WorldWideScience

Sample records for project links modules

  1. Data transmission optical link for LLRF TESLA project part I: hardware structure of OPT0 module

    Science.gov (United States)

    Pozniak, Krzysztof T.; Romaniuk, Ryszard S.; Jalmuzna, Wojciech; Olowski, Krzysztof; Perkuszewski, Karol; Zielinski, Jerzy; Kierzkowski, Krzysztof

    2006-03-01

    It may be predicted now, even assuming a very conservative approach, that the next generation of the Low Level RF control systems for future accelerators will use extensively such technologies like: very fast programmable circuits equipped with DSP, embedded PC and optical communication I/O functionalities, as well as multi-gigabit optical transmission of measurement data and control signals. The paper presents the idea and realization of a gigabit synchronous data distributor designed to work in the LLRF control system of TESLA technology based X-ray FEL. The design bases on a relatively simple and cheap FPGA chip Cyclone. Commercially available SERDES (serializer/deserializer) and optical transceiver chips were applied. The optoelectronic module is embedded on the main LLRF BMB (backbone mother board). The MB provides communication with the outside computer control system, programmable chip configuration, integration with other functional modules and power supply. The hardware implementation is here described and the used software for BER (bit-error-rate) testing of the multi-gigabit optical link. The measurement results are presented. The appendix contains a comparison between the available protocols of serial data transmission for FPGA technology. This paper is a partial contribution to the next version of the SIMCON system which is expected to be released this year. The SIMCON, ver 3.0 will contain 8 channels and multi-gigabit optical transmission capability. It will be a fully modular construction.

  2. Exploration Augmentation Module Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Exploration Augmentation Module (EAM) project goal is to design and deliver a flight module that is to be deployed to Earth-Lunar Distant Retrograde Orbit (DRO)....

  3. Microprocessor-controlled CAMAC data link module

    International Nuclear Information System (INIS)

    Potter, J.M.

    1978-05-01

    Communication between the central control computer and remote, satellite data-acquisition/control stations at the Clinton P. Anderson Meson Physics Facility (LAMPF) is presently accomplished through the use of CAMAC-based Data Link modules. With the advent of the microprocessor, a new philosophy for digital data communications has evolved. Data Link modules containing microprocessor controllers provide link management and communication network protocol through algorithms executed in the Data Link microprocessor. 13 figures

  4. OCGen Module Mooring Project

    Energy Technology Data Exchange (ETDEWEB)

    McEntee, Jarlath [Ocean Renewable Power Company, LLC, Portland, ME (United States)

    2015-02-06

    Ocean Renewable Power Company's OCGen Module Mooring Project provided an extensive research, design, development, testing and data collection effort and analysis conducted with respect to a positively buoyant, submerged MHK device secured to the seabed using a tensioned mooring system. Different analytic tools were evaluated for their utility in the design of submerged systems and their moorings. Deployment and testing of a prototype OCGen® system provided significant data related to mooring line loads and system attitude and station keeping. Mooring line loads were measured in situ and reported against flow speeds. The Project made a significant step in the development of designs, methodologies and practices related to floating and mooring of marine hydrokinetic (MHK) devices. Importantly for Ocean Renewable Power Company, the Project provided a sound basis for advancing a technically and commercially viable OCGen® Power System. The OCGen® Power System is unique in the MHK industry and, in itself, offers distinct advantages of MHK devices that are secured to the seabed using fixed structural frames. Foremost among these advantages are capital and operating cost reductions and increased power extraction by allowing the device to be placed at the most energetic level of the water column.

  5. Polybinary modulation for bandwidth limited optical links

    DEFF Research Database (Denmark)

    Vegas Olmos, Juan José; Jurado-Navas, Antonio

    2015-01-01

    form of partial response modulation, employs simple codification and filtering at the transmitter to drastically increase the spectral efficiency. At the receiver side, poly binary modulation requires low complexity direct detection and very little digital signal processing. This talk will review...... the recent results on poly binary modulation, comprising both binary and multilevel signals as seed signals. The results will show how poly binary modulation effectively reduces the bandwidth requirements on optical links while providing high spectral efficiency....

  6. The OceanLink Project

    Science.gov (United States)

    Narock, T.; Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Finin, T.; Hitzler, P.; Krisnadhi, A.; Raymond, L. M.; Shepherd, A.; Wiebe, P. H.

    2014-12-01

    A wide spectrum of maturing methods and tools, collectively characterized as the Semantic Web, is helping to vastly improve the dissemination of scientific research. Creating semantic integration requires input from both domain and cyberinfrastructure scientists. OceanLink, an NSF EarthCube Building Block, is demonstrating semantic technologies through the integration of geoscience data repositories, library holdings, conference abstracts, and funded research awards. Meeting project objectives involves applying semantic technologies to support data representation, discovery, sharing and integration. Our semantic cyberinfrastructure components include ontology design patterns, Linked Data collections, semantic provenance, and associated services to enhance data and knowledge discovery, interoperation, and integration. We discuss how these components are integrated, the continued automated and semi-automated creation of semantic metadata, and techniques we have developed to integrate ontologies, link resources, and preserve provenance and attribution.

  7. Bigelow Expandable Activity Module Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Bigelow Expandable Activity Module (BEAM) project is a NASA-industry partnership with Bigelow Aerospace (BA) that has developing the first human-rated expandable...

  8. Projective modules and complete intersections

    CERN Document Server

    Mandal, Satya

    1997-01-01

    In these notes on "Projective Modules and Complete Intersections" an account on the recent developments in research on this subject is presented. The author's preference for the technique of Patching isotopic isomorphisms due to Quillen, formalized by Plumsted, over the techniques of elementary matrices is evident here. The treatment of Basic Element theory here incorporates Plumstead's idea of the "generalized dimension functions". These notes are highly selfcontained and should be accessible to any graduate student in commutative algebra or algebraic geometry. They include fully self-contained presentations of the theorems of Ferrand-Szpiro, Cowsik-Nori and the techniques of Lindel.

  9. Applicability and conception of the 1471 serial link module

    International Nuclear Information System (INIS)

    Weidhase, F.

    1978-01-01

    The 1471 link module developed at the Technical University Dresden is described. The main features are fast data transfer, reliability concerning perturbing effects, seperation of transmitter and receiver self-acting synchronization, completely insulated link modules, high common-mode rejection, self-checking, variable bit repetition frequency, and small demands concerning the transmission cable. Applicabilities are given and a comparison with known link modules is made

  10. The Versatile Link common project: feasibility report

    International Nuclear Information System (INIS)

    Vasey, F; Soos, C; Troska, J; Hall, D; Huffman, T; Weidberg, T; Kwan, S; Prosser, A; Xiang, A; Ye, J

    2012-01-01

    The Versatile Link is a bi-directional digital optical data link operating at rates up to 4.8 Gbit/s and featuring radiation-resistant low-power and low-mass front-end components. The system is being developed in multimode or singlemode versions operating at 850 nm or 1310 nm wavelength respectively. It has serial data interfaces and is protocol-agnostic, but is targeted to operate in tandem with the GigaBit Transceiver (GBT) serializer/deserializer chip being designed at CERN. This paper gives an overview of the project status three and a half years after its launch. It describes the challenges encountered and highlights the solutions proposed at the system as well as the component level. It concludes with a positive feasibility assesment and an outlook for future project development directions.

  11. Health Activities Project (HAP): Breathing Fitness Module.

    Science.gov (United States)

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) learning packet are activities for children in grades 5-8. Design of the activities centers around the idea that students can control their own health and safety. Within this module are teacher and student folios describing four activities which involve students in learning how to measure their…

  12. Detection of deregulated modules using deregulatory linked path.

    Directory of Open Access Journals (Sweden)

    Yuxuan Hu

    Full Text Available The identification of deregulated modules (such as induced by oncogenes is a crucial step for exploring the pathogenic process of complex diseases. Most of the existing methods focus on deregulation of genes rather than the links of the path among them. In this study, we emphasize on the detection of deregulated links, and develop a novel and effective regulatory path-based approach in finding deregulated modules. Observing that a regulatory pathway between two genes might involve in multiple rather than a single path, we identify condition-specific core regulatory path (CCRP to detect the significant deregulation of regulatory links. Using time-series gene expression, we define the regulatory strength within each gene pair based on statistical dependence analysis. The CCRPs in regulatory networks can then be identified using the shortest path algorithm. Finally, we derive the deregulated modules by integrating the differential edges (as deregulated links of the CCRPs between the case and the control group. To demonstrate the effectiveness of our approach, we apply the method to expression data associated with different states of Human Epidermal Growth Factor Receptor 2 (HER2. The experimental results show that the genes as well as the links in the deregulated modules are significantly enriched in multiple KEGG pathways and GO biological processes, most of which can be validated to suffer from impact of this oncogene based on previous studies. Additionally, we find the regulatory mechanism associated with the crucial gene SNAI1 significantly deregulated resulting from the activation of HER2. Hence, our method provides not only a strategy for detecting the deregulated links in regulatory networks, but also a way to identify concerning deregulated modules, thus contributing to the target selection of edgetic drugs.

  13. LINKING PROJECTS TO BUSINESS STRATEGY THROUGH PROJECT PORTFOLIO MANAGEMENT

    Directory of Open Access Journals (Sweden)

    A.J. Buys

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: In many organisations, a chasm exists between the development of strategy and its successful implementation. Failure to cross this chasm may ultimately result in strategy failure and the loss of competitive advantage, profits, and employment. Project Portfolio Management (PPM is theorised as a management methodology that links a portfolio of projects to the business strategy. However, current literature lacks empirical evidence of the levels of employment, functionality, and success of the Project Portfolio Management approach in South Africa. A survey of respondents in 32 technology organisations was used to analyze the reasons for the following: strategy implementation and project delivery failure in South African technology organisations; the South African situation regarding the chasm that exists in many organisations between strategy development and successful strategy implementation; and the extent to which – and with what success – Project Portfolio Management is employed in South African technology organisations.

    AFRIKAANSE OPSOMMING: In baie organisasies bestaan daar ’n gaping tussen strategie-ontwikkeling en suksesvolle strategie-implementering. Die onvermoë om die gaping te oorbrug sal uiteindelik lei tot strategiefaling en die verlies van mededingende voordeel, winste, en werksgeleenthede. Projekportefeuljebestuur (PPB word voorgehou as ’n bestuursmetodologie wat ’n portefeulje van projekte koppel aan die besigheidstrategie. Bestaande literatuur gaan egter mank aan empiriese bewyse ten opsigte van die vlakke van indiensneming, funksionaliteit, en sukses van die Projekportefeuljebestuursbenadering in Suid-Afrika. ’n Opname van respondente in 32 tegnologie-organisasies is gebruik om die volgende aspekte te ondersoek: die redes vir falings in strategie-implementering en projekaflewering in Suid-Afrikaanse tegnologie-organisasies; die Suid-Afrikaanse situasie rakende die gaping wat bestaan tussen

  14. Phase-modulated radio over fiber multimode links.

    Science.gov (United States)

    Gasulla, Ivana; Capmany, José

    2012-05-21

    We present the first experimental demonstration of a phase-modulated MMF link implementing high-frequency digital transmission in a cost-effective solution based on direct detection. Successful subcarrier transmission of QPSK, 16-QAM and 64-QAM data channels for bit rates up to 120 Mb/s through a 5 km MMF link is achieved over the microwave region comprised between 6 and 20 GHz. The overall capacity of the proposed approach can be further increased by properly accommodating more passband channels in the operative frequency range determined by the phase-to-intensity conversion process provided by the dispersive nature of the optical fiber. In this sense, our results show the possibility of achieving an aggregate bit rate per length product of 144 Gb/s · km and confirm, in consequence, the possibility of broadband phase-modulated radio over fiber transmission through MMF links suitable for multichannel SCM signal distribution.

  15. Commutative algebra constructive methods finite projective modules

    CERN Document Server

    Lombardi, Henri

    2015-01-01

    Translated from the popular French edition, this book offers a detailed introduction to various basic concepts, methods, principles, and results of commutative algebra. It takes a constructive viewpoint in commutative algebra and studies algorithmic approaches alongside several abstract classical theories. Indeed, it revisits these traditional topics with a new and simplifying manner, making the subject both accessible and innovative. The algorithmic aspects of such naturally abstract topics as Galois theory, Dedekind rings, Prüfer rings, finitely generated projective modules, dimension theory of commutative rings, and others in the current treatise, are all analysed in the spirit of the great developers of constructive algebra in the nineteenth century. This updated and revised edition contains over 350 well-arranged exercises, together with their helpful hints for solution. A basic knowledge of linear algebra, group theory, elementary number theory as well as the fundamentals of ring and module theory is r...

  16. The Independence Pipeline project : ANR's supply link - Independence Pipeline, Transco's market link

    International Nuclear Information System (INIS)

    Persells, T.

    1998-01-01

    An overview of the Independence Pipeline project was presented. The project offers access from Chicago to the U.S. Midwest market, as well as to Ontario via MichCon, Consumers Power, Great Lakes and Panhandle. The project has three components: ANR's Supply Link, the Independence Pipeline and Transco's MarketLink. The three components are budgeted at $ 1.332 billion dollars and projected for completion between Nov 1999 and Nov 2000. Each component (services, access advantages, market links, rates, storage services, etc ) are described separately. figs

  17. Taiwan links up to world's first LHC computing grid project

    CERN Multimedia

    2003-01-01

    "Taiwan's Academia Sinica was linked up to the Large Hadron Collider (LHC) Computing Grid Project last week to work jointly with 12 other countries to construct the world's largest and most powerful particle accelerator" (1/2 page).

  18. FPGA Based Test Module for Error Bit Evaluation in Serial Links

    Directory of Open Access Journals (Sweden)

    J. Kolouch

    2006-04-01

    Full Text Available A test module for serial links is described. In the link transmitter, one module generates pseudorandom pulse signal that is transmitted by the link. Second module located in the link receiver generates the same signal and compares it to the received signal. Errors caused by the signal transmission can be then detected and results sent to a master computer for further processing like statistical evaluation. The module can be used for long-term error monitoring without need for human operator presence.

  19. Low-cost optical interconnect module for parallel optical data links

    Science.gov (United States)

    Noddings, Chad; Hirsch, Tom J.; Olla, M.; Spooner, C.; Yu, Jason J.

    1995-04-01

    We have designed, fabricated, and tested a prototype parallel ten-channel unidirectional optical data link. When scaled to production, we project that this technology will satisfy the following market penetration requirements: (1) up to 70 meters transmission distance, (2) at least 1 gigabyte/second data rate, and (3) 0.35 to 0.50 MByte/second volume selling price. These goals can be achieved by means of the assembly innovations described in this paper: a novel alignment method that is integrated with low-cost, few chip module packaging techniques, yielding high coupling and reducing the component count. Furthermore, high coupling efficiency increases projected reliability reducing the driver's power requirements.

  20. A Project-Based Biologically-Inspired Robotics Module

    Science.gov (United States)

    Crowder, R. M.; Zauner, K.-P.

    2013-01-01

    The design of any robotic system requires input from engineers from a variety of technical fields. This paper describes a project-based module, "Biologically-Inspired Robotics," that is offered to Electronics and Computer Science students at the University of Southampton, U.K. The overall objective of the module is for student groups to…

  1. The versatile link, a common project for super-LHC

    Energy Technology Data Exchange (ETDEWEB)

    Amaral, Luis; Dris, Stefanos; Gerardin, Alexandre; Huffman, Todd; Issever, Cigdem; Pacheco, Alberto Jimenez; Jones, Mark; Kwan, Simon; Lee, Shih-Chang; Lian, Zhijun; Liu, Tiankuan; /CERN /Oxford U. /Fermilab /Taipei, Computing Ctr. /Southern Methodist U.

    2009-07-01

    Radiation tolerant, high speed optoelectronic data transmission links are fundamental building blocks in today's large scale High Energy Physics (HEP) detectors, as exemplified by the four experiments currently under commissioning at the Large Hadron Collider (LHC), see for example. New experiments or upgrades will impose even more stringent demands on these systems from the point of view of performance and radiation tolerance. This can already be seen from the developments underway for the Super Large Hadron Collider (SLHC) project, a proposed upgrade to the LHC aiming at increasing the luminosity of the machine by factor of 10 to 10{sup 35} cm{sup -2}s{sup -1}, and thus providing a better chance to see rare processes and improving statistically marginal measurements. In the past, specific data transmission links have been independently developed by each LHC experiment for data acquisition (DAQ), detector control as well as trigger and timing distribution (TTC). This was justified by the different types of applications being targeted as well as by technological limitations preventing one single solution from fitting all requirements. However with today's maturity of optoelectronic and CMOS technologies it is possible to envisage the development of a general purpose optical link which can cover most transmission applications: a Versatile Link. Such an approach has the clear advantage of concentrating the development effort on one single project targeting an optical link whose final functionality will only result from the topology and configuration settings adopted.

  2. Down-conversion IM-DD RF photonic link utilizing MQW MZ modulator.

    Science.gov (United States)

    Xu, Longtao; Jin, Shilei; Li, Yifei

    2016-04-18

    We present the first down-conversion intensity modulated-direct detection (IM-DD) RF photonic link that achieves frequency down-conversion using the nonlinear optical phase modulation inside a Mach-Zehnder (MZ) modulator. The nonlinear phase modulation is very sensitive and it can enable high RF-to-IF conversion efficiency. Furthermore, the link linearity is enhanced by canceling the nonlinear distortions from the nonlinear phase modulation and the MZ interferometer. Proof-of-concept measurement was performed. The down-conversion IM-DD link demonstrated 28dB improvement in distortion levels over that of a conventional IM-DD link using a LiNbO3 MZ modulator.

  3. Cognitive digital receiver for burst mode phase modulated radio over fiber links

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Tafur Monroy, Idelfonso

    2010-01-01

    A novel cognitive receiver for modulation format recognition with reconfigurable carrier recovery scheme is proposed and experimentally demonstrated for phase modulated radio-over-fibre links. Demodulation of burst-mode mixed modulation formats (PSK and QAM) is demonstrated after 40km...

  4. Challenges in Polybinary Modulation for Bandwidth Limited Optical Links

    DEFF Research Database (Denmark)

    Vegas Olmos, Juan José; Tafur Monroy, Idelfonso; Madsen, Peter

    2016-01-01

    effectively increase the available capacity. Advanced modulation formats however require digitalization of the signals and digital signal processing blocks to both generate and recover the data. There is therefore a trade-off in terms of efficiency gain vs complexity. Polybinary modulation, a generalized form...

  5. Metric freeness and projectivity for classical and quantum normed modules

    Energy Technology Data Exchange (ETDEWEB)

    Helemskii, A Ya [M. V. Lomonosov Moscow State University, Moscow (Russian Federation)

    2013-07-31

    In functional analysis, there are several diverse approaches to the notion of projective module. We show that a certain general categorical scheme contains all basic versions as special cases. In this scheme, the notion of free object comes to the foreground, and, in the best categories, projective objects are precisely retracts of free ones. We are especially interested in the so-called metric version of projectivity and characterize the metrically free classical and quantum (= operator) normed modules. Informally speaking, so-called extremal projectivity, which was known earlier, is interpreted as a kind of 'asymptotical metric projectivity'. In addition, we answer the following specific question in the geometry of normed spaces: what is the structure of metrically projective modules in the simplest case of normed spaces? We prove that metrically projective normed spaces are precisely the subspaces of l{sub 1}(M) (where M is a set) that are denoted by l{sub 1}{sup 0}(M) and consist of finitely supported functions. Thus, in this case, projectivity coincides with freeness. Bibliography: 28 titles.

  6. Provenance Usage in the OceanLink Project

    Science.gov (United States)

    Narock, T.; Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Fils, D.; Finin, T.; Hitzler, P.; Janowicz, K.; Jones, M.; Krisnadhi, A.; Lehnert, K. A.; Mickle, A.; Raymond, L. M.; Schildhauer, M.; Shepherd, A.; Wiebe, P. H.

    2014-12-01

    A wide spectrum of maturing methods and tools, collectively characterized as the Semantic Web, is helping to vastly improve thedissemination of scientific research. The OceanLink project, an NSF EarthCube Building Block, is utilizing semantic technologies tointegrate geoscience data repositories, library holdings, conference abstracts, and funded research awards. Provenance is a vital componentin meeting both the scientific and engineering requirements of OceanLink. Provenance plays a key role in justification and understanding when presenting users with results aggregated from multiple sources. In the engineering sense, provenance enables the identification of new data and the ability to determine which data sources to query. Additionally, OceanLink will leverage human and machine computation for crowdsourcing, text mining, and co-reference resolution. The results of these computations, and their associated provenance, will be folded back into the constituent systems to continually enhance precision and utility. We will touch on the various roles provenance is playing in OceanLink as well as present our use of the PROV Ontology and associated Ontology Design Patterns.

  7. 225m Outdoor W-Band Radio-over-Fiber Link Using an Optical SFP+ Module

    DEFF Research Database (Denmark)

    Rommel, Simon; Rodríguez Páez, Juan Sebastián; Chorchos, Łukasz

    2016-01-01

    A W-band radio-over-fiber link based on a commercial SFP+ module is demonstrated, allowing easy integration into existing PON solutions. Without active laser control good RF frequency stability and 225m wireless distance are achieved...

  8. Direct modulation and detection link using polybinary signaling

    DEFF Research Database (Denmark)

    Suhr, L.F.; Vegas Olmos, Juan José; Peucheret, Christophe

    2014-01-01

    This paper presents experimental results on a spectral efficient optical fiber link by using a novel seven-level polybinary signaling at 14.32 Gbps achieving a potential 7.95 b/s/Hz with very little complexity and processing footprint.......This paper presents experimental results on a spectral efficient optical fiber link by using a novel seven-level polybinary signaling at 14.32 Gbps achieving a potential 7.95 b/s/Hz with very little complexity and processing footprint....

  9. A novel modulation scheme for noise reduction in analog fiber optic links

    NARCIS (Netherlands)

    Marpaung, D.A.I.; Roeloffzen, C.G.H.; van Etten, Wim

    2006-01-01

    A novel noise reduction scheme called Balanced Modulation and Detection (BMD) is proposed. In this scheme, the modulating RF signal is half-wave rectified in the optical domain, eliminating the DC optical power resulting from pre-biasing of the optical source. A link model employing this scheme has

  10. A novel modulation scheme for noise reduction in analog fiber optic links

    NARCIS (Netherlands)

    Marpaung, D.A.I.; Roeloffzen, C.G.H.; van Etten, Wim; Megret, P.; Wuilpart, M.; Bette, S.; Staquet, N.

    2005-01-01

    A novel balanced modulation and detection scheme for analog fiber optic links is proposed to overcome the limitations in signal-to-noise ratio (SNR) and dynamic range (DR).In this scheme, the modulating signal is split into positive and negative halves and applied to a pair of laser diodes. Both

  11. Health Activities Project (HAP): Sight and Sound Module.

    Science.gov (United States)

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) learning packet are activities for children in grades 5-8. Design of the activities centers around the idea that students can control their own health and safety. Within this module are teacher and student folios describing six activities which involve students in restricting their vision by…

  12. Health Activities Project (HAP): Action/Reaction Module.

    Science.gov (United States)

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) learning packet are activities for children in grades 5-8. Design of the activities centers around the idea that students can control their own health and safety. Within this module are teacher and student folios describing activities in timing, improving, and practicing to improve reaction…

  13. Health Activities Project (HAP): Heart Fitness and Action Module.

    Science.gov (United States)

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) learning packet are activities for children in grades 5-8. Design of the activities centers around the idea that students can control their own health and safety. Within the Heart Fitness and Action Module are teacher and student folios describing five activities which involve students in…

  14. Electrically modulated transparent liquid crystal-optical grating projection

    DEFF Research Database (Denmark)

    Buss, Thomas; Smith, Cameron; Kristensen, Anders

    2013-01-01

    A transparent, fully integrated electrically modulated projection technique is presented based on light guiding through a thin liquid crystal layer covering sub-wavelength gratings. The reported device operates at 10 V with response times of 4.5 ms. Analysis of the liquid crystal alignment shows...

  15. Ring resonator-based on-chip modulation transformer for high-performance phase-modulated microwave photonic links.

    Science.gov (United States)

    Zhuang, Leimeng; Taddei, Caterina; Hoekman, Marcel; Leinse, Arne; Heideman, René; van Dijk, Paulus; Roeloffzen, Chris

    2013-11-04

    In this paper, we propose and experimentally demonstrate a novel wideband on-chip photonic modulation transformer for phase-modulated microwave photonic links. The proposed device is able to transform phase-modulated optical signals into intensity-modulated versions (or vice versa) with nearly zero conversion of laser phase noise to intensity noise. It is constructed using waveguide-based ring resonators, which features simple architecture, stable operation, and easy reconfigurability. Beyond the stand-alone functionality, the proposed device can also be integrated with other functional building blocks of photonic integrated circuits (PICs) to create on-chip complex microwave photonic signal processors. As an application example, a PIC consisting of two such modulation transformers and a notch filter has been designed and realized in TriPleX(TM) waveguide technology. The realized device uses a 2 × 2 splitting circuit and 3 ring resonators with a free spectral range of 25 GHz, which are all equipped with continuous tuning elements. The device can perform phase-to-intensity modulation transform and carrier suppression simultaneously, which enables high-performance phase-modulated microwave photonics links (PM-MPLs). Associated with the bias-free and low-complexity advantages of the phase modulators, a single-fiber-span PM-MPL with a RF bandwidth of 12 GHz (3 dB-suppression band 6 to 18 GHz) has been demonstrated comprising the proposed PIC, where the achieved spurious-free dynamic range performance is comparable to that of Class-AB MPLs using low-biased Mach-Zehnder modulators.

  16. The advanced linked extended reconnaissance and targeting technology demonstration project

    Science.gov (United States)

    Cruickshank, James; de Villers, Yves; Maheux, Jean; Edwards, Mark; Gains, David; Rea, Terry; Banbury, Simon; Gauthier, Michelle

    2007-06-01

    The Advanced Linked Extended Reconnaissance & Targeting (ALERT) Technology Demonstration (TD) project is addressing key operational needs of the future Canadian Army's Surveillance and Reconnaissance forces by fusing multi-sensor and tactical data, developing automated processes, and integrating beyond line-of-sight sensing. We discuss concepts for displaying and fusing multi-sensor and tactical data within an Enhanced Operator Control Station (EOCS). The sensor data can originate from the Coyote's own visible-band and IR cameras, laser rangefinder, and ground-surveillance radar, as well as beyond line-of-sight systems such as a mini-UAV and unattended ground sensors. The authors address technical issues associated with the use of fully digital IR and day video cameras and discuss video-rate image processing developed to assist the operator to recognize poorly visible targets. Automatic target detection and recognition algorithms processing both IR and visible-band images have been investigated to draw the operator's attention to possible targets. The machine generated information display requirements are presented with the human factors engineering aspects of the user interface in this complex environment, with a view to establishing user trust in the automation. The paper concludes with a summary of achievements to date and steps to project completion.

  17. Impact of modulation bandwidth on multiplexing using principal modes in MMF links.

    Science.gov (United States)

    Prasad, Rohan; Appaiah, Kumar

    2018-01-22

    Multimode fibers (MMFs) are widely used for short fiber links. However, the data rates through MMFs is limited owing to modal dispersion. The so-called "principal modes" (PMs) permit transmission and multiplexing through the MMFs without modal dispersion for small modulation bandwidths. For larger modulation bandwidths, however, they lose their dispersion-free nature. In this paper, we model the impact of modulation bandwidth and mode coupling strength on the performance of PMs. We develop a simulator that characterizes the dispersion and cross-talk of the PMs of few-mode and large-core graded-index MMFs with mode-dependent losses (MDL). Simulations reveal that for fibers without MDL, for modulation frequencies beyond 10 GHz diminishes the PMs' frequency response by more than 1 dB for 100 m in large-core MMF links and 10 km few-mode fiber links. With MDL, simulations reveal that for modulation bandwidths beyond 2 GHz diminishes the frequency response by 3 dB for a 1 km few-mode fiber and by more than 4 dB for a 1 km large-core multimode fiber. While multiplexing using PMs in large-core MMFs with MDL, we find that for modulation bandwidths beyond 3 GHz, the cross-talk is 20 dB in 1 km large-core MMF links, thereby limiting system performance.

  18. The Advanced Linked Extended Reconnaissance & Targeting Technology Demonstration project

    Science.gov (United States)

    Edwards, Mark

    2008-04-01

    The Advanced Linked Extended Reconnaissance & Targeting (ALERT) Technology Demonstration (TD) project is addressing many operational needs of the future Canadian Army's Surveillance and Reconnaissance forces. Using the surveillance system of the Coyote reconnaissance vehicle as an experimental platform, the ALERT TD project aims to significantly enhance situational awareness by fusing multi-sensor and tactical data, developing automated processes, and integrating beyond line-of-sight sensing. The project is exploiting important advances made in computer processing capability, displays technology, digital communications, and sensor technology since the design of the original surveillance system. As the major research area within the project, concepts are discussed for displaying and fusing multi-sensor and tactical data within an Enhanced Operator Control Station (EOCS). The sensor data can originate from the Coyote's own visible-band and IR cameras, laser rangefinder, and ground-surveillance radar, as well as from beyond line-of-sight systems such as mini-UAVs and unattended ground sensors. Video-rate image processing has been developed to assist the operator to detect poorly visible targets. As a second major area of research, automatic target cueing capabilities have been added to the system. These include scene change detection, automatic target detection and aided target recognition algorithms processing both IR and visible-band images to draw the operator's attention to possible targets. The merits of incorporating scene change detection algorithms are also discussed. In the area of multi-sensor data fusion, up to Joint Defence Labs level 2 has been demonstrated. The human factors engineering aspects of the user interface in this complex environment are presented, drawing upon multiple user group sessions with military surveillance system operators. The paper concludes with Lessons Learned from the project. The ALERT system has been used in a number of C4ISR

  19. Flat-plate solar array project. Volume 7: Module encapsulation

    Science.gov (United States)

    Cuddihy, E.; Coulbert, C.; Gupta, A.; Liang, R.

    1986-01-01

    The objective of the Encapsulation Task was to develop, demonstrate, and qualify photovoltaic (PV) module encapsulation systems that would provide 20 year (later decreased to 30 year) life expectancies in terrestrial environments, and which would be compatible with the cost and performance goals of the Flat-Plate Solar Array (FSA) Project. The scope of the Encapsulation Task included the identification, development, and evaluation of material systems and configurations required to support and protect the optically and electrically active solar cell circuit components in the PV module operating environment. Encapsulation material technologies summarized include the development of low cost ultraviolet protection techniques, stable low cost pottants, soiling resistant coatings, electrical isolation criteria, processes for optimum interface bonding, and analytical and experimental tools for evaluating the long term durability and structural adequacy of encapsulated modules. Field testing, accelerated stress testing, and design studies have demonstrated that encapsulation materials, processes, and configurations are available that meet the FSA cost and performance goals.

  20. Recombination Modulates How Selection Affects Linked Sites in Drosophila

    Science.gov (United States)

    McGaugh, Suzanne E.; Heil, Caiti S. S.; Manzano-Winkler, Brenda; Loewe, Laurence; Goldstein, Steve; Himmel, Tiffany L.; Noor, Mohamed A. F.

    2012-01-01

    One of the most influential observations in molecular evolution has been a strong association between local recombination rate and nucleotide polymorphisms across the genome. This is interpreted as evidence for ubiquitous natural selection. The alternative explanation, that recombination is mutagenic, has been rejected by the absence of a similar association between local recombination rate and nucleotide divergence between species. However, many recent studies show that recombination rates are often very different even in closely related species, questioning whether an association between recombination rate and divergence between species has been tested satisfactorily. To circumvent this problem, we directly surveyed recombination across approximately 43% of the D. pseudoobscura physical genome in two separate recombination maps and 31% of the D. miranda physical genome, and we identified both global and local differences in recombination rate between these two closely related species. Using only regions with conserved recombination rates between and within species and accounting for multiple covariates, our data support the conclusion that recombination is positively related to diversity because recombination modulates Hill–Robertson effects in the genome and not because recombination is predominately mutagenic. Finally, we find evidence for dips in diversity around nonsynonymous substitutions. We infer that at least some of this reduction in diversity resulted from selective sweeps and examine these dips in the context of recombination rate. PMID:23152720

  1. Coding/modulation trade-offs for Shuttle wideband data links

    Science.gov (United States)

    Batson, B. H.; Huth, G. K.; Trumpis, B. D.

    1974-01-01

    This paper describes various modulation and coding schemes which are potentially applicable to the Shuttle wideband data relay communications link. This link will be capable of accommodating up to 50 Mbps of scientific data and will be subject to a power constraint which forces the use of channel coding. Although convolutionally encoded coherent binary PSK is the tentative signal design choice for the wideband data relay link, FM techniques are of interest because of the associated hardware simplicity and because an FM system is already planned to be available for transmission of television via relay satellite to the ground. Binary and M-ary FSK are considered as candidate modulation techniques, and both coherent and noncoherent ground station detection schemes are examined. The potential use of convolutional coding is considered in conjunction with each of the candidate modulation techniques.

  2. A method for identifying hierarchical sub-networks / modules and weighting network links based on their similarity in sub-network / module affiliation

    Directory of Open Access Journals (Sweden)

    WenJun Zhang

    2016-06-01

    Full Text Available Some networks, including biological networks, consist of hierarchical sub-networks / modules. Based on my previous study, in present study a method for both identifying hierarchical sub-networks / modules and weighting network links is proposed. It is based on the cluster analysis in which between-node similarity in sets of adjacency nodes is used. Two matrices, linkWeightMat and linkClusterIDs, are achieved by using the algorithm. Two links with both the same weight in linkWeightMat and the same cluster ID in linkClusterIDs belong to the same sub-network / module. Two links with the same weight in linkWeightMat but different cluster IDs in linkClusterIDs belong to two sub-networks / modules at the same hirarchical level. However, a link with an unique cluster ID in linkClusterIDs does not belong to any sub-networks / modules. A sub-network / module of the greater weight is the more connected sub-network / modules. Matlab codes of the algorithm are presented.

  3. A Multi-Cycle Q-Modulation for Dynamic Optimization of Inductive Links.

    Science.gov (United States)

    Lee, Byunghun; Yeon, Pyungwoo; Ghovanloo, Maysam

    2016-08-01

    This paper presents a new method, called multi-cycle Q-modulation, which can be used in wireless power transmission (WPT) to modulate the quality factor (Q) of the receiver (Rx) coil and dynamically optimize the load impedance to maximize the power transfer efficiency (PTE) in two-coil links. A key advantage of the proposed method is that it can be easily implemented using off-the-shelf components without requiring fast switching at or above the carrier frequency, which is more suitable for integrated circuit design. Moreover, the proposed technique does not need any sophisticated synchronization between the power carrier and Q-modulation switching pulses. The multi-cycle Q-modulation is analyzed theoretically by a lumped circuit model, and verified in simulation and measurement using an off-the-shelf prototype. Automatic resonance tuning (ART) in the Rx, combined with multi-cycle Q-modulation helped maximizing PTE of the inductive link dynamically in the presence of environmental and loading variations, which can otherwise significantly degrade the PTE in multi-coil settings. In the prototype conventional 2-coil link, the proposed method increased the power amplifier (PA) plus inductive link efficiency from 4.8% to 16.5% at ( R L = 1 kΩ, d 23 = 3 cm), and from 23% to 28.2% at ( R L = 100 Ω, d 23 = 3 cm) after 11% change in the resonance capacitance, while delivering 168.1 mW to the load (PDL).

  4. The link between the use of advanced planning and scheduling (APS) modules and factory context

    DEFF Research Database (Denmark)

    Kristensen, Jesper; Asmussen, Jesper Normann; Wæhrens, Brian Vejrum

    2017-01-01

    at factories characterized by low planning maturity, but lower for factories with medium planning maturity. For low planning maturity, the APS module is used for improving the configuration of the manufacturing system, whereas high planning maturity is required to capture performance benefits from optimization......Through a study of four embedded action research cases within a global OEM, it is investigated how the frequency of use and contribution of an Advanced Planning and Scheduling (APS) module are affected by factory context. The performance contribution of the APS module is found to be high...... and scenario planning. Further, it is found that planning complexity at the factory increases both the frequency of use and the contribution of using APS modules. On the basis of the findings, three propositions are formulated on the link between factory context and the use of APS module....

  5. Project management plan, Waste Receiving and Processing Facility, Module 1, Project W-026

    Energy Technology Data Exchange (ETDEWEB)

    Starkey, J.G.

    1993-05-01

    The Hanford Waste Receiving and Processing Facility Module 1 Project (WRAP 1) has been established to support the retrieval and final disposal of approximately 400K grams of plutonium and quantities of hazardous components currently stored in drums at the Hanford Site.

  6. Project management plan, Waste Receiving and Processing Facility, Module 1, Project W-026

    International Nuclear Information System (INIS)

    Starkey, J.G.

    1993-05-01

    The Hanford Waste Receiving and Processing Facility Module 1 Project (WRAP 1) has been established to support the retrieval and final disposal of approximately 400K grams of plutonium and quantities of hazardous components currently stored in drums at the Hanford Site

  7. Frequency position modulation using multi-spectral projections

    Science.gov (United States)

    Goodman, Joel; Bertoncini, Crystal; Moore, Michael; Nousain, Bryan; Cowart, Gregory

    2012-10-01

    In this paper we present an approach to harness multi-spectral projections (MSPs) to carefully shape and locate tones in the spectrum, enabling a new and robust modulation in which a signal's discrete frequency support is used to represent symbols. This method, called Frequency Position Modulation (FPM), is an innovative extension to MT-FSK and OFDM and can be non-uniformly spread over many GHz of instantaneous bandwidth (IBW), resulting in a communications system that is difficult to intercept and jam. The FPM symbols are recovered using adaptive projections that in part employ an analog polynomial nonlinearity paired with an analog-to-digital converter (ADC) sampling at a rate at that is only a fraction of the IBW of the signal. MSPs also facilitate using commercial of-the-shelf (COTS) ADCs with uniform-sampling, standing in sharp contrast to random linear projections by random sampling, which requires a full Nyquist rate sample-and-hold. Our novel communication system concept provides an order of magnitude improvement in processing gain over conventional LPI/LPD communications (e.g., FH- or DS-CDMA) and facilitates the ability to operate in interference laden environments where conventional compressed sensing receivers would fail. We quantitatively analyze the bit error rate (BER) and processing gain (PG) for a maximum likelihood based FPM demodulator and demonstrate its performance in interference laden conditions.

  8. Performance Evaluation of Digital Coherent Receivers for Phase-Modulated Radio-Over-Fiber Links

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Zibar, Darko; Tafur Monroy, Idelfonso

    2011-01-01

    The performance of optical phase-modulated (PM) radio-over-fiber (RoF) links assisted with coherent detection and digital signal processing (PM-Coh) is analyzed and experimentally demonstrated for next-generation wireless-over-fiber systems. PM-Coh offers high linearity for transparent transport ...

  9. Multiband Carrierless Amplitude Phase Modulation for High Capacity Optical Data Links

    DEFF Research Database (Denmark)

    Iglesias Olmedo, Miguel; Zuo, Tianjian; Jensen, Jesper Bevensee

    2014-01-01

    . The reported experiment uses MultiCAP to achieve 102.4 Gb/s transmission, corresponding to a data payload of 95.2 Gb/s error free transmission by using a 7% forward error correction (FEC) code. The signal is successfully recovered after 15 km of standard single mode fiber (SSMF) in a system limited by a 3 d......Short range optical data links are experiencing bandwidth limitations making it very challenging to cope with the growing data transmission capacity demands. Parallel optics appears as a valid short-term solution. It is, however, not a viable solution in the long-term because of its complex optical...... packaging. Therefore, increasing effort is now put into the possibility of exploiting higher order modulation formats with increased spectral efficiency and reduced optical transceiver complexity. As these type of links are based on intensity modulation and direct detection, modulation formats relying...

  10. A voltage control method for an active capacitive DC-link module with series-connected circuit

    DEFF Research Database (Denmark)

    Wang, Haoran; Wang, Huai; Blaabjerg, Frede

    2017-01-01

    Many efforts have been made to improve the performance of power electronic systems with active capacitive DC-link module in terms of power density as well as reliability. One of the attractive solution is an active capacitive DC-link with the series-connected circuit because of handling small......-rated power. However, in the existing control method of this circuit, the DC-link current of the backward-stage or forward-stage need to be sensed for extracting the ripple components, which limits the flexibility of the active DC-link module. Thus, in this paper, a voltage control method of an active...... capacitive DC-link module is proposed. Current sensor at the DC-link will be cancel from the circuit. The controller of the series-connected circuit requires internal voltage signals of the DC-link module only, making it possible to be fully independent without any additional connection to the main circuit...

  11. Second quantization, projective modules, and local gauge invariance

    Energy Technology Data Exchange (ETDEWEB)

    Selesnick, S A [Missouri Univ., St. Louis (USA)

    1983-01-01

    Bundles and bundle structures have gained wide currency in modern approaches to certain topics in quantum physics, significant applications appearing in connection with gauge theories, theories of geometric quantization, and in numerous other contexts. It is argued that such structures can already be discerned in the most elementary notions of second quantization. An examination of the methods traditionally used by physicists in dealing quantum mechanically with systems exhibiting an infinite number of degrees of freedom reveals the implicit use of module structures over algebras of functions. By making these structures explicit and adapting some results of perturbation theory an association between bare particles and finitely generated projective modules is arrived at. In particular, rank one modules emerge naturally, for algebraic reasons, as the appropriate descriptors of bosons in this association. As a first application of the formalism the existence of phononlike excitations in general many-fermion systems is shown. When these ideas are further specialized (local) gauge theoretical notions arise in a natural way out of a consideration of the bundles.

  12. Electrical power inverter having a phase modulated, twin-inverter, high frequency link and an energy storage module

    Science.gov (United States)

    Pitel, Ira J.

    1987-02-03

    The present invention provides an electrical power inverter method and apparatus, which includes a high frequency link, for converting DC power into AC power. Generally stated, the apparatus includes a first high frequency module which produces an AC voltage at a first output frequency, and a second high frequency inverter module which produces an AC voltage at a second output frequency that is substantially the same as the first output frequency. The second AC voltage is out of phase with the first AC voltage by a selected angular phase displacement. A mixer mixes the first and second output voltages to produce a high frequency carrier which has a selected base frequency impressed on the sidebands thereof. A rectifier rectifies the carrier, and a filter filters the rectified carrier. An output inverter inverts the filtered carrier to produce an AC line voltage at the selected base frequency. A phase modulator adjusts the relative angular phase displacement between the outputs of the first and second high frequency modules to control the base frequency and magnitude of the AC line voltage.

  13. Electrical power inverter having a phase modulated, twin-inverter, high frequency link and an energy storage module

    Science.gov (United States)

    Pitel, I.J.

    1987-02-03

    The present invention provides an electrical power inverter method and apparatus, which includes a high frequency link, for converting DC power into AC power. Generally stated, the apparatus includes a first high frequency module which produces an AC voltage at a first output frequency, and a second high frequency inverter module which produces an AC voltage at a second output frequency that is substantially the same as the first output frequency. The second AC voltage is out of phase with the first AC voltage by a selected angular phase displacement. A mixer mixes the first and second output voltages to produce a high frequency carrier which has a selected base frequency impressed on the sidebands thereof. A rectifier rectifies the carrier, and a filter filters the rectified carrier. An output inverter inverts the filtered carrier to produce an AC line voltage at the selected base frequency. A phase modulator adjusts the relative angular phase displacement between the outputs of the first and second high frequency modules to control the base frequency and magnitude of the AC line voltage. 19 figs.

  14. Sub-cycle QAM modulation for VCSEL-based optical fiber links

    DEFF Research Database (Denmark)

    Pham, Tien-Thang; Rodes Lopez, Roberto; Jensen, Jesper Bevensee

    2013-01-01

    QAM modulation utilizing subcarrier frequency lower than the symbol rate is both theoretically and experimentally investigated. High spectral efficiency and concentration of power in low frequencies make sub-cycle QAM signals attractive for optical fiber links with direct modulated light sources....... Real-time generated 10-Gbps 4-level QAM signal in a 7.5-GHz bandwidth utilizing subcarrier frequency at a half symbol rate was successfully transmitted over 20-km SMF using an un-cooled 1.5-μm VCSEL. Only 2.5-dB fiber transmission power penalty was observed with no equalization applied....

  15. Comparison of PAM and CAP modulations robustness against mode partition noise in optical links

    Science.gov (United States)

    Stepniak, Grzegorz

    2017-08-01

    Mode partition noise (MPN) of the laser employed at the transmitter can significantly degrade the transmission performance. In the paper, we introduce a simulation model of MPN in vertical cavity surface emitting laser (VCSEL) and simulate transmission of pulse amplitude modulation (PAM) and carrierless amplitude phase (CAP) signals in multimode fiber (MMF) link. By turning off other effects, like relative intensity noise (RIN), we focus solely on the influence of MPN on transmission performance degradation. Robustness of modulation and equalization type against MPN is studied.

  16. Investigations of Polarization Dependent Loss in Polarization Modulated Analog Optical Links

    Science.gov (United States)

    2015-12-29

    performance analog optical links for military applications primarily rely on the most common link architecture employing intensity modulation with...axis as bisector of DD and Ss•) PP = fl i p ( rr, PPO] ; (• flip the P vector imaqe on the PA •) PPh a t = unit[PP ) ; PHI = ArcCos [ PPha t .unit...DD ) ); AA = ((Cos ( PHI / 2])𔃼 • t p (Sin [ PHI / 2 ])𔃼 ) PP • tpDDhat / 2 ; CC2 =- ( MM · AA . SS • (AA . I!M) (I!M. SS)) ; CC3 = AA . SS; ln

  17. Long Lifetime DC-Link Voltage Stabilization Module for Smart Grid Application

    DEFF Research Database (Denmark)

    Wang, Huai; Chung, Henry; Liu, Wenchao

    2012-01-01

    Power converters enable efficient and flexible control and conversion of electric energy among different smart grid players (i.e. producers, energy storage systems, and loads). One of the expected features of smart grid is that it will be more reliable compared to conventional grid. However, power...... converters are one kind of the lifetime limiting components applied in smart grid. One of the major causes is the malfunction of electrolytic capacitors (E-Caps) which are widely used for stabilizing the dc-link voltage in various types of power converters applied in smart grid. A dc-link module is therefore...

  18. Linked open data creating knowledge out of interlinked data : results of the LOD2 project

    CERN Document Server

    Bryl, Volha; Tramp, Sebastian

    2014-01-01

    Linked Open Data (LOD) is a pragmatic approach for realizing the Semantic Web vision of making the Web a global, distributed, semantics-based information system. This book presents an overview on the results of the research project “LOD2 -- Creating Knowledge out of Interlinked Data”. LOD2 is a large-scale integrating project co-funded by the European Commission within the FP7 Information and Communication Technologies Work Program. Commencing in September 2010, this 4-year project comprised leading Linked Open Data research groups, companies, and service providers from across 11 European countries and South Korea. The aim of this project was to advance the state-of-the-art in research and development in four key areas relevant for Linked Data, namely 1. RDF data management; 2. the extraction, creation, and enrichment of structured RDF data; 3. the interlinking and fusion of Linked Data from different sources and 4. the authoring, exploration and visualization of Linked Data.

  19. Hydrostatic Pressure Project: Linked-Class Problem-Based Learning in Engineering

    Science.gov (United States)

    Davis, Freddie J.; Lockwood-Cooke, Pamela; Hunt, Emily M.

    2011-01-01

    Over the last few years, WTAMU Mathematics, Engineering and Science faculty has used interdisciplinary projects as the basis for implementation of a linked-class approach to Problem-Based Learning (PBL). A project that has significant relevance to engineering statics, fluid mechanics, and calculus is the Hydrostatic Pressure Project. This project…

  20. On the left perpendicular category of the modules of finite projective dimension

    OpenAIRE

    Araya, Tokuji; Iima, Kei-ichiro; Takahashi, Ryo

    2010-01-01

    In this paper, we characterize several properties of commutative notherian local rings in terms of the left perpendicular category of the category of finitely generated modules of finite projective dimension. As an application we prove that a local ring is regular if (and only if) there exists a strong test module for projectivity having finite projective dimension. We also obtain corresponding results with respect to a semidualizing module.

  1. A DC-Link Modulation Scheme with Phase-Shifted Current Control for Harmonic Cancellations in Multidrive Applications

    DEFF Research Database (Denmark)

    Yang, Yongheng; Davari, Pooya; Zare, Firuz

    2016-01-01

    of a new DC link modulation scheme with a phase-shifted current control enabled by the SCR. The DC-link current modulation scheme is implemented by adding and subtracting specific modulation levels, which makes the total currents drawn from the grid “multi-level”, resulting in an improved current quality......This letter proposes a harmonic mitigation strategy to cancel out current harmonics induced by the front-end rectifiers in multi-drive systems, which consist of diode rectifiers, Silicon-Controlled Rectifiers (SCR), and boost converters in the DC-link. The proposed strategy is a combination...

  2. Linking Multiple Databases: Term Project Using "Sentences" DBMS.

    Science.gov (United States)

    King, Ronald S.; Rainwater, Stephen B.

    This paper describes a methodology for use in teaching an introductory Database Management System (DBMS) course. Students master basic database concepts through the use of a multiple component project implemented in both relational and associative data models. The associative data model is a new approach for designing multi-user, Web-enabled…

  3. Basal forebrain projections to the lateral habenula modulate aggression reward.

    Science.gov (United States)

    Golden, Sam A; Heshmati, Mitra; Flanigan, Meghan; Christoffel, Daniel J; Guise, Kevin; Pfau, Madeline L; Aleyasin, Hossein; Menard, Caroline; Zhang, Hongxing; Hodes, Georgia E; Bregman, Dana; Khibnik, Lena; Tai, Jonathan; Rebusi, Nicole; Krawitz, Brian; Chaudhury, Dipesh; Walsh, Jessica J; Han, Ming-Hu; Shapiro, Matt L; Russo, Scott J

    2016-06-30

    Maladaptive aggressive behaviour is associated with a number of neuropsychiatric disorders and is thought to result partly from the inappropriate activation of brain reward systems in response to aggressive or violent social stimuli. Nuclei within the ventromedial hypothalamus, extended amygdala and limbic circuits are known to encode initiation of aggression; however, little is known about the neural mechanisms that directly modulate the motivational component of aggressive behaviour. Here we established a mouse model to measure the valence of aggressive inter-male social interaction with a smaller subordinate intruder as reinforcement for the development of conditioned place preference (CPP). Aggressors develop a CPP, whereas non-aggressors develop a conditioned place aversion to the intruder-paired context. Furthermore, we identify a functional GABAergic projection from the basal forebrain (BF) to the lateral habenula (lHb) that bi-directionally controls the valence of aggressive interactions. Circuit-specific silencing of GABAergic BF-lHb terminals of aggressors with halorhodopsin (NpHR3.0) increases lHb neuronal firing and abolishes CPP to the intruder-paired context. Activation of GABAergic BF-lHb terminals of non-aggressors with channelrhodopsin (ChR2) decreases lHb neuronal firing and promotes CPP to the intruder-paired context. Finally, we show that altering inhibitory transmission at BF-lHb terminals does not control the initiation of aggressive behaviour. These results demonstrate that the BF-lHb circuit has a critical role in regulating the valence of inter-male aggressive behaviour and provide novel mechanistic insight into the neural circuits modulating aggression reward processing.

  4. Antisocial behaviour and psychopathy: Uncovering the externalizing link in the P3 modulation.

    Science.gov (United States)

    Pasion, Rita; Fernandes, Carina; Pereira, Mariana R; Barbosa, Fernando

    2017-03-22

    In 2009, Gao and Raine's meta-analysis analysed P3 modulation over the antisocial spectrum. However, some questions remained open regarding the P3 modulation patterns across impulsive and violent manifestations of antisocial behaviour, phenotypic components of psychopathy, and P3 components. A systematic review of 36 studies was conducted (N=3514) to extend previous results and to address these unresolved questions. A clear link between decreased P3 amplitude and antisocial behaviour was found. In psychopathy, dimensional approaches become more informative than taxonomic models. Distinct etiological pathways of psychopathy were evidenced in cognitive tasks: impulsive-antisocial psychopathic traits mainly predicted blunted P3 amplitude, while interpersonal-affective psychopathic traits explained enhanced P3 amplitude. Supporting the low fear hypothesis, the interpersonal-affective traits were associated with reduced P3 amplitude in emotional-affective learning tasks. From the accumulated knowledge we propose a framework of P3 amplitude modulation that uncovers the externalizing link between psychopathy and antisocial behaviour. However, the main hypotheses are exploratory and call for more data before stablishing robust conclusions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Taiwan links up to world's 1st LHC Computing Grid Project

    CERN Multimedia

    2003-01-01

    Taiwan's Academia Sinica was linked up to the Large Hadron Collider (LHC) Computing Grid Project to work jointly with 12 other countries to construct the world's largest and most powerful particle accelerator

  6. Free-Space Optical Communications Link at 1550-nm using Multiple-Quantum-Well Modulating Retroreflectors in a Marine Environment

    National Research Council Canada - National Science Library

    Rabinovich, W. S; Mahon, R; Burris, H. R; Gilbreath, G. C; Goetz, P. G; Moore, C. I; Stell, M. F; Vilcheck, M. J; Witkowsky, J. L; Swingen, L

    2005-01-01

    A 1550-nm eye-safe, free-space optical communications link is demonstrated at rates up to 5 Mbits/s over a distance of 2 km in the Chesapeake Bay, using quantum-well-based modulating retroreflectors...

  7. Laser Noise and its Impact on the Performance of Intensity-Modulation with Direct-Detection Analog Photonic Links

    National Research Council Canada - National Science Library

    Urick, Vincent J; Devgan, Preetpaul S; McKinney, Jason D; Dexter, James L

    2007-01-01

    The equations for radio-frequency gain, radio-frequency noise figure, compression dynamic range and spurious-free dynamic range are derived for an analog photonic link employing intensity modulation and direct detection...

  8. A homomorphism between link and XXZ modules over the periodic Temperley–Lieb algebra

    International Nuclear Information System (INIS)

    Morin-Duchesne, Alexi; Saint-Aubin, Yvan

    2013-01-01

    We study finite loop models on a lattice wrapped around a cylinder. A section of the cylinder has N sites. We use a family of link modules over the periodic Temperley–Lieb algebra EPTL N (β,α) introduced by Martin and Saleur, and Graham and Lehrer. These are labeled by the numbers of sites N and of defects d, and extend the standard modules of the original Temperley–Lieb algebra. Besides the defining parameters β = u 2 + u −2 with u = e iλ/2 (weight of contractible loops) and α (weight of non-contractible loops), this family also depends on a twist parameter v that keeps track of how the defects wind around the cylinder. The transfer matrix T N (λ, ν) depends on the anisotropy ν and the spectral parameter λ that fixes the model. (The thermodynamic limit of T N is believed to describe conformal field theory of central charge c = 1 − 6λ 2 /(π(λ − π)).) The family of periodic XXZ Hamiltonians is extended to depend on this new parameter v, and the relationship between this family and the loop models is established. The Gram determinant for the natural bilinear form on these link modules is shown to factorize in terms of an intertwiner i-tilde N d between these link representations and the eigenspaces of S z of the XXZ models. This map is shown to be an isomorphism for generic values of u and v, and the critical curves in the plane of these parameters for which i-tilde N d fails to be an isomorphism are given. (paper)

  9. Linearized Optically Phase-Modulated Fiber Optic Links for Microwave Signal Transport

    Science.gov (United States)

    2009-03-03

    detectors (with internal 50- Ohm resistors) capable of 40-mA dc current per detector. With this link, the linearized SFDR would improve to 133 dB/Hz4/5...the IF) limitation on the signal. All calculations consider the 3dB power loss from the hybrid combiner and 6dB loss from parallel 50- Ohm resistors...283. [25] M. Nazarathy, J. Berger, A. Ley , I. Levi, and Y. Kagan, “Externally Modulated 80 Channel Am Catv Fiber-to-feeder Distribution System Over

  10. [Project EXCEL: Curriculum for Just Desserts, Inc.: Modules 1-6.

    Science.gov (United States)

    Career Resources Development Center, Inc., San Francisco, CA.

    Six curriculum modules for Just Desserts, a San Francisco wholesale bakery company, are presented. Just Desserts was one of four small businesses involved in Project EXCEL, a workplace literacy project that focused on literacy and basic skills training for limited-English-proficient (LEP) workers. The modules are as follows: (1) Bakery Vocabulary…

  11. Direct high-frequency modulation of VCSELs and applications in fibre optic RF and microwave links

    International Nuclear Information System (INIS)

    Larsson, Anders; Carlsson, Christina; Gustavsson, Johan; Haglund, Asa; Modh, Peter; Bengtsson, Joergen

    2004-01-01

    With the rapid development of wireless communication networks there is an increasing demand for efficient and cost-effective transmission and distribution of RF signals. Fibre optic RF links, employing directly modulated semiconductor lasers, provide many of the desired characteristics for such distribution systems and in the search for cost-effective solutions, the vertical cavity surface emitting laser (VCSEL) is of interest. It has therefore been the purpose of this work to investigate whether 850 nm VCSELs fulfil basic performance requirements for fibre optic RF links operating in the low-GHz range. The performance of single- and multimode oxide confined VCSELs has been compared, in order to pin-point limitations and to find the optimum design. Fibre optic RF links using VCSELs and multimode fibres have been assembled and evaluated with respect to performance characteristics of importance for wireless communication systems. We have found that optimized single-mode VCSELs provide the highest performance and that links using such VCSELs and high-bandwidth multimode fibres satisfy the requirements in a number of applications, including cellular systems for mobile communication and wireless local area networks

  12. Simulink models for performance analysis of high speed DQPSK modulated optical link

    International Nuclear Information System (INIS)

    Sharan, Lucky; Rupanshi,; Chaubey, V. K.

    2016-01-01

    This paper attempts to present the design approach for development of simulation models to study and analyze the transmission of 10 Gbps DQPSK signal over a single channel Peer to Peer link using Matlab Simulink. The simulation model considers the different optical components used in link design with their behavior represented initially by theoretical interpretation, including the transmitter topology, Mach Zehnder Modulator(MZM) module and, the propagation model for optical fibers etc. thus allowing scope for direct realization in experimental configurations. It provides the flexibility to incorporate the various photonic components as either user-defined or fixed and, can also be enhanced or removed from the model as per the design requirements. We describe the detailed operation and need of every component model and its representation in Simulink blocksets. Moreover the developed model can be extended in future to support Dense Wavelength Division Multiplexing (DWDM) system, thereby allowing high speed transmission with N × 40 Gbps systems. The various compensation techniques and their influence on system performance can be easily investigated by using such models.

  13. Simulink models for performance analysis of high speed DQPSK modulated optical link

    Energy Technology Data Exchange (ETDEWEB)

    Sharan, Lucky, E-mail: luckysharan@pilani.bits-pilani.ac.in; Rupanshi,, E-mail: f2011222@pilani.bits-pilani.ac.in; Chaubey, V. K., E-mail: vkc@pilani.bits-pilani.ac.in [EEE Department, BITS-Pilani, Rajasthan, 333031 (India)

    2016-03-09

    This paper attempts to present the design approach for development of simulation models to study and analyze the transmission of 10 Gbps DQPSK signal over a single channel Peer to Peer link using Matlab Simulink. The simulation model considers the different optical components used in link design with their behavior represented initially by theoretical interpretation, including the transmitter topology, Mach Zehnder Modulator(MZM) module and, the propagation model for optical fibers etc. thus allowing scope for direct realization in experimental configurations. It provides the flexibility to incorporate the various photonic components as either user-defined or fixed and, can also be enhanced or removed from the model as per the design requirements. We describe the detailed operation and need of every component model and its representation in Simulink blocksets. Moreover the developed model can be extended in future to support Dense Wavelength Division Multiplexing (DWDM) system, thereby allowing high speed transmission with N × 40 Gbps systems. The various compensation techniques and their influence on system performance can be easily investigated by using such models.

  14. Optical-wireless-optical full link for polarization multiplexing quadrature amplitude/phase modulation signal transmission.

    Science.gov (United States)

    Li, Xinying; Yu, Jianjun; Chi, Nan; Zhang, Junwen

    2013-11-15

    We propose and experimentally demonstrate an optical wireless integration system at the Q-band, in which up to 40 Gb/s polarization multiplexing multilevel quadrature amplitude/phase modulation (PM-QAM) signal can be first transmitted over 20 km single-mode fiber-28 (SMF-28), then delivered over a 2 m 2 × 2 multiple-input multiple-output wireless link, and finally transmitted over another 20 km SMF-28. The PM-QAM modulated wireless millimeter-wave (mm-wave) signal at 40 GHz is generated based on the remote heterodyning technique, and demodulated by the radio-frequency transparent photonic technique based on homodyne coherent detection and baseband digital signal processing. The classic constant modulus algorithm equalization is used at the receiver to realize polarization demultiplexing of the PM-QAM signal. For the first time, to the best of our knowledge, we realize the conversion of the PM-QAM modulated wireless mm-wave signal to the optical signal as well as 20 km fiber transmission of the converted optical signal.

  15. Experiences with Designing a Team Project Module for Teaching Teamwork to Students

    OpenAIRE

    Bieliková, Mária

    2005-01-01

    Team projects play an important role in the education of engineers. This paper describes a team project module (called Team project) that is part of a postgraduate course in Informatics. Its main objective is to give students a hands-on experience with different aspects of working in team on a problem. We discuss several aspects that should be considered in designing such module as a part of a curriculum: team formation, team communication, team assessment, problem statement and assignment, d...

  16. Linking project-based mechanisms with domestic greenhouse gas emissions trading schemes

    International Nuclear Information System (INIS)

    Bygrave, S.; Bosi, M.

    2004-01-01

    Although there are a number of possible links between emission trading and project-based mechanisms, the focus of this paper is on linking domestic GHG emission trading schemes with: (1) domestic; and, (2) international (JI and CDM) GHG reduction project activities. The objective is to examine some of the challenges in linking DETs and project-based mechanisms, as well as some possible solutions to address these challenges. The link between JI / CDM and intergovernmental international emissions trading (i.e. Article 17 of the Kyoto Protocol) is defined by the Kyoto Protocol, and therefore is not covered in this paper. The paper is written in the context of: (a) countries adhering to the Kyoto Protocol and elaborating their strategies to meet their GHG emission commitments, including through the use of the emissions trading and project-based mechanisms. For example, the European Union (EU) will be commencing a GHG Emissions Trading Scheme in January 2005, and recently, the Council of ministers and the European Parliament agreed on a text for an EU Linking Directive allowing the use of JI and CDM emission units in the EU Emission Trading Scheme (EU-ETS); and (b) all countries (and/or regions within countries) with GHG emission obligations that may choose to use domestic emissions trading and project-based mechanisms to meet their GHG commitments. The paper includes the following elements: (1) an overview of the different flexibility mechanisms (i.e. GHG emissions trading and PBMs), including a brief description and comparisons between the mechanisms (Section 3); (2) an exploration of the issues that emerge when project-based mechanisms link with domestic emissions trading schemes, as well as possible solutions to address some of the challenges raised (Section 4); (3) a case study examining the EU-ETS and the EU Linking Directive on project-based mechanisms, in particular on how the EU is addressing in a practical context relevant linking issues (Section 5); (4) a

  17. Two-user opportunistic scheduling using hierarchical modulations in wireless networks with heterogenous average link gains

    KAUST Repository

    Hossain, Md Jahangir

    2010-03-01

    Our contribution, in this paper, is two-fold. First, we analyze the performance of a hierarchical modulation-assisted two-best user opportunistic scheduling (TBS) scheme, which was proposed by the authors, in a fading environment where different users have different average link gains. Specifically, we present a new expression for the spectral efficiency (SE) of the users and using this expression, we compare the degrees of fairness (DOF) of the TBS scheme with that of classical single user opportunistic scheduling schemes, namely, absolute carrier-to-noise ratio (CNR) based single-best user scheduling (SBS) and normalized CNR based proportional fair scheduling (PFS) schemes. The second contribution is that we propose a new hybrid two-user opportunistic scheduling (HTS) scheme based on our earlier proposed TBS scheme. This HTS scheme selects the first user based on the largest absolute CNR value among all the users while the second user is selected based on the ratios of the absolute CNRs to the corresponding average CNRs of the remaining users. The total transmission rate i.e., the constellation size is selected according to the absolute CNR of the first best user. The total transmission rate is then allocated among these selected users by joint consideration of their absolute CNRs and allocated number of information bit(s) are transmitted to them using hierarchical modulations. Numerical results are presented for a fading environment where different users experience independent but non-identical (i.n.d.) channel fading. These selected numerical results show that the proposed HTS scheme can considerably increase the system\\'s fairness without any degradation of the link spectral efficiency (LSE) i.e., the multiuser diversity gain compared to the classical SBS scheme. These results also show that the proposed HTS scheme has a lower fairness in comparison to the PFS scheme which suffers from a considerable degradation in LSE. © 2010 IEEE.

  18. Environmental conditions can modulate the links among oxidative stress, age, and longevity.

    Science.gov (United States)

    Marasco, Valeria; Stier, Antoine; Boner, Winnie; Griffiths, Kate; Heidinger, Britt; Monaghan, Pat

    2017-06-01

    Understanding the links between environmental conditions and longevity remains a major focus in biological research. We examined within-individual changes between early- and mid-adulthood in the circulating levels of four oxidative stress markers linked to ageing, using zebra finches (Taeniopygia guttata): a DNA damage product (8-hydroxy-2'-deoxyguanosine; 8-OHdG), protein carbonyls (PC), non-enzymatic antioxidant capacity (OXY), and superoxide dismutase activity (SOD). We further examined whether such within-individual changes differed among birds living under control (ad lib food) or more challenging environmental conditions (unpredictable food availability), having previously found that the latter increased corticosterone levels when food was absent but improved survival over a three year period. Our key findings were: (i) 8-OHdG and PC increased with age in both environments, with a higher increase in 8-OHdG in the challenging environment; (ii) SOD increased with age in the controls but not in the challenged birds, while the opposite was true for OXY; (iii) control birds with high levels of 8-OHdG died at a younger age, but this was not the case in challenged birds. Our data clearly show that while exposure to the potentially damaging effects of oxidative stress increases with age, environmental conditions can modulate the pace of this age-related change. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Modulation and modeling of monoclonal antibody N-linked glycosylation in mammalian cell perfusion reactors.

    Science.gov (United States)

    Karst, Daniel J; Scibona, Ernesto; Serra, Elisa; Bielser, Jean-Marc; Souquet, Jonathan; Stettler, Matthieu; Broly, Hervé; Soos, Miroslav; Morbidelli, Massimo; Villiger, Thomas K

    2017-09-01

    Mammalian cell perfusion cultures are gaining renewed interest as an alternative to traditional fed-batch processes for the production of therapeutic proteins, such as monoclonal antibodies (mAb). The steady state operation at high viable cell density allows the continuous delivery of antibody product with increased space-time yield and reduced in-process variability of critical product quality attributes (CQA). In particular, the production of a confined mAb N-linked glycosylation pattern has the potential to increase therapeutic efficacy and bioactivity. In this study, we show that accurate control of flow rates, media composition and cell density of a Chinese hamster ovary (CHO) cell perfusion bioreactor allowed the production of a constant glycosylation profile for over 20 days. Steady state was reached after an initial transition phase of 6 days required for the stabilization of extra- and intracellular processes. The possibility to modulate the glycosylation profile was further investigated in a Design of Experiment (DoE), at different viable cell density and media supplement concentrations. This strategy was implemented in a sequential screening approach, where various steady states were achieved sequentially during one culture. It was found that, whereas high ammonia levels reached at high viable cell densities (VCD) values inhibited the processing to complex glycan structures, the supplementation of either galactose, or manganese as well as their synergy significantly increased the proportion of complex forms. The obtained experimental data set was used to compare the reliability of a statistical response surface model (RSM) to a mechanistic model of N-linked glycosylation. The latter outperformed the response surface predictions with respect to its capability and reliability in predicting the system behavior (i.e., glycosylation pattern) outside the experimental space covered by the DoE design used for the model parameter estimation. Therefore, we can

  20. Linking renewable energy CDM projects and TGC schemes: An analysis of different options

    Energy Technology Data Exchange (ETDEWEB)

    Del Rio, Pablo [Department of Economics and Business, Facultad de Ciencias Juridicas y Sociales, Universidad de Castilla-La Mancha, C/ Cobertizo de S. Pedro Martir s/n., Toledo-45071 (Spain)]. E-mail: pablo.rio@uclm.es

    2006-11-15

    Renewable energy CDM (RE-CDM) projects encourage cost-effective GHG mitigation and enhanced sustainable development opportunities for the host countries. CERs from CDM projects include the value of the former benefits (i.e., 'climate change benefits'), whereas the second can be given value through the issuing and trading of tradable green certificates (TGCs). Countries could agree to trade these TGCs, leading to additional revenues for the investors in renewable energy projects and, therefore, further encouraging the deployment of CDM projects, currently facing significant barriers. However, the design of a combination of CDM projects and TGC schemes raises several conflicting issues and leads to trade-offs. This paper analyses these issues, identifies the alternatives that may exist to link TGC schemes with RE-CDM projects and analyses the impacts of those options on different variables and actors.

  1. Linking renewable energy CDM projects and TGC schemes: An analysis of different options

    International Nuclear Information System (INIS)

    Del Rio, Pablo

    2006-01-01

    Renewable energy CDM (RE-CDM) projects encourage cost-effective GHG mitigation and enhanced sustainable development opportunities for the host countries. CERs from CDM projects include the value of the former benefits (i.e., 'climate change benefits'), whereas the second can be given value through the issuing and trading of tradable green certificates (TGCs). Countries could agree to trade these TGCs, leading to additional revenues for the investors in renewable energy projects and, therefore, further encouraging the deployment of CDM projects, currently facing significant barriers. However, the design of a combination of CDM projects and TGC schemes raises several conflicting issues and leads to trade-offs. This paper analyses these issues, identifies the alternatives that may exist to link TGC schemes with RE-CDM projects and analyses the impacts of those options on different variables and actors

  2. Exploring Protein Structure and Dynamics through a Project-Oriented Biochemistry Laboratory Module

    Science.gov (United States)

    Lipchock, James M.; Ginther, Patrick S.; Douglas, Bonnie B.; Bird, Kelly E.; Loria, J. Patrick

    2017-01-01

    Here, we present a 10-week project-oriented laboratory module designed to provide a course-based undergraduate research experience in biochemistry that emphasizes the importance of biomolecular structure and dynamics in enzyme function. This module explores the impact of mutagenesis on an important active site loop for a biomedically-relevant…

  3. Project T.E.A.M. (Technical Education Advancement Modules). Introduction to Statistical Process Control.

    Science.gov (United States)

    Billings, Paul H.

    This instructional guide, one of a series developed by the Technical Education Advancement Modules (TEAM) project, is a 6-hour introductory module on statistical process control (SPC), designed to develop competencies in the following skill areas: (1) identification of the three classes of SPC use; (2) understanding a process and how it works; (3)…

  4. Photovoltaic module with integrated power conversion and interconnection system - the European project PV-MIPS

    OpenAIRE

    Henze, N.; Engler, A.; Zacharias, P.

    2006-01-01

    Within the 6th framework program funded by the European Commission the project PV-MIPS (Photovoltaic Module with Integrated Power Conversion System) was launched in November 2004. Together with eleven European partners from Germany, Austria, Greece and the Netherlands a solar module with integrated in-verter shall be developed that can feed solar electricity directly into the grid. The challenging objective of the project is to reduce the total costs of a PV system. At the same time lifetime ...

  5. Evaluation of a Team Project Based Learning Module for Developing Employability Skills

    OpenAIRE

    Janice Whatley

    2012-01-01

    This paper presents a case study, in which a new module, aimed at enhancing students’ employ-ability skills, is evaluated. Employability skills for graduates from higher education are regarded as essential outcomes from their degree programmes, but it can be difficult to provide appropriate opportunities to develop these skills in the context of their studies. This paper describes a new module, called Live Projects, designed to provide project based learning on campus, but involv-ing local bu...

  6. Advances in the ROBLINKS project on long-range shallow-water robust acoustic communciation links

    NARCIS (Netherlands)

    Gijzen, M.B. van; Walree, P.A. van; Cano, D.; Passerieux, J-M.; Waldhorst, A.; Weber, R.

    2000-01-01

    Within the ROBLINKS project waveforms and algorithms have been developed to establish robust underwater acoustic communication links with high data rates in shallow water. To evaluate the signalling schemes, a wide range of experiments has been performed during a sea trial that has been held in May

  7. The link class project : Collaborative virtual teams between Peru and The Netherlands

    NARCIS (Netherlands)

    Olivos Rossini, L.M.; Rincon, Sandra; Rutkowski, Anne-Francoise

    2015-01-01

    The Link Class Project presented in this article provides an example of established collaborative group activities to negotiate and build a report together in virtual teams composed of students at Universidad ESAN, Lima (Peru) and Tilburg University, Tilburg (Netherlands). It further analyzes the

  8. Reconfigurable digital receiver for 8PSK subcarrier multiplexed and 16QAM single carrier phase‐modulated radio over fiber links

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Yu, Xianbin

    2011-01-01

    A reconfigurable digital receiver based on the k‐means algorithm is proposed for phase‐modulated subcarrier multiplexed (SCM) and quadrature amplitude‐modulated single carrier, phase‐modulated radio‐over‐fiber links. We report successful demodulation after 40 km single mode fiber transmission wit...... with three 50 Mbaud 8PSK SCM signals and a 312.5 Mbaud 16QAM single carrier. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:1015–1018, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25905...

  9. Energy for climate in Europe. An assessment of energy policies with climate-relevance. The LinkS Project.

    Energy Technology Data Exchange (ETDEWEB)

    Ruud, Audun; Knudsen, Joergen K.; Jacobsen, Gerd B.

    2011-07-01

    The LinkS project aims at providing a better linkage between perspectives and projections for global climate policy development and regional energy systems, by linking relevant modelling tools. The present report provides a specific focus on energy policy measures within the EY with climate relevance. The EU has in recent years aimed at reinforcing the linkage between the climate and energy policies, both at strategic and operational levels. The EU has pledged itself to reduce its greenhouse gas (GHG) emissions with 8 percent by 2008-12 as compared to the 1990 level, and by 20 percent by 2020 as compared to the as compared to the 2005 level. The EU-27 reduced it GHG emissions with 11,3 percent in 1990-2008. The 2020-target, however, will require stronger efforts and energy is a key sector: The EU has decided that 20 percent of the energy must be renewable, and that the energy usage in 2020 is to be 20 per sent more efficient than in 2005. A number of policy strategies, measures and legislation are formulated to fulfil these targets. In order to highlight the potential of these measures, this report specifically addresses the drivers and limitations given the existing decision-making structures in the EU. The methodology employed is mainly qualitative, based on document analysis and a review of secondary literature. Climate-change mitigation is in principle based on supra-national decision-making, but unanimity among all Eu Member States is still required in critical issues related to the energy sector. In addition, the national follow-up of the targets constitutes a particular challenge. This is here illustrated by the cases of Denmark and Norway. Energy policy is also substantially characterised by several conflicting interests between the Member States, resulting in diverging policy priorities. It is, therefore, an open question whether the EU will succeed in fulfilling its 20/20/20 percent targets by 2020, and will be the actual role of energy within the climate

  10. Projective Synchronization in Modulated Time-Delayed Chaotic Systems Using an Active Control Approach

    International Nuclear Information System (INIS)

    Feng Cun-Fang; Wang Ying-Hai

    2011-01-01

    Projective synchronization in modulated time-delayed systems is studied by applying an active control method. Based on the Lyapunov asymptotical stability theorem, the controller and sufficient condition for projective synchronization are calculated analytically. We give a general method with which we can achieve projective synchronization in modulated time-delayed chaotic systems. This method allows us to adjust the desired scaling factor arbitrarily. The effectiveness of our method is confirmed by using the famous delay-differential equations related to optical bistable or hybrid optical bistable devices. Numerical simulations fully support the analytical approach. (general)

  11. Developing Project Based Learning E-Module for the Course of Video Editing

    Directory of Open Access Journals (Sweden)

    Ketut Krisnayuni

    2017-04-01

    Full Text Available This study examined the development of an electronic module for the course of video editing and analyzed the students’ response of the e-module. A waterfall model was adopted in the development process of the e-module that consisted of five stages namely (1 analysis; (2 design; (3 implementation; (4 evaluation; and (5 maintenance. The subjects of this study were the students of class XI at SMK Negeri 1 Sukasada. Project Based Learning was used as the basis of the e-module development as the most relevant learning model to meet the students’needs and the schools’ situation. The data of the students’ response about the e-module were collected through a questionnaire. The students’ response was very positive indicated by the mean score of 94,37. It was concluded that the developed e-modul was categorized as very good.

  12. Permitting plan for project W-236B, initial pretreatment module

    International Nuclear Information System (INIS)

    Tollefson, K.S.

    1995-01-01

    The Tank Waste Remediation System pretreatment process mission is to separate high-level and low-level waste fractions. A comprehensive review of environmental regulations has indicated that several environmental reviews, permits, and approvals are required before construction and operation of the facility. This revised document provides a summary of permit application data requirements, alternative strategies for permit completion and approval, as well as the probability of success for each alternative for the Initial Pretreatment Module resulting from recent revisions to the Tri-Party Agreement

  13. Integrated InP frequency discriminator for Phase-modulated microwave photonic links.

    Science.gov (United States)

    Fandiño, J S; Doménech, J D; Muñoz, P; Capmany, J

    2013-02-11

    We report the design, fabrication and characterization of an integrated frequency discriminator on InP technology for microwave photonic phase modulated links. The optical chip is, to the best of our knowledge, the first reported in an active platform and the first to include the optical detectors. The discriminator, designed as a linear filter in intensity, features preliminary SFDR values the range between 67 and 79 dB.Hz(2/3) for signal frequencies in the range of 5-9 GHz limited, in principle, by the high value of the optical losses arising from the use of several free space coupling devices in our experimental setup. As discussed, these losses can be readily reduced by the use of integrated spot-size converters improving the SFDR by 17.3 dB (84-96 dB.Hz(2/3)). Further increase up to a range of (104-116 dB.Hz(2/3)) is possible by reducing the system noise eliminating the EDFA employed in the setup and using a commercially available laser source providing higher output power and lower relative intensity noise. Other paths for improvement requiring a filter redesign to be linear in the optical field are also discussed.

  14. Integrin-linked kinase interactions with ELMO2 modulate cell polarity.

    Science.gov (United States)

    Ho, Ernest; Irvine, Tames; Vilk, Gregory J A; Lajoie, Gilles; Ravichandran, Kodi S; D'Souza, Sudhir J A; Dagnino, Lina

    2009-07-01

    Cell polarization is a key prerequisite for directed migration during development, tissue regeneration, and metastasis. Integrin-linked kinase (ILK) is a scaffold protein essential for cell polarization, but very little is known about the precise mechanisms whereby ILK modulates polarization in normal epithelia. Elucidating these mechanisms is essential to understand tissue morphogenesis, transformation, and repair. Here we identify a novel ILK protein complex that includes Engulfment and Cell Motility 2 (ELMO2). We also demonstrate the presence of RhoG in ILK-ELMO2 complexes, and the localization of this multiprotein species specifically to the leading lamellipodia of polarized cells. Significantly, the ability of RhoG to bind ELMO is crucial for ILK induction of cell polarization, and the joint expression of ILK and ELMO2 synergistically promotes the induction of front-rear polarity and haptotactic migration. This places RhoG-ELMO2-ILK complexes in a key position for the development of cell polarity and forward movement. Although ILK is a component of many diverse multiprotein species that may contribute to cell polarization, expression of dominant-negative ELMO2 mutants is sufficient to abolish the ability of ILK to promote cell polarization. Thus, its interaction with ELMO2 and RhoG is essential for the ability of ILK to induce front-rear cell polarity.

  15. Modulation of integrin-linked kinase nucleo-cytoplasmic shuttling by ILKAP and CRM1.

    Science.gov (United States)

    Nakrieko, Kerry-Ann; Vespa, Alisa; Mason, David; Irvine, Timothy S; D'Souza, Sudhir J A; Dagnino, Lina

    2008-07-15

    Integrin-linked kinase (ILK) plays key roles in a variety of cell functions, including cell proliferation, adhesion and migration. Within the cell, ILK localizes to multiple sites, including the cytoplasm, focal adhesion complexes that mediate cell adhesion to extracellular substrates, as well as cell-cell junctions in epidermal keratinocytes. Central to understanding ILK function is the elucidation of the mechanisms that regulate its subcellular localization. We now demonstrate that ILK is imported into the nucleus through sequences in its N-terminus, via active transport mechanisms that involve nuclear pore complexes. In addition, nuclear ILK can be rapidly exported into the cytoplasm through a CRM1-dependent pathway, and its export is enhanced by the type 2C protein phosphatase ILKAP. Nuclear localization of ILK in epidermal keratinocytes is associated with increased DNA synthesis, which is sensitive to inhibition by ILKAP. Our studies demonstrate the importance for keratinocyte proliferation of ILK regulation through changes in its subcellular localization, and establish ILKAP and CRM1 as pivotal modulators of ILK subcellular distribution and activity in these cells.

  16. Integrin-linked kinase and ELMO2 modulate recycling endosomes in keratinocytes.

    Science.gov (United States)

    Ho, Ernest; Ivanova, Iordanka A; Dagnino, Lina

    2016-12-01

    The formation of tight cell-cell junctions is essential in the epidermis for its barrier properties. In this tissue, keratinocytes follow a differentiation program tightly associated with their movement from the innermost basal to the outer suprabasal layers, and with changes in their cell-cell adhesion profile. Intercellular adhesion in keratinocytes is mediated through cell-cell contacts, including E-cadherin-based adherens junctions. Although the mechanisms that mediate E-cadherin delivery to the plasma membrane have been widely studied in simple epithelia, this process is less well understood in the stratified epidermis. In this study, we have investigated the role of Engulfment and Cell Motility 2 (ELMO2) and integrin-linked kinase (ILK) in the positioning of E-cadherin-containing recycling endosomes during establishment of cell-cell contacts in differentiating keratinocytes. We now show that induction of keratinocyte differentiation by Ca 2+ is accompanied by localization of ELMO2 and ILK to Rab4- and Rab11a-containing recycling endosomes. The positioning of long-loop Rab11a-positive endosomes at areas adjacent to cell-cell contacts is disrupted in ELMO2- or ILK-deficient keratinocytes, and is associated with impaired localization of E-cadherin to cell borders. Our studies show a previously unrecognized role for ELMO2 and ILK in modulation of endosomal positioning, which may play key roles in epidermal sheet maintenance and permeability barrier function. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. EpiCollect+: linking smartphones to web applications for complex data collection projects.

    Science.gov (United States)

    Aanensen, David M; Huntley, Derek M; Menegazzo, Mirko; Powell, Chris I; Spratt, Brian G

    2014-01-01

    Previously, we have described the development of the generic mobile phone data gathering tool, EpiCollect, and an associated web application, providing two-way communication between multiple data gatherers and a project database. This software only allows data collection on the phone using a single questionnaire form that is tailored to the needs of the user (including a single GPS point and photo per entry), whereas many applications require a more complex structure, allowing users to link a series of forms in a linear or branching hierarchy, along with the addition of any number of media types accessible from smartphones and/or tablet devices (e.g., GPS, photos, videos, sound clips and barcode scanning). A much enhanced version of EpiCollect has been developed (EpiCollect+). The individual data collection forms in EpiCollect+ provide more design complexity than the single form used in EpiCollect, and the software allows the generation of complex data collection projects through the ability to link many forms together in a linear (or branching) hierarchy. Furthermore, EpiCollect+ allows the collection of multiple media types as well as standard text fields, increased data validation and form logic. The entire process of setting up a complex mobile phone data collection project to the specification of a user (project and form definitions) can be undertaken at the EpiCollect+ website using a simple 'drag and drop' procedure, with visualisation of the data gathered using Google Maps and charts at the project website. EpiCollect+ is suitable for situations where multiple users transmit complex data by mobile phone (or other Android devices) to a single project web database and is already being used for a range of field projects, particularly public health projects in sub-Saharan Africa. However, many uses can be envisaged from education, ecology and epidemiology to citizen science.

  18. Modulation Formats for Beyond-100Gbps Ethernet Optical Links – A Review of Research

    DEFF Research Database (Denmark)

    Jensen, Jesper Bevensee; Iglesias Olmedo, Miguel; Tafur Monroy, Idelfonso

    2013-01-01

    The current increase in data-centers traffic and cloud-based services presents a formidable challenge for optical interconnects. We examine these challenges, and review recent breakthroughs in advanced modulation formats formats for intensity modulation - direct detection....

  19. RIVER INTER-LINKING (RIL) PROJECT: A QUESTION ON INDIAN FEDERALISM.

    OpenAIRE

    Shazia Waheed; Pradip Kumar Jha.

    2017-01-01

    The Supreme Court of India, in 2002 directed the central government to link major Indian rivers within 10 years. In December 2002, the government appointed a task force on interlinking of 37 rivers and the dead line was extended by 2016. The RIL project not only raises national issue but also give way to international conflict in South Asia over sharing of river waters. The paper examines the impact of the RIL project on the paradigms and working of Indian federalism. It is based on triangula...

  20. Cryogenic digital data links for the liquid argon time projection chamber

    International Nuclear Information System (INIS)

    Liu, T; Gong, D; Liu, C; Xiang, A C; Ye, J; Hou, S; Su, D-S; Teng, P-K

    2012-01-01

    In this paper we present the cryogenic functionality of the components of data links for the Liquid Argon Time Projection Chamber (LArTPC), a potential far site detector technology of the Long-Baseline Neutrino Experiment (LBNE). We have confirmed that an LVDS driver can drive a 20-meter CAT5E twisted pair up to 1 gigabit per second at the liquid nitrogen temperature (77 K). We have verified that a commercial-off-the-shelf (COTS) serializer, a laser diode driver, laser diodes, optical fibers and connectors, and field-programming gate arrays (FPGA's) continue to function at 77 K. A variety of COTS resistors and capacitors have been tested at 77 K. All tests we have conducted show that the cryogenic digital data links for the liquid argon time projection chamber are promising.

  1. The Link Class Project: Collaborative virtual teams between Peru and The Netherlands

    OpenAIRE

    Mariella Olivos Rossini; Sandra Rincón; Anne-Francoise Rutkowski

    2015-01-01

    The Link Class Project presented in this article provides an example of established collaborative group activities to negotiate and build a report together in virtual teams composed of students at Universidad ESAN, Lima (Peru) and Tilburg University, Tilburg (Netherlands). It further analyzes the effects of a campus based internationalization strategy supported by the use of technology. Based on previous experiences with virtual classrooms, the authors adhere to the ancient Chinese philosophe...

  2. Superconducting link bus design for the accelerator project for upgrade of LHC

    International Nuclear Information System (INIS)

    Nobrega, F.; Brandt, J.; Cheban, S.; Feher, S.; Kaducak, M.; Kashikhin, V.; Peterson, T.

    2011-01-01

    The Accelerator Project for Upgrade of LHC (APUL) is a U.S. project participating in and contributing to CERN's Large Hadron Collider (LHC) upgrade program. Fermi National Accelerator Laboratory in collaboration with Brookhaven National Laboratory was developing sub-systems for the upgrade of the LHC final focus magnet systems. Part of the upgrade called for various lengths of superconducting power transmission lines known as SC Links which were up to 100 m long. The SC Link electrically connects the current leads in the Distribution Feed Boxes to the interaction region magnets. The SC Link is an extension of the magnet bus housed within a cryostat. The present concept for the bus consists of 22 power cables, 4 x 13 kA, 2 x 7 kA, 8 x 2.5 kA and 8 x 0.6 kA bundled into one bus. Different cable and strand possibilities were considered for the bus design including Rutherford cable. The Rutherford cable bus design potentially would have required splices at each sharp elbow in the SC Link. The advantage of the round bus design is that splices are only required at each end of the bus during installation at CERN. The round bus is very flexible and is suitable for pulling through the cryostat. Development of the round bus prototype and of 2 splice designs is described in this paper. Magnetic analysis and mechanical test results of the 13 kA cable and splices are presented.

  3. FERC approves process for Lake Erie link: Project meets significant regulatory milestone

    International Nuclear Information System (INIS)

    Anon

    2002-01-01

    The Federal Electric Regulatory Commission (FERC) of the United States has issued an order to TransEnergie US Ltd., and Hydro One Inc., authorizing the sale of transmission rights for the proposed Lake Erie link. This project will consists of bi-directional high voltage direct current facilities connecting the transmission grids of Ontario, Canada and the United States. The sale is authorized to proceed via a non-discriminatory 'open season' process. The project will consist of buried underwater cables under Lake Erie connecting the transmission systems near Simcoe, Ontario with those in the US at either, or both, of Springfield, Pennsylvania, and Ashtabula, Ohio. The project will provide an increase in transmission capability of up to 975 MW between the electric control areas of the Ontario Independent Electricity Market Operator, the East Central Area Reliability Coordination Agreement in Ohio and the Pennsylvania-New Jersey-Maryland Interconnection. The Lake Erie Link will be financially supported by those consumers who see value in the associated transmission rights, rather than through the regulated rates paid by transmission customers in general. The article provides an overview of the background of the Lake Erie Link, the cable system, the converter station, and the potential economic benefits

  4. Lifetime Estimation of DC-link Capacitors in a Single-phase Converter with an Integrated Active Power Decoupling Module

    DEFF Research Database (Denmark)

    Ma, Siyuan; Wang, Haoran; Tang, Junchaojie

    2016-01-01

    In single-phase inverters, DC-link capacitors are installed at the DC-link to buffer the ripple power between the AC side and DC side. Active decoupling methods introduce additional circuits at the DC side or AC side to partially or fully supply the ripple power. So that the demanded DC-link capa......In single-phase inverters, DC-link capacitors are installed at the DC-link to buffer the ripple power between the AC side and DC side. Active decoupling methods introduce additional circuits at the DC side or AC side to partially or fully supply the ripple power. So that the demanded DC......-link capacitor capacitance can be decreased. However, few research is about the effect of DC side and AC side decoupling on the DC-link capacitor reliability considering its electro-thermal stresses. This paper presents a quantitative analysis on the lifetime of capacitors with power decoupling circuits...... at the DC side and AC side, respectively. The ripple current spectrum of the capacitors is obtained by double Fourier analysis of a H-bridge inverter with natural sampling PWM modulation. A study case is demonstrated by a 2,000 W H-bridge inverter with 400 V DC-link voltage....

  5. Bit-error-rate performance analysis of self-heterodyne detected radio-over-fiber links using phase and intensity modulation

    DEFF Research Database (Denmark)

    Yin, Xiaoli; Yu, Xianbin; Tafur Monroy, Idelfonso

    2010-01-01

    We theoretically and experimentally investigate the performance of two self-heterodyne detected radio-over-fiber (RoF) links employing phase modulation (PM) and quadrature biased intensity modulation (IM), in term of bit-error-rate (BER) and optical signal-to-noise-ratio (OSNR). In both links, self...

  6. The Link between Microbial Diversity and Nitrogen Cycling in Marine Sediments Is Modulated by Macrofaunal Bioturbation.

    Science.gov (United States)

    Yazdani Foshtomi, Maryam; Braeckman, Ulrike; Derycke, Sofie; Sapp, Melanie; Van Gansbeke, Dirk; Sabbe, Koen; Willems, Anne; Vincx, Magda; Vanaverbeke, Jan

    2015-01-01

    The marine benthic nitrogen cycle is affected by both the presence and activity of macrofauna and the diversity of N-cycling microbes. However, integrated research simultaneously investigating macrofauna, microbes and N-cycling is lacking. We investigated spatio-temporal patterns in microbial community composition and diversity, macrofaunal abundance and their sediment reworking activity, and N-cycling in seven subtidal stations in the Southern North Sea. Our results indicated that bacteria (total and β-AOB) showed more spatio-temporal variation than archaea (total and AOA) as sedimentation of organic matter and the subsequent changes in the environment had a stronger impact on their community composition and diversity indices in our study area. However, spatio-temporal patterns of total bacterial and β-AOB communities were different and related to the availability of ammonium for the autotrophic β-AOB. Highest bacterial richness and diversity were observed in June at the timing of the phytoplankton bloom deposition, while richness of β-AOB as well as AOA peaked in September. Total archaeal community showed no temporal variation in diversity indices. Distance based linear models revealed that, independent from the effect of grain size and the quality and quantity of sediment organic matter, nitrification and N-mineralization were affected by respectively the diversity of metabolically active β-AOB and AOA, and the total bacteria, near the sediment-water interface. Separate models demonstrated a significant and independent effect of macrofaunal activities on community composition and richness of total bacteria, and diversity indices of metabolically active AOA. Diversity of β-AOB was significantly affected by macrofaunal abundance. Our results support the link between microbial biodiversity and ecosystem functioning in marine sediments, and provided broad correlative support for the hypothesis that this relationship is modulated by macrofaunal activity. We

  7. The Link between Microbial Diversity and Nitrogen Cycling in Marine Sediments Is Modulated by Macrofaunal Bioturbation.

    Directory of Open Access Journals (Sweden)

    Maryam Yazdani Foshtomi

    Full Text Available The marine benthic nitrogen cycle is affected by both the presence and activity of macrofauna and the diversity of N-cycling microbes. However, integrated research simultaneously investigating macrofauna, microbes and N-cycling is lacking. We investigated spatio-temporal patterns in microbial community composition and diversity, macrofaunal abundance and their sediment reworking activity, and N-cycling in seven subtidal stations in the Southern North Sea.Our results indicated that bacteria (total and β-AOB showed more spatio-temporal variation than archaea (total and AOA as sedimentation of organic matter and the subsequent changes in the environment had a stronger impact on their community composition and diversity indices in our study area. However, spatio-temporal patterns of total bacterial and β-AOB communities were different and related to the availability of ammonium for the autotrophic β-AOB. Highest bacterial richness and diversity were observed in June at the timing of the phytoplankton bloom deposition, while richness of β-AOB as well as AOA peaked in September. Total archaeal community showed no temporal variation in diversity indices.Distance based linear models revealed that, independent from the effect of grain size and the quality and quantity of sediment organic matter, nitrification and N-mineralization were affected by respectively the diversity of metabolically active β-AOB and AOA, and the total bacteria, near the sediment-water interface. Separate models demonstrated a significant and independent effect of macrofaunal activities on community composition and richness of total bacteria, and diversity indices of metabolically active AOA. Diversity of β-AOB was significantly affected by macrofaunal abundance. Our results support the link between microbial biodiversity and ecosystem functioning in marine sediments, and provided broad correlative support for the hypothesis that this relationship is modulated by macrofaunal

  8. Prometheus Project Reactor Module Final Report, For Naval Reactors Information

    International Nuclear Information System (INIS)

    MJ Wollman; MJ Zika

    2006-01-01

    The Naval Reactors Prime Contractor Team (NRPCT) led the development of a power plant for a civilian nuclear electric propulsion (NEP) system concept as part of the Prometheus Project. This report provides a summary of the facts, technical insights, and programmatic perspectives gained from this two-year program. The Prometheus Project experience has been extensively documented to better position the US for future space reactor development. Major Technological and engineering challenges exist to develop a system that provides useful electric power from a nuclear fission heat source operating in deep space. General issues include meeting mission requirements in a system that has a mass low enough to launch from earth while assuring public safety and remaining safely shutdown during credible launch accidents. These challenges may be overcome in the future if there is a space mission with a compelling need for nuclear power to drive development. Past experience and notional mission requirements indicate that any useful space reactor system will be unlike past space reactors and existing terrestrial reactors

  9. Prototype Biology-Based Radiation Risk Module Project

    Science.gov (United States)

    Terrier, Douglas; Clayton, Ronald G.; Patel, Zarana; Hu, Shaowen; Huff, Janice

    2015-01-01

    Biological effects of space radiation and risk mitigation are strategic knowledge gaps for the Evolvable Mars Campaign. The current epidemiology-based NASA Space Cancer Risk (NSCR) model contains large uncertainties (HAT #6.5a) due to lack of information on the radiobiology of galactic cosmic rays (GCR) and lack of human data. The use of experimental models that most accurately replicate the response of human tissues is critical for precision in risk projections. Our proposed study will compare DNA damage, histological, and cell kinetic parameters after irradiation in normal 2D human cells versus 3D tissue models, and it will use a multi-scale computational model (CHASTE) to investigate various biological processes that may contribute to carcinogenesis, including radiation-induced cellular signaling pathways. This cross-disciplinary work, with biological validation of an evolvable mathematical computational model, will help reduce uncertainties within NSCR and aid risk mitigation for radiation-induced carcinogenesis.

  10. Socio-Economical, Environmental Evaluation of Ken-Betwa River Link Project, India

    Directory of Open Access Journals (Sweden)

    Pathak Hemant

    2016-10-01

    Full Text Available The India's ambitious Rs 9,393 crore Ken-Betwa river interlinking project will impact very significantly on Socio-economic life of two million people of Bundelkhand region, India. Water is an important input for survival and sustenance of life. The demand of this natural gift has been increasing exponentially. This ambitious project will help us in irrigation, potable water, cheap transportation, electricity as well as a source of livelihood for our ever increasing population. In Bundelkhand region, there is a severe problem of lack of irrigation in one region and water logging in others. Damage to crops due to drought and pitiable drainage facility could be managed. The objectives of the paper are to study socio-economical issues and environmental challenges in Ken-Betwa River link in India and to study environmental impact of this Project.

  11. The Hands-On Optics Project: a demonstration of module 3-magnificent magnifications

    Science.gov (United States)

    Pompea, Stephen M.; Sparks, Robert T.; Walker, Constance E.

    2014-07-01

    The Hands-On Optics project offers an example of a set of instructional modules that foster active prolonged engagement. Developed by SPIE, OSA, and NOAO through funding from the U.S. National Science Foundation, the modules were originally designed for afterschool settings and museums. However, because they were based on national standards in mathematics, science, and technology, they were easily adapted for use in classrooms. The philosophy and implementation strategies of the six modules will be described as well as lessons learned in training educators. The modules were implementing with the help of optics industry professionals who served as expert volunteers to assist educators. A key element of the modules was that they were developed around an understanding of optics misconceptions and used culminating activities in each module as a form of authentic assessment. Thus student achievement could be measured by evaluating the actual product created by each student in applying key concepts, tools, and applications together at the end of each module. The program used a progression of disciplinary core concepts to build an integrated sequence and crosscutting ideas and practices to infuse the principles of the modern electro-optical field into the modules. Whenever possible, students were encouraged to experiment and to create, and to pursue inquiry-based approaches. The result was a program that had high appeal to regular as well as gifted students.

  12. Building a partnership to evaluate school-linked health services: the Cincinnati School Health Demonstration Project.

    Science.gov (United States)

    Rose, Barbara L; Mansour, Mona; Kohake, Kelli

    2005-12-01

    The Cincinnati School Health Demonstration Project was a 3-year collaboration that evaluated school-linked health services in 6 urban elementary (kindergarten to eighth grade) schools. Partners from the Cincinnati Health Department, Cincinnati Public Schools, Cincinnati Children's Hospital Medical Center, and The Health Foundation of Greater Cincinnati wanted to determine if levels of school-linked care made a difference in student quality of life, school connectedness, attendance, emergency department use, and volume of referrals to health care specialists. School nurses, principals and school staff, parents and students, upper-level managers, and health service researchers worked together over a 2.5-year period to learn about and use new technology to collect information on student health, well-being, and outcome measures. Varying levels of school health care intervention models were instituted and evaluated. A standard model of care was compared with 2 models of enhanced care and service. The information collected from students, parents, nurses, and the school system provided a rich database on the health of urban children. School facilities, staffing, and computer technology, relationship building among stakeholders, extensive communication, and high student mobility were factors that influenced success and findings of the project. Funding for district-wide computerization and addition of school health staff was not secured by the end of the demonstration project; however, relationships among the partners endured and paved the way for future collaborations designed to better serve urban school children in Cincinnati.

  13. The Disk Mass project; science case for a new PMAS IFU module

    NARCIS (Netherlands)

    Verheijen, M. A. W.; Bershady, M. A.; Andersen, D. R.; Swaters, R. A.; Westfall, K.; Kelz, A.; Roth, M. M.

    2004-01-01

    We present our Disk Mass project as the main science case for building a new fiber IFU-module for the PMAS spectrograph, currently mounted at the Cassegrain focus of the 3.5m telescope on Calar Alto. Compared to traditional long-slit observations, the large light collecting power of 2-dimensional

  14. Project T.E.A.M. (Technical Education Advancement Modules). Advanced Statistical Process Control.

    Science.gov (United States)

    Dunlap, Dale

    This instructional guide, one of a series developed by the Technical Education Advancement Modules (TEAM) project, is a 20-hour advanced statistical process control (SPC) and quality improvement course designed to develop the following competencies: (1) understanding quality systems; (2) knowing the process; (3) solving quality problems; and (4)…

  15. Preparation for Instruction. A Module of Instruction in Teacher Education. Prepared for Project RAFT.

    Science.gov (United States)

    Handley, Herbert M., Ed.

    This module, developed by the Research Applications for Teaching (RAFT) project, was written to assist students to write lesson plans that are effective and interactive. Students are given directions for the preparation of behavioral objectives and for the selection of appropriate instructional methodologies to meet the widely varying needs of…

  16. An overview of Space Communication Artificial Intelligence for Link Evaluation Terminal (SCAILET) Project

    Science.gov (United States)

    Shahidi, Anoosh K.; Schlegelmilch, Richard F.; Petrik, Edward J.; Walters, Jerry L.

    1991-11-01

    A software application to assist end-users of the link evaluation terminal (LET) for satellite communications is being developed. This software application incorporates artificial intelligence (AI) techniques and will be deployed as an interface to LET. The high burst rate (HBR) LET provides 30 GHz transmitting/20 GHz receiving (220/110 Mbps) capability for wideband communications technology experiments with the Advanced Communications Technology Satellite (ACTS). The HBR LET can monitor and evaluate the integrity of the HBR communications uplink and downlink to the ACTS satellite. The uplink HBR transmission is performed by bursting the bit-pattern as a modulated signal to the satellite. The HBR LET can determine the bit error rate (BER) under various atmospheric conditions by comparing the transmitted bit pattern with the received bit pattern. An algorithm for power augmentation will be applied to enhance the system's BER performance at reduced signal strength caused by adverse conditions.

  17. Exploiting Open Environmental Data using Linked Data and Cloud Computing: the MELODIES project

    Science.gov (United States)

    Blower, Jon; Gonçalves, Pedro; Caumont, Hervé; Koubarakis, Manolis; Perkins, Bethan

    2015-04-01

    The European Open Data Strategy establishes important new principles that ensure that European public sector data will be released at no cost (or marginal cost), in machine-readable, commonly-understood formats, and with liberal licences enabling wide reuse. These data encompass both scientific data about the environment (from Earth Observation and other fields) and other public sector information, including diverse topics such as demographics, health and crime. Many open geospatial datasets (e.g. land use) are already available through the INSPIRE directive and made available through infrastructures such as the Global Earth Observation System of Systems (GEOSS). The intention of the Open Data Strategy is to stimulate the growth of research and value-adding services that build upon these data streams; however, the potential value inherent in open data, and the benefits that can be gained by combining previously-disparate sources of information are only just starting to become understood. The MELODIES project (Maximising the Exploitation of Linked Open Data In Enterprise and Science) is developing eight innovative and sustainable services, based upon Open Data, for users in research, government, industry and the general public in a broad range of societal and environmental benefit areas. MELODIES (http://melodiesproject.eu) is a European FP7 project that is coordinated by the University of Reading and has sixteen partners (including nine SMEs) from eight European countries. It started in November 2013 and will run for three years. The project is therefore in its early stages and therefore we will value the opportunity that this workshop affords to present our plans and interact with the wider Linked Geospatial Data community. The project is developing eight new services[1] covering a range of domains including agriculture, urban ecosystems, land use management, marine information, desertification, crisis management and hydrology. These services will combine Earth

  18. Analysis of voltage modulation based active damping techniques for small DC-link drive system

    DEFF Research Database (Denmark)

    Wang, Dong; Lu, Kaiyuan; Rasmussen, Peter Omand

    2015-01-01

    Small DC-link drive system, built with film capacitor in the DC link, may have the advantages of longer lifetime and the possibility to achieve a more compact design of capacitor bank at medium and high power rates. However, it exhibits instability problem, especially when it is fed by a soft grid...

  19. The VTRx+, an optical link module for data transmission at HL-LHC

    CERN Document Server

    Troska, Jan; Detraz, Stephane; Kraxner, Andrea; Olanterä, Lauri; Scarcella, Carmelo; Sigaud, Christophe; Soos, Csaba; Vasey, Francois

    2017-01-01

    Optical data transmission will remain a key enabling technology for the upgrading detectors at HL-LHC. In particular the inner tracking detectors will require low-mass, radiation tolerant optical transmit and receive modules for tight integration in the detector front-ends. We describe the development of such a module, giving details of the design, functional and environmental performance, as well as showing the feasibility of achieving small size, low-mass, and low-power operation.

  20. Ontario: linking nursing outcomes, workload and staffing decisions in the workplace: the Dashboard Project.

    Science.gov (United States)

    Fram, Nancy; Morgan, Beverley

    2012-03-01

    Research shows that nurses want to provide more input into assessing patient acuity, changes in patient needs and staffing requirements. The Dashboard Project involved the further development and application of an electronic monitoring tool that offers a single source of nursing, patient and organizational information. It is designed to help inform nurse staffing decisions within a hospital setting. The Dashboard access link was installed in computers in eight nursing units within the Hamilton Health Sciences (HHS) network. The Dashboard indicators are populated from existing information/patient databases within the Decision Support Department at HHS. Committees composed of the unit manager, staff nurses, project coordinator, financial controller and an information controller met regularly to review the Dashboard indicators. Participants discussed the ability of the indicators to reflect their patients' needs and the feasibility of using the indicators to inform their clinical staffing plans. Project findings suggest that the Dashboard is a work in progress. Many of the indicators that had originally been incorporated were refined and will continue to be revised based on suggestions from project participants and further testing across HHS. Participants suggested the need for additional data, such as the time that nurses are off the unit (for code blue response, patient transfers and accompanying patients for tests); internal transfers/bed moves to accommodate patient-specific issues and particularly to address infection control issues; deaths and specific unit-centred data in addition to the generic indicators. The collaborative nature of the project enabled staff nurses and management to work together on a matter of high importance to both, providing valuable recommendations for shared nursing and interprofessional planning, further Dashboard development and project management.

  1. Half-cycle QAM modulation for VCSEL-based optical links

    DEFF Research Database (Denmark)

    Pham, Tien Thang; Rodes Lopez, Roberto; Jensen, Jesper Bevensee

    2012-01-01

    Abstract (40-Word Limit): Novel spectrally efficient half-cycle QAM modulation is experimentally demonstrated. 10 Gbps 4-QAM signal in 7.5-GHz bandwidth was successfully transmitted over 20 km SMF using an un-cooled 1.5 µm VCSEL with no equalization applied.......Abstract (40-Word Limit): Novel spectrally efficient half-cycle QAM modulation is experimentally demonstrated. 10 Gbps 4-QAM signal in 7.5-GHz bandwidth was successfully transmitted over 20 km SMF using an un-cooled 1.5 µm VCSEL with no equalization applied....

  2. Measurement of Chromatic Dispersion using the Baseband Radio-Frequency Response of a Phase-Modulated Analog Optical Link Employing a Reference Fiber

    National Research Council Canada - National Science Library

    McKinney, Jason D; Diehl, John

    2007-01-01

    In this work we demonstrate a new technique for measuring the chromatic dispersion of an optical fiber using the baseband RF response of a phase-modulated analog optical link in concert with a well...

  3. Impact of frequency modulation ratio on capacitor cells balancing in phase-shifted PWM based chain-link STATCOM

    DEFF Research Database (Denmark)

    Behrouzian, Ehsan; Bongiorno, Massimo; Teodorescu, Remus

    2014-01-01

    to provide more uniform power distribution among the cells, two different methods called, a) carrier swapping and b) non-integer frequency modulation ratio are studied. In particular, it is shown that the selection of a non-integer frequency modulation ratio helps in providing a more uniform power......The purpose of this paper is to investigate the impact of switching harmonics on the instantaneous power that flows in the cells of a chain-link based STATCOM when using Phase-Shifted PWM. Two different cases are investigated for the converter cells: low, and high switching frequency. It is shown...... that any deviation from the ideal conditions lead to undesired harmonics, which will impact the charge of the dc capacitors. It is also shown that for low switching frequencies, cells voltage sideband harmonics interact with baseband harmonics of the current and causes extra source of unbalance. In order...

  4. Performance evaluation and optimization of multiband phase-modulated radio over IsOWC link with balanced coherent homodyne detection

    Science.gov (United States)

    Zong, Kang; Zhu, Jiang

    2018-04-01

    In this paper, we present a multiband phase-modulated (PM) radio over intersatellite optical wireless communication (IsOWC) link with balanced coherent homodyne detection. The proposed system can provide the transparent transport of multiband radio frequency (RF) signals with higher linearity and better receiver sensitivity than intensity modulated with direct detection (IM/DD) system. The expressions of RF gain, noise figure (NF) and third-order spurious-free dynamic range (SFDR) are derived considering the third-order intermodulation product and amplifier spontaneous emission (ASE) noise. The optimal power of local oscillator (LO) optical signal is also derived theoretically. Numerical results for RF gain, NF and third-order SFDR are given for demonstration. Results indicate that the gain of the optical preamplifier and the power of LO optical signal should be optimized to obtain the satisfactory performance.

  5. Design and assembly of the optical modules for phase-2 of the NEMO project

    Energy Technology Data Exchange (ETDEWEB)

    Leonora, E., E-mail: emanuele.leonora@ct.infn.it; Aiello, S.

    2013-10-11

    The NEMO collaboration team has undertaken a Phase-2 project, which aims at the realization and installation of a new infrastructure at the Capo Passero (Italy) deep-sea site at a depth of 3500 m. With this objective in mind, a fully equipped tower with 8-storey hosting two optical modules at each end is under construction. Following a well established procedure, 32 optical modules have been assembled. The optical module consists of a large area photomultiplier tube enclosed in a pressure resistant glass sphere with a diameter of 13 in. The photomultiplier is a R7081 type, produced by Hamamatsu, with a photocathode area with a diameter of 10 in. and 10 dynodes. Mechanical and optical contacts between the front of the photomultiplier tube and the glass surface are ensured by an optical bi-component silicone gel. A mu-metal cage is used to shield the photomultiplier against the influence of the Earth's magnetic field.

  6. The research and development of module 3D designing system for nuclear power project based on the PDMS

    International Nuclear Information System (INIS)

    Lu Qinwu; Li Yi; Wu Xiangyong

    2012-01-01

    In order to meet the demand of implementing Modularization design in CPR1000 nuclear power projects, this study aims to develop, relying on CPR1000 nuclear power project, the self-reliant module 3D design system based on the PDMS. so as to offer a convenient and effective module 3D design tool for the designers. Satisfactory results have been achieved through the test and application of two design projects. The research and application have entered the domestic advanced level. (authors)

  7. Software Modules for the Proximity-1 Space Link Interleaved Time Synchronization (PITS) Protocol

    Science.gov (United States)

    Woo, Simon S.; Veregge, John R.; Gao, Jay L.; Clare, Loren P.; Mills, David

    2012-01-01

    The Proximity-1 Space Link Interleaved Time Synchronization (PITS) protocol provides time distribution and synchronization services for space systems. A software prototype implementation of the PITS algorithm has been developed that also provides the test harness to evaluate the key functionalities of PITS with simulated data source and sink. PITS integrates time synchronization functionality into the link layer of the CCSDS Proximity-1 Space Link Protocol. The software prototype implements the network packet format, data structures, and transmit- and receive-timestamp function for a time server and a client. The software also simulates the transmit and receive-time stamp exchanges via UDP (User Datagram Protocol) socket between a time server and a time client, and produces relative time offsets and delay estimates.

  8. Waste receiving and processing facility module 1 data management system software project management plan

    International Nuclear Information System (INIS)

    Clark, R.E.

    1994-01-01

    This document provides the software development plan for the Waste Receiving and Processing (WRAP) Module 1 Data Management System (DMS). The DMS is one of the plant computer systems for the new WRAP 1 facility (Project W-026). The DMS will collect, store, and report data required to certify the low level waste (LLW) and transuranic (TRU) waste items processed at WRAP 1 as acceptable for shipment, storage, or disposal

  9. Experimental demonstration of optical data links using a hybrid CAP/QAM modulation scheme.

    Science.gov (United States)

    Wei, J L; Ingham, J D; Cheng, Q; Cunningham, D G; Penty, R V; White, I H

    2014-03-15

    The first known experimental demonstrations of a 10  Gb/s hybrid CAP-2/QAM-2 and a 20  Gb/s hybrid CAP-4/QAM-4 transmitter/receiver-based optical data link are performed. Successful transmission over 4.3 km of standard single-mode fiber (SMF) is achieved, with a link power penalty ∼0.4  dBo for CAP-2/QAM-2 and ∼1.5  dBo for CAP-4/QAM-4 at BER=10(-9).

  10. 71-Mbit/s ultraviolet-B LED communication link based on 8-QAM-OFDM modulation

    KAUST Repository

    Sun, Xiaobin

    2017-09-14

    A demonstration of ultraviolet-B (UVB) communication link is implemented utilizing quadrature amplitude modulation (QAM) orthogonal frequency-division multiplexing (OFDM). The demonstration is based on a 294-nm UVB-light-emitting-diode (UVB-LED) with a full-width at half-maximum (FWHM) of 9 nm and light output power of 190 μW, at 7 V, with a special silica gel lens on top of it. A −3-dB bandwidth of 29 MHz was measured and a high-speed near-solar-blind communication link with a data rate of 71 Mbit/s was achieved using 8-QAM-OFDM at perfect alignment. 23.6 Mbit/s using 2-QAM-OFDM when the angle subtended by the pointing directions of the UVB-LED and photodetector (PD) is 12 degrees, thus establishing a diffuse-line-of-sight (LOS) link. The measured bit-error rate (BER) of 2.8 × 10−4 and 2.4 × 10−4, respectively, are well below the forward error correction (FEC) criterion of 3.8 × 10−3. The demonstrated high data-rate OFDM-based UVB communication link paves the way for realizing high-speed non-line-of-sight free-space optical communications.

  11. 71-Mbit/s ultraviolet-B LED communication link based on 8-QAM-OFDM modulation.

    Science.gov (United States)

    Sun, Xiaobin; Zhang, Zhenyu; Chaaban, Anas; Ng, Tien Khee; Shen, Chao; Chen, Rui; Yan, Jianchang; Sun, Haiding; Li, Xiaohang; Wang, Junxi; Li, Jinmin; Alouini, Mohamed-Slim; Ooi, Boon S

    2017-09-18

    A demonstration of ultraviolet-B (UVB) communication link is implemented utilizing quadrature amplitude modulation (QAM) orthogonal frequency-division multiplexing (OFDM). The demonstration is based on a 294-nm UVB-light-emitting-diode (UVB-LED) with a full-width at half-maximum (FWHM) of 9 nm and light output power of 190 μW, at 7 V, with a special silica gel lens on top of it. A -3-dB bandwidth of 29 MHz was measured and a high-speed near-solar-blind communication link with a data rate of 71 Mbit/s was achieved using 8-QAM-OFDM at perfect alignment. 23.6 Mbit/s using 2-QAM-OFDM when the angle subtended by the pointing directions of the UVB-LED and photodetector (PD) is 12 degrees, thus establishing a diffuse-line-of-sight (LOS) link. The measured bit-error rate (BER) of 2.8 ×10 -4 and 2.4 ×10 -4 , respectively, are well below the forward error correction (FEC) criterion of 3.8 ×10 -3 . The demonstrated high data-rate OFDM-based UVB communication link paves the way for realizing high-speed non-line-of-sight free-space optical communications.

  12. 71-Mbit/s ultraviolet-B LED communication link based on 8-QAM-OFDM modulation

    KAUST Repository

    Sun, Xiaobin; Zhang, Zhenyu; Chaaban, Anas; Ng, Tien Khee; Shen, Chao; Chen, Rui; Yan, Jianchang; Sun, Haiding; Li, Xiaohang; Wang, Junxi; Li, Jinmin; Alouini, Mohamed-Slim; Ooi, Boon S.

    2017-01-01

    A demonstration of ultraviolet-B (UVB) communication link is implemented utilizing quadrature amplitude modulation (QAM) orthogonal frequency-division multiplexing (OFDM). The demonstration is based on a 294-nm UVB-light-emitting-diode (UVB-LED) with a full-width at half-maximum (FWHM) of 9 nm and light output power of 190 μW, at 7 V, with a special silica gel lens on top of it. A −3-dB bandwidth of 29 MHz was measured and a high-speed near-solar-blind communication link with a data rate of 71 Mbit/s was achieved using 8-QAM-OFDM at perfect alignment. 23.6 Mbit/s using 2-QAM-OFDM when the angle subtended by the pointing directions of the UVB-LED and photodetector (PD) is 12 degrees, thus establishing a diffuse-line-of-sight (LOS) link. The measured bit-error rate (BER) of 2.8 × 10−4 and 2.4 × 10−4, respectively, are well below the forward error correction (FEC) criterion of 3.8 × 10−3. The demonstrated high data-rate OFDM-based UVB communication link paves the way for realizing high-speed non-line-of-sight free-space optical communications.

  13. Experimental 2.5 Gbit/s QPSK WDM coherent phase modulated radio-over-fibre link with digital demodulation by a K-means algorithm

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Caballero Jambrina, Antonio; Amaya Fernández, Ferney Orlando

    2009-01-01

    Highest reported bit rate of 2.5 Gbit/s for optically phase modulated radio-over-fibre link employing coherent detection is demonstrated. Demodulation of 3·2.5 Gbit/s QPSK modulated WDM channels, is achieved after 79km of transmission through deployed fiber....

  14. Development of modulation strategies for NPC converter addressing DC link voltage balancing and CMV reduction

    DEFF Research Database (Denmark)

    Boian, D.; Biris, C.; Teodorescu, Remus

    2012-01-01

    3L-NPC inverters are more popular due to their superior performance compared with two level inverters. One of the most optimal applications for multilevel inverter is the Adjustable Speed Drives (ASD). The industry reported numerous ASD failures due to high frequency PWM. Those failures consist i...... strategies is to reduce the Common Mode Voltage (CMV) and balance the DC Link Voltage....

  15. SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity.

    Science.gov (United States)

    Barker, Thomas H; Baneyx, Gretchen; Cardó-Vila, Marina; Workman, Gail A; Weaver, Matt; Menon, Priya M; Dedhar, Shoukat; Rempel, Sandra A; Arap, Wadih; Pasqualini, Renata; Vogel, Viola; Sage, E Helene

    2005-10-28

    SPARC, a 32-kDa matricellular glycoprotein, mediates interactions between cells and their extracellular matrix, and targeted deletion of Sparc results in compromised extracellular matrix in mice. Fibronectin matrix provides provisional tissue scaffolding during development and wound healing and is essential for the stabilization of mature extracellular matrix. Herein, we report that SPARC expression does not significantly affect fibronectin-induced cell spreading but enhances fibronectin-induced stress fiber formation and cell-mediated partial unfolding of fibronectin molecules, an essential process in fibronectin matrix assembly. By phage display, we identify integrin-linked kinase as a potential binding partner of SPARC and verify the interaction by co-immunoprecipitation and colocalization in vitro. Cells lacking SPARC exhibit diminished fibronectin-induced integrin-linked kinase activation and integrin-linked kinase-dependent cell-contractile signaling. Furthermore, induced expression of SPARC in SPARC-null fibroblasts restores fibronectin-induced integrin-linked kinase activation, downstream signaling, and fibronectin unfolding. These data further confirm the function of SPARC in extracellular matrix organization and identify a novel mechanism by which SPARC regulates extracellular matrix assembly.

  16. THz photonic wireless links with 16-QAM modulation in the 375-450 GHz band

    DEFF Research Database (Denmark)

    Jia, Shi; Yu, Xianbin; Hu, Hao

    2016-01-01

    forward error correction (HD-FEC) threshold of 3.8e-3 with 7% overhead. In addition, we also successfully demonstrate hybrid photonic wireless transmission of 40 Gbit/s 16-QAM signal at carrier frequencies of 400 GHz and 425 GHz over 30 km standard single mode fiber (SSMF) between the optical baseband...... signal transmitter and the THz wireless transmitter with negligible induced power penalty.......We propose and experimentally demonstrate THz photonic wireless communication systems with 16-QAM modulation in the 375-450 GHz band. The overall throughput reaches as high as 80 Gbit/s by exploiting four THz channels with 5 Gbaud 16-QAM baseband modulation per channel. We create a coherent optical...

  17. Development and Evaluation of an On-Line Educational Module for Volunteer Leaders on Bio-Security in Washington State 4-H Livestock Projects

    Science.gov (United States)

    Stevenson, Jill L.; Moore, Dale A.; Newman, Jerry; Schmidt, Janet L.; Smith, Sarah M.; Smith, Jean; Kerr, Susan; Wallace, Michael; BoyEs, Pat

    2011-01-01

    An on-line module on disease prevention was created for 4-H volunteer leaders who work with livestock projects in Washington to better prepare them to teach youth about bio-security and its importance in 4-H livestock projects. Evaluation of the module and usage statistics since the module's debut were collected and evaluated. The module increases…

  18. Atypical Modulations of N170 Component during Emotional Processing and Their Links to Social Behaviors in Ex-combatants.

    Science.gov (United States)

    Trujillo, Sandra P; Valencia, Stella; Trujillo, Natalia; Ugarriza, Juan E; Rodríguez, Mónica V; Rendón, Jorge; Pineda, David A; López, José D; Ibañez, Agustín; Parra, Mario A

    2017-01-01

    Emotional processing (EP) is crucial for the elaboration and implementation of adaptive social strategies. EP is also necessary for the expression of social cognition and behavior (SCB) patterns. It is well-known that war contexts induce socio-emotional atypical functioning, in particular for those who participate in combats. Thus, ex-combatants represent an ideal non-clinical population to explore EP modulation and to evaluate its relation with SCB. The aim of this study was to explore EP and its relation with SCB dimensions such as empathy, theory of mind and social skills in a sample of 50 subjects, of which 30 were ex-combatants from illegally armed groups in Colombia, and 20 controls without combat experience. We adapted an Emotional Recognition Task for faces and words and synchronized it with electroencephalographic recording. Ex-combatants presented with higher assertion skills and showed more pronounced brain responses to faces than Controls. They did not show the bias toward anger observed in control participants whereby the latter group was more likely to misclassify neutral faces as angry. However, ex-combatants showed an atypical word valence processing. That is, words with different emotions yielded no differences in N170 modulations. SCB variables were successfully predicted by neurocognitive variables. Our results suggest that in ex-combatants the links between EP and SCB functions are reorganized. This may reflect neurocognitive modulations associated to chronic exposure to war experiences.

  19. Atypical Modulations of N170 Component during Emotional Processing and Their Links to Social Behaviors in Ex-combatants

    Directory of Open Access Journals (Sweden)

    Sandra P. Trujillo

    2017-05-01

    Full Text Available Emotional processing (EP is crucial for the elaboration and implementation of adaptive social strategies. EP is also necessary for the expression of social cognition and behavior (SCB patterns. It is well-known that war contexts induce socio-emotional atypical functioning, in particular for those who participate in combats. Thus, ex-combatants represent an ideal non-clinical population to explore EP modulation and to evaluate its relation with SCB. The aim of this study was to explore EP and its relation with SCB dimensions such as empathy, theory of mind and social skills in a sample of 50 subjects, of which 30 were ex-combatants from illegally armed groups in Colombia, and 20 controls without combat experience. We adapted an Emotional Recognition Task for faces and words and synchronized it with electroencephalographic recording. Ex-combatants presented with higher assertion skills and showed more pronounced brain responses to faces than Controls. They did not show the bias toward anger observed in control participants whereby the latter group was more likely to misclassify neutral faces as angry. However, ex-combatants showed an atypical word valence processing. That is, words with different emotions yielded no differences in N170 modulations. SCB variables were successfully predicted by neurocognitive variables. Our results suggest that in ex-combatants the links between EP and SCB functions are reorganized. This may reflect neurocognitive modulations associated to chronic exposure to war experiences.

  20. The data module, the missing link in high level control languages

    International Nuclear Information System (INIS)

    Crowley-Milling, M.C.

    1979-01-01

    In order to be able to use the full power and simplicity of a high level language for writing plant control programs, it must be possible to use the plant variables in the same manner as program variables, completely transparent to the address structure of the hardware and interface. Some of the high level languages provide facilities for writing procedures or subroutines to make this possible. However, most of the facilities provided share a number of disadvantages: they are usually relatively complicated for the user, involving passing many parameters which the programmer has to specify at each call; they usually have restrictions on the data types that can be used, and the data bases are normally organised to suit the interface system. However, the high level programmer is interested in the equipment to be controlled such as motors, pumps, power supplies, valves, etc., rather than the means of interfacing the equipment, and it greatly simplifies his task if he can call for actions on these items, using simple mnemonic names and a simple format. The design of the control system for the CERN 400 GeV proton accelerator, using a network of some thirty computers, provided the opportunity to try out a different approach, using an interpreter for the high-level control language NODAL, together with special functions which are called 'data modules'. The use of the data module and interpreter are described. (author)

  1. Analytical formulation of directly modulated OOFDM signals transmitted over an IM/DD dispersive link.

    Science.gov (United States)

    Sánchez, C; Ortega, B; Wei, J L; Tang, J; Capmany, J

    2013-03-25

    We provide an analytical study on the propagation effects of a directly modulated OOFDM signal through a dispersive fiber and subsequent photo-detection. The analysis includes the effects of the laser operation point and the interplay between chromatic dispersion and laser chirp. The final expression allows to understand the physics behind the transmission of a multi-carrier signal in the presence of residual frequency modulation and the description of the induced intermodulation distortion gives us a detailed insight into the diferent intermodulation products which impair the recovered signal at the receiver-end side. Numerical comparisons between transmission simulations results and those provided by evaluating the expression obtained are carried out for different laser operation points. Results obtained by changing the fiber length, laser parameters and using single mode fiber with negative and positive dispersion are calculated in order to demonstrate the validity and versatility of the theory provided in this paper. Therefore, a novel analytical formulation is presented as a versatile tool for the description and study of IM/DD OOFDM systems with variable design parameters.

  2. BIM-Based 4D Simulation to Improve Module Manufacturing Productivity for Sustainable Building Projects

    Directory of Open Access Journals (Sweden)

    Joosung Lee

    2017-03-01

    Full Text Available Modular construction methods, where products are manufactured beforehand in a factory and then transported to the site for installation, are becoming increasingly popular for construction projects in many countries as this method facilitates the use of the advanced technologies that support sustainability in building projects. This approach requires dual factory–site process management to be carefully coordinated and the factory module manufacturing process must therefore be managed in a detailed and quantitative manner. However, currently, the limited algorithms available to support this process are based on mathematical methodologies that do not consider the complex mix of equipment, factories, personnel, and materials involved. This paper presents three new building information modeling-based 4D simulation frameworks to manage the three elements—process, quantity, and quality—that determine the productivity of factory module manufacturing. These frameworks leverage the advantages of 4D simulation and provide more precise information than existing conventional documents. By utilizing a 4D model that facilitates the visualization of a wide range of data variables, manufacturers can plan the module manufacturing process in detail and fully understand the material, equipment, and workflow needed to accomplish the manufacturing tasks. Managers can also access information about material quantities for each process and use this information for earned value management, warehousing/storage, fabrication, and assembly planning. By having a 4D view that connects 2D drawing models, manufacturing errors and rework can be minimized and problems such as construction delays, quality lapses, and cost overruns vastly reduced.

  3. Exploring protein structure and dynamics through a project-oriented biochemistry laboratory module.

    Science.gov (United States)

    Lipchock, James M; Ginther, Patrick S; Douglas, Bonnie B; Bird, Kelly E; Patrick Loria, J

    2017-09-01

    Here, we present a 10-week project-oriented laboratory module designed to provide a course-based undergraduate research experience in biochemistry that emphasizes the importance of biomolecular structure and dynamics in enzyme function. This module explores the impact of mutagenesis on an important active site loop for a biomedically-relevant human enzyme, protein tyrosine phosphatase 1B (PTP1B). Over the course of the semester students guide their own mutant of PTP1B from conception to characterization in a cost-effective manner and gain exposure to fundamental techniques in biochemistry, including site-directed DNA mutagenesis, bacterial recombinant protein expression, affinity column purification, protein quantitation, SDS-PAGE, and enzyme kinetics. This project-based approach allows an instructor to simulate a research setting and prepare students for productive research beyond the classroom. Potential modifications to expand or contract this module are also provided. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):403-410, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

  4. Modulation of type II TGF-β receptor degradation by integrin-linked kinase.

    Science.gov (United States)

    Vi, Linda; Boo, Stellar; Sayedyahossein, Samar; Singh, Randeep K; McLean, Sarah; Di Guglielmo, Gianni M; Dagnino, Lina

    2015-03-01

    Cutaneous responses to injury, infection, and tumor formation involve the activation of resident dermal fibroblasts and subsequent transition to myofibroblasts. The key for induction of myofibroblast differentiation is the activation of transforming growth factor-β (TGF-β) receptors and stimulation of integrins and their associated proteins, including integrin-linked kinase (ILK). Cross-talk processes between TGF-β and ILK are crucial for myofibroblast formation, as ILK-deficient dermal fibroblasts exhibit impaired responses to TGF-β receptor stimulation. We now show that ILK associates with type II TGF-β receptors (TβRII) in ligand- and receptor kinase activity-independent manners. In cells with targeted Ilk gene inactivation, cellular levels of TβRII are decreased, through mechanisms that involve enhanced ubiquitination and proteasomal degradation. Partitioning of TGF-β receptors into membrane has been linked to proteasome-dependent receptor degradation. We found that interfering with membrane raft formation in ILK-deficient cells restored TβRII levels and signaling. These observations support a model whereby ILK functions in fibroblasts to direct TβRII away from degradative pathways during their differentiation into myofibroblasts.

  5. Happiness cools the glow of familiarity: Psychophysiological evidence that mood modulates the familiarity-affect link

    Science.gov (United States)

    de Vries, Marieke; Holland, Rob W.; Chenier, Troy; Starr, Mark J.; Winkielman, Piotr

    2010-01-01

    People often prefer familiar stimuli, presumably because familiarity signals safety. This preference can occur with merely repeated “old” stimuli, but it is most robust with “new” but highly familiar prototypes of a known category (beauty-in-averages effect). However, is familiarity always warm? Tuning accounts of mood hold that positive mood signals a safe environment whereas negative mood signals an unsafe environment. Thus, the value of familiarity should depend on mood. We show that compared to a sad mood, a happy mood eliminates the preference for familiar stimuli, as shown in measures of self-reported liking and physiological measures of affect (EMG indicator of spontaneous smiling). The basic effect of exposure on preference and its modulation by mood were most robust on prototypes (category averages). All this occurs even though prototypes might be more familiar in a happy mood. We conclude that mood changes the hedonic implications of familiarity cues. PMID:20424063

  6. Design and mass production of the optical modules for KM3NeT-Italia project

    Directory of Open Access Journals (Sweden)

    Leonora Emanuele

    2016-01-01

    Full Text Available The KM3NeT European project aims at constructing a km3 underwater neutrino telescope in the depths of the Mediterranean Sea. The first phase that is under construction will comprise eight tower-like detection structures (KM3NeT-Italia, which will form the internal core of a km3-scale detector. The detection element of KM3NeT-Italia, the optical module, is made of a 13-inch pressure-resistant glass-vessel that contains a single 10-inch photomultiplier and the relative electronics. The design of the whole optical module, the main results obtained from the massive photomultipliers measurements, and the foremost phases of the mass production procedure performed at the production site of Catania are also presented.

  7. FixO3 project results, legacy and module migration to EMSO

    Science.gov (United States)

    Lampitt, Richard

    2017-04-01

    The fixed point open ocean observatory network (FixO3) project is an international project aimed at integrating in a single network all fixed point open ocean observatories operated by European organisations and to harmonise and coordinate technological, procedural and data management across the stations. The project is running for four years since September 2013 with 29 partners across Europe and a budget of 7M Euros and is now coming to its final phase. In contrast to several past programmes, the opportunity has arisen to ensure that many of the project achievements can migrate into the newly formed European Multidisciplinary Seafloor and water column Observatory (EMSO) research infrastructure. The final phase of the project will focus on developing a strategy to transfer the results in an efficient way to maintain their relevance and maximise their use. In this presentation, we will highlight the significant achievements of FixO3 over the past three years focussing on the modules which will be transferred to EMSO in the coming 9 months. These include: 1. Handbook of best practices for operating fixed point observatories 2. Metadata catalogue 3. Earth Virtual Observatory (EarthVO) for data visualisation and comparison 4. Open Ocean Observatory Yellow Pages (O3YP) 5. Training material for hardware, data and data products used

  8. Linking models of human behaviour and climate alters projected climate change

    Science.gov (United States)

    Beckage, Brian; Gross, Louis J.; Lacasse, Katherine; Carr, Eric; Metcalf, Sara S.; Winter, Jonathan M.; Howe, Peter D.; Fefferman, Nina; Franck, Travis; Zia, Asim; Kinzig, Ann; Hoffman, Forrest M.

    2018-01-01

    Although not considered in climate models, perceived risk stemming from extreme climate events may induce behavioural changes that alter greenhouse gas emissions. Here, we link the C-ROADS climate model to a social model of behavioural change to examine how interactions between perceived risk and emissions behaviour influence projected climate change. Our coupled climate and social model resulted in a global temperature change ranging from 3.4-6.2 °C by 2100 compared with 4.9 °C for the C-ROADS model alone, and led to behavioural uncertainty that was of a similar magnitude to physical uncertainty (2.8 °C versus 3.5 °C). Model components with the largest influence on temperature were the functional form of response to extreme events, interaction of perceived behavioural control with perceived social norms, and behaviours leading to sustained emissions reductions. Our results suggest that policies emphasizing the appropriate attribution of extreme events to climate change and infrastructural mitigation may reduce climate change the most.

  9. Waste Receiving and Processing Facility, Module 1: Volume 7, Project design criteria

    International Nuclear Information System (INIS)

    1992-03-01

    This Project Design Criteria document for the WRAP facility at the Hanford Site is presented within a systems format. The WRAP Module 1 facility has been categorized into eight (8) engineering systems for design purposes. These systems include: receiving, shipping and storage, nondestructive assay/nondestructive examination (NDA/NDE), waste process, internal transportation, building, heating ventilation and air conditioning (HVAC), process control, and utilities. Within each system section of this document, the system-specific requirements are identified. The scope of the system is defined, the design goals are identified and the functional requirements are detailed

  10. Modulation of isochronous movements in a flexible environment: links between motion and auditory experience.

    Science.gov (United States)

    Bravi, Riccardo; Del Tongo, Claudia; Cohen, Erez James; Dalle Mura, Gabriele; Tognetti, Alessandro; Minciacchi, Diego

    2014-06-01

    The ability to perform isochronous movements while listening to a rhythmic auditory stimulus requires a flexible process that integrates timing information with movement. Here, we explored how non-temporal and temporal characteristics of an auditory stimulus (presence, interval occupancy, and tempo) affect motor performance. These characteristics were chosen on the basis of their ability to modulate the precision and accuracy of synchronized movements. Subjects have participated in sessions in which they performed sets of repeated isochronous wrist's flexion-extensions under various conditions. The conditions were chosen on the basis of the defined characteristics. Kinematic parameters were evaluated during each session, and temporal parameters were analyzed. In order to study the effects of the auditory stimulus, we have minimized all other sensory information that could interfere with its perception or affect the performance of repeated isochronous movements. The present study shows that the distinct characteristics of an auditory stimulus significantly influence isochronous movements by altering their duration. Results provide evidence for an adaptable control of timing in the audio-motor coupling for isochronous movements. This flexibility would make plausible the use of different encoding strategies to adapt audio-motor coupling for specific tasks.

  11. Controlling adsorption and passivation properties of bovine serum albumin on silica surfaces by ionic strength modulation and cross-linking.

    Science.gov (United States)

    Park, Jae Hyeon; Sut, Tun Naw; Jackman, Joshua A; Ferhan, Abdul Rahim; Yoon, Bo Kyeong; Cho, Nam-Joon

    2017-03-29

    Understanding the physicochemical factors that influence protein adsorption onto solid supports holds wide relevance for fundamental insights into protein structure and function as well as for applications such as surface passivation. Ionic strength is a key parameter that influences protein adsorption, although how its modulation might be utilized to prepare well-coated protein adlayers remains to be explored. Herein, we investigated how ionic strength can be utilized to control the adsorption and passivation properties of bovine serum albumin (BSA) on silica surfaces. As protein stability in solution can influence adsorption kinetics, the size distribution and secondary structure of proteins in solution were first characterized by dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), and circular dichroism (CD) spectroscopy. A non-monotonic correlation between ionic strength and protein aggregation was observed and attributed to colloidal agglomeration, while the primarily α-helical character of the protein in solution was maintained in all cases. Quartz crystal microbalance-dissipation (QCM-D) experiments were then conducted in order to track protein adsorption onto silica surfaces as a function of ionic strength, and the measurement responses indicated that total protein uptake at saturation coverage is lower with increasing ionic strength. In turn, the QCM-D data and the corresponding Voigt-Voinova model analysis support that the surface area per bound protein molecule is greater with increasing ionic strength. While higher protein uptake under lower ionic strengths by itself did not result in greater surface passivation under subsequent physiologically relevant conditions, the treatment of adsorbed protein layers with a gluteraldehyde cross-linking agent stabilized the bound protein in this case and significantly improved surface passivation. Collectively, our findings demonstrate that ionic strength modulation influences BSA adsorption

  12. Sox4 Links Tumor Suppression to Accelerated Aging in Mice by Modulating Stem Cell Activation

    Directory of Open Access Journals (Sweden)

    Miguel Foronda

    2014-07-01

    Full Text Available Sox4 expression is restricted in mammals to embryonic structures and some adult tissues, such as lymphoid organs, pancreas, intestine, and skin. During embryogenesis, Sox4 regulates mesenchymal and neural progenitor survival, as well as lymphocyte and myeloid differentiation, and contributes to pancreas, bone, and heart development. Aberrant Sox4 expression is linked to malignant transformation and metastasis in several types of cancer. To understand the role of Sox4 in the adult organism, we first generated mice with reduced whole-body Sox4 expression. These mice display accelerated aging and reduced cancer incidence. To specifically address a role for Sox4 in adult stem cells, we conditionally deleted Sox4 (Sox4cKO in stratified epithelia. Sox4cKO mice show increased skin stem cell quiescence and resistance to chemical carcinogenesis concomitantly with downregulation of cell cycle, DNA repair, and activated hair follicle stem cell pathways. Altogether, these findings highlight the importance of Sox4 in regulating adult tissue homeostasis and cancer.

  13. Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF)

    Energy Technology Data Exchange (ETDEWEB)

    Serrano, Isabel; Diez-Marques, Maria L.; Rodriguez-Puyol, Manuel [Department of Physiology, University of Alcala, Alcala de Henares, Madrid (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Instituto Reina Sofia de Investigacion Nefrologica (Spain); Herrero-Fresneda, Inmaculada [Nephrology Unit, IDIBELL, Hospital de Bellvitge, Barcelona (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Garcia del Moral, Raimundo [Department of Pathology, University of Granada (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Dedhar, Shoukat [Department of Integrative Oncology, BC Cancer Research Center, Vancouver, BC (Canada); Ruiz-Torres, Maria P., E-mail: mpiedad.ruiz@uah.es [Department of Physiology, University of Alcala, Alcala de Henares, Madrid (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Instituto Reina Sofia de Investigacion Nefrologica (Spain); Rodriguez-Puyol, Diego [Nephrology Unit, Hospital Universitario Principe de Asturias, Alcala de Henares, Madrid (Spain); Red de Investigacion Renal Cooperativa (RedinRen) (Spain); Instituto Reina Sofia de Investigacion Nefrologica (Spain)

    2012-11-15

    Integrin-linked kinase (ILK) is an intracellular effector of cell-matrix interactions and regulates many cellular processes, including growth, proliferation, survival, differentiation, migration, invasion and angiogenesis. The present work analyzes the role of ILK in wound healing in adult animals using a conditional knock-out of the ILK gene generated with the tamoxifen-inducible Cre-lox system (CRE-LOX mice). Results show that ILK deficiency leads to retarded wound closure in skin. Intracellular mechanisms involved in this process were analyzed in cultured mouse embryonic fibroblast (MEF) isolated from CRE-LOX mice and revealed that wounding promotes rapid activation of phosphatidylinositol 3-kinase (PI3K) and ILK. Knockdown of ILK resulted in a retarded wound closure due to a decrease in cellular proliferation and loss of HGF protein expression during the healing process, in vitro and in vivo. Alterations in cell proliferation and wound closure in ILK-deficient MEF or mice could be rescued by exogenous administration of human HGF. These data demonstrate, for the first time, that the activation of PI3K and ILK after skin wounding are critical for HGF-dependent tissue repair and wound healing. -- Highlights: Black-Right-Pointing-Pointer ILK deletion results in decreased HGF expression and delayed scratch wound repair. Black-Right-Pointing-Pointer PI3K/ILK/AKT pathway signals through HGF to regulate wound healing. Black-Right-Pointing-Pointer An ILK-dependent increase in HGF expression is responsible for wound healing in vivo. Black-Right-Pointing-Pointer ILK-KO mice are used to confirm the requirement for ILK function in wound healing. Black-Right-Pointing-Pointer Human HGF treatment restores delayed wound closure in vitro and in vivo.

  14. Construction and characterization of the detection modules for the Muon Portal Project

    Energy Technology Data Exchange (ETDEWEB)

    Blancato, A.A.; Bonanno, D.L.; La Rocca, P.; Longhitano, F.; Lo Presti, D.; Parasole, O.; Pugliatti, C.; Riggi, F.; Russo, G.V.; Santagati, G. [Dipartimento di Fisica e Astronomia, Universita di Catania and INFN, Catania, (Italy); Bandieramonte, M.; Billotta, S.; Bonanno, G.; Garozzo, S.; Marano, D.; Riggi, S.; Romeo, G. [INAF, Osservatorio Astrofisico di Catania, (Italy); Fallica, P.G.; Romeo, M. [STMicroelectronics, Catania, (Italy)

    2015-07-01

    The Muon Portal Project is a joint initiative between research and industrial partners, aimed at the construction of a real size detector prototype (6 x 3 x 7 m{sup 3}) for the inspection of containers by the muon scattering technique, devised to search for hidden high-Z fissile materials and provide a full 3D tomography of the interior of the container in a scanning time of the order of minutes. The muon tracking detector is based on a set of 48 detection modules (size 1 m x 3 m), each built with 100 extruded scintillator strips, so as to provide four X-Y detection planes, two placed above and two below the container to be inspected. Two wavelength shifting (WLS) fibres embedded in each strip convey the emitted photons to Silicon Photomultipliers (SiPM) which act as photo-sensors. After a research and development phase, which led to the choice and test of the individual components, the construction of the full size detector has already started. The paper describes the results of the mass characterization of the photo-sensors and the construction and test measurements of the first detection modules of the Project. (authors)

  15. Effect of Localizer Radiography Projection on Organ Dose at Chest CT with Automatic Tube Current Modulation.

    Science.gov (United States)

    Saltybaeva, Natalia; Krauss, Andreas; Alkadhi, Hatem

    2017-03-01

    Purpose To calculate the effect of localizer radiography projections to the total radiation dose, including both the dose from localizer radiography and that from subsequent chest computed tomography (CT) with tube current modulation (TCM). Materials and Methods An anthropomorphic phantom was scanned with 192-section CT without and with differently sized breast attachments. Chest CT with TCM was performed after one localizer radiographic examination with anteroposterior (AP) or posteroanterior (PA) projections. Dose distributions were obtained by means of Monte Carlo simulations based on acquired CT data. For Monte Carlo simulations of localizer radiography, the tube position was fixed at 0° and 180°; for chest CT, a spiral trajectory with TCM was used. The effect of tube start angles on dose distribution was investigated with Monte Carlo simulations by using TCM curves with fixed start angles (0°, 90°, and 180°). Total doses for lungs, heart, and breast were calculated as the sum of the dose from localizer radiography and CT. Image noise was defined as the standard deviation of attenuation measured in 14 circular regions of interest. The Wilcoxon signed rank test, paired t test, and Friedman analysis of variance were conducted to evaluate differences in noise, TCM curves, and organ doses, respectively. Results Organ doses from localizer radiography were lower when using a PA instead of an AP projection (P = .005). The use of a PA projection resulted in higher TCM values for chest CT (P chest CT. © RSNA, 2016 Online supplemental material is available for this article.

  16. Linking project-based production and project management temporary systems in multiple contexts : An introduction to the special edition

    NARCIS (Netherlands)

    Oerlemans, L.A.G.; Pretorius, M.W.

    2014-01-01

    As organisations in more and more industries look for flexible ways of production in the wake of rapidly changing market environments, project-based organising is becoming an increasingly important mode of organisation (Eisenhardt & Tabrizi, 1995). Whereas project-based organisation was

  17. Linking project-based production and project management temporary systems in multiple contexts: An introduction to the special edition

    Directory of Open Access Journals (Sweden)

    Leon AG Oerlemans

    2014-02-01

    Full Text Available As organisations in more and more industries look for flexible ways of production in the wake of rapidly changing market environments, project-based organising is becoming an increasingly important mode of organisation (Eisenhardt & Tabrizi, 1995. Whereas project-based organisation was traditionally mainly the domain of industries such as film making (Sorenson & Waguespack, 2006, theatre (Goodman & Goodman, 1976, and construction (Gann & Salter, 2000, a project-based mode of operation has recently pervaded many other sectors in the economy, including software development, advertising, biotechnology, consulting, emergency response, fashion, television and complex products and systems (Grabher, 2004; Hobday, 2000. This increasing prevalence is reflected in an exponentially growing body of research (Bakker, 2010, which has made marked progress in areas such as project-based learning (Prencipe & Tell, 2001, project-based innovation (Eisenhardt & Tabrizi, 1995 and project-based careers (Jones, 1996. As a consequence, research on project organisation has moved from being a narrow specialty domain toward being a broad research paradigm, attending to a broad audience in organisation science and beyond (Sydow et al., 2004. In a fairly recent review paper, Bakker (2010 shows that in the period 1988–2008 scholarly attention, as indicated by publications in books and ISI-indexed journals, grew exponentially (see Figure 1. Comparing the number of publications in the period 1988-1998 with the period 1998–2008, he observed an increase of almost 340%.

  18. Functions and requirements for Project W-236B, Initial Pretreatment Module: Revision 1

    International Nuclear Information System (INIS)

    Swanson, L.M.

    1994-01-01

    Hanford Site tank waste supernatants will be pretreated to separate the low-level and high-level fractions. The low-level waste fraction, containing the bulk of the chemical constituents, must be processed into a vitrified waste product which will be disposed of onsite, in a safe, environmentally sound, and cost effective manner. The high-level waste fraction separated during supernatant pretreatment (primarily cesium) will be recombined with an additional high-level waste fraction generated from pretreatment of the tank waste sludges and solids. This combined high-level waste fraction will be immobilized as glass and disposed in a geological repository. The purpose of this document is to establish the functional requirements baseline for Project W-236B, Initial Pretreatment Module, by defining the level 5 and 6 functions and requirements for the project. A functional analysis approach has been used to break down the program functions and associated physical requirements that each function must meet. As the systems engineering process evolves, the design requirements document will replace this preliminary functions and requirements document. The design requirements document (DRD) will identify key decisions and associated uncertainties that impact the project. A revision of this document to a DRD is not expected to change the performance requirements or open issues. However, additional requirements and issues may be identified

  19. Linking Theory with Practice: Undergraduate Project Management with School-Age Children.

    Science.gov (United States)

    Falkenberg, Loren; Russell, Randy; Ricker, Lynne

    2000-01-01

    Management students taught basic business concepts to sixth graders and managed business projects with them. The management students applied knowledge of marketing, human resources, and operations management and developed reflective learning skills through project reports and coaching sessions. (SK)

  20. Preliminary design requirements document (DRD) for Project W-236B, ''Initial Pretreatment Module''

    International Nuclear Information System (INIS)

    Swanson, L.M.

    1995-01-01

    The scope of this Design Requirements Document (DRD) is to identify and define the functions, with associated requirements, which must be performed to separate Hanford Site tank waste supernatants into low-level and high-level fractions. This documents sets forth function requirements, performance requirements, and design constraints necessary to begin conceptual design for the Initial Pretreatment Module (IPM). System and physical interfaces between the IPM project and the Tank Waste Remediation System (TWRS) are identified. The constraints, performance requirements, and transfer of information and data across a technical interface will be documented in an Interface Control Document. Supplemental DRDs will be prepared to provide more detailed requirements specific to systems described in the DRD

  1. Asymptotic sequences over ideals and projectively equivalent ideals with respect to modules

    International Nuclear Information System (INIS)

    Naghipour, R.; Sedghi, M.

    2007-09-01

    Let R be a commutative Noetherian ring, and let N be a non-zero finitely generated R-module. The purpose of this paper is to show that if I and J are projectively equivalent ideals w.r.t. N, then a sequence x := x 1 , . . . , x n of elements of R is an asymptotic sequence over I w.r.t. N if and only if it is an asymptotic sequence over J w.r.t. N. Also, it is shown that if R is local, then the lengths of all maximal asymptotic sequences over an ideal I w.r.t. N are the same. As a consequence we derive a generalization of Rees' theorem. (author)

  2. Educational Project Management Instructional System. Module Two. Project Management Basic Principles. Volume I--Lessons 1 to 6. Volume II--Lessons 7 to 12. Volume III--Case Simulation.

    Science.gov (United States)

    Cummings, C. Peter; Cook, Desmond L.

    This module is the second in a self-instructional program designed to train public school personnel in how to manage educational projects. The purpose of this module is to provide current or potential project directors with the basic knowledge, skills, abilities, and sensitivities needed to manage a local educational project. In the areas of…

  3. ORIGEN-based Nuclear Fuel Inventory Module for Fuel Cycle Assessment: Final Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Skutnik, Steven E. [Univ. of Tennessee, Knoxville, TN (United States). Dept. of Nuclear Engineering

    2017-06-19

    The goal of this project, “ORIGEN-based Nuclear Fuel Depletion Module for Fuel Cycle Assessment" is to create a physics-based reactor depletion and decay module for the Cyclus nuclear fuel cycle simulator in order to assess nuclear fuel inventories over a broad space of reactor operating conditions. The overall goal of this approach is to facilitate evaluations of nuclear fuel inventories for a broad space of scenarios, including extended used nuclear fuel storage and cascading impacts on fuel cycle options such as actinide recovery in used nuclear fuel, particularly for multiple recycle scenarios. The advantages of a physics-based approach (compared to a recipe-based approach which has been typically employed for fuel cycle simulators) is in its inherent flexibility; such an approach can more readily accommodate the broad space of potential isotopic vectors that may be encountered under advanced fuel cycle options. In order to develop this flexible reactor analysis capability, we are leveraging the Origen nuclear fuel depletion and decay module from SCALE to produce a standalone “depletion engine” which will serve as the kernel of a Cyclus-based reactor analysis module. The ORIGEN depletion module is a rigorously benchmarked and extensively validated tool for nuclear fuel analysis and thus its incorporation into the Cyclus framework can bring these capabilities to bear on the problem of evaluating long-term impacts of fuel cycle option choices on relevant metrics of interest, including materials inventories and availability (for multiple recycle scenarios), long-term waste management and repository impacts, etc. Developing this Origen-based analysis capability for Cyclus requires the refinement of the Origen analysis sequence to the point where it can reasonably be compiled as a standalone sequence outside of SCALE; i.e., wherein all of the computational aspects of Origen (including reactor cross-section library processing and interpolation, input and output

  4. Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project.

    Science.gov (United States)

    Cannon-Albright, Lisa A; Dintelman, Sue; Maness, Tim; Backus, Steve; Thomas, Alun; Meyer, Laurence J

    2013-07-01

    Creation of a genealogy of the United States and its ancestral populations is under way. When complete, this US genealogy will be record linked to the National Veteran's Health Administration medical data representing more than 8 million US veterans. Genealogical data are gathered from public sources, primarily the Internet. Record linking using data from relatives is accomplished to integrate multiple data sources and then to link genealogical data to the veteran's demographic data. This resource currently includes genealogy for more than 22 million individuals representing the Intermountain West and the East Coast. The demographic data for more than 40,000 veteran patients using Veterans Hospital Administration services in Utah and Massachusetts have already been record linked. The resource is only in its second year of creation and already represents the largest such combination of genealogy and medical data in the world. The data sources, the creation of the genealogy, record-linking methods and results, proposed genetic analyses, and future directions are discussed.

  5. PROJECT MANAGEMENT OFFICE – LINK BETWEEN ORGANIZATIONAL STRATEGIC AND OPERATIONAL: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Mario Manzini Cianfanelli

    2014-12-01

    Full Text Available The objective of this work is to demonstrate the organizational integration achieved through the implementation of a project management office (PMO, created to combat the loss of water distribution in one of the business units of Basic Sanitation Company of the State of São Paulo – Sabesp. The methodology used to achieve this goal was the study of a single case in which the information was obtained through documentary research and semi-structured interviews. The results showed how this integration was achieved with the adoption of a standard methodology in project management, control based on information technology and the spread of the organization's strategy in the sectors below. This work concluded that with this implantation of the project management office it was possible to improve the planning and the control of the activities of the projects through a pattern methodology in managing projects that gave possibilities to create a new culture focusing in solving problems.

  6. Linking Mitigation and Adaptation in Carbon Forestry Projects: Evidence from Belize

    DEFF Research Database (Denmark)

    Kongsager, Rico; Corbera, Esteve

    2015-01-01

    that linking mitigation and adaptation has not been possible, because the mandate of forest carbon markets does not incorporate adaptation concerns. The projects’ contribution to forest ecosystems’ adaptation, for instance, by reducing human encroachments and by increasing ecosystem connectivity, has been...... instead to promote more holistic and territorial-based approaches targeting both mitigation and adaptation goals....

  7. Study of an accelerating superconducting module and its feedback loop systems for the MYRRHA project

    International Nuclear Information System (INIS)

    Bouly, F.

    2011-11-01

    The MYRRHA ( Multi-purpose hybrid Research Reactor for High-tech Applications ) project aims at constructing an accelerator driven system (ADS) demonstrator (50 a 100 MWth) to explore the feasibility of nuclear waste transmutation. Such a subcritical reactor requires an extremely reliable accelerator which delivers a CW high power protons beam (600 MeV, 4 mA). The reference solution for this machine is a superconducting linear accelerator. This thesis presents the work - undertaken at IPN Orsay in October 2008 - on the study of a prototypical superconducting module and the feedback control systems of its cavity for the high energy part of the MYRRHA linac. First, the optimization and the design of 5-cell elliptical cavities (β=0,65), operating at 704.4 MHz, are presented. Then, the experimental work focuses on a reliability oriented study of the 'cryo-module' which hold a prototypical 5-cell cavity (β=0,47). In this study, the dynamic behavior of the fast tuning system of the cavity was measured and qualified. The 'field flatness' issue in 'low beta' multi-cell cavity was also brought to light. Finally, a fault-tolerance analysis of the linac was carried out. Toward this goal, a model of the cavity, its RF feedback loop system and its tuning system feedback loop was developed. This study enabled to determine the RF power needs, the tuning system requirements and as well as to demonstrate the feasibility of fast fault-recovery scenarios to minimize the number of beam interruptions in the MYRRHA linac. (author)

  8. Socio-Economical, Environmental Evaluation of Ken-Betwa River Link Project, India

    OpenAIRE

    Pathak Hemant

    2016-01-01

    The India's ambitious Rs 9,393 crore Ken-Betwa river interlinking project will impact very significantly on Socio-economic life of two million people of Bundelkhand region, India. Water is an important input for survival and sustenance of life. The demand of this natural gift has been increasing exponentially. This ambitious project will help us in irrigation, potable water, cheap transportation, electricity as well as a source of livelihood for our ever increasing population. In Bundelkhand ...

  9. Experimental 2.5-Gb/s QPSK WDM phase-modulated radio-over-fiber link with digital demodulation by a K-means algorithm

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Caballero Jambrina, Antonio

    2010-01-01

    Highest reported bit rate of 2.5 Gb/s for optically phase modulated radio-over-fiber (RoF) link, employing digital coherent detection, is demonstrated. Demodulation of 3$,times,$ 2.5 Gb/s quadrature phase-shift keying modulated wavelength-division-multiplexed RoF channels is achieved after 79 km ...... of transmission through deployed fiber. Error-free performance (bit-error rate corresponding to $10^{{-}4}$) is achieved using a digital coherent receiver in combination with a $K$-means algorithm for radio-frequency phase recovery....

  10. Development and test of ion emitter modules for the projects ASPOC/CLUSTER (8th project year) and EQUATOR-S (4th project year). Final report

    International Nuclear Information System (INIS)

    Fehringer, H.M.; Ruedenauer, F.G.; Steiger, W.

    1997-02-01

    Not only was the failure of flight V001 of the newly developed ARIANE-V rocket a disaster for the European space industry and a drawback in the highly competitive launcher business, with the loss of its payload, ESA's 4 scientific CLUSTER satellites, also the work and expectations of hundreds of scientists and engineers were buried in the swamps of French Guyana. The Austrian experiment ASPOC, for which ion emitters have been developed under the contract reported here, was one of the 12 instruments onboard. In a meeting following the launch failure ESA's Science Policy Committee (SPC) decided to immediately rebuild one CLUSTER satellite and use the instrument spare models as the payload. This new mission was called PHOENIX. Furthermore, the SPC initiated studies to look for options of a CLUSTER reflight. The final decision about the future of the CLUSTER project is now due in February 1997. Since ASPOC has been lost, this report only very shortly deals with the work done up to the launch date. More important are two aspects: First, the ion emitters, the product which has been developed within this long term project, are of such high quality that they survived both the explosion of the rocket and the subsequent free fall from 3.6 km height. Ten ion emitters have been recovered from the debris and all of them were still working well. Second, new applications both in the scientific and in the commercial area have been found for the indium ion sources. Under an ESA contract their potential use as ion thrusters has recently successfully been studied. A further contract now has been placed for the development of a prototype ion thruster. Furthermore, the indium ion source has been selected as the primary ion emitter for the time of flight mass spectrometer COSIMA, a key instrument of the ROSETTA mission. Concerning EQUATOR-S, a new set of ion emitter modules has to be built, as those originally foreseen for EQUATOR-S are now being used for PHOENIX. The respective

  11. Link About It: Information Asymmetry, Knowledge Pooling and Syndication in Project Finance Lending

    NARCIS (Netherlands)

    Contreras, Gaby; Bos, Jaap; Kleimeier, Stefanie

    2018-01-01

    In a collaborative setting, banks have an additional way to deal with asymmetric information between themselves and their borrowers: by pooling information. We explore the extent to which lead arrangers in the project finance syndicated lending market strategically choose their new partners in order

  12. The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data

    NARCIS (Netherlands)

    Kohler, S.; Doelken, S.C.; Mungall, C.J.; Bauer, S.; Firth, H.V.; Bailleul-Forestier, I.; Black, G.C.M.; Brown, D.L.; Brudno, M.; Campbell, J.; FitzPatrick, D.R.; Eppig, J.T.; Jackson, A.P.; Freson, K.; Girdea, M.; Helbig, I.; Hurst, J.A.; Jahn, J.; Jackson, L.G.; Kelly, A.M.; Ledbetter, D.H.; Mansour, S.; Martin, C.L.; Moss, C.; Mumford, A.; Ouwehand, W.H.; Park, S.M.; Riggs, E.R.; Scott, R.H.; Sisodiya, S.; Vooren, S. van der; Wapner, R.J.; Wilkie, A.O.; Wright, C.F.; Silfhout, A.T. van; Leeuw, N. de; Vries, B. de; Washingthon, N.L.; Smith, C.L.; Westerfield, M.; Schofield, P.; Ruef, B.J.; Gkoutos, G.V.; Haendel, M.; Smedley, D.; Lewis, S.E.; Robinson, P.N.

    2014-01-01

    The Human Phenotype Ontology (HPO) project, available at http://www.human-phenotype-ontology.org, provides a structured, comprehensive and well-defined set of 10,088 classes (terms) describing human phenotypic abnormalities and 13,326 subclass relations between the HPO classes. In addition we have

  13. Resolving Conflicts: Getting along with Co-Workers. JobLink Winning at Work Instructor's Manual, Module 8.

    Science.gov (United States)

    Coast Community Coll. District, Costa Mesa, CA.

    This manual is a guide to an interactive training program designed to address key skills necessary in today's high performance workplace. The module is intended to meet the learning needs of production workers who may have limited basic skills or literacy. This module, which addresses conflict resolution, focuses on helping employees understand…

  14. Enabling 4-Lane Based 400 G Client-Side Transmission Links with MultiCAP Modulation

    DEFF Research Database (Denmark)

    Tatarczak, Anna; Iglesias Olmedo, Miguel; Zuo, Tianjian

    2015-01-01

    We propose a uniform solution for a future client-side 400 G Ethernet standard based on MultiCAP advanced modulation format, intensity modulation, and direct detection. It employs 4 local area networks-wavelength division multiplexing (LAN-WDM) lanes in 1300 nm wavelength band and parallel optics...

  15. Performance Analysis of Polarization Modulated DirectDetection Optical CDMA Systems over Turbulent FSO LinksModeled by the Gamma-Gamma Distribution

    Directory of Open Access Journals (Sweden)

    Fan Bai

    2015-01-01

    Full Text Available This paper proposes a theoretical study to characterize the transmission of optical code division multiple access (CDMA systems deploying polarization shift keying (PolSK over a free space optical (FSO link under the impact of atmospheric turbulence. In our analysis, a novel transceiver architecture for atmospheric OCDMA FSO systems based on polarization modulation with direct detection is proposed and discussed. A detailed analytical model for PolSK-OCDMA systems over a turbulent FSO link is provided. Further, we derive a closed-form bit error ratio (BER and outage probability expressions, taking into account the multiple-access interference (MAI, optical noise and the atmospheric turbulence effect on the FSO link modeled by the Gamma-Gamma distribution. Finally, the results of this study show the most significant parameters that degrade the transmission performance of the PolSK-OCDMA signal over FSO links and indicate that the proposed approach offers improved bit error ratio (BER performances compared to the on-off-keying (OOK modulation scheme in the presence of turbulence.

  16. D-Zero detector electronics Run IIb upgrade project: VME LVDS SERDES buff (VLSB) module specification

    Energy Technology Data Exchange (ETDEWEB)

    Rapisarda, Stefano M. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Rubinov, Paul M. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Wilcer, Neal G. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2011-03-09

    The D0 VME64 LVDS SERDES Buffer (D0 VLSB) is a VME64 [Ref. ] single wide 6U module used for testing the Analog Front-End boards system [Ref. ]. The module is a custom LVDS SERDES Buffer with 4 LVDS inputs channels and can be operated stand-alone with minimal additional hardware. The current testing needs require only a 4 channel D0 VLSB module but the design allows system expansion to multiple modules. A D0 VLSB module can receive/generate trigger signals over two Lemo© [Ref. ] connectors on the module front panel. A normal test system configuration consist of a VME 64 subrack were slot 1 is occupied by a VME subrack controller and the D0 VLSB cards will occupy one or more of the remaining slots.

  17. Activation of afferent renal nerves modulates RVLM-projecting PVN neurons.

    Science.gov (United States)

    Xu, Bo; Zheng, Hong; Liu, Xuefei; Patel, Kaushik P

    2015-05-01

    Renal denervation for the treatment of hypertension has proven to be successful; however, the underlying mechanism/s are not entirely clear. To determine if preautonomic neurons in the paraventricular nucleus (PVN) respond to afferent renal nerve (ARN) stimulation, extracellular single-unit recording was used to investigate the contribution of the rostral ventrolateral medulla (RVLM)-projecting PVN (PVN-RVLM) neurons to the response elicited during stimulation of ARN. In 109 spontaneously active neurons recorded in the PVN of anesthetized rats, 25 units were antidromically activated from the RVLM. Among these PVN-RVLM neurons, 84% (21/25) were activated by ARN stimulation. The baseline discharge rate was significantly higher in these neurons than those PVN-RVLM neurons not activated by ARN stimulation (16%, 4/25). The responsiveness of these neurons to baroreflex activation induced by phenylephrine and activation of cardiac sympathetic afferent reflex (CSAR) was also examined. Almost all of the PVN neurons that responded to ARN stimulation were sensitive to baroreflex (95%) and CSAR (100%). The discharge characteristics for nonevoked neurons (not activated by RVLM antidromic stimulation) showed that 23% of these PVN neurons responded to ARN stimulation. All the PVN neurons that responded to ARN stimulation were activated by N-methyl-D-aspartate, and these responses were attenuated by the glutamate receptor blocker AP5. These experiments demonstrated that sensory information originating in the kidney is integrated at the level of preautonomic neurons within the PVN, providing a novel mechanistic insight for use of renal denervation in the modulation of sympathetic outflow in disease states such as hypertension and heart failure. Copyright © 2015 the American Physiological Society.

  18. Design and implementation of a web-based patient portal linked to an electronic health record designed to improve medication safety: the Patient Gateway medications module

    Directory of Open Access Journals (Sweden)

    Jeffrey Schnipper

    2008-07-01

    Full Text Available In this article we describe the background, design, and preliminary results of a medications module within Patient Gateway (PG, a patient portal linked to an electronic health record (EHR. The medications module is designed to improve the accuracy of medication lists within the EHR, reduce adverse drug events and improve patient_provider communication regarding medications and allergies in several primary care practices within a large integrated healthcare delivery network. This module allows patients to view and modify the list of medications and allergies from the EHR, report nonadherence, side effects and other medication-related problems and easily communicate this information to providers, who can verify the information and update the EHR as needed. Usage and satisfaction data indicate that patients found the module easy to use, felt that it led to their providers having more accurate information about them and enabled them to feel more prepared for their forthcoming visits. Further analyses will determine the effects of this module on important medication-related outcomes and identify further enhancements needed to improve on this approach.

  19. Remarkable link between projected uncertainties of Arctic sea-ice decline and winter Eurasian climate

    Science.gov (United States)

    Cheung, Hoffman H. N.; Keenlyside, Noel; Omrani, Nour-Eddine; Zhou, Wen

    2018-01-01

    We identify that the projected uncertainty of the pan-Arctic sea-ice concentration (SIC) is strongly coupled with the Eurasian circulation in the boreal winter (December-March; DJFM), based on a singular value decomposition (SVD) analysis of the forced response of 11 CMIP5 models. In the models showing a stronger sea-ice decline, the Polar cell becomes weaker and there is an anomalous increase in the sea level pressure (SLP) along 60°N, including the Urals-Siberia region and the Iceland low region. There is an accompanying weakening of both the midlatitude westerly winds and the Ferrell cell, where the SVD signals are also related to anomalous sea surface temperature warming in the midlatitude North Atlantic. In the Mediterranean region, the anomalous circulation response shows a decreasing SLP and increasing precipitation. The anomalous SLP responses over the Euro-Atlantic region project on to the negative North Atlantic Oscillation-like pattern. Altogether, pan-Arctic SIC decline could strongly impact the winter Eurasian climate, but we should be cautious about the causality of their linkage.

  20. The SMAP Level-4 ECO Project: Linking the Terrestrial Water and Carbon Cycles

    Science.gov (United States)

    Kolassa, J.; Reichle, R. H.; Liu, Qing; Koster, Randal D.

    2017-01-01

    The SMAP (Soil Moisture Active Passive) Level-4 projects aims to develop a fully coupled hydrology-vegetation data assimilation algorithm to generate improved estimates of modeled hydrological fields and carbon fluxes. This includes using the new NASA Catchment-CN (Catchment-Carbon-Nitrogen) model, which combines the Catchment land surface hydrology model with dynamic vegetation components from the Community Land Model version 4 (CLM4). As such, Catchment-CN allows a more realistic, fully coupled feedback between the land hydrology and the biosphere. The L4 ECO project further aims to inform the model through the assimilation of Soil Moisture Active Passive (SMAP) brightness temperature observations as well as observations of Moderate Resolution Imaging Spectroradiometer (MODIS) fraction of absorbed photosynthetically active radiation (FPAR). Preliminary results show that the assimilation of SMAP observations leads to consistent improvements in the model soil moisture skill. An evaluation of the Catchment-CN modeled vegetation characteristics showed that a calibration of the model's vegetation parameters is required before an assimilation of MODIS FPAR observations is feasible.

  1. Do Fanconi anemia genes control cell response to cross-linking agents by modulating cytochrome P-450 reductase activity?

    NARCIS (Netherlands)

    Kruyt, FAE; Youssoufian, H

    2000-01-01

    The Fanconi anemia (FA) genes play an important role in maintaining chromosomal stability and the defense of mammalian cells against cross-linking agents, such as cisplatin and mitomycin C (MMC). Cells derived from FA patients display a characteristic hypersensitivity toward cross-linking agents.

  2. Radio over fiber link with adaptive order n‐QAM optical phase modulated OFDM and digital coherent detection

    DEFF Research Database (Denmark)

    Arlunno, Valeria; Borkowski, Robert; Guerrero Gonzalez, Neil

    2011-01-01

    Successful digital coherent demodulation of asynchronous optical phase‐modulated adaptive order QAM (4, 16, and 64) orthogonal frequency division multiplexing signals is achieved by a single reconfigurable digital receiver after 78 km of optical deployed fiber transmission....

  3. Cyclophilin-B Modulates Collagen Cross-linking by Differentially Affecting Lysine Hydroxylation in the Helical and Telopeptidyl Domains of Tendon Type I Collagen.

    Science.gov (United States)

    Terajima, Masahiko; Taga, Yuki; Chen, Yulong; Cabral, Wayne A; Hou-Fu, Guo; Srisawasdi, Sirivimol; Nagasawa, Masako; Sumida, Noriko; Hattori, Shunji; Kurie, Jonathan M; Marini, Joan C; Yamauchi, Mitsuo

    2016-04-29

    Covalent intermolecular cross-linking provides collagen fibrils with stability. The cross-linking chemistry is tissue-specific and determined primarily by the state of lysine hydroxylation at specific sites. A recent study on cyclophilin B (CypB) null mice, a model of recessive osteogenesis imperfecta, demonstrated that lysine hydroxylation at the helical cross-linking site of bone type I collagen was diminished in these animals (Cabral, W. A., Perdivara, I., Weis, M., Terajima, M., Blissett, A. R., Chang, W., Perosky, J. E., Makareeva, E. N., Mertz, E. L., Leikin, S., Tomer, K. B., Kozloff, K. M., Eyre, D. R., Yamauchi, M., and Marini, J. C. (2014) PLoS Genet 10, e1004465). However, the extent of decrease appears to be tissue- and molecular site-specific, the mechanism of which is unknown. Here we report that although CypB deficiency resulted in lower lysine hydroxylation in the helical cross-linking sites, it was increased in the telopeptide cross-linking sites in tendon type I collagen. This resulted in a decrease in the lysine aldehyde-derived cross-links but generation of hydroxylysine aldehyde-derived cross-links. The latter were absent from the wild type and heterozygous mice. Glycosylation of hydroxylysine residues was moderately increased in the CypB null tendon. We found that CypB interacted with all lysyl hydroxylase isoforms (isoforms 1-3) and a putative lysyl hydroxylase-2 chaperone, 65-kDa FK506-binding protein. Tendon collagen in CypB null mice showed severe size and organizational abnormalities. The data indicate that CypB modulates collagen cross-linking by differentially affecting lysine hydroxylation in a site-specific manner, possibly via its interaction with lysyl hydroxylases and associated molecules. This study underscores the critical importance of collagen post-translational modifications in connective tissue formation. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  4. Cyclophilin-B Modulates Collagen Cross-linking by Differentially Affecting Lysine Hydroxylation in the Helical and Telopeptidyl Domains of Tendon Type I Collagen*

    Science.gov (United States)

    Terajima, Masahiko; Taga, Yuki; Chen, Yulong; Cabral, Wayne A.; Hou-Fu, Guo; Srisawasdi, Sirivimol; Nagasawa, Masako; Sumida, Noriko; Hattori, Shunji; Kurie, Jonathan M.; Marini, Joan C.; Yamauchi, Mitsuo

    2016-01-01

    Covalent intermolecular cross-linking provides collagen fibrils with stability. The cross-linking chemistry is tissue-specific and determined primarily by the state of lysine hydroxylation at specific sites. A recent study on cyclophilin B (CypB) null mice, a model of recessive osteogenesis imperfecta, demonstrated that lysine hydroxylation at the helical cross-linking site of bone type I collagen was diminished in these animals (Cabral, W. A., Perdivara, I., Weis, M., Terajima, M., Blissett, A. R., Chang, W., Perosky, J. E., Makareeva, E. N., Mertz, E. L., Leikin, S., Tomer, K. B., Kozloff, K. M., Eyre, D. R., Yamauchi, M., and Marini, J. C. (2014) PLoS Genet. 10, e1004465). However, the extent of decrease appears to be tissue- and molecular site-specific, the mechanism of which is unknown. Here we report that although CypB deficiency resulted in lower lysine hydroxylation in the helical cross-linking sites, it was increased in the telopeptide cross-linking sites in tendon type I collagen. This resulted in a decrease in the lysine aldehyde-derived cross-links but generation of hydroxylysine aldehyde-derived cross-links. The latter were absent from the wild type and heterozygous mice. Glycosylation of hydroxylysine residues was moderately increased in the CypB null tendon. We found that CypB interacted with all lysyl hydroxylase isoforms (isoforms 1–3) and a putative lysyl hydroxylase-2 chaperone, 65-kDa FK506-binding protein. Tendon collagen in CypB null mice showed severe size and organizational abnormalities. The data indicate that CypB modulates collagen cross-linking by differentially affecting lysine hydroxylation in a site-specific manner, possibly via its interaction with lysyl hydroxylases and associated molecules. This study underscores the critical importance of collagen post-translational modifications in connective tissue formation. PMID:26934917

  5. Pittsburgh Science Technology Society Project: Instruction Modules. Interrelationships Science--Technology--Society.

    Science.gov (United States)

    O'Brien, George, Ed.

    This collection of instruction modules studies the interactions of science, technology, and society (STS) using five activity sets. The introduction module includes activities which show students the STS relationships in their world, develop good organizational skills, develop an understanding of who and what a scientist is, develop graphing…

  6. Development of Hybrid Courses Utilizing Modules as an Objective in ATE Projects

    Science.gov (United States)

    Payne, James E.; Murphy, Richard M.; Payne, Linda L.

    2017-01-01

    Orangeburg-Calhoun Technical College (OCtech) has been awarded two National Science Foundation Advanced Technological Education (NSF-ATE) grants since 2011 that have the development of module-based hybrid courses in Engineering Technology and Mechatronics as objectives. In this article, the advantages and challenges associated with module-based…

  7. Projection-based circular constrained state estimation and fusion over long-haul links

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Qiang [ORNL; Rao, Nageswara S. [ORNL

    2017-07-01

    In this paper, we consider a scenario where sensors are deployed over a large geographical area for tracking a target with circular nonlinear constraints on its motion dynamics. The sensor state estimates are sent over long-haul networks to a remote fusion center for fusion. We are interested in different ways to incorporate the constraints into the estimation and fusion process in the presence of communication loss. In particular, we consider closed-form projection-based solutions, including rules for fusing the estimates and for incorporating the constraints, which jointly can guarantee timely fusion often required in realtime systems. We test the performance of these methods in the long-haul tracking environment using a simple example.

  8. Health and Environment Linked for Information Exchange (HELIX)-Atlanta: A CDC-NASA Joint Environmental Public Health Tracking Collaborative Project

    Science.gov (United States)

    Al-Hamdan, Mohammad; Luvall, Jeff; Crosson, Bill; Estes, Maury; Limaye, Ashutosh; Quattrochi, Dale; Rickman, Doug

    2008-01-01

    HELIX-Atlanta was developed to support current and future state and local EPHT programs to implement data linking demonstration projects which could be part of the CDC EPHT Network. HELIX-Atlanta is a pilot linking project in Atlanta for CDC to learn about the challenges the states will encounter. NASA/MSFC and the CDC are partners in linking environmental and health data to enhance public health surveillance. The use of NASA technology creates value added geospatial products from existing environmental data sources to facilitate public health linkages. Proving the feasibility of the approach is the main objective

  9. Method for Backplane Data Communication with the VME Rear Transition Modules Developed for the ATLAS FTK Project

    CERN Document Server

    Bogdan, M; The ATLAS collaboration; Piendibene, M; Shochet, M; Tompkins, L

    2013-01-01

    This paper presents a method to achieve backplane data transfer capabilities to and from a VME Rear Transition Module (RTM), while being in full compliance with the VME64/VIPA Specification. The VMEbus is specified for data transfers only with boards plugged on the front side of the subrack. The RTMs receive power from the crate, but are not part of the actual data transfer bus. They do not plug into the J1 connector, and have no access to backplane interface logic. In this implementation, the RTM uses the feed-through pins located in the J2 connector to communicate with the corresponding front module. The front module's internal data, address, and control buses are extended to the rear. This allows the front module's interface block to control data transfers for logic devices on both sides of the same slot. All usual VME protocols to logic devices on the RTM become possible without any software adaptation. This method was implemented on several prototype modules developed for the ATLAS FTK Project. The full ...

  10. System and technique for retrieving depth information about a surface by projecting a composite image of modulated light patterns

    Science.gov (United States)

    Hassebrook, Laurence G. (Inventor); Lau, Daniel L. (Inventor); Guan, Chun (Inventor)

    2010-01-01

    A technique, associated system and program code, for retrieving depth information about at least one surface of an object, such as an anatomical feature. Core features include: projecting a composite image comprising a plurality of modulated structured light patterns, at the anatomical feature; capturing an image reflected from the surface; and recovering pattern information from the reflected image, for each of the modulated structured light patterns. Pattern information is preferably recovered for each modulated structured light pattern used to create the composite, by performing a demodulation of the reflected image. Reconstruction of the surface can be accomplished by using depth information from the recovered patterns to produce a depth map/mapping thereof. Each signal waveform used for the modulation of a respective structured light pattern, is distinct from each of the other signal waveforms used for the modulation of other structured light patterns of a composite image; these signal waveforms may be selected from suitable types in any combination of distinct signal waveforms, provided the waveforms used are uncorrelated with respect to each other. The depth map/mapping to be utilized in a host of applications, for example: displaying a 3-D view of the object; virtual reality user-interaction interface with a computerized device; face--or other animal feature or inanimate object--recognition and comparison techniques for security or identification purposes; and 3-D video teleconferencing/telecollaboration.

  11. Linking Project-Based Interdisciplinary Learning and Recommended Professional Competencies with Business Management, Digital Media, Distance Learning, Engineering Technology, and English

    Science.gov (United States)

    Bender, Melinda; Fulwider, Miles; Stemkoski, Michael J.

    2008-01-01

    This paper encourages the investigation of real world problems by students and faculty and links recommended student competencies with project based learning. In addition to the traditional course objectives, project-based learning (PBL) uses real world problems for classroom instruction and fieldwork to connect students, instructors, and industry…

  12. The Genotype-Tissue Expression (GTEx Project: Linking Clinical Data with Molecular Analysis to Advance Personalized Medicine

    Directory of Open Access Journals (Sweden)

    Judy C. Keen

    2015-02-01

    Full Text Available Evaluation of how genetic mutations or variability can directly affect phenotypic outcomes, the development of disease, or determination of a tailored treatment protocol is fundamental to advancing personalized medicine. To understand how a genotype affects gene expression and specific phenotypic traits, as well as the correlative and causative associations between such, the Genotype-Tissue Expression (GTEx Project was initiated The GTEx collection of biospecimens and associated clinical data links extensive clinical data with genotype and gene expression data to provide a wealth of data and resources to study the underlying genetics of normal physiology. These data will help inform personalized medicine through the identification of normal variation that does not contribute to disease. Additionally, these data can lead to insights into how gene variation affects pharmacodynamics and individualized responses to therapy.

  13. Advanced Modulation Formats in Cognitive Optical Networks: EU project CHRON Demonstration

    DEFF Research Database (Denmark)

    Borkowski, Robert; Caballero Jambrina, Antonio; Klonidis, Dimitris

    2014-01-01

    We demonstrate real-time path establishment and switching of coherent modulation formats (QPSK, 16QAM) within an optical network driven by cognitive algorithms. Cognition aims at autonomous configuration optimization to satisfy quality of transmission requirements.......We demonstrate real-time path establishment and switching of coherent modulation formats (QPSK, 16QAM) within an optical network driven by cognitive algorithms. Cognition aims at autonomous configuration optimization to satisfy quality of transmission requirements....

  14. City and County Solar PV Training Program, Module 2: Screening and Identifying PV Projects

    Energy Technology Data Exchange (ETDEWEB)

    Elgqvist, Emma M [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-04-09

    When screening and identifying PV projects, cities and counties should understand the different factors that impact the technical and economic potential of a PV project, the steps of the PV screening process, and how to use REopt Lite to screen a site for PV and storage project potential.

  15. Using linked data to evaluate motor vehicle crashes involving elderly drivers in Connecticut : Crash Outcome Data Evaluation System (CODES) linked data demonstration project

    Science.gov (United States)

    1999-09-01

    A deterministic algorithm was developed which allowed data from Department of Transportation motor vehicle crash records, state mortality registry records, and hospital admission and emergency department records to be linked for analysis of the impac...

  16. Using linked data to evaluate collisions with fixed objects in Pennsylvania : Crash Outcome Data Evaluation System (CODES) linked data demonstration project

    Science.gov (United States)

    1998-10-01

    This report uses police-reported motor vehicle crash data linked to Emergency Medical Services data and hospital discharge data to evaluate the relative risk of injury posed by specific roadside objects in Pennsylvania. The report focuses primarily o...

  17. Using linked data to evaluate medical and financial outcomes of motor vehicle crashes in Connecticut : Crash Outcome Data Evaluation System (CODES) linked data demonstration project

    Science.gov (United States)

    1999-09-01

    A deterministic algorithm was developed which allowed data from Department of Transportation motor vehicle crash records, state mortality registry records, and hospital admission and emergency department records to be linked for analysis of the finan...

  18. Using linked data to evaluate hospital charges for motor vehicle crash victims in Pennsylvania : Crash Outcome Data Evaluation System (CODES) linked data demonstration project

    Science.gov (United States)

    1998-10-01

    The report uses police-reported crash data that have been linked to hospital discharge data to evaluate charges for hospital care provided to motor vehicle crash victims in Pennsylvania. Approximately 17,000 crash victims were hospitalized in Pennsyl...

  19. Evaluation of High-Speed EML-based IM/DD links with PAM Modulations and Low-Complexity Equalization

    DEFF Research Database (Denmark)

    Pang, Xiaodan; Ozolins, Oskars; Gaiarin, Simone

    2017-01-01

    We experimentally evaluated up to 96 Gb/s/lambda PAM IM/DD transmissions with an EML and digital equalizations. Symbol-spaced FFE/DFEs with fewer than 10 taps are shown being sufficient for a high and stable performance over a 4 km SMF link....

  20. Urban Environmental Education Project, Curriculum Module VI: Solid Waste - Trash or Treasure?

    Science.gov (United States)

    Biglan, Barbara

    Included in this module are four activities dealing with issues of solid waste disposal relative to urban concerns. Included activities are: (1) sources and composition of solid waste; (2) a "garbage game"; (3) disposal options for solid waste; and (4) an example county plan for solid waste disposal. Also included are an overview, teacher…

  1. Diversifying Assessment through Multimedia Creation in a Non-Technical Module: Reflections on the MAIK Project

    Science.gov (United States)

    Cox, Andrew M.; Vasconcelos, Ana Cristina; Holdridge, Peter

    2010-01-01

    Creation of multimedia (MM) could be a valuable diversification of assessment methods within non-technical modules. The apparent popularity of sites based on user-generated video content such as YouTube and also of podcasting suggests that relevant skills and interest are becoming more mainstream. Translating book learned knowledge into visual…

  2. Urban Environmental Education Project, Curriculum Module III: Urban Transportation - Where Are We Going?

    Science.gov (United States)

    Bell, Ellen

    Included in this module are five activities dealing with modes of transportation in the urban environment. The activities include: (1) a discussion of transportation considerations in urban areas; (2) discussion of bikeways and their desirability in the urban environment; (3) the bikeway and the environment; (4) designing a bikeway; and (5)…

  3. Elderly Service Workers' Training Project. Block B: Cultural Gerontology. Module B.2: German Culture.

    Science.gov (United States)

    Harvey, Dexter; Cap, Orest

    This learning module, which is part of a three-block series intended to help human service workers develop the skills necessary to solve the problems encountered in their daily contact with elderly clients of different cultural backgrounds, deals with German culture. The first section provides background information about the German migrations to…

  4. 75 FR 79008 - Proposed Collection; Comment Request; Study of Substance Abuse doc.com Module Project

    Science.gov (United States)

    2010-12-17

    ... referral to treatment for patients who abuse substances. The overall goal of this project is to assess the... provide significant services directly to the public to survey customers to determine the kind and quality of services they want and their level of satisfaction with existing services. The project will...

  5. Nonlinear intermodulation distortion suppression in coherent analog fiber optic link using electro-optic polymeric dual parallel Mach-Zehnder modulator.

    Science.gov (United States)

    Kim, Seong-Ku; Liu, Wei; Pei, Qibing; Dalton, Larry R; Fetterman, Harold R

    2011-04-11

    A linearized dual parallel Mach-Zehnder modulator (DPMZM) based on electro-optic (EO) polymer was both fabricated, and experimentally used to suppress the third-order intermodulation distortion (IMD3) in a coherent analog fiber optic link. This optical transmitter design was based on a new EO chromophore called B10, which was synthesized for applications dealing with the fiber-optic communication systems. The chromophore was mixed with amorphous polycarbonate (APC) to form the waveguide's core material. The DPMZM was configured with two MZMs, of different lengths in parallel, with unbalanced input and output couplers and a phase shifter in one arm. In this configuration each of the MZMs carried a different optical power, and imposed a different depth of optical modulation. When the two optical beams from the MZMs were combined to generate the transmitted signal it was possible to set the IMD3 produced by each modulator to be equal in amplitude but 180° out of phase from the other. Therefore, the resulting IMD3 of the DPMZM transmitter was effectively canceled out during two-tone experiments. A reduction of the IMD3 below the noise floor was observed while leaving fifth-order distortion (IMD5) as the dominant IMD product. This configuration has the capability of broadband operation and shot-noise limited operation simultaneously. © 2011 Optical Society of America

  6. SU-F-J-121: Dosimetric Evaluation of Active Breathing Coordinator-Response Gating System Linked to Linear Accelerator in Volumetric Modulated Arc Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S; Zheng, Y; Albani, D; Colussi, V; Dorth, J; Sohn, J [Case Western University, Cleveland, OH (United States)

    2016-06-15

    Purpose: To reduce internal target volume (ITV), respiratory management is a must in imaging and treatment for lung, liver, and breast cancers. We investigated the dosimetric accuracy of VMAT treatment delivery with a Response™ gating system linked to linear accelerator. Methods: The Response™ gating module designed to directly control radiation beam by breath-holding with a ABC system (Elekta AB, Stockholm, Sweden) was tested for VMAT treatments. Seven VMAT plans including three conventional and four stereotactic body radiotherapy (SBRT) cases were evaluated. Each plan was composed of two or four arcs of 6MV radiation beam with prescribed dose ranged from 1.8 to 9 Gy per fraction. Each plan was delivered continuously without gating and delivered with multiple interruptions by the ResponseTM gating module with a 20 or 30 second breath-holding period. MapCheck2 and Gafchromic EBT3 films sandwiched in MapPHAN were used to measure the delivered dose with and without gating. Films were scanned on a flatbed color scanner, and red channel was extracted for film dosimetry. Gamma analysis was performed to analyze the dosimetrical accuracy of the radiation delivery with gating. Results: The measured doses with gating remarkably agree with the planned dose distributions in the results of gamma index passing rate (within 20% isodose; >98% for 3%/3mm and >92% for 2%/2mm in MapCheck2, and >91% for 3%/3mm criteria in EBT3 film except one case which was for large target and highly modulated). No significant difference (student t-test: p-value < 0.0005) was shown between the doses delivered with and without gating. There was no indication of radiation gap or overlapping during deliver interruption in film dosimetry. Conclusion: The Response™ gating system can be safely used during VMAT treatment. The accurate performance of the gating system linked to ABC can contribute to ITV reduction for SBRT using VMAT.

  7. Demonstration of free-space optical communication for long-range data links between balloons on Project Loon

    Science.gov (United States)

    Moision, Bruce; Erkmen, Baris; Keyes, Edward; Belt, Todd; Bowen, Oliver; Brinkley, Devin; Csonka, Paul; Eglington, Michael; Kazmierski, Andrei; Kim, Nam-hyong; Moody, John; Tu, Thanh; Vermeer, William

    2017-02-01

    Internet connectivity is limited and in some cases non-existent for a significant part of the world's population. Project Loon aims to address this with a network of high-altitude balloons traveling in the stratosphere, at an altitude of approximately 20 km. The balloons navigate by using the stratified wind layers at different altitudes, adjusting the balloon's altitude to catch winds in a desired direction. Data transfer is achieved by 1) uplinking a signal from an Internet-connected ground station to a balloon terminal, 2) crosslinking the signal through the balloon network to reach the geographic area of the users, and 3) downlinking the signal directly to the end-users' phones or other LTE-enabled devices. We describe Loon's progress on utilizing free-space optical communications (FSOC) for the inter-balloon crosslinks. FSOC, offering high data rates and long communication ranges, is well-suited for communication between high-altitude platforms. A stratospheric link is sufficiently high to be above weather events (clouds, fog, rain, etc.), and the impact of atmospheric turbulence is significantly weaker than at ground level. In addition, being in the stratosphere as opposed to space helps avoid the typical challenges faced by space-based systems, namely operation in a vacuum environment with significant radiation. Finally, the angular pointing disturbances introduced by a floating balloon-based platform are notably less than any propelled platform, which simplifies the disturbance rejection requirements on the FSOC system. We summarize results from Project Loon's early-phase experimental inter-balloon links at 20 km altitude, demonstrating full duplex 130 Mbps throughput at distances in excess of 100 km over the course of several-day flights. The terminals utilize a monostatic design, with dual wavelengths for communication and a dedicated wide-angle beacon for pointing, acquisition, and tracking. We summarize the constraints on the terminal design, and the

  8. A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages.

    Science.gov (United States)

    Ziemba, Brian P; Falke, Joseph J

    2018-01-01

    The leukocyte chemosensory pathway detects attractant gradients and directs cell migration to sites of inflammation, infection, tissue damage, and carcinogenesis. Previous studies have revealed that local Ca2+ and PIP3 signals at the leading edge of polarized leukocytes play central roles in positive feedback loop essential to cell polarization and chemotaxis. These prior studies showed that stimulation of the leading edge Ca2+ signal can strongly activate PI3K, thereby triggering a larger PIP3 signal, but did not elucidate the mechanistic link between Ca2+ and PIP3 signaling. A hypothesis explaining this link emerged, postulating that Ca2+-activated PKC displaces the MARCKS protein from plasma membrane PIP2, thereby releasing sequestered PIP2 to serve as the target and substrate lipid of PI3K in PIP3 production. In vitro single molecule studies of the reconstituted pathway on lipid bilayers demonstrated the feasibility of this PKC-MARCKS-PI3K regulatory module linking Ca2+ and PIP3 signals in the reconstituted system. The present study tests the model predictions in live macrophages by quantifying the effects of: (a) two pathway activators-PDGF and ATP that stimulate chemoreceptors and Ca2+ influx, respectively; and (b) three pathway inhibitors-wortmannin, EGTA, and Go6976 that inhibit PI3K, Ca2+ influx, and PKC, respectively; on (c) four leading edge activity sensors-AKT-PH-mRFP, CKAR, MARCKSp-mRFP, and leading edge area that report on PIP3 density, PKC activity, MARCKS membrane binding, and leading edge expansion/contraction, respectively. The results provide additional evidence that PKC and PI3K are both essential elements of the leading edge positive feedback loop, and strongly support the existence of a PKC-MARCKS-PI3K regulatory module linking the leading edge Ca2+ and PIP3 signals. As predicted, activators stimulate leading edge PKC activity, displacement of MARCKS from the leading edge membrane and increased leading edge PIP3 levels, while inhibitors

  9. A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages.

    Directory of Open Access Journals (Sweden)

    Brian P Ziemba

    Full Text Available The leukocyte chemosensory pathway detects attractant gradients and directs cell migration to sites of inflammation, infection, tissue damage, and carcinogenesis. Previous studies have revealed that local Ca2+ and PIP3 signals at the leading edge of polarized leukocytes play central roles in positive feedback loop essential to cell polarization and chemotaxis. These prior studies showed that stimulation of the leading edge Ca2+ signal can strongly activate PI3K, thereby triggering a larger PIP3 signal, but did not elucidate the mechanistic link between Ca2+ and PIP3 signaling. A hypothesis explaining this link emerged, postulating that Ca2+-activated PKC displaces the MARCKS protein from plasma membrane PIP2, thereby releasing sequestered PIP2 to serve as the target and substrate lipid of PI3K in PIP3 production. In vitro single molecule studies of the reconstituted pathway on lipid bilayers demonstrated the feasibility of this PKC-MARCKS-PI3K regulatory module linking Ca2+ and PIP3 signals in the reconstituted system. The present study tests the model predictions in live macrophages by quantifying the effects of: (a two pathway activators-PDGF and ATP that stimulate chemoreceptors and Ca2+ influx, respectively; and (b three pathway inhibitors-wortmannin, EGTA, and Go6976 that inhibit PI3K, Ca2+ influx, and PKC, respectively; on (c four leading edge activity sensors-AKT-PH-mRFP, CKAR, MARCKSp-mRFP, and leading edge area that report on PIP3 density, PKC activity, MARCKS membrane binding, and leading edge expansion/contraction, respectively. The results provide additional evidence that PKC and PI3K are both essential elements of the leading edge positive feedback loop, and strongly support the existence of a PKC-MARCKS-PI3K regulatory module linking the leading edge Ca2+ and PIP3 signals. As predicted, activators stimulate leading edge PKC activity, displacement of MARCKS from the leading edge membrane and increased leading edge PIP3 levels, while

  10. The antiphasic regulatory module comprising CDF5 and its antisense RNA FLORE links the circadian clock to photoperiodic flowering.

    Science.gov (United States)

    Henriques, Rossana; Wang, Huan; Liu, Jun; Boix, Marc; Huang, Li-Fang; Chua, Nam-Hai

    2017-11-01

    Circadian rhythms of gene expression are generated by the combinatorial action of transcriptional and translational feedback loops as well as chromatin remodelling events. Recently, long noncoding RNAs (lncRNAs) that are natural antisense transcripts (NATs) to transcripts encoding central oscillator components were proposed as modulators of core clock function in mammals (Per) and fungi (frq/qrf). Although oscillating lncRNAs exist in plants, their functional characterization is at an initial stage. By screening an Arabidopsis thaliana lncRNA custom-made array we identified CDF5 LONG NONCODING RNA (FLORE), a circadian-regulated lncRNA that is a NAT of CDF5. Quantitative real-time RT-PCR confirmed the circadian regulation of FLORE, whereas GUS-staining and flowering time evaluation were used to determine its biological function. FLORE and CDF5 antiphasic expression reflects mutual inhibition in a similar way to frq/qrf. Moreover, whereas the CDF5 protein delays flowering by directly repressing FT transcription, FLORE promotes it by repressing several CDFs (CDF1, CDF3, CDF5) and increasing FT transcript levels, indicating both cis and trans function. We propose that the CDF5/FLORE NAT pair constitutes an additional circadian regulatory module with conserved (mutual inhibition) and unique (function in trans) features, able to fine-tune its own circadian oscillation, and consequently, adjust the onset of flowering to favourable environmental conditions. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  11. Insulin resistance as key factor for linking modulation of gut microbiome to health claims and dietary recommendations to tackle obesity

    NARCIS (Netherlands)

    Loman, S.; Kamp, J.W. van der

    2016-01-01

    Background: Current dietary and public health recommendations addressing obesity do not as yet include recommendations pertaining to the gut microbiome. As a corollary, no microbiome-related health claims made on foods have as yet been proposed. Scope: The MyNewGut project aims, amongst others, to

  12. PRO40 is a scaffold protein of the cell wall integrity pathway, linking the MAP kinase module to the upstream activator protein kinase C.

    Directory of Open Access Journals (Sweden)

    Ines Teichert

    2014-09-01

    Full Text Available Mitogen-activated protein kinase (MAPK pathways are crucial signaling instruments in eukaryotes. Most ascomycetes possess three MAPK modules that are involved in key developmental processes like sexual propagation or pathogenesis. However, the regulation of these modules by adapters or scaffolds is largely unknown. Here, we studied the function of the cell wall integrity (CWI MAPK module in the model fungus Sordaria macrospora. Using a forward genetic approach, we found that sterile mutant pro30 has a mutated mik1 gene that encodes the MAPK kinase kinase (MAPKKK of the proposed CWI pathway. We generated single deletion mutants lacking MAPKKK MIK1, MAPK kinase (MAPKK MEK1, or MAPK MAK1 and found them all to be sterile, cell fusion-deficient and highly impaired in vegetative growth and cell wall stress response. By searching for MEK1 interaction partners via tandem affinity purification and mass spectrometry, we identified previously characterized developmental protein PRO40 as a MEK1 interaction partner. Although fungal PRO40 homologs have been implicated in diverse developmental processes, their molecular function is currently unknown. Extensive affinity purification, mass spectrometry, and yeast two-hybrid experiments showed that PRO40 is able to bind MIK1, MEK1, and the upstream activator protein kinase C (PKC1. We further found that the PRO40 N-terminal disordered region and the central region encompassing a WW interaction domain are sufficient to govern interaction with MEK1. Most importantly, time- and stress-dependent phosphorylation studies showed that PRO40 is required for MAK1 activity. The sum of our results implies that PRO40 is a scaffold protein for the CWI pathway, linking the MAPK module to the upstream activator PKC1. Our data provide important insights into the mechanistic role of a protein that has been implicated in sexual and asexual development, cell fusion, symbiosis, and pathogenicity in different fungal systems.

  13. The HANDSS-55 Linking Equipment

    International Nuclear Information System (INIS)

    Crosby, S.

    2001-01-01

    The Bucket Translation Unit (BTU) and the Drum Handler are two of the HANDSS-55 subsystems identified as linking components. Both subsystems link other modules together by moving material to or from another module

  14. A mixed signal multi-chip module with high speed serial output links for the ATLAS Level-1 trigger

    CERN Document Server

    Pfeiffer, U

    2000-01-01

    We have built and tested a mixed signal multi-chip module (MCM) to be used in the Level-1 Pre-Processor system for the Calorimeter Trigger of the ATLAS experiment at CERN. The MCM performs high speed digital signal processing on four analogue input signals. Results are transmitted serially at a serial data rate of 800 MBd. Nine chips of different technologies are mounted on a four layer Cu substrate. ADC converters and serialiser chips are the major consumers of electrical power on the MCM, which amounts to 9 W for all dies. Special cut-out areas are used to dissipate heat directly to the copper substrate. In this paper we report on design criteria, chosen MCM technology for substrate and die mounting, experiences with the MCM operation and measurement results. (4 refs).

  15. Modulation of Ca(v)3.2 T-type calcium channel permeability by asparagine-linked glycosylation

    Czech Academy of Sciences Publication Activity Database

    Ondáčová, K.; Karmažínová, M.; Lazniewska, Joanna; Weiss, Norbert; Lacinová, L.

    2016-01-01

    Roč. 10, č. 3 (2016), s. 175-184 ISSN 1933-6950 R&D Projects: GA ČR GA15-13556S; GA MŠk 7AMB15FR015 Institutional support: RVO:61388963 Keywords : calcium channel * Ca(v)3.2 * gating * glycosylation * T-type channel Subject RIV: CE - Biochemistry Impact factor: 2.042, year: 2016

  16. Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p

    DEFF Research Database (Denmark)

    Moxley, Joel F.; Jewett, Michael Christopher; Antoniewicz, Maciek R.

    2009-01-01

    . However, the potential of systems biology approaches is limited by difficulties in integrating metabolic measurements across the functional levels of the cell despite their being most closely linked to cellular phenotype. To address this limitation, we developed a model-based approach to correlate m......RNA and metabolic flux data that combines information from both interaction network models and flux determination models. We started by quantifying 5,764 mRNAs, 54 metabolites, and 83 experimental C-13-based reaction fluxes in continuous cultures of yeast under stress in the absence or presence of global regulator...... of metabolic flux (i.e., use of different reaction pathways) by transcriptional regulation and metabolite interaction density (i.e., level of pairwise metabolite-protein interactions) as a key biosynthetic control determinant. Furthermore, this model predicted flux rewiring in studies of follow...

  17. Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders*

    Science.gov (United States)

    Li, Min; Quan, Chao; Toth, Rachel; Campbell, David G.; MacKintosh, Carol; Wang, Hong Yu; Chen, Shuai

    2015-01-01

    Diabetes is strongly associated with cognitive decline, but the molecular reasons are unknown. We found that fasting and peripheral insulin promote phosphorylation and dephosphorylation, respectively, of specific residues on brain proteins including cytoskeletal regulators such as slit-robo GTPase-activating protein 3 (srGAP3) and microtubule affinity-regulating protein kinases (MARKs), in which deficiency or dysregulation is linked to neurological disorders. Fasting activates protein kinase A (PKA) but not PKB/Akt signaling in the brain, and PKA can phosphorylate the purified srGAP3. The phosphorylation of srGAP3 and MARKs were increased when PKA signaling was activated in primary neurons. Knockdown of PKA decreased the phosphorylation of srGAP3. Furthermore, WAVE1, a protein kinase A-anchoring protein, formed a complex with srGAP3 and PKA in the brain of fasted mice to facilitate the phosphorylation of srGAP3 by PKA. Although brain cells have insulin receptors, our findings are inconsistent with the down-regulation of phosphorylation of target proteins being mediated by insulin signaling within the brain. Rather, our findings infer that systemic insulin, through a yet unknown mechanism, inhibits PKA or protein kinase(s) with similar specificity and/or activates an unknown phosphatase in the brain. Ser858 of srGAP3 was identified as a key regulatory residue in which phosphorylation by PKA enhanced the GAP activity of srGAP3 toward its substrate, Rac1, in cells, thereby inhibiting the action of this GTPase in cytoskeletal regulation. Our findings reveal novel mechanisms linking peripheral insulin sensitivity with cytoskeletal remodeling in neurons, which may help to explain the association of diabetes with neurological disorders such as Alzheimer disease. PMID:26499801

  18. Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders.

    Science.gov (United States)

    Li, Min; Quan, Chao; Toth, Rachel; Campbell, David G; MacKintosh, Carol; Wang, Hong Yu; Chen, Shuai

    2015-12-11

    Diabetes is strongly associated with cognitive decline, but the molecular reasons are unknown. We found that fasting and peripheral insulin promote phosphorylation and dephosphorylation, respectively, of specific residues on brain proteins including cytoskeletal regulators such as slit-robo GTPase-activating protein 3 (srGAP3) and microtubule affinity-regulating protein kinases (MARKs), in which deficiency or dysregulation is linked to neurological disorders. Fasting activates protein kinase A (PKA) but not PKB/Akt signaling in the brain, and PKA can phosphorylate the purified srGAP3. The phosphorylation of srGAP3 and MARKs were increased when PKA signaling was activated in primary neurons. Knockdown of PKA decreased the phosphorylation of srGAP3. Furthermore, WAVE1, a protein kinase A-anchoring protein, formed a complex with srGAP3 and PKA in the brain of fasted mice to facilitate the phosphorylation of srGAP3 by PKA. Although brain cells have insulin receptors, our findings are inconsistent with the down-regulation of phosphorylation of target proteins being mediated by insulin signaling within the brain. Rather, our findings infer that systemic insulin, through a yet unknown mechanism, inhibits PKA or protein kinase(s) with similar specificity and/or activates an unknown phosphatase in the brain. Ser(858) of srGAP3 was identified as a key regulatory residue in which phosphorylation by PKA enhanced the GAP activity of srGAP3 toward its substrate, Rac1, in cells, thereby inhibiting the action of this GTPase in cytoskeletal regulation. Our findings reveal novel mechanisms linking peripheral insulin sensitivity with cytoskeletal remodeling in neurons, which may help to explain the association of diabetes with neurological disorders such as Alzheimer disease. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. Modulation of integrin-linked kinase (ILK expression in human oesophageal squamous cell carcinoma cell lines by the EGF and TGFβ1 growth factors

    Directory of Open Access Journals (Sweden)

    Veale Robin B

    2006-04-01

    Full Text Available Abstract Background Integrin-linked kinase (ILK is a ubiquitously expressed protein kinase that has emerged as one of the points of convergence between integrin- and growth factor-signalling pathways. Results In this study we identify the ILK isoform expressed in five human oesophageal squamous cell carcinoma cell lines of South African origin as ILK1, and demonstrate its cellular distribution. ILK expression, although similar in the majority of the cell lines, did show variation. Furthermore, the ILK expressed was shown to be catalytically functional. The effect of growth factors on ILK expression was examined. An increase in ILK expression, following EGF and TGFβ1 exposure, was a trend across all the five oesophageal carcinoma cell lines tested. Conclusion These results suggest that growth factor modulation of ILK expression relies on the internalisation/recycling of growth factor receptors and stimulation of the PI3K pathway, which may have implications with regards to cell adhesion and tumourigenesis.

  20. Project EXCEL: Sheraton Wharf, Room Service Department. English Communication, Module 1.

    Science.gov (United States)

    Career Resources Development Center, Inc., San Francisco, CA.

    Project EXCEL is a federally-funded workplace literacy program involving hotel enterprises in the San Francisco (California) Bay area. Its focus is on identification and instruction of literacy skills essential to job success for limited-English-proficient (LEP) workers. Training is intended to enable employees to understand written work orders,…

  1. Project EXCEL: Holiday Inn at Union Square, Housekeeping Department. Safety and Security, Module 2.

    Science.gov (United States)

    Career Resources Development Center, Inc., San Francisco, CA.

    Project EXCEL is a federally-funded workplace literacy program involving hotel enterprises in the San Francisco (California) Bay area. Its focus is on identification and instruction of literacy skills essential to job success for limited-English-proficient (LEP) workers. Training is intended to enable employees to understand written work orders,…

  2. Rapid modulation of ultraviolet shielding in plants is influenced by solar ultraviolet radiation and linked to alterations in flavonoids.

    Science.gov (United States)

    Barnes, Paul W; Tobler, Mark A; Keefover-Ring, Ken; Flint, Stephan D; Barkley, Anne E; Ryel, Ronald J; Lindroth, Richard L

    2016-01-01

    The accumulation of ultraviolet (UV)-absorbing compounds (flavonoids and related phenylpropanoids) and the resultant decrease in epidermal UV transmittance (TUV ) are primary protective mechanisms employed by plants against potentially damaging solar UV radiation and are critical components of the overall acclimation response of plants to changing solar UV environments. Whether plants can adjust this UV sunscreen protection in response to rapid changes in UV, as occurs on a diurnal basis, is largely unexplored. Here, we use a combination of approaches to demonstrate that plants can modulate their UV-screening properties within minutes to hours, and these changes are driven, in part, by UV radiation. For the cultivated species Abelmoschus esculentus, large (30-50%) and reversible changes in TUV occurred on a diurnal basis, and these adjustments were associated with changes in the concentrations of whole-leaf UV-absorbing compounds and several quercetin glycosides. Similar results were found for two other species (Vicia faba and Solanum lycopersicum), but no such changes were detected in Zea mays. These findings reveal a much more dynamic UV-protection mechanism than previously recognized, raise important questions concerning the costs and benefits of UV-protection strategies in plants and have practical implications for employing UV to enhance crop vigor and quality in controlled environments. © 2015 John Wiley & Sons Ltd.

  3. Valenced action/inhibition learning in humans is modulated by a genetic variant linked to dopamine D2 receptor expression

    Directory of Open Access Journals (Sweden)

    Anni eRichter

    2014-08-01

    Full Text Available Motivational salience plays an important role in shaping human behavior, but recent studies demonstrate that human performance is not uniformly improved by motivation. Instead, action has been shown to dominate valence in motivated tasks, and it is particularly difficult for humans to learn the inhibition of an action to obtain a reward, but the neural mechanism behind this behavioral specificity is yet unclear. In all mammals, including humans, the monoamine neurotransmitter dopamine is particularly important in the neural manifestation of appetitively motivated behavior, and the human dopamine system is subject to considerable genetic variability. The well-studied TaqIA restriction fragment length polymorphism (rs1800497 has previously been shown to affect striatal dopamine metabolism. In this study we investigated a potential effect of this genetic variation on motivated action/inhibition learning. Two independent cohorts consisting of 87 and 95 healthy participants, respectively, were tested using the previously described valenced go/no-go learning paradigm in which participants learned the reward-associated no-go condition significantly worse than all other conditions. This effect was modulated by the TaqIA polymorphism, with carriers of the A1 allele showing a diminished learning-related performance enhancement in the rewarded no-go condition compared to the A2 homozygotes. This result highlights a modulatory role for genetic variability of the dopaminergic system in individual learning differences of action-valence interaction.

  4. Impacts of rural development on Yellowstone wildlife: linking grizzly bear Ursus arctos demographics with projected residential growth

    Science.gov (United States)

    Schwartz, Charles C.; Gude, Patricia H.; Landenburger, Lisa; Haroldson, Mark A.; Podruzny, Shannon

    2012-01-01

    Exurban development is consuming wildlife habitat within the Greater Yellowstone Ecosystem with potential consequences to the long-term conservation of grizzly bears Ursus arctos. We assessed the impacts of alternative future land-use scenarios by linking an existing regression-based simulation model predicting rural development with a spatially explicit model that predicted bear survival. Using demographic criteria that predict population trajectory, we portioned habitats into either source or sink, and projected the loss of source habitat associated with four different build out (new home construction) scenarios through 2020. Under boom growth, we predicted that 12 km2 of source habitat were converted to sink habitat within the Grizzly Bear Recovery Zone (RZ), 189 km2 were converted within the current distribution of grizzly bears outside of the RZ, and 289 km2 were converted in the area outside the RZ identified as suitable grizzly bear habitat. Our findings showed that extremely low densities of residential development created sink habitats. We suggest that tools, such as those outlined in this article, in addition to zoning and subdivision regulation may prove more practical, and the most effective means of retaining large areas of undeveloped land and conserving grizzly bear source habitat will likely require a landscape-scale approach. We recommend a focus on land conservation efforts that retain open space (easements, purchases and trades) coupled with the implementation of ‘bear community programmes’ on an ecosystem wide basis in an effort to minimize human-bear conflicts, minimize management-related bear mortalities associated with preventable conflicts and to safeguard human communities. Our approach has application to other species and areas, and it has illustrated how spatially explicit demographic models can be combined with models predicting land-use change to help focus conservation priorities.

  5. Muscle co-contraction modulates damping and joint stability in a three-link bio mechanical limb

    Directory of Open Access Journals (Sweden)

    Stewart eHeitmann

    2012-01-01

    Full Text Available Computational models of neuromotor control require forward models of limb movement that can replicate the natural relationships between muscle activation and joint dynamics without the burdens of excessive anatomical detail. We present a model of a three-link biomechanical limb that emphasizes the dynamics of limb movement within a simplified two-dimensional framework. Muscle co-contraction effects were incorporated into the model by flanking each joint with a pair of antagonist muscles that may be activated independently. Muscle co-contraction is known to alter the damping and stiffness of limb joints without altering net joint torque. Idealized muscle actuators were implemented using the Voigt muscle model which incorporates the parallel elasticity of muscle and tendon but omits series elasticity. The natural force-length-velocity relationships of contractile muscle tissue were incorporated into the actuators using ideal mathematical forms. Numerical stability analysis confirmed that co-contraction of these simplified actuators increased damping in the biomechanical limb consistent with observations of human motor control. Dynamic changes in joint stiffness were excluded by the omission of series elasticity. The analysis also revealed the unexpected finding that distinct stable (bistable equilibrium positions can co-exist under identical levels of muscle co-contraction. We map the conditions under which bistability arises and prove analytically that monostability (equifinality is guaranteed when the antagonist muscles are identical. Lastly we verify these analytic findings in the full biomechanical limb model.

  6. Cape gooseberry (Physalis peruviana) juice as a modulator agent for hepatocellular carcinoma-linked apoptosis and cell cycle arrest.

    Science.gov (United States)

    Hassan, Hanaa A; Serag, Hanaa M; Qadir, Makwan S; Ramadan, Mohamed Fawzy

    2017-10-01

    Cape gooseberry (Physalis peruviana) fruit is highly nutritious with high content of health-promoting compounds including minerals, phenolic compounds, as well as vitamins A and C. Physalis peruviana fruits were used as mutagenic, antispasmodic, anticoagulant, and antileucemis agents. The objective of the present work was to study the role of cape gooseberry juice (CG) as a natural modulator agent for adverse aspects associated with hepatocellular carcinoma (HCC). The results recorded that HCC rats had a significant disturbance in blood indices. An elevation in serum level of the inflammatory (TNF-ά, CRP, and Argenase), hepatic apoptotic markers (P53, Bax, and Caspase 3) and a reduction of Blc2% were recorded in HCC rats. The results exhibited the significant disturbance and arrest in hepatic cell cycle (% of M1: SubG1 phase, M2: G0/1 phase of diploid cycle, M3: S phase, and M4: G2/M phase) as well as liver cell viability status in HCC rats. Numerous histopathological alterations were detected in hepatic tissues of HCC rats such as inflammation, damage of hepatocytes, dilated congested central vein with degenerated endothelial cells and congested blood sinusoids in addition to collagen fibers in hepatocytes and central vein indicating hepatic fibrosis. The tested parameters were little improved upon treatment of HCC rats with Adriamycin (ADR, Doxorubicin is a generic name of a drug). HCC rats received CG showed an improvement in all tested parameters. The effects of CG were through down regulation of p53 expression and up-regulation of Bcl2 domain protected hepatic structure from extensive damage. CG plus ADR exhibited an enhanced antitumor impact in HCC and this combination might have an important value in the treatment of HCC. CG was more effective than ADR, and it has a remarkable role in the management of hepatic disorders besides its success as a chemo-sensitizer for ADR treatment of hepatocellular carcinoma. Copyright © 2017 Elsevier Masson SAS. All rights

  7. Supporting the Creation and Publication of Reviewed and Tested Teaching Modules through the InTeGrate Project

    Science.gov (United States)

    Bruckner, M. Z.; Birnbaum, S. J.; Bralower, T. J.; Egger, A. E.; Fox, S.; Gosselin, D. C.; Iverson, E. A. R.; Manduca, C. A.; Mcconnell, D. A.; Steer, D. N.; Taber, J. J.

    2016-12-01

    InTeGrate is dedicated to providing robust curricular materials that increase Earth literacy among undergraduate students. As of August 2016, 14 modules that use an interdisciplinary approach to teach about Earth-related sustainability issues across the curriculum have been published, and 19 courses and modules are undergoing final revisions. Materials are designed for undergraduate courses and have been tested in a variety of disciplines including geoscience, engineering, humanities, ethics, and Spanish language courses. The materials were developed, tested, revised, and reviewed using a two-year, highly scaffolded process that involves meeting a series of checkpoints, and is supported by a team of experts who provide guidance and formative feedback throughout the process. A series of webinars also supported teams in the development process. Author teams comprise 3-6 faculty members from at least three different institutions. Authors work collaboratively in a templated webspace designed specifically for creating materials, and representatives from the InTeGrate leadership, assessment, and web teams support each group of authors. This support team provides guidance and feedback on content, pedagogy, and web layout as authors develop materials. Authors attend two face-to-face meetings, one at the beginning of the process and another after materials are piloted in authors' classes. These meetings serve to initially orient authors to the development process, including the rubric that will guide their work, and in making revisions following the piloting phase of the project. Authors report that the meetings also provide professional development experience wherein they learn about pedagogy from each other and team leaders. The bulk of the materials development occurs remotely, with teams meeting regularly via teleconference as they follow the project timeline. All materials undergo review against the Materials Design and Refinement Rubric to ensure they meet project

  8. GABAergic Synapses at the Axon Initial Segment of Basolateral Amygdala Projection Neurons Modulate Fear Extinction.

    Science.gov (United States)

    Saha, Rinki; Knapp, Stephanie; Chakraborty, Darpan; Horovitz, Omer; Albrecht, Anne; Kriebel, Martin; Kaphzan, Hanoch; Ehrlich, Ingrid; Volkmer, Hansjürgen; Richter-Levin, Gal

    2017-01-01

    Inhibitory synaptic transmission in the amygdala has a pivotal role in fear learning and its extinction. However, the local circuits formed by GABAergic inhibitory interneurons within the amygdala and their detailed function in shaping these behaviors are not well understood. Here we used lentiviral-mediated knockdown of the cell adhesion molecule neurofascin in the basolateral amygdala (BLA) to specifically remove inhibitory synapses at the axon initial segment (AIS) of BLA projection neurons. Quantitative analysis of GABAergic synapse markers and measurement of miniature inhibitory postsynaptic currents in BLA projection neurons after neurofascin knockdown ex vivo confirmed the loss of GABAergic input. We then studied the impact of this manipulation on anxiety-like behavior and auditory cued fear conditioning and its extinction as BLA related behavioral paradigms, as well as on long-term potentiation (LTP) in the ventral subiculum-BLA pathway in vivo. BLA knockdown of neurofascin impaired ventral subiculum-BLA-LTP. While this manipulation did not affect anxiety-like behavior and fear memory acquisition and consolidation, it specifically impaired extinction. Our findings indicate that modification of inhibitory synapses at the AIS of BLA projection neurons is sufficient to selectively impair extinction behavior. A better understanding of the role of distinct GABAergic synapses may provide novel and more specific targets for therapeutic interventions in extinction-based therapies.

  9. PROJECTING PRINCIPLES OF «MATHEMATICAL AND PHYSICAL BASICS IN INFORMATICS» MODULE AS PART OF A UNIVERSAL BACCALAUREATE PROGRAM

    Directory of Open Access Journals (Sweden)

    E. K. Samerkhanova

    2016-01-01

    Full Text Available This article is a presentation of “Mathematical and Physical Basics in Informatics” Module projected as part of universal baccalaureate model realized in Minin State Pedagogical University, Nizhny Novgorod, within the educational program for an extended group of qualifications “Informatics and Calculating Machines”. Module authors defined a strategy for baccalaureates preparation in the field of informational technology, which is realized due to a bunch of principles: education fundamentalization, learning systematization, activity, integration and student-centration. The principle of education fundamentalization requires consolidation of scientific and methodological preparation of students. The principle of learning systematization guarantees formation of students’ holistic ideology. The principle of integration is directed onto qualitative interdisciplinary conversion based on mutual enrichment of knowledge and skills. The principle of activity considers student personality, its formation and growth with respect to practical activity as a special form of psychical activity. The principle of student-centration is displayed as social-humanistic purpose of the educational process.

  10. State of the Art analysis for the 'SolcelleInverter' project. Optimised design and control of inverter for photovoltaic systems: the AC-module

    Energy Technology Data Exchange (ETDEWEB)

    Baekhoej Kjaer, S.

    2002-02-01

    The 'SolcelleInverter' project starts with this state-of-the-art analysis of 27 different inverter topologies for use in photovoltaic applications. The main concern is the present status for inverters for single solar modules. Technologies for larger clusters of modules are also investigated. The possibility of combining a small decentralised and a big centralised unit is as well investigated. A series of topologies are discovered and this paper will present them. That includes solutions with and without transformers, systems for one or multiple modules, commercial solutions and solutions found in scientific papers and patents. (au)

  11. Linking downhole logging data and clay mineralogy analysis in the ICDP Lake Junín drilling Project, Peru

    Science.gov (United States)

    Pierdominici, S.; Schleicher, A.; Kueck, J.; Rodbell, D. T.; Abbott, M. B.

    2017-12-01

    The lake Junin drilling project, co-funded by the International Continental Drilling Program (ICDP), is located at 4000 m a.s.l. in the tropical Andes of Peru. Several boreholes were drilled with the goal to obtain both high-resolution paleoclimate records from lacustrine sediments and to reconstruct the history of the continental records covering the glacial-interglacial cycles. Lake Junín is characterized by a thick package of lacustrine sediments (> 125 m) deposited at a high rate (0.2 to 1.0 mm yr-1), and it is one of the few lakes in the tropical Andes that is hundreds of thousands of years old with a continuous sedimentation rate preserving a very long and continuous record of past ice age cycles. The boreholes reached a maximum depth of 110.08 m and continuous coring was performed at three sites with 11 boreholes. Additionally, an extensive geophysical downhole logging campaign was performed on five boreholes (1A, 1C, 1D, 2A and 3B) by the Operational Support Group of ICDP. Downhole logging measurements comprise total and spectrum gamma ray, magnetic susceptibility, borehole geometry, temperature, and sonic p-wave velocity. In order to fit the downhole logging depths to the composite profile depths, each borehole was depth-matched with the core data. Interpreting the downhole logging data permits to establish a complete lithological log, to characterize the in-situ physical properties of drilled lacustrine sediments, to determine sedimentary structures and to obtain evidences about palaeoclimatic conditions during up to 200 ka. Th and K values are used as a proxy for a first estimate and characterization of clay content in the sediments, which are present as montmorillonite, smectite, illite, and kaolinite in different amounts. Linking the clay minerals that occur in the core material with the downhole logging data allows assessing the geological history of the lake and the relationship to climate change processes. Additional laboratory analysis will be

  12. The Test Blanket Modules project in Europe: From the strategy to the technical plan over next ten years

    International Nuclear Information System (INIS)

    Poitevin, Y.; Zmitko, M.; Orco, G. dell; Laesser, R.; Diegele, E.; Sundstroem, J.; Boccaccini, L.; Salavy, J.-F.

    2006-01-01

    The testing of Breeding Blanket concepts in ITER is recognized as an essential milestone in the development of a future reactor ensuring tritium self-sufficiency, extraction of high grade heat and electricity production. Europe is currently developing two reference breeding blankets for DEMO reactor specifications that will be tested in ITER: the Helium-Cooled Lithium-Lead (HCLL) blanket which uses the eutectic Pb-15. 7 Li as both breeder and neutron multiplier, and the Helium-Cooled Pebble-Bed (HCPB) blanket which features lithiated ceramic pebbles (Li 4 SiO 4 or Li 2 TiO 3 ) as breeder and beryllium pebbles as neutron multiplier. Both blankets are using the pressurized He technology for heat extraction (8 MPa, inlet/outlet temperature 300/500 o C) and a 9% CrWVTa Reduced Activation Ferritic Martensitic (RAFM) steel as structural material, the EUROFER. Referring to the so called '' fast-track '' EU scenario, those concepts are intended to be tested in ITER, getting the maximum of information required for launching the DEMO blanket design and construction after the first 10 years of ITER operation. For that, the EU has adopted a blanket testing strategy based on the development of Test Blanket Modules (TBMs) that are expected to use DEMO relevant technologies and are designed for each ITER plasma phase to optimize the feedback and to avoid any impact on ITER availability. Following the decision on ITER construction, the EU has reviewed and detailed the fundamental elements for an implementation of the future EU TBMs Project aimed at delivering TBMs Systems to ITER under suitable schedule and acceptance standards. For that the following items have been analyzed in detail and are reported in the present paper: · Impact of the ITER environment (design, standards, schedule, operational scheme) on the TBM systems design and development plan · Project technical plan with focus on the next ten years up to the installation of the first TBMs in ITER · Project risk

  13. A project proposal for implementing intensity modulated radiotherapy (IMRT) for treatment of head and neck tumors

    International Nuclear Information System (INIS)

    Napoles Morales, Misleidy; Garcia Yip, Fernando; Rodriguez Machado, Jorge; Yanes Lopez, Yaima; Pomares Gomez, Yenes; Mena, Yailen

    2009-01-01

    Malignant tumors located in the structures of the head and neck, excluding the skull and its contents, constitute 10% of all cancers, remains the most frequent locations, which correspond to the oral cavity between 40 to 60%. Diagnosed between 60 to 80% in early stages and a 15 to 30% in more advanced forms of the disease. Radiotherapy and surgery are the essential therapeutic tools in the treatment of these tumors planning processes and administration of radiotherapy treatments currently in a situation of rapid and radical change. Since the beginning of radiotherapy to this day the greatest advances in treatment have been linked to a better definition of the tumor irradiation thus get a reduced dose in healthy tissue. The use of radiation, can be severe sequelae affecting quality of life of the patient, organs at risk receiving high dose and advanced technique of IMRT treatment planning and allows treatments shaped fields, especially when the target of radiation is irregular, with fewer side effects by limiting the dose in the tumor tissues and organs at risk and to allow us to increase the doses in the tumor. So we decided to develop a protocol for the implementation of IMRT, taking into account that we have the appropriate equipment, trained staff to develop this technique. (Author)

  14. Low cost solar array project production process and equipment task. A Module Experimental Process System Development Unit (MEPSDU)

    Science.gov (United States)

    1981-01-01

    Technical readiness for the production of photovoltaic modules using single crystal silicon dendritic web sheet material is demonstrated by: (1) selection, design and implementation of solar cell and photovoltaic module process sequence in a Module Experimental Process System Development Unit; (2) demonstration runs; (3) passing of acceptance and qualification tests; and (4) achievement of a cost effective module.

  15. EpiCollect+: linking smartphones to web applications for complex data collection projects [v1; ref status: indexed, http://f1000r.es/3vk

    Directory of Open Access Journals (Sweden)

    David M. Aanensen

    2014-08-01

    Full Text Available Previously, we have described the development of the generic mobile phone data gathering tool, EpiCollect, and an associated web application, providing two-way communication between multiple data gatherers and a project database. This software only allows data collection on the phone using a single questionnaire form that is tailored to the needs of the user (including a single GPS point and photo per entry, whereas many applications require a more complex structure, allowing users to link a series of forms in a linear or branching hierarchy, along with the addition of any number of media types accessible from smartphones and/or tablet devices (e.g., GPS, photos, videos, sound clips and barcode scanning. A much enhanced version of EpiCollect has been developed (EpiCollect+. The individual data collection forms in EpiCollect+ provide more design complexity than the single form used in EpiCollect, and the software allows the generation of complex data collection projects through the ability to link many forms together in a linear (or branching hierarchy. Furthermore, EpiCollect+ allows the collection of multiple media types as well as standard text fields, increased data validation and form logic. The entire process of setting up a complex mobile phone data collection project to the specification of a user (project and form definitions can be undertaken at the EpiCollect+ website using a simple ‘drag and drop’ procedure, with visualisation of the data gathered using Google Maps and charts at the project website. EpiCollect+ is suitable for situations where multiple users transmit complex data by mobile phone (or other Android devices to a single project web database and is already being used for a range of field projects, particularly public health projects in sub-Saharan Africa. However, many uses can be envisaged from education, ecology and epidemiology to citizen science.

  16. Overview of the Last Progresses for the European Test Blanket Modules Projects

    International Nuclear Information System (INIS)

    Salavy, J.-F.; Rampal, G.; Boccaccini, L.V.; Meyder, R.; Neuberger, H.; Laesser, R.; Poitevin, Y.; Zmitko, M.; Rigal, E.

    2006-01-01

    The long-term objective of the EU Breeding Blankets programme is the development of DEMO breeding blankets, which shall assure tritium self-sufficiency, an economically attractive use of the heat produced inside the blankets for electricity generation and a sufficiently high shielding of the superconducting magnets for long time operation. In the short-term so-called DEMO relevant Test Blanket Modules (TBMs) of these breeder blanket concepts shall be designed, manufactured, tested, installed, commissioned and operated in ITER for first tests in a fusion environment. The Helium Cooled Lithium-Lead (HCLL) breeder blanket and the Helium Cooled Pebble Bed (HCPB) concepts are the two breeder blanket lines presently developed by the EU. The main objective of the EU test strategy related to TBMs in ITER is to provide the necessary information for the design and fabrication of breeding blankets for a future DEMO reactor. EU TBMs shall therefore use the same structural and functional materials, apply similar fabrication technologies, and test adequate processes and components. This paper gives an overview of the last progresses in terms of system design, calculations, test program, safety and R-and-D done these last two years in order to cope with the ambitious objective to introduce two EU TBM systems for day-1 of ITER operation. The engineering design of the two systems is mostly concluded and the priority is now on the development and qualification of the fabrication technologies. From calculations point of view, the last modelling efforts related to the thermal-hydraulic of the first wall, the tritium behaviour, and the box thermal and mechanical resistance in accidental conditions are presented. Last features of the TBM and cooling system designs and integration in ITER reactor are highlighted. In particular, this paper also describes the safety and licensing analyses performed for each concept to be able to include the TBM systems in the ITER preliminary safety report

  17. A coherent free space optical link for long distance clock comparison, navigation, and communication: The Mini-Doll project

    Science.gov (United States)

    Djerroud, K.; Samain, E.; Clairon, A.; Acef, O.; Man, N.; Lemonde, P.; Wolf, P.

    2017-11-01

    We describe the realization of a 5 km free space coherent optical link through the turbulent atmosphere between a telescope and a ground target. We present the phase noise of the link, limited mainly by atmospheric turbulence and mechanical vibrations of the telescope and the target. We discuss the implications of our results for applications, with particular emphasis on optical Doppler ranging to satellites and long distance frequency transfer.

  18. Castration modulates singing patterns and electrophysiological properties of RA projection neurons in adult male zebra finches

    Directory of Open Access Journals (Sweden)

    Songhua Wang

    2014-04-01

    Full Text Available Castration can change levels of plasma testosterone. Androgens such as testosterone play an important role in stabilizing birdsong. The robust nucleus of the arcopallium (RA is an important premotor nucleus critical for singing. In this study, we investigated the effect of castration on singing patterns and electrophysiological properties of projection neurons (PNs in the RA of adult male zebra finches. Adult male zebra finches were castrated and the changes in bird song assessed. We also recorded the electrophysiological changes from RA PNs using patch clamp recording. We found that the plasma levels of testosterone were significantly decreased, song syllable’s entropy was increased and the similarity of motif was decreased after castration. Spontaneous and evoked firing rates, membrane time constants, and membrane capacitance of RA PNs in the castration group were lower than those of the control and the sham groups. Afterhyperpolarization AHP time to peak of spontaneous action potential (AP was prolonged after castration.These findings suggest that castration decreases song stereotypy and excitability of RA PNs in male zebra finches.

  19. Using a portfolio of evidence in a community-based project module: reflection in perspective

    Directory of Open Access Journals (Sweden)

    PH van der Westhuizen

    2014-01-01

    Full Text Available Community-based learning is a relatively new field in South Africa. It has only been extensively included in academic programmes at universities for about fifteen years.Students have to make a positive contribution to individuals in their communities (Dukhan 2008:21 and develop a combination of knowledge, skills, values and motivation in order to make a difference, and to promote the quality of life in a community (O Connor 2006: 52.Too often assessment reflects on a single quantitative measure or symbol to indicate a level of achievement. This aggregate does not, however, indicate the student‟s particular weaknesses and strengths, and whether or not he or she possesses competencies in a specific aspect. A more objective method/procedure of reporting assessment on levels of achievement and competency obtained is the compilation of a portfolio. The main aim of this paper is to provide some guidelines for the compilation and implementation of portfolios as a tool in authentic assessment for the student, but also acts as a document that would guide a community into the sustainability of the project.

  20. PyChimera: use UCSF Chimera modules in any Python 2.7 project.

    Science.gov (United States)

    Rodríguez-Guerra Pedregal, Jaime; Maréchal, Jean-Didier

    2018-05-15

    UCSF Chimera is a powerful visualization tool remarkably present in the computational chemistry and structural biology communities. Built on a C++ core wrapped under a Python 2.7 environment, one could expect to easily import UCSF Chimera's arsenal of resources in custom scripts or software projects. Nonetheless, this is not readily possible if the script is not executed within UCSF Chimera due to the isolation of the platform. UCSF ChimeraX, successor to the original Chimera, partially solves the problem but yet major upgrades need to be undergone so that this updated version can offer all UCSF Chimera features. PyChimera has been developed to overcome these limitations and provide access to the UCSF Chimera codebase from any Python 2.7 interpreter, including interactive programming with tools like IPython and Jupyter Notebooks, making it easier to use with additional third-party software. PyChimera is LGPL-licensed and available at https://github.com/insilichem/pychimera. jaime.rodriguezguerra@uab.cat or jeandidier.marechal@uab.cat. Supplementary data are available at Bioinformatics online.

  1. Hippocampal Ghrelin-positive neurons directly project to arcuate hypothalamic and medial amygdaloid nuclei. Could they modulate food-intake?

    Science.gov (United States)

    Russo, Cristina; Russo, Antonella; Pellitteri, Rosalia; Stanzani, Stefania

    2017-07-13

    Feeding is a process controlled by a complex of associations between external and internal stimuli. The processes that involve learning and memory seem to exert a strong control over appetite and food intake, which is modulated by a gastrointestinal hormone, Ghrelin (Ghre). Recent studies claim that Ghre is involved in cognitive and neurobiological mechanisms that underlie the conditioning of eating behaviors. The expression of Ghre increases in anticipation of food intake based on learned behaviors. The hippocampal Ghre-containing neurons neurologically influence the orexigenic hypothalamus and consequently the learned feeding behavior. The CA1 field of Ammon's horn of the hippocampus (H-CA1) constitutes the most important neural substrate to control both appetitive and ingestive behavior. It also innervates amygdala regions that in turn innervate the hypothalamus. A recent study also implies that Ghre effects on cue-potentiated feeding behavior occur, at the least, via indirect action on the amygdala. In the present study, we investigate the neural substrates through which endogenous Ghre communicates conditioned appetite and feeding behavior within the CNS. We show the existence of a neural Ghre dependent pathway whereby peripherally-derived Ghre activates H-CA1 neurons, which in turn activate Ghre-expressing hypothalamic and amygdaloid neurons to stimulate appetite and feeding behavior. To highlight this pathway, we use two fluorescent retrograde tracers (Fluoro Gold and Dil) and immunohistochemical detection of Ghre expression in the hippocampus. Triple fluorescent-labeling has determined the presence of H-CA1 Ghre-containing collateralized neurons that project to the hypothalamus and amygdala monosynaptically. We hypothesize that H-Ghre-containing neurons in H-CA1 modulate food-intake behavior through direct pathways to the arcuate hypothalamic nucleus and medial amygdaloid nucleus. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Dynamic link: user's manual

    International Nuclear Information System (INIS)

    Harada, Hiroo; Asai, Kiyoshi; Kihara, Kazuhisa.

    1981-09-01

    The purpose of dynamic link facility is to link a load module dynamically only when it is used in execution time. The facility is very useful for development, execution and maintenance of a large scale computer program which is too big to be saved as one load module in main memory, or it is poor economy to save it due to many unused subroutines depending on an input. It is also useful for standardization and common utilization of programs. Standard usage of dynamic link facility of FACOM M-200 computer system, a software tool which analyzes the effect of dynamic link facility and application of dynamic link to nuclear codes are described. (author)

  3. Alignment Methods Developed for the Validation of the Thermal and Mechanical Behaviour of the Two Beam Test Modules for the CLIC Project

    CERN Document Server

    Mainaud Durand, Helene; Sosin, Mateusz; Rude, Vivien

    2014-01-01

    CLIC project will consist of more than 20 000 two meters long modules. A test setup made of three modules is being built at CERN to validate the assembly and integration of all components and technical systems and to validate the short range strategy of pre-alignment. The test setup has been installed in a room equipped with a sophisticated system of ventilation able to reproduce the environmental conditions of the CLIC tunnel. Some of the components have been equipped with electrical heaters to simulate the power dissipation, combined with a water cooling system integrated in the RF components. Using these installations, to have a better understanding of the thermal and mechanical behaviour of a module under different operation modes, machine cycles have been simulated; the misalignment of the components and their supports has been observed. This paper describes the measurements methods developed for such a project and the results obtained.

  4. Assessing the Need for an On-Line Educational Module for Volunteer Leaders on Bio-Security in Washington State 4-H Livestock Projects

    Science.gov (United States)

    Stevenson, Jill L.; Moore, Dale A.; Newman, Jerry; Schmidt, Janet L.; Smith, Sarah M.; Smith, Jean; Kerr, Susan; Wallace, Michael; BoyEs, Pat

    2011-01-01

    4-H livestock projects present disease transmission risks that can be reduced by the use of bio-security practices. The responsibility of teaching bio-security to youth belongs primarily to volunteer leaders, who may not be aware of the importance of these practices. A needs assessment for an online educational module about bio-security revealed…

  5. What Research Says about Effective Teaching for Promoting Achievement and Positive Attitudes in Students. An Instructional Module Prepared for Undergraduate Teacher Education in the RAFT Project.

    Science.gov (United States)

    Handley, Herbert M., Ed.

    This module, developed by the Research Applications for Teaching (RAFT) project, was written to introduce the preservice teacher to the research base for effective teaching. Particular attention was given to the characteristics of teachers and teaching found in research literature to be associated with achievement and the development of positive…

  6. Simplified pilot module development and testing within the ATLAS PanDA Pilot 2.0 Project

    CERN Document Server

    Drizhuk, Daniil; The ATLAS collaboration; Nilsson, Paul

    2016-01-01

    The Production and Distributed Analysis (PanDA) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at the LHC data processing scale. The PanDA pilot is one of the major components in the PanDA system. It runs on a worker node and takes care of setting up the environment, fetching and pushing data to storage, getting jobs from the PanDA server and executing them. The original PanDA Pilot was designed over 10 years ago and has since then grown organically. Large parts of the original pilot code base are now getting old and are difficult to maintain. Incremental changes and refactoring have been pushed to the limit, and the time is now right for a fresh start, informed by a decade of experience, with the PanDA Pilot 2.0 Project. To create a testing environment for module development and automated unit and functional testing for next generation pilot tasks, a simple pilot version was developed. It resembles the basic workf...

  7. Operative Links

    DEFF Research Database (Denmark)

    Wistoft, Karen; Højlund, Holger

    2012-01-01

    and have been the object of great expectations concerning the ability to incorporate health concerns into every welfare area through health promotion strategies. The paper draws on results and analyses of a collective research project funded by the Danish National Research Council and carried out...... links' that indicate cooperative levels which facilitate a creative and innovative effort in disease prevention and health promotion targeted at children and adolescents - across traditional professional boundaries. It is proposed that such links are supported by network structures, shared semantics...

  8. Predicting future US water yield and ecosystem productivity by linking an ecohydrological model to WRF dynamically downscaled climate projections

    Science.gov (United States)

    S. Sun; Ge Sun; Erika Cohen Mack; Steve McNulty; Peter Caldwell; K. Duan; Y. Zhang

    2015-01-01

    Quantifying the potential impacts of climate change on water yield and ecosystem productivity (i.e., carbon balances) is essential to developing sound watershed restoration plans, and climate change adaptation and mitigation strategies. This study links an ecohydrological model (Water Supply and Stress Index, WaSSI) with WRF (Weather Research and Forecasting Model)...

  9. Energy Deposition and DPA in the Superconducting Links for the HILUMI LHC Project at the LHC Interaction Points

    CERN Document Server

    AUTHOR|(CDS)2092158; Broggi, Francesco; Santini, C; Ballarino, Amalia; Cerutti, Francesco; Esposito, Luigi Salvatore

    2015-01-01

    In the framework of the upgrade of the LHC machine, the powering of the LHC magnets foresees the removal of the power converters and distribution feedboxes from the tunnel and its location at the surface[1]. The Magnesium Diboride (MgB2) connecting lines in the tunnel will be exposed to the debris from 7+7 TeV p-p interaction. The Superconducting (SC) Links will arrive from the surface to the tunnel near the separation dipole, at about 80 m from the Interaction Point at IP1 and IP5. The Connection Box (where the cables of the SC Links are connected to the NbTi bus bar) will be close to the beam pipe. The debris and its effect on the MgB2 SC links in the connection box (energy deposition and displacement per atom) are presented. The effect of thermal neutrons on the Boron consumption and the contribution of the lithium nucleus and the alpha particle on the DPA are evaluated. The results are normalized to an integrated luminosity of 3000 fb-1, value that represents the LHC High Luminosity lifetime. The dose de...

  10. Linking Effective Project Management to Business Strategy in Oil and Gas Industry through Decision-making Processes

    Science.gov (United States)

    Adeleke, Adeyinka

    The construction project in the oil and gas industry covers the entire spectrum of hydrocarbon production from the wellhead (upstream) to downstream facilities. In each of these establishments, the activities in a construction project include: consulting, studies, front-end engineering, detail engineering, procurement, program management, construction, installation, commissioning and start-up. Efficient management of each of the activities involved in construction projects is one of the driving forces for the successful completion of the project. Optimizing the crucial factors in project management during each phase of a project in an oil and gas industry can assist managers to maximize the use of available resources and drive the project to successful conclusions. One of these factors is the decision-making process in the construction project. Current research effort investigated the relationship between decision-making processes and business strategy in oil and gas industry using employee surveys. I recruited employees of different races, age group, genders, and years of experience in order understand their influence on the implementation of the decision-making process in oil and gas industry through a quantitative survey. Decision-making was assessed using five decision measures: (a) rational, (b) intuitive, (c) dependent, (d) avoidant, and (e) spontaneous. The findings indicated gender, age, years of work experience and job titles as primary variables with a negative relationship with decision-making approach for employees working in a major oil and gas industry. The study results revealed that the two most likely decision-making methods in oil and gas industry include: making a decision in a logical and systematic way and seek assistance from others when making a decision. Additionally, the two leading management approaches to decision-making in the oil and gas industry include: decision analysis is part of organization culture and management is committed to

  11. Project Roadkill: Linking European Hare vehicle collisions with landscape-structure using datasets from citizen scientists and professionals

    Science.gov (United States)

    Stretz, Carina; Heigl, Florian; Steiner, Wolfgang; Bauer, Thomas; Suppan, Franz; Zaller, Johann G.

    2015-04-01

    Road networks can implicate lots of negative effects for wildlife. One of the most important indication for strong landscape fragmentation are roadkills, i.e. collisions between motorised vehicles and wild animals. A species that is often involved in roadkills is the European hare (Lepus europaeus). European hare populations are in decline throughout Europe since the 1960s and classified as "potentially endangered" in the Red Data Book of Austria. Therefore, it is striking that in the hunting year 2013/14, 19,343 hares were killed on Austrian roads translating to 53 hare roadkills each day, or rather about two per hour. We hypothesized, that (I) hare-vehicle-collisions occur as an aggregation of events (hotspot), (II) the surrounding landscape influences the number of roadkilled hares and (III) roadkill data from citizen science projects and data from professionals (e.g. hunters, police) are convergent. Investigations on the surrounding landscape of the scenes of accidents will be carried out using land cover data derived from Landsat satellite images. Information on road kills are based on datasets from two different sources. One dataset stems from the citizen science project "Roadkill" (www.citizen-science.at/roadkill) where participants report roadkill findings via a web application. The second dataset is from a project where roadkill data were collected by the police and by hunters. Besides answering our research questions, findings of this project also allow the location of dangerous roadkill hotspots for animals and could be implemented in nature conservation actions.

  12. The hELENa project - I. Stellar populations of early-type galaxies linked with local environment and galaxy mass

    NARCIS (Netherlands)

    Sybilska, A.; Lisker, T.; Kuntschner, H.; Vazdekis, A.; van de Ven, G.; Peletier, R.; Falcón-Barroso, J.; Vijayaraghavan, R.; Janz, J.

    2017-01-01

    We present the first in a series of papers in The role of Environment in shaping Low-mass Early-type Nearby galaxies (hELENa) project. In this paper, we combine our sample of 20 low-mass early types (dEs) with 258 massive early types (ETGs) from the ATLAS3D survey - all observed with the SAURON

  13. The European DISABKIDS project: development of seven condition-specific modules to measure health related quality of life in children and adolescents

    Directory of Open Access Journals (Sweden)

    Bullinger Monika

    2005-11-01

    Full Text Available Abstract Background The European DISABKIDS project aims to enhance the Health Related Quality of Life (HRQoL of children and adolescents with chronic medical conditions and their families. We describe the development of the seven cross-nationally tested condition-specific modules of the European DISABKIDS HRQoL instrument in a population of children and adolescents. The condition-specific modules are intended for use in conjunction with the DISABKIDS chronic generic module. Methods Focus groups were used to construct the pilot version of the DISABKIDS condition-specific HRQoL modules for asthma, juvenile idiopathic arthritis, atopic dermatitis, cerebral palsy, cystic fibrosis, diabetes and epilepsy. Analyses were conducted on pilot test data in order to construct field test versions of the modules. A series of factor analyses were run, first, to determine potential structures for each condition-specific module, and, secondly, to select a reduced number of items from the pilot test to be included in the field test. Post-field test analyses were conducted to retest the domain structure for the final DISABKIDS condition-specific modules. Results The DISABKIDS condition-specific modules were tested in a pilot study of 360 respondents, and subsequently in a field test of 1152 respondents in 7 European countries. The final condition-specific modules consist of an 'Impact' domain and an additional domain (e.g. worry, stigma, treatment with between 10 to 12 items in total. The Cronbach's alpha of the final domains was found to vary from 0.71 to 0.90. Conclusion The condition-specific modules of the DISABKIDS instrument were developed through a step-by-step process including cognitive interview, clinical expertise, factor analysis, correlations and internal consistency. A cross-national pilot and field test were necessary to collect these data. In general, the internal consistency of the domains was satisfactory to high. In future, the DISABKIDS

  14. Teaching Concepts to Young Children Through Cultural Cooking Experiences. Bilingual/Bicultural Child Development Associate Pilot Project: Module XIV.

    Science.gov (United States)

    Smith, Teresa R.

    This Child Development Associate (CDA) module, the fourteenth in a series of 16, suggests ways concepts can be taught by involving preschool children in carefully planned classroom cooking activities. Designed for bilingual/bicultural preschool teacher trainees, the module provides tips on food preparation as a learning experience. Required…

  15. Residential photovoltaic module and array requirement study. Low-Cost Solar Array Project engineering area. Final report appendices

    Energy Technology Data Exchange (ETDEWEB)

    1979-06-01

    This volume contains the appendices to a study to identify design requirements for photovoltaic modules and arrays used in residential applications. Appendices include: (1) codes, standards, and manuals of accepted practice-definition and importance; (2) regional code variations-impact; (3) model and city codes-review; (4) National Electric Code (NEC)-review; (5) types of standards-definition and importance; (6) federal standards-review; (7) standards review method; (8) manuals of accepted practice; (9) codes and referenced standards-summary; (10) public safety testing laboratories; (11) insurance review; (12) studies approach; (13) mounting configurations; (14) module/panel size and shape cost analysis; (15) grounding, wiring, terminal and voltage studies; (16) array installation cost summary; (17) photovoltaic shingle/module comparison; (18) retrofit application; (19) residential photovoltaic module performance criteria; (20) critique of JPL's solar cell module design and test specifications for residential applications; and (21) CSI format specification. (WHK)

  16. A digital multi-channel spectroscopy system with 100 MHz flash ADC module for the GENIUS-TF and GENIUS projects

    OpenAIRE

    Kihm, T.; Bobrakov, V. F.; Klapdor-Kleingrothaus, H. V.

    2003-01-01

    In this paper we will present the first results of applying a digital processing technology in low-level gamma spectroscopy with HPGE detectors. An experimental gamma spectrometer using Flash ADC module is built and tested. The test system is now under development and shows major advantages over the traditional analog technologies. It will be installed for the GENIUS-TF and GENIUS projects in Gran-Sasso in early 2003.

  17. A digital multi-channel spectroscopy system with 100 MHz flash ADC module for the GENIUS-TF and GENIUS projects

    International Nuclear Information System (INIS)

    Kihm, T.; Bobrakov, V.F.; Klapdor-Kleingrothaus, H.V.

    2003-01-01

    In this paper we present the first results of applying a digital processing technology in low-level gamma spectroscopy with HPGE detectors. An experimental gamma spectrometer using Flash ADC module is built and tested. The test system is now under development and shows major advantages over the traditional analog technologies. It will be installed for the GENIUS-TF and GENIUS projects in Gran-Sasso in early 2003

  18. The hELENa project - I. Stellar populations of early-type galaxies linked with local environment and galaxy mass

    OpenAIRE

    Sybilska, A.; Lisker, T.; Kuntschner, H.; Vazdekis, A.; van de Ven, G.; Peletier, R.; Falcón-Barroso, J.; Vijayaraghavan, R.; Janz, J.

    2017-01-01

    We present the first in a series of papers in T$h$e role of $E$nvironment in shaping $L$ow-mass $E$arly-type $N$earby g$a$laxies (hELENa) project. In this paper we combine our sample of 20 low-mass early types (dEs) with 258 massive early types (ETGs) from the ATLAS$^{\\mathrm{3D}}$ survey - all observed with the SAURON integral field unit (IFU) - to investigate early-type galaxies' stellar population scaling relations and the dependence of the population properties on local environment, exten...

  19. Experimental demonstration of real-time adaptively modulated DDO-OFDM systems with a high spectral efficiency up to 5.76bit/s/Hz transmission over SMF links.

    Science.gov (United States)

    Chen, Ming; He, Jing; Tang, Jin; Wu, Xian; Chen, Lin

    2014-07-28

    In this paper, a FPGAs-based real-time adaptively modulated 256/64/16QAM-encoded base-band OFDM transceiver with a high spectral efficiency up to 5.76bit/s/Hz is successfully developed, and experimentally demonstrated in a simple intensity-modulated direct-detection optical communication system. Experimental results show that it is feasible to transmit a raw signal bit rate of 7.19Gbps adaptively modulated real-time optical OFDM signal over 20km and 50km single mode fibers (SMFs). The performance comparison between real-time and off-line digital signal processing is performed, and the results show that there is a negligible power penalty. In addition, to obtain the best transmission performance, direct-current (DC) bias voltage for MZM and launch power into optical fiber links are explored in the real-time optical OFDM systems.

  20. Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding in vitro and links PrP function and dysfunction.

    Directory of Open Access Journals (Sweden)

    James F Graham

    Full Text Available Transmissible spongiform encephalopathies are characterised by widespread deposition of fibrillar and/or plaque-like forms of the prion protein. These aggregated forms are produced by misfolding of the normal prion protein, PrP(C, to the disease-associated form, PrP(Sc, through mechanisms that remain elusive but which require either direct or indirect interaction between PrP(C and PrP(Sc isoforms. A wealth of evidence implicates other non-PrP molecules as active participants in the misfolding process, to catalyse and direct the conformational conversion of PrP(C or to provide a scaffold ensuring correct alignment of PrP(C and PrP(Sc during conversion. Such molecules may be specific to different scrapie strains to facilitate differential prion protein misfolding. Since molecular cofactors may become integrated into the growing protein fibril during prion conversion, we have investigated the proteins contained in prion disease-specific deposits by shotgun proteomics of scrapie-associated fibrils (SAF from mice infected with 3 different strains of mouse-passaged scrapie. Concomitant use of negative control preparations allowed us to identify and discount proteins that are enriched non-specifically by the SAF isolation protocol. We found several proteins that co-purified specifically with SAF from infected brains but none of these were reproducibly and demonstrably specific for particular scrapie strains. The α-chain of Na(+/K(+-ATPase was common to SAF from all 3 strains and we tested the ability of this protein to modulate in vitro misfolding of recombinant PrP. Na(+/K(+-ATPase enhanced the efficiency of disease-specific conversion of recombinant PrP suggesting that it may act as a molecular cofactor. Consistent with previous results, the same protein inhibited fibrillisation kinetics of recombinant PrP. Since functional interactions between PrP(C and Na(+/K(+-ATPase have previously been reported in astrocytes, our data highlight this molecule as

  1. Characterization of Mechanical Properties of MgB$_2$ Conductor for the Superconducting Link Project at CERN

    CERN Document Server

    Sugano, M; Bartova, B; Bjoerstad, R; Scheuerlein, C; Grasso, G

    2015-01-01

    In the framework of high luminosity upgrade of Large Hadron Collider at CERN, superconducting links are being developed. MgB2 wire is a candidate conductor for use in high-current cables. Mechanical properties of this material are of key importance for the definition of the cable design and operating conditions. In this study, we evaluated the Young's modulus of MgB2 filaments extracted from ex situ processed composite wires. The wires were produced in unit lengths of about 1 km and used in high-current cables. Single fiber tensile test was carried out on filaments composed of MgB2, Nb barrier, and Nb-Ni reaction layer. From the unloading modulus of filament specimens measured with different gauge lengths, the Young's modulus of composite filaments extracted from two different strands was determined to be 114 and 122 GPa at room temperature, respectively. By using the rule-of-mixture, the Young's modulus of MgB2 was estimated to be lower than that reported for highly dense MgB2 bulks. The reason for such diff...

  2. Projectables

    DEFF Research Database (Denmark)

    Rasmussen, Troels A.; Merritt, Timothy R.

    2017-01-01

    CNC cutting machines have become essential tools for designers and architects enabling rapid prototyping, model-building and production of high quality components. Designers often cut from new materials, discarding the irregularly shaped remains. We introduce ProjecTables, a visual augmented...... reality system for interactive packing of model parts onto sheet materials. ProjecTables enables designers to (re)use scrap materials for CNC cutting that would have been previously thrown away, at the same time supporting aesthetic choices related to wood grain, avoiding surface blemishes, and other...... relevant material properties. We conducted evaluations of ProjecTables with design students from Aarhus School of Architecture, demonstrating that participants could quickly and easily place and orient model parts reducing material waste. Contextual interviews and ideation sessions led to a deeper...

  3. Commercial/industrial photovoltaic module and array requirement study. Low-cost solar array project engineering area

    Science.gov (United States)

    1981-01-01

    Design requirements for photovoltaic modules and arrays used in commercial and industrial applications were identified. Building codes and referenced standards were reviewed for their applicability to commercial and industrial photovoltaic array installation. Four general installation types were identified - integral (replaces roofing), direct (mounted on top of roofing), stand-off (mounted away from roofing), and rack (for flat or low slope roofs, or ground mounted). Each of the generic mounting types can be used in vertical wall mounting systems. This implies eight mounting types exist in the commercial/industrial sector. Installation costs were developed for these mounting types as a function of panel/module size. Cost drivers were identified. Studies were performed to identify optimum module shapes and sizes and operating voltage cost drivers. The general conclusion is that there are no perceived major obstacles to the use of photovoltaic modules in commercial/industrial arrays.

  4. Scenarios, policies and impacts for the linked transport and energy systems. Results of the European TRIAS project

    Energy Technology Data Exchange (ETDEWEB)

    Schade, Wolfgang; Helfrich, Nicki [Fraunhofer-Institut fuer Systemtechnik und Innovationsforschung (ISI), Karlsruhe (Germany); Krail, Michael [Karlsruhe Univ. (T.H.) (Germany). Inst. fuer Wirtschaftspolitik und Wirtschaftsforschung; Fiorello, Davide; Fermi, Francesca [TRT Trasporti e Territori, Milan (Italy); Schade, Burkhard [European Commission Seville (ES). Institute for Prospective Technological Studies (IPTS)

    2008-07-01

    High oil prices and the growing awareness that this will not be a temporary but a permanent situation fosters the search for alternative fuels and new technologies to propel the transport system, which, so far, in Europe depends to more than 96% on fossil fuels. Two of these alternatives would be hydrogen and biofuels that both can be generated from a number of different sources including a number of non-fossil and renewable sources. The TRIAS project combined four models (ASTRA, POLES, VACLAV, Regio-SUSTAIN) to analyse the impacts of different policies that would foster the diffusion of alternative fuels into the transport system. The impact analysis covers the fields of transport, energy, environment, technology and economy. The basic conclusions that can be drawn are that such policies, if they are formulated in an appropriate manner, could stimulate investments and economic development on the one hand and on the other hand would have the potential to generate positive impacts in terms of reductions of CO{sub 2} emissions and increase of security of energy supply due to reduced imports of fossil fuels and the use of a greater diversity of fuels for transport. (orig.)

  5. Extending the Linear Modulation Range to the Full Base Speed Using a Single DC-Link Multilevel Inverter With Capacitor-Fed H-Bridges for IM Drives

    DEFF Research Database (Denmark)

    Rahul, Arun; Pramanick, Sumit; Kaarthik, R. Sudharshan

    2017-01-01

    In this paper, a new space vector pulse width modulation method to extend the linear modulation range of a cascaded five level inverter topology with a single dc supply is presented. Using this method, the inverter can be controlled linearly and the peak phase fundamental output voltage of the in......In this paper, a new space vector pulse width modulation method to extend the linear modulation range of a cascaded five level inverter topology with a single dc supply is presented. Using this method, the inverter can be controlled linearly and the peak phase fundamental output voltage...... of the inverter can be increased from 0.577 to 0.637Vdc without increasing the dc bus voltage and without exceeding the induction motor voltage rating. This new technique makes use of cascaded inverter pole voltage redundancy and property of the space vector structure for its operation. Using this, the induction...

  6. Assessment of Ocean Wave Model used to Analyze the Constellation Program (CxP) Orion Project Crew Module Water Landing Conditions

    Science.gov (United States)

    Smith, Bryan K.; Bouchard, Richard; Teng, Chung-Chu; Dyson, Rodger; Jenson, Robert; OReilly, William; Rogers, Erick; Wang, David; Volovoi, Vitali

    2009-01-01

    Mr. Christopher Johnson, NASA's Systems Manager for the Orion Project Crew Module (CM) Landing and Recovery at the Johnson Space Center (JSC), and Mr. James Corliss, Project Engineer for the Orion CM Landing System Advanced Development Project at the Langley Research Center (LaRC) requested an independent assessment of the wave model that was developed to analyze the CM water landing conditions. A NASA Engineering and Safety Center (NESC) initial evaluation was approved November 20, 2008. Mr. Bryan Smith, NESC Chief Engineer at the NASA Glenn Research Center (GRC), was selected to lead this assessment. The Assessment Plan was presented and approved by the NESC Review Board (NRB) on December 18, 2008. The Assessment Report was presented to the NRB on March 12, 2009. This document is the final Assessment Report.

  7. Development, Implementation, and Assessment of Climate Curricular Materials for Introductory Undergraduates: Lessons Learned from the InTeGrate Project's Climate of Change Module

    Science.gov (United States)

    Walker, B.; Fadem, C. M.; Shellito, L. J.

    2014-12-01

    Designing climate change curricular materials suitable for wide adoption across institutions and academic disciplines (including those outside of the geosciences) requires collaboration among faculty at different types of institutions and consideration of a variety of student populations, learning styles, and course formats. The Interdisciplinary Teaching of Geoscience for a Sustainable Future (InTeGrate) project, an NSF STEP Center program, provides opportunities for faculty to develop 2-3 week teaching modules to engage students in understanding the intersections between geoscience topics and societal issues. From 2012-2014, a team of 3 faculty from a liberal arts college, comprehensive university, and community college developed, implemented, assessed, and revised a 2-3 week module for introductory undergraduates entitled "Climate of change: interactions and feedbacks between water, air, and ice". The module uses authentic atmosphere, ocean, and cryosphere data from several regions to illustrate how climate impacts human societies and that the climate system has interacting components complicated by feedbacks, uncertainties, and human behavioral decisions. Students also consider past and present human adaptations to climate fluctuations. The module was piloted in introductory geology, meteorology, and oceanography courses during the 2012-2013 academic year, during which time formative and summative assessments were administered and used to modify the curricular materials. We will provide an overview of the module's content, instructional strategies involved in implementing the module, and methods of formative and summative assessment. We will also report on lessons learned during the development, piloting, revision, and publishing process, the importance of fostering partnerships between faculty from different institution types, and design approaches that promote widespread adoption of climate curricular materials.

  8. Linking satellite ICT application businesses with regional innovation centers and investors: The EC “INVESaT” project

    Science.gov (United States)

    Ghiron, Florence; Kreisel, Joerg

    2009-09-01

    In the sector of information and communication technologies (ICT), whether in the USA, Japan, or Europe, innovative services are already in use, based on large-scale space-based infrastructure investments. Such systems are e.g. earth observation, telecommunication, and navigation, timing and positioning satellites. In combination with the advent of powerful handheld terminals and the demand for ubiquitous services, it is expected that info-mobility applications will reveal new sources of business in the years ahead, using in particular the Earth observation and future GALILEO systems to position any feature or user anywhere in the world within a few meter accuracy. Hence, satellite-based capabilities provide new and unique opportunities for economic stimulation and development. Many incubators and innovation centers in Europe have already grasped this growth potential. Yet, for many European players business growth appears below expectations compared to developments in the USA following the launch of GPS (Global Positioning System). Europe still has to overcome intrinsic barriers to seize these new business opportunities faster and with more visible economic impact by leveraging on SMEs and regional innovation centers to expand the commercial utilization of satellite capabilities and mobilization of appropriate financial resources. The paper elaborates on the INVESat project (funded by the EuropeInnova—European Commission), which aims at bridging the gap between Innovative enterprises and financial In VEstors in the emerging markets of SaTellite applications. The critical success factors required to stimulate and support more efficiently investments in this bread of innovative services will also be highlighted.

  9. The hELENa project - I. Stellar populations of early-type galaxies linked with local environment and galaxy mass

    Science.gov (United States)

    Sybilska, A.; Lisker, T.; Kuntschner, H.; Vazdekis, A.; van de Ven, G.; Peletier, R.; Falcón-Barroso, J.; Vijayaraghavan, R.; Janz, J.

    2017-09-01

    We present the first in a series of papers in The role of Environment in shaping Low-mass Early-type Nearby galaxies (hELENa) project. In this paper, we combine our sample of 20 low-mass early types (dEs) with 258 massive early types (ETGs) from the ATLAS3D survey - all observed with the SAURON integral field unit - to investigate early-type galaxies' stellar population scaling relations and the dependence of the population properties on local environment, extended to the low-σ regime of dEs. The ages in our sample show more scatter at lower σ values, indicative of less massive galaxies being affected by the environment to a higher degree. The shape of the age-σ relations for cluster versus non-cluster galaxies suggests that cluster environment speeds up the placing of galaxies on the red sequence. While the scaling relations are tighter for cluster than for the field/group objects, we find no evidence for a difference in average population characteristics of the two samples. We investigate the properties of our sample in the Virgo cluster as a function of number density (rather than simple clustrocentric distance) and find that dE ages correlate with the local density such that galaxies in regions of lower density are younger, likely because they are later arrivals to the cluster or have experienced less pre-processing in groups, and consequently used up their gas reservoir more recently. Overall, dE properties correlate more strongly with density than those of massive ETGs, which was expected as less massive galaxies are more susceptible to external influences.

  10. Project W-026, Waste Receiving and Processing (WRAP) Facility Module 1: Maximum possible fire loss (MPFL) decontamination and cleanup estimates. Revision 1

    International Nuclear Information System (INIS)

    Hinkle, A.W.; Jacobsen, P.H.; Lucas, D.R.

    1994-01-01

    Project W-026, Waste Receiving and Processing (WRAP) Facility Module 1, a 1991 Line Item, is planned for completion and start of operations in the spring of 1997. WRAP Module 1 will have the capability to characterize and repackage newly generated, retrieved and stored transuranic (TRU), TRU mixed, and suspect TRU waste for shipment to the Waste isolation Pilot Plant (WIPP). In addition, the WRAP Facility Module 1 will have the capability to characterize low-level mixed waste for treatment in WRAP Module 2A. This report documents the assumptions and cost estimates for decontamination and clean-up of a maximum possible fire loss (MPFL) as defined by DOE Order 5480.7A, FIRE PROTECTION. The Order defines MPFL as the value of property, excluding land, within a fire area, unless a fire hazards analysis demonstrates a lesser (or greater) loss potential. This assumes failure of both automatic fire suppression systems and manual fire fighting efforts. Estimates were developed for demolition, disposal, decontamination, and rebuilding. Total costs were estimated to be approximately $98M

  11. Project Engage: Snowball Sampling and Direct Recruitment to Identify and Link Hard-to-Reach HIV-Infected Persons Who Are Out of Care.

    Science.gov (United States)

    Wohl, Amy Rock; Ludwig-Barron, Natasha; Dierst-Davies, Rhodri; Kulkarni, Sonali; Bendetson, Jesse; Jordan, Wilbert; Bolan, Robert; Smith, Terry; Cunningham, William; Pérez, Mario J

    2017-06-01

    Innovative strategies are needed to identify and link hard-to-find persons living with HIV (PLWH) who are out of care (OOC). Project Engage, a health department-based project in Los Angeles County, used a mixed-methods approach to locate and provide linkage for PLWH who have limited contact with HIV medical and nonmedical services. Incentivized social network recruitment (SNR) and direct recruitment (DR) was used to identify eligible OOC alters for a linkage intervention that included HIV clinic selection, appointment and transportation support, reminder calls/texts, and clinic navigation. Between 2012 and 2015, 112 alters were identified using SNR (n = 74) and DR (n = 38). Most alters were male (80%), African American (38%), and gay (60%). Sizable percentages were homeless (78%), had engaged in sex work (32%) in the previous 6 months, had injected drugs (47%), were incarcerated in the previous 12 months (50%), and had only received HIV care during the previous 5 years while incarcerated (24%). SNR alters were more likely than DR alters to be African American, uninsured, unemployed, homeless, sex workers, injection drug users, recently incarcerated, and have unmet service needs. Alters linked to care within 3 (69%), 4-6 (5%), and 7-12 months (8%), and 72% were retained at 6-12 months. The percent virally suppressed increased (27% vs. 41%) and the median viral load decreased (P = 0.003) between linkage and follow-up at 6-12 months. The alternative approaches presented were effective at locating marginalized HIV-positive persons who are OOC for linkage and retention. The SNR approach was most successful at identifying alters with serious social challenges and gaps in needed medical/ancillary services.

  12. Optical phase-modulated radio-over-fiber links with k-means algorithm for digital demodulation of 8PSK subcarrier multiplexed signals

    DEFF Research Database (Denmark)

    Guerrero Gonzalez, Neil; Zibar, Darko; Yu, Xianbin

    2010-01-01

    A k-means algorithm for phase recovery of three, 50 Mbaud, 8PSK subcarrier multiplexed signals at 5 GHz for optical phase-modulated radio-over-fiber is proposed and experimentally demonstrated after 40 km of single mode fiber transmission......A k-means algorithm for phase recovery of three, 50 Mbaud, 8PSK subcarrier multiplexed signals at 5 GHz for optical phase-modulated radio-over-fiber is proposed and experimentally demonstrated after 40 km of single mode fiber transmission...

  13. High-speed 1550 nm VCSEL data transmission link employing 25 Gbaud 4-PAM modulation and Hard Decision Forward Error Correction

    DEFF Research Database (Denmark)

    Rodes Lopez, Roberto; Mueller, M.; Li, Bomin

    2013-01-01

    Current short-range optical interconnects capacity is moving from 100 Gb/s to 400 Gb/s and beyond. Directly modulation of several laser sources is used to minimize bandwidth limitations of current optical and electrical components. Either this total capacity is provided by wavelengthdivision- mul...

  14. Interactive E-learning module in pharmacology: a pilot project at a rural medical college in India.

    Science.gov (United States)

    Gaikwad, Nitin; Tankhiwale, Suresh

    2014-01-01

    Many medical educators are experimenting with innovative ways of E-learning. E-learning provides opportunities to students for self-directed learning in addition to other advantages. In this study, we designed and evaluated an interactive E-learning module in pharmacology for effectiveness, acceptability and feasibility, with the aim of promoting active learning in this fact-filled subject. A quasi-experimental single-group pre-test/post-test study was conducted with fourth-semester students of the second professionals course (II MBBS), selected using non-probability convenience sampling method. An E-learning module in endocrine pharmacology was designed to comprise three units of interactive PowerPoint presentations. The pre-validated presentations were uploaded on the website according to a predefined schedule and the 42 registered students were encouraged to self-learning using these interactive presentations. Cognitive gain was assessed using an online pre- and post-test for each unit. Students' perceptions were recorded using an online feedback questionnaire on a 5-point Likert scale. Finally, focused group discussion was conducted to further explore students' views on E-learning activity. Significant attrition was observed during the E-learning activity. Of the 42 registered students, only 16 students completed the entire E-learning module. The summed average score of all three units (entire module) was increased significantly from 38.42 % (summed average pre-test score: 11.56/30 ± 2.90) to 66.46 % (summed average post-test score: 19.94/30 ± 6.13). The class-average normalized gain for the entire module was 0.4542 (45.42). The students accepted this E-learning activity well as they perceived it to be innovative, convenient, flexible and useful. The average rating was between 4 (agree) and 5 (strongly agree). The interactive E-learning module in pharmacology was moderately effective and well perceived by the students. The simple, cost-effective and

  15. Electrical and functional characterisation with single chips and module prototypes of the 1.2 Gb/s serial data link of the monolithic active pixel sensor for the upgrade of the ALICE Inner Tracking System

    CERN Document Server

    Bonora, Matthias; Aglieri Rinella, Gianluca; Hillemanns, Hartmut; Kim, Daehyeok; Kugathasan, Thanushan; Lattuca, Alessandra; Mazza, Giovanni; Sielewicz, Krzysztof Marek; Snoeys, Walter

    2017-01-01

    The upgrade of the ALICE Inner Tracking System uses a newly developed monolithic active pixel sensor (ALPIDE) which will populate seven tracking layers surrounding the interaction point. Chips communicate with the readout electronics using a 1.2 Gb/s data link and a 40 Mb/s bidirectional control link. Event data are transmitted to the readout electronics over microstrips on a Flexible Printed Circuit and a 6 m long twinaxial cable. This paper outlines the characterisation effort for assessing the Data Transmission Unit performance of single sensors and prototypes of the detector modules. It describes the different prototypes used, the test system and procedures, and results of laboratory and irradiation tests.

  16. High-speed three-dimensional shape measurement for dynamic scenes using bi-frequency tripolar pulse-width-modulation fringe projection

    Science.gov (United States)

    Zuo, Chao; Chen, Qian; Gu, Guohua; Feng, Shijie; Feng, Fangxiaoyu; Li, Rubin; Shen, Guochen

    2013-08-01

    This paper introduces a high-speed three-dimensional (3-D) shape measurement technique for dynamic scenes by using bi-frequency tripolar pulse-width-modulation (TPWM) fringe projection. Two wrapped phase maps with different wavelengths can be obtained simultaneously by our bi-frequency phase-shifting algorithm. Then the two phase maps are unwrapped using a simple look-up-table based number-theoretical approach. To guarantee the robustness of phase unwrapping as well as the high sinusoidality of projected patterns, TPWM technique is employed to generate ideal fringe patterns with slight defocus. We detailed our technique, including its principle, pattern design, and system setup. Several experiments on dynamic scenes were performed, verifying that our method can achieve a speed of 1250 frames per second for fast, dense, and accurate 3-D measurements.

  17. Module descriptor

    DEFF Research Database (Denmark)

    Vincenti, Gordon; Klausen, Bodil; Kjær Jensen, Jesper

    2016-01-01

    The Module Descriptor including a Teacher’s Guide explains and describes how to work innovatively and co-creatively with wicked problems and young people. The descriptor shows how interested educators and lecturers in Europe can copy the lessons of the Erasmus+ project HIP when teaching their own...

  18. Design and construction of the main linac module for the superconducting energy recovery linac project at Cornell

    Energy Technology Data Exchange (ETDEWEB)

    Eichhorn, R.; Bullock, B.; He, Y.; Hoffstaetter, G.; Liepe, M.; O' Connell, T.; Quigley, P.; Sabol, D.; Sears, J.; Smith, E.; Veshcherevich, V. [Cornell Laboratory for Accelerator-based Science and Education (CLASSE), Cornell University, 161 Synchrotron Drive, Ithaca, NY 14853 (United States)

    2014-01-29

    Cornell University has been designing and building superconducting accelerators for various applications for more than 50 years. Currently, an energy-recovery linac (ERL) based synchrotron-light facility is proposed making use of the existing CESR facility. As part of the phase 1 R and D program funded by the NSF, critical challenges in the design were addressed, one of them being a full linac cryo-module. It houses 6 superconducting cavities- operated at 1.8 K in continuous wave (CW) mode - with individual HOM absorbers and one magnet/ BPM section. Pushing the limits, a high quality factor of the cavities (2⋅10{sup 10}) and high beam currents (100 mA accelerated plus 100 mA decelerated) are targeted. We will present the design of the main linac cryo-module (MLC) being finalized recently, its cryogenic features and report on the status of the fabrication which started in late 2012.

  19. Space Vector Modulation for DC-Link Current Ripple Reduction in Back-To-Back Current Source Converters for Microgrid Applications

    DEFF Research Database (Denmark)

    Guo, Xiaoqiang; Xu, David; Guerrero, Josep M.

    2015-01-01

    Back-to-back converters have been typically used to interconnect the microgrids. For a back-to-back current source converter, the dc-link current ripple is one of the important parameters. A large ripple will cause the electromagnetic interference, undesirable high-frequency losses, and system...... instability. Conventionally, with a given switching frequency and rated voltage, the current ripple can be reduced by increasing the dc-link inductor, but it leads to bulky size, high cost and slow dynamic response. In order to solve this problem, this paper reveals that the current ripple can...

  20. Electroabsorption optical modulator

    Energy Technology Data Exchange (ETDEWEB)

    Skogen, Erik J.

    2017-11-21

    An electroabsorption modulator incorporates waveguiding regions along the length of the modulator that include quantum wells where at least two of the regions have quantum wells with different bandgaps. In one embodiment of the invention, the regions are arranged such that the quantum wells have bandgaps with decreasing bandgap energy along the length of the modulator from the modulator's input to its output. The bandgap energy of the quantum wells may be decreased in discrete steps or continuously. Advantageously, such an arrangement better distributes the optical absorption as well as the carrier density along the length of the modulator. Further advantageously, the modulator may handle increased optical power as compared with prior art modulators of similar dimensions, which allows for improved link gain when the optical modulator is used in an analog optical communication link.

  1. Class-Wide Access to a Commercial Step 1 Question Bank During Preclinical Organ-Based Modules: A Pilot Project.

    Science.gov (United States)

    Baños, James H; Pepin, Mark E; Van Wagoner, Nicholas

    2018-03-01

    The authors examined the usefulness of a commercially available Step 1 question bank as a formative academic support tool throughout organ-based modules in an integrated preclinical medical curriculum. The authors also determined the extent to which correlation between question bank utilization and academic metrics varied with Medical College Admission Test (MCAT) scores. In 2015, a cohort of 185 first-year medical students at University of Alabama School of Medicine were provided with 18-month full access to a commercially available Step 1 question bank of over 2,100 items throughout organ-based modules, although there were no requirements for use. Data on student use of the question bank were collected via an online administrative portal. Relationships between question bank utilization and academic outcomes including exams, module grades, and United States Medical Licensing Examination (USMLE) Step 1 were determined using multiple linear regression. MCAT scores and number of items attempted in the question bank significantly predicted all academic measures, with question bank utilization as the stronger predictor. The association between question bank utilization and academic outcome was stronger for individuals with lower MCAT scores. The findings elucidate a novel academic support mechanism that, for some programs, may help bridge the gap between holistic and mission-based admissions practices and a residency match process that places a premium on USMLE exam scores. Distributed formative use of USMLE Step 1 practice questions may be of value as an academic support tool that benefits all students, but particularly those entering with lower MCAT scores.

  2. Construction of a multisite DataLink using electronic health records for the identification, surveillance, prevention, and management of diabetes mellitus: the SUPREME-DM project.

    Science.gov (United States)

    Nichols, Gregory A; Desai, Jay; Elston Lafata, Jennifer; Lawrence, Jean M; O'Connor, Patrick J; Pathak, Ram D; Raebel, Marsha A; Reid, Robert J; Selby, Joseph V; Silverman, Barbara G; Steiner, John F; Stewart, W F; Vupputuri, Suma; Waitzfelder, Beth

    2012-01-01

    Electronic health record (EHR) data enhance opportunities for conducting surveillance of diabetes. The objective of this study was to identify the number of people with diabetes from a diabetes DataLink developed as part of the SUPREME-DM (SUrveillance, PREvention, and ManagEment of Diabetes Mellitus) project, a consortium of 11 integrated health systems that use comprehensive EHR data for research. We identified all members of 11 health care systems who had any enrollment from January 2005 through December 2009. For these members, we searched inpatient and outpatient diagnosis codes, laboratory test results, and pharmaceutical dispensings from January 2000 through December 2009 to create indicator variables that could potentially identify a person with diabetes. Using this information, we estimated the number of people with diabetes and among them, the number of incident cases, defined as indication of diabetes after at least 2 years of continuous health system enrollment. The 11 health systems contributed 15,765,529 unique members, of whom 1,085,947 (6.9%) met 1 or more study criteria for diabetes. The nonstandardized proportion meeting study criteria for diabetes ranged from 4.2% to 12.4% across sites. Most members with diabetes (88%) met multiple criteria. Of the members with diabetes, 428,349 (39.4%) were incident cases. The SUPREME-DM DataLink is a unique resource that provides an opportunity to conduct comparative effectiveness research, epidemiologic surveillance including longitudinal analyses, and population-based care management studies of people with diabetes. It also provides a useful data source for pragmatic clinical trials of prevention or treatment interventions.

  3. Construction of a Multisite DataLink Using Electronic Health Records for the Identification, Surveillance, Prevention, and Management of Diabetes Mellitus: The SUPREME-DM Project

    Science.gov (United States)

    Desai, Jay; Elston Lafata, Jennifer; Lawrence, Jean M.; O’Connor, Patrick J.; Pathak, Ram D.; Raebel, Marsha A.; Reid, Robert J.; Selby, Joseph V.; Silverman, Barbara G.; Steiner, John F.; Stewart, W.F.; Vupputuri, Suma; Waitzfelder, Beth

    2012-01-01

    Introduction Electronic health record (EHR) data enhance opportunities for conducting surveillance of diabetes. The objective of this study was to identify the number of people with diabetes from a diabetes DataLink developed as part of the SUPREME-DM (SUrveillance, PREvention, and ManagEment of Diabetes Mellitus) project, a consortium of 11 integrated health systems that use comprehensive EHR data for research. Methods We identified all members of 11 health care systems who had any enrollment from January 2005 through December 2009. For these members, we searched inpatient and outpatient diagnosis codes, laboratory test results, and pharmaceutical dispensings from January 2000 through December 2009 to create indicator variables that could potentially identify a person with diabetes. Using this information, we estimated the number of people with diabetes and among them, the number of incident cases, defined as indication of diabetes after at least 2 years of continuous health system enrollment. Results The 11 health systems contributed 15,765,529 unique members, of whom 1,085,947 (6.9%) met 1 or more study criteria for diabetes. The nonstandardized proportion meeting study criteria for diabetes ranged from 4.2% to 12.4% across sites. Most members with diabetes (88%) met multiple criteria. Of the members with diabetes, 428,349 (39.4%) were incident cases. Conclusion The SUPREME-DM DataLink is a unique resource that provides an opportunity to conduct comparative effectiveness research, epidemiologic surveillance including longitudinal analyses, and population-based care management studies of people with diabetes. It also provides a useful data source for pragmatic clinical trials of prevention or treatment interventions. PMID:22677160

  4. Selection of topologies for the PHOTONERGY{sup TM} project. Optimised design and control of inverter for photovoltaic systems: the AC-module

    Energy Technology Data Exchange (ETDEWEB)

    Baekhoej Kjaer, S.

    2002-06-01

    The PHOTONERGY{sup TM} project (also known as the former 'SolcelleInverter' project) is by this report carried into its third stage; the selection of a suitable topology for the AC-Module inverter. The selection of a suitable topology is based on State-Of-The-Art analysis a specifications and a comparison of four grid-tied inverters and nine dc/dc converters. This implies 23 possible combinations, from which nine is investigated with respect to efficiency in six working points, the number of components and to some extent also the rating of the components. The conclusion is that the target of a European efficiency of 93.7% is hard to achieve. But four of the examined, and two newly discovered, inverters are recommended for a further examination by means of estimations, calculations and simulations of: cost, complexity, robustness, efficiency and mass-production. The system-layout is also examined. The first layout implies that the PV-Module and the inverter is integrated into one unit and the second layout involves that the inverter is placed indoor. The layouts are compared with respect to cable-losses, enclosure demanding and lifetime. The conclusion is somehow ambiguous and a further investigation should be initiated in order to get a clear result. (au)

  5. Evaluation of the Urban Green Infrastructure using Landscape Modules, GIS and a Population Survey: Linking Environmental with Social Aspects in Studying and Managing Urban Forests

    OpenAIRE

    Gonzalez-Duque, Jose Antonio; Panagopoulos, Thomas

    2013-01-01

    Modern cities have to reconcile the needs of the citizens for green areas considering the evolutionary trends of the city, especially in terms of growth and the required transformation in modern times. The present study attempts to analyze and evaluate the amount and distribution of the existing urban green space and the requirements of those green areas by the public. The green infrastructure of the city of Faro was evaluated with three methods: landscape assessment using modules, spatial as...

  6. Ergodic channel capacity of spatial correlated multiple-input multiple-output free space optical links using multipulse pulse-position modulation

    Science.gov (United States)

    Wang, Huiqin; Wang, Xue; Cao, Minghua

    2017-02-01

    The spatial correlation extensively exists in the multiple-input multiple-output (MIMO) free space optical (FSO) communication systems due to the channel fading and the antenna space limitation. Wilkinson's method was utilized to investigate the impact of spatial correlation on the MIMO FSO communication system employing multipulse pulse-position modulation. Simulation results show that the existence of spatial correlation reduces the ergodic channel capacity, and the reception diversity is more competent to resist this kind of performance degradation.

  7. Analog lightwave links for detector front-ends at the LHC

    International Nuclear Information System (INIS)

    Baird, A.; Dowell, J.; Duthie, P.

    1995-01-01

    Lightwave links are being developed for volume application in the transfer of analog signals from the tracking detector front-ends to the readout electronics. The links are based on electro-optic intensity modulators which are mounted on detectors and connected by optical fibers to remotely located transceivers (lasers and photoreceivers). The modulators are 3--5 semiconductor reflective devices based on multi-quantum well structures. The transceivers will be integrated devices of a novel design. Modulator prototypes have been fabricated and tested. Neutron and γ-ray irradiation studies have been performed on modulators and fibers. The main results achieved so far are reported and key system issues are reviewed. This work is part of the CERN DRDC project RD23 project RD23

  8. Trace Fear Conditioning Differentially Modulates Intrinsic Excitability of Medial Prefrontal Cortex-Basolateral Complex of Amygdala Projection Neurons in Infralimbic and Prelimbic Cortices.

    Science.gov (United States)

    Song, Chenghui; Ehlers, Vanessa L; Moyer, James R

    2015-09-30

    Neuronal activity in medial prefrontal cortex (mPFC) is critical for the formation of trace fear memory, yet the cellular mechanisms underlying these memories remain unclear. One possibility involves the modulation of intrinsic excitability within mPFC neurons that project to the basolateral complex of amygdala (BLA). The current study used a combination of retrograde labeling and in vitro whole-cell patch-clamp recordings to examine the effect of trace fear conditioning on the intrinsic excitability of layer 5 mPFC-BLA projection neurons in adult rats. Trace fear conditioning significantly enhanced the intrinsic excitability of regular spiking infralimbic (IL) projection neurons, as evidenced by an increase in the number of action potentials after current injection. These changes were also associated with a reduction in spike threshold and an increase in h current. In contrast, trace fear conditioning reduced the excitability of regular spiking prelimbic (PL) projection neurons, through a learning-related decrease of input resistance. Interestingly, the amount of conditioned freezing was (1) positively correlated with excitability of IL-BLA projection neurons after conditioning and (2) negatively correlated with excitability of PL-BLA projection neurons after extinction. Trace fear conditioning also significantly enhanced the excitability of burst spiking PL-BLA projection neurons. In both regions, conditioning-induced plasticity was learning specific (observed in conditioned but not in pseudoconditioned rats), flexible (reversed by extinction), and transient (lasted extinction of trace fear conditioning. Significance statement: Frontal lobe-related function is vital for a variety of important behaviors, some of which decline during aging. This study involves a novel combination of electrophysiological recordings from fluorescently labeled mPFC-to-amygdala projection neurons in rats with acquisition and extinction of trace fear conditioning to determine how

  9. Chapter 4: Overview of the vegetation management treatment economic analysis module in the integrated landscape assessment project

    Science.gov (United States)

    Xiaoping Zhou; Miles A. Hemstrom

    2014-01-01

    Forest land provides various ecosystem services, including timber, biomass, and carbon sequestration. Estimating trends in these ecosystem services is essential for assessing potential outcomes of landscape management scenarios. However, the state-and transition models used in the Integrated Landscape Assessment Project for simulating landscape changes over time do not...

  10. The Implementation and Evaluation of a Project-Oriented Problem-Based Learning Module in a First Year Engineering Programme

    Science.gov (United States)

    McLoone, Seamus C.; Lawlor, Bob J.; Meehan, Andrew R.

    2016-01-01

    This paper describes how a circuits-based project-oriented problem-based learning educational model was integrated into the first year of a Bachelor of Engineering in Electronic Engineering programme at Maynooth University, Ireland. While many variations of problem based learning exist, the presented model is closely aligned with the model used in…

  11. Apollo-Soyuz test project. Operations handbook command/service/docking modules (CSM 119/DM 1): Operational procedures reference issue

    Science.gov (United States)

    1974-01-01

    Operational and configuration checks for the Apollo-Soyuz Test Project are presented. The checks include: backup crew prelaunch, prime crew prelaunch, boost and insertion, G and C reference data, G and N reference modes, rendezvous, navigation, Apollo-Soyuz operations, abort procedures, and emergency procedures.

  12. Stuttering interneurons generate fast and robust inhibition onto projection neurons with low capacity of short term modulation in mouse lateral amygdala.

    Directory of Open Access Journals (Sweden)

    Chen Song

    Full Text Available The stuttering interneurons (STi represent one minor subset of interneuron population and exhibit characteristic stuttering firing upon depolarization current injection. While it has been long held that the GABAergic inhibitory transmission largely varies with the subtype identity of presynaptic interneurons, whether such a rule also applies to STi is largely unknown. Here, by paired recording of interneuron and their neighboring projection neuron in lateral amygdala, we found that relative to the fast spiking and late spiking interneurons, the STi-evoked unitary postsynaptic currents onto the projection neurons had markedly larger amplitude, shorter onset latency and faster rising and decay kinetics. The quantal content and the number of vesicles in the readily releasable pool were also larger in synapses made by STi versus other interneurons. Moreover, the short-term plasticity, as reflected by the paired pulse depression and depolarization-induced suppression of inhibition, was the least prominent in the output synapses of STi. Thus, the fast and robust inhibition together with its low capacity of short term modulation may suggest an important role for STi in preventing the overexcitation of the projection neurons and thus gating the information traffic in amygdala.

  13. Three-dimensional shape profiling by out-of-focus projection of colored pulse width modulation fringe patterns.

    Science.gov (United States)

    Silva, Adriana; Flores, Jorge L; Muñoz, Antonio; Ayubi, Gastón A; Ferrari, José A

    2017-06-20

    Three-dimensional (3D) shape profiling by sinusoidal phase-shifting methods is affected by the non-linearity of the projector. To overcome this problem, the defocusing technique has become an important alternative to generate sinusoidal fringe patterns. The precision of this method depends on the binary pattern used and on the defocusing applied. To improve the defocusing technique, we propose the implementation of a color-based binary fringe patterns. The proposed technique involves the generation of colored pulse width modulation (PWM) fringe patterns, which are generated with different frequencies at the carrier signal. From an adequate selection of these frequencies, the colored PWM fringe patterns will lead to amplitude harmonics lower than the conventional PWM fringe patterns. Hence, the defocusing can decrease, and the 3D shape profiling can be more accurate. Numerical simulations and experimental results are presented as validation.

  14. Beam test results of STS prototype modules for the future accelerator experiments FAIR/CBM and NICA/MPD projects

    Science.gov (United States)

    Kharlamov, Petr; Dementev, Dmitrii; Shitenkov, Mikhail

    2017-10-01

    High-energy heavy-ion collision experiments provide the unique possibility to create and investigate extreme states of strongly-interacted matter and address the fundamental aspects of QCD. The experimental investigation the QCD phase diagram would be a major breakthrough in our understanding of the properties of nuclear matter. The reconstruction of the charged particles created in the nuclear collisions, including the determination of their momenta, is the central detection task in high-energy heavy-ion experiments. It is taken up by the Silicon Tracking System in CBM@FAIR and by Inner Tracker in MPD@NICA currently under development. These experiments requires very fast and radiation hard detectors, a novel data read-out and analysis concept including free streaming front-end electronics. Thermal and beam tests of prototype detector modules for these tracking systems showed the stability of sensors and readout electronics operation.

  15. Beam test results of STS prototype modules for the future accelerator experiments FAIR/CBM and NICA/MPD projects

    Directory of Open Access Journals (Sweden)

    Kharlamov Petr

    2017-01-01

    Full Text Available High-energy heavy-ion collision experiments provide the unique possibility to create and investigate extreme states of strongly-interacted matter and address the fundamental aspects of QCD. The experimental investigation the QCD phase diagram would be a major breakthrough in our understanding of the properties of nuclear matter. The reconstruction of the charged particles created in the nuclear collisions, including the determination of their momenta, is the central detection task in high-energy heavy-ion experiments. It is taken up by the Silicon Tracking System in CBM@FAIR and by Inner Tracker in MPD@NICA currently under development. These experiments requires very fast and radiation hard detectors, a novel data read-out and analysis concept including free streaming front-end electronics. Thermal and beam tests of prototype detector modules for these tracking systems showed the stability of sensors and readout electronics operation.

  16. An overview of the US work to complete the design of Blanket Shield Modules 7,12 and 13 for the ITER project

    International Nuclear Information System (INIS)

    Ulrickson, M.; Coats, R.; Garde, J.

    2007-01-01

    Part of the US contribution to the ITER project is Blanket Shield Modules (BSM) number 7, 12 and 13 comprising about 20% of the ITER First Wall. These modules are all in the upper half of the vacuum vessel. Starting from outlines of each style of module, general design rules contained in the ITER Design Description Document (DDD), design memos, and CATIA interface drawings, the US Team has worked to fill in the details of the internal water cooling passages, slits to control eddy currents, and methods for efficient and reliable manufacturing of the BSM. Our analysis begins with nuclear heating assessment of complex 3D structures containing water, copper, and steel carried out by the University of Wisconsin using a version of Monte Carlo N-Particle Transport Code (MCNP) that connects directly to CATIA to get the geometry. Computational Fluid Dynamics (CFD) analysis of the coolant flow distribution and pressure drop in a shield module provides the basis for thermal transfer from the BSM to the coolant. The size and position of coolant passages are adjusted to optimize the heat transfer and eliminate hot spots. ITER specified major disruption (MD) and downward vertical disruption (VDE) events are used to calculate the currents induced in the BSM. In this modeling it is necessary to include the vacuum vessel and other BSM near the modules of interest. In order to benchmark the OPERA Electromagnetic Code against the one used for the DDD analysis, we calculated eddy currents and forces on all 18 BSM in a simplified model that matched analysis by Japan. The eddy current forces are used to determine the torque and net force on the BSM. These forces are compared to the load capacity of the mounts and adjustments made to eddy current control slits as needed. Dynamic analysis of the eddy current induced stresses on the BSM and mounts are performed using the ABAQUS code. Static thermal and pressure stresses are calculated using the temperature distributions from CFD analysis

  17. Using linked data to evaluate severity and outcome of injury by type of object struck (first object struck only) for motor vehicle crashes in Connecticut : Crash Outcome Data Evaluation System (CODES) linked data demonstration project

    Science.gov (United States)

    1999-09-01

    A deterministic algorithm was developed which allowed data from Department of Transportation motor vehicle crash records, state mortality registry records, and hospital admission and emergency department records to be linked for analysis of the types...

  18. Phosphorylation of actin-binding protein (ABP-280; filamin) by tyrosine kinase p56lck modulates actin filament cross-linking.

    Science.gov (United States)

    Pal Sharma, C; Goldmann, Wolfgang H

    2004-01-01

    Actin-binding protein (ABP-280; filamin) is a phosphoprotein present in the periphery of the cytoplasm where it can cross-link actin filaments, associate with lipid membranes, and bind to membrane surface receptors. Given its function and localization in the cell, we decided to investigate the possibility of whether it serves as substrate for p56lck, a lymphocyte-specific member of the src family of protein tyrosine kinases associated with cell surface glycoproteins. The interaction of p56lck with membrane glycoproteins is important for cell development and functional activation. Here, we show that purified p56lck interacts and catalyzes in vitro kinase reactions. Tyrosine phosphorylation by p56lck is restricted to a single peptide of labeled ABP-280 shown by protease digest. The addition of phorbol ester to cells results in the inhibition of phosphorylation of ABP-280 by p56lck. These results show a decrease in phosphorylation suggesting conformationally induced regulation. Dynamic light scattering confirmed increased actin filament cross-linking due to phosphorylation of ABP-280 by p56lck.

  19. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Notes Podcasts E-Newsletters Public Education Projects National Drug & Alcohol Facts Week NIDA TV PEERx Drugs & Health Blog ... Award for Addiction Science USA Science & Engineering Festival Drug & Alcohol Chat Day HBO Addiction Project Learn the Link ...

  20. A study of 60 Gigahertz intersatellite link applications

    Science.gov (United States)

    Anzic, G.; Connolly, D. J.; Haugland, E. J.; Kosmahl, H. G.; Chitwood, J. S.

    Applications of intersatellite links operating at 60 GHz are reviewed. Likely scenarios, ranging from transmission of moderate and high data rates over long distances to low data rates over short distances are examined. A limited parametric tradeoff is performed with system variables such as radiofrequency power, receiver noise temperature, link distance, data rate, and antenna size. Present status is discussed and projections are given for both electron tube and solid state transmitter technologies. Monolithic transmit and receive module technology, already under development at 20 to 30 GHz, is reviewed and its extension to 60 GHz, and possible applicability is discussed.

  1. A study of 60 GHz intersatellite link applications

    Science.gov (United States)

    Anzic, G.; Connolly, D. J.; Haugland, E. J.; Kosmahl, H. G.; Chitwood, J. S.

    Applications of intersatellite links operating at 60 GHz are reviewed. Likely scenarios, ranging from transmission of moderate and high data rates over long distances to low data rates over short distances are examined. A limited parametric tradeoff is performed with system variables such as radiofrequency power, receiver noise temperature, link distance, data rate, and antenna size. Present status is discussed and projections are given for both electron tube and solid state transmitter technologies. Monolithic transmit and receive module technology, already under development at 20 to 30 GHz, is reviewed and its extension to 60 GHz, and possible applicability is discussed.

  2. A study of 60 Gigahertz intersatellite link applications

    Science.gov (United States)

    Anzic, G.; Connolly, D. J.; Haugland, E. J.; Kosmahl, H. G.; Chitwood, J. S.

    1983-01-01

    Applications of intersatellite links operating at 60 GHz are reviewed. Likely scenarios, ranging from transmission of moderate and high data rates over long distances to low data rates over short distances are examined. A limited parametric tradeoff is performed with system variables such as radiofrequency power, receiver noise temperature, link distance, data rate, and antenna size. Present status is discussed and projections are given for both electron tube and solid state transmitter technologies. Monolithic transmit and receive module technology, already under development at 20 to 30 GHz, is reviewed and its extension to 60 GHz, and possible applicability is discussed.

  3. A study of 60 GHz intersatellite link applications

    Science.gov (United States)

    Anzic, G.; Connolly, D. J.; Haugland, E. J.; Kosmahl, H. G.; Chitwood, J. S.

    1983-01-01

    Applications of intersatellite links operating at 60 GHz are reviewed. Likely scenarios, ranging from transmission of moderate and high data rates over long distances to low data rates over short distances are examined. A limited parametric tradeoff is performed with system variables such as radiofrequency power, receiver noise temperature, link distance, data rate, and antenna size. Present status is discussed and projections are given for both electron tube and solid state transmitter technologies. Monolithic transmit and receive module technology, already under development at 20 to 30 GHz, is reviewed and its extension to 60 GHz, and possible applicability is discussed.

  4. Project COLD.

    Science.gov (United States)

    Kazanjian, Wendy C.

    1982-01-01

    Describes Project COLD (Climate, Ocean, Land, Discovery) a scientific study of the Polar Regions, a collection of 35 modules used within the framework of existing subjects: oceanography, biology, geology, meterology, geography, social science. Includes a partial list of topics and one activity (geodesic dome) from a module. (Author/SK)

  5. The DAF-16 FOXO transcription factor regulates natc-1 to modulate stress resistance in Caenorhabditis elegans, linking insulin/IGF-1 signaling to protein N-terminal acetylation.

    Directory of Open Access Journals (Sweden)

    Kurt Warnhoff

    2014-10-01

    Full Text Available The insulin/IGF-1 signaling pathway plays a critical role in stress resistance and longevity, but the mechanisms are not fully characterized. To identify genes that mediate stress resistance, we screened for C. elegans mutants that can tolerate high levels of dietary zinc. We identified natc-1, which encodes an evolutionarily conserved subunit of the N-terminal acetyltransferase C (NAT complex. N-terminal acetylation is a widespread modification of eukaryotic proteins; however, relatively little is known about the biological functions of NATs. We demonstrated that loss-of-function mutations in natc-1 cause resistance to a broad-spectrum of physiologic stressors, including multiple metals, heat, and oxidation. The C. elegans FOXO transcription factor DAF-16 is a critical target of the insulin/IGF-1 signaling pathway that mediates stress resistance, and DAF-16 is predicted to directly bind the natc-1 promoter. To characterize the regulation of natc-1 by DAF-16 and the function of natc-1 in insulin/IGF-1 signaling, we analyzed molecular and genetic interactions with key components of the insulin/IGF-1 pathway. natc-1 mRNA levels were repressed by DAF-16 activity, indicating natc-1 is a physiological target of DAF-16. Genetic studies suggested that natc-1 functions downstream of daf-16 to mediate stress resistance and dauer formation. Based on these findings, we hypothesize that natc-1 is directly regulated by the DAF-16 transcription factor, and natc-1 is a physiologically significant effector of the insulin/IGF-1 signaling pathway that mediates stress resistance and dauer formation. These studies identify a novel biological function for natc-1 as a modulator of stress resistance and dauer formation and define a functionally significant downstream effector of the insulin/IGF-1 signaling pathway. Protein N-terminal acetylation mediated by the NatC complex may play an evolutionarily conserved role in regulating stress resistance.

  6. The DAF-16 FOXO transcription factor regulates natc-1 to modulate stress resistance in Caenorhabditis elegans, linking insulin/IGF-1 signaling to protein N-terminal acetylation.

    Science.gov (United States)

    Warnhoff, Kurt; Murphy, John T; Kumar, Sandeep; Schneider, Daniel L; Peterson, Michelle; Hsu, Simon; Guthrie, James; Robertson, J David; Kornfeld, Kerry

    2014-10-01

    The insulin/IGF-1 signaling pathway plays a critical role in stress resistance and longevity, but the mechanisms are not fully characterized. To identify genes that mediate stress resistance, we screened for C. elegans mutants that can tolerate high levels of dietary zinc. We identified natc-1, which encodes an evolutionarily conserved subunit of the N-terminal acetyltransferase C (NAT) complex. N-terminal acetylation is a widespread modification of eukaryotic proteins; however, relatively little is known about the biological functions of NATs. We demonstrated that loss-of-function mutations in natc-1 cause resistance to a broad-spectrum of physiologic stressors, including multiple metals, heat, and oxidation. The C. elegans FOXO transcription factor DAF-16 is a critical target of the insulin/IGF-1 signaling pathway that mediates stress resistance, and DAF-16 is predicted to directly bind the natc-1 promoter. To characterize the regulation of natc-1 by DAF-16 and the function of natc-1 in insulin/IGF-1 signaling, we analyzed molecular and genetic interactions with key components of the insulin/IGF-1 pathway. natc-1 mRNA levels were repressed by DAF-16 activity, indicating natc-1 is a physiological target of DAF-16. Genetic studies suggested that natc-1 functions downstream of daf-16 to mediate stress resistance and dauer formation. Based on these findings, we hypothesize that natc-1 is directly regulated by the DAF-16 transcription factor, and natc-1 is a physiologically significant effector of the insulin/IGF-1 signaling pathway that mediates stress resistance and dauer formation. These studies identify a novel biological function for natc-1 as a modulator of stress resistance and dauer formation and define a functionally significant downstream effector of the insulin/IGF-1 signaling pathway. Protein N-terminal acetylation mediated by the NatC complex may play an evolutionarily conserved role in regulating stress resistance.

  7. Real-time microscopic 3D shape measurement based on optimized pulse-width-modulation binary fringe projection

    Science.gov (United States)

    Hu, Yan; Chen, Qian; Feng, Shijie; Tao, Tianyang; Li, Hui; Zuo, Chao

    2017-07-01

    In recent years, tremendous progress has been made in 3D measurement techniques, contributing to the realization of faster and more accurate 3D measurement. As a representative of these techniques, fringe projection profilometry (FPP) has become a commonly used method for real-time 3D measurement, such as real-time quality control and online inspection. To date, most related research has been concerned with macroscopic 3D measurement, but microscopic 3D measurement, especially real-time microscopic 3D measurement, is rarely reported. However, microscopic 3D measurement plays an important role in 3D metrology and is indispensable in some applications in measuring micro scale objects like the accurate metrology of MEMS components of the final devices to ensure their proper performance. In this paper, we proposed a method which effectively combines optimized binary structured patterns with a number-theoretical phase unwrapping algorithm to realize real-time microscopic 3D measurement. A slight defocusing of our optimized binary patterns can considerably alleviate the measurement error based on four-step phase-shifting FPP, providing the binary patterns with a comparable performance to ideal sinusoidal patterns. The static measurement accuracy can reach 8 μm, and the experimental results of a vibrating earphone diaphragm reveal that our system can successfully realize real-time 3D measurement of 120 frames per second (FPS) with a measurement range of 8~\\text{mm}× 6~\\text{mm} in lateral and 8 mm in depth.

  8. A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction

    Directory of Open Access Journals (Sweden)

    Samman Ayman

    2008-08-01

    Full Text Available Abstract Feline immunodeficiency virus (FIV targets helper T cells by attachment of the envelope glycoprotein (Env to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry. As the CXCR4 binding site is not exposed until CD134-binding has occurred then the virus is protected from neutralising antibodies targeting the CXCR4-binding site on Env. Prototypic FIV vaccines based on the FL4 strain of FIV contain a cell culture-adapted strain of FIV Petaluma, a CD134-independent strain of FIV that interacts directly with CXCR4. In addition to a characteristic increase in charge in the V3 loop homologue of FIVFL4, we identified two mutations in potential sites for N-linked glycosylation in the region of FIV Env analogous to the V1–V2 region of HIV and SIV Env, T271I and N342Y. When these mutations were introduced into the primary GL8 and CPG41 strains of FIV, the T271I mutation was found to alter the nature of the virus-CD134 interaction; primary viruses carrying the T271I mutation no longer required determinants in cysteine-rich domain (CRD 2 of CD134 for viral entry. The T271I mutation did not confer CD134-independent infection upon GL8 or CPG41, nor did it increase the affinity of the CXCR4 interaction, suggesting that the principal effect was targeted at reducing the complexity of the Env-CD134 interaction.

  9. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... for young people, parents and teachers, and the media with links to our latest research findings and news updates. Read on to Learn the Link between ... to this site at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . ... Social Media Send the message to young people and to ...

  10. ASI-Volcanic Risk System (SRV): a pilot project to develop EO data processing modules and products for volcanic activity monitoring, first results.

    Science.gov (United States)

    Silvestri, M.; Musacchio, M.; Buongiorno, M. F.; Dini, L.

    2009-04-01

    The Project called Sistema Rischio Vulcanico (SRV) is funded by the Italian Space Agency (ASI) in the frame of the National Space Plan 2003-2005 under the Earth Observations section for natural risks management. The SRV Project is coordinated by the Istituto Nazionale di Geofisica e Vulcanologia (INGV) which is responsible at national level for the volcanic monitoring. The project philosophy is to implement, by incremental versions, specific modules which allow to process, store and visualize through Web GIS tools geophysical parameters suitable for volcanic risk management. The ASI-SRV is devoted to the development of an integrated system based on Earth Observation (EO) data to respond to specific needs of the Italian Civil Protection Department (DPC) and improve the monitoring of Italian active volcanoes during all the risk phases (Pre Crisis, Crisis and Post Crisis). The ASI-SRV system provides support to risk managers during the different volcanic activity phases and its results are addressed to the Italian Civil Protection Department (DPC). SRV provides the capability to manage the import many different EO data into the system, it maintains a repository where the acquired data have to be stored and generates selected volcanic products. The processing modules for EO Optical sensors data are based on procedures jointly developed by INGV and University of Modena. This procedures allow to estimate a number of parameters such as: surface thermal proprieties, gas, aerosol and ash emissions and to characterize the volcanic products in terms of composition and geometry. For the analysis of the surface thermal characteristics, the available algorithms allow to extract information during the prevention phase and during the Warning and Crisis phase. In the prevention phase the thermal analysis is directed to the identification of temperature variation on volcanic structure which may indicate a change in the volcanic activity state. At the moment the only sensor that

  11. ASTP crewmen in Docking Module trainer during training session at JSC

    Science.gov (United States)

    1975-01-01

    An interior view of the Docking Module trainer in bldg 35 during Apollo Soyuz Test Project (ASTP) joint crew training at JSC. Astronaut Thomas P. Stafford, commander of the American ASTP prime crew, is on the right. The other crewman is Cosmonaut Aleksey A. Leonov, commander of the Soviet ASTP prime crew. The training session simulated activities on the second day in Earth orbit. The Docking Module is designed to link the Apollo and Soyuz spacecraft.

  12. Empowering pharmacoinformatics by linked life science data.

    Science.gov (United States)

    Goldmann, Daria; Zdrazil, Barbara; Digles, Daniela; Ecker, Gerhard F

    2017-03-01

    With the public availability of large data sources such as ChEMBLdb and the Open PHACTS Discovery Platform, retrieval of data sets for certain protein targets of interest with consistent assay conditions is no longer a time consuming process. Especially the use of workflow engines such as KNIME or Pipeline Pilot allows complex queries and enables to simultaneously search for several targets. Data can then directly be used as input to various ligand- and structure-based studies. In this contribution, using in-house projects on P-gp inhibition, transporter selectivity, and TRPV1 modulation we outline how the incorporation of linked life science data in the daily execution of projects allowed to expand our approaches from conventional Hansch analysis to complex, integrated multilayer models.

  13. Experimental studies and modelling of cation interactions with solid materials: application to the MIMICC project. (Multidimensional Instrumented Module for Investigations on chemistry-transport Coupled Codes)

    International Nuclear Information System (INIS)

    Hardin, Emmanuelle

    1999-01-01

    The study of cation interactions with solid materials is useful in order to define the chemistry interaction component of the MIMICC project (Multidimensional Instrumented Module for Investigations on chemistry-transport Coupled Codes). This project will validate the chemistry-transport coupled codes. Database have to be supplied on the cesium or ytterbium interactions with solid materials in suspension. The solid materials are: a strong cation exchange resin, a natural sand which presents small impurities, and a zirconium phosphate. The cation exchange resin is useful to check that the surface complexation theory can be applied on a pure cation exchanger. The sand is a natural material, and its isotherms will be interpreted using pure oxide-cation system data, such as pure silica-cation data. Then the study on the zirconium phosphate salt is interesting because of the increasing complexity in the processes (dissolution, sorption and co-precipitation). These data will enable to approach natural systems, constituted by several complex solids which can interfere on each other. These data can also be used for chemistry-transport coupled codes. Potentiometric titration, sorption isotherms, sorption kinetics, cation surface saturation curves are made, in order to obtain the different parameters relevant to the cation sorption at the solid surface, for each solid-electrolyte-cation system. The influence of different parameters such as ionic strength, pH, and electrolyte is estimated. All the experimental curves are fitted with FITEQL code based on the surface complexation theory using the constant capacitance model, in order to give a mechanistic interpretation of the ion retention phenomenon at the solid surface. The speciation curves of all systems are plotted, using the FITEQL code too. Systems with an increasing complexity are studied: dissolution, sorption and coprecipitation coexist in the cation-salt systems. Then the data obtained on each single solid, considered

  14. FASTBUS Snoop Diagnostic Module

    International Nuclear Information System (INIS)

    Walz, H.V.; Downing, R.

    1980-11-01

    Development of the FASTBUS Snoop Module, undertaken as part of the prototype program for the new interlaboratory data bus standard, is described. The Snoop Module resides on a FASTBUS crate segment and provides diagnostic monitoring and testing capability. Communication with a remote host computer is handled independent of FASTBUS through a serial link. The module consists of a high-speed ECL front-end to monitor and single-step FASTBUS cycles, a master-slave interface, and a control microprocessor with serial communication ports. Design details and performance specifications of the prototype module are reported. 9 figures, 1 table

  15. Analysis of second order harmonic distortion due to transmitter non-linearity and chromatic and modal dispersion of optical OFDM SSB modulated signals in SMF-MMF fiber links

    Science.gov (United States)

    Patel, Dhananjay; Singh, Vinay Kumar; Dalal, U. D.

    2017-01-01

    Single mode fibers (SMF) are typically used in Wide Area Networks (WAN), Metropolitan Area Networks (MAN) and also find applications in Radio over Fiber (RoF) architectures supporting data transmission in Fiber to the Home (FTTH), Remote Antenna Units (RAUs), in-building networks etc. Multi-mode fibers (MMFs) with low cost, ease of installation and low maintenance are predominantly (85-90%) deployed in-building networks providing data access in local area networks (LANs). The transmission of millimeter wave signals through the SMF in WAN and MAN, along with the reuse of MMF in-building networks will not levy fiber reinstallation cost. The transmission of the millimeter waves experiences signal impairments due to the transmitter non-linearity and modal dispersion of the MMF. The MMF exhibiting large modal dispersion limits the bandwidth-length product of the fiber. The second and higher-order harmonics present in the optical signal fall within the system bandwidth. This causes degradation in the received signal and an unwanted radiation of power at the RAU. The power of these harmonics is proportional to the non-linearity of the transmitter and the modal dispersion of the MMF and should be maintained below the standard values as per the international norms. In this paper, a mathematical model is developed for Second-order Harmonic Distortion (HD2) generated due to non-linearity of the transmitter and chromatic-modal dispersion of the SMF-MMF optic link. This is also verified using a software simulation. The model consists of a Mach Zehnder Modulator (MZM) that generates two m-QAM OFDM Single Sideband (SSB) signals based on phase shift of the hybrid coupler (90° and 120°). Our results show that the SSB signal with 120° hybrid coupler has suppresses the higher-order harmonics and makes the system more robust against the HD2 in the SMF-MMF optic link.

  16. Operative Links

    DEFF Research Database (Denmark)

    Wistoft, Karen; Højlund, Holger

    2012-01-01

    educational goals, learning content, or value clarification. Health pedagogy is often a matter of retrospective rationalization rather than the starting point of planning. Health and risk behaviour approaches override health educational approaches. Conclusions: Operational links between health education......, health professionalism, and management strategies pose the foremost challenge. Operational links indicates cooperative levels that facilitate a creative and innovative effort across traditional professional boundaries. It is proposed that such links are supported by network structures, shared semantics...

  17. Librarians as Advocates of Social Media for Researchers: A Social Media Project Initiated by Linköping University Library, Sweden

    Science.gov (United States)

    Persson, Sassa; Svenningsson, Maria

    2016-01-01

    Librarians at Linköping University help researchers keep abreast of developments in their fields and to increase the visibility of their work. Strategic, professional use of social media ought to be an essential part of a researcher's communication strategy. This article investigates the level of awareness of the professional use of social media…

  18. Projecting water yield and ecosystem productivity across the United States by linking an ecohydrological model to WRF dynamically downscaled climate data

    Science.gov (United States)

    Shanlei Sun; Ge Sun; Erika Cohen Mack; Steve McNulty; Peter V. Caldwell; Kai Duan; Yang Zhang

    2016-01-01

    Quantifying the potential impacts of climatechange on water yield and ecosystem productivity is essential to developing sound watershed restoration plans, andecosystem adaptation and mitigation strategies. This study links an ecohydrological model (Water Supply and StressIndex, WaSSI) with WRF (Weather Research and Forecasting Model) using dynamically downscaled...

  19. Narcissism and the Strategic Pursuit of Short-Term Mating : Pervasive Links across 11 World Regions of the International Sexuality Description Project-2

    NARCIS (Netherlands)

    Schmitt, David; Vanwesenbeeck, W.M.A.

    2017-01-01

    Previous studies have documented links between sub-clinical narcissism and the active pursuit of short-term mating strategies (e.g., unrestricted sociosexuality, marital infidelity, mate poaching). Nearly all of these investigations have relied solely on samples from Western cultures. In the current

  20. Microwaves photonic links components and circuits

    CERN Document Server

    Rumelhard, Christian; Billabert, Anne-Laure

    2013-01-01

    This book presents the electrical models for the different elements of a photonic microwave link like lasers, external modulators, optical fibers, photodiodes and phototransistors. The future trends of these components are also introduced: lasers to VCSEL, external modulators to electro-absorption modulators, glass optical fibers to plastic optical fibers, photodiodes to UTC photodiodes or phototransistors. It also describes an original methodology to evaluate the performance of a microwave photonic link, based on the developed elcetrical models, that can be easily incorporated in

  1. The Strip Module

    DEFF Research Database (Denmark)

    Pedersen, Tommy

    1996-01-01

    When the behaviour of a ship in waves is to be predicted it is convenient to have a tool which includes different approaches to the problem.The aim of this project is to develop such a tool named the strip theory module. The strip theory module will consist of submodules dependent on the I...

  2. Narcissism and the Strategic Pursuit of Short-Term Mating: Universal Links across 11 World Regions of the International Sexuality Description Project-2

    OpenAIRE

    Schmitt, David P.; Alcalay, Lidia; Allik, Jüri; Alves, I. C. B.; Anderson, Craig A.; Angelini, A. L.; Asendorpf, Jens B.; Austers, Ivars; Balaguer, Isabel; Baptista, Américo; Bender, Sóley S.; Bennett, Kevin; Bianchi, Gabriel; Bianchi, Behrooz; Bleske-Rechek, April

    2017-01-01

    Previous studies have documented links between sub-clinical narcissism and the active pursuit of short-term mating strategies (e.g., unrestricted sociosexuality, marital infidelity, mate poaching). Nearly all of these investigations have relied solely on samples from Western cultures. In the current study, responses from a cross-cultural survey of 30,470 people across 53 nations spanning 11 world regions (North America, Central/South America, Northern Europe, Western Europe, Eastern Europe, S...

  3. Narcissism and the strategic pursuit of short-term mating : universal links across 11 world regions of the International Sexuality Description Project-2.

    OpenAIRE

    Schmitt, David; Alcalay, Lidia; Allik, Jüri; Alves, I.C.B.; Anderson, Craig; Angelini, A.L.; Asendorpf, Jens; Austers, Ivars; Balaguer, Isabel; Baptista, Américo; Bender, Sóley; Bennett, Kevin; Bianchi, Gabriel; Birashk, Behrooz; Bleske, April

    2017-01-01

    Previous studies have documented links between sub-clinical narcissism and the active pursuit of short-term mating strategies (e.g., unrestricted sociosexuality, marital infidelity, mate poaching). Nearly all of these investigations have relied solely on samples from Western cultures. In the current study, responses from a cross-cultural survey of 30,470 people across 53 nations spanning 11 world regions (North America, Central/South America, Northern Europe, Western Europe, Eastern Europe, S...

  4. A statistical rain attenuation prediction model with application to the advanced communication technology satellite project. 3: A stochastic rain fade control algorithm for satellite link power via non linear Markow filtering theory

    Science.gov (United States)

    Manning, Robert M.

    1991-01-01

    The dynamic and composite nature of propagation impairments that are incurred on Earth-space communications links at frequencies in and above 30/20 GHz Ka band, i.e., rain attenuation, cloud and/or clear air scintillation, etc., combined with the need to counter such degradations after the small link margins have been exceeded, necessitate the use of dynamic statistical identification and prediction processing of the fading signal in order to optimally estimate and predict the levels of each of the deleterious attenuation components. Such requirements are being met in NASA's Advanced Communications Technology Satellite (ACTS) Project by the implementation of optimal processing schemes derived through the use of the Rain Attenuation Prediction Model and nonlinear Markov filtering theory.

  5. Tertiary Students' Intention to e-Collaborate for Group Projects: Exploring the Missing Link from an Extended Theory of Planned Behaviour Model

    Science.gov (United States)

    Cheng, Eddie W. L.; Chu, Samuel K. W.; Ma, Carol S. M.

    2016-01-01

    With the emergence of web technologies, students can conduct their group projects via virtual platforms, which enable online collaboration. However, students' lack of intention to use web technologies for conducting group work has recently been highlighted. Based on the theory of planned behaviour (TPB), this paper developed and examined an…

  6. On the ultimate capacity of SI-POF links and the use of OFDM: recent results from the POF-ALL project

    NARCIS (Netherlands)

    Gaudino, R.; Bosco, G.; Bluschke, A.; Hofmann, O.; Kiss, N.; Matthews, M.; Rietzsch, P.; Randel, S.; Lee, S.C.J.; Breyer, F.

    2007-01-01

    The use of standard 1-mm SI-POF has been so far mainly limited to distances below 100 meters and low bitrates, of the order of 100 Mbps. The EU project POF-ALL is currently investigating on how to extend these limits in terms of both increased reach and/or higher bit-rates. Among the different

  7. The socio-political effects of forced migrations linked to major hydraulic projects in China. The example of the Three Gorges dam - CERI Studies No. 103

    International Nuclear Information System (INIS)

    Padovani, Florence

    2004-04-01

    The study of the population movements caused by the major Chinese hydraulic projects reveals the true extent of the change which has come about in relations between the State and society in China. The construction of the Three Gorges dam - which led to considerable controversy both within China and beyond - is a prime case in point. As well as its social consequences, this infrastructure project has ramifications in the political, economic and legal domains, notably because of the forced migrations which it has entailed. The manner in which this question has been managed - both by central government, which planned the project, and by the provincial governments, which had to manage time constraints and financial and human resources at first hand - illustrates the extent to which the country has moved away from the authoritarian approach which had currency under the rule of Chairman Mao. The study of the project provides insights into the manner in which the authorities on the ground actually applied the directives received from the Centre, and into the difficulty encountered by the rulers in Beijing in ensuring that their centralised vision of the new China holds sway. The way in which the sensitive issue of forced migrations has been managed highlights what is at stake in the disputes between the various players, i.e. officials in the many ministries concerned, local and provincial authorities, displaced populations and host populations. The specific modes of justification employed by each group provide pointers towards an understanding of the complexity of China's new 'civil society'. (author)

  8. TeSeR – Technology for Self-Removal – First results of an H2020 Project to develop a Post-Mission-Disposal Module

    DEFF Research Database (Denmark)

    Voigt, p.; Vogt, C.; Schubert, R.

    2017-01-01

    The goal of TeSeR (Technology for Self-Removal) is to take the first step towards the development of a scalable, flexible, cost-efficient, but highly reliable Post-Mission-Disposal (PMD) module. This module is to be attached to the spacecraft (S/C) on ground and it shall ensure the PMD of the S/C...

  9. Weighted network modules

    International Nuclear Information System (INIS)

    Farkas, Illes; Abel, Daniel; Palla, Gergely; Vicsek, Tamas

    2007-01-01

    The inclusion of link weights into the analysis of network properties allows a deeper insight into the (often overlapping) modular structure of real-world webs. We introduce a clustering algorithm clique percolation method with weights (CPMw) for weighted networks based on the concept of percolating k-cliques with high enough intensity. The algorithm allows overlaps between the modules. First, we give detailed analytical and numerical results about the critical point of weighted k-clique percolation on (weighted) Erdos-Renyi graphs. Then, for a scientist collaboration web and a stock correlation graph we compute three-link weight correlations and with the CPMw the weighted modules. After reshuffling link weights in both networks and computing the same quantities for the randomized control graphs as well, we show that groups of three or more strong links prefer to cluster together in both original graphs

  10. An European pupil project linked to the scientific aims of the experiment AQUARIUS-XENOPUS on the taxi Soyuz flight Andromede to ISS.

    Science.gov (United States)

    Dournon, Christian; Membre, Herve; Brohm, Pierre-Eric; Coince, Aurore; Cornu, Nathalie; Dreyer, Laura; Florentin, Jonathan; Jeanneau, Lydie; Henniquin, Camille; Houbre, Marie; Guerard, Marine; Lecomte, Nathalie; Maxant, Lorie; Schluraff, Marion; Venandet, Anne-Sophie; Jusyte, Aiste; Simmet, Dana; Bocking, Dominique; Flaig, Dorothee; Santak, Leo; Bolek, Steffen; Goppel, Verena; Rossignon, Jean-Paul; Trossat, Marie-Alice; Raux, Martine; Forster, Susanne; Staudenmaier, Gerd; Boser, Sybille; Horn, Eberhard

    2002-07-01

    The German-French biological experiment AQUARIUS-XENOPUS which flew on the Soyuz flight Andromede to the International Space Station ISS (launched October 21, 2001 in Baikonour/Kazakhstan) was extended by an outreach project. Pupils of class 10 to 12 from Ulm/D and Nancy-Tomblaine/F studied swimming behavior of Xenopus tadpoles on ground. They were instructed to perform all experimental steps following the protocol of similar video recordings on ISS. After the flight, they evaluated the kinetics of swimming of both ground controls and space animals. The pupil project included theoretical components to introduce them to the field of gravitational biology. One feature of the project was the exchange of ideas between pupils by meetings which took place in Ulm (June 2001), Nancy (February 2002) and Paris (May 2002). We consider our approach as a successful way to include young people in space experiments on a cheap cost level and to bring ideas of gravitational biology into the curricula of European schools.

  11. Front end data link processor

    International Nuclear Information System (INIS)

    Wallace, J.J.

    1988-01-01

    It is possible to expand the data acquisition capabilities of an existing process computer to include other dedicated computer based systems, provided each system has at least minimal data link capabilities. The following paper discusses the addition of three computer based acquisition systems to a Honeywell 4500C (also designated the 45000) running the SEER system. Only one data link port was required to support the link. Each of the three specialized systems implemented data link protocols used by their suppliers in previous projects: none of the three were compatible with Honeywell's protocol. Part one of the following provides a generic overview of the project and would be relevent to the operator of any process system interested in expansion. Part two provides specific details of this project and may serve to provide performance benchmarks to those who wish to consider a similar project

  12. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... NIDA Donating to NIDA Frequently Asked Questions Contact Us Sharing Tools and Badges Other Resources Strategic Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn ...

  13. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to parents, teachers, and the media about the link between drug misuse and HIV. Post on Facebook or Twitter ; add photos to your Flickr , ...

  14. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ... HIV/AIDS and the discovery of promising treatment interventions for breaking the harmful links between them, we ...

  15. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to parents, teachers, and the media about the link between drug ...

  16. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse Commonly Abused Drugs Charts Emerging ... Badges Other Resources Strategic Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - ...

  17. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... site. Please link these banners back to this site at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to ...

  18. Utah Text Retrieval Project

    Energy Technology Data Exchange (ETDEWEB)

    Hollaar, L A

    1983-10-01

    The Utah Text Retrieval project seeks well-engineered solutions to the implementation of large, inexpensive, rapid text information retrieval systems. The project has three major components. Perhaps the best known is the work on the specialized processors, particularly search engines, necessary to achieve the desired performance and cost. The other two concern the user interface to the system and the system's internal structure. The work on user interface development is not only concentrating on the syntax and semantics of the query language, but also on the overall environment the system presents to the user. Environmental enhancements include convenient ways to browse through retrieved documents, access to other information retrieval systems through gateways supporting a common command interface, and interfaces to word processing systems. The system's internal structure is based on a high-level data communications protocol linking the user interface, index processor, search processor, and other system modules. This allows them to be easily distributed in a multi- or specialized-processor configuration. It also allows new modules, such as a knowledge-based query reformulator, to be added. 15 references.

  19. Scandinavian links

    DEFF Research Database (Denmark)

    Matthiessen, Christian Wichmann; Knowles, Richard D.

    2014-01-01

    are impressive mega structures spanning international waterways. These waterways between the Baltic Sea and the North Sea have played major roles in history. The length of each of the crossings are around 20 km. The fixed links closes gaps between the Scandinavian and European motorway and rail networks...

  20. Images of Stakeholder Groups Based on Their Environmental Sustainability Linked CSR Projects: A Meta-Analytic Review of Korean Sport Literature

    Directory of Open Access Journals (Sweden)

    Hyun-Duck Kim

    2017-09-01

    Full Text Available Achieving sustainability in sports events requires effective management, political leadership, and ensuring that all stakeholders adhere to a sustainable philosophy. In order to stage a mega-event, tremendous infrastructure and construction are required with significant consumption of private and public resources. Multiple stakeholder groups are recognized as key entities responsible for an efficient trigger of a mega-event. The aim of this study is to conduct a systematic review of Korean sport literature with regard to CSR practices (ES-linked of different stakeholder groups and examine through a meta-analytic methodology their impact on the “images” of these groups. The CMA program was utilized as the main analysis tool to calculate the effect sizes from the selected empirical studies. The results indicated that CSR performance of governmental organizations had the highest effect size level on their own image (brand identity as perceived by visitors and participants. Among the stakeholder groups, effect size levels of their CSR performances were followed by those of corporate sponsors and professional teams. It was found that stakeholder groups are pressured to maintain a balance between financial performance, consumer well-being, and brand identity to bring in external investment.

  1. Sci-Thurs PM: Delivery-08: Investigation of the source of RF noise from a modulator for an MR-linac project.

    Science.gov (United States)

    Lamey, M; Burke, B; Rathee, S; Fallone, B G; Carlone, M

    2008-07-01

    The next significant step in the advancement of IGRT is the integration of an MRI with a linac. The MRI-linac will provide images with exquisite soft tissue contrast in real-time during treatment. A possible problem associated with the proposed integration is the RF noise generated by the linac. This noise could interfere with the received signals of the MRI producing deleterious effects in the image quality. The work herein is concerned with understanding the processes involved in the RF noise production and the magnitude and frequency of this RF noise in the modulator of a linac. A software programming environment, MultiSIM, was used to model the electronic components of a modulator. Several Current and Voltage waveforms from the modulator were measured with an oscilloscope and compared with the corresponding results from the modulator model for validation. Finally, RF noise generated by the modulator was measured using field probes, which permits the frequency components of the measured and simulated modulator waveforms to be compared with the measured RF noise. The modeled PFN charging current and voltage, and klystron current show good agreement with measurements, with the exception of the tail of the klystron voltage signal. Once the model has been validated in both the time and frequency domains, future work will entail predicting pulse shape changes when, and if, modifications to the modulator are made. Specifically, modifications will be made which shift and/or reduce the RF noise in the frequency range of interest for a 0.2T MRI. © 2008 American Association of Physicists in Medicine.

  2. Narcissism and the Strategic Pursuit of Short-Term Mating: Universal Links across 11 World Regions of the International Sexuality Description Project-2

    Directory of Open Access Journals (Sweden)

    David P. Schmitt et al.

    2017-05-01

    Full Text Available Previous studies have documented links between sub-clinical narcissism and the active pursuit of short-term mating strategies (e.g., unrestricted sociosexuality, marital infidelity, mate poaching. Nearly all of these investigations have relied solely on samples from Western cultures. In the current study, responses from a cross-cultural survey of 30,470 people across 53 nations spanning 11 world regions (North America, Central/South America, Northern Europe, Western Europe, Eastern Europe, Southern Europe, Middle East, Africa, Oceania, Southeast Asia, and East Asia were used to evaluate whether narcissism (as measured by the Narcissistic Personality Inventory; NPI was universally associated with short-term mating. Results revealed narcissism scores (including two broad factors and seven traditional facets as measured by the NPI were functionally equivalent across cultures, reliably associating with key sexual outcomes (e.g., more active pursuit of short-term mating, intimate partner violence, and sexual aggression and sex-related personality traits (e.g., higher extraversion and openness to experience. Whereas some features of personality (e.g., subjective well-being were universally associated with socially adaptive facets of Narcissism (e.g., self-sufficiency, most indicators of short-term mating (e.g., unrestricted sociosexuality and marital infidelity were universally associated with the socially maladaptive facets of narcissism (e.g., exploitativeness. Discussion addresses limitations of these cross-culturally universal findings and presents suggestions for future research into revealing the precise psychological features of narcissism that facilitate the strategic pursuit of short-term mating.

  3. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... News NIDA Notes Podcasts E-Newsletters Public Education Projects Contact the Press Office Meetings & Events Media Guide ... Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn the ...

  4. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the News NIDA Notes Podcasts E-Newsletters Public Education Projects Contact the Press Office Meetings & Events Media ... Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn ...

  5. Linking GHG Emission Trading Systems and Markets

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    Several different types of links are possible between different GHG-mitigation systems. These include: Linking two or more emission trading schemes so that emissions trading can occur both within and between different schemes ('direct links'); and Linking emission trading systems to registries/mechanisms and systems that generate offsets from project based mechanisms or from direct purchases/transfers of AAUs ('indirect links').

  6. Projecting regional climate and cropland changes using a linked biogeophysical-socioeconomic modeling framework: 1. Model description and an equilibrium application over West Africa

    Science.gov (United States)

    Wang, Guiling; Ahmed, Kazi Farzan; You, Liangzhi; Yu, Miao; Pal, Jeremy; Ji, Zhenming

    2017-03-01

    Agricultural land use alters regional climate through modifying the surface mass, energy, and momentum fluxes; climate influences agricultural land use through their impact on crop yields. These interactions are not well understood and have not been adequately considered in climate projections. This study tackles the critical linkages within the coupled natural-human system of West Africa in a changing climate based on an equilibrium application of a modeling framework that asynchronously couples models of regional climate, crop yield, multimarket agricultural economics, and cropland expansion. Using this regional modeling framework driven with two global climate models, we assess the contributions of land use change (LUC) and greenhouse gas (GHGs) concentration changes to regional climate changes and assess the contribution of climate change and socioeconomic factors to agricultural land use changes. For future cropland expansion in West Africa, our results suggest that socioeconomic development would be the dominant driver in the east (where current cropland coverage is already high) and climate changes would be the primary driver in the west (where future yield drop is severe). For future climate, it is found that agricultural expansion would cause a dry signal in the west and a wet signal in the east downwind, with an east-west contrast similar to the GHG-induced changes. Over a substantial portion of West Africa, the strength of the LUC-induced climate signals is comparable to the GHG-induced changes. Uncertainties originating from the driving global models are small; human decision making related to land use and international trade is a major source of uncertainty.

  7. Linked Ocean Data

    Science.gov (United States)

    Leadbetter, Adam; Arko, Robert; Chandler, Cynthia; Shepherd, Adam

    2014-05-01

    "Linked Data" is a term used in Computer Science to encapsulate a methodology for publishing data and metadata in a structured format so that links may be created and exploited between objects. Berners-Lee (2006) outlines the following four design principles of a Linked Data system: Use Uniform Resource Identifiers (URIs) as names for things. Use HyperText Transfer Protocol (HTTP) URIs so that people can look up those names. When someone looks up a URI, provide useful information, using the standards (Resource Description Framework [RDF] and the RDF query language [SPARQL]). Include links to other URIs so that they can discover more things. In 2010, Berners-Lee revisited his original design plan for Linked Data to encourage data owners along a path to "good Linked Data". This revision involved the creation of a five star rating system for Linked Data outlined below. One star: Available on the web (in any format). Two stars: Available as machine-readable structured data (e.g. An Excel spreadsheet instead of an image scan of a table). Three stars: As two stars plus the use of a non-proprietary format (e.g. Comma Separated Values instead of Excel). Four stars: As three stars plus the use of open standards from the World Wide Web Commission (W3C) (i.e. RDF and SPARQL) to identify things, so that people can point to your data and metadata. Five stars: All the above plus link your data to other people's data to provide context Here we present work building on the SeaDataNet common vocabularies served by the NERC Vocabulary Server, connecting projects such as the Rolling Deck to Repository (R2R) and the Biological and Chemical Oceanography Data Management Office (BCO-DMO) and other vocabularies such as the Marine Metadata Interoperability Ontology Register and Repository and the NASA Global Change Master Directory to create a Linked Ocean Data cloud. Publishing the vocabularies and metadata in standard RDF XML and exposing SPARQL endpoints renders them five-star Linked

  8. BioProject

    Data.gov (United States)

    U.S. Department of Health & Human Services — The BioProject database provides an organizational framework to access information about research projects with links to data that have been or will be deposited...

  9. The Levi-Civita Tensor and Identities in Vector Analysis. Vector Field Identities. Modules and Monographs in Undergraduate Mathematics and Its Applications Project. UMAP Unit 427.

    Science.gov (United States)

    Yiu, Chang-li; Wilde, Carroll O.

    Vector analysis is viewed to play a key role in many branches of engineering and the physical sciences. This unit is geared towards deriving identities and establishing "machinery" to make derivations a routine task. It is noted that the module is not an applications unit, but has as its primary objective the goal of providing science,…

  10. Nuclear Deterrence. Applications of Elementary Probability to International Relations. Modules and Monographs in Undergraduate Mathematics and Its Applications Project. UMAP Unit 327.

    Science.gov (United States)

    Smith, Harvey A.

    This module is designed to apply mathematical models to nuclear deterrent problems, and to aid users in developing enlightened skepticism about the use of linear models in stability analyses and long-term predictions. An attempt is made at avoiding overwhelming complexities through concentration on land-based missile forces. It is noted that after…

  11. The RHIC real time data link system

    International Nuclear Information System (INIS)

    Hartmann, H.

    1997-01-01

    The RHIC Real Time Data Link (RTDL) System distributes to all locations around the RHIC ring machine parameters of general interest to accelerator systems and users. The system, along with supporting host interface, is centrally located. The RTDL System is comprised of two module types: the Encoder Module (V105) and the Input Module (V106). There is only one V105 module, but many (up to 128) Input Modules. Multiple buffered outputs are provided for use locally or for retransmission to other RHIC equipment locations. Machine parameters are generated from the V115 Waveform Generator Module (WFG) or from machine hardware and coupled directly through a fiber optic serial link to one of the V106 input channels

  12. Operative links

    DEFF Research Database (Denmark)

    Wistoft, Karen

    2010-01-01

    and have been the object of great expectations concerning the ability to incorporate health concerns into every welfare area through health promotion strategies. The paper draws on results and analyses of a collective research project funded by the Danish National Research Council and carried out...

  13. ASI-Sistema Rischio Vulcanico SRV: a pilot project to develop EO data processing modules and products for volcanic activity monitoring based on Italian Civil Protection Department requirements and needs

    Science.gov (United States)

    Buongiorno, Maria Fabrizia; Musacchio, Massimo; Silvestri, Malvina; Spinetti, Claudia; Corradini, Stefano; Lombardo, Valerio; Merucci, Luca; Sansosti, Eugenio; Pugnagli, Sergio; Teggi, Sergio; Pace, Gaetano; Fermi, Marco; Zoffoli, Simona

    2007-10-01

    The Project called Sistema Rischio Vulcanico (SRV) is funded by the Italian Space Agency (ASI) in the frame of the National Space Plan 2003-2005 under the Earth Observations section for natural risks management. The SRV Project is coordinated by the Istituto Nazionale di Geofisica e Vulcanologia (INGV) which is responsible at national level for the volcanic monitoring. The objective of the project is to develop a pre-operative system based on EO data and ground measurements integration to support the volcanic risk monitoring of the Italian Civil Protection Department which requirements and need are well integrated in the GMES Emergency Core Services program. The project philosophy is to implement, by incremental versions, specific modules which allow to process, store and visualize through Web GIS tools EO derived parameters considering three activity phases: 1) knowledge and prevention; 2) crisis; 3) post crisis. In order to combine effectively the EO data and the ground networks measurements the system will implement a multi-parametric analysis tool, which represents and unique tool to analyze contemporaneously a large data set of data in "near real time". The SRV project will be tested his operational capabilities on three Italian Volcanoes: Etna,Vesuvio and Campi Flegrei.

  14. CAMAC based computer--computer communications via microprocessor data links

    International Nuclear Information System (INIS)

    Potter, J.M.; Machen, D.R.; Naivar, F.J.; Elkins, E.P.; Simmonds, D.D.

    1976-01-01

    Communications between the central control computer and remote, satellite data acquisition/control stations at The Clinton P. Anderson Meson Physics Facility (LAMPF) is presently accomplished through the use of CAMAC based Data Link Modules. With the advent of the microprocessor, a new philosophy for digital data communications has evolved. Data Link modules containing microprocessor controllers provide link management and communication network protocol through algorithms executed in the Data Link microprocessor

  15. Multiplication modules over non-commutative rings

    International Nuclear Information System (INIS)

    Tuganbaev, A A

    2003-01-01

    It is proved that each submodule of a multiplication module over a regular ring is a multiplicative module. If A is a ring with commutative multiplication of right ideals, then each projective right ideal is a multiplicative module, and a finitely generated A-module M is a multiplicative module if and only if all its localizations with respect to maximal right ideals of A are cyclic modules over the corresponding localizations of A. In addition, several known results on multiplication modules over commutative rings are extended to modules over not necessarily commutative rings

  16. IX Disposition Project - project management plan

    International Nuclear Information System (INIS)

    Choi, I.G.

    1994-01-01

    This report presents plans for resolving saving and disposal concerns for ion exchange modules, cartridge filters and columns. This plan also documents the project baselines for schedules, cost, and technical information

  17. Freeway project to link east and west

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    <正> Construction work on aWorld Bank-financed sectionof a 1,400-kilometre freewaywill break ground in CentralChina’s Henan Province. Contracts for the earthwork of the Zhengzhou-Luoyang section of the freeway,backed by 120 million in

  18. 100 Gb/s single VCSEL data transmission link

    DEFF Research Database (Denmark)

    Rodes Lopez, Roberto; Estaran Tolosa, Jose Manuel; Li, Bomin

    2012-01-01

    100 Gb/s optical fiber transmission link with a single 1.5 um VCSEL has been experimentally demonstrated using 4-level pulse amplitude modulation.......100 Gb/s optical fiber transmission link with a single 1.5 um VCSEL has been experimentally demonstrated using 4-level pulse amplitude modulation....

  19. Versatile Link PLUS transceiver development

    International Nuclear Information System (INIS)

    Soós, C.; Détraz, S.; Olanterä, L.; Sigaud, C.; Troska, J.; Vasey, F.; Zeiler, M.

    2017-01-01

    The Versatile Link PLUS project targets the phase II upgrades of the ATLAS and CMS experiments. It will develop a radiation resistant optical link, operating at up to 10 Gb/s in the upstream and up to 5 Gb/s in the downstream directions with a smaller footprint and higher channel count than its predecessor. A low-profile package is being developed that allows volume production at reduced costs, but which nevertheless can be configured to suit the individual channel count needs of different detectors. This paper describes the development strategies and summarizes the status of the feasibility demonstration phase of the project.

  20. Photovoltaic concentrator module improvements study

    Energy Technology Data Exchange (ETDEWEB)

    Levy, S.L.; Kerschen, K.A. (Black and Veatch, Kansas City, MO (United States)); Hutchison, G. (Solar Kinetics, Inc., Dallas, TX (United States)); Nowlan, M.J. (Spire Corp., Bedford, MA (United States))

    1991-08-01

    This report presents results of a project to design and fabricate an improved photovoltaic concentrator module. Using previous work as a baseline, this study conducted analyses and testing to select major module components and design features. The lens parquet and concentrator solar cell were selected from the highest performing, available components. A single 185X point-focus module was fabricated by the project team and tested at Sandia. Major module characteristics include a 6 by 4 compression-molded acrylic lens parquet (0.737 m{sup 2} area), twenty-four 0.2 ohms-cm, FZ, p-Si solar cells (1.56 cm{sup 2} area) soldered to ceramic substrates and copper heat spreaders, and an aluminized steel housing with corrugated bottom. This project marked the first attempt to use prismatic covers on solar cells in a high-concentration, point-focus application. Cells with 15 percent metallization were obtained, but problems with the fabrication and placement of prismatic covers on these cells lead to the decision not to use covers in the prototype module. Cell assembly fabrication, module fabrication, and module optical design activities are presented here. Test results are also presented for bare cells, cell assemblies, and module. At operating conditions of 981 watts/m{sup 2} DNI and an estimated cell temperature of 65{degrees}C, the module demonstrated an efficiency of 13.9 percent prior to stressed environmental exposure. 12 refs., 56 figs., 7 tabs.

  1. Samba for solar modules. Brazil decides reimbursement strategy and starts pilot projects; Samba fuer Solarmodule. Brasilien macht den Weg fuer die Einspeisung von Solarstrom frei und startet Pilotprojekte

    Energy Technology Data Exchange (ETDEWEB)

    Rosell, Alejandro Diego

    2012-06-15

    Better late than never: After long years of discussion, Brazil recently decided on a reimbursement strategy. Further, pilot projects with a total of 24 MW are in te planning stage. While some expect a major invitation for tender, local experts warn of rough times ahead.

  2. Automatic modulation classification principles, algorithms and applications

    CERN Document Server

    Zhu, Zhechen

    2014-01-01

    Automatic Modulation Classification (AMC) has been a key technology in many military, security, and civilian telecommunication applications for decades. In military and security applications, modulation often serves as another level of encryption; in modern civilian applications, multiple modulation types can be employed by a signal transmitter to control the data rate and link reliability. This book offers comprehensive documentation of AMC models, algorithms and implementations for successful modulation recognition. It provides an invaluable theoretical and numerical comparison of AMC algo

  3. Investigating Quantum Modulation States

    Science.gov (United States)

    2016-03-01

    Coherent state quantum data encryption is highly interoperable with current classical optical infrastructure in both fiber and free space optical networks...hub’s field of regard has a transmit/receive module that are endpoints of the Lyot filter stage tree within the hub’s backend electro-optics control... mobile airborne and space-borne networking. Just like any laser communication technology, QC links are affected by several sources of distortions

  4. A organização da atividade de gerenciamento de projetos: os nexos com competências e estrutura Project management activity organization: links between competences and structure

    Directory of Open Access Journals (Sweden)

    Roque Rabechini Junior

    2011-01-01

    Full Text Available O objetivo deste trabalho é estudar os vínculos existentes entre as práticas de gerenciamento de projetos vis-à-vis a adequação da estrutura e das competências organizacionais. A metodologia de estudo de caso foi escolhida para auxiliar na apresentação deste trabalho na forma de resultados de uma investigação empírica. A pesquisa foi realizada em uma empresa da cadeia produtiva do setor automobilístico. Os resultados apontaram os fatores determinantes da estrutura, dos quais se destacam: a falta de memória técnica, o desenvolvimento gerencial e o custo da estrutura. Além disso, foi constatado um cenário de baixas competências nos âmbitos do indivíduo, das equipes e da organização.This study aims to understand the links between project management practices and organizational structure and competences. The case study methodology was chosen in order to present an empirical investigation. The research was conducted in a company in the automotive sector. The results show the structure determinants, among which are: lack of memory technology, management development, and cost structure. Furthermore, a scenario of low competences was found in the individual, team , and organizational dimensions.

  5. Accident and safety analyses for the HTR-modul. Partial project 1: Computer codes for system behaviour calculation. Final report. Pt. 1

    International Nuclear Information System (INIS)

    Lohnert, G.; Becker, D.; Dilcher, L.; Doerner, G.; Feltes, W.; Gysler, G.; Haque, H.; Kindt, T.; Kohtz, N.; Lange, L.; Ragoss, H.

    1993-08-01

    The project encompasses the following project tasks and problems: (1) Studies relating to complete failure of the main heat transfer system; (2) Pebble flow; (3) Development of computer codes for detailed calculation of hypothetical accidents; (a) the THERMIX/RZKRIT temperature buildup code (covering a.o. a variation to include exothermal heat sources); (b) the REACT/THERMIX corrosion code (variation taking into account extremely severe air ingress into the primary loop); (c) the GRECO corrosion code (variation for treating extremely severe water ingress into the primary loop); (d) the KIND transients code (for treating extremely fast transients during reactivity incidents. (4) Limiting devices for safety-relevant quantities. (5) Analyses relating to hypothetical accidents. (a) hypothetical air ingress; (b) effects on the fuel particles induced by fast transients. The problems of the various tasks are defined in detail and the main results obtained are explained. The contributions reporting the various project tasks and activities have been prepared for separate retrieval from the database. (orig./HP) [de

  6. Accident and safety analyses for the HTR-modul. Partial project 1: Computer codes for system behaviour calculation. Final report. Pt. 2

    International Nuclear Information System (INIS)

    Lohnert, G.; Becker, D.; Dilcher, L.; Doerner, G.; Feltes, W.; Gysler, G.; Haque, H.; Kindt, T.; Kohtz, N.; Lange, L.; Ragoss, H.

    1993-08-01

    The project encompasses the following project tasks and problems: (1) Studies relating to complete failure of the main heat transfer system; (2) Pebble flow; (3) Development of computer codes for detailed calculation of hypothetical accidents; (a) the THERMIX/RZKRIT temperature buildup code (covering a.o. a variation to include exothermal heat sources); (b) the REACT/THERMIX corrosion code (variation taking into account extremely severe air ingress into the primary loop); (c) the GRECO corrosion code (variation for treating extremely severe water ingress into the primary loop); (d) the KIND transients code (for treating extremely fast transients during reactivity incidents. (4) Limiting devices for safety-relevant quantities. (5) Analyses relating to hypothetical accidents. (a) hypothetical air ingress; (b) effects on the fuel particles induced by fast transients. The problems of the various tasks are defined in detail and the main results obtained are explained. The contributions reporting the various project tasks and activities have been prepared for separate retrieval from the database. (orig./HP) [de

  7. Sex-linked dominant

    Science.gov (United States)

    Inheritance - sex-linked dominant; Genetics - sex-linked dominant; X-linked dominant; Y-linked dominant ... can be either an autosomal chromosome or a sex chromosome. It also depends on whether the trait ...

  8. SU-E-T-174: Evaluation of the Optimal Intensity Modulated Radiation Therapy Plans Done On the Maximum and Average Intensity Projection CTs

    Energy Technology Data Exchange (ETDEWEB)

    Jurkovic, I [University of Texas Health Science Center at San Antonio, San Antonio, TX (United States); Stathakis, S; Li, Y; Patel, A; Vincent, J; Papanikolaou, N; Mavroidis, P [Cancer Therapy and Research Center University of Texas Health Sciences Center at San Antonio, San Antonio, TX (United States)

    2014-06-01

    Purpose: To determine the difference in coverage between plans done on average intensity projection and maximum intensity projection CT data sets for lung patients and to establish correlations between different factors influencing the coverage. Methods: For six lung cancer patients, 10 phases of equal duration through the respiratory cycle, the maximum and average intensity projections (MIP and AIP) from their 4DCT datasets were obtained. MIP and AIP datasets had three GTVs delineated (GTVaip — delineated on AIP, GTVmip — delineated on MIP and GTVfus — delineated on each of the 10 phases and summed up). From the each GTV, planning target volumes (PTV) were then created by adding additional margins. For each of the PTVs an IMRT plan was developed on the AIP dataset. The plans were then copied to the MIP data set and were recalculated. Results: The effective depths in AIP cases were significantly smaller than in MIP (p < 0.001). The Pearson correlation coefficient of r = 0.839 indicates strong degree of positive linear relationship between the average percentage difference in effective depths and average PTV coverage on the MIP data set. The V2 0 Gy of involved lung depends on the PTV coverage. The relationship between PTVaip mean CT number difference and PTVaip coverage on MIP data set gives r = 0.830. When the plans are produced on MIP and copied to AIP, r equals −0.756. Conclusion: The correlation between the AIP and MIP data sets indicates that the selection of the data set for developing the treatment plan affects the final outcome (cases with high average percentage difference in effective depths between AIP and MIP should be calculated on AIP). The percentage of the lung volume receiving higher dose depends on how well PTV is covered, regardless of on which set plan is done.

  9. Photovoltaic module mounting system

    Science.gov (United States)

    Miros, Robert H. J. [Fairfax, CA; Mittan, Margaret Birmingham [Oakland, CA; Seery, Martin N [San Rafael, CA; Holland, Rodney H [Novato, CA

    2012-04-17

    A solar array mounting system having unique installation, load distribution, and grounding features, and which is adaptable for mounting solar panels having no external frame. The solar array mounting system includes flexible, pedestal-style feet and structural links connected in a grid formation on the mounting surface. The photovoltaic modules are secured in place via the use of attachment clamps that grip the edge of the typically glass substrate. The panel mounting clamps are then held in place by tilt brackets and/or mid-link brackets that provide fixation for the clamps and align the solar panels at a tilt to the horizontal mounting surface. The tilt brackets are held in place atop the flexible feet and connected link members thus creating a complete mounting structure.

  10. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... and what to do to counter these trends. Online Resources NIDA for Teens Web site : This Web ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ...

  11. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... women can pass HIV to their babies during pregnancy, delivery, and breastfeeding. HIV destroys a certain kind ... at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 ...

  12. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ... following television networks, organizations, educational institutions, magazines, newspapers, companies, events, and radio stations for helping to raise ...

  13. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ... gov/1kSfBiz ​ Mention your friends, colleagues, or other organizations in your tweets to spread the word even ...

  14. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ... available for your use to share on your social media accounts. About the Campaign Overview The Learn ...

  15. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ... the Party" "Text Message" NIDA Home Site Map Accessibility Privacy FOIA(NIH) Working at NIDA FAQs Contact ...

  16. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... HIV to their babies during pregnancy, delivery, and breastfeeding. HIV destroys a certain kind of white blood ... at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 ...

  17. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to ... available for your use to share on your social media accounts. About the Campaign Overview The Learn the ...

  18. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and to parents, teachers, and the media ...

  19. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... and what to do to counter these trends. Online Resources NIDA for Teens Web site : This Web ... at: http://www.drugabuse.gov/news-events/public-education-projects/learn-link-drugs-hiv . 120x90 460x80 486x60 ...

  20. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Adolescent Brain Comorbidity College-Age & Young Adults Criminal Justice Drugged Driving Drug Testing Drugs and the Brain ... projects/learn-link-drugs-hiv . 120x90 460x80 486x60 Social Media Send the message to young people and ...

  1. Multi-Functional Fibre-Optic Microwave Links

    DEFF Research Database (Denmark)

    Gliese, Ulrik Bo

    1998-01-01

    The multi-functionality of microwave links based on remote heterodyne detection of signals from a dual-frequency laser transmitter is discussed and experimentally demonstrated in this paper. Typically, direct detection in conjunction with optical intensity modulation is used to implement fibre......-optic microwave links. The resulting links are inherently transparent and mainly used for signal transmission. As opposed to direct detection links, remote heterodyne detection links can directly perform functionalities such as modulation, frequency conversion, and transparent signal recovery in addition...

  2. SLAC modulator system improvements and reliability results

    International Nuclear Information System (INIS)

    Donaldson, A.R.

    1998-06-01

    In 1995, an improvement project was completed on the 244 klystron modulators in the linear accelerator. The modulator system has been previously described. This article offers project details and their resulting effect on modulator and component reliability. Prior to the project, the authors had collected four operating cycles (1991 through 1995) of MTTF data. In this discussion, the '91 data will be excluded since the modulators operated at 60 Hz. The five periods following the '91 run were reviewed due to the common repetition rate at 120 Hz

  3. Negative response of photosynthesis to natural and projected high seawater temperatures estimated by pulse amplitude modulation fluorometry in a temperate coral.

    Science.gov (United States)

    Caroselli, Erik; Falini, Giuseppe; Goffredo, Stefano; Dubinsky, Zvy; Levy, Oren

    2015-01-01

    Balanophyllia europaea is a shallow water solitary zooxanthellate coral, endemic to the Mediterranean Sea. Extensive field studies across a latitudinal temperature gradient highlight detrimental effects of rising temperatures on its growth, demography, and skeletal characteristics, suggesting that depression of photosynthesis at high temperatures might cause these negative effects. Here we test this hypothesis by analyzing, by means of pulse amplitude modulation fluorometry, the photosynthetic efficiency of B. europaea specimens exposed in aquaria to the annual range of temperatures experienced in the field (13, 18, and 28°C), and two extreme temperatures expected for 2100 as a consequence of global warming (29 and 32°C). The indicators of photosynthetic performance analyzed (maximum and effective quantum yield) showed that maximum efficiency was reached at 20.0-21.6°C, slightly higher than the annual mean temperature in the field (18°C). Photosynthetic efficiency decreased from 20.0 to 13°C and even more strongly from 21.6 to 32°C. An unusual form of bleaching was observed, with a maximum zooxanthellae density at 18°C that strongly decreased from 18 to 32°C. Chlorophyll a concentration per zooxanthellae cell showed an opposite trend as it was minimal at 18°C and increased from 18 to 32°C. Since the areal chlorophyll concentration is the product of the zooxanthellae density and its cellular content, these trends resulted in a homogeneous chlorophyll concentration per coral surface across temperature treatments. This confirms that B. europaea photosynthesis is progressively depressed at temperatures >21.6°C, supporting previous hypotheses raised by the studies on growth and demography of this species. This study also confirms the threats posed to this species by the ongoing seawater warming.

  4. Negative response of photosynthesis to natural and projected high seawater temperatures estimated by pulse amplitude modulation fluorometry in a temperate coral

    Directory of Open Access Journals (Sweden)

    Erik eCaroselli

    2015-11-01

    Full Text Available Balanophyllia europaea is a shallow water solitary zooxanthellate coral, endemic to the Mediterranean Sea. Extensive field studies across a latitudinal temperature gradient highlight detrimental effects of rising temperatures on its growth, demography and skeletal characteristics, suggesting that depression of photosynthesis at high temperatures might cause these negative effects. Here we test this hypothesis by analyzing, by means of pulse amplitude modulation fluorometry, the photosynthetic efficiency of B. europaea specimens exposed in aquaria to the annual range of temperatures experienced in the field (13°C, 18°C, and 28°C, and two extreme temperatures expected for 2100 as a consequence of global warming (29°C and 32°C. The indicators of photosynthetic performance analyzed (maximum and effective quantum yield showed that maximum efficiency was reached at 20.0-21.6°C, slightly higher than the annual mean temperature in the field (18°C. Photosynthetic efficiency decreased from 20.0°C to 13°C and even more strongly from 21.6°C to 32°C. An unusual form of bleaching was observed, with a maximum zooxanthellae density at 18°C that strongly decreased from 18°C to 32°C. Chlorophyll a concentration per zooxanthellae cell showed an opposite trend as it was minimal at 18°C and increased from 18°C to 32°C. Since the areal chlorophyll concentration is the product of the zooxanthellae density and its cellular content, these trends resulted in a homogeneous chlorophyll concentration per coral surface across temperature treatments. This confirms that B. europaea photosynthesis is progressively depressed at temperatures >21.6°C, supporting previous hypotheses raised by the studies on growth and demography of this species. This study also confirms the threats posed to this species by the ongoing seawater warming.

  5. Cereal grains for nutrition and health benefits: Overview of results from in vitro, animal and human studies in the HEALTHGRAIN project

    NARCIS (Netherlands)

    Björck, I.; Östman, E.; Kristensen, M.; Mateo Anson, N.; Price, R.K.; Haenen, G.R.M.M.; Havenaar, R.; Bach Knudsen, K.E.; Frid, A.; Mykkänen, H.; Welch, R.W.; Riccardi, G.

    2012-01-01

    Epidemiological studies have linked whole grain intake to the prevention of the metabolic syndrome, obesity and associated chronic diseases such as CVD and T2D. The Nutrition module within the HEALTHGRAIN project, included 10 partners and undertook in vitro, animal and human in vivo studies with the

  6. A hypothesis and a case-study projection of an influence of MJO modulation on boreal-summer tropical cyclogenesis in a warmer climate with a global non-hydrostatic model: a transition toward the central Pacific?

    Directory of Open Access Journals (Sweden)

    KAZUYOSHI eOOUCHI

    2014-02-01

    Full Text Available The eastward shift of the enhanced activity of tropical cyclone to the central Pacific is a robust projection result for a future warmer climate, and is shared by most of the state-of-the-art climate models. The shift has been argued to originate from the underlying El-Ñino like sea-surface temperature (SST forcing. This study explores the possibility that the change of the activity of the Madden-Julian Oscillation (MJO can be an additional, if not alternative, contributor to the shift, using the dataset of Yamada et al. (2010 from a global non-hydrostatic 14-km grid mesh time-slice experiment for a boreal-summer case. Within the case-study framework, we develop the hypothesis that an eastward shift of the high-activity area of the MJO, as manifested itself as the significant intra-seasonal modulation of the enhanced precipitation, is associated with the increased tropical cyclogenesis potential over the North central Pacific by regulating cyclonic relative vorticity and vertical shear. In contrast, the North Indian Ocean and maritime continent undergo relatively diminished genesis potential. An implication is that uncertainty in the future tropical cyclogenesis in some part of the Pacific and other ocean basins could be reduced if projection of the MJO and its connection with the underlying SST environment can be better understood and constrained by the improvement of climate models.

  7. FInal Technical Repot of the Project: Design and Implementation of Low-Power 10Gb/s/channel Laser/Silicon Photonics Modulator Drivers with SEU Tolerance for HL-LHC

    Energy Technology Data Exchange (ETDEWEB)

    Gui, Ping [Southern Methodist Univ., Dallas, TX (United States)

    2017-08-09

    During the funding period of this award from May 1, 2014 through March 30, 2016, we have accomplished the design, implementation and measurement results of two laser driver chips: LpGBLD10+ which is a low-power single-channel 10Gb/s laser driver IC, and LDQ10P, which is a 4x10Gb/s driver array chip for High Energy Physics (HEP) applications. With new circuit techniques, the driver consumes a record-low power consumption, 31 mW @10Gb/s/channel and occupies a small area of 400 µm × 1750 µm for the single-channel driver IC and 1900umx1700um for the LDQ10P chip. These characteristics allow for both the LpGBLD10+ ICs and LDQ10P suitable candidate for the Versatile Link PLUS (VL+) project, offering flexibility in configuring multiple Transmitters and receivers.

  8. Space Experiment Module (SEM)

    Science.gov (United States)

    Brodell, Charles L.

    1999-01-01

    The Space Experiment Module (SEM) Program is an education initiative sponsored by the National Aeronautics and Space Administration (NASA) Shuttle Small Payloads Project. The program provides nationwide educational access to space for Kindergarten through University level students. The SEM program focuses on the science of zero-gravity and microgravity. Within the program, NASA provides small containers or "modules" for students to fly experiments on the Space Shuttle. The experiments are created, designed, built, and implemented by students with teacher and/or mentor guidance. Student experiment modules are flown in a "carrier" which resides in the cargo bay of the Space Shuttle. The carrier supplies power to, and the means to control and collect data from each experiment.

  9. Study of Adsorbents for the Capture of CO2 in Post-combustion. Contribution of CIEMAT to Module 4 of the CENITCO2 Project

    International Nuclear Information System (INIS)

    Ruiz, E.; Marono, M.; Sanchez-Hervas, J. M.

    2010-01-01

    The main goal of CIEMAT within the CENIT-CO 2 project has been the development of a process for CO 2 capture from combustion flue gases by physical adsorption. In the first stage, screening studies to select promising adsorbents were carried out at laboratory scale, using simplified gas compositions. After that, pilot plant studies were performed using appropriate configurations of promising adsorbents under realistic conditions. CO 2 adsorption cyclic capacity of different adsorbents has been studied. Lastly, for the adsorbent selected as most promising, its cyclic efficiency and selectivity for CO 2 adsorption in the presence of other gaseous components (SO 2 , H 2 O, NO) of the combustion gas has been determined, as well as its performance along multiple sorption-desorption cycles in the presence of simulated combustion gas. None of the studied adsorbents, though being promising since they all have a capture efficiency of about 90%, seem to be susceptible of direct application to CO 2 capture by physical adsorption under conditions representative of gases exiting the desulphurization tower of conventional pulverized coal combustion plants. As an alternative, the development of hybrid and regenerable solid sorbents (physical-chemical adsorption) is proposed or the application of new technologies under development such as the electrochemical promotion in capturing CO 2 . (Author) 33 refs.

  10. LinkLights

    DEFF Research Database (Denmark)

    Grönvall, Erik; Kramp, Gunnar

    2011-01-01

    The project described in this paper aims to provide assistive tools to support elderly people affected by vestibular dysfunction (i.e. a form of balance disorder leading to dizziness and nausea) in their home-based rehabilitation activities. Challenges emerge as the rehabilitation moves from...... a supervised hospital setting to private homes. Our studies have shown that the elderly people are less motivated to perform the training at home. This paper presents a tangible, portable, two dimensional modular platform called LinkLights that has been developed to sustain the home-based rehabilitation......, giving clear guidelines what to do, adding motivational cues and elements of variation and surprise in the activity. Furthermore, a set of challenges for successful translocation of the therapeutic regimen from a supervised, hospital setting to an unsupervised home-based setting together with some early...

  11. Spatial Terahertz Modulator

    Science.gov (United States)

    Xie, Zhenwei; Wang, Xinke; Ye, Jiasheng; Feng, Shengfei; Sun, Wenfeng; Akalin, Tahsin; Zhang, Yan

    2013-11-01

    Terahertz (THz) technology is a developing and promising candidate for biological imaging, security inspection and communications, due to the low photon energy, the high transparency and the broad band properties of the THz radiation. However, a major encountered bottleneck is lack of efficient devices to manipulate the THz wave, especially to modulate the THz wave front. A wave front modulator should allow the optical or electrical control of the spatial transmission (or reflection) of an input THz wave and hence the ability to encode the information in a wave front. Here we propose a spatial THz modulator (STM) to dynamically control the THz wave front with photo-generated carriers. A computer generated THz hologram is projected onto a silicon wafer by a conventional spatial light modulator (SLM). The corresponding photo-generated carrier spatial distribution will be induced, which forms an amplitude hologram to modulate the wave front of the input THz beam. Some special intensity patterns and vortex beams are generated by using this method. This all-optical controllable STM is structure free, high resolution and broadband. It is expected to be widely used in future THz imaging and communication systems.

  12. Project Cost Estimation for Planning

    Science.gov (United States)

    2010-02-26

    For Nevada Department of Transportation (NDOT), there are far too many projects that ultimately cost much more than initially planned. Because project nominations are linked to estimates of future funding and the analysis of system needs, the inaccur...

  13. Development of a triple GEM readout module for a time projection chamber and measurement accuracies of hadronic Higgs branching fractions in ννH at a 350 GeV ILC

    International Nuclear Information System (INIS)

    Mueller, Felix

    2016-07-01

    The presented thesis addresses the development and evaluation of one of the detector concept for the International Linear Collider (ILC). The ILC is a planned, future electron-positron linear collider with a center-of-mass energy of up to 500 GeV in its first construction stage. The ILC is designed to perform precision measurements of the Standard Model, especially a model-independent reconstruction of the electroweak symmetry breaking sector. In 2012, the discovery of the Higgs boson at the LHC was an important first step and facilitates precision measurements of the Higgs boson coupling constants at the ILC. Challenging design goals have been defined for the ILC detectors in order to reach the desired measurement precisions. One of the two ILC detector concepts is the International Large Detector (ILD). A large Time Projection Chamber (TPC) is foreseen as the central tracking detector. In contrast to modern silicon tracking detectors, a TPC provides a large number of space points, and thus continuous sampling of the track parameters. Therefore, TPCs offer great pattern recognition capabilities including the identification of particle decays within the sensitive volume. The design momentum resolution of the ILD TPC is δ(1/p t )∼10 -4 GeV -1 which can be translated into a transverse spatial resolution of σ rφ ≤100 μm over the complete drift distance of 2.35 m. In the first part of the thesis, the development of a readout module for the TPC is presented which fulfills the performance requirements of the ILD TPC. The developed readout module is based on a stack of three ''Gas Electron Multiplier'' (GEM) foils and a pad readout. Thin ceramic grids are used as the support structure and spacers between the GEMs. The readout module was tested in a prototype TPC with a maximal drift distance of around 60 cm at the DESY II test beam. An additional guard ring at the upper edge of the module was introduced to minimize field distortions at the

  14. Irreducible Specht modules are signed Young modules

    OpenAIRE

    Hemmer, David J.

    2005-01-01

    Recently Donkin defined signed Young modules as a simultaneous generalization of Young and twisted Young modules for the symmetric group. We show that in odd characteristic, if a Specht module $S^\\lambda$ is irreducible, then $S^\\lambda$ is a signed Young module. Thus the set of irreducible Specht modules coincides with the set of irreducible signed Young modules. This provides evidence for our conjecture that the signed Young modules are precisely the class of indecomposable self-dual module...

  15. AVE project

    International Nuclear Information System (INIS)

    2004-01-01

    During 1998, ANAV began to optimize Human Resources to cope with the ERE and ANA-ANV integration. Project AVE was intended to achieve an orderly transfer of know-how, skills, attitudes and experiences. The most complex part was renovation of personnel with Operating Licenses. Nearly 140 people had joined the organization by late December 2003. This opportunity was seized to draw up a new Training Manual, and a common Initial Training Plan was designed for the two plants, accounting for the singularities of each one. The plan is divided into 5 modules: Common Training, Specific Training, PEI/CAT, Management, and on-the-job Training. The training environments were defined according to the nature of the capabilities to be acquired. Project AVE resulted in the merger of the Asco and Vandellos II Training services. (Author)

  16. Silicon Optical Modulator Simulation

    Directory of Open Access Journals (Sweden)

    Soon Thor LIM

    2015-04-01

    Full Text Available We developed a way of predicting and analyzing high speed optical modulator. Our research adopted a bottom-up approach to consider high-speed optical links using an eye diagram. Our method leverages on modular mapping of electrical characteristics to optical characteristics, while attaining the required accuracy necessary for device footprint approaching sub-micron scales where electrical data distribution varies drastically. We calculate for the bias dependent phase shift (2pi/mm and loss (dB/mm for the optical modulator based on the real and imaginary part of complex effective indices. Subsequently, combine effectively both the electrical and optical profiles to construct the optical eye diagram which is the essential gist of signal integrity of such devices.

  17. The CMS link system

    International Nuclear Information System (INIS)

    Vila, I.

    1999-01-01

    The Compact Muon Solenoid (CMS) is a multi-purpose detector that is going to be installed in the future Large Hadron Collider (LHC) at CERN. Muons are one of the main physical signatures of the expected new physics. The muons are going to be detected by the Central Tracker (CT) and the Muon Spectrometer (MS). Both, the CT and MS can provide an independent muon momentum measurement, but for all η and momentum values the highest precision for muon momentum measurement is achieved when the muon tracks are reconstructed using both tracking detectors. The calorimeters and the solenoid volumes separate about three meters the CT and the MS. It has been shown that the alignment of the CT with respect to the MS can not be guaranteed by a software alignment in a reasonable time scale. Therefore, an opto-mechanical system (the multipoint link system) have been designed to monitor, on-line, the relative position of both sub-detectors providing a common reference frame for both of them. The local alignment of the muon barrel spectrometer determines the relative position of the muon chambers with respect to themselves and also with respect to a carbon fiber rigid structure called MAB (Module for the Alignment of the Barrel). There are a total of 36 MABs distributed in the boundary planes of each muon spectrometer sector. This paper describes all the equipment and presents the principle of measurement. (author)

  18. New tools for Mendelian disease gene identification: PhenoDB variant analysis module; and GeneMatcher, a web-based tool for linking investigators with an interest in the same gene.

    Science.gov (United States)

    Sobreira, Nara; Schiettecatte, François; Boehm, Corinne; Valle, David; Hamosh, Ada

    2015-04-01

    Identifying the causative variant from among the thousands identified by whole-exome sequencing or whole-genome sequencing is a formidable challenge. To make this process as efficient and flexible as possible, we have developed a Variant Analysis Module coupled to our previously described Web-based phenotype intake tool, PhenoDB (http://researchphenodb.net and http://phenodb.org). When a small number of candidate-causative variants have been identified in a study of a particular patient or family, a second, more difficult challenge becomes proof of causality for any given variant. One approach to this problem is to find other cases with a similar phenotype and mutations in the same candidate gene. Alternatively, it may be possible to develop biological evidence for causality, an approach that is assisted by making connections to basic scientists studying the gene of interest, often in the setting of a model organism. Both of these strategies benefit from an open access, online site where individual clinicians and investigators could post genes of interest. To this end, we developed GeneMatcher (http://genematcher.org), a freely accessible Website that enables connections between clinicians and researchers across the world who share an interest in the same gene(s). © 2015 WILEY PERIODICALS, INC.

  19. The Øresund Link

    DEFF Research Database (Denmark)

    Møller, Jacob Steen

    "Øresundsbron" is the combined bridge and tunnel connecting Denmark and Sweden adjacent to Copenhagen. Øresundsbron was built and is operated by a consortium owned jointly by the Danish and Swedish states. The Link was inaugurated 1 July 2000 by the Queen of Denmark and the King of Sweden. The 16......-km link across the Sound could potentially impact the water exchange between the Baltic Sea and the North Sea, and the dredging activities during construction were a threat to the local marine environment. The public interest in the environmental issues together with a pro-active environmental policy...... of hydrodynamic modelling, on line monitoring and access to all environmental information through a GIS based information system. The public attitude towards the project in general and the environmental impact in particular shifted from a very sceptical one at the beginning of the project to a very positive one...

  20. Link invariants from finite Coxeter racks

    OpenAIRE

    Nelson, Sam; Wieghard, Ryan

    2008-01-01

    We study Coxeter racks over $\\mathbb{Z}_n$ and the knot and link invariants they define. We exploit the module structure of these racks to enhance the rack counting invariants and give examples showing that these enhanced invariants are stronger than the unenhanced rack counting invariants.

  1. The Versatile Link Demo Board (VLDB)

    International Nuclear Information System (INIS)

    Lesma, R. Martín; Alessio, F.; Barbosa, J.; Baron, S.; Caplan, C.; Leitao, P.; Porret, D.; Wyllie, K.; Pecoraro, C.

    2017-01-01

    The Versatile Link Demonstrator Board (VLDB) is the evaluation kit for the radiation-hard Optical Link ecosystem, which provides a 4.8 Gbps data transfer link for communication between front-end (FE) and back-end (BE) of the High Energy Physics experiments. It gathers the Versatile link main radiation-hard custom Application-Specific Integrated Circuits (ASICs) and modules: GBTx, GBT-SCA and VTRx/VTTx plus the FeastMP, a radiation-hard in-house designed DC-DC converter. This board is the first design allowing system-level tests of the Link with a complete interconnection of the constitutive components, allowing data acquisition, control and monitoring of FE devices with the GBT-SCA pair.

  2. Guidance system operations plan for manned LM earth orbital and lunar missions using program luminary 1E. Section 2: Data links

    Science.gov (United States)

    Hamilton, M. H.

    1972-01-01

    Data links for the guidance system of manned lunar module orbital and lunar missions are presented. Subjects discussed are: (1) digital uplink to lunar module, (2) lunar module liftoff time increment, (3) lunar module contiguous block update, (4) lunar module scatter update, (5) lunar module digital downlink, and (6) absolute addresses for update program.

  3. Signed Young Modules and Simple Specht Modules

    OpenAIRE

    Danz, Susanne; Lim, Kay Jin

    2015-01-01

    By a result of Hemmer, every simple Specht module of a finite symmetric group over a field of odd characteristic is a signed Young module. While Specht modules are parametrized by partitions, indecomposable signed Young modules are parametrized by certain pairs of partitions. The main result of this article establishes the signed Young module labels of simple Specht modules. Along the way we prove a number of results concerning indecomposable signed Young modules that are of independent inter...

  4. Linked data management

    CERN Document Server

    Hose, Katja; Schenkel, Ralf

    2014-01-01

    Linked Data Management presents techniques for querying and managing Linked Data that is available on today’s Web. The book shows how the abundance of Linked Data can serve as fertile ground for research and commercial applications. The text focuses on aspects of managing large-scale collections of Linked Data. It offers a detailed introduction to Linked Data and related standards, including the main principles distinguishing Linked Data from standard database technology. Chapters also describe how to generate links between datasets and explain the overall architecture of data integration systems based on Linked Data. A large part of the text is devoted to query processing in different setups. After presenting methods to publish relational data as Linked Data and efficient centralized processing, the book explores lookup-based, distributed, and parallel solutions. It then addresses advanced topics, such as reasoning, and discusses work related to read-write Linked Data for system interoperation. Desp...

  5. Memory Modulation

    NARCIS (Netherlands)

    Roozendaal, Benno; McGaugh, James L.

    2011-01-01

    Our memories are not all created equally strong: Some experiences are well remembered while others are remembered poorly, if at all. Research on memory modulation investigates the neurobiological processes and systems that contribute to such differences in the strength of our memories. Extensive

  6. In vitro glutathione peroxidase mimicry of ebselen is linked to its oxidation of critical thiols on key cerebral suphydryl proteins - A novel component of its GPx-mimic antioxidant mechanism emerging from its thiol-modulated toxicology and pharmacology.

    Science.gov (United States)

    Kade, I J; Balogun, B D; Rocha, J B T

    2013-10-25

    The antioxidant mechanism of ebselen in rats brain is largely linked with its glutathione peroxidase (GPx) rather than its peroxiredoxin mimicry ability. However, the precise molecular dynamics between the GPx-mimicry of ebselen and thiol utilization is yet to be fully clarified and thus still open. Herein, we investigated the influence of dithiothreitol (DTT) on the antioxidant action of ebselen against oxidant-induced cerebral lipid peroxidation and deoxyribose degradation. Furthermore, the critical inhibitory concentrations of ebselen on the activities of sulphydryl enzymes such as cerebral sodium pump, δ-aminolevulinic acid dehydratase (δ-ALAD) and lactate dehydrogenase (LDH) were also investigated. We observe that ebselen (at ≥42 μM) markedly inhibited lipid peroxidation in the presence and absence of DTT, whereas it inhibited deoxyribose degradation only in the presence of DTT. Furthermore, under in vitro conditions, ebselen inhibited the thiol containing enzymes; cerebral sodium pump (at ≥40 μM), δ-ALAD (≥10 μM) and LDH (≥1 μM) which were either prevented or reversed by DTT. However, the inhibition of the activities of these sulphydryl proteins in diabetic animals was prevented by ebselen. Summarily, it is apparent that the effective in vitro inhibitory doses of ebselen on the activity of the sulphydryl proteins are far less than its antioxidant doses. In addition, the presence of DTT is evidently a critical requirement for ebselen to effect its antioxidant action against deoxyribose degeradation and not lipid peroxidation. Consequently, we conclude that ebselen possibly utilizes available thiols on sulphydryl proteins to effect its GPx mimicry antioxidant action against lipid peroxidation in rat brain homogenate. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  7. Summer Principals'/Directors' Orientation Training Module.

    Science.gov (United States)

    Mata, Robert L.; Garcia, Richard L.

    Intended to provide current or potential project principals/directors with the basic knowledge, skills, abilities, and sensitivities needed to manage a summer migrant school project in the local educational setting, this module provides instruction in the project management areas of planning, preparation, control, and termination. The module…

  8. Manned Mission Space Exploration Utilizing a Flexible Universal Module

    Science.gov (United States)

    Humphries, P.; Barez, F.; Gowda, A.

    2018-02-01

    The proposed ASMS, Inc. "Flexible Universal Module" is in support of NASA's Deep Space Gateway project. The Flexible Universal Module provides a possible habitation or manufacturing environment in support of Manned Mission for Space Exploration.

  9. Final report: Efficient thyratron modulator project

    Energy Technology Data Exchange (ETDEWEB)

    R. J. Adler; R. J. Richter-Sand; C. W. Gregg

    1999-11-26

    The purpose of this program was to examine methods of increasing the efficiency of producing pulses to drive Klystrons in the 150 MW range. This may include 2 Klystrons in the 75 MW range. Specific methods of interest to improve the pulse efficiency were the use of a circuit to add energy to the tail of the pulse, the use of a bipyrimidal transformer, and the use of gas insulation as a means of improving the pulse shape. These methods were investigated using both thyratron and IGBT switching. The low cost designs developed in this work consisted of low voltage designs which don't require the oil immersion. These designs can be ''hot tuned'' based on the use of simple, tunable inductors.

  10. Final report: Efficient thyratron modulator project

    International Nuclear Information System (INIS)

    Adler, R.J.; Richter-Sand, R.J.; Gregg, C.W.

    1999-01-01

    The purpose of this program was to examine methods of increasing the efficiency of producing pulses to drive Klystrons in the 150 MW range. This may include 2 Klystrons in the 75 MW range. Specific methods of interest to improve the pulse efficiency were the use of a circuit to add energy to the tail of the pulse, the use of a bipyrimidal transformer, and the use of gas insulation as a means of improving the pulse shape. These methods were investigated using both thyratron and IGBT switching. The low cost designs developed in this work consisted of low voltage designs which don't require the oil immersion. These designs can be ''hot tuned'' based on the use of simple, tunable inductors

  11. FPGA based fast synchronous serial multi-wire links synchronization

    Science.gov (United States)

    Pozniak, Krzysztof T.

    2013-10-01

    The paper debates synchronization method of multi-wire, serial link of constant latency, by means of pseudo-random numbers generators. The solution was designed for various families of FPGA circuits. There were debated synchronization algorithm and functional structure of parameterized transmitter and receiver modules. The modules were realized in VHDL language in a behavioral form.

  12. A school and inquiry based project with Nordic student teachers

    DEFF Research Database (Denmark)

    Stougaard, Birgitte

    Álka is a framework involving teacher education institutions in the Nordic counties. This study describes the design of a module aiming at the establishment of a stronger nexus between research (theory) and teaching of science (practice) and to explore an issue relevant for the student teachers...... future professional life. The theme that was used for the research based project was: Nordic Children’s ideas about living things in the sea. Oral presentation at The 10th Nordic Research Symposium on Science Education (NFSUN), Linköbing, Sweden, June 2011....

  13. Customized PEC modules. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, Martin B. (DTI, Taastrup (Denmark))

    2012-07-01

    The purpose of the project ''Customized PEC modules'' was to move from the production hand-made individual DSCs (dye-sensitized solar cells) in the laboratory to the production of DSC modules in a semi-automated process. At the same time allowing sufficient variation in the product's specification for real tailoring of the product to the application. The tailoring can be related to the module's electrical output and size, but also to the possibility of designing patterns for decoration or communication purposes by playing around with the shape, size and layout of the individual cells forming the module. This was to be accomplished mainly by screen printing of DSC components on glass substrates at Mekoprint. For reaching this goal the work was divided into a number of steps. The central part of the work done was in the initial conception activity and the following manufacturing activity. An activity regarding optimization included several tasks of optimization and adaptation of the existing laboratory process for manufacturing of the DSCs. Finally, work focused on international activities was done. All the steps needed for the production of customized DSC modules have been demonstrated in this project. In combination with the development of a high performing printable sealant and sealing method all the prerequisites for producing customized DSC modules have been demonstrated. (LN)

  14. Compact Energy Conversion Module, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — This STTR project delivers a compact vibration-based Energy Conversion Module (ECM) that powers sensors for purposes such as structural health monitoring (SHM). NASA...

  15. Compact energy conversion module, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This STTR project delivers a compact vibration-based Energy Conversion Module (ECM) that powers sensors for purposes like structural health monitoring (SHM). NASA...

  16. Development of a triple GEM readout module for a time projection chamber and measurement accuracies of hadronic Higgs branching fractions in ννH at a 350 GeV ILC

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Felix

    2016-07-15

    The presented thesis addresses the development and evaluation of one of the detector concept for the International Linear Collider (ILC). The ILC is a planned, future electron-positron linear collider with a center-of-mass energy of up to 500 GeV in its first construction stage. The ILC is designed to perform precision measurements of the Standard Model, especially a model-independent reconstruction of the electroweak symmetry breaking sector. In 2012, the discovery of the Higgs boson at the LHC was an important first step and facilitates precision measurements of the Higgs boson coupling constants at the ILC. Challenging design goals have been defined for the ILC detectors in order to reach the desired measurement precisions. One of the two ILC detector concepts is the International Large Detector (ILD). A large Time Projection Chamber (TPC) is foreseen as the central tracking detector. In contrast to modern silicon tracking detectors, a TPC provides a large number of space points, and thus continuous sampling of the track parameters. Therefore, TPCs offer great pattern recognition capabilities including the identification of particle decays within the sensitive volume. The design momentum resolution of the ILD TPC is δ(1/p{sub t})∼10{sup -4} GeV{sup -1} which can be translated into a transverse spatial resolution of σ{sub rφ}≤100 μm over the complete drift distance of 2.35 m. In the first part of the thesis, the development of a readout module for the TPC is presented which fulfills the performance requirements of the ILD TPC. The developed readout module is based on a stack of three ''Gas Electron Multiplier'' (GEM) foils and a pad readout. Thin ceramic grids are used as the support structure and spacers between the GEMs. The readout module was tested in a prototype TPC with a maximal drift distance of around 60 cm at the DESY II test beam. An additional guard ring at the upper edge of the module was introduced to minimize field

  17. Asymmetrical Modulation for Uplink Communication in Cooperative Networks

    DEFF Research Database (Denmark)

    Zhang, Qi; Fitzek, Frank H.P.; Iversen, Villy Bæk

    2008-01-01

    -range links with neighboring mobile devices to form cooperative clusters. So far the physical communication over cellular links and over short-range links are separated in time or in frequency. Beyond this state of the art, we exploit a method, referred to as asymmetrical modulation, where a mobile device...

  18. Multichip module technology development

    International Nuclear Information System (INIS)

    Kapustinsky, J.S.; Boissevain, J.G.; Muck, R.C.; Smith, G.D.; Wong-Swanson, B.G.; Ziock, H.J.

    1997-01-01

    This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). A Multichip Module (MCM) was designed and submitted for fabrication to the Lockheed Martin foundry using a licensed process called High Density Interconnect (HDI). The HDI process uses thin film techniques to create circuit interconnect patterns on multiple layers of dielectric film which are deposited directly on top of unpackaged electronic die. This results in an optimally small package that approaches the area of the bare die themselves. This project tested the capability of the Lockheed Martin foundry to produce, in an HDI process, a complex mixed-mode (analog and digital) circuit on a single MCM substrate

  19. Electronic Resources Management Project Presentation 2012

    KAUST Repository

    Ramli, Rindra M.

    2012-01-01

    This presentation describes the electronic resources management project undertaken by the KAUST library. The objectives of this project is to migrate information from MS Sharepoint to Millennium ERM module. One of the advantages of this migration

  20. KNN BASED CLASSIFICATION OF DIGITAL MODULATED SIGNALS

    Directory of Open Access Journals (Sweden)

    Sajjad Ahmed Ghauri

    2016-11-01

    Full Text Available Demodulation process without the knowledge of modulation scheme requires Automatic Modulation Classification (AMC. When receiver has limited information about received signal then AMC become essential process. AMC finds important place in the field many civil and military fields such as modern electronic warfare, interfering source recognition, frequency management, link adaptation etc. In this paper we explore the use of K-nearest neighbor (KNN for modulation classification with different distance measurement methods. Five modulation schemes are used for classification purpose which is Binary Phase Shift Keying (BPSK, Quadrature Phase Shift Keying (QPSK, Quadrature Amplitude Modulation (QAM, 16-QAM and 64-QAM. Higher order cummulants (HOC are used as an input feature set to the classifier. Simulation results shows that proposed classification method provides better results for the considered modulation formats.

  1. Advanced structural materials for the suspension bridge solution of the project to establish a permanent link over the strait of Gibraltar; Materiales estructurales para la solucion puente, relacionados con el proyecto de enlace fijo a traves del estrecho de Gibraltar

    Energy Technology Data Exchange (ETDEWEB)

    Galligo Esteve, J. M.

    2015-07-01

    In 1995, the Spanish-moroccan Mixed Committee for the Gibraltar Strait Fixed Link selected the excavated tunnel solution, as preferred to the suspension bridge one. This was based on detailed scientific and technical studies. Nonetheless, further geology studies on the tunnel layout have detected sections of difficult excavation, which would entail increases in the length, the term of execution and the cost of the tunnel. Taking this into account, and due to the important technology development in bridge construction that has taken place over the last 20 years, the paper presents a state-of-the-art of the most advanced structural materials (high performance concrete, ultra-high performance concrete, suspension cables, structural steel, reinforcing and prestressing steel, stainless steel) available for an eventual reconsideration of the suspension bridge solution for the Gibraltar Strait Fixed Link. (Author)

  2. Project Solo; Newsletter Number Twenty.

    Science.gov (United States)

    Pittsburgh Univ., PA. Project Solo.

    Three Project Solo modules are presented. They are designed to teach the concepts of elementary matrix operation, matrix multiplication, and finite-state automata. Together with the module on communication matrices from Newsletter #17 they form a well motivated but structured path to expertise in this area. (JY)

  3. NSWEP: The Nova Scotia Wind Energy Project

    International Nuclear Information System (INIS)

    Hughes, L.; Little, T. A.

    2000-01-01

    A two-phase project, intended to educate Nova Scotians about the potential of wind power to help reduce the province's greenhouse gas emissions, thereby fulfilling a vital role in Canada's effort to mitigate climate change effects, is described. First phase of the project involves gathering of wind data; the second the installation of a number of wind turbines throughout the province. The data gathering phase encompasses site selection, the actual data gathering for a period of about ten months, data analysis, and creation of a four or five module educational program, to be linked with intermediate high school science, mathematics, geography and social studies curriculum objectives to provide an interdisciplinary examination of these topics, and convey a sense of the complexity of the issues involved. The second phase of the project is intended to promote the possible use of wind energy in the province by installing a number of 25 kW wind turbines at selected sites throughout the province, followed by the gathering analysis of data relating to the amount of power produced by the turbines, calculating the efficiency of turbines and comparing data with the data gathered in previous years. The project is expected to last at least five years, exposing about 4000 high school students to hands-on involvement with issues of climate change and sustainable energy. Parents and the community will be exposed to these same issues indirectly, aided by the relative proximity of the weather stations to schools and the strategic location of the wind turbines. 4 refs

  4. Cross connecting absorber module inlets of multiple boiler units

    International Nuclear Information System (INIS)

    Cirillo, A.J.; Sperber, P.K.; Belavadi, V.N.; Mukherji, A.

    1991-01-01

    The retrofitting of scrubbers downstream of existing balanced draft boilers is often accomplished by the addition of induced draft (ID) booster fans. By creating a common plenum between the ID fans and the ID booster fans of two or more boiler-absorber trains, absorber module capacity may be shared among multiple boiler units. At Harrison Power Station, three (3) 4,900,000 lb/hour boilers (640 MWe Gross) will be linked through a common plenum. This sharing capability precludes the need to add standby module capacity, thereby saving capital dollars and keeping project critical path schedules, which typically run through absorber procurement and construction, to a minimum. Through damper placement in the ductwork cross connections, unitized boiler-absorber module operation or common plenum operation may be obtained, thus providing both operational flexibility and reliability. Additionally, open plenum operation allows the removal of an absorber unit from service, while keeping its associated boiler on line, thereby precluding 'cold starts' and maintaining overall unit availabilities. As either unitized or common plenum operation is possible with the cross connection, the furnace draft control systems of each boiler must be examined for varying load operation and trip conditions. This paper addresses the means by which to analyze such cross connection operational scenarios while maintaining compliance with furnace flame out safety guidelines, and will discuss the physical design considerations, ramifications and benefits of same, with select emphasis on what is being implemented at the Harrison Power Station

  5. Research on Shore-Ship Photonic Link Performance for Two- Frequency-Band Signals

    Science.gov (United States)

    Zuo, Yanqin; Cong, Bo

    2016-02-01

    Ka and Ku bands links for shore-ship communications suffer limited bandwidth and high loss. In this paper, photonics-based links are proposed and modeled. The principle of phase modulation (PM) is elaborated and analyzed. It is showed that PM can effectively suppress high-order inter-modulation distortion (IMD), reduce the insert loss and improve the reliability of the system.

  6. Reflections on Post-16 Strategies in European Countries. Interim Report of the Leonardo da Vinci/Multiplier Effect Project III.3.a. Priority 2: Forging Links between Educational Establishments and Enterprises (1997-2000) ID 27009. Working Papers, No. 9.

    Science.gov (United States)

    Stenstrom, Marja-Leena, Ed.

    This four-part publication contains 19 papers on educational practices and promises for post-16 education in European countries. Part I, the introduction, contains these three papers: "Sharpening Post-16 Education Strategies: Building on the Results of the Previous Projects" (Johanna Lasonen); "'Parity of Esteem' and 'Integrated…

  7. MEMORY MODULATION

    Science.gov (United States)

    Roozendaal, Benno; McGaugh, James L.

    2011-01-01

    Our memories are not all created equally strong: Some experiences are well remembered while others are remembered poorly, if at all. Research on memory modulation investigates the neurobiological processes and systems that contribute to such differences in the strength of our memories. Extensive evidence from both animal and human research indicates that emotionally significant experiences activate hormonal and brain systems that regulate the consolidation of newly acquired memories. These effects are integrated through noradrenergic activation of the basolateral amygdala which regulates memory consolidation via interactions with many other brain regions involved in consolidating memories of recent experiences. Modulatory systems not only influence neurobiological processes underlying the consolidation of new information, but also affect other mnemonic processes, including memory extinction, memory recall and working memory. In contrast to their enhancing effects on consolidation, adrenal stress hormones impair memory retrieval and working memory. Such effects, as with memory consolidation, require noradrenergic activation of the basolateral amygdala and interactions with other brain regions. PMID:22122145

  8. Visualisierung von typisierten Links in Linked Data

    Directory of Open Access Journals (Sweden)

    Georg Neubauer

    2017-09-01

    Full Text Available Das Themengebiet der Arbeit behandelt Visualisierungen von typisierten Links in Linked Data. Die wissenschaftlichen Gebiete, die im Allgemeinen den Inhalt des Beitrags abgrenzen, sind das Semantic Web, das Web of Data und Informationsvisualisierung. Das Semantic Web, das von Tim Berners Lee 2001 erfunden wurde, stellt eine Erweiterung zum World Wide Web (Web 2.0 dar. Aktuelle Forschungen beziehen sich auf die Verknüpfbarkeit von Informationen im World Wide Web. Um es zu ermöglichen, solche Verbindungen wahrnehmen und verarbeiten zu können sind Visualisierungen die wichtigsten Anforderungen als Hauptteil der Datenverarbeitung. Im Zusammenhang mit dem Sematic Web werden Repräsentationen von zuhammenhängenden Informationen anhand von Graphen gehandhabt. Der Grund des Entstehens dieser Arbeit ist in erster Linie die Beschreibung der Gestaltung von Linked Data-Visualisierungskonzepten, deren Prinzipien im Rahmen einer theoretischen Annäherung eingeführt werden. Anhand des Kontexts führt eine schrittweise Erweiterung der Informationen mit dem Ziel, praktische Richtlinien anzubieten, zur Vernetzung dieser ausgearbeiteten Gestaltungsrichtlinien. Indem die Entwürfe zweier alternativer Visualisierungen einer standardisierten Webapplikation beschrieben werden, die Linked Data als Netzwerk visualisiert, konnte ein Test durchgeführt werden, der deren Kompatibilität zum Inhalt hatte. Der praktische Teil behandelt daher die Designphase, die Resultate, und zukünftige Anforderungen des Projektes, die durch die Testung ausgearbeitet wurden.

  9. PLC control of 50 MW klystron modulators

    International Nuclear Information System (INIS)

    Shang Lei; Liu Gongfa; Chen Liping; Lu Yeming; Hong Jun; Zhang Yi; Zhao Feng

    2004-01-01

    Upgrade project of the 50 MW klystron modulators of Hefei Light Source (HLS) was firstly introduced. PLC control system of modulators was employed to replace the old control and monitor system, which was based on relay logic circuit and manual operation method. the PLC system becomes a sub system of the new EPICS control system of HLS. Constant-current, switch-mode and high voltage power supplies were adopted to replace the old 50 Hz power supplies. The technology of modulators was improved and operation was more reliable. The design method, hardware and software of PLC control of modulators were described and the performance was presented. (authors)

  10. Linking the Human Resource Management in Education module to ...

    African Journals Online (AJOL)

    South African Journal of Education. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 23, No 3 (2003) >. Log in or Register to get access to full text downloads.

  11. Linking the Human Resource Management in Education module to ...

    African Journals Online (AJOL)

    Relevance of and interest in knowledge as critical components of the intellectual discourse have become increasingly evident to the academic community.The world of work has changed which implies that learners should be prepared for occupations requiring higher levels of knowledge and skills. The latter are not only ...

  12. Performance of Cat's Eye Modulating Retro-Reflectors for Free-Space Optical Communications

    National Research Council Canada - National Science Library

    Rabinovich, W. S; Goetz, P. G; Mahon, R; Swingen, L; Murphy, J; Gilbreath, G. C; Binari, S; Waluschka, E

    2004-01-01

    Modulating retro-reflectors (MRR) couple passive optical retro-reflectors with electro-optic modulators to allow free-space optical communication with a laser and pointing/acquisition/tracking system required on only one end of the link...

  13. Linking open vocabularies

    CERN Document Server

    Greifender, Elke; Seadle, Michael

    2013-01-01

    Linked Data (LD), Linked Open Data (LOD) and generating a web of data, present the new knowledge sharing frontier. In a philosophical context, LD is an evolving environment that reflects humankinds' desire to understand the world by drawing on the latest technologies and capabilities of the time. LD, while seemingly a new phenomenon did not emerge overnight; rather it represents the natural progression by which knowledge structures are developed, used, and shared. Linked Open Vocabularies is a significant trajectory of LD. Linked Open Vocabularies targets vocabularies that have traditionally b

  14. Tank Waste Remediation System Projects Document Control Plan

    International Nuclear Information System (INIS)

    Slater, G.D.; Halverson, T.G.

    1994-01-01

    The purpose of this Tank Waste Remediation System Projects Document Control Plan is to provide requirements and responsibilities for document control for the Hanford Waste Vitrification Plant (HWVP) Project and the Initial Pretreatment Module (IPM) Project

  15. Synchronic, optical transmission data link integrated with FPGA circuits (for TESLA LLRF control system)

    Energy Technology Data Exchange (ETDEWEB)

    Zielinski, J.S.

    2006-07-15

    The X-ray free-electron laser X-FEL that is being planned at the DESY research center in cooperation with European partners will produce high-intensity ultra-short X-ray flashes with the properties of laser light. This new light source, which can only be described in terms of superlatives, will open up a whole range of new possibilities for the natural sciences. It could also offer very promising opportunities for industrial users. SIMCON (SIMulator and CONtroller) is the project of the fast, low latency digital controller dedicated to the LLRF1 system in VUV FEL experiment It is being developed by the ELHEP2 group in the Institute of Electronic Systems at Warsaw University of Technology. The main purpose of the project is to create a controller to stabilize the vector sum of fields in cavities of one cryo-module in the experiment. The device can be also used as the simulator of the cavity and test bench for other devices. The synchronic, optical link project was made for the accelerator X-FEL laser TESLA, the LLRF control system experiment at DESY, Hamburg. The control and diagnostic data is transmitted up to 2.5Gbit/s through a plastic fiber in a distance up to a few hundred meters. The link is synchronized once after power up, and never resynchronized when data is transmitted with maximum speed. The one way link bit error rate is less then 10{sup -15}. The transceiver component written in VHDL that works in the dedicated Altera registered Stratix registered GX FPGA circuit. During the work in the PERG laboratory a 2,5Gbit/s serial link with the long vector parallel interface transceiver was created. Long-Data-Vector transceiver transmits 16bit vector each 8ns with 120ns latency. (orig.)

  16. Synchronic, optical transmission data link integrated with FPGA circuits (for TESLA LLRF control system)

    International Nuclear Information System (INIS)

    Zielinski, J.S.

    2006-05-01

    The X-ray free-electron laser X-FEL that is being planned at the DESY research center in cooperation with European partners will produce high-intensity ultra-short X-ray flashes with the properties of laser light. This new light source, which can only be described in terms of superlatives, will open up a whole range of new possibilities for the natural sciences. It could also offer very promising opportunities for industrial users. SIMCON (SIMulator and CONtroller) is the project of the fast, low latency digital controller dedicated to the LLRF1 system in VUV FEL experiment It is being developed by the ELHEP2 group in the Institute of Electronic Systems at Warsaw University of Technology. The main purpose of the project is to create a controller to stabilize the vector sum of fields in cavities of one cryo-module in the experiment. The device can be also used as the simulator of the cavity and test bench for other devices. The synchronic, optical link project was made for the accelerator X-FEL laser TESLA, the LLRF control system experiment at DESY, Hamburg. The control and diagnostic data is transmitted up to 2.5Gbit/s through a plastic fiber in a distance up to a few hundred meters. The link is synchronized once after power up, and never resynchronized when data is transmitted with maximum speed. The one way link bit error rate is less then 10 -15 . The transceiver component written in VHDL that works in the dedicated Altera registered Stratix registered GX FPGA circuit. During the work in the PERG laboratory a 2,5Gbit/s serial link with the long vector parallel interface transceiver was created. Long-Data-Vector transceiver transmits 16bit vector each 8ns with 120ns latency. (orig.)

  17. V123 Beam Synchronous Encoder Module

    International Nuclear Information System (INIS)

    Kerner, T.; Conkling, C. R.; Oerter, B.

    1999-01-01

    The V123 Synchronous Encoder Module transmits events to distributed trigger modules and embedded decoders around the RHIC rings where they are used to provide beam instrumentation triggers [1,2,3]. The RHIC beam synchronous event link hardware is mainly comprised of three VMEbus board designs, the central input modules (V201), and encoder modules (V123), and the distributed trigger modules (V124). Two beam synchronous links, one for each ring, are distributed via fiberoptic and fanned out via twisted wire pair cables. The V123 synchronizes with the RF system clock derived from the beam bucket frequency and a revolution fiducial pulse. The RF system clock is used to create the beam synchronous event link carrier and events are synchronized with the rotation fiducial. A low jitter RF clock is later recovered from this carrier by phase lock loops in the trigger modules. Prioritized hardware and software triggers fill up to 15 beam event code transmission slots per revolution while tracking the ramping RF acceleration frequency and storage frequency. The revolution fiducial event is always the first event transmitted which is used to synchronize the firing of the abort kicker and to locate the first bucket for decoders distributed about the ring

  18. Coherent Detection of Wavelength Division Multiplexed Phase-Modulated Radio-over-Fibre Signals

    DEFF Research Database (Denmark)

    Zibar, Darko; Yu, Xianbin; Peucheret, Christophe

    2008-01-01

    A WDM phase-modulated Radio-over-Fibre link using digital coherent detection is experimentally demonstrated. 3 times 50 Mb/s WDM transmission of a BPSK modulated 5 GHz RF carrier is achieved over 25 km.......A WDM phase-modulated Radio-over-Fibre link using digital coherent detection is experimentally demonstrated. 3 times 50 Mb/s WDM transmission of a BPSK modulated 5 GHz RF carrier is achieved over 25 km....

  19. Let's "Downscale" Linked Data

    NARCIS (Netherlands)

    Gueret, C.D.M.; de Boer, V.; Schlobach, K.S.

    2014-01-01

    Open data policies and linked data publication are powerful tools for increasing transparency, participatory governance, and accountability. The linked data community proudly emphasizes the economic and societal impact such technology shows. But a closer look proves that the design and deployment of

  20. Let's "Downscale" Linked Data

    NARCIS (Netherlands)

    Gueret, Christophe; de Boer, Victor; Schlobach, Stefan

    2014-01-01

    Open data policies and linked data publication are powerful tools for increasing transparency, participatory governance, and accountability. A closer look at linked data technologies, however, proves that their design and deployment exclude the majority of the world’s population. It will take small

  1. Weierstrass polynomials for links

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    1997-01-01

    There is a natural way of identifying links in3-space with polynomial covering spaces over thecircle. Thereby any link in 3-space can be definedby a Weierstrass polynomial over the circle. Theequivalence relation for covering spaces over thecircle is, however, completely different from...

  2. Functional and ultrastructural neuroanatomy of interactive intratectal/tectonigral mesencephalic opioid inhibitory links and nigrotectal GABAergic pathways: involvement of GABAA and mu1-opioid receptors in the modulation of panic-like reactions elicited by electrical stimulation of the dorsal midbrain.

    Science.gov (United States)

    Ribeiro, S J; Ciscato, J G; de Oliveira, R; de Oliveira, R C; D'Angelo-Dias, R; Carvalho, A D; Felippotti, T T; Rebouças, E C C; Castellan-Baldan, L; Hoffmann, A; Corrêa, S A L; Moreira, J E; Coimbra, N C

    2005-12-01

    the dlSC/dlPAG featuring close axo-somatic and axo-dendritic appositions in both locations. In addition, ultrastructural approaches show inhibitory axo-axonic synapses in MT and inhibitory axo-somatic/axo-axonic synapses in the SNpr. These findings, in addition to the psychopharmacological evidence for the interaction between opioid and GABAergic mechanisms in the cranial aspects of the MT as well as in the mesencephalic tegmentum, offer a neuroanatomical basis of a pre-synaptic opioid inhibition of GABAergic nigrotectal neurons modulating fear in defensive behavior-related structures of the cranial mesencephalon, in a short link, and through a major neural circuit, also in GABA-containing perikarya and axons of nigrotectal neurons.

  3. Theory of Abelian projection

    International Nuclear Information System (INIS)

    Ogilvie, M.C.

    1999-01-01

    Analytic methods for Abelian projection are developed. A number of results are obtained related to string tension measurements. It is proven that even without gauge fixing, Abelian projection yields string tensions of the underlying non-Abelian theory. Strong arguments are given for similar results in the case where gauge fixing is employed. The methods used emphasize that the projected theory is derived from the underlying non-Abelian theory rather than vice versa. In general, the choice of subgroup used for projection is not very important, and need not be Abelian. While gauge fixing is shown to be in principle unnecessary for the success of Abelian projection, it is computationally advantageous for the same reasons that improved operators, e.g., the use of fat links, are advantageous in Wilson loop measurements. Two other issues, Casimir scaling and the conflict between projection and critical universality, are also discussed. copyright 1999 The American Physical Society

  4. Scenarios, Policies and Impacts for the Linked Transport and Energy Systems - Results of the European TRIAS Project: Paper presented at TRA 2008 - Transport Research Arena Europe, Ljubljana, Slovenia, 21 - 25 April 2008

    OpenAIRE

    Schade, W.; Helfrich, N.; Krail, M.; Fiorello, D.; Fermi, F.; Schade, B.

    2008-01-01

    High oil prices and the growing awareness that this will not be a temporary but a permanent situation fosters the search for alternative fuels and new technologies to propel the transport system, which, so far, in Europe depends to more than 96% on fossil fuels. Two of these alternatives would be hydrogen and biofuels that both can be generated from a number of different sources including a number of non-fossil and renewable sources. The TRIAS project combined four models (ASTRA, POLES, VACLA...

  5. Interchip link system using an optical wiring method.

    Science.gov (United States)

    Cho, In-Kui; Ryu, Jin-Hwa; Jeong, Myung-Yung

    2008-08-15

    A chip-scale optical link system is presented with a transmitter/receiver and optical wire link. The interchip link system consists of a metal optical bench, a printed circuit board module, a driver/receiver integrated circuit, a vertical cavity surface-emitting laser/photodiode array, and an optical wire link composed of plastic optical fibers (POFs). We have developed a downsized POF and an optical wiring method that allows on-site installation with a simple annealing as optical wiring technologies for achieving high-density optical interchip interconnection within such devices. Successful data transfer measurements are presented.

  6. Fast Convolution Module (Fast Convolution Module)

    National Research Council Canada - National Science Library

    Bierens, L

    1997-01-01

    This report describes the design and realisation of a real-time range azimuth compression module, the so-called 'Fast Convolution Module', based on the fast convolution algorithm developed at TNO-FEL...

  7. Project Notes

    Science.gov (United States)

    School Science Review, 1978

    1978-01-01

    Presents sixteen project notes developed by pupils of Chipping Norton School and Bristol Grammar School, in the United Kingdom. These Projects include eight biology A-level projects and eight Chemistry A-level projects. (HM)

  8. Module theory, extending modules and generalizations

    CERN Document Server

    Tercan, Adnan

    2016-01-01

    The main focus of this monograph is to offer a comprehensive presentation of known and new results on various generalizations of CS-modules and CS-rings. Extending (or CS) modules are generalizations of injective (and also semisimple or uniform) modules. While the theory of CS-modules is well documented in monographs and textbooks, results on generalized forms of the CS property as well as dual notions are far less present in the literature. With their work the authors provide a solid background to module theory, accessible to anyone familiar with basic abstract algebra. The focus of the book is on direct sums of CS-modules and classes of modules related to CS-modules, such as relative (injective) ejective modules, (quasi) continuous modules, and lifting modules. In particular, matrix CS-rings are studied and clear proofs of fundamental decomposition results on CS-modules over commutative domains are given, thus complementing existing monographs in this area. Open problems round out the work and establish the...

  9. Multifunctional fiber-optic microwave links based on remote heterodyne detection

    DEFF Research Database (Denmark)

    Gliese, Ulrik Bo; Nielsen, Torben Nørskov; Nielsen, Søren Nørskov

    1998-01-01

    The multifunctionality of microwave links based on remote heterodyne detection (RHD) of signals from a dual-frequency laser transmitter is discussed and experimentally demonstrated in this paper. Typically, direct detection (DD) in conjunction with optical intensity modulation is used to implement...... fiber-optic microwave links. The resulting links are inherently transparent. As opposed to DD links, RHD links can perform radio-system functionalities such as modulation and frequency conversion in addition to transparency. All of these three functionalities are presented and experimentally...

  10. The Gigabit Link Interface Board (GLIB), a flexible system for the evaluation and use of GBT-based optical links

    CERN Document Server

    Vichoudis, P; Vasey, F; Joos, M; Hansen, M; Haas, S; Baron, S

    2010-01-01

    The Gigabit Link Interface Board (GLIB) is an evaluation platform and an easy entry point for users of high speed optical links in high energy physics experiments. Its intended use ranges from optical link evaluation in the laboratory to control, triggering and data acquisition from remote modules in beam or irradiation tests. The GLIB is an FPGA-based Advanced Mezzanine Card (AMC) conceived to serve a small and simple system residing either inside a Micro Telecommunications Computing Architecture (mu TCA) crate, or on a bench with a link to a PC. This paper presents the architecture of the GLIB, its features as well as examples of its use in different setups.

  11. Wide-band analog frequency modulation of optic signals using indirect techniques

    Science.gov (United States)

    Fitzmartin, D. J.; Balboni, E. J.; Gels, R. G.

    1991-01-01

    The wideband frequency modulation (FM) of an optical carrier by a radio frequency (RF) or microwave signal can be accomplished independent of laser type when indirect modulation is employed. Indirect modulators exploit the integral relation of phase to frequency so that phase modulators can be used to impress frequency modulation on an optical carrier. The use of integrated optics phase modulators, which are highly linear, enables the generation of optical wideband FM signals with very low intermodulation distortion. This modulator can be used as part of an optical wideband FM link for RF and microwave signals. Experimental results from the test of an indirect frequency modulator for an optical carrier are discussed.

  12. Advanced technologies for encryption of satellite links

    Science.gov (United States)

    McMahan, Sherry S.

    The use of encryption on satellite links is discussed. Advanced technology exists to provide transmission security for large earth station with data rates up to 50 megabits per second. One of the major concerns in the use of encryption equipment with very small aperture terminals (VSAT) is the key management issue and the related operational costs. The low cost requirement and the lack of physical protection of remote VSATs place severe constraints on the design of encryption equipment. Encryption may be accomplished by embedding a tamper proof encryption module into the baseband unit of each VSAT. VSAT networks are usually star networks where there is a single large earth station that serves as a hub and all satellite communications takes place between each VSAT and the hub earth station. The hub earth station has the secret master key of each VSAT. These master keys are used to downline load encrypted session keys to each VSAT. A more secure alternative is to use public key techniques where each embedded VSAT encryption module internally generates its own secret and public numbers. The secret number never leaves the module while the public number is sent to the hub at the time of initialization of the encryption module into the VSAT. Physical access control to encryption modules of VSAT systems can be implemented using passwords, smart cards or biometrics.

  13. INDICATIVE MODEL OF DEVIATIONS IN PROJECT

    Directory of Open Access Journals (Sweden)

    Олена Борисівна ДАНЧЕНКО

    2016-02-01

    Full Text Available The article shows the process of constructing the project deviations indicator model. It based on a conceptual model of project deviations integrated management (PDIM. During the project different causes (such as risks, changes, problems, crises, conflicts, stress lead to deviations of integrated project indicators - time, cost, quality, and content. For a more detailed definition of where in the project deviations occur and how they are dangerous for the whole project, it needs to develop an indicative model of project deviations. It allows identifying the most dangerous deviations that require PDIM. As a basis for evaluation of project's success has been taken famous model IPMA Delta. During the evaluation, IPMA Delta estimated project management competence of organization in three modules: I-Module ("Individuals" - a self-assessment personnel, P-module ("Projects" - self-assessment of projects and/or programs, and O-module ("Organization" - used to conduct interviews with selected people during auditing company. In the process of building an indicative model of deviations in the project, the first step is the assessment of project management in the organization by IPMA Delta. In the future, built cognitive map and matrix of system interconnections of the project, which conducted simulations and built a scale of deviations for the selected project. They determined a size and place of deviations. To identify the detailed causes of deviations in the project management has been proposed to use the extended system of indicators, which is based on indicators of project management model Project Excellence. The proposed indicative model of deviations in projects allows to estimate the size of variation and more accurately identify the place of negative deviations in the project and provides the project manager information for operational decision making for the management of deviations in the implementation of the project

  14. Aperture modulated arc therapy

    International Nuclear Information System (INIS)

    Crooks, S M; Wu, Xiaodong; Takita, C; Watzich, M; Xing Lei

    2003-01-01

    We show that it is possible to translate an intensity modulated radiation therapy (IMRT) treatment plan and deliver it as a single arc. This technique is referred to in this paper as aperture modulation arc therapy (AMAT). During this arc, the MLC leaves do not conform to the projection of the target PTV and the machine output of the accelerator has a constant value. Dose was calculated using the CORVUS 4.0 IMRT system, which uses a pencil beam dose algorithm, and treatments were delivered using a Varian 2100C/D Clinac. Results are presented for a head and neck and a prostate case, showing the equivalence of the IMRT and the translated AMAT delivery. For a prostate AMAT delivery, coronal plane film dose for the IMRT and AMAT deliveries agreed within 7.19 ± 6.62%. For a meningioma the coronal plane dose distributions were similar to a value of 4.6 ± 6.62%. Dose to the isocentre was measured as being within 2% of the planned value in both cases

  15. A study of the link between cosmic rays and clouds with a cloud chamber at the CERN PS

    CERN Document Server

    Fastrup, B; Lillestøl, Egil; Thorn, E; Bosteels, Michel; Gonidec, A; Harigel, G G; Kirkby, Jasper; Mele, S; Minginette, P; Nicquevert, Bertrand; Schinzel, D; Seidl, W; Grundsøe, P; Marsh, N D; Polny, J; Svensmark, H; Viisanen, Y; Kurvinen, K L; Orava, Risto; Hämeri, K; Kulmala, M; Laakso, I; Mäkelä, J M; O'Dowd, C D; Afrosimov, V; Basalaev, A; Panov, M; Laaksonen, B D; Joutsensaari, J; Ermakov, V; Makhmutov, V S; Maksumov, O; Pokrevsky, P; Stozhkov, Yu I; Svirzhevsky, N S; Carslaw, K; Yin, Y; Trautmann, T; Arnold, F; Wohlfrom, K H; Hagen, D; Schmitt, J; Whitefield, P; Aplin, K; Harrison, R G; Bingham, R; Close, Francis Edwin; Gibbins, C; Irving, A; Kellett, B; Lockwood, M; Petersen, D; Szymanski, W W; Wagner, P E; Vrtala, A; CERN. Geneva. SPS-PS Experiments Committee

    2000-01-01

    Recent satellite data have revealed a surprising correlation between galactic cosmic ray (GCR) intensity and the fraction of the Earth covered by clouds. If this correlation were to be established by a causal mechanism, it could provide a crucial step in understanding the long-sought mechanism connecting solar and climate variability. The Earth's climate seems to be remarkably sensitive to solar activity, but variations of the Sun's electromagnetic radiation appear to be too small to account for the observed climate variability. However, since the GCR intensity is strongly modulated by the solar wind, a GCR-cloud link may provide a sufficient amplifying mechanism. Moreover if this connection were to be confirmed, it could have profound consequences for our understanding of the solar contributions to the current global warming. The CLOUD (Cosmics Leaving OUtdoor Droplets) project proposes to test experimentally the existence a link between cosmic rays and cloud formation, and to understand the microphysical me...

  16. Link to paper

    Data.gov (United States)

    U.S. Environmental Protection Agency — Link to the paper. This dataset is associated with the following publication: Naile, J., A.W. Garrison, J. Avants, and J. Washington. Isomers/enantiomers of...

  17. Non-iterative geometric approach for inverse kinematics of redundant lead-module in a radiosurgical snake-like robot.

    Science.gov (United States)

    Omisore, Olatunji Mumini; Han, Shipeng; Ren, Lingxue; Zhang, Nannan; Ivanov, Kamen; Elazab, Ahmed; Wang, Lei

    2017-08-01

    Snake-like robot is an emerging form of serial-link manipulator with the morphologic design of biological snakes. The redundant robot can be used to assist medical experts in accessing internal organs with minimal or no invasion. Several snake-like robotic designs have been proposed for minimal invasive surgery, however, the few that were developed are yet to be fully explored for clinical procedures. This is due to lack of capability for full-fledged spatial navigation. In rare cases where such snake-like designs are spatially flexible, there exists no inverse kinematics (IK) solution with both precise control and fast response. In this study, we proposed a non-iterative geometric method for solving IK of lead-module of a snake-like robot designed for therapy or ablation of abdominal tumors. The proposed method is aimed at providing accurate and fast IK solution for given target points in the robot's workspace. n-1 virtual points (VPs) were geometrically computed and set as coordinates of intermediary joints in an n-link module. Suitable joint angles that can place the end-effector at given target points were then computed by vectorizing coordinates of the VPs, in addition to coordinates of the base point, target point, and tip of the first link in its default pose. The proposed method is applied to solve IK of two-link and redundant four-link modules. Both two-link and four-link modules were simulated with Robotics Toolbox in Matlab 8.3 (R2014a). Implementation result shows that the proposed method can solve IK of the spatially flexible robot with minimal error values. Furthermore, analyses of results from both modules show that the geometric method can reach 99.21 and 88.61% of points in their workspaces, respectively, with an error threshold of 1 mm. The proposed method is non-iterative and has a maximum execution time of 0.009 s. This paper focuses on solving IK problem of a spatially flexible robot which is part of a developmental project for abdominal

  18. The Missing Link

    DEFF Research Database (Denmark)

    Schultz, Laura Luise

    2014-01-01

    Paper presented at A Valentine to Gertrude Stein. The Reception of Gertrude Stein in the Arts and Humanities, held at the University of Copenhagen 8. - 10. May 2014, in collaboration with the universities of Ghent and Linköping......Paper presented at A Valentine to Gertrude Stein. The Reception of Gertrude Stein in the Arts and Humanities, held at the University of Copenhagen 8. - 10. May 2014, in collaboration with the universities of Ghent and Linköping...

  19. Linking world scan and image

    International Nuclear Information System (INIS)

    Timmer, H.; Alcamo, J.; Bollen, J.; Gielen, A.; Gerlach, R.; Den Ouden, A.; Zuidema, G.

    1995-01-01

    In march 1994 the Central Planning Bureau (CPB) in the Hague, the National Institute of Public Health and Environmental Protection (RIVM) in Bilthoven and the Institute of Environmental Studies (IES) in Amsterdam started the first phase of a joint research program aimed at creating integrated scenarios of the global economy, GHG emissions, and climate impacts. The goal of the first phase of this project was to design and test a linked version of the economic model WORLD SCAN of the former, and the climate model IMAGE 2 of the latter institute. This first phase has resulted in the planned test runs with an operational version of the linked models by May 1995. The experiences in the first year were encouraging, both in the scientific and the organizational sense. In a sense, a link was made between scientific disciplines: a coupling of disciplines concerning with global economic development and the global physical climate system is difficult and novel. The goal of the project was to integrate long-term economic developments and effects of climate change. Both the WORLD SCAN model and IMAGE 2 provide a consistent analysis of the global system, but from different perspectives. IMAGE 2 simulates climate change and its effects in a global context but treats the economic system as exogenous. WORLD SCAN covers the world economic system in a consistent manner but does not take into account the global environment. The links are constructed in the area of agriculture and energy. The basic idea is that WORLD SCAN determines demand and supply on economic principles, while IMAGE 2 provides information on changes of land area and average quality of productive land, and other damage costs based on its three sub-systems. The demand for energy is fed into IMAGE 2's Energy Industry subsystem (EIS), which in turn determines emissions of greenhouse gases. Furthermore, some additional output from WORLD SCAN on activity levels, prices and capital structure can be used to determine

  20. Experience with parallel optical link for the CDF silicon detector

    International Nuclear Information System (INIS)

    Hou, S.

    2003-01-01

    The Dense Optical Interface Module (DOIM) is a byte-wide optical link developed for the Run II upgrade of the CDF silicon tracking system [1]. The module consists of a transmitter with a laser-diode array for conversion of digitized detector signals to light outputs, a 22 m optical fiber ribbon cable for light transmission, and a receiver converting the light pulses back to electrical signals. We report on the design feature, characteristics, and radiation tolerance

  1. ITER Central Solenoid Module Fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Smith, John [General Atomics, San Diego, CA (United States)

    2016-09-23

    The fabrication of the modules for the ITER Central Solenoid (CS) has started in a dedicated production facility located in Poway, California, USA. The necessary tools have been designed, built, installed, and tested in the facility to enable the start of production. The current schedule has first module fabrication completed in 2017, followed by testing and subsequent shipment to ITER. The Central Solenoid is a key component of the ITER tokamak providing the inductive voltage to initiate and sustain the plasma current and to position and shape the plasma. The design of the CS has been a collaborative effort between the US ITER Project Office (US ITER), the international ITER Organization (IO) and General Atomics (GA). GA’s responsibility includes: completing the fabrication design, developing and qualifying the fabrication processes and tools, and then completing the fabrication of the seven 110 tonne CS modules. The modules will be shipped separately to the ITER site, and then stacked and aligned in the Assembly Hall prior to insertion in the core of the ITER tokamak. A dedicated facility in Poway, California, USA has been established by GA to complete the fabrication of the seven modules. Infrastructure improvements included thick reinforced concrete floors, a diesel generator for backup power, along with, cranes for moving the tooling within the facility. The fabrication process for a single module requires approximately 22 months followed by five months of testing, which includes preliminary electrical testing followed by high current (48.5 kA) tests at 4.7K. The production of the seven modules is completed in a parallel fashion through ten process stations. The process stations have been designed and built with most stations having completed testing and qualification for carrying out the required fabrication processes. The final qualification step for each process station is achieved by the successful production of a prototype coil. Fabrication of the first

  2. Modal noise impact in radio over fiber multimode fiber links.

    Science.gov (United States)

    Gasulla, I; Capmany, J

    2008-01-07

    A novel analysis is given on the statistics of modal noise for a graded-index multimode fiber (MMF) link excited by an analog intensity modulated laser diode. We present the speckle contrast as a function of the power spectrum of the modulated source and the transfer function of the MMF which behaves as an imperfect transversal microwave photonic filter. The theoretical results confirm that the modal noise is directly connected with the coherence properties of the optical source and show that the performance of high-frequency Radio Over Fiber (ROF) transmission through MMF links for short and middle reach distances is not substantially degraded by modal noise.

  3. Universal Reconfigurable Translator Module (URTM) Final Report

    Science.gov (United States)

    Leventhal, Edward; Machan, Roman; Jones, Rob

    2009-01-01

    This report describes the Universal Reconfigurable Translation Module, or URTM. The URTM was developed by Sigma Space Corporation for NASA in order to translate specific serial protocols, both logically and physically. At present, the prototype configuration has targeted MIL-STD-1553B (RT and BC), IEEE 1394b (Firewire), and ECSS-E-50-12A (SpaceWire). The objectives of this program were to study the feasibility of a configurable URTM to translate serial link data as might be used in a space-flight mission and to design, develop, document, and deliver an engineering prototype model of the URTM with a path to spaceflight. By simply connecting two of the three Physical Interface Modules (PIM) on either end of the RPTM (Reconfigurable Protocol Translator Module), the URTM then self configures via a library of interface translation functions, thereby allowing the two data links to communicate seamlessly.

  4. Perturbative improvement of staggered fermions using fat links

    International Nuclear Information System (INIS)

    Lee, Weonjong

    2002-01-01

    We study the possibility of improving staggered fermions using various fat links in order to reduce perturbative corrections to the gauge-invariant staggered fermion operators. We prove five theorems on SU(3) projection, triviality in renormalization, multiple SU(3) projections, uniqueness, and equivalence. As a result of these theorems, we show that, at the one-loop level, the renormalization of staggered fermion operators is identical between SU(3) projected Fat7 links and hypercubic links, as long as the action and operators are constructed by imposing the same perturbative improvement condition. In addition, we propose a new view of SU(3) projection as a tool of tadpole improvement for the staggered fermion doublers. As a conclusion, we present alternative choices of constructing fat links to improve the staggered fermion action and operators, which deserve further investigation

  5. Reduced multiplication modules

    Indian Academy of Sciences (India)

    if M is a von Neumann regular module (VNM); i.e., every principal submodule of M is a summand submodule. Also if M is an injective R-module, then M is a VNM. Keywords. Multiplication module; reduced module; minimal prime submodule;. Zariski topology; extremally disconnected. 1. Introduction. In this paper all rings are ...

  6. Wright Flyer Project

    Science.gov (United States)

    2004-01-01

    The wind tunnel test results have been published in the literature as summarized at the end of this report. As part of the education program, an introduction to engineering course module was designed and tested on 80 freshman engineering students at Old Dominion University. The five-week module required that five-person teams design, build and fly a radio-controlled airplane using only the wind tunnel data developed by the Wright brothers in 1902. That module is described in Sparks and Ash (2001). The Principal Investigator has co-authored one dozen publications resulting from this research, as listed at the end of this report. The Principal Investigator has given fourteen lectures on the Wright brother testing program and has appeared in two documentary television programs (summarized at the end of this report). Speaking invitations have continued since the completion of the project.

  7. Modulational effects in accelerators

    International Nuclear Information System (INIS)

    Satogata, T.

    1997-01-01

    We discuss effects of field modulations in accelerators, specifically those that can be used for operational beam diagnostics and beam halo control. In transverse beam dynamics, combined effects of nonlinear resonances and tune modulations influence diffusion rates with applied tune modulation has been demonstrated. In the longitudinal domain, applied RF phase and voltage modulations provide mechanisms for parasitic halo transport, useful in slow crystal extraction. Experimental experiences with transverse tune and RF modulations are also discussed

  8. R and D Towards Cryogenic Optical Links

    International Nuclear Information System (INIS)

    Christiansen, M.; Radeka, V.; Galea, R.; Gong, D.; Hou, S.; Lissauer, D.; Liu, C.; Liu, T.; Rehak, P.; Sondericker, J.; Stroynowski, R.; Su, D.-S.; Takacs, P.; Takai, H.; Techerniatine, V.; Teng, P.-K.; Thorn, C.; Xiang, A.C.; Ye, J.; Yu, B.

    2010-01-01

    A number of critical active and passive components of optical links have been tested at 77 K or lower temperatures, demonstrating potential development of optical links operating inside the liquid argon time projection chamber (LArTPC) detector cryostat. A ring oscillator, individual MOSFETs, and a high speed 16:1 serializer fabricated in a commercial 0.25-(micro)m silicon-on-sapphire CMOS technology continued to function from room temperature to 4.2 K, 15 K, and 77 K respectively. Three types of laser diodes lase from room temperature to 77 K. Optical fibers and optical connectors exhibited minute attenuation changes from room temperature to 77 K.

  9. Network-Centric Operations Case Study: Air-to-Air Combat With and Without Link 16

    National Research Council Canada - National Science Library

    Gonzales, Daniel; Hollywood, John; Kingston, Gina; Signori, David

    2005-01-01

    ...) Operational Special Project. In this exercise, the capabilities of F-15 air superiority aircraft equipped with voice-only communications were compared with F-15s equipped with voice and JTIDS Link 16 data link communications...

  10. Photovoltaic demonstration projects 2

    Energy Technology Data Exchange (ETDEWEB)

    Gillett, W B; Hacker, R J [Halcrow (William) and Partners, Swindon (UK); Kaut, W [eds.

    1989-01-01

    This book, the proceedings of the third Photovoltaic Contractors' Meeting organised by the Commission of the European Communities, Directorate-General for Energy provides an overview of the photovoltaic demonstration projects which have been supported by the Energy Directorate of the Commission of the European Communities since 1983. It includes reports by each of the contractors who submitted proposals in 1983, 1984 and 1985, describing progress with their projects. The different technologies which are being demonstrated concern the modules, the cabling of the array, structure design, storage strategy and power conditioning. The various applications include powering of houses, villages, recreation centres, water desalination, communications, dairy farms, water pumping and warning systems. (author).

  11. Link til hjemmesider

    DEFF Research Database (Denmark)

    Bervild, Charlotte

    2015-01-01

    Link til læringsobjekter/undervisningsportalhttp://videoportal.ucc.dk/channel/10492641/charlotte-bervilds-undervisninghttp://videoportal.ucc.dk/video/8248508/3d-printer-v-lektor-charlotte-bervildFotoblog:http://charlottebervild.blogspot.dk/2008/10/fotocollager-af-charlotte-bervild.html......Link til læringsobjekter/undervisningsportalhttp://videoportal.ucc.dk/channel/10492641/charlotte-bervilds-undervisninghttp://videoportal.ucc.dk/video/8248508/3d-printer-v-lektor-charlotte-bervildFotoblog:http://charlottebervild.blogspot.dk/2008/10/fotocollager-af-charlotte-bervild.html...

  12. Impaired Representation of Time in Schizophrenia Is Linked to Positive Symptoms and Cognitive Demand.

    Directory of Open Access Journals (Sweden)

    Jutta Peterburs

    Full Text Available Time processing critically relies on the mesencephalic dopamine system and striato-prefrontal projections and has thus been suggested to play a key role in schizophrenia. Previous studies have provided evidence for an acceleration of the internal clock in schizophrenia that may be linked to dopaminergic pathology. The present study aimed to assess the relationship between altered time processing in schizophrenia and symptom manifestation in 22 patients and 22 controls. Subjects were required to estimate the time needed for a visual stimulus to complete a horizontal movement towards a target position on trials of varying cognitive demand. It was hypothesized that patients - compared to controls - would be less accurate at estimating the movement time, and that this effect would be modulated by symptom manifestation and task difficulty. In line with the notion of an accelerated internal clock due to dopaminergic dysregulation, particularly patients with severe positive symptoms were expected to underestimate movement time. However, if altered time perception in schizophrenia was better explained in terms of cognitive deficits, patients with severe negative symptoms should be specifically impaired, while generally, task performance should correlate with measures of processing speed and cognitive flexibility. Patients underestimated movement time on more demanding trials, although there was no link to disease-related cognitive dysfunction. Task performance was modulated by symptom manifestation. Impaired estimation of movement time was significantly correlated with PANSS positive symptom scores, with higher positive symptom scores associated with stronger underestimation of movement time. The present data thus support the notion of a deficit in anticipatory and predictive mechanisms in schizophrenia that is modulated both by symptom manifestation and by cognitive demand.

  13. Fiber-linked interferometric pressure sensor

    Science.gov (United States)

    Beheim, G.; Fritsch, K.; Poorman, R. N.

    1987-01-01

    A fiber-optic pressure sensor is described which uses a diaphragm to modulate the mirror separation of a Fabry-Perot cavity (the sensing cavity). A multimode optical fiber delivers broadband light to the sensing cavity and returns the spectrally modulated light which the cavity reflects. The sensor's output spectrum is analyzed using a tunable Fabry-Perot cavity (the reference cavity) to determine the mismatch in the mirror separations of the two cavities. An electronic servo control uses this result to cause the mirror separation of the reference cavity to equal that of the sensing cavity. The displacement of the pressure-sensing diaphragm is then obtained by measuring the capacitance of the reference cavity's metal-coated mirrors. Relative to other fiber-optic sensors, an important advantage of this instrument is its high immunity to the effects of variations in both the transmissivity of the fiber link and the wavelength of the optical source.

  14. Reflective analogue optical link operating issues

    CERN Document Server

    Batten, Jeremy

    1996-01-01

    The proposed readout of analogue data from CMS tracker will use an optical fibre link. The choice of transmitter/receiver technology, however, has been the subject of intense research and development by the RD23 collaboration. One solution uses passive devices, multi-quantum well modulators, at the detector front end, and continuous wave driving lasers at the readout back end. This system has been tested at Imperial College. We report on the following: problems of noise associated with multimoded behaviour of a degraded laser; measurements of laser wavelength dependence on both drive current and temperature; and modulator reflectance dependence on laser wavelength. We extrapolate the findings to system issues, highlighting the degree of temperature control required of the driving laser.

  15. Helically linked mirror arrangement

    International Nuclear Information System (INIS)

    Ranjan, P.

    1986-08-01

    A scheme is described for helical linking of mirror sections, which endeavors to combine the better features of toroidal and mirror devices by eliminating the longitudinal loss of mirror machines, having moderately high average β and steady state operation. This scheme is aimed at a device, with closed magnetic surfaces having rotational transform for equilibrium, one or more axisymmetric straight sections for reduced radial loss, a simple geometrical axis for the links and an overall positive magnetic well depth for stability. We start by describing several other attempts at linking of mirror sections, made both in the past and the present. Then a description of our helically linked mirror scheme is given. This example has three identical straight sections connected by three sections having helical geometric axes. A theoretical analysis of the magnetic field and single-particle orbits in them leads to the conclusion that most of the passing particles would be confined in the device and they would have orbits independent of pitch angle under certain conditions. Numerical results are presented, which agree well with the theoretical results as far as passing particle orbits are concerned

  16. Transportation life cycle assessment (LCA) synthesis : life cycle assessment learning module series.

    Science.gov (United States)

    2015-03-12

    The Life Cycle Assessment Learning Module Series is a set of narrated, self-advancing slideshows on : various topics related to environmental life cycle assessment (LCA). This research project produced the first 27 of such modules, which : are freely...

  17. Force Modulator System

    Energy Technology Data Exchange (ETDEWEB)

    Redmond Clark

    2009-04-30

    Many metal parts manufacturers use large metal presses to shape sheet metal into finished products like car body parts, jet wing and fuselage surfaces, etc. These metal presses take sheet metal and - with enormous force - reshape the metal into a fully formed part in a manner of seconds. Although highly efficient, the forces involved in forming metal parts also damage the press itself, limit the metals used in part production, slow press operations and, when not properly controlled, cause the manufacture of large volumes of defective metal parts. To date, the metal-forming industry has not been able to develop a metal-holding technology that allows full control of press forces during the part forming process. This is of particular importance in the automotive lightweighting efforts under way in the US automotive manufacturing marketplace. Metalforming Controls Technology Inc. (MC2) has developed a patented press control system called the Force Modulator that has the ability to control these press forces, allowing a breakthrough in stamping process control. The technology includes a series of hydraulic cylinders that provide controlled tonnage at all points in the forming process. At the same time, the unique cylinder design allows for the generation of very high levels of clamping forces (very high tonnages) in very small spaces; a requirement for forming medium and large panels out of HSS and AHSS. Successful production application of these systems testing at multiple stamping operations - including Ford and Chrysler - has validated the capabilities and economic benefits of the system. Although this technology has been adopted in a number of stamping operations, one of the primary barriers to faster adoption and application of this technology in HSS projects is system cost. The cost issue has surfaced because the systems currently in use are built for each individual die as a custom application, thus driving higher tooling costs. This project proposed to better

  18. Links between nutrition and reproduction in cattle

    International Nuclear Information System (INIS)

    Marie, M.

    1999-01-01

    Situations in which nutrition modulates reproductive function, and targets involved, are identified, particularly in relation to initiation of cyclicity (at puberty, during the post-partum period or after induction of ovulation), fertility and induction of ovulation. The usefulness and pertinence of measurements of body weight variations, body condition score, nutritional balance or blood metabolites (glucose, ketone bodies, free fatty acids, cholesterol, urea and amino acids) to evaluate nutritional status in this context is considered. Leptin could play a central role in causal mechanisms linking nutrition and reproduction, in conjunction with somatotropic axis, insulin, opioids, and neuropeptide Y. (author)

  19. The Space Station Module Power Management and Distribution automation test bed

    Science.gov (United States)

    Lollar, Louis F.

    1991-01-01

    The Space Station Module Power Management And Distribution (SSM/PMAD) automation test bed project was begun at NASA/Marshall Space Flight Center (MSFC) in the mid-1980s to develop an autonomous, user-supportive power management and distribution test bed simulating the Space Station Freedom Hab/Lab modules. As the test bed has matured, many new technologies and projects have been added. The author focuses on three primary areas. The first area is the overall accomplishments of the test bed itself. These include a much-improved user interface, a more efficient expert system scheduler, improved communication among the three expert systems, and initial work on adding intermediate levels of autonomy. The second area is the addition of a more realistic power source to the SSM/PMAD test bed; this project is called the Large Autonomous Spacecraft Electrical Power System (LASEPS). The third area is the completion of a virtual link between the SSM/PMAD test bed at MSFC and the Autonomous Power Expert at Lewis Research Center.

  20. Module-Integrated Power Converters Based on Universal Dock

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, Patrick; Rodriguez, Fernando

    2015-03-13

    Solar power installations using alternating current photovoltaic (ACPV) modules have significant cost and performance advantages over systems using conventional solar modules and string inverters. ACPV modules have improved energy harvest due to module-level power point tracking and redundancy. More importantly, ACPV modules are easier and cheaper to install, lowering the total installed cost, indirect costs, and barriers to market entry. Furthermore, ACPV modules have communications and data logging capability, yielding module-level telemetry data that is useful in site diagnostics and other data applications. The products of these efforts were threefold. First, an advanced microinverter power topology was developed, modeled, simulated, and tested. Second, new microinverter enclosure concepts were developed and tested. Third, a new ACPV module prototype was constructed, combining the power topology and the enclosure concepts. SolarBridge filed for patents in each of these areas and is transitioning the project from a concept phase to full development.

  1. Design of inverters for the PHOTONERGY project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-08-01

    The PHOTONERGY project (the former SolcelleInverter project) was initiated on the 1st of September 2001, with a state-of-the-art analysis, which concluded into specifications. Based on this 23 topologies were analyzed in for efficiencies. The results from this analysis was five candidates which all showed a somewhat good efficiency. These five topologies were in further investigated by means of an initial design-iteration and simulations. Two different solutions were picked up in due to their high efficiency and low cost. 1. The standard full-bridge phase shifted DC/DC converter together with a standard DC/AC inverter, 2. A modified version of the novel Shimizu topology. A patent is pending on this modified version. These two inverters are in this document developed and made ready for prototyping. This includes design and selection of reactive- and switching-components, e.g. filter- and bulk-capacitors, low- and high-frequency inductors, high frequency transformers, MOSFETs and diodes. The design of auxiliary circuits is also included, e.g. gate drivers for the MOSFETs, measuring circuits for the grid-current and -voltage, PV-module-current and voltage, protection circuits, hardware near controllers and finally a switch mode power supply. However, the design of the various controllers, except the hardware near PV-current controller for the full bridge phase shifted converter, is not documented in this report but will come later on. This includes all controllers, e.g. maximum power point tracking for the PV-module, utility grid current controller, DC-link voltage controller, phase locked loops, and detection of islanding operation. All of these control loops are to be implemented in a micro-controller. (au)

  2. Physical Samples Linked Data in Action

    Science.gov (United States)

    Ji, P.; Arko, R. A.; Lehnert, K.; Bristol, S.

    2017-12-01

    Most data and metadata related to physical samples currently reside in isolated relational databases driven by diverse data models. How to approach the challenge for sharing, interchanging and integrating data from these difference relational databases motivated us to publish Linked Open Data for collections of physical samples, using Semantic Web technologies including the Resource Description Framework (RDF), RDF Query Language (SPARQL), and Web Ontology Language (OWL). In last few years, we have released four knowledge graphs concentrated on physical samples, including System for Earth Sample Registration (SESAR), USGS National Geochemical Database (NGDC), Ocean Biogeographic Information System (OBIS), and Earthchem Database. Currently the four knowledge graphs contain over 12 million facets (triples) about objects of interest to the geoscience domain. Choosing appropriate domain ontologies for representing context of data is the core of the whole work. Geolink ontology developed by Earthcube Geolink project was used as top level to represent common concepts like person, organization, cruise, etc. Physical sample ontology developed by Interdisciplinary Earth Data Alliance (IEDA) and Darwin Core vocabulary were used as second level to describe details about geological samples and biological diversity. We also focused on finding and building best tool chains to support the whole life cycle of publishing linked data we have, including information retrieval, linked data browsing and data visualization. Currently, Morph, Virtuoso Server, LodView, LodLive, and YASGUI were employed for converting, storing, representing, and querying data in a knowledge base (RDF triplestore). Persistent digital identifier is another main point we concentrated on. Open Researcher & Contributor IDs (ORCIDs), International Geo Sample Numbers (IGSNs), Global Research Identifier Database (GRID) and other persistent identifiers were used to link different resources from various graphs with

  3. Feed-Forward Control in Resonant DC Link Inverter

    OpenAIRE

    Apinan Aurasopon; Worawat Sa-ngiavibool

    2008-01-01

    This paper proposes a feed-forward control in resonant dc link inverter. The feed-forward control configuration is based on synchronous sigma-delta modulation. The simulation results showing the proposed technique can reject non-ideal dc bus improving the total harmonic distortion.

  4. Define Project

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas

    2005-01-01

    "Project" is a key concept in IS management. The word is frequently used in textbooks and standards. Yet we seldom find a precise definition of the concept. This paper discusses how to define the concept of a project. The proposed definition covers both heavily formalized projects and informally...... organized, agile projects. Based on the proposed definition popular existing definitions are discussed....

  5. Project Management

    DEFF Research Database (Denmark)

    Project Management Theory Meets Practice contains the proceedings from the 1st Danish Project Management Research Conference (DAPMARC 2015), held in Copenhagen, Denmark, on May 21st, 2015.......Project Management Theory Meets Practice contains the proceedings from the 1st Danish Project Management Research Conference (DAPMARC 2015), held in Copenhagen, Denmark, on May 21st, 2015....

  6. Achievable qualitative parameters of optical wireless links

    Czech Academy of Sciences Publication Activity Database

    Kolka, Z.; Wilfert, O.; Fišer, Ondřej

    2007-01-01

    Roč. 9, č. 8 (2007), s. 2419-2423 ISSN 1454-4164 R&D Projects: GA ČR(CZ) GA102/05/0571 Institutional research plan: CEZ:AV0Z30420517 Keywords : Free-space optical link * Transmission of atmosphere * Optical communication Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 0.827, year: 2007 http://inoe.inoe.ro/joam/index.php?option=magazine&op=view&idu=838&catid=16

  7. Problem Based Learning - Linking Students and Industry

    DEFF Research Database (Denmark)

    Fink, Flemming K.

    2006-01-01

    WG2_G4 Problem based learning – linking students and industry: a case study from Aalborg, Denmark Flemming K. Flink ELITE Aalborg University In Aalborg University, Denmark, all study programmes are organised around inter-disciplinary project work in groups. Up to 50% of the study work is problem-...... is essentially problem solving. The presentation looks into on campus POPBL and the Facilitated Work Based Learning (FBL) for continuing education. It also presents case examples of POPBL work....

  8. Project Management

    DEFF Research Database (Denmark)

    Pilkington, Alan; Chai, Kah-Hin; Le, Yang

    2015-01-01

    This paper identifies the true coverage of PM theory through a bibliometric analysis of the International Journal of Project Management from 1996-2012. We identify six persistent research themes: project time management, project risk management, programme management, large-scale project management......, project success/failure and practitioner development. These differ from those presented in review and editorial articles in the literature. In addition, topics missing from the PM BOK: knowledge management project-based organization and project portfolio management have become more popular topics...

  9. Project financing

    International Nuclear Information System (INIS)

    Cowan, A.

    1998-01-01

    Project financing was defined ('where a lender to a specific project has recourse only to the cash flow and assets of that project for repayment and security respectively') and its attributes were described. Project financing was said to be particularly well suited to power, pipeline, mining, telecommunications, petro-chemicals, road construction, and oil and gas projects, i.e. large infrastructure projects that are difficult to fund on-balance sheet, where the risk profile of a project does not fit the corporation's risk appetite, or where higher leverage is required. Sources of project financing were identified. The need to analyze and mitigate risks, and being aware that lenders always take a conservative view and gravitate towards the lowest common denominator, were considered the key to success in obtaining project financing funds. TransAlta Corporation's project financing experiences were used to illustrate the potential of this source of financing

  10. Urban rainfall estimation employing commercial microwave links

    Science.gov (United States)

    Overeem, Aart; Leijnse, Hidde; Uijlenhoet, Remko; ten Veldhuis, Marie-claire

    2015-04-01

    Urban areas often lack rainfall information. To increase the number of rainfall observations in cities, microwave links from operational cellular telecommunication networks may be employed. Although this new potential source of rainfall information has been shown to be promising, its quality needs to be demonstrated more extensively. In the Rain Sense kickstart project of the Amsterdam Institute for Advanced Metropolitan Solutions (AMS), sensors and citizens are preparing Amsterdam for future weather. Part of this project is rainfall estimation using new measurement techniques. Innovative sensing techniques will be utilized such as rainfall estimation from microwave links, umbrellas for weather sensing, low-cost sensors at lamp posts and in drainage pipes for water level observation. These will be combined with information provided by citizens in an active way through smartphone apps and in a passive way through social media posts (Twitter, Flickr etc.). Sensor information will be integrated, visualized and made accessible to citizens to help raise citizen awareness of urban water management challenges and promote resilience by providing information on how citizens can contribute in addressing these. Moreover, citizens and businesses can benefit from reliable weather information in planning their social and commercial activities. In the end city-wide high-resolution rainfall maps will be derived, blending rainfall information from microwave links and weather radars. This information will be used for urban water management. This presentation focuses on rainfall estimation from commercial microwave links. Received signal levels from tens of microwave links within the Amsterdam region (roughly 1 million inhabitants) in the Netherlands are utilized to estimate rainfall with high spatial and temporal resolution. Rainfall maps will be presented and compared to a gauge-adjusted radar rainfall data set. Rainfall time series from gauge(s), radars and links will be compared.

  11. Project descriptions

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    This part specifies the activities and project tasks of each project broken down according to types of financing, listing the current projects Lw 1 through 3 funded by long-term provisions (budget), the current projects LB 1 and 2, LG 1 through 5, LK1, LM1, and LU 1 through 6 financed from special funds, and the planned projects ZG 1 through 4 and ZU 1, also financed from special funds. (DG) [de

  12. Blind links, a big challenge in the linked data idea: Analysis of Persian Subject Headings

    Directory of Open Access Journals (Sweden)

    Atefeh Sharif

    2014-12-01

    Full Text Available In this survey, Linked data concept as exposing, sharing, and connecting pieces of data, information, and knowledge on the Semantic Web and some potential problems in converting Persian subject headings (PSHs Records into linked data were discussed. A data set (11233 records of PSHs was searched in three information retrieval systems including National Library of Iran (NLI online catalog, Library of Congress (LC online catalog and NOSA books. Correct links between Persian and English subject headings in the 9519 common records of two catalogs were recorded. The results indicate that the links between Persian and English subjects in 20% of records were failed. The maximum error was associated with the anonymous databases (6/7 % in NLI online catalog. It is recommended to preprocess the PSHs records before any conversion projects. It seems that, during the preprocessing, the potential errors could be identified and corrected.

  13. CDC 7600 module slice

    CERN Multimedia

    Each module contained 8 circuit cards for a total of about 300-500 uncovered transistors packaged with face plates so the Freon plates wouldn't touch the circuits. (cooling plates that surrounded each module).

  14. Website Policies / Important Links | DOepatents

    Science.gov (United States)

    Links Website Policies / Important Links Javascript Not Enabled OSTI Security Website Policies and first) Publication Date (oldest first) Close Clear All Find DOepatents Website Policies / Important Important Links Some links on this page may take you to non-federal websites. Their policies may differ from

  15. 80 Gbit/s 16-QAM Multicarrier THz Wireless Communication Link in the 400 GHz Band

    DEFF Research Database (Denmark)

    Jia, Shi; Yu, Xianbin; Hu, Hao

    2016-01-01

    We experimentally demonstrate a high-speed multicarrier THz wireless communication system operating in the 400 GHz band. The use of spectrally efficient 16-QAM modulation and broadband THz transceivers enable link data rates up to 80 Gbit/s....

  16. Ergodic Capacity Analysis of Free-Space Optical Links with Nonzero Boresight Pointing Errors

    KAUST Repository

    Ansari, Imran Shafique; Alouini, Mohamed-Slim; Cheng, Julian

    2015-01-01

    A unified capacity analysis of a free-space optical (FSO) link that accounts for nonzero boresight pointing errors and both types of detection techniques (i.e. intensity modulation/ direct detection as well as heterodyne detection) is addressed

  17. Pre-charging of module capacitors of MMC when the module ...

    Indian Academy of Sciences (India)

    Shamkant D Joshi

    The module capacitors need to be pre-charged, to power the control circuit. The problem faced while ... It consists of three legs to share a common DC link voltage. Each of these legs has ... Consider the stability of a system with only one capacitor with negative ..... number of wires because separate wires are not required for.

  18. Bottom-linked innovation

    DEFF Research Database (Denmark)

    Kristensen, Catharina Juul

    2018-01-01

    hitherto been paid little explicit attention, namely collaboration between middle managers and employees in innovation processes. In contrast to most studies, middle managers and employees are here both subjects of explicit investigation. The collaboration processes explored in this article are termed...... ‘bottom-linked innovation’. The empirical analysis is based on an in-depth qualitative study of bottom-linked innovation in a public frontline institution in Denmark. By combining research on employee-driven innovation and middle management, the article offers new insights into such collaborative......Employee-driven innovation is gaining ground as a strategy for developing sustainable organisations in the public and private sector. This type of innovation is characterised by active employee participation, and the bottom-up perspective is often emphasised. This article explores an issue that has...

  19. Hybrid Monte Carlo algorithm with fat link fermion actions

    International Nuclear Information System (INIS)

    Kamleh, Waseem; Leinweber, Derek B.; Williams, Anthony G.

    2004-01-01

    The use of APE smearing or other blocking techniques in lattice fermion actions can provide many advantages. There are many variants of these fat link actions in lattice QCD currently, such as flat link irrelevant clover (FLIC) fermions. The FLIC fermion formalism makes use of the APE blocking technique in combination with a projection of the blocked links back into the special unitary group. This reunitarization is often performed using an iterative maximization of a gauge invariant measure. This technique is not differentiable with respect to the gauge field and thus prevents the use of standard Hybrid Monte Carlo simulation algorithms. The use of an alternative projection technique circumvents this difficulty and allows the simulation of dynamical fat link fermions with standard HMC and its variants. The necessary equations of motion for FLIC fermions are derived, and some initial simulation results are presented. The technique is more general however, and is straightforwardly applicable to other smearing techniques or fat link actions

  20. CDC 6600 Cordwood Module

    CERN Multimedia

    1964-01-01

    The CDC 6600 cordwood module containing 64 silicon transistors. The module was mounted between two plates that were cooled conductive by a refrigeration unit via the front panel. The construction of this module uses the cord method, so called because the resistors seem to be stacked like cord between the two circuit boards in order to obtain a high density. The 6600 model contained nearly 6,000 such modules.