoselov, A.E.; Kuzmin, S.V.; Yakovlev, V. V.

2005-01-01

Scanning electron microscope Philips XL 30 ESEM - TMP with X-ray microanalysis system INCA has been installed at SSC RF RIAR. The microscope is placed in the hot cell. Monitoring and control system is installed in the operator's room. Irradiated specimens are supplied to the hot cell through the transport terminal and installed into the microscope by manipulators. Direct contact of the personnel with radioactive materials is impossible. In addition it is developed the system of remote placement of the irradiated specimens into the specimen chamber of microscope. The system includes a stage with three seats, holders for different types of specimens and equipment for their remote loading in the holders. (Author)

January: IBM 7094 programme for the resolution of cell problems in planar, spherical and cylindrical geometry using the double Pn approximation

International Nuclear Information System (INIS)

Amouyal, A.; Tariel, H.

1966-01-01

Code name: January 1 st SCEA 011S. 2) Computer: IBM 7094; Programme system: Fortran II, 2 nd version. 3) Nature of the problem: resolution of cell problems with one space variable (planar, spherical and cylindrical geometries) and with one energy group, with isotropic sources in the double P n approximation (DP 1 and DP 3 approximation in planar and spherical geometries, DP 1 and DP 2 in cylindrical geometry). 4) Method used: the differential equations with limiting conditions are transformed into differential system with initial conditions which are integrated by a separate-step method. 5) Restrictions: number of physical media [fr

Multiple uses for an old ibm-pc 486 in nuclear medicine using open source software

International Nuclear Information System (INIS)

Anselmi, C.E.; Anselmi, O.E.

2002-01-01

Multiple uses for an old ibm-pc 486 in nuclear medicine using open source software. Aim: To use a low budget platform to: 1 - send patient's images from processing workstation to the nuclear medicine information system; 2 - backup data files from acquisition in DICOM format in cd-rom; 3 - move data across different hospitals allowing remote processing and reading of studies. Both nuclear medicine systems in the two hospitals are Siemens Icon workstations. Material and methods: The computer used is an ibm-pc 486, which sells for about US dollar 70. The operating system installed is Red Hat Linux 6.2. The sending of the patient's images to the information system is performed through AppleTalk and Samba. The backup of acquisition files is performed by the communication from the workstation through DICOM to the Storage Class Provider (Office Dicom Toolkit) running in the 486, and the files are later burned on cd-rom. A similar configuration is present in another hospital, with minor differences in processor type. Data from any of the hospitals can be sent to the other one through the remote synchronization performed by Rsync. The connection between both Linux computers is encrypted through Secure Shell (open SSH). All software installed in the 486 was downloaded from the internet at no cost. No software was installed in the workstations. Results: The whole system is recognized transparently by the workstation's system as a local storage disk, such as the acquisition cameras or the other workstations. The transfer of images from the workstation to the information system or to a remote hospital is done the same way as copying data from the acquisition cameras in the vendor's software. When transferring large files across hospitals, the synchronization may take 1 to 3 minutes through broad band internet. The backup in DICOM format in cd-rom allows review of patient data in any computer equipped with a DICOM viewing software, as well as the re-processing of that

Hf-Nd Isotopes in West Philippine Basin Basalts: Results from International Ocean Discovery Program (IODP) Site U1438 and Implications for the Early History of the Izu-Bonin-Mariana (IBM) Subduction System

Science.gov (United States)

Yogodzinski, G. M.; Hocking, B.; Bizimis, M.; Hickey-Vargas, R.; Ishizuka, O.; Bogus, K.; Arculus, R. J.

2015-12-01

Drilling at IODP Site U1438, located immediately west of Kyushu-Palau Ridge (KPR), the site of IBM subduction initiation, penetrated 1460 m of volcaniclastic sedimentary rock and 150 m of underlying basement. Biostratigraphic controls indicate a probable age for the oldest sedimentary rocks at around 55 Ma (51-64 Ma - Arculus et al., Nat Geosci in-press). This is close to the 48-52 Ma time period of IBM subduction initiation, based on studies in the forearc. There, the first products of volcanism are tholeiitic basalts termed FAB (forearc basalt), which are more depleted than average MORB and show subtle indicators of subduction geochemical enrichment (Reagan et al., 2010 - Geochem Geophy Geosy). Shipboard data indicate that Site U1438 basement basalts share many characteristics with FABs, including primitive major elements (high MgO/FeO*) and strongly depleted incompatible element patterns (Ti, Zr, Ti/V and Zr/Y below those of average MORB). Initial results thus indicate that FAB geochemistry may have been produced not only in the forearc, but also in backarc locations (west of the KPR) at the time of subduction initiation. Hf-Nd isotopes for Site 1438 basement basalts show a significant range of compositions from ɛNd of 7.0 to 9.5 and ɛHf of 14.5 to 19.8 (present-day values). The data define a well-correlated and steep array in Hf-Nd isotope space. Relatively radiogenic Hf compared to Nd indicates an Indian Ocean-type MORB source, but the dominant signature, with ɛHf >16.5, is more radiogenic than most Indian MORB. The pattern through time is from more-to-less radiogenic and more variable Hf-Nd isotopes within the basement section. This pattern culminates in basaltic andesite sills, which intrude the lower parts of the sedimentary section. The sills have the least radiogenic compositions measured so far (ɛNd ~6.6, ɛHf ~13.8), and are similar to those of boninites of the IBM forearc and modern IBM arc and reararc rocks. The pattern within the basement

User's guide to a data base of current environmental monitoring projects in the US-Canadian transboundary region

Energy Technology Data Exchange (ETDEWEB)

Ballinger, M.Y.; Defferding, J.; Chapman, E.G.; Bettinson, M.D.; Glantz, C.S.

1987-11-01

This document describes how to use a data base of current transboundary region environmental monitoring projects. The data base was prepared from data provided by Glantz et al. (1986) and Concord Scientific Corporation (1985), and contains information on 226 projects with monitoring stations located within 400 km (250 mi) of the US-Canadian border. The data base is designed for use with the dBASE III PLUS data management systems on IBM-compatible personal computers. Data-base searches are best accomplished using an accompanying command file called RETRIEVE or the dBASE command LIST. The user must carefully select the substrings on which the search is to be based. Example search requests and subsequent output are presented to illustrate substring selections and applications of the data base. 4 refs., 15 figs., 4 tabs.

Direct visualization of in vitro drug mobilization from Lescol XL tablets using two-dimensional (19)F and (1)H magnetic resonance imaging.

Science.gov (United States)

Chen, Chen; Gladden, Lynn F; Mantle, Michael D

2014-02-03

This article reports the application of in vitro multinuclear ((19)F and (1)H) two-dimensional magnetic resonance imaging (MRI) to study both dissolution media ingress and drug egress from a commercial Lescol XL extended release tablet in a United States Pharmacopeia Type IV (USP-IV) dissolution cell under pharmacopoeial conditions. Noninvasive spatial maps of tablet swelling and dissolution, as well as the mobilization and distribution of the drug are quantified and visualized. Two-dimensional active pharmaceutical ingredient (API) mobilization and distribution maps were obtained via (19)F MRI. (19)F API maps were coregistered with (1)H T2-relaxation time maps enabling the simultaneous visualization of drug distribution and gel layer dynamics within the swollen tablet. The behavior of the MRI data is also discussed in terms of its relationship to the UV drug release behavior.

Astra data base server: system specifications

OpenAIRE

Abba, Laura; Cecaloni, Patrizia; Romano, Giuseppe Alberto; Vannozzi, Daniele

1990-01-01

We describe a system intended to access databases distributed on EARN network. Thus system has been developed at CNUCE by the ASTRA project team. The service started, in test mode, january 1, 1989. The first version accessed the IBM study contracts database and other italian databases located on the EARN network. The databases were managed an IBM information retrieval system of IBM named STAIRS/CMS. Afterwards we deciced to interface some other I.R.S systems and a DataBase Management system b...

FASTRAN II - FATIGUE CRACK GROWTH STRUCTURAL ANALYSIS (IBM PC VERSION)

Science.gov (United States)

Newman, J. C.

1994-01-01

loads may be either tensile or compressive. Several standardized aircraft flight-load histories, such as TWIST, Mini-TWIST, FALSTAFF, Inverted FALSTAFF, Felix and Gaussian, are included as options. FASTRAN II also includes two other methods that will help the user input spectrum load histories. The two methods are: (1) a list of stress points, and (2) a flight-by-flight history of stress points. Examples are provided in the user manual. Developed as a research program, FASTRAN II has successfully predicted crack growth in many metallic materials under various aircraft spectrum loading. A computer program DKEFF which is a part of the FASTRAN II package was also developed to analyze crack growth rate data from laboratory specimens to obtain the effective stress-intensity factor against crack growth rate relations used in FASTRAN II. FASTRAN II is written in standard FORTRAN 77. It has been successfully compiled and implemented on Sun4 series computers running SunOS and on IBM PC compatibles running MS-DOS using the Lahey F77L FORTRAN compiler. Sample input and output data are included with the FASTRAN II package. The UNIX version requires 660K of RAM for execution. The standard distribution medium for the UNIX version (LAR-14865) is a .25 inch streaming magnetic tape cartridge in UNIX tar format. It is also available on a 3.5 inch diskette in UNIX tar format. The standard distribution medium for the MS-DOS version (LAR-14944) is a 5.25 inch 360K MS-DOS format diskette. The contents of the diskette are compressed using the PKWARE archiving tools. The utility to unarchive the files, PKUNZIP.EXE, is included. The program was developed in 1984 and revised in 1992. Sun4 and SunOS are trademarks of Sun Microsystems, Inc. IBM PC is a trademark of International Business Machines Corp. MS-DOS is a trademark of Microsoft, Inc. F77L is a trademark of the Lahey Computer Systems, Inc. UNIX is a registered trademark of AT&T Bell Laboratories. PKWARE and PKUNZIP are trademarks of PKWare

Geochemistry of Volcanic Rocks from International Ocean Discovery Program (IODP) Site 1438, Amami Sankaku Basin: Implications for Izu-Bonin-Mariana (IBM) Arc Initiation

Science.gov (United States)

Hickey-Vargas, R.; Ishizuka, O.; Yogodzinski, G. M.; Bizimis, M.; Savov, I. P.; McCarthy, A. J.; Arculus, R. J.; Bogus, K.

2015-12-01

IODP Expedition 351 drilled 150 m of volcanic basement overlain by 1461 m of sedimentary material at Site 1438 in the Amami Sankaku basin, just west of the Kyushu Palau Ridge, the locus of IBM arc initiation. Age interpretations based on biostratigraphy (Arculus et al., Nat. Geosci., in-press) determined that the age of the basement section is between 64 and 51 Ma, encompassing the age of the earliest volcanic products of the IBM arc. The Site 1438 volcanic basement consists of multiple flows of aphyric microcrystalline to finely crystalline basalts containing plagioclase and clinopyroxene with rare olivine pseudomorphs. New XRF major and ICPMS trace element data confirm findings of shipboard analysis that the basalts are moderately differentiated (6-14 % MgO; Mg# = 51-83; 73-490 ppm Cr and 58-350 ppm Ni) with downcore variations related to flow units. Ti/V and Ti/Sc ratios are 16-27 and 75-152, respectively, with lowest values at the base of the core. One prominent characteristic of the basalts is their depletion of immobile highly incompatible elements compared with MORB. Basalts have MORB-normalized La/Nd of 0.5 to 0.9, and most have Th/La 3 and primitive mantle normalized La/Yb > 1. Our results suggest that mantle melting at the onset of subduction involved exceptionally depleted sources. Enrichment over time may be related to increasing subduction inputs and/or other processes, such as entrainment of fertile asthenosphere during extension of the overriding plate.

Effect of fabrication pressure on the fatigue performance of Cemex XL acrylic bone cement.

Science.gov (United States)

Lewis, Gladius; Janna, S I

2004-01-01

During a cemented arthroplasty, the prepared polymerizing dough of acrylic bone cement is subjected to pressurization in a number of ways; first, during delivery into the freshly prepared bone bed, second, during packing in that bed (either digitally or with the aid of a mechanical device), and, third, during the insertion of the prosthesis. Only a few studies have reported on the influence of the level of pressurization experienced during these events (which, depending on the cementing technique used, has been put at between 8 and 273 kPa) on various properties of the cement. That was the focus of the present study, in which the fully reversed tension-compression (+/-15 MPa; 5 Hz) fatigue lives (expressed as number of cycles to fracture, N(f)) of rectangular cross-sectioned "dog-bone" specimens (Type V, per ASTM D 638) fabricated from Cemex XL cement, at pressure applied continuously to the cement dough during curing in the specimen mold, p=75,150, and 300 kPa, were determined. The N(f) results were analyzed using the linearized transformation of the three-parameter Weibull relationship to obtain estimates of the Weibull mean, N(WM), which was taken to be the index of fatigue performance of the specimen set. Over the range of p studied, N(WM) increased as p increased (for example, from 329,118 cycles when p was 75 kPa to 388,496 cycles when p was 300 kPa); however, the increase was not significant over any pair of p increment steps (Mann-Whitney U-test; alpha<0.05).

Automated IBM PC/XT/AT based measurement and control system for the DRON-3M X-ray diffractometer

International Nuclear Information System (INIS)

Tulaev, A.B.

1989-01-01

An automated IBM PC/XT/AT based measurement and control system for the DRON-3M X-ray diffractometer is decribed. The system permits carrying out of real time diffractometer control automatic X-spectra measurement and data acquisition, as well as experimental information computing and representation. The electronic of the system consists of a CAMAC crate with analog and power modules, and a control and measurement organization module, performed as a single bord in the standard of PC electronics. The system provides X-spectra acquisition with volume up to 4K in the angle range from 100 to 160 degrees with a resolution of 0.01 degree, a dead time less than 1mks and an exposition time from tenths of a second to dozens of minutes. 3 refs.; 5 figs

Innovative approach for restoring coastal wetlands using treated drill cuttings

International Nuclear Information System (INIS)

Veil, J. A.; Hocking, E. K.

1999-01-01

The leading environmental problem facing coastal Louisiana regions is the loss of wetlands. Oil and gas exploration and production activities have contributed to wetland damage through erosion at numerous sites where canals have been cut through the marsh to access drilling sites. An independent oil and gas producer, working with Southeastern Louisiana University and two oil field service companies, developed a process to stabilize drill cuttings so that they could be used as a substrate to grow wetlands vegetation. The U.S. Department of Energy (DOE) funded a project under which the process would be validated through laboratory studies and field demonstrations. The laboratory studies demonstrated that treated drill cuttings support the growth of wetlands vegetation. However, neither the Army Corps of Engineers (COE) nor the U.S. Environmental Protection Agency (EPA) would grant regulatory approval for afield trial of the process. Argonne National Laboratory was asked to join the project team to try to find alternative mechanisms for gaining regulatory approval. Argonne worked with EPA's Office of Reinvention and learned that EPA's Project XL would be the only regulatory program under which the proposed field trial could be done. One of the main criteria for an acceptable Project XL proposal is to have a formal project sponsor assume the responsibility and liability for the project. Because the proposed project involved access to private land areas, the team felt that an oil and gas company with coastal Louisiana land holdings would need to serve as sponsor. Despite extensive communication with oil and gas companies and industry associations, the project team was unable to find any organization willing to serve as sponsor. In September 1999, the Project XL proposal was withdrawn and the project was canceled

Survivability enhancement study for C/sup 3/I/BM (communications, command, control and intelligence/battle management) ground segments: Final report

Energy Technology Data Exchange (ETDEWEB)

1986-10-30

This study involves a concept developed by the Fairchild Space Company which is directly applicable to the Strategic Defense Initiative (SDI) Program as well as other national security programs requiring reliable, secure and survivable telecommunications systems. The overall objective of this study program was to determine the feasibility of combining and integrating long-lived, compact, autonomous isotope power sources with fiber optic and other types of ground segments of the SDI communications, command, control and intelligence/battle management (C/sup 3/I/BM) system in order to significantly enhance the survivability of those critical systems, especially against the potential threats of electromagnetic pulse(s) (EMP) resulting from high altitude nuclear weapon explosion(s). 28 figs., 2 tabs.

Gene Expression of Lytic Endopeptidases AlpA and AlpB from Lysobacter sp. XL1 in Pseudomonads.

Science.gov (United States)

Tsfasman, Irina M; Lapteva, Yulia S; Krasovskaya, Ludmila A; Kudryakova, Irina V; Vasilyeva, Natalia V; Granovsky, Igor E; Stepnaya, Olga A

2015-01-01

Development of an efficient expression system for (especially secreted) bacterial lytic enzymes is a complicated task due to the specificity of their action. The substrate for such enzymes is peptidoglycan, the main structural component of bacterial cell walls. For this reason, expression of recombinant lytic proteins is often accompanied with lysis of the producing bacterium. This paper presents data on the construction of an inducible system for expression of the lytic peptidases AlpA and AlpB from Lysobacter sp. XL1 in Pseudomonas fluorescens Q2-87, which provides for the successful secretion of these proteins into the culture liquid. In this system, the endopeptidase gene under control of the T7lac promoter was integrated into the bacterial chromosome, as well as the Escherichia coli lactose operon repressor protein gene. The T7 pol gene under lac promoter control, which encodes the phage T7 RNA polymerase, is maintained in Pseudomonas cells on the plasmids. Media and cultivation conditions for the recombinant strains were selected to enable the production of AlpA and AlpB by a simple purification protocol. Production of recombinant lytic enzymes should contribute to the development of new-generation antimicrobial drugs whose application will not be accompanied by selection of resistant microorganisms. © 2015 S. Karger AG, Basel.

Numerical analysis of resonances induced by s wave neutrons in transmission time-of-flight experiments with a computer IBM 7094 II

International Nuclear Information System (INIS)

Corge, Ch.

1969-01-01

Numerical analysis of transmission resonances induced by s wave neutrons in time-of-flight experiments can be achieved in a fairly automatic way on an IBM 7094/II computer. The involved computations are carried out following a four step scheme: 1 - experimental raw data are processed to obtain the resonant transmissions, 2 - values of experimental quantities for each resonance are derived from the above transmissions, 3 - resonance parameters are determined using a least square method to solve the over determined system obtained by equalling theoretical functions to the correspondent experimental values. Four analysis methods are gathered in the same code, 4 - graphical control of the results is performed. (author) [fr

Elementary Technology Demonstration Schools: The Third Year 1992-93. Publication Number 92.31.

Science.gov (United States)

Sabatino, Melissa

The 1992-93 school year was the third year of the Elementary Technology Demonstration Schools program of the Austin (Texas) schools; the project is funded by International Business Machines Corporation (IBM) and Apple Computer Inc. Grants from these corporations were used to equip three elementary schools with IBM equipment and one with Apple…

Procedures to analyse γ-ray spectra obtained from the ORTEC or nuclear data ND-680 system by ORTEC's analysis software packages incorporated into a separate IBM-PC computer

International Nuclear Information System (INIS)

Zhang Xiu Zhen.

1990-01-01

A detailed description is presented for processing γ-spectra produced by means of Ortec or Nuclear Data spectrometry systems on an off-line IBM-PC. The ORTEC analysis software packages were transferred to and implemented on the PC A/T, and the different spectra were recorded on discs and subsequently brought into the format required by the program for the calculation of photo peak areas. (author)

Case Study: IBM Watson Analytics Cloud Platform as Analytics-as-a-Service System for Heart Failure Early Detection

Directory of Open Access Journals (Sweden)

Gabriele Guidi

2016-07-01

Full Text Available In the recent years the progress in technology and the increasing availability of fast connections have produced a migration of functionalities in Information Technologies services, from static servers to distributed technologies. This article describes the main tools available on the market to perform Analytics as a Service (AaaS using a cloud platform. It is also described a use case of IBM Watson Analytics, a cloud system for data analytics, applied to the following research scope: detecting the presence or absence of Heart Failure disease using nothing more than the electrocardiographic signal, in particular through the analysis of Heart Rate Variability. The obtained results are comparable with those coming from the literature, in terms of accuracy and predictive power. Advantages and drawbacks of cloud versus static approaches are discussed in the last sections.

Demonstration of Autonomous Rendezvous Technology (DART) Project Summary

Science.gov (United States)

Rumford, TImothy E.

2003-01-01

Since the 1960's, NASA has performed numerous rendezvous and docking missions. The common element of all US rendezvous and docking is that the spacecraft has always been piloted by astronauts. Only the Russian Space Program has developed and demonstrated an autonomous capability. The Demonstration of Autonomous Rendezvous Technology (DART) project currently funded under NASA's Space Launch Initiative (SLI) Cycle I, provides a key step in establishing an autonomous rendezvous capability for the United States. DART's objective is to demonstrate, in space, the hardware and software necessary for autonomous rendezvous. Orbital Sciences Corporation intends to integrate an Advanced Video Guidance Sensor and Autonomous Rendezvous and Proximity Operations algorithms into a Pegasus upper stage in order to demonstrate the capability to autonomously rendezvous with a target currently in orbit. The DART mission will occur in April 2004. The launch site will be Vandenburg AFB and the launch vehicle will be a Pegasus XL equipped with a Hydrazine Auxiliary Propulsion System 4th stage. All mission objectives will be completed within a 24 hour period. The paper provides a summary of mission objectives, mission overview and a discussion on the design features of the chase and target vehicles.

Classic Multi-Configuration-Dirac-Fock and Hartree-Fock-Relativistic methods integrated into a program package for the RAL-IBM mainframe with automatic comparative output

International Nuclear Information System (INIS)

Cowan, R.D.; Grant, I.P.; Fawcett, B.C.; Rose, S.J.

1985-11-01

A Multi-Configuration-Dirac-Fock (MCDF) computer program is adapted to interface with the Hartree-Fock-Relativistic (HFR) program for the RAL IBM mainframe computer. The two codes are integrated into a package which includes the Zeeman Laboratory Slater parameter optimisation routines as well as new RAL routines to further process the HFR and MCDF output. A description of the adaptions to MCDF and new output extensions is included in this report, and details are given regarding HFR FORTRAN subroutines, and lists of Job Control Language (JCL) files for the complete package. (author)

Semantic eScience for Ecosystem Understanding and Monitoring: The Jefferson Project Case Study

Science.gov (United States)

McGuinness, D. L.; Pinheiro da Silva, P.; Patton, E. W.; Chastain, K.

2014-12-01

Monitoring and understanding ecosystems such as lakes and their watersheds is becoming increasingly important. Accelerated eutrophication threatens our drinking water sources. Many believe that the use of nutrients (e.g., road salts, fertilizers, etc.) near these sources may have negative impacts on animal and plant populations and water quality although it is unclear how to best balance broad community needs. The Jefferson Project is a joint effort between RPI, IBM and the Fund for Lake George aimed at creating an instrumented water ecosystem along with an appropriate cyberinfrastructure that can serve as a global model for ecosystem monitoring, exploration, understanding, and prediction. One goal is to help communities understand the potential impacts of actions such as road salting strategies so that they can make appropriate informed recommendations that serve broad community needs. Our semantic eScience team is creating a semantic infrastructure to support data integration and analysis to help trained scientists as well as the general public to better understand the lake today, and explore potential future scenarios. We are leveraging our RPI Tetherless World Semantic Web methodology that provides an agile process for describing use cases, identification of appropriate background ontologies and technologies, implementation, and evaluation. IBM is providing a state-of-the-art sensor network infrastructure along with a collection of tools to share, maintain, analyze and visualize the network data. In the context of this sensor infrastructure, we will discuss our semantic approach's contributions in three knowledge representation and reasoning areas: (a) human interventions on the deployment and maintenance of local sensor networks including the scientific knowledge to decide how and where sensors are deployed; (b) integration, interpretation and management of data coming from external sources used to complement the project's models; and (c) knowledge about

Measurement stand for diagnosis of semiconductor detectors based on IBM PC/XT computer (4-way spectrometric analysis of pulses)

International Nuclear Information System (INIS)

Gruszecki, M.

1990-01-01

The technical assumptions and partial realization of our technological stand for quality inspection of semiconductor detectors for ionizing radiation manufactured in the INP in Cracow are described. To increase the efficiency of the measurements simultaneous checking of 4 semiconductor chips or finished products is suggested. In order to justify this measurement technique a review of possible variants of the measurement apparatus is presented for the systems consisting of home made units. Comparative parameters for the component modules and for complete measuring systems are given. The construction and operation of data acquisition system based on IBM PC/XT are described. The system ensures simultaneous registration of pulses obtained from 4 detectors with maximal rate of up to 500 x 10 3 pulses/s. 42 refs., 6 figs., 3 tabs. (author)

Outline of ATE Novoronezh Training Centre simulator V-187 upgrade project

International Nuclear Information System (INIS)

2006-01-01

Full-scope simulator V-187 was put into operation in 1987. Novovoronezh NPP Unit 5 is the reference unit for the simulator. The following is included into the simulator computer engineering: - central computer IBM 4381 to calculate the simulator mathematical models and to maintain the Instructor's Workstation; - 2 computers CM-2M to control the graphical information display subsystem; - 3 computers (object link computing terminal) to control the analog and discrete information input-output; - specially designed devices of discrete information compression to connect OLCT computers with control panel; - alpha-digital display of IBM 4381 computer is used as Instructor's Work-station. Computer languages: FORTRAN, Assembler

A microprocessor card software server to support the Quebec health microprocessor card project.

Science.gov (United States)

Durant, P; Bérubé, J; Lavoie, G; Gamache, A; Ardouin, P; Papillon, M J; Fortin, J P

1995-01-01

The Quebec Health Smart Card Project is advocating the use of a memory card software server[1] (SCAM) to implement a portable medical record (PMR) on a smart card. The PMR is viewed as an object that can be manipulated by SCAM's services. In fact, we can talk about a pseudo-object-oriented approach. This software architecture provides a flexible and evolutive way to manage and optimize the PMR. SCAM is a generic software server; it can manage smart cards as well as optical (laser) cards or other types of memory cards. But, in the specific case of the Quebec Health Card Project, SCAM is used to provide services between physicians' or pharmacists' software and IBM smart card technology. We propose to expose the concepts and techniques used to provide a generic environment to deal with smart cards (and more generally with memory cards), to obtain a dynamic an evolutive PMR, to raise the system global security level and the data integrity, to optimize significantly the management of the PMR, and to provide statistic information about the use of the PMR.

Lateritinga project: a geochemical orientation study for Amazon lateritic

International Nuclear Information System (INIS)

Costa, M.L. da

1990-01-01

The aim of this project is the development of systematic geochemical orientation survey in lateritic weathered terrain, like those form Amazon Region. The main selected targets (sheets) are: Turiacu, Cajuapara and Serra dos Carajas, with 690 samples collected (soils and lateritic rocks). For the Aurizona-Serra do Pirocaua target (Turiacu sheet), within the purpose of this work, 49 samples were collected in a 100x 200m regular grid. From all samples the fraction minor than 200 mesh was taken to analyses (by XRF, AA, OES, ICP and fire assay) for SiO sub(2), Fe sub(2) O sub(3), TiO sub(2), P sub(2) O sub(5), Sr, Ba, Y, Nb, Zr, Ga, Sc, Ni, Co, Cr, Cu, Mn, V, As, Bi, Pt, Pd, Th, Au and REE, as well for their mineralogy by XRD. The chemical results were submitted to statistical treatment with the Geoquant-software for IBM-compatible microcomputer. (author)

Overview of the ATLAS Insertable B-Layer (IBL) Project

CERN Document Server

Kagan, M; The ATLAS collaboration

2014-01-01

The first upgrade for the Pixel Detector will be a new pixel layer which is currently under construction and will be installed during the first shutdown of the LHC machine, in 2013-14. The new detector, called the Insertable B-layer (IBL), will be installed between the existing Pixel Detector and a new, smaller radius beam-pipe. Two different silicon sensor technologies, planar n-in-n and 3D, will be used, connected with the new generation 130nm IBM CMOS FE-I4 readout chip via solder bump-bonds. A production quality control test bench was setup in the ATLAS inner detector assembly clean room to verify and rate the performance of the detector elements before integration around the beam pipe. An overview of the IBL project, of the module design, the qualification for these sensor technologies, the integration quality control setups and recent results in the construction of this full scale new concept detector is discussed.

Overview of the ATLAS Insertable B-Layer (IBL) Project

Science.gov (United States)

Kagan, M. A.

2014-06-01

The first upgrade for the Pixel Detector will be a new pixel layer which is currently under construction and will be installed during the first shutdown of the LHC machine, in 2013-14. The new detector, called the Insertable B-layer (IBL), will be installed between the existing Pixel Detector and a new, smaller radius beam-pipe. Two different silicon sensor technologies, planar n-in-n and 3D, will be used, connected with the new generation 130nm IBM CMOS FE-I4 readout chip via solder bump-bonds. A production quality control test bench was set up in the ATLAS inner detector assembly clean room to verify and rate the performance of the detector elements before integration around the beam-pipe. An overview of the IBL project, of the module design, the qualification for these sensor technologies, the integration quality control setups and recent results in the construction of this full scale new concept detector is discussed.

Hemorrhagic Stroke in a Young Healthy Male Following Use of Pre-Workout Supplement Animal Rage XL.

Science.gov (United States)

Harris, Brandon F; Winn, Coty; Ableman, Thomas B

2017-09-01

So-called "pre-workout" supplements are substances marketed as natural dietary supplements with claims of helping athletes achieve more focused and intense workouts. The use of such products remains popular among American youth as a whole, but is especially high among active duty service members. Supplements are minimally regulated by the Food and Drug Administration (FDA), and unlike pharmaceuticals, supplements are often brought to market without any testing to show neither efficacy nor safety. Several case reports have documented serious adverse events and raise the question of whether supplement use was a causative factor. Reported events occurring after use of pre-workout supplements include, among others, ischemic stroke, hemorrhagic stroke, myocardial infarction, hepatitis, and death. Here, we present the case of a healthy 25-year-old active duty male who experienced a bilateral cerebellar hemorrhagic stroke occurring shortly after taking a supplement named Animal Rage XL. Hemorrhagic stroke occurring in a healthy 25-year-old male with no risk factors is exceedingly rare. This is the first known case of stroke temporally associated with this particular supplement, which is currently available for purchase at military exchanges. Additionally, several of the active ingredients in this supplement have been shown to cause hypertension, tachycardia, and vasospasm. All of these effects could increase the likelihood and severity of a hemorrhagic stroke. The investigated ingredients in this abstract include β-phenethylamine, creatine-monophosphate, and caffeine. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS]).

Science.gov (United States)

Mahmood, Abda; Roberts, Ian; Shakur, Haleema

2017-07-17

Tranexamic acid prevents blood clots from breaking down and reduces bleeding. However, it is uncertain whether tranexamic acid is effective in traumatic brain injury. The CRASH-3 trial is a randomised controlled trial that will examine the effect of tranexamic acid (versus placebo) on death and disability in 13,000 patients with traumatic brain injury. The CRASH-3 trial hypothesizes that tranexamic acid will reduce intracranial haemorrhage, which will reduce the risk of death. Although it is possible that tranexamic acid will reduce intracranial bleeding, there is also a potential for harm. In particular, tranexamic acid may increase the risk of cerebral thrombosis and ischaemia. The protocol detailed here is for a mechanistic sub-study nested within the CRASH-3 trial. This mechanistic sub-study aims to examine the effect of tranexamic acid (versus placebo) on intracranial bleeding and cerebral ischaemia. The CRASH-3 Intracranial Bleeding Mechanistic Sub-Study (CRASH-3 IBMS) is nested within a prospective, double-blind, multi-centre, parallel-arm randomised trial called the CRASH-3 trial. The CRASH-3 IBMS will be conducted in a cohort of approximately 1000 isolated traumatic brain injury patients enrolled in the CRASH-3 trial. In the CRASH-3 IBMS, brain scans acquired before and after randomisation are examined, using validated methods, for evidence of intracranial bleeding and cerebral ischaemia. The primary outcome is the total volume of intracranial bleeding measured on computed tomography after randomisation, adjusting for baseline bleeding volume. Secondary outcomes include progression of intracranial haemorrhage (from pre- to post-randomisation scans), new intracranial haemorrhage (seen on post- but not pre-randomisation scans), intracranial haemorrhage following neurosurgery, and new focal ischaemic lesions (seen on post-but not pre-randomisation scans). A linear regression model will examine whether receipt of the trial treatment can predict haemorrhage

F-16XL Hybrid Reynolds-Averaged Navier-Stokes/Large Eddy Simulation on Unstructured Grids

Science.gov (United States)

Park, Michael A.; Abdol-Hamid, Khaled S.; Elmiligui, Alaa

2015-01-01

This study continues the Cranked Arrow Wing Aerodynamics Program, International (CAWAPI) investigation with the FUN3D and USM3D flow solvers. CAWAPI was established to study the F-16XL, because it provides a unique opportunity to fuse fight test, wind tunnel test, and simulation to understand the aerodynamic features of swept wings. The high-lift performance of the cranked-arrow wing planform is critical for recent and past supersonic transport design concepts. Simulations of the low speed high angle of attack Flight Condition 25 are compared: Detached Eddy Simulation (DES), Modi ed Delayed Detached Eddy Simulation (MDDES), and the Spalart-Allmaras (SA) RANS model. Iso- surfaces of Q criterion show the development of coherent primary and secondary vortices on the upper surface of the wing that spiral, burst, and commingle. SA produces higher pressure peaks nearer to the leading-edge of the wing than flight test measurements. Mean DES and MDDES pressures better predict the flight test measurements, especially on the outer wing section. Vorticies and vortex-vortex interaction impact unsteady surface pressures. USM3D showed many sharp tones in volume points spectra near the wing apex with low broadband noise and FUN3D showed more broadband noise with weaker tones. Spectra of the volume points near the outer wing leading-edge was primarily broadband for both codes. Without unsteady flight measurements, the flight pressure environment can not be used to validate the simulations containing tonal or broadband spectra. Mean forces and moment are very similar between FUN3D models and between USM3D models. Spectra of the unsteady forces and moment are broadband with a few sharp peaks for USM3D.

Integrating Biodiversity into Biosphere-Atmosphere Interactions Using Individual-Based Models (IBM)

Science.gov (United States)

Wang, B.; Shugart, H. H., Jr.; Lerdau, M.

2017-12-01

A key component regulating complex, nonlinear, and dynamic biosphere-atmosphere interactions is the inherent diversity of biological systems. The model frameworks currently widely used, i.e., Plant Functional Type models) do not even begin to capture the metabolic and taxonomic diversity found in many terrestrial systems. We propose that a transition from PFT-based to individual-based modeling approaches (hereafter referred to as IBM) is essential for integrating biodiversity into research on biosphere-atmosphere interactions. The proposal emerges from our studying the interactions of forests with atmospheric processes in the context of climate change using an individual-based forest volatile organic compounds model, UVAFME-VOC. This individual-based model can explicitly simulate VOC emissions based on an explicit modelling of forest dynamics by computing the growth, death, and regeneration of each individual tree of different species and their competition for light, moisture, and nutrient, from which system-level VOC emissions are simulated by explicitly computing and summing up each individual's emissions. We found that elevated O3 significantly altered the forest dynamics by favoring species that are O3-resistant, which, meanwhile, are producers of isoprene. Such compositional changes, on the one hand, resulted in unsuppressed forest productivity and carbon stock because of the compensation by O3-resistant species. On the other hand, with more isoprene produced arising from increased producers, a possible positive feedback loop between tropospheric O3 and forest thereby emerged. We also found that climate warming will not always stimulate isoprene emissions because warming simultaneously reduces isoprene emissions by causing a decline in the abundance of isoprene-emitting species. These results suggest that species diversity is of great significance and that individual-based modelling strategies should be applied in studying biosphere-atmosphere interactions.

Effective e-learning for health professionals and students--barriers and their solutions. A systematic review of the literature--findings from the HeXL project.

Science.gov (United States)

Childs, Sue; Blenkinsopp, Elizabeth; Hall, Amanda; Walton, Graham

2005-12-01

In 2003/4 the Information Management Research Institute, Northumbria University, conducted a research project to identify the barriers to e-learning for health professionals and students. The project also established possible ways to overcome these barriers. The North of England Workforce Development Confederation funded the project. The project comprised a systematic review of the literature on barriers to and solutions/critical success factors for e-learning in the health field. Fifty-seven references were suitable for analysis. This review was supplemented by a questionnaire survey of learners and an interview study of learning providers to ensure that data identified from the literature were grounded in reality. The main barriers are: requirement for change; costs; poorly designed packages; inadequate technology; lack of skills; need for a component of face-to-face teaching; time intensive nature of e-learning; computer anxiety. A range of solutions can solve these barriers. The main solutions are: standardization; strategies; funding; integration of e-learning into the curriculum; blended teaching; user friendly packages; access to technology; skills training; support; employers paying e-learning costs; dedicated work time for e-learning. The authors argue that librarians can play an important role in e-learning: providing support and support materials; teaching information skills; managing and providing access to online information resources; producing their own e-learning packages; assisting in the development of other packages.

A 12-bit spectroscopy analog-to-digital converter type SAA (Successive Approximation type with channel width Averaging) intended for multichannel pulse height analyzer SWAN-1 based on IBM PC/XT/AT

International Nuclear Information System (INIS)

Borsuk, S.; Kulka, Z.

1989-12-01

A 12-bit spectroscopy analog-to-digital converter (ADC) type SAA (Successive Approximation type with channel width Averaging) intended for multichannel pulse height analyzer SWAN-1 based on IBM PC/XT/AT has been described. Design principles, specifications and measurements of a fundamental SAA-2 converter version are reported. Finally, two next versions of the converter with introduced modifications are discussed. 6 refs., 7 figs. (author)

RL5SORT/RL5PLOT. A graphite package for the JRC-Ispra IBM version of RELAP5/MOD1

International Nuclear Information System (INIS)

Kolar, W.; Brewka, W.

1984-01-01

The present report describes the programs RL5SORT and RL5PLOT, their implementation and ''how to use''. Both programs base on the IBM version of RELAP5 as developed at JRC-ISPRA. RL5SORT creates from the output file (restart plot file) of a RELAP5 calculation data files, which serve as input data base for the program RL5PLOT. RL5PLOT retrieves the previous stored data records (minor edit quantities of RELAP5), allows arithmetic operations with the retrieved data and enables a print or graphic output on the terminal screen of a TEKTRONIX graphic terminal. A set of commands, incorporated in the program RL5PLOT, facilitates the user's work. Program RL5SORT has been developed as a batch program, while RL5PLOT has been conceived for interactive working mode

Advanced neutron source project information management. A model for the future

International Nuclear Information System (INIS)

King-Jones, K.; Cleaves, J.

1995-01-01

The Advanced Neutron Source (ANS) is a proposed new research facility that will provide steady-state beams of neutrons for experiments by more than 1000 researchers per year in the fields of materials science and engineering, biology, chemistry, materials analysis, and nuclear science. The facility will also include irradiation capabilities to produce radioisotopes for medical applications, research, industry, and materials testing. This paper discusses the architecture and data flow used by the project, some quantitative examinations of potential cost savings and return on investment and software applications used to generate and manage data across IBM-compatible personal computers, Macintosh, and Unix-based workstations. Personnel management aspects addressed include providing paper copy to users only when needed for adequate technical review, using graded approaches to providing support for numerous user-needed software applications, and implementing a phased approach to compliance with computer-aided acquisition and logistic support (CALS) standards that allows sufficient user flexibility for performing technical tasks while providing needed data sharing and integration

Advanced Neutron Source project information management: A model for the future

International Nuclear Information System (INIS)

King-Jones, K.; Cleaves, J.

1995-01-01

The Advanced Neutron Source (ANS) is a proposed new research facility that will provide steady-state beams of neutrons for experiments by more than 1,000 researchers per year in the fields of materials science and engineering, biology, chemistry, materials analysis, and nuclear science. The facility will also include irradiation capabilities to produce radioisotopes for medical applications, research, industry, and materials testing. This paper discusses the architecture and data flow used by the project, some quantitative examinations of potential cost savings and return on investment, and software applications used to generate and manage data across IBM-compatible personal computers, Macintosh, and Unix-based workstations. Personnel management aspects addressed include providing paper copy to users only when needed for adequate technical review, using graded approaches to providing support for numerous user-needed software applications, and implementing a phased approach to compliance with computer-aided acquisition and logistic support (CALS) standards that allows sufficient user flexibility for performing technical tasks while providing needed data sharing and integration

Towards the petaflop for Lattice QCD simulations the PetaQCD project

International Nuclear Information System (INIS)

D'Auriac, Jean-Christian Angles; Carbonell, Jaume; Barthou, Denis

2010-01-01

The study and design of a very ambitious petaflop cluster exclusively dedicated to Lattice QCD simulations started in early '08 among a consortium of 7 laboratories (IN2P3, CNRS, INRIA, CEA) and 2 SMEs. This consortium received a grant from the French ANR agency in July '08, and the PetaQCD project kickoff took place in January '09. Building upon several years of fruitful collaborative studies in this area, the aim of this project is to demonstrate that the simulation of a 256 x 128 3 lattice can be achieved through the HMC/ETMC software, using a machine with efficient speed/cost/reliability/power consumption ratios. It is expected that this machine can be built out of a rather limited number of processors (e.g. between 1000 and 4000), although capable of a sustained petaflop CPU performance. The proof-of-concept should be a mock-up cluster built as much as possible with off-the-shelf components, and 2 particularly attractive axis will be mainly investigated, in addition to fast all-purpose multi-core processors: the use of the new brand of IBM-Cell processors (with on-chip accelerators) and the very recent Nvidia GP-GPUs (off-chip co-processors). This cluster will obviously be massively parallel, and heterogeneous. Communication issues between processors, implied by the Physics of the simulation and the lattice partitioning, will certainly be a major key to the project.

IODP Expedition 351 Lithostratigraphy: Volcaniclastic Record of Izu-Bonin-Mariana (IBM) Arc Initiation

Science.gov (United States)

Barth, A. P.; Brandl, P. A.; Li, H.; Hickey-Vargas, R.; Jiang, F.; Kanayama, K.; Kusano, Y.; Marsaglia, K. M.; McCarthy, A.; Meffre, S.; Savov, I. P.; Tepley, F. J., III; Yogodzinski, G. M.

2014-12-01

The destruction of lithospheric plates by subduction is a fundamentally important process leading to arc magmatism and the creation of continental crust, yet subduction initiation and early magmatic arc evolution remain poorly understood. For many arc systems, onset of arc volcanism and early evolution are obscured by metamorphism or the record is deeply buried; however, initial products of arc systems may be preserved in forearc and backarc sedimentary records. IODP Expedition 351 recovered this history from the dispersed ash and pyroclast record in the proximal rear-arc of the northern IBM system west of the Kyushu-Palau Ridge. Drilling at Site U1438 in the Amami Sankaku Basin recovered a thick volcaniclastic record of subduction initiation and the early evolution of the Izu-Bonin Arc. A 160-m thick section of Neogene sediment overlies 1.3 kilometers of Paleogene volcaniclastic rocks with andesitic average composition; this volcaniclastic section was deposited on mafic volcanic basement rocks. The thin upper sediment layer is primarily terrigenous, biogenic and volcaniclastic mud and ooze with interspersed ash layers. The underlying Eocene to Oligocene volcaniclastic rocks are 33% tuffaceous mudstone, 61% tuffaceous sandstone, and 6% conglomerate with volcanic and rare sedimentary clasts commonly up to pebble and rarely to cobble size. The clastic section is characterized by repetitive conglomerate and sandstone-dominated intervals with intervening mudstone-dominated intervals, reflecting waxing and waning of coarse arc-derived sediment inputs through time. Volcanic lithic clasts in sandstones and conglomerates range from basalt to rhyolite in composition and include well-preserved pumice, reflecting a lithologically diverse and compositionally variable arc volcanic source.

40 CFR 262.103 - What is the scope of the laboratory environmental management standard?

Science.gov (United States)

2010-07-01

... environmental management standard? 262.103 Section 262.103 Protection of Environment ENVIRONMENTAL PROTECTION... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.103 What is the scope of the laboratory environmental management standard? The Laboratory Environmental Management Standard...

40 CFR 265.1080 - Applicability.

Science.gov (United States)

2010-07-01

... requirements of § 265.1090(c). (f) This section applies only to the facility commonly referred to as the OSi... Water 8 model or other model agreed to by the Sistersville Plant, EPA and WVDEP) under Project XL with...

ANALISIS ELEMEN-ELEMEN BRAND EQUITY PADA PRODUK KARTU SELULER PRABAYAR SIMPATI, IM3, DAN XL DI KALANGAN MAHASISWA S1 UNIVERSITAS DIPONEGORO

Directory of Open Access Journals (Sweden)

Arfan Bakhtiar

2015-11-01

Full Text Available Era globalisasi menjanjikan suatu peluang dan tantangan bisnis baru bagi perusahaan yang beroperasi di Indonesia. Salah satu industri yang sangat ketat persaingannya adalah industri telekomunikasi. Di Indonesia saat ini terdapat tiga perusahaan GSM yang menguasai pasar yang bergerak dalam industri ini, perusahaan itu adalah IM3 yang dikeluarkan oleh PT. Indosat TBK, XL yang dikeluarkan PT. Excelcomindo Pratama dan Simpati yang dikeluarkan oleh PT. Telekomunikasi Seluler. Penelitian ini bertujuan untuk meneliti elemen-elemen ekuitas merek dari ketiga merek kartu telepon tersebut. Manfaat yang diperoleh dari penelitian ini adalah memberikan informasi kepada para pembaca mengenai produk kartu telepon apa yang paling diingat konsumen asosiasi-asosiasi apa saja yang melekat pada kartu-kartu telepon tersebut, produk kartu telepon apa yang memiliki tingkat loyalitas paling tinggi, serta bagaimana persepsi kualitas konsumen terhadap kartu-kartu tersebut. Pengujian hipotesis dalam penelitian ini akan menggunakan Uji Cohran. Dari hasil penelitian yang dilakukan pada tiap elemen-elemennya, didapat bahwa produk kartu Simpati adalah produk yang memiliki tingkat brand awareness paling tinggi, asosiasi produk yang paling banyak adalah Simpati dengan 7 asosiasi, tingkat loyalitas konsumen pengguna kartu telepon yang paling tinggi adalah kartu Simpati, serta kartu telepon yang memiliki brand perceived quality yang diukur berdasarkan performance dan importancenya adalah kartu Simpati.   Kata kunci: brand association; brand awareness; brand equity;brand loyalty; perceived quality Abstract The globalization era provides new business opportunities and challenges for industries operating in Indonesia. One of the industries that has tight competition is telecommunications industry. In Indonesia, there are currently three GSM industries that dominate the market that engaged in the industry. They are IM3, owned by Indosat TBK Ltd., XL, owned by Excelcomindo Pratama Ltd

Astronomy Legacy Project - Pisgah Astronomical Research Institute

Science.gov (United States)

Barker, Thurburn; Castelaz, Michael W.; Rottler, Lee; Cline, J. Donald

2016-01-01

Pisgah Astronomical Research Institute (PARI) is a not-for-profit public foundation in North Carolina dedicated to providing hands-on educational and research opportunities for a broad cross-section of users in science, technology, engineering and math (STEM) disciplines. In November 2007 a Workshop on a National Plan for Preserving Astronomical Photographic Data (2009ASPC,410,33O, Osborn, W. & Robbins, L) was held at PARI. The result was the establishment of the Astronomical Photographic Data Archive (APDA) at PARI. In late 2013 PARI began ALP (Astronomy Legacy Project). ALP's purpose is to digitize an extensive set of twentieth century photographic astronomical data housed in APDA. Because of the wide range of types of plates, plate dimensions and emulsions found among the 40+ collections, plate digitization will require a versatile set of scanners and digitizing instruments. Internet crowdfunding was used to assist in the purchase of additional digitization equipment that were described at AstroPlate2014 Plate Preservation Workshop (www.astroplate.cz) held in Prague, CZ, March, 2014. Equipment purchased included an Epson Expression 11000XL scanner and two Nikon D800E cameras. These digital instruments will compliment a STScI GAMMA scanner now located in APDA. GAMMA will be adapted to use an electroluminescence light source and a digital camera with a telecentric lens to achieve high-speed high-resolution scanning. The 1μm precision XY stage of GAMMA will allow very precise positioning of the plate stage. Multiple overlapping CCD images of small sections of each plate, tiles, will be combined using a photo-mosaic process similar to one used in Harvard's DASCH project. Implementation of a software pipeline for the creation of a SQL database containing plate images and metadata will be based upon APPLAUSE as described by Tuvikene at AstroPlate2014 (www.astroplate.cz/programs/).

What on earth is a mainframe ? an introduction to IBM zSeries mainframes and z/OS operating systems for total beginners

CERN Document Server

Stephens, David

2008-01-01

Looking for a "Mainframes for Beginners" book? Need to learn about z/OS fast? Then this is the book you need. This is the perfect introduction to IBM System z Mainframes and z/OS. Avoiding technical jargon, it gives you the basic facts in clear, light-hearted, entertaining English. You'll quickly learn what Mainframes are, what they do, what runs on them, and terms and terminology you need to speak Mainframe-ese. But it's not all technical. There's also invaluable information about the people that work on Mainframes, Mainframe management issues, new Mainframe trends, and other facts that don't seem to be written down anywhere else. What On Earth is a Mainframe is the closest you'll get to a "Mainframes for Dummies" book. Programmers, managers, recruitment consultants, and industry commentators will all find this book their new best friend when trying to understand the Mainframe world.

B(IS4;0GS+→4γ+) systematics in rare-earth nuclei: SU sdg (3) description

International Nuclear Information System (INIS)

Devi, Y.D.; Kota, V.K.B.

1993-01-01

The observed variation of B(IS4; 0 GS + →4 γ + ) with mass number A, that gives information about hexadecupole component in γ-vibration, in rare-earth nuclei is studied in the SU sdg (3) limit of sdg interacting boson model empoloying IBM-2 to IBM-1 projected hexadecupole transition operator with effective charges determined using a multi-j shell mapping procedure. The SU sdg (3) limit provides a reasonably good description of the data. (orig.)

Statistical Analysis of the Skaion Network Security Dataset

Science.gov (United States)

2012-09-01

DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False, _ Semicolon:=False, Comma:=False, Space...Selection.TextToColumns Destination:=Range(“E1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False...True Columns(“F:F”).Select Selection.TextToColumns Destination:=Range(“F1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote

The implementation of the CDC version of RELAP5/MOD1/019 on an IBM compatible computer system (AMDAHL 470/V8)

International Nuclear Information System (INIS)

Kolar, W.; Brewka, W.

1984-01-01

RELAP5/MOD1 is an advanced one-dimensional best estimate system code, which is used for safety analysis studies of nuclear pressurized water reactor systems and related integral and separate effect test facilities. The program predicts the system response for large break, small break LOCA and special transients. To a large extent RELAP5/MOD1 is written in Fortran, only a small part of the program is coded in CDC assembler. RELAP5/MOD1 was developed on the CDC CYBER 176 at INEL*. The code development team made use of CDC system programs like the CDC UPDATE facility and incorporated in the program special purpose software packages. The report describes the problems which have been encountered when implementing the CDC version of RELAP5/MOD1 on an IBM compatible computer systems (AMDAHL 470/V8)

Comparison of three methods of tonometry in normal subjects: Goldmann applanation tonometer, non-contact airpuff tonometer, and Tono-Pen XL.

Science.gov (United States)

Yilmaz, Ihsan; Altan, Cigdem; Aygit, Ebru Demet; Alagoz, Cengiz; Baz, Okkes; Ahmet, Sibel; Urvasizoglu, Semih; Yasa, Dilek; Demirok, Ahmet

2014-01-01

WE AIMED TO COMPARE INTRAOCULAR PRESSURE (IOP) MEASUREMENTS VIA THREE DIFFERENT TONOMETERS: the Goldmann applanation tonometer (GAT), the Tono-Pen(®) XL (TPXL), and a non-contact airpuff tonometer (NCT). This was a cross-sectional study of 200 eyes from 200 patients. Right eyes of all patients were included in this study. IOP was measured via GAT, NCT, and TPXL by three physicians. Each physician used one of the tonometers. Measurements via the three devices were compared. The mean IOP was 15.5±2.2 mmHg (range 10-22) with the GAT, 16.1±3.0 (range 9-25) with the TPXL, and 16.1±2.8 (range 10-26) with the NCT. Bland-Altman analysis showed that the mean difference between measurements from the NCT and the GAT was 0.6±2.3 mmHg. The mean difference between the TPXL and GAT measurements was 0.7±2.5 mmHg. The mean difference between the NCT and TPXL measurements was -0.02±3.0 mmHg. There was no significant difference between the groups according to a one-way analysis of variance (ANOVA) test. P-values were 0.998 for NCT-TPXL, 0.067 for NCT-GAT, and 0.059 for TPXL-GAT. The NCT and TPXL provide IOP measurements comparable to those of the gold standard GAT in normotensive eyes.

Optimizing The Performance of Streaming Numerical Kernels On The IBM Blue Gene/P PowerPC 450

KAUST Repository

Malas, Tareq

2011-07-01

Several emerging petascale architectures use energy-efficient processors with vectorized computational units and in-order thread processing. On these architectures the sustained performance of streaming numerical kernels, ubiquitous in the solution of partial differential equations, represents a formidable challenge despite the regularity of memory access. Sophisticated optimization techniques beyond the capabilities of modern compilers are required to fully utilize the Central Processing Unit (CPU). The aim of the work presented here is to improve the performance of streaming numerical kernels on high performance architectures by developing efficient algorithms to utilize the vectorized floating point units. The importance of the development time demands the creation of tools to enable simple yet direct development in assembly to utilize the power-efficient cores featuring in-order execution and multiple-issue units. We implement several stencil kernels for a variety of cached memory scenarios using our Python instruction simulation and generation tool. Our technique simplifies the development of efficient assembly code for the IBM Blue Gene/P supercomputer\\'s PowerPC 450. This enables us to perform high-level design, construction, verification, and simulation on a subset of the CPU\\'s instruction set. Our framework has the capability to implement streaming numerical kernels on current and future high performance architectures. Finally, we present several automatically generated implementations, including a 27-point stencil achieving a 1.7x speedup over the best previously published results.

Determination of the zero in the Two theta angle and the wavelength in the neutron diffractometer for the Cyber computer of the ININ and for the IBM compatible microcomputers; Determinacion del cero en el angulo Dos teta y la longitud de onda en el difractometro de neutrones para la computadora Cyber del ININ y para microcomputadoras compatibles con IBM

Energy Technology Data Exchange (ETDEWEB)

Macias B, L R

1991-05-15

The objective of this work consists on determining the calibration in the angular parameters and the neutron wavelength used in the neutron diffractometer of the TRIGA Mark III reactor, through some readings in that a well-known sample is used by means of a Fortran computer program that is used in the CYBER computer of the ININ in Mexico, and/or in micro computers compatible with IBM. The program was also designed to determine the zero of the 2 {theta} angle of the goniometer of the diffractometer. The generated data were proven by means of well-known data of the Powder Diffraction File of the Joint Committee on Powder Diffraction Standards (JCPDS). (Author)

A Physicist Role in Innovation within IBM Research

Science.gov (United States)

Gallagher, William

2014-03-01

The broad and deep insight a physicist brings to the goings on in a large technology company lead to many varied and exciting opportunities. Examples in my own career include contributions to important understanding of new breakthroughs (understanding the basic anisotropy of high temperature superconductivity), bringing vital physics understanding to ambitious engineering projects (basic switching and noise margins in digital Josephson junction technology), and initiating and growing large applied projects based on fundamental physics breakthroughs (magnetoresistive random access memory - MRAM). Success at such undertakings within a large enterprise involves a number of factors. Always seeking out the best expert advice and the best collaborators in unfamiliar technical areas as new ideas develop is enormously helpful and not at all difficult within a large innovative organization. While being imaginative and optimistic, one must also remain brutally honest about the potential value of new endeavors, the hurdles ahead, and the likelihood of success. Always, however, there is no substitute hard work. I can attest that the results of efforts along these directions within a technology company can be very exciting and satisfying, and the process along the way a whole lot of fun.

Registered report: Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

OpenAIRE

sprotocols

2015-01-01

Authors: David Blum, Samuel LaBarge, The Reproducibility Project: Cancer Biology†* ### Abstract The [Reproducibility Project: Cancer Biology](https://osf.io/e81xl/wiki/home/) seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered Report describes the proposed replication plan of key experiments from “Tumour micro-environment elicits innate res...

Registered report: Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors2

OpenAIRE

sprotocols

2015-01-01

Authors: Edward Greenfield, Erin Griner, The Reproducibility Project: Cancer Biology† ### Abstract The [Reproducibility Project: Cancer Biology](https://osf.io/e81xl/wiki/home/) seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered Report describes the proposed replication plan of key experiments from “Widespread potential for growth-factor-d...

Technology for national asset storage systems

Science.gov (United States)

Coyne, Robert A.; Hulen, Harry; Watson, Richard

1993-01-01

An industry-led collaborative project, called the National Storage Laboratory, was organized to investigate technology for storage systems that will be the future repositories for our national information assets. Industry participants are IBM Federal Systems Company, Ampex Recording Systems Corporation, General Atomics DISCOS Division, IBM ADSTAR, Maximum Strategy Corporation, Network Systems Corporation, and Zitel Corporation. Industry members of the collaborative project are funding their own participation. Lawrence Livermore National Laboratory through its National Energy Research Supercomputer Center (NERSC) will participate in the project as the operational site and the provider of applications. The expected result is an evaluation of a high performance storage architecture assembled from commercially available hardware and software, with some software enhancements to meet the project's goals. It is anticipated that the integrated testbed system will represent a significant advance in the technology for distributed storage systems capable of handling gigabyte class files at gigabit-per-second data rates. The National Storage Laboratory was officially launched on 27 May 1992.

Modulation-free bismuth-lead cuprate superconductors: BiPbSr1+xL1-xCuO6 and BiPbSr2Y1-xCaxCu2O8

International Nuclear Information System (INIS)

Manivannan, V.; Gopalakrishnan, J.; Rao, C.N.R.

1991-01-01

Modulation-free BiPbSrLCuO 6 (L=La, Pr, Nd) and BiPbSr 2 YCu 2 O 8 , which are isotypic with the n=1 and 2 members of the Bi 2 Sr 2 Ca n-1 Cu n O 2n+4 family, have been prepared and characterized. These parent compounds are nonsuperconducting, but when doped with holes by substitution chemistry give modulation-free superconducting cuprates of the general formulas BiPbSr 1+xL1-x CuO 6 and BiPbSr 2 Y 1-x Ca x Cu 2 O 8 , exhibiting maximum T c 's of 24 and 85 K, respectively. Significantly, the hole concentration at the maximum T c is 0.12 in the cuprate family with a single Cu-O layer and 0.22 in that with two Cu-O layers

Management Tools

Science.gov (United States)

1987-01-01

Manugistics, Inc. (formerly AVYX, Inc.) has introduced a new programming language for IBM and IBM compatible computers called TREES-pls. It is a resource management tool originating from the space shuttle, that can be used in such applications as scheduling, resource allocation project control, information management, and artificial intelligence. Manugistics, Inc. was looking for a flexible tool that can be applied to many problems with minimal adaptation. Among the non-government markets are aerospace, other manufacturing, transportation, health care, food and beverage and professional services.

Evaluation of tile layer productivity in construction project

Science.gov (United States)

Aziz, Hamidi Abdul; Hassan, Siti Hafizan; Rosly, Noorsyalili; Ul-Saufie, Ahmad Zia

2017-10-01

Construction is a key sector of the national economy for countries all over the world. Until today, construction industries are still facing lots of problems concerning the low productivity, poor safety and insufficient quality. Labour productivity is one of the factors that will give impact to the quality of projects. This study is focusing on evaluating the tile layer productivity in the area of Seberang Perai, Penang. The objective of this study is to determine the relationship of age and experience of tile layers with their productivity and to evaluate the effect of nationality to tile layers productivity. Interview and site observation of tile layers has been conducted to obtain the data of age, experience and nationality of tile layers. Site observation is made to obtain the number of tiles installed for every tile layer for the duration of 1 hour, and the data were analysed by using Statistical Package for Social Science (IBM SPSS Statistic 23) software. As a result, there is a moderate linear relationship between age and experience of tile layers with their productivity. The age of 30 and the experience of 4 years give the highest productivity. It also can be concluded that the tile layers from Indonesia tend to have higher productivity compared to tile layers from Myanmar.

Band mixing effects in mean field theories

International Nuclear Information System (INIS)

Kuyucak, S.; Morrison, I.

1989-01-01

The 1/N expansion method, which is an angular momentum projected mean field theory, is used to investigate the nature of electromagnetic transitions in the interacting boson model (IBM). Conversely, comparison with the exact IBM results sheds light on the range of validity of the mean field theory. It is shown that the projected mean field results for the E2 transitions among the ground, β and γ bands are incomplete for the spin dependent terms and it is essential to include band mixing effect for a correct (Mikhailov) analysis of E2 data. The algebraic expressions derived are general and will be useful in the analysis of experimental data in terms of both the sd and sdg boson models. 17 refs., 7 figs., 8 tabs

Project Report on DOE Young Investigator Grant (Contract No. DE-FG02-02ER25525) Dynamic Scheduling and Fusion of Irregular Computation (August 15, 2002 to August 14, 2005)

Energy Technology Data Exchange (ETDEWEB)

Ding, Chen

2005-08-16

may use an enormous number of data elements. To optimize the layout across multiple arrays, we have developed a formal model called reference afï¬ nity. We collaborated with the IBM production compiler group and designed an efï¬ cient compiler analysis that performs as well as data or code proï¬ ling does. Based on these results, the IBM group has ï¬ led a patent and is including this technique in their product compiler. A major part of the project is the development of software tools. We have developed web-based visu- alization for program locality. In addition, we have implemented a prototype of array regrouping in the IBM compiler. The full implementation is expected to come out of IBM in the near future and to beneï¬ t scientiï¬ c applications running on IBM supercomputers. We have also developed a test environment for studying the limit of computation fusion. Finally, our work has directly influenced the design of the Intel Itanium compiler. The project has strengthened the research relation between the PI's group and groups in DoE labs. The PI was an invited speaker at the Center for Applied Scientiï¬ c Computing Seminar Series at the early stage of the project. The question that the most audience was curious about was the limit of computation fusion, which has been studied in depth in this research. In addition, the seminar directly helped a group at Lawrence Livermore to achieve four times speedup on an important DoE code. The PI helped to organize a number of high-performance computing forums, including the founding of a workshop on memory system performance (MSP). In the past two years, one fourth of the papers in the workshop came from researchers in Lawrence Livermore, Argonne, Las Alamos, and Lawrence Berkeley national laboratories. The PI lectured frequently on DoE funded research. In a broader context, high performance computing is central to America's scientific and economic stature in the world, and addresses many of the most

Theoretical research in nuclear collective motion. Progress report

International Nuclear Information System (INIS)

1984-01-01

Progress is summarized on the following research projects: generalized density matrix method, large amplitude collective motion, boson mappings for the Interacting Boson Model, and semi-classical method for testing IBM hypothesis

The Lipopolysaccharide Lipid A Long-Chain Fatty Acid Is Important for Rhizobium leguminosarum Growth and Stress Adaptation in Free-Living and Nodule Environments.

Science.gov (United States)

Bourassa, Dianna V; Kannenberg, Elmar L; Sherrier, D Janine; Buhr, R Jeffrey; Carlson, Russell W

2017-02-01

Rhizobium bacteria live in soil and plant environments, are capable of inducing symbiotic nodules on legumes, invade these nodules, and develop into bacteroids that fix atmospheric nitrogen into ammonia. Rhizobial lipopolysaccharide (LPS) is anchored in the bacterial outer membrane through a specialized lipid A containing a very long-chain fatty acid (VLCFA). VLCFA function for rhizobial growth in soil and plant environments is not well understood. Two genes, acpXL and lpxXL, encoding acyl carrier protein and acyltransferase, are among the six genes required for biosynthesis and transfer of VLCFA to lipid A. Rhizobium leguminosarum mutant strains acpXL, acpXL - /lpxXL - , and lpxXL - were examined for LPS structure, viability, and symbiosis. Mutations in acpXL and lpxXL abolished VLCFA attachment to lipid A. The acpXL mutant transferred a shorter acyl chain instead of VLCFA. Strains without lpxXL neither added VLCFA nor a shorter acyl chain. In all strains isolated from nodule bacteria, lipid A had longer acyl chains compared with laboratory-cultured bacteria, whereas mutant strains displayed altered membrane properties, modified cationic peptide sensitivity, and diminished levels of cyclic β-glucans. In pea nodules, mutant bacteroids were atypically formed and nitrogen fixation and senescence were affected. The role of VLCFA for rhizobial environmental fitness is discussed.

Contrasting the crospovidones functionality as excipients for direct compression

Directory of Open Access Journals (Sweden)

Daniel García Ramírez

2015-03-01

Full Text Available Specific values of technological properties of excipients allow the establishment of numerical parameters to define and compare their functionality. This study investigates the functionality of Polyplasdones XL and XL10. Parameters studied included tablet disintegration profiles, compactibility profiles and powder flow. The results allowed the establishment of quantitative surrogate functionalities of technological performance, such as absolute number, and as a value relative to the known microcrystalline cellulose type 102. Moreover, the establishment of an explicit functionality to improve the technological performance of two diluents and a model drug was investigated, as was setting up of these functionalities, as quantitative values, to determine the input variables of each material and its probable functionality in a drug product. Disintegration times of pure Polyplasdone XL and its admixtures were around half that of Polyplasdone XL10. The improvement in tablet compactibility was 25-50% greater for Polyplasdone XL10 than Polyplasdone XL. Crospovidones proportions of up to 10% have little effect on the flow properties of other powders, although pure Polyplasdone XL10 and its admixtures display compressibility indexes about 20% greater than Polyplasdone XL. The observed results are in line with a smaller particle size of Polyplasdone XL10 compared to Polyplasdone XL.

Still 331 days until year 2000

International Nuclear Information System (INIS)

Nonhoff, E.; Woegerbauer, S.

1999-01-01

Presentation deals with the project experience concerning Y2K issues at IBM. IBM is committed to help customers and has the following customer support approach: perform call center modelling, utilize service planning experience, review previous critical situation experience. General problems and mistakes are listed, strategy established and detailed analysis and planning are described together with remediation and test. Contingency planning work includes: evaluation of the current environment, examination of plausible alternative futures, preparation of contingency plans for critical processes, identification and monitoring of key signposts, action to shape more favourable future

Materials information for science and technology (MIST): Project overview: Phases I and II and general considerations

Energy Technology Data Exchange (ETDEWEB)

Grattidge, W.; Westbrook, J.; McCarthy, J.; Northrup, C. Jr.; Rumble, J. Jr.

1986-01-01

This report documents the initial phases of the Materials Information for Science and Technology (MIST) project jointly supported by the Department of Energy and the National Bureau of Standards. The purpose of MIST is to demonstrate the power and utility of computer access to materials property data. The initial goals include: to exercise the concept of a computer network of materials databases and to build a demonstration of such a system suitable for use as the core of operational systems in the future. Phases I and II are described in detail herein. In addition, a discussion is given of the expected usage of the system. The primary MIST prototype project is running on an IBM 3084 under STS at the Stanford University's Information Technology Services (ITS). Users can access the Stanford system via ARPANET, TELENET, and TYMNET, as well as via commercial telephone lines. For fastest response time and use of the full screen PRISM interface, direct connection using a 2400 baud modem with the MNP error-correcting protocol over standard telephone lines gives the best results - though slower speed connections and a line-oriented interface are also available. This report gives detailed plans regarding the properties to be enterend and the materials to be entered into the system.

76 FR 59578 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

Science.gov (United States)

2011-09-27

... Carrocerias Cimarron trailer........ 2006-2007 37 Chevrolet 400SS 1995 150 Chevrolet Astro Van 1997 298... Davidson (MC) FX, FL, XL Series....... 1998 253 Harley Davidson (MC) FX, FL, XL Series....... 1999 281 Harley Davidson (MC) FX, FL, XL Series....... 2000 321 Harley Davidson (MC) FX, FL, XL Series....... 2001...

January: IBM 7094 programme for the resolution of cell problems in planar, spherical and cylindrical geometry using the double P{sub n} approximation; Janvier: programme de resolution sur IBM 7094 des problemes de cellules en geometrie plane, spherique et cylindrique dans l'approximation double P{sub n}

Energy Technology Data Exchange (ETDEWEB)

Amouyal, A; Tariel, H [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1966-07-01

Code name: January 1{sup st} SCEA 011S. 2) Computer: IBM 7094; Programme system: Fortran II, 2{sup nd} version. 3) Nature of the problem: resolution of cell problems with one space variable (planar, spherical and cylindrical geometries) and with one energy group, with isotropic sources in the double P{sub n} approximation (DP 1 and DP 3 approximation in planar and spherical geometries, DP 1 and DP 2 in cylindrical geometry). 4) Method used: the differential equations with limiting conditions are transformed into differential system with initial conditions which are integrated by a separate-step method. 5) Restrictions: number of physical media < 100, number of geometrical regions < 100, number of points < 1000. 6) Physical approximations: limiting conditions for reflection, black body or grey body (restrictions for spherical and cylindrical geometries). The diffusion can include an isotropy term in cylindrical geometry, 2 terms in the other geometries. Taking into account of macroscopic data. 7) Duration: calculation time for a network of 100 points: planar and spherical geometry: double P 1 1 second, D P 3 = 4 seconds; cylindrical geometry: double P 1 2 seconds, D P 2 = 4 seconds. To these times should be added the 3 seconds required for the output. 8) State of the programme under production. (authors) [French] 1) Nom du Code: Janvier 1 SCEA 011S. 2) Calculateur: IBM 7094; Systeme de programmation: Fortran II version-2. 3) Nature du probleme: resolution des problemes de cellule a une variable d'espace (geometries plane, spherique et cylindrique) et un groupe d'energie, avec sources isotropes, dans l'approxirnation double P{sub n} (Approximations DP 1 et DP 3 en geometrie plane et spherique, approximations DP 1 et DP 2 en geometrie cylindrique). Methode employee: les equations differentielles avec conditions aux limites sont transformees en systemes differentiels avec conditions initiales que l'on integre par une methode a pas separes. 5) Restrictions: nombre de

Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

Directory of Open Access Journals (Sweden)

Hastie C James

2006-01-01

Full Text Available Abstract Background Pim-1, 2 and 3 are a group of enzymes related to the calcium calmodulin family of protein kinases. Over-expression of Pim-1 and Pim-2 in mice promotes the development of lymphomas, and up-regulation of Pim expression has been observed in several human cancers. Results Here we show that the pim kinases are constitutively active when expressed in HEK-293 cells and are able to phosphorylate the Bcl-2 family member Bad on three residues, Ser112, Ser136 and Ser155 in vitro and in cells. In vitro mapping showed that Pim-2 predominantly phosphorylated Ser112, while Pim-1 phosphorylated Ser112, but also Ser136 and Ser155 at a reduced rate compared to Ser112. Pim-3 was found to be the least specific for Ser112, and the most effective at phosphorylating Ser136 and Ser155. Pim-3 was also able to phosphorylate other sites in Bad in vitro, including Ser170, another potential in vivo site. Mutation of Ser136 to alanine prevented the phosphorylation of Ser112 and Ser155 by Pim kinases in HEK-293 cells, suggesting that this site must be phosphorylated first in order to make the other sites accessible. Pim phosphorylation of Bad was also found to promote the 14-3-3 binding of Bad and block its association with Bcl-XL. Conclusion All three Pim kinase family members predominantly phosphorylate Bad on Ser112 and in addition are capable of phosphorylating Bad on multiple sites associated with the inhibition of the pro-apoptotic function of Bad in HEK-293 cells. This would be consistent with the proposed function of Pim kinases in promoting cell proliferation and preventing cell death.

Project A+, Elementary Technology Demonstration Schools, 1991-92: The Second Year.

Science.gov (United States)

Nichols, Todd; Frazer, Linda

The Elementary Technology Demonstration Schools program, where four elementary schools were equipped with computer hardware and software, was made possible by grants from IBM and Apple, Inc. The goals of the program were, in 3 years, to reduce by 50% the number of students not in their age appropriate grade level and those students not achieving…

SIOB: a FORTRAN code for least-squares shape fitting several neutron transmission measurements using the Breit--Wigner multilevel formula. [For IBM-360/91

Energy Technology Data Exchange (ETDEWEB)

de Saussure, G.; Olsen, D. K.; Perez, R. B.

1978-05-01

The FORTRAN-IV code SIOB was developed to least-square fit the shape of neutron transmission curves. Any number of measurements on a common energy scale for different sample thicknesses can be simultaneously fitted. The computed transmission curves can be broadened with either a Gaussian or a rectangular resolution function or both, with the resolution width a function of energy. The total cross section is expressed as a sum of single-level or multilevel Breit--Wigner terms and Doppler broadened by using the fast interpolation routine QUICKW. The number of data points, resonance levels, and variables which can be handled simultaneously is only limited by the overall dimensions of two arrays in the program and by the stability of the matrix inversion. In a test problem seven transmissions each with 3750 data points were simultaneously fitted with 74 resonances and 110 variable parameters. The problem took 47 min of CPU time on an IBM-360/91, for 3 iterations. 3 figures, 2 tables.

Data Management Plan: HarassMap

OpenAIRE

Reem Wael

2017-01-01

HarassMap is an Egyptian organisation that works to create an environment where sexual harassment is not tolerated, and where individuals and institutions take action against it. For the purpose of this project, the project team cleaned up, organised, and made openly available for the public to access and use through a web portal, three main types of data: Crowdsourced reports of sexual harassment incidents (reports on HarassMap’s online reporting and mapping system) - CSV and XL...

Determination of the zero in the Two theta angle and the wavelength in the neutron diffractometer for the Cyber computer of the ININ and for the IBM compatible microcomputers

International Nuclear Information System (INIS)

Macias B, L.R.

1991-05-01

The objective of this work consists on determining the calibration in the angular parameters and the neutron wavelength used in the neutron diffractometer of the TRIGA Mark III reactor, through some readings in that a well-known sample is used by means of a Fortran computer program that is used in the CYBER computer of the ININ in Mexico, and/or in micro computers compatible with IBM. The program was also designed to determine the zero of the 2 θ angle of the goniometer of the diffractometer. The generated data were proven by means of well-known data of the Powder Diffraction File of the Joint Committee on Powder Diffraction Standards (JCPDS). (Author)

The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells.

Science.gov (United States)

Thijssen, R; Ter Burg, J; van Bochove, G G W; de Rooij, M F M; Kuil, A; Jansen, M H; Kuijpers, T W; Baars, J W; Virone-Oddos, A; Spaargaren, M; Egile, C; van Oers, M H J; Eldering, E; Kersten, M J; Kater, A P

2016-02-01

The phosphoinositide 3-kinases (PI3Ks) are critical components of the B-cell receptor (BCR) pathway and have an important role in the pathobiology of chronic lymphocytic leukemia (CLL). Inhibitors of PI3Kδ block BCR-mediated cross-talk between CLL cells and the lymph node microenvironment and provide significant clinical benefit to CLL patients. However, the PI3Kδ inhibitors applied thus far have limited direct impact on leukemia cell survival and thus are unlikely to eradicate the disease. The use of inhibitors of multiple isoforms of PI3K might lead to deeper remissions. Here we demonstrate that the pan-PI3K/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) was more pro-apoptotic to CLL cells--irrespective of their ATM/p53 status--than PI3Kα or PI3Kδ isoform selective inhibitors. Furthermore, SAR245409 blocked CLL survival, adhesion and proliferation. Moreover, SAR245409 was a more potent inhibitor of T-cell-mediated production of cytokines, which support CLL survival. Taken together, our in vitro data provide a rationale for the evaluation of a pan-PI3K inhibitor in CLL patients.

The proton-neutron symmetry in collective excitation of medium-heavy nuclei

International Nuclear Information System (INIS)

Frank, W.

1990-01-01

In the present thesis explicit formulas were given, which allow the projection of arbitrary one- and two-particle IBM-2 operators to IBM-1 operators, i.e. the results are not confined to the usual sd or sdg space, but are valid for arbitrary spatial multipolarities of the bosons. By this projection of the Hamiltonian and the transition operators could be derived. Explicitely the sd and sdg Hamiltonian were treated. By the projection formalism the dependence of the M1 and E2 matrix elements on the boson numbers N π and N ν could be determined if their sum is constant. The nuclei with constant total boson number form a F-spin multiplet. The results were applied to the A ≅ 50 region. In order to test the correctness of the projection formulae comprehensive, numerical tests for the sd case were performed. The projection method is valid for practical application, as far as the F spin is a good quantum number. A large number of experimental data shows that the F spin is approximatively conserved. As example served the analysis of 58 Fe. (orig./HSI) [de

IRiS: construction of ARG networks at genomic scales.

Science.gov (United States)

Javed, Asif; Pybus, Marc; Melé, Marta; Utro, Filippo; Bertranpetit, Jaume; Calafell, Francesc; Parida, Laxmi

2011-09-01

Given a set of extant haplotypes IRiS first detects high confidence recombination events in their shared genealogy. Next using the local sequence topology defined by each detected event, it integrates these recombinations into an ancestral recombination graph. While the current system has been calibrated for human population data, it is easily extendible to other species as well. IRiS (Identification of Recombinations in Sequences) binary files are available for non-commercial use in both Linux and Microsoft Windows, 32 and 64 bit environments from https://researcher.ibm.com/researcher/view_project.php?id = 2303 parida@us.ibm.com.

Development of neutron activation analysis software

International Nuclear Information System (INIS)

Wang Liyu

1987-10-01

The software for quantitative neutron activation analysis was developed to run under the MS/DOS operating system. The programmes of the IBM/SPAN include: spectra file transfer from and to a Canberra Series 35 multichannel analyzer, spectrum evaluation routines, calibration subprogrammes, and quantitative analysis. The programmes for spectrum analysis include fitting routine for separation of multiple lines by reproducing the peak shape with a combination of Gaussian and exponential terms. The programmes were tested on an IBM/AT-compatible computer. The programmes and the sources are available costfree for the IAEA projects of Technical Cooperation. 7 refs, 3 figs

Eikonal Scattering in the sdg Interacting Boson Model:. Analytical Results in the SUsdg(3) Limit and Their Generalizations

Science.gov (United States)

Kota, V. K. B.

General expression for the representation matrix elements in the SUsdg(3) limit of the sdg interacting boson model (sdgIBM) is derived that determine the scattering amplitude in the eikonal approximation for medium energy proton-nucleus scattering when the target nucleus is deformed and it is described by the SUsdg(3) limit. The SUsdg(3) result is generalized to two important situations: (i) when the target nucleus ground band states are described as states arising out of angular momentum projection from a general single Kπ = 0+ intrinsic state in sdg space; (ii) for rotational bands built on one-phonon excitations in sdgIBM.

Using Networks For Changing Innovation Strategy: The Case of IBM

NARCIS (Netherlands)

K. Dittrich (Koen); G.M. Duysters (Geert); A-P. de Man (Ard-Pieter)

2004-01-01

textabstractLarge-scale strategic change projects in companies may be supported by using alliance networks. This paper shows that IBM’s change from an exploitation strategy towards an exploration strategy required a radically different network strategy as well. By entering into more non-equity

A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XL.

Science.gov (United States)

Hwang, Jung Jin; Kim, Yong Sook; Kim, Taelim; Kim, Mi Joung; Jeong, In Gab; Lee, Je-Hwan; Choi, Jene; Jang, Sejin; Ro, Seonggu; Kim, Choung-Soo

2012-08-01

We synthesized a novel hydroxamate-based pan-histone deacetylase inhibitor (HDACI), CG200745 {(E)-2-(Naphthalen-1-yloxymethyl)-oct-2-enedioic acid 1-[(3-dimethylamino-propyl)-amide] 8-hydroxyamide]}. Like other inhibitors, for example vorinostat and belinostat, CG200745 has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Firstly, we analyzed its inhibitory activity against histone deacetylase (HDAC) in hormone-dependent LNCaP cells and hormone-independent DU145 and PC3 cells. CG200745 inhibited deacetylation of histone H3 and tubulin as much as vorinostat and belinostat did. CG200745 also inhibited growth of prostate cancer cells, increased sub-G1 population, and activated caspase-9, -3 and -8 in LNCaP, DU145 and PC3 cells. These results indicate that CG200745 induces apoptosis. Next, we examined the effect of CG200745 on cell death induced by docetaxel in DU145 cells in vitro and in vivo. Compared to mono-treatment with each drug, pre-treatment of DU145 cells with docetaxel followed by CG200745 showed synergistic cytotoxicity, and increased the apoptotic sub-G1 population, caspase activation, and tubulin acetylation. Moreover, the combination treatment decreased Mcl-1 and Bcl-(XL). Docetaxel and CG200745 combination reduced tumor size in the DU145 xenograft model. These preclinical results show that combination treatment with docetaxel and new HDACI, CG200745, potentiated anti-tumor effect in hormone-refractory prostate cancer (HRPC) cells via activation of apoptosis.

Caribou, individual-based modeling and mega-industry in central West Greenland

DEFF Research Database (Denmark)

Raundrup, Katrine; Nymand, Josephine; Nabe-Nielsen, Jacob

in West Greenland. In a newly started PhD-project the focus will be the implementation of spatially explicit individual based modeling (IBM). The project relies on existing knowledge on caribou behavior and feeding ecology along with data on variations in the vegetation. By relating vegetation, snow......Spatial distribution of caribou (Rangifer tarandus groenlandicus) in West Greenland is a result of both short and long term changes in the Arctic landscape. To understand present distribution 40 satellite collars were deployed on 40 female caribou in the Akia-Maniitsoq herd, central West Greenland...... in an area. Further, enhanced or lowered hunting pressure, and changed weather conditions can be studied using IBM. Thus, both short and long term changes in the landscape will be studied and provide insights in how the specific spatial changes impact caribou in West Greenland....

Tracing And Control Of Engineering Requirements

Science.gov (United States)

Turner, Philip R.; Stoller, Richard L.; Neville, Ted; Boyle, Karen A.

1991-01-01

TRACER (Tracing and Control of Engineering Requirements) is data-base/word-processing software system created to document and maintain order of both requirements and descriptions associated with engineering project. Implemented on IBM PC under PC-DOS. Written with CLIPPER.

75 FR 57396 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

Science.gov (United States)

2010-09-21

... 150 ...... ...... Chevrolet Astro Van 1997 298 ...... ...... Chevrolet Blazer 1986 405... (MC) FX, FL, XL Series..... 1998 253 ...... ...... Harley Davidson (MC) FX, FL, XL Series..... 1999 281 ...... ...... Harley Davidson (MC) FX, FL, XL Series..... 2000 321 ...... ...... Harley Davidson...

Fulltext PDF

Indian Academy of Sciences (India)

The computer facilities at PRL consist of 5 IBM RS 6000/580 servers with .... Udaipur Solar Observatory located on an island in term (six to eight weeks) project ... Application Oriented Opportunities: PRL offers opportunities for B Tech (8th ...

Software Technology for Adaptable, Reliable Systems (STARS) Technical Program Plan,

Science.gov (United States)

1986-08-06

Shadow projects that are being considered by the SEI: Service Project Company . . Army FATDS Magnavox CSS To Be Determined PLRS Hughes Navy BSY-I IBM...ISCS Rockwell ACDS Hughes Air Force Simulators Boeing CSSR GTE ATF Grumman MILSTAR Lockheed Figure 4-2 Candidate FY 1986 Shadow Projects 4.2.3 SHADOW...Journal of the Armed Forces Communications and Electronic Association, September 1985. 11. Schill, J., Smeaton, R., and Jackman , R., The Conversion of

Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa

Directory of Open Access Journals (Sweden)

Sheffield William P

2011-12-01

Full Text Available Abstract Background The transglutaminase activated factor XIII (FXIIIa acts to strengthen pathological fibrin clots and to slow their dissolution, in part by crosslinking active α2-antiplasmin (α2AP to fibrin. We previously reported that a yeast-derived recombinant fusion protein comprising α2AP residues 13-42 linked to human serum albumin (HSA weakened in vitro clots but failed to become specifically incorporated into in vivo clots. In this study, our aims were to improve both the stability and clot localization of the HSA fusion protein by replacing α2AP residues 13-42 with shorter sequences recognized more effectively by FXIIIa. Results Expression plasmids were prepared encoding recombinant HSA with the following N-terminal 23 residue extensions: H6NQEQVSPLTLLAG4Y (designated XL1; H6DQMMLPWAVTLG4Y (XL2; H6WQHKIDLPYNGAG4Y (XL3; and their 17 residue non-His-tagged equivalents (XL4, XL5, and XL6. The HSA moiety of XL4- to XL6-HSA proteins was C-terminally His-tagged. All chimerae were efficiently secreted from transformed Pichia pastoris yeast except XL3-HSA, and following nickel chelate affinity purification were found to be intact by amino acid sequencing, as was an N-terminally His-tagged version of α2AP(13-42-HSA. Of the proteins tested, XL5-HSA was cross-linked to biotin pentylamine (BPA most rapidly by FXIIIa, and was the most effective competitor of α2AP crosslinking not only to BPA but also to plasma fibrin clots. In the mouse ferric chloride vena cava thrombosis model, radiolabeled XL5-HSA was retained in the clot to a greater extent than recombinant HSA. In the rabbit jugular vein stasis thrombosis model, XL5-HSA was also retained in the clot, in a urea-insensitive manner indicative of crosslinking to fibrin, to a greater extent than recombinant HSA. Conclusions Fusion protein XL5-HSA (DQMMLPWAVTLG4Y-HSAH6 was found to be more active as a substrate for FXIIIa-mediated transamidation than seven other candidate fusion proteins in

77 FR 59829 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

Science.gov (United States)

2012-10-01

... Cimarron 2006-2007 ..... ..... 37 trailer. Chevrolet 400SS 1995 150 ..... ..... Chevrolet Astro Van... ..... ..... Harley Davidson (MC)......... FX, FL, XL & VR 2004 422 ..... ..... Series. Harley Davidson (MC)......... FX, FL, XL & VR 2008 517 ..... ..... Series. Harley Davidson (MC)......... FX, FL, XL & VR 2009 522...

Isolation of anonymous DNA sequences from within a submicroscopic X chromosomal deletion in a patient with choroideremia, deafness, and mental retardation

International Nuclear Information System (INIS)

Nussbaum, R.L.; Lesko, J.G.; Lewis, R.A.; Ledbetter, S.A.; Ledbetter, D.H.

1987-01-01

Choroideremia, an X-chromosome linked retinal dystrophy of unknown pathogenesis, causes progressive nightblindness and eventual central blindness in affected males by the third to fourth decade of life. Choroideremia has been mapped to Xq13-21 by tight linkage to restriction fragment length polymorphism loci. The authors have recently identified two families in which choroideremia is inherited with mental retardation and deafness. In family XL-62, an interstitial deletion Xq21 is visible by cytogenetic analysis and two linked anonymous DNA markers, DXYS1 and DXS72, are deleted. In the second family, XL-45, an interstitial deletion was suspected on phenotypic grounds but could not be confirmed by high-resolution cytogenetic analysis. They used phenol-enhanced reassociation of 48,XXXX DNA in competition with excess XL-45 DNA to generate a library of cloned DNA enriched for sequences that might be deleted in XL-45. Two of the first 83 sequences characterized from the library were found to be deleted in probands from family XL-45 as well as from family XL-62. Isolation of these sequences proves that XL-45 does contain a submicroscopic deletion and provides a starting point for identifying overlapping genomic sequences that span the XL-45 deletion. Each overlapping sequence will be studied to identify exons from the choroideremia locus

Comparison of three methods of tonometry in normal subjects: Goldmann applanation tonometer, non-contact airpuff tonometer, and Tono-Pen XL

Directory of Open Access Journals (Sweden)

Yilmaz I

2014-06-01

Full Text Available Ihsan Yilmaz, Cigdem Altan, Ebru Demet Aygit, Cengiz Alagoz, Okkes Baz, Sibel Ahmet, Semih Urvasizoglu, Dilek Yasa, Ahmet DemirokBeyoglu Eye Training and Research Hospital, Istanbul, TurkeyObjective: We aimed to compare intraocular pressure (IOP measurements via three different tonometers: the Goldmann applanation tonometer (GAT, the Tono-Pen® XL (TPXL, and a non-contact airpuff tonometer (NCT.Methods: This was a cross-sectional study of 200 eyes from 200 patients. Right eyes of all patients were included in this study. IOP was measured via GAT, NCT, and TPXL by three physicians. Each physician used one of the tonometers. Measurements via the three devices were compared.Results: The mean IOP was 15.5±2.2 mmHg (range 10–22 with the GAT, 16.1±3.0 (range 9–25 with the TPXL, and 16.1±2.8 (range 10–26 with the NCT. Bland–Altman analysis showed that the mean difference between measurements from the NCT and the GAT was 0.6±2.3 mmHg. The mean difference between the TPXL and GAT measurements was 0.7±2.5 mmHg. The mean difference between the NCT and TPXL measurements was −0.02±3.0 mmHg. There was no significant difference between the groups according to a one-way analysis of variance (ANOVA test. P-values were 0.998 for NCT–TPXL, 0.067 for NCT–GAT, and 0.059 for TPXL–GAT.Conclusion: The NCT and TPXL provide IOP measurements comparable to those of the gold standard GAT in normotensive eyes.Keywords: tonometry, noncontact tonometry, Goldmann applanation tonometer, Tono-Pen

HPC Colony II Consolidated Annual Report: July-2010 to June-2011

Energy Technology Data Exchange (ETDEWEB)

Jones, Terry R [ORNL

2011-06-01

This report provides a brief progress synopsis of the HPC Colony II project for the period of July 2010 to June 2011. HPC Colony II is a 36-month project and this report covers project months 10 through 21. It includes a consolidated view of all partners (Oak Ridge National Laboratory, IBM, and the University of Illinois at Urbana-Champaign) as well as detail for Oak Ridge. Highlights are noted and fund status data (burn rates) are provided.

Building Watson: An Overview of the DeepQA Project

OpenAIRE

Ferrucci, David; Brown, Eric; Chu-Carroll, Jennifer; Fan, James; Gondek, David; Kalyanpur, Aditya A.; Lally, Adam; Murdock, J. William; Nyberg, Eric; Prager, John; Schlaefer, Nico; Welty, Chris

2010-01-01

IBM Research undertook a challenge to build a computer system that could compete at the human champion level in real time on the American TV Quiz show, Jeopardy! The extent of the challenge includes fielding a real-time automatic contestant on the show, not merely a laboratory exercise. The Jeopardy! Challenge helped us address requirements that led to the design of the DeepQA architecture and the implementation of Watson. After 3 years of intense research and development by a core team of ab...

Multiple-User Microcomputer Technology and Its Application to the Library Environment.

Science.gov (United States)

McCarthy, Cathleen D.

1987-01-01

Demonstrates the ways in which multiuser and multitasking microcomputer systems can be used for the automation of small- to medium-sized library operations. The possibilities afforded by the IBM-PC AT microcomputer are discussed and a sample configuration with estimated cost projections is provided. (EM)

Voice/Data Integration in the PBX (Private Branch Exchange).

Science.gov (United States)

1985-01-01

NUMBER 7. AUTHOR(a) 6. CONTRACT OR GRANT NUMBER(a) Michelle A. Bull * . PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT...37 capability to emulate other data environments such as IBM’s System Network Architechture (SNA) environ- met26 Access outside the PNX system is

An Approach to the Evaluation and Prediction of the Outflow of Bank Deposits Dynamics Using the Big Data Technologies

Directory of Open Access Journals (Sweden)

Sergey Vladimirovich Zapechnikov

2016-03-01

Full Text Available The results of implementation of pilot-project to test IBM Big Data platform for automation of processes of collection, processing and analysis of unstructured big data applied to the individual functional unit of the banking supervision of the Central Bank of Russia is presented.

Integrated flood disaster management and spatial information : Case studies of Netherlands and India

NARCIS (Netherlands)

Ghawana, T. (T.); Kaur, A. (A.); Neuvel, J.M.M. (J.M.M.); Ziatanova, Z. (Z.)

2014-01-01

Int. Arch. Photogramm. Remote Sens. Spatial Inf. Sci., XL-8, 147-154, 2014www.int-arch-photogramm-remote-sens-spatial-inf-sci.net/XL-8/147/2014/doi:10.5194/isprsarchives-XL-8-147-2014Integrated flood disaster management and spatial information: Case studies ofNetherlands and IndiaS. Zlatanova1, T.

Recent Technological Advances in Natural Language Processing and Artificial Intelligence

OpenAIRE

Shah, Nishal Pradeepkumar

2012-01-01

A recent advance in computer technology has permitted scientists to implement and test algorithms that were known from quite some time (or not) but which were computationally expensive. Two such projects are IBM's Jeopardy as a part of its DeepQA project [1] and Wolfram's Wolframalpha[2]. Both these methods implement natural language processing (another goal of AI scientists) and try to answer questions as asked by the user. Though the goal of the two projects is similar, both of them have a ...

Industry Studies 2002: Construction

Science.gov (United States)

2002-01-01

Jacksonville, FL Rotary Club of San Juan, San Juan, PR Tren Urbano Subway Project, San Juan, PR U.S. Army South, San Juan, PR U.S. Coast Guard Housing Project...Bechtel Corporation (IBM Plant Construction Site), Shanghai American Chamber of Commerce, Shanghai Urban Planning Exhibit, Shanghai 3 INTRODUCTION The...of states have or are working on a statewide or agency-wide privatization plan , including California, Maryland, Massachusetts, Michigan and

Comparison of central corneal thickness and endothelial cell measurements by Scheimpflug camera system and two noncontact specular microscopes.

Science.gov (United States)

Karaca, Irmak; Yilmaz, Suzan Guven; Palamar, Melis; Ates, Halil

2017-07-03

To investigate the correlation of Scheimpflug camera system and two noncontact specular microscopes in terms of central corneal thickness (CCT) and corneal endothelial cell morphology measurements. One hundred eyes of 50 healthy subjects were examined by Pentacam Scheimpflug Analyzer, CEM-530 (Nidek Co, Ltd, Gamagori, Japan) and CellChek XL (Konan Medical, California, USA) via fully automated image analysis with no corrections made. Measurement differences and agreement between instruments were determined by intraclass correlation analysis. The mean age of the subjects was 36.74 ± 8.59 (range 22-57). CCTs were well correlated among all devices, with having CEM-530 the thinnest and CellChek XL the thickest measurements (intraclass correlation coefficient (ICC) = 0.83; p < 0.001 and ICC = 0.78; p < 0.001, respectively). Mean endothelial cell density (ECD) given by CEM-530 was lower than CellChek XL (2613.17 ± 228.62 and 2862.72 ± 170.42 cells/mm 2 , respectively; ICC = 0.43; p < 0.001). Mean value for coefficient of variation (CV) was 28.57 ± 3.61 in CEM-530 and 30.30 ± 3.53 in CellChek XL. Cell hexagonality (HEX) with CEM-530 was higher than with CellChek XL (68.70 ± 4.16% and 45.19 ± 6.58%, respectively). ECDs with CellChek XL and CEM-530 have good correlation, but the values obtained by CellChek XL are higher than CEM-530. Measurements for HEX and CV differ significantly and show weak correlation. Thus, we do not recommend interchangeable use of CellChek XL and CEM-530. In terms of CCTs, Pentacam, CEM-530 and CellChek XL specular microscopy instruments are reliable devices.

78 FR 54182 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

Science.gov (United States)

2013-09-03

... Chevrolet Astro Van 1997 298 Chevrolet Blazer (plant code of ``K'' or 1997 349 ``2'' in the 11th position of...) FL Series 2010 528 Harley Davidson (MC) FX, FL, XL & VR Series......... 2004 422 Harley Davidson (MC) FX, FL, XL & VR Series......... 2008 517 Harley Davidson (MC) FX, FL, XL & VR Series......... 2009...

Essential oil from the leaves of Xylopia langsdorfiana (Annonaceae) as a possible spasmolytic agent.

Science.gov (United States)

Correia, Ana Carolina de C; Ferreira, Tamyris F; Martins, Italo Rossi R; Macêdo, Cibério L; Monteiro, Fabio de S; Costa, Vicente Carlos O; Tavares, Josean F; Silva, Marcelo S; Paredes-Gamero, Edgar J; Buri, Marcus V; Rigoni, Vera L S; Nouailhetas, Viviane L A; Da Silva, Bagnólia A

2015-01-01

Xylopia langsdorfiana A. St.-Hil. &Tul. (Annonaceae) is popularly known in the northeast of Brazil as 'pimenteira da terra', and an essential oil (XL-OE) was extracted from its leaves. Since Xylopia species are cited in folk medicine and diterpenes from X. langsdorfiana have spasmolytic activity, this study aimed to investigate a possible spasmolytic action of XL-OE on smooth muscle models. XL-OE (243 and 729 μg/mL) showed low pharmacologic efficacy on guinea pig trachea and rat aorta and uterus. However, in guinea pig ileum, XL-OE (27-729 μg/mL) inhibited carbachol or histamine-induced phasic contractions (1 μM) in a significant and concentration-dependent manner. In addition, XL-OE (81 μg/mL) reduced fluorescence intensity in ileal myocytes stimulated by histamine, indicating a decrease in cytosolic calcium concentration, which could explain the spasmolytic activity. Thus, XL-OE proved to be a promising natural product to be used in gastrointestinal diseases acting by modulating the cytosolic calcium concentration.

Concurrent Programming Using Actors: Exploiting Large-Scale Parallelism,

Science.gov (United States)

1985-10-07

ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK* Artificial Inteligence Laboratory AREA Is WORK UNIT NUMBERS 545 Technology Square...D-R162 422 CONCURRENT PROGRMMIZNG USING f"OS XL?ITP TEH l’ LARGE-SCALE PARALLELISH(U) NASI AC E Al CAMBRIDGE ARTIFICIAL INTELLIGENCE L. G AGHA ET AL...RESOLUTION TEST CHART N~ATIONAL BUREAU OF STANDA.RDS - -96 A -E. __ _ __ __’ .,*- - -- •. - MASSACHUSETTS INSTITUTE OF TECHNOLOGY ARTIFICIAL

Construction. A Report on the Industry

Science.gov (United States)

2004-06-01

Transportation and Tres Urbano Subway Project, San Juan, Puerto Rico U.S. Corps of Engineers, San Juan, Puerto Rico U.S. Corps of Engineers, Mobile...recently approved a plan to privatize construction of over 6,000 miles of expressways through the use of a build, transfer, and operate options.xl...security standards in Federal facilities, including an aggressive plan to build and renovate embassies and consular offices worldwide.xlv The

77 FR 16579 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2012-03-21

... from ``Phlx XL II'' to ``PHLX XL'' for branding purposes. The text of the proposed rule change is..., for the purpose of executing a particular investment strategy. A Complex Order can also be a stock... set at 10%, and a PHLX XL participant submits a Complex Order with a strategy to buy Series A and buy...

49 CFR Appendix A to Part 593 - List of Vehicles Determined To Be Eligible for Importation

Science.gov (United States)

2010-10-01

... 900 1999 444 Carrocerias Cimarron trailer 2006-2007 37 Chevrolet 400SS 1995 150 Chevrolet Astro Van... Freightliner FTLD112064SD 1991-1996 178 GMC Suburban 1992-1994 134 Harley Davidson (MC) FX, FL, XL Series 1998 253 Harley Davidson (MC) FX, FL, XL Series 1999 281 Harley Davidson (MC) FX, FL, XL Series 2000 321...

Statistical Moments in Variable Density Incompressible Mixing Flows

Science.gov (United States)

2015-08-28

59]. The algorithm uses an approximate projection method [16] with the interface modeled with the Immersed Boundary Method ( IBM ), as spread via a nu...and B. C. Watson . Taylor instability of finite surface waves. J. Fluid Mech., 7:177–193, 1960. [32] E. Fermi. Taylor instability of an

KidSmart© in Early Childhood Learning Practices

DEFF Research Database (Denmark)

Petersson, Eva; Borum, Nanna

2014-01-01

This paper reports on a study exploring the outcomes from young children’s play with digital technology in formal and semi-formal learning practices. The study is part of a bigger project being conducted by IBM KidSmart Early Learning Program, Denmark, the Danish Agency of Culture, 13 kindergartens...

Management Information System Project. Data Processors Manual to the Program Oriented Accounting System: The Budgetary Process.

Science.gov (United States)

Foley, Walter; Harr, Gordon

The purpose of this manual is to serve the needs of a data processing facility in the operation of a management information system (MIS). Included in the manual are system flowcharts, job control language, and system documentation. The system has been field tested and operates under IBM System 360/Model 65-05-MVT-HASP. The programing language is…

Parallel solution of the time-dependent Ginzburg-Landau equations and other experiences using BlockComm-Chameleon and PCN on the IBM SP, Intel iPSC/860, and clusters of workstations

International Nuclear Information System (INIS)

Coskun, E.

1995-09-01

Time-dependent Ginzburg-Landau (TDGL) equations are considered for modeling a thin-film finite size superconductor placed under magnetic field. The problem then leads to the use of so-called natural boundary conditions. Computational domain is partitioned into subdomains and bond variables are used in obtaining the corresponding discrete system of equations. An efficient time-differencing method based on the Forward Euler method is developed. Finally, a variable strength magnetic field resulting in a vortex motion in Type II High T c superconducting films is introduced. The authors tackled the problem using two different state-of-the-art parallel computing tools: BlockComm/Chameleon and PCN. They had access to two high-performance distributed memory supercomputers: the Intel iPSC/860 and IBM SP1. They also tested the codes using, as a parallel computing environment, a cluster of Sun Sparc workstations

Automated recognition of helium speech. Phase I: Investigation of microprocessor based analysis/synthesis system

Science.gov (United States)

Jelinek, H. J.

1986-01-01

This is the Final Report of Electronic Design Associates on its Phase I SBIR project. The purpose of this project is to develop a method for correcting helium speech, as experienced in diver-surface communication. The goal of the Phase I study was to design, prototype, and evaluate a real time helium speech corrector system based upon digital signal processing techniques. The general approach was to develop hardware (an IBM PC board) to digitize helium speech and software (a LAMBDA computer based simulation) to translate the speech. As planned in the study proposal, this initial prototype may now be used to assess expected performance from a self contained real time system which uses an identical algorithm. The Final Report details the work carried out to produce the prototype system. Four major project tasks were: a signal processing scheme for converting helium speech to normal sounding speech was generated. The signal processing scheme was simulated on a general purpose (LAMDA) computer. Actual helium speech was supplied to the simulation and the converted speech was generated. An IBM-PC based 14 bit data Input/Output board was designed and built. A bibliography of references on speech processing was generated.

Development of an On-Line Surgeon-Specific Operating Room Time Prediction System (Experience with the Michigan Surgical Monitors)

OpenAIRE

Brown, Allan C.D.; Schmidt, Nancy M.

1984-01-01

The development of a micro-computer application for the on-line prediction of surgeon-specific operating room time using an IBM - PCXT is described. The reasons leading to the project, together with an assessment of the Condor 20 relational database management system as the basis for the application are discussed.

Identification and mapping of conserved ortholog set(COS) II sequences of cacao and their conversion to SNP markers for marker-assisted selection in Theobroma cocoa and comparative genomics studies

Science.gov (United States)

Theobroma cacao is a tree cultivated in the tropics around the world for its seeds that are the source of both chocolate and cocoa butter. The cacao genome sequencing project initiated as a collaboration between USDA, Mars, Inc. and IBM has generated a great deal of transcriptome and genome sequenc...

Selectie van Italiaanse werkwoordsvormen op basis van frequentieonderzoek

NARCIS (Netherlands)

Boer, M.G. de

2009-01-01

SAMENVATTING Dit artikel is een vroege recensie (mei 1972) van het LIF, de frequentielijst van IBM Italia uit 1971. De auteur concentreert zich op de verschillen met het project van Juilland, dat als uitgangspunt voor het LIF heeft gefungeerd. Op grond van de gegevens van het LIF is een basislijst

Information and image integration: project spectrum

Science.gov (United States)

Blaine, G. James; Jost, R. Gilbert; Martin, Lori; Weiss, David A.; Lehmann, Ron; Fritz, Kevin

1998-07-01

The BJC Health System (BJC) and the Washington University School of Medicine (WUSM) formed a technology alliance with industry collaborators to develop and implement an integrated, advanced clinical information system. The industry collaborators include IBM, Kodak, SBC and Motorola. The activity, called Project Spectrum, provides an integrated clinical repository for the multiple hospital facilities of the BJC. The BJC System consists of 12 acute care hospitals serving over one million patients in Missouri and Illinois. An interface engine manages transactions from each of the hospital information systems, lab systems and radiology information systems. Data is normalized to provide a consistent view for the primary care physician. Access to the clinical repository is supported by web-based server/browser technology which delivers patient data to the physician's desktop. An HL7 based messaging system coordinates the acquisition and management of radiological image data and sends image keys to the clinical data repository. Access to the clinical chart browser currently provides radiology reports, laboratory data, vital signs and transcribed medical reports. A chart metaphor provides tabs for the selection of the clinical record for review. Activation of the radiology tab facilitates a standardized view of radiology reports and provides an icon used to initiate retrieval of available radiology images. The selection of the image icon spawns an image browser plug-in and utilizes the image key from the clinical repository to access the image server for the requested image data. The Spectrum system is collecting clinical data from five hospital systems and imaging data from two hospitals. Domain specific radiology imaging systems support the acquisition and primary interpretation of radiology exams. The spectrum clinical workstations are deployed to over 200 sites utilizing local area networks and ISDN connectivity.

AMDLIBAE, IBM 360 Subroutine Library, Special Function, Polynomials, Differential Equation

International Nuclear Information System (INIS)

Wang, Jesse Y.

1980-01-01

Description of problem or function: AMDLIBAE is a subset of the IBM 360 Subroutine Library at the Applied Mathematics Division at Argonne National Laboratory. This subset includes library categories A-E: Identification/Description: A152S A MPA: Mult. prec. floating point arith. package; B156S A ARSIN: Arcsine, arccosine; B158S A DSIN/DCOS: DP sine, cosine; B159S A DTAN/DCOT: DP tangent, cotangent; B252S A SINH/COSH: Hyperbolic sine, cosine; B353S A ALOG: SP logarithm; B354S A DEXP: DP exponential; B355S A DLOG: DP logarithm; B456S A DCUBRT: DP cube root; B457S A ARGPOWER: X Y ; B458S A ARGFDXPD: DP X Y ; C150S F DQD: Q. D. algorithm applied to a power series; C151S F DCONF1: Eval. cont. fract. Q. D. of power series; C250S F CUBIC: Roots of cubic polynomial equation; C251S F QUARTIC: Roots of quartic polynomial equation; C252S F RSSR: All roots of poly eqs. with real coef.; C253S F POLDRV: Driver for C254S; C254S F CPOLY: Roots arb. poly. Jenkins-Traub algorithm; C353S F1 CLEBSH: Ang. mom. coef. - Clebsch, Racah, Wigner; C365S A ALGAMA: Logarithm of the gamma function; C366S A DGAMMA/DLGAMA: DP gamma and log(gamma) functions; C368S F EONE: Exponential integral E1; C370S F BESJY: Bessel functions J and Y; C371S F BESIK: Bessel functions I and K; C372S F CHIPRB: Chi-square integral; C380S F DRZETA: Long precision zeta, zeta-1 functions; C382S F DCGAM: Long precision complex gamma; C383S A DERF/DERFC: DP error function; C384S F BFJ1: Bessel function J1; C385S F COULMB: Regular Coulomb wave functions; C386S F1 DSGMAL: Coulomb phase shift; C387S F BFJYR: Bessel functions J0,J1,Y0,Y1; C388S F IRCOUL: LP irregular Coulomb wave functions; C389S F GAMIN: Incomplete gamma function; C390S F LQ: Assoc. Legendre functions of 2. kind; C392S A DAERF: Inverse error function; C393S F CDEONE: Modified complex exponential integral; D153S F DROMB: Two-dimensional Romberg quadrature; D153S P DROMBP: Two-dimensional Romberg quadrature; D158S F ANC4: Adap. quad. using 4. order Newton

Interface card for NMR data acquisition; Cartao de aquisicao de dados para RMN

Energy Technology Data Exchange (ETDEWEB)

Torre Neto, Andre; Colnago, Luiz Alberto [Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA), Sao Carlos, SP (Brazil). Nucleo de Pesquisa e Desenvolvimento de Instrumentacao Agropecuaria

1992-12-31

A NMR spectrometer constructed by NPDIA is being used for analysis of seed oil contents in projects of oil seeds improvement. Some improvements have been introduced in this spectrometer, and this work presents an IBM-Pc compatible interface card. This interface has some characteristics which are exclusive for NMR 6 refs., 3 figs.

Large-Scale Campus Computer Technology Implementation: Lessons from the First Year.

Science.gov (United States)

Nichols, Todd; Frazer, Linda H.

The purpose of the Elementary Technology Demonstration Schools (ETDS) Project, funded by IBM and Apple, Inc., was to demonstrate the effectiveness of technology in accelerating the learning of low achieving at-risk students and enhancing the education of high achieving students. The paper begins by giving background information on the district,…

Engraftment Efficiency after Intra-Bone Marrow versus Intravenous Transplantation of Bone Marrow Cells in a Canine Nonmyeloablative Dog Leukocyte Antigen-Identical Transplantation Model.

Science.gov (United States)

Lange, Sandra; Steder, Anne; Killian, Doreen; Knuebel, Gudrun; Sekora, Anett; Vogel, Heike; Lindner, Iris; Dunkelmann, Simone; Prall, Friedrich; Murua Escobar, Hugo; Freund, Mathias; Junghanss, Christian

2017-02-01

An intra-bone marrow (IBM) hematopoietic stem cell transplantation (HSCT) is assumed to optimize the homing process and therefore to improve engraftment as well as hematopoietic recovery compared with conventional i.v. HSCT. This study investigated the feasibility and efficacy of IBM HSCT after nonmyeloablative conditioning in an allogeneic canine HSCT model. Two study cohorts received IBM HSCT of either density gradient (IBM-I, n = 7) or buffy coat (IBM-II, n = 6) enriched bone marrow cells. An historical i.v. HSCT cohort served as control. Before allogeneic HSCT experiments were performed, we investigated the feasibility of IBM HSCT by using technetium-99m marked autologous grafts. Scintigraphic analyses confirmed that most IBM-injected autologous cells remained at the injection sites, independent of the applied volume. In addition, cell migration to other bones occurred. The enrichment process led to different allogeneic graft volumes (IBM-I, 2 × 5 mL; IBM-II, 2 × 25 mL) and significantly lower counts of total nucleated cells in IBM-I grafts compared with IBM-II grafts (1.6 × 10 8 /kg versus 3.8 × 10 8 /kg). After allogeneic HSCT, dogs of the IBM-I group showed a delayed engraftment with lower levels of donor chimerism when compared with IBM-II or to i.v. HSCT. Dogs of the IBM-II group tended to reveal slightly faster early leukocyte engraftment kinetics than intravenously transplanted animals. However, thrombocytopenia was significantly prolonged in both IBM groups when compared with i.v. HSCT. In conclusion, IBM HSCT is feasible in a nonmyeloablative HSCT setting but failed to significantly improve engraftment kinetics and hematopoietic recovery in comparison with conventional i.v. HSCT. Copyright © 2017 The American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

BIM-Mediated Membrane Insertion of the BAK Pore Domain Is an Essential Requirement for Apoptosis

Directory of Open Access Journals (Sweden)

Kathrin Weber

2013-10-01

Full Text Available BAK activation represents a key step during apoptosis, but how it converts into a mitochondria-permeabilizing pore remains unclear. By further delineating the structural rearrangements involved, we reveal that BAK activation progresses through a series of independent steps: BH3-domain exposure, N-terminal change, oligomerization, and membrane insertion. Employing a “BCL-XL-addiction” model, we show that neutralization of BCL-XL by the BH3 mimetic ABT-737 resulted in death only when cells were reconstituted with BCL-XL:BAK, but not BCL-2/ BCL-XL:BIM complexes. Although this resembles the indirect model, release of BAK from BCL-XL did not result in spontaneous adoption of the pore conformation. Commitment to apoptosis required association of the direct activator BIM with oligomeric BAK promoting its conversion to a membrane-inserted pore. The sequential nature of this cascade provides multiple opportunities for other BCL-2 proteins to interfere with or promote BAK activation and unites aspects of the indirect and direct activation models.

FRET two-hybrid assay by linearly fitting FRET efficiency to concentration ratio between acceptor and donor

Science.gov (United States)

Du, Mengyan; Yang, Fangfang; Mai, Zihao; Qu, Wenfeng; Lin, Fangrui; Wei, Lichun; Chen, Tongsheng

2018-04-01

We here introduce a fluorescence resonance energy transfer (FRET) two-hybrid assay method to measure the maximal donor(D)- and acceptor(A)-centric FRET efficiency (ED,max and EA,max) of the D-A complex and its stoichiometry by linearly fitting the donor-centric FRET efficiency (ED) to the acceptor-to-donor concentration ratio (RC) and acceptor-centric FRET efficiency (EA) to 1/RC, respectively. We performed this method on a wide-field fluorescence microscope for living HepG2 cells co-expressing FRET tandem constructs and free donor/acceptor and obtained correct ED, EA, and stoichiometry values of those tandem constructs. Evaluation on the binding of Bad with Bcl-XL in Hela cells showed that Bad interacted strongly with Bcl-XL to form a Bad-Bcl-XL complex on mitochondria, and one Bad interacted mainly with one Bcl-XL molecule in healthy cells, while with multiple (maybe 2) Bcl-XL molecules in apoptotic cells.

The SIMRAND 1 computer program: Simulation of research and development projects

Science.gov (United States)

Miles, R. F., Jr.

1986-01-01

The SIMRAND I Computer Program (Version 5.0 x 0.3) written in Microsoft FORTRAN for the IBM PC microcomputer and its compatibles is described. The SIMRAND I Computer Program comprises eleven modules-a main routine and ten subroutines. Two additional files are used at compile time; one inserts the system or task equations into the source code, while the other inserts the dimension statements and common blocks. The SIMRAND I Computer Program can be run on most microcomputers or mainframe computers with only minor modifications to the computer code.

Solar energy system economic evaluation for IBM System 3, Glendo, Wyoming

Science.gov (United States)

1980-01-01

This analysis was based on the technical and economic models in f-chart design procedures with inputs based on the characteristics of the parameters of present worth of system cost over a projected twenty year life: life cycle savings, year of positive savings, and year of payback for the optimized solar energy system at each of the analysis sites. The sensitivity of the economic evaluation to uncertainties in constituent system and economic variables was also investigated.

The influence of central corneal thickness and age on intraocular pressure measured by pneumotonometry, non-contact tonometry, the Tono-Pen XL, and Goldmann applanation tonometry.

Science.gov (United States)

Tonnu, P-A; Ho, T; Newson, T; El Sheikh, A; Sharma, K; White, E; Bunce, C; Garway-Heath, D

2005-07-01

To evaluate the influence of central corneal thickness (CCT) on intraocular pressure (IOP) measurements made with the Goldmann applanation tonometer (GAT), Tono-Pen XL, ocular blood flow tonograph (OBF), and Canon TX-10 non-contact tonometer (NCT). CCT was recorded for either eye (randomly selected) of each of 105 untreated patients with ocular hypertension and glaucoma attending the glaucoma research unit at Moorfields Eye Hospital. For each of the selected eyes, IOP was measured with the GAT (two observers), Tono-Pen, OBF, and NCT in a randomised order. The relation of measured IOP and of inter-tonometer differences with CCT and subject age was explored by linear regression analysis. A significant association between measured IOP and CCT was found with each instrument. The change in measured IOP for a 10 mum increase in CCT was 0.28, 0.31, 0.38, and 0.46 for the GAT, Tono-Pen, OBF, and NCT, respectively (all p< or = 0.05). There was a significant association between the NCT/GAT differences and CCT, with a tendency of NCT to overestimate GAT in eyes with thicker corneas. There was a significant association between GAT/Tono-Pen and OBF/Tono-Pen differences and age, with a tendency of GAT and OBF to overestimate the Tono-Pen in eyes of older subjects. IOP measurement by all four methods is affected by CCT. The NCT is affected by CCT significantly more than the GAT. Subject age has a differential effect on the IOP measurements made by the GAT and OBF compared to the Tono-Pen.

Vatican Library Automates for the 21st Century.

Science.gov (United States)

Carter, Thomas L.

1994-01-01

Because of space and staff constraints, the Vatican Library can issue only 2,000 reader cards a year. Describes IBM's Vatican Library Project: converting the library catalog records (prior to 1985) into machine readable form and digitally scanning 20,000 manuscript pages, print pages, and art works in gray scale and color, creating a database…

Computer-Assisted Instruction in the N.W.T.

Science.gov (United States)

Garraway, Tom

For the past seven years, the Division of Educational Research Services at the University of Alberta has been operating an IBM 1500 CAI system. This paper describes demonstration projects set up in anticipation of the establishment of remote CAI in the North West Territories. These include a moon landing simulation program; a diagnostic program in…

Scalability of Parallel Spatial Direct Numerical Simulations on Intel Hypercube and IBM SP1 and SP2

Science.gov (United States)

Joslin, Ronald D.; Hanebutte, Ulf R.; Zubair, Mohammad

1995-01-01

The implementation and performance of a parallel spatial direct numerical simulation (PSDNS) approach on the Intel iPSC/860 hypercube and IBM SP1 and SP2 parallel computers is documented. Spatially evolving disturbances associated with the laminar-to-turbulent transition in boundary-layer flows are computed with the PSDNS code. The feasibility of using the PSDNS to perform transition studies on these computers is examined. The results indicate that PSDNS approach can effectively be parallelized on a distributed-memory parallel machine by remapping the distributed data structure during the course of the calculation. Scalability information is provided to estimate computational costs to match the actual costs relative to changes in the number of grid points. By increasing the number of processors, slower than linear speedups are achieved with optimized (machine-dependent library) routines. This slower than linear speedup results because the computational cost is dominated by FFT routine, which yields less than ideal speedups. By using appropriate compile options and optimized library routines on the SP1, the serial code achieves 52-56 M ops on a single node of the SP1 (45 percent of theoretical peak performance). The actual performance of the PSDNS code on the SP1 is evaluated with a "real world" simulation that consists of 1.7 million grid points. One time step of this simulation is calculated on eight nodes of the SP1 in the same time as required by a Cray Y/MP supercomputer. For the same simulation, 32-nodes of the SP1 and SP2 are required to reach the performance of a Cray C-90. A 32 node SP1 (SP2) configuration is 2.9 (4.6) times faster than a Cray Y/MP for this simulation, while the hypercube is roughly 2 times slower than the Y/MP for this application. KEY WORDS: Spatial direct numerical simulations; incompressible viscous flows; spectral methods; finite differences; parallel computing.

Imprinted-like biopolymeric micelles as efficient nanovehicles for curcumin delivery.

Science.gov (United States)

Zhang, Lili; Qi, Zeyou; Huang, Qiyu; Zeng, Ke; Sun, Xiaoyi; Li, Juan; Liu, You-Nian

2014-11-01

To enhance the solubility and improve the bioavailability of hydrophobic curcumin, a new kind of imprinted-like biopolymeric micelles (IBMs) was designed. The IBMs were prepared via co-assembly of gelatin-dextran conjugates with hydrophilic tea polyphenol, then crosslinking the assembled micelles and finally removing the template tea polyphenol by dialysis. The obtained IBMs show selective binding for polyphenol analogous drugs over other drugs. Furthermore, curcumin can be effectively encapsulated into the IBMs with 5×10(4)-fold enhancement of aqueous solubility. We observed the sustained drug release behavior from the curcumin-loaded IBMs (CUR@IBMs) in typical biological buffers. In addition, we found the cell uptake of CUR@IBMs is much higher than that of free curcumin. The cell cytotoxicity results illustrated that CUR@IBMs can improve the growth inhibition of HeLa cells compared with free curcumin, while the blank IBMs have little cytotoxicity. The in vivo animal study demonstrated that the IBMs could significantly improve the oral bioavailability of curcumin. Copyright © 2014 Elsevier B.V. All rights reserved.

76 FR 53525 - Final Environmental Impact Statement for the Proposed Keystone XL Project; Public Meetings

Science.gov (United States)

2011-08-26

..., September 26, 2011 Bob Bowers Civic Center, 3401 Cultural Center Drive, Port Arthur, Texas 77642, 4:30 p.m.-10 p.m. Kansas Expo Center, 1 Expocenter Drive, Topeka, Kansas 66612, 12 p.m.- 3:30 p.m., 4 p.m.-8 p.m. Tuesday, September 27, 2011 Dawson Community College, Toepke Center Auditorium, 300 Community...

76 FR 55157 - Final Public Meeting in Washington, DC for the Proposed Keystone XL Project

Science.gov (United States)

2011-09-06

..., including environmental, economic, energy security, foreign policy, and pipeline safety concerns. No... and analysis of the national interest, on August 26, 2011 the U.S. Department of State announced..., Bureau of Oceans and International Environmental and Scientific Affairs/Office of Environmental Policy, U...

G.M.S.I. - A generalised multigroup system of calculations using the IBM 7030 (stretch) computer

International Nuclear Information System (INIS)

Gratton, C.P.; Smith, P.E.

1965-02-01

G.M.S. is a generalised system of reactor physics calculations written in the FORTRAN programming language for the IBM 7030 (STRETCH) computer. The programme will perform cell, supercell and overall reactor physics problems within the limits of one dimension using either slab or cylindrical geometry. The Winfrith DSN(1) programme has been incorporated as a subroutine and all flux distribution calculations are performed using Transport Theory. A facility for the study of fuel burn-up has been included with boundary conditions for either cell irradiations or the burn-up characteristics of the overall reactor. Particular attention has been paid to the simplicity of the input to the programme to allow a wide range of potential users and extensive edit facilities have been incorporated to allow the better understanding of the multigroup output. A graphical output option is available using the STROMBERG-CARLSON equipment and, by a series of commands, graphs of power peaking and burn-up rates are produced for the designer or, alternatively, neutron spectra and activations for comparison with experiment, The logic of the programme is written in terms of 40 neutron energy groups, the group boundaries of which may be selected by the user. Clearly the use of the system for fast reactor calculations requires that greater emphasis be given to the representation of neutron events at high energy than would be necessary for thermal reactor studies. It is envisaged therefore that eventually two library files will be made available to cover the extreme cases of fast and thermal systems and that the group boundaries of these will be selected to enable adequate treatment of intermediate spectrum reactors. At the present time the thermal reactor library file only has been prepared; the content of this library is discussed in Section 2. The group structure is comprised of twelve groups in the fast and intermediate energy region, ten groups in and around the plutonium 240 resonance at 1

"Less Clicking, More Watching": Results from the User-Centered Design of a Multi-Institutional Web Site for Art and Culture.

Science.gov (United States)

Vergo, John; Karat, Clare-Marie; Karat, John; Pinhanez, Claudio; Arora, Renee; Cofino, Thomas; Riecken, Doug; Podlaseck, Mark

This paper summarizes a 10-month long research project conducted at the IBM T.J. Watson Research Center aimed at developing the design concept of a multi-institutional art and culture web site. The work followed a user-centered design (UCD) approach, where interaction with prototypes and feedback from potential users of the web site were sought…

Computer Crafts for Kids.

Science.gov (United States)

Kuntz, Margy; Kuntz, Ann

This work presents a collection of craft projects that can be created by children. Necessary for completion of each craft is an IBM-compatible computer running Windows, "Word for Windows 6.0," with a mouse, a printer, and plain white printer paper. Simple craft supplies, including glue and scissors, also are needed. In each activity the child is…

Reproducibility of Quantitative Structural and Physiological MRI Measurements

Science.gov (United States)

2017-08-09

project.org/) and SPSS (IBM Corp., Armonk, NY) for data analysis. Mean and confidence inter- vals for each measure are found in Tables 1–7. To assess...visits, and was calculated using a two- way mixed model in SPSS MCV and MRD values closer to 0 are considered to be the most reproducible, and ICC

E-trade dossier. Back end: towards a virtual oil company? An application service provider specialized in petroleum applications. Aspentech allies with IBM. The E-trade era has started. France adapts to information technologies; Dossier E-commerce. Aval: vers une compagnie petroliere virtuelle? Un ASP specialise dans les applications petrolieres. Aspentech s'allie a IBM. L'ere de l'E-commerce a commence. La France s'adapte aux technologies de l'information

Energy Technology Data Exchange (ETDEWEB)

Anon.

2000-08-01

This dossier analyzes the expected impact of the electronic business on the petroleum and gas industries. It comprises 5 articles dealing with: the development of E-business in the back end of the petroleum industry for the reduction of costs and the control of the interface with clients, the knowledge data-base portal developed by GeoNet for the supply of softwares to oil and gas industries, the strategic alliance between IBM and Aspen Technology (a supplier of integrated e-business softwares), the launching of a unique global portal on the Web by Schlumberger for the commercialization of oil and gas data and assets, the French government priorities in the development of information technologies in a legal frame. (J.S.)

Integration and Testing Challenges of Small Satellite Missions: Experiences from the Space Technology 5 Project

Science.gov (United States)

Sauerwein, Timothy A.; Gostomski, Tom

2007-01-01

The Space Technology 5(ST5) payload was successfully carried into orbit on an OSC Pegasus XL launch vehicle, which was carried aloft and dropped from the OSC Lockheed L-1011 from Vandenberg Air Force Base March 22,2006, at 9:03 am Eastern time, 6:03 am Pacific time. In order to reach the completion of the development and successful launch of ST 5, the systems integration and test(I&T) team determined that a different approach was required to meet the project requirements rather than the standard I&T approach used for single, room-sized satellites. The ST5 payload, part of NASA's New Millennium Program headquartered at JPL, consisted of three micro satellites (approximately 30 kg each) and the Pegasus Support Structure (PSS), the system that connected the spacecrafts to the launch vehicle and deployed the spacecrafts into orbit from the Pegasus XL launch vehicle. ST5 was a technology demonstration payload, intended to test six (6) new technologies for potential use for future space flights along with demonstrating the ability of small satellites to perform quality science. The main technology was a science grade magnetometer designed to take measurements of the earth's magnetic field. The three spacecraft were designed, integrated, and tested at NASA Goddard Space Flight Center with integration and environmental testing occurring in the Bldg. 7-1 0-15-29. The three spacecraft were integrated and tested by the same I&T team. The I&T Manager determined that there was insufficient time in the schedule to perform the three I&T spacecraft activities in series used standard approaches. The solution was for spacecraft #1 to undergo integration and test first, followed by spacecraft #2 and #3 simultaneously. This simultaneous integration was successful for several reasons. Each spacecraft had a Lead Test Conductor who planned and coordinated their spacecraft through its integration and test activities. One team of engineers and technicians executed the integration of all

Disease: H00849 [KEGG MEDICUS

Lifescience Database Archive (English)

Full Text Available e deficiency; Guanidinoacetate methyltransferase deficiency [DS:H00834]; X-linked creatine deficiency syndrome (XL-CDS) The creatin...e deficiency syndrome is a group of inborn errors of creatine metabolism, that includ...transferase (AGAT) deficiency, and X-linked creatine deficiency syndrome (XL-CDS). Intellectual disability a...nd seizures are common to all three disorders. GAMT deficiency and AGAT deficiency are creatine biosynthesis... disorders and inherited in an autosomal recessive manner. XL-CDS is the creatine

CD-based image archival and management on a hybrid radiology intranet.

Science.gov (United States)

Cox, R D; Henri, C J; Bret, P M

1997-08-01

This article describes the design and implementation of a low-cost image archival and management solution on a radiology network consisting of UNIX, IBM personal computer-compatible (IBM, Purchase, NY) and Macintosh (Apple Computer, Cupertino, CA) workstations. The picture archiving and communications system (PACS) is modular, scaleable and conforms to the Digital Imaging and Communications in Medicine (DICOM) 3.0 standard for image transfer, storage and retrieval. Image data is made available on soft-copy reporting workstations by a work-flow management scheme and on desktop computers through a World Wide Web (WWW) interface. Data archival is based on recordable compact disc (CD) technology and is automated. The project has allowed the radiology department to eliminate the use of film in magnetic resonance (MR) imaging, computed tomography (CT) and ultrasonography.

Social Media Marketing – Analysis of Online presence of Slovak banks

Directory of Open Access Journals (Sweden)

Tomas Feige

2013-07-01

Full Text Available Paper focuses on areas of Social Media Marketing and Social Network Analysis. It describes case-study of joint university-business project of analysis of online presence of Slovak banks which took place in cooperation with IBM CZ in early 2012. This project was aimed at general analysis of online presence of Slovak banks, uncovering the structure of various channels and forms of bank-customer interaction and identifying key actors in banks social networks along with general sentiment and climate. Paper gives a general overview of the project and its challenges and presents high-level results.

rno-miR-665 targets BCL2L1 (Bcl-xl) and increases vulnerability to propofol in developing astrocytes.

Science.gov (United States)

Sun, Wen-Chong; Pei, Ling

2016-07-01

Propofol exerts a cytotoxic influence over immature neurocytes. Our previous study revealed that clinically relevant doses of propofol accelerated apoptosis of primary cultured astrocytes of developing rodent brains via rno-miR-665 regulation. However, the role of rno-miR-665 during the growth spurt of neonatal rodent brains in vivo is still uncertain. Post-natal day 7 (P7) rats received a single injection of propofol 30 mg/kg intraperitoneally (i.p.), and neuroapoptosis of hippocampal astrocytes was analyzed by immunofluorescence and scanning electron microscopy. The differential expression of rno-miR-665, BCL2L1 (Bcl-xl), and cleaved caspase 3 (CC3) was surveyed by qRT-PCR and western blotting. In addition, the utility of A-1155463, a highly potent and BCL2L1-selective antagonist, was aimed to assess the contribution of BCL2L1 for neuroglial survival. Following the intraventricular injection of lentivirus rno-miR-665, neuroprotection was detected by 5-point scale measurement. The single dose of propofol 30 mg/kg triggered dose-dependent apoptosis of developing hippocampal astrocytes. Meanwhile, propofol triggered both rno-miR-665 and CC3, and depressed BCL2L1, which was predicted as one target gene of rno-miR-665. Combination treatment with A-1155463 and propofol induced lower mRNA and protein levels of BCL2L1 and more CC3 activation than propofol treatment alone in vivo. The lentivirus-mediated knockdown of rno-miR-665 elevated BCL2L1 and attenuated CC3 levels, whereas up-regulation of rno-miR-665 suppressed BCL2L1 and induced CC3 expression in vivo. More importantly, rno-miR-665 antagomir infusion improved neurological outcomes of pups receiving propofol during the brain growth spurt. Rno-miR-665, providing a potential target for alternative therapeutics for pediatric anesthesia, is susceptible to propofol by negatively targeting antiapoptotic BCL2L1. Relatively little is known about the association between exposure of astrocytes to brief propofol

78 FR 4926 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2013-01-23

... particular investment strategy. Furthermore, a Complex Order can also be a stock-option order, which is an... that would change all references to the system from ``Phlx XL II'' to ``PHLX XL'' for branding purposes...

The USL NASA PC R and D development environment standards

Science.gov (United States)

Dominick, Wayne D. (Editor); Moreau, Dennis R.

1984-01-01

The development environment standards which have been established in order to control usage of the IBM PC/XT development systems and to prevent interference between projects being currently developed on the PC's are discussed. The standards address the following areas: scheduling PC resources; login/logout procedures; training; file naming conventions; hard disk organization; diskette care; backup procedures; and copying policies.

Comparison of Epson scanner quality for radiochromic film evaluation.

Science.gov (United States)

Alnawaf, Hani; Yu, Peter K N; Butson, Martin

2012-09-06

Epson Desktop scanners have been quoted as devices which match the characteristics required for the evaluation of radiation dose exposure by radiochromic films. Specifically, models such as the 10000XL have been used successfully for image analysis and are recommended by ISP for dosimetry purposes. This note investigates and compares the scanner characteristics of three Epson desktop scanner models including the Epson 10000XL, V700, and V330. Both of the latter are substantially cheaper models capable of A4 scanning. As the price variation between the V330 and the 10000XL is 20-fold (based on Australian recommended retail price), cost savings by using the cheaper scanners may be warranted based on results. By a direct comparison of scanner uniformity and reproducibility we can evaluate the accuracy of these scanners for radiochromic film dosimetry. Results have shown that all three scanners can produce adequate scanner uniformity and reproducibility, with the inexpensive V330 producing a standard deviation variation across its landscape direction of 0.7% and 1.2% in the portrait direction (reflection mode). This is compared to the V700 in reflection mode of 0.25% and 0.5% for landscape and portrait directions, respectively, and 0.5% and 0.8% for the 10000XL. In transmission mode, the V700 is comparable in reproducibility to the 10000XL for portrait and landscape mode, whilst the V330 is only capable of scanning in the landscape direction and produces a standard deviation in this direction of 1.0% compared to 0.6% (V700) and 0.25% (10000XL). Results have shown that the V700 and 10000XL are comparable scanners in quality and accuracy with the 10000XL obviously capable of imaging over an A3 area as opposed to an A4 area for the V700. The V330 scanner produced slightly lower accuracy and quality with uncertainties approximately twice as much as the other scanners. However, the results show that the V330 is still an adequate scanner and could be used for radiation

Effects on microstrain and conversion of flowable resin composite using different curing modes and units.

Science.gov (United States)

Tseng, Wan-Yu; Chen, Ruey-Song; Wang, Jaw-Lin; Lee, Ming-Shu; Rueggeberg, Frederick A; Chen, Min-Huey

2007-05-01

The flowable resin composite, Tetric Flow, was used to measure microstrain and degree of conversion after hardening with each of three curing machines: XL3000(XL) for 10, 20, 30, and 40 s; Optilux 501 using conventional mode (OC) for 10, 20, 30, and 40 s, as well as Optilux boost (OB, 10 s) and ramp modes (OR, 20 s); and LEDemetron (LEDe) for 10, 20, 30, and 40 s. The emitted power density and spectral distribution of the three light curing units were also measured. The LEDe output energy spectrum was centralized between 425 and 490 nm, which encompasses the excited wavelength of camphorquinone. The microstrain produced by the curing process is as a second-degree polynomial for each light source. The OB microstrain was highest, while the OR microstrain was lower. The ranking in order of degree of monomer conversion was as follows: XL10 conversion cured with OB was significant higher than other curing modes except OC30, OC40, LEDe30, LEDe40, and XL40. The conversion value of XL10 was the lowest. The LEDe produced higher conversion for the same emitted energy compared to the two halogen units.

A Novel Multiscale Design of Interfaces for Polymeric Composites and Bonded Joints using Additive Manufacturing

Science.gov (United States)

2016-09-13

ailk1αk1 ∂Vi ∂xl dx2dx3−11 ∫ S ail11 ∂Vi ∂xl dx2dx3 (2.12) Applying divergence theorem on the right hand side∫ Sp ailkβ( ∂Ũk ∂xβ − αkβ∆T ) ∂Vi ∂xl...introducing a trial field V with 11 = 0 and averaging equation (2.2) gives, ∫ Ω ∂σij ∂xj VidΩ = 0, ∀Vi with i=1, 2, 3. (2.6) Applying divergence ... theorem to the above equation yields,∫ Ω σij ∂Vi ∂xj dΩ = ∫ ∑ +L FiVidS − ∫ ∑ −L FiVidS (2.7) Since, Vi does not depend on x1:∫ Ω σil ∂Vi ∂xl dΩ = 0, ∀Vi

3081/E processor

International Nuclear Information System (INIS)

Kunz, P.F.; Gravina, M.; Oxoby, G.

1984-04-01

The 3081/E project was formed to prepare a much improved IBM mainframe emulator for the future. Its design is based on a large amount of experience in using the 168/E processor to increase available CPU power in both online and offline environments. The processor will be at least equal to the execution speed of a 370/168 and up to 1.5 times faster for heavy floating point code. A single processor will thus be at least four times more powerful than the VAX 11/780, and five processors on a system would equal at least the performance of the IBM 3081K. With its large memory space and simple but flexible high speed interface, the 3081/E is well suited for the online and offline needs of high energy physics in the future

STARS: An Integrated, Multidisciplinary, Finite-Element, Structural, Fluids, Aeroelastic, and Aeroservoelastic Analysis Computer Program

Science.gov (United States)

Gupta, K. K.

1997-01-01

A multidisciplinary, finite element-based, highly graphics-oriented, linear and nonlinear analysis capability that includes such disciplines as structures, heat transfer, linear aerodynamics, computational fluid dynamics, and controls engineering has been achieved by integrating several new modules in the original STARS (STructural Analysis RoutineS) computer program. Each individual analysis module is general-purpose in nature and is effectively integrated to yield aeroelastic and aeroservoelastic solutions of complex engineering problems. Examples of advanced NASA Dryden Flight Research Center projects analyzed by the code in recent years include the X-29A, F-18 High Alpha Research Vehicle/Thrust Vectoring Control System, B-52/Pegasus Generic Hypersonics, National AeroSpace Plane (NASP), SR-71/Hypersonic Launch Vehicle, and High Speed Civil Transport (HSCT) projects. Extensive graphics capabilities exist for convenient model development and postprocessing of analysis results. The program is written in modular form in standard FORTRAN language to run on a variety of computers, such as the IBM RISC/6000, SGI, DEC, Cray, and personal computer; associated graphics codes use OpenGL and IBM/graPHIGS language for color depiction. This program is available from COSMIC, the NASA agency for distribution of computer programs.

Improvement of nuclear core power distribution analysis for Ulchin unit 1 and 2

International Nuclear Information System (INIS)

Chang, Jong Hwa; Zee, Sung Kyoon; Lee, Sang Ho; Park, Yong Soo; Lee, Chang Ho; Choi, Young Kil; Kim, Hee Kyung; Cho, Young Sik; Cho, In Hang

1994-12-01

The FMCP package which does the power shape analysis of Framatom type of reactors on IBM mainframe, is migrated to an IBM-PC system. This report describes the related technique and works. An IBM-PC software DAP is developed to replace the plant computer attached 8 inch floppy disk driver to an IBM-PC. Other programs of FMCP, such as CEDRIC, CARIN and ESTHER, are also migrated to an IBM-PC using Lahey Fortran 77 compiler. A few auxiliary programs are also developed for easy handling of FMCP in the IBM-PC environment. This report describes the usage of the developed system as well as the migration related techniques. (Author) 4 figs

Structure of vibrational and rotational nuclei

International Nuclear Information System (INIS)

Otsuka, Takaharu

1980-01-01

The nuclear collective motion is discussed in terms of the Interacting Boson Model (IBM). Results of phenomenological studies by the IBM are presented, and the relation between the IBM and the geometrical models such as the vibration model, the rotor model, etc., is pointed out. A microscopic picture for the IBM is shown, in which bosons are introduced as a tool to describe the motion of nucleon pairs. It is emphasized that the IBM can give a unified understanding of the nuclear collective motion. (author)

Analysis of habitat-selection rules using an individual-based model

Science.gov (United States)

Steven F. Railsback; Bret C. Harvey

2002-01-01

Abstract - Despite their promise for simulating natural complexity,individual-based models (IBMs) are rarely used for ecological research or resource management. Few IBMs have been shown to reproduce realistic patterns of behavior by individual organisms.To test our IBM of stream salmonids and draw conclusions about foraging theory,we analyzed the IBM ’s ability to...

Differences in transcription between free-living and CO2-activated third-stage larvae of Haemonchus contortus

Directory of Open Access Journals (Sweden)

Zhong Weiwei

2010-04-01

Full Text Available Abstract Background The disease caused by Haemonchus contortus, a blood-feeding nematode of small ruminants, is of major economic importance worldwide. The infective third-stage larva (L3 of this gastric nematode is enclosed in a cuticle (sheath and, once ingested with herbage by the host, undergoes an exsheathment process that marks the transition from the free-living (L3 to the parasitic (xL3 stage. This study explored changes in gene transcription associated with this transition and predicted, based on comparative analysis, functional roles for key transcripts in the metabolic pathways linked to larval development. Results Totals of 101,305 (L3 and 105,553 (xL3 expressed sequence tags (ESTs were determined using 454 sequencing technology, and then assembled and annotated; the most abundant transcripts encoded transthyretin-like, calcium-binding EF-hand, NAD(P-binding and nucleotide-binding proteins as well as homologues of Ancylostoma-secreted proteins (ASPs. Using an in silico-subtractive analysis, 560 and 685 sequences were shown to be uniquely represented in the L3 and xL3 stages, respectively; the transcripts encoded ribosomal proteins, collagens and elongation factors (in L3, and mainly peptidases and other enzymes of amino acid catabolism (in xL3. Caenorhabditis elegans orthologues of transcripts that were uniquely transcribed in each L3 and xL3 were predicted to interact with a total of 535 other genes, all of which were involved in embryonic development. Conclusion The present study indicated that some key transcriptional alterations taking place during the transition from the L3 to the xL3 stage of H. contortus involve genes predicted to be linked to the development of neuronal tissue (L3 and xL3, formation of the cuticle (L3 and digestion of host haemoglobin (xL3. Future efforts using next-generation sequencing and bioinformatic technologies should provide the efficiency and depth of coverage required for the determination of the

Evaluation and construction of diagnostic criteria for inclusion body myositis

Science.gov (United States)

Mammen, Andrew L.; Amato, Anthony A.; Weiss, Michael D.; Needham, Merrilee

2014-01-01

Objective: To use patient data to evaluate and construct diagnostic criteria for inclusion body myositis (IBM), a progressive disease of skeletal muscle. Methods: The literature was reviewed to identify all previously proposed IBM diagnostic criteria. These criteria were applied through medical records review to 200 patients diagnosed as having IBM and 171 patients diagnosed as having a muscle disease other than IBM by neuromuscular specialists at 2 institutions, and to a validating set of 66 additional patients with IBM from 2 other institutions. Machine learning techniques were used for unbiased construction of diagnostic criteria. Results: Twenty-four previously proposed IBM diagnostic categories were identified. Twelve categories all performed with high (≥97%) specificity but varied substantially in their sensitivities (11%–84%). The best performing category was European Neuromuscular Centre 2013 probable (sensitivity of 84%). Specialized pathologic features and newly introduced strength criteria (comparative knee extension/hip flexion strength) performed poorly. Unbiased data-directed analysis of 20 features in 371 patients resulted in construction of higher-performing data-derived diagnostic criteria (90% sensitivity and 96% specificity). Conclusions: Published expert consensus–derived IBM diagnostic categories have uniformly high specificity but wide-ranging sensitivities. High-performing IBM diagnostic category criteria can be developed directly from principled unbiased analysis of patient data. Classification of evidence: This study provides Class II evidence that published expert consensus–derived IBM diagnostic categories accurately distinguish IBM from other muscle disease with high specificity but wide-ranging sensitivities. PMID:24975859

Computing and automation division quarterly report, 29 December 1975 - 8 March 1976

International Nuclear Information System (INIS)

Walkinshaw, W.; Lea, A.T.

1976-04-01

The IBM 36/195 has continued much as before under conditions of overall saturation. The recent program of upgrades and additions has been completed. An on-going project of reducing system overheads has gained over 100 CPU hours per quarter for the users. The GEC 4080 system was handed over to Operations Group on 1st January to enter a phase of trial production. (author)