WorldWideScience

Sample records for project ctp represent

  1. The Central Trigger Processor (CTP)

    CERN Multimedia

    Franchini, Matteo

    2016-01-01

    The Central Trigger Processor (CTP) receives trigger information from the calorimeter and muon trigger processors, as well as from other sources of trigger. It makes the Level-1 decision (L1A) based on a trigger menu.

  2. CTP limitation increases expression of CTP synthase in Lactococcus lactis

    DEFF Research Database (Denmark)

    Jørgensen, C.M.; Hammer, Karin; Martinussen, Jan

    2003-01-01

    CTP synthase is encoded by the pyrG gene and catalyzes the conversion of UTP to CTP. A Lactococcus lactis pyrG mutant with a cytidine requirement was constructed, in which beta-galactosidase activity in a pyrG-lacLM transcriptional fusion was used to monitor gene expression of pyrG. A 10-fold...... decrease in the CTP pool induced by cytidine limitation was found to immediately increase expression of the L. lactis pyrG gene. The final level of expression of pyrG is 37-fold higher than the uninduced level. CTP limitation has pronounced effects on central cellular metabolism, and both RNA and protein...... for regulation of the pyrG gene. It is possible to fold the pyrG leader in an alternative structure that would prevent the formation of the terminator. We suggest a model for pyrG regulation in L. lactis, and probably in other gram-positive bacteria as well, in which pyrG expression is directly dependent...

  3. Representing Participation in ICT4D Projects

    DEFF Research Database (Denmark)

    Singh, J. P.; Flyverbom, Mikkel

    2016-01-01

    How do the discourses of participation inform deployment of information and communication technologies for development (ICT4D)? Discourses here mean narratives that assign roles to actors, and specify causes and outcomes for events. Based on the theory and practice of international development we......, depending on the context of their implementation, are permeated by multiple discourses about participation. Our four ideal types of participation discourses are, therefore, useful starting points to discuss the intricate dynamics of participation in ICT4D projects....

  4. The ALICE Central Trigger Processor (CTP) upgrade

    International Nuclear Information System (INIS)

    Krivda, M.; Alexandre, D.; Barnby, L.S.; Evans, D.; Jones, P.G.; Jusko, A.; Lietava, R.; Baillie, O. Villalobos; Pospíšil, J.

    2016-01-01

    The ALICE Central Trigger Processor (CTP) at the CERN LHC has been upgraded for LHC Run 2, to improve the Transition Radiation Detector (TRD) data-taking efficiency and to improve the physics performance of ALICE. There is a new additional CTP interaction record sent using a new second Detector Data Link (DDL), a 2 GB DDR3 memory and an extension of functionality for classes. The CTP switch has been incorporated directly onto the new LM0 board. A design proposal for an ALICE CTP upgrade for LHC Run 3 is also presented. Part of the development is a low latency high bandwidth interface whose purpose is to minimize an overall trigger latency

  5. Analytical similarity assessment of rituximab biosimilar CT-P10 to reference medicinal product.

    Science.gov (United States)

    Lee, Kyoung Hoon; Lee, Jihun; Bae, Jin Soo; Kim, Yeon Jung; Kang, Hyun Ah; Kim, Sung Hwan; Lee, So Jung; Lim, Ki Jung; Lee, Jung Woo; Jung, Soon Kwan; Chang, Shin Jae

    2018-04-01

    CT-P10 (Truxima™) was recently approved as the world's first rituximab biosimilar product in the European Union (EU) and South Korea. To demonstrate biosimilarity of CT-P10 with the reference medicinal product (RMP), extensive 3-way similarity assessment has been conducted between CT-P10, EU-Rituximab and US-Rituximab, focusing on the physicochemical and biological quality attributes. A multitude of state-of-the-art analyses revealed that CT-P10 has identical primary and higher order structures compared to the original product. Purity/impurity profiles of CT-P10 measured by the levels of aggregates, fragments, non-glycosylated form and process-related impurities were also found to be comparable with those of RMPs. In terms of the post-translational modification, CT-P10 contains slightly less N-terminal pyro-glutamate variant, which has been known not to affect product efficacy or safety. Oligosaccharide profiling has revealed that, although CT-P10 contains the same conserved glycan species and relative proportion with the RMPs, the content of total afucosylated glycan in CT-P10 was slightly higher than in EU- or US-Rituximab. Nevertheless, the effect of the observed level of afucosylation in CT-P10 drug product on Fc receptor binding affinity or antibody-dependent cell-mediated cytotoxicity was found to be negligible based on the spiking study with highly afucosylated sample. Arrays of biological assays representative of known and putative mechanisms of action for rituximab have shown that biological activities of CT-P10 are within the quality range of RMPs. Recent results of clinical studies have further confirmed that the CT-P10 exhibits equivalent clinical efficacy and safety profiles compared to EU- and US-Rituximab. The current 3-way similarity assessment together with clinical study results confidently demonstrate that CT-P10 is highly similar with EU- and US-Rituximab in terms of physicochemical properties, biological activities, efficacy, and safety for

  6. CTP synthase forms cytoophidia in the cytoplasm and nucleus

    International Nuclear Information System (INIS)

    Gou, Ke-Mian; Chang, Chia-Chun; Shen, Qing-Ji; Sung, Li-Ying; Liu, Ji-Long

    2014-01-01

    CTP synthase is an essential metabolic enzyme responsible for the de novo synthesis of CTP. Multiple studies have recently showed that CTP synthase protein molecules form filamentous structures termed cytoophidia or CTP synthase filaments in the cytoplasm of eukaryotic cells, as well as in bacteria. Here we report that CTP synthase can form cytoophidia not only in the cytoplasm, but also in the nucleus of eukaryotic cells. Both glutamine deprivation and glutamine analog treatment promote formation of cytoplasmic cytoophidia (C-cytoophidia) and nuclear cytoophidia (N-cytoophidia). N-cytoophidia are generally shorter and thinner than their cytoplasmic counterparts. In mammalian cells, both CTP synthase 1 and CTP synthase 2 can form cytoophidia. Using live imaging, we have observed that both C-cytoophidia and N-cytoophidia undergo multiple rounds of fusion upon glutamine analog treatment. Our study reveals the coexistence of cytoophidia in the cytoplasm and nucleus, therefore providing a good opportunity to investigate the intracellular compartmentation of CTP synthase. - Highlights: • CTP synthase forms cytoophidia not only in the cytoplasm but also in the nucleus. • Glutamine deprivation and Glutamine analogs promotes cytoophidium formation. • N-cytoophidia exhibit distinct morphology when compared to C-cytoophidia. • Both CTP synthase 1 and CTP synthase 2 form cytoophidia in mammalian cells. • Fusions of cytoophidia occur in the cytoplasm and nucleus

  7. CTP synthase forms cytoophidia in the cytoplasm and nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Gou, Ke-Mian [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); State Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193 (China); Chang, Chia-Chun [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Shen, Qing-Ji [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); Sung, Li-Ying, E-mail: liyingsung@ntu.edu.tw [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan, ROC (China); Liu, Ji-Long, E-mail: jilong.liu@dpag.ox.ac.uk [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom)

    2014-04-15

    CTP synthase is an essential metabolic enzyme responsible for the de novo synthesis of CTP. Multiple studies have recently showed that CTP synthase protein molecules form filamentous structures termed cytoophidia or CTP synthase filaments in the cytoplasm of eukaryotic cells, as well as in bacteria. Here we report that CTP synthase can form cytoophidia not only in the cytoplasm, but also in the nucleus of eukaryotic cells. Both glutamine deprivation and glutamine analog treatment promote formation of cytoplasmic cytoophidia (C-cytoophidia) and nuclear cytoophidia (N-cytoophidia). N-cytoophidia are generally shorter and thinner than their cytoplasmic counterparts. In mammalian cells, both CTP synthase 1 and CTP synthase 2 can form cytoophidia. Using live imaging, we have observed that both C-cytoophidia and N-cytoophidia undergo multiple rounds of fusion upon glutamine analog treatment. Our study reveals the coexistence of cytoophidia in the cytoplasm and nucleus, therefore providing a good opportunity to investigate the intracellular compartmentation of CTP synthase. - Highlights: • CTP synthase forms cytoophidia not only in the cytoplasm but also in the nucleus. • Glutamine deprivation and Glutamine analogs promotes cytoophidium formation. • N-cytoophidia exhibit distinct morphology when compared to C-cytoophidia. • Both CTP synthase 1 and CTP synthase 2 form cytoophidia in mammalian cells. • Fusions of cytoophidia occur in the cytoplasm and nucleus.

  8. Fabrication of CTP/HAp novel gradient composite bioceramics

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Calcium-titanium-phosphate(CaTi4(PO4)6, CTP)/hydroxyapatite(HAp) is a kind of novel gradient composite bioceramics,which has excellent biocompatibility and bioactivity. CTP ceramic film was synthesized one-step on the surface of titanium using micro-arc oxidation(MAO). The CTP/HAp composite bioceramics were prepared by soaking CTP film in HAp inducing solution for several days. XRD, SEM and EDX were used to characterize the bio-ceramic films phase and composition, morphology and component. The influence of electrolyte molar ratio of Ca to P and the current density to the synthesis of film was studied, and the optimized value of parameters above were 1/6 and 15A/dm2. The parameters of HAp inducing solution, such as component and pH value were also studied and the best pH value which is adjusted by NaOH is 6.4.

  9. The ATLAS Level-1 Central Trigger Processor (CTP)

    CERN Document Server

    Spiwoks, Ralf; Ellis, Nick; Farthouat, P; Gällnö, P; Haller, J; Krasznahorkay, A; Maeno, T; Pauly, T; Pessoa-Lima, H; Resurreccion-Arcas, I; Schuler, G; De Seixas, J M; Torga-Teixeira, R; Wengler, T

    2005-01-01

    The ATLAS Level-1 Central Trigger Processor (CTP) combines information from calorimeter and muon trigger processors and makes the final Level-1 Accept (L1A) decision on the basis of lists of selection criteria (trigger menus). In addition to the event-selection decision, the CTP also provides trigger summary information to the Level-2 trigger and the data acquisition system. It further provides accumulated and bunch-by-bunch scaler data for monitoring of the trigger, detector and beam conditions. The CTP is presented and results are shown from tests with the calorimeter adn muon trigger processors connected to detectors in a particle beam, as well as from stand-alone full-system tests in the laboratory which were used to validate the CTP.

  10. Assessment of urgent impacts of greenhouse gas emissions—the climate tipping potential (CTP)

    DEFF Research Database (Denmark)

    Jørgensen, Susanne Vedel; Hauschild, Michael Zwicky; Nielsen, Per H.

    2014-01-01

    The impact of anthropogenic greenhouse gas (GHG) emissions on climate change receives much focus today. This impact is however often considered only in terms of global warming potential (GWP), which does not take into account the need for staying below climatic target levels, in order to avoid...... passing critical climate tipping points. Some suggestions to include a target level in climate change impact assessment have been made, but with the consequence of disregarding impacts beyond that target level. The aim of this paper is to introduce the climate tipping impact category, which represents...... as on the chosen climatic target level and background scenario for atmospheric GHG concentration development. In order to enable direct application in life cycle assessment (LCA), CTP characterisation factors are presented for the three main anthropogenic GHGs, CO2, CH4 and N2O.The CTP metric distinguishes...

  11. Expression of Human CTP Synthetase in Saccharomyces cerevisiae Reveals Phosphorylation by Protein Kinase A*

    Science.gov (United States)

    Han, Gil-Soo; Sreenivas, Avula; Choi, Mal-Gi; Chang, Yu-Fang; Martin, Shelley S.; Baldwin, Enoch P.; Carman, George M.

    2005-01-01

    CTP synthetase (EC 6.3.4.2, UTP: ammonia ligase (ADP-forming)) is an essential enzyme in all organisms; it generates the CTP required for the synthesis of nucleic acids and membrane phospholipids. In this work we showed that the human CTP synthetase genes, CTPS1 and CTPS2, were functional in Saccharomyces cerevisiae and complemented the lethal phenotype of the ura7Δ ura8Δ mutant lacking CTP synthetase activity. The expression of the CTPS1-and CTPS2-encoded human CTP synthetase enzymes in the ura7Δ ura8Δ mutant was shown by immunoblot analysis of CTP synthetase proteins, the measurement of CTP synthetase activity, and the synthesis of CTP in vivo. Phosphoamino acid and phosphopeptide mapping analyses of human CTP synthetase 1 isolated from 32Pi-labeled cells revealed that the enzyme was phosphorylated on multiple serine residues in vivo. Activation of protein kinase A activity in yeast resulted in transient increases (2-fold) in the phosphorylation of human CTP synthetase 1 and the cellular level of CTP. Human CTP synthetase 1 was also phosphorylated by mammalian protein kinase A in vitro. Using human CTP synthetase 1 purified from Escherichia coli as a substrate, protein kinase A activity was dose- and time-dependent, and dependent on the concentrations of CTP synthetase1 and ATP. These studies showed that S. cerevisiae was useful for the analysis of human CTP synthetase phosphorylation. PMID:16179339

  12. Evaluation of Representative Smart Grid Investment Project Technologies: Demand Response

    Energy Technology Data Exchange (ETDEWEB)

    Fuller, Jason C.; Prakash Kumar, Nirupama; Bonebrake, Christopher A.

    2012-02-14

    This document is one of a series of reports estimating the benefits of deploying technologies similar to those implemented on the Smart Grid Investment Grant (SGIG) projects. Four technical reports cover the various types of technologies deployed in the SGIG projects, distribution automation, demand response, energy storage, and renewables integration. A fifth report in the series examines the benefits of deploying these technologies on a national level. This technical report examines the impacts of a limited number of demand response technologies and implementations deployed in the SGIG projects.

  13. Representing with Light. Video Projection Mapping for Cultural Heritage

    Science.gov (United States)

    Barbiani, C.; Guerra, F.; Pasini, T.; Visonà, M.

    2018-05-01

    In this paper, we describe a cross-disciplinary process that uses photogrammetric surveys as a precise basis for video projection mapping techniques. Beginning with a solid basis that uses geoinformatics technologies, such as laser scanning and photogrammetric survey, the method sets, as a first step, the physical and geometrical acquisition of the object. Precision and accuracy are the basics that allow the analysis of the artwork, both at a small or large scale, to evaluate details and correspondences. Testing contents at different scales of the object, using 3D printed replicas or real architectures is the second step of the investigation.The core of the process is the use of equations of collinearity into an interactive system such as Max 7, a visual programming language for music and multimedia, in order to facilitate operators to have a fast image correction, directly inside the interactive software. Interactivity gives also the opportunity to easily configure a set of actions to let the spectators to directly change and control the animation content. The paper goes through the different phases of the research, analysing the results and the progress through a series of events on real architecture and experiments on 3d printed models to test the level of involvement of the audience and the flexibility of the system in terms of content.The idea of using the collinearity equation inside da software Max 7 was developed for the M.Arch final Thesis by Massimo Visonà and Tommaso Pasini of the University of Venice (IUAV) in collaboration with the Digital Exhibit Postgraduate Master Course (MDE Iuav).

  14. Adaptation of Regional Representative Soil Project and Soil Judging for Cameroon

    Science.gov (United States)

    Che, Celestine Akuma

    2013-01-01

    Representative regional soils have agricultural, cultural, economic, environmental, and historical importance to Cameroon. Twenty seven regional representative soils have been identified in Cameroon. A set of laboratory exercises, assignments and exam questions have been developed utilizing the Regional Representative Soil Project (RRSP) that…

  15. A framework for extracting and representing project knowledge contexts using topic models and dynamic knowledge maps

    Science.gov (United States)

    Xu, Jin; Li, Zheng; Li, Shuliang; Zhang, Yanyan

    2015-07-01

    There is still a lack of effective paradigms and tools for analysing and discovering the contents and relationships of project knowledge contexts in the field of project management. In this paper, a new framework for extracting and representing project knowledge contexts using topic models and dynamic knowledge maps under big data environments is proposed and developed. The conceptual paradigm, theoretical underpinning, extended topic model, and illustration examples of the ontology model for project knowledge maps are presented, with further research work envisaged.

  16. A review of the literature analyzing benefits and concerns of infliximab biosimilar CT-P13 for the treatment of rheumatologic diseases: focus on interchangeability.

    Science.gov (United States)

    Becciolini, Andrea; Raimondo, Maria Gabriella; Crotti, Chiara; Agape, Elena; Biggioggero, Martina; Favalli, Ennio Giulio

    2017-01-01

    The introduction of biological agents drastically changed the treatment paradigm of inflammatory arthritides, ameliorating the natural history of the diseases but concomitantly increasing the drug costs due to the manufacturing process. On this concern, biosimilar drugs may represent a valid option for reducing this elevated cost and increasing the availability of these highly effective treatments. Recently, CT-P13, the first biosimilar of infliximab, has been approved with the same indications established for the reference product (RP), and its daily use is progressively increasing. However, the experience with biosimilar drugs in the field of rheumatology is still limited, raising potential doubts and concerns on their correct management in real-life settings. Comparability analysis between CT-P13 and its RP was evaluated in equivalence randomized controlled trials (RCTs) - PLANETRA and PLANETAS - performed on patients with rheumatoid arthritis and axial spondylitis, respectively. CT-P13 and RP showed similar profile in terms of quality, biological activity, safety, immunogenicity, and efficacy. However, the interchangeability between infliximab RP and its biosimilar still represents the most challenging issue because of a lack of a long-lasting experience. To date, reassuring preliminary data on this topic were reported in open-label extensions of PLANETRA and PLANETAS RCTs and in ongoing real-life observational studies. These findings, taken all together, significantly affect the landscape of biosimilar regulatory pathways and strongly support CT-P13 introduction as a great opportunity for expanding the accessibility to these very effective and high-cost therapies.

  17. CTP (Cochlin-tomoprotein) detection in the profuse fluid leakage (gusher) from cochleostomy.

    Science.gov (United States)

    Ikezono, Tetsuo; Sugizaki, Kazuki; Shindo, Susumu; Sekiguchi, Satomi; Pawankar, Ruby; Baba, Shunkichi; Yagi, Toshiaki

    2010-08-01

    By testing 125 samples, we confirmed that Cochlin-tomoprotein (CTP) is present in the perilymph, not in cerebrospinal fluid (CSF). Perilymph and CSF exist in two distinct compartments, even in the case of a malformed inner ear with a bony defect in the lamina cribrosa, as described here. Cochleostomy might have suddenly decreased the perilymph pressure, allowing the influx of CSF into the inner ear resulting in profuse fluid leakage, first perilymph then CSF. The first purpose of this study was to further confirm the specificity of the perilymph-specific protein CTP that we reported recently. Secondly, we assessed the nature of the fluid leakage from the cochleostomy using the CTP detection test. A standardized CTP detection test was performed on 65 perilymph and 60 CSF samples. Samples of profuse fluid leakage collected from cochleostomy during cochlear implantation surgery of one patient with branchio-oto-renal (BOR) syndrome were also tested by the CTP detection test. CTP was detected in 60 of 65 perilymph samples but not in any of the CSF samples. The leaked fluid was shown to contain CTP, i.e. perilymph, at the outset, and then the CTP detection signals gradually disappeared as time elapsed.

  18. Identification and Characterization of the Nuclear Isoform of Drosophila melanogaster CTP:Phosphocholine Cytidylyltransferase

    Science.gov (United States)

    CTP:phosphocholine cytidylyltransferase (CCT) catalyzes the conversion of phosphocholine and cytidine 5'-triphosphate (CTP) to CDP-choline for the eventual synthesis of phosphatidylcholine (PC). The enzyme is regulated by reversible association with cellular membranes, with the rate of catalysis in...

  19. Characterisation of representative building typologies for social housing projects in Brazil and its energy performance

    International Nuclear Information System (INIS)

    Triana, Maria Andrea; Lamberts, Roberto; Sassi, Paola

    2015-01-01

    In Brazil the housing deficit is around 5.5 million houses. To address this need, the government created a programme called “My house, My life”. The main subsidies of the programme are for families earning up to three times the minimum wage. In order to formulate strategies for more energy efficiency buildings, it is necessary to understand the thermal and energy performance of what is being built. This article defines representative projects for typologies being built in the Brazilian social housing sector through the analysis of 108 projects considering two groups of income levels and investigates the thermal and energy performance of the representative projects in relation to the Regulation for Energy Efficiency Labelling of Residential Buildings in Brazil for two bioclimatic zones. Five representative building models were defined. Considering the most common features found on the sample, the study suggests the importance of addresing energy efficiency measures on the sector since current building techniques for social housing shows a tendency towards a low performance in relation to the thermal and energy performance criteria of the Energy Labelling especially for lower income projects. This provides a basis for future policy and allows for more in depth studies within the sector. - Highlights: • Characterisation of representative typologies built for social housing in Brazil. • More recurrent building physics characteristics considered. • Energy efficiency and thermal performance of Brazilian social housing analysed. • Regulation for Energy Efficiency Labelling of Residential Buildings in Brazil used for analysis.

  20. CTP synthase forms the cytoophidium in human hepatocellular carcinoma.

    Science.gov (United States)

    Chang, Chia-Chun; Jeng, Yung-Ming; Peng, Min; Keppeke, Gerson Dierley; Sung, Li-Ying; Liu, Ji-Long

    2017-12-15

    CTP synthase (CTPS) can aggregate into an intracellular macrostructure, the cytoophidium, in various organisms including human cells. Previous studies have shown that assembly of human CTPS cytoophidia may be correlated with the cellular metabolic status, and is able to promote the activity of CTPS. A correlation between the cytoophidium and cancer metabolism has been proposed but not yet been revealed. In the current study we provide clear evidence of the presence of CTPS cytoophidia in various human cancers and some non-cancerous tissues. Moreover, among 203 tissue samples of hepatocellular carcinoma, 56 (28%) samples exhibited many cytoophidia, whereas no cytoophidia were detected in adjacent non-cancerous hepatocytes for all samples. Our findings suggest that the CTPS cytoophidium may participate in the adaptive metabolism of human hepatocellular carcinoma. Copyright © 2017. Published by Elsevier Inc.

  1. Exact CTP renormalization group equation for the coarse-grained effective action

    International Nuclear Information System (INIS)

    Dalvit, D.A.; Mazzitelli, F.D.

    1996-01-01

    We consider a scalar field theory in Minkowski spacetime and define a coarse-grained closed time path (CTP) effective action by integrating quantum fluctuations of wavelengths shorter than a critical value. We derive an exact CTP renormalization group equation for the dependence of the effective action on the coarse-graining scale. We solve this equation using a derivative expansion approach. Explicit calculation is performed for the λφ 4 theory. We discuss the relevance of the CTP average action in the study of nonequilibrium aspects of phase transitions in quantum field theory. copyright 1996 The American Physical Society

  2. Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus

    DEFF Research Database (Denmark)

    Lauritsen, Iben; Willemoës, Martin; Jensen, Kaj Frank

    2011-01-01

    CTP synthase catalyzes the last committed step in de novo pyrimidine-nucleotide biosynthesis. Active CTP synthase is a tetrameric enzyme composed of a dimer of dimers. The tetramer is favoured in the presence of the substrate nucleotides ATP and UTP; when saturated with nucleotide, the tetramer...... completely dominates the oligomeric state of the enzyme. Furthermore, phosphorylation has been shown to regulate the oligomeric states of the enzymes from yeast and human. The crystal structure of a dimeric form of CTP synthase from Sulfolobus solfataricus has been determined at 2.5 Å resolution...

  3. The Antimetabolite ara-CTP Blocks Long-Term Memory of Conditioned Taste Aversion

    OpenAIRE

    Wang, Jianpeng; Ren, Keqin; Pérez, Javier; Silva, Alcino J.; Peña de Ortiz, Sandra

    2003-01-01

    We examined the hypothesis that processes related to DNA recombination and repair are involved in learning and memory. Rats received intracerebroventricular (icv) infusions of the antimetabolite 1-beta-D-arabinofuranosylcytosine triphosphate (ara-CTP) or its precursor cytosine arabinoside (ara-C) 30 min prior to conditioned taste aversion (CTA) training. Both ara-CTP and ara-C caused significant impairments in long-term memory (LTM) of CTA. Control experiments indicate that the effect of ara-...

  4. The antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion.

    Science.gov (United States)

    Wang, Jianpeng; Ren, Keqin; Pérez, Javier; Silva, Alcino J; Peña de Ortiz, Sandra

    2003-01-01

    We examined the hypothesis that processes related to DNA recombination and repair are involved in learning and memory. Rats received intracerebroventricular (i.c.v.) infusions of the antimetabolite 1-beta-D-arabinofuranosylcytosine triphosphate (ara-CTP) or its precursor cytosine arabinoside (ara-C) 30 min prior to conditioned taste aversion (CTA) training. Both ara-CTP and ara-C caused significant impairments in long-term memory (LTM) of CTA. Control experiments indicate that the effect of ara-CTP on CTA memory is related to interference with learning. Furthermore, as it was previously demonstrated for the protein synthesis inhibitor anisomycin, ara-CTP had no effect on CTA memory when it was injected 1 h after training. Importantly, although both ara-CTP and anisomycin significantly blocked LTM in the task, short-term memory (STM) measured 1 h after training was not affected by either of the drugs. Finally, ara-CTP had no effect on in vitro transcription, but it did effectively block nonhomologous DNA end joining (NHEJ) activity of brain protein extracts. We suggest that DNA ligase-mediated DNA recombination and repair processes are necessary for the expression of LTM in the brain.

  5. Future Projection of Droughts over South Korea Using Representative Concentration Pathways (RCPs

    Directory of Open Access Journals (Sweden)

    Byung Sik Kim

    2014-01-01

    Full Text Available The Standardized Precipitation Index (SPI, a method widely used to analyze droughts related to climate change, does not consider variables related to temperature and is limited because it cannot consider changes in hydrological balance, such as evapotranspiration from climate change. If we were to consider only the future increase in precipitation from climate change, droughts may decrease. However, because usable water can diminish from an increase in evapotranspiration, it is important to research on projected droughts considering the amount of evapotranspiration along with projecting and evaluating potential droughts considering the impact of climate change. As such, this study evaluated the occurrence of droughts using the Standardized Precipitation Evapotranspiration Index (SPEI as a newly conceptualized drought index that is similar to SPI but includes the temperature variability. We extracted simulated future precipitation and temperature data (2011 - 2099 from the Representative Concentration Pathway (RCP climate change scenario of IPCC AR5 to evaluate the impact of future climate change on the occurrence of droughts of South Korea. We analyzed the ratio of evapotranspiration to precipitation of meteorological observatories nationwide. In addition, we calculated the SPEI related to drought in the process to evaluate the future occurrence of droughts of South Korea. To confirm validity of SPEI results, extreme indices were analyzed. This resulted in the notion that as we go further into the future, the precipitation increases. But because of an increase in evapotranspiration also from a rise in temperature and continued dryness, the severity of droughts is projected to exacerbate.

  6. A review of the literature analyzing benefits and concerns of infliximab biosimilar CT-P13 for the treatment of rheumatologic diseases: focus on interchangeability

    Directory of Open Access Journals (Sweden)

    Becciolini A

    2017-06-01

    Full Text Available Andrea Becciolini,1 Maria Gabriella Raimondo,2 Chiara Crotti,2 Elena Agape,2 Martina Biggioggero,2 Ennio Giulio Favalli1 1Department of Rheumatology, 2Department of Clinical Sciences and Health Community, University of Milan, Division of Rheumatology, Gaetano Pini Institute, Milan, Italy Abstract: The introduction of biological agents drastically changed the treatment paradigm of inflammatory arthritides, ameliorating the natural history of the diseases but concomitantly increasing the drug costs due to the manufacturing process. On this concern, biosimilar drugs may represent a valid option for reducing this elevated cost and increasing the availability of these highly effective treatments. Recently, CT-P13, the first biosimilar of infliximab, has been approved with the same indications established for the reference product (RP, and its daily use is progressively increasing. However, the experience with biosimilar drugs in the field of rheumatology is still limited, raising potential doubts and concerns on their correct management in real-life settings. Comparability analysis between CT-P13 and its RP was evaluated in equivalence randomized controlled trials (RCTs – PLANETRA and PLANETAS – performed on patients with rheumatoid arthritis and axial spondylitis, respectively. CT-P13 and RP showed similar profile in terms of quality, biological activity, safety, immunogenicity, and efficacy. However, the interchangeability between infliximab RP and its biosimilar still represents the most challenging issue because of a lack of a long-lasting experience. To date, reassuring preliminary data on this topic were reported in open-label extensions of PLANETRA and PLANETAS RCTs and in ongoing real-life observational studies. These findings, taken all together, significantly affect the landscape of biosimilar regulatory pathways and strongly support CT-P13 introduction as a great opportunity for expanding the accessibility to these very effective and

  7. Mechanish of dTTP Inhibition of the Bifunctional dCTP Deaminase:dUTPase Encoded by Mycobacterium tuberculosis

    DEFF Research Database (Denmark)

    Helt, Signe Smedegaard; Thymark, Majbritt; Harris, Pernille

    2008-01-01

    Recombinant deoxycytidine triphosphate (dCTP) deaminase from Mycobacterium tuberculosis was produced in Escherichia coli and purified. The enzyme proved to be a bifunctional dCTP deaminase:deoxyuridine triphosphatase. As such, the M. tuberculosis enzyme is the second bifunctional enzyme to be cha......Recombinant deoxycytidine triphosphate (dCTP) deaminase from Mycobacterium tuberculosis was produced in Escherichia coli and purified. The enzyme proved to be a bifunctional dCTP deaminase:deoxyuridine triphosphatase. As such, the M. tuberculosis enzyme is the second bifunctional enzyme...

  8. Revealing, Reducing, and Representing Uncertainties in New Hydrologic Projections for Climate-changed Futures

    Science.gov (United States)

    Arnold, Jeffrey; Clark, Martyn; Gutmann, Ethan; Wood, Andy; Nijssen, Bart; Rasmussen, Roy

    2016-04-01

    The United States Army Corps of Engineers (USACE) has had primary responsibility for multi-purpose water resource operations on most of the major river systems in the U.S. for more than 200 years. In that time, the USACE projects and programs making up those operations have proved mostly robust against the range of natural climate variability encountered over their operating life spans. However, in some watersheds and for some variables, climate change now is known to be shifting the hydroclimatic baseline around which that natural variability occurs and changing the range of that variability as well. This makes historical stationarity an inappropriate basis for assessing continued project operations under climate-changed futures. That means new hydroclimatic projections are required at multiple scales to inform decisions about specific threats and impacts, and for possible adaptation responses to limit water-resource vulnerabilities and enhance operational resilience. However, projections of possible future hydroclimatologies have myriad complex uncertainties that require explicit guidance for interpreting and using them to inform those decisions about climate vulnerabilities and resilience. Moreover, many of these uncertainties overlap and interact. Recent work, for example, has shown the importance of assessing the uncertainties from multiple sources including: global model structure [Meehl et al., 2005; Knutti and Sedlacek, 2013]; internal climate variability [Deser et al., 2012; Kay et al., 2014]; climate downscaling methods [Gutmann et al., 2012; Mearns et al., 2013]; and hydrologic models [Addor et al., 2014; Vano et al., 2014; Mendoza et al., 2015]. Revealing, reducing, and representing these uncertainties is essential for defining the plausible quantitative climate change narratives required to inform water-resource decision-making. And to be useful, such quantitative narratives, or storylines, of climate change threats and hydrologic impacts must sample

  9. [Experience of knowledge translation in the ITSAL (immigration, work and health) research project with representatives of the target population].

    Science.gov (United States)

    Ronda, Elena; López-Jacob, M José; Paredes-Carbonell, Joan J; López, Pilar; Boix, Pere; García, Ana M

    2014-01-01

    This article describes the experience of knowledge translation between researchers of the ITSAL (immigration, work and health) project and representatives of organizations working with immigrants to discuss the results obtained in the project and future research lines. A meeting was held, attended by three researchers and 18 representatives from 11 institutions. Following a presentation of the methodology and results of the project, the participants discussed the results presented and research areas of interest, thus confirming matches between the two sides and obtaining proposals of interest for the ITSAL project. We understand the process described as an approach to social validation of some of the main results of this project. This experience has allowed us to open a channel of communication with the target population of the study, in line with the necessary two-way interaction between researchers and users. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

  10. Evaluation of Representative Smart Grid Investment Grant Project Technologies: Thermal Energy Storage

    Energy Technology Data Exchange (ETDEWEB)

    Tuffner, Francis K.; Bonebrake, Christopher A.

    2012-02-14

    This document is one of a series of reports estimating the benefits of deploying technologies similar to those implemented on the Smart Grid Investment Grant (SGIG) projects. Four technical reports cover the various types of technologies deployed in the SGIG projects, distribution automation, demand response, energy storage, and renewables integration. A fifth report in the series examines the benefits of deploying these technologies on a national level. This technical report examines the impacts of energy storage technologies deployed in the SGIG projects.

  11. Celebrating the Smithsonian Soils Exhibit in the Classroom with the State/Representative Soil Project

    Science.gov (United States)

    Mikhailova, E. A.; Post, C. J.; Koppenheffer, Andrea; Asbill, John

    2009-01-01

    State/representative soil is one of many symbols (e.g., tree, flower, bird, etc.) adopted by citizens to be recognized as an important item to their state. We have developed a set of laboratory exercises, assignments, and exam questions utilizing the state/representative soil that gives college students an opportunity to practice interpretation of…

  12. Evaluation of Representative Smart Grid Investment Grant Project Technologies: Distributed Generation

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Ruchi; Vyakaranam, Bharat GNVSR

    2012-02-14

    This document is one of a series of reports estimating the benefits of deploying technologies similar to those implemented on the Smart Grid Investment Grant (SGIG) projects. Four technical reports cover the various types of technologies deployed in the SGIG projects, distribution automation, demand response, energy storage, and renewables integration. A fifth report in the series examines the benefits of deploying these technologies on a national level. This technical report examines the impacts of addition of renewable resources- solar and wind in the distribution system as deployed in the SGIG projects.

  13. Fiscal years 2007 and 2008 : representative examples of completed RD&T projects and activities

    Science.gov (United States)

    2009-06-01

    The tables in this document correspond to major offices and initiatives at the Federal Highway Administration's Office of Research, Development, and Technology (RD&T), located at the Turner-Fairbank Highway Research Center. The tables provide represe...

  14. Development of oral CTL vaccine using a CTP-integrated Sabin 1 poliovirus-based vector system.

    Science.gov (United States)

    Han, Seung-Soo; Lee, Jinjoo; Jung, Yideul; Kang, Myeong-Ho; Hong, Jung-Hyub; Cha, Min-Suk; Park, Yu-Jin; Lee, Ezra; Yoon, Cheol-Hee; Bae, Yong-Soo

    2015-09-11

    We developed a CTL vaccine vector by modification of the RPS-Vax system, a mucosal vaccine vector derived from a poliovirus Sabin 1 strain, and generated an oral CTL vaccine against HIV-1. A DNA fragment encoding a cytoplasmic transduction peptide (CTP) was integrated into the RPS-Vax system to generate RPS-CTP, a CTL vaccine vector. An HIV-1 p24 cDNA fragment was introduced into the RPS-CTP vector system and a recombinant poliovirus (rec-PV) named vRPS-CTP/p24 was produced. vRPS-CTP/p24 was genetically stable and efficiently induced Th1 immunity and p24-specific CTLs in immunized poliovirus receptor-transgenic (PVR-Tg) mice. In challenge experiments, PVR-Tg mice that were pre-immunized orally with vRPS-CTP/p24 were resistant to challenge with a lethal dose of p24-expressing recombinant vaccinia virus (rMVA-p24). These results suggested that the RPS-CTP vector system had potential for developing oral CTL vaccines against infectious diseases. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Cytoplasmic transduction peptide (CTP): New approach for the delivery of biomolecules into cytoplasm in vitro and in vivo

    International Nuclear Information System (INIS)

    Kim, Daeyou; Jeon, Choonju; Kim, Jeong-Hwan; Kim, Mi-Seon; Yoon, Cheol-Hee; Choi, In-Soo; Kim, Sung-Hoon; Bae, Yong-Soo

    2006-01-01

    The protein transduction domain (PTD) of HIV-1 TAT has been extensively documented with regard to its membrane transduction potential, as well as its efficient delivery of biomolecules in vivo. However, the majority of PTD and PTD-conjugated molecules translocate to the nucleus rather than to the cytoplasm after transduction, due to the functional nuclear localization sequence (NLS). Here, we report a cytoplasmic transduction peptide (CTP), which was deliberately designed to ensure the efficient cytoplasmic delivery of the CTP-fused biomolecules. In comparison with PTD, CTP and its fusion partners exhibited a clear preference for cytoplasmic localization, and also markedly enhanced membrane transduction potential. Unlike the mechanism underlying PTD-mediated transduction, CTP-mediated transduction occurs independently of the lipid raft-dependent macropinocytosis pathway. The CTP-conjugated Smac/DIABLO peptide (Smac-CTP) was also shown to be much more efficient than Smac-PTD in the blockage of the antiapoptotic properties of XIAP, suggesting that cytoplasmic functional molecules can be more efficiently targeted by CTP-mediated delivery. In in vivo trafficking studies, CTP-fused β-gal exhibited unique organ tropisms to the liver and lymph nodes when systemically injected into mice, whereas PTD-β-gal exhibited no such tropisms. Taken together, our findings implicate CTP as a novel delivery peptide appropriate for (i) molecular targeting to cytoplasmic compartments in vitro, (ii) the development of class I-associated CTL vaccines, and (iii) special drug delivery in vivo, without causing any untoward effects on nuclear genetic material

  16. A scientific update on biosimilar infliximab (CT-P13) in rheumatic diseases.

    Science.gov (United States)

    Taylor, Peter

    2015-01-01

    The development of biologic drugs has undoubtedly enhanced the spectrum of treatments available for immune-mediated inflammatory rheumatic diseases such as rheumatoid arthritis. However, despite their clear clinical benifits, use of biologics is often hindered by their high costs. The manufacture and subsequent approval of more cost-effective 'biosimilar' versions of these drugs may address this issue and improve patient access. CT-P13 (Remsima(®), Inflectra(®)), a biosimilar of infliximab (Remicade(®)), has shown comparable efficacy, safety and pharmacokinetics to its originator drug in clinical studies. The articles in this supplement present a scientific update on the development and use of biosimilars in rheumatic disorders, with specific focus on CT-P13. The information discussed highlights the predicted positive clinical and economic impact of biosimilars on the management of rheumatic diseases.

  17. Monitoring ATLAS L1 CTP data from P-BEAST

    CERN Document Server

    Roggel, Jens

    2017-01-01

    The ATLAS Level-1 Central Trigger Processor combines information from the calori-meters and the muon detectors and takes a decision to accept an event based on a list of selection criteria (trigger items). Busy signals from the detectors and generated dead time by the Central Trigger Processor prevents the buffers to become full. The visualisation of this data is useful to check the functionality of the system. My project during the CERN summer student programme was to develop an application, which produces plots of relevant Central Trigger Processor data and presents the results in an appropriate format for experts and users.

  18. Cochlin-tomoprotein (CTP) detection test identified perilymph leakage preoperatively in revision stapes surgery.

    Science.gov (United States)

    Kataoka, Yuko; Ikezono, Tetsuo; Fukushima, Kunihiro; Yuen, Koji; Maeda, Yukihide; Sugaya, Akiko; Nishizaki, Kazunori

    2013-08-01

    Perilymphatic fistula (PLF) is defined as an abnormal leakage between perilymph from the labyrinth to the middle ear. Symptoms include hearing loss, tinnitus, and vertigo. The standard mode of PLF detection is intraoperative visualization of perilymph leakage and fistula, which ostensibly confirms the existence of PLF. Other possible methods of diagnosis include confirmation of pneumolabyrinth via diagnostic imaging. Recently, a cochlin-tomoprotein (CTP) detection test has been developed that allows definitive diagnosis of PLF-related hearing loss. We report the case of a 45-year-old man who presented with right-sided tinnitus, hearing loss, and dizziness 30 years after stapes surgery. Middle ear lavage was performed after myringotomy. A preoperative diagnosis of PLF was reached using the CTP detection test. Intraoperative observations included a necrotic long process of the incus, displaced wire piston, and fibrous tissue in the oval window. Perilymph leakage was not evident. The oval window was closed with fascia, and vertigo disappeared within 2 weeks postoperatively. When PLF is suspected after stapes surgery, the CTP detection test can be a useful, highly sensitive, and less invasive method for preoperative diagnosis. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  19. La-CTP: Loop-Aware Routing for Energy-Harvesting Wireless Sensor Networks.

    Science.gov (United States)

    Sun, Guodong; Shang, Xinna; Zuo, Yan

    2018-02-02

    In emerging energy-harvesting wireless sensor networks (EH-WSN), the sensor nodes can harvest environmental energy to drive their operation, releasing the user's burden in terms of frequent battery replacement, and even enabling perpetual sensing systems. In EH-WSN applications, usually, the node in energy-harvesting or recharging state has to stop working until it completes the energy replenishment. However, such temporary departures of recharging nodes severely impact the packet routing, and one immediate result is the routing loop problem. Controlling loops in connectivity-intermittent EH-WSN in an efficient way is a big challenge in practice, and so far, users still lack of effective and practicable routing protocols with loop handling. Based on the Collection Tree Protocol (CTP) widely used in traditional wireless sensor networks, this paper proposes a loop-aware routing protocol for real-world EH-WSNs, called La-CTP, which involves a new parent updating metric and a proactive, adaptive beaconing scheme to effectively suppress the occurrence of loops and unlock unavoidable loops, respectively. We constructed a 100-node testbed to evaluate La-CTP, and the experimental results showed its efficacy and efficiency.

  20. Constructing and Representing: a New Project for 3d Surveying of Yazilikaya - HATTUŠA

    Science.gov (United States)

    Repola, L.; Marazzi, M.; Tilia, S.

    2017-05-01

    Within the cooperation project between the University Suor Orsola Benincasa of Naples and the archaeological mission in Hattuša of the German Archaeological Institute of Istanbul, directed by Andreas Schachner, in agreement with the Turkish Ministry of Culture and Tourism, the workgroup of the University of Naples, has carried out, in September 2015, a first survey campaign of the whole rocky site of Yazılıkaya. The experimentation has been finalized at constructing a global 3D territorial and monumental model of the site, capable that is, through the application of differing scanning procedures, according to the different components (topography, rocky complex, the cultural spaces therein, complex of sculptural reliefs, inscriptions accompanying the divine representations), of virtually reproducing in detail, for safegaurd, exhibition and study purposes (in particular from an epigraphical and historic-artistic point of view) all the aspects characterizing the artefact and not completely visible to the naked eye today.

  1. Inverse regulation of two classic Hippo pathway target genes in Drosophila by the dimerization hub protein Ctp.

    Science.gov (United States)

    Barron, Daniel A; Moberg, Kenneth

    2016-03-14

    The LC8 family of small ~8 kD proteins are highly conserved and interact with multiple protein partners in eukaryotic cells. LC8-binding modulates target protein activity, often through induced dimerization via LC8:LC8 homodimers. Although many LC8-interactors have roles in signaling cascades, LC8's role in developing epithelia is poorly understood. Using the Drosophila wing as a developmental model, we find that the LC8 family member Cut up (Ctp) is primarily required to promote epithelial growth, which correlates with effects on the pro-growth factor dMyc and two genes, diap1 and bantam, that are classic targets of the Hippo pathway coactivator Yorkie. Genetic tests confirm that Ctp supports Yorkie-driven tissue overgrowth and indicate that Ctp acts through Yorkie to control bantam (ban) and diap1 transcription. Quite unexpectedly however, Ctp loss has inverse effects on ban and diap1: it elevates ban expression but reduces diap1 expression. In both cases these transcriptional changes map to small segments of these promoters that recruit Yorkie. Although LC8 complexes with Yap1, a Yorkie homolog, in human cells, an orthologous interaction was not detected in Drosophila cells. Collectively these findings reveal that that Drosophila Ctp is a required regulator of Yorkie-target genes in vivo and suggest that Ctp may interact with a Hippo pathway protein(s) to exert inverse transcriptional effects on Yorkie-target genes.

  2. Ceramic Technology Project data base: September 1992 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1993-06-01

    Data presented in this report represent an intense effort to improve processing methods, testing methods, and general mechanical properties (rupture modulus, tensile, creep, stress-rupture, dynamic and cyclic fatigue, fracture toughness) of candidate ceramics for use in advanced heat engines. This work was performed by many facilities and represents only a small part of the data generated by the Ceramic Technology Project (CTP) since 1986. Materials discussed include GTE PY6, GN-10, NT-154, NT-164, SN-260, SN-251, SN-252, AY6, silicon nitride combined with rare-earth oxides, Y-TZP, ZTA, NC-433, NT-230, Hexoloy SA, MgO-PSZ-to-MgO-PSZ joints, MgO-PSZ-to-cast iron, and a few whisker/fiber-reinforced ceramics. Information in this report was taken from the project`s semiannual and bimonthly progress reports and from final reports summarizing the results of individual studies. Test results are presented in tabular form and in graphs. All data, including test rig descriptions and material characterizations, are stored in the CTP data base and are available to all project participants on request. The objective of this report is to make available the test results from these studies but not to draw conclusions from those data.

  3. Efficacy and safety of switching from reference infliximab to CT-P13 compared with maintenance of CT-P13 in ankylosing spondylitis: 102-week data from the PLANETAS extension study.

    Science.gov (United States)

    Park, Won; Yoo, Dae Hyun; Miranda, Pedro; Brzosko, Marek; Wiland, Piotr; Gutierrez-Ureña, Sergio; Mikazane, Helena; Lee, Yeon-Ah; Smiyan, Svitlana; Lim, Mie-Jin; Kadinov, Vladimir; Abud-Mendoza, Carlos; Kim, HoUng; Lee, Sang Joon; Bae, YunJu; Kim, SuYeon; Braun, Jürgen

    2017-02-01

    To investigate the efficacy and safety of switching from infliximab reference product (RP) to its biosimilar or maintaining biosimilar treatment in patients with ankylosing spondylitis (AS). This open-label extension study recruited patients with AS who completed a 54-week, randomised controlled study comparing CT-P13 with RP (PLANETAS). CT-P13 (5 mg/kg) was administered intravenously every 8 weeks from week 62 to week 102. Efficacy end points included the proportion of patients achieving Assessment of SpondyloArthritis international Society (ASAS)20. Antidrug antibodies (ADAs) were measured using an electrochemiluminescent method. Data were analysed for patients treated with CT-P13 in the main PLANETAS study and the extension (maintenance group) and those who were switched to CT-P13 during the extension study (switch group). Overall, 174 (82.9%) of 210 patients who completed the first 54 weeks of PLANETAS and agreed to participate in the extension were enrolled. Among these, 88 were maintained on CT-P13 and 86 were switched to CT-P13 from RP. In these maintenance and switch groups, respectively, ASAS20 response rates at week 102 were 80.7% and 76.9%. ASAS40 and ASAS partial remission were also similar between groups. ADA positivity rates were comparable (week 102: 23.3% vs 27.4%). Adverse events led to treatment discontinuation during the extension study in 3 (3.3%) and 4 (4.8%) patients, respectively. This is the first study to show that switching from RP to its biosimilar CT-P13 is possible without negative effects on safety or efficacy in patients with AS. In the maintenance group, CT-P13 was effective and well tolerated over 2 years of treatment. NCT01571206; Results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  4. Allosteric regulation of the GTP activated and CTP inhibited uracil phosphoribosyltransferase from the thermophilic archaeon Sulfolobus solfataricus

    DEFF Research Database (Denmark)

    Jensen, Kaj Frank; Arent, Susan; Larsen, Sine

    2005-01-01

    The upp gene, encoding uracil phosphoribosyltransferase (UPRTase) from the thermoacidophilic archaeon Sulfolobus solfataricus, was cloned and expressed in Escherichia coli. The enzyme was purified to homogeneity. It behaved as a tetramer in solution and showed optimal activity at pH 5.5 when...... assayed at 60 °C. Enzyme activity was strongly stimulated by GTP and inhibited by CTP. GTP caused an approximately 20-fold increase in the turnover number kcat and raised the Km values for 5-phosphoribosyl-1-diphosphate (PRPP) and uracil by two- and >10-fold, respectively. The inhibition by CTP...... was complex as it depended on the presence of the reaction product UMP. Neither CTP nor UMP were strong inhibitors of the enzyme, but when present in combination their inhibition was extremely powerful. Ligand binding analyses showed that GTP and PRPP bind cooperatively to the enzyme and that the inhibitors...

  5. Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells.

    Directory of Open Access Journals (Sweden)

    Wendy C Carcamo

    Full Text Available Cytoplasmic filamentous rods and rings (RR structures were identified using human autoantibodies as probes. In the present study, the formation of these conserved structures in mammalian cells and functions linked to these structures were examined.Distinct cytoplasmic rods (∼3-10 µm in length and rings (∼2-5 µm in diameter in HEp-2 cells were initially observed in immunofluorescence using human autoantibodies. Co-localization studies revealed that, although RR had filament-like features, they were not enriched in actin, tubulin, or vimentin, and not associated with centrosomes or other known cytoplasmic structures. Further independent studies revealed that two key enzymes in the nucleotide synthetic pathway cytidine triphosphate synthase 1 (CTPS1 and inosine monophosphate dehydrogenase 2 (IMPDH2 were highly enriched in RR. CTPS1 enzyme inhibitors 6-diazo-5-oxo-L-norleucine and Acivicin as well as the IMPDH2 inhibitor Ribavirin exhibited dose-dependent induction of RR in >95% of cells in all cancer cell lines tested as well as mouse primary cells. RR formation by lower concentration of Ribavirin was enhanced in IMPDH2-knockdown HeLa cells whereas it was inhibited in GFP-IMPDH2 overexpressed HeLa cells. Interestingly, RR were detected readily in untreated mouse embryonic stem cells (>95%; upon retinoic acid differentiation, RR disassembled in these cells but reformed when treated with Acivicin.RR formation represented response to disturbances in the CTP or GTP synthetic pathways in cancer cell lines and mouse primary cells and RR are the convergence physical structures in these pathways. The availability of specific markers for these conserved structures and the ability to induce formation in vitro will allow further investigations in structure and function of RR in many biological systems in health and diseases.

  6. CTP:phosphocholine cytidylyltransferase and protein kinase C recognize different physical features of membranes: differential responses to an oxidized phosphatidylcholine

    NARCIS (Netherlands)

    Drobnies, A.E.; Davies, S.M.A.; Kraayenhof, R.; Epand, R.F.; Epand, R.M.; Cornell, R.B.

    2002-01-01

    Protein kinase C (PKC) and CTP:phosphocholine cytidylyltransferase (CT) are two examples of enzymes that are regulated by reversible binding to membranes, and this binding is influenced by membrane physical properties. CT activation by oxidized phosphatidylcholines was recently demonstrated and was

  7. Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2

    Directory of Open Access Journals (Sweden)

    Lin Zhu

    2008-01-01

    Full Text Available Metabolic pulse-chase experiments demonstrated that 25-hydroxycholesterol (25-OH, the endogenous activator of the liver X receptor (LXR, significantly reduced the biosynthesis of phosphatidylethanolamine via CDP-ethanolamine (Kennedy pathway at the step catalyzed by CTP: phosphoethanolamine cytidylyltransferase (Pcyt2. In the mouse embryonic fibroblasts C3H10T1/2, the LXR synthetic agonist TO901317 lowered Pcyt2 promoter-luciferase activity in a concentration-dependent manner. Furthermore, 25-OH and TO901317 reduced mouse Pcyt2 mRNA and protein levels by 35–60%. The inhibitory effects of oxysterols and TO901317 on the Pcyt2 promoter function, mRNA and protein expression were conserved in the human breast cancer cells MCF-7. These studies identify the Pcyt2 gene as a novel target whereby LXR agonists may indirectly modulate inflammatory responses and atherosclerosis.

  8. Evaluation of the Cross-reactivity of Antidrug Antibodies to CT-P13 and Infliximab Reference Product (Remicade): An Analysis Using Immunoassays Tagged with Both Agents.

    Science.gov (United States)

    Reinisch, Walter; Jahnsen, Jørgen; Schreiber, Stefan; Danese, Silvio; Panés, Julián; Balsa, Alejandro; Park, Won; Kim, JiSoo; Lee, Jee Un; Yoo, Dae Hyun

    2017-06-01

    During two pivotal clinical trials of the infliximab biosimilar CT-P13 (PLANETAS and PLANETRA), antidrug antibodies (ADAs) and neutralising antibodies (NAbs) were detected in the sera of patients treated with CT-P13 and the reference product (RP; Remicade). The aim was to assess the comparability of Remicade- and CT-P13-tagged immunoassays for the detection of ADAs and NAbs using data from these trials, in order to determine the cross-reactivity of CT-P13 and RP ADAs. Sera from patients with rheumatoid arthritis and ankylosing spondylitis were analysed using an electrochemiluminescence (ECL) bridging assay or Gyros immunoassay, tagged with Remicade or CT-P13 at screening, weeks 14, 30 and 54, and the end of study visit. NAb titre was compared at screening and weeks 14 and 30. The proportion of cross-reactive samples was determined and an inter-rater agreement analysis performed to assess the concordance of results between assays. In PLANETAS, 93.1% (94/101) of RP ADA-positive samples and 93.0% (93/100) of RP NAb-positive samples cross-reacted with CT-P13; 99.0% (103/104) of CT-P13 ADA-positive and 98.0% (98/100) of CT-P13 NAb-positive samples cross-reacted with the RP. In PLANETRA, 94.7% (426/450) of RP ADA-positive samples and 94.3% (415/440) of RP NAb-positive samples cross-reacted with CT-P13, and 96.6% (458/474) of CT-P13 ADA-positive and 96.4% (452/469) of CT-P13 NAb-positive samples cross-reacted with the RP. In both studies, there was strong agreement in outcome between assays at all post-screening time points (PLANETAS: Cohen's κ 0.89-0.98 for ADA, 0.86-0.98 for NAb; PLANETRA: 0.92-0.94 for both ADA and NAb, all p PLANETAS: Spearman's ρ 0.73 and 0.74, respectively; PLANETRA: 0.61 and 0.72, respectively; all p < 0.001). This study has demonstrated that ADAs and NAbs against CT-P13 and RP are cross-reactive, indicating that CT-P13 and RP share immunodominant epitopes.

  9. Representing time

    Directory of Open Access Journals (Sweden)

    Luca Poncellini

    2010-06-01

    Full Text Available The analysis of natural phenomena applied to architectural planning and design is facing the most fascinating and elusive of the four dimensions through which man attempts to define life within the universe: time. We all know what time is, said St. Augustine, but nobody knows how to describe it. Within architectural projects and representations, time rarely appears in explicit form. This paper presents the results of a research conducted by students of NABA and of the Polytechnic of Milan with the purpose of representing time considered as a key element within architectural projects. Student investigated new approaches and methodologies to represent time using the two-dimensional support of a sheet of paper.

  10. Infliximab Biosimilar (CT-P13; Infliximab-dyyb): A Review in Autoimmune Inflammatory Diseases.

    Science.gov (United States)

    Blair, Hannah A; Deeks, Emma D

    2016-10-01

    Infliximab biosimilar (CT-P13/infliximab-dyyb; Remsima ® , Inflectra ® ) is approved in several countries for use in all indications for which reference infliximab (Remicade ® ) is approved, including rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis, psoriasis, Crohn's disease, and ulcerative colitis. Clinical data contributing to the EU approval of infliximab biosimilar were obtained from two pivotal double-blind clinical trials in patients with AS (PLANETAS) or RA (PLANETRA). Infliximab biosimilar demonstrated equivalence to reference infliximab in terms of its pharmacokinetic profile in patients with AS, patients with RA, and in healthy volunteers, and in terms of its efficacy in patients with RA. Clinical response rates in patients with RA or AS were maintained over the longer term (up to 102 weeks). In addition, the efficacy of infliximab biosimilar in patients with RA or Crohn's disease and ulcerative colitis [i.e. inflammatory bowel disease (IBD)] has been demonstrated in the real-world setting. Infliximab biosimilar was generally well tolerated, with a tolerability profile similar to that of reference infliximab. Switching from reference infliximab to infliximab biosimilar had no detrimental effect on efficacy, safety, or immunogenicity compared with continuous infliximab biosimilar therapy, according to the extensions of PLANETAS and PLANETRA, and real-world data in IBD. Current evidence therefore suggests that infliximab biosimilar is a useful alternative to reference infliximab in patients with autoimmune inflammatory diseases.

  11. Usefulness of three-dimensional CT pancreatography (3D-CTP) after the balloon-ERP for pancreatic diseases

    International Nuclear Information System (INIS)

    Ueki, Toshiharu; Oishi, Yayoi; Sakaguchi, Seigo; Sakurai, Toshihiro; Yao, Tsuneyoshi; Ichimaru, Yoshihiko; Koga, Yuki; Ikeda, Seiyo

    1998-01-01

    The clinical usefulness of 3D-CTP combined with the balloon-ERP and helical-CT was discussed. Authors diagnosed 42 patients with pancreatic diseases, including 5 of pancreatic carcinoma, 3 of serous cystadenoma, 6 of muciparous pancreatic cyst, 28 of chronic pancreatitis (including 8 cases of complicated pseudocyst). The images could reconstruct three-dimensionally the tapering constriction in the main pancreatic duct for all 5 cases of pancreatic carcinoma, the exclusion in the main pancreatic duct for 3 cases of serous cystadenoma and 1 case of muciparous pancreatic cyst, the parietal irregularity for 14 cases and the smooth constriction for 9 cases in main pancreatic duct of chronic pancreatitis, the morphology of the cyst and the spatial relationship between the cyst and the pancreatic duct in 5 of 6 cases of muciparous pancreatic cyst and 7 of 8 cases of complicated pseudocyst. Furthermore, the 3D-CTP could demonstrate the branched pancreatic duct at the constriction site which was not detected by the balloon-ERP in 2 cases of chronic pancreatitis with the constriction at the main pancreatic duct, and the joining manner of cyst to the pancreatic duct which was indistinct by the balloon-ERP in 6 cases of pancreatic cyst. These results show that 3D-CTP is useful for the qualitative diagnosis and applicable for the understanding of pancreatic diseases and for the simulation of surgery. (K.H.)

  12. Progress in biosimilar monoclonal antibody development: the infliximab biosimilar CT-P13 in the treatment of rheumatic diseases.

    Science.gov (United States)

    Braun, Jürgen; Kudrin, Alex

    2015-01-01

    Biosimilars are biologic medical products whose active drug substance is made by a living organism or derived from it. The term is used to describe a subsequent version of an innovator biopharmaceutical product aiming at approval following patent expiry on the reference product. Biosimilars of monoclonal need to demonstrate similar but not identical quality of nonclinical and clinical attributes. Not all data of the originator product need to be recapitulated, as large numbers of patient-years of exposure data are already available. Thus, biosimilar development is largely based on the safety profiles of the originator product. The evaluation of biosimilarity includes immunogenicity attributed risks. CT-P13 (Remsima™/Inflectra™, Celltrion/Hospira), a biosimilar of the innovator drug infliximab (INF), was the first approved complex biosimilar monoclonal antibody in the EU, within the framework of WHO, EMA and US FDA biosimilar guidelines. CT-P13 has shown analytical and nonclinical features highly similar to INF including pharmacokinetics, efficacy, safety and immunogenicity profiles in ankylosing spondylitis and rheumatoid arthritis. The objective of this article is to highlight the recent biosimilar development and to review the results from the studies PLANETRA and PLANETAS, which have supported the approval of CT-P13 for several indications.

  13. A projection-free method for representing plane-wave DFT results in an atom-centered basis

    International Nuclear Information System (INIS)

    Dunnington, Benjamin D.; Schmidt, J. R.

    2015-01-01

    Plane wave density functional theory (DFT) is a powerful tool for gaining accurate, atomic level insight into bulk and surface structures. Yet, the delocalized nature of the plane wave basis set hinders the application of many powerful post-computation analysis approaches, many of which rely on localized atom-centered basis sets. Traditionally, this gap has been bridged via projection-based techniques from a plane wave to atom-centered basis. We instead propose an alternative projection-free approach utilizing direct calculation of matrix elements of the converged plane wave DFT Hamiltonian in an atom-centered basis. This projection-free approach yields a number of compelling advantages, including strict orthonormality of the resulting bands without artificial band mixing and access to the Hamiltonian matrix elements, while faithfully preserving the underlying DFT band structure. The resulting atomic orbital representation of the Kohn-Sham wavefunction and Hamiltonian provides a gateway to a wide variety of analysis approaches. We demonstrate the utility of the approach for a diverse set of chemical systems and example analysis approaches

  14. Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme

    DEFF Research Database (Denmark)

    Johansson, Eva; Thymark, Majbritt; Bynck, Julie H

    2007-01-01

    -maximal activity and the cooperativity of dCTP saturation. Likewise, increasing concentrations of dCTP increase the cooperativity of dTTP inhibition. Previous structural studies showed that the complexes of inactive mutant protein, E138A, with dUTP or dCTP bound, and wild-type enzyme with dUTP bound were all...... highly similar and characterized by having an ordered C-terminal. When comparing with a new structure in which dTTP is bound to the active site of E138A, the region between Val120 and His125 was found to be in a new conformation. This and the previous conformation were mutually exclusive within...

  15. Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product.

    Science.gov (United States)

    Dunne, Matthew; Leicht, Stefan; Krichel, Boris; Mertens, Haydyn D T; Thompson, Andrew; Krijgsveld, Jeroen; Svergun, Dmitri I; Gómez-Torres, Natalia; Garde, Sonia; Uetrecht, Charlotte; Narbad, Arjan; Mayer, Melinda J; Meijers, Rob

    2016-03-04

    Bacteriophages produce endolysins, which lyse the bacterial host cell to release newly produced virions. The timing of lysis is regulated and is thought to involve the activation of a molecular switch. We present a crystal structure of the activated endolysin CTP1L that targets Clostridium tyrobutyricum, consisting of a complex between the full-length protein and an N-terminally truncated C-terminal cell wall binding domain (CBD). The truncated CBD is produced through an internal translation start site within the endolysin gene. Mutants affecting the internal translation site change the oligomeric state of the endolysin and reduce lytic activity. The activity can be modulated by reconstitution of the full-length endolysin-CBD complex with free CBD. The same oligomerization mechanism applies to the CD27L endolysin that targets Clostridium difficile and the CS74L endolysin that targets Clostridium sporogenes. When the CTP1L endolysin gene is introduced into the commensal bacterium Lactococcus lactis, the truncated CBD is also produced, showing that the alternative start codon can be used in other bacterial species. The identification of a translational switch affecting oligomerization presented here has implications for the design of effective endolysins for the treatment of bacterial infections. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  16. A nationwide non-medical switch from originator infliximab to biosimilar CT-P13 in 802 patients with inflammatory arthritis

    DEFF Research Database (Denmark)

    Glintborg, Bente; Sørensen, Inge Juul; Loft, Anne Gitte

    2017-01-01

    Objectives According to guidelines, a nationwide non-medical switch from originator (INX, Remicade) to biosimilar infliximab (Remsima, CT-P13) was conducted in Danish patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (AxSpA). We investigated disease...

  17. Uracil phosphoribosyltransferase from the extreme thermoacidophilic archaebacterium Sulfolobus shibatae is an allosteric enzyme, activated by GTP and inhibited by CTP

    DEFF Research Database (Denmark)

    Linde, Lise; Jensen, Kaj Frank

    1996-01-01

    Uracil phosphoribosyltransferase, which catalyses the formation of UMP and pyrophosphate from uracil and 5-phosphoribosyl a-1-pyrophosphate (PRPP), was partly purified from the extreme thermophilic archaebacterium Sulfolobus shibatae. The enzyme required divalent metal ions for activity...... and it showed the highest activity at pH 6.4. The specific activity of the enzyme was 50-times higher at 95°C than at 37°C, but the functional half-life was short at 95°C. The activity of uracil phosphoribosyltransferase was strongly activated by GTP, which increased Vmax of the reaction by approximately 20......-fold without much effect on Km for the substrates. The concentration of GTP required for half-maximal activation was about 80 µM. CTP was a strong inhibitor and acted by raising the concentration of GTP needed for half-maximal activation of the enzyme. We conclude that uracil phosphoribosyltransferase...

  18. PVC esaslı CTP kesme atığı dolgulu malzemelerin termal özelliklerinin incelenmesi

    Directory of Open Access Journals (Sweden)

    Arzu Özüyağlı

    2016-08-01

    Full Text Available Bu çalışmada, PVC üretiminde kullanılan CaCO3 dolgu malzemesi yerine, sanayi atığı kullanılması sonucu termal özelliklerdeki değişim araştırılmıştır. Kullanılan sanayi atığı CTP boru üretiminden sulu kesim sırasında çıkmakta ve SiO2, cam elyaf ve polyester reçine içermektedir. Sulu çamur halinde filtre presten çıkan atık fabrikadan alındıktan sonra kurutma ve eleme işlemleri uygulanarak toz formuna getirilmiştir. Numuneler PVC, CTP atık tozu ve prosese yardımcı maddeler mikserde karıştırılarak ekstrüzyon yöntemi ile profil şeklinde üretilmiştir. Atık toz PVC’ye oranla ağırlıkça %5-%70 oranlarında dolgu malzemesi olarak kullanılmıştır. Kalsit (CaCO3 katkılı ve katkısız PVC numuneleri de benzer proses parametreleri kullanılarak üretilmiştir. Üretilen numuneler, seramik krozeler kullanılarak DTA-TG analizleri yapılmıştır.

  19. Cooperative binding of the bisubstrate analog N-(phosphonacetyl)-L-aspartate to aspartate transcarbamoylase and the heterotropic effects of ATP and CTP

    International Nuclear Information System (INIS)

    Newell, J.O.; Markby, D.W.; Schachman, H.K.

    1989-01-01

    Most investigations of the allosteric properties of the regulatory enzyme aspartate transcarbamoylase (ATCase) from Escherichia coli are based on the sigmoidal dependence of enzyme activity on substrate concentration and the effects of the inhibitor, CTP, and the activator, ATP, on the saturation curves. Interpretations of these effects in terms of molecular models are complicated by the inability to distinguish between changes in substrate binding and catalytic turnover accompanying the allosteric transition. In an effort to eliminate this ambiguity, the binding of the 3H-labeled bisubstrate analog N-(phosphonacetyl)-L-aspartate (PALA) to aspartate transcarbamoylase in the absence and presence of the allosteric effectors ATP and CTP has been measured directly by equilibrium dialysis at pH 7 in phosphate buffer. PALA binds with marked cooperativity to the holoenzyme with an average dissociation constant of 110 nM. ATP and CTP alter both the average affinity of ATCase for PALA and the degree of cooperativity in the binding process in a manner analogous to their effects on the kinetic properties of the enzyme; the average dissociation constant of PALA decreases to 65 nM in the presence of ATP and increases to 266 nM in the presence of CTP while the Hill coefficient, which is 1.95 in the absence of effectors, becomes 1.35 and 2.27 in the presence of ATP and CTP, respectively. The dissociation constant of PALA from the catalytic subunit is 95 nM. Interpretation of these results in terms of a thermodynamic scheme linking PALA binding to the assembly of ATCase from catalytic and regulatory subunits demonstrates that saturation of the enzyme with PALA shifts the equilibrium between holoenzyme and subunits slightly toward dissociation

  20. Representing Development

    DEFF Research Database (Denmark)

    Representing Development presents the different social representations that have formed the idea of development in Western thinking over the past three centuries. Offering an acute perspective on the current state of developmental science and providing constructive insights into future pathways, ...

  1. A workforce survey of Australian osteopathy: analysis of a nationally-representative sample of osteopaths from the Osteopathy Research and Innovation Network (ORION) project.

    Science.gov (United States)

    Adams, Jon; Sibbritt, David; Steel, Amie; Peng, Wenbo

    2018-05-10

    Limited information is available regarding the profile and clinical practice characteristics of the osteopathy workforce in Australia. This paper reports such information by analysing data from a nationally-representative sample of Australian osteopaths. Data was obtained from a workforce survey of Australian osteopathy, investigating the characteristics of the practitioner, their practice, clinical management features and perceptions regarding research. The survey questionnaire was distributed to all registered osteopaths across Australia in 2016 as part of the Osteopathy Research and Innovation Network (ORION) project. A total of 992 Australian osteopaths participated in this study representing a response rate of 49.1%. The average age of the participants was 38.0 years with 58.1% being female and the majority holding a Bachelor or higher degree qualification related to the osteopathy professional. Approximately 80.0% of the osteopaths were practicing in an urban area, with most osteopaths working in multi-practitioner locations, having referral relationships with a range of health care practitioners, managing patients a number of musculoskeletal disorders, and providing multi-model treatment options. A total of 3.9 million patients were estimated to consult with osteopaths every year and an average of approximate 3.0 million hours were spent delivering osteopathy services per year. Further research is required to provide rich, in-depth examination regarding a range of osteopathy workforce issues which will help ensure safe, effective patient care to all receiving and providing treatments as part of the broader Australian health system.

  2. Systematic design for trait introgression projects.

    Science.gov (United States)

    Cameron, John N; Han, Ye; Wang, Lizhi; Beavis, William D

    2017-10-01

    Using an Operations Research approach, we demonstrate design of optimal trait introgression projects with respect to competing objectives. We demonstrate an innovative approach for designing Trait Introgression (TI) projects based on optimization principles from Operations Research. If the designs of TI projects are based on clear and measurable objectives, they can be translated into mathematical models with decision variables and constraints that can be translated into Pareto optimality plots associated with any arbitrary selection strategy. The Pareto plots can be used to make rational decisions concerning the trade-offs between maximizing the probability of success while minimizing costs and time. The systematic rigor associated with a cost, time and probability of success (CTP) framework is well suited to designing TI projects that require dynamic decision making. The CTP framework also revealed that previously identified 'best' strategies can be improved to be at least twice as effective without increasing time or expenses.

  3. Representing dispositions

    Directory of Open Access Journals (Sweden)

    Röhl Johannes

    2011-08-01

    Full Text Available Abstract Dispositions and tendencies feature significantly in the biomedical domain and therefore in representations of knowledge of that domain. They are not only important for specific applications like an infectious disease ontology, but also as part of a general strategy for modelling knowledge about molecular interactions. But the task of representing dispositions in some formal ontological systems is fraught with several problems, which are partly due to the fact that Description Logics can only deal well with binary relations. The paper will discuss some of the results of the philosophical debate about dispositions, in order to see whether the formal relations needed to represent dispositions can be broken down to binary relations. Finally, we will discuss problems arising from the possibility of the absence of realizations, of multi-track or multi-trigger dispositions and offer suggestions on how to deal with them.

  4. 30 March 2009 - Representatives of the Danish Council for Independent Research Natural Sciences visiting the LHC tunnel at Point 1 with Collaboration Spokesperson F. Gianotti, Former Spokesperson P. Jenni and Transition Radiation Tracker Project Leader C. Rembser.

    CERN Document Server

    Maximilien Brice

    2009-01-01

    30 March 2009 - Representatives of the Danish Council for Independent Research Natural Sciences visiting the LHC tunnel at Point 1 with Collaboration Spokesperson F. Gianotti, Former Spokesperson P. Jenni and Transition Radiation Tracker Project Leader C. Rembser.

  5. 28 May 2010 - Representatives of the Netherlands School of Public Administration guided in the ATLAS visitor centre by ATLAS Collaboration Member and NIKHEF G. Bobbink and ATLAS Magnet Project Leader H.ten Kate.

    CERN Document Server

    Maximilien Brice

    2010-01-01

    28 May 2010 - Representatives of the Netherlands School of Public Administration guided in the ATLAS visitor centre by ATLAS Collaboration Member and NIKHEF G. Bobbink and ATLAS Magnet Project Leader H.ten Kate.

  6. A web-based institutional DICOM distribution system with the integration of the Clinical Trial Processor (CTP).

    Science.gov (United States)

    Aryanto, K Y E; Broekema, A; Langenhuysen, R G A; Oudkerk, M; van Ooijen, P M A

    2015-05-01

    To develop and test a fast and easy rule-based web-environment with optional de-identification of imaging data to facilitate data distribution within a hospital environment. A web interface was built using Hypertext Preprocessor (PHP), an open source scripting language for web development, and Java with SQL Server to handle the database. The system allows for the selection of patient data and for de-identifying these when necessary. Using the services provided by the RSNA Clinical Trial Processor (CTP), the selected images were pushed to the appropriate services using a protocol based on the module created for the associated task. Five pipelines, each performing a different task, were set up in the server. In a 75 month period, more than 2,000,000 images are transferred and de-identified in a proper manner while 20,000,000 images are moved from one node to another without de-identification. While maintaining a high level of security and stability, the proposed system is easy to setup, it integrate well with our clinical and research practice and it provides a fast and accurate vendor-neutral process of transferring, de-identifying, and storing DICOM images. Its ability to run different de-identification processes in parallel pipelines is a major advantage in both clinical and research setting.

  7. CAUDAL MEDULLARY PATHWAYS TO LUMBOSACRAL MOTONEURONAL CELL GROUPS IN THE CAT - EVIDENCE FOR DIRECT PROJECTIONS POSSIBLY REPRESENTING THE FINAL COMMON PATHWAY FOR LORDOSIS

    NARCIS (Netherlands)

    VANDERHORST, VGJM; HOLSTEGE, G

    1995-01-01

    The nucleus retroambiguus (NRA) projects to distinct brainstem and cervical and thoracic cord motoneuronal cell groups. The present paper describes NRA projections to distinct motoneuronal cell groups in the lumbar enlargement. Lumbosacral injections of wheat germ agglutinin-horseradish peroxidase

  8. Caudal Medullary Pathways To Lumbosacral Motoneuronal Cell Groups In The Cat; Evidence For Direct Projections Possibly Representing The Final Common Pathway For Lordosis.

    NARCIS (Netherlands)

    VanderHorst, Veronique G.J.M.; Holstege, Gert

    1995-01-01

    The nucleus retroambiguus (NRA) projects to distinct brainstem and cervical and thoracic cord motoneuronal cell groups. The present paper describes NRA projections to distinct motoneuronal cell groups in the lumbar enlargement. Lumbosacral injections of wheat germ agglutinin-horseradish peroxidase

  9. Efficacy and Safety of the Biosimilar Infliximab CT-P13 Treatment in Inflammatory Bowel Diseases: A Prospective, Multicentre, Nationwide Cohort.

    Science.gov (United States)

    Gecse, Krisztina B; Lovász, Barbara D; Farkas, Klaudia; Banai, János; Bene, László; Gasztonyi, Beáta; Golovics, Petra Anna; Kristóf, Tünde; Lakatos, László; Csontos, Ágnes Anna; Juhász, Márk; Nagy, Ferenc; Palatka, Károly; Papp, Mária; Patai, Árpád; Lakner, Lilla; Salamon, Ágnes; Szamosi, Tamás; Szepes, Zoltán; Tóth, Gábor T; Vincze, Áron; Szalay, Balázs; Molnár, Tamás; Lakatos, Péter L

    2016-02-01

    Biosimilar infliximab CT-P13 is approved for all indications of the originator product in Europe. Prospective data on its efficacy, safety, and immunogenicity in inflammatory bowel diseases are lacking. A prospective, nationwide, multicentre, observational cohort was designed to examine the efficacy, safety, and immunogenicity of CT-P13 infliximab biosimilar in the induction treatment of Crohn's disease [CD] and ulcerative colitis [UC]. Demographic data were collected and a harmonised monitoring strategy was applied. Early clinical remission, response, and early biochemical response were evaluated at Week 14, steroid-free clinical remission was evaluated at Week 30. Therapeutic drug level was monitored using a conventional enzyme-linked immunosorbent assay. In all, 210 consecutive inflammatory bowel disease [126 CD and 84 UC] patients were included in the present cohort. At Week 14, 81.4% of CD and 77.6% of UC patients showed clinical response and 53.6% of CD and 58.6% of UC patients were in clinical remission. Clinical remission rates at Week 14 were significantly higher in CD and UC patients who were infliximab naïve, compared with those with previous exposure to the originator compound [p < 0.05]. Until Week 30, adverse events were experienced in 17.1% of all patients. Infusion reactions and infectious adverse events occurred in 6.6% and 5.7% of all patients, respectively. This prospective multicentre cohort shows that CT-P13 is safe and effective in the induction of clinical remission and response in both CD and UC. Patients with previous infliximab exposure exhibited decreased response rates and were more likely to develop allergic reactions. Copyright © 2015 European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  10. Ceramic Technology Project database: September 1993 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1994-01-01

    Data presented in this report represent an intense effort to improve processing methods, testing methods, and general mechanical properties of candidate ceramics for use in advanced heat engines. Materials discussed include GN-10, GS-44, GTE PY6, NT-154, NT-164, sintered-reaction-bonded silicon nitrides, silicon nitride combined with rare-earth oxides, NT-230, Hexoloy SX-G1, Dow Corning`s {beta}-Si{sub 3}N{sub 4}, and a few whisker-reinforced ceramic composites. Information in this report was taken from the project`s semiannual and bimonthly progress reports and from final reports summarizing the results of individual studies. Test results are presented in tabular form and in graphs. All data, including test rig descriptions and material characterizations, are stored in the CTP database and are available to all project participants on request. Objective of this report is to make available the test results from these studies but not to draw conclusions from those data.

  11. Engaging Diverse Students in Statistical Inquiry: A Comparison of Learning Experiences and Outcomes of Under-Represented and Non-Underrepresented Students Enrolled in a Multidisciplinary Project-Based Statistics Course

    Science.gov (United States)

    Dierker, Lisa; Alexander, Jalen; Cooper, Jennifer L.; Selya, Arielle; Rose, Jennifer; Dasgupta, Nilanjana

    2016-01-01

    Introductory statistics needs innovative, evidence-based teaching practices that support and engage diverse students. To evaluate the success of a multidisciplinary, project-based course, we compared experiences of under-represented (URM) and non-underrepresented students in 4 years of the course. While URM students considered the material more…

  12. Comparable long-term efficacy, as assessed by patient-reported outcomes, safety and pharmacokinetics, of CT-P13 and reference infliximab in patients with ankylosing spondylitis: 54-week results from the randomized, parallel-group PLANETAS study.

    Science.gov (United States)

    Park, Won; Yoo, Dae Hyun; Jaworski, Janusz; Brzezicki, Jan; Gnylorybov, Andriy; Kadinov, Vladimir; Sariego, Irmgadt Goecke; Abud-Mendoza, Carlos; Escalante, William Jose Otero; Kang, Seong Wook; Andersone, Daina; Blanco, Francisco; Hong, Seung Suh; Lee, Sun Hee; Braun, Jürgen

    2016-01-20

    CT-P13 (Remsima®, Inflectra®) is a biosimilar of the infliximab reference product (RP; Remicade®) and is approved in Europe and elsewhere, mostly for the same indications as RP. The aim of this study was to compare the 54-week efficacy, immunogenicity, pharmacokinetics (PK) and safety of CT-P13 with RP in patients with ankylosing spondylitis (AS), with a focus on patient-reported outcomes (PROs). This was a multinational, double-blind, parallel-group study in patients with active AS. Participants were randomized (1:1) to receive CT-P13 (5 mg/kg) or RP (5 mg/kg) at weeks 0, 2, 6 and then every 8 weeks up to week 54. To assess responses, standardized assessment tools were used with an intention-to-treat analysis of observed data. Anti-drug antibodies (ADAs), PK parameters, and safety outcomes were also assessed. Of 250 randomized patients (n = 125 per group), 210 (84.0 %) completed 54 weeks of treatment, with similar completion rates between groups. At week 54, Assessment of Spondylo Arthritis international Society (ASAS)20 response, ASAS40 response and ASAS partial remission were comparable between treatment groups. Changes from baseline in PROs such as mean Bath Ankylosing Spondylitis Disease Activity Index (BASDAI; CT-P13 -3.1 versus RP -2.8), Bath Ankylosing Spondylitis Functional Index (BASFI; -2.9 versus -2.7), and Short Form Health Survey (SF-36) scores (9.26 versus 10.13 for physical component summary; 7.30 versus 6.54 for mental component summary) were similar between treatment groups. At 54 weeks, 19.5 % and 23.0 % of patients receiving CT-P13 and RP, respectively, had ADAs. All observed PK parameters of CT-P13 and RP, including maximum and minimum serum concentrations, were similar through 54 weeks. The influence of ADAs on PK was similar in the two treatment groups. Most adverse events were mild or moderate in severity. There was no notable difference between treatment groups in the incidence of adverse events, serious adverse events

  13. A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in patients with ankylosing spondylitis: the PLANETAS study.

    Science.gov (United States)

    Park, Won; Hrycaj, Pawel; Jeka, Slawomir; Kovalenko, Volodymyr; Lysenko, Grygorii; Miranda, Pedro; Mikazane, Helena; Gutierrez-Ureña, Sergio; Lim, MieJin; Lee, Yeon-Ah; Lee, Sang Joon; Kim, HoUng; Yoo, Dae Hyun; Braun, Jürgen

    2013-10-01

    To compare the pharmacokinetics (PK), safety and efficacy of innovator infliximab (INX) and CT-P13, a biosimilar to INX, in patients with active ankylosing spondylitis (AS). Phase 1 randomised, double-blind, multicentre, multinational, parallel-group study. Patients were randomised to receive 5 mg/kg of CT-P13 (n=125) or INX (n=125). Primary endpoints were area under the concentration-time curve (AUC) at steady state and observed maximum steady state serum concentration (Cmax,ss) between weeks 22 and 30. Additional PK, efficacy endpoints, including 20% and 40% improvement response according to Assessment in Ankylosing Spondylitis International Working Group criteria (ASAS20 and ASAS40), and safety outcomes were also assessed. Geometric mean AUC was 32 765.8 μgh/ml for CT-P13 and 31 359.3 μgh/ml for INX. Geometric mean Cmax,ss was 147.0 μg/ml for CT-P13 and 144.8 μg/ml for INX. The ratio of geometric means was 104.5% (90% CI 94% to 116%) for AUC and 101.5% (90% CI 95% to 109%) for Cmax,ss. ASAS20 and ASAS40 responses at week 30 were 70.5% and 51.8% for CT-P13 and 72.4% and 47.4% for INX, respectively. In the CT-P13 and INX groups more than one adverse event occurred in 64.8% and 63.9% of patients, infusion reactions occurred in 3.9% and 4.9%, active tuberculosis occurred in 1.6% and 0.8%, and 27.4% and 22.5% of patients tested positive for anti-drug antibodies, respectively. The PK profiles of CT-P13 and INX were equivalent in patients with active AS. CT-P13 was well tolerated, with an efficacy and safety profile comparable to that of INX up to week 30.

  14. Characterizing the context of sedentary lifestyles in a representative sample of adults: a cross-sectional study from the physical activity measurement study project.

    Science.gov (United States)

    Kim, Youngwon; Welk, Gregory J

    2015-12-09

    Research has clearly demonstrated that excess time spent on sedentary behavior (SB) increases health risks in the population. However, the lack of information on the context of SB in the population prevents a detailed understanding of sedentary lifestyles. The purpose of this study was to characterize the context of SB in a representative sample of adults and to examine differences across various socio-demographic indicators. A diverse sample of 1442 adults (ages 20-71 year) completed an interviewer-administered 24-h activity recall to provide detailed information about the time, type and location of the previous day's activities. All reported activities were matched with MET scores from the Compendium of Physical Activity but only SB (i.e., METS Work: 27.5%, Community: 24.8%, Home/Indoor: 20.5%, Home/Outdoor: 15.8%, and Transportation: 11.3%). Patterns of SB allocations varied considerably across different socio-demographic indicators indicating the extreme variability in SB in the population. The findings provide unique insights about the context of SB at the population level, and can serve as a guide for developing intervention/policy studies to reduce sedentary time and minimize disparities in SB.

  15. Large-scale monitoring of effects of clothianidin dressed oilseed rape seeds on pollinating insects in Northern Germany: implementation of the monitoring project and its representativeness.

    Science.gov (United States)

    Heimbach, Fred; Russ, Anja; Schimmer, Maren; Born, Katrin

    2016-11-01

    Monitoring studies at the landscape level are complex, expensive and difficult to conduct. Many aspects have to be considered to avoid confounding effects which is probably the reason why they are not regularly performed in the context of risk assessments of plant protection products to pollinating insects. However, if conducted appropriately their contribution is most valuable. In this paper we identify the requirements of a large-scale monitoring study for the assessment of side-effects of clothianidin seed-treated winter oilseed rape on three species of pollinating insects (Apis mellifera, Bombus terrestris and Osmia bicornis) and present how these requirements were implemented. Two circular study sites were delineated next to each other in northeast Germany and comprised almost 65 km 2 each. At the reference site, study fields were drilled with clothianidin-free OSR seeds while at the test site the oilseed rape seeds contained a coating with 10 g clothianidin and 2 g beta-cyfluthrin per kg seeds (Elado®). The comparison of environmental conditions at the study sites indicated that they are as similar as possible in terms of climate, soil, land use, history and current practice of agriculture as well as in availability of oilseed rape and non-crop bee forage. Accordingly, local environmental conditions were considered not to have had any confounding effect on the results of the monitoring of the bee species. Furthermore, the study area was found to be representative for other oilseed rape cultivation regions in Europe.

  16. Scale-up and large-scale production of Tetraselmis sp. CTP4 (Chlorophyta) for CO2 mitigation: from an agar plate to 100-m3 industrial photobioreactors.

    Science.gov (United States)

    Pereira, Hugo; Páramo, Jaime; Silva, Joana; Marques, Ana; Barros, Ana; Maurício, Dinis; Santos, Tamára; Schulze, Peter; Barros, Raúl; Gouveia, Luísa; Barreira, Luísa; Varela, João

    2018-03-23

    Industrial production of novel microalgal isolates is key to improving the current portfolio of available strains that are able to grow in large-scale production systems for different biotechnological applications, including carbon mitigation. In this context, Tetraselmis sp. CTP4 was successfully scaled up from an agar plate to 35- and 100-m 3 industrial scale tubular photobioreactors (PBR). Growth was performed semi-continuously for 60 days in the autumn-winter season (17 th October - 14 th December). Optimisation of tubular PBR operations showed that improved productivities were obtained at a culture velocity of 0.65-1.35 m s -1 and a pH set-point for CO 2 injection of 8.0. Highest volumetric (0.08 ± 0.01 g L -1 d -1 ) and areal (20.3 ± 3.2 g m -2 d -1 ) biomass productivities were attained in the 100-m 3 PBR compared to those of the 35-m 3 PBR (0.05 ± 0.02 g L -1 d -1 and 13.5 ± 4.3 g m -2 d -1 , respectively). Lipid contents were similar in both PBRs (9-10% of ash free dry weight). CO 2 sequestration was followed in the 100-m 3 PBR, revealing a mean CO 2 mitigation efficiency of 65% and a biomass to carbon ratio of 1.80. Tetraselmis sp. CTP4 is thus a robust candidate for industrial-scale production with promising biomass productivities and photosynthetic efficiencies up to 3.5% of total solar irradiance.

  17. Projectables

    DEFF Research Database (Denmark)

    Rasmussen, Troels A.; Merritt, Timothy R.

    2017-01-01

    CNC cutting machines have become essential tools for designers and architects enabling rapid prototyping, model-building and production of high quality components. Designers often cut from new materials, discarding the irregularly shaped remains. We introduce ProjecTables, a visual augmented...... reality system for interactive packing of model parts onto sheet materials. ProjecTables enables designers to (re)use scrap materials for CNC cutting that would have been previously thrown away, at the same time supporting aesthetic choices related to wood grain, avoiding surface blemishes, and other...... relevant material properties. We conducted evaluations of ProjecTables with design students from Aarhus School of Architecture, demonstrating that participants could quickly and easily place and orient model parts reducing material waste. Contextual interviews and ideation sessions led to a deeper...

  18. Budget impact analysis of biosimilar infliximab (CT-P13) for the treatment of rheumatoid arthritis in six Central and Eastern European countries.

    Science.gov (United States)

    Brodszky, Valentin; Baji, Petra; Balogh, Orsolya; Péntek, Márta

    2014-05-01

    The first biosimilar monoclonal antibody (infliximab, CT-P13) was registered by the European Medicines Agency in 2013 for the treatment of several inflammatory conditions including rheumatoid arthritis (RA). Biosimilar infliximab is first being marketed in the Central and Eastern European countries. This paper presents the estimated budget impact of the introduction of biosimilar infliximab in RA over a 3-year time period in six selected countries, namely Bulgaria, the Czech Republic, Hungary, Poland, Romania and Slovakia. A prevalence-based model was constructed for budget impact analysis. Two scenarios were compared to the reference scenario (RSc) where no biosimilar infliximab is available: biosimilar scenario 1 (BSc1), where interchanging the originator infliximab with biosimilar infliximab is disallowed, and only patients who start new biological therapy are allowed to use biosimilar infliximab; as well as biosimilar scenario 2 (BSc2), where interchanging the originator infliximab with biosimilar infliximab is allowed, and 80% of patients treated with originator infliximab are interchanged to biosimilar infliximab. Compared to the RSc, the net savings are estimated to be €15.3 or €20.8 M in BSc1 and BSc2, respectively, over the 3 years. If budget savings were spent on reimbursement of additional biosimilar infliximab treatment, approximately 1,200 or 1,800 more patients could be treated in the six countries within 3 years in the two biosimilar scenarios, respectively. The actual saving is most sensitive to the assumption of the acquisition cost of the biosimilar drug and to the initial number of patients treated with biological therapy. The study focused on one indication (RA) and demonstrated that the introduction of biosimilar infliximab can lead to substantial budget savings in health care budgets. Further savings are expected for other indications where biosimilar medicines are implemented.

  19. Determination of the anomeric specificity of the Escherichia coli CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase by 13C NMR spectroscopy

    International Nuclear Information System (INIS)

    Kohlbrenner, W.E.; Fesik, S.W.

    1985-01-01

    [99%, 1- 13 C]- and [90%, 2- 13 C]3-deoxy-D-manno-octulosonic acid (KDO) were prepared enzymatically and used to determine the anomeric specificity of the CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyl transferase (CMP-KDO synthetase) by 13 C NMR spectroscopy. Addition of CMP-KDO synthetase to reaction mixtures containing either 1- 13 C- or 2- 13 C-labeled KDO resulted in rapid CMP-KDO formation which was accompanied by a substantial decrease in the 13 C-enriched resonances of the beta-pyranose form of KDO relative to the resonances of other KDO species in solution, demonstrating that the beta-pyranose is the preferred substrate. Concomitant with the production of CMP-KDO was the appearance of peaks at 174.3 and 101.4 ppm when [1- 13 C]- and [2- 13 C]KDO, respectively, were used as substrates. The correspondence of these resonances to the enriched carbons in CMP-KDO was confirmed by the expected 3-bond (3JP,C-1 = 6.9 Hz) and 2-bond coupling (2JP,C-2 = 8.3 Hz) between the labeled carbons and the ketosidically linked phosphoryl group. A large coupling (3J = 5.7 Hz) was observed in proton-coupled spectra of CMP-[1- 13 C]KDO between carbon 1 and the axial proton at carbon 3 of KDO. The magnitude of this coupling constant supports a diaxial relationship between these two groups and, along with chemical shift data, indicates that KDO retains the beta-configuration when linked in CMP-KDO

  20. Representative of local committee

    International Nuclear Information System (INIS)

    Barcelo, C.

    2007-01-01

    Carlos Barcelo, spoke about the involvement of local companies in the dismantling project. Local companies realised that they could not undertake the whole project, and informed ENRESA of the tasks in which they would be able to co-operate. On the whole, during the course of the 5-year project the local and regional firms were given more work than they had originally expected. Mr. Barcelo praised the good partnership that evolved between the local firms and the implementer. (author)

  1. Simulation and Evaluation of CTP and Secure-CTP Protocols

    Directory of Open Access Journals (Sweden)

    P. Pecho

    2010-04-01

    Full Text Available The paper discusses characteristics and qualities of two routing protocols – Collection Tree Protocol and its secure modification. The original protocol, as well as other protocols for wireless sensors, solves only problems of ra- dio communication and limited resources. Our design of the secure protocol tries to solve also the essential security ob- jectives. For the evaluation of properties of our protocol in large networks, a TOSSIM simulator was used. Our effort was to show the influence of the modification of the routing protocol to its behavior and quality of routing trees. We have proved that adding security into protocol design does not necessarily mean higher demands for data transfer, power consumption or worse protocol efficiency. In the paper, we manifest that security in the protocol may be achieved with low cost and may offer similar performance as the original protocol.

  2. Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2′-deoxyguanosine by Human DNA Polymerase η*

    Science.gov (United States)

    Patra, Amitraj; Zhang, Qianqian; Guengerich, F. Peter; Egli, Martin

    2016-01-01

    O6-Methyl-2′-deoxyguanosine (O6-MeG) is a ubiquitous DNA lesion, formed not only by xenobiotic carcinogens but also by the endogenous methylating agent S-adenosylmethionine. It can introduce mutations during DNA replication, with different DNA polymerases displaying different ratios of correct or incorrect incorporation opposite this nucleoside. Of the “translesion” Y-family human DNA polymerases (hpols), hpol η is most efficient in incorporating equal numbers of correct and incorrect C and T bases. However, the mechanistic basis for this specific yet indiscriminate activity is not known. To explore this question, we report biochemical and structural analysis of the catalytic core of hpol η. Activity assays showed the truncated form displayed similar misincorporation properties as the full-length enzyme, incorporating C and T equally and extending from both. X-ray crystal structures of both dC and dT paired with O6-MeG were solved in both insertion and extension modes. The structures revealed a Watson-Crick-like pairing between O6-MeG and 2"-deoxythymidine-5"-[(α, β)-imido]triphosphate (approximating dT) at both the insertion and extension stages with formation of two H-bonds. Conversely, both the structures with O6- MeG opposite dCTP and dC display sheared configuration of base pairs but to different degrees, with formation of two bifurcated H-bonds and two single H-bonds in the structures trapped in the insertion and extension states, respectively. The structural data are consistent with the observed tendency of hpol η to insert both dC and dT opposite the O6-MeG lesion with similar efficiencies. Comparison of the hpol η active site configurations with either O6-MeG:dC or O6-MeG:dT bound compared with the corresponding situations in structures of complexes of Sulfolobus solfataricus Dpo4, a bypass pol that favors C relative to T by a factor of ∼4, helps rationalize the more error-prone synthesis opposite the lesion by hpol η. PMID:27694439

  3. Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN, Sae2 (Ctp1, and Mre11-nuclease.

    Directory of Open Access Journals (Sweden)

    James W Westmoreland

    2013-03-01

    Full Text Available Resection is an early step in homology-directed recombinational repair (HDRR of DNA double-strand breaks (DSBs. Resection enables strand invasion as well as reannealing following DNA synthesis across a DSB to assure efficient HDRR. While resection of only one end could result in genome instability, it has not been feasible to address events at both ends of a DSB, or to distinguish 1- versus 2-end resections at random, radiation-induced "dirty" DSBs or even enzyme-induced "clean" DSBs. Previously, we quantitatively addressed resection and the role of Mre11/Rad50/Xrs2 complex (MRX at random DSBs in circular chromosomes within budding yeast based on reduced pulsed-field gel electrophoretic mobility ("PFGE-shift". Here, we extend PFGE analysis to a second dimension and demonstrate unique patterns associated with 0-, 1-, and 2-end resections at DSBs, providing opportunities to examine coincidence of resection. In G2-arrested WT, Δrad51 and Δrad52 cells deficient in late stages of HDRR, resection occurs at both ends of γ-DSBs. However, for radiation-induced and I-SceI-induced DSBs, 1-end resections predominate in MRX (MRN null mutants with or without Ku70. Surprisingly, Sae2 (Ctp1/CtIP and Mre11 nuclease-deficient mutants have similar responses, although there is less impact on repair. Thus, we provide direct molecular characterization of coincident resection at random, radiation-induced DSBs and show that rapid and coincident initiation of resection at γ-DSBs requires MRX, Sae2 protein, and Mre11 nuclease. Structural features of MRX complex are consistent with coincident resection being due to an ability to interact with both DSB ends to directly coordinate resection. Interestingly, coincident resection at clean I-SceI-induced breaks is much less dependent on Mre11 nuclease or Sae2, contrary to a strong dependence on MRX complex, suggesting different roles for these functions at "dirty" and clean DSB ends. These approaches apply to resection at

  4. List of Accredited Representatives

    Data.gov (United States)

    Department of Veterans Affairs — VA accreditation is for the sole purpose of providing representation services to claimants before VA and does not imply that a representative is qualified to provide...

  5. Representing vision and blindness.

    Science.gov (United States)

    Ray, Patrick L; Cox, Alexander P; Jensen, Mark; Allen, Travis; Duncan, William; Diehl, Alexander D

    2016-01-01

    There have been relatively few attempts to represent vision or blindness ontologically. This is unsurprising as the related phenomena of sight and blindness are difficult to represent ontologically for a variety of reasons. Blindness has escaped ontological capture at least in part because: blindness or the employment of the term 'blindness' seems to vary from context to context, blindness can present in a myriad of types and degrees, and there is no precedent for representing complex phenomena such as blindness. We explore current attempts to represent vision or blindness, and show how these attempts fail at representing subtypes of blindness (viz., color blindness, flash blindness, and inattentional blindness). We examine the results found through a review of current attempts and identify where they have failed. By analyzing our test cases of different types of blindness along with the strengths and weaknesses of previous attempts, we have identified the general features of blindness and vision. We propose an ontological solution to represent vision and blindness, which capitalizes on resources afforded to one who utilizes the Basic Formal Ontology as an upper-level ontology. The solution we propose here involves specifying the trigger conditions of a disposition as well as the processes that realize that disposition. Once these are specified we can characterize vision as a function that is realized by certain (in this case) biological processes under a range of triggering conditions. When the range of conditions under which the processes can be realized are reduced beyond a certain threshold, we are able to say that blindness is present. We characterize vision as a function that is realized as a seeing process and blindness as a reduction in the conditions under which the sight function is realized. This solution is desirable because it leverages current features of a major upper-level ontology, accurately captures the phenomenon of blindness, and can be

  6. Ceramics Technology Project database: September 1991 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-06-01

    The piston ring-cylinder liner area of the internal combustion engine must withstand very-high-temperature gradients, highly-corrosive environments, and constant friction. Improving the efficiency in the engine requires ring and cylinder liner materials that can survive this abusive environment and lubricants that resist decomposition at elevated temperatures. Wear and friction tests have been done on many material combinations in environments similar to actual use to find the right materials for the situation. This report covers tribology information produced from 1986 through July 1991 by Battelle columbus Laboratories, Caterpillar Inc., and Cummins Engine Company, Inc. for the Ceramic Technology Project (CTP). All data in this report were taken from the project`s semiannual and bimonthly progress reports and cover base materials, coatings, and lubricants. The data, including test rig descriptions and material characterizations, are stored in the CTP database and are available to all project participants on request. Objective of this report is to make available the test results from these studies, but not to draw conclusions from these data.

  7. Bonneville Power Administration: financial fallout from termination of WPPSS nuclear projects 4 and 5. Oversight hearings before the Subcommittee on Mining, Forest Management, and Bonneville Power Administration of the Committee on Interior and Insular Affairs, House of Representatives, Ninety-Eighth Congress, First Session, February 14 and 15, 1983

    International Nuclear Information System (INIS)

    Anon.

    1983-01-01

    Peter T. Johnson, Administrator of the Bonneville Power Administration, and a representative of the Washington Public Power Supply System (WPPSS) described the financial situation resulting from the cancellations and cost overruns of WPPSS nuclear projects that have left the area with an unacceptable debt. Four panels representing area utilities and electric cooperatives described their financial positions on the second day of hearings. Two appendices with additional material from Bonneville, WPPSS, the Department of the Interior, and others follow the testimony

  8. Representing Color Ensembles.

    Science.gov (United States)

    Chetverikov, Andrey; Campana, Gianluca; Kristjánsson, Árni

    2017-10-01

    Colors are rarely uniform, yet little is known about how people represent color distributions. We introduce a new method for studying color ensembles based on intertrial learning in visual search. Participants looked for an oddly colored diamond among diamonds with colors taken from either uniform or Gaussian color distributions. On test trials, the targets had various distances in feature space from the mean of the preceding distractor color distribution. Targets on test trials therefore served as probes into probabilistic representations of distractor colors. Test-trial response times revealed a striking similarity between the physical distribution of colors and their internal representations. The results demonstrate that the visual system represents color ensembles in a more detailed way than previously thought, coding not only mean and variance but, most surprisingly, the actual shape (uniform or Gaussian) of the distribution of colors in the environment.

  9. OSMOSE experiment representativity studies.

    Energy Technology Data Exchange (ETDEWEB)

    Aliberti, G.; Klann, R.; Nuclear Engineering Division

    2007-10-10

    The OSMOSE program aims at improving the neutronic predictions of advanced nuclear fuels through measurements in the MINERVE facility at the CEA-Cadarache (France) on samples containing the following separated actinides: Th-232, U-233, U-234, U-235, U-236, U-238, Np-237, Pu-238, Pu-239, Pu-240, Pu-241, Pu-242, Am-241, Am-243, Cm-244 and Cm-245. The goal of the experimental measurements is to produce a database of reactivity-worth measurements in different neutron spectra for the separated heavy nuclides. This database can then be used as a benchmark for integral reactivity-worth measurements to verify and validate reactor analysis codes and integral cross-section values for the isotopes tested. In particular, the OSMOSE experimental program will produce very accurate sample reactivity-worth measurements for a series of actinides in various spectra, from very thermalized to very fast. The objective of the analytical program is to make use of the experimental data to establish deficiencies in the basic nuclear data libraries, identify their origins, and provide guidelines for nuclear data improvements in coordination with international programs. To achieve the proposed goals, seven different neutron spectra can be created in the MINERVE facility: UO2 dissolved in water (representative of over-moderated LWR systems), UO2 matrix in water (representative of LWRs), a mixed oxide fuel matrix, two thermal spectra containing large epithermal components (representative of under-moderated reactors), a moderated fast spectrum (representative of fast reactors which have some slowing down in moderators such as lead-bismuth or sodium), and a very hard spectrum (representative of fast reactors with little moderation from reactor coolant). The different spectra are achieved by changing the experimental lattice within the MINERVE reactor. The experimental lattice is the replaceable central part of MINERVE, which establishes the spectrum at the sample location. This configuration

  10. Representing distance, consuming distance

    DEFF Research Database (Denmark)

    Larsen, Gunvor Riber

    Title: Representing Distance, Consuming Distance Abstract: Distance is a condition for corporeal and virtual mobilities, for desired and actual travel, but yet it has received relatively little attention as a theoretical entity in its own right. Understandings of and assumptions about distance...... are being consumed in the contemporary society, in the same way as places, media, cultures and status are being consumed (Urry 1995, Featherstone 2007). An exploration of distance and its representations through contemporary consumption theory could expose what role distance plays in forming...

  11. Regulation and construction of nuclear powerplants: South Texas Nuclear Project. Hearing before the Subcommittee on Oversight and Investigations of the Committee on Interstate and Foreign Commerce, House of Representatives, Ninety-sixth Congress, Second Session

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    On September 23, 1980, the Subcommittee of Oversight and Investigation held a congressional hearing to discuss the regulation and construction of the South Texas Nuclear Power Plant project. Discussion included recommendations to prevent problems, like the problem encountered at Three Mile Island, from occurring during construction and operation. The chairman of the Nuclear Regulatory Commission discussed the procedure for inspection and regulation process. One power plant at the South Texas project experienced significant problems because of an inadequate quality assurance and quality control program. These difficulties caused delay in construction, increased cost, and raised questions of safety. The problems encountered at Three Mile Island and at the first plant of the South Texas project provided the reasons for this congressional hearing

  12. Representative of the Media

    International Nuclear Information System (INIS)

    Domenech, F.

    2007-01-01

    Francesc Domenech recalled that the Vandellos-I accident created a very difficult situation for the nuclear industry. During the crisis the nuclear sector decided not to participate in any media activities. Finally, the industry realised that not being open only exacerbated the credibility crisis. The closure of the Vandellos -I power plant decreased the stress and offered an opportunity for the nuclear sector to change its attitude and public relations. In Mr. Domenech's view the Vandellos-I decommissioning project is a technical challenge undertaken by society. ENRESA made great efforts to rebuild mutual trust between the nuclear industry and the media. For the first time, journalists were provided with fluid data, some of them very complex, which the media had to render more understandable for the public. Finally, Mr. Domenech observed that nowadays it is the regulator which most needs to gain credibility. (author)

  13. Representing AIDS in Comics.

    Science.gov (United States)

    Czerwiec, M K

    2018-02-01

    Matthew P. McAllister wrote: "Comic books can and have contributed positively to the discourse about AIDS: images that encourage true education, understanding and compassion can help cope with a biomedical condition which has more than a biomedical relevance" [1]. With this in mind, I combined a 23-narrator oral history and my personal memoir about an inpatient Chicago AIDS hospital unit in my book, Taking Turns: Stories from HIV/AIDS Care Unit 371. In doing so, I built upon the existing rich history of HIV/AIDS in comics, which this article will briefly describe. Although not a comprehensive review of the intersection of AIDS and comics, the book is a tour through influences that proved useful to me. In addition, in making my book, I faced a distinct ethical issue with regard to representing patient experiences with HIV/AIDS, and I describe here how I addressed it. © 2018 American Medical Association. All Rights Reserved.

  14. Representative of the municipality

    International Nuclear Information System (INIS)

    Castellnou Barcelo, J.

    2007-01-01

    Full text of publication follows. The decommissioning of the Vandellos-I nuclear power plant was a big challenge for the host community of Vandellos i l'Hospitalet de l'Infant and the close-by region. Closing down of the facility resulted in a rise of unemployment and a decrease of municipal income. The public was concerned with three issues: safety, transparency and information about the decommissioning, and economic future. Therefore, from the very beginning, municipal governments entered into negotiations with ENRESA on socio-economic benefits, including local employment in dismantling activities, and other types of financial and non-financial compensation. The ADE business association, i.e. a network of business organisations was created that guided the allotment of work to local firms. To satisfy public demand, local municipalities focused on the triad of safety, dialogue and local development, considered the three 'pillars of trust'. A Municipal Monitoring Commission was created, made up of representatives of affected municipalities, the regional government, the ADE business association, trade unions, the local university, the NPP management and ENRESA to monitor the dismantling process and regularly inform the local public. Items that were handled by this Commission included: - Work process monitoring. - Workers. - Materials Control. - Conventional and radioactive or contaminated waste management. - Emanation waste management (liquid and gas) - Safety (training and accidents). - Surveillance (radiological and environmental: dust, noise). - Effects. - Fulfillment of agreed conditions. A number of communication tools and channels were used, e.g., public information meetings, an information centre, the municipal magazine, the municipal radio station, and meetings with representatives of the local press. Particularly innovative was the idea to ask academics from the University of Tarragona to help with 'translating' technical information into language that could

  15. Integration tests of prototype LVL1 calorimeter trigger CP/JEP ROD and LVL2 trigger Region-of-Interest Builder. Also visible in the photo are two further racks containing the demonstrator prototypes of the LVL1 CTP and the MUCTPI.

    CERN Multimedia

    Gee, N

    2001-01-01

    Integration tests of prototype LVL1 calorimeter trigger CP/JEP ROD and LVL2 trigger Region-of-Interest Builder. Also visible in the photo are two further racks containing the demonstrator prototypes of the LVL1 CTP and the MUCTPI.

  16. How Y-Family DNA polymerase IV is more accurate than Dpo4 at dCTP insertion opposite an N2-dG adduct of benzo[a]pyrene.

    Science.gov (United States)

    Sholder, Gabriel; Creech, Amanda; Loechler, Edward L

    2015-11-01

    To bypass DNA damage, cells have Y-Family DNA polymerases (DNAPs). One Y-Family-class includes DNAP κ and DNAP IV, which accurately insert dCTP opposite N(2)-dG adducts, including from the carcinogen benzo[a]pyrene (BP). Another class includes DNAP η and DNAP V, which insert accurately opposite UV-damage, but inaccurately opposite BP-N(2)-dG. To investigate structural differences between Y-Family-classes, regions are swapped between DNAP IV (a κ/IV-class-member) and Dpo4 (a η/V-class-member); the kinetic consequences are evaluated via primer-extension studies with a BP-N(2)-dG-containing template. Four key structural elements are revealed. (1) Y-Family DNAPs have discreet non-covalent contacts between their little finger-domain (LF-Domain) and their catalytic core-domain (CC-Domain), which we call "non-covalent bridges" (NCBs). Arg37 and Arg38 in DNAP IV's CC-Domain near the active site form a non-covalent bridge (AS-NCB) by interacting with Glu251 and Asp252, respectively, in DNAP IV's LF-Domain. Without these interactions dATP/dGTP/dTTP misinsertions increase. DNAP IV's AS-NCB suppresses misinsertions better than Dpo4's equivalent AS-NCB. (2) DNAP IV also suppresses dATP/dGTP/dTTP misinsertions via a second non-covalent bridge, which is ∼8Å from the active site (Distal-NCB). Dpo4 has no Distal-NCB, rendering it inferior at dATP/dGTP/dTTP suppression. (3) dCTP insertion is facilitated by the larger minor groove opening near the active site in DNAP IV versus Dpo4, which is sensible given that Watson/Crick-like [dCTP:BP-N(2)-dG] pairing requires the BP-moiety to be in the minor groove. (4) Compared to Dpo4, DNAP IV has a smaller major groove opening, which suppresses dGTP misinsertion, implying BP-N(2)-dG bulk in the major groove during Hoogsteen syn-adduct-dG:dGTP pairing. In summary, DNAP IV has a large minor groove opening to enhance dCTP insertion, a plugged major groove opening to suppress dGTP misinsertion, and two non-covalent bridges (near and distal

  17. Avaliação de projeto político-pedagógico pelos funcionários: espaços e representatividade Evaluation of a political-pedagogical project by the university staff: spaces and representativeness

    Directory of Open Access Journals (Sweden)

    Jorge Luís Moreira Alberto

    2008-11-01

    Full Text Available Os estudos, de diferentes vertentes e enfoques, afirmam que o processo de educação escolarizada não se reduz à sala de aula e se viabiliza pela ação articulada entre todos os agentes educativos. Preocupando-nos com o baixo protagonismo dos funcionários (corpo técnico-administrativo na construção do projeto político-pedagógico e levando em conta o fato de que os debates não têm enfocado regiões periféricas do processo pedagógico, o presente texto é parte de uma pesquisa mais ampla, de natureza quali-quantitativa, no campo da avaliação institucional, e tem como objeto de reflexão o espaço do Projeto Político-Pedagógico de uma Universidade e suas Unidades Acadêmicas, a partir da representatividade e avaliação desse Projeto pelos funcionários.Research based on different purposes and focuses suggest that the formal education process cannot be reduced to the classroom environment and must also take place through articulated action between all educational participants. Concerned with the low level of participation of staff members in the elaboration of a political-pedagogical project and taking into account the fact that discussions have not focused on peripheral aspects of the pedagogical process, this paper was originated from a broader quali-quantitative research in the field of institutional evaluation and aims at reflecting about the space of the Political-Pedagogical Project in a University and its Academic Units, based on the representation and evaluation of this Project by the staff.

  18. Testimony of Dr. Raul A. Deju, Basalt Waste Isolation Project, before the Subcommittee on Energy Research and Production, Committee on Sceince and Technology, United States House of Representatives, March 2, 1983

    Energy Technology Data Exchange (ETDEWEB)

    1983-01-01

    Status of the Basalt Waste Isolation Project is given. Three key concerns have been identified that need to be resolved to either confirm or eliminate the basalts as a potential nuclear waste repository host medium. They are: A thorough understanding of the groundwater hydrology beneath the Hanford Site is needed to assure that a repository in basalt will not contribute unacceptable amounts of contaminants to the accessible environment. Our ability to construct a repository shaft and a network of underground tunnels needs to be fully demonstrated through an exploratory shaft program. Our ability to ultimately seal a repository, such that its integrity and the isolation of the waste are guaranteed, needs to be demonstrated.

  19. Health- and Taste-Related Attitudes Associated with Dietary Patterns in a Representative Sample of Polish Girls and Young Women: A Cross-Sectional Study (GEBaHealth Project).

    Science.gov (United States)

    Kowalkowska, Joanna; Lonnie, Marta; Wadolowska, Lidia; Czarnocinska, Jolanta; Jezewska-Zychowicz, Marzena; Babicz-Zielinska, Ewa

    2018-02-23

    Attitudes can be predictors of certain health-related behaviours. The attitudes of young females towards health and taste have not been yet fully examined and their associations with dietary behaviours remain unclear. The aim of the study was to investigate if attitudes are associated with dietary patterns in a representative sample of Polish girls. The study population consisted of 1107 girls, aged 13-21 and living in Poland. Attitudes were assessed using the Health and Taste Attitudes Scale (HTAS) and categorised as negative, neutral or positive. Dietary data was obtained using a Food Frequency Questionnaire. Dietary patterns (DPs), derived previously with a Principal Component Analysis (PCA), were 'Traditional Polish', 'Fruit and vegetables', 'Fast food and sweets' and 'Dairy and fats'. The associations between attitudes and DPs were assessed using Spearman's correlation coefficients and logistic regression. The reference group were girls with neutral attitudes. Odds ratios (ORs) were adjusted for age, socioeconomic status (SES), and body mass index (BMI). The correlations between attitudes and DPs ranged from -0.28 for attitudes towards health and 'Fast food and sweets' and 'Traditional Polish' DPs to 0.33 for attitudes towards health and the 'Fruit and vegetables' DP ( p girls and young women, positive attitudes towards health should be strengthened and supported by emphasizing the sensory values of pro-healthy foods.

  20. Health- and Taste-Related Attitudes Associated with Dietary Patterns in a Representative Sample of Polish Girls and Young Women: A Cross-Sectional Study (GEBaHealth Project)

    Science.gov (United States)

    Lonnie, Marta; Wadolowska, Lidia; Czarnocinska, Jolanta; Jezewska-Zychowicz, Marzena; Babicz-Zielinska, Ewa

    2018-01-01

    Attitudes can be predictors of certain health-related behaviours. The attitudes of young females towards health and taste have not been yet fully examined and their associations with dietary behaviours remain unclear. The aim of the study was to investigate if attitudes are associated with dietary patterns in a representative sample of Polish girls. The study population consisted of 1107 girls, aged 13–21 and living in Poland. Attitudes were assessed using the Health and Taste Attitudes Scale (HTAS) and categorised as negative, neutral or positive. Dietary data was obtained using a Food Frequency Questionnaire. Dietary patterns (DPs), derived previously with a Principal Component Analysis (PCA), were ‘Traditional Polish’, ‘Fruit and vegetables’, ‘Fast food and sweets’ and ‘Dairy and fats’. The associations between attitudes and DPs were assessed using Spearman’s correlation coefficients and logistic regression. The reference group were girls with neutral attitudes. Odds ratios (ORs) were adjusted for age, socioeconomic status (SES), and body mass index (BMI). The correlations between attitudes and DPs ranged from −0.28 for attitudes towards health and ‘Fast food and sweets’ and ‘Traditional Polish’ DPs to 0.33 for attitudes towards health and the ‘Fruit and vegetables’ DP (p food and sweets’ DP (OR: 10.93; 95% CI: 3.32–36.01) and between positive attitudes towards health and the ‘Fruit and vegetables’ DP (OR: 5.10; 3.11–8.37). The strongest associations within taste-related HTAS subscales were observed between positive attitudes towards craving for sweet foods and the ‘Traditional Polish’ DP (OR: 1.93; 1.43–2.61) and between positive attitudes towards using food as a reward and the ‘Dairy and fats’ DP (OR: 2.08; 1.22–3.55) as well as the ‘Fast food and sweets’ DP (OR: 2.07; 1.14–3.74). Positive attitudes towards health were associated with a pro-healthy dietary pattern characterised by the consumption of

  1. Health- and Taste-Related Attitudes Associated with Dietary Patterns in a Representative Sample of Polish Girls and Young Women: A Cross-Sectional Study (GEBaHealth Project

    Directory of Open Access Journals (Sweden)

    Joanna Kowalkowska

    2018-02-01

    Full Text Available Attitudes can be predictors of certain health-related behaviours. The attitudes of young females towards health and taste have not been yet fully examined and their associations with dietary behaviours remain unclear. The aim of the study was to investigate if attitudes are associated with dietary patterns in a representative sample of Polish girls. The study population consisted of 1107 girls, aged 13–21 and living in Poland. Attitudes were assessed using the Health and Taste Attitudes Scale (HTAS and categorised as negative, neutral or positive. Dietary data was obtained using a Food Frequency Questionnaire. Dietary patterns (DPs, derived previously with a Principal Component Analysis (PCA, were ‘Traditional Polish’, ‘Fruit and vegetables’, ‘Fast food and sweets’ and ‘Dairy and fats’. The associations between attitudes and DPs were assessed using Spearman’s correlation coefficients and logistic regression. The reference group were girls with neutral attitudes. Odds ratios (ORs were adjusted for age, socioeconomic status (SES, and body mass index (BMI. The correlations between attitudes and DPs ranged from −0.28 for attitudes towards health and ‘Fast food and sweets’ and ‘Traditional Polish’ DPs to 0.33 for attitudes towards health and the ‘Fruit and vegetables’ DP (p < 0.05. In the logistic regression analysis, the strongest associations within health-related HTAS subscales were observed between negative attitudes towards natural products and the ‘Fast food and sweets’ DP (OR: 10.93; 95% CI: 3.32–36.01 and between positive attitudes towards health and the ‘Fruit and vegetables’ DP (OR: 5.10; 3.11–8.37. The strongest associations within taste-related HTAS subscales were observed between positive attitudes towards craving for sweet foods and the ‘Traditional Polish’ DP (OR: 1.93; 1.43–2.61 and between positive attitudes towards using food as a reward and the ‘Dairy and fats’ DP (OR: 2.08; 1

  2. Yucca Mountain Climate Technical Support Representative

    International Nuclear Information System (INIS)

    Sharpe, Saxon E

    2007-01-01

    The primary objective of Project Activity ORD-FY04-012, 'Yucca Mountain Climate Technical Support Representative', was to provide the Office of Civilian Radioactive Waste Management (OCRWM) with expertise on past, present, and future climate scenarios and to support the technical elements of the Yucca Mountain Project (YMP) climate program. The Climate Technical Support Representative was to explain, defend, and interpret the YMP climate program to the various audiences during Site Recommendation and License Application. This technical support representative was to support DOE management in the preparation and review of documents, and to participate in comment response for the Final Environmental Impact Statement, the Site Recommendation Hearings, the NRC Sufficiency Comments, and other forums as designated by DOE management. Because the activity was terminated 12 months early and experience a 27% reduction in budget, it was not possible to complete all components of the tasks as originally envisioned. Activities not completed include the qualification of climate datasets and the production of a qualified technical report. The following final report is an unqualified summary of the activities that were completed given the reduced time and funding

  3. Representative process sampling - in practice

    DEFF Research Database (Denmark)

    Esbensen, Kim; Friis-Pedersen, Hans Henrik; Julius, Lars Petersen

    2007-01-01

    Didactic data sets representing a range of real-world processes are used to illustrate "how to do" representative process sampling and process characterisation. The selected process data lead to diverse variogram expressions with different systematics (no range vs. important ranges; trends and....../or periodicity; different nugget effects and process variations ranging from less than one lag to full variogram lag). Variogram data analysis leads to a fundamental decomposition into 0-D sampling vs. 1-D process variances, based on the three principal variogram parameters: range, sill and nugget effect...

  4. Catalogue of representative meteor spectra

    Czech Academy of Sciences Publication Activity Database

    Vojáček, Vlastimil; Borovička, Jiří; Koten, Pavel; Spurný, Pavel; Štork, Rostislav

    2015-01-01

    Roč. 580, August (2015), A67/1-A67/31 ISSN 0004-6361 R&D Projects: GA ČR(CZ) GAP209/11/1382 Institutional support: RVO:67985815 Keywords : meteorites * meteors * meteoroids Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 4.378, year: 2014

  5. Marc Treib: Representing Landscape Architecture

    DEFF Research Database (Denmark)

    Braae, Ellen Marie

    2008-01-01

    The editor of Representing Landscape Architecture, Marc Treib, argues that there is good reason to evaluate the standard practices of representation that landscape architects have been using for so long. In the rush to the promised land of computer design these practices are now in danger of being...

  6. Does representative wind information exist?

    NARCIS (Netherlands)

    Wieringa, J.

    1996-01-01

    Representativity requirements are discussed for various wind data users. It is shown that most applications can be dealt with by using data from wind stations when these are made to conform with WMO specifications. Methods to achieve this WMO normalization are reviewed, giving minimum specifications

  7. OAS :: Member States : Permanent Representatives

    Science.gov (United States)

    Rights Actions against Corruption C Children Civil Registry Civil Society Contact Us Culture Cyber Barbados Belize Bolivia Brazil Canada Chile Colombia Costa Rica Cuba 1 Dominica (Commonwealth of) Dominican Gutierez Ambassador, Permanent Representative of Belize Diego Pary Rodríguez Bolivia Diego Pary Rodríguez

  8. Judgments of and by Representativeness

    Science.gov (United States)

    1981-05-15

    p. 4i). This hy- pothesis was studied in several contexts, including intuitive statisti- cal judgments and the prediction of professional choice (Kahneman... professional choice . Here, X is representative of M either because it is frequently associated with M (e.g., high fever commonly accompanies pneumonia

  9. WIPP facility representative program plan

    International Nuclear Information System (INIS)

    1994-01-01

    This plan describes the Department of Energy (DOE), Carlsbad Area Office (CAO) facility representative (FR) program at the Waste Isolation Pilot Plant (WIPP). It provides the following information: (1) FR and support organization authorities and responsibilities; (2) FR program requirements; and (3) FR training and qualification requirements

  10. Burnout in Customer Service Representatives

    Directory of Open Access Journals (Sweden)

    Tariq Jalees

    2008-09-01

    Full Text Available The purpose and aim of this research was to (1 identify the factors that contributes towards job burnout in sales service representative (2 What are the relationships of these factors (3 To empirically test the relationships of the determinants relating to burnout in customer service representatives. Based on literature survey six different variables related to burnout were identified. The variables were (1 Emotional exhaustion.(2 Reduced personal accomplishment.(3 Job induced tension.(4 Job satisfaction.(5 Workload (6 Job satisfaction.Each of the variables contained 3 sub-variables. Five different hypotheses were developed and tested through techniques such as Z-test, F-test and regression analysis. The questionnaire administered for the study contained 15 questions including personal data. The subject was Moblink company customers sales service representative in Karachi.The valid sample size was 98 drawn through multi-cluster technique. Techniques such as measure of dispersion and measure of central tendencies were used for analyzing the data. Regression, Z-test, and F-test were used for testing the developed hypothesis.According to the respondents’ opinions, the reduced personal accomplishment had a high rating with a mean of 3.75 and job induced tension has the lowest mean of 3.58. The standard deviation of respondents’ opinions was highest for dimension depersonalization and least for dimension work load. This indicates that there is a high polarization of the respondents’ opinions on the dimension depersonalization moral and least on the dimension work load.The Skew nesses for all the dimensions were in negative except the determinants emotional exhaustion and workload. This indicates that the majority of respondents’ opinions on all the dimensions were below the mean except in the case of emotional exhaustion and workload.Five hypotheses were developed and tested:a The hypothesis relating to low level of burnout in customers

  11. Representing culture in interstellar messages

    Science.gov (United States)

    Vakoch, Douglas A.

    2008-09-01

    As scholars involved with the Search for Extraterrestrial Intelligence (SETI) have contemplated how we might portray humankind in any messages sent to civilizations beyond Earth, one of the challenges they face is adequately representing the diversity of human cultures. For example, in a 2003 workshop in Paris sponsored by the SETI Institute, the International Academy of Astronautics (IAA) SETI Permanent Study Group, the International Society for the Arts, Sciences and Technology (ISAST), and the John Templeton Foundation, a varied group of artists, scientists, and scholars from the humanities considered how to encode notions of altruism in interstellar messages . Though the group represented 10 countries, most were from Europe and North America, leading to the group's recommendation that subsequent discussions on the topic should include more globally representative perspectives. As a result, the IAA Study Group on Interstellar Message Construction and the SETI Institute sponsored a follow-up workshop in Santa Fe, New Mexico, USA in February 2005. The Santa Fe workshop brought together scholars from a range of disciplines including anthropology, archaeology, chemistry, communication science, philosophy, and psychology. Participants included scholars familiar with interstellar message design as well as specialists in cross-cultural research who had participated in the Symposium on Altruism in Cross-cultural Perspective, held just prior to the workshop during the annual conference of the Society for Cross-cultural Research . The workshop included discussion of how cultural understandings of altruism can complement and critique the more biologically based models of altruism proposed for interstellar messages at the 2003 Paris workshop. This paper, written by the chair of both the Paris and Santa Fe workshops, will explore the challenges of communicating concepts of altruism that draw on both biological and cultural models.

  12. Semantic Representatives of the Concept

    Directory of Open Access Journals (Sweden)

    Elena N. Tsay

    2013-01-01

    Full Text Available In the article concept as one of the principle notions of cognitive linguistics is investigated. Considering concept as culture phenomenon, having language realization and ethnocultural peculiarities, the description of the concept “happiness” is presented. Lexical and semantic paradigm of the concept of happiness correlates with a great number of lexical and semantic variants. In the work semantic representatives of the concept of happiness, covering supreme spiritual values are revealed and semantic interpretation of their functioning in the Biblical discourse is given.

  13. Conspicuous Waste and Representativeness Heuristic

    Directory of Open Access Journals (Sweden)

    Tatiana M. Shishkina

    2017-12-01

    Full Text Available The article deals with the similarities between conspicuous waste and representativeness heuristic. The conspicuous waste is analyzed according to the classic Veblen’ interpretation as a strategy to increase social status through conspicuous consumption and conspicuous leisure. In “The Theory of the Leisure Class” Veblen introduced two different types of utility – conspicuous and functional. The article focuses on the possible benefits of the analysis of conspicuous utility not only in terms of institutional economic theory, but also in terms of behavioral economics. To this end, the representativeness heuristics is considered, on the one hand, as a way to optimize the decision-making process, which allows to examine it in comparison with procedural rationality by Simon. On the other hand, it is also analyzed as cognitive bias within the Kahneman and Twersky’ approach. The article provides the analysis of the patterns in the deviations from the rational behavior strategy that could be observed in case of conspicuous waste both in modern market economies in the form of conspicuous consumption and in archaic economies in the form of gift-exchange. The article also focuses on the marketing strategies for luxury consumption’ advertisement. It highlights the impact of the symbolic capital (in Bourdieu’ interpretation on the social and symbolic payments that actors get from the act of conspicuous waste. This allows to perform a analysis of conspicuous consumption both as a rational way to get the particular kind of payments, and, at the same time, as a form of institutionalized cognitive bias.

  14. Representative mass reduction in sampling

    DEFF Research Database (Denmark)

    Petersen, Lars; Esbensen, Harry Kim; Dahl, Casper Kierulf

    2004-01-01

    We here present a comprehensive survey of current mass reduction principles and hardware available in the current market. We conduct a rigorous comparison study of the performance of 17 field and/or laboratory instruments or methods which are quantitatively characterized (and ranked) for accuracy...... dividers, the Boerner Divider, the ??spoon method??, alternate/fractional shoveling and grab sampling. Only devices based on riffle splitting principles (static or rotational) passes the ultimate representativity test (with minor, but significant relative differences). Grab sampling, the overwhelmingly...... most often used mass reduction method, performs appallingly?its use must be discontinued (with the singular exception for completely homogenized fine powders). Only proper mass reduction (i.e. carried out in complete compliance with all appropriate design principles, maintenance and cleaning rules) can...

  15. Ceramics Technology Project database: September 1991 summary report. [Materials for piston ring-cylinder liner for advanced heat/diesel engines

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, B.L.P.

    1992-06-01

    The piston ring-cylinder liner area of the internal combustion engine must withstand very-high-temperature gradients, highly-corrosive environments, and constant friction. Improving the efficiency in the engine requires ring and cylinder liner materials that can survive this abusive environment and lubricants that resist decomposition at elevated temperatures. Wear and friction tests have been done on many material combinations in environments similar to actual use to find the right materials for the situation. This report covers tribology information produced from 1986 through July 1991 by Battelle columbus Laboratories, Caterpillar Inc., and Cummins Engine Company, Inc. for the Ceramic Technology Project (CTP). All data in this report were taken from the project's semiannual and bimonthly progress reports and cover base materials, coatings, and lubricants. The data, including test rig descriptions and material characterizations, are stored in the CTP database and are available to all project participants on request. Objective of this report is to make available the test results from these studies, but not to draw conclusions from these data.

  16. PSCAD Modules Representing PV Generator

    Energy Technology Data Exchange (ETDEWEB)

    Muljadi, E.; Singh, M.; Gevorgian, V.

    2013-08-01

    Photovoltaic power plants (PVPs) have been growing in size, and the installation time is very short. With the cost of photovoltaic (PV) panels dropping in recent years, it can be predicted that in the next 10 years the contribution of PVPs to the total number of renewable energy power plants will grow significantly. In this project, the National Renewable Energy Laboratory (NREL) developed a dynamic modeling of the modules to be used as building blocks to develop simulation models of single PV arrays, expanded to include Maximum Power Point Tracker (MPPT), expanded to include PV inverter, or expanded to cover an entire PVP. The focus of the investigation and complexity of the simulation determines the components that must be included in the simulation. The development of the PV inverter was covered in detail, including the control diagrams. Both the current-regulated voltage source inverter and the current-regulated current source inverter were developed in PSCAD. Various operations of the PV inverters were simulated under normal and abnormal conditions. Symmetrical and unsymmetrical faults were simulated, presented, and discussed. Both the three-phase analysis and the symmetrical component analysis were included to clarify the understanding of unsymmetrical faults. The dynamic model validation was based on the testing data provided by SCE. Testing was conducted at SCE with the focus on the grid interface behavior of the PV inverter under different faults and disturbances. The dynamic model validation covers both the symmetrical and unsymmetrical faults.

  17. Want change? Call your representative

    Science.gov (United States)

    Fischhoff, Ilya R.

    2011-07-01

    During my tenure as an AGU Congressional Science Fellow, which began in September 2010 and continues until November 2011, my time has been shared between working with the U.S. House of Representatives Natural Resource Committee Democratic staff and in the office of Rep. Ed Markey (D-Mass., ranking Democrat on the committee). I appreciate getting to work with staff, fellows, and interns who inspire me, make me laugh, and know their issues cold. Much of my work on the committee is related to fish, wildlife, oceans, lands, and water issues and is directly related to my background in ecology and evolutionary biology (I studied zebra ecology and behavior in Kenya). My assignments have included asking the Environmental Protection Agency (EPA) about why it has not changed the allowed usage of certain pesticides that the National Marine Fisheries Service has found to jeopardize the recovery of endangered Pacific salmon; helping to identify research needs and management options to combat the swiftly spreading and catastrophic white nose syndrome in North American bats; and inquiring as to whether a captive-ape welfare bill, if passed without amendment, could thwart development of a vaccine to stop the Ebola virus from continuing to cause mass mortality in endangered wild apes.

  18. 40 CFR 197.31 - What is a representative volume?

    Science.gov (United States)

    2010-07-01

    ... supply a given water demand. The DOE must project the concentration of radionuclides released from the... Public Health and Environmental Standards for Disposal Ground Water Protection Standards § 197.31 What is a representative volume? (a) It is the volume of ground water that would be withdrawn annually from...

  19. Guidelines for Automation Project Execution

    OpenAIRE

    Takkinen, Heidi

    2011-01-01

    The purpose of this Master’s thesis was to create instructions for executing an automation project. Sarlin Oy Ab needed directions on how to execute an automation project. Sarlin is starting up a new business area offering total project solutions for customers. Sarlin focuses on small and minor automation projects on domestic markets. The thesis represents issues related to project execution starting from the theory of the project to its kick-off and termination. Site work is one importan...

  20. Permitted Marine Hydrokinetic Projects

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data represents pending or issued preliminary permits or issued licenses for marine hydrokinetic projects that produce energy from waves or directly from the...

  1. Multicriteria analysis of ontologically represented information

    Science.gov (United States)

    Wasielewska, K.; Ganzha, M.; Paprzycki, M.; Bǎdicǎ, C.; Ivanovic, M.; Lirkov, I.

    2014-11-01

    Our current work concerns the development of a decision support system for the software selection problem. The main idea is to utilize expert knowledge to help the user in selecting the best software / method / computational resource to solve a computational problem. Obviously, this involves multicriterial decision making and the key open question is: which method to choose. The context of the work is provided by the Agents in Grid (AiG) project, where the software selection (and thus multicriterial analysis) is to be realized when all information concerning the problem, the hardware and the software is ontologically represented. Initially, we have considered the Analytical Hierarchy Process (AHP), which is well suited for the hierarchical data structures (e.g., such that have been formulated in terms of ontologies). However, due to its well-known shortcomings, we have decided to extend our search for the multicriterial analysis method best suited for the problem in question. In this paper we report results of our search, which involved: (i) TOPSIS (Technique for Order Preference by Similarity to Ideal Solution), (ii) PROMETHEE, and (iii) GRIP (Generalized Regression with Intensities of Preference). We also briefly argue why other methods have not been considered as valuable candidates.

  2. FLORAM project

    Energy Technology Data Exchange (ETDEWEB)

    Zulauf, W E [Sao Paolos Environmental Secretariat, Sao Paolo (Brazil); Goelho, A S.R. [Riocell, S.A. (Brazil); Saber, A [IEA-Instituto de Estudos Avancados (Brazil); and others

    1996-12-31

    The project FLORAM was formulated at the `Institute for Advanced Studies` of the University of Sao Paulo. It aims at decreasing the level of carbon dioxide in the atmosphere and thus curbing the green-house effect by way of a huge effort of forestation and reforestation. The resulting forests when the trees mature, will be responsible for the absorption of about 6 billion tons of excess carbon. It represents 5 % of the total amount of CO{sub 2} which is in excess in the earth`s atmosphere and represents 5 % of the available continental surfaces which can be forested as well. Therefore, if similar projects are implemented throughout the world, in theory all the exceeding CO{sub 2}, responsible for the `greenhouse effect`, (27 % or 115 billion tons of carbon) would be absorbed. Regarding this fact, there would be a 400 million hectar increase of growing forests. FLORAM in Brazil aims to plant 20.000.000 ha in 2 years at a cost of 20 billion dollars. If it reaches its goals that will mean that Brazil will have reforested an area almost half as big as France. (author)

  3. FLORAM project

    Energy Technology Data Exchange (ETDEWEB)

    Zulauf, W.E. [Sao Paolos Environmental Secretariat, Sao Paolo (Brazil); Goelho, A.S.R. [Riocell, S.A. (Brazil); Saber, A. [IEA-Instituto de Estudos Avancados (Brazil)] [and others

    1995-12-31

    The project FLORAM was formulated at the `Institute for Advanced Studies` of the University of Sao Paulo. It aims at decreasing the level of carbon dioxide in the atmosphere and thus curbing the green-house effect by way of a huge effort of forestation and reforestation. The resulting forests when the trees mature, will be responsible for the absorption of about 6 billion tons of excess carbon. It represents 5 % of the total amount of CO{sub 2} which is in excess in the earth`s atmosphere and represents 5 % of the available continental surfaces which can be forested as well. Therefore, if similar projects are implemented throughout the world, in theory all the exceeding CO{sub 2}, responsible for the `greenhouse effect`, (27 % or 115 billion tons of carbon) would be absorbed. Regarding this fact, there would be a 400 million hectar increase of growing forests. FLORAM in Brazil aims to plant 20.000.000 ha in 2 years at a cost of 20 billion dollars. If it reaches its goals that will mean that Brazil will have reforested an area almost half as big as France. (author)

  4. Organization of project management

    International Nuclear Information System (INIS)

    Schmidt, R.

    1975-01-01

    When speaking about interfaces within a project and their management, one has to understand and define what an interface is. In general, each component facing another one and each person working on a project with another person represents an interface. Therefore a project will consist practically in its entirety of interfaces with components and people sandwiched between them. This paper is limited to the most important interfaces with a focus on the problems occuring at them and their resolution. (orig.) [de

  5. OAS :: Authorities : Permanent Representatives to the OAS

    Science.gov (United States)

    Rights Actions against Corruption C Children Civil Registry Civil Society Contact Us Culture Cyber Representative of Belize Diego Pary Rodríguez Bolivia Diego Pary Rodríguez Ambassador, Permanent Representative of Bolivia José Luiz Machado Brazil José Luiz Machado e Costa Ambassador, Permanent Representative

  6. Web Based Project Management System

    OpenAIRE

    Aadamsoo, Anne-Mai

    2010-01-01

    To increase an efficiency of a product, nowadays many web development companies are using different project management systems. A company may run a number of projects at a time, and requires input from a number of individuals, or teams for a multi level development plan, whereby a good project management system is needed. Project management systems represent a rapidly growing technology in IT industry. As the number of users, who utilize project management applications continues to grow, w...

  7. Project Notes

    Science.gov (United States)

    School Science Review, 1978

    1978-01-01

    Presents sixteen project notes developed by pupils of Chipping Norton School and Bristol Grammar School, in the United Kingdom. These Projects include eight biology A-level projects and eight Chemistry A-level projects. (HM)

  8. Represented Speech in Qualitative Health Research

    DEFF Research Database (Denmark)

    Musaeus, Peter

    2017-01-01

    Represented speech refers to speech where we reference somebody. Represented speech is an important phenomenon in everyday conversation, health care communication, and qualitative research. This case will draw first from a case study on physicians’ workplace learning and second from a case study...... on nurses’ apprenticeship learning. The aim of the case is to guide the qualitative researcher to use own and others’ voices in the interview and to be sensitive to represented speech in everyday conversation. Moreover, reported speech matters to health professionals who aim to represent the voice...... of their patients. Qualitative researchers and students might learn to encourage interviewees to elaborate different voices or perspectives. Qualitative researchers working with natural speech might pay attention to how people talk and use represented speech. Finally, represented speech might be relevant...

  9. Representative Sampling for reliable data analysis

    DEFF Research Database (Denmark)

    Petersen, Lars; Esbensen, Kim Harry

    2005-01-01

    regime in order to secure the necessary reliability of: samples (which must be representative, from the primary sampling onwards), analysis (which will not mean anything outside the miniscule analytical volume without representativity ruling all mass reductions involved, also in the laboratory) and data...

  10. 14 CFR 1274.906 - Designation of New Technology Representative and Patent Representative.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Designation of New Technology... Conditions § 1274.906 Designation of New Technology Representative and Patent Representative. Designation of New Technology Representative and Patent Representative July 2002 (a) For purposes of administration...

  11. Verification of Representative Sampling in RI waste

    International Nuclear Information System (INIS)

    Ahn, Hong Joo; Song, Byung Cheul; Sohn, Se Cheul; Song, Kyu Seok; Jee, Kwang Yong; Choi, Kwang Seop

    2009-01-01

    For evaluating the radionuclide inventories for RI wastes, representative sampling is one of the most important parts in the process of radiochemical assay. Sampling to characterized RI waste conditions typically has been based on judgment or convenience sampling of individual or groups. However, it is difficult to get a sample representatively among the numerous drums. In addition, RI waste drums might be classified into heterogeneous wastes because they have a content of cotton, glass, vinyl, gloves, etc. In order to get the representative samples, the sample to be analyzed must be collected from selected every drum. Considering the expense and time of analysis, however, the number of sample has to be minimized. In this study, RI waste drums were classified by the various conditions of the half-life, surface dose, acceptance date, waste form, generator, etc. A sample for radiochemical assay was obtained through mixing samples of each drum. The sample has to be prepared for radiochemical assay and although the sample should be reasonably uniform, it is rare that a completely homogeneous material is received. Every sample is shredded by a 1 ∼ 2 cm 2 diameter and a representative aliquot taken for the required analysis. For verification of representative sampling, classified every group is tested for evaluation of 'selection of representative drum in a group' and 'representative sampling in a drum'

  12. Representing Uncertainty by Probability and Possibility

    DEFF Research Database (Denmark)

    of uncertain parameters. Monte Carlo simulation is readily used for practical calculations. However, an alternative approach is offered by possibility theory making use of possibility distributions such as intervals and fuzzy intervals. This approach is well suited to represent lack of knowledge or imprecision......Uncertain parameters in modeling are usually represented by probability distributions reflecting either the objective uncertainty of the parameters or the subjective belief held by the model builder. This approach is particularly suited for representing the statistical nature or variance...

  13. Services Subcontract Technical Representative (STR) handbook

    International Nuclear Information System (INIS)

    Houston, D.H.

    1997-06-01

    The purpose of this handbook is to provide guidance to Bechtel Hanford, Inc. Subcontract Representatives in their assignments. It is the intention of this handbook to ensure that subcontract work is performed in accordance with the subcontract documents

  14. REFractions: The Representing Equivalent Fractions Game

    Science.gov (United States)

    Tucker, Stephen I.

    2014-01-01

    Stephen Tucker presents a fractions game that addresses a range of fraction concepts including equivalence and computation. The REFractions game also improves students' fluency with representing, comparing and adding fractions.

  15. Representing Boolean Functions by Decision Trees

    KAUST Repository

    Chikalov, Igor

    2011-01-01

    A Boolean or discrete function can be represented by a decision tree. A compact form of decision tree named binary decision diagram or branching program is widely known in logic design [2, 40]. This representation is equivalent to other forms

  16. Request by the Resident Representative of Iraq

    International Nuclear Information System (INIS)

    1990-01-01

    The attached clarification by a spokesman of the Iraqi Ministry of Foreign Affairs is being circulated for the information of Member States pursuant to a request made by the Resident Representative of Iraq

  17. Crisis Relocation Workshops for Transportation Industry Representatives

    Science.gov (United States)

    1979-12-01

    executive, two National Guard members, one Air Force transporta- _a ,tion representative, two Red Cross representatives, one school bus z coordinators...manaaers, local transitCD operator, and miiltary busingA authorityA Local Governa-ient 2 Fire chief, assistantI Air Force 3 Liaison Support D CPA :z...to attend the workshop. Majur trans- portation problems anticipated during crisis relocation include: 1. Transportation of carless residents; 2. The

  18. Raspberry Pi projects

    CERN Document Server

    Robinson, Andrew

    2013-01-01

    Learn to build software and hardware projects featuring the Raspberry Pi! Raspberry Pi represents a new generation of computers that encourages the user to play and to learn and this unique book is aimed at the beginner Raspberry Pi user who is eager to get started creating real-world projects. Taking you on a journey of creating 15 practical projects, this fun and informative resource introduces you to the skills you need to have in order to make the most of the Pi. The book begins with a quick look at how to get the Pi up and running and then encourages you to dive into the array of exciti

  19. Define Project

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas

    2005-01-01

    "Project" is a key concept in IS management. The word is frequently used in textbooks and standards. Yet we seldom find a precise definition of the concept. This paper discusses how to define the concept of a project. The proposed definition covers both heavily formalized projects and informally...... organized, agile projects. Based on the proposed definition popular existing definitions are discussed....

  20. Project Management

    DEFF Research Database (Denmark)

    Project Management Theory Meets Practice contains the proceedings from the 1st Danish Project Management Research Conference (DAPMARC 2015), held in Copenhagen, Denmark, on May 21st, 2015.......Project Management Theory Meets Practice contains the proceedings from the 1st Danish Project Management Research Conference (DAPMARC 2015), held in Copenhagen, Denmark, on May 21st, 2015....

  1. Project Management

    DEFF Research Database (Denmark)

    Pilkington, Alan; Chai, Kah-Hin; Le, Yang

    2015-01-01

    This paper identifies the true coverage of PM theory through a bibliometric analysis of the International Journal of Project Management from 1996-2012. We identify six persistent research themes: project time management, project risk management, programme management, large-scale project management......, project success/failure and practitioner development. These differ from those presented in review and editorial articles in the literature. In addition, topics missing from the PM BOK: knowledge management project-based organization and project portfolio management have become more popular topics...

  2. Project financing

    International Nuclear Information System (INIS)

    Cowan, A.

    1998-01-01

    Project financing was defined ('where a lender to a specific project has recourse only to the cash flow and assets of that project for repayment and security respectively') and its attributes were described. Project financing was said to be particularly well suited to power, pipeline, mining, telecommunications, petro-chemicals, road construction, and oil and gas projects, i.e. large infrastructure projects that are difficult to fund on-balance sheet, where the risk profile of a project does not fit the corporation's risk appetite, or where higher leverage is required. Sources of project financing were identified. The need to analyze and mitigate risks, and being aware that lenders always take a conservative view and gravitate towards the lowest common denominator, were considered the key to success in obtaining project financing funds. TransAlta Corporation's project financing experiences were used to illustrate the potential of this source of financing

  3. Project descriptions

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    This part specifies the activities and project tasks of each project broken down according to types of financing, listing the current projects Lw 1 through 3 funded by long-term provisions (budget), the current projects LB 1 and 2, LG 1 through 5, LK1, LM1, and LU 1 through 6 financed from special funds, and the planned projects ZG 1 through 4 and ZU 1, also financed from special funds. (DG) [de

  4. 48 CFR 1852.227-72 - Designation of new technology representative and patent representative.

    Science.gov (United States)

    2010-10-01

    ... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.227-72 Designation of new technology representative... of New Technology Representative and Patent Representative (JUL 1997) (a) For purposes of administration of the clause of this contract entitled “New Technology” or “Patent Rights—Retention by the...

  5. 14 CFR 1260.58 - Designation of new technology representative and patent representative.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Designation of new technology... of new technology representative and patent representative. Designation of New Technology... of this grant entitled “New Technology,” the following named representatives are hereby designated by...

  6. 40 CFR 60.4112 - Changing Hg designated representative and alternate Hg designated representative; changes in...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Changing Hg designated representative and alternate Hg designated representative; changes in owners and operators. 60.4112 Section 60.4112... Generating Units Hg Designated Representative for Hg Budget Sources § 60.4112 Changing Hg designated...

  7. CLIC project timeline

    CERN Multimedia

    CLIC, Compact Linear Collider Project

    2018-01-01

    The CLIC project timeline. Current plan is to start at sqrt(s)=380 GeV for Higgs and top quark precision physics and upgrade up to 3 TeV. This timeline represent a purely technical schedule and assumes support at the European Strategy for Particle Physics (ESPP) in 2020 and available funding.

  8. The Visual Identity Project

    Science.gov (United States)

    Tennant-Gadd, Laurie; Sansone, Kristina Lamour

    2008-01-01

    Identity is the focus of the middle-school visual arts program at Cambridge Friends School (CFS) in Cambridge, Massachusetts. Sixth graders enter the middle school and design a personal logo as their first major project in the art studio. The logo becomes a way for students to introduce themselves to their teachers and to represent who they are…

  9. Transfer metrics analytics project

    CERN Document Server

    Matonis, Zygimantas

    2016-01-01

    This report represents work done towards predicting transfer rates/latencies on Worldwide LHC Computing Grid (WLCG) sites using Machine Learning techniques. Topic covered are technologies used for the project, data preparation for ML suitable format and attribute selection as well as a comparison of different ML algorithms.

  10. Representing uncertainty on model analysis plots

    Directory of Open Access Journals (Sweden)

    Trevor I. Smith

    2016-09-01

    Full Text Available Model analysis provides a mechanism for representing student learning as measured by standard multiple-choice surveys. The model plot contains information regarding both how likely students in a particular class are to choose the correct answer and how likely they are to choose an answer consistent with a well-documented conceptual model. Unfortunately, Bao’s original presentation of the model plot did not include a way to represent uncertainty in these measurements. I present details of a method to add error bars to model plots by expanding the work of Sommer and Lindell. I also provide a template for generating model plots with error bars.

  11. Representative Democracy in Australian Local Government

    Directory of Open Access Journals (Sweden)

    Colin Hearfield

    2009-01-01

    Full Text Available In an assessment of representative democracy in Australian local government, this paper considers long-run changes in forms of political representation, methods of vote counting, franchise arrangements, numbers of local government bodies and elected representatives, as well as the thorny question of constitutional recognition. This discussion is set against the background of ongoing tensions between the drive for economic efficiency and the maintenance of political legitimacy, along with more deep-seated divisions emerging from the legal relationship between local and state governments and the resultant problems inherent in local government autonomy versus state intervention.

  12. Enhancing policy innovation by redesigning representative democracy

    DEFF Research Database (Denmark)

    Sørensen, Eva

    2016-01-01

    Policy innovation is a key aspect of public innovation, which has been largely overlooked. Political leadership, competition and collaboration are key drivers of policy innovation. It is a barrier in traditional models of representative democracy that they provide weak conditions for collaboration....... Two Danish case studies indicate that collaboration between politicians and relevant and affected stakeholders can promote policy innovation, but also that a redesign of representative democracy is needed in order to establish a productive combination of political leadership, competition...... and collaboration in political life....

  13. Representativeness elements of an hybrid reactor demonstrator

    International Nuclear Information System (INIS)

    Kerdraon, D.; Billebaud, A.; Brissot, R.; David, S.; Giorni, A.; Heuer, D.; Loiseaux, J.M.; Meplan, O.

    2000-11-01

    This document deals with the quantification of the minimum thermal power level for a demonstrator and the definition of the physical criteria which define the representative character of a demonstrator towards a power reactor. Solutions allowing to keep an acceptable flow in an industrial core, have also been studied. The document is divided in three parts: the representativeness elements, the considered solutions and the characterization of the neutrons flows at the interfaces and the dose rates at the outer surface of the vessel. (A.L.B.)

  14. Project studies

    DEFF Research Database (Denmark)

    Geraldi, Joana; Söderlund, Jonas

    2018-01-01

    Project organising is a growing field of scholarly inquiry and management practice. In recent years, two important developments have influenced this field: (1) the study and practice of projects have extended their level of analysis from mainly focussing on individual projects to focussing on micro......, and of the explanations of project practices they could offer. To discuss avenues for future research on projects and project practice, this paper suggests the notion of project studies to better grasp the status of our field. We combine these two sets of ideas to analyse the status and future options for advancing...... project research: (1) levels of analysis; and (2) type of research. Analysing recent developments within project studies, we observe the emergence of what we refer to as type 3 research, which reconciles the need for theoretical development and engagement with practice. Type 3 research suggests pragmatic...

  15. 10 CFR 63.332 - Representative volume.

    Science.gov (United States)

    2010-01-01

    ... water that would be withdrawn annually from an aquifer containing less than 10,000 milligrams of total dissolved solids per liter of water to supply a given water demand. DOE must project the concentration of... REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Ground-Water...

  16. Virtual projects

    DEFF Research Database (Denmark)

    Svejvig, Per; Commisso, Trine Hald

    2012-01-01

    that the best practice knowledge has not permeated sufficiently to the practice. Furthermore, the appropriate application of information and communication technology (ICT) remains a big challenge, and finally project managers are not sufficiently trained in organizing and conducting virtual projects....... The overall implications for research and practice are to acknowledge virtual project management as very different to traditional project management and to address this difference.......Virtual projects are common with global competition, market development, and not least the financial crisis forcing organizations to reduce their costs drastically. Organizations therefore have to place high importance on ways to carry out virtual projects and consider appropriate practices...

  17. Project financing

    International Nuclear Information System (INIS)

    Alvarez, M.U.

    1990-01-01

    This paper presents the basic concepts and components of the project financing of large industrial facilities. Diagrams of a simple partnership structure and a simple leveraged lease structure are included. Finally, a Hypothetical Project is described with basic issues identified for discussion purposes. The topics of the paper include non-recourse financing, principal advantages and objectives, disadvantages, project financing participants and agreements, feasibility studies, organization of the project company, principal agreements in a project financing, insurance, and an examination of a hypothetical project

  18. Attributes Heeded When Representing an Osmosis Problem.

    Science.gov (United States)

    Zuckerman, June Trop

    Eighteen high school science students were involved in a study to determine what attributes in the problem statement they need when representing a typical osmosis problem. In order to realize this goal students were asked to solve problems aloud and to explain their answers. Included as a part of the results are the attributes that the students…

  19. Representing Uncertainty on Model Analysis Plots

    Science.gov (United States)

    Smith, Trevor I.

    2016-01-01

    Model analysis provides a mechanism for representing student learning as measured by standard multiple-choice surveys. The model plot contains information regarding both how likely students in a particular class are to choose the correct answer and how likely they are to choose an answer consistent with a well-documented conceptual model.…

  20. Strong imploding shock, the representative curve

    International Nuclear Information System (INIS)

    Mishkin, E.A.; Alejaldre, C.

    1981-01-01

    The representative curve of the ideal gas behind the front of a spherically, or cylindrically, symmetric strong imploding shock is shown to pass through the point where the reduced pressure is maximum, P(xisub(m)) = Psub(m)sub(a)sub(x). (orig.)

  1. 28 CFR 104.4 - Personal Representative.

    Science.gov (United States)

    2010-07-01

    ... addition, as provided in § 104.21(b)(5) of this part, the Special Master may publish a list of individuals... Special Master may, in his discretion, determine that the Personal Representative for purposes of... administrator of the decedent's estate. In the event no will exists, the Special Master may, in his discretion...

  2. Adjustment Following Disability: Representative Case Studies.

    Science.gov (United States)

    Heinemann, Allen W.; Shontz, Franklin C.

    1984-01-01

    Examined adjustment following physical disability using the representative case method with two persons with quadriplegia. Results highlighted the importance of previously established coping styles as well as the role of the environment in adjustment. Willingness to mourn aided in later growth. (JAC)

  3. Managing projects a team-based approach

    CERN Document Server

    Brown, Karen A

    2010-01-01

    Students today are likely to be assigned to project teams or to be project managers almost immediately in their first job. Managing Projects: A Team-Based Approach was written for a wide range of stakeholders, including project managers, project team members, support personnel, functional mangers who provide resources for projects, project customers (and customer representatives), project sponsors, project subcontractors, and anyone who plays a role in the project delivery process. The need for project management is on the rise as product life cycles compress, demand for IT systems increases, and business takes on an increasingly global character. This book adds to the project management knowledge base in a way that fills an unmet need—it shows how teams can apply many of the standard project management tools, as well as several tools that are relatively new to the field. Managing Projects: A Team-Based Approach offers the academic rigor found in most textbooks along with the practical attributes often foun...

  4. Microsoft project

    OpenAIRE

    Markić, Lucija; Mandušić, Dubravka; Grbavac, Vitomir

    2005-01-01

    Microsoft Project je alat čije su prednosti u svakodnevnom radu nezamjenjive. Pomoću Microsoft Projecta omogućeno je upravljanje resursima, stvaranje izvještaja o projektima u vremenu, te analize različitih scenarija. Pojavljuje u tri verzije: Microsoft Project Professional, Microsoft Project Server i Microsoft Project Server Client Access Licenses. Upravo je trend da suvremeni poslovni ljudi zadatke povjeravaju Microsoft Projectu jer on znatno povećava produktivnost rada. Te prednos...

  5. Project ethics

    CERN Document Server

    Jonasson, Haukur Ingi

    2013-01-01

    How relevant is ethics to project management? The book - which aims to demystify the field of ethics for project managers and managers in general - takes both a critical and a practical look at project management in terms of success criteria, and ethical opportunities and risks. The goal is to help the reader to use ethical theory to further identify opportunities and risks within their projects and thereby to advance more directly along the path of mature and sustainable managerial practice.

  6. STUDENTS’ COMMUNICATION SKILLS ASSESSMENT BY EXTERNAL LECTURERS AND INDUSTRY REPRESENTATIVES

    Directory of Open Access Journals (Sweden)

    NOORFAZILA KAMAL

    2016-11-01

    Full Text Available Soft skills, especially communication skills, are important skills which each graduate must possess. Accordingly, several courses and approaches have been carried out in universities to train students in communication skills. The skills are normally evaluated by course lecturers. However, assessments by a third party from outside the university are valuable so that the students’ ahievements may be weighed against external evaluators’ point of views. In the Department of Electrical, Electronic and Systems Engineering (DEESE, Universiti Kebangsaan Malaysia (UKM, communication skills assessment by external lecturers and industry representatives are performed on Hari Poster JKEES, where students present their final year project poster. There are two categories of evaluation, namely project and communication skills. The project evaluation covers content, result and impact, while communication skills evaluation covers poster layout and design, and delivery. This study only analyse the students’ communication skills achievement. The participants of this study consists of 109 final year students from two batches, of which 51 students are from year 2014 and the other 58 students from year 2015. The results show that for the year 2014 students, the mean mark given by external lecturers in layout and design category is 6.7, while the mean mark from industry evaluators is 6.5. For the 2015 batch, the mean mark in the layout and design category is 6.3 from external lecturers and 5.9 from industry evaluators. In the delivery category, the mean marks for the 2014 batch are 7.1 and 6.6 from external lecturers and industry evaluators, espectively. Meanwhile, for the 2015 batch, the mean marks by external lecturers and industry evaluators are 6.3 and 5.8, respectively. The results show that both external lecturers and industry representatives judged DEESE students’ communication skills to be good.

  7. Representing Boolean Functions by Decision Trees

    KAUST Repository

    Chikalov, Igor

    2011-01-01

    A Boolean or discrete function can be represented by a decision tree. A compact form of decision tree named binary decision diagram or branching program is widely known in logic design [2, 40]. This representation is equivalent to other forms, and in some cases it is more compact than values table or even the formula [44]. Representing a function in the form of decision tree allows applying graph algorithms for various transformations [10]. Decision trees and branching programs are used for effective hardware [15] and software [5] implementation of functions. For the implementation to be effective, the function representation should have minimal time and space complexity. The average depth of decision tree characterizes the expected computing time, and the number of nodes in branching program characterizes the number of functional elements required for implementation. Often these two criteria are incompatible, i.e. there is no solution that is optimal on both time and space complexity. © Springer-Verlag Berlin Heidelberg 2011.

  8. Climate Change and the Representative Agent

    Energy Technology Data Exchange (ETDEWEB)

    Howarth, R.B. [Environmental Studies Program, Dartmouth College, Hanover, New Hampshire 03755 (United States)

    2000-02-01

    The artifice of an infinitely-lived representative agent is commonly invoked to balance the present costs and future benefits of climate stabilization policies. Since actual economies are populated by overlapping generations of finite-lived persons, this approach begs important questions of welfare aggregation. This paper compares the results of representative agent and overlapping generations models that are numerically calibrated based on standard assumptions regarding climate economy interactions. Under two social choice rules - Pareto efficiency and classical utilitarianism - the models generate closely similar simulation results. In the absence of policies to redistribute income between present and future generations, efficient rates of carbon dioxide emissions abatement rise from 15 to 20% between the years 2000 and 2105. Under classical utilitarianism, in contrast, optimal control rates rise from 48 to 79% this same period. 23 refs.

  9. Meeting staff representatives of the European Agencies

    CERN Multimedia

    Staff Association

    2014-01-01

      The AASC (Assembly of Agency Staff Committee) held its 27th Meeting of the specialized European Agencies on 26 and 27 May on the premises of the OHIM (Office for Harmonization in the Internal Market) in Alicante, Spain. Two representatives of the CERN Staff Association, in charge of External Relations, attended as observers. This participation is a useful complement to regular contacts we have with FICSA (Federation of International Civil Servants' Associations), which groups staff associations of the UN Agencies, and the annual CSAIO conferences (Conference of Staff Associations of International Organizations), where each Autumn representatives of international organizations based in Europe meet to discuss themes of common interest to better promote and defend the rights of the international civil servants. All these meetings allow us to remain informed on items that are directly or indirectly related to employment and social conditions of our colleagues in other international and Europ...

  10. Data structures and apparatuses for representing knowledge

    Science.gov (United States)

    Hohimer, Ryan E; Thomson, Judi R; Harvey, William J; Paulson, Patrick R; Whiting, Mark A; Tratz, Stephen C; Chappell, Alan R; Butner, Robert S

    2014-02-18

    Data structures and apparatuses to represent knowledge are disclosed. The processes can comprise labeling elements in a knowledge signature according to concepts in an ontology and populating the elements with confidence values. The data structures can comprise knowledge signatures stored on computer-readable media. The knowledge signatures comprise a matrix structure having elements labeled according to concepts in an ontology, wherein the value of the element represents a confidence that the concept is present in an information space. The apparatus can comprise a knowledge representation unit having at least one ontology stored on a computer-readable medium, at least one data-receiving device, and a processor configured to generate knowledge signatures by comparing datasets obtained by the data-receiving devices to the ontologies.

  11. Limitations of Shallow Networks Representing Finite Mappings

    Czech Academy of Sciences Publication Activity Database

    Kůrková, Věra

    submitted 5.1. (2018) ISSN 0941-0643 R&D Projects: GA ČR GA15-18108S Institutional support: RVO:67985807 Keywords : shallow and deep networks * sparsity * variational norms * functions on large finite domains * concentration of measure * pseudo-noise sequences * perceptron networks Subject RIV: IN - Informatics, Computer Science OBOR OECD: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8) Impact factor: 2.505, year: 2016

  12. Using semantics for representing experimental protocols.

    Science.gov (United States)

    Giraldo, Olga; García, Alexander; López, Federico; Corcho, Oscar

    2017-11-13

    An experimental protocol is a sequence of tasks and operations executed to perform experimental research in biological and biomedical areas, e.g. biology, genetics, immunology, neurosciences, virology. Protocols often include references to equipment, reagents, descriptions of critical steps, troubleshooting and tips, as well as any other information that researchers deem important for facilitating the reusability of the protocol. Although experimental protocols are central to reproducibility, the descriptions are often cursory. There is the need for a unified framework with respect to the syntactic structure and the semantics for representing experimental protocols. In this paper we present "SMART Protocols ontology", an ontology for representing experimental protocols. Our ontology represents the protocol as a workflow with domain specific knowledge embedded within a document. We also present the S ample I nstrument R eagent O bjective (SIRO) model, which represents the minimal common information shared across experimental protocols. SIRO was conceived in the same realm as the Patient Intervention Comparison Outcome (PICO) model that supports search, retrieval and classification purposes in evidence based medicine. We evaluate our approach against a set of competency questions modeled as SPARQL queries and processed against a set of published and unpublished protocols modeled with the SP Ontology and the SIRO model. Our approach makes it possible to answer queries such as Which protocols use tumor tissue as a sample. Improving reporting structures for experimental protocols requires collective efforts from authors, peer reviewers, editors and funding bodies. The SP Ontology is a contribution towards this goal. We build upon previous experiences and bringing together the view of researchers managing protocols in their laboratory work. Website: https://smartprotocols.github.io/ .

  13. The local brand representative in reseller networks

    OpenAIRE

    Gupta, Suraksha; Malhotra, Naresh K; Czinkota, Michael; Foroudi, Pantea

    2016-01-01

    This study investigates the characteristics of local individuals who represent a brand to its resellers by first conceptualizing these characteristics by employing complexity theory and then testing the conceptualization. This research revealed that four characteristics ‘native’, ‘entrepreneurial’, ‘advisor’, and ‘compatible’ are the main ones that influence reseller brand preferences. The study finds a link between reseller brand preference and reseller brand loyalty which is useful for mana...

  14. Citizen's initiatives and the representative system

    International Nuclear Information System (INIS)

    Guggenberger, B.; Kempf, U.

    1978-01-01

    This anthology containing contributions of 19 sociologists is a systematic investigation of the locality, the possibilities and the effective radius of citizen's initiatives under the functional conditions of the parliamentary - representative system. The intellectual and political surroundings, the sociologic context, the institutional, political and judical overall conditions as well as the consequences of this movement for the whole political system of the Federal Republic of Germany. (orig.) [de

  15. Diversity and representativeness: two key factors

    CERN Multimedia

    Staff Association

    2013-01-01

    In the past few weeks many of you have filled out the questionnaire for preparing the upcoming Five-yearly review. Similarly, Staff Association members have elected their delegates to the Staff Council for the coming two years. Once again we would like to thank all those who have taken the time and effort to make their voice heard on these two occasions. Elections to the Staff Council Below we publish the new Staff Council with its forty delegates who will represent in 2014 and 2015 all CERN staff in the discussions with Management and Member States in the various bodies and committees. Therefore it is important that the Staff Council represents as far as possible the diversity of the CERN population. By construction, the election process with its electoral colleges and two-step voting procedure guarantees that all Departments, even the small ones, and the various staff categories are correctly represented. Figure 1 shows the participation rate in the elections. The average rate is just above 52 %, with ...

  16. Project Temporalities

    DEFF Research Database (Denmark)

    Tryggestad, Kjell; Justesen, Lise; Mouritsen, Jan

    2013-01-01

    Purpose – The purpose of this paper is to explore how animals can become stakeholders in interaction with project management technologies and what happens with project temporalities when new and surprising stakeholders become part of a project and a recognized matter of concern to be taken...... into account. Design/methodology/approach – The paper is based on a qualitative case study of a project in the building industry. The authors use actor-network theory (ANT) to analyze the emergence of animal stakeholders, stakes and temporalities. Findings – The study shows how project temporalities can...... multiply in interaction with project management technologies and how conventional linear conceptions of project time may be contested with the emergence of new non-human stakeholders and temporalities. Research limitations/implications – The study draws on ANT to show how animals can become stakeholders...

  17. Exploring Representativeness and Informativeness for Active Learning.

    Science.gov (United States)

    Du, Bo; Wang, Zengmao; Zhang, Lefei; Zhang, Liangpei; Liu, Wei; Shen, Jialie; Tao, Dacheng

    2017-01-01

    How can we find a general way to choose the most suitable samples for training a classifier? Even with very limited prior information? Active learning, which can be regarded as an iterative optimization procedure, plays a key role to construct a refined training set to improve the classification performance in a variety of applications, such as text analysis, image recognition, social network modeling, etc. Although combining representativeness and informativeness of samples has been proven promising for active sampling, state-of-the-art methods perform well under certain data structures. Then can we find a way to fuse the two active sampling criteria without any assumption on data? This paper proposes a general active learning framework that effectively fuses the two criteria. Inspired by a two-sample discrepancy problem, triple measures are elaborately designed to guarantee that the query samples not only possess the representativeness of the unlabeled data but also reveal the diversity of the labeled data. Any appropriate similarity measure can be employed to construct the triple measures. Meanwhile, an uncertain measure is leveraged to generate the informativeness criterion, which can be carried out in different ways. Rooted in this framework, a practical active learning algorithm is proposed, which exploits a radial basis function together with the estimated probabilities to construct the triple measures and a modified best-versus-second-best strategy to construct the uncertain measure, respectively. Experimental results on benchmark datasets demonstrate that our algorithm consistently achieves superior performance over the state-of-the-art active learning algorithms.

  18. Identifying optimal models to represent biochemical systems.

    Directory of Open Access Journals (Sweden)

    Mochamad Apri

    Full Text Available Biochemical systems involving a high number of components with intricate interactions often lead to complex models containing a large number of parameters. Although a large model could describe in detail the mechanisms that underlie the system, its very large size may hinder us in understanding the key elements of the system. Also in terms of parameter identification, large models are often problematic. Therefore, a reduced model may be preferred to represent the system. Yet, in order to efficaciously replace the large model, the reduced model should have the same ability as the large model to produce reliable predictions for a broad set of testable experimental conditions. We present a novel method to extract an "optimal" reduced model from a large model to represent biochemical systems by combining a reduction method and a model discrimination method. The former assures that the reduced model contains only those components that are important to produce the dynamics observed in given experiments, whereas the latter ensures that the reduced model gives a good prediction for any feasible experimental conditions that are relevant to answer questions at hand. These two techniques are applied iteratively. The method reveals the biological core of a model mathematically, indicating the processes that are likely to be responsible for certain behavior. We demonstrate the algorithm on two realistic model examples. We show that in both cases the core is substantially smaller than the full model.

  19. [Sensitivity of four representative angular cephalometric measures].

    Science.gov (United States)

    Xü, T; Ahn, J; Baumrind, S

    2000-05-01

    Examined the sensitivity of four representative cephalometric angles to the detection of different vectors of craniofacial growth. Landmark coordinate data from a stratified random sample of 48 adolescent subjects were used to calculate conventional values for changes between the pretreatment and end-of-treatment lateral cephalograms. By modifying the end-of-treatment coordinate values appropriately, the angular changes could be recalculated reflecting three hypothetical situations: Case 1. What if there were no downward landmark displacement between timepoints? Case 2. What if there were no forward landmark displacement between timepoints? Case 3. What if there were no Nasion change? These questions were asked for four representative cephalometric angles: SNA, ANB, NAPg and UI-SN. For Case 1, the associations (r) between the baseline and the modified measure for the three angles were very highly significant (P < 0.001) with r2 values no lower than 0.94! For Case 2, however, the associations were much weaker and no r value reached significance. These angular measurements are less sensitive for measuring downward landmark displacement than they are for measuring forward landmark displacement.

  20. Anthropomorphic Networks as Representatives of Global Consciousness

    Directory of Open Access Journals (Sweden)

    Sergii Yahodzinskyi

    2018-02-01

    Full Text Available There has been analyzed a phenomenon of global consciousness, and its cultural and historical, civilizational dimensions have been substantiated. There has been demonstrated that the concept of planetary consciousness, global thinking, noosphere was described for the first time in the philosophy of cosmism. However, in modern conditions ideas of representatives of the naturalistic philosophical direction of cosmism have not lost their heuristic potential. They can be reconsidered in a new fashion within the context of emerging anthropomorphic (human dimension networks. There has been proved that global consciousness is a component of the social and cultural potential of global information networks defining vectors to prospects of humanity progress in the 21st century. Relying on methodology of the structural and functional analysis, the author arrives at a conclusion about global networks obtaining the status of representatives of global consciousness. This is the area of networks where all relevant information is concentrated – from statistical data to scientific and technical information. Access to these data is limited by human abilities and is realized in the form of discrete requests with using heuristic algorithms of information procession. A suggestion is introduced considering the fact that modern society being a self-organized system seeks to gain stable condition. Anthropomorphic networks are means of decreasing social entropy, which is growing as a result of any kind of human intervention into social processes. Thus, for the first time a human is challenged by their intellect, ability to create, discover and control.

  1. How Are Feedbacks Represented in Land Models?

    Directory of Open Access Journals (Sweden)

    Yang Chen

    2016-09-01

    Full Text Available Land systems are characterised by many feedbacks that can result in complex system behaviour. We defined feedbacks as the two-way influences between the land use system and a related system (e.g., climate, soils and markets, both of which are encompassed by the land system. Land models that include feedbacks thus probably more accurately mimic how land systems respond to, e.g., policy or climate change. However, representing feedbacks in land models is a challenge. We reviewed articles incorporating feedbacks into land models and analysed each with predefined indicators. We found that (1 most modelled feedbacks couple land use systems with transport, soil and market systems, while only a few include feedbacks between land use and social systems or climate systems; (2 equation-based land use models that follow a top-down approach prevail; and (3 feedbacks’ effects on system behaviour remain relatively unexplored. We recommend that land system modellers (1 consider feedbacks between land use systems and social systems; (2 adopt (bottom-up approaches suited to incorporating spatial heterogeneity and better representing land use decision-making; and (3 pay more attention to nonlinear system behaviour and its implications for land system management and policy.

  2. May 2013 Council of Chapter Representatives Notes

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2013-05-01

    Full Text Available No abstract available. Article truncated at 150 words. The Council of Chapter Representatives met in conjunction with the ATS meeting in Philadelphia on May 18, 2012.Roll Call. The meeting was called to order at 11 AM. Representatives from Arizona, California, DC Metro, Louisiana, Michigan, New Mexico, New York, Oregon, and Rhode Island were in attendance, and by telephone from Washington.Chapter Updates. Information on chapter activities and a chapter brochure. There are currently 19 active chapters. Most are having annual meetings. Advocacy. Gary Ewart from ATS Government Relations gave a presentation on Washington activities. Highlights included activities on the SGR, a number of air pollution regulations and a letter campaign advocating regulation of cigars. ATS President 2013-14-vision for the coming year. Patrician Finn gave a summary of what she hopes to accomplish over the next year. The theme of her presidency will be health equality. ATS Executive Director-update. Steve Crane gave a positive presentation on the …

  3. Collaborating with consumer and community representatives in health and medical research in Australia: results from an evaluation

    Directory of Open Access Journals (Sweden)

    Bartu Anne E

    2011-05-01

    Full Text Available Abstract Objective To collaborate with consumer and community representatives in the Alcohol and Pregnancy Project from 2006-2008 http://www.ichr.uwa.edu.au/alcoholandpregnancy and evaluate researchers' and consumer and community representatives' perceptions of the process, context and impact of consumer and community participation in the project. Methods We formed two reference groups and sought consumer and community representatives' perspectives on all aspects of the project over a three year period. We developed an evaluation framework and asked consumer and community representatives and researchers to complete a self-administered questionnaire at the end of the project. Results Fifteen researchers (93.8% and seven (53.8% consumer and community representatives completed a questionnaire. Most consumer and community representatives agreed that the process and context measures of their participation had been achieved. Both researchers and consumer and community representatives identified areas for improvement and offered suggestions how these could be improved for future research. Researchers thought consumer and community participation contributed to project outputs and outcomes by enhancing scientific and ethical standards, providing legitimacy and authority, and increasing the project's credibility and participation. They saw it was fundamental to the research process and acknowledged consumer and community representatives for their excellent contribution. Consumer and community representatives were able to directly influence decisions about the research. They thought that consumer and community participation had significant influence on the success of project outputs and outcomes. Conclusions Consumer and community participation is an essential component of good research practice and contributed to the Alcohol and Pregnancy Project by enhancing research processes, outputs and outcomes, and this participation was valued by community and

  4. Collaborating with consumer and community representatives in health and medical research in Australia: results from an evaluation.

    Science.gov (United States)

    Payne, Janet M; D'Antoine, Heather A; France, Kathryn E; McKenzie, Anne E; Henley, Nadine; Bartu, Anne E; Elliott, Elizabeth J; Bower, Carol

    2011-05-14

    To collaborate with consumer and community representatives in the Alcohol and Pregnancy Project from 2006-2008 http://www.ichr.uwa.edu.au/alcoholandpregnancy and evaluate researchers' and consumer and community representatives' perceptions of the process, context and impact of consumer and community participation in the project. We formed two reference groups and sought consumer and community representatives' perspectives on all aspects of the project over a three year period. We developed an evaluation framework and asked consumer and community representatives and researchers to complete a self-administered questionnaire at the end of the project. Fifteen researchers (93.8%) and seven (53.8%) consumer and community representatives completed a questionnaire. Most consumer and community representatives agreed that the process and context measures of their participation had been achieved. Both researchers and consumer and community representatives identified areas for improvement and offered suggestions how these could be improved for future research. Researchers thought consumer and community participation contributed to project outputs and outcomes by enhancing scientific and ethical standards, providing legitimacy and authority, and increasing the project's credibility and participation. They saw it was fundamental to the research process and acknowledged consumer and community representatives for their excellent contribution. Consumer and community representatives were able to directly influence decisions about the research. They thought that consumer and community participation had significant influence on the success of project outputs and outcomes. Consumer and community participation is an essential component of good research practice and contributed to the Alcohol and Pregnancy Project by enhancing research processes, outputs and outcomes, and this participation was valued by community and consumer representatives and researchers. The National Health and

  5. Quantifying Heuristic Bias: Anchoring, Availability, and Representativeness.

    Science.gov (United States)

    Richie, Megan; Josephson, S Andrew

    2018-01-01

    Construct: Authors examined whether a new vignette-based instrument could isolate and quantify heuristic bias. Heuristics are cognitive shortcuts that may introduce bias and contribute to error. There is no standardized instrument available to quantify heuristic bias in clinical decision making, limiting future study of educational interventions designed to improve calibration of medical decisions. This study presents validity data to support a vignette-based instrument quantifying bias due to the anchoring, availability, and representativeness heuristics. Participants completed questionnaires requiring assignment of probabilities to potential outcomes of medical and nonmedical scenarios. The instrument randomly presented scenarios in one of two versions: Version A, encouraging heuristic bias, and Version B, worded neutrally. The primary outcome was the difference in probability judgments for Version A versus Version B scenario options. Of 167 participants recruited, 139 enrolled. Participants assigned significantly higher mean probability values to Version A scenario options (M = 9.56, SD = 3.75) than Version B (M = 8.98, SD = 3.76), t(1801) = 3.27, p = .001. This result remained significant analyzing medical scenarios alone (Version A, M = 9.41, SD = 3.92; Version B, M = 8.86, SD = 4.09), t(1204) = 2.36, p = .02. Analyzing medical scenarios by heuristic revealed a significant difference between Version A and B for availability (Version A, M = 6.52, SD = 3.32; Version B, M = 5.52, SD = 3.05), t(404) = 3.04, p = .003, and representativeness (Version A, M = 11.45, SD = 3.12; Version B, M = 10.67, SD = 3.71), t(396) = 2.28, p = .02, but not anchoring. Stratifying by training level, students maintained a significant difference between Version A and B medical scenarios (Version A, M = 9.83, SD = 3.75; Version B, M = 9.00, SD = 3.98), t(465) = 2.29, p = .02, but not residents or attendings. Stratifying by heuristic and training level, availability maintained

  6. Picturing and modelling catchments by representative hillslopes

    Science.gov (United States)

    Loritz, Ralf; Hassler, Sibylle; Jackisch, Conrad; Zehe, Erwin

    2016-04-01

    Hydrological modelling studies often start with a qualitative sketch of the hydrological processes of a catchment. These so-called perceptual models are often pictured as hillslopes and are generalizations displaying only the dominant and relevant processes of a catchment or hillslope. The problem with these models is that they are prone to become too much predetermined by the designer's background and experience. Moreover it is difficult to know if that picture is correct and contains enough complexity to represent the system under study. Nevertheless, because of their qualitative form, perceptual models are easy to understand and can be an excellent tool for multidisciplinary exchange between researchers with different backgrounds, helping to identify the dominant structures and processes in a catchment. In our study we explore whether a perceptual model built upon an intensive field campaign may serve as a blueprint for setting up representative hillslopes in a hydrological model to reproduce the functioning of two distinctly different catchments. We use a physically-based 2D hillslope model which has proven capable to be driven by measured soil-hydrological parameters. A key asset of our approach is that the model structure itself remains a picture of the perceptual model, which is benchmarked against a) geo-physical images of the subsurface and b) observed dynamics of discharge, distributed state variables and fluxes (soil moisture, matric potential and sap flow). Within this approach we are able to set up two behavioral model structures which allow the simulation of the most important hydrological fluxes and state variables in good accordance with available observations within the 19.4 km2 large Colpach catchment and the 4.5 km2 large Wollefsbach catchment in Luxembourg without the necessity of calibration. This corroborates, contrary to the widespread opinion, that a) lower mesoscale catchments may be modelled by representative hillslopes and b) physically

  7. Using resource graphs to represent conceptual change

    Directory of Open Access Journals (Sweden)

    Michael C. Wittmann

    2006-08-01

    Full Text Available We introduce resource graphs, a representation of linked ideas used when reasoning about specific contexts in physics. Our model is consistent with previous descriptions of coordination classes and resources. It represents mesoscopic scales that are neither knowledge-in-pieces nor large-scale concepts. We use resource graphs to describe several forms of conceptual change: incremental, cascade, wholesale, and dual construction. For each, we give evidence from the physics education research literature to show examples of each form of conceptual change. Where possible, we compare our representation to models used by other researchers. Building on our representation, we analyze another form of conceptual change, differentiation, and suggest several experimental studies that would help understand the differences between reform-based curricula.

  8. STATISTICAL MODELS OF REPRESENTING INTELLECTUAL CAPITAL

    Directory of Open Access Journals (Sweden)

    Andreea Feraru

    2016-06-01

    Full Text Available This article entitled Statistical Models of Representing Intellectual Capital approaches and analyses the concept of intellectual capital, as well as the main models which can support enterprisers/managers in evaluating and quantifying the advantages of intellectual capital. Most authors examine intellectual capital from a static perspective and focus on the development of its various evaluation models. In this chapter we surveyed the classical static models: Sveiby, Edvisson, Balanced Scorecard, as well as the canonical model of intellectual capital. Among the group of static models for evaluating organisational intellectual capital the canonical model stands out. This model enables the structuring of organisational intellectual capital in: human capital, structural capital and relational capital. Although the model is widely spread, it is a static one and can thus create a series of errors in the process of evaluation, because all the three entities mentioned above are not independent from the viewpoint of their contents, as any logic of structuring complex entities requires.

  9. Towards a representative periphytic diatom sample

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available The need to acquire a representative periphytic diatom sample for river water quality monitoring has been recognised in the development of existing diatom indices, important in the development and employment of diatom monitoring tools for the Water Framework Directive. In this study, a nested design with replication is employed to investigate the magnitude of variation in diatom biomass, composition and Trophic Diatom Index at varying scales within a small chalk river. The study shows that the use of artificial substrates may not result in diatom communities that are typical of the surrounding natural substrates. Periphytic diatom biomass and composition varies between artificial and natural substrates, riffles and glides and between two stretches of the river channel. The study also highlights the existence of high variation in diatom frustule frequency and biovolume at the individual replicate scale which may have implications for the use of diatoms in routine monitoring.

  10. Project control - the next generation

    International Nuclear Information System (INIS)

    Iorii, V.F.; McKinnon, B.L.

    1993-01-01

    The Yucca Mountain Site Characterization Project (YMP) is the U.S. Department of Energy's (DOE) second largest Major System Acquisition Project. We have developed an integrated planning and control system (called PACS) that we believe represents the 'Next Generation' in project control. PACS integrates technical scope, cost, and schedule information for over 50 participating organizations and produces performances measurement reports for science and engineering managers at all levels. Our 'Next Generation' project control too, PACS, has been found to be in compliance with the new DOE Project Control System Guidelines. Additionally, the nuclear utility oversight group of the Edison Electric Institute has suggested PACS be used as a model for other civilian radioactive waste management projects. A 'Next Generation' project control tool will be necessary to do science in the 21st century

  11. LEX Project

    DEFF Research Database (Denmark)

    Damkilde, Lars; Larsen, Torben J.; Walbjørn, Jacob

    This document is aimed at helping all parties involved in the LEX project to get a common understanding of words, process, levels and the overall concept.......This document is aimed at helping all parties involved in the LEX project to get a common understanding of words, process, levels and the overall concept....

  12. OMEGA project

    International Nuclear Information System (INIS)

    Shibuya, E.H.

    1989-01-01

    The OMEGA - Observation of Multiple particle production, Exotic Interactions and Gamma-ray Air Shower-project is presented. The project try to associate photosensitive detectors from experiences of hadronic interactions with electronic detectors used by experiences that investigate extensive atmospheric showers. (M.C.K.)

  13. Research Planning and Evaluation Project

    International Nuclear Information System (INIS)

    Song, Seunghyun; Kim, Doyang; Ryu, Byunghoon; Lim, Chaeyoung; Song, Leeyoung; Lee, Youngchul; Han, Changsun; Kim, Hackchoon

    2011-12-01

    - To activate R and D through a systematic and impartial evaluation by using information on efficient distribution of research resource, setting project priorities, and measuring achievement against goals produced after research on planning and evaluation system for the government-funded project for KAERI was conducted. - Nuclear R and D project is the representative national R and D project which has been implemented in Korea. For the sustainable development of nuclear energy which supplies about 40% of total electricity generation and the enhancement of it innovative ability in the future, a systematic and efficient strategy in the planning stage is required

  14. Twenty-sixth general conference meeting of representatives of RCA member states. Report

    International Nuclear Information System (INIS)

    1997-10-01

    The meeting discussed the following issues: RCA Annual Report 1996; Report of the 19th RCA Working Group Meeting, Yangon Myanmar, 10-14 March 1997; RCA in the next 25 years; Development finance and the RCA; locating a senior RCA representative in the region; RCA guidelines and operating rules; TCDC activities; terminal tripartite review meeting on UNDP/RCA/IAEA project; status of new joint UNDP/RCA/IAEA project; options for the new joint project; RCA activities and budget in 1997 and 1998; reformulation and health care project; RCA proposed programme for 1999-2000; country statements; extension of RCA agreement; RCA 25th anniversary; venue and date of the 20th regular meeting of national RCA representatives

  15. Twenty-sixth general conference meeting of representatives of RCA member states. Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    The meeting discussed the following issues: RCA Annual Report 1996; Report of the 19th RCA Working Group Meeting, Yangon Myanmar, 10-14 March 1997; RCA in the next 25 years; Development finance and the RCA; locating a senior RCA representative in the region; RCA guidelines and operating rules; TCDC activities; terminal tripartite review meeting on UNDP/RCA/IAEA project; status of new joint UNDP/RCA/IAEA project; options for the new joint project; RCA activities and budget in 1997 and 1998; reformulation and health care project; RCA proposed programme for 1999-2000; country statements; extension of RCA agreement; RCA 25th anniversary; venue and date of the 20th regular meeting of national RCA representatives.

  16. Recent activities of the Seismology Division Early Career Representative(s)

    Science.gov (United States)

    Agius, Matthew; Van Noten, Koen; Ermert, Laura; Mai, P. Martin; Krawczyk, CharLotte

    2016-04-01

    The European Geosciences Union is a bottom-up-organisation, in which its members are represented by their respective scientific divisions, committees and council. In recent years, EGU has embarked on a mission to reach out for its numerous 'younger' members by giving awards to outstanding young scientists and the setting up of Early Career Scientists (ECS) representatives. The division representative's role is to engage in discussions that concern students and early career scientists. Several meetings between all the division representatives are held throughout the year to discuss ideas and Union-wide issues. One important impact ECS representatives have had on EGU is the increased number of short courses and workshops run by ECS during the annual General Assembly. Another important contribution of ECS representatives was redefining 'Young Scientist' to 'Early Career Scientist', which avoids discrimination due to age. Since 2014, the Seismology Division has its own ECS representative. In an effort to more effectively reach out for young seismologists, a blog and a social media page dedicated to seismology have been set up online. With this dedicated blog, we'd like to give more depth to the average browsing experience by enabling young researchers to explore various seismology topics in one place while making the field more exciting and accessible to the broader community. These pages are used to promote the latest research especially of young seismologists and to share interesting seismo-news. Over the months the pages proved to be popular, with hundreds of views every week and an increased number of followers. An online survey was conducted to learn more about the activities and needs of early career seismologists. We present the results from this survey, and the work that has been carried out over the last two years, including detail of what has been achieved so far, and what we would like the ECS representation for Seismology to achieve. Young seismologists are

  17. Why does project planning fail

    International Nuclear Information System (INIS)

    Foley, M.; Luciano, G.

    1991-01-01

    The technology of project controls have become increasingly sophisticated. Some say that the technological advancements of the Nineteen-Eighties represented a maturation of project control tools. Others say that the advancements were merely bells and whistles that added little or nothing to the project management process. Above it all, as we enter the Nineties, there is a popular outcry to get back to the basics of planning. The genesis of this outcry is the sobering impact of significant cost overruns and schedule extensions, even on projects that have employed the most advanced project control tools and systems. This paper examines the merits of taking a strategic approach to the project planning process. Within that context, there are basic goals of planning which are enduring through the life cycle of the project. Key reasons for failure and inability to achieve the goals of project planning are explained. By examining the goals of project planning and the reasons for failure, insight is provided into the role of project controls specialists and sophisticated project control tools in meeting the challenges of complex project management in the 1990's

  18. Watchdog Project

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Rhett [Schweitzer Engineering Laboratories, Inc., Pullman, WA (United States); Campbell, Jack [CenterPoint Energy Houston Electric, TX (United States); Hadley, Mark [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-12-30

    The Watchdog Project completed 100% of the project Statement of Project Objective (SOPO). The Watchdog project was a very aggressive project looking to accomplish commercialization of technology that had never been commercialized, as a result it took six years to complete not the original three that were planned. No additional federal funds were requested from the original proposal and SEL contributed the additional cost share required to complete the project. The result of the Watchdog Project is the world’s first industrial rated Software Defined Network (SDN) switch commercially available. This technology achieved the SOPOO and DOE Roadmap goals to have strong network access control, improve reliability and network performance, and give the asset owner the ability to minimize attack surface before and during an attack. The Watchdog project is an alliance between CenterPoint Energy Houston Electric, Pacific Northwest National Laboratories (PNNL), and Schweitzer Engineering Laboratories, Inc. (SEL). SEL is the world’s leader in microprocessor-based electronic equipment for protecting electric power systems. PNNL performs basic and applied research to deliver energy, environmental, and national security for our nation. CenterPoint Energy is the third largest publicly traded natural gas delivery company in the U.S and third largest combined electricity and natural gas delivery company. The Watchdog Project efforts were combined with the SDN Project efforts to produce the entire SDN system solution for the critical infrastructure. The Watchdog project addresses Topic Area of Interest 5: Secure Communications, for the DEFOA- 0000359 by protecting the control system local area network itself and the communications coming from and going to the electronic devices on the local network. Local area networks usually are not routed and have little or no filtering capabilities. Combine this with the fact control system protocols are designed with inherent trust the control

  19. What does self rated mental health represent

    Directory of Open Access Journals (Sweden)

    Daphna Levinson

    2014-12-01

    Full Text Available Background. Unlike the widely used self rated health, the self rated mental health was found unsuitable as a proxy for mental illness. This paper analyses the relationships between the self ratings of physical health, mental health and overall health, and their association of with the objective indicators for physical and mental health. Design and methods. The study is a secondary analysis of data from a nationwide representative sample of the non-institutionalized adult residents of Israel in 2003 that was collected via computer-assisted personal interview methods [n=4859].Results. The self rated physical health and the self rated mental health were strongly related to each other yet the self rated mental health was not related to chronic physical conditions and the self rated physical health was not related to mental disorders. In a multiple logistic regression analysis, those with positive self rated mental health had 93 times the odds of reporting positive overall health whereas those with positive self rated physical health had 40 times the odds of reporting positive overall health. Conclusions. The self rating of mental health presents a qualitatively different dimension from mental illness. The self rated mental health is two times more important than the self rated physical health in predicting the self rated overall health

  20. The Two Sides of the Representative Coin

    Directory of Open Access Journals (Sweden)

    Keith Sutherland

    2011-12-01

    Full Text Available In Federalist 10 James Madison drew a functional distinction between “parties” (advocates for factional interests and “judgment” (decision-making for the public good and warned of the corrupting effect of combining both functions in a “single body of men.” This paper argues that one way of overcoming “Madisonian corruption” would be by restricting political parties to an advocacy role, reserving the judgment function to an allotted (randomly-selected microcosm of the whole citizenry, who would determine the outcome of parliamentary debates by secret ballot—a division of labour suggested by James Fishkin’s experiments in deliberative polling. The paper then defends this radical constitutional proposal against Bernard Manin’s (1997 claim that an allotted microcosm could not possibly fulfil the “consent” requirement of Natural Right theory. Not only does the proposal challenge Manin’s thesis, but a 28th Amendment implementing it would finally reconcile the competing visions that have bedevilled representative democracy since the Constitutional Convention of 1787.

  1. The Colibri Project

    DEFF Research Database (Denmark)

    Lopez, Jose Manuel Guterrez Lopez; Frick, Jan; Kirikova, Marite

    2015-01-01

    Colibri (Collaboration and Innovation for Better, Personalized and IT-Supported Teaching) is a three year project co-funded by the Erasmus + Strategic Partnership, starting in 2014. The project is being carried out by seven academic, two industrial, and one governmental organisation partners from...... eight different countries [1]. The main objective of the project is enhancing the quality and relevance of the learning offer in education by developing and systematically testing new and innovative approaches, and by supporting the dissemination and spreading of best practices. This is in the focus...... course on Future Internet Opportunities is part of the Living Lab, followed by 28 students and given by more than 10 different teachers. Both the teachers and the students represent different fields within computer science, electrical engineering, telecommunications, business informatics, management...

  2. IPAD project overview

    Science.gov (United States)

    Fulton, R. E.

    1980-01-01

    To respond to national needs for improved productivity in engineering design and manufacturing, a NASA supported joint industry/government project is underway denoted Integrated Programs for Aerospace-Vehicle Design (IPAD). The objective is to improve engineering productivity through better use of computer technology. It focuses on development of technology and associated software for integrated company-wide management of engineering information. The project has been underway since 1976 under the guidance of an Industry Technical Advisory Board (ITAB) composed of representatives of major engineering and computer companies and in close collaboration with the Air Force Integrated Computer-Aided Manufacturing (ICAM) program. Results to date on the IPAD project include an in-depth documentation of a representative design process for a large engineering project, the definition and design of computer-aided design software needed to support that process, and the release of prototype software to integrate selected design functions. Ongoing work concentrates on development of prototype software to manage engineering information, and initial software is nearing release.

  3. Overview of research in the ADVANTAGE project

    DEFF Research Database (Denmark)

    Angjelichinoski, Marko; Cosovic, Mirsad; Kalalas, Charalampos

    2016-01-01

    The European Marie Curie Project ADVANTAGE (Advanced Communications and Information processing in smart grid systems) was launched in 2014. It represents a major inter-disciplinary research project into the topic of Smart Grid technology. A key aspect of the project is to bring together and train...

  4. Freedom Project

    Directory of Open Access Journals (Sweden)

    Alejandra Suarez

    2014-02-01

    Full Text Available Freedom Project trains prisoners in nonviolent communication and meditation. Two complementary studies of its effects are reported in this article. The first study is correlational; we found decreased recidivism rates among prisoners trained by Freedom Project compared with recidivism rates in Washington state. The second study compared trained prisoners with a matched-pair control group and found improvement in self-reported anger, self-compassion, and certain forms of mindfulness among the trained group. Ratings of role-plays simulating difficult interactions show increased social skills among the group trained by Freedom Project than in the matched controls.

  5. Musculoskeletal symptoms in pharmaceutical sales representatives.

    Science.gov (United States)

    Sang, Katherine; Gyi, Diane; Haslam, Cheryl

    2010-03-01

    Musculoskeletal disorders (MSDs) are a leading cause of work-related ill health. Existing literature indicates that pharmaceutical sales representatives (PSRs) report a high prevalence of MSDs, possibly exacerbated by the nature of work (prolonged driving and manual handling). In addition, they experience difficulty in accessing occupational health services. To assess the prevalence of musculoskeletal symptoms and associated risk factors among PSRs in order to assist their occupational health management through raising risk awareness. A self-completed questionnaire distributed to 205 PSRs within a UK pharmaceutical company was used to assess the prevalence of musculoskeletal symptoms, psychosocial factors, work tasks undertaken and company car use. To assist understanding of work tasks and organizational factors, semi-structured interviews were undertaken with a sample of 12 key personnel. The questionnaire response rate was 68%. PSRs reported high mileage and 100% reported working from the car in a typical day. Forty-seven per cent reported both manual handling for > or = 4 h/day and 'often' or 'sometimes' working from the car. Fifty-seven per cent reported low back symptoms in the last 12 months. Interview data revealed issues relating to car choice, storage in the boot and working from the car, which should be considered when developing priorities for preventive management of MSDs. Musculoskeletal symptoms appear to be a problem for PSRs, with risk factors reported as prolonged driving, sitting in the car, working from the car and manual handling. Interventions to facilitate their occupational health management should focus on raising awareness of the risks of prolonged driving and working from the car.

  6. Representativeness in corpora of literary texts: introducing the C18P project

    Directory of Open Access Journals (Sweden)

    Gemeinböck, Iris

    2016-07-01

    Full Text Available Currently there are very few specialised corpora of literary texts that are tailored to the needs of literary critics who are interested in corpus stylistic analyses of prose fiction. Many existing corpora including literary texts were compiled for linguistic research interests and are often unsuitable for corpus stylistic purposes. The paper addresses three of the main problems: the absence of labelling of the texts for literary genre, the use of extracts, and the prevalence of linguistic periodisation schemes. C18P is a corpus of prose fiction designed specifically to address these issues. It traces the early development of the novel from 1700 up until the Victorian era. It can, for instance, be used for an analysis of the characteristic linguistic features of individual literary genres and forms. The following paper introduces the design of the corpus as well as some of its potential uses.

  7. EBFA project

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    An engineering project office was established during the fall of 1976 to manage and coordinate all of the activities of the Electron Beam Fusion Project. The goal of the project is to develop the Electron Beam Fusion Accelerator (EBFA) and its supporting systems, and integrate these systems into the new Electron Beam Fusion Facility (EBFF). Supporting systems for EBFA include a control/monitor system, a data acquistion/automatic data processing system, the liquid transfer systems, the insulating gas transfer systems, etc. Engineers and technicians were assigned to the project office to carry out the engineering design, initiate procurement, monitor the fabrication, perform the assembly and to assist the pulsed power research group in the activation of the EBFA

  8. Project Reptile!

    Science.gov (United States)

    Diffily, Deborah

    2001-01-01

    Integrating curriculum is important in helping children make connections within and among areas. Presents a class project for kindergarten children which came out of the students' interests and desire to build a reptile exhibit. (ASK)

  9. Project Soar.

    Science.gov (United States)

    Austin, Marion

    1982-01-01

    Project Soar, a Saturday enrichment program for gifted students (6-14 years old), allows students to work intensively in a single area of interest. Examples are cited of students' work in crewel embroidery, creative writing, and biochemistry. (CL)

  10. EUROFANCOLEN Project

    International Nuclear Information System (INIS)

    Bueren, J. A.

    2014-01-01

    The first follow-up report of European Project EUROFANCOLEN, the purpose of which is to develop a gene therapy clinical trial to resolve bone marrow failure in patients with a genetic disease known as Fanconi anemia (FA), was sent to the European Commission in September. The main objective of project EUROFANCOLEN is to develop a gene therapy trial for patients with Fanconi anemia Type A (FA-A), which affects 80% of the patients with FA in Spain. (Author)

  11. Project Management

    DEFF Research Database (Denmark)

    Kampf, Constance

    2009-01-01

    In this video Associate Professor Constance Kampf talks about the importance project management. Not only as a tool in implementation, but also as a way of thinking, and as something that needs to be considered from idea conception......In this video Associate Professor Constance Kampf talks about the importance project management. Not only as a tool in implementation, but also as a way of thinking, and as something that needs to be considered from idea conception...

  12. HOW TO REPRESENT THE GENETIC CODE?

    Directory of Open Access Journals (Sweden)

    N.S. Santos-Magalhães

    2004-05-01

    Full Text Available The advent of molecular genetic comprises a true revolution of far-reaching consequences for human-kind, which evolved into a specialized branch of the modern-day Biochemistry. The analysis of specicgenomic information are gaining wide-ranging interest because of their signicance to the early diag-nosis of disease, and the discovery of modern drugs. In order to take advantage of a wide assortmentof signal processing (SP algorithms, the primary step of modern genomic SP involves convertingsymbolic-DNA sequences into complex-valued signals. How to represent the genetic code? Despitebeing extensively known, the DNA mapping into proteins is one of the relevant discoveries of genetics.The genetic code (GC is revisited in this work, addressing other descriptions for it, which can beworthy for genomic SP. Three original representations are discussed. The inner-to-outer map buildson the unbalanced role of nucleotides of a codon. A two-dimensional-Gray genetic representationis oered as a structured map that can help interpreting DNA spectrograms or scalograms. Theseare among the powerful visual tools for genome analysis, which depends on the choice of the geneticmapping. Finally, the world-chart for the GC is investigated. Evoking the cyclic structure of thegenetic mapping, it can be folded joining the left-right borders, and the top-bottom frontiers. As aresult, the GC can be drawn on the surface of a sphere resembling a world-map. Eight parallels oflatitude are required (four in each hemisphere as well as four meridians of longitude associated tofour corresponding anti-meridians. The tropic circles have 11.25o, 33.75o, 56.25o, and 78.5o (Northand South. Starting from an arbitrary Greenwich meridian, the meridians of longitude can be plottedat 22.5o, 67.5o, 112.5o, and 157.5o (East and West. Each triplet is assigned to a single point on thesurface that we named Nirenberg-Kohamas Earth. Despite being valuable, usual representations forthe GC can be

  13. Application to Representative Structures. Other Representative Structures: Mutsu-Ogawara, Niigata East and West

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Burcharth, Hans F.

    1999-01-01

    Reliability analyses are performed for three Japanese vertical wall breakwaters in this chapter. Only the geotechnical failure modes described in chapter 3 are investigated. For none of the breakwaters detailed data are available for the wave climate and for the soil conditions. Therefore represe...

  14. Pedagogy of stereographic projection

    Science.gov (United States)

    Blenkinsop, Tom

    1999-05-01

    Three sorts of problem are encountered by students learning stereographic projection. Lack of familiarity with compass directions and with the specification of planar and linear orientations is the most fundamental problem. The second problem is one of poor visualisation which prohibits the correct understanding of the principles and practice of projection, although students can sometimes perform remarkably well on certain exercises without this understanding. A third problem is a lack of interest or appreciation of the usefulness of the technique. A solution to the first problem is to provide a thorough grounding in compass directions, and concepts of strike, dip, dip direction, plunge and plunge bearing immediately before teaching stereographic projection. Visual aids, such as a transparent hemisphere to represent half of the projection sphere, and a large stereonet, are helpful for visualisation. Estimation and sketching exercises help to develop an understanding of the geometry of projection. Computer-aided teaching and plotting is recommended after an introduction to manual techniques. Interest can be stimulated through the use of exercises based on real geological maps.

  15. Project mobilisation

    International Nuclear Information System (INIS)

    Clark, J.; Limbrick, A.

    1996-01-01

    This paper identifies and reviews the issues to be addressed and the procedures to be followed during the mobilisation of projects using LFG as an energy source. Knowledge of the procedures involved in project mobilisation, their sequence and probable timescales, is essential for efficient project management. It is assumed that the majority of projects will be situated on existing, licensed landfill sites and, in addition to complying with the relevant conditions of the waste management licence and original planning consent, any proposed developments on the site will require a separate planning consent. Experience in the UK indicates that obtaining planning permission rarely constitutes a barrier to the development of schemes for the utilisation of LFG. Even so, an appreciation of the applicable environmental and planning legislation is essential as this will enable the developer to recognise the main concerns of the relevant planning authority at an early stage of the project, resulting in the preparation of an informed and well-structured application for planning permission. For a LFG utilisation scheme on an existing landfill site, the need to carry out an environmental assessment (EA) as part of the application for planning permission will, in vitually all cases, be discretionary. Even if not deemed necessary by the planning authority, an EA is a useful tool at the planning application stage, to identify and address potential problems and to support discussions with bodies such as the Environment Agency, from whom consents or authorisations may be required. Carrying out an EA can thus provide for more cost-effective project development and enhanced environmental protection. Typically, the principal contractual arrangements, such as the purchase of gas or the sale of electricity, will have been established before the project mobilisation phase. However, there are many other contractural arrangements that must be established, and consents and permits that may be

  16. Changes in water availability in the Upper Blue Nile basin under the representative concentration pathways scenario

    NARCIS (Netherlands)

    Haile, Alemseged Tamiru; Akawka, Ashenafi Lekasa; Berhanu, Beza; Rientjes, T.H.M.

    2017-01-01

    Climatic and hydrological changes will likely be intensified in the Upper Blue Nile (UBN) basin by the effects of global warming. The extent of such effects for representative concentration pathways (RCP) climate scenarios is unknown. We evaluated projected changes in rainfall and evapotranspiration

  17. Registration Appointment and Services for Representatives Management Information

    Data.gov (United States)

    Social Security Administration — A new internet/intranet application that collects all representative information and establishes the relationship between the claimant and the representative. Allow...

  18. Do 16 Polycyclic Aromatic Hydrocarbons Represent PAH Air Toxicity?

    Science.gov (United States)

    Samburova, Vera; Zielinska, Barbara; Khlystov, Andrey

    2017-08-15

    Estimation of carcinogenic potency based on analysis of 16 polycyclic aromatic hydrocarbons (PAHs) ranked by U.S. Environmental Protection Agency (EPA) is the most popular approach within scientific and environmental air quality management communities. The majority of PAH monitoring projects have been focused on particle-bound PAHs, ignoring the contribution of gas-phase PAHs to the toxicity of PAH mixtures in air samples. In this study, we analyzed the results of 13 projects in which 88 PAHs in both gas and particle phases were collected from different sources (biomass burning, mining operation, and vehicle emissions), as well as in urban air. The aim was to investigate whether 16 particle-bound U.S. EPA priority PAHs adequately represented health risks of inhalation exposure to atmospheric PAH mixtures. PAH concentrations were converted to benzo(a)pyrene-equivalent (BaPeq) toxicity using the toxic equivalency factor (TEF) approach. TEFs of PAH compounds for which such data is not available were estimated using TEFs of close isomers. Total BaPeq toxicities (∑ 88 BaPeq) of gas- and particle-phase PAHs were compared with BaPeq toxicities calculated for the 16 particle-phase EPA PAH (∑ 16EPA BaPeq). The results showed that 16 EPA particle-bound PAHs underrepresented the carcinogenic potency on average by 85.6% relative to the total (gas and particle) BaPeq toxicity of 88 PAHs. Gas-phase PAHs, like methylnaphthalenes, may contribute up to 30% of ∑ 88 BaPeq. Accounting for other individual non-EPA PAHs (i.e., benzo(e)pyrene) and gas-phase PAHs (i.e., naphthalene, 1- and 2-methylnaphthalene) will make the risk assessment of PAH-containing air samples significantly more accurate.

  19. An Anthology as a Representative Genre in Contemporary Ukrainian Literature

    Directory of Open Access Journals (Sweden)

    Olena Haleta

    2013-12-01

    Full Text Available In this article is analyzed a history and functions of an anthology in a modern Ukrainian literature from the last quarter of the 19th c. to the beginning of the 21st. An anthology is treated as a literary and anthropological project which is characterized by recasting of original materials and specific politics of its re-arangement. It proposes a new cultural value hierarchy, defines a literary field and the rules of its organization. As a form of literary self-representation an anthology participates in a process of forming a literary tradition and canon, its diversification up to the emergence of anti-canon; it intensifies a work of cultural memory, represents new literary genres and styles and also indicates an appearance of diaspora as a model of cultural citizenship. Numerous anthological projects also stress spacial, performative, subjective, gender, erotical, somatic, and oneirological aspects of creative writing; they rethink a very nature of literature as a creative experiment and as a social action in a context of mass culture and new media development. This allows us to consider the literary anthology as a way of a literary self-reflection and as a separate meta-genre in modern Ukrainian literature. The main genre-defining anthological qualities are such as selectivity, double methonimity, integrity and an ability to create new cultural values. The history of anthology as a specific meta-genre helps us to understand the general pecularities of modenr and postmodern literature, its structure and principles of development, its key problems and challanges and also its the most important achievements.

  20. Projective mapping

    DEFF Research Database (Denmark)

    Dehlholm, Christian; Brockhoff, Per B.; Bredie, Wender Laurentius Petrus

    2012-01-01

    by the practical testing environment. As a result of the changes, a reasonable assumption would be to question the consequences caused by the variations in method procedures. Here, the aim is to highlight the proven or hypothetic consequences of variations of Projective Mapping. Presented variations will include...... instructions and influence heavily the product placements and the descriptive vocabulary (Dehlholm et.al., 2012b). The type of assessors performing the method influences results with an extra aspect in Projective Mapping compared to more analytical tests, as the given spontaneous perceptions are much dependent......Projective Mapping (Risvik et.al., 1994) and its Napping (Pagès, 2003) variations have become increasingly popular in the sensory field for rapid collection of spontaneous product perceptions. It has been applied in variations which sometimes are caused by the purpose of the analysis and sometimes...

  1. Isotopes Project

    International Nuclear Information System (INIS)

    Dairiki, J.M.; Browne, E.; Firestone, R.B.; Lederer, C.M.; Shirley, V.S.

    1984-01-01

    The Isotopes Project compiles and evaluates nuclear structure and decay data and disseminates these data to the scientific community. From 1940-1978 the Project had as its main objective the production of the Table of Isotopes. Since publication of the seventh (and last) edition in 1978, the group now coordinates its nuclear data evaluation efforts with those of other data centers via national and international nuclear data networks. The group is currently responsible for the evaluation of mass chains A = 167-194. All evaluated data are entered into the International Evaluated Nuclear Structure Data File (ENSDF) and are published in Nuclear Data Sheets. In addition to the evaluation effort, the Isotopes Project is responsible for production of the Radioactivity Handbook

  2. LLAMA Project

    Science.gov (United States)

    Arnal, E. M.; Abraham, Z.; Giménez de Castro, G.; de Gouveia dal Pino, E. M.; Larrarte, J. J.; Lepine, J.; Morras, R.; Viramonte, J.

    2014-10-01

    The project LLAMA, acronym of Long Latin American Millimetre Array is very briefly described in this paper. This project is a joint scientific and technological undertaking of Argentina and Brazil on the basis of an equal investment share, whose mail goal is both to install and to operate an observing facility capable of exploring the Universe at millimetre and sub/millimetre wavelengths. This facility will be erected in the argentinean province of Salta, in a site located at 4830m above sea level.

  3. Waste Management Project Contingency Analysis

    International Nuclear Information System (INIS)

    Edward L. Parsons, Jr.

    1999-01-01

    The purpose of this report is to provide the office of Waste Management (WM) with recommended contingency calculation procedures for typical WM projects. Typical projects were defined as conventional construction-type activities that use innovative elements when necessary to meet the project objectives. Projects involve treatment, storage, and disposal of low level, mixed low level, hazardous, transuranic, and high level waste. Cost contingencies are an essential part of Total Cost Management. A contingency is an amount added to a cost estimate to compensate for unexpected expenses resulting from incomplete design, unforeseen and unpredictable conditions, or uncertainties in the project scope (DOE 1994, AACE 1998). Contingency allowances are expressed as percentages of estimated cost and improve cost estimates by accounting for uncertainties. The contingency allowance is large at the beginning of a project because there are more uncertainties, but as a project develops, the allowance shrinks to adjust for costs already incurred. Ideally, the total estimated cost remains the same throughout a project. Project contingency reflects the degree of uncertainty caused by lack of project definition, and process contingency reflects the degree of uncertainty caused by use of new technology. Different cost estimation methods were reviewed and compared with respect to terminology, accuracy, and Cost Guide standards. The Association for the Advancement of Cost Engineering (AACE) methods for cost estimation were selected to represent best industry practice. AACE methodology for contingency analysis can be readily applied to WM Projects, accounts for uncertainties associated with different stages of a project, and considers both project and process contingencies and the stage of technical readiness. As recommended, AACE contingency allowances taper off linearly as a project nears completion

  4. Heterogeneous researchers in a two-sector representative consumer economy

    Directory of Open Access Journals (Sweden)

    Orlando Gomes

    2006-06-01

    Full Text Available Research activities have uncertain outcomes. The question asked in this paper is whether or not this uncertainty can be a central piece on the explanation of long run consumption growth paths. More specifically, we inquire how the existence of different research projects, with different degrees of uncertainty, contributes to unpredictable consumption growth paths. The proposed scenario is a two-sector representative consumer model with researchers that invest in different innovation projects. There is heterogeneity in terms of risk associated to research programs (researchers invest in projects with the same expected outcome but different volatility. This difference in volatility, combined with an adaptive learning - bounded rationality rule, implies an aggregate index of technology and a consumption growth rate that do not present a predictable pattern over time.As actividades de investigação produzem resultados incertos. A questão colocada neste artigo é se esta incerteza pode ser uma peça central na explicação das trajectórias de crescimento do consumo no longo prazo. Mais especificamente, pergunta-se como a existência de diferentes projectos de investigação, com diferentes graus de incerteza associados, contribui para trajectórias de crescimento do consumo que não são passíveis de previsão. O cenário proposto é um modelo de consumidor representativo de dois sectores com investigadores que investem em diferentes projectos de inovação. Existe heterogeneidade ao nível do risco associado aos programas de investigação (os investigadores investem em projectos com o mesmo resultado esperado mas diferente volatilidade. A diferença na volatilidade, combinada com uma regra de aprendizagem adaptativa - racionalidade limitada, implica um índice agregado de tecnologia e uma taxa de crescimento do consumo que não apresentam um padrão previsível ao longo do tempo.

  5. Project Avatar

    DEFF Research Database (Denmark)

    Juhlin, Jonas Alastair

    'Project Avatar' tager udgangspunkt i den efterretningsdisciplin, der kaldes Open Source Intelligence og indebærer al den information, som ligger frit tilgængeligt i åbne kilder. Med udbredelsen af sociale medier åbners der op for helt nye typer af informationskilder. Spørgsmålet er; hvor nyttig er...

  6. Project Baltia

    Index Scriptorium Estoniae

    2007-01-01

    Uus arhitektuuriajakiri "Project Baltia" tutvustab Baltimaade, Soome ja Peterburi regiooni arhitektuuri, linnaehitust ja disaini. Ilmub neli korda aastas inglise- ja venekeelsena. Väljaandja: kirjastus Balticum Peterburis koostöös Amsterdami ja Moskva kirjastusega A-Fond. Peatoimetaja Vladimir Frolov

  7. Tedese Project

    Science.gov (United States)

    Buforn, E.; Davila, J. Martin; Bock, G.; Pazos, A.; Udias, A.; Hanka, W.

    The TEDESE (Terremotos y Deformacion Cortical en el Sur de España) project is a joint project of the Universidad Complutense de Madrid (UCM) and Real Instituto y Observatorio de la Armada de San Fernando, Cadiz (ROA) supported by the Spanish Ministerio de Ciencia y Tecnologia with the participation of the GeoforschungZen- trum, Potsdam (GFZ). The aim is to carry out a study of the characteristics of the oc- currence and mechanism of earthquakes together with measurements of crustal struc- ture and deformations in order to obtain an integrated evaluation of seismic risk in southern Spain from. As part of this project a temporal network of 10 broad-band seismological stations, which will complete those already existing in the zone, have been installed in southern Spain and northern Africa for one year beginning in October 2001. The objectives of the project are the study in detail of the focal mechanisms of earthquakes in this area, of structural in crust and upper mantle, of seismic anisotropy in crust and mantle as indicator for tectonic deformation processed and the measure- ments of crustal deformations using techniques with permanent GPS and SLR stations and temporary GPS surveys. From these studies, seismotectonic models and maps will be elaborated and seismic risk in the zone will be evaluated.

  8. Project Boomerang

    Science.gov (United States)

    King, Allen L.

    1975-01-01

    Describes an experimental project on boomerangs designed for an undergraduate course in classical mechanics. The students designed and made their own boomerangs, devised their own procedures, and carried out suitable measurements. Presents some of their data and a simple analysis for the two-bladed boomerang. (Author/MLH)

  9. Project Narrative

    Energy Technology Data Exchange (ETDEWEB)

    Driscoll, Mary C. [St. Bonaventure University, St Bonaventure, NY(United States)

    2012-07-12

    The Project Narrative describes how the funds from the DOE grant were used to purchase equipment for the biology, chemistry, physics and mathematics departments. The Narrative also describes how the equipment is being used. There is also a list of the positive outcomes as a result of having the equipment that was purchased with the DOE grant.

  10. Radiochemistry Project

    International Nuclear Information System (INIS)

    Anon.

    Researches carried out in the 'Radiochemistry Project' of the Agricultural Nuclear Energy Center, Piracicaba, Sao Paulo State, Brazil, are described. Such researches comprise: dosimetry and radiological protection; development of techniques and methods of chemical analysis and radiochemistry. (M.A.) [pt

  11. FLOAT Project

    DEFF Research Database (Denmark)

    Sørensen, Eigil V.; Aarup, Bendt

    The objective of the FLOAT project is to study the reliability of high-performance fibre-reinforced concrete, also known as Compact Reinforced Composite (CRC), for the floats of wave energy converters. In order to reach a commercial breakthrough, wave energy converters need to achieve a lower price...

  12. Hydrology Project

    International Nuclear Information System (INIS)

    Anon.

    Research carried out in the 'Hydrology Project' of the Centro de Energia Nuclear na Agricultura', Piracicaba, Sao Paulo State, Brazil, are described. Such research comprises: Amazon hydrology and Northeast hydrology. Techniques for the measurement of isotope ratios are used. (M.A.) [pt

  13. CHEMVAL project

    International Nuclear Information System (INIS)

    Chandratillake, M.; Falck, W.E.; Read, D.

    1992-01-01

    This report summarises the development history of the CHEMVAL Thermodynamic Database, the criteria employed for data selection and the contents of Version 4.0, issued to participants on the completion of the project. It accompanies a listing of the database constructed using the dBase III + /IV database management package. (Author)

  14. Project COLD.

    Science.gov (United States)

    Kazanjian, Wendy C.

    1982-01-01

    Describes Project COLD (Climate, Ocean, Land, Discovery) a scientific study of the Polar Regions, a collection of 35 modules used within the framework of existing subjects: oceanography, biology, geology, meterology, geography, social science. Includes a partial list of topics and one activity (geodesic dome) from a module. (Author/SK)

  15. Swedish projects

    International Nuclear Information System (INIS)

    Thunell, J.

    1993-01-01

    The main sources of the financing of Swedish research on gas technology are listed in addition to names of organizations which carry out this research. The titles and descriptions of the projects carried out are presented in addition to lists of reports published with information on prices. (AB)

  16. Project description:

    DEFF Research Database (Denmark)

    Schindel, David E.; Stoeckle, Mark Y.; Milensky, Christopher M.

    2011-01-01

    The Division of Birds, National Museum of Natural History, Smithsonian Institution in Washington, DC, has obtained and released DNA barcodes for 2808 frozen tissue samples. Of the 1,403 species represented by these samples, 1,147 species have not been barcoded previously. This data release increa...

  17. SDN Project

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Rhett [Schweitzer Engineering Laboratories Inc, Pullman, WA (United States)

    2016-12-23

    The SDN Project completed on time and on budget and successfully accomplished 100% of the scope of work outlined in the original Statement of Project Objective (SOPO). The SDN Project formed an alliance between Ameren Corporation, University of Illinois Urbana- Champaign (UIUC), Pacific Northwest National Laboratories (PNNL), and Schweitzer Engineering Laboratories, Inc. (SEL). The objective of the SDN Project is to address Topic Area of Interest 2: Sustain critical energy delivery functions while responding to a cyber-intrusion under Funding Opportunity Announcement DE-FOA-0000797. The goal of the project is to design and commercially release technology that provides a method to sustain critical energy delivery functions during a cyber intrusion and to do this control system operators need the ability to quickly identify and isolate the affected network areas, and re-route critical information and control flows around. The objective of the SDN Project is to develop a Flow Controller that monitors, configures, and maintains the safe, reliable network traffic flows of all the local area networks (LANs) on a control system in the Energy sector. The SDN team identified the core attributes of a control system and produced an SDN flow controller that has the same core attributes enabling networks to be designed, configured and deployed that maximize the whitelisted, deny-bydefault and purpose built networks. This project researched, developed and commercially released technology that: Enables all field networks be to configured and monitored as if they are a single asset to be protected; Enables greatly improved and even precalculated response actions to reliability and cyber events; Supports pre-configured localized response actions tailored to provide resilience against failures and centralized response to cyber-attacks that improve network reliability and availability; Architecturally enables the right subject matter experts, who are usually the information

  18. Project as a System and its Management

    Directory of Open Access Journals (Sweden)

    Jiří Skalický

    2017-06-01

    Full Text Available The contribution aims to describe project as a system, to define project control goal and strategy, control variables and their relationships. Three common control variables represented by the project triangle, are extended by two other important variables – project risk and quality. The control system consists of two components: social one – project manager and project team – and technical one – project dynamic simulation model as a decision making support of project manager in project milestones. In the project planning phase, the project baseline with planned controlled variables is created. In milestones after project launch, the actual values of these variables are measured. If the actual values deviate from planned ones, corrective actions are proposed and new baseline for the following control interval is created. Project plan takes into account the actual project progress and optimum corrective actions are determined by simulation, respecting control strategy and availability of resources. The contribution presents list of references to articles dealing with project as a system and its simulation. In most cases, they refer to the project control using the Earned Value Management method and its derivatives. Using of the dynamic simulation model for project monitoring and control, suggested in this contribution, presents a novel approach. The proposed model can serve as departure point to future research of authors and for development of appropriate and applicable tool.

  19. NPOESS Preparatory Project Validation Program for Atmsophere Data Products from VIIRS

    Science.gov (United States)

    Starr, D.; Wong, E.

    2009-12-01

    The National Polar-orbiting Operational Environmental Satellite Suite (NPOESS) Program, in partnership with National Aeronautical Space Administration (NASA), will launch the NPOESS Preparatory Project (NPP), a risk reduction and data continuity mission, prior to the first operational NPOESS launch. The NPOESS Program, in partnership with Northrop Grumman Aerospace Systems (NGAS), will execute the NPP Validation program to ensure the data products comply with the requirements of the sponsoring agencies. Data from the NPP Visible/Infrared Imager/Radiometer Suite (VIIRS) will be used to produce Environmental Data Records (EDR's) for aerosol and clouds, specifically Aerosol Optical Thickness (AOT), Aerosol Particle Size Parameter (APSP), and Suspended Matter (SM); and Cloud Optical Thickness (COT), Cloud Effective Particle Size (CEPS), Cloud Top Temperature (CTT), Height (CTH) and Pressure (CTP), and Cloud Base Height (CBH). The Aerosol and Cloud EDR Validation Program is a multifaceted effort to characterize and validate these data products. The program involves systematic comparison to heritage data products, e.g., MODIS, and ground-based correlative data, such as AERONET and ARM data products, and potentially airborne field measurements. To the extent possible, the domain is global. The program leverages various investments that have and are continuing to be made by national funding agencies in such resources, as well as the operational user community and the broad Earth science user community. This presentation will provide an overview of the approaches, data and schedule for the validation of the NPP VIIRS Aerosol and Cloud environmental data products.

  20. 20 CFR 266.7 - Accountability of a representative payee.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Accountability of a representative payee. 266.7 Section 266.7 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT REPRESENTATIVE PAYMENT § 266.7 Accountability of a representative payee. (a) A representative...

  1. Projective geometry and projective metrics

    CERN Document Server

    Busemann, Herbert

    2005-01-01

    The basic results and methods of projective and non-Euclidean geometry are indispensable for the geometer, and this book--different in content, methods, and point of view from traditional texts--attempts to emphasize that fact. Results of special theorems are discussed in detail only when they are needed to develop a feeling for the subject or when they illustrate a general method. On the other hand, an unusual amount of space is devoted to the discussion of the fundamental concepts of distance, motion, area, and perpendicularity.Topics include the projective plane, polarities and conic sectio

  2. Projective measure without projective Baire

    DEFF Research Database (Denmark)

    Schrittesser, David; Friedman, Sy David

    We prove that it is consistent (relative to a Mahlo cardinal) that all projective sets of reals are Lebesgue measurable, but there is a ∆13 set without the Baire property. The complexity of the set which provides a counterexample to the Baire property is optimal.......We prove that it is consistent (relative to a Mahlo cardinal) that all projective sets of reals are Lebesgue measurable, but there is a ∆13 set without the Baire property. The complexity of the set which provides a counterexample to the Baire property is optimal....

  3. GOATS Image Projection Component

    Science.gov (United States)

    Haber, Benjamin M.; Green, Joseph J.

    2011-01-01

    When doing mission analysis and design of an imaging system in orbit around the Earth, answering the fundamental question of imaging performance requires an understanding of the image products that will be produced by the imaging system. GOATS software represents a series of MATLAB functions to provide for geometric image projections. Unique features of the software include function modularity, a standard MATLAB interface, easy-to-understand first-principles-based analysis, and the ability to perform geometric image projections of framing type imaging systems. The software modules are created for maximum analysis utility, and can all be used independently for many varied analysis tasks, or used in conjunction with other orbit analysis tools.

  4. Alderney 5 complex demonstration project

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, D. [High Performance Energy Systems, Halifax, NS (Canada)

    2008-07-01

    The Halifax Regional Municipality (HRM) is the largest municipality in Atlantic Canada. This presentation described the flagship facility and the energy efficiency retrofit of five HRM-owned buildings called the Alderney 5 complex. The 5 objectives of the demonstration project involved a district-scale cooling project; replacement of chillers with harbour cooling; and replacement of a high exergy system with a low exergy system. Synergies and challenges of the project were also identified. The presentation also referred to borehole thermal energy storage; existing Halifax Harbour cooling; Halifax Harbour temperatures; cold energy geothermal borehole field; and the benefits of advanced concentric boreholes. A project update and progress to date were also provided. The Alderney 5 project represents the first concentric borehole technology for use to store and retrieve cold energy. tabs., figs.

  5. OECD Halden Reactor Project

    International Nuclear Information System (INIS)

    1988-01-01

    The OECD Halden Reactor project is an agreement between OECD member countries. It was first signed in 1958 and since then regularly renewed every third year. The activities at the Project is centred around the Halden heavy water rector, the HBWR. The reseach programme comprizes studies of fuel performance under various operating conditions, and the application of computers for process control. The HBWR is equipped for exposing fuel rods to temperatures and pressures, and at heat ratings met in modern BWR's and PWR's. A range of in-core instruments are available, permitting detailed measurements of the reactions of the fuel, including mechanical deformations, thermal behaviour, fission gas release, and corrosion. In the area of computer application, the studies of the communication between operator and process, and the surveillance and control of the reactor core, are of particular interst for reactor operation. 1988 represents the 30th year since the Project was started, and this publication is produced to mark this event. It gives and account of the activities and achievements of the Project through the years 1958-1988

  6. Project Radon

    International Nuclear Information System (INIS)

    Ekholm, S.

    1988-01-01

    The project started in March 1987. The objective is to perform radon monitoring in 2000 dwellings occupied by people employed by State Power Board and to continue to contribute to the development of radon filters. The project participates in developing methods for radon measurement and decontamination and in adapting the methods to large scale application. About 400 so called radon trace measurements (coarse measurement) and about 10 action measurements (decontamination measurement) have been made so far. Experience shows that methods are fully applicable and that the decontamination measures recommended give perfectly satisfactory results. It is also established that most of the houses with high radon levels have poor ventilation Many of them suffer from moisture and mould problems. The work planned for 1988 and 1989 will in addition to measurements be directed towards improvement of the measuring methods. An activity catalogue will be prepared in cooperation with ventilation enterprises. (O.S.)

  7. PARTNER Project

    CERN Multimedia

    Ballantine, A; Dixon-Altaber, H; Dosanjh, M; Kuchina, L

    2011-01-01

    Hadrontherapy uses particle beams to treat tumours located near critical organs and tumours that respond poorly to conventional radiation therapy. It has become evident that there is an emerging need for reinforcing research in hadrontherapy and it is essential to train professionals in this rapidly developing field. PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network. The project offers research and training opportunities to 25 young biologists, engineers, physicians and physicists and is allowing them to actively develop modern techniques for treating cancer in close collaboration with leading European Institutions. For this purpose PARTNER relies on cutting edge research and technology development, ef...

  8. Swedish projects

    International Nuclear Information System (INIS)

    Thunell, J.

    1992-01-01

    A description is given of research activities, concerning heating systems, which were carried out in Sweden during 1991. The main subject areas dealt with under the gas technology group within the area of heating systems were catalytic combustion, polyethylene materials, and gas applications within the paper and pulp industries. A list is given of the titles of project reports published during 1991 and of those begun during that year. Under the Swedish Centre for Gas Technology (SGC), the main areas of research regarding gas applications were polyethylene materials, industrial applications and the reduction of pollutant emissions. A detailed list is given of research projects which were in progress or proposed by March 1992 under the heating system gas technology research group in Sweden. This list also presents the aims and descriptions of the methods, etc. (AB)

  9. AVE project

    International Nuclear Information System (INIS)

    2004-01-01

    During 1998, ANAV began to optimize Human Resources to cope with the ERE and ANA-ANV integration. Project AVE was intended to achieve an orderly transfer of know-how, skills, attitudes and experiences. The most complex part was renovation of personnel with Operating Licenses. Nearly 140 people had joined the organization by late December 2003. This opportunity was seized to draw up a new Training Manual, and a common Initial Training Plan was designed for the two plants, accounting for the singularities of each one. The plan is divided into 5 modules: Common Training, Specific Training, PEI/CAT, Management, and on-the-job Training. The training environments were defined according to the nature of the capabilities to be acquired. Project AVE resulted in the merger of the Asco and Vandellos II Training services. (Author)

  10. Spent Nuclear Fuel project, project management plan

    International Nuclear Information System (INIS)

    Fuquay, B.J.

    1995-01-01

    The Hanford Spent Nuclear Fuel Project has been established to safely store spent nuclear fuel at the Hanford Site. This Project Management Plan sets forth the management basis for the Spent Nuclear Fuel Project. The plan applies to all fabrication and construction projects, operation of the Spent Nuclear Fuel Project facilities, and necessary engineering and management functions within the scope of the project

  11. ARTIST Project

    CSIR Research Space (South Africa)

    Ferguson, K

    2012-10-01

    Full Text Available Biennial Conference Presented by: Keith Ferguson Date: 9 October 2012 Mobile IPTV Broadcasting Platform Consortium: CSIR, UCT, ECA Funded by TIA 2008-2011 ARTIST Project Min time - sacrifice quality Max quality - sacrifice time Application Context... idth > ARTIST Platform Advertiser Client 1 Client 2 Client 3 Client 4 Sport channel News channel Wildlife channel Advert database Transaction database Transcoder Servers Media Switching Servers INTERNET Channel viewing Advert upload...

  12. CARA project

    International Nuclear Information System (INIS)

    Bergallo, Juan E.; Brasnarof, Daniel O.

    2000-01-01

    The CARA (Advanced Fuels for Argentine Reactors) Project successfully completed its first stage, phase one, last year. The performance of this fuel has been partially examined, using CNEA and CONUAR facilities and personnel. With the results obtained in this stage, determined by the corresponding tests and verification of the fuel behavior, the performance of the second stage started immediately afterwards. Works performed and results obtained during the development of the second stage are generally described in this paper. (author)

  13. Polytope projects

    CERN Document Server

    Iordache, Octavian

    2013-01-01

    How do you know what works and what doesn't? This book contains case studies highlighting the power of polytope projects for complex problem solving. Any sort of combinational problem characterized by a large variety of possibly complex constructions and deconstructions based on simple building blocks can be studied in a similar way. Although the majority of case studies are related to chemistry, the method is general and equally applicable to other fields for engineering or science.

  14. Projection Methods

    DEFF Research Database (Denmark)

    Wagner, Falko Jens; Poulsen, Mikael Zebbelin

    1999-01-01

    When trying to solve a DAE problem of high index with more traditional methods, it often causes instability in some of the variables, and finally leads to breakdown of convergence and integration of the solution. This is nicely shown in [ESF98, p. 152 ff.].This chapter will introduce projection...... methods as a way of handling these special problems. It is assumed that we have methods for solving normal ODE systems and index-1 systems....

  15. Project Phaseolus

    International Nuclear Information System (INIS)

    Anon.

    Research carried out through the Phaseolus Project of the 'Centro de Energia Nuclear na Agricultura' (CENA) Piracicaba, Sao Paulo State, Brazil, is described. It comprises the following subject s: plant breeding; nitrogen fixation; tissue cultures; proteins; photosynthetic efficiency; soil-plant interactions; electron microscopy of the golden mosaic virus; pest control; production of 15 N-enriched ammonium sulfate, and determination of elements in the beans plant. (M.A.) [pt

  16. Numatron project

    Energy Technology Data Exchange (ETDEWEB)

    Sugimoto, K [Osaka Univ., Toyonaka (Japan). Dept. of Physics; Hirao, Yasuo

    1977-04-01

    A project of high energy heavy ion acceleration is under consideration. The high energy heavy ions can produce highly condensed states of nuclei. A new phase of nucleus would be seen at the incident energy higher than 140 MeV/nucleon. High energy heavy ions causing high density states and meson emission will produce various new nuclides. Process of formation of atomic elements will be studied. Various fields of science can be also investigated by the high energy heavy ions. Spectroscopic study of multi-valent ions will be made high energy uranium. Study of materials for the fusion reactor is important. Impurity heavy ion from the wall of the fusion reactor may lose the energy of the reactor, and the characteristic features of heavy ions should be investigated. The highly ionized states of atoms are also produced by heavy ion injection into material. Several projects of heavy ion acceleration are in progress in the world. The Numatron project in Japan is to construct a combination machine of a Cockcroft type machine, three linear accelerator and a synchrotron. The planned energy of the machine is 670 MeV/nucleon. Technical problems are under investigation.

  17. Project Design Concept for Monitoring and Control System

    International Nuclear Information System (INIS)

    MCGREW, D.L.

    2000-01-01

    This Project Design Concept represents operational requirements established for use in design the tank farm Monitoring and Control System. These upgrades are included within the scope of Project W-314, Tank Farm Restoration and Safe Operations

  18. Project Guardian: Optimizing Electronic Warfare Systems for Ground Combat Vehicles

    National Research Council Canada - National Science Library

    Parks, Jack G; Jackson, William; Revello, James; Soltesz, James

    1995-01-01

    .... The study, Project Guardian, represents a new process for determining the optimum set of sensors and countermeasures for a specific vehicle class under the constraints of threat projection, combat...

  19. Fisheries Restoration Grant Program Projects [ds168

    Data.gov (United States)

    California Natural Resource Agency — This shapefile (FRGP_All_020209.shp) represents the locations of all ongoing and completed salmonid restoration projects in California with existing records in the...

  20. Marketing norm perception among medical representatives in Indian pharmaceutical industry.

    Science.gov (United States)

    Nagashekhara, Molugulu; Agil, Syed Omar Syed; Ramasamy, Ravindran

    2012-03-01

    Study of marketing norm perception among medical representatives is an under-portrayed component that deserves further perusal in the pharmaceutical industry. The purpose of this study is to find out the perception of marketing norms among medical representatives. The research design is quantitative and cross sectional study with medical representatives as unit of analysis. Data is collected from medical representatives (n=300) using a simple random and cluster sampling using a structured questionnaire. Results indicate that there is no difference in the perception of marketing norms among male and female medical representatives. But there is a difference in opinion among domestic and multinational company's medical representatives. Educational back ground of medical representatives also shows the difference in opinion among medical representatives. Degree holders and multinational company medical representatives have high perception of marketing norms compare to their counterparts. The researchers strongly believe that mandatory training on marketing norms is beneficial in decision making process during the dilemmas in the sales field.

  1. Coloss project

    International Nuclear Information System (INIS)

    2005-01-01

    The COLOSS project was a shared-cost action, co-ordinated by IRSN within the Euratom Research Framework Programme 1998-2002. Started in February 2000, the project lasted three years. The work-programme performed by 19 partners was shaped around complementary activities aimed at improving severe accident codes. Unresolved risk-relevant issues regarding H2 production, melt generation and the source term were studied, through a large number of experiments such as a) dissolution of fresh and high burn-up UO 2 and MOX by molten Zircaloy, b) simultaneous dissolution of UO 2 and ZrO 2 by molten Zircaloy, c) oxidation of U-O-Zr mixtures by steam, d) degradation-oxidation of B 4 C control rods. Significant results have been produced from separate-effects, semi-global and large-scale tests on COLOSS topics. Break-through were achieved on some issues. Nevertheless, more data are needed for consolidation of the modelling on burn-up effects on UO 2 and MOX dissolution and on oxidation of U-O-Zr and B 4 C-metal mixtures. There was experimental evidence that the oxidation of these mixtures can contribute significantly to the large H2 production observed during the reflooding of degraded cores under severe accident conditions. Based on the experimental results obtained on the COLOSS topics, corresponding models were developed and were successfully implemented in several severe accident codes. Upgraded codes were then used for plant calculations to evaluate the consequences of new models on key severe accident sequences occurring in different plants designs involving B 4 C control rods (EPR, BWR, VVER- 1000) as well as in the TMI-2 accident. The large series of plant calculations involved sensitivity studies and code benchmarks. Main severe accident codes in use in the EU for safety studies were used such as ICARE/CATHARE, SCDAP/RELAP5, ASTEC, MELCOR and MAAP4. This activity enabled: a) the assessment of codes to calculate core degradation, b) the identification of main

  2. Hanford Environmental Dose Reconstruction Project

    International Nuclear Information System (INIS)

    McMakin, A.H.; Cannon, S.D.; Finch, S.M.

    1992-07-01

    The objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The TSP consists of experts in environmental pathways, epidemiology, surface-water transport, ground-water transport, statistics, demography, agriculture, meteorology, nuclear engineering, radiation dosimetry, and cultural anthropology. Included are appointed technical members representing the states of Oregon, Washington, and Idaho, a representative of Native American tribes, and an individual representing the public. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed from release to impact on humans (dose estimates): Source terms, environmental transport, environmental monitoring data, demography, food consumption, and agriculture, and environmental pathways and dose estimates. Progress is discussed

  3. Project Exodus

    Science.gov (United States)

    1990-01-01

    Project Exodus is an in-depth study to identify and address the basic problems of a manned mission to Mars. The most important problems concern propulsion, life support, structure, trajectory, and finance. Exodus will employ a passenger ship, cargo ship, and landing craft for the journey to Mars. These three major components of the mission design are discussed separately. Within each component the design characteristics of structures, trajectory, and propulsion are addressed. The design characteristics of life support are mentioned only in those sections requiring it.

  4. CAREM Project

    International Nuclear Information System (INIS)

    Ishida, Viviana; Gomez, Silvia

    2001-01-01

    CAREM project consists on the development and design of an advanced nuclear power plant. CAREM is a very low power innovative reactor conceived with new generation design solutions. Based on an indirect cycle integrated light water reactor using enriched uranium, CAREM has some distinctive features that greatly simplify the reactor and also contribute to a high level of safety: integrated primary system, primary system cooling by natural convection, self pressurization, and passive safety systems. In order to verify its innovative features the construction of a prototype is planned. (author)

  5. Free-flow speeds for representative road and terrain types

    CSIR Research Space (South Africa)

    Schutte, IC

    2009-06-02

    Full Text Available Speed plays an important role in the justification of road infrstructure projects. It affects both vehicle operating cost and travel time cost. If incorrecr values for speed are used in the economic analyses of transport projects, incorrect...

  6. Statistics On Title II Direct Payments To Claimant Representatives

    Data.gov (United States)

    Social Security Administration — Every person has the right to be represented by an attorney or other representative while pursuing a claim or other rights. This dataset contains data around Title...

  7. 20 CFR 416.1520 - Fee for a representative's services.

    Science.gov (United States)

    2010-04-01

    ... AGED, BLIND, AND DISABLED Representation of Parties § 416.1520 Fee for a representative's services. (a... you or your representative from contacting us in person or in writing. (B) There was a death or...

  8. 20 CFR 404.1720 - Fee for a representative's services.

    Science.gov (United States)

    2010-04-01

    ... DISABILITY INSURANCE (1950- ) Representation of Parties § 404.1720 Fee for a representative's services. (a... you or your representative from contacting us in person or in writing. (B) There was a death or...

  9. Integrated Project Teams - An Essential Element of Project Management during Project Planning and Execution - 12155

    Energy Technology Data Exchange (ETDEWEB)

    Burritt, James G.; Berkey, Edgar [Longenecker and Associates, Las Vegas, NV 89135 (United States)

    2012-07-01

    Managing complex projects requires a capable, effective project manager to be in place, who is assisted by a team of competent assistants in various relevant disciplines. This team of assistants is known as the Integrated Project Team (IPT). he IPT is composed of a multidisciplinary group of people who are collectively responsible for delivering a defined project outcome and who plan, execute, and implement over the entire life-cycle of a project, which can be a facility being constructed or a system being acquired. An ideal IPT includes empowered representatives from all functional areas involved with a project-such as engineering design, technology, manufacturing, test and evaluation, contracts, legal, logistics, and especially, the customer. Effective IPTs are an essential element of scope, cost, and schedule control for any complex, large construction project, whether funded by DOE or another organization. By recently assessing a number of major, on-going DOE waste management projects, the characteristics of high performing IPTs have been defined as well as the reasons for potential IPT failure. Project managers should use IPTs to plan and execute projects, but the IPTs must be properly constituted and the members capable and empowered. For them to be effective, the project manager must select the right team, and provide them with the training and guidance for them to be effective. IPT members must treat their IPT assignment as a primary duty, not some ancillary function. All team members must have an understanding of the factors associated with successful IPTs, and the reasons that some IPTs fail. Integrated Project Teams should be used by both government and industry. (authors)

  10. PORTNUS Project

    Energy Technology Data Exchange (ETDEWEB)

    Loyal, Rebecca E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-07-14

    The objective of the Portunus Project is to create large, automated offshore ports that will the pace and scale of international trade. Additionally, these ports would increase the number of U.S. domestic trade vessels needed, as the imported goods would need to be transported from these offshore platforms to land-based ports such as Boston, Los Angeles, and Newark. Currently, domestic trade in the United States can only be conducted by vessels that abide by the Merchant Marine Act of 1920 – also referred to as the Jones Act. The Jones Act stipulates that vessels involved in domestic trade must be U.S. owned, U.S. built, and manned by a crew made up of U.S. citizens. The Portunus Project would increase the number of Jones Act vessels needed, which raises an interesting economic concern. Are Jones Act ships more expensive to operate than foreign vessels? Would it be more economically efficient to modify the Jones Act and allow vessels manned by foreign crews to engage in U.S. domestic trade? While opposition to altering the Jones Act is strong, it is important to consider the possibility that ship-owners who employ foreign crews will lobby for the chance to enter a growing domestic trade market. Their success would mean potential job loss for thousands of Americans currently employed in maritime trade.

  11. The Stripa project. Annual report 1990

    International Nuclear Information System (INIS)

    1991-07-01

    The Stripa project is an international project being performed under the sponsorship of the OECD Nuclear Energy Agency (NEA). The project concerns research related to the disposal of highly radioactive waste in crystalline rock. The research and development division of the Swedish Nuclear Fuel and Waste Management Co. (SKB) has been entrusted with the management of the project, under the direction of representatives from each participating country. The aim of this report is to inform the OECD Nuclear Energy Agency and the participants in the project about the general progress of work during 1990

  12. The Stripa project. Annual report 1988

    International Nuclear Information System (INIS)

    1989-05-01

    The Stripa project is an international project being performed under the sponsorship of the OECD Nuclear Energy Agency (NEA). The project concerns research related to the disposal of highly radioactive waste in crystalline rock. The Research and Development Division of the Swedish Nuclear Fuel and Waste Management Company (SKB) hsa been enstrusted with the management of the project, under the direction of representatives from each participating country. The aim of this report is to inform the OECD Nuclear Energy Agency and the participants in the project about the general progress of work during 1988. (36 figs., 4 tabs.)

  13. The Stripa project annual report 1991

    International Nuclear Information System (INIS)

    1992-05-01

    The Stripa project is an international project being performed under the sponsorship of the OECD Nuclear Energy Agency (NEA). The project concerns research related to the disposal of highly radioactive waste in crystalline rock. The Research and Development Division of the Swedish Nuclear Fuel and Waste Management Company (SKB) has been entrusted with the management of the project, under the direction of representatives from each participating country. The aim of this report is to inform the OECD Nuclear Energy Agency and the participants in the project about the general progress of work during 1991

  14. SISCAL project

    Science.gov (United States)

    Santer, Richard P.; Fell, Frank

    2003-05-01

    The first "ocean colour" sensor, Coastal Zone Color Scanner (CZCS), was launched in 1978. Oceanographers learnt a lot from CZCS but it remained a purely scientific sensor. In recent years, a new generation of satellite-borne earth observation (EO) instruments has been brought into space. These instruments combine high spectral and spatial resolution with revisiting rates of the order of one per day. More instruments with further increased spatial, spectral and temporal resolution will be available within the next years. In the meantime, evaluation procedures taking advantage of the capabilities of the new instruments were derived, allowing the retrieval of ecologically important parameters with higher accuracy than before. Space agencies are now able to collect and to process satellite data in real time and to disseminate them via the Internet. It is therefore meanwhile possible to envisage using EO operationally. In principle, a significant demand for EO data products on terrestrial or marine ecosystems exists both with public authorities (environmental protection, emergency management, natural resources management, national parks, regional planning, etc) and private companies (tourist industry, insurance companies, water suppliers, etc). However, for a number of reasons, many data products that can be derived from the new instruments and methods have not yet left the scientific community towards public or private end users. It is the intention of the proposed SISCAL (Satellite-based Information System on Coastal Areas and Lakes) project to contribute to the closure of the existing gap between space agencies and research institutions on one side and end users on the other side. To do so, we intend to create a data processor that automatically derives and subsequently delivers over the Internet, in Near-Real-Time (NRT), a number of data products tailored to individual end user needs. The data products will be generated using a Geographical Information System (GIS

  15. 40 CFR 72.22 - Alternate designated representative.

    Science.gov (United States)

    2010-07-01

    ... designated representative is selected shall include a procedure for the owners and operators of the source and affected units at the source to authorize the alternate designated representative to act in lieu...) In the event of a conflict, any action taken by the designated representative shall take precedence...

  16. 22 CFR 23.4 - Representative value in exchange.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Representative value in exchange. 23.4 Section 23.4 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS FINANCE AND ACCOUNTING § 23.4 Representative value in exchange. Representative value in exchange for the collection of a fee means foreign...

  17. 40 CFR 60.4111 - Alternate Hg designated representative.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Alternate Hg designated representative... Times for Coal-Fired Electric Steam Generating Units Hg Designated Representative for Hg Budget Sources § 60.4111 Alternate Hg designated representative. (a) A certificate of representation under § 60.4113...

  18. USEPAM Project: The State of Progress

    DEFF Research Database (Denmark)

    Lund, Søren

    The paper represents the introductory speech at the 2nd regional workshop of the USEPAM project in Phnom Penh March 2005. It gives a review of the project's activities and achievements, and an introduction to the objectives, structure and programme of the workshop...

  19. CENELEC Project Report Smart House Roadmap (draft)

    NARCIS (Netherlands)

    Hartog, F.T.H. den; Suters, T.; Parsons, J.; Faller, J.

    2010-01-01

    This CENELEC project report has been drafted by a project team and steering group of representatives of interested parties and is to be endorsed on 2010-11-23. Neither the national members of CENELEC nor the CEN-CENELEC Management Centre can be held accountable for the technical content of this

  20. Project Financing

    OpenAIRE

    S. GATTI

    2005-01-01

    Στην εισαγωγή της παρούσας εργασίας δίνεται ο ορισμός του project financing, τα ιστορικά στοιχεία και οι τάσεις αγοράς του. Στο πρώτο κεφάλαιο αναφέρεται γιατί οι εταιρείες προτιμούν την χρηματοδότηση με project financing. Γίνεται λόγος για τα πλεονεκτήματά του έναντι της άμεσης χρηματοδότησης, καθώς και για τα μειονεκτήματα του project financing. Στο δεύτερο κεφάλαιο παρουσιάζονται τα χρηματοοικονομικά στοιχεία και ο ρόλος του χρηματοοικονομικού συμβούλου. Στην τρίτη ενότητα γίνεται η αναγνώ...

  1. Scheduling of resource-constrained projects

    CERN Document Server

    Klein, Robert

    2000-01-01

    Project management has become a widespread instrument enabling organizations to efficiently master the challenges of steadily shortening product life cycles, global markets and decreasing profit margins. With projects increasing in size and complexity, their planning and control represents one of the most crucial management tasks. This is especially true for scheduling, which is concerned with establishing execution dates for the sub-activities to be performed in order to complete the project. The ability to manage projects where resources must be allocated between concurrent projects or even sub-activities of a single project requires the use of commercial project management software packages. However, the results yielded by the solution procedures included are often rather unsatisfactory. Scheduling of Resource-Constrained Projects develops more efficient procedures, which can easily be integrated into software packages by incorporated programming languages, and thus should be of great interest for practiti...

  2. PUREX transition project case study

    International Nuclear Information System (INIS)

    Jasen, W.G.

    1996-01-01

    In December 1992, the US Department of Energy (DOE) directed that the Plutonium-Uranium Extraction (PUREX) Plant be shut down and deactivated because it was no longer needed to support the nation's production of weapons-grade plutonium. The PUREX/UO 2 Deactivation Project will establish a safe and environmentally secure configuration for the facility and preserve that configuration for 10 years. The 10-year span is used to predict future maintenance requirements and represents the estimated time needed to define, authorize, and initiate the follow-on decontamination and decommissioning activities. Accomplishing the deactivation project involves many activities. Removing major hazards, such as excess chemicals, spent fuel, and residual plutonium are major goals of the project. The scope of the PUREX Transition Project is described within

  3. Big gas project for Australia

    International Nuclear Information System (INIS)

    Jemain, A.

    2005-01-01

    Australia is re-launching its ambitions in liquefied natural gas (LNG) with the Greater Gorgon project of offshore exploitation of the natural gas reserves of the continental shelf of NW Australia. These reserves would represent 200 million tons of LNG which will be exported towards China and USA. The project will cost 11 billion dollars and will yield 2 billion dollars per year. It is managed by a consortium which groups together Chevron Corp. (50%), Shell (25%) and ExxonMobil (25%). Technip company is partner of the project. The China National Offshore Oil Corp (CNOOC) has announced its intention to become also partner of the project, and maybe Japan, South Korea and Taiwan will wish too. Short paper. (J.S.)

  4. The Design of Project Management Structural Organization

    OpenAIRE

    Dumitru Constantinescu; Cristian Etegan

    2007-01-01

    The relationships organization-suppliers-customers have recently known major changes in the structure of services and have made the organization develop its managerial and professional competencies in order to do projects. The qualified organization is the most trust-worthy in the process of doing a project. The participation of an organization in doing projects depends on a multitude of factors. Out of these factors, the structural organization comes forth, as it represents the variable with...

  5. Key performance indicators for successful simulation projects

    OpenAIRE

    Jahangirian, M; Taylor, SJE; Young, T; Robinson, S

    2016-01-01

    There are many factors that may contribute to the successful delivery of a simulation project. To provide a structured approach to assessing the impact various factors have on project success, we propose a top-down framework whereby 15 Key Performance Indicators (KPI) are developed that represent the level of successfulness of simulation projects from various perspectives. They are linked to a set of Critical Success Factors (CSF) as reported in the simulation literature. A single measure cal...

  6. Project: Ultracentrifuges

    International Nuclear Information System (INIS)

    Olea C, O.

    1990-07-01

    The trans elastic ultracentrifuge of magnetic suspension, is an instrument that arose of an interdisciplinary group directed by the Dr. James Clark Keith where it was projected, designed and built a centrifuge that didn't exist, to be applied in forced diffusion of uranium, like one of the many application fields. The written present, has as purpose to give to know the fundamental physical principles of this technology, its fundamental characteristics of design, the application of this in the separation process of isotopes, as well as the previous studies and essential control parameters in the experimental processes, the same thing that, the most outstanding results and the detection systems used in the confirmation and finally, the carried out potential applications of the principles of the ultracentrifugation technology. (Author)

  7. ENVISION Project

    CERN Multimedia

    Ballantine, A; Dixon-Altaber, H; Dosanjh, M; Kuchina, L

    2011-01-01

    Hadrontherapy is a highly advanced technique of cancer radiotherapy that uses beams of charged particles (ions) to destroy tumour cells. While conventional X-rays traverse the human body depositing radiation as they pass through, ions deliver most of their energy at one point. Hadrontherapy is most advantageous once the position of the tumour is accurately known, so that healthy tissues can be protected. Accurate positioning is a crucial challenge for targeting moving organs, as in lung cancer, and for adapting the irradiation as the tumour shrinks with treatment. Therefore, quality assurance becomes one of the most relevant issues for an effective outcome of the cancer treatment. In order to improve the quality assurance tools for hadrontherapy, the European Commission is funding ENVISION, a 4-year project that aims at developing solutions for: real-• time non invasive monitoring • quantitative imaging • precise determination of delivered dose • fast feedback for optimal treatment planning • real-t...

  8. High School Students' Perception of University Students as STEM Representatives

    DEFF Research Database (Denmark)

    Poulsen, Eva Lykkegaard

    ’ potential identities. It shows that the students preferred STEM representatives resembled themselves in some aspects (primarily social and health aspects) and fit their perceptions of a typical person working in STEM in other aspects (knowledge seeking, hard-working etc.). At least two different...... studies, it is important to introduce high school students to good STEM representatives to make possible the development of potential STEM identities. A potential identity within a specific subject area relies on at least a situation bound relation-ship to the subject area or the person representing it....... Some representatives transmit infor-mation and are thereby definers, whereas other representatives illustrates as personal examples and are thereby models. This study focuses on high school students’ views on STEM representatives and the impact these representatives have on the high school students...

  9. EUROTRAC projects

    International Nuclear Information System (INIS)

    Slanina, J.; Arends, B.G.; Wyers, G.P.

    1992-07-01

    The projects discussed are BIATEX (BIosphere-ATmosphere EXchange of pollutants), ACE (Acidity in Clouds Experiment) and GCE (Ground-based Cloud Experiment). ECN also coordinates BIATEX and contributes to the coordination of EUROTRAC. Research in BIATEX is aimed at the development of equipment, by which atmosphere-surface interactions of air pollution can be quantified. A ion chromatograph, connected to a rotating denuder, is developed to be applicated in the field for on-line analysis of denuder extracts and other samples. To investigate dry deposition of ammonia a continuous-flow denuder has been developed. A thermodenuder system to measure the concentrations of HNO 3 and NH 4 NO 3 in the ambient air is optimized to determine depositions and is part of the ECN monitoring station in Zegveld, Netherlands. An aerosol separation technique, based on a cyclone separator, has also been developed. All this equipment has been used in field experiments above wheat and heather. An automated monitoring station for long-term investigations of NH 3 , HNO 3 and SO 2 dry deposition on grassland and the impact of the deposition on the presence and composition of water films has been set up and fully tested. Research in GCE concerns the uptake and conversion of air pollution in clouds (cloud chemistry). Measuring equipment from several collaborative institutes has been specified and calibrated in a cloud chamber at ECN. The ECN contribution is the determination of the gas phase composition and the micro-physical characterization of the clouds. Measurement campaigns were carried out in the Po area (Italy) in fog, and in Kleiner Feldberg near Frankfurt, Germany, in orographic clouds. Estimations are given of the deposition of fog water and cloud water on forests in the Netherlands and the low mountain range in Germany. The project ACE was not started because of financial reasons and will be reconsidered. 26 figs., 1 tab., 3 apps., 34 refs

  10. Project Hanford management contract quality improvement project management plan; TOPICAL

    International Nuclear Information System (INIS)

    ADAMS, D.E.

    1999-01-01

    On July 13, 1998, the U.S. Department of Energy, Richland Operations Office (DOE-RL) Manager transmitted a letter to Fluor Daniel Hanford, Inc. (FDH) describing several DOE-RL identified failed opportunities for FDH to improve the Quality Assurance (QA) Program and its implementation. In addition, DOE-RL identified specific Quality Program performance deficiencies. FDH was requested to establish a periodic reporting mechanism for the corrective action program. In a July 17, 1998 response to DOE-RL, FDH agreed with the DOE concerns and committed to perform a comprehensive review of the Project Hanford Management Contract (PHMC) QA Program during July and August, 1998. As a result, the Project Hanford Management Contract Quality Improvement Plan (QIP) (FDH-3508) was issued on October 21, 1998. The plan identified corrective actions based upon the results of an in-depth Quality Program Assessment. Immediately following the scheduled October 22, 1998, DOE Office of Enforcement and Investigation (EH-10) Enforcement Conference, FDH initiated efforts to effectively implement the QIP corrective actions. A Quality Improvement Project (QI Project) leadership team was assembled to prepare a Project Management Plan for this project. The management plan was specifically designed to engage a core team and the support of representatives from FDH and the major subcontractors (MSCs) to implement the QIP initiatives; identify, correct, and provide feedback as to the root cause for deficiency; and close out the corrective actions. The QI Project will manage and communicate progress of the process

  11. Tenth working group meeting of representatives of RCA Member States. Report

    International Nuclear Information System (INIS)

    1989-04-01

    The Tenth RCA (Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology) Working Group meeting of representatives of RCA Member States was held at the Chinese Academy of Agricultural Sciences, Beijing, between 11-14 April 1988. The report on the meeting consists of a presentation of the seven technical sessions which dealt with topics such as nuclear techniques in industry, agriculture and medicine, nuclear power and of the project reports under RCA

  12. Project Success in IT Project Management

    OpenAIRE

    Siddiqui, Farhan Ahmed

    2010-01-01

    The rate of failed and challenged Information Technology (IT) projects is too high according to the CHAOS Studies by the Standish Group and the literature on project management (Standish Group, 2008). The CHAOS Studies define project success as meeting the triple constraints of scope, time, and cost. The criteria for project success need to be agreed by all parties before the start of the project and constantly reviewed as the project progresses. Assessing critical success factors is another ...

  13. Project LASER

    Science.gov (United States)

    1990-01-01

    NASA formally launched Project LASER (Learning About Science, Engineering and Research) in March 1990, a program designed to help teachers improve science and mathematics education and to provide 'hands on' experiences. It featured the first LASER Mobile Teacher Resource Center (MTRC), is designed to reach educators all over the nation. NASA hopes to operate several MTRCs with funds provided by private industry. The mobile unit is a 22-ton tractor-trailer stocked with NASA educational publications and outfitted with six work stations. Each work station, which can accommodate two teachers at a time, has a computer providing access to NASA Spacelink. Each also has video recorders and photocopy/photographic equipment for the teacher's use. MTRC is only one of the five major elements within LASER. The others are: a Space Technology Course, to promote integration of space science studies with traditional courses; the Volunteer Databank, in which NASA employees are encouraged to volunteer as tutors, instructors, etc; Mobile Discovery Laboratories that will carry simple laboratory equipment and computers to provide hands-on activities for students and demonstrations of classroom activities for teachers; and the Public Library Science Program which will present library based science and math programs.

  14. Project Longshot

    Science.gov (United States)

    West, J. Curtis; Chamberlain, Sally A.; Stevens, Robert; Pagan, Neftali

    1989-01-01

    Project Longshot is an unmanned probe to our nearest star system, Alpha Centauri, 4.3 light years away. The Centauri system is a trinary system consisting of two central stars (A and B) orbiting a barycenter, and a third (Proxima Centauri) orbiting the two. The system is a declination of -67 degrees. The goal is to reach the Centauri system in 50 years. This time space was chosen because any shorter time would be impossible of the relativistic velocities involved, and any greater time would be impossible because of the difficulty of creating a spacecraft with such a long lifetime. Therefore, the following mission profile is proposed: (1) spacecraft is assembled in Earth orbit; (2) spacecraft escapes Earth and Sun in the ecliptic with a single impulse maneuver; (3) spacecraft changed declination to point toward Centauri system; (4) spacecraft accelerates to 0.1c; (5) spacecraft coasts at 0.1c for 41 years; (6) spacecraft decelerates upon reaching Centauri system; and (7) spacecraft orbits Centauri system, conducts investigations, and relays data to Earth. The total time to reach the Centauri system, taking into consideration acceleration and deceleration, will be approximately 50 years.

  15. High School Students' Perception of University Students as STEM Representatives

    DEFF Research Database (Denmark)

    Poulsen, Eva Lykkegaard

    The Danish government has an ambition to recruit more high school students into STEM edu-cations (science, technology, engineering and/or mathematics). The students’ choice of further education is based on the people and jobs they have knowledge of. Therefore, to recruit more students into STEM....... Some representatives transmit infor-mation and are thereby definers, whereas other representatives illustrates as personal examples and are thereby models. This study focuses on high school students’ views on STEM representatives and the impact these representatives have on the high school students...... studies, it is important to introduce high school students to good STEM representatives to make possible the development of potential STEM identities. A potential identity within a specific subject area relies on at least a situation bound relation-ship to the subject area or the person representing it...

  16. Assessing Use of Cognitive Heuristic Representativeness in Clinical Reasoning

    OpenAIRE

    Payne, Velma L.; Crowley, Rebecca S.

    2008-01-01

    We performed a pilot study to investigate use of the cognitive heuristic Representativeness in clinical reasoning. We tested a set of tasks and assessments to determine whether subjects used the heuristics in reasoning, to obtain initial frequencies of heuristic use and related cognitive errors, and to collect cognitive process data using think-aloud techniques. The study investigates two aspects of the Representativeness heuristic - judging by perceived frequency and representativeness as ca...

  17. SPECIFICITY OF THE PROJECTIVE FIELD: REVERIES AND TRANSFORMATIVE POTENTIALITIES

    OpenAIRE

    Tiziana Sola

    2014-01-01

    This article suggests a reading of the projectives Methods in Bionian key, with particular reference to the bionian elaboration by Antonino Ferro, who substantially considers the patient’s associative flows as forms of the oneiric. The projective situation also represents a place of induction to reverie, in resonance with the concept of projective field, the peculiarity of which lie in the introduction of the element “third”, i.e. the test material.Keywords: Projective methods - Projective fi...

  18. A Multi-Agent Framework Manages a Representative Sensor Web

    Science.gov (United States)

    Suri, D.; Schmidt, D.; Biswas, G.; Kinnebrew, J.; Otte, W.; Shankaran, N.

    2008-12-01

    NASA's vision of a Sensor Web (which includes a distributed global observation system) consists of a large number of elements, such as remote spacecraft hosting multiple instruments, in situ terrestrial and oceanic sensor networks, and airborne assets. Researchers and developers of a Sensor web face a number of challenges that arise from (1) the inherent heterogeneous and geographical distributed nature of the Sensor web; (2) the myriad mission goals and objectives that must be satisfied by the Sensor web, ranging from an improved understanding of earth science, weather forecasting, and disaster management to an alleviation of societal problems; and (3) the need to support myriad operational modes, such as long and short-term monitoring and targeted observations. Resolving these challenges requires some form of autonomy - typically embodied in software. Agent technology has emerged both as a salient purveyor of entities that exhibit autonomous behavior and also as a paradigm for constructing complex software systems with a large number of interacting heterogeneous components. This paper describes our experiences integrating the Multi-agent Architecture for Coordinated Responsive Observations (MACRO) into the SouthEast Alaska MOnitoring Network for Science, Telecommunications, Education, and Research (SEAMONSTER). MACRO provides agents at (1) the mission level, where agents interact with users to define science goals and then translate these goals into a set of prioritized tasks that have to be executed to achieve these goals, and (2) the resource level, where agents translate tasks into activities related to data collection, data analysis, and data communication. As a representative small-scale sensor web situated in multiple locations on the Juneau Icefield, SEAMONSTER affords an unparalleled opportunity to develop, mature, and showcase MACRO's multi-level agent capabilities. MACRO is developed by the Lockheed Martin Space System Company's Advanced Technology

  19. Determination of representative CANDU feeder dimensions for engineering simulator

    International Nuclear Information System (INIS)

    Cho, S.; Muzumdar, A.

    1996-01-01

    This paper describes a logic for selection of representative channel groups and a methodology for determination of representative CANDU feeder dimensions and the pressure drops between inlet/outlet header and fuel channel in the primary loop. A code, MEDOC, was developed based on this logic and methodology and helps perform a calculation of representative feeder dimensions for a selected channel group on the basis of feeder geometry data (fluid volume, mass flow rate, loss factor) and given property data (pressure, quality, density) at inlet/outlet header. The representative feeder dimensions calculated based on this methodology will be useful for the engineering simulator for the CANDU type reactor. (author)

  20. DFS Associates: Simple ways to become a good manufacturer's representative

    OpenAIRE

    Sandra K. Pharre

    2018-01-01

    Being one of the trusted manufacturer’s representative firms for RF and microwave products and services, DFS Associates wanted to impart a few insights to consider in becoming a good manufacturer’s representative with this article. Firstly, you need to understand what it does if you’re interested on becoming one where it could be an individual or a small business that can represent a manufacturer’s products and services effectively to the marketplace. You can choose between representing one m...

  1. Project Success in Agile Development Software Projects

    Science.gov (United States)

    Farlik, John T.

    2016-01-01

    Project success has multiple definitions in the scholarly literature. Research has shown that some scholars and practitioners define project success as the completion of a project within schedule and within budget. Others consider a successful project as one in which the customer is satisfied with the product. This quantitative study was conducted…

  2. Ace Project as a Project Management Tool

    Science.gov (United States)

    Cline, Melinda; Guynes, Carl S.; Simard, Karine

    2010-01-01

    The primary challenge of project management is to achieve the project goals and objectives while adhering to project constraints--usually scope, quality, time and budget. The secondary challenge is to optimize the allocation and integration of resources necessary to meet pre-defined objectives. Project management software provides an active…

  3. Organizations, projects and culture

    NARCIS (Netherlands)

    J. van Cleeff; Pieter van Nispen tot Pannerden

    2016-01-01

    Purpose: to explore and demonstrate the effects of organizational culture on projects, in particular project culture and project management style. Methodology/approach: descriptive and explorative; through students’ groups. Findings: the cultural relationship between organizations, their projects

  4. Evaluation of Project Achievements in VOMARE -project

    OpenAIRE

    Kokkarinen, Eeva

    2011-01-01

    The purpose of the thesis is to study the achievements of VOMARE –project from the Finnish Lifeboat Institutions perspective. The organisation is a roof organisation for voluntary maritime rescue operation in Finland. The Finnish Lifeboat Institution is a lead partner in VOMARE –project which is EU funded project and the aim of the project is to start voluntary rescue operations in Estonia. The theoretical part of the work is divided into two main categories; project management and planni...

  5. Representing Young Children with Disabilities in Classroom Environments.

    Science.gov (United States)

    Favazza, Paddy C.; LaRoe, Joyce; Phillipsen, Leslie; Kumar, Poonam

    2000-01-01

    The "Inventory of Disability Representation" was administered to 92 teachers representing kindergarten, community child care, or preschool settings. Low scores across settings indicated that classrooms typically do not have materials that represent or depict children with diverse abilities. Reasons cited by teachers are noted as are benefits…

  6. 19 CFR 146.2 - Port director as Board representative.

    Science.gov (United States)

    2010-04-01

    ...; DEPARTMENT OF THE TREASURY (CONTINUED) FOREIGN TRADE ZONES General Provisions § 146.2 Port director as Board representative. The appropriate port director shall be in charge of the zone as the representative of the Board. [T.D. 86-16, 51 FR 5049, Feb. 11, 1986, as amended by T.D. 99-27, 64 FR 13676, Mar. 22, 1999] ...

  7. 40 CFR 60.4114 - Objections concerning Hg designated representative.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Objections concerning Hg designated... Times for Coal-Fired Electric Steam Generating Units Hg Designated Representative for Hg Budget Sources § 60.4114 Objections concerning Hg designated representative. (a) Once a complete certificate of...

  8. 37 CFR 10.84 - Representing a client zealously.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Representing a client... Office Code of Professional Responsibility § 10.84 Representing a client zealously. (a) A practitioner shall not intentionally: (1) Fail to seek the lawful objectives of a client through reasonably available...

  9. 40 CFR Appendix I to Part 261 - Representative Sampling Methods

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Representative Sampling Methods I...—Representative Sampling Methods The methods and equipment used for sampling waste materials will vary with the form and consistency of the waste materials to be sampled. Samples collected using the sampling...

  10. 27 CFR 71.31 - Attorneys and other representatives.

    Science.gov (United States)

    2010-04-01

    ... representatives. 71.31 Section 71.31 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... applicant may be represented by an attorney, certified public accountant, or other person enrolled to practice before the Alcohol and Tobacco Tax and Trade Bureau under 31 CFR part 8—Practice before the...

  11. Calls to Teen Line: Representative Concerns of Adolescents.

    Science.gov (United States)

    Boehm, Kathryn E.; Schondel, Connie K.; Ivoska, William J.; Marlowe, Alison L.; Manke-Mitchell, Laurie

    1998-01-01

    Study examines whether the concerns of teenagers calling a peer listening service are representative of the concerns of teenagers in the area served. Results indicate that students' biggest concerns involve family problems, peer relationships, self-esteem, and school problems. Concludes that calls to the teen line are representative. (Author/GCP)

  12. Canadian fusion fuels technology project

    International Nuclear Information System (INIS)

    1986-01-01

    The Canadian Fusion Fuels Technology Project was launched in 1982 to coordinate Canada's provision of fusion fuels technology to international fusion power development programs. The project has a mandate to extend and adapt existing Canadian tritium technologies for use in international fusion power development programs. 1985-86 represents the fourth year of the first five-year term of the Canadian Fusion Fuels Technology Project (CFFTP). This reporting period coincides with an increasing trend in global fusion R and D to direct more effort towards the management of tritium. This has resulted in an increased linking of CFFTP activities and objectives with those of facilities abroad. In this way there has been a continuing achievement resulting from CFFTP efforts to have cooperative R and D and service activities with organizations abroad. All of this is aided by the cooperative international atmosphere within the fusion community. This report summarizes our past year and provides some highlights of the upcoming year 1986/87, which is the final year of the first five-year phase of the program. AECL (representing the Federal Government), the Ministry of Energy (representing Ontario) and Ontario Hydro, have given formal indication of their intent to continue with a second five-year program. Plans for the second phase will continue to emphasize tritium technology and remote handling

  13. The international hydrocoin project

    International Nuclear Information System (INIS)

    1988-01-01

    The international co-operation project HYDROCOIN for studying groundwater flow modelling in the context of radioactive waste disposal was initiated in 1984. Thirteen organizations from ten countries and two international organizations participate in the project which is managed by the Swedish Nuclear Power Inspectorate SKI. This report summarizes the results from the first phase of HYDROCOIN. Level 1, which has been devoted to verification of 29 computer programs for groundwater hydrology. This has been done by applying the codes to seven hypothetical test cases representing different physical situations. For linear test cases, the agreement between results calculated with different codes has been satisfactory for primarily calculated entities (groundwater pressure, salt concentration and temperatures). Results for properties derived from gradients of the primary field (groundwater velocity and trajectories) show agreement to a lesser extent. Furthermore, HYDROCOIN Level 1 illustrates problems related to solving strongly non-linear cases, such as coupled flow and brine transport. HYDROCOIN Level 1 has provided an efficient means for testing strengths and weaknesses of various strategies for groundwater flow modelling and post processing. As a result of the Level 1 effort, several code enhancements have been made

  14. The central Iowa project.

    Science.gov (United States)

    Allen, H M

    1994-10-01

    This project developed and tested a population-based survey, the HS Form, to examine health and health care in the Central Iowa community. Data from this new collection of proven sets of items were used to compare competing health plans, doctor offices, hospitals, and to develop preliminary norms of the community's insured, in two areas: system performance and health burden. The results showed that the survey: (1) was both feasible and efficient in delivering a comprehensive and generic assessment of consumers and patients; (2) revealed consistent, noteworthy differences between plans and between providers across both sets of criteria; and (3) indicated that there is substantial room for improvement in Central Iowa's health care delivery system from the public's perspective. Recommendations for next steps include: (1) following through on the June 1993 community forum (held to discuss the project's methods and results with local decision makers); (2) broadening the evaluation design to increase sample representativeness; and (3) implementing a pre/post approach to measure changes in plan and provider performance.

  15. Ethiopian flora project

    Directory of Open Access Journals (Sweden)

    O. Hedberg

    1983-11-01

    Full Text Available After thorough planning, an Ethiopian Flora Project has recently been initiated, financed by the Ethiopian Science and Technology Commission from a Swedish grant. The planning was effected by a working group including representatives of the Biology Department at Addis Ababa University and the Institute of Systematic Botany in Uppsala as well as some international experts selected by AETFAT, and was finalized by an Ethiopian Flora Committee. The project leader is Professor Tewolde Berhan G. Egziabher in Addis Ababa, assisted by an Ethiopian secretariat under the Director of the National Herbarium. A European counterpart secretariat, headed by the author, has also been organized with Dr I. Hedberg as co-ordinator. Collecting expeditions to insufficiently known areas, loans from the Addis Ababa Herbarium to collaborating taxonomists, and other activities inside Ethiopia are organized by the Ethiopian secretariat, whereas the Uppsala secretariat is responsible for the initiation and co-ordination of the taxonomic revisions and family accounts needed for the Flora. Collaborators for several of the roughly 200 families of Ethiopian vascular plants have already been secured, but many more remain to be covered. AETFAT members with specialist knowledge of the remaining families are requested to help fill the gaps in our list of contributors.

  16. Time Overrun in Construction Project

    Science.gov (United States)

    Othman, I.; Shafiq, Nasir; Nuruddin, M. F.

    2017-12-01

    Timely completion is the key criteria to achieve success in any project despite the industry. Unfortunately construction industry in Malaysia has been labelled as industry facing poor performance leading to failure in achieving effective time management. As the consequence most of the project face huge amount of time overrun. This study assesses the causes of construction projects time overrun in Malaysia using structured questionnaire survey. Each respondent is asked to assign a one-to-five rating for each of the 18 time factors identified from literature review. Out of the 50 questionnaires sent out, 33 were received back representing 68% of the response rate. Data received from the questionnaires were analysed and processed using the descriptive statistics procedures. Findings from the study revealed that design and documentation issues, project management and contract administration, ineffective project planning and scheduling, contractor’s site management, financial resource management were the major factors that cause the time overrun. This study is hoped to help the practitioners to implement the mitigation measure at planning stage in order to achieve successful construction projects.

  17. THE VALUE OF THE PROJECT, ITS HISTORICAL CONTEXT AND MEANINGFUL

    Directory of Open Access Journals (Sweden)

    Anastasiia Liezina

    2017-03-01

    Full Text Available In the article the historical stages of the category of “value” in various sciences, particularly in project management were considered. Chronology of evolutionary change and borrowing the term “value” in various sciences was developed. Existing approaches to determining the value of project management were analyzed. Author's interpretation of value projects was represented. Author's vision “iron” triangle of project management criteria based on the transformation of the classical approach was represented. Substance of the value of projects, taking into account the interests of all stakeholders, in terms of their value expectations was revealed. Key words: value, project management, project value, project stakeholders, the criteria for success of the project, “Iron” triangle.

  18. The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project

    Science.gov (United States)

    Lawrence N. Hudson; Joseph Wunderle M.; And Others

    2016-01-01

    The PREDICTS project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)—has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to...

  19. The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project

    NARCIS (Netherlands)

    Hudson, Lawrence N; Newbold, Tim; Contu, Sara; Hill, Samantha L L; Lysenko, Igor; De Palma, Adriana; Phillips, Helen R P; Alhusseini, Tamera I; Bedford, Felicity E; Bennett, Dominic J; Booth, Hollie; Burton, Victoria J; Chng, Charlotte W T; Choimes, Argyrios; Correia, David L P; Day, Julie; Echeverría-Londoño, Susy; Emerson, Susan R; Gao, Di; Garon, Morgan; Harrison, Michelle L K; Ingram, Daniel J; Jung, Martin; Kemp, Victoria; Kirkpatrick, Lucinda; Martin, Callum D; Pan, Yuan; Pask-Hale, Gwilym D; Pynegar, Edwin L; Robinson, Alexandra N; Sanchez-Ortiz, Katia; Senior, Rebecca A; Simmons, Benno I; White, Hannah J; Zhang, Hanbin; Aben, Job; Abrahamczyk, Stefan; Adum, Gilbert B; Aguilar-Barquero, Virginia; Aizen, Marcelo A; Albertos, Belén; Alcala, E L; Del Mar Alguacil, Maria; Alignier, Audrey; Ancrenaz, Marc; Andersen, Alan N; Arbeláez-Cortés, Enrique; Armbrecht, Inge; Arroyo-Rodríguez, Víctor; Aumann, Tom; Axmacher, Jan C; Azhar, Badrul; Azpiroz, Adrián B; Baeten, Lander; Bakayoko, Adama; Báldi, András; Banks, John E; Baral, Sharad K; Barlow, Jos; Barratt, Barbara I P; Barrico, Lurdes; Bartolommei, Paola; Barton, Diane M; Basset, Yves; Batáry, Péter; Bates, Adam J; Baur, Bruno; Bayne, Erin M; Beja, Pedro; Benedick, Suzan; Berg, Åke; Bernard, Henry; Berry, Nicholas J; Bhatt, Dinesh; Bicknell, Jake E; Bihn, Jochen H; Blake, Robin J; Bobo, Kadiri S; Bóçon, Roberto; Boekhout, Teun; Böhning-Gaese, Katrin; Bonham, Kevin J; Borges, Paulo A V; Borges, Sérgio H; Boutin, Céline; Bouyer, Jérémy; Bragagnolo, Cibele; Brandt, Jodi S; Brearley, Francis Q; Brito, Isabel; Bros, Vicenç; Brunet, Jörg; Buczkowski, Grzegorz; Buddle, Christopher M; Bugter, Rob; Buscardo, Erika; Buse, Jörn; Cabra-García, Jimmy; Cáceres, Nilton C; Cagle, Nicolette L; Calviño-Cancela, María; Cameron, Sydney A; Cancello, Eliana M; Caparrós, Rut; Cardoso, Pedro; Carpenter, Dan; Carrijo, Tiago F; Carvalho, Anelena L; Cassano, Camila R; Castro, Helena; Castro-Luna, Alejandro A; Rolando, Cerda B; Cerezo, Alexis; Chapman, Kim Alan; Chauvat, Matthieu; Christensen, Morten; Clarke, Francis M; Cleary, Daniel F R; Colombo, Giorgio; Connop, Stuart P; Craig, Michael D; Cruz-López, Leopoldo; Cunningham, Saul A; D'Aniello, Biagio; D'Cruze, Neil; da Silva, Pedro Giovâni; Dallimer, Martin; Danquah, Emmanuel; Darvill, Ben; Dauber, Jens; Davis, Adrian L V; Dawson, Jeff; de Sassi, Claudio; de Thoisy, Benoit; Deheuvels, Olivier; Dejean, Alain; Devineau, Jean-Louis; Diekötter, Tim; Dolia, Jignasu V; Domínguez, Erwin; Dominguez-Haydar, Yamileth; Dorn, Silvia; Draper, Isabel; Dreber, Niels; Dumont, Bertrand; Dures, Simon G; Dynesius, Mats; Edenius, Lars; Eggleton, Paul; Eigenbrod, Felix; Elek, Zoltán; Entling, Martin H; Esler, Karen J; de Lima, Ricardo F; Faruk, Aisyah; Farwig, Nina; Fayle, Tom M; Felicioli, Antonio; Felton, Annika M; Fensham, Roderick J; Fernandez, Ignacio C; Ferreira, Catarina C; Ficetola, Gentile F; Fiera, Cristina; Filgueiras, Bruno K C; Fırıncıoğlu, Hüseyin K; Flaspohler, David; Floren, Andreas; Fonte, Steven J; Fournier, Anne; Fowler, Robert E; Franzén, Markus; Fraser, Lauchlan H; Fredriksson, Gabriella M; Freire, Geraldo B; Frizzo, Tiago L M; Fukuda, Daisuke; Furlani, Dario; Gaigher, René; Ganzhorn, Jörg U; García, Karla P; Garcia-R, Juan C; Garden, Jenni G; Garilleti, Ricardo; Ge, Bao-Ming; Gendreau-Berthiaume, Benoit; Gerard, Philippa J; Gheler-Costa, Carla; Gilbert, Benjamin; Giordani, Paolo; Giordano, Simonetta; Golodets, Carly; Gomes, Laurens G L; Gould, Rachelle K; Goulson, Dave; Gove, Aaron D; Granjon, Laurent; Grass, Ingo; Gray, Claudia L; Grogan, James; Gu, Weibin; Guardiola, Moisès; Gunawardene, Nihara R; Gutierrez, Alvaro G; Gutiérrez-Lamus, Doris L; Haarmeyer, Daniela H; Hanley, Mick E; Hanson, Thor; Hashim, Nor R; Hassan, Shombe N; Hatfield, Richard G; Hawes, Joseph E; Hayward, Matt W; Hébert, Christian; Helden, Alvin J; Henden, John-André; Henschel, Philipp; Hernández, Lionel; Herrera, James P; Herrmann, Farina; Herzog, Felix; Higuera-Diaz, Diego; Hilje, Branko; Höfer, Hubert; Hoffmann, Anke; Horgan, Finbarr G; Hornung, Elisabeth; Horváth, Roland; Hylander, Kristoffer; Isaacs-Cubides, Paola; Ishida, Hiroaki; Ishitani, Masahiro; Jacobs, Carmen T; Jaramillo, Víctor J; Jauker, Birgit; Hernández, F Jiménez; Johnson, McKenzie F; Jolli, Virat; Jonsell, Mats; Juliani, S Nur; Jung, Thomas S; Kapoor, Vena; Kappes, Heike; Kati, Vassiliki; Katovai, Eric; Kellner, Klaus; Kessler, Michael; Kirby, Kathryn R; Kittle, Andrew M; Knight, Mairi E; Knop, Eva; Kohler, Florian; Koivula, Matti; Kolb, Annette; Kone, Mouhamadou; Kőrösi, Ádám; Krauss, Jochen; Kumar, Ajith; Kumar, Raman; Kurz, David J; Kutt, Alex S; Lachat, Thibault; Lantschner, Victoria; Lara, Francisco; Lasky, Jesse R; Latta, Steven C; Laurance, William F; Lavelle, Patrick; Le Féon, Violette; LeBuhn, Gretchen; Légaré, Jean-Philippe; Lehouck, Valérie; Lencinas, María V; Lentini, Pia E; Letcher, Susan G; Li, Qi; Litchwark, Simon A; Littlewood, Nick A; Liu, Yunhui; Lo-Man-Hung, Nancy; López-Quintero, Carlos A; Louhaichi, Mounir; Lövei, Gabor L; Lucas-Borja, Manuel Esteban; Luja, Victor H; Luskin, Matthew S; MacSwiney G, M Cristina; Maeto, Kaoru; Magura, Tibor; Mallari, Neil Aldrin; Malone, Louise A; Malonza, Patrick K; Malumbres-Olarte, Jagoba; Mandujano, Salvador; Måren, Inger E; Marin-Spiotta, Erika; Marsh, Charles J; Marshall, E J P; Martínez, Eliana; Martínez Pastur, Guillermo; Moreno Mateos, David; Mayfield, Margaret M; Mazimpaka, Vicente; McCarthy, Jennifer L; McCarthy, Kyle P; McFrederick, Quinn S; McNamara, Sean; Medina, Nagore G; Medina, Rafael; Mena, Jose L; Mico, Estefania; Mikusinski, Grzegorz; Milder, Jeffrey C; Miller, James R; Miranda-Esquivel, Daniel R; Moir, Melinda L; Morales, Carolina L; Muchane, Mary N; Muchane, Muchai; Mudri-Stojnic, Sonja; Munira, A Nur; Muoñz-Alonso, Antonio; Munyekenye, B F; Naidoo, Robin; Naithani, A; Nakagawa, Michiko; Nakamura, Akihiro; Nakashima, Yoshihiro; Naoe, Shoji; Nates-Parra, Guiomar; Navarrete Gutierrez, Dario A; Navarro-Iriarte, Luis; Ndang'ang'a, Paul K; Neuschulz, Eike L; Ngai, Jacqueline T; Nicolas, Violaine; Nilsson, Sven G; Noreika, Norbertas; Norfolk, Olivia; Noriega, Jorge Ari; Norton, David A; Nöske, Nicole M; Nowakowski, A Justin; Numa, Catherine; O'Dea, Niall; O'Farrell, Patrick J; Oduro, William; Oertli, Sabine; Ofori-Boateng, Caleb; Oke, Christopher Omamoke; Oostra, Vicencio; Osgathorpe, Lynne M; Otavo, Samuel Eduardo; Page, Navendu V; Paritsis, Juan; Parra-H, Alejandro; Parry, Luke; Pe'er, Guy; Pearman, Peter B; Pelegrin, Nicolás; Pélissier, Raphaël; Peres, Carlos A; Peri, Pablo L; Persson, Anna S; Petanidou, Theodora; Peters, Marcell K; Pethiyagoda, Rohan S; Phalan, Ben; Philips, T Keith; Pillsbury, Finn C; Pincheira-Ulbrich, Jimmy; Pineda, Eduardo; Pino, Joan; Pizarro-Araya, Jaime; Plumptre, A J; Poggio, Santiago L; Politi, Natalia; Pons, Pere; Poveda, Katja; Power, Eileen F; Presley, Steven J; Proença, Vânia; Quaranta, Marino; Quintero, Carolina; Rader, Romina; Ramesh, B R; Ramirez-Pinilla, Martha P; Ranganathan, Jai; Rasmussen, Claus; Redpath-Downing, Nicola A; Reid, J Leighton; Reis, Yana T; Rey Benayas, José M; Rey-Velasco, Juan Carlos; Reynolds, Chevonne; Ribeiro, Danilo Bandini; Richards, Miriam H; Richardson, Barbara A; Richardson, Michael J; Ríos, Rodrigo Macip; Robinson, Richard; Robles, Carolina A; Römbke, Jörg; Romero-Duque, Luz Piedad; Rös, Matthias; Rosselli, Loreta; Rossiter, Stephen J; Roth, Dana S; Roulston, T'ai H; Rousseau, Laurent; Rubio, André V; Ruel, Jean-Claude; Sadler, Jonathan P; Sáfián, Szabolcs; Saldaña-Vázquez, Romeo A; Sam, Katerina; Samnegård, Ulrika; Santana, Joana; Santos, Xavier; Savage, Jade; Schellhorn, Nancy A; Schilthuizen, Menno; Schmiedel, Ute; Schmitt, Christine B; Schon, Nicole L; Schüepp, Christof; Schumann, Katharina; Schweiger, Oliver; Scott, Dawn M; Scott, Kenneth A; Sedlock, Jodi L; Seefeldt, Steven S; Shahabuddin, Ghazala; Shannon, Graeme; Sheil, Douglas; Sheldon, Frederick H; Shochat, Eyal; Siebert, Stefan J; Silva, Fernando A B; Simonetti, Javier A; Slade, Eleanor M; Smith, Jo; Smith-Pardo, Allan H; Sodhi, Navjot S; Somarriba, Eduardo J; Sosa, Ramón A; Soto Quiroga, Grimaldo; St-Laurent, Martin-Hugues; Starzomski, Brian M; Stefanescu, Constanti; Steffan-Dewenter, Ingolf; Stouffer, Philip C; Stout, Jane C; Strauch, Ayron M; Struebig, Matthew J; Su, Zhimin; Suarez-Rubio, Marcela; Sugiura, Shinji; Summerville, Keith S; Sung, Yik-Hei; Sutrisno, Hari; Svenning, Jens-Christian; Teder, Tiit; Threlfall, Caragh G; Tiitsaar, Anu; Todd, Jacqui H; Tonietto, Rebecca K; Torre, Ignasi; Tóthmérész, Béla; Tscharntke, Teja; Turner, Edgar C; Tylianakis, Jason M; Uehara-Prado, Marcio; Urbina-Cardona, Nicolas; Vallan, Denis; Vanbergen, Adam J; Vasconcelos, Heraldo L; Vassilev, Kiril; Verboven, Hans A F; Verdasca, Maria João; Verdú, José R; Vergara, Carlos H; Vergara, Pablo M; Verhulst, Jort; Virgilio, Massimiliano; Vu, Lien Van; Waite, Edward M; Walker, Tony R; Wang, Hua-Feng; Wang, Yanping; Watling, James I; Weller, Britta; Wells, Konstans; Westphal, Catrin; Wiafe, Edward D; Williams, Christopher D; Willig, Michael R; Woinarski, John C Z; Wolf, Jan H D; Wolters, Volkmar; Woodcock, Ben A; Wu, Jihua; Wunderle, Joseph M; Yamaura, Yuichi; Yoshikura, Satoko; Yu, Douglas W; Zaitsev, Andrey S; Zeidler, Juliane; Zou, Fasheng; Collen, Ben; Ewers, Rob M; Mace, Georgina M; Purves, Drew W; Scharlemann, Jörn P W; Purvis, Andy

    The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of

  20. The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project

    DEFF Research Database (Denmark)

    Hudson, Lawrence N; Newbold, Tim; Contu, Sara

    2017-01-01

    The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity ...

  1. Energy projections 1979

    International Nuclear Information System (INIS)

    1979-01-01

    The projections, prepared by Department of Energy officials, examine possible UK energy demand and supply prospects to the end of the century. They are based on certain broad long term assumptions about economic growth, technical improvements and movements in energy prices. The projections are intended to provide a broad quantitative framework for the consideration of possible energy futures and policy choices. Two cases are considered. In the first, the UK economy is assumed to grow at about 3 per cent to the end of the century and, in the second, at a lower level of about 2 per cent per annum. In both it is assumed that world oil prices will rise significantly above present levels (reaching some 30 dollars a barrel in terms of 1977 prices for Saudi Arabian marker crude by the end of the century). After incorporation of allowances for energy conservation which approximate to a reduction of some 20 per cent in demand, total primary fuel requirements in the year 2000 are estimated in the range 445 to 510 million tonnes of coal equivalent (mtce), representing an average rate of growth of 0.9 to 1.5 per cent a year. Potential indigenous energy supply by the end of the century is estimated in the range 390 to 410 mtce. This includes a possible installed nuclear capacity of up to 40 Gigawatts, approximately a fourfold increase on capacity already installed or under construction, and indigenous coal production of up to 155 million tonnes a year. The projections highlight the UK's prospective emergence during the later part of the century from a period from 1980 of energy surplus and the increasing roles which energy conservation, nuclear power and coal will be called upon to play as oil becomes scarcer and more expensive in the international market and as indigenous oil and gas production declines. (author)

  2. Integrated project management type contracts

    International Nuclear Information System (INIS)

    Heisler, S.I.

    1975-01-01

    The concept of integrated project management represents a single source to which the owner can turn for all project management functions excepting for those relating to outside parties such as site purchase, personnel selection etc. Other functions such as design, procurement, construction management, schedule and cost control, quality assurance/quality control are usually handled by the integrated project manager as the agent of the owner. The arrangement is flexible and the responsibilities can be varied to suit the size and experience of the owner. Past experience in the United States indicates an increase in the trend toward IPM work and it appears that overseas this trend is developing also. (orig./RW) [de

  3. A transportation-scheduling system for managing silvicultural projects

    Science.gov (United States)

    Jorge F. Valenzuela; H. Hakan Balci; Timothy McDonald

    2005-01-01

    A silvicultural project encompasses tasks such as sitelevel planning, regeneration, harvestin, and stand-tending treatments. an essential problem in managing silvicultural projects is to efficiently schedule the operations while considering project task due dates and costs of moving scarce resources to specific job locations. Transportation costs represent a...

  4. The Importance of Investment Decisions in Project Management

    Directory of Open Access Journals (Sweden)

    Cosmina Mădălina Pop

    2008-10-01

    Full Text Available The financing decision alongside with investment decision represents the core of financial management. The paper presents the main steps in realizing investment projects, the option criteria used in pre-investment analysis, the techniques of financing the investments project, but also the methods of evaluation applied in selecting the most suitable project, accordingly with company’s developlment strategy and policy.

  5. Searches over graphs representing geospatial-temporal remote sensing data

    Science.gov (United States)

    Brost, Randolph; Perkins, David Nikolaus

    2018-03-06

    Various technologies pertaining to identifying objects of interest in remote sensing images by searching over geospatial-temporal graph representations are described herein. Graphs are constructed by representing objects in remote sensing images as nodes, and connecting nodes with undirected edges representing either distance or adjacency relationships between objects and directed edges representing changes in time. Geospatial-temporal graph searches are made computationally efficient by taking advantage of characteristics of geospatial-temporal data in remote sensing images through the application of various graph search techniques.

  6. Planning "and" Sprinting: Use of a Hybrid Project Management Methodology within a CIS Capstone Course

    Science.gov (United States)

    Baird, Aaron; Riggins, Frederick J.

    2012-01-01

    An increasing number of information systems projects in industry are managed using hybrid project management methodologies, but this shift in project management methods is not fully represented in our CIS curriculums. CIS capstone courses often include an applied project that is managed with traditional project management methods (plan first,…

  7. Managing projects using a project management approach

    Directory of Open Access Journals (Sweden)

    Marko D. Andrejić

    2011-04-01

    Full Text Available Modern management theory treats all complex tasks and duties like projects and make these projects possible to be managed by a particular organizational-management concept in order to achieve a goal effectively. A large number of jobs and tasks performed in the system of defense or for defense purposes have the characteristics of projects. Project management is both a skill and a science of monitoring human, material, financial, energy and other resources to achieve required objectives within the given limits: deadlines, time, budget, possibility of realization and the satisfaction of the interests of all project participants. Project management is a traditional area of applied (or functional management focused on managing complex and uncertain situations with defined goals. Introduction In conditions of rapid change and high uncertainty, only adaptive organizations survive, i. e. those that are able not only to react quickly to changes but also to proactively take advantage of changes. Development of project management The biggest influence on the development of the area had complex jobs within the engineering profession. In parallel with the traditional approach new approaches began to develop, while the traditional one still remained in use. Contrary to the traditional engineering approach, a dynamic model first developed in order to respond to demands for greater control of costs. Project management Project management is a skill and knowledge of human and material resources to achieve set objectives within prescribed limits: deadlines, time, budget, possibility of realization, and the satisfaction of all participants in the project. In order to realize a project effectively, it is necessary to manage it rationally. Planning and project management A project plan is a document that allows all team members insight on where to go, when to start and when to arrive, what is necessary to be done in order to achieve the project objectives and what

  8. Graphical User Interface Development for Representing Air Flow Patterns

    Science.gov (United States)

    Chaudhary, Nilika

    2004-01-01

    In the Turbine Branch, scientists carry out experimental and computational work to advance the efficiency and diminish the noise production of jet engine turbines. One way to do this is by decreasing the heat that the turbine blades receive. Most of the experimental work is carried out by taking a single turbine blade and analyzing the air flow patterns around it, because this data indicates the sections of the turbine blade that are getting too hot. Since the cost of doing turbine blade air flow experiments is very high, researchers try to do computational work that fits the experimental data. The goal of computational fluid dynamics is for scientists to find a numerical way to predict the complex flow patterns around different turbine blades without physically having to perform tests or costly experiments. When visualizing flow patterns, scientists need a way to represent the flow conditions around a turbine blade. A researcher will assign specific zones that surround the turbine blade. In a two-dimensional view, the zones are usually quadrilaterals. The next step is to assign boundary conditions which define how the flow enters or exits one side of a zone. way of setting up computational zones and grids, visualizing flow patterns, and storing all the flow conditions in a file on the computer for future computation. Such a program is necessary because the only method for creating flow pattern graphs is by hand, which is tedious and time-consuming. By using a computer program to create the zones and grids, the graph would be faster to make and easier to edit. Basically, the user would run a program that is an editable graph. The user could click and drag with the mouse to form various zones and grids, then edit the locations of these grids, add flow and boundary conditions, and finally save the graph for future use and analysis. My goal this summer is to create a graphical user interface (GUI) that incorporates all of these elements. I am writing the program in

  9. Life forms of succulent representatives of the family Asclepiadaceae

    Directory of Open Access Journals (Sweden)

    Marina Gaidarzhy

    2013-04-01

    Full Text Available The life forms of succulent’s representatives of the family Asclepiadaceae of the tropical and subtropical plants from the collection of O.V. Fomin Botanical garden according to author classification are characterized.

  10. The value of political parties to representative democracy

    NARCIS (Netherlands)

    Kölln, Ann-Kristin

    2015-01-01

    Political parties play a major role in democratic processes around the world. Recent empirical research suggests that parties are increasingly less important to citizens. Simultaneously, classic and contemporary theories of representative democracy specifically still minimally incorporate accounts

  11. Microalbuminuria represents a feature of advanced renal disease in ...

    African Journals Online (AJOL)

    . The systematic screening for microalbuminuria represents the touchstone to prevent CRF in patients with diabetes mellitus. Microalbuminuria has also been demonstrated in patients with sickle cell disease. Whether this has the same ...

  12. Developing Representative Michigan Truck Configurations for Bridge Load Rating

    Science.gov (United States)

    2018-02-28

    The objective of this study is to recommend a rating process representative of Michigan load effects for legal and extended permit vehicles. For this study, high fidelity WIM data from 20 Michigan sites were analyzed. Using vehicle weight and configu...

  13. UN: new Permanent Representative of Monaco presents credentials

    CERN Multimedia

    2003-01-01

    "Michel Borghini, the new Permanent Representative of Monaco to the United Nations, presented his credentials to Secretary-General Kofi Annan today. He worked as a researcher at CERN from 1965 to 1969" (1/3 page).

  14. On the Representativeness of Norming Samples for Aptitude Test

    National Research Council Canada - National Science Library

    Sims, William

    2003-01-01

    ...). We regressed aptitude test scores on demographics and concluded that: ̂ Norming sample for aptitude tests must be representative of the target population with respect to age, race"ethnicity, gender, respondent's education, and mother's...

  15. Sample representativeness verification of the FADN CZ farm business sample

    Directory of Open Access Journals (Sweden)

    Marie Prášilová

    2011-01-01

    Full Text Available Sample representativeness verification is one of the key stages of statistical work. After having joined the European Union the Czech Republic joined also the Farm Accountancy Data Network system of the Union. This is a sample of bodies and companies doing business in agriculture. Detailed production and economic data on the results of farming business are collected from that sample annually and results for the entire population of the country´s farms are then estimated and assessed. It is important hence, that the sample be representative. Representativeness is to be assessed as to the number of farms included in the survey and also as to the degree of accordance of the measures and indices as related to the population. The paper deals with the special statistical techniques and methods of the FADN CZ sample representativeness verification including the necessary sample size statement procedure. The Czech farm population data have been obtained from the Czech Statistical Office data bank.

  16. Arab Knowledge Society: Who Represents the Arab World Online ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Arab Knowledge Society: Who Represents the Arab World Online? ... Wikipedia's culture of openness, extensive reuse and near ubiquity makes it an ideal place to ... IWRA/IDRC webinar on climate change and adaptive water management.

  17. Elections for staff representatives – Join, commit and vote!

    CERN Multimedia

    Staff Association

    2015-01-01

    The Staff Council is a statutory body representing collectively in the area of employment conditions all CERN staff members (MPE and MPA), as well as the pensioners, former Cernois. The Staff Council is the supreme representative body of the CERN staff and pensioners, which defines the main lines of the policy of the Staff Association. The Staff Council is composed of staff representatives (45 seats to represent staff members, and 5 for representing fellows and associate members), as well as delegates for pensioners (seven positions), designated by GAC-EPA. Every two years, the Council is renewed through elections. Concerning the 45 delegates representing staff members, all departments have a least two seats allocated, one in career paths AA to D and one in career paths E to H. This guarantees a fair distribution of seats among the various organizational units and career paths. The table below, shows the exact number of delegates per department and career paths. Staff members or fellows who want to participa...

  18. Storytelling in Projects

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas; Andersen, Peter Bøgh

    2006-01-01

    project managers should not only be concerned with project plans, but also with project stories. In this paper we explore some basic principles for transforming project plans into appealing stories. We discuss what may happen to stories once they are released into public space. And we illustrate how......Plans and stories are two different ways of communicating about projects. Project plans are formalized descriptions, primarily supporting coordination. Project stories are accounts whose primary function is emotional appeal. Project stories influence the projects’ chances of success. Therefore...... the possibilities of telling favorable stories may have repercussions on the project planning....

  19. Eastern slopes grizzly bear project : project update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-01-01

    This report updates a study to examine the cumulative effects of human activities on the grizzly bears in the central Canadian Rockies. The project was initiated in 1994 to acquire accurate scientific information on the habitat and populations of grizzly bears in the area of the Banff National Park and Kananaskis Country. This area is probably the most heavily used and developed area where the grizzly still survives. The information gathered throughout the course of the study is used to better protect and manage the bears and other sensitive carnivores in the region. Using telemetry, researchers monitored 25 grizzly bears which were radio-collared in a 22,000 square-kilometer area in the upper Bow Valley drainage of the eastern Alberta slopes. The researchers worked with representatives from Husky Oil and Rigel Energy on the development of the Moose Mountain oil and gas field without adversely affecting the grizzly bear population. Information collected over eight years indicates that the grizzly bears have few and infrequent offspring. Using the information gathered thus far, the location of the Moose Mountain to Jumping Pound pipeline was carefully selected, since the bears suffer from high mortality, and the food and cover had already been compromised by the high number of roads, trails and other human activities in the area. The research concluded in November 2001 provides sufficient information to accurately asses the status of the grizzly bear population and habitat. The data will be analyzed and integrated in 2002 into models that reflect the variables affecting grizzly bears and a final report will be published.

  20. The Ethiopian Flora Project

    DEFF Research Database (Denmark)

    Demissew, Sebsebe; Brochmann, Christian; Kelbessa, Ensermu

    2011-01-01

    The account reviews and analyses the scietific projects derived from activities in connection with the Ethiopian Flora Project, including the [Ethiopian] Monocot Project, the Afro-alpine "Sky-island" project, the Vegetation and Ecological Conditions of Plantations Project, the Fire Ecology Projec...

  1. Capital projects coordination

    Directory of Open Access Journals (Sweden)

    Zubović Jovan

    2004-01-01

    Full Text Available This paper looks at the difficulties of managing modem capital projects and endeavors to reduce the complexities to simpler and more understandable terms. It examines the project environment, defines project management and discusses points of difference from traditional management. In the second part of the paper are presented fundamentals for project success for different types of projects.

  2. From project management to project leadership

    NARCIS (Netherlands)

    Braun, F.; Avital, M.

    2010-01-01

    It is virtually a truism that good leadership practices can help project managers with attaining the desired project outcome. However, a better understanding of which leadership practices enable project managers to be more effective warrants further investigation. Subsequently, in this study, we

  3. An IS Project Management Course Project

    Science.gov (United States)

    Frank, Ronald L.

    2010-01-01

    Information Systems curricula should provide project management (PM) theory, current practice, and hands-on experience. The schedule usually does not allow time in Analysis and Design courses for development oriented project management instruction other than a short introduction. Similarly, networking courses usually don't put project management…

  4. Managing Projects for Change: Contextualised Project Management

    Science.gov (United States)

    Tynan, Belinda; Adlington, Rachael; Stewart, Cherry; Vale, Deborah; Sims, Rod; Shanahan, Peter

    2010-01-01

    This paper will detail three projects which focussed on enhancing online learning at a large Australian distance education University within a School of Business, School of Health and School of Education. Each project had special funding and took quite distinctive project management approaches, which reflect the desire to embed innovation and…

  5. Towards Representative Metallurgical Sampling and Gold Recovery Testwork Programmes

    Directory of Open Access Journals (Sweden)

    Simon C. Dominy

    2018-05-01

    Full Text Available When developing a process flowsheet, the risks in achieving positive financial outcomes are minimised by ensuring representative metallurgical samples and high quality testwork. The quality and type of samples used are as important as the testwork itself. The key characteristic required of any set of samples is that they represent a given domain and quantify its variability. There are those who think that stating a sample(s is representative makes it representative without justification. There is a need to consider both (1 in-situ and (2 testwork sub-sample representativity. Early ore/waste characterisation and domain definition are required, so that sampling and testwork protocols can be designed to suit the style of mineralisation in question. The Theory of Sampling (TOS provides an insight into the causes and magnitude of errors that may occur during the sampling of particulate materials (e.g., broken rock and is wholly applicable to metallurgical sampling. Quality assurance/quality control (QAQC is critical throughout all programmes. Metallurgical sampling and testwork should be fully integrated into geometallurgical studies. Traditional metallurgical testwork is critical for plant design and is an inherent part of geometallurgy. In a geometallurgical study, multiple spatially distributed small-scale tests are used as proxies for process parameters. These will be validated against traditional testwork results. This paper focusses on sampling and testwork for gold recovery determination. It aims to provide the reader with the background to move towards the design, implementation and reporting of representative and fit-for-purpose sampling and testwork programmes. While the paper does not intend to provide a definitive commentary, it critically assesses the hard-rock sampling methods used and their optimal collection and preparation. The need for representative sampling and quality testwork to avoid financial and intangible losses is

  6. [Administration of the "Healthy School" project].

    Science.gov (United States)

    Bjegović, V; Zivković, M; Marinković, J; Vuković, D; Legetić, B

    1996-01-01

    The term of project management is commonly used to describe the work of a team that is handling a special program. In this type of management, a form of leadership which creates environment, enables fast movement of participants through different work phases achieving the common aims, is used [1-4]. The "Healthy School" Project, launched in almost all European countries, has been taking place in Yugoslavia since the end of 1991 [5]. The project developed within the country designed as a health promotion-education intervention study in primary schools. The network of 13 schools on 11 locations representing typical economic, cultural and social environments, was established to cover the country. Although the proposed methodological approach from WHO was followed [6], the specific situation in the country (economic crisis, break down of Yugoslav Federation, the war and international blockade) distated the particular modification. The management of the Healthy School Project in general, and in Yugoslavia particularly, is based upon project management structure (Scheme 1). The objective of this research was to assess the Healthy School project management in Yugoslavia, by measuring causal, intervening and output variables. In the process of assessing the management in general, three groups of criteria are commonly used: (a) causal (those that influence the course of developments in the Project), (b) intervening (representing the current condition of the internal state of the Project), and (c) output (that reflect the Project achievements). (a) For the purpose of this study the causal criteria were measured by analyzing the overall management strategy and the level of agreement in objectives of the Project itself, the Project Coordinators and main participants in the Project. (b) The intervening criteria used in this assessment were: the time spent on different project activities, the estimate of the severity of the problems in different aspects of project management

  7. Experimental verification of air flow rate measurement for representative isokinetic air sampling in ventilation stacks

    International Nuclear Information System (INIS)

    Okruhlica, P.; Mrtvy, M.; Kopecky, Z.

    2009-01-01

    Nuclear facilities are obliged to monitor their discharge's influence on environment. Main monitored factions in NPP's ventilation stacks are usually noble gasses, particulates and iodine. These factions are monitored in air sampled from ventilation stack by means of sampling rosette and bypass followed with on-line measuring monitors and balance sampling devices with laboratory evaluations. Correct air flow rate measurement and representative iso-kinetic air sampling system is essential for physical correct and metrological accurate evaluation of discharge influence on environment. Pairs of measuring sensors (Anemometer, pressure gauge, thermometer and humidity meter) are symmetrically placed in horizontal projection of stack on positions based on measured air flow velocity distribution characteristic, Analogically diameter of sampling rosette nozzles and their placement in the middle of 6 - 7 annuluses are calculated for assurance of representative iso-kinetic sampling. (authors)

  8. Experimental verification of air flow rate measurement for representative isokinetic air sampling in ventilation stacks

    International Nuclear Information System (INIS)

    Okruhlica, P.; Mrtvy, M.; Kopecky, Z.

    2008-01-01

    Nuclear facilities are obliged to monitor their discharge's influence on environment. Main monitored factions in NPP's ventilation stacks are usually noble gasses, particulates and iodine. These factions are monitored in air sampled from ventilation stack by means of sampling rosette and bypass followed with on-line measuring monitors and balance sampling devices with laboratory evaluations. Correct air flow rate measurement and representative iso-kinetic air sampling system is essential for physical correct and metrological accurate evaluation of discharge influence on environment. Pairs of measuring sensors (Anemometer, pressure gauge, thermometer and humidity meter) are symmetrically placed in horizontal projection of stack on positions based on measured air flow velocity distribution characteristic, Analogically diameter of sampling rosette nozzles and their placement in the middle of 6- 7 annuluses are calculated for assurance of representative iso-kinetic sampling. (authors)

  9. Feasibility of using the Omaha System to represent public health nurse manager interventions.

    Science.gov (United States)

    Monsen, Karen A; Newsom, Eric T

    2011-01-01

    To test the feasibility of representing public health nurse (PHN) manager interventions using a recognized standardized nursing terminology. A nurse manager in a Midwest local public health agency documented nurse manager interventions using the Omaha System for 5 months. ANALYTIC STRATEGY: The data were analyzed and the results were compared with the results from a parallel analysis of existing PHN intervention data. Interventions for 79 "clients" (projects, teams, or individuals) captured 76% of recorded work hours, and addressed 43% of Omaha System problems. Most problems were addressed at the "community" level (87.1%) versus the "individual" level (12.9%). Nursing practice differed between the 2 knowledge domains of public health family home visiting nursing and public health nursing management. Standardized nursing terminologies have the potential to represent, describe, and quantify nurse manager interventions for future evaluation and research. © 2011 Wiley Periodicals, Inc.

  10. Balancing Design Project Supervision and Learning Facilitation

    DEFF Research Database (Denmark)

    Nielsen, Louise Møller

    2012-01-01

    experiences and expertise to guide the students’ decisions in relation to the design project. This paper focuses on project supervision in the context of design education – and more specifically on how this supervision is unfolded in a Problem Based Learning culture. The paper explores the supervisor......’s balance between the roles: 1) Design Project Supervisor – and 2) Learning Facilitator – with the aim to understand when to apply the different roles, and what to be aware of when doing so. This paper represents the first pilot-study of a larger research effort. It is based on a Lego Serious Play workshop......In design there is a long tradition for apprenticeship, as well as tradition for learning through design projects. Today many design educations are positioned within the University context, and have to be aligned with the learning culture and structure, which they represent. This raises a specific...

  11. Regional climate models' performance in representing precipitation and temperature over selected Mediterranean areas

    Directory of Open Access Journals (Sweden)

    R. Deidda

    2013-12-01

    Full Text Available This paper discusses the relative performance of several climate models in providing reliable forcing for hydrological modeling in six representative catchments in the Mediterranean region. We consider 14 Regional Climate Models (RCMs, from the EU-FP6 ENSEMBLES project, run for the A1B emission scenario on a common 0.22° (about 24 km rotated grid over Europe and the Mediterranean region. In the validation period (1951 to 2010 we consider daily precipitation and surface temperatures from the observed data fields (E-OBS data set, available from the ENSEMBLES project and the data providers in the ECA&D project. Our primary objective is to rank the 14 RCMs for each catchment and select the four best-performing ones to use as common forcing for hydrological models in the six Mediterranean basins considered in the EU-FP7 CLIMB project. Using a common suite of four RCMs for all studied catchments reduces the (epistemic uncertainty when evaluating trends and climate change impacts in the 21st century. We present and discuss the validation setting, as well as the obtained results and, in some detail, the difficulties we experienced when processing the data. In doing so we also provide useful information and advice for researchers not directly involved in climate modeling, but interested in the use of climate model outputs for hydrological modeling and, more generally, climate change impact studies in the Mediterranean region.

  12. I-15 North Project

    Science.gov (United States)

    2013-11-05

    Goals of this project were as follows: (1) Conduct a comprehensive evaluation study on Nevada's I-15 North Design Build Project; (2) Analyze project implementation with respect to construction zone rules by which the contractor had to abide; (3) Anal...

  13. Severn Barrage project. Detailed report - V. 5

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-01

    Prior to the present programme of work, the effects which a tidal power barrage would have on the region, during both construction and operation, had not been studied in detail. This volume of the Detailed Report therefore represents a significant extension of work into these aspects of the Severn Barrage Project. In the Regional Study, a number of benefits have been identified, some of which may represent net benefits nationally. The economic assessment of both regional and national benefits and costs is presented. The second part of this volume reports on the work done on the Legal Background for the Project. (author).

  14. Selection of Representative Models for Decision Analysis Under Uncertainty

    Science.gov (United States)

    Meira, Luis A. A.; Coelho, Guilherme P.; Santos, Antonio Alberto S.; Schiozer, Denis J.

    2016-03-01

    The decision-making process in oil fields includes a step of risk analysis associated with the uncertainties present in the variables of the problem. Such uncertainties lead to hundreds, even thousands, of possible scenarios that are supposed to be analyzed so an effective production strategy can be selected. Given this high number of scenarios, a technique to reduce this set to a smaller, feasible subset of representative scenarios is imperative. The selected scenarios must be representative of the original set and also free of optimistic and pessimistic bias. This paper is devoted to propose an assisted methodology to identify representative models in oil fields. To do so, first a mathematical function was developed to model the representativeness of a subset of models with respect to the full set that characterizes the problem. Then, an optimization tool was implemented to identify the representative models of any problem, considering not only the cross-plots of the main output variables, but also the risk curves and the probability distribution of the attribute-levels of the problem. The proposed technique was applied to two benchmark cases and the results, evaluated by experts in the field, indicate that the obtained solutions are richer than those identified by previously adopted manual approaches. The program bytecode is available under request.

  15. The PRINCE Project and its Applications (clone)

    OpenAIRE

    Bescos, Sylvie; Bisière, Christophe; Gailly, Pierre-Joseph; Krautter, Wolfgang

    1992-01-01

    The Esprit project Prince aims at development of an industrial Constraint Logic Programing environment based on the Prolog III language. In parallel, the current technology is being validated within the project on representative real-world examples. This paper describes the current status of the three application domains which were Selected to demonstrate the applicability and usefulness of CLP. These applications deal with industrial systems engineering, medium term banking planning and jobs...

  16. Web Project Management

    OpenAIRE

    Suralkar, Sunita; Joshi, Nilambari; Meshram, B B

    2013-01-01

    This paper describes about the need for Web project management, fundamentals of project management for web projects: what it is, why projects go wrong, and what's different about web projects. We also discuss Cost Estimation Techniques based on Size Metrics. Though Web project development is similar to traditional software development applications, the special characteristics of Web Application development requires adaption of many software engineering approaches or even development of comple...

  17. Assessing the use of cognitive heuristic representativeness in clinical reasoning.

    Science.gov (United States)

    Payne, Velma L; Crowley, Rebecca S; Crowley, Rebecca

    2008-11-06

    We performed a pilot study to investigate use of the cognitive heuristic Representativeness in clinical reasoning. We tested a set of tasks and assessments to determine whether subjects used the heuristics in reasoning, to obtain initial frequencies of heuristic use and related cognitive errors, and to collect cognitive process data using think-aloud techniques. The study investigates two aspects of the Representativeness heuristic - judging by perceived frequency and representativeness as causal beliefs. Results show that subjects apply both aspects of the heuristic during reasoning, and make errors related to misapplication of these heuristics. Subjects in this study rarely used base rates, showed significant variability in their recall of base rates, demonstrated limited ability to use provided base rates, and favored causal data in diagnosis. We conclude that the tasks and assessments we have developed provide a suitable test-bed to study the cognitive processes underlying heuristic errors.

  18. Assessing Use of Cognitive Heuristic Representativeness in Clinical Reasoning

    Science.gov (United States)

    Payne, Velma L.; Crowley, Rebecca S.

    2008-01-01

    We performed a pilot study to investigate use of the cognitive heuristic Representativeness in clinical reasoning. We tested a set of tasks and assessments to determine whether subjects used the heuristics in reasoning, to obtain initial frequencies of heuristic use and related cognitive errors, and to collect cognitive process data using think-aloud techniques. The study investigates two aspects of the Representativeness heuristic - judging by perceived frequency and representativeness as causal beliefs. Results show that subjects apply both aspects of the heuristic during reasoning, and make errors related to misapplication of these heuristics. Subjects in this study rarely used base rates, showed significant variability in their recall of base rates, demonstrated limited ability to use provided base rates, and favored causal data in diagnosis. We conclude that the tasks and assessments we have developed provide a suitable test-bed to study the cognitive processes underlying heuristic errors. PMID:18999140

  19. Knowledge environments representing molecular entities for the virtual physiological human.

    Science.gov (United States)

    Hofmann-Apitius, Martin; Fluck, Juliane; Furlong, Laura; Fornes, Oriol; Kolárik, Corinna; Hanser, Susanne; Boeker, Martin; Schulz, Stefan; Sanz, Ferran; Klinger, Roman; Mevissen, Theo; Gattermayer, Tobias; Oliva, Baldo; Friedrich, Christoph M

    2008-09-13

    In essence, the virtual physiological human (VPH) is a multiscale representation of human physiology spanning from the molecular level via cellular processes and multicellular organization of tissues to complex organ function. The different scales of the VPH deal with different entities, relationships and processes, and in consequence the models used to describe and simulate biological functions vary significantly. Here, we describe methods and strategies to generate knowledge environments representing molecular entities that can be used for modelling the molecular scale of the VPH. Our strategy to generate knowledge environments representing molecular entities is based on the combination of information extraction from scientific text and the integration of information from biomolecular databases. We introduce @neuLink, a first prototype of an automatically generated, disease-specific knowledge environment combining biomolecular, chemical, genetic and medical information. Finally, we provide a perspective for the future implementation and use of knowledge environments representing molecular entities for the VPH.

  20. USAID Anticorruption Projects Database

    Data.gov (United States)

    US Agency for International Development — The Anticorruption Projects Database (Database) includes information about USAID projects with anticorruption interventions implemented worldwide between 2007 and...

  1. Project 2010 Bible

    CERN Document Server

    Marmel, Elaine

    2010-01-01

    A comprehensive reference on the latest version of the leading enterprise project management software: Microsoft Project 2010. Microsoft Project allows users to manage business activities effectively by sharing project information, performing modeling and scenario analyses, standardizizing reporting processes, and more. This soup-to-nuts reference covers both the professional and standard versions of the latest iteration of Microsoft Project, as well as Project Server, so that you can efficiently manage your business projects. Veteran author Elaine Marmel begins with an overview of project man

  2. Project 2010 For Dummies

    CERN Document Server

    Muir, Nancy C

    2010-01-01

    A friendly reference guide to Microsoft Project, the leading enterprise project management software. As project management software, Microsoft Project allows you to oversee your business activities effectively. You can manage resources, share project info, perform modeling and scenario analysis, and standardize reporting processes. This easy-to-understand guide is completely updated to cover the latest changes and newest enhancements to Project 2010 and shows you how to get Project 2010 to work for you. After an introduction to basic project management concepts, you'll discover the mechanics o

  3. The Yangtze-Project

    Science.gov (United States)

    Subklew, Günter; Ulrich, Julia; Fürst, Leander; Höltkemeier, Agnes

    2010-05-01

    As an important element in Chinese politics for the development of the Western parts of the country, a large hydraulic engineering project - the Three Gorges Dam - has been set up in order to dam the Yangtze River for a length of over 600 km with an average width of about 1,100 m. It is expected that this results in ecological, technical and social problems of a magnitude hardly dealt with before. With this gigantic project, the national executive is pursuing the aims of - preventing flooding - safeguarding the water supply - encouraging navigation and - generating electric energy. In future, fluctuations of the water level of up to 30 metres will be deliberately applied in the dammed-up section of the river while retaining the flow character of the seasonal variation. The pollution of the Yangtze with a wide range of problem substances is frequently underestimated since in many cases attention is only paid to the low measured concentrations. However, the large volumes of water lead to appreciable loads and thus the danger of an accumulation of pollutants even reaching the human food chain. It should also not be forgotten that the Yangtze represents the major, and in some cases indeed the only, source of drinking and domestic water for the population. A consideration of the water level in the impoundment that will in future arise from management of the reservoir reveals the dramatic change in contrast to the natural inundation regime. In the past, the flood events on the banks of the Yangtze and its tributaries occurred in the summer months. The plants in the riparian zone (water fluctuation zone = WFZ) were previously inundated during the warmer time of year (28 ° July/August) and the terrestrial phase of the WFZ was characterized by cool temperatures (3-5 °C January) that permitted little plant activity. In future, the highest water levels will occur in winter above the dam on the Yangtze and also on the tributaries flowing into it. The plants in the WFZ will

  4. Enterprise Systems Implementations: Organizational Influence Processes for Corporate User Representatives

    DEFF Research Database (Denmark)

    Nielsen, Peter Axel; Nordheim, Stig

    2008-01-01

    -depth, interpretive study from the oil industry, where we analyze a case of innovative integration of an ECM system with collaboration technologies. The data collection has been longitudinal. The data analysis has been performed through the perspective of organizational influence processes. The main finding concerns...... an organizational role as corporate user representative to deal with the scale and complexities of implementation. A single person was particularly influential in the role. At the outset a user representative had to perform upward influence processes from a lower formal position. This is impeding...

  5. Representing and reasoning about program in situation calculus

    Science.gov (United States)

    Yang, Bo; Zhang, Ming-yi; Wu, Mao-nian; Xie, Gang

    2011-12-01

    Situation calculus is an expressive tool for modeling dynamical system in artificial intelligence, changes in a dynamical world is represented naturally by the notions of action, situation and fluent in situation calculus. Program can be viewed as a discrete dynamical system, so it is possible to model program with situation calculus. To model program written in a smaller core programming language CL, notion of fluent is expanded for representing value of expression. Together with some functions returning concerned objects from expressions, a basic action theory of CL programming is constructed. Under such a theory, some properties of program, such as correctness and termination can be reasoned about.

  6. A geometric language for representing structure in polyphonic music

    DEFF Research Database (Denmark)

    Meredith, David

    2012-01-01

    In 1981, Deutsch and Feroe proposed a formal language for representing melodic pitch structure that employed the powerful concept of hierarchically-related pitch alphabets. However, neither rhythmic structure nor pitch structure in polyphonic music can be adequately represented using this language....... A new language is proposed here that incorporates certain features of Deutsch and Feroe’s model but extends and generalises it to allow for the representation of both rhythm and pitch structure in polyphonic music. The new language adopts a geometric approach in which a passage of polyphonic music...

  7. The LHC Computing Grid Project

    CERN Multimedia

    Åkesson, T

    In the last ATLAS eNews I reported on the preparations for the LHC Computing Grid Project (LCGP). Significant LCGP resources were mobilized during the summer, and there have been numerous iterations on the formal paper to put forward to the CERN Council to establish the LCGP. ATLAS, and also the other LHC-experiments, has been very active in this process to maximally influence the outcome. Our main priorities were to ensure that the global aspects are properly taken into account, that the CERN non-member states are also included in the structure, that the experiments are properly involved in the LCGP execution and that the LCGP takes operative responsibility during the data challenges. A Project Launch Board (PLB) was active from the end of July until the 10th of September. It was chaired by Hans Hoffmann and had the IT division leader as secretary. Each experiment had a representative (me for ATLAS), and the large CERN member states were each represented while the smaller were represented as clusters ac...

  8. The Challenges and Enhancing Opportunities of Global Project Management: Evidence from Chinese and Dutch Cross-Cultural Project Management

    OpenAIRE

    Zhang, Ying; Marquis, Christopher G; Filippov, Sergey; Haasnoot, Henk-Jan; van der Steen, Martijn

    2015-01-01

    This study investigates the role of national and organisational culture in day-to-day activities of multinational project teams, specifically focusing on differences between Chinese and Dutch project managers. We rely on fieldwork observation and interviews with representatives from a diverse set of organizations in China and the Netherlands. Analyses focus on the impact of cultural differences on five project management processes – (1) project planning, (2) cost and quality management, (3) r...

  9. Project development symposium

    Energy Technology Data Exchange (ETDEWEB)

    1983-01-01

    Papers were presented on the following: project evaluation; case studies - minerals; finance; applied finance; legal; manpower/industrial relations; and new technologies. Those papers on the coal industry were: mine planning for coal project development; the planning and management of a lignite exploration contract in Thailand; development of the West Cliff extended project; Ulan: a resource development; Saxonvale mine development a case study in project planning and project management; the role of marketing in the development of a new coal project; technical support for coal marketing; infrastructure development for the Ulan project; underground mine project developments; the bucketwheel excavator at Goonyella - a case study; tax aspects of mining development projects; cost of capital mining development projects; and trends in development project finance. 16 papers were abstracted separately.

  10. Coordinated research projects (CRP). Coordinated research project (CRP)

    International Nuclear Information System (INIS)

    Takagi, Hidekazu; Koike, Fumihiro; Nakamura, Nobuyuki

    2013-01-01

    In the present paper, the contribution of Japanese scientists in coordinated research projects on thermonuclear fusion. Representative subjects taken in seven projects are the precise computation of theoretical data on electron-molecule collisions in the peripheral plasma, the computation of spectroscopic data of multi-charged tungsten ions, the spectroscopic measurement of multi-charged tungsten ions using an ion trap device, the development of collisional-radiative model for plasmas including hydrogen and helium, the computational and theoretical studies on the behavior of tungsten and beryllium in the plasma-wall interaction, the study on the property of dusts generated in fusion devices. These subjects are those of most important issues in ITER. (author)

  11. Size and Local Democracy: the Case of Czech Municipal Representatives

    Czech Academy of Sciences Publication Activity Database

    Ryšavý, D.; Bernard, Josef

    2013-01-01

    Roč. 39, č. 6 (2013), s. 833-852 ISSN 0300-3930 R&D Projects: GA ČR GA403/09/1779 Institutional support: RVO:68378025 Keywords : local councillors * size of municipality * incumbents Subject RIV: AO - Sociology, Demography Impact factor: 0.620, year: 2013 http://www.tandfonline.com/doi/pdf/10.1080/03003930.2012.675329

  12. 3D Approach for Representing Uncertainties of Underground Utility Data

    NARCIS (Netherlands)

    olde Scholtenhuis, Léon Luc; Zlatanova, S.; den Duijn, Xander; Lin, Ken-Yu; El-Gohary, Nora; Tang, Pingbo

    Availability of 3D underground information models is key to designing and managing urban infrastructure construction projects. Buried utilities information is often registered by using different types of location data with different uncertainties. These data variances are, however, not considered in

  13. The Pacific RANET Project

    Science.gov (United States)

    Postawko, S.; Ah Poe, A.; Morrissey, M.

    2004-12-01

    There are few places in the world more vulnerable to the effects of climate variability and change than the island nations of the tropical Pacific Ocean. The region also faces great challenges in communicating the issues related to climate to the general population. Lack of communications infrastructure, multiple languages, and knowledgeable personnel to deliver information, are all challenges for these countries. However, a recently developed international consortium is taking the first steps to addressing these challenges. The RANET (RAdio and interNET communications) project was originally developed for the countries of Africa, with initial funding from NOAA, to make weather, climate, and other environmental information more accessible to remote and resource-poor communities. The program is now expanding into Asia and the Pacific. RANET works to build telecommunication bridges between scientific-based products and remote communities that could benefit from such information.?The RANET project in the Pacific is a consortium of partners from the Pacific Island nations, the U.S., New Zealand, Australia, and others. Coordination of the project is loosely overseen by a Steering Committee, made up of representatives from the various interested partners. For regions where the appropriate technology exists (which includes the capital cities of nearly all of the island states of the Pacific), information is downloaded via a digital satellite receiver. This can then be broadcast within a country by many means, including Community FM Radio stations. The information distributed includes technical information needed by meteorological and related services to improve their own products and services, as well as a second level of information designed to serve communities, including weather forecasts, bulletins, warnings, etc. The primary challenge at this time is developing content that is both relevant and understandable to these remote communities. While some information will

  14. Representing User Navigation in XML Retrieval with Structural Summaries

    DEFF Research Database (Denmark)

    Ali, M. S.; Consens, Mariano P.; Larsen, Birger

    This poster presents a novel way to represent user navigation in XML retrieval using collection statistics from XML summaries. Currently, developing user navigation models in XML retrieval is costly and the models are specific to collected user assessments. We address this problem by proposing...

  15. Representing nature : Late twentieth century green infrastructures in Paris

    NARCIS (Netherlands)

    Van der Velde, J.R.T.; De Wit, S.I.

    2015-01-01

    The appreciation of green infrastructures as ‘nature’ by urban communities presents a critical challenge for the green infrastructure concept. While many green infrastructures focus on functional considerations, their refinement as places where concepts of nature are represented and where nature can

  16. On the representativeness of behavior observation samples in classrooms.

    Science.gov (United States)

    Tiger, Jeffrey H; Miller, Sarah J; Mevers, Joanna Lomas; Mintz, Joslyn Cynkus; Scheithauer, Mindy C; Alvarez, Jessica

    2013-01-01

    School consultants who rely on direct observation typically conduct observational samples (e.g., 1 30-min observation per day) with the hopes that the sample is representative of performance during the remainder of the day, but the representativeness of these samples is unclear. In the current study, we recorded the problem behavior of 3 referred students for 4 consecutive school days between 9:30 a.m. and 2:30 p.m. using duration recording in consecutive 10-min sessions. We then culled 10-min, 20-min, 30-min, and 60-min observations from the complete record and compared these observations to the true daily mean to assess their accuracy (i.e., how well individual observations represented the daily occurrence of target behaviors). The results indicated that when behavior occurred with low variability, the majority of brief observations were representative of the overall levels; however, when behavior occurred with greater variability, even 60-min observations did not accurately capture the true levels of behavior. © Society for the Experimental Analysis of Behavior.

  17. Representativeness of the European social partner organisations: Hospitals - Netherlands

    NARCIS (Netherlands)

    Grünell, M.

    2009-01-01

    The aim of this representativeness study is to identify the respective national and supranational actors (i.e. trade unions and employer organisations) in the field of industrial relations. This study will, in particular, focus on their representational quality as well as on their role in collective

  18. Representativeness of the European social partner organisations: Catering sector - Netherlands

    NARCIS (Netherlands)

    Grünell, M.

    2010-01-01

    The aim of this representativeness study is to identify the respective national and supranational actors (i.e. trade unions and employer organisations) in the field of industrial relations in the contract catering sector in the Netherlands. In order to determine their relative importance in the

  19. 'To Think Representatively': Arendt on Judgment and the Imagination

    African Journals Online (AJOL)

    ... the standpoint of the spectator, I go on to examine their most distinctive features, in particular, the link between judgment, the imagination, and the ability to think 'representatively'. I also examine the philosophical sources of Arendt's theory of judgment, namely, Kant's theory of aesthetic judgment and its criteria of validity.

  20. Cephalopods represented by beaks in the stomach of a sperm ...

    African Journals Online (AJOL)

    More than 3 000 cephalopod beaks taken from the stomach of a sperm whale stranded at Paekakariki, North Island, New Zealand, were identified to species and measured; estimates were made of the masses and standard lengths of the cephalopods represented. In all, 24 species of cephalopod in 13 families were ...

  1. 26 CFR 31.3211-3 - Employee representative supplemental tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Employee representative supplemental tax. 31... (CONTINUED) EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE Railroad Retirement Tax Act (Chapter 22, Internal Revenue Code of 1954) Tax on Employee...

  2. Understanding and Representing Changing Work Structures and Practices through Art

    Science.gov (United States)

    Wieland, Stacey M. B.

    2018-01-01

    Courses: Organizational Communication, Advanced Organizational Communication, Organizing Work, Management/Organizational History. Objectives: This activity will help students to understand major shifts in the organization of work and creatively represent changing work structures and practices. An optional follow-up assignment is included. A…

  3. Party member recruitment and the representativeness of party membership

    DEFF Research Database (Denmark)

    Kosiara-Pedersen, Karina

    Party membership figures are in decline. However, parties are still recruiting party members. Are there any differences in the social and political characteristics of old and new party members? If there is a difference, are new party members more or less representative for party voters than old...

  4. Re-Presenting Self: Reading Some Van Kalker Studio Photographs ...

    African Journals Online (AJOL)

    The photographic implement, from the earliest days of its invention in Europe, in 1839, has been used to document events considered as real. However, notions of 'reality' could be ambiguous as objects or sceneries intended to be photographed are sometimes constructed to represent an imagined stereotypical reality.

  5. A Balanced and Representative Corpus: The Effects of Strict Corpus ...

    African Journals Online (AJOL)

    Theoretically the Northern Sotho language is made up of almost 30 dialects while practically it is not so, because the standard language was formed from very few of its dialects. As a result, even today the language has no corpus which is balanced or representative owing to the fact that almost all of the available corpora ...

  6. Quantitative radiomic profiling of glioblastoma represents transcriptomic expression.

    Science.gov (United States)

    Kong, Doo-Sik; Kim, Junhyung; Ryu, Gyuha; You, Hye-Jin; Sung, Joon Kyung; Han, Yong Hee; Shin, Hye-Mi; Lee, In-Hee; Kim, Sung-Tae; Park, Chul-Kee; Choi, Seung Hong; Choi, Jeong Won; Seol, Ho Jun; Lee, Jung-Il; Nam, Do-Hyun

    2018-01-19

    Quantitative imaging biomarkers have increasingly emerged in the field of research utilizing available imaging modalities. We aimed to identify good surrogate radiomic features that can represent genetic changes of tumors, thereby establishing noninvasive means for predicting treatment outcome. From May 2012 to June 2014, we retrospectively identified 65 patients with treatment-naïve glioblastoma with available clinical information from the Samsung Medical Center data registry. Preoperative MR imaging data were obtained for all 65 patients with primary glioblastoma. A total of 82 imaging features including first-order statistics, volume, and size features, were semi-automatically extracted from structural and physiologic images such as apparent diffusion coefficient and perfusion images. Using commercially available software, NordicICE, we performed quantitative imaging analysis and collected the dataset composed of radiophenotypic parameters. Unsupervised clustering methods revealed that the radiophenotypic dataset was composed of three clusters. Each cluster represented a distinct molecular classification of glioblastoma; classical type, proneural and neural types, and mesenchymal type. These clusters also reflected differential clinical outcomes. We found that extracted imaging signatures does not represent copy number variation and somatic mutation. Quantitative radiomic features provide a potential evidence to predict molecular phenotype and treatment outcome. Radiomic profiles represents transcriptomic phenotypes more well.

  7. Crime’s face: Imagining and representing kleptomania

    NARCIS (Netherlands)

    de Haan, W.J.M.

    2015-01-01

    Marlene Dumas is regarded as one of the most important international painters of this time. In this article, an analysis is made of what her painting The Kleptomaniac (2005) and, in particular, what its title represents. Drawing upon art history, I begin by looking at the original Portrait of a

  8. The occipital place area represents the local elements of scenes.

    Science.gov (United States)

    Kamps, Frederik S; Julian, Joshua B; Kubilius, Jonas; Kanwisher, Nancy; Dilks, Daniel D

    2016-05-15

    Neuroimaging studies have identified three scene-selective regions in human cortex: parahippocampal place area (PPA), retrosplenial complex (RSC), and occipital place area (OPA). However, precisely what scene information each region represents is not clear, especially for the least studied, more posterior OPA. Here we hypothesized that OPA represents local elements of scenes within two independent, yet complementary scene descriptors: spatial boundary (i.e., the layout of external surfaces) and scene content (e.g., internal objects). If OPA processes the local elements of spatial boundary information, then it should respond to these local elements (e.g., walls) themselves, regardless of their spatial arrangement. Indeed, we found that OPA, but not PPA or RSC, responded similarly to images of intact rooms and these same rooms in which the surfaces were fractured and rearranged, disrupting the spatial boundary. Next, if OPA represents the local elements of scene content information, then it should respond more when more such local elements (e.g., furniture) are present. Indeed, we found that OPA, but not PPA or RSC, responded more to multiple than single pieces of furniture. Taken together, these findings reveal that OPA analyzes local scene elements - both in spatial boundary and scene content representation - while PPA and RSC represent global scene properties. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. 78 FR 19400 - Registry for Attorneys and Representatives

    Science.gov (United States)

    2013-04-01

    ... digits of his or her Social Security number. See 68 FR 75162. EOIR notes that online security standards... are only accredited to appear before the Department of Homeland Security. See id. \\3\\ As part of the... accredited representative registers, he or she will create a unique UserID and password for online access to...

  10. Professional Human Service Occupation Biases Represented in General Psychology Textbooks

    Science.gov (United States)

    Firmin, Michael W.; Johnson, Erica J.; Wikler, Jeremiah

    2009-01-01

    We examined the coverage given by General Psychology textbooks, representing 8 major commercial publishers, regarding the professions of psychology, counseling, marriage & family therapy, and social workers. Of the 24 textbooks assessed, we found substantial bias favoring the coverage of psychology. While 25% of the texts mentioned social workers,…

  11. Under-Representation in Nationally Representative Secondary Data

    Science.gov (United States)

    Frederick, Karen; Barnard-Brak, Lucy; Sulak, Tracey

    2012-01-01

    There has been a significant increase in the use of secondary data sets. Many such data sets purport to be nationally representative. Secondary data sets include research commissioned by the National Center for Education Statistics, the Centers for Disease Control, and other public entities. Research increasingly utilizes these secondary data in…

  12. Education and support for representative, direct and stealth democracy

    NARCIS (Netherlands)

    Coffé, Hilde; Michels, Ank

    2014-01-01

    Using data collected within the scope of a Dutch internet panel survey (LISS) in 2011, this study tracks public support for direct, stealth and representative democracy according to educational level. Our findings indicate that, in terms of overall support for each specific type of democracy, lower

  13. Communication received from the Resident Representatives of Argentina and Brazil

    International Nuclear Information System (INIS)

    1993-01-01

    The document reproduces the communication received by the Director General from the Resident Representatives of Argentina and Brazil to the Agency to inform him about the official inauguration on 9 December 1992 of the headquarters of the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC) in Rio de Janeiro

  14. 32 CFR 705.14 - Embarkation of media representatives.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Embarkation of media representatives. 705.14 Section 705.14 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES... to avoid any interpretation of such review as “censorship” or interference with freedom of the press...

  15. 40 CFR 73.33 - Authorized account representative.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Authorized account representative. 73.33 Section 73.33 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Allowance Tracking System § 73.33 Authorized account...

  16. Depression and Suicidality among Bisexual Youth: A Nationally Representative Sample

    Science.gov (United States)

    Taliaferro, Lindsay A.; Gloppen, Kari M.; Muehlenkamp, Jennifer J.; Eisenberg, Marla E.

    2018-01-01

    To address gaps in the literature on bisexual youth, we used the first nationally representative sample of high school students from the United States to determine profiles of behaviors related to depressive symptoms, a suicide attempt, and a medically-serious attempt. We examined the data from 922 bisexual students in grades 9-12 who completed…

  17. Identifying and representing elements of local contexts in Namibia

    DEFF Research Database (Denmark)

    Rodil, Kasper; Jensen, Kasper Løvborg; Rehm, Matthias

    2013-01-01

    In an attempt to represent local context in a 3D visualisa- tionfor rural elders in Namibia we have foundmajor dierences in thecon- ceptualizationof this context between external and local partners in the co-creation process. Through the evaluation of a mobile context capture tool we found a clea...

  18. Markov LIMID processes for representing and solving renewal problems

    DEFF Research Database (Denmark)

    Jørgensen, Erik; Kristensen, Anders Ringgaard; Nilsson, Dennis

    2014-01-01

    to model a Markov Limid Process, where each TemLimid represents a macro action. Algorithms are presented to find optimal plans for a sequence of such macro actions. Use of algorithms is illustrated based on an extended version of an example from pig production originally used to introduce the Limid concept...

  19. Can Democracy Represent Children? Toward a Politics of Difference

    Science.gov (United States)

    Wall, John

    2012-01-01

    Children and youth under 18 have made significant strides in recent years toward fuller inclusion in democratic processes. These strides, however, rarely rise to the level of direct political representation, whether in changing policies, making laws, or voting. This article argues that democracies will be able to represent children only by…

  20. The role of a representative reinsurer in optimal reinsurance

    NARCIS (Netherlands)

    Boonen, T.J.; Tan, K.S.; Zhuang, S.C.

    2016-01-01

    In this paper, we consider a one-period optimal reinsurance design model with nn reinsurers and an insurer. For very general preferences of the insurer and that all reinsurers use a distortion premium principle, we establish the existence of a representative reinsurer and this in turn facilitates

  1. Fiscal planning of private electricity production projects

    International Nuclear Information System (INIS)

    Gauthier, R.

    2002-01-01

    Various fiscal considerations frequently encountered in the context of the planning of private electricity production projects were described. Two major themes were discussed: 1) the different jurisdictional vehicles that can be used during the planning of private electricity production projects and the associated fiscal considerations, and 2) the two main fiscal incentives of the Income Tax Act (Canada) which could impact on the financing and operation costs of such a project, namely the accelerated amortization and the possibility of deducting the costs associated to renewable energies and energy savings in Canada. This was a general presentation that did not go into specific details and did not represent a legal opinion. refs

  2. An active learning representative subset selection method using net analyte signal

    Science.gov (United States)

    He, Zhonghai; Ma, Zhenhe; Luan, Jingmin; Cai, Xi

    2018-05-01

    To guarantee accurate predictions, representative samples are needed when building a calibration model for spectroscopic measurements. However, in general, it is not known whether a sample is representative prior to measuring its concentration, which is both time-consuming and expensive. In this paper, a method to determine whether a sample should be selected into a calibration set is presented. The selection is based on the difference of Euclidean norm of net analyte signal (NAS) vector between the candidate and existing samples. First, the concentrations and spectra of a group of samples are used to compute the projection matrix, NAS vector, and scalar values. Next, the NAS vectors of candidate samples are computed by multiplying projection matrix with spectra of samples. Scalar value of NAS is obtained by norm computation. The distance between the candidate set and the selected set is computed, and samples with the largest distance are added to selected set sequentially. Last, the concentration of the analyte is measured such that the sample can be used as a calibration sample. Using a validation test, it is shown that the presented method is more efficient than random selection. As a result, the amount of time and money spent on reference measurements is greatly reduced.

  3. PROJECT SCOPE MANAGEMENT PROCESS

    Directory of Open Access Journals (Sweden)

    Yana Derenskaya

    2018-01-01

    Full Text Available The purpose of the article is to define the essence of project scope management process, its components, as well as to develop an algorithm of project scope management in terms of pharmaceutical production. Methodology. To carry out the study, available information sources on standards of project management in whole and elements of project scope management in particular are analysed. Methods of system and structural analysis, logical generalization are used to study the totality of subprocesses of project scope management, input and output documents, and to provide each of them. Methods of network planning are used to construct a precedence diagram of project scope management process. Results of the research showed that components of the project scope management are managing the scope of the project product and managing the content of project work. It is the second component is investigated in the presented work as a subject of research. Accordingly, it is defined that project scope management process is to substantiate and bring to the realization the necessary amount of work that ensures the successful implementation of the project (achievement of its goal and objectives of individual project participants. It is also determined that the process of managing the project scope takes into account the planning, definition of the project scope, creation of the structure of project work, confirmation of the scope and management of the project scope. Participants of these subprocesses are: customer, investor, and other project participants – external organizations (contractors of the project; project review committee; project manager and project team. It is revealed that the key element of planning the project scope is the formation of the structure of design work, the justification of the number of works, and the sequence of their implementation. It is recommended to use the following sequence of stages for creating the structure of project work

  4. Introduction to the Project

    DEFF Research Database (Denmark)

    Kuhn, Johan M.; Malchow-Møller, Nikolaj; Sørensen, Anders

    In this note a short introduction to the project “Employment Effects of Entrepreneurs” is presented. First, we describe the purpose of the project; second, we present the background; third, we briefly describe the three papers that constitute the output of the project, and fourth, we discuss two...... important qualifications for the understanding of the contributions and results established in the project....

  5. The virtual GULLIVER project

    NARCIS (Netherlands)

    Trappl, R.; Nijholt, Antinus; Stuk, M.; Zwiers, Jakob

    2002-01-01

    In this paper we discuss our virtual reality project Gulliver. This project is part of a more comprehensive project conceived by two artists, Matjaž Štuk and Alena Hudcovicová, called “Gulliver’s Museum of Living Art��?. Our part of the project involves a virtual reality version of Swift’s Gulliver

  6. Innovations in project activities

    Directory of Open Access Journals (Sweden)

    Serbskaya O.V.

    2016-11-01

    Full Text Available this article considers the ways of project management, models of project management: classical model and the model of flexible designing Agile, pays more attention to the process of project management using Agile model and to the problems of using the project management models in modern conditions.

  7. The 100 People Project

    Science.gov (United States)

    McLeod, Keri

    2007-01-01

    This article describes the 100 People Project and how the author integrates the project in her class. The 100 People Project is a nonprofit organization based in New York City. The organization poses the question: If there were only 100 people in the world, what would the world look like? Through the project, students were taught about ethics in…

  8. Earth System Science Project

    Science.gov (United States)

    Rutherford, Sandra; Coffman, Margaret

    2004-01-01

    For several decades, science teachers have used bottles for classroom projects designed to teach students about biology. Bottle projects do not have to just focus on biology, however. These projects can also be used to engage students in Earth science topics. This article describes the Earth System Science Project, which was adapted and developed…

  9. Basic research projects

    International Nuclear Information System (INIS)

    1979-04-01

    The research programs under the cognizance of the Office of Energy Research (OER) are directed toward discovery of natural laws and new knowledge, and to improved understanding of the physical and biological sciences as related to the development, use, and control of energy. The ultimate goal is to develop a scientific underlay for the overall DOE effort and the fundamental principles of natural phenomena so that these phenomena may be understood, and new principles, formulated. The DOE-OER outlay activities include three major programs: High Energy Physics, Nuclear Physics, and Basic Energy Sciences. Taken together, these programs represent some 30 percent of the Nation's Federal support of basic research in the energy sciences. The research activities of OER involve more than 6,000 scientists and engineers working in some 17 major Federal Research Centers and at more than 135 different universities and industrial firms throughout the United States. Contract holders in the areas of high-energy physics, nuclear physics, materials sciences, nuclear science, chemical sciences, engineering, mathematics geosciences, advanced energy projects, and biological energy research are listed. Funding trends for recent years are outlined

  10. Coleman Collieries reclamation project

    International Nuclear Information System (INIS)

    Brand, D.

    2006-01-01

    The Municipality of Crowsnest Pass in Southern Alberta is the home to one of the largest and most important coal centres in Canada since the early 1900s. The Coleman Collieries operated from 1903 until 1983 and has been idle since 1983 with remnants of several eras of coal production being represented in the buildings remaining on the 300 acre plant site. This paper examined the remediation of the site. It included a discussion of challenges and issues such as construction and operation predating environmental legislation; its historical importance as recognized by provincial and federal governments; its location which is adjacent to a municipal business centre; and the fact that one of Alberta's most important sport fishing rivers flows through the site. The paper also discussed the need for remediation criteria and consensus with regulators, public, stakeholders, and municipal, provincial and federal governments as to a final land use plan for the property. The paper discussed progress and status of the project and provided an update on stakeholder consultation as well as future work. A subgroup of the Coleman Collieries Liaison Committee is working on an historical development proposal for the remainder of the site with the purpose of developing a financially sustainable historical site that is acceptable to the local community. Other options being considered include parkland, commercial and residential development

  11. Projects as value constellations

    DEFF Research Database (Denmark)

    Laursen, Markus

    Creating value has been outlined as very central to projects applying the organizational perspective to projects. It has been suggested that value is created in value constellations or project networks, where actors work together to create value. However, research on the value creation process...... in value constellations is scarce, and through an exploratory study of two project networks in a cultural setting we investigate how value is created in value constellations. We outline how each project may be a distinct type of value constellation, one project creates value for the partners of the network...... as a consortium, and the project creates value primarily for others as a facilitator....

  12. Project stakeholder management

    CERN Document Server

    Eskerod, Pernille

    2013-01-01

    Carrying out a project as planned is not a guarantee for success. Projects may fail because project management does not take the requirements, wishes and concerns of stakeholders sufficiently into account. Projects can only be successful though contributions from stakeholders. And in the end, it is the stakeholders that evaluate whether they find that the project is a success. To manage stakeholders effectively, you need to know your stakeholders, their behaviours and attitudes towards the project. In Project Stakeholder Management, the authors give guidance on how to adopt an analytical and s

  13. Modern project-management

    CERN Multimedia

    CERN. Geneva

    2003-01-01

    This lecture will focus on the following issues: - The current state of the art in Project Management, especially the integration of Project Management with general management activities, and the integrated view of resources allocation. - Overview of the project life cycle, the phases and the deliverables - Necessity and limits of planning in a research environment - Organizational aspects of the projects the roles of the stakeholders - How to get the resources when they are needed - Risk Management in Projects - Earned value - How to keep a project on track (schedule and budget) - Management of the suppliers - Closing of the project

  14. Introduction to the Project

    DEFF Research Database (Denmark)

    Kuhn, Johan M.; Malchow-Møller, Nikolaj; Sørensen, Anders

    In this note a short introduction to the project “Employment Effects of Entrepreneurs” is presented. First, we describe the purpose of the project; second, we present the background; third, we briefly describe the three papers that constitute the output of the project, and fourth, we discuss two ...... important qualifications for the understanding of the contributions and results established in the project.......In this note a short introduction to the project “Employment Effects of Entrepreneurs” is presented. First, we describe the purpose of the project; second, we present the background; third, we briefly describe the three papers that constitute the output of the project, and fourth, we discuss two...

  15. Choice of large projects

    Energy Technology Data Exchange (ETDEWEB)

    Harris, R

    1978-08-01

    Conventional cost/benefit or project analysis has generally not taken into account circumstances in which the project under consideration is large enough that its introduction to the economy would have significant general equilibrium effects. In this paper, rules are examined that would indicate whether such large projects should be accepted or rejected. The rules utilize information yielded by before-project and after-project equilibrium prices and production data. Rules are developed for the undistorted ''first-best'' case, the case in which the fixed costs of the project are covered by distortionary taxation, and for the case of projects producing public goods. 34 references.

  16. Project Half Double

    DEFF Research Database (Denmark)

    Svejvig, Per; Gerstrøm, Anna; Frederiksen, Signe Hedeboe

    The Half Double mission: Project Half Double has a clear mission. We want to succeed in finding a project methodology that can increase the success rate of our projects while increasing the development speed of new products and services. We are convinced that by doing so we can strengthen...... the competitiveness of Denmark and play an important role in the battle for jobs and future welfare. The overall goal is to deliver “Projects in half the time with double the impact” where projects in half the time should be understood as half the time to impact (benefit realization, effect is achieved......) and not as half the time for project execution. The Half Double project journey: It all began in May 2013 when we asked ourselves: How do we create a new and radical project paradigm that can create successful projects? Today we are a movement of hundreds of passionate project people, and it grows larger...

  17. Ongoing Projects on Serious Games

    Directory of Open Access Journals (Sweden)

    Carlos Vaz de Carvalho

    2014-08-01

    Full Text Available This number of the EAI Transactions on Serious Games is dedicated to a set of ongoing research and development projects in this area. The selected articles represent very well the diversity of approaches, contexts and objectives that foster and render highly dynamic this area of study. In Europe, several funding programmes like the 7th Framework Programme, the Lifelong Learning Programme and the most recent Horizon 2020 made specific provisions to support Serious Games projects. At the same time, enterprises are recognizing more and more the potential of SG to train and to motivate their workforce and are therefore joining forces with the academy and SG producers to design specific SG. Serious Games became one of the most interesting “places to be” due to its growing scientific and practitioner community. We can say that the motivating and addictive character of games has been successfully transmitted to the research and development of Serious Games.

  18. Temporary Residences: a becoming project

    Directory of Open Access Journals (Sweden)

    Luisa Ingaramo

    2012-04-01

    Full Text Available Among the experimental actions fostered so far by the Compagnia di San Paolo through its Housing Program, committed in handling the complex and fragmented housing discomfort issue, the Temporary Dwellings initiative represents a unique and innovative experience, as it actually offers the chance to activate a proper managerial direction around and about the real estate development processes. In particular, the Temporary Dwellings action is marked by two key aspects: a structured co-planning vision and projects selected through a requests for proposal system. The process in the whole aims on the one hand at reaching an high transparent level of decision making , while, on the other hand, at developing a continuous and mutual monitoring and matching activity between the Housing Program and the group of cross-curricular experts teamed up in the project: technicians, designers, managers, psychologists, contractors, and the other local stakeholders.

  19. Project Finance: Basic Components

    OpenAIRE

    Alfieri Li Ojeda, Jaime

    2015-01-01

    The natural speed of the contemporary world demands large investment projects which require specialized financial techniques such as Project Finance, defined as a fund to finance investment projects of great magnitude. Every Project Finance involves a wide range of elements such as promoters, government, contractors andsuppliers, among others, that will ensure project success. La rapidez del mundo contemporáneo exige que los grandes proyectos de inversión requieran de técnicas financieras ...

  20. Project delivery system (PDS)

    CERN Document Server

    2001-01-01

    As business environments become increasingly competitive, companies seek more comprehensive solutions to the delivery of their projects. "Project Delivery System: Fourth Edition" describes the process-driven project delivery systems which incorporates the best practices from Total Quality and is aligned with the Project Management Institute and ISO Quality Standards is the means by which projects are consistently and efficiently planned, executed and completed to the satisfaction of clients and customers.

  1. IT Project Management Metrics

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available Many software and IT projects fail in completing theirs objectives because different causes of which the management of the projects has a high weight. In order to have successfully projects, lessons learned have to be used, historical data to be collected and metrics and indicators have to be computed and used to compare them with past projects and avoid failure to happen. This paper presents some metrics that can be used for the IT project management.

  2. Methodologies of Project Management

    Directory of Open Access Journals (Sweden)

    Wojciech Macek

    2011-07-01

    Full Text Available This paper presents comparison of three most popular project management standardsbelonging to a wider group of models (for example, PMBOK, Prince 2, CMMI, ISO 10006,BS 6079, IPMA Competence Baseline, European Commission Project Cycle ManagementGuidelines. The author discusses methods of project management according to PMBoK,Prince 2 and ISO 10006, some chosen criteria and fields of knowledge, such as generalregulations of standards, project range management, resources management, and processesconnected with risk, systems of project quality management.

  3. Quality planning in Construction Project

    Science.gov (United States)

    Othman, I.; Shafiq, Nasir; Nuruddin, M. F.

    2017-12-01

    The purpose of this paper is to investigate deeper on the factors that contribute to the effectiveness of quality planning, identifying the common problems encountered in quality planning, practices and ways for improvements in quality planning for construction projects. This paper involves data collected from construction company representatives across Malaysia that are obtained through semi-structured interviews as well as questionnaire distributions. Results shows that design of experiments (average index: 4.61), inspection (average index: 4.45) and quality audit as well as other methods (average index: 4.26) rank first, second and third most important factors respectively.

  4. An affordable proxy of representative national survey on radon concentration in dwellings: Design, organisation and preliminary evaluation of representativeness

    International Nuclear Information System (INIS)

    Antignani, Sara; Carelli, Vinicio; Cordedda, Carlo; Zonno, Fedele; Ampollini, Marco; Carpentieri, Carmela; Venoso, Gennaro; Bochicchio, Francesco

    2013-01-01

    Representative national surveys in dwellings are important to unbiasedly evaluate the exposure of the general population to radon. In Italy, a representative national survey was conducted from 1989 to 1996, which involved about 5600 dwellings in 232 towns. Later on, some Regions carried out more detailed surveys, but a new national survey in dwellings is necessary in order to obtain a more thorough estimate of radon concentration distribution over the Italian territory. The need to make this survey in an affordable way led to implement a new approach based on the collaboration between the Istituto Superiore di Sanità and a national company with workplaces and employees' homes throughout the country. The intent is to carry out a proxy of a population representative survey by measuring radon concentration in the homes of a random sample of the company employees. The realisation of this survey was affordable, thanks to the availability of corporate e-mail for each employee, intranet service, and company internal mail service. A dedicated web procedure and e-questionnaires allowed to automatically manage the contact with employees and to collect their data, which were both cost- and time-saving. Using this e-mail contact approach, 53% of contacted employees consented to participate in the survey. Radon concentration passive measuring devices were distributed to about 7000 dwellings, using about 14000 CR-39 detectors (two measured rooms per dwelling). In order to reduce costs, the devices were exposed for 12 months instead of two consecutive 6-month periods (as with the former national survey). A first checking of the actual representativeness of the sample was done by comparing characteristics of dwellings and occupants in the sample with corresponding data from the latest National Census. This was accomplished thanks to the fact that the questions in the survey questionnaire were tailored to the categories adopted for the Census questionnaire. A preliminary

  5. Thirteenth meeting of representatives of RCA Member States

    International Nuclear Information System (INIS)

    1986-07-01

    The 13th Meeting of Member States of RCA (Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology) was held on 26 September 1984 in Vienna. This document constitutes the report of that meeting. It includes the list of participants, agenda, summary of discussions, and 1984 costing table. The Report of Recommendations for the meeting consisted of the Summary Report of the Sixth RCA Working Group Meeting held in Kalpakkam, India, 20-23 March 1984. This Summary Report dealt with such topics as RCA research projects (including nuclear techniques to improve legume and buffalo production, radiosterilization of medical supplies, maintenance of nuclear instruments, isotope applications in hydrology and sedimentology), progress of the RCA/UNDP Industrial Project, and future programmes and budget

  6. Representing cognitive activities and errors in HRA trees

    International Nuclear Information System (INIS)

    Gertman, D.I.

    1992-01-01

    A graphic representation method is presented herein for adapting an existing technology--human reliability analysis (HRA) event trees, used to support event sequence logic structures and calculations--to include a representation of the underlying cognitive activity and corresponding errors associated with human performance. The analyst is presented with three potential means of representing human activity: the NUREG/CR-1278 HRA event tree approach; the skill-, rule- and knowledge-based paradigm; and the slips, lapses, and mistakes paradigm. The above approaches for representing human activity are integrated in order to produce an enriched HRA event tree -- the cognitive event tree system (COGENT)-- which, in turn, can be used to increase the analyst's understanding of the basic behavioral mechanisms underlying human error and the representation of that error in probabilistic risk assessment. Issues pertaining to the implementation of COGENT are also discussed

  7. Chaos control applied to cardiac rhythms represented by ECG signals

    International Nuclear Information System (INIS)

    Borem Ferreira, Bianca; Amorim Savi, Marcelo; Souza de Paula, Aline

    2014-01-01

    The control of irregular or chaotic heartbeats is a key issue in cardiology. In this regard, chaos control techniques represent a good alternative since they suggest treatments different from those traditionally used. This paper deals with the application of the extended time-delayed feedback control method to stabilize pathological chaotic heart rhythms. Electrocardiogram (ECG) signals are employed to represent the cardiovascular behavior. A mathematical model is employed to generate ECG signals using three modified Van der Pol oscillators connected with time delay couplings. This model provides results that qualitatively capture the general behavior of the heart. Controlled ECG signals show the ability of the strategy either to control or to suppress the chaotic heart dynamics generating less-critical behaviors. (paper)

  8. Vulvar Skin Disorders throughout Lifetime: About Some Representative Dermatoses

    Directory of Open Access Journals (Sweden)

    Jean Doyen

    2014-01-01

    Full Text Available The objective of this paper is to present general considerations which should be kept in mind by clinicians in charge of women with vulvar diseases. Four representative vulvar dermatoses are described. Lichen simplex chronicus is a pathological condition related to chemical and mechanical irritant agents. Detrimental effects of these irritants, in the presence of other dermatoses, have to be considered when therapeutic responses are unsatisfactory. Lichen sclerosus is the most common vulvar dermatosis in elderly. However, it should be kept in mind that it may be diagnosed at any age. Lichen planus, in spite of sharing a similar range of etiological factors with lichen sclerosus, is a very distinct entity. Finally, Paget’s disease, although rare, is also described especially because of the challenge it represents both clinically and therapeutically.

  9. Representing the environment 3.0. Maps, models, networks.

    Directory of Open Access Journals (Sweden)

    Letizia Bollini

    2014-05-01

    Full Text Available Web 3.0 is changing the world we live and perceive the environment anthropomorphized, making a stratifation of levels of experience and mediated by the devices. If the urban landscape is designed, shaped and planned space, there is a social landscape that overwrite the territory of values, representations shared images, narratives of personal and collective history. Mobile technology introduces an additional parameter, a kind of non-place, which allows the coexistence of the here and elsewhere in an sort of digital landscape. The maps, mental models, the system of social networks become, then, the way to present, represented and represent themselves in a kind of ideal coring of the co-presence of levels of physical, cognitive and collective space.

  10. Antecedents and Consequences of Sales Representatives' Relationship Termination Competence

    DEFF Research Database (Denmark)

    Geersbro, Jens; Ritter, Thomas

    2013-01-01

    . In addition, termination competence significantly affects the value of customer portfolios. Practical implications: The findings suggest that managers should more actively consider relationship termination as a legitimate option in customer relationship management. In order to increase the value of a firm......'s customer portfolio, managers must not only provide a clear definition of the types of customers the organization does not want to serve, but must also implement termination routines within the organization. Managers also need to establish incentives for sales representatives to terminate relationships......Purpose: Most firms have a number of unprofitable customer relationships that drain the firms' resources. However, firms in general and sales representatives in particular hesitate to address this problem and, ultimately, to terminate business relationships. This paper therefore aims to investigate...

  11. Patient representatives' views on patient information in clinical cancer trials

    DEFF Research Database (Denmark)

    Dellson, Pia; Nilbert, Mef; Carlsson, Christina

    2016-01-01

    of future simplified and more attractive informed consent forms. CONCLUSIONS: The emotional and cognitive responses to written patient information reported by patient representatives provides a basis for revised formats in future trials and add to the body of information that support use of plain language......BACKGROUND: Patient enrolment into clinical trials is based on oral information and informed consent, which includes an information sheet and a consent certificate. The written information should be complete, but at the same time risks being so complex that it may be questioned if a fully informed...... consent is possible to provide. We explored patient representatives' views and perceptions on the written trial information used in clinical cancer trials. METHODS: Written patient information leaflets used in four clinical trials for colorectal cancer were used for the study. The trials included phase I...

  12. Representing climate change on public service television: A case study.

    Science.gov (United States)

    Debrett, Mary

    2017-05-01

    Publicly funded broadcasters with a track record in science programming would appear ideally placed to represent climate change to the lay public. Free from the constraints of vested interests and the economic imperative, public service providers are better equipped to represent the scientific, social and economic aspects of climate change than commercial media, where ownership conglomeration, corporate lobbyists and online competition have driven increasingly tabloid coverage with an emphasis on controversy. This prime-time snapshot of the Australian Broadcasting Corporation's main television channel explores how the structural/rhetorical conventions of three established public service genres - a science programme, a documentary and a live public affairs talk show - impact on the representation of anthropogenic climate change. The study findings note implications for public trust, and discuss possibilities for innovation in the interests of better public understanding of climate change.

  13. Representing Scientific Communities by Data Visualization (1/2)

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    These lectures present a research that investigates the representation of communities, and the way to foster their understanding by different audiences. Communities are complex multidimensional entities intrinsically difficult to represent synthetically. The way to represent them is likely to differ depending on the audience considered: governing entities trying to make decision for the future of the community, general public trying to understand the nature of the community and the members of the community themselves. This work considers two types of communities as example: a scientific organization and an arising domain: the EPFL institutional community composed of faculty members and researchers and, at a world wide level, the emerging community of Digital Humanities researchers. For both cases, the research is organised as a process going from graphical research to actual materialization as physical artefacts (posters, maps, etc.), possibly extended using digital devices (augmented reality applications). T...

  14. Crystallochemical particularities of complexes with lower representatives of dicarboiylic acids

    International Nuclear Information System (INIS)

    Dmitrova, G.I.; Kiosse, G.A.

    1982-01-01

    A review is given of crystallochemical particularities of nonsubstituted dicarboxylic acids, HOOC-(CHsub(2))sub(n)-COOH, complexes with lower representatives of the given series (n=0.1). Besides published data, the studies on the structures obtained by the authors are included herein. From the structure data of salts and complexes with the lower representatives of dicarboxylic acids and oxyacids (among which there are complexes of rare earths and niobium) one can distinguish the formation of two-and polynuclear chelate complexes. Configuration of molecules of oxalic and malonic (and its derivatives) acids does not depend on the type of the compounds formed. The turn of carboxylic groups with respect to the plane of central carbon atoms in oxalate- and malonate-ions depends on their structural environment. The structures of complexes with malonic acid derivatives are not studied well although they are of great theoretical and practical interest

  15. Manikin families representing obese airline passengers in the US.

    Science.gov (United States)

    Park, Hanjun; Park, Woojin; Kim, Yongkang

    2014-01-01

    Aircraft passenger spaces designed without proper anthropometric analyses can create serious problems for obese passengers, including: possible denial of boarding, excessive body pressures and contact stresses, postural fixity and related health hazards, and increased risks of emergency evacuation failure. In order to help address the obese passenger's accommodation issues, this study developed male and female manikin families that represent obese US airline passengers. Anthropometric data of obese individuals obtained from the CAESAR anthropometric database were analyzed through PCA-based factor analyses. For each gender, a 99% enclosure cuboid was constructed, and a small set of manikins was defined on the basis of each enclosure cuboid. Digital human models (articulated human figures) representing the manikins were created using a human CAD software program. The manikin families were utilized to develop design recommendations for selected aircraft seat dimensions. The manikin families presented in this study would greatly facilitate anthropometrically accommodating large airline passengers.

  16. Processes, data structures, and apparatuses for representing knowledge

    Science.gov (United States)

    Hohimer, Ryan E [West Richland, WA; Thomson, Judi R [Guelph, CA; Harvey, William J [Richland, WA; Paulson, Patrick R [Pasco, WA; Whiting, Mark A [Richland, WA; Tratz, Stephen C [Richland, WA; Chappell, Alan R [Seattle, WA; Butner, R Scott [Richland, WA

    2011-09-20

    Processes, data structures, and apparatuses to represent knowledge are disclosed. The processes can comprise labeling elements in a knowledge signature according to concepts in an ontology and populating the elements with confidence values. The data structures can comprise knowledge signatures stored on computer-readable media. The knowledge signatures comprise a matrix structure having elements labeled according to concepts in an ontology, wherein the value of the element represents a confidence that the concept is present in an information space. The apparatus can comprise a knowledge representation unit having at least one ontology stored on a computer-readable medium, at least one data-receiving device, and a processor configured to generate knowledge signatures by comparing datasets obtained by the data-receiving devices to the ontologies.

  17. Combining 3d Volume and Mesh Models for Representing Complicated Heritage Buildings

    Science.gov (United States)

    Tsai, F.; Chang, H.; Lin, Y.-W.

    2017-08-01

    This study developed a simple but effective strategy to combine 3D volume and mesh models for representing complicated heritage buildings and structures. The idea is to seamlessly integrate 3D parametric or polyhedral models and mesh-based digital surfaces to generate a hybrid 3D model that can take advantages of both modeling methods. The proposed hybrid model generation framework is separated into three phases. Firstly, after acquiring or generating 3D point clouds of the target, these 3D points are partitioned into different groups. Secondly, a parametric or polyhedral model of each group is generated based on plane and surface fitting algorithms to represent the basic structure of that region. A "bare-bones" model of the target can subsequently be constructed by connecting all 3D volume element models. In the third phase, the constructed bare-bones model is used as a mask to remove points enclosed by the bare-bones model from the original point clouds. The remaining points are then connected to form 3D surface mesh patches. The boundary points of each surface patch are identified and these boundary points are projected onto the surfaces of the bare-bones model. Finally, new meshes are created to connect the projected points and original mesh boundaries to integrate the mesh surfaces with the 3D volume model. The proposed method was applied to an open-source point cloud data set and point clouds of a local historical structure. Preliminary results indicated that the reconstructed hybrid models using the proposed method can retain both fundamental 3D volume characteristics and accurate geometric appearance with fine details. The reconstructed hybrid models can also be used to represent targets in different levels of detail according to user and system requirements in different applications.

  18. Model Complexities of Shallow Networks Representing Highly Varying Functions

    Czech Academy of Sciences Publication Activity Database

    Kůrková, Věra; Sanguineti, M.

    2016-01-01

    Roč. 171, 1 January (2016), s. 598-604 ISSN 0925-2312 R&D Projects: GA MŠk(CZ) LD13002 Grant - others:grant for Visiting Professors(IT) GNAMPA-INdAM Institutional support: RVO:67985807 Keywords : shallow networks * model complexity * highly varying functions * Chernoff bound * perceptrons * Gaussian kernel units Subject RIV: IN - Informatics, Computer Science Impact factor: 3.317, year: 2016

  19. The Ulysses Project. Integrating the Curriculum.

    Science.gov (United States)

    Smith, Susan Swenton

    2001-01-01

    Offers a project developed as an outgrowth of sixth-grade students' study of ancient Greece in history, English, drama, and art classes. Explains that the students created sculptures inspired by Greek sculpture that represented student perceptions of the activities and emotions found in the Ulysses myth. (CMK)

  20. Photovoltaic technologies and the genesis project

    International Nuclear Information System (INIS)

    Kuwano, Y.

    1994-01-01

    In this paper, the author first presents briefly global environmental problems and energy problems, as well as recent trends in representative types of solar cell. Next, he gives examples of applications for these solar cells, and finally discusses future prospects for solar cells in the form of the GENESIS project. (TEC). 12 figs., 4 refs

  1. Representing electrons a biographical approach to theoretical entities

    CERN Document Server

    Arabatzis, Theodore

    2006-01-01

    Both a history and a metahistory, Representing Electrons focuses on the development of various theoretical representations of electrons from the late 1890s to 1925 and the methodological problems associated with writing about unobservable scientific entities. Using the electron-or rather its representation-as a historical actor, Theodore Arabatzis illustrates the emergence and gradual consolidation of its representation in physics, its career throughout old quantum theory, and its appropriation and reinterpretation by chemists. As Arabatzis develops this novel biographical

  2. Obtaining Samples Representative of Contaminant Distribution in an Aquifer

    International Nuclear Information System (INIS)

    Schalla, Ronald; Spane, Frank A.; Narbutovskih, Susan M.; Conley, Scott F.; Webber, William D.

    2002-01-01

    Historically, groundwater samples collected from monitoring wells have been assumed to provide average indications of contaminant concentrations within the aquifer over the well-screen interval. In-well flow circulation, heterogeneity in the surrounding aquifer, and the sampling method utilized, however, can significantly impact the representativeness of samples as contaminant indicators of actual conditions within the surrounding aquifer. This paper identifies the need and approaches essential for providing cost-effective and technically meaningful groundwater-monitoring results. Proper design of the well screen interval is critical. An accurate understanding of ambient (non-pumping) flow conditions within the monitoring well is essential for determining the contaminant distribution within the aquifer. The ambient in-well flow velocity, flow direction and volumetric flux rate are key to this understanding. Not only do the ambient flow conditions need to be identified for preferential flow zones, but also the probable changes that will be imposed under dynamic conditions that occur during groundwater sampling. Once the in-well flow conditions are understood, effective sampling can be conducted to obtain representative samples for specific depth zones or zones of interest. The question of sample representativeness has become an important issue as waste minimization techniques such as low flow purging and sampling are implemented to combat the increasing cost of well purging and sampling at many hazardous waste sites. Several technical approaches (e.g., well tracer techniques and flowmeter surveys) can be used to determine in-well flow conditions, and these are discussed with respect to both their usefulness and limitations. Proper fluid extraction methods using minimal, (low) volume and no purge sampling methods that are used to obtain representative samples of aquifer conditions are presented

  3. DOES FAIR VALUE REPRESENT A CONCERN FOR ROMANIAN RESEARCHERS?

    Directory of Open Access Journals (Sweden)

    Jurcau Anca-Sabina

    2010-07-01

    Full Text Available In the actual economic context, the fair value concept is of high interest .We tried to see if the concept is only talk about, or if research in Romania has been actually done on this theme. We have analyzed the Romanian Journals recognized by CNCSIS in order to see if this concept represents a concern for Romanian researchers. This article is a literature review of the economic Romanian journals recognize by CNCSIS in the field of “fair value”.

  4. Patient representatives? views on patient information in clinical cancer trials

    OpenAIRE

    Dellson, Pia; Nilbert, Mef; Carlsson, Christina

    2016-01-01

    Background Patient enrolment into clinical trials is based on oral information and informed consent, which includes an information sheet and a consent certificate. The written information should be complete, but at the same time risks being so complex that it may be questioned if a fully informed consent is possible to provide. We explored patient representatives? views and perceptions on the written trial information used in clinical cancer trials. Methods Written patient information leaflet...

  5. The Parliament of Catalonia, representing a millenary people

    OpenAIRE

    Mateu Vilaseca, Marcel

    2017-01-01

    Catalonia is a millenary nation, which the current Spanish constitutional order frames as an “autonomous community”. However, Catalonia as a nation was not born with the Spanish Constitution in 1978, nor has any possibility for the future been democratically barred. The most important contribution to Catalonia made by the 1978 Constitution was to make it possible for the Catalan Statute to create the Catalan Parliament, an institution that democratically represents the people of Catalonia and...

  6. Representing value judgements in the evaluation options for nuclear waste

    International Nuclear Information System (INIS)

    Watson, S.R.

    1985-08-01

    In this report we show how the concept of Best Practical Environmental Option for nuclear waste management may be articulated using the methods of Multi-attribute Value Analysis. The concept of characteristic weights is introduced to represent differences of opinion on the relative importance of different factors that may reasonably be held, and show how these may be used to summarise information for decision-makers in a concise way. (author)

  7. Early menarche and childhood adversities in a nationally representative sample

    OpenAIRE

    Henrichs, Kimberly L; McCauley, Heather L; Miller, Elizabeth; Styne, Dennis M; Saito, Naomi; Breslau, Joshua

    2014-01-01

    Background Epidemiological evidence suggests that early menarche, defined as onset of menses at age 11 or earlier, has increased in prevalence in recent birth cohorts and is associated with multiple poor medical and mental health outcomes in adulthood. There is evidence that childhood adversities occurring prior to menarche contribute to early menarche. Methods Data collected in face-to-face interviews with a nationally representative sample of women age 18 and over (N = 3288), as part of the...

  8. Representing health and illness: thoughts for the 21st century.

    Science.gov (United States)

    Gilman, Sander L

    2011-06-01

    The on-going discussion about a new empiricism in the study of the medical humanities has lead to a misapprehension about the problems attendant to representing health and illness. The difficulty in understanding the politics of health and illness as well as the concomitant new aestheticism that has arisen concerning its representation demands a rethinking of these categories in the 21st century. Obesity can provide a model for the importance of this problem today.

  9. Representativeness of the IAGOS airborne measurements in the lower troposphere

    OpenAIRE

    Petetin, H.; Jeoffrion, M.; Sauvage, B.; Athier, G.; Blot, R.; Boulanger, D.; Clark, H.; Cousin, J.-M.; Gheusi, F.; Nedelec, P.; Steinbacher, M.; Thouret, V.

    2018-01-01

    In the framework of the In Service Aircraft for Global Observing System (IAGOS) program, airborne in-situ O3 and CO measurements are performed routinely using in-service aircraft, providing vertical profiles from the surface to about 10–12 km. Due to the specificity of IAGOS measurements (measurements around busy international airports), uncertainties exist on their representativeness in the lower troposphere as they may be impacted by emissions related to airport activities and/or other air...

  10. Risk Gambling and Personality: Results from a Representative Swedish Sample.

    Science.gov (United States)

    Sundqvist, Kristina; Wennberg, Peter

    2015-12-01

    The association between personality and gambling has been explored previously. However, few studies are based on representative populations. This study aimed at examining the association between risk gambling and personality in a representative Swedish population. A random Swedish sample (N = 19,530) was screened for risk gambling using the Lie/Bet questionnaire. The study sample (N = 257) consisted of those screening positive on Lie/Bet and completing a postal questionnaire about gambling and personality (measured with the NODS-PERC and the HP5i respectively). Risk gambling was positively correlated with Negative Affectivity (a facet of Neuroticism) and Impulsivity (an inversely related facet of Conscientiousness), but all associations were weak. When taking age and gender into account, there were no differences in personality across game preference groups, though preferred game correlated with level of risk gambling. Risk gamblers scored lower than the population norm data with respect to Negative Affectivity, but risk gambling men scored higher on Impulsivity. The association between risk gambling and personality found in previous studies was corroborated in this study using a representative sample. We conclude that risk and problem gamblers should not be treated as a homogeneous group, and prevention and treatment interventions should be adapted according to differences in personality, preferred type of game and the risk potential of the games.

  11. Active Learning by Querying Informative and Representative Examples.

    Science.gov (United States)

    Huang, Sheng-Jun; Jin, Rong; Zhou, Zhi-Hua

    2014-10-01

    Active learning reduces the labeling cost by iteratively selecting the most valuable data to query their labels. It has attracted a lot of interests given the abundance of unlabeled data and the high cost of labeling. Most active learning approaches select either informative or representative unlabeled instances to query their labels, which could significantly limit their performance. Although several active learning algorithms were proposed to combine the two query selection criteria, they are usually ad hoc in finding unlabeled instances that are both informative and representative. We address this limitation by developing a principled approach, termed QUIRE, based on the min-max view of active learning. The proposed approach provides a systematic way for measuring and combining the informativeness and representativeness of an unlabeled instance. Further, by incorporating the correlation among labels, we extend the QUIRE approach to multi-label learning by actively querying instance-label pairs. Extensive experimental results show that the proposed QUIRE approach outperforms several state-of-the-art active learning approaches in both single-label and multi-label learning.

  12. Representing Spatial Layout According to Intrinsic Frames of Reference.

    Science.gov (United States)

    Xie, Chaoxiang; Li, Shiyi; Tao, Weidong; Wei, Yiping; Sun, Hong-Jin

    2017-01-01

    Mou and McNamara have suggested that object locations are represented according to intrinsic reference frames. In three experiments, we investigated the limitations of intrinsic reference frames as a mean to represent object locations in spatial memory. Participants learned the locations of seven or eight common objects in a rectangular room and then made judgments of relative direction based on their memory of the layout. The results of all experiments showed that when all objects were positioned regularly, judgments of relative direction were faster or more accurate for novel headings that were aligned with the primary intrinsic structure than for other novel headings; however, when one irregularly positioned object was added to the layout, this advantage was eliminated. The experiments further indicated that with a single view at study, participants could represent the layout from either an egocentric orientation or a different orientation, according to experimental instructions. Together, these results suggest that environmental reference frames and intrinsic axes can influence performance for novel headings, but their role in spatial memory depends on egocentric experience, layout regularity, and instructions.

  13. Patch-based visual tracking with online representative sample selection

    Science.gov (United States)

    Ou, Weihua; Yuan, Di; Li, Donghao; Liu, Bin; Xia, Daoxun; Zeng, Wu

    2017-05-01

    Occlusion is one of the most challenging problems in visual object tracking. Recently, a lot of discriminative methods have been proposed to deal with this problem. For the discriminative methods, it is difficult to select the representative samples for the target template updating. In general, the holistic bounding boxes that contain tracked results are selected as the positive samples. However, when the objects are occluded, this simple strategy easily introduces the noises into the training data set and the target template and then leads the tracker to drift away from the target seriously. To address this problem, we propose a robust patch-based visual tracker with online representative sample selection. Different from previous works, we divide the object and the candidates into several patches uniformly and propose a score function to calculate the score of each patch independently. Then, the average score is adopted to determine the optimal candidate. Finally, we utilize the non-negative least square method to find the representative samples, which are used to update the target template. The experimental results on the object tracking benchmark 2013 and on the 13 challenging sequences show that the proposed method is robust to the occlusion and achieves promising results.

  14. Using SNOMED CT to Represent Two Interface Terminologies

    Science.gov (United States)

    Rosenbloom, S. Trent; Brown, Steven H.; Froehling, David; Bauer, Brent A.; Wahner-Roedler, Dietlind L.; Gregg, William M.; Elkin, Peter L.

    2009-01-01

    Objective Interface terminologies are designed to support interactions between humans and structured medical information. In particular, many interface terminologies have been developed for structured computer based documentation systems. Experts and policy-makers have recommended that interface terminologies be mapped to reference terminologies. The goal of the current study was to evaluate how well the reference terminology SNOMED CT could map to and represent two interface terminologies, MEDCIN and the Categorical Health Information Structured Lexicon (CHISL). Design Automated mappings between SNOMED CT and 500 terms from each of the two interface terminologies were evaluated by human reviewers, who also searched SNOMED CT to identify better mappings when this was judged to be necessary. Reviewers judged whether they believed the interface terms to be clinically appropriate, whether the terms were covered by SNOMED CT concepts and whether the terms' implied semantic structure could be represented by SNOMED CT. Measurements Outcomes included concept coverage by SNOMED CT for study terms and their implied semantics. Agreement statistics and compositionality measures were calculated. Results The SNOMED CT terminology contained concepts to represent 92.4% of MEDCIN and 95.9% of CHISL terms. Semantic structures implied by study terms were less well covered, with some complex compositional expressions requiring semantics not present in SNOMED CT. Among sampled terms, those from MEDCIN were more complex than those from CHISL, containing an average 3.8 versus 1.8 atomic concepts respectively, pterms. PMID:18952944

  15. Using SNOMED CT to represent two interface terminologies.

    Science.gov (United States)

    Rosenbloom, S Trent; Brown, Steven H; Froehling, David; Bauer, Brent A; Wahner-Roedler, Dietlind L; Gregg, William M; Elkin, Peter L

    2009-01-01

    Interface terminologies are designed to support interactions between humans and structured medical information. In particular, many interface terminologies have been developed for structured computer based documentation systems. Experts and policy-makers have recommended that interface terminologies be mapped to reference terminologies. The goal of the current study was to evaluate how well the reference terminology SNOMED CT could map to and represent two interface terminologies, MEDCIN and the Categorical Health Information Structured Lexicon (CHISL). Automated mappings between SNOMED CT and 500 terms from each of the two interface terminologies were evaluated by human reviewers, who also searched SNOMED CT to identify better mappings when this was judged to be necessary. Reviewers judged whether they believed the interface terms to be clinically appropriate, whether the terms were covered by SNOMED CT concepts and whether the terms' implied semantic structure could be represented by SNOMED CT. Outcomes included concept coverage by SNOMED CT for study terms and their implied semantics. Agreement statistics and compositionality measures were calculated. The SNOMED CT terminology contained concepts to represent 92.4% of MEDCIN and 95.9% of CHISL terms. Semantic structures implied by study terms were less well covered, with some complex compositional expressions requiring semantics not present in SNOMED CT. Among sampled terms, those from MEDCIN were more complex than those from CHISL, containing an average 3.8 versus 1.8 atomic concepts respectively, pterms.

  16. Patient representatives' views on patient information in clinical cancer trials.

    Science.gov (United States)

    Dellson, Pia; Nilbert, Mef; Carlsson, Christina

    2016-02-01

    Patient enrolment into clinical trials is based on oral information and informed consent, which includes an information sheet and a consent certificate. The written information should be complete, but at the same time risks being so complex that it may be questioned if a fully informed consent is possible to provide. We explored patient representatives' views and perceptions on the written trial information used in clinical cancer trials. Written patient information leaflets used in four clinical trials for colorectal cancer were used for the study. The trials included phase I-III trials, randomized and non-randomized trials that evaluated chemotherapy/targeted therapy in the neoadjuvant, adjuvant and palliative settings. Data were collected through focus groups and were analysed using inductive content analysis. Two major themes emerged: emotional responses and cognitive responses. Subthemes related to the former included individual preferences and perceptions of effect, while subthemes related to the latter were comprehensibility and layout. Based on these observations the patient representatives provided suggestions for improvement, which largely included development of future simplified and more attractive informed consent forms. The emotional and cognitive responses to written patient information reported by patient representatives provides a basis for revised formats in future trials and add to the body of information that support use of plain language, structured text and illustrations to improve the informed consent process and thereby patient enrolment into clinical trials.

  17. Reference materials and representative test materials: the nanotechnology case

    International Nuclear Information System (INIS)

    Roebben, G.; Rasmussen, K.; Kestens, V.; Linsinger, T. P. J.; Rauscher, H.; Emons, H.; Stamm, H.

    2013-01-01

    An increasing number of chemical, physical and biological tests are performed on manufactured nanomaterials for scientific and regulatory purposes. Existing test guidelines and measurement methods are not always directly applicable to or relevant for nanomaterials. Therefore, it is necessary to verify the use of the existing methods with nanomaterials, thereby identifying where modifications are needed, and where new methods need to be developed and validated. Efforts for verification, development and validation of methods as well as quality assurance of (routine) test results significantly benefit from the availability of suitable test and reference materials. This paper provides an overview of the existing types of reference materials and introduces a new class of test materials for which the term ‘representative test material’ is proposed. The three generic concepts of certified reference material, reference material(non-certified) and representative test material constitute a comprehensive system of benchmarks that can be used by all measurement and testing communities, regardless of their specific discipline. This paper illustrates this system with examples from the field of nanomaterials, including reference materials and representative test materials developed at the European Commission’s Joint Research Centre, in particular at the Institute for Reference Materials and Measurements (IRMM), and at the Institute for Health and Consumer Protection (IHCP).

  18. Representing metarepresentations: is there theory of mind-specific cognition?

    Science.gov (United States)

    Egeth, Marc; Kurzban, Robert

    2009-03-01

    What cognitive mechanisms underlie Theory of Mind? Some infer domain-specific Theory of Mind cognition based the pattern of children diagnosed with autism failing the False Belief test but passing the False Photograph test. However, we argue that the False Belief test entails various task demands the False Photograph task does not, including the necessity to represent a higher-order representation (a metarepresentation), thus confounding the inference of domain-specificity. Instead, a general difficulty that affects representations of metarepresentations might account for the seeming domain-specific failure. Here we find that False-Belief failing False-Photograph passing children fail the Meta Photograph test, a new photograph-domain test that requires subjects to represent a metarepresentation. We conclude that people who fail the False Belief test but pass the False Photograph test do not necessarily have a content-specific Theory of Mind deficit. Instead, the general ability to represent representations and metarepresentations might underlie Theory of Mind.

  19. Representativeness of wind measurements in moderately complex terrain

    Science.gov (United States)

    van den Bossche, Michael; De Wekker, Stephan F. J.

    2018-02-01

    We investigated the representativeness of 10-m wind measurements in a 4 km × 2 km area of modest relief by comparing observations at a central site with those at four satellite sites located in the same area. Using a combination of established and new methods to quantify and visualize representativeness, we found significant differences in wind speed and direction between the four satellite sites and the central site. The representativeness of the central site wind measurements depended strongly on surface wind speed and direction, and atmospheric stability. Through closer inspection of the observations at one of the satellite sites, we concluded that terrain-forced flows combined with thermally driven downslope winds caused large biases in wind direction and speed. We used these biases to generate a basic model, showing that terrain-related differences in wind observations can to a large extent be predicted. Such a model is a cost-effective way to enhance an area's wind field determination and to improve the outcome of pollutant dispersion and weather forecasting models.

  20. Representing Matrix Cracks Through Decomposition of the Deformation Gradient Tensor in Continuum Damage Mechanics Methods

    Science.gov (United States)

    Leone, Frank A., Jr.

    2015-01-01

    A method is presented to represent the large-deformation kinematics of intraply matrix cracks and delaminations in continuum damage mechanics (CDM) constitutive material models. The method involves the additive decomposition of the deformation gradient tensor into 'crack' and 'bulk material' components. The response of the intact bulk material is represented by a reduced deformation gradient tensor, and the opening of an embedded cohesive interface is represented by a normalized cohesive displacement-jump vector. The rotation of the embedded interface is tracked as the material deforms and as the crack opens. The distribution of the total local deformation between the bulk material and the cohesive interface components is determined by minimizing the difference between the cohesive stress and the bulk material stress projected onto the cohesive interface. The improvements to the accuracy of CDM models that incorporate the presented method over existing approaches are demonstrated for a single element subjected to simple shear deformation and for a finite element model of a unidirectional open-hole tension specimen. The material model is implemented as a VUMAT user subroutine for the Abaqus/Explicit finite element software. The presented deformation gradient decomposition method reduces the artificial load transfer across matrix cracks subjected to large shearing deformations, and avoids the spurious secondary failure modes that often occur in analyses based on conventional progressive damage models.

  1. European Wind Farm Project Costs History and Projections 2008 Study

    Energy Technology Data Exchange (ETDEWEB)

    2008-10-15

    At the request of Enova (the 'Client'), Garrad Hassan and Partners Limited ('GH') has provided technical advice on capital cost expectations for wind farm developments. In summary, the work provides a survey of the present and future 5-year prognosis for costs and conditions facing developers and suppliers in the European wind power market. The report will be used as a benchmark to support tendering for future Norwegian projects. As such, it will also provide discussion of how project characteristics can influence project cost. Data Used in the Analysis GH has obtained data on the investment costs for 35 projects developed or in development in Europe. The projects represent to the extent possible the characteristics representative of potential Norwegian projects. The data used in this analysis are from actual projects in: France, Germany, Hungary, Ireland, Italy, Northern Ireland, Portugal, Scotland, Spain and Wales. The turbine capacities represented in the data are typically 2 MW or above, except in one case where a mix of turbines sizes was used at the project. GH highlights that because of high demand for turbines, the main manufacturers have recently been offering to meet delivery schedules for new orders from late 2010. For new tenders it is likely that delivery time frames offered will now be for 2011 deliveries. As a result of the current 'Seller's Market', production capacity typically relates directly to the number of turbines sold in the year; therefore for 2007 the annual production capacity was approximately 22 GW. GH is aware that turbine suppliers across the market are working to increase their production capacity in order to ease the pressure on the market, however, there are bottlenecks through the supply chain at the sub component level. As a result, increases in production capacity will likely remain at a relatively steady state in the short term. Energy Assessment The energy assessment of a project is the area

  2. Local participation in complex technological projects as bridging between different communities in Belgium

    NARCIS (Netherlands)

    Sips, K.; Craps, M.; Dewulf, A.

    2013-01-01

    Local community participation in complex technological projects, where technological innovations and risks need to be managed, is notoriously challenging. Relations with local inhabitants easily take the form of exclusion, protest, controversy or litigation. While such projects represent

  3. Project Half Double

    DEFF Research Database (Denmark)

    Svejvig, Per; Ehlers, Michael; Adland, Karoline Thorp

    activities carried out within the framework of the projects. The formal part of Project Half Double was initiated in June 2015. We started out by developing, refining and testing the Half Double methodology on seven pilot projects in the first phase of the project, which will end June 2016. The current......Project Half Double has a clear mission to succeed in finding a project methodology that can increase the success rate of our projects while increasing the speed at which we generate new ideas and develop new products and services. Chaos and complexity should be seen as a basic condition...... and as an opportunity rather than a threat and a risk. We are convinced that by doing so, we can strengthen Denmark’s competitiveness and play an important role in the battle for jobs and future welfare. The overall goal is to deliver “projects in half the time with double the impact”, where projects in half the time...

  4. Hanford Environmental Dose Reconstruction Project monthly report

    International Nuclear Information System (INIS)

    McMakin, A.H., Cannon, S.D.; Finch, S.M.

    1992-09-01

    The objective of the Hanford Environmental Dose Reconstruction MDR) Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The TSP consists of experts in envirorunental pathways. epidemiology, surface-water transport, ground-water transport, statistics, demography, agriculture, meteorology, nuclear engineering. radiation dosimetry. and cultural anthropology. Included are appointed members representing the states of Oregon, Washington, and Idaho, a representative of Native American tribes, and an individual representing the public. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed from release to impact on humans (dose estimates): Source Terms; Environmental Transport; Environmental Monitoring Data Demography, Food Consumption, and Agriculture; and Environmental Pathways and Dose Estimates

  5. DISPLAY OF PIXEL LOSS AND REPLICATION IN REPROJECTING RASTER DATA FROM THE SINUSOIDAL PROJECTION

    Science.gov (United States)

    Recent studies show the sinusoidal projection to be a superior planar projection for representing global raster datasets. This study uses the sinusoidal projection as a basis for evaluating pixel loss and replication in eight other planar map projections. The percent of pixels ...

  6. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  7. The USE Project

    DEFF Research Database (Denmark)

    Frøkjær, E.; Hornbæk, K.; Høegh, Rune Thaarup

    2006-01-01

    This paper provides experience from activities in the USE project. The USE project is a research project that aims at bridging the gap between usability evaluation and user interface design. It is conducted from 2005 to 2008 in collaboration between researchers from Aalborg University and Copenha......This paper provides experience from activities in the USE project. The USE project is a research project that aims at bridging the gap between usability evaluation and user interface design. It is conducted from 2005 to 2008 in collaboration between researchers from Aalborg University...... and Copenhagen University, and developers and managers working in software development organizations....

  8. IT Project Selection

    DEFF Research Database (Denmark)

    Pedersen, Keld

    2016-01-01

    for initiation. Most of the research on project selection is normative, suggesting new methods, but available empirical studies indicate that many methods are seldom used in practice. This paper addresses the issue by providing increased understanding of IT project selection practice, thereby facilitating...... the development of methods that better fit current practice. The study is based on naturalistic decision-making theory and interviews with experienced project portfolio managers who, when selecting projects, primarily rely on political skills, experience and personal networks rather than on formal IT project......-selection methods, and these findings point to new areas for developing new methodological support for IT project selection....

  9. TidGen Power System Commercialization Project

    Energy Technology Data Exchange (ETDEWEB)

    Sauer, Christopher R. [President & CEO; McEntee, Jarlath [VP Engineering & CTO

    2013-12-30

    ORPC Maine, LLC, a wholly-owned subsidiary of Ocean Renewable Power Company, LLC (collectively ORPC), submits this Final Technical Report for the TidGen® Power System Commercialization Project (Project), partially funded by the U.S. Department of Energy (DE-EE0003647). The Project was built and operated in compliance with the Federal Energy Regulatory Commission (FERC) pilot project license (P-12711) and other permits and approvals needed for the Project. This report documents the methodologies, activities and results of the various phases of the Project, including design, engineering, procurement, assembly, installation, operation, licensing, environmental monitoring, retrieval, maintenance and repair. The Project represents a significant achievement for the renewable energy portfolio of the U.S. in general, and for the U.S. marine hydrokinetic (MHK) industry in particular. The stated Project goal was to advance, demonstrate and accelerate deployment and commercialization of ORPC’s tidal-current based hydrokinetic power generation system, including the energy extraction and conversion technology, associated power electronics, and interconnection equipment capable of reliably delivering electricity to the domestic power grid. ORPC achieved this goal by designing, building and operating the TidGen® Power System in 2012 and becoming the first federally licensed hydrokinetic tidal energy project to deliver electricity to a power grid under a power purchase agreement in North America. Located in Cobscook Bay between Eastport and Lubec, Maine, the TidGen® Power System was connected to the Bangor Hydro Electric utility grid at an on-shore station in North Lubec on September 13, 2012. ORPC obtained a FERC pilot project license for the Project on February 12, 2012 and the first Maine Department of Environmental Protection General Permit issued for a tidal energy project on January 31, 2012. In addition, ORPC entered into a 20-year agreement with Bangor Hydro Electric

  10. Changing the Project Execution Culture at NASA Dryden

    Science.gov (United States)

    Horn, Thomas J.

    2012-01-01

    Dryden has embarked on implementing Critical Chain Project Management (CCPM) philosophies and tools to reduce workforce stress and increase the centers work throughput. This effort has been under way for over one year and represents a fundamental state change in how various projects are planned and executed at the center. The implementation of CCPM philosophies and the required cultural changes represent the most difficult aspects of the implementation.

  11. Nepal CRS project incorporates.

    Science.gov (United States)

    1983-01-01

    The Nepal Contraceptive Retail Sales (CRS) Project, 5 years after lauching product sales in June 1978, incorporated as a private, nonprofit company under Nepalese management. The transition was finalized in August 1983. The Company will work through a cooperative agreement with USAID/Kathmandu to complement the national family planning goals as the program continues to provide comtraceptives through retail channels at subsidized prices. Company objectives include: increase contraceptive sales by at least 15% per year; make CRS cost effective and move towards self sufficiency; and explore the possibility of marketing noncontraceptive health products to improve primary health care. After only5 years the program can point to some impressive successes. The number of retial shops selling family planning products increased from 100 in 1978 to over 8000, extending CRS product availability to 66 of the country's 75 districts. Retail sales have climbed dramatically in the 5-year period, from Rs 46,817 in 1978 to Rs 271,039 in 1982. Sales in terms of couple year protection CYP) have grown to 24,451 CYP(1982), a 36% increase over 1980 CYP. Since the beginning of the CRS marketing program, total distribution of contraceptives--through both CRS and the Family Planning Maternal and Child Haelth (FP/MCH) Project--has been increasing. While the FP/MCH program remains the largest distributor,contribution of CRS Products is increasing, indicating that CRS is creating new product acceptors. CRS market share in 1982 was 43% for condoms and 16% for oral contraceptives (OCs). CRS markets 5 products which are subsidized in order to be affordable to consumers as well as attractive to sellers. The initial products launched in June 1978 were Gulaf standard dose OCs and Dhaal lubricated colored condoms. A less expensive lubricates, plain Suki-Dhaal condom was introduced in June 1980 in an attempt to reach poorer rural populations, but rural distribution costs are excessive and Suki

  12. One project's waste is another project's resource

    International Nuclear Information System (INIS)

    Short, J.

    1997-01-01

    The author describes the efforts being made toward pollution prevention within the DOE complex, as a way to reduce overall project costs, in addition to decreasing the amount of waste to be handled. Pollution prevention is a concept which is trying to be ingrained into project planning. Part of the program involves the concept that ultimately the responsibility for waste comes back to the generator. Parts of the program involve efforts to reuse materials and equipment on new projects, to recycle wastes to generate offsetting revenue, and to increase awareness, accountability and incentives so as to stimulate action on this plan. Summaries of examples are presented in tables

  13. Integrated project support environments the ASPECT project

    CERN Document Server

    Brown, Alan W

    1991-01-01

    A major part of software engineering developments involve the use of computing tools which facilitate the management, maintenance, security, and building of long-scale software engineer projects. Consequently, there have been a proliferation of CASE tools and IPSES. This book looks at IPSES in general and the ASPECT project in particular, providing design and implementation details, as well as locating ASPECT in IPSE developments.Survey of integrated project support environments for more efficient software engineering**Description of a large scale IPSE--ASPECT**Evaluation of formal methods in

  14. Model parameters for representative wetland plant functional groups

    Science.gov (United States)

    Williams, Amber S.; Kiniry, James R.; Mushet, David M.; Smith, Loren M.; McMurry, Scott T.; Attebury, Kelly; Lang, Megan; McCarty, Gregory W.; Shaffer, Jill A.; Effland, William R.; Johnson, Mari-Vaughn V.

    2017-01-01

    Wetlands provide a wide variety of ecosystem services including water quality remediation, biodiversity refugia, groundwater recharge, and floodwater storage. Realistic estimation of ecosystem service benefits associated with wetlands requires reasonable simulation of the hydrology of each site and realistic simulation of the upland and wetland plant growth cycles. Objectives of this study were to quantify leaf area index (LAI), light extinction coefficient (k), and plant nitrogen (N), phosphorus (P), and potassium (K) concentrations in natural stands of representative plant species for some major plant functional groups in the United States. Functional groups in this study were based on these parameters and plant growth types to enable process-based modeling. We collected data at four locations representing some of the main wetland regions of the United States. At each site, we collected on-the-ground measurements of fraction of light intercepted, LAI, and dry matter within the 2013–2015 growing seasons. Maximum LAI and k variables showed noticeable variations among sites and years, while overall averages and functional group averages give useful estimates for multisite simulation modeling. Variation within each species gives an indication of what can be expected in such natural ecosystems. For P and K, the concentrations from highest to lowest were spikerush (Eleocharis macrostachya), reed canary grass (Phalaris arundinacea), smartweed (Polygonum spp.), cattail (Typha spp.), and hardstem bulrush (Schoenoplectus acutus). Spikerush had the highest N concentration, followed by smartweed, bulrush, reed canary grass, and then cattail. These parameters will be useful for the actual wetland species measured and for the wetland plant functional groups they represent. These parameters and the associated process-based models offer promise as valuable tools for evaluating environmental benefits of wetlands and for evaluating impacts of various agronomic practices in

  15. Representativeness of environmental impact assessment methods regarding Life Cycle Inventories.

    Science.gov (United States)

    Esnouf, Antoine; Latrille, Éric; Steyer, Jean-Philippe; Helias, Arnaud

    2018-04-15

    Life Cycle Assessment (LCA) characterises all the exchanges between human driven activities and the environment, thus representing a powerful approach for tackling the environmental impact of a production system. However, LCA practitioners must still choose the appropriate Life Cycle Impact Assessment (LCIA) method to use and are expected to justify this choice: impacts should be relevant facing the concerns of the study and misrepresentations should be avoided. This work aids practitioners in evaluating the adequacy between the assessed environmental issues and studied production system. Based on a geometrical standpoint of LCA framework, Life Cycle Inventories (LCIs) and LCIA methods were localized in the vector space spanned by elementary flows. A proximity measurement, the Representativeness Index (RI), is proposed to explore the relationship between those datasets (LCIs and LCIA methods) through an angular distance. RIs highlight LCIA methods that measure issues for which the LCI can be particularly harmful. A high RI indicates a close proximity between a LCI and a LCIA method, and highlights a better representation of the elementary flows by the LCIA method. To illustrate the benefits of the proposed approach, representativeness of LCIA methods regarding four electricity mix production LCIs from the ecoinvent database are presented. RIs for 18 LCIA methods (accounting for a total of 232 impact categories) were calculated on these LCIs and the relevance of the methods are discussed. RIs prove to be a criterion for distinguishing the different LCIA methods and could thus be employed by practitioners for deeper interpretations of LCIA results. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Representativeness of the LifeLines Cohort Study.

    Directory of Open Access Journals (Sweden)

    Bart Klijs

    Full Text Available LifeLines is a large prospective population-based three generation cohort study in the north of the Netherlands. Different recruitment strategies were adopted: recruitment of an index population via general practitioners, subsequent inclusion of their family members, and online self-registration. Our aim was to investigate the representativeness of the adult study population at baseline and to evaluate differences in the study population according to recruitment strategy.Demographic characteristics of the LifeLines study population, recruited between 2006-2013, were compared with the total adult population in the north of the Netherlands as registered in the Dutch population register. Socioeconomic characteristics, lifestyle, chronic diseases, and general health were further compared with participants of the Permanent Survey of Living Conditions within the region (2005-2011, N = 6,093. Differences according to recruitment strategy were assessed.Compared with the population of the north of the Netherlands, LifeLines participants were more often female, middle aged, married, living in a semi-urban place and Dutch native. Adjusted for differences in demographic composition, in LifeLines a smaller proportion had a low educational attainment (5% versus 14% or had ever smoked (54% versus 66%. Differences in the prevalence of various chronic diseases and low general health scores were mostly smaller than 3%. The age profiles of the three recruitment groups differed due to age related inclusion criteria of the recruitment groups. Other differences according to recruitment strategy were small.Our results suggest that, adjusted for differences in demographic composition, the LifeLines adult study population is broadly representative for the adult population of the north of the Netherlands. The recruitment strategy had a minor effect on the level of representativeness. These findings indicate that the risk of selection bias is low and that risk estimates

  17. Solar Heliospheric and INterplanetary Environment (SHINE) Students - Student Representatives' Perspectives

    Science.gov (United States)

    Pahud, D. M.; Niembro, T.

    2014-12-01

    The SHINE workshop is an annual meeting of solar and heliospheric scientists which, in addition to aiming to improve understanding of solar disturbances and their propagation to, and effect, on the Earth (shinecon.org), is dedicated to actively supporting students. This dedication is substantiated in part through the National Science Foundation (NSF) providing funding for student attendance to the workshop, which enables student participation. Another example of SHINE's commitment to its student members is the incorporation of a Student Day prior to the workshop since 2003, entirely organized and run by two student representatives. While there are variations in format from year to year, Student Day consists of tutorials and research talks exclusively by student volunteers to an audience of only students. The day is intended to provide a low-stress environment for students to learn about the various topics addressed during the workshop, to ask questions freely, and to engage in scientific discussion with other students which hopefully is a catalyst for collaboration. As a result of positive experiences, over the past decade student attendance and participation in the workshop have increased. At the SHINE 2014 workshop, nearly a third of attendees were students. SHINE student visibility has increased over the years, with student posters being advertised at breakfast, inclusion of a student day summary by the student representatives during a plenary session, and continued support from the steering committee. Students are also promoting a broader impact of SHINE sciences via increased social media presence. From a student representative's perspective, SHINE has built and fostered a healthy student community and encourages students to engage in shaping the future of the field.

  18. Out-of-Autoclave Manufacturing of Aerospace Representative Parts

    Science.gov (United States)

    Cauberghs, Julien

    The use of carbon fibre reinforced composites for aerospace structures has seen a high increase in recent years, and is still growing. The high stiffness-to-weight ratio of these materials makes them ideal for primary structures on airplanes, satellites, and spacecrafts. Nevertheless, the manufacturing of composites remains very costly since it requires equipment investment such as an autoclave, and very qualified workers. Out-of-autoclave manufacturing technology is very promising since it only requires a traditional oven, while still aiming at similar part quality. However, the absence of positive pressure compared with an autoclave makes it more difficult to achieve low porosity parts. This research investigates the manufacturing of complex features with out-of autoclave prepreg technology. The features studied are tight-radius corners with a curvature change, and ply drop-offs. Ply drop-offs tests were conducted to identify if porosity is higher at ply terminations. In corners, the bagging arrangement was modified to achieve the most uniform thickness in areas of curvature change, even with small radii. The conclusions from these studies provided us with guidelines to manufacture larger representative parts, which included these features. The representative parts were tested for porosity, thickness uniformity, mechanical performance, and glass transition temperature (Tg). A total of four representative parts were manufactured with out-of-autoclave technology, and one more was manufactured with an autoclave to allow for a proper comparison between the two processes. The materials used were MTM45-1 5 harness satin and CYCOM5320 plain weave for the out-of-autoclave parts, and CYCOM5276-1 plain weave for the autoclave part. The effect of ply drop-offs on porosity was found to be negligible. Thickness deviation in corners was attributed to a combination of consumable bridging, prepreg's bulk factor and inter-ply shear. Overall, out-of-autoclave prepregs showed

  19. Representative Vector Machines: A Unified Framework for Classical Classifiers.

    Science.gov (United States)

    Gui, Jie; Liu, Tongliang; Tao, Dacheng; Sun, Zhenan; Tan, Tieniu

    2016-08-01

    Classifier design is a fundamental problem in pattern recognition. A variety of pattern classification methods such as the nearest neighbor (NN) classifier, support vector machine (SVM), and sparse representation-based classification (SRC) have been proposed in the literature. These typical and widely used classifiers were originally developed from different theory or application motivations and they are conventionally treated as independent and specific solutions for pattern classification. This paper proposes a novel pattern classification framework, namely, representative vector machines (or RVMs for short). The basic idea of RVMs is to assign the class label of a test example according to its nearest representative vector. The contributions of RVMs are twofold. On one hand, the proposed RVMs establish a unified framework of classical classifiers because NN, SVM, and SRC can be interpreted as the special cases of RVMs with different definitions of representative vectors. Thus, the underlying relationship among a number of classical classifiers is revealed for better understanding of pattern classification. On the other hand, novel and advanced classifiers are inspired in the framework of RVMs. For example, a robust pattern classification method called discriminant vector machine (DVM) is motivated from RVMs. Given a test example, DVM first finds its k -NNs and then performs classification based on the robust M-estimator and manifold regularization. Extensive experimental evaluations on a variety of visual recognition tasks such as face recognition (Yale and face recognition grand challenge databases), object categorization (Caltech-101 dataset), and action recognition (Action Similarity LAbeliNg) demonstrate the advantages of DVM over other classifiers.

  20. [Fundamental role of the workers' representative in preventive safety activity].

    Science.gov (United States)

    Ossicini, A; Bindi, L; Casale, M C

    2003-01-01

    With the arrival of Legislative Decree 626/94 which brought into Italian law the EU directives on workers' health and safety at the workplace, our country has also introduced rules that make a break with the past in this area, with the creation of new professional roles. The workers' safety representative takes on a fundamentally important role in the management of prevention, safety and health for workers in their place of employment in accordance with article 19. In fact, before the introduction of this Legislative Decree, the "protection" of workers' health was essentially based on rules and regulations the application of which was left to the exclusive and direct responsibility of the relationship between the employer and doctor, leaving out any participation by the worker. Whereas in the past workers could only be considered the final receivers of instructions about the security measures to apply, with Law 626 the workers themselves became active participants in the assessment of risks at work and consequently in the implementing of all the safety and hygiene measures contributing to the reduction of risk levels. The new regulations now in force assign important tasks to the workers' safety representative; all tasks and responsibilities associated with that role are examined and discussed, especially those relating to rights to information and training, consultation and participation in the process of designing and promoting safety measures. The job of workers' representative today takes on a fundamentally important meaning and role in a self-regulating system of work safety, where he or she has a proper area responsibility, so becoming a reference point for the workers generally.

  1. Evaluating the feasibility and participants' representativeness of an online nationwide surveillance system for influenza in France.

    Directory of Open Access Journals (Sweden)

    Marion Debin

    Full Text Available The increasing Internet coverage and the widespread use of digital devices offer the possibility to develop new digital surveillance systems potentially capable to provide important aid to epidemiological and public health monitoring and research. In France, a new nationwide surveillance system for influenza-like illness, GrippeNet.fr, was introduced since the 2011/2012 season based on an online participatory mechanism and open to the general population. We evaluate the recruitment and participation of users to the first pilot season with respect to similar efforts in Europe to assess the feasibility of establishing a participative network of surveillance in France. We further investigate the representativeness of the GrippeNet.fr population along a set of indicators on geographical, demographic, socio-economic and health aspects. Participation was widespread in the country and with rates comparable to other European countries with partnered projects running since a longer time. It was not representative of the general population in terms of age and gender, however all age classes were represented, including the older classes (65+ years old, generally less familiar with the digital world, but considered at high risk for influenza complications. Once adjusted on demographic indicators, the GrippeNet.fr population is found to be more frequently employed, with a higher education level and vaccination rate with respect to the general population. A similar propensity to commute for work to different regions was observed, and no significant difference was found for asthma and diabetes. Results show the feasibility of the system, provide indications to inform adjusted epidemic analyses, and highlight the presence of specific population groups that need to be addressed by targeted communication strategies to achieve a higher representativeness in the following seasons.

  2. The live album or many ways of representing performance

    Directory of Open Access Journals (Sweden)

    Mazzanti Sergio

    2014-01-01

    Full Text Available The analysis of live albums can clarify the dialectic between studio recordings and live performances. After discussing key concepts such as authenticity, space, time and place, and documentation, the author gives a preliminary definition of live albums, combining available descriptions and comparing them with different typologies and functions of these recordings. The article aims to give a new definition of the concept of live albums, gathering their primary elements: “A live album is an officially released extended recording of popular music representing one or more actually occurred public performances”.

  3. Direct and Representative Democracy - Supplementing, not Excluding Each Other

    DEFF Research Database (Denmark)

    Svensson, Palle

    2007-01-01

    : and (4) more transparency and enlightened understanding versus less confidentiality. The arguments are discussed in relation to general political goals of good government such as legitimacy, efficiency and stability. The basic thesis of the paper is that direct and representative forms of democracy...... are not exclusive. Much of the disagreement among those in favour of and in opposition to the introduction of more elements of direct democracy is caused by arguments that could be tested empirically and on more or less implicit assumptions about an either-or rather than a more-or-less of these forms of government...

  4. OKBL: A language for representing object oriented knowledge

    International Nuclear Information System (INIS)

    Matsumoto, Y.; Sugiyai, I.; Ishikawa, K.

    1984-01-01

    Industrial system is operated by using numerous ''operator's knowledge'' about the system. Each knowledge can be regarded as an object and is represented and maintained as an 'ACTOR' and written in a language based on the actor concept. OKBL (Object Oriented Operational KnowledgeBase Management Language) is the language proposed here for this purpose and used in OKBS (a system based on OKBL). The OKBS inference mechanism on the knowledgebase written in OKBL is implemented by message passings among ACTORs. OKBS has been applied to the guidance system for the operators of electric power dispatch control stations

  5. Retention performance of green roofs in representative climates worldwide

    Science.gov (United States)

    Viola, F.; Hellies, M.; Deidda, R.

    2017-10-01

    The ongoing process of global urbanization contributes to an increase in stormwater runoff from impervious surfaces, threatening also water quality. Green roofs have been proved to be innovative stormwater management measures to partially restore natural states, enhancing interception, infiltration and evapotranspiration fluxes. The amount of water that is retained within green roofs depends not only on their depth, but also on the climate, which drives the stochastic soil moisture dynamic. In this context, a simple tool for assessing performance of green roofs worldwide in terms of retained water is still missing and highly desirable for practical assessments. The aim of this work is to explore retention performance of green roofs as a function of their depth and in different climate regimes. Two soil depths are investigated, one representing the intensive configuration and another representing the extensive one. The role of the climate in driving water retention has been represented by rainfall and potential evapotranspiration dynamics. A simple conceptual weather generator has been implemented and used for stochastic simulation of daily rainfall and potential evapotranspiration. Stochastic forcing is used as an input of a simple conceptual hydrological model for estimating long-term water partitioning between rainfall, runoff and actual evapotranspiration. Coupling the stochastic weather generator with the conceptual hydrological model, we assessed the amount of rainfall diverted into evapotranspiration for different combinations of annual rainfall and potential evapotranspiration in five representative climatic regimes. Results quantified the capabilities of green roofs in retaining rainfall and consequently in reducing discharges into sewer systems at an annual time scale. The role of substrate depth has been recognized to be crucial in determining green roofs retention performance, which in general increase from extensive to intensive settings. Looking at the

  6. Analysis of Mental Processes Represented in Models of Artificial Consciousness

    Directory of Open Access Journals (Sweden)

    Luana Folchini da Costa

    2013-12-01

    Full Text Available The Artificial Consciousness concept has been used in the engineering area as being an evolution of the Artificial Intelligence. However, consciousness is a complex subject and often used without formalism. As a main contribution, in this work one proposes an analysis of four recent models of artificial consciousness published in the engineering area. The mental processes represented by these models are highlighted and correlations with the theoretical perspective of cognitive psychology are made. Finally, considerations about consciousness in such models are discussed.

  7. Object-Relational Management of Multiply Represented Geographic Entities

    DEFF Research Database (Denmark)

    Friis-Christensen, Anders; Jensen, Christian Søndergaard

    2003-01-01

    Multiple representation occurs when information about the same geographic entity is represented electronically more than once. This occurs frequently in practice, and it invariably results in the occurrence of inconsistencies among the different representations. We propose to resolve this situation...... by introducing a multiple representation management system (MRMS), the schema of which includes rules that specify how to identify representations of the same entity, rules that specify consistency requirements, and rules used to restore consistency when necessary. In this paper, we demonstrate by means...

  8. The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project

    OpenAIRE

    Hudson, L. N.; Newbold, T.; Contu, S.; Hill, S. L.; Lysenko, I.; De Palma, A.; Phillips, H. R.; Alhusseini, T. I.; Bedford, F. E.; Bennett, D. J.; Booth, H.; Burton, V. J.; Chng, C. W.; Choimes, A.; Correia, D. L.

    2017-01-01

    The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make free...

  9. MANAGING MULTICULTURAL PROJECT TEAMS

    Directory of Open Access Journals (Sweden)

    Cezar SCARLAT

    2014-06-01

    Full Text Available The article is based on literature review and authors’ own recent experience in managing multicultural project teams, in international environment. This comparative study considers two groups of projects: technical assistance (TA projects versus information technology (IT projects. The aim is to explore the size and structure of the project teams – according to the team formation and its lifecycle, and to identify some distinctive attributes of the project teams – both similarities and differences between the above mentioned types of projects. Distinct focus of the research is on the multiculturalism of the project teams: how the cultural background of the team members influences the team performance and team management. Besides the results of the study are the managerial implications: how the team managers could soften the cultural clash, and avoid inter-cultural misunderstandings and even conflicts – in order to get a better performance. Some practical examples are provided as well.

  10. Construction project management handbook.

    Science.gov (United States)

    2012-03-01

    The purpose of the FTA Construction Project Management Handbook is to provide guidelines for use by public transit agencies (Agen-cies) undertaking substantial construction projects, either for the first time or with little prior experience with cons...

  11. BioProject

    Data.gov (United States)

    U.S. Department of Health & Human Services — The BioProject database provides an organizational framework to access information about research projects with links to data that have been or will be deposited...

  12. The Phebus FP project

    International Nuclear Information System (INIS)

    Delchambre, P.; Von der Hardt, P.

    1989-01-01

    This report summarizes the pre-project studies concerning the PHEBUS FP facility. After recalling the programme objectives, it describes the projected modifications to the PHEBUS reactor, outlines new installations and justifies the selected options

  13. Number projection method

    International Nuclear Information System (INIS)

    Kaneko, K.

    1987-01-01

    A relationship between the number projection and the shell model methods is investigated in the case of a single-j shell. We can find a one-to-one correspondence between the number projected and the shell model states

  14. Successful project management

    CERN Document Server

    Young, Trevor L

    2016-01-01

    Successful Project Management, 5th edition, is an essential guide for anyone who wants to improve the success rate of their projects. It will help managers to maintain a balance between the demands of the customer, the project, the team and the organization. Covering the more technical aspects of a project from start to completion it contains practised and tested techniques, covering project conception and start-up, how to manage stake holders, effective risk management, project planning and launch and execution. Also including a brand new glossary of key terms, it provides help with evaluating your project as well as practical checklists and templates to ensure success for any ambitious project manager. With over one million copies sold, the hugely popular Creating Success series covers a wide variety of topic, with the latest editions including new chapters such as Tough Conversations and Treating People Right. This indispensable business skills collection is suited to a variety of roles, from someone look...

  15. Unicycle Project Report

    OpenAIRE

    Thomson, S

    2010-01-01

    The Unicycle project implemented an institutional Open Educational Resource repository with a view to ensuring sustainability in approach by embedding OER as an Assessment, Learning and Teaching strategy. This is the final submitted report for the project.

  16. Collaborative Contracting in Projects

    NARCIS (Netherlands)

    Suprapto, M.

    2016-01-01

    Project practitioners have increasingly recognized the importance of collaborative relationships to ensure successful executions of projects. However, the ability to sustain and consistenly drive real collaborative attitudes and behavior for achieving the desired outcomes remains of enduring

  17. Project Tasks in Robotics

    DEFF Research Database (Denmark)

    Sørensen, Torben; Hansen, Poul Erik

    1998-01-01

    Description of the compulsary project tasks to be carried out as a part of DTU course 72238 Robotics......Description of the compulsary project tasks to be carried out as a part of DTU course 72238 Robotics...

  18. Venezuela's Bolivarian Schools Project.

    Science.gov (United States)

    Diaz, Maria Magnolia Santamaria

    2002-01-01

    Discusses efforts by the Venezuelan government to improve the nation's school infrastructure through the Bolivarian Schools Project administered by the Ministry of Education, Culture and Sport. The project set educational principles which are guiding current school building efforts. (EV)

  19. Project management process.

    Science.gov (United States)

    2007-03-01

    This course provides INDOT staff with foundational knowledge and skills in project management principles and methodologies. INDOTs project management processes provide the tools for interdisciplinary teams to efficiently and effectively deliver pr...

  20. The Alzheimer's Project

    Science.gov (United States)

    ... Navigation Bar Home Current Issue Past Issues The Alzheimer's Project Past Issues / Spring 2009 Table of Contents ... of this page please turn Javascript on. The Alzheimer's Project A 4-Part Documentary Series Starting May ...