Project Solo; Newsletter Number Twenty.
Pittsburgh Univ., PA. Project Solo.
Three Project Solo modules are presented. They are designed to teach the concepts of elementary matrix operation, matrix multiplication, and finite-state automata. Together with the module on communication matrices from Newsletter #17 they form a well motivated but structured path to expertise in this area. (JY)
Extra! Extra! Read All about It! How to Construct a Newsletter: A Student Project
Renard, Monika; Tracy, Kay
2011-01-01
This article discusses a student project that highlights the value of printed employee newsletters as an internal communication tool for organizations. The project provides specific information and directions on how to develop an employee newsletter on human resource topics. Microsoft Word 2007 is used for newsletter formatting. The article also…
Housing and maintenance of Ambystoma mexicanum, the Mexican axolotl.
Farkas, Johanna E; Monaghan, James R
2015-01-01
The aim of this paper is to assemble a significant amount of information on Ambystoma mexicanum, the axolotl salamander, to assist in the basic knowledge needed to raise, breed, and study most aspects of axolotl biology. It is important to understand the basic biology of the axolotl in order to make informed decisions on their proper care and use in experiments. Therefore, we will provide necessary information to the non-herpetologist that will assist in their study of this unique and fascinating animal. We also aim to provide a resource on the general anatomy, behavior, and experimental tips specific to the Mexican axolotl that will be of use to most axolotl laboratories. Axolotls have been actively researched since the 1860s, giving testament to their relatively straightforward maintenance and their versatility as an animal model for development and regeneration. Interest in using the axolotl in laboratory research has grown tremendously over the past decade, so dedicated resources to support the study of this species are needed and encouraged.
Thyroxine-induced metamorphosis in the axolotl (Ambystoma mexicanum).
Coots, Peggy S; Seifert, Ashley W
2015-01-01
The axolotl (Ambystoma mexicanum) has remained an important model for regeneration and developmental biology for over a century. Although axolotls in captive-bred colonies usually exist in an aquatic form, they retain the ability to undergo metamorphosis following exposure to thyroid hormone. Here we present a robust method for inducing metamorphosis in adult axolotls that results in high survivability and produces terrestrial animals that can be maintained in long-term captivity.
An introduction to the Mexican axolotl (Ambystoma mexicanum).
Gresens, Jill
2004-10-01
A number of unusual traits, including a remarkable capacity for wound healing and limb regeneration, make the axolotl an interesting animal model. The author provides an overview of axolotl care and use in biomedical research.
Forever young: Endocrinology of paedomorphosis in the Mexican axolotl (Ambystoma mexicanum).
De Groef, Bert; Grommen, Sylvia V H; Darras, Veerle M
2018-05-16
The Mexican axolotl (Ambystoma mexicanum) is a salamander species that does not undergo metamorphosis, resulting in the retention of juvenile characteristics in the mature breeding stage (paedomorphosis). Here we review the endocrinological studies investigating the proximate cause of axolotl paedomorphosis with a focus on the hypothalamo-pituitary-thyroid (HPT) axis. It is well established that axolotl paedomorphosis is a consequence of low activity of the HPT axis. The pituitary hormone thyrotropin (TSH) is capable of inducing metamorphosis in the axolotl, which indicates that all processes and interactions in the HPT axis below the pituitary level are functional, but that TSH release is impaired. In metamorphosing species, TSH secretion is largely controlled by the hypothalamic neuropeptide corticotropin-releasing hormone (CRH), which seems to have lost its thyrotropic activity in the axolotl. However, preliminary experiments have not yet confirmed a role for faulty CRH signalling in axolotl paedomorphosis. Other hypothalamic factors and potential pituitary inhibitors need to be investigated to identify their roles in amphibian metamorphosis and axolotl paedomorphosis. Copyright © 2018 Elsevier Inc. All rights reserved.
International Nuclear Information System (INIS)
Batandjieva, Borislava
2001-12-01
This issue of the ISAM newsletter informs on the ISAM Co-ordinating Group Meeting held in September 2000 at the IAEA Headquarters in Vienna and provides a brief overview of the final report on Safety Assessment Methodologies for Near Surface Waste Disposal Facilities. The newsletter announces the new IAEA co-ordinated research project - Application of Safety Assessment Methodologies for Near Surface Disposal Facilities (ASAM). The newsletter also briefs on the related IAEA activities
Transcriptional landscapes of Axolotl (Ambystoma mexicanum).
Caballero-Pérez, Juan; Espinal-Centeno, Annie; Falcon, Francisco; García-Ortega, Luis F; Curiel-Quesada, Everardo; Cruz-Hernández, Andrés; Bako, Laszlo; Chen, Xuemei; Martínez, Octavio; Alberto Arteaga-Vázquez, Mario; Herrera-Estrella, Luis; Cruz-Ramírez, Alfredo
2018-01-15
The axolotl (Ambystoma mexicanum) is the vertebrate model system with the highest regeneration capacity. Experimental tools established over the past 100 years have been fundamental to start unraveling the cellular and molecular basis of tissue and limb regeneration. In the absence of a reference genome for the Axolotl, transcriptomic analysis become fundamental to understand the genetic basis of regeneration. Here we present one of the most diverse transcriptomic data sets for Axolotl by profiling coding and non-coding RNAs from diverse tissues. We reconstructed a population of 115,906 putative protein coding mRNAs as full ORFs (including isoforms). We also identified 352 conserved miRNAs and 297 novel putative mature miRNAs. Systematic enrichment analysis of gene expression allowed us to identify tissue-specific protein-coding transcripts. We also found putative novel and conserved microRNAs which potentially target mRNAs which are reported as important disease candidates in heart and liver. Copyright © 2017 Elsevier Inc. All rights reserved.
Safi, Rachid; Bertrand, Stéphanie; Marchand, Oriane; Duffraisse, Marilyne; de Luze, Amaury; Vanacker, Jean-Marc; Maraninchi, Marie; Margotat, Alain; Demeneix, Barbara; Laudet, Vincent
2004-02-01
Neotenic amphibians such as the axolotl (Ambystoma mexicanum) are often unable to undergo metamorphosis under natural conditions. It is thought that neoteny represents a deviation from the standard course of amphibian ontogeny, affecting the thyroid axis at different levels from the central nervous system to peripheral organs. Thyroid hormone receptors (TRs) that bind the thyroid hormone (TH) T(3) have been described in axolotl. However, the full sequences of TR were needed to better characterize the TH response and to be able to assess their functional capacity at the molecular level. We report that each of the alpha and beta axolotl TRs bind both DNA and TH, and they activate transcription in response to TH in a mammalian cell-based transient transfection assay. Moreover, both TRs are expressed in axolotl tissues. Interestingly, each TR gene generates alternatively spliced isoforms, harboring partial or total deletions of the ligand-binding domain, which are expressed in vivo. Further, we found that in the axolotl, TH regulates the expression of stromelysin 3 and collagenase 3, which are TH target genes in Xenopus. Taken together, these results suggest that axolotl TRs are functional and that the molecular basis of neoteny in the axolotl is not linked to a major defect in TH response in peripheral tissues.
Lens regeneration in axolotl: new evidence of developmental plasticity
Directory of Open Access Journals (Sweden)
Suetsugu-Maki Rinako
2012-12-01
Full Text Available Abstract Background Among vertebrates lens regeneration is most pronounced in newts, which have the ability to regenerate the entire lens throughout their lives. Regeneration occurs from the dorsal iris by transdifferentiation of the pigment epithelial cells. Interestingly, the ventral iris never contributes to regeneration. Frogs have limited lens regeneration capacity elicited from the cornea during pre-metamorphic stages. The axolotl is another salamander which, like the newt, regenerates its limbs or its tail with the spinal cord, but up until now all reports have shown that it does not regenerate the lens. Results Here we present a detailed analysis during different stages of axolotl development, and we show that despite previous beliefs the axolotl does regenerate the lens, however, only during a limited time after hatching. We have found that starting at stage 44 (forelimb bud stage lens regeneration is possible for nearly two weeks. Regeneration occurs from the iris but, in contrast to the newt, regeneration can be elicited from either the dorsal or the ventral iris and, occasionally, even from both in the same eye. Similar studies in the zebra fish concluded that lens regeneration is not possible. Conclusions Regeneration of the lens is possible in the axolotl, but differs from both frogs and newts. Thus the axolotl iris provides a novel and more plastic strategy for lens regeneration.
Limb Regeneration in Axolotl: Is It Superhealing?
Directory of Open Access Journals (Sweden)
Stéphane Roy
2006-01-01
Full Text Available The ability of axolotls to regenerate their limbs is almost legendary. In fact, urodeles such as the axolotl are the only vertebrates that can regenerate multiple structures like their limbs, jaws, tail, spinal cord, and skin (the list goes on throughout their lives. It is therefore surprising to realize, although we have known of their regenerative potential for over 200 years, how little we understand the mechanisms behind this achievement of adult tissue morphogenesis. Many observations can be drawn between regeneration and other disciplines such as development and wound healing. In this review, we present new developments in functional analysis that will help to address the role of specific genes during the process of regeneration. We also present an analysis of the resemblance between wound healing and regeneration, and discuss whether axolotls are superhealers. A better understanding of these animals' regenerative capacity could lead to major benefits by providing regenerative medicine with directions on how to develop therapeutic approaches leading to regeneration in humans.
Generation of axolotl hematopoietic chimeras
Directory of Open Access Journals (Sweden)
David Lopez
2015-02-01
Full Text Available Wound repair is an extremely complex process that requires precise coordination between various cell types including immune cells. Unfortunately, in mammals this usually results in scar formation instead of restoration of the original fully functional tissue, otherwise known as regeneration. Various animal models like frogs and salamanders are currently being studied to determine the intracellular and intercellular pathways, controlled by gene expression, that elicit cell proliferation, differentiation, and migration of cells during regenerative healing. Now, the necessary genetic tools to map regenerative pathways are becoming available for the axolotl salamander, thus allowing comparative studies between scarring and regeneration. Here, we describe in detail three methods to produce axolotl hematopoietic cell-tagged chimeras for the study of hematopoiesis and regeneration.
Khattak, Shahryar; Murawala, Prayag; Andreas, Heino; Kappert, Verena; Schuez, Maritta; Sandoval-Guzmán, Tatiana; Crawford, Karen; Tanaka, Elly M
2014-03-01
The axolotl (Mexican salamander, Ambystoma mexicanum) has become a very useful model organism for studying limb and spinal cord regeneration because of its high regenerative capacity. Here we present a protocol for successfully mating and breeding axolotls in the laboratory throughout the year, for metamorphosing axolotls by a single i.p. injection and for axolotl transgenesis using I-SceI meganuclease and the mini Tol2 transposon system. Tol2-mediated transgenesis provides different features and advantages compared with I-SceI-mediated transgenesis, and it can result in more than 30% of animals expressing the transgene throughout their bodies so that they can be directly used for experimentation. By using Tol2-mediated transgenesis, experiments can be performed within weeks (e.g., 5-6 weeks for obtaining 2-3-cm-long larvae) without the need to establish germline transgenic lines (which take 12-18 months). In addition, we describe here tamoxifen-induced Cre-mediated recombination in transgenic axolotls.
Novel axolotl cardiac function analysis method using magnetic resonance imaging.
Directory of Open Access Journals (Sweden)
Pedro Gomes Sanches
Full Text Available The salamander axolotl is capable of complete regeneration of amputated heart tissue. However, non-invasive imaging tools for assessing its cardiac function were so far not employed. In this study, cardiac magnetic resonance imaging is introduced as a non-invasive technique to image heart function of axolotls. Three axolotls were imaged with magnetic resonance imaging using a retrospectively gated Fast Low Angle Shot cine sequence. Within one scanning session the axolotl heart was imaged three times in all planes, consecutively. Heart rate, ejection fraction, stroke volume and cardiac output were calculated using three techniques: (1 combined long-axis, (2 short-axis series, and (3 ultrasound (control for heart rate only. All values are presented as mean ± standard deviation. Heart rate (beats per minute among different animals was 32.2±6.0 (long axis, 30.4±5.5 (short axis and 32.7±4.9 (ultrasound and statistically similar regardless of the imaging method (p > 0.05. Ejection fraction (% was 59.6±10.8 (long axis and 48.1±11.3 (short axis and it differed significantly (p = 0.019. Stroke volume (μl/beat was 133.7±33.7 (long axis and 93.2±31.2 (short axis, also differed significantly (p = 0.015. Calculations were consistent among the animals and over three repeated measurements. The heart rate varied depending on depth of anaesthesia. We described a new method for defining and imaging the anatomical planes of the axolotl heart and propose one of our techniques (long axis analysis may prove useful in defining cardiac function in regenerating axolotl hearts.
Musashi and Plasticity of Xenopus and Axolotl Spinal Cord Ependymal Cells
Chernoff, Ellen A. G.; Sato, Kazuna; Salfity, Hai V. N.; Sarria, Deborah A.; Belecky-Adams, Teri
2018-01-01
The differentiated state of spinal cord ependymal cells in regeneration-competent amphibians varies between a constitutively active state in what is essentially a developing organism, the tadpole of the frog Xenopus laevis, and a quiescent, activatable state in a slowly growing adult salamander Ambystoma mexicanum, the Axolotl. Ependymal cells are epithelial in intact spinal cord of all vertebrates. After transection, body region ependymal epithelium in both Xenopus and the Axolotl disorganizes for regenerative outgrowth (gap replacement). Injury-reactive ependymal cells serve as a stem/progenitor cell population in regeneration and reconstruct the central canal. Expression patterns of mRNA and protein for the stem/progenitor cell-maintenance Notch signaling pathway mRNA-binding protein Musashi (msi) change with life stage and regeneration competence. Msi-1 is missing (immunohistochemistry), or at very low levels (polymerase chain reaction, PCR), in both intact regeneration-competent adult Axolotl cord and intact non-regeneration-competent Xenopus tadpole (Nieuwkoop and Faber stage 62+, NF 62+). The critical correlation for successful regeneration is msi-1 expression/upregulation after injury in the ependymal outgrowth and stump-region ependymal cells. msi-1 and msi-2 isoforms were cloned for the Axolotl as well as previously unknown isoforms of Xenopus msi-2. Intact Xenopus spinal cord ependymal cells show a loss of msi-1 expression between regeneration-competent (NF 50–53) and non-regenerating stages (NF 62+) and in post-metamorphosis froglets, while msi-2 displays a lower molecular weight isoform in non-regenerating cord. In the Axolotl, embryos and juveniles maintain Msi-1 expression in the intact cord. In the adult Axolotl, Msi-1 is absent, but upregulates after injury. Msi-2 levels are more variable among Axolotl life stages: rising between late tailbud embryos and juveniles and decreasing in adult cord. Cultures of regeneration-competent Xenopus tadpole
Musashi and Plasticity of Xenopus and Axolotl Spinal Cord Ependymal Cells
Directory of Open Access Journals (Sweden)
Ellen A. G. Chernoff
2018-02-01
Full Text Available The differentiated state of spinal cord ependymal cells in regeneration-competent amphibians varies between a constitutively active state in what is essentially a developing organism, the tadpole of the frog Xenopus laevis, and a quiescent, activatable state in a slowly growing adult salamander Ambystoma mexicanum, the Axolotl. Ependymal cells are epithelial in intact spinal cord of all vertebrates. After transection, body region ependymal epithelium in both Xenopus and the Axolotl disorganizes for regenerative outgrowth (gap replacement. Injury-reactive ependymal cells serve as a stem/progenitor cell population in regeneration and reconstruct the central canal. Expression patterns of mRNA and protein for the stem/progenitor cell-maintenance Notch signaling pathway mRNA-binding protein Musashi (msi change with life stage and regeneration competence. Msi-1 is missing (immunohistochemistry, or at very low levels (polymerase chain reaction, PCR, in both intact regeneration-competent adult Axolotl cord and intact non-regeneration-competent Xenopus tadpole (Nieuwkoop and Faber stage 62+, NF 62+. The critical correlation for successful regeneration is msi-1 expression/upregulation after injury in the ependymal outgrowth and stump-region ependymal cells. msi-1 and msi-2 isoforms were cloned for the Axolotl as well as previously unknown isoforms of Xenopus msi-2. Intact Xenopus spinal cord ependymal cells show a loss of msi-1 expression between regeneration-competent (NF 50–53 and non-regenerating stages (NF 62+ and in post-metamorphosis froglets, while msi-2 displays a lower molecular weight isoform in non-regenerating cord. In the Axolotl, embryos and juveniles maintain Msi-1 expression in the intact cord. In the adult Axolotl, Msi-1 is absent, but upregulates after injury. Msi-2 levels are more variable among Axolotl life stages: rising between late tailbud embryos and juveniles and decreasing in adult cord. Cultures of regeneration
Guelke, Eileen; Bucan, Vesna; Liebsch, Christina; Lazaridis, Andrea; Radtke, Christine; Vogt, Peter M; Reimers, Kerstin
2015-04-10
For the precise quantitative RT-PCR normalization a set of valid reference genes is obligatory. Moreover have to be taken into concern the experimental conditions as they bias the regulation of reference genes. Up till now, no reference targets have been described for the axolotl (Ambystoma mexicanum). In a search in the public database SalSite for genetic information of the axolotl we identified fourteen presumptive reference genes, eleven of which were further tested for their gene expression stability. This study characterizes the expressional patterns of 11 putative endogenous control genes during axolotl limb regeneration and in an axolotl tissue panel. All 11 reference genes showed variable expression. Strikingly, ACTB was to be found most stable expressed in all comparative tissue groups, so we reason it to be suitable for all different kinds of axolotl tissue-type investigations. Moreover do we suggest GAPDH and RPLP0 as suitable for certain axolotl tissue analysis. When it comes to axolotl limb regeneration, a validated pair of reference genes is ODC and RPLP0. With these findings, new insights into axolotl gene expression profiling might be gained. Copyright © 2015 Elsevier B.V. All rights reserved.
Misexpression experiment of Tbx5 in axolotl (Ambystoma mexicanum) hindlimb blastema.
Shimokawa, Takashi; Kominami, Rieko; Yasutaka, Satoru; Shinohara, Harumichi
2013-01-01
Axolotls (Ambystoma mexicanum) have the ability to regenerate amputated limbs throughout their life span. In the present study, we attempted to elucidate how axolotls can specify limb type correctly during the regeneration process. We misexpressed Tbx5 in regenerating hindlimb blastema, and consequently a forelimb-like hindlimb regenerated from the hindlimb blastema. On the other hand, no change was observed in Tbx5-overexpressing forelimb blastema, and thus we considered that Tbx5 plays a key role in the specification of forelimb during the regeneration process of axolotl limbs. However, axolotls' fore- and hindlimbs have very similar structures except for the number of fingers, and it was very difficult to judge whether the forelimb-like regenerate was a true forelimb or merely a forelimb-like hindlimb. Therefore, in order to confirm our conclusion, we have to investigate other genes that are expressed differentially between fore- and hindlimbs in future experiments.
ISOLATION AND CHARACTERIZATION OF AXOLOTL NPDC-1 AND ITS EFFECTS ON RETINOIC ACID RECEPTOR SIGNALING
Theodosiou, Maria; Monaghan, James R; Spencer, Michael L; Voss, S Randal; Noonan, Daniel J
2009-01-01
Retinoic acid, a key morphogen in early vertebrate development and tissue regeneration, mediates its effects through the binding of receptors that act as ligand-induced transcription factors. These binding events function to recruit an array of transcription co-regulatory proteins to specific gene promoters. One such co-regulatory protein, neuronal proliferation and differentiation control-1 (NPDC-1), is broadly expressed during mammalian development and functions as an in vitro repressor of retinoic acid receptor (RAR)-mediated transcription. To obtain comparative and developmental insights about NPDC-1 function, we cloned the axolotl (Ambystoma mexicanum) orthologue and measured transcript abundances among tissues sampled during the embryonic and juvenile phases of development, and also during spinal cord regeneration. Structurally, the axolotl orthologue of NPDC-1 retained sequence identity to mammalian sequences in all functional domains. Functionally, we observed that axolotl NPDC-1 mRNA expression peaked late in embryogenesis, with highest levels of expression occurring during the time of limb development, a process regulated by retinoic acid signaling. Also similar to what has been observed in mammals, axolotl NPDC-1 directly interacts with axolotl RAR, modulates axolotl RAR DNA binding, and represses cell proliferation and axolotl RAR-mediated gene transcription. These data justify axolotl as a model to further investigate NPDC-1 and its role in regulating retinoic acid signaling. PMID:17331771
A histological atlas of the tissues and organs of neotenic and metamorphosed axolotl.
Demircan, Turan; İlhan, Ayşe Elif; Aytürk, Nilüfer; Yıldırım, Berna; Öztürk, Gürkan; Keskin, İlknur
2016-09-01
Axolotl (Ambystoma Mexicanum) has been emerging as a promising model in stem cell and regeneration researches due to its exceptional regenerative capacity. Although it represents lifelong lasting neoteny, induction to metamorphosis with thyroid hormones (THs) treatment advances the utilization of Axolotl in various studies. It has been reported that amphibians undergo anatomical and histological remodeling during metamorphosis and this transformation is crucial for adaptation to terrestrial conditions. However, there is no comprehensive histological investigation regarding the morphological alterations of Axolotl organs and tissues throughout the metamorphosis. Here, we reveal the histological differences or resemblances between the neotenic and metamorphic axolotl tissues. In order to examine structural features and cellular organization of Axolotl organs, we performed Hematoxylin & Eosin, Luxol-Fast blue, Masson's trichrome, Alcian blue, Orcein and Weigart's staining. Stained samples from brain, gallbladder, heart, intestine, liver, lung, muscle, skin, spleen, stomach, tail, tongue and vessel were analyzed under the light microscope. Our findings contribute to the validation of the link between newly acquired functions and structural changes of tissues and organs as observed in tail, skin, gallbladder and spleen. We believe that this descriptive work provides new insights for a better histological understanding of both neotenic and metamorphic Axolotl tissues. Copyright © 2016 Elsevier GmbH. All rights reserved.
Continuous growth of the motor system in the axolotl
International Nuclear Information System (INIS)
Holder, N.; Clarke, J.D.; Stephens, N.; Wilson, S.W.; Orsi, C.; Bloomer, T.; Tonge, D.A.
1991-01-01
During growth of the axolotl, motor neurons, and muscle fibres are added to the motor system. By double labelling neurons with tritiated thymidine and retrogradely transported HRP, we show that some motor neurons are born at postembryonic stages. Further analysis of motor neurons with the aid of HRP reveals this population of newly born cells relatively frequently in small (5-7 cm long) axolotls, but only rarely in large (7-13 cm long) axolotls. Evidence is presented that suggests that these immature cells are in the process of migrating from close to the ependyma out to the ventral horn. HRP transport also reveals growth cones of advancing axons within spinal nerves in animals up to 6 cm in length. Cell counts by light and electron microscopic methods show that muscle fibres are generated throughout larval life in the iliotibialis, a typical limb muscle. This analysis provides data consistent with the notion that new muscle fibres are added from a localised growth zone situated at the superficial edge of the muscle. These results are discussed in terms of the correlation between continuous growth of the motor system and the ability of the axolotl to functionally repair lesions to the peripheral nervous system
Transforming growth factor: beta signaling is essential for limb regeneration in axolotls.
Directory of Open Access Journals (Sweden)
Mathieu Lévesque
2007-11-01
Full Text Available Axolotls (urodele amphibians have the unique ability, among vertebrates, to perfectly regenerate many parts of their body including limbs, tail, jaw and spinal cord following injury or amputation. The axolotl limb is the most widely used structure as an experimental model to study tissue regeneration. The process is well characterized, requiring multiple cellular and molecular mechanisms. The preparation phase represents the first part of the regeneration process which includes wound healing, cellular migration, dedifferentiation and proliferation. The redevelopment phase represents the second part when dedifferentiated cells stop proliferating and redifferentiate to give rise to all missing structures. In the axolotl, when a limb is amputated, the missing or wounded part is regenerated perfectly without scar formation between the stump and the regenerated structure. Multiple authors have recently highlighted the similarities between the early phases of mammalian wound healing and urodele limb regeneration. In mammals, one very important family of growth factors implicated in the control of almost all aspects of wound healing is the transforming growth factor-beta family (TGF-beta. In the present study, the full length sequence of the axolotl TGF-beta1 cDNA was isolated. The spatio-temporal expression pattern of TGF-beta1 in regenerating limbs shows that this gene is up-regulated during the preparation phase of regeneration. Our results also demonstrate the presence of multiple components of the TGF-beta signaling machinery in axolotl cells. By using a specific pharmacological inhibitor of TGF-beta type I receptor, SB-431542, we show that TGF-beta signaling is required for axolotl limb regeneration. Treatment of regenerating limbs with SB-431542 reveals that cellular proliferation during limb regeneration as well as the expression of genes directly dependent on TGF-beta signaling are down-regulated. These data directly implicate TGF
The newsletter 'European Research in Radiological Sciences'
International Nuclear Information System (INIS)
Pihet, P.; D'Errico, F.; Doerr, W.; Gruenberger, M.; Schofield, P.
2004-01-01
The newsletter 'European Research in Radiological Sciences' is jointly published by the European Late Effects Project Group and the European Radiation Dosimetry Group to disseminate information about research projects and activities carried out under the EURATOM Framework Programme. Since May 2003, the Newsletter is operated interactively from the Internet. The new site uses a dedicated database that automatically generates HTML pages. This system developed at the Univ. of Cambridge provides an innovative approach to improve the dissemination of project information. (authors)
Demircan, Turan; Keskin, Ilknur; Dumlu, Seda Nilgün; Aytürk, Nilüfer; Avşaroğlu, Mahmut Erhan; Akgün, Emel; Öztürk, Gürkan; Baykal, Ahmet Tarık
2017-01-01
Salamander axolotl has been emerging as an important model for stem cell research due to its powerful regenerative capacity. Several advantages, such as the high capability of advanced tissue, organ, and appendages regeneration, promote axolotl as an ideal model system to extend our current understanding on the mechanisms of regeneration. Acknowledging the common molecular pathways between amphibians and mammals, there is a great potential to translate the messages from axolotl research to mammalian studies. However, the utilization of axolotl is hindered due to the lack of reference databases of genomic, transcriptomic, and proteomic data. Here, we introduce the proteome analysis of the axolotl tail section searched against an mRNA-seq database. We translated axolotl mRNA sequences to protein sequences and annotated these to process the LC-MS/MS data and identified 1001 nonredundant proteins. Functional classification of identified proteins was performed by gene ontology searches. The presence of some of the identified proteins was validated by in situ antibody labeling. Furthermore, we have analyzed the proteome expressional changes postamputation at three time points to evaluate the underlying mechanisms of the regeneration process. Taken together, this work expands the proteomics data of axolotl to contribute to its establishment as a fully utilized model. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
The Mexican Axolotl in Schools
Thomas, R. M.
1976-01-01
Suggests and describes laboratory activities in which the Mexican axolotl (Ambystoma mexicanum Shaw) is used, including experiments in embryology and early development, growth and regeneration, neoteny and metamorphosis, genetics and coloration, anatomy and physiology, and behavior. Discusses care and maintenance of animals. (CS)
A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors
Directory of Open Access Journals (Sweden)
Donald M. Bryant
2017-01-01
Full Text Available Mammals have extremely limited regenerative capabilities; however, axolotls are profoundly regenerative and can replace entire limbs. The mechanisms underlying limb regeneration remain poorly understood, partly because the enormous and incompletely sequenced genomes of axolotls have hindered the study of genes facilitating regeneration. We assembled and annotated a de novo transcriptome using RNA-sequencing profiles for a broad spectrum of tissues that is estimated to have near-complete sequence information for 88% of axolotl genes. We devised expression analyses that identified the axolotl orthologs of cirbp and kazald1 as highly expressed and enriched in blastemas. Using morpholino anti-sense oligonucleotides, we find evidence that cirbp plays a cytoprotective role during limb regeneration whereas manipulation of kazald1 expression disrupts regeneration. Our transcriptome and annotation resources greatly complement previous transcriptomic studies and will be a valuable resource for future research in regenerative biology.
Eisthen, Heather L; Krause, Brianne Chung
2012-05-01
Axolotls (Ambystoma mexicanum) are aquatic salamanders that are widely used in research. Axolotls have been bred in laboratories for nearly 150 years, yet little is known about the basic biology of reproduction in these animals. We investigated the effects of changing day length, time of year, and food availability on levels of circulating estradiol and androgens in adult female and male axolotls, respectively. In addition, we examined the effects of these variables on the mass of ovaries, oviducts, and eggs in females and on mass of testes in males relative to each individual's body weight, to calculate a form of gonadosomatic index (GSI). In both sexes, GSI was not correlated with levels of circulating steroids. In female axolotls, estradiol levels were influenced by food availability, changes in day length, and season, even when animals were held at a constant temperature and day length was decorrelated with calendar date. In addition, the mass of ovaries, oviducts, and eggs varied seasonally, peaking in the winter months and declining during the summer months, even though our animals were not breeding and shedding eggs. In males, levels of androgens appeared to vary independently of external conditions, but GSI varied dramatically with changes in day length. These results suggest that reproduction in axolotls may vary seasonally, as it does in many other ambystomid species, although both male and female axolotls are capable of reproducing several times each year. The physiological basis of this ability remains enigmatic, given the indications of seasonality contained in our data. Copyright © 2012 Elsevier Inc. All rights reserved.
Eleven Tribes Jump START Clean Energy Projects, Summer 2012 (Newsletter)
Energy Technology Data Exchange (ETDEWEB)
2012-06-01
This newsletter describes key activities of the DOE Office of Indian Energy Policy and Programs for Summer 2012. The U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) has selected 11 Tribes - five in Alaska and six in the contiguous United States - to receive on-the-ground technical support for community-based energy efficiency and renewable energy projects as part of DOE-IE's Strategic Technical Assistance Response Team (START) Program. START finalists were selected based on the clarity of their requests for technical assistance and the ability of START to successfully work with their projects or community. Technical experts from DOE and its National Renewable Energy Laboratory (NREL) will work directly with community-based project teams to analyze local energy issues and assist the Tribes in moving their projects forward. In Alaska, the effort will be bolstered by DOE-IE's partnership with the Denali Commission, which will provide additional assistance and expertise, as well as funding to fuel the Alaska START initiative.
Voss, S R; Shaffer, H B
2000-09-01
In many organisms metamorphosis allows for an ecologically important habitat-shift from water to land. However, in some salamanders an adaptive life cycle mode has evolved that is characterized by metamorphic failure (paedomorphosis); these species remain in the aquatic habitat throughout the life cycle. Perhaps the most famous example of metamorphic failure is the Mexican axolotl (Ambystoma mexicanum), which has become a focal species for developmental biology since it was introduced into laboratory culture in the 1800s. Our previous genetic linkage mapping analysis, using an interspecific crossing design, demonstrated that a major gene effect underlies the expression of metamorphic failure in laboratory stocks of the Mexican axolotl. Here, we repeated this experiment using A. mexicanum that were sampled directly from their natural habitat at Lake Xochimilco, Mexico. We found no significant association between the major gene and metamorphic failure when wild-caught axolotls were used in the experimental design, although there is evidence of a smaller genetic effect. Thus, there appears to be genetic variation among Mexican axolotls (and possibly A. tigrinum tigrinum) at loci that contribute to metamorphic failure. This result suggests a role for more than one mutation and possibly artificial selection in the evolution of the major gene effect in the laboratory Mexican axolotl.
Highly efficient targeted mutagenesis in axolotl using Cas9 RNA-guided nuclease
Flowers, G. Parker; Timberlake, Andrew T.; Mclean, Kaitlin C.; Monaghan, James R.; Crews, Craig M.
2014-01-01
Among tetrapods, only urodele salamanders, such as the axolotl Ambystoma mexicanum, can completely regenerate limbs as adults. The mystery of why salamanders, but not other animals, possess this ability has for generations captivated scientists seeking to induce this phenomenon in other vertebrates. Although many recent advances in molecular biology have allowed limb regeneration and tissue repair in the axolotl to be investigated in increasing detail, the molecular toolkit for the study of this process has been limited. Here, we report that the CRISPR-Cas9 RNA-guided nuclease system can efficiently create mutations at targeted sites within the axolotl genome. We identify individual animals treated with RNA-guided nucleases that have mutation frequencies close to 100% at targeted sites. We employ this technique to completely functionally ablate EGFP expression in transgenic animals and recapitulate developmental phenotypes produced by loss of the conserved gene brachyury. Thus, this advance allows a reverse genetic approach in the axolotl and will undoubtedly provide invaluable insight into the mechanisms of salamanders' unique regenerative ability. PMID:24764077
Courtship Pheromone Use in a Model Urodele, the Mexican Axolotl (Ambystoma mexicanum).
Maex, Margo; Van Bocxlaer, Ines; Mortier, Anneleen; Proost, Paul; Bossuyt, Franky
2016-02-04
Sex pheromones have been shown to constitute a crucial aspect of salamander reproduction. Until now, courtship pheromones of Salamandridae and Plethodontidae have been intensively studied, but information on chemical communication in other urodelan families is essentially lacking. The axolotl (Ambystoma mexicanum, Ambystomatidae) has a courtship display that suggests a key role for chemical communication in the orchestration of its sexual behavior, but no sex pheromones have yet been characterized from this species. Here we combined whole transcriptome analyses of the male cloaca with proteomic analyses of water in which axolotls were allowed to court to show that male axolotls secrete multiple ca. 20 kDa glycosylated sodefrin precursor-like factor (SPF) proteins during courtship. In combination with phylogenetic analyses, our data show that the male cloaca essentially secretes a courtship-specific clade of SPF proteins that is orthologous to salamandrid courtship pheromones. In addition, we identified an SPF protein for which no orthologs have been described from other salamanders so far. Overall, our study advocates a central role for SPF proteins during the courtship display of axolotls and adds knowledge on pheromone use in a previously unexplored deep evolutionary branch of salamander evolution.
Mutation breeding newsletter. No. 33
Energy Technology Data Exchange (ETDEWEB)
NONE
1989-01-01
This issue of the newsletter reports a number of research news and research abstracts on application of radiation induced mutation techniques to increase mutagenesis and mutation frequency in plant breeding projects.
Mutation breeding newsletter. No. 33
International Nuclear Information System (INIS)
1989-01-01
This issue of the newsletter reports a number of research news and research abstracts on application of radiation induced mutation techniques to increase mutagenesis and mutation frequency in plant breeding projects
Mutation breeding newsletter. No. 36
Energy Technology Data Exchange (ETDEWEB)
NONE
1990-07-01
This issue of the Newsletter presents abstracts and short communications of research results on radiation and chemical induced mutation breeding projects. Positive traits such as disease resistance and increased productivity are highlighted.
Mutation breeding newsletter. No. 34
International Nuclear Information System (INIS)
1989-07-01
This issue of the Newsletter presents abstracts and short communications of research results on radiation and chemical induced mutation breeding projects. Positive traits such as disease resistance and increased productivity are highlighted
Mutation breeding newsletter. No. 34
Energy Technology Data Exchange (ETDEWEB)
NONE
1989-07-01
This issue of the Newsletter presents abstracts and short communications of research results on radiation and chemical induced mutation breeding projects. Positive traits such as disease resistance and increased productivity are highlighted.
Mutation breeding newsletter. No. 36
International Nuclear Information System (INIS)
1990-07-01
This issue of the Newsletter presents abstracts and short communications of research results on radiation and chemical induced mutation breeding projects. Positive traits such as disease resistance and increased productivity are highlighted
ITER EDA newsletter. V. 6, no. 3
International Nuclear Information System (INIS)
1997-03-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter reports on the Central Solenoid Model Coil Project (Function, Objectives, Design, Project Management, Testing, Work Organization and Status). 8 figs, 2 tabs
Role of Myofibril-Inducing RNA in cardiac TnT expression in developing Mexican axolotl
Sferrazza, Gian-Franco; Zhang, Chi; Jia, Pingping; Lemanski, Sharon L.; Athauda, Gagani; Stassi, Alyssa; Halager, Kristine; Maier, Jennifer A.; Rueda-de-Leon, Elena; Gupta, Amit; Dube, Syamalima; Huang, Xupei; Prentice, Howard M.; Dube, Dipak K.; Lemanski, Larry F.
2007-01-01
The Mexican axolotl, Ambystoma mexicanum, has been a useful animal model to study heart development and cardiac myofibrillogenesis. A naturally-occurring recessive mutant, gene “c”, for cardiac non-function in the Mexican axolotl causes a failure of myofibrillogenesis due to a lack of tropomyosin expression in homozygous mutant (c/c) embryonic hearts.. Myofibril-Inducing RNA (MIR) rescues mutant hearts in vitro by promoting tropomyosin expression and myofibril formation thereafter. We have studied the effect of MIR on the expression of various isoforms of cardiac Troponin-T (cTnT), a component of the thin filament that binds with tropomyosin. Four alternatively spliced cTnT isoforms have been characterized from developing axolotl heart. The expression of various cTnT isoforms in normal, mutant, and mutant hearts corrected with MIR, is evaluated by real-time RT-PCR using isoform specific primer pairs; MIR affects the total transcription as well as the splicing of the cTnT in axolotl heart PMID:17408593
Experimentally induced metamorphosis in axolotls reduces regenerative rate and fidelity
Stier, Adrian C.; Michonneau, François; Smith, Matthew D.; Pasch, Bret; Maden, Malcolm
2014-01-01
Abstract While most tetrapods are unable to regenerate severed body parts, amphibians display a remarkable ability to regenerate an array of structures. Frogs can regenerate appendages as larva, but they lose this ability around metamorphosis. In contrast, salamanders regenerate appendages as larva, juveniles, and adults. However, the extent to which fundamental traits (e.g., metamorphosis, body size, aging, etc.) restrict regenerative ability remains contentious. Here we utilize the ability of normally paedomorphic adult axolotls (Ambystoma mexicanum) to undergo induced metamorphosis by thyroxine exposure to test how metamorphosis and body size affects regeneration in age‐matched paedomorphic and metamorphic individuals. We show that body size does not affect regeneration in adult axolotls, but metamorphosis causes a twofold reduction in regeneration rate, and lead to carpal and digit malformations. Furthermore, we find evidence that metamorphic blastemal cells may take longer to traverse the cell cycle and display a lower proliferative rate. This study identifies the axolotl as a powerful system to study how metamorphosis restricts regeneration independently of developmental stage, body size, and age; and more broadly how metamorphosis affects tissue‐specific changes. PMID:27499857
International Nuclear Information System (INIS)
2001-11-01
This ITER CTA newsletter comprises reports of Dr. P. Barnard, Iter Canada Chairman and CEO, about the progress of the first formal ITER negotiations and about the demonstration of details of Canada's bid on ITER workshops, and Dr. V. Vlasenkov, Project Board Secretary, about the meeting of the ITER CTA project board
Soils newsletter. V. 15, no. 1
International Nuclear Information System (INIS)
1992-07-01
The First Soils Newsletter of 1992 summarizes the status of the six coordinated research programs (CRPs) currently in progress and announces a new CRP on ''The Use of Nuclear and Related Techniques in the Evaluation of the Agronomic Effectiveness of Phosphate Fertilizers, in Particular Rock Phosphates''. The first Research Coordination Meeting on ''The Use of Nuclear and Related Techniques in Assessment of Irrigation Schedules of Field Crops to Increase Effective Use of Water in Irrigation Projects'', was held in Vienna in February 1992, and excerpts from the presented reports are also included in the Newsletter. In addition, there are brief summaries of the Technical Cooperation Projects in the Middle East and Europe region
Robles-Mendoza, Cecilia; Zúñiga-Lagunes, Sebastian R; Ponce de León-Hill, Claudia A; Hernández-Soto, Jesús; Vanegas-Pérez, Cecilia
2011-10-01
The axolotl Ambystoma mexicanum is a neotenic salamander considered a good biological model due to its ability to regenerate limbs, tail, brain and heart cells. Nevertheless, severe reduction of A. mexicanum wild populations in the lacustrine area of Xochimilco, the natural habitat of the axolotl, could be related to several environmental pressures as the presence of organophosphate pesticides (OPPs), intensively applied in agricultural activities in Xochimilco. Thus the aim of this study was to evaluate the effect of environmentally realistic chlorpyrifos (CPF) concentrations, a OPP commonly used in this zone, on esterases activity (acetylcholinesterase and carboxylesterase) and bioconcentration of CPF and to relate them with the motor activity of A. mexicanum juveniles. Axolotls were exposed 48 h to 0.05 and 0.1mg CPF/L, and the responses were evaluated at the end of the CPF exposure. Results suggest that CPF is bioconcentrated into axolotls and that the CPF internal concentrations are related with the observed inhibition activity of AChE (>50%) and CbE (≈ 50%). CPF concentration responsible of the inhibition of the 50% of AChE activity (IC50) was estimated in 0.04 mg CPF/L; however IC50 for CbE activity was not possible to calculate since inhibition levels were lower than 50%, results that suggest a higher resistance of CbE enzymatic activity to CPF. However, motor activity was a more sensitive endpoint to CPF poisoning since time that axolotls spent active and walking, frequency and speed of swimming, frequency of prey attack were reduced >90% of control groups. The motor activity alterations in the axolotl could be related with the registered esterases inhibition. Thus important alterations on axolotls were identified even at short time and low concentrations of CPF exposure. Also, it was possible to link biochemical responses as esterases activity with higher levels of biological organization as behavior. This study provides tools for the regulation of the
DEFF Research Database (Denmark)
Thygesen, Mathias; Rasmussen, Mikkel Mylius; Madsen, Jesper Guldsmed
2017-01-01
The Mexican axolotl (Ambystoma mexicanum) is an important model species in regenerative biology. Traditionally, axolotls are anesthetized using benzocaine or MS-222, both of which act to inhibit voltage gated sodium channels thereby preventing action potential propagation. In some neurophysiologi......The Mexican axolotl (Ambystoma mexicanum) is an important model species in regenerative biology. Traditionally, axolotls are anesthetized using benzocaine or MS-222, both of which act to inhibit voltage gated sodium channels thereby preventing action potential propagation. In some...... neurophysiological experiments this is not desirable; therefore we tested propofol as an alternative anesthetic in the axolotl. We evaluated benzocaine, MS-222, and propofol's cardiovascular effects, effects on action potential propagation in the spinal cord, and gross limb regenerative effects. We found...
Food irradiation newsletter. V.18, no.1
International Nuclear Information System (INIS)
1994-04-01
This newsletter contains a report on the 10th Annual Meeting of the International Consultative Group on Food Irradiations, summaries of the Second Research Co-ordination Meetings(RCMs) and Final RCM of the Asian Regional Co-operative Project on Food Irradiation with Emphasis on Process Control and Applications(RPFI-Pase III), the resolutions and considerations of food irradiation by the IAEA Board and summaries of the Regional Project for Research, Developing and Training on the Application of Nuclear Techniques to Food Preservation in the Near East. Reviews and order information for new publications and a listing of future meetings and workshops are located in the back of this newsletter
Evidence for balancing selection at the DAB locus in the axolotl, Ambystoma mexicanum.
Richman, A D; Herrera, G; Reynoso, V H; Méndez, G; Zambrano, L
2007-12-01
The axolotl (Ambystoma mexicanum) has been characterized as immunodeficient, and the absence of major histocompatibility complex (MHC) class II polymorphism has been cited as a possible explanation. Here we present evidence for considerable allelic polymorphism at the MHC class II DAB locus for a sample of wild-caught axolotls. Evidence that these sequences are the product of balancing selection for disease resistance is discussed.
Injection of an antibody against a p21 c-Ha-ras protein inhibits cleavage in axolotl eggs.
Baltus, E; Hanocq-Quertier, J; Hanocq, F; Brachet, J
1988-01-01
The presence of a ras protein was demonstrated in cleaving axolotl eggs by selective immunoprecipitation with a polyclonal antibody against a peptide encoded by the c-Ha-ras oncogene, cellular homolog of the v-Ha-ras oncogene of Harvey rat sarcoma virus. Injection of this antibody into axolotl oocytes subjected to progesterone treatment does not prevent meiotic maturation. Injection of the same antibody into a blastomere of axolotl eggs at the 2- or 4-cell stage causes cleavage arrest in the ...
Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
Directory of Open Access Journals (Sweden)
Sabina Wischin
2017-04-01
Full Text Available Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017 [1]. The data revealed that active β-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation.
Gallium nitrate: effects on cartilage during limb regeneration in the axolotl, Ambystoma mexicanum.
Tassava, Roy A; Mendenhall, Luciara; Apseloff, Glen; Gerber, Nicholas
2002-09-01
Gallium nitrate, a drug shown to have efficacy in Paget's disease of bone, hypercalcemia of malignancy, and a variety of experimental autoimmune diseases, also inhibits the growth of some types of cancer. We examined dose and timing of administration of gallium nitrate on limb regeneration in the Mexican axolotl, Ambystoma mexicanum. Administered by intraperitoneal injection, gallium nitrate inhibited limb regeneration in a dose-dependent manner. Gallium nitrate initially suppressed epithelial wound healing and subsequently distorted both anterior-posterior and proximo-distal chondrogenic patterns. Gallium nitrate given at three days after amputation severely inhibited regeneration at high doses (6.25 mg/axolotl) and altered the normal patterning of the regenerates at low doses (3.75 mg/axolotl). Administration of 6.25 mg of gallium nitrate at four or 14 days prior to amputation also inhibited regeneration. In amputated limbs of gallium-treated axolotls, the chondrocytes were lost from inside the radius/ulna. Limbs that regenerated after gallium treatment was terminated showed blastema formation preferentially over the ulna. New cartilage of the regenerate often attached to the sides of the existing radius/ulna proximally into the stump and less so to the distal cut ends. J. Exp. Zool. 293:384-394, 2002. Copyright 2002 Wiley-Liss, Inc.
André, Sébastien; Kerfourn, Fabienne; Affaticati, Pierre; Guerci, Aline; Ravassard, Philippe; Fellah, Julien S
2007-06-01
Gammadelta T cells localize at mammalian epithelial surfaces to exert both protective and regulatory roles in response to infections. We have previously characterized the Mexican axolotl (Ambystoma mexicanum) T cell receptor delta (TRD) chain. In this study, TRD repertoires in spleen, liver, intestine and skin from larvae, pre-adult and adult axolotls were examined and compared to the thymic TRD repertoire. A TRDV transcript without N/D diversity, TRDV1S1-TRDJ1, dominates the TRD repertoires until sexual maturation. In adult tissues, this canonical transcript is replaced by another dominant TRDV1S1-TRDJ1 transcript. In the thymus, these two transcripts are detected early in development. Our results suggest that gammadelta T cells that express the canonical TRDV1S1-TRDJ1 transcript emerge from the thymus and colonize the peripheral tissues, where they are selectively expanded by recurrent ligands. This particular situation is probably related to the neotenic state and the slow development of the axolotl. In thymectomized axolotls, TRD repertoires appear different from those of normal axolotls, suggesting that extrathymic gammadelta T cell differentiation could occur. Gene expression analysis showed the importance of the gut in T cell development.
Soils newsletter. V. 22, no. 1
International Nuclear Information System (INIS)
1999-06-01
This issue of the Newsletter highlights a number of coordinated research project meetings including isotope techniques in studies on management of organic matter and nutrient turnover, use of irradiated sewage sludge ti increase soil fertility, assessment of soil erosion. Status of existing co-ordinated and technical co-operation research projects is also summarized
Fei, Ji-Feng; Schuez, Maritta; Knapp, Dunja; Taniguchi, Yuka; Drechsel, David N; Tanaka, Elly M
2017-11-21
Salamanders exhibit extensive regenerative capacities and serve as a unique model in regeneration research. However, due to the lack of targeted gene knockin approaches, it has been difficult to label and manipulate some of the cell populations that are crucial for understanding the mechanisms underlying regeneration. Here we have established highly efficient gene knockin approaches in the axolotl ( Ambystoma mexicanum ) based on the CRISPR/Cas9 technology. Using a homology-independent method, we successfully inserted both the Cherry reporter gene and a larger membrane-tagged Cherry-ER T2 -Cre-ER T2 (∼5-kb) cassette into axolotl Sox2 and Pax7 genomic loci. Depending on the size of the DNA fragments for integration, 5-15% of the F0 transgenic axolotl are positive for the transgene. Using these techniques, we have labeled and traced the PAX7-positive satellite cells as a major source contributing to myogenesis during axolotl limb regeneration. Our work brings a key genetic tool to molecular and cellular studies of axolotl regeneration.
Transgenesis in axolotl (Ambystoma mexicanum).
Khattak, Shahryar; Tanaka, Elly M
2015-01-01
Transgenic animals have been indispensable in elucidating and deciphering mechanisms underlying various biological phenomena. In regeneration, transgenic animals expressing fluorescent protein genes have been crucial for identifying the source cells for regeneration and the mechanism of blastema formation. Animals are usually generated by manipulating their genome using various techniques at/in one cell embryo/fertilized egg stage. Here, we describe the generation of germline transgenic axolotls (Ambystoma mexicanum) using the I-SceI meganuclease and Tol2 transposase.
Directory of Open Access Journals (Sweden)
Kevin W Hall
Full Text Available Pheromones play an important role in modifying vertebrate behavior, especially during courtship and mating. Courtship behavior in urodele amphibians often includes female exposure to secretions from the cloacal gland, as well as other scent glands. The first vertebrate proteinaceous pheromone discovered, the decapeptide sodefrin, is a female attracting pheromone secreted by the cloacal gland of male Cynops pyrrhogaster. Other proteinaceous pheromones in salamanders have been shown to elicit responses from females towards conspecific males. The presence and levels of expression of proteinaceous pheromones have not been identified in the family Ambystomatidae, which includes several important research models. The objective of this research was therefore to identify putative proteinaceous pheromones from male axolotls, Ambystoma mexicanum, as well as their relative expression levels. The results indicate that axolotls possess two different forms of sodefrin precursor-like factor (alpha and beta, as well as a putative ortholog of plethodontid modulating factor. The beta form of sodefrin precursor-like factor was amongst the most highly expressed transcripts within the cloacal gland. The ortholog of plethodontid modulating factor was expressed at a level equivalent to the beta sodefrin precursor-like factor. The results are from a single male axolotl; therefore, we are unable to assess how representative our results may be. Nevertheless, the presence of these highly expressed proteinaceous pheromones suggests that male axolotls use multiple chemical cues to attract female conspecifics. Behavioral assays would indicate whether the putative protein pheromones elicit courtship activity from female axolotls.
Hall, Kevin W; Eisthen, Heather L; Williams, Barry L
2016-01-01
Pheromones play an important role in modifying vertebrate behavior, especially during courtship and mating. Courtship behavior in urodele amphibians often includes female exposure to secretions from the cloacal gland, as well as other scent glands. The first vertebrate proteinaceous pheromone discovered, the decapeptide sodefrin, is a female attracting pheromone secreted by the cloacal gland of male Cynops pyrrhogaster. Other proteinaceous pheromones in salamanders have been shown to elicit responses from females towards conspecific males. The presence and levels of expression of proteinaceous pheromones have not been identified in the family Ambystomatidae, which includes several important research models. The objective of this research was therefore to identify putative proteinaceous pheromones from male axolotls, Ambystoma mexicanum, as well as their relative expression levels. The results indicate that axolotls possess two different forms of sodefrin precursor-like factor (alpha and beta), as well as a putative ortholog of plethodontid modulating factor. The beta form of sodefrin precursor-like factor was amongst the most highly expressed transcripts within the cloacal gland. The ortholog of plethodontid modulating factor was expressed at a level equivalent to the beta sodefrin precursor-like factor. The results are from a single male axolotl; therefore, we are unable to assess how representative our results may be. Nevertheless, the presence of these highly expressed proteinaceous pheromones suggests that male axolotls use multiple chemical cues to attract female conspecifics. Behavioral assays would indicate whether the putative protein pheromones elicit courtship activity from female axolotls.
ITER EDA newsletter. V. 9, no. 9
International Nuclear Information System (INIS)
2000-09-01
This ITER EDA Newsletter contains the following 5 contributions: CSMC and CSIC charging tests successfully completed; The ITER divertor cassette project meeting; Blanket R and D and design task meeting; IAEA technical committee meeting on fusion safety; ITER L-6 large project ''blanket remote handling and maintenance''
Diffusion tensor tractography reveals muscle reconnection during axolotl limb regeneration.
Directory of Open Access Journals (Sweden)
Cheng-Han Wu
Full Text Available Axolotls have amazing ability to regenerate their lost limbs. Our previous works showed that after amputation the remnant muscle ends remained at their original location whilst sending satellite cells into the regenerating parts to develop into early muscle fibers in the late differentiation stage. The parental and the newly formed muscle fibers were not connected until very late stage. The present study used non-invasive diffusion tensor imaging (DTI to monitor weekly axolotl upper arm muscles after amputation of their upper arms. DTI tractography showed that the regenerating muscle fibers became visible at 9-wpa (weeks post amputation, but a gap was observed between the regenerating and parental muscles. The gap was filled at 10-wpa, indicating reconnection of the fibers of both muscles. This was confirmed by histology. The DTI results indicate that 23% of the muscle fibers were reconnected at 10-wpa. In conclusion, DTI can be used to visualize axolotls' skeletal muscles and the results of muscle reconnection were in accordance with our previous findings. This non-invasive technique will allow researchers to identify the timeframe in which muscle fiber reconnection takes place and thus enable the study of the mechanisms underlying this reconnection.
International Nuclear Information System (INIS)
2001-10-01
This ITER CTA newsletter contains results of the ITER toroidal field model coil project presented by ITER EU Home Team (Garching) and an article in commemoration of the late Dr. Charles Maisonnier, one of the former leaders of ITER who made significant contributions to its development
Identification of Conserved and Novel MicroRNAs during Tail Regeneration in the Mexican Axolotl
Directory of Open Access Journals (Sweden)
Micah D. Gearhart
2015-09-01
Full Text Available The Mexican axolotl salamander (Ambystoma mexicanum is one member of a select group of vertebrate animals that have retained the amazing ability to regenerate multiple body parts. In addition to being an important model system for regeneration, the axolotl has also contributed extensively to studies of basic development. While many genes known to play key roles during development have now been implicated in various forms of regeneration, much of the regulatory apparatus controlling the underlying molecular circuitry remains unknown. In recent years, microRNAs have been identified as key regulators of gene expression during development, in many diseases and also, increasingly, in regeneration. Here, we have used deep sequencing combined with qRT-PCR to undertake a comprehensive identification of microRNAs involved in regulating regeneration in the axolotl. Specifically, among the microRNAs that we have found to be expressed in axolotl tissues, we have identified 4564 microRNA families known to be widely conserved among vertebrates, as well as 59,811 reads of putative novel microRNAs. These findings support the hypothesis that microRNAs play key roles in managing the precise spatial and temporal patterns of gene expression that ensures the correct regeneration of missing tissues.
Woodcock, M Ryan; Vaughn-Wolfe, Jennifer; Elias, Alexandra; Kump, D Kevin; Kendall, Katharina Denise; Timoshevskaya, Nataliya; Timoshevskiy, Vladimir; Perry, Dustin W; Smith, Jeramiah J; Spiewak, Jessica E; Parichy, David M; Voss, S Randal
2017-01-31
The molecular genetic toolkit of the Mexican axolotl, a classic model organism, has matured to the point where it is now possible to identify genes for mutant phenotypes. We used a positional cloning-candidate gene approach to identify molecular bases for two historic axolotl pigment phenotypes: white and albino. White (d/d) mutants have defects in pigment cell morphogenesis and differentiation, whereas albino (a/a) mutants lack melanin. We identified in white mutants a transcriptional defect in endothelin 3 (edn3), encoding a peptide factor that promotes pigment cell migration and differentiation in other vertebrates. Transgenic restoration of Edn3 expression rescued the homozygous white mutant phenotype. We mapped the albino locus to tyrosinase (tyr) and identified polymorphisms shared between the albino allele (tyr a ) and tyr alleles in a Minnesota population of tiger salamanders from which the albino trait was introgressed. tyr a has a 142 bp deletion and similar engineered alleles recapitulated the albino phenotype. Finally, we show that historical introgression of tyr a significantly altered genomic composition of the laboratory axolotl, yielding a distinct, hybrid strain of ambystomatid salamander. Our results demonstrate the feasibility of identifying genes for traits in the laboratory Mexican axolotl.
ITER EDA newsletter. V. 5, no. 9
International Nuclear Information System (INIS)
1996-09-01
This issue of the Newsletter on the Engineering Design Activities (EDA) for the ITER project contains an overview of one of the seven large ITER Research and Development Projects identified by the ITER Director, namely the Vacuum Vessel Sector, as well as an account of computer animation created for ITER
Evaluation of the anesthetic effects of MS222 in the adult Mexican axolotl (Ambystoma mexicanum
Directory of Open Access Journals (Sweden)
Zullian C
2016-01-01
Full Text Available Chiara Zullian,1 Aurore Dodelet-Devillers,1 Stéphane Roy,2 Pascal Vachon1 1Département de Biomédecine Vétérinaire, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, 2Département de Stomatologie, Faculté de Médecine Dentaire, Montréal, Québec, Canada Abstract: The Mexican axolotl (Ambystoma mexicanum is a unique research model in several fields of medicine, where surgical and invasive procedures may be required. As yet, little is known about the efficacy of MS222 (tricaine methanesulfonate, which is the most commonly used anesthetic agent in amphibians. The main objectives of this study were to evaluate the anesthetic effects and physiological changes in adult axolotls following a 20-minute immersion bath, containing progressive MS222 concentrations starting at 0.1%. Depth of anesthesia and physiological changes were evaluated every 15 minutes post-MS222 exposure with the following parameters: righting behavior, withdrawal reflex, acetic acid test response, heart rate, and blood oxygen saturation, as well as cloacal and body surface temperatures. A 20-minute exposure in a 0.1% MS222 immersion bath (n=6 animals had no anesthetic effects on adult axolotls after 20 minutes of exposure. With a 0.2% MS222 solution, all axolotls (n=9 were deeply anesthetized at 15 minutes, and 80% were still unresponsive at 30 minutes postexposure. Blood oxygen saturation and heart rate were slightly, but significantly, increased when compared with the baseline value and remained stable up to recovery. There was no significant increase in surface and cloaca temperatures, compared with baseline. With the 0.4% MS222 solution, the duration of anesthesia lasted for 90 minutes to at least 120 minutes (n=3 animals and this concentration was deemed too high. In conclusion, a 20-minute immersion bath with 0.2% MS222 may be used for short procedures (15–30 minutes requiring anesthesia of adult axolotls. Keywords: Ambystoma mexicanum
ITER EDA newsletter. V. 8, no. 7
International Nuclear Information System (INIS)
1999-07-01
This newsletter contains an article concerning the ITER divertor cassette project meeting in Bologna, Italy (May 26-28, 1999), and an emotional outburst, concerning the closure of the ITER site in San Diego, USA
Animal production and health newsletter. No. 32
International Nuclear Information System (INIS)
2000-06-01
Project reviews and research coordination meetings on milk production, rinderpest diagnosis, animal vaccinations, quality assurance in veterinary diagnostic laboratories and evaluation of animal feeds are the major highlights of this issue of the Newsletter
DEFF Research Database (Denmark)
Thygesen, Mathias; Rasmussen, Mikkel Mylius; Madsen, Jesper Guldsmed
2017-01-01
The Mexican axolotl (Ambystoma mexicanum) is an important model species in regenerative biology. Traditionally, axolotls are anesthetized using benzocaine or MS-222, both of which act to inhibit voltage gated sodium channels thereby preventing action potential propagation. In some...... neurophysiological experiments this is not desirable; therefore we tested propofol as an alternative anesthetic in the axolotl. We evaluated benzocaine, MS-222, and propofol's cardiovascular effects, effects on action potential propagation in the spinal cord, and gross limb regenerative effects. We found...... that propofol is applicable as a general anesthetic in the axolotl allowing for neurophysiological experiments and yielding a stable anesthesia with significantly less cardiovascular effect than both benzocaine and MS-222. Additionally, propofol did not affect gross limb regeneration. In conclusion we suggest...
Robles-Mendoza, C; García-Basilio, C; Cram-Heydrich, S; Hernández-Quiroz, M; Vanegas-Pérez, C
2009-02-01
Ambystoma mexicanum is an endemic salamander of Xochimilco, a wetland of the basin of Mexico valley. Nowadays, axolotl populations are decreasing due environmental stressors. Particularly, studies about organophosphorus pesticides (OPPs; i.e. chlorpyrifos and malathion) toxicity are of great importance due to their intensive use in agricultural activities in Xochimilco. Thus, the aim of this study was to evaluate under controlled conditions the toxicity of chlorpyrifos (CPF) and malathion (MLT) on embryos and larvae (stage 44 and 54) of A. mexicanum. Embryos and larvae were exposure 96h from 0.5 to 3mg CPFL(-1) and from 10 to 30mg MLTL(-1) in independent tests. Embryos at the end of this period were maintained 9d without pesticide in order to identify possible recuperation. Differences obtained in mortality, hatching success, development, morphological abnormalities, behaviour and activity, suggest that toxicity of CPF and MLT differs in embryos and larval stages. Embryos were less sensitive to OPPs acute exposure than axolotl larvae; additionally, toxicity of CPF in larval stages was greater than MLT. On the other hand, data obtained in axolotl embryos during the period of recuperation to CPF in particular as delay and inhibition of development, malformations and success of hatching, indicated that these responses turned out more sensitive than mortality. This study allowed to identify the toxicological potential of OPPs on early developmental stages of A. mexicanum and it is a valuable contribution for the future management of the axolotl wild population.
Insect Pest Control Newsletter, No. 73, July 2009
International Nuclear Information System (INIS)
2009-07-01
This issue of the Newsletter reports on status of technical cooperation field projects, coordinated research projects and research coordination meetings, developments at the Entomology Unit Seibersdorf, training courses offered on insect pest control as well as news items on other activities of the Insect Pest Control Section
Insect Pest Control Newsletter, No. 73, July 2009
Energy Technology Data Exchange (ETDEWEB)
NONE
2009-07-15
This issue of the Newsletter reports on status of technical cooperation field projects, coordinated research projects and research coordination meetings, developments at the Entomology Unit Seibersdorf, training courses offered on insect pest control as well as news items on other activities of the Insect Pest Control Section.
Expression of Msx genes in regenerating and developing limbs of axolotl.
Koshiba, K; Kuroiwa, A; Yamamoto, H; Tamura, K; Ide, H
1998-12-15
Msx genes, homeobox-containing genes, have been isolated as homologues of the Drosophila msh gene and are thought to play important roles in the development of chick or mouse limb buds. We isolated two Msx genes, Msx1 and Msx2, from regenerating blastemas of axolotl limbs and examined their expression patterns using Northern blot and whole mount in situ hybridization during regeneration and development. Northern blot analysis revealed that the expression level of both Msx genes increased during limb regeneration. The Msx2 expression level increased in the blastema at the early bud stage, and Msx1 expression level increased at the late bud stage. Whole mount in situ hybridization revealed that Msx2 was expressed in the distal mesenchyme and Msx1 in the entire mesenchyme of the blastema at the late bud stage. In the developing limb bud, Msx1 was expressed in the entire mesenchyme, while Msx2 was expressed in the distal and peripheral mesenchyme. The expression patterns of Msx genes in the blastemas and limb buds of the axolotl were different from those reported for chick or mouse limb buds. These expression patterns of axolotl Msx genes are discussed in relation to the blastema or limb bud morphology and their possible roles in limb patterning.
Zhang, C; Pietras, K M; Sferrazza, G F; Jia, P; Athauda, G; Rueda-de-Leon, E; Rveda-de-Leon, E; Maier, J A; Dube, D K; Lemanski, S L; Lemanski, L F
2007-01-01
The Mexican axolotl, Ambystoma mexicanum, is an excellent animal model for studying heart development because it carries a naturally occurring recessive genetic mutation, designated gene c, for cardiac nonfunction. The double recessive mutants (c/c) fail to form organized myofibrils in the cardiac myoblasts resulting in hearts that fail to beat. Tropomyosin expression patterns have been studied in detail and show dramatically decreased expression in the hearts of homozygous mutant embryos. Because of the direct interaction between tropomyosin and troponin T (TnT), and the crucial functions of TnT in the regulation of striated muscle contraction, we have expanded our studies on this animal model to characterize the expression of the TnT gene in cardiac muscle throughout normal axolotl development as well as in mutant axolotls. In addition, we have succeeded in cloning the full-length cardiac troponin T (cTnT) cDNA from axolotl hearts. Confocal microscopy has shown a substantial, but reduced, expression of TnT protein in the mutant hearts when compared to normal during embryonic development. 2006 Wiley-Liss, Inc.
International Nuclear Information System (INIS)
2002-06-01
This ITER CTA newsletter contains information about the Fourth Negotiations Meeting on the Joint Implementation of ITER held in Cadarache, France on 4-6 June 2002 and about the meeting of the ITER CTA Project Board which took place on the occasion of the N4 Meeting at Cadarache on 3-4 June 2002
International Nuclear Information System (INIS)
2001-01-01
This ITER CTA newsletter comprises reports on ITER co-ordinated technical activities, information about the Meeting of the ITER CTA project board which took place in Vienna on 16 July 2001, and the Meeting of the expert group on MHD, disruptions and plasma control which was held on 25-26 June 2001 in Funchal, Madeira
Directory of Open Access Journals (Sweden)
Lemanski Sharon L
2009-09-01
Full Text Available Abstract The Mexican axolotl, Ambystoma mexicanum, carries the naturally-occurring recessive mutant gene 'c' that results in a failure of homozygous (c/c embryos to form hearts that beat because of an absence of organized myofibrils. Our previous studies have shown that a noncoding RNA, Myofibril-Inducing RNA (MIR, is capable of promoting myofibrillogenesis and heart beating in the mutant (c/c axolotls. The present study demonstrates that the MIR gene is essential for tropomyosin (TM expression in axolotl hearts during development. Gene expression studies show that mRNA expression of various tropomyosin isoforms in untreated mutant hearts and in normal hearts knocked down with double-stranded MIR (dsMIR are similar to untreated normal. However, at the protein level, selected tropomyosin isoforms are significantly reduced in mutant and dsMIR treated normal hearts. These results suggest that MIR is involved in controlling the translation or post-translation of various TM isoforms and subsequently of regulating cardiac contractility.
Spent Fuel Management Newsletter. No. 1
International Nuclear Information System (INIS)
1990-03-01
This Newsletter has been prepared in accordance with the recommendations of the International Regular Advisory Group on Spent Fuel Management and the Agency's programme (GC XXXII/837, Table 76, item 14). The main purpose of the Newsletter is to provide Member States with new information about the state-of-the-art in one of the most important parts of the nuclear fuel cycle - Spent Fuel Management. The contents of this publication consists of two parts: (1) IAEA Secretariat contribution -work and programme of the Nuclear Materials and Fuel Cycle Technology Section of the Division of Nuclear Fuel Cycle and Waste Management, recent and planned meetings and publications, Technical Co-operation projects, Co-ordinated Research programmes, etc. (2) Country reports - national programmes on spent fuel management: current and planned storage and reprocessing capacities, spent fuel arisings, safety, transportation, storage, treatment of spent fuel, some aspects of uranium and plutonium recycling, etc. The IAEA expects to publish the Newsletter once every two years between the publications of the Regular Advisory Group on Spent Fuel Management. Figs and tabs
Nuclear Data Newsletter, No. 54, November 2012
International Nuclear Information System (INIS)
2012-11-01
This issue of Nuclear Data Newsletter features Message from the Section Head; Nuclear Data Section IT resources; Computer codes and data libraries - News; NDS meeting reports; Selected charts, reports and documents; Coordinated research projects; Staff items and Forthcoming event.
ITER EDA newsletter. V. 5, no. 8
International Nuclear Information System (INIS)
1996-08-01
This issue of the Newsletter on the Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on the divertor remote handling development (and of a summer party at the ITER Joint Work Site in Garching, Germany)
ITER EDA newsletter. V. 5, no. 8
Energy Technology Data Exchange (ETDEWEB)
NONE
1996-08-01
This issue of the Newsletter on the Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on the divertor remote handling development (and of a summer party at the ITER Joint Work Site in Garching, Germany).
International Nuclear Information System (INIS)
2002-04-01
This issue of ITER CTA newsletter contains information about the meeting of the ITER CTA project board, which took place in Moscow, Russian Federation on 22 April 2002 on the occasion of the Third Negotiators Meeting (N3), and about the meeting 'EU divertor celebration day' organized on 16 January 2002 at Plansee AG, Reutte, Austria
ITER EDA newsletter. V. 7, no. 6
International Nuclear Information System (INIS)
1998-06-01
This newsletter contains the articles: 'ITER representation at the 11th Pacific Basin Nuclear Conference', 'Summary of discussion points and further deliberations in the special committee on the ITER project in the Atomic Energy Commission', and 'ITER radio frequency systems'
ITER ITA newsletter. No. 21, April 2005
International Nuclear Information System (INIS)
2005-05-01
This issue of ITER ITA (ITER transitional Arrangements) newsletter contains concise information about Russian federation Participant Team's activity in the area of preparation for ITER construction and information about International Fusion materials irradiation Facility(IRMIF) project and prospects for implementation
Animal production and health newsletter. No. 30
International Nuclear Information System (INIS)
1999-06-01
This issue of the Newsletter highlights forthcoming events including regional workshops, research coordination meetings and training courses on use isotope application in the diagnosis of animal diseases. Status of existing co-ordinated and technical co-operation research projects is also summarized
Regulation of antibody synthesis in the X-irradiated Mexican axolotl
International Nuclear Information System (INIS)
Charlemagne, J.
1981-01-01
The effects of X-irradiation were studied on the Mexican axolotl antibody synthesis. To reduce the anti-horse red blood cell (HRBC) antibody titers, 150 rd and smaller doses are ineffective, 200-450 rd are increasingly effective, and 700 rd are maximally effective (and lethal). A significant enhancement of the anti-HRBC titers was observed in low doses (50-150 rd X-irradiated animals). This enhancement was also observed when a low X-ray dose was applied only on the thymic areas. In whole body, but thymus area-shielded, 100 rd X-irradiated animals, the anti-HRBC titers were similar to those of the nonirradiated, HRBC-immunized control group. To explain these phenomena, it is suggested that a radiosensitive, adult thymectomy-sensitive and hydrocortisone-sensitive suppressor T cell subpopulation regulates the antibody synthesis in the axolotl. (orig.) [de
Regulation of antibody synthesis in the X-irradiated Mexican axolotl
Energy Technology Data Exchange (ETDEWEB)
Charlemagne, J.
1981-09-01
The effects of X-irradiation were studied on the Mexican axolotl antibody synthesis. To reduce the anti-horse red blood cell (HRBC) antibody titers, 150 rd and smaller doses are ineffective, 200-450 rd are increasingly effective, and 700 rd are maximally effective (and lethal). A significant enhancement of the anti-HRBC titers was observed in low doses (50-150 rd X-irradiated animals). This enhancement was also observed when a low X-ray dose was applied only on the thymic areas. In whole body, but thymus area-shielded, 100 rd X-irradiated animals, the anti-HRBC titers were similar to those of the nonirradiated, HRBC-immunized control group. To explain these phenomena, it is suggested that a radiosensitive, adult thymectomy-sensitive and hydrocortisone-sensitive suppressor T cell subpopulation regulates the antibody synthesis in the axolotl.
ITER EDA Newsletter. Vol. 1, No. 1
International Nuclear Information System (INIS)
1992-11-01
After the ITER Engineering Design Activities (EDA) Agreement and Protocol 1 had been signed by the four ITER parties on July 21, 1992 and had entered into force, the ITER Council suggested at its first meeting (Vienna, September 10-11, 1992) that the publication of the ITER Newsletter be continued during the EDA with assistance of the International Atomic Energy Agency. This suggestion was supported by the Agency and subsequently the ITER office in Vienna assumed its responsibilities for planning and executing activities related to the publication of the Newsletter. The ITER EDA Newsletter is planned to be a monthly publication aimed at disseminating broad information and understanding, including the description of the personal and institutional involvements in the ITER project in addition to technical facts about it. The responsibility for the Newsletter rests with the ITER council. In this first issue the signing of the ITER EDA Activities and Protocol 1 is reported. The EDA organizational structure is described. This issue also reports on the first ITER EDA council meeting, the opening of the ITER EDA NAKA Co-Centre, the first meeting of the ITER Technical Advisory Committee, activities of special working groups, an ITER Technical Meeting, as well as ''News in Brief'' and ''Coming Events''
TASCC newsletter volume 8 no. 5
International Nuclear Information System (INIS)
Thomson, L.
1994-05-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this May issue of TASCC is an update of the facility, a visit by the Nuclear Physics Technical Review Committee, sizing of meteors, Deep River Science Academy on TASCC projects and a listing of May's experiments. 2 figs
Animal production and health newsletter. No. 40
International Nuclear Information System (INIS)
2004-06-01
This issue of the Newsletter highlights the activities of the Animal Production and Health Section and the Sub-programme. Apart from the regular Coordinated Research Project (CRP) activities and the customary technical support given to national and regional Technical Cooperation (TC) projects, the personnel were involved in the technical evaluation of applications for new TC projects by Member States for the 2005/2006 biennial project cycle. The Section also was also occupied with preparing the IAEA's 2006/2007 Work and Budget Programme
The CERN & Society programme launches its newsletter
Matteo Castoldi
2016-01-01
The newsletter will be issued quarterly. Sign up to remain informed about the latest initiatives of the CERN & Society programme! The CERN & Society programme encompasses projects in the areas of education and outreach, innovation and knowledge exchange, and culture and creativity that spread the CERN spirit of scientific curiosity for the inspiration and benefit of society. The programme is funded primarily by the CERN & Society Foundation, a charitable foundation established by CERN and supported by individuals, trusts, organisations and commercial companies. The projects are inspired or enabled by CERN but lie outside of the Laboratory’s specific research mandate. We especially want to help young talent from around the world to flourish in the future. The programme is now launching its newsletter, which will be issued quarterly. Everybody who wants to be informed about CERN & Society’s activities, stay up-to-date with its latest in...
International Nuclear Information System (INIS)
2001-12-01
This ITER CTA Newsletter contains information about the organization of the ITER Co-ordinated Technical Activities (CTA) International Team as the follow-up of the ITER CTA project board meeting in Toronto on 7 November 2001. It also includes a summary on the start of the international tokamak physics activity by Dr. D. Campbell, Chair of the ITPA Co-ordinating Committee
Mousley, Angela; Polese, Gianluca; Marks, Nikki J.; Eisthen, Heather L.
2007-01-01
The vertebrate brain actively regulates incoming sensory information, effectively filtering input and focusing attention toward environmental stimuli that are most relevant to the animal's behavioral context or physiological state. Such centrifugal modulation has been shown to play an important role in processing in the retina and cochlea, but has received relatively little attention in olfaction. The terminal nerve, a cranial nerve that extends underneath the lamina propria surrounding the olfactory epithelium, displays anatomical and neurochemical characteristics that suggest that it modulates activity in the olfactory epithelium. Using immunocytochemical techniques, we demonstrate that neuropeptide Y (NPY) is abundantly present in the terminal nerve in the axolotl (Ambystoma mexicanum), an aquatic salamander. Because NPY plays an important role in regulating appetite and hunger in many vertebrates, we investigated the possibility that NPY modulates activity in the olfactory epithelium in relation to the animal's hunger level. We therefore characterized the full length NPY gene from axolotls to enable synthesis of authentic axolotl NPY for use in electrophysiological experiments. We find that axolotl NPY modulates olfactory epithelial responses evoked by L-glutamic acid, a food-related odorant, but only in hungry animals. Similarly, whole-cell patch-clamp recordings demonstrate that bath application of axolotl NPY enhances the magnitude of a tetrodotoxin-sensitive inward current, but only in hungry animals. These results suggest that expression or activity of NPY receptors in the olfactory epithelium may change with hunger level, and that terminal nerve-derived peptides modulate activity in the olfactory epithelium in response to an animal's changing behavioral and physiological circumstances. PMID:16855098
Mousley, Angela; Polese, Gianluca; Marks, Nikki J; Eisthen, Heather L
2006-07-19
The vertebrate brain actively regulates incoming sensory information, effectively filtering input and focusing attention toward environmental stimuli that are most relevant to the animal's behavioral context or physiological state. Such centrifugal modulation has been shown to play an important role in processing in the retina and cochlea, but has received relatively little attention in olfaction. The terminal nerve, a cranial nerve that extends underneath the lamina propria surrounding the olfactory epithelium, displays anatomical and neurochemical characteristics that suggest that it modulates activity in the olfactory epithelium. Using immunocytochemical techniques, we demonstrate that neuropeptide Y (NPY) is abundantly present in the terminal nerve in the axolotl (Ambystoma mexicanum), an aquatic salamander. Because NPY plays an important role in regulating appetite and hunger in many vertebrates, we investigated the possibility that NPY modulates activity in the olfactory epithelium in relation to the animal's hunger level. We therefore characterized the full-length NPY gene from axolotls to enable synthesis of authentic axolotl NPY for use in electrophysiological experiments. We find that axolotl NPY modulates olfactory epithelial responses evoked by l-glutamic acid, a food-related odorant, but only in hungry animals. Similarly, whole-cell patch-clamp recordings demonstrate that bath application of axolotl NPY enhances the magnitude of a tetrodotoxin-sensitive inward current, but only in hungry animals. These results suggest that expression or activity of NPY receptors in the olfactory epithelium may change with hunger level, and that terminal nerve-derived peptides modulate activity in the olfactory epithelium in response to an animal's changing behavioral and physiological circumstances.
TASCC newsletter volume 8 no. 5
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1994-05-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this May issue of TASCC is an update of the facility, a visit by the Nuclear Physics Technical Review Committee, sizing of meteors, Deep River Science Academy on TASCC projects and a listing of May`s experiments. 2 figs.
Novel axolotl cardiac function analysis method using magnetic resonance imaging
Sanches, Pedro Gomes; Op 't Veld, Roel C.; de Graaf, Wolter; Strijkers, Gustav J.; Grüll, Holger
2017-01-01
The salamander axolotl is capable of complete regeneration of amputated heart tissue. However, non-invasive imaging tools for assessing its cardiac function were so far not employed. In this study, cardiac magnetic resonance imaging is introduced as a non-invasive technique to image heart function
Novel axolotl cardiac function analysis method using magnetic resonance imaging
Sanches, P.G.; Op ‘t Veld, R.C.; de Graaf, W.; Strijkers, G.J.; Grüll, H.
2017-01-01
The salamander axolotl is capable of complete regeneration of amputated heart tissue. However, non-invasive imaging tools for assessing its cardiac function were so far not employed. In this study, cardiac magnetic resonance imaging is introduced as a noninvasive technique to image heart function of
Nuclear data newsletter. No. 36
International Nuclear Information System (INIS)
2003-09-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres
Nuclear data newsletter. No. 39
International Nuclear Information System (INIS)
2005-05-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres
Nuclear data newsletter. No. 37
International Nuclear Information System (INIS)
2004-04-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres
Directory of Open Access Journals (Sweden)
Ron Stewart
Full Text Available The salamander has the remarkable ability to regenerate its limb after amputation. Cells at the site of amputation form a blastema and then proliferate and differentiate to regrow the limb. To better understand this process, we performed deep RNA sequencing of the blastema over a time course in the axolotl, a species whose genome has not been sequenced. Using a novel comparative approach to analyzing RNA-seq data, we characterized the transcriptional dynamics of the regenerating axolotl limb with respect to the human gene set. This approach involved de novo assembly of axolotl transcripts, RNA-seq transcript quantification without a reference genome, and transformation of abundances from axolotl contigs to human genes. We found a prominent burst in oncogene expression during the first day and blastemal/limb bud genes peaking at 7 to 14 days. In addition, we found that limb patterning genes, SALL genes, and genes involved in angiogenesis, wound healing, defense/immunity, and bone development are enriched during blastema formation and development. Finally, we identified a category of genes with no prior literature support for limb regeneration that are candidates for further evaluation based on their expression pattern during the regenerative process.
Neuregulin-1 signaling is essential for nerve-dependent axolotl limb regeneration.
Farkas, Johanna E; Freitas, Polina D; Bryant, Donald M; Whited, Jessica L; Monaghan, James R
2016-08-01
The Mexican axolotl (Ambystoma mexicanum) is capable of fully regenerating amputated limbs, but denervation of the limb inhibits the formation of the post-injury proliferative mass called the blastema. The molecular basis behind this phenomenon remains poorly understood, but previous studies have suggested that nerves support regeneration via the secretion of essential growth-promoting factors. An essential nerve-derived factor must be found in the blastema, capable of rescuing regeneration in denervated limbs, and its inhibition must prevent regeneration. Here, we show that the neuronally secreted protein Neuregulin-1 (NRG1) fulfills all these criteria in the axolotl. Immunohistochemistry and in situ hybridization of NRG1 and its active receptor ErbB2 revealed that they are expressed in regenerating blastemas but lost upon denervation. NRG1 was localized to the wound epithelium prior to blastema formation and was later strongly expressed in proliferating blastemal cells. Supplementation by implantation of NRG1-soaked beads rescued regeneration to digits in denervated limbs, and pharmacological inhibition of NRG1 signaling reduced cell proliferation, blocked blastema formation and induced aberrant collagen deposition in fully innervated limbs. Taken together, our results show that nerve-dependent NRG1/ErbB2 signaling promotes blastemal proliferation in the regenerating limb and may play an essential role in blastema formation, thus providing insight into the longstanding question of why nerves are required for axolotl limb regeneration. © 2016. Published by The Company of Biologists Ltd.
ITER EDA Newsletter. V. 6, no. 5
International Nuclear Information System (INIS)
1997-05-01
This issue of the newsletter on Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on Second International Industries' Liaison meeting which was held in Tokyo on 2-4 April 1997 (by Y. Kaneki, JAIF, Japan); an overview report on the Blanket project (by A. Cardella, I.Ioki (ITER Central Team), W. Daenner (EU Home Team)); and a progress report on microwave reflectometry (by J. Sanchez, Madrid, Spain)
ITER EDA Newsletter. V. 6, no. 5
Energy Technology Data Exchange (ETDEWEB)
NONE
1997-05-01
This issue of the newsletter on Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on Second International Industries` Liaison meeting which was held in Tokyo on 2-4 April 1997 (by Y. Kaneki, JAIF, Japan); an overview report on the Blanket project (by A. Cardella, I.Ioki (ITER Central Team), W. Daenner (EU Home Team)); and a progress report on microwave reflectometry (by J. Sanchez, Madrid, Spain).
Hanner, R H; Ryan, G B
1980-01-01
Renal juxtaglomerular regions were examined in the axolotl (Ambystoma mexicanum and toad (Bufo marinus). Prominent granulated peripolar epithelial cells were found surrounding the origin of the glomerular tuft in the axolotl. These cells resembled the peripolar cells recently discovered in mammalian species. They contained multiple electron-dense cytoplasmic granules, some of which showed a paracrystalline substructure and signs of exocytoxic activity. Such cells were difficult to find and smaller in the toad. In contrast, granulated juxtaglomerular arteriolar myoephithelial cells were much more readily found and larger in the toad than in the axolotl. No consistent differences were noted in juxtaglomerular cells or their granules in response to changes in environmental chloride concentration. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 PMID:7410189
Nuclear data newsletter. No. 38
Energy Technology Data Exchange (ETDEWEB)
NONE
2004-09-15
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning web and database services, nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres.
Nuclear data newsletter. No. 38
International Nuclear Information System (INIS)
2004-09-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning web and database services, nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres
Plant breeding and genetics newsletter. No. 4
International Nuclear Information System (INIS)
1999-12-01
The Newsletter reports development of new Coordinated Research Projects (CRPs) and on efficient implementation of Technical Coperaton Projects related to regional activities. Following the organization of the CRP on 'Molecular characterization of mutated genes controlling important traits for seed crop improvement' the CRP on 'Mutational analysis of root characters in annual food plants related to plant performance' was also established with the participation of 21 institutes. It also presents recent training activities and meetings undertaken
International Nuclear Information System (INIS)
2003-09-01
This third issue of the Newsletter is characterised by the key words 'demonstration' and 'scientific maturity' as opposed to the 'winds of change' in the second issue. Nuclear desalination studies in the INDAG member countries have moved from the generic studies to site-specific (e.g. the CRP on economics) studies and now to demonstration projects. The demonstration project at KALPAKKAM (INDIA) is now going on at full speed. That of KANNUP (PAKISTAN) will begin soon. A Similar project for the MEDITERRANEAN region is currently under consideration in France. Similarly, in its latest call for proposals for its 6th Framework programme, the European Commission has launched an ambitious programme of research and technological development in the field of Management of scarce water resources and mitigation technologies. This programme specifically calls for research in desalination
Cross-Cultural Psychology Newsletter. Volume 7, Number 2.
Dawson, John, Ed.
The Cross-Cultural Psychology Newsletter, an official publication of the International Association for Cross-Cultural Psychology, reports on recent publications and research in cross-cultural psychology. Notes on international conferences in the field are followed by annotations of new publications. In addition, recent research projects are…
Animal production and health newsletter. No. 33
International Nuclear Information System (INIS)
2000-12-01
A full report on the final research coordination meeting on the long running Coordinated Research Project supporting rinderpest eradication is contained in this Newsletter. It is reported that all the national rinderpest vaccination campaigns have been terminated and except for a very few isolated areas where vaccination continues, the effort is now on disease surveillance to demonstrate freedom from rinderpest. Other research coordination meetings on animal diseases and productivity as well as new projects are highlighted in this issue
Animal production and health newsletter. No. 33
Energy Technology Data Exchange (ETDEWEB)
NONE
2000-12-01
A full report on the final research coordination meeting on the long running Coordinated Research Project supporting rinderpest eradication is contained in this Newsletter. It is reported that all the national rinderpest vaccination campaigns have been terminated and except for a very few isolated areas where vaccination continues, the effort is now on disease surveillance to demonstrate freedom from rinderpest. Other research coordination meetings on animal diseases and productivity as well as new projects are highlighted in this issue.
Regeneration of limb joints in the axolotl (Ambystoma mexicanum).
Lee, Jangwoo; Gardiner, David M
2012-01-01
In spite of numerous investigations of regenerating salamander limbs, little attention has been paid to the details of how joints are reformed. An understanding of the process and mechanisms of joint regeneration in this model system for tetrapod limb regeneration would provide insights into developing novel therapies for inducing joint regeneration in humans. To this end, we have used the axolotl (Mexican Salamander) model of limb regeneration to describe the morphology and the expression patterns of marker genes during joint regeneration in response to limb amputation. These data are consistent with the hypothesis that the mechanisms of joint formation whether it be development or regeneration are conserved. We also have determined that defects in the epiphyseal region of both forelimbs and hind limbs in the axolotl are regenerated only when the defect is small. As is the case with defects in the diaphysis, there is a critical size above which the endogenous regenerative response is not sufficient to regenerate the joint. This non-regenerative response in an animal that has the ability to regenerate perfectly provides the opportunity to screen for the signaling pathways to induce regeneration of articular cartilage and joints.
Regeneration of limb joints in the axolotl (Ambystoma mexicanum.
Directory of Open Access Journals (Sweden)
Jangwoo Lee
Full Text Available In spite of numerous investigations of regenerating salamander limbs, little attention has been paid to the details of how joints are reformed. An understanding of the process and mechanisms of joint regeneration in this model system for tetrapod limb regeneration would provide insights into developing novel therapies for inducing joint regeneration in humans. To this end, we have used the axolotl (Mexican Salamander model of limb regeneration to describe the morphology and the expression patterns of marker genes during joint regeneration in response to limb amputation. These data are consistent with the hypothesis that the mechanisms of joint formation whether it be development or regeneration are conserved. We also have determined that defects in the epiphyseal region of both forelimbs and hind limbs in the axolotl are regenerated only when the defect is small. As is the case with defects in the diaphysis, there is a critical size above which the endogenous regenerative response is not sufficient to regenerate the joint. This non-regenerative response in an animal that has the ability to regenerate perfectly provides the opportunity to screen for the signaling pathways to induce regeneration of articular cartilage and joints.
Microarray Analysis of microRNA Expression during Axolotl Limb Regeneration
Holman, Edna C.; Campbell, Leah J.; Hines, John; Crews, Craig M.
2012-01-01
Among vertebrates, salamanders stand out for their remarkable capacity to quickly regrow a myriad of tissues and organs after injury or amputation. The limb regeneration process in axolotls (Ambystoma mexicanum) has been well studied for decades at the cell-tissue level. While several developmental genes are known to be reactivated during this epimorphic process, less is known about the role of microRNAs in urodele amphibian limb regeneration. Given the compelling evidence that many microRNAs tightly regulate cell fate and morphogenetic processes through development and adulthood by modulating the expression (or re-expression) of developmental genes, we investigated the possibility that microRNA levels change during limb regeneration. Using two different microarray platforms to compare the axolotl microRNA expression between mid-bud limb regenerating blastemas and non-regenerating stump tissues, we found that miR-21 was overexpressed in mid-bud blastemas compared to stump tissue. Mature A. mexicanum (“Amex”) miR-21 was detected in axolotl RNA by Northern blot and differential expression of Amex-miR-21 in blastema versus stump was confirmed by quantitative RT-PCR. We identified the Amex Jagged1 as a putative target gene for miR-21 during salamander limb regeneration. We cloned the full length 3′UTR of Amex-Jag1, and our in vitro assays demonstrated that its single miR-21 target recognition site is functional and essential for the response of the Jagged1 gene to miR-21 levels. Our findings pave the road for advanced in vivo functional assays aimed to clarify how microRNAs such as miR-21, often linked to pathogenic cell growth, might be modulating the redeployment of developmental genes such as Jagged1 during regenerative processes. PMID:23028429
Microarray analysis of microRNA expression during axolotl limb regeneration.
Directory of Open Access Journals (Sweden)
Edna C Holman
Full Text Available Among vertebrates, salamanders stand out for their remarkable capacity to quickly regrow a myriad of tissues and organs after injury or amputation. The limb regeneration process in axolotls (Ambystoma mexicanum has been well studied for decades at the cell-tissue level. While several developmental genes are known to be reactivated during this epimorphic process, less is known about the role of microRNAs in urodele amphibian limb regeneration. Given the compelling evidence that many microRNAs tightly regulate cell fate and morphogenetic processes through development and adulthood by modulating the expression (or re-expression of developmental genes, we investigated the possibility that microRNA levels change during limb regeneration. Using two different microarray platforms to compare the axolotl microRNA expression between mid-bud limb regenerating blastemas and non-regenerating stump tissues, we found that miR-21 was overexpressed in mid-bud blastemas compared to stump tissue. Mature A. mexicanum ("Amex" miR-21 was detected in axolotl RNA by Northern blot and differential expression of Amex-miR-21 in blastema versus stump was confirmed by quantitative RT-PCR. We identified the Amex Jagged1 as a putative target gene for miR-21 during salamander limb regeneration. We cloned the full length 3'UTR of Amex-Jag1, and our in vitro assays demonstrated that its single miR-21 target recognition site is functional and essential for the response of the Jagged1 gene to miR-21 levels. Our findings pave the road for advanced in vivo functional assays aimed to clarify how microRNAs such as miR-21, often linked to pathogenic cell growth, might be modulating the redeployment of developmental genes such as Jagged1 during regenerative processes.
International Nuclear Information System (INIS)
2004-09-01
INDAG, so far, has been the only IAEA group to publish its Newsletter regularly before each General Conference Meeting. It is no doubt mainly this motivation for communication with complete transparency, coupled with expert advice, that led the independent panel for the evaluation of IAEA's nuclear desalination activities to highly commend INDAG for its actions. This time, INDAG brings you some concrete results of the International cooperation activities, strongly supported by INDAG and carried out under the aegis of IAEA's INT/4/134 programme: Thus, the Kalpakkam nuclear desalination complex in India is nearly completed, the Pakistani project for desalination with the Karachi nuclear power plant is now well on the way. At the same time, two technical and economic feasibility studies of nuclear desalination have also been completed. The final report on the feasibility of SMART + MED based integrated desalination system for the Madura island in Indonesia (Collaboration between South Korea and Indonesia) has already been published. That from the French -Tunisian collaboration, known as the TUNDESAL project, would come out as this Newsletter reaches you. As INDAG has consistently tried to communicate, these two studies have independently concluded that nuclear desalination is indeed a viable option for the future. The CRP on the economic assessment of site-specific cases, launched after INDAG's recommendation, continues to move forward. It was indeed the revised new models in DEEP that permitted the comprehensive economic evaluation of desalination costs in the two international feasibility studies
ITER EDA newsletter. V. 6, no. 2
International Nuclear Information System (INIS)
1997-02-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter reports on the ITER divertor development project and its objectives; contains a report on the 16th Energy IAEA Fusion Conference (ITER and other Tokamak Issues) held in Montreal, Canada; 287 papers were selected by the Programme Committee for presentation and 178 posters were presented. 3 figs
Network based transcription factor analysis of regenerating axolotl limbs
Directory of Open Access Journals (Sweden)
Cameron Jo Ann
2011-03-01
Full Text Available Abstract Background Studies on amphibian limb regeneration began in the early 1700's but we still do not completely understand the cellular and molecular events of this unique process. Understanding a complex biological process such as limb regeneration is more complicated than the knowledge of the individual genes or proteins involved. Here we followed a systems biology approach in an effort to construct the networks and pathways of protein interactions involved in formation of the accumulation blastema in regenerating axolotl limbs. Results We used the human orthologs of proteins previously identified by our research team as bait to identify the transcription factor (TF pathways and networks that regulate blastema formation in amputated axolotl limbs. The five most connected factors, c-Myc, SP1, HNF4A, ESR1 and p53 regulate ~50% of the proteins in our data. Among these, c-Myc and SP1 regulate 36.2% of the proteins. c-Myc was the most highly connected TF (71 targets. Network analysis showed that TGF-β1 and fibronectin (FN lead to the activation of these TFs. We found that other TFs known to be involved in epigenetic reprogramming, such as Klf4, Oct4, and Lin28 are also connected to c-Myc and SP1. Conclusions Our study provides a systems biology approach to how different molecular entities inter-connect with each other during the formation of an accumulation blastema in regenerating axolotl limbs. This approach provides an in silico methodology to identify proteins that are not detected by experimental methods such as proteomics but are potentially important to blastema formation. We found that the TFs, c-Myc and SP1 and their target genes could potentially play a central role in limb regeneration. Systems biology has the potential to map out numerous other pathways that are crucial to blastema formation in regeneration-competent limbs, to compare these to the pathways that characterize regeneration-deficient limbs and finally, to identify stem
Plant breeding and genetics newsletter. No. 14
International Nuclear Information System (INIS)
2004-12-01
These last six months, the Plant Breeding and Genetics (PBG) Section of the Joint FAO/IAEA Division (NAFA/AGE) implemented five Research Coordination Meetings (RCMs) and one Consultants Meeting for a new Coordinated Research Project (CRP) on 'Molecular tools for quality improvement in vegetatively propagated crops including banana and cassava' (8-11 November 2004, Vienna). Other salient points were the training courses we implemented this semester in the framework of different Technical Cooperation (TC) projects.Details about these activities inside this Newsletter
Computer Program Newsletter No. 7
International Nuclear Information System (INIS)
Magnuson, W.G. Jr.
1982-09-01
This issue of the Computer Program Newsletter updates an earlier newsletter (Number 2, September 1979) and focuses on electrical network analysis computer programs. In particular, five network analysis programs (SCEPTRE, SPICE2, NET2, CALAHAN, and EMTP) will be described. The objective of this newsletter will be to provide a very brief description of the input syntax and semantics for each program, highlight their strong and weak points, illustrate how the programs are run at Lawrence Livermore National Laboratory using the Octopus computer network, and present examples of input for each of the programs to illustrate some of the features of each program. In a sense, this newsletter can be used as a quick reference guide to the programs
International Neutron Radiography Newsletter
DEFF Research Database (Denmark)
Domanus, Joseph Czeslaw
1986-01-01
At the First World Conference on Neutron Radiography i t was decided to continue the "Neutron Radiography Newsletter", published previously by J.P. Barton, as the "International Neutron Radiography Newsletter" (INRNL), with J.C. Doraanus as editor. The British Journal of Non-Destructive Testing...
Insect pest control newsletter. No. 67, July 2006
International Nuclear Information System (INIS)
2006-07-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on insect pest control, as well as news items on other activities of the Insect Pest Control Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Insect pest control newsletter, No. 71, July 2008
International Nuclear Information System (INIS)
2008-07-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on insect pest control, as well as news items on other activities of the Insect Pest Control Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Insect pest control newsletter. No. 66, January 2006
International Nuclear Information System (INIS)
2006-01-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on insect pest control, as well as news items on other activities of the Insect Pest Control Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Insect pest control newsletter, No. 72, January 2009
International Nuclear Information System (INIS)
2009-01-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on insect pest control, as well as news items on other activities of the Insect Pest Control Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Insect pest control newsletter. No. 69, July 2007
International Nuclear Information System (INIS)
2007-07-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on insect pest control, as well as news items on other activities of the Insect Pest Control Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Insect pest control newsletter. No. 68, January 2007
International Nuclear Information System (INIS)
2007-01-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on insect pest control, as well as news items on other activities of the Insect Pest Control Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Insect pest control newsletter, No. 70, January 2008
International Nuclear Information System (INIS)
2008-01-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on insect pest control, as well as news items on other activities of the Insect Pest Control Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
EDIN-USVI Clean Energy Quarterly: Volume 2, Issue 1, June 2012 (Newsletter)
Energy Technology Data Exchange (ETDEWEB)
2012-06-01
This quarterly newsletter provides timely news and information about the plans and progress of the Energy Development in Island Nations-U.S. Virgin Islands pilot project, including significant events and milestones, work undertaken by each of the working groups, and project-related technology deployment efforts.
ITER ITA newsletter. No. 6, July 2003
International Nuclear Information System (INIS)
2003-09-01
This issue of ITER ITA (ITER transitional Arrangements) newsletter contains concise information about ITER related activities. One of them was the farewell party for for Annick Lyraud and Robert Aymar, who will take up his position as Director-General of CERN in January 2004, another is information about Dr. Yasuo Shimomura, ITER interim project leader, and ITER technical work during the transitional arrangements
ITER EDA Newsletter. V. 4, no. 5
International Nuclear Information System (INIS)
1995-05-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter contains comments on the ITER project by the Permanent Representative of the Russian Federation to the International Organizations in Vienna; a report on the ITER Magnet Technical Meeting held at the Joint Work Site at Naka, Japan, April 19-21, 1995; and a contribution entitled ''ITER spouses cross the cultures''
Soils newsletter. Vol. 28, no. 2, January 2006
International Nuclear Information System (INIS)
2006-01-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Soils newsletter. Vol. 28, no. 1, July 2005
International Nuclear Information System (INIS)
2005-07-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Soils newsletter. Vol. 29, no. 2, December 2006
International Nuclear Information System (INIS)
2006-12-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Soils newsletter. Vol. 29, no. 1, July 2006
International Nuclear Information System (INIS)
2006-07-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Soils newsletter. Vol. 30, no. 1, July 2007
International Nuclear Information System (INIS)
2007-07-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Soils newsletter. Vol. 26, no. 2, January 2004
International Nuclear Information System (INIS)
2004-01-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Soils newsletter. Vol. 27, no. 2, December 2004
International Nuclear Information System (INIS)
2004-12-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Soils newsletter. Vol. 27, no. 1, June 2004
International Nuclear Information System (INIS)
2004-06-01
This issue of the Newsletter reports on status of technical cooperation projects, research coordination meetings and training courses offered on Soil, Water and Nutrient Management and staff related news at the Soil and Water Management and Crop Nutrition Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture
Neural crest does not contribute to the neck and shoulder in the axolotl (Ambystoma mexicanum).
Epperlein, Hans-Henning; Khattak, Shahryar; Knapp, Dunja; Tanaka, Elly M; Malashichev, Yegor B
2012-01-01
A major step during the evolution of tetrapods was their transition from water to land. This process involved the reduction or complete loss of the dermal bones that made up connections to the skull and a concomitant enlargement of the endochondral shoulder girdle. In the mouse the latter is derived from three separate embryonic sources: lateral plate mesoderm, somites, and neural crest. The neural crest was suggested to sustain the muscle attachments. How this complex composition of the endochondral shoulder girdle arose during evolution and whether it is shared by all tetrapods is unknown. Salamanders that lack dermal bone within their shoulder girdle were of special interest for a possible contribution of the neural crest to the endochondral elements and muscle attachment sites, and we therefore studied them in this context. We grafted neural crest from GFP+ fluorescent transgenic axolotl (Ambystoma mexicanum) donor embryos into white (d/d) axolotl hosts and followed the presence of neural crest cells within the cartilage of the shoulder girdle and the connective tissue of muscle attachment sites of the neck-shoulder region. Strikingly, neural crest cells did not contribute to any part of the endochondral shoulder girdle or to the connective tissue at muscle attachment sites in axolotl. Our results in axolotl suggest that neural crest does not serve a general function in vertebrate shoulder muscle attachment sites as predicted by the "muscle scaffold theory," and that it is not necessary to maintain connectivity of the endochondral shoulder girdle to the skull. Our data support the possibility that the contribution of the neural crest to the endochondral shoulder girdle, which is observed in the mouse, arose de novo in mammals as a developmental basis for their skeletal synapomorphies. This further supports the hypothesis of an increased neural crest diversification during vertebrate evolution.
Neural crest does not contribute to the neck and shoulder in the axolotl (Ambystoma mexicanum.
Directory of Open Access Journals (Sweden)
Hans-Henning Epperlein
Full Text Available BACKGROUND: A major step during the evolution of tetrapods was their transition from water to land. This process involved the reduction or complete loss of the dermal bones that made up connections to the skull and a concomitant enlargement of the endochondral shoulder girdle. In the mouse the latter is derived from three separate embryonic sources: lateral plate mesoderm, somites, and neural crest. The neural crest was suggested to sustain the muscle attachments. How this complex composition of the endochondral shoulder girdle arose during evolution and whether it is shared by all tetrapods is unknown. Salamanders that lack dermal bone within their shoulder girdle were of special interest for a possible contribution of the neural crest to the endochondral elements and muscle attachment sites, and we therefore studied them in this context. RESULTS: We grafted neural crest from GFP+ fluorescent transgenic axolotl (Ambystoma mexicanum donor embryos into white (d/d axolotl hosts and followed the presence of neural crest cells within the cartilage of the shoulder girdle and the connective tissue of muscle attachment sites of the neck-shoulder region. Strikingly, neural crest cells did not contribute to any part of the endochondral shoulder girdle or to the connective tissue at muscle attachment sites in axolotl. CONCLUSIONS: Our results in axolotl suggest that neural crest does not serve a general function in vertebrate shoulder muscle attachment sites as predicted by the "muscle scaffold theory," and that it is not necessary to maintain connectivity of the endochondral shoulder girdle to the skull. Our data support the possibility that the contribution of the neural crest to the endochondral shoulder girdle, which is observed in the mouse, arose de novo in mammals as a developmental basis for their skeletal synapomorphies. This further supports the hypothesis of an increased neural crest diversification during vertebrate evolution.
Soils Newsletter. V. 15, no. 2
International Nuclear Information System (INIS)
1992-12-01
This newsletter contains reports of the five Research Co-ordination Meetings held in 1992; the descriptions of the meetings on ''The use of nuclear and related techniques in the management of nitrogen-fixing trees for enhancing soil fertility and soil conservation'' and ''The use of isotope studies on increasing and stabilizing plant productivity in low phosphate and semi-arid and sub-humid soils of the tropics and sub-tropics'' contain excerpts from presented reports. Also included is a feature on some of the the Technical Co-operation Projects coming under the umbrella of the Regional African Project on Biological Nitrogen Fixation
Practice tip. Producing newsletters - criteria for success.
Eckermann, Sarah Louise; McIntyre, Ellen; Magarey, Anne
2007-01-01
Newsletters, while informal when compared to peer reviewed journals and organisational reports, are a popular communication tool used to provide and share information, for and about people with a common interest or need. Newsletters are an effective way to build networks and improve communication. As the editors of several newsletters in primary health care, the authors have developed criteria that aim to increase the success of a newsletter.
Expression of Msx-2 during development, regeneration, and wound healing in axolotl limbs.
Carlson, M R; Bryant, S V; Gardiner, D M
1998-12-15
Msx genes are transcription factors that are expressed during embryogenesis of developing appendages in regions of epithelial-mesenchymal interactions. Various lines of evidence indicate that these genes function to maintain embryonic tissues in an undifferentiated, proliferative state. We have identified the axolotl homolog of Msx-2, and investigated its expression during limb development, limb regeneration, and wound healing. As in limb buds of higher vertebrates, axolotl Msx-2 is expressed in the apical epidermis and mesenchyme; however, its expression domain is more extensive, reflecting the broader region of the apical epidermal cap in amphibians. Msx-2 expression is downregulated at late stages of limb development, but is reexpressed within one hour after limb amputation. Msx-2 is also reexpressed during wound healing, and may be essential in the early stages of initiation of the limb regeneration cascade.
CERN Diversity Newsletter - November 2015
Kaltenhauser, Kristin; CERN. Geneva. HR Department
2015-01-01
Quarterly CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter
CERN Diversity Newsletter - April 2017
AUTHOR|(CDS)2069427; Koutava, Ioanna; CERN. Geneva. HR Department
2017-01-01
The CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter
CERN Diversity Newsletter - March 2016
Kaltenhauser, Kristin; CERN. Geneva. HR Department
2016-01-01
Quarterly CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter
CERN Diversity Newsletter - September 2016
Guinot, Genevieve
2016-01-01
Quarterly CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter
Insect and Pest Control Newsletter, No. 78, January 2012
International Nuclear Information System (INIS)
2012-01-01
The IPC Newsletter is prepared twice per year by the Insect Pest Control Subprogramme, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture. Contents: To Our Readers; Staff; Forthcoming Events; Past Events; Technical Cooperation Projects; Coordinated Research Projects and Research Coordination Meetings; Developments at the Insect Pest Control Laboratory; Reports; Announcements; In Memoriam; Other News; Relevant Published Articles; Papers in Peer Reviewed Journals; Priced and Unpriced Publications
Insect and Pest Control Newsletter, No. 78, January 2012
Energy Technology Data Exchange (ETDEWEB)
NONE
2012-01-15
The IPC Newsletter is prepared twice per year by the Insect Pest Control Subprogramme, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture. Contents: To Our Readers; Staff; Forthcoming Events; Past Events; Technical Cooperation Projects; Coordinated Research Projects and Research Coordination Meetings; Developments at the Insect Pest Control Laboratory; Reports; Announcements; In Memoriam; Other News; Relevant Published Articles; Papers in Peer Reviewed Journals; Priced and Unpriced Publications
Jiang, Peng; Nelson, Jeffrey D.; Leng, Ning; Collins, Michael; Swanson, Scott; Dewey, Colin N.; Thomson, James A.; Stewart, Ron
2016-01-01
The axolotl (Ambystoma mexicanum) has long been the subject of biological research, primarily owing to its outstanding regenerative capabilities. However, the gene expression programs governing its embryonic development are particularly underexplored, especially when compared to other amphibian model species. Therefore, we performed whole transcriptome polyA+ RNA sequencing experiments on 17 stages of embryonic development. As the axolotl genome is unsequenced and its gene annotation is incomplete, we built de novo transcriptome assemblies for each stage and garnered functional annotation by comparing expressed contigs with known genes in other organisms. In evaluating the number of differentially expressed genes over time, we identify three waves of substantial transcriptome upheaval each followed by a period of relative transcriptome stability. The first wave of upheaval is between the one and two cell stage. We show that the number of differentially expressed genes per unit time is higher between the one and two cell stage than it is across the mid-blastula transition (MBT), the period of zygotic genome activation. We use total RNA sequencing to demonstrate that the vast majority of genes with increasing polyA+ signal between the one and two cell stage result from polyadenylation rather than de novo transcription. The first stable phase begins after the two cell stage and continues until the mid-blastula transition, corresponding with the pre-MBT phase of transcriptional quiescence in amphibian development. Following this is a peak of differential gene expression corresponding with the activation of the zygotic genome and a phase of transcriptomic stability from stages 9 to 11. We observe a third wave of transcriptomic change between stages 11 and 14, followed by a final stable period. The last two stable phases have not been documented in amphibians previously and correspond to times of major morphogenic change in the axolotl embryo: gastrulation and
Wind Program Newsletter: October 2014 Edition (Newsletter)
Energy Technology Data Exchange (ETDEWEB)
2014-10-01
The U.S. Department of Energy's Wind Program Newsletter, supported by the EERE Wind and Water Power Technologies office, highlights the Wind Program's key activities, events, and funding opportunities.
ITER EDA newsletter. V. 6, no. 4
International Nuclear Information System (INIS)
1997-04-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter reports on the Toroidal Field Model Coil Project (Coil System, Objectives, Design, Project Management, Testing); contains a report of A Combined Workshop of Confinement Modeling and Database and Confinement and Transport Expert Groups held at the San Diego ITER Joint Work Site from April 14. to 18. Progress and status on implementing the ITER Confinement R and D needs as specified at the last Workshops of the Expert Groups in Montreal (Oct. 1996) were reported. 7 figs, 1 tab
Nuclear data newsletter. No. 41, May 2006
International Nuclear Information System (INIS)
2006-05-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres
Nuclear data newsletter. No. 40, September 2005
International Nuclear Information System (INIS)
2005-09-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres
Plant breeding and genetics newsletter. No. 3
International Nuclear Information System (INIS)
1999-06-01
This third issue of the Plant Breeding and Genetics Newsletter highlights forthcoming events including regional (Afra) training course on 'molecular characterization of genetic biodiversity in traditional and neglected crops selected for improvement through mutation techniques' and seminar on 'mutation techniques and biotechnology for tropical and subtropical plant improvement in Asia and Pacific regions'. Status of existing co-ordinated and technical co-operation research projects is also summarized
CERN Diversity Newsletter - July 2015
Kaltenhauser, Kristin; CERN. Geneva. HR Department
2015-01-01
The first official edition of the CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter
Animal production and health newsletter. No. 45, December 2006
International Nuclear Information System (INIS)
2006-12-01
Once again the year is at end and a new exciting year lies ahead of us. The past year has been a busy time for all staff in the subprogramme. Apart from our regular Coordinated Research Project (CRP) activities and our technical support given to national and regional Technical Cooperation (TC) projects, we were involved in the technical evaluation of applications for new TC projects by Member States for the 2007/2008 biennial project cycle. We have also prepared the IAEA's 2008/2009 Work and Budget Programme. It is hoped that our inputs will serve the best interests of our Member States. As with previous newsletters, I want to introduce a topic to hopefully stimulate discussion and debate and encourage interactions between all. It has been well discussed in previous newsletters that the trend towards intensification of livestock production in developing countries presents both opportunities and risks. The potential opportunities are the flow-on benefits to the local economy and producers and the potential risks are the flow-on costs to the environment, livestock health and welfare and human health, through increased chemical and nutrient pollution, disease transmission and centralization of feed resources. Understanding nutrition is one of the keys to taking advantage of the opportunities and minimizing the risks
A Canadian recycling newsletter. Final phase
Energy Technology Data Exchange (ETDEWEB)
1979-01-01
A study was performed to publish a Canadian recycling newsletter, to be distributed gradually throughout the country. This report reviews the format, data collection procedures, printing, mailing, advertising, marketing, promotion, and finances of the publication. In the final phase of the study, publication and distribution was to extend to various segments of the secondary materials industry. This would include publishing articles and industry briefs related to the ferrous and non-ferrous metals industry. The publication would be increased to 12 pages and would attempt to become financially self-sufficient. In this phase, the newsletter became firmly established as the voice of Canada's secondary materials market, especially waste paper, where the price guide published by the newsletter became a sort of recognized standard. It was found that financially independent operation was achieved within one year. The newsletter was published on schedule and reader response was positive. Examples of the newsletter, called Recoup, are included in the appendix.
Soils newsletter. V, 16, no. 1
International Nuclear Information System (INIS)
1993-07-01
The bulk of this newsletter is comprised of reports of meetings held between September 1992 and April 1993. Extracts from reports presented at three meetings are included: the second Research Co-ordination Meeting of the Co-ordinated Research Programme on ''The Use of Molecular Biology in Microbial Ecology''; the final Research Co-ordination Meeting of the Co-ordinated Research Programme on ''The Use of Nuclear and Isotopic Techniques to Improve Crop Production on Salt-Affected Soils''; and the third Research Workshop of the Regional African Project on Biological Nitrogen Fixation. There is also a brief summary of some of the current Technical Co-operation Projects in the Africa region
Ackerly, Kerri L; Ward, Andrea B
2015-12-01
Environmental conditions during early development in ectothermic vertebrates can lead to variation in vertebral number among individuals of the same species. It is often seen that individuals of a species raised at cooler temperatures have more vertebrae than individuals raised at warmer temperatures, although the functional consequences of this variation in vertebral number on swimming performance are relatively unclear. To investigate this relationship, we tested how vertebral number in axolotls (Ambystoma mexicanum) affected performance of aquatic escape responses (C-starts). Axolotls were reared at four temperatures (12-24°C) encompassing their natural thermal range and then transitioned to a mean temperature (18°C) three months before C-starts were recorded. Our results showed variation in vertebral number, but that variation was not significantly affected by developmental temperature. C-start performance among axolotls was significantly correlated with caudal vertebral number, and individuals with more caudal vertebrae were able to achieve greater curvature more quickly during their responses than individuals with fewer vertebrae. However, our results show that these individuals did not achieve greater displacements or velocities, and that developmental temperature did not have any effect on C-start performance. We highlight that the most important aspects of escape swim performance (i.e., how far individuals get from a threat and how quickly they move the most important parts of the body away from that threat) are consistent across individuals regardless of developmental temperature and morphological variation. Copyright © 2015 Elsevier GmbH. All rights reserved.
Nuclear data newsletter, No. 45, May 2008
International Nuclear Information System (INIS)
2008-05-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and database news concerning nuclear data libraries, computer codes and coordinated research projects and lists selected charts, reports and documents on nuclear data. Further it contains meeting reports of the Second Research Coordination Meeting (RCM) on Reference Database for Neutron Activation Analysis, 7?9 May 2007, IAEA Vienna
ITER EDA newsletter. V. 5, no. 10
International Nuclear Information System (INIS)
1996-10-01
This issue of the newsletter on the Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on the Fifth ITER Technical Meeting on Safety, Environment, and Regulatory Approval, held September 29 - October 7, 1996 at the ITER San Diego Joint Work Site; and a report on the Fifth ITER Diagnostics Expert Group Workshop and Technical Meeting on Diagnostics held in Montreal, Canada, 12-13 October 1996
EVALUATION OF THE MASTER MARKETER NEWSLETTER
McCorkle, Dean A.; Waller, Mark L.; Amosson, Stephen H.; Smith, Jackie; Bevers, Stanley J.; Borchardt, Robert
2001-01-01
Several support programs have been developed to help support, reinforce, enhance, and improve the effectiveness of the educational experience of Master Marketer graduates and other marketing club participants. One of those products, the Master Marketer Newsletter, is currently mailed to over 700 Master Marketer graduates and Extension faculty on a quarterly basis. In the June 2000 newsletter, a questionnaire was sent to newsletter recipients asking them to evaluate the various sections of the...
Nuclear power newsletter Vol. 3, no. 2, June 2006
International Nuclear Information System (INIS)
2006-06-01
The topics presented in this newsletter are: The 7th IAEA - FORATOM Joint Workshop on Successful Management of Organizational Change; Message from the Director of the Division of Nuclear Power; Nuclear power plant operation; Management system, infrastructure and training; International Project on Innovative Nuclear Reactors and Fuel Cycles; Technology developments and applications for advanced reactors
EDIN-USVI Clean Energy Quarterly: Volume 1, Issue 3, September 2011 (Newsletter)
Energy Technology Data Exchange (ETDEWEB)
2011-09-01
This quarterly newsletter provides timely news and information about the plans and progress of the Energy Development in Island Nations-U.S. Virgin Islands pilot project, including significant events and milestones, work undertaken by each of the five working groups, and project-related renewable energy and energy efficiency educational outreach and technology deployment efforts.
Spent fuel management newsletter. No. 2
International Nuclear Information System (INIS)
1993-04-01
This issue of the newsletter consists of two parts. The first part describes the IAEA Secretariat activities - work and programme of the Nuclear Materials and Fuel Cycle Technology Section of the Division of Nuclear Fuel Cycle and Waste Management, recent and planned meetings and publications, Technical Co-operation projects, Co-ordinated Research programmes. The second part contains country reports - national programmes on spent fuel management: current and planned storage and reprocessing capacities, spent fuel arisings, safety, transportation, storage and treatment of spent fuel
Spent fuel management newsletter. No. 2
Energy Technology Data Exchange (ETDEWEB)
NONE
1993-04-01
This issue of the newsletter consists of two parts. The first part describes the IAEA Secretariat activities - work and programme of the Nuclear Materials and Fuel Cycle Technology Section of the Division of Nuclear Fuel Cycle and Waste Management, recent and planned meetings and publications, Technical Co-operation projects, Co-ordinated Research programmes. The second part contains country reports - national programmes on spent fuel management: current and planned storage and reprocessing capacities, spent fuel arisings, safety, transportation, storage and treatment of spent fuel.
Axolotl cells and tissues enhances cutaneous wound healing in mice
DEMIRCAN, Turan; KESKIN, Ilknur; GUNAL, Yalcin; ILHAN, Ayse Elif; KOLBASI, Bircan; OZTURK, Gurkan
2017-01-01
Adult mammalian skin wound repair is defective due to loss of the regulation in balancing the complete epithelial regeneration and excessive connective tissue production, and this repair process commonly results in scar tissue formation. However, unlike mammals, adult salamanders repair the wounds by regeneration compared to scarring. To elucidate the healing capability of a salamander, Axolotl, in a different species, here we addressed this question by treating the wounds in mice with Axolot...
Nuclear data newsletter. No. 43, May 2007
International Nuclear Information System (INIS)
2007-05-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres. Further it contains meeting reports of selected technical meetings
Hyperbaric oxygen therapy in a true regenerative environment, the regenerating limb of the axolotl
DEFF Research Database (Denmark)
Hansen, Kasper; Lauridsen, Henrik; Pedersen, Michael
2012-01-01
vertebrates such as the urodele amphibians (salamanders and newts), are excellent animal models for regenerative studies. The iconic Mexican axolotl (Ambystoma mexicanum) is capable of regenerating whole limbs, tail, jaw, and many inner organs, by dedifferentiation of cells to form a blastema (collection...
XRF newsletter No. 12, December 2006
International Nuclear Information System (INIS)
2007-01-01
This periodical XRF Newsletter is to inform the XRF laboratories in IAEA Member States on recent developments in the field of XRF spectrometry and to exchange views on fundamental and applied aspects of sampling, sample preparation, instrumentation, quality control, etc. A few selected examples of the recent activities in the IAEA XRF Laboratory and its results in the field of XRF are presented: Development of a flexible multi-channel digital spectrometer; Support to Technical Cooperation projects. Conferences and workshops in this field are listed
Yu, Haining; Gao, Jiuxiang; Lu, Yiling; Guang, Huijuan; Cai, Shasha; Zhang, Songyan; Wang, Yipeng
2013-11-01
Lysozymes are key proteins that play important roles in innate immune defense in many animal phyla by breaking down the bacterial cell-walls. In this study, we report the molecular cloning, sequence analysis and phylogeny of the first caudate amphibian g-lysozyme: a full-length spleen cDNA library from axolotl (Ambystoma mexicanum). A goose-type (g-lysozyme) EST was identified and the full-length cDNA was obtained using RACE-PCR. The axolotl g-lysozyme sequence represents an open reading frame for a putative signal peptide and the mature protein composed of 184 amino acids. The calculated molecular mass and the theoretical isoelectric point (pl) of this mature protein are 21523.0 Da and 4.37, respectively. Expression of g-lysozyme mRNA is predominantly found in skin, with lower levels in spleen, liver, muscle, and lung. Phylogenetic analysis revealed that caudate amphibian g-lysozyme had distinct evolution pattern for being juxtaposed with not only anura amphibian, but also with the fish, bird and mammal. Although the first complete cDNA sequence for caudate amphibian g-lysozyme is reported in the present study, clones encoding axolotl's other functional immune molecules in the full-length cDNA library will have to be further sequenced to gain insight into the fundamental aspects of antibacterial mechanisms in caudate.
Directory of Open Access Journals (Sweden)
Finnson Kenneth
2010-02-01
Full Text Available Abstract Background Axolotls have the unique ability, among vertebrates, to perfectly regenerate complex body parts, such as limbs, after amputation. In addition, axolotls pattern developing and regenerating autopods from the anterior to posterior axis instead of posterior to anterior like all tetrapods studied to date. Sonic hedgehog is important in establishing this anterior-posterior axis of limbs in all tetrapods including axolotls. Interestingly, its expression is conserved (to the posterior side of limb buds and blastemas in axolotl limbs as in other tetrapods. It has been suggested that BMP-2 may be the secondary mediator of sonic hedgehog, although there is mounting evidence to the contrary in mice. Since BMP-2 expression is on the anterior portion of developing and regenerating limbs prior to digit patterning, opposite to the expression of sonic hedgehog, we examined whether BMP-2 expression was dependent on sonic hedgehog signaling and whether it affects patterning of the autopod during regeneration. Results The expression of BMP-2 and SOX-9 in developing and regenerating axolotl limbs corresponded to the first digits forming in the anterior portion of the autopods. The inhibition of sonic hedgehog signaling with cyclopamine caused hypomorphic limbs (during development and regeneration but did not affect the expression of BMP-2 and SOX-9. Overexpression of BMP-2 in regenerating limbs caused a loss of digits. Overexpression of Noggin (BMP inhibitor in regenerating limbs also resulted in a loss of digits. Histological analysis indicated that the loss due to BMP-2 overexpression was the result of increased cell condensation and apoptosis while the loss caused by Noggin was due to a decrease in cell division. Conclusion The expression of BMP-2 and its target SOX-9 was independent of sonic hedgehog signaling in developing and regenerating limbs. Their expression correlated with chondrogenesis and the appearance of skeletal elements has
NAWIG News: The Quarterly Newsletter of the Native American Wind Interest Group, Summer 2007
Energy Technology Data Exchange (ETDEWEB)
2007-06-01
DOE's Wind Powering America program has initiated a quarterly NAWIG newsletter to present Native American wind information, including projects, interviews with pioneers, issues, WPA activities, and related events.
ITER CTA newsletter. No. 13, October 2002
International Nuclear Information System (INIS)
2002-11-01
This ITER CTA newsletter issue comprises concise information about an ITER related meeting concerning the joint implementation of ITER - the fifth ITER Negotiations Meeting - which was held in Toronto, Canada, 19-20 September, 2002, and information about assessment of the possible ITER site in Clarington, Ontario, Canada, which was the subject of the first official stage of the Joint Assessment of Specific Sites (JASS) for the ITER Project. This assessment was completed just before the Fifth ITER Negotiations Meeting
Animal Production and Health Newsletter. No. 15
International Nuclear Information System (INIS)
1991-12-01
This newsletter contains brief reviews of the meetings held between September and November, 1991, and a list of the nine co-ordinated research projects (CRPs) organized by the Animal Production and Health Section of the Joint FAO/IAEA Division is given. A tenth CRP, focussing on the development of supplementation strategies for milk-producing animals in tropical and subtropical environments, is currently being planned. Developments at the Animal Production Unit of the IAEA Laboratory, Seibersdorf are detailed
Energy Technology Data Exchange (ETDEWEB)
NONE
1979-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1983-12-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1982-12-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1980-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1981-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1982-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1978-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1981-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1980-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1983-07-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1979-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
International Nuclear Information System (INIS)
1983-12-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
Soils newsletter. V. 11, no. 1
Energy Technology Data Exchange (ETDEWEB)
NONE
1988-07-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1985-01-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
Energy Technology Data Exchange (ETDEWEB)
NONE
1978-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
International Nuclear Information System (INIS)
1985-01-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1979-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
Energy Technology Data Exchange (ETDEWEB)
NONE
1984-07-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
International Nuclear Information System (INIS)
1978-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
Soils newsletter. V. 11, no. 1
International Nuclear Information System (INIS)
1988-07-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1981-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
Soils newsletter. V. 10, no. 2
Energy Technology Data Exchange (ETDEWEB)
NONE
1987-12-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter.
International Nuclear Information System (INIS)
1979-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1978-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1980-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1983-07-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1984-07-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1982-12-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1981-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1980-10-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
International Nuclear Information System (INIS)
1982-04-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
Soils newsletter. V. 10, no. 2
International Nuclear Information System (INIS)
1987-12-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
Soils newsletter. V. 23, no. 1
International Nuclear Information System (INIS)
2000-06-01
This newsletter disseminates information arising out of international cooperative efforts in the use of nuclear techniques for research into soil fertility, fertilizer usage, plant nutrition, soil moisture and irrigation. Reports of the coordinated research programmes are also highlighted in this newsletter
Carlson, Bruce M.
Flexor and extensor muscles in the upper arms of axolotls were minced and cross-transplanted. The limbs were amputated 5 and 30 days after mincing. In each experiment a high percentage of the regenerates consisted of multiple limbs. This demonstrates that the morphogenetic information which produces
Arms Control, Disarmament, and Peace Newsletters.
Atkins, Stephen
1986-01-01
Considers the research value of four types of newsletters on arms control, disarmament, and peace: direct-action, informational, scholarly, and single-issue. An annotated list of 58 newsletters includes those considered most significant of their type and recommended for library collections. (EM)
Directory of Open Access Journals (Sweden)
Kazumasa Mitogawa
Full Text Available Axolotls (Ambystoma mexicanum can completely regenerate lost limbs, whereas Xenopus laevis frogs cannot. During limb regeneration, a blastema is first formed at the amputation plane. It is thought that this regeneration blastema forms a limb by mechanisms similar to those of a developing embryonic limb bud. Furthermore, Xenopus laevis frogs can form a blastema after amputation; however, the blastema results in a terminal cone-shaped cartilaginous structure called a "spike." The causes of this patterning defect in Xenopus frog limb regeneration were explored. We hypothesized that differences in chondrogenesis may underlie the patterning defect. Thus, we focused on chondrogenesis. Chondrogenesis marker genes, type I and type II collagen, were compared in regenerative and nonregenerative environments. There were marked differences between axolotls and Xenopus in the expression pattern of these chondrogenesis-associated genes. The relative deficit in the chondrogenic capacity of Xenopus blastema cells may account for the absence of total limb regenerative capacity.
Comparison of tissue processing methods for microvascular visualization in axolotls.
Montoro, Rodrigo; Dickie, Renee
2017-01-01
The vascular system, the pipeline for oxygen and nutrient delivery to tissues, is essential for vertebrate development, growth, injury repair, and regeneration. With their capacity to regenerate entire appendages throughout their lifespan, axolotls are an unparalleled model for vertebrate regeneration, but they lack many of the molecular tools that facilitate vascular imaging in other animal models. The determination of vascular metrics requires high quality image data for the discrimination of vessels from background tissue. Quantification of the vasculature using perfused, cleared specimens is well-established in mammalian systems, but has not been widely employed in amphibians. The objective of this study was to optimize tissue preparation methods for the visualization of the microvascular network in axolotls, providing a basis for the quantification of regenerative angiogenesis. To accomplish this aim, we performed intracardiac perfusion of pigment-based contrast agents and evaluated aqueous and non-aqueous clearing techniques. The methods were verified by comparing the quality of the vascular images and the observable vascular density across treatment groups. Simple and inexpensive, these tissue processing techniques will be of use in studies assessing vascular growth and remodeling within the context of regeneration. Advantages of this method include: •Higher contrast of the vasculature within the 3D context of the surrounding tissue •Enhanced detection of microvasculature facilitating vascular quantification •Compatibility with other labeling techniques.
Plasma Physics Network Newsletter. No. 1
International Nuclear Information System (INIS)
1989-08-01
This is the first issue of a quarterly newsletter published by the International Atomic Energy Agency in order to provide news of potential interest of fusion scientists in developing countries. According to the foreword to this first issue, the purpose of the newsletter, as well as the organization called ''Third World Network'', is to ''start the process of unifying the developing country fusion community into some type of cohesive entity and to bring the efforts of the developing countries in the plasma physics research area to the attention of the world fusion community at large''. Furthermore, this first issue contains information about (i) Nuclear Fusion Research in Argentina, (ii) Chinese Fusion Efforts, (iii) Plasma and Fusion Physics in Egypt, (iv) Fusion Research in India, (v) Fusion Research in the Republic of Korea, (vi) Fusion Programmes in Malaysia, (vi) the Agency's Fusion Programme, (vii) a proposal for a workshop on computational plasma physics, sponsored by the Third World Plasma Research Network, (viii) the announcement of the formation of the ''Asian African Association for Plasma Training'', - for the promotion of the initiation/strengthening of plasma research, especially experimental, in developing countries in Asia and Africa, as well as the cooperation and sharing of technology among plasma physicists in the developing countries in the region; (ix) a communication entitled ''Fusion Research in ''Small'' Countries'', I.R. Jones, School of Physical Sciences, The Flinders University of South Australia, Bedford Park, Australia, on the desirability of the pursuit of fusion research in ''small'' countries, i.e., those countries that do not have a national fusion research programme; (x) and, finally, a newsletter on the ITER project
International Nuclear Information System (INIS)
Torres, Carlos
1999-06-01
The International Atomic Energy Agency Programme on Biosphere Modelling and Assessment (BIOMASS) Newsletter has been launched with general objectives of providing an international focal point in the area of biosphere assessment modelling, developing methods for analysis of radionuclide transfer in the biosphere for use in radiological assessment, improving modelling methods, and developing international consensus on biosphere modelling philosophies, approaches and parameter values. The main themes included in the Newsletter include radioactive waste disposal (reference biosphere), environmental releases and biosphere processes
International Nuclear Information System (INIS)
Torres, Carlos
2000-01-01
The International Atomic Energy Agency Programme on Biosphere Modelling and Assessment (BIOMASS) Newsletter has been launched with general objectives of providing an international focal point in the area of biosphere assessment modelling, developing methods for analysis of radionuclide transfer in the biosphere for use in radiological assessment, improving modelling methods, and developing international consensus on biosphere modelling philosophies, approaches and parameter values. The main themes included in the Newsletter include radioactive waste disposal (reference biosphere), environmental releases and biosphere processes
International Nuclear Information System (INIS)
Torres, Carlos
1996-12-01
The International Atomic Energy Agency Programme on Biosphere Modelling and Assessment (BIOMASS) Newsletter has been launched with general objectives of providing an international focal point in the area of biosphere assessment modelling, developing methods for analysis of radionuclide transfer in the biosphere for use in radiological assessment, improving modelling methods, and developing international consensus on biosphere modelling philosophies, approaches and parameter values. The main themes included in the Newsletter include radioactive waste disposal (reference biosphere), environmental releases and biosphere processes
International Nuclear Information System (INIS)
Torres, Carlos
1999-01-01
The International Atomic Energy Agency Programme on Biosphere Modelling and Assessment (BIOMASS) Newsletter has been launched with general objectives of providing an international focal point in the area of biosphere assessment modelling, developing methods for analysis of radionuclide transfer in the biosphere for use in radiological assessment, improving modelling methods, and developing international consensus on biosphere modelling philosophies, approaches and parameter values. The main themes included in the Newsletter include radioactive waste disposal (reference biosphere), environmental releases and biosphere processes
International Nuclear Information System (INIS)
Torres, Carlos
1998-07-01
The International Atomic Energy Agency Programme on Biosphere Modelling and Assessment (BIOMASS) Newsletter has been launched with general objectives of providing an international focal point in the area of biosphere assessment modelling, developing methods for analysis of radionuclide transfer in the biosphere for use in radiological assessment, improving modelling methods, and developing international consensus on biosphere modelling philosophies, approaches and parameter values. The main themes included in the Newsletter include radioactive waste disposal (reference biosphere), environmental releases and biosphere processes
International Nuclear Information System (INIS)
Torres, Carlos
1997-07-01
The International Atomic Energy Agency Programme on Biosphere Modelling and Assessment (BIOMASS) Newsletter has been launched with general objectives of providing an international focal point in the area of biosphere assessment modelling, developing methods for analysis of radionuclide transfer in the biosphere for use in radiological assessment, improving modelling methods, and developing international consensus on biosphere modelling philosophies, approaches and parameter values. The main themes included in the Newsletter include radioactive waste disposal (reference biosphere), environmental releases and biosphere processes
International Nuclear Information System (INIS)
Torres, Carlos
1998-01-01
The International Atomic Energy Agency Programme on Biosphere Modelling and Assessment (BIOMASS) Newsletter has been launched with general objectives of providing an international focal point in the area of biosphere assessment modelling, developing methods for analysis of radionuclide transfer in the biosphere for use in radiological assessment, improving modelling methods, and developing international consensus on biosphere modelling philosophies, approaches and parameter values. The main themes included in the Newsletter include radioactive waste disposal (reference biosphere), environmental releases and biosphere processes
Ponomareva, Larissa V; Athippozhy, Antony; Thorson, Jon S; Voss, S Randal
2015-12-01
Amphibian vertebrates are important models in regenerative biology because they present exceptional regenerative capabilities throughout life. However, it takes considerable effort to rear amphibians to juvenile and adult stages for regeneration studies, and the relatively large sizes that frogs and salamanders achieve during development make them difficult to use in chemical screens. Here, we introduce a new tail regeneration model using late stage Mexican axolotl embryos. We show that axolotl embryos completely regenerate amputated tails in 7days before they exhaust their yolk supply and begin to feed. Further, we show that axolotl embryos can be efficiently reared in microtiter plates to achieve moderate throughput screening of soluble chemicals to investigate toxicity and identify molecules that alter regenerative outcome. As proof of principle, we identified integration 1 / wingless (Wnt), transforming growth factor beta (Tgf-β), and fibroblast growth factor (Fgf) pathway antagonists that completely block tail regeneration and additional chemicals that significantly affected tail outgrowth. Furthermore, we used microarray analysis to show that inhibition of Wnt signaling broadly affects transcription of genes associated with Wnt, Fgf, Tgf-β, epidermal growth factor (Egf), Notch, nerve growth factor (Ngf), homeotic gene (Hox), rat sarcoma/mitogen-activated protein kinase (Ras/Mapk), myelocytomatosis viral oncogene (Myc), tumor protein 53 (p53), and retinoic acid (RA) pathways. Punctuated changes in the expression of genes known to regulate vertebrate development were observed; this suggests the tail regeneration transcriptional program is hierarchically structured and temporally ordered. Our study establishes the axolotl as a chemical screening model to investigate signaling pathways associated with tissue regeneration. Copyright © 2015 Elsevier Inc. All rights reserved.
International Nuclear Information System (INIS)
2000-12-01
This periodical XRF Newsletter is to inform the XRF laboratories in IAEA Member States on recent developments in the field of XRF spectrometry and to exchange views on fundamental and applied aspects of sampling, sample preparation, instrumentation, quantitation, quality control, etc. It presents the XRF activities and the main XRF results obtained at the IAEA's model XRF Laboratory in Seibersdorf and in XRF laboratories in the Member States. This Newsletter will include input from the Member States and will help the XRF laboratories to improve their analytical performance, extend the applicability range of XRF techniques and initiate co-operation. It will be distributed to current and potential end-users of the analytical services of XRF laboratories and will further promote the utilisation of this technique in environmental pollution monitoring, mineral exploration, archaeometry and industry. The first issue of the Newsletter provides the XRF laboratories with a description of the facilities, the activities and selected results obtained at the IAEA XRF Laboratory in Seibersdorf, Austria
Abdominal Distension Associated with Luminal Fungi in the Intestines of Axolotl Larvae
Directory of Open Access Journals (Sweden)
Chiara Zullian
2015-01-01
Full Text Available Axolotls show a remarkable regeneration capacity compared with higher vertebrates, regenerating missing appendages such as limbs and tail as well as other body parts (i.e., apex of the heart, forebrain, and jaw after amputations which makes this animal a very interesting research model for tissue regeneration mechanisms. Larvae are individually housed in a 20% Holtfreter’s solution within clear plastic containers. The photoperiod light : darkness cycle is 12 : 12 h. Larvae with a total body length of less than 5 cm are fed once a day with large brine shrimp and blood worm. Albino larvae appeared to have a tendency to exhibit abdominal distention. No clinical signs of illness seemed to be associated with the condition; however, these animals exhibit a relatively slower growth rate. To better characterize this condition, we performed histological sectioning for cross sectional slide preparation on wild type and albino axolotl larvae following euthanasia. The only lesion seen in the albino larvae was a thickened gut wall and the presence of fungi within the intestines. We hypothesize that this may be due to a lower efficacy of the albino larvae’s immune system.
ITER ITA Newsletter. No. 29, March 2006
International Nuclear Information System (INIS)
2006-05-01
This issue of ITER ITA (ITER transitional Arrangements) newsletter contains concise information about ITER related activities and meetings, namely, the ITER Director-General Nominee, Dr. Kaname Ikeda, took up his position as ITER Project Leader in Cadarache on 13 March, the consolidation of information technology infrastructure for ITER and about he Thirty-Fifth Meeting of the Fusion Power Co-ordinating Committee (FPCC), which was held on 28 February-1 March 2006 at the headquarters of the International Energy Agency (IEA) in Paris
ITER CTA newsletter. No. 15, December 2002
International Nuclear Information System (INIS)
2003-03-01
This ITER CTA newsletter issue contains brief information about several meetings related to ITER. One of them is the seventh ITER Negotiations Meetings that took place in Barcelona, Spain on 9-10 December 2002, another is the final ITER CTA Project Board Meeting, which took place in Barcelona, Spain on 8 December 2002 and the last one is the Third Meeting of the International Tokamak Physics Activity (ITPA) Topical Group on diagnostics held in Toki, Japan on 18-21 September 2002
ITER EDA newsletter. V. 5, no. 7
International Nuclear Information System (INIS)
1996-07-01
This issue of the Newsletter on the Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on the Tenth ITER Council Meeting, held July 24-25, 1996, in St. Petersburg, Russia; a description of the Status of the ITER EDA by the ITER Director, Dr. R. Aymar; and a report on the so-called Task Number One by the ITER Special Working Group (Basis for the Start of Explorations, presenting possible scenarios toward siting, licensing and host support)
ITER CTA newsletter. No. 12, September 2002
International Nuclear Information System (INIS)
2002-11-01
This ITER CTA newsletter issue comprises information about two ITER meetings: The meeting of the ITER CTA Project Board (PB), which took place in Toronto, Canada on 16 September 2002 on the occasion of the fifth Negotiations Meeting (N-5) and the second meeting of the International Tokamak Physics Activity (ITPA) coordinating committee, consisting of representatives from the ITPA participants and the topical physics group chairs and co-chairs, which was held at GA Technologies, San Diego, USA on 1-2 March 2002
ITER EDA newsletter. V. 5, no. 6
International Nuclear Information System (INIS)
1996-06-01
This issue of the ITER Engineering Design Activities Newsletter contains a report on the Tenth Meeting of the ITER Technical Advisory Committee; on the papers relevant to the ITER project that were presented during the 12th International Conference on Plasma-Surface Interactions in Controlled Fusion Devices held at St. Raphael, France, on 20-24 May 1996; and a note on the interrelationship between ITER and the PSI Conference, initiated more than twenty years ago by surface and solid-state physicists
Khattak, Shahryar; Schuez, Maritta; Richter, Tobias; Knapp, Dunja; Haigo, Saori L.; Sandoval-Guzmán, Tatiana; Hradlikova, Kristyna; Duemmler, Annett; Kerney, Ryan; Tanaka, Elly M.
2013-01-01
The salamander is the only tetrapod that regenerates complex body structures throughout life. Deciphering the underlying molecular processes of regeneration is fundamental for regenerative medicine and developmental biology, but the model organism had limited tools for molecular analysis. We describe a comprehensive set of germline transgenic strains in the laboratory-bred salamander Ambystoma mexicanum (axolotl) that open up the cellular and molecular genetic dissection of regeneration. We demonstrate tissue-dependent control of gene expression in nerve, Schwann cells, oligodendrocytes, muscle, epidermis, and cartilage. Furthermore, we demonstrate the use of tamoxifen-induced Cre/loxP-mediated recombination to indelibly mark different cell types. Finally, we inducibly overexpress the cell-cycle inhibitor p16INK4a, which negatively regulates spinal cord regeneration. These tissue-specific germline axolotl lines and tightly inducible Cre drivers and LoxP reporter lines render this classical regeneration model molecularly accessible. PMID:24052945
Newsletter on Science, Technology & Human Values, Number 24, June 1978.
Shelanski, Vivien B., Ed.
Two papers are presented in this newsletter: one on the political activity of scientists following World War II as a result of the Manhattan Project, and one on the political activity of scientists today. These papers are followed by two commentaries which compare the two papers. Also included in this issue are news items, a calendar of events, a…
Food and environmental protection newsletter. V. 2, no. 1
International Nuclear Information System (INIS)
1999-06-01
This issue of the Newsletter highlights forthcoming events including a training workshop on T he application of quality control/assurance in pesticide residue analysis. Excerpt of the conference on 'food irradiation '99 - the solution to food safety crisis' held in Washington, D.C. 12-14 April 1999 in also included in this issue. Status of existing co-ordinated and technical co-operation research projects is also summarized
Nuclear power newsletter Vol. 3, no. 4, December 2006
International Nuclear Information System (INIS)
2006-12-01
The topics presented in this newsletter are: The 1st Joint IAEA-EPRI Workshop on Modernization of Instrumentation and Control Systems in Nuclear Power Plants; Message from the Director of the Division of Nuclear Power; Nuclear power plant operation; Management system, infrastructure and training; International Project on Innovative Nuclear Reactors and Fuel Cycles; Technology developments and applications for advanced reactors; Planned meetings in 2007
Educating the medical community through a teratology newsletter.
Guttmacher, A E; Allen, E F
1993-01-01
To educate a geographically and professionally diverse group of health care providers about teratology in an economic and efficient manner, we developed a locally written and distributed teratology newsletter. Response to the newsletter, from readers as well as from our staff and funding agencies, suggests that such a newsletter can be a valuable tool in educating medical communities about teratology.
Educating the medical community through a teratology newsletter.
Guttmacher, A E; Allen, E F
1993-01-01
To educate a geographically and professionally diverse group of health care providers about teratology in an economic and efficient manner, we developed a locally written and distributed teratology newsletter. Response to the newsletter, from readers as well as from our staff and funding agencies, suggests that such a newsletter can be a valuable tool in educating medical communities about teratology. PMID:8434594
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ITER EDA newsletter. V. 5, no. 12
International Nuclear Information System (INIS)
1996-12-01
This issue of the newsletter on the Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on the Eleventh ITER Council Meeting held on December 17-18, 1996 in Tokyo, Japan; a report on the Eleventh Meeting of the ITER Technical Advisory Committee (TAC-11) Meeting held 3-7 December, 1996, at the ITER Naka Joint Work Site, Japan; and a report on the Fifth Workshop of the Confinement Modelling and Database Expert Group held in Montreal, Canada, October 13-16, 1996
Freedom of Speech Newsletter, September, 1975.
Allen, Winfred G., Jr., Ed.
The Freedom of Speech Newsletter is the communication medium for the Freedom of Speech Interest Group of the Western Speech Communication Association. The newsletter contains such features as a statement of concern by the National Ad Hoc Committee Against Censorship; Reticence and Free Speech, an article by James F. Vickrey discussing the subtle…
Currie, Joshua D; Kawaguchi, Akane; Traspas, Ricardo Moreno; Schuez, Maritta; Chara, Osvaldo; Tanaka, Elly M
2016-11-21
Connective tissues-skeleton, dermis, pericytes, fascia-are a key cell source for regenerating the patterned skeleton during axolotl appendage regeneration. This complexity has made it difficult to identify the cells that regenerate skeletal tissue. Inability to identify these cells has impeded a mechanistic understanding of blastema formation. By tracing cells during digit tip regeneration using brainbow transgenic axolotls, we show that cells from each connective tissue compartment have distinct spatial and temporal profiles of proliferation, migration, and differentiation. Chondrocytes proliferate but do not migrate into the regenerate. In contrast, pericytes proliferate, then migrate into the blastema and give rise solely to pericytes. Periskeletal cells and fibroblasts contribute the bulk of digit blastema cells and acquire diverse fates according to successive waves of migration that choreograph their proximal-distal and tissue contributions. We further show that platelet-derived growth factor signaling is a potent inducer of fibroblast migration, which is required to form the blastema. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.
XRF newsletter. No. 11, July 2006
International Nuclear Information System (INIS)
2006-08-01
This periodical XRF Newsletter is to inform the XRF laboratories in IAEA Member States on recent developments in the field of XRF spectrometry and to exchange views on fundamental and applied aspects of sampling, sample preparation, instrumentation, quality control, etc. A few selected examples of the recent activities in the IAEA XRF Laboratory and its results in the field of XRF are presented: Application of X ray imaging techniques to the study of the morphology of malaria mosquitoes; Preparation of insect specimens for micro-XRF analysis; Coordinated Research Project on Unification of nuclear spectrometries: integrated techniques as a new tool for material research
Wind Program Newsletter, May 2016 Edition
Energy Technology Data Exchange (ETDEWEB)
2016-05-01
The U.S. Department of Energy Wind Program Newsletter provides wind industry stakeholders and the public with information about the Wind Program R&D efforts funded by the Wind and Water Power Technologies Office. The newsletter comes out twice a year and is sent electronically to subscribers and distributed in hard copy to conference attendees.
Food and environmental protection newsletter. V. 2, no. 1
Energy Technology Data Exchange (ETDEWEB)
NONE
1999-06-01
This issue of the Newsletter highlights forthcoming events including a training workshop on {sup T}he application of quality control/assurance in pesticide residue analysis. Excerpt of the conference on `food irradiation `99 - the solution to food safety crisis` held in Washington, D.C. 12-14 April 1999 in also included in this issue. Status of existing co-ordinated and technical co-operation research projects is also summarized
Plasma Physics Network Newsletter. No. 3
International Nuclear Information System (INIS)
1991-02-01
This issue of the Newsletter contains a report on the First South-North International Workshop on Fusion Theory, Tipaza, Algeria, 17-20 September, 1990; a report in the issuance of the ''Buenos Aires Memorandum'' generated during the IV Latin American Workshop on Plasma Physics, Argentina, July 1990, and containing a proposal that the IFRC establish a ''Steering Committee on North-South Collaboration in Controlled Nuclear Fusion and Plasma Physics Research''; the announcement that the 14th International Conference on Plasma Physics and Controlled Nuclear Fusion will be held in Wuerzburg, Germany, September 30 - October 7, 1992; a list of IAEA technical committee meetings for 1991; an item on ITER news; an article ''Long-Term Physics R and D Planning (for ITER)'' by F. Engelmann; in the planned sequence of ''Reports on National Fusion Programmes'' contributions on the Chinese and Yugoslav programmes; finally, the titles and contacts for two other newsletters of potential interest, i.e., the AAAPT (Asian African Association for Plasma Training) Newsletter, and the IPG (International Physics Group-a sub-unit of the American Physical Society) Newsletter
Zhang, Songyan; Gao, Jiuxiang; Lu, Yiling; Cai, Shasha; Qiao, Xue; Wang, Yipeng; Yu, Haining
2013-08-01
Antifreeze proteins (AFPs) refer to a class of polypeptides that are produced by certain vertebrates, plants, fungi, and bacteria and which permit their survival in subzero environments. In this study, we report the molecular cloning, sequence analysis and three-dimensional structure of the axolotl antifreeze-like protein (AFLP) by homology modeling of the first caudate amphibian AFLP. We constructed a full-length spleen cDNA library of axolotl (Ambystoma mexicanum). An EST having highest similarity (∼42%) with freeze-responsive liver protein Li16 from Rana sylvatica was identified, and the full-length cDNA was subsequently obtained by RACE-PCR. The axolotl antifreeze-like protein sequence represents an open reading frame for a putative signal peptide and the mature protein composed of 93 amino acids. The calculated molecular mass and the theoretical isoelectric point (pl) of this mature protein were 10128.6 Da and 8.97, respectively. The molecular characterization of this gene and its deduced protein were further performed by detailed bioinformatics analysis. The three-dimensional structure of current AFLP was predicted by homology modeling, and the conserved residues required for functionality were identified. The homology model constructed could be of use for effective drug design. This is the first report of an antifreeze-like protein identified from a caudate amphibian.
Promoting Nutrition and Wellness Statewide through an Electronic Newsletter
Bahl, Morgan; Francis, Sarah L.
2016-01-01
The "Words on Wellness" (WOW) newsletter was designed as an electronic newsletter intended to provide research-based nutrition and wellness information to Iowans. An evaluation was conducted to assess to what extent the newsletter is being used by its readership and whether readers are making lifestyle changes as a result. Those who…
On the participation of irradiated tissues in the formation of limb regenerate in axolotls
International Nuclear Information System (INIS)
Tuchkova, S.Ya.
1976-01-01
The aim of the study was to obtain further information on the participation of irradiated tissue cells in formation of regenerated limbs after X-irradiation of axolotls and experimental restoration of the regenerational ability. Cells of irradiated tissues were labeled with H 3 -thymidine; the presence of the label in regenerated tissues would be indicative of participation of irradiated cells in the regeneration process. Irradiation dose was 700 R. 30 axolotls with irradiated limbs were intramuscularly injected with rat muscle homogenate into the right limb once a day beginning from the day of treatment. 15 similarly irradiated animals which did not receive homogenate served as a control. The authors concluded that the presence of highly labeled cells in regenerated tissues was likely to indicate the participation of irradiated tissue cells in regeneration of the limb. However, the quantitative contribution of such cells was impossible to determine since remaining irradiated tissues of the organ contained mostly unlabeled cells. It was also impossible to rule out the possibility of cell migration from non-irradiated tissues [ru
Evidence for an RNA polymerization activity in axolotl and Xenopus egg extracts.
Directory of Open Access Journals (Sweden)
Hélène Pelczar
2010-12-01
Full Text Available We have previously reported a post-transcriptional RNA amplification observed in vivo following injection of in vitro synthesized transcripts into axolotl oocytes, unfertilized (UFE or fertilized eggs. To further characterize this phenomenon, low speed extracts (LSE from axolotl and Xenopus UFE were prepared and tested in an RNA polymerization assay. The major conclusions are: i the amphibian extracts catalyze the incorporation of radioactive ribonucleotide in RNase but not DNase sensitive products showing that these products correspond to RNA; ii the phenomenon is resistant to α-amanitin, an inhibitor of RNA polymerases II and III and to cordycepin (3'dAMP, but sensitive to cordycepin 5'-triphosphate, an RNA elongation inhibitor, which supports the existence of an RNA polymerase activity different from polymerases II and III; the detection of radiolabelled RNA comigrating at the same length as the exogenous transcript added to the extracts allowed us to show that iii the RNA polymerization is not a 3' end labelling and that iv the radiolabelled RNA is single rather than double stranded. In vitro cell-free systems derived from amphibian UFE therefore validate our previous in vivo results hypothesizing the existence of an evolutionary conserved enzymatic activity with the properties of an RNA dependent RNA polymerase (RdRp.
Nuclear data newsletter, No. 44, September 2007
International Nuclear Information System (INIS)
2007-09-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and database news concerning nuclear data libraries, data processing codes and coordinated research projects and lists selected charts, reports and documents on nuclear data. Further it contains meeting reports of the Coordination of the International Network of Nuclear Structure and Decay Data Evaluators, 11?15 June 2007, St. Petersburg, Russian Federation and the Second Research Coordination Meeting on Development of a Reference Database for Ion Beam Analysis, 18?21 June 2007, IAEA Headquarters, Vienna, Austria
Food Irradiation Newsletter. V. 16, no. 1
International Nuclear Information System (INIS)
1992-05-01
This newsletter contains a report on the final FAO/IAEA Research Coordination Meeting (RCM) on the use of irradiation to control the infectivity of food-borne parasites, held in Mexico City in June, 1991, and a brief summary of the second FAO/IAEA RCM on the Asian Regional Cooperative Project on food irradiation, with emphasis on process control and acceptance. The workshops and training courses held between September and December 1991 are presented, and a short article reports the opening of the USA's first commercial food irradiator and describes the initial public reaction
2013-01-01
Background Salamanders are unique among vertebrates in their ability to completely regenerate amputated limbs through the mediation of blastema cells located at the stump ends. This regeneration is nerve-dependent because blastema formation and regeneration does not occur after limb denervation. To obtain the genomic information of blastema tissues, de novo transcriptomes from both blastema tissues and denervated stump ends of Ambystoma mexicanum (axolotls) 14 days post-amputation were sequenced and compared using Solexa DNA sequencing. Results The sequencing done for this study produced 40,688,892 reads that were assembled into 307,345 transcribed sequences. The N50 of transcribed sequence length was 562 bases. A similarity search with known proteins identified 39,200 different genes to be expressed during limb regeneration with a cut-off E-value exceeding 10-5. We annotated assembled sequences by using gene descriptions, gene ontology, and clusters of orthologous group terms. Targeted searches using these annotations showed that the majority of the genes were in the categories of essential metabolic pathways, transcription factors and conserved signaling pathways, and novel candidate genes for regenerative processes. We discovered and confirmed numerous sequences of the candidate genes by using quantitative polymerase chain reaction and in situ hybridization. Conclusion The results of this study demonstrate that de novo transcriptome sequencing allows gene expression analysis in a species lacking genome information and provides the most comprehensive mRNA sequence resources for axolotls. The characterization of the axolotl transcriptome can help elucidate the molecular mechanisms underlying blastema formation during limb regeneration. PMID:23815514
Animal production and health newsletter. No. 37
Energy Technology Data Exchange (ETDEWEB)
NONE
2002-12-01
This issue focuses on the specific biotechnological methods that have the greatest potential for livestock production and health in developing countries, and which of these require nuclear and related techniques? The consultants' meeting that we held during 2001 (http://www.iaea.org/programmes/nafa/d3/public/ gene-technologies.pdf) provided us with the answers. We have subsequently discussed these concepts further with FAO, ILRI and other partners, and have planned a series of activities over the next two years to facilitate the transition of our Sub-programme. The first is an FAO/IAEA International Symposium on 'Applications of Gene Based Technologies for Improving Animal Production and Health in Developing Countries' which will be held here in Vienna from 6 to 10 October 2003. The official announcement is included in this Newsletter. This will be followed by three inter-regional training courses, to be held during 2004 and 2005, to train scientists in developing countries on the molecular techniques currently being used in the fields of animal nutrition, genetics and disease diagnosis. Subsequently, four new CRPs will be initiated during 2005-2006, dealing with (a) rumen molecular techniques for predicting and enhancing productivity; (b) manipulation of nutrition in utero to alter gene expression; (c) characterization of small ruminant genetic resources aimed at selection for parasite resistance; and (d) improvement of diagnostic tests for African Swine Fever to assist in molecular epidemiology. The announcements for the first two have already appeared in previous Newsletters and that for the third will be in the next issue. The projects that have been approved for implementation during the next biennium (2003-2004) are listed in this Newsletter.
Animal production and health newsletter. No. 37
International Nuclear Information System (INIS)
2002-12-01
This issue focuses on the specific biotechnological methods that have the greatest potential for livestock production and health in developing countries, and which of these require nuclear and related techniques? The consultants' meeting that we held during 2001 (http://www.iaea.org/programmes/nafa/d3/public/ gene-technologies.pdf) provided us with the answers. We have subsequently discussed these concepts further with FAO, ILRI and other partners, and have planned a series of activities over the next two years to facilitate the transition of our Sub-programme. The first is an FAO/IAEA International Symposium on 'Applications of Gene Based Technologies for Improving Animal Production and Health in Developing Countries' which will be held here in Vienna from 6 to 10 October 2003. The official announcement is included in this Newsletter. This will be followed by three inter-regional training courses, to be held during 2004 and 2005, to train scientists in developing countries on the molecular techniques currently being used in the fields of animal nutrition, genetics and disease diagnosis. Subsequently, four new CRPs will be initiated during 2005-2006, dealing with (a) rumen molecular techniques for predicting and enhancing productivity; (b) manipulation of nutrition in utero to alter gene expression; (c) characterization of small ruminant genetic resources aimed at selection for parasite resistance; and (d) improvement of diagnostic tests for African Swine Fever to assist in molecular epidemiology. The announcements for the first two have already appeared in previous Newsletters and that for the third will be in the next issue. The projects that have been approved for implementation during the next biennium (2003-2004) are listed in this Newsletter
Submillimeter Array (SMA) Newsletter August 2011
Blundell, Raymond
2011-01-01
Submillimeter Array (SMA) Newsletter August 2011 Blundell, Raymond Submillimeter Array Newsletter | Number 12 | August 2011 CONTENTS 1 From the Director SCIENCE HIGHLIGHTS: 2 Faint Submillimeter Sources behind Massive Lensing Clusters 5 Millimeter Imaging of the β Pictoris Debris Disk: Evidence for a Planetesimal Belt 7 Physical Properties of the Circumnuclear Starburst Ring in the Barred Galaxy NGC1097 TECHNICAL HIGHLIGHTS: 9 ...
International Nuclear Information System (INIS)
1998-07-01
This issue of the Newsletter opens with the note on ''x-ray calibration qualities''. The IAEA Technical Report Series No.374 ''Calibration of Dosimeters Used in Radiotherapy'' (IAEA, Vienna, 1994) is intended for hospitals and SSDLs that carry out calibration of therapy level dosimeters. The second article is a report from the First Research Co-ordination Meeting (RCM) for the Coordinated Research Projects on ''the Development of a Quality Assurance Programme for Radiation Therapy Dosimetry in Developing Countries'', held at the IAEA Headquarters from 6 to 10 October 1997. The third article is also a report from the Second Research Co-ordination Meeting (RCM) for the Co-ordinated Research Projects (CRP E2 40 06) on ''Characterization and Evaluation of High-Dose Dosimetry Techniques for Quality Assurance in Radiation Processing'' which was held at the IAEA Headquarters in Vienna, from 6 through 10 October 1997. This CRP investigates the influence of various external parameters on the performance of several routine dosimeters presently in use, and a possible transfer dosimetry system for electron beams of energy less than 4 MeV
XRF newsletter, No. 13, August 2007
International Nuclear Information System (INIS)
2007-08-01
This periodical XRF Newsletter is to inform the XRF laboratories in IAEA Member States on recent developments in the field of XRF spectrometry and to exchange views on fundamental and applied aspects of sampling, sample preparation, instrumentation, quality control, etc. A few selected examples of the recent activities in the IAEA XRF Laboratory and its results in the field of XRF are presented: Application of X-ray imaging techniques for studying the morphology of malaria-transmitting mosquitoes; International workshop on X-ray Emission Techniques for Forensic Applications; First Research Coordination Meeting under Coordinated Research Project on Unification of Nuclear Spectrometry; Integrated Techniques as a New Tool for Material Research
Loong, Ai M; Chew, Shit F; Ip, Yuen K
2002-01-01
The fully grown but nonmetamorphosed (juvenile) axolotl Ambystoma mexicanum was ureogenic and primarily ureotelic in water. A complete ornithine-urea cycle (OUC) was present in the liver. Aerial exposure impeded urea (but not ammonia) excretion, leading to a decrease in the percentage of nitrogen excreted as urea in the first 24 h. However, urea and not ammonia accumulated in the muscle, liver, and plasma during aerial exposure. By 48 h, the rate of urea excretion recovered fully, probably due to the greater urea concentration gradient in the kidney. It is generally accepted that an increase in carbamoyl phosphate synthetase activity is especially critical in the developmental transition from ammonotelism to ureotelism in the amphibian. Results from this study indicate that such a transition in A. mexicanum would have occurred before migration to land. Aerial exposure for 72 h exhibited no significant effect on carbamoyl phosphate synthetase-I activity or that of other OUC enzymes (with the exception of ornithine transcarbamoylase) from the liver of the juvenile A. mexicanum. This supports our hypothesis that the capacities of OUC enzymes present in the liver of the aquatic juvenile axolotl were adequate to prepare it for its invasion of the terrestrial environment. The high OUC capacity was further supported by the capability of the juvenile A. mexicanum to survive in 10 mM NH(4)Cl without accumulating amino acids in its body. The majority of the accumulating endogenous and exogenous ammonia was detoxified to urea, which led to a greater than twofold increase in urea levels in the muscle, liver, and plasma and a significant increase in urea excretion by hour 96. Hence, it can be concluded that the juvenile axolotl acquired ureotelism while submerged in water, and its hepatic capacity of urea synthesis was more than adequate to handle the toxicity of endogenous ammonia during migration to land.
Harshbarger, J.C.; Chang, S.C.; DeLanney, L.E.; Rose, F.L.; Green, D.E.
1999-01-01
Spontaneous mastocytomas studied in 18 axolotls (Ambystoma mexicanum) and six tiger salamanders (Ambystoma tigrinum) were gray-white, uni- to multilobular cutaneous protrusions from 2mm to 2cm in diameter. Tumors were moderately cellular unencapsulated masses that usually infiltrated the dermis and hypodermis with the destruction of intervening tissues. Some tumors were invading superficial bundles of the underlying skeletal muscle. Tumors consisted of mitotically active cells derived from a single lineage but showing a range of differentiation. Immature cells had nearly smooth to lightly cleft or folded basophilic nuclei bordered by a band of cytoplasm with few cytoplasmic processes and containing a few small uniform eccentric granules. Mature cells had basophilic nuclei with deep clefts or folds and abundant eosinophilic cytoplasm with multiple long intertwining cytoplasmic extensions packed with metachromatic granules. The axolotls were old individuals from an inbred laboratory colony. The tiger salamanders were wild animals from a single polluted pond. They could have been old and inbred. Both groups were neotenic. These are the first mastocytomas discovered in cold-blooded animals.
Thompson, Sierra; Muzinic, Laura; Muzinic, Christopher; Niemiller, Matthew L; Voss, S Randal
2014-06-01
Multiple factors are thought to cause limb abnormalities in amphibian populations by altering processes of limb development and regeneration. We examined adult and juvenile axolotls ( Ambystoma mexicanum ) in the Ambystoma Genetic Stock Center (AGSC) for limb and digit abnormalities to investigate the probability of normal regeneration after bite injury. We observed that 80% of larval salamanders show evidence of bite injury at the time of transition from group housing to solitary housing. Among 717 adult axolotls that were surveyed, which included solitary-housed males and group-housed females, approximately half presented abnormalities, including examples of extra or missing digits and limbs, fused digits, and digits growing from atypical anatomical positions. Bite injury likely explains these limb defects, and not abnormal development, because limbs with normal anatomy regenerated after performing rostral amputations. We infer that only 43% of AGSC larvae will present four anatomically normal looking adult limbs after incurring a bite injury. Our results show regeneration of normal limb anatomy to be less than perfect after bite injury.
OIT Times Newsletter: Volume 3, Number 1, Winter 2000
Energy Technology Data Exchange (ETDEWEB)
Sousa, L.
1999-12-16
The Winter 2000 edition of the OIT Times newsletter, a quarterly publication produced by the Office of Industrial Technologies, highlights the 1999 start-up projects, announces the OIT solicitation schedule for FY2000, and features the success of the Ohio diecasting showcase. One of the quarterly highlights was Secretary Richardson's presentation of a Certificate of Partnership to Malden Mills CEO Aaron Feuerstein at the dedication of the plant's new, advanced cogeneration system.
Page, Robert B; Voss, Stephen R; Samuels, Amy K; Smith, Jeramiah J; Putta, Srikrishna; Beachy, Christopher K
2008-02-11
Thyroid hormones (TH) induce gene expression programs that orchestrate amphibian metamorphosis. In contrast to anurans, many salamanders do not undergo metamorphosis in nature. However, they can be induced to undergo metamorphosis via exposure to thyroxine (T4). We induced metamorphosis in juvenile Mexican axolotls (Ambystoma mexicanum) using 5 and 50 nM T4, collected epidermal tissue from the head at four time points (Days 0, 2, 12, 28), and used microarray analysis to quantify mRNA abundances. Individuals reared in the higher T4 concentration initiated morphological and transcriptional changes earlier and completed metamorphosis by Day 28. In contrast, initiation of metamorphosis was delayed in the lower T4 concentration and none of the individuals completed metamorphosis by Day 28. We identified 402 genes that were statistically differentially expressed by > or = two-fold between T4 treatments at one or more non-Day 0 sampling times. To complement this analysis, we used linear and quadratic regression to identify 542 and 709 genes that were differentially expressed by > or = two-fold in the 5 and 50 nM T4 treatments, respectively. We found that T4 concentration affected the timing of gene expression and the shape of temporal gene expression profiles. However, essentially all of the identified genes were similarly affected by 5 and 50 nM T4. We discuss genes and biological processes that appear to be common to salamander and anuran metamorphosis, and also highlight clear transcriptional differences. Our results show that gene expression in axolotls is diverse and precise, and that axolotls provide new insights about amphibian metamorphosis.
Pilot trial of an age-paced parenting newsletter.
Keane, Brigid; Waterston, Tony; McConachie, Helen; Towner, Elizabeth; Cook, Margaret; Birks, Eileen
2005-10-01
Supporting parents in the first three years of a child's life has the potential to produce successful outcomes. Present government initiatives such as Sure Start focus on this age group. An American educational intervention, in the style of a monthly newsletter, was adapted for use in the UK for parents of young children. Topics were presented in an easy-to-read format and focused on infant emotional development, parent interaction and play. Newsletters, called Baby Express were posted at monthly intervals to the family home providing age-paced information which could meet the specific needs of parents at that stage of their child's life. The aim of the study was to determine the applicability of the newsletter to UK parents and evaluate their satisfaction. Sixty home-based interviews were conducted and 95 per cent of mothers reported reading all or part of the newsletter. Changes in parenting style were spontaneously reported by 28 per cent of mothers. This study found that an aged-paced parenting newsletter was an acceptable and useful method of supporting parents in the early months of a child's life and promotes positive changes in parenting behaviour.
Nuclear data newsletter. No. 42, September 2006
International Nuclear Information System (INIS)
2006-09-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and coordinated research projects and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres. Further it contains technical meetings of note of the consultants meeting on beta decay and decay heat (OECD/NEA, Paris, 2006) and a comprehensiv list of all INDC(NDS) papers published since 1968
ITER EDA newsletter. V. 6, no. 1
International Nuclear Information System (INIS)
1997-01-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter reports on the STATUS OF THE ITER EDA Overview, Design Work, ITER Physics; contains a report of the Third Technical Meeting on Quality Assurance was held at the ITER Garching Joint Work Site on 25-27 November 1996. The objectives of the meeting were to review the progress made in the Implementation of QA and to identify weal areas which require improvement. The focus was on the Large R and D Projects assigned to the EU Home Team(HT) or placed under the responsibility of the Garching JWS. 1 fig, 3 tabs
Animal production and health newsletter. No. 35
Energy Technology Data Exchange (ETDEWEB)
NONE
2001-12-01
The editorial of this issue of the Newsletter carries a strong message to its readers how the events of 11 September and the release of anthrax in the USA have affected all those involved in laboratory activities related to infectious agents. In future, it is may be needed to keep detailed records of all dangerous pathogens and account for their production, storage, and use in ways that will prevent, or at least, significantly reduce the risk of their use as bio-weapons. The rest of this issue briefly highlights FAO/IAEA consultants meeting, coordinated research programs and technical cooperation projects.
Animal production and health newsletter. No. 35
International Nuclear Information System (INIS)
2001-12-01
The editorial of this issue of the Newsletter carries a strong message to its readers how the events of 11 September and the release of anthrax in the USA have affected all those involved in laboratory activities related to infectious agents. In future, it is may be needed to keep detailed records of all dangerous pathogens and account for their production, storage, and use in ways that will prevent, or at least, significantly reduce the risk of their use as bio-weapons. The rest of this issue briefly highlights FAO/IAEA consultants meeting, coordinated research programs and technical cooperation projects
International Nuclear Information System (INIS)
2004-05-01
This issue of the SSDL Newsletter starts with a report of the first Research Co-ordination Meeting of the Co-ordinated Research Project (CRP) on the development of TLD-based quality audits for radiotherapy dosimetry in non-reference conditions. The meeting was held at the IAEA's Headquarters in Vienna during 30 September - 4 October 2002. The meeting gathered the CRP participants from Algeria, Argentina, Austria, Bulgaria, China, India, France and Poland. The second article is also a meeting's report on the development of quality assurance procedures for dosimetry calculations in radiotherapy. The meeting was held at the IAEA's Headquarters in Vienna during 13-18 October 2003. Three consultants from Austria, the Netherlands and the USA have attended the meeting and made specific recommendations to the Agency on the initiation of a CRP on Quality Assurance for dosimetry calculations in radiotherapy
DEFF Research Database (Denmark)
Lauridsen, Henrik; Foldager, Casper Bindzus; Hagensen, Mette
are generally restricted by their limited regenerative potential. Conversely, excellent animal models for regenerative studies exist in lower vertebrates such as the urodele amphibians (salamanders and newts), exemplified in the iconic Mexican axolotl (Ambystoma mexicanum) capable of regenerating whole limbs...
Shishikura, Fumio; Takeuchi, Hiro-aki; Nagai, Takatoshi
2005-11-01
Erythrocytes of the adult axolotl, Ambystoma mexicanum, have multiple hemoglobins. We separated and purified two kinds of hemoglobin, termed major hemoglobin (Hb M) and minor hemoglobin (Hb m), from a five-year-old male by hydrophobic interaction column chromatography on Alkyl Superose. The hemoglobins have two distinct alpha type globin polypeptides (alphaM and alpham) and a common beta globin polypeptide, all of which were purified in FPLC on a reversed-phase column after S-pyridylethylation. The complete amino acid sequences of the three globin chains were determined separately using nucleotide sequencing with the assistance of protein sequencing. The mature globin molecules were composed of 141 amino acid residues for alphaM globin, 143 for alpham globin and 146 for beta globin. Comparing primary structures of the five kinds of axolotl globins, including two previously established alpha type globins from the same species, with other known globins of amphibians and representatives of other vertebrates, we constructed phylogenetic trees for amphibian hemoglobins and tetrapod hemoglobins. The molecular trees indicated that alphaM, alpham, beta and the previously known alpha major globin were adult types of globins and the other known alpha globin was a larval type. The existence of two to four more globins in the axolotl erythrocyte is predicted.
International Nuclear Information System (INIS)
1995-07-01
This newsletter contains brief presentations of 6 co-ordinated research programmes and 2 training courses, and the following 3 meetings including excerpts from the reports presented: The Final Workshop of the Regional Project for Asia and the Pacific on Nuclear Techniques for the Promotion of Agroforestry Systems held at the University of Khon Kaen, Thailand, 13-17 March 1995 (10 excerpts), The Second Research Co-ordination Meeting of the FAO/IAEA CRP on the ''Use of Nuclear and Related Techniques for Evaluating the Agronomic Effectiveness of Phosphate Fertilizers, in Particular Rock Phosphates'' held in Montpellier, France, from 24-28 April 1995 (18 excerpts) and The Final FAO/IAEA Research Co-ordination Meeting on the ''Use of Nuclear and Related techniques in Assessment of Irrigation Schedules of Field crops to Increase Effective Use of Water in Irrigation Projects'' held in Rabat, Morocco, between 24-28 April 1995 (14 excerpts)
Nutritional and Health-Related Environmental Studies Newsletter, No. 04, August 2016
International Nuclear Information System (INIS)
2016-08-01
It’s time for our summer newsletter. We have started a new inter-regional project that will help better understand effects of interventions addressing stunting, and a new African regional project, elucidating long-term consequences of acute malnutrition. We are presenting new projects in the area of HIV/AIDS in Chad and on exposure to health hazards such as persistent organic pollutants and resulting health effects in Marshall Islands. You will also find updates on coordinated research activities. Links to our new outreach material and to new publications on vitamin A safety and environmental enteric dysfunction will provide you with more in-depth information.
SSDL Newsletter, No. 63, December 2014
International Nuclear Information System (INIS)
2014-12-01
This issue of the SSDL Newsletter contains two meeting reports. The first one describes the 16th Scientific Committee of the IAEA/WHO Network of Secondary Standards Dosimetry Laboratories, held at the IAEA Headquarters in March 2014. The second report is prepared from a consultants’ meeting on “Development of a Training Programme for Secondary Standards Dosimetry Laboratories”, held at the IAEA in May 2014. The next contribution is a report of a new IAEA/RCA Regional Project in Medical Physics Education and Training for the Asian region, held at the IAEA in May 2014. An overview of the new IAEA publication on “Diagnostic Radiology Physics: A Handbook for Teachers and Students” is presented in the last article
XRF newsletter. No. 6, August 2003
International Nuclear Information System (INIS)
2003-08-01
This periodical XRF Newsletter is to inform the XRF laboratories in IAEA Member States on recent developments in the field of XRF spectrometry and to exchange views on fundamental and applied aspects of sampling, sample preparation, instrumentation, quality control, etc. A few selected examples of the recent activities in the IAEA XRF Laboratory and its results in the field of XRF are presented: Application of X-ray fluorescence techniques for the determination of hazardous and essential trace elements in environmental and biological materials; X-ray fluorescence analysis and computerized tomographic imaging with a laboratory micro-beam scanning spectrometer; Data acquisition software for X-ray microprobe; XRF Laboratories Database; Collaborative Bronze Art Project
Adding Value to Customers and Developing Brands through Electronic Newsletters
Directory of Open Access Journals (Sweden)
Alexandra ZBUCHEA
2013-12-01
Full Text Available Online communication is highly efficient for contemporary business, in most market sectors. In this context, companies use several online instruments in order to achieve a wide array of objectives. Among these, online newsletters (e-newsletters are widely used, since they offer a lot of benefits for companies. Since they are flexible in terms of format and content, they are suitable to address a wide variety of publics. Therefore, e-newsletters could be not just informative (as they are widely seen, but also could add-value to customers and support branding processes and relationship development. The present paper investigated various benefits of e-newsletters in this context and highlights some rules to ensure an effective added-value e-newsletter. The research made on the e-newsletters of 5 of the leading publishing-houses in Romania shows that, at least in this market sector, this instrument is not used at its full potential. It is considered in most cases a way to stimulate sales, either directly by announcing sales, or indirectly by announcing new books releases. In some cases news on events and on the activity of the publishing-houses are presenting, leading to image development.
Directory of Open Access Journals (Sweden)
Samuels Amy K
2008-02-01
Full Text Available Abstract Background Thyroid hormones (TH induce gene expression programs that orchestrate amphibian metamorphosis. In contrast to anurans, many salamanders do not undergo metamorphosis in nature. However, they can be induced to undergo metamorphosis via exposure to thyroxine (T4. We induced metamorphosis in juvenile Mexican axolotls (Ambystoma mexicanum using 5 and 50 nM T4, collected epidermal tissue from the head at four time points (Days 0, 2, 12, 28, and used microarray analysis to quantify mRNA abundances. Results Individuals reared in the higher T4 concentration initiated morphological and transcriptional changes earlier and completed metamorphosis by Day 28. In contrast, initiation of metamorphosis was delayed in the lower T4 concentration and none of the individuals completed metamorphosis by Day 28. We identified 402 genes that were statistically differentially expressed by ≥ two-fold between T4 treatments at one or more non-Day 0 sampling times. To complement this analysis, we used linear and quadratic regression to identify 542 and 709 genes that were differentially expressed by ≥ two-fold in the 5 and 50 nM T4 treatments, respectively. Conclusion We found that T4 concentration affected the timing of gene expression and the shape of temporal gene expression profiles. However, essentially all of the identified genes were similarly affected by 5 and 50 nM T4. We discuss genes and biological processes that appear to be common to salamander and anuran metamorphosis, and also highlight clear transcriptional differences. Our results show that gene expression in axolotls is diverse and precise, and that axolotls provide new insights about amphibian metamorphosis.
Evaluation of a public health newsletter intended for travel agents.
Provost, Sylvie
2003-01-01
Travel agents are in a key position to encourage travelers to seek consultation in travel clinics. Since the beginning of the year 2000, a newsletter specifically designed to sensitize travel agents to travel health has been published by the public health authorities and distributed to all travel agencies in Quebec. This study was undertaken to evaluate the utilization and appreciation of the newsletter by travel agents and its impact on preventive practices. During the autumn of 2001, a cross-sectional descriptive survey was carried out among travel agencies in Quebec. Data were collected using a self-administered questionnaire sent by fax with a postal follow-up. A total of 252 of the 950 travel agencies contacted (27%) answered our questionnaire. In all, 78% of respondents said their agency receives the newsletter. Among these agencies, the majority of respondents considered that the subjects discussed in the newsletter are interesting (often or in general: 96%), that the subjects and preventive recommendations for travel destinations are useful in the travel agent's practice (often or in general: 89%), and generally presented in an adequate way (96%). According to the respondents, the newsletter encouraged them, often or very often, to inform travelers about travel-related health problems (70%) or to recommend a consultation in a travel clinic (63%). The impact of the newsletter on the recommendation to consult was greater among agents having more than 10 years' experience (odds ratio [OR] 3.2). When asked about the best way to send them the newsletter, only 31% identified bulk mailing, which was the current mode of distribution. Satisfaction rate with the newsletter appears to be high among respondents who receive it. However, the low response rate to the survey may indicate that as a whole, the travel agents' interest in the newsletter is mitigated. Despite the limitations of this study, the results will allow us to modify some aspects of the publication
Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl
Zhu, Wei; Pao, Gerald M; Satoh, Akira; Cummings, Gillian; Monaghan, James R; Harkins, Timothy T; Bryant, Susan V; Voss, S Randal; Gardiner, David M; Hunter, Tony
2012-01-01
The capacity for tissue and organ regeneration in humans is dwarfed by comparison to that of salamanders. Emerging evidence suggests that mechanisms learned from the early phase of salamander limb regeneration-wound healing, cellular dedifferentiation and blastemal formation-will reveal therapeutic approaches for tissue regeneration in humans. Here we describe a unique transcriptional fingerprint of regenerating limb tissue in the Mexican axolotl (Ambystoma mexicanum) that is indicative of ce...
Directory of Open Access Journals (Sweden)
Susana Chávez-Silverman
2012-11-01
Full Text Available In this crónica, I pay homage (and talk back to! one of my favourite authors, Julio Cortázar, who I had the great privilege and pleasure of befriending in 1980, when he was a visiting professor at UC-Berkeley. I have been obsessed with time-travel, doubling, and interstitiality since I was very young; even the most casual Cortázar reader (if such a thing is possible will immediately recognise these as recurrent themes in his work. Here, faced with several actual axolotl in a Buenos Aires aquarium, I explore and comment on Cortázar’s strangely mesmerising meditation on identity and transformation. My personal connection is (as in much of my writing concerned with aspects of gender and sexuality suppressed or (more likely ignored in Cortázar’s version. I identify, too, with a poignant in-betweenness and ambiguity I read in the figure of the axolotl—and in the work of Cortázar and Alejandra Pizarnik.
Animal Production and Health Newsletter, No. 64, July 2016
International Nuclear Information System (INIS)
2016-07-01
Looking back at the activities of the past six months, we had several emergency actions and consultations (e.g. support to MS to address the Zika virus outbreaks in Latin America and the lumpy skin disease outbreaks in Eastern Europe), workshops, training courses, RCMs and consultants meetings. Activities scheduled for the next half-year include project review meetings, RCMs, interregional training courses and regional workshops. Both past and future activities are discussed in further detail in this newsletter and are also accessible at our website
Energy Technology Data Exchange (ETDEWEB)
2011-03-01
This quarterly newsletter provides timely news and information about the plans and progress of the Energy Development in Island Nations U.S. Virgin Islands pilot project, including significant events and milestones, work undertaken by each of the five working groups, and project-related renewable energy and energy efficiency projects.
Animal Production and Health Newsletter, No. 54, July 2011
International Nuclear Information System (INIS)
2011-07-01
It is with great enthusiasm that I address you in a new era - the era of a rinderpest free world. The OIE and FAO have declared the world-wide eradication of Rinderpest recently - but more about this later. The first part of this year has been a busy time for all personnel in the subprogramme. Apart from our regular Coordinated Research Project (CRP) activities and our technical support given to national and regional Technical Cooperation projects (TC), we were involved in the technical planning of projects for the new TC projects by Member States for the 2012/2013 biennial project cycle. We were also occupied with finalizing the IAEA's 2012/2013 Work and Budget Programme. It is hoped that our inputs will serve the best interests of our Member States. Please look at our web site and our Animal Production and Health Newsletter to familiarize yourselves with all the activities of the subprogramme
Carlson, Bruce M.
1972-01-01
Rotation of a skin cuff 180° around the proximodistal axis of the upper arm in the axolotl results in the formation of multiple regenerates in about 80° of cases after amputation of the limb through the rotated skin. Rotation of the dermis or the flexor and extensor muscles folowed by amputation
Program on Public Conceptions of Science, Newsletter 9.
Blanpied, William A., Ed.; Holton, Gerald, Ed.
This newsletter is divided into six sections: an introduction; general news items and communications; news items and communications in ethical and human values areas; supplement to Newsletter 8, Section II; an essay; and a bibliography classifying material as to subject emphasis in the area of human values and ethics. The essay is entitled "A…
Clarkson, Pamela M; Beachy, Christopher K
2015-12-01
We tested the hypothesis that salamanders growing at different rates would have allocation patterns that differ among male and female metamorphic and larval salamanders. We raised individual axolotls, Ambystoma mexicanum , on four food regimes: constant high growth (throughout the experiment), constant low growth (restricted throughout the experiment), high growth switched to low growth (ad libitum switched after 140 d to restricted), and low growth switched to high growth (restricted switched after 140 d to ad libitum). Because axolotls are obligate paedomorphs, we exposed half of the salamanders to thyroid hormone to induce metamorphosis. We assayed growth and dissected and weighed gonads and fat bodies. Salamanders that were switched from restricted to ad libitum food regime delayed metamorphosis. In all treatment groups, females had larger gonads than males and males had larger fat bodies than females. The association between storage and reproduction differed between larvae and metamorphs and depended on sex.
Plant breeding and genetics newsletter. No. 13
International Nuclear Information System (INIS)
2004-06-01
This issue reports on the creation of the Agency's Subprogramme of Sustainable Intensification of Crop Production Systems (E1) through the merger of the Soils and Plant Breeding and Genetics Subprogrammes together with part of the Entomology Subprogramme activities. Implementation of a new Coordinated Research Project (CRP) on the Effects of Mutagenic Agents on the DNA Sequence in Plants, and the successful submission of a new CRP proposal on Pyramiding of Mutated Genes Contributing to Crop Quality and Resistance to Stress Affecting Quality were among the major activities of our Subprogramme during the last six months. We actively participated in the International Year of Rice (IYR 2004) events such as the Meeting of the Informal International Working Group on the International Year of Rice (IIWG) and the FAO Rice Conference on Rice in Global Markets and Sustainable Production Systems (Rome, Italy), both in February this year. A lot of work has been concentrated this last semester on the preparation of Programme and Budget for the biennium 2006-2007 and the appraisal of TC proposals for the biennium 2005-2006. The Mutation Breeding Newsletter and the Mutation Breeding Review will merge to become the Mutation Breeding Newsletter and Reviews (MBN and R). Starting at the end of July, the MBN and R will appear on a regular basis
Plant breeding and genetics newsletter. No. 2
International Nuclear Information System (INIS)
1998-12-01
This is the second issue of the Plant Breeding and Genetics Newsletter. The Newsletter will inform you about current activities of the FAO/IAEA sub-programme on plant breeding and genetics which is implemented by the Plant Breeding and Genetics Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture (Vienna) in close collaboration with the Plant Breeding Unit of the FAO/IAEA Agriculture and Biotechnology Laboratory (Seibersdorf)
Plant breeding and genetics newsletter. No. 1
International Nuclear Information System (INIS)
1998-05-01
This is the first issue of the Plant Breeding and Genetics Newsletter. The Newsletter will inform you about current activities of the FAO/IAEA sub-programme on plant breeding and genetics which is implemented by the Plant Breeding and Genetics Section of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture (Vienna) in close collaboration with the Plant Breeding Unit of the FAO/IAEA Agriculture and Biotechnology Laboratory (Seibersdorf)
Animal production and health newsletter. No. 20
International Nuclear Information System (INIS)
1994-07-01
The activities of the Animal Production and Health Section of the Joint FAO/IAEA Division are carried out through the operation of Co-ordinated Research Programmes and Technical Co-operation projects, both of which aim to encourage and improve the capacity of national institutions in tropical and subtropical countries to identify and resolve problems connected with livestock development. This particular programme at the outset, it was envisaged that an inter-disciplinary approach would be adopted by each participating institute whereby studies on nutrition, reproduction and health would be integrated into a number of site specific projects. The one discussed in this newsletter covers animal production and focussing on animal reproduction and reproduction-nutrition interactions. This paper contains an outline for the program which encourages scientists from universities and research institutes to provide assistance and solutions to developing countries on the technical difficulties associated with artificial insemination
SSDL Newsletter, No. 66, June 2017
International Nuclear Information System (INIS)
2017-06-01
This issue of the SSDL Newsletter (No. 66) is the first one published only in electronic form. This change in format will open new possibilities by allowing us to use more interactive materials in the future. We would like also to increase the interaction between the members of the IAEA/WHO SSDL Network and thus invite all members to send new ideas and articles for the Newsletter. One of our services is to organize comparisons for members of the IAEA/WHO SSDL Network. We provide comparison services for standards used for radiation therapy, diagnostic radiology and radiation protection calibrations. To be able to provide these services, we also have to take part in comparisons to support our calibration and measurement capabilities. The first article of this newsletter is one example of this kind of comparison and provides comparison results of the radiation therapy level standards of the National Research Council of Canada (NRC) and the IAEA. In this newsletter, we have included several reports from different meetings and courses. The article starting from page 9 provides a comprehensive information package for countries establishing and developing dosimetry audit centres. The article that follows introduces a new publication in progress for establishing an SSDL. Training courses about radiation protection calibrations and preparing a quality management system for SSDLs were both organized under IAEA technical cooperation. The uncertainty workshop organised in April by DMRP had more than 80 participants and, in addition to the guidance on uncertainty estimations, it provided the participants a good opportunity to meet other dosimetry experts
Mutation breeding newsletter. No. 43
International Nuclear Information System (INIS)
1997-10-01
This issue of the Newsletter includes articles dealing with radiation induced mutation based plant breeding research findings aimed at improving productivity, disease resistance and tolerance of stress conditions
ITER EDA newsletter. V. 4, no. 11
International Nuclear Information System (INIS)
1995-11-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter contains a report on the Ninth Meeting of the ITER Management Advisory Committee held in St. Petersburg, Russia, on November 3, 1995; a report on the Seventh International Conference on Fusion Reactor Materials held at Obninsk, Russia, 25-29 September, 1995; on the presentation of the ITER Project during a symposium on fusion energy held at Champaign, Illinois, USA, October 1-5, 1995; and on two meetings on ITER diagnostics, i.e., an international workshop on diagnostics for ITER held in Varenna, Italy, 28 August - 1 September, 1995; followed by the Third Diagnostics Expert Group Workshop held September 4-5 in the same location
DEFF Research Database (Denmark)
Haugan, Birgitte M; Halberg, Kenneth Agerlin; Jespersen, Åse
2010-01-01
whether the duct is involved in urine modification using larvae of the freshwater amphibian Ambystoma mexicanum (axolotl) as model. Results We investigated structural as well as physiological properties of the pronephric duct. The key elements of our methodology were: using histology, light...
Energy Technology Data Exchange (ETDEWEB)
2003-04-01
This newsletter provides a brief overview of the Field Verification Project for Small Wind Turbines conducted at the NWTC and a description of current activities. The newsletter also contains case studies of current projects.
Mutation breeding newsletter. No. 20
Energy Technology Data Exchange (ETDEWEB)
NONE
1982-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 17
Energy Technology Data Exchange (ETDEWEB)
NONE
1981-03-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 16
Energy Technology Data Exchange (ETDEWEB)
NONE
1980-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 8
Energy Technology Data Exchange (ETDEWEB)
NONE
1976-09-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 12
Energy Technology Data Exchange (ETDEWEB)
NONE
1978-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 10
Energy Technology Data Exchange (ETDEWEB)
NONE
1977-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 32
Energy Technology Data Exchange (ETDEWEB)
NONE
1988-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 18
Energy Technology Data Exchange (ETDEWEB)
NONE
1981-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 9
Energy Technology Data Exchange (ETDEWEB)
NONE
1977-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 22
Energy Technology Data Exchange (ETDEWEB)
NONE
1983-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 15
Energy Technology Data Exchange (ETDEWEB)
NONE
1980-02-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 9
International Nuclear Information System (INIS)
1977-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 32
International Nuclear Information System (INIS)
1988-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 15
International Nuclear Information System (INIS)
1980-02-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 14
International Nuclear Information System (INIS)
1979-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 16
International Nuclear Information System (INIS)
1980-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 12
International Nuclear Information System (INIS)
1978-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 17
International Nuclear Information System (INIS)
1981-03-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 30
International Nuclear Information System (INIS)
1987-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 18
International Nuclear Information System (INIS)
1981-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 10
International Nuclear Information System (INIS)
1977-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 8
International Nuclear Information System (INIS)
1976-09-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 11
Energy Technology Data Exchange (ETDEWEB)
NONE
1978-02-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 31
Energy Technology Data Exchange (ETDEWEB)
NONE
1988-03-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 31
International Nuclear Information System (INIS)
1988-03-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 11
International Nuclear Information System (INIS)
1978-02-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 20
International Nuclear Information System (INIS)
1982-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 19
International Nuclear Information System (INIS)
1982-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 13
Energy Technology Data Exchange (ETDEWEB)
NONE
1979-02-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 30
Energy Technology Data Exchange (ETDEWEB)
NONE
1987-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 19
Energy Technology Data Exchange (ETDEWEB)
NONE
1982-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 23
Energy Technology Data Exchange (ETDEWEB)
NONE
1983-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 14
Energy Technology Data Exchange (ETDEWEB)
NONE
1979-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 23
International Nuclear Information System (INIS)
1983-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 13
International Nuclear Information System (INIS)
1979-02-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 22
International Nuclear Information System (INIS)
1983-07-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Animal production and health newsletter. No. 41
International Nuclear Information System (INIS)
2004-12-01
In the June 2004 Newsletter, we focused on the topic of molecular diagnostic technologies and the way forward. It is clear from the feedback, that there is a strong desire for having reliable, definitive, sensitive, specific, cost effective and on-site diagnostic tests, in parallel with so-called herd or population surveillance tests. This will allow for the implementation of more effective disease control strategies. It is indeed exciting to consider the current technological explosion and its consequences and what potential advantages might be in store for many of our Member States. This will also help to ensure that we keep abreast of new developments and employ the most appropriate tools.The conclusions and recommendations will be placed on the web as soon as they are available and published in the next Newsletter. The second topic under discussion in this Newsletter will focus on the management of animal genetic resources. Both past and future activities are described in further detail in this issue
SSDL Newsletter, No. 59, April 2011
International Nuclear Information System (INIS)
2011-04-01
The first article of this issue of the SSDL Newsletter is a report of the 14th SSDL Scientific Committee (SSC) Meeting held at the IAEA Headquarters in March 2010. The second article is a report of the Coordinated Research Project (CRP E2.10.06) on the Implementation of the International Code of Practice on Dosimetry in Diagnostic Radiology (TRS-457). The third article is a progress report of an international working group jointly established by the IAEA and AAPM on Small and Composite Field Dosimetry. The fourth article briefly describes the purpose and content of a new web site called IAEA Human Health Campus (http://humanhealth.iaea.org). A short note of the IDOS conference held at IAEA Headquarters in Vienna during November 2010 is given in the last article
Nutritional and Health-Related Environmental Studies Newsletter, No. 01, January 2015
International Nuclear Information System (INIS)
2015-01-01
It is with great excitement we welcome you to the first edition of the NAHRES E-Newsletter. We intend to issue an E-Newsletter several times per year to share information about our latest projects, events, publications and more. Adequate nutrition is a fundamental cornerstone of development. The burden of malnutrition hinders the advancement of individuals, communities and countries and a concerted effort is needed to combat malnutrition in all its forms. The Nutritional and Health-Related Environmental Studies section of the IAEA complements the efforts of other UN agencies and NGO’s by supporting the use of nuclear techniques to understand changes in body composition following an intervention, and how the body is using the nutrients in the food we eat. This information helps nutrition policymakers decide what interventions will be most effective to reduce malnutrition. This mandate resonates with Article II of the IAEA's Statute: ''The Agency shall seek to accelerate and enlarge the contribution of atomic energy to peace, health and prosperity throughout the world.''Nuclear techniques add value by improving the specificity and sensitivity of nutritional evaluations such as the assessment of body composition, total daily energy expenditure, intake of human milk in breastfed infants, vitamin A status, and bioavailability of micronutrients from foods. The IAEA has promoted extensive use of these techniques in Member States through supporting national and regional nutrition projects via the Technical Cooperation Program and through Coordinated Research Projects addressing priority areas in nutrition.
Energy Technology Data Exchange (ETDEWEB)
Turska, R.
1975-01-01
The data available up to now concerning the structure of Golgi complex in different types of normal and pathologically changed cells are very divergent. Results are reported from detailed studies on changes occurring within the Golgi complex in the spleen of three-month old axolotls after x-ray irradiation with a single dose of 1,200 R and killed by decapitation 15, 30, 60 minutes and 3, 6, and 12 hours after irradiation.
Mutation breeding newsletter. No. 28
International Nuclear Information System (INIS)
1986-09-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 24
Energy Technology Data Exchange (ETDEWEB)
NONE
1984-07-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 25
International Nuclear Information System (INIS)
1985-01-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 28
Energy Technology Data Exchange (ETDEWEB)
NONE
1986-09-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 26
International Nuclear Information System (INIS)
1985-10-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 27
International Nuclear Information System (INIS)
1986-02-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Nuclear data newsletter. No. 31
International Nuclear Information System (INIS)
2001-03-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue includes announcement of new data libraries, and gives citations for various current nuclear data publications
Mutation breeding newsletter. No. 24
International Nuclear Information System (INIS)
1984-07-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 26
Energy Technology Data Exchange (ETDEWEB)
NONE
1985-10-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 25
Energy Technology Data Exchange (ETDEWEB)
NONE
1985-01-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 27
Energy Technology Data Exchange (ETDEWEB)
NONE
1986-02-01
This issue of the Newsletter presents reports and research abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Resegmentation in the Mexican axolotl, Ambystoma mexicanum.
Piekarski, Nadine; Olsson, Lennart
2014-02-01
The segmental series of somites in the vertebrate embryo gives rise to the axial skeleton. In amniote models, single vertebrae are derived from the sclerotome of two adjacent somites. This process, known as resegmentation, is well-studied using the quail-chick chimeric system, but the presumed generality of resegmentation across vertebrates remains poorly evaluated. Resegmentation has been questioned in anamniotes, given that the sclerotome is much smaller and lacks obvious differentiation between cranial and caudal portions. Here, we provide the first experimental evidence that resegmentation does occur in a species of amphibian. Fate mapping of individual somites in the Mexican axolotl (Ambystoma mexicanum) revealed that individual vertebrae receive cells from two adjacent somites as in the chicken. These findings suggest that large size and segmentation of the sclerotome into distinct cranial and caudal portions are not requirements for resegmentation. Our results, in addition to those for zebrafish, indicate that resegmentation is a general process in building the vertebral column in vertebrates, although it may be achieved in different ways in different groups. Copyright © 2013 Wiley Periodicals, Inc.
Mutation breeding newsletter. No. 4
Energy Technology Data Exchange (ETDEWEB)
NONE
1974-08-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 6
Energy Technology Data Exchange (ETDEWEB)
NONE
1975-08-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 5
Energy Technology Data Exchange (ETDEWEB)
NONE
1975-02-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 3
International Nuclear Information System (INIS)
1974-01-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 3
Energy Technology Data Exchange (ETDEWEB)
NONE
1974-01-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 29
Energy Technology Data Exchange (ETDEWEB)
NONE
1987-02-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 4
International Nuclear Information System (INIS)
1974-08-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 7
Energy Technology Data Exchange (ETDEWEB)
NONE
1976-01-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 44
International Nuclear Information System (INIS)
1999-04-01
This issue of the Newsletter presents research reports on the role of radiation induced mutation and chemical mutagens in improving productivity, disease resistance; cold and salinity tolerance of various crops and ornamental plants
Mutation breeding newsletter. No. 1
Energy Technology Data Exchange (ETDEWEB)
NONE
1972-05-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Mutation breeding newsletter. No. 29
International Nuclear Information System (INIS)
1987-02-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 5
International Nuclear Information System (INIS)
1975-02-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 2
International Nuclear Information System (INIS)
1973-02-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 1
International Nuclear Information System (INIS)
1972-05-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 6
International Nuclear Information System (INIS)
1975-08-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 7
International Nuclear Information System (INIS)
1976-01-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. No. 2
Energy Technology Data Exchange (ETDEWEB)
NONE
1973-02-01
This issue of the Newsletter presents reports and rea search abstracts on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
New England Wind Forum: A Wind Powering America Project, Volume 1, Issue 4 -- May 2008 (Newsletter)
Energy Technology Data Exchange (ETDEWEB)
Grace, R. C.; Gifford, J.
2008-05-01
The New England Wind Forum electronic newsletter summarizes the latest news in wind energy development activity, markets, education, and policy in the New England region. It also features an interview with a key figure influencing New England's wind energy development. Volume 1, Issue 4 features an interview with Brian Fairbank, president and CEO of Jiminy Peak Mountain Resort.
Energy Technology Data Exchange (ETDEWEB)
Grace, R. C.; Gifford, J.
2007-10-01
The New England Wind Forum electronic newsletter summarizes the latest news in wind energy development activity, markets, education, and policy in the New England region. It also features an interview with a key figure influencing New England's wind energy development. Volume 1, Issue 3 features an interview with Andrew Dzykewicz, Commissioner of the Rhode Island Office of Energy Resources.
International Nuclear Information System (INIS)
Conil-Lacoste, J.F.
2006-07-01
This newsletter no 39 of Powernext provides statistical data on Powernext day-Ahead from june 2005 to june 2006, prices and volume of Powernext Futures from june 2004 to june 2006, powernext carbon from june 2005 to june 2006 and some news on Powernext. (A.L.B.)
Energy Technology Data Exchange (ETDEWEB)
2002-04-01
This newsletter provides a brief overview of the Field Verification Project for Small Wind Turbines conducted out of the NWTC and a description of current activities. The newsletter also contains case studies of current projects.
International Nuclear Information System (INIS)
1987-03-01
The new Uranium Newsletter is presented as an IAEA annual newsletter. The organization of the IAEA and its involvement with uranium since its founding in 1957 is described. The ''Red Book'' (Uranium Resources, Production and Demand) is mentioned. The Technical Assistance Programme of the IAEA in this field is also briefly mentioned. The contents also include information on the following meetings: The Technical Committee Meeting on Uranium Deposits in Magmatic and Metamorphic Rocks, Advisory Group Meeting on the Use of Airborne Radiometric Data, and the Technical Committee Meeting on Metallogenesis. Recent publications are listed. Current research contracts in uranium exploration are mentioned. IAEA publications on uranium (in press) are listed also. Country reports from the following countries are included: Australia, Brazil, Canada, China (People's Republic of), Denmark, Finland, Germany (Federal Republic of), Malaysia, Philippines, Portugal, South Africa (Republic of), Spain, Syrian Arab Republic, United Kingdom, United States of America, Zambia, and Greece. There is also a report from the Commission of European Communities
Phan, Anne Quy
2014-01-01
Salamanders are unique among adult vertebrates in their ability to regenerate complex body structures after traumatic injury. Axolotl limb regeneration is a stepwise sequence of three requisite processes: (1) scarless wound healing to generate a regenerative wound epithelium, (2) blastema formation by migration, proliferation and dedifferentiation to create a mass of multipotent regeneration-competent progenitor cells, and (3) induction of pattern formation by interaction of cells with opposi...
International Nuclear Information System (INIS)
2001-01-01
The first article of this issue of the SSDL Newsletter is the report of the 9th SSDL Scientific Committee Meeting held from 13-17 November 2000. The editor wishes to draw the readers' attention to recommendations xviii, xxi and xxvi of the Scientific Committee, to evaluate the potential needs of SSDLs for the audit and calibration services in diagnostic radiology, brachytherapy and nuclear medicine metrology. For that purpose, the Secretariat of the IAEA/WHO network is preparing a survey form to be sent to all SSDLs of the network. It is hoped that the network members will fill in the questionnaire and return it to the Secretariat as soon as possible. The second article is a technical note prepared by the staff of the Dosimetry and Medical Radiation Physics Section that deals with the ''effect of humidity on measurements with a well type chamber''. Those SSDL members possessing a well type chamber are encouraged to conduct similar frequent constancy checks and submit their contributions to the editor for publication in a forthcoming issue of the Newsletter. Contributions will be duly acknowledged. The third article is a report of the Second Research Co-ordination Meeting (RCM) for the Co-ordinated Research Project (CRP E2.40.07) on ''the development of a quality assurance programme for radiation therapy dosimetry in developing countries'', held at IAEA Headquarters from 4-8 December 2000. The aim of the CRP is to establish national Quality Assurance (QA) networks for external quality audits for radiotherapy hospitals in developing countries. This is done by setting up national External Audit Groups (EAGs) with laboratory backup for operating TLD audits for radiotherapy dosimetry. The main results achieved under this CRP are included in the report. A new SSDL has recently joined our Network: the Laboratory of State Dosimetry Standards of the Belarussian State Institute of Metrology (Gosstandart). The SSDL has been added to the database of the IAEA/WHO Network of
ITER EDA Newsletter. V.2, no.6
International Nuclear Information System (INIS)
1993-06-01
This issue of the newsletter on the Engineering Design Activities for the ITER Project includes (i) a status report on these activities describing the development of the design and design parameters, the research and development program, the joint central team, and the joint work sites; (ii) a description of the In-Vessel Ancillaries Division (consisting of the RF Heating and Current Drive Group and the In-Vessel Diagnostics Group) including its organizational chart and priorities of activities; (iii) a report on the Technical Meeting on Design Standards and Remote Handling held at the San Diego Co-Centre from May 24-28, 1993; (iv) and a report on a Technical Committee Meeting on Plasma Equilibrium and Control held at the Naka Co-Centre on April 26-29, 1993
ITER EDA newsletter. V. 5, no.1
International Nuclear Information System (INIS)
1996-01-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter contains reports on the RF-Based ITER JCT (Joint Central Team) Support Design Team (by N. Kornev), the third international workshop on plasma disruptions (by Dr. A. Hassanein and Dr. V. Litunovski) held at Obninsk, Russia, September 28-29, 1995, and the IAEA Advisory Group Meeting on Completion of Fendl-1 and the start of Fendl-2 (by Dr. A.B. Pashchenko); the Fendl library is a comprehensive collection of high-quality nuclear data, selected from the various existing national data libraries, covering the necessary nuclear input data for all physics and engineering aspects of the material development, design, operation, and safety of the ITER project in its current EDA phase
International Nuclear Information System (INIS)
1988-12-01
This issue of the newsletter presents a report of the third meeting of the SSDL Scientific Committee. Articles on ''Absorbed dose determination in photon and electron beams'' and ''Comparison of absorbed dose determinations using the IAEA dosimetry protocol and the ferrous sulphate dosimeter'' are the major topics covered
Jarial, M S; Wilkins, J H
2003-10-01
The ultrastructure of the external gill epithelium of the axolotl, Ambystoma mexicanum, has been examined using conventional transmission electron microscopy to elucidate its role in ionic transport. Four cell types are identified in the gill filament and primary gill bar epithelium. These are granular, ciliated, Leydig and basal cells. A fifth cell type, the flat mitochondria-rich cell is only found in the gill bar epithelium. The predominant granular cells display microvilli at their surface and their cytoplasm contains abundant mitochondria, rough endoplasmic reticulum, Golgi complexes, vesicles and PAS+ secretory granules that are extruded at the surface, which along with secretions from the Leydig cells form a mucous coat. The granular cells are joined apically by junctional complexes consisting of zonulae occludens, zonulae adherens and desmosomes. The lateral membranes of granular cells enclose large intercellular spaces that are closed at the apical ends but remain open at the basal ends adjoining capillaries. In AgNO3-treated axolotl, the gills become darkly stained, the silver grains penetrate apical membranes and appear in the cytoplasm, accumulating near the lateral membranes and also enter the intercellular spaces. These findings are consistent with the dual role of the gill epithelium in mucus production and active ionic transport.
ITER ITA newsletter No. 32, July 2006
International Nuclear Information System (INIS)
2006-07-01
This issue of ITER ITA (ITER transitional Arrangements) newsletter contains concise information about ITER related activities. The ITER Parties, at their Ministerial Meeting in May 2006 in Brussels, initialled the draft text of the prospective Agreement on the Establishment of the ITER International Fusion Energy Organization for the Joint Implementation of the ITER Project as well as the draft text of the Agreement on the Privileges and Immunities of the ITER International Fusion Energy Organisation for the Joint Implementation of the ITER Project. The Parties have requested that the IAEA Director General serve as Depositary of the two aforementioned Agreements and that the IAEA establish a Trust Fund to Support Common Expenditures under the ITER Transitional Arrangements, pending entry into force of the prospective Agreement on the Establishment of the ITER International Fusion Energy Organization for the Joint Implementation of the ITER Project. At its June Meeting in Vienna, the IAEA Board of Governors approved these requests. There is also information about the Tenth Meeting of the International Tokamak Physics Activity (ITPA) Topical Group (TG) on Diagnostics was held at the Kurchatov Institute, Moscow, from 10-14 April 2006
Networking and Information Technology Research and Development, Executive Office of the President — Welcome to this first issue of NITRD Leads IT, a quarterly newsletter of the Networking and Information Technology Research and Development (NITRD) Program. We...
NITRD NewsLetter - October 2016
Networking and Information Technology Research and Development, Executive Office of the President — Welcome to the second issue of NITRD Leads IT, a quarterly newsletter of the Networking and Information Technology Research and Development (NITRD) Program. I...
International Nuclear Information System (INIS)
1995-07-01
The newsletter presents report of the sixth meeting of the SSDL Scientific Committee held in Vienna in March 1995. Major issues discussed include programmes and activities of the Dosimetry Section, statistical data on the SSDL network and IAEA activities on high-dose measurements. It also present uncertainty of the calibration factor
Energy Technology Data Exchange (ETDEWEB)
NONE
1995-07-01
The newsletter presents report of the sixth meeting of the SSDL Scientific Committee held in Vienna in March 1995. Major issues discussed include programmes and activities of the Dosimetry Section, statistical data on the SSDL network and IAEA activities on high-dose measurements. It also present uncertainty of the calibration factor.
NITRD NewsLetter - October 2017
Networking and Information Technology Research and Development, Executive Office of the President — Welcome to the October 2017 issue of the NITRD Leads IT quarterly newsletter of the Networking and Information Technology Research and Development Program. When we...
Early regulation of axolotl limb regeneration.
Makanae, Aki; Satoh, Akira
2012-10-01
Amphibian limb regeneration has been studied for a long time. In amphibian limb regeneration, an undifferentiated blastema is formed around the region damaged by amputation. The induction process of blastema formation has remained largely unknown because it is difficult to study the induction of limb regeneration. The recently developed accessory limb model (ALM) allows the investigation of limb induction and reveals early events of amphibian limb regeneration. The interaction between nerves and wound epidermis/epithelium is an important aspect of limb regeneration. During early limb regeneration, neurotrophic factors act on wound epithelium, leading to development of a functional epidermis/epithelium called the apical epithelial cap (AEC). AEC and nerves create a specific environment that inhibits wound healing and induces regeneration through blastema formation. It is suggested that FGF-signaling and MMP activities participate in creating a regenerative environment. To understand why urodele amphibians can create such a regenerative environment and humans cannot, it is necessary to identify the similarities and differences between regenerative and nonregenerative animals. Here we focus on ALM to consider limb regeneration from a new perspective and we also reported that focal adhesion kinase (FAK)-Src signaling controlled fibroblasts migration in axolotl limb regeneration. Copyright © 2012 Wiley Periodicals, Inc.
SSDL newsletter No. 52, July 2006
International Nuclear Information System (INIS)
2006-08-01
This issue of the SSDL Newsletter contains the report of the 12th SSDL Scientific Committee (SSC) Meeting held at the IAEA Headquarters from 7-10 March 2006. The SSC conducts biennial reviews and evaluations of the Dosimetry and Medical Radiation Physics activities. Following each meeting, the report of the SSC is addressed to the Directors General of the IAEA and WHO and circulated subsequently to Member States through this Newsletter. The report is pending acceptance by the IAEA and WHO. The second article is a brief note on the polarity of electrometers. The IAEA has received many queries from SSDLs on the definitions used by manufacturers of ionization chambers concerning the sign of the polarity of the chamberelectrometer connecting systems. The lack of clarity has also induced mistakes in some dosimetry comparison exercises where inconsistent polarities were used by some participants. It is hoped that this note will help clarify the issue. The readers were informed in the SSDL Newsletter No. 51 on the extension of the calibration facilities at Seibersdorf. It is a pleasure to announce that less than one year later, the construction of the new wing was completed. The inauguration ceremony was held on June 1 2006
Mutation breeding newsletter. No. 45
International Nuclear Information System (INIS)
2001-07-01
This issue of the Mutation Breeding newsletter contains 39 articles dealing with radiation induced mutations and chemical mutagenesis techniques in plant breeding programs with the aims of improving crop productivity and disease resistance as well as exploring genetic variabilities
Mutation Breeding Newsletter. No. 37
International Nuclear Information System (INIS)
1991-01-01
This newsletter contains a brief account of FAO/IAEA meetings held in 1990 on plant breeding involving the use of induced mutations. It also features a list of commercially available plant cultivars produced by such techniques. Refs and tabs
Antarctic Meteorite Newsletter
Lindstrom, Marilyn
2000-01-01
This newsletter contains something for everyone! It lists classifications of about 440 meteorites mostly from the 1997 and 1998 ANSMET (Antarctic Search for Meteorites) seasons. It also gives descriptions of about 45 meteorites of special petrologic type. These include 1 iron, 17 chondrites (7 CC, 1 EC, 9 OC) and 27 achondrites (25 HED, UR). Most notable are an acapoloite (GRA98028) and an olivine diogenite (GRA98108).
DEFF Research Database (Denmark)
Lauridsen, Henrik; Kjær, N.B.; Bek, Maria
oxide particles (VSOP) in animal cells enable non invasive cell tracking using magnetic resonance imaging (MRI) and can prove useful, when visualising regenerative processes. This study examines the possibility of labelling limited numbers of axolotl blastema cells (aBC) and pig endothelial progenitor...... implanted in live axolotl tail and dead porcine heart, respectively. Cellular iron uptake was determined using inductively coupled plasma optical emission spectrometry (ICP-OES). Results: T2*-weighted 2D gradient-echo sequences on samples of 10˄5 cells yielded at significant linear correlations between...
Publishing a Newsletter for Education Associations. PR Bookshelf No. 5.
National Education Association, Washington, DC.
This handbook for how to publish a newsletter for educational associations is divided into ten short sections. The sections discuss such topics as analyzing the audience, the makeup of the editorial board, what should go into a newsletter, ways to get the news, aids for the editor, writing simply and clearly, planning layout, printing, following…
Nutritional and Health-Related Environmental Studies Newsletter, No. 02, August 2015
International Nuclear Information System (INIS)
2015-08-01
Here we are with our second edition of the NAHRES E-Newsletter. We hope you will enjoy our update – since our first edition we have been busy with a number of interesting meetings, new research projects, eLearning modules and the preparation of a technical meeting for October 2015 on how living in unsanitary conditions affects intestinal integrity and nutrient absorption. Two interlaboratory studies are currently being conducted by NAHRES – one on analysis of deuterium enrichment and the other one on the analysis of doubly labelled water.
Kühn, Eduard R; De Groef, Bert; Grommen, Sylvia V H; Van der Geyten, Serge; Darras, Veerle M
2004-06-01
Entanglement of functions between the adrenal (or interrenal) and thyroid axis has been well described for all vertebrates and can be tracked down up to the level of gene expression. Both thyroid hormones and corticosteroids may induce morphological changes leading to metamorphosis climax in the neotenic Mexican axolotl (Ambystoma mexicanum). In a first series of experiments, metamorphosis was induced with an injection of 25 microg T(4) on three alternate days as judged by a decrease in body weight and tail height together with complete gill resorption. This injection also resulted in elevated plasma concentrations of T(3) and corticosterone. Previous results have indicated that the same dose of dexamethasone (DEX) is ineffective in this regard (Gen. Comp. Endocrinol. 127 (2002) 157). In a second series of experiments low doses of T(4) (0.5 microg) or DEX (5 microg) were ineffective to induce morphological changes. However, when these submetamorphic doses were injected together, morphological changes were observed within one week leading to complete metamorphosis. It is concluded that thyroid hormones combined with corticosteroids are essential for metamorphosis in the axolotl and that only high doses of either thyroid hormone or corticosteroid can induce morphological changes when injected separately.
Food Irradiation Newsletter. V. 12, no. 1
International Nuclear Information System (INIS)
1988-04-01
This Newsletter reports summaries of work carried out in the past year. A coordinated research programme on ''Use of Irradiation to Control Infectivity of Food-borne Parasites'' was implemented in early 1987. The first Research Coordination Meeting of this programme was held in Poznan, Poland, August 1987 and its report is included. Another important development is ''Food Irradiation Plant: Project Profile'' of the International Finance Corporation (IFC), a subsidiary of the World Bank. IFC is in principle ready to finance installations on food irradiation facilities in developing countries provided that the proposals are submitted through Governmental channels. Details on developing such proposals for possible funding by IFC are included. This issue also contains a supplement, an up-dated list of clearance of irradiated foods. Refs, 1 fig., 1 tab
Nuclear Data Newsletter, No. 62, January 2017
International Nuclear Information System (INIS)
2017-01-01
For many of us, THE nuclear data event of 2016 was the International Conference on Nuclear Data for Science and Technology in Bruges. A short report is available in this issue of the Nuclear Data Newsletter. During the summer, our Section organized a final Technical Meeting of the Data Development Project on Neutron Standards, which are going to be essential for the next release of various world nuclear data libraries, and a Consultancy Meeting on maintenance and improvement of the Fusion Evaluated Nuclear Data Library (FENDL). A relatively new activity is the Meeting on R-matrix codes development, which was held for the second consecutive year, in December 2016. It was interesting to see the development of new R-matrix codes, both from the neutron evaluation community and other fields such as astrophysics.
Nuclear Data Newsletter. No. 24
International Nuclear Information System (INIS)
1997-12-01
This issue of the nuclear data newsletter gives information on the following topics: staff changes in the Data Center, new data libraries, charts of nuclides, conference announcement, data indexes and bibliographies, Nuclear Data Center coordination, nuclear data standards and some nuclear data
Vladimirova, I G; Kleĭmenov, S Iu; Alekseeva, T A; Radzinskaia, L I
2003-01-01
Concordant changes in the rate of energy metabolism and specific growth rate of axolotls have been revealed. Several periods of ontogeny are distinguished, which differ in the ratio of energy metabolism to body weight and, therefore, are described by different allometric equations. It is suggested that the specific growth rate of an animal determines the type of dependence of energy metabolism on body weight.
Denz, Christopher R; Zhang, Chi; Jia, Pingping; Du, Jianfeng; Huang, Xupei; Dube, Syamalima; Thomas, Anish; Poiesz, Bernard J; Dube, Dipak K
2011-09-01
Tropomyosins are a family of actin-binding proteins that show cell-specific diversity by a combination of multiple genes and alternative RNA splicing. Of the 4 different tropomyosin genes, TPM4 plays a pivotal role in myofibrillogenesis as well as cardiac contractility in amphibians. In this study, we amplified and sequenced the upstream regulatory region of the TPM4 gene from both normal and mutant axolotl hearts. To identify the cis-elements that are essential for the expression of the TPM4, we created various deletion mutants of the TPM4 promoter DNA, inserted the deleted segments into PGL3 vector, and performed promoter-reporter assay using luciferase as the reporter gene. Comparison of sequences of the promoter region of the TPM4 gene from normal and mutant axolotl revealed no mutations in the promoter sequence of the mutant TPM4 gene. CArG box elements that are generally involved in controlling the expression of several other muscle-specific gene promoters were not found in the upstream regulatory region of the TPM4 gene. In deletion experiments, loss of activity of the reporter gene was noted upon deletion which was then restored upon further deletion suggesting the presence of both positive and negative cis-elements in the upstream regulatory region of the TPM4 gene. We believe that this is the first axolotl promoter that has ever been cloned and studied with clear evidence that it functions in mammalian cell lines. Although striated muscle-specific cis-acting elements are absent from the promoter region of TPM4 gene, our results suggest the presence of positive and negative cis-elements in the promoter region, which in conjunction with positive and negative trans-elements may be involved in regulating the expression of TPM4 gene in a tissue-specific manner.
Nuclear Information Newsletter. No. 17, October 2015. 45th INIS Anniversary Newsletter
International Nuclear Information System (INIS)
2015-10-01
This year marks the 45th anniversary since the creation of INIS. INIS has come a long way since the IAEA Board of Governors approved the International Nuclear Information System in 1969. Officially, INIS started operations in January 1970, but it wasn’t until May 1970 that its first product, the INIS Atomindex, was issued. This date is considered the ‘birth’ of INIS. This special issue of the Nuclear Information Newsletter is devoted to the first forty-five years of INIS. INIS was designed as an international cooperative venture, requiring the active participation of its members, who, over the years, compiled a remarkable collection consisting of more than 3.8 million bibliographic records, making it one of the world's largest collections of published information on the peaceful uses of nuclear science and technology. This spirit of international cooperation is reflected in this issue of the Newsletter. Articles written by many INIS Members, as well as former and current INIS Secretariat staff, bring to light some of the known, and hidden, moments in the history of INIS. Put together, these articles shed light on some of those treasured moments that made INIS what it is today
International Nuclear Information System (INIS)
2002-05-01
This ITER CTA newsletter contains information about the Third Negotiations Meeting on the Joint Implementation of ITER held in Moscow on 23-24 April 2002 and about the visit of Canadian officials and members of the Canadian delegation to RF research center 'Kurchatov Institute'
Nuclear data newsletter. No. 19
International Nuclear Information System (INIS)
1994-09-01
This issue of the Nuclear Data Newsletter dated September 1994 contains information on the following topics: WRENDA 93/94, online nuclear data service, data indexes and bibliographies, new nuclear data libraries received, a list of publications on nuclear data libraries grouped by type and field
Mutation breeding newsletter. No. 40
International Nuclear Information System (INIS)
1993-01-01
This newsletter contains an obituary to Iosif Abramovitch Rapoport and an outline of three new co-ordinated research programmes as well as a number of short contributed articles concerning the development and testing of mutant plant lines. These contributed articles have been indexed separately
Nuclear data newsletter. No. 19
Energy Technology Data Exchange (ETDEWEB)
NONE
1994-09-01
This issue of the Nuclear Data Newsletter dated September 1994 contains information on the following topics: WRENDA 93/94, online nuclear data service, data indexes and bibliographies, new nuclear data libraries received, a list of publications on nuclear data libraries grouped by type and field.
Nuclear data newsletter. No. 18
Energy Technology Data Exchange (ETDEWEB)
NONE
1993-11-01
This issue of the Nuclear Data Newsletter dated November 1993 gives information on the following topics: data indexes and bibliographies, new nuclear data libraries received including a package of three data libraries on photon-electron interaction, a list of selected new publications on nuclear data.
Nuclear data newsletter. No. 18
International Nuclear Information System (INIS)
1993-11-01
This issue of the Nuclear Data Newsletter dated November 1993 gives information on the following topics: data indexes and bibliographies, new nuclear data libraries received including a package of three data libraries on photon-electron interaction, a list of selected new publications on nuclear data
Pathological features of olfactory neuroblastoma in an axolotl (Ambystoma mexicanum).
Shioda, Chieko; Uchida, Kazuyuki; Nakayama, Hiroyuki
2011-08-01
A one-year-old, female Mexican axolotl (Ambystoma mexicanum) had a rough-surfaced, polypoid, pink tumor mass of approximately 10 mm in diameter in the oral cavity. Histologically, the tumor extended from the ethmoturbinate region and into the oral cavity and had replaced some of the maxillary bone tissue. The tumor mass was composed of a lobular architecture of small round-shaped tumor cells with occasional Flexner-Wintersteiner-like rosette formation. There were no metastatic lesions in the other organs. Immunohistochemically, the tumor cells were partly positive for several neural markers (class III beta-tubulin, S-100 protein, and doublecortin) and intensely positive for an epithelial marker (cytokeratin AE1/AE3). These results suggest that the present tumor originated from neuroectodermal tissue. Considering the location and histological and immunohistochemical features of the tumor, a diagnosis of olfactory neuroblastoma was made.
Lineage tracing of genome-edited alleles reveals high fidelity axolotl limb regeneration.
Flowers, Grant Parker; Sanor, Lucas D; Crews, Craig M
2017-09-16
Salamanders are unparalleled among tetrapods in their ability to regenerate many structures, including entire limbs, and the study of this ability may provide insights into human regenerative therapies. The complex structure of the limb poses challenges to the investigation of the cellular and molecular basis of its regeneration. Using CRISPR/Cas, we genetically labelled unique cell lineages within the developing axolotl embryo and tracked the frequency of each lineage within amputated and fully regenerated limbs. This allowed us, for the first time, to assess the contributions of multiple low frequency cell lineages to the regenerating limb at once. Our comparisons reveal that regenerated limbs are high fidelity replicas of the originals even after repeated amputations.
McCusker, Catherine; Bryant, Susan V.
2015-01-01
Abstract The axolotl is one of the few tetrapods that are capable of regenerating complicated biological structures, such as complete limbs, throughout adulthood. Upon injury the axolotl generates a population of regeneration‐competent limb progenitor cells known as the blastema, which will grow, establish pattern, and differentiate into the missing limb structures. In this review we focus on the crucial early events that occur during wound healing, the neural−epithelial interactions that drive the formation of the early blastema, and how these mechanisms differ from those of other species that have restricted regenerative potential, such as humans. We also discuss how the presence of cells from the different axes of the limb is required for the continued growth and establishment of pattern in the blastema as described in the polar coordinate model, and how this positional information is reprogrammed in blastema cells during regeneration. Multiple cell types from the mature limb stump contribute to the blastema at different stages of regeneration, and we discuss the contribution of these types to the regenerate with reference to whether they are “pattern‐forming” or “pattern‐following” cells. Lastly, we explain how an engineering approach will help resolve unanswered questions in limb regeneration, with the goal of translating these concepts to developing better human regenerative therapies. PMID:27499868
Metamorfosis: La animalidad y el mito en La Metamorfosis de Kafka y Axolotl de Cortázar
Directory of Open Access Journals (Sweden)
Catalina Villalobos Díaz
2017-07-01
Full Text Available El presente artículo propone una lectura de la animalidad, principalmente de la metamorfosis, por medio de dos relatos de dos grandes escritores de la literatura: Axolotl, de Julio Cortázar, y La Metamorfosis, de Franz Kafka. A través de estos textos, se plantea un análisis con respecto a lo que representa una transformación y el mito tras la metamorfosis como tal.
Sefton, Elizabeth M; Piekarski, Nadine; Hanken, James
2015-01-01
The impressive morphological diversification of vertebrates was achieved in part by innovation and modification of the pharyngeal skeleton. Extensive fate mapping in amniote models has revealed a primarily cranial neural crest derivation of the pharyngeal skeleton. Although comparable fate maps of amphibians produced over several decades have failed to document a neural crest derivation of ventromedial elements in these vertebrates, a recent report provides evidence of a mesodermal origin of one of these elements, basibranchial 2, in the axolotl. We used a transgenic labeling protocol and grafts of labeled cells between GFP+ and white embryos to derive a fate map that describes contributions of both cranial neural crest and mesoderm to the axolotl pharyngeal skeleton, and we conducted additional experiments that probe the mechanisms that underlie mesodermal patterning. Our fate map confirms a dual embryonic origin of the pharyngeal skeleton in urodeles, including derivation of basibranchial 2 from mesoderm closely associated with the second heart field. Additionally, heterotopic transplantation experiments reveal lineage restriction of mesodermal cells that contribute to pharyngeal cartilage. The mesoderm-derived component of the pharyngeal skeleton appears to be particularly sensitive to retinoic acid (RA): administration of exogenous RA leads to loss of the second basibranchial, but not the first. Neural crest was undoubtedly critical in the evolution of the vertebrate pharyngeal skeleton, but mesoderm may have played a central role in forming ventromedial elements, in particular. When and how many times during vertebrate phylogeny a mesodermal contribution to the pharyngeal skeleton evolved remain to be resolved. © 2015 Wiley Periodicals, Inc.
Mansour, N; Lahnsteiner, F; Patzner, R A
2011-01-15
This study established the first protocol for collection of gametes from live axolotl, Ambystoma mexicanum, by gentle abdominal massage and in vitro fertilization. To stimulate spermiation and ovulation, human chorionic gonadotrophin (hCG) and Ovopel pellets, which are commercially used to stimulate spawning in fish, were tested. The hCG was more effective than Ovopel pellets and yielded a higher semen volume in the injected males and a shorter response time in the females. Collected semen by this method was already motile and fertile. Fertile eggs could be collected in 3-4 successive collection times after the female has started the typical spawning behaviour. The fertilization condition that yielded the highest hatching rate was mixing semen with eggs before the addition of a fertilization saline solution (20 mmol/l NaCl, 1 mmol/l KCl, 1 mmol/l Mg(2)SO(4), 1 mmol Ca(2)Cl, 3 mmol NaHCO(3), 10 mmol/l Tris, pH 8.5 - Osmolality = 65 mosmol/kg). When the pH of the fertilization solution was increased to ≥ 10, the hatching rate was significantly increased. The use of fertilization solutions with osmolalities of ≥ 150 and ≥ 182 were accompanied with a significant decrease in hatching rates and the appearance of deformed larvae, respectively. In conclusion, a reliable protocol for gamete collection from live axolotl is established as a laboratory model of in vitro fertilization for urodele amphibians. This protocol may be transferable to endangered urodeles. Copyright © 2011 Elsevier Inc. All rights reserved.
IEC Newsletter, No. 53/3 (2015)
International Nuclear Information System (INIS)
2015-12-01
The IEC Newsletter is prepared by the Incident and Emergency Centre (IEC), Department of Nuclear Safety and Security of the IAEA. The Incident and Emergency Centre (IEC) is the global focal point for emergency preparedness and response for nuclear and radiological safety or security related incidents, emergencies, threats or events of media interest. The IEC is also the world’s centre for coordination of international assistance in emergency. The following topics are presented in this newsletter: Prepared to Respond International Conference on Global EPR; Launch of EPRIMS; First meeting of EPR Standards Committee; IEC and French experts test assessment and prognosis arrangements; IEC and Swiss counterparts conduct an assessment and prognosis drill; Consultancy on CANDUspecific EALs; Regional Workshops; Recently reported events; Member State preparedness; IEC welcomes young visitors on Bring Your Children to Work day
International Nuclear Information System (INIS)
Torres, Carlos
1999-04-01
This newsletter summarises the progress made by its three Working Groups (Scenario Generation and Justification; Modelling and Data; and Confidence Building), three Safety Case Groups (Vault; Radon-type facility; and Borehole Safety Case Groups) and ISAM Virtual Workspace Group during the second RCM along with plans for future work. The document also provides a list of currently available ISAM documents
International Nuclear Information System (INIS)
1992-12-01
This newsletter contains a report of the Fifth Meeting of the SSDL Scientific Committee, held in Vienna in November 1992. Also included are two articles about a quality assurance network for radiotherapy dosimetry, a report on IAEA activities on high-dose measurements and a Status Report on Technical Report Series No. 277. These items have been indexed separately. Refs, figs and tabs
Proliferation zones in the axolotl brain and regeneration of the telencephalon
Directory of Open Access Journals (Sweden)
Maden Malcolm
2013-01-01
Full Text Available Abstract Background Although the brains of lower vertebrates are known to exhibit somewhat limited regeneration after incisional or stab wounds, the Urodele brain exhibits extensive regeneration after massive tissue removal. Discovering whether and how neural progenitor cells that reside in the ventricular zones of Urodeles proliferate to mediate tissue repair in response to injury may produce novel leads for regenerative strategies. Here we show that endogenous neural progenitor cells resident to the ventricular zone of Urodeles spontaneously proliferate, producing progeny that migrate throughout the telencephalon before terminally differentiating into neurons. These progenitor cells appear to be responsible for telencephalon regeneration after tissue removal and their activity may be up-regulated by injury through an olfactory cue. Results There is extensive proliferation of endogenous neural progenitor cells throughout the ventricular zone of the adult axolotl brain. The highest levels are observed in the telencephalon, especially the dorsolateral aspect, and cerebellum. Lower levels are observed in the mesencephalon and rhombencephalon. New cells produced in the ventricular zone migrate laterally, dorsally and ventrally into the surrounding neuronal layer. After migrating from the ventricular zone, the new cells primarily express markers of neuronal differentiative fates. Large-scale telencephalic tissue removal stimulates progenitor cell proliferation in the ventricular zone of the damaged region, followed by proliferation in the tissue that surrounds the healing edges of the wound until the telencephalon has completed regeneration. The proliferative stimulus appears to reside in the olfactory system, because telencephalic regeneration does not occur in the brains of olfactory bulbectomized animals in which the damaged neural tissue simply heals over. Conclusion There is a continual generation of neuronal cells from neural progenitor cells
TASCC newsletter volume 6 no. 6
International Nuclear Information System (INIS)
Thomson, L.
1992-06-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this June issue is a report on operator training, operating record and facility report and a listing of experiments conducted in June
TASCC newsletter volume 6 no. 11
International Nuclear Information System (INIS)
Thomson, L.
1992-01-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this issue is a report on Canadians at the Eurogam spectrometer, cyclotron beam report, facility report and operating record, a listing of experiments conducted
TASCC newsletter volume 9 no. 6
International Nuclear Information System (INIS)
Thomson, L.
1995-06-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this June issue of TASCC is an update of the facility, TASCC workshop on international success and a listing of Junes's experiments. 1 fig
Soils newsletter. V. 19, no. 1
International Nuclear Information System (INIS)
1996-07-01
The Newsletter announces meetings, training programs and short communications on coordinated research programs in soil fertility and crop production. The training courses mainly deal with application of nuclear techniques in nitrogen fixation and efficient use of fertilizers
TASCC newsletter volume 5 no. 5
International Nuclear Information System (INIS)
Thomson, L.
1991-05-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this May issue is information on a workshop for material science studies, a facility report and operating record and the experiments conducted. 1 fig
Soils newsletter. V. 19, no. 2
International Nuclear Information System (INIS)
1996-12-01
The Newsletter announces meetings, training programs and short communications on coordinated research programs in soil fertility and crop production. The training courses mainly deal with application of nuclear techniques in nitrogen fixation and efficient use of fertilizers
Soils newsletter. V. 19, no. 2
Energy Technology Data Exchange (ETDEWEB)
NONE
1996-12-01
The Newsletter announces meetings, training programs and short communications on coordinated research programs in soil fertility and crop production. The training courses mainly deal with application of nuclear techniques in nitrogen fixation and efficient use of fertilizers.
Lamers, W. H.; Vink, C.; Charles, R.
1978-01-01
1. In axolotl liver, the activity of carbamoyl-phosphate synthase (ammonia), expressed per mg liver protein, decreases to a minimum at 5 months of age, then increases to a maximum at 8 months of age which is followed by a decrease again. The initial decrease between 3 and 5 months of age appears to
Soils Newsletter. V. 12, no. 2
International Nuclear Information System (INIS)
1989-12-01
This Newsletter includes reports of four research co-ordination meetings: on isotopic studies on nitrogen fixation and nitrogen cycling by blue-green algae and Azolla (final meeting, September 1989, IAEA, Vienna); on isotopic studies on increasing and stabilizing plant productivity in low phosphate and semi-arid and sub-humid soils of the tropics and sub-tropics (first meeting, October 1989, IAEA, Vienna); on the evaluation and calibration of nuclear techniques compared with traditional methods in soil water studies (July 1989, IAEA, Vienna); and on the use of isotopes in studies to improve the yield and nitrogen fixation of the common bean in Latin America (April 1989, Irapuato, Mexico). A new co-ordinated research programme on the use of nuclear and related techniques in the assessment of irrigation schedules of field crops to increase the effective use of water in irrigation projects is announced, and some of the technical co-operation programmes in the Latin America Region are briefly described. 2 tabs
Chen, Xiaoping; Song, Fengyu; Jhamb, Deepali; Li, Jiliang; Bottino, Marco C.; Palakal, Mathew J.; Stocum, David L.
2015-01-01
We tested the ability of the axolotl (Ambystoma mexicanum) fibula to regenerate across segment defects of different size in the absence of intervention or after implant of a unique 8-braid pig small intestine submucosa (SIS) scaffold, with or without incorporated growth factor combinations or tissue protein extract. Fractures and defects of 10% and 20% of the total limb length regenerated well without any intervention, but 40% and 50% defects failed to regenerate after either simple removal of bone or implanting SIS scaffold alone. By contrast, scaffold soaked in the growth factor combination BMP-4/HGF or in protein extract of intact limb tissue promoted partial or extensive induction of cartilage and bone across 50% segment defects in 30%-33% of cases. These results show that BMP-4/HGF and intact tissue protein extract can promote the events required to induce cartilage and bone formation across a segment defect larger than critical size and that the long bones of axolotl limbs are an inexpensive model to screen soluble factors and natural and synthetic scaffolds for their efficacy in stimulating this process. PMID:26098852
Nuclear data newsletter. No. 16
International Nuclear Information System (INIS)
1992-01-01
This issue of the Nuclear Data Newsletter dated November 1991, gives information on the following topics: Data indexes and bibliographies nuclear data computer codes, new data libraries, selected new publication on nuclear data, numeric data bases all related to the activity of the Nuclear Data Section (NDS) of the IAEA
TASCC newsletter volume 9 no. 6
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1995-06-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this June issue of TASCC is an update of the facility, TASCC workshop on international success and a listing of Junes`s experiments. 1 fig.
Nuclear data newsletter. No. 30
International Nuclear Information System (INIS)
2000-09-01
Issue No. 30 of the Nuclear Data Newsletter gives information about the following: new data libraries available at the IAEA (photonuclear data library, charged-particle cross section database for medical radioisotope production); updated databases and libraries; computer codes and packages; list of selected reports and documents; and co-operating nuclear data service centres
TASCC newsletter volume 8 no. 7
International Nuclear Information System (INIS)
Thomson, L.
1994-07-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this July issue of TASCC is an update of the facility,news on TASCC personnel, results of a coulomb-excitation and a listing of July's experiments. 4 figs
Nuclear Data Newsletter. Issue No. 15
International Nuclear Information System (INIS)
1991-03-01
This issue of the Nuclear Data Newsletter (March 1991) gives information on the following topics: Data indexes and bibliographies, new data libraries received, selected new publications on nuclear data, related to the activity of the Nuclear Data Section of the IAEA
TASCC newsletter volume 9 no. 12
International Nuclear Information System (INIS)
Thomson, L.
1995-12-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this December issued of TASCC is an update of the facility, a year -end review of TASCC by the director and a listing of December's experiments. 1 fig
Animal production and health newsletter. No. 26
International Nuclear Information System (INIS)
1997-06-01
This issue of the newsletter highlights coordinated research programs in animal diseases including ELISA and RIA techniques in reproductive studies. Announcement of staff changes and forthcoming events are also covered
Animal production and health newsletter. No. 26
Energy Technology Data Exchange (ETDEWEB)
NONE
1997-06-01
This issue of the newsletter highlights coordinated research programs in animal diseases including ELISA and RIA techniques in reproductive studies. Announcement of staff changes and forthcoming events are also covered.
Nuclear power newsletter Vol. 2, no. 3
International Nuclear Information System (INIS)
2005-09-01
The topics presented in this newsletter are: factors contributing to increased nuclear electricity production for the period 1990-2004 ; NPP operating performance and life cycle management; improving human performance quality and technical infrastructure; and technology development and applications for advanced reactors. Three factors contributing the electricity production increase are analysed and presented - growth due to new power plants building (36%); existing NPP uprating (7%); and energy availability improvements (57%). Trends of installed capacity and available production are given. The newsletter also presents technical issues that influence decisions on operation and nuclear power infrastructure and delayed NPPs. In the last article technology advances are presented in details for water cooled reactors, fast reactors and accelerator driven systems, gas cooled reactors and desalination plants
Plant breeding and genetics newsletter. No. 11
International Nuclear Information System (INIS)
2003-07-01
Implementation of a new CRP on Physical mapping technologies for the identification and characterization of mutated genes contributing to crop quality, organization of mutant germplasm database and repository, implementation of new TC projects and activation of work on molecular characterization of Musa putative germplasm as well as sequencing of BAC clones were the major activities of our sub-Programme on Plant Breeding and Genetics during the last six months. A lot of work has been concentrated on organizing a mutant germplasm repository. The first collections of rice and linseed mutants have already arrived and their descriptions have been introduced into the mutated germplasm database. We found this activity especially important to stimulate exchange of crop germplasm among plant breeders. Similarly there is an urgent need to collect mutants of various crops as necessary material for functional genomics and germplasm enhancement. Nevertheless, many crop research institutes are initiating large-scale mutation programmes with the use of their own plant material. To help them in selecting the mutagen, doses and mutation treatment procedure, we published the third issue of Mutation Breeding Newsletter Index of No. 21-44. The Index is also available through our website http://www.iaea.org/programmes/nafa/d2/index.html. The numerous requests for issues of the Mutation Breeding Newsletter already received from various countries indicate the value of this 80-page index for plant breeders and research institutes. We were invited to present the activities, achievements and trends of our sub-Programme at two very important, international meetings: The International Conference on the Status of Plant and Animal Genome Research, known as the Plant and Animal Genome (PAG XI), and The International Congress on 'In the Wake of the Double Helix - From the Green Revolution to the Gene Revolution'. At this last meeting, an initiative was taken to organize the Crop Root Research
Plant breeding and genetics newsletter. No. 10
International Nuclear Information System (INIS)
2003-01-01
The most important event related to the activity of the Plant Breeding and Genetics sub-programme in the past six months was the 2nd FAO/IAEA Interregional Training Course on 'Mutant Germplasm Characterization using Molecular Markers' which was held at Seibersdorf, 4-29 November 2002. In addition to basic molecular and marker techniques, which were also a subject of the first training course last year, fluorescence in situ hybridisation methods were included in the teaching and demonstration programme. As we informed you in the last edition of this Newsletter, a laboratory manual was published with detailed protocols on molecular markers techniques entitled 'Mutant germplasm characterization using molecular markers. A Manual'. (IAEA Training Course Series No. 19). (available for free distribution under conditions provided on page 11 of this Newsletter). We have also finished editing a book on 'Doubled haploid production in crop plants. A Manual.' This book was prepared in close collaboration with EU COST 851 activities. Ken Kasha (Canada), Brian Forster (UK) and lwona Szarejko (Poland) helped to edit more than 40 protocols for doubled haploid production in at least 23 crop species. The preparation of this manual reflects our our interest in the development and application of this technology for crop improvement. Two CRPs and numerous Technical Co-operation projects greatly contributed to the development of doubled haploid methods and also to implementation of this technology in crop improvement programmes of many countries. Numerous other important activities have been undertaken by the Plant Breeding and Genetics sub-programme during the last 6 months. A consultants meeting on 'Low cost technology in plant tissue culture' was held in Vienna and its results will be summarized in the form of an IAEA-TECDOC which is now in the final stage of preparation. In addition to the implementation of five Co-ordinated Research Projects, nine workshops and national or regional
International Nuclear Information System (INIS)
1995-12-01
This issue of the SSDL newsletter contains recommendations on the use and dissemination of SSDLs of N D,W factors; these should not be transferred to hospital ionization chambers or used by SSDLs for calibration of therapy beams until a new code of Practice, replacing TRS-277, becomes available. Description of the on-going and planned activities of the IAEA Dosimetry Section is also presented. Refs, figs, tabs
Animal production and health newsletter. No. 23
Energy Technology Data Exchange (ETDEWEB)
NONE
1996-01-01
The Newsletter presents the staffing, past and forthcoming workshops, status of the existing coordinated research programmes in the area of application of nuclear and biotechnology techniques in animal production and health.
Animal production and health newsletter. No. 23
International Nuclear Information System (INIS)
1996-01-01
The Newsletter presents the staffing, past and forthcoming workshops, status of the existing coordinated research programmes in the area of application of nuclear and biotechnology techniques in animal production and health
International Nuclear Information System (INIS)
2002-01-01
This ITER CTA Newsletter issue comprises information about the following ITER Meetings: The second negotiation meeting on the joint implementation of ITER, held in Tokyo(Japan) on 22-23 January 2002, and an international ITER symposium on burning plasma science and technology, held the day later after the second negotiation meeting at the same place
TASCC newsletter volume 8 no. 4
International Nuclear Information System (INIS)
Thomson, L.
1994-04-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this April issue of TASCC is an update of the facility, news on the Penning-trap spectrometer, educators at CRL, AECB inspection and a listing of April's experiments. 1 fig
TASCC newsletter volume 7 no. 12
International Nuclear Information System (INIS)
Thomson, L.
1993-12-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this December issue of TASCC is an update of the facility, a year end review by the director and a listing of experiments carried out in December. 3 figs
TASCC newsletter volume 9 no. 8
International Nuclear Information System (INIS)
Thomson, L.
1995-08-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this August issue of TASCC is an update of the facility, improvement in memory effects by the AMS at TASCC, personnel news and a listing of August's experiments. 3 figs
Soils Newsletter. V. 11, no. 2
International Nuclear Information System (INIS)
1988-12-01
This Newsletter contains a report of the second research co-ordination meeting on nuclear techniques to improve crop production on salt-affected soils (October 1988, IAEA, Vienna) and lists some of the technical co-operation programmes in Europe and the Middle East
TASCC newsletter volume 7 no. 11
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1993-11-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this November issue of TASCC is an update of the facility, news of a purchase of phase-shifters and a listing of experiments run in November. 2 figs.
TASCC newsletter volume 7 no. 12
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1993-12-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this December issue of TASCC is an update of the facility, a year end review by the director and a listing of experiments carried out in December. 3 figs.
TASCC newsletter volume 8 no. 7
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1994-07-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this July issue of TASCC is an update of the facility,news on TASCC personnel, results of a coulomb-excitation and a listing of July`s experiments. 4 figs.
TASCC newsletter volume 9 no. 4
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1995-04-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this April issue of TASCC is an update of the facility, analysis of Chernobyl samples, staff changes, Internet availability and a listing of April`s experiments. 1 fig.
TASCC newsletter volume 9 no. 12
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1995-12-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this December issued of TASCC is an update of the facility, a year -end review of TASCC by the director and a listing of December`s experiments. 1 fig.
Nuclear data newsletter, No. 46, September 2008
International Nuclear Information System (INIS)
2008-09-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and database news concerning nuclear data libraries, computer codes and coordinated research projects and lists selected charts, reports and documents on nuclear data. Further it contains meeting reports of the Biennial Meeting of the International Nuclear Data Committee, 22-25 April 2008, IAEA Headquarters, Vienna, Austria; the Joint ICTP-IAEA Advanced Workshop on Model Codes for Spallation Reactions, 4-8 February 2008, ICTP, Trieste, Italy; the Workshop on Nuclear Structure and Decay Data: Theory and Evaluation, 28 April ? 9 May 2008, ICTP Trieste, Italy; the Joint ICTP-IAEA Workshop on Nuclear Reaction Data for Advanced Reactor Technologies, 19-30 May 2008, ICTP, Trieste, Italy and the Consultants Meeting on High-precision Beta-intensity Measurements and Evaluations for Specific PET Radioisotopes, 3-5 September 2008, IAEA, Vienna, Austria
Nuclear data newsletter, No. 47, May 2009
International Nuclear Information System (INIS)
2009-05-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and database news concerning nuclear data libraries, computer codes and coordinated research projects and lists selected charts, reports and documents on nuclear data. Further it contains meeting reports of the IAEA Consultants Meeting on Total Absorption Gamma-ray Spectroscopy (TAGS) - Current Status of Measurement Programmes for Decay Heat Calculations and Other Applications, 27 - 28 January 2009, the Workshop on Modelling and Evaluating Nuclear Reaction Data for Transport Calculations, 15-19 December 2008, the Reference Data Libraries for Nuclear Applications - ENSDF, 10-11 November 2008, the Consultants Meeting on International Neutron Cross-Section Standards: Measurements and Evaluation Techniques, 13-15 October 2008 and the Technical Meeting of the International Network of Nuclear Reaction Data Centres, IPPE, Obninsk, and Moscow State University, Moscow, Russian Federation, 22-25 September 2008
ITER EDA newsletter. V. 8, no. 3
International Nuclear Information System (INIS)
1999-03-01
This newsletter contains reports on: 'The ITER management advisory committee (MAC) meeting in Cadarache' and on 'ITER technical advisory committee meeting at Garching'. It contains photos of the participants of both meetings
Animal production and health newsletter. No. 24
International Nuclear Information System (INIS)
1996-07-01
The Newsletter announces meetings and training programs in animal husbandry and animal health related activities undertaken by the IAEA. Short communications on coordinated research programs in animal production and health are included
Animal production and health newsletter. No. 24
Energy Technology Data Exchange (ETDEWEB)
NONE
1996-07-01
The Newsletter announces meetings and training programs in animal husbandry and animal health related activities undertaken by the IAEA. Short communications on coordinated research programs in animal production and health are included.
ITER EDA newsletter. V. 6, no. 12
International Nuclear Information System (INIS)
1997-12-01
This issue of the ITER Newsletter contains summary reports (i) on the Sixth ITER Technical Meeting on Safety and Environment and (ii) on JAERI's Annual Public Seminar on Fusion Research and Development
SSDL Newsletter, No. 67, December 2017
International Nuclear Information System (INIS)
2017-12-01
This issue of the SSDL Newsletter (No. 67) is a special issue dedicated to the IAEA/WHO SSDL Network. The SSDL Network was established in 1976 and its main aim is to support Member States to maintain the traceability of their dose measurements. The first article of this newsletter is a historical review of the SSDL Network. The SSDL Charter explains the privileges, rights and duties of the Network members and it was originally drawn up and published in 1999. The original SSDL Charter has now been reviewed and updated and electronic version of the 2nd edition is available on our website. The second article of this Newsletter is the foreword of the new Charter. It describes the new edition of the Charter and explains how the requirements for the Network members have changed. One of the requirements of a full SSDL Network member is to fill out and submit the annual report form. This data has been gathered from 2015 and 2016 annual reports and a summary is given in the third article. The article gives a statistical overview of the services provided by the SSDL Network members. In the future, we would like to share this data with you. We are creating a new database called Dosimetry Laboratory Network i.e. DOLNET. The preliminary version of this database is currently available on our new website. However, we are currently working on revising and upgrading it to be able to provide more information about the services available at the SSDLs of the IAEA/WHO SSDL Network.
Harvard Project Physics Newsletter 10. The Project Physics Course, Text.
Harvard Univ., Cambridge, MA. Harvard Project Physics.
A short description of the availability of Harvard Project Physics course components is given as is a discussion of the growth of the use of Project Physics in schools, including some enrollment data and survey results. Locations of the 1970 and 1971 Summer Institutes are listed. Adaptations of Project Physics course outside the United States are…
Fuel cycle and waste newsletter. Vol. 3, No. 1, April 2007
International Nuclear Information System (INIS)
2007-04-01
This issue of the Fuel Cycle and Waste Newsletter reports on the international conference on lessons learned from the decommissioning of nuclear facilities and the safe termination of nuclear activities. It discusses the next steps related to the Net-Enabled Waste Management DataBase (NEWMDB) and informs about BOSS (BOrehole disposal of Sealed radioactive Sources), and about predisposal activities in 20067. Furthermore it includes a peer review of the Romanian project for low and intermediate waste disposal - WATRP mission. It stresses the need for research reactor coalitions and centres of excellence and lists a workplan for this initiative, including the complementary Technical Coordination project RER/4/029. The development of inert matrix fuels (IMF) for reducing plutonium stock-piles is discussed, as well as power reactor engineering and spent fuel repackaging preparations at the Vinca institute. Relevant meetings and recent publications are listed
TASCC newsletter volume 6 no. 9
International Nuclear Information System (INIS)
Thomson, L.
1992-09-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this September issue is a report of TASCC productivity, awards from AECL, and a symposium hosted by TASCC, a facility report and operating record and a listing of September's experiments. 1 fig
TASCC newsletter volume 8 no. 4
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1994-04-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this April issue of TASCC is an update of the facility, news on the Penning-trap spectrometer, educators at CRL, AECB inspection and a listing of April`s experiments. 1 fig.
Disarmament. Newsletter. V. 11, no. 1
International Nuclear Information System (INIS)
1993-01-01
The newsletter presents materials covering the following subjects: signing of START 2 treaty by Russia and the United States; arms regulation and disarmament in the post-cold war area; accession of new countries to the Non-Proliferation Treaty; trends towards fewer nuclear-weapon tests
International Nuclear Information System (INIS)
2002-09-01
This second issue, you cannot fail to notice the winds of change: changes in the individual programmes of the Member States are now progressively moving from paper studies to realistic site specific investigations; changes in the very orientation of INDAG, in which the accent is now more and more on technical issues and discussions; and changes in the Newsletter itself - in this issue you have not one but three technical notes (see the insert: INDAG Technical Brief), summarising the presentations made during the last INDAG Meeting held from 10 to 12 July, 2002. Reflecting these changes, INDAG has recommended the organisation of Technical Meetings to take place in alternate years between INDAG meetings. Yet another domain where noticeable changes are apparent is the area of International collaborations, which have become realities from just ideas. The EURODESAL project is well underway. This is also the case for the collaboration between South Korea and Indonesia, between France and Tunisia and between France and Morocco, all three dealing with site-specific studies with a view to furnish technical and economic specifications for eventual, integrated nuclear desalination plants. The collaboration between Russia and Canada on a floating nuclear desalination facility continues at an advanced stage
International Nuclear Information System (INIS)
2000-01-01
Almost 25 years after its foundation, the IAEA/WHO Network of SSDLs comprises 70 members in 59 Member States and is supported by 15 Primary Standards Dosimetry Laboratories and 5 international bodies and committees. The close link between the Network and other metrology bodies has contributed substantially to achieving consistency in the dosimetry of ionizing radiation. The first article of this issue of the SSDL Newsletter is devoted to the story of SSDL under the title 'the SSDL story' so that the 'SSDL memory' becomes recorded. The second article is a report of the Third Research Co-ordination Meeting (RCM) for the Coordinated Research Project (CRP E2.10.02) on 'the development of a quality assurance programme for SSDLs', held at the IAEA Headquarters from 29 November to 3 December 1999. The objective of the CRP is to prepare practical guidelines to SSDLs for the development of a quality system based on ISO/IEC standards. The main results achieved under this CRP are included in this report and will be published in the form of an IAEA document to be distributed to all SSDL members. The third article is a report from the SSDL in Tanzania, which describes the quality control programme implemented in the laboratory
International Nuclear Information System (INIS)
2001-09-01
The International Nuclear Desalination Advisory Group, INDAG, was created following the 1996 General Conference Resolution (GC(40)/RES/14) requesting the IAEA to take the appropriate measures to assist Member States in the process of preparatory actions for nuclear desalination demonstration projects. This resolution was reiterated in the following IAEA General Conferences and INDAG is now in its second term, ending in 2004. From its very beginning, INDAG has actively contributed to the promotion and stimulation of nuclear desalination activities in IAEA Member States. Its achievements are numerous but they are perhaps relatively less well known to people outside IAEA and related organisations. INDAG, through its meetings, has provided common methodology, computer tools and activities which have encouraged other Member States to engage in nuclear desalination activities in a more coherent manner. Similarly, under INDAG recommendations and suggestions, IAEA has already implemented important activities for the promotion of the cause for nuclear desalination in the world launching of the Coordinated Research Program on 'Optimisation of the coupling of nuclear reactors and desalination systems' (1998-2003). This first issue of the Newsletter prepared by INDAG members brings not only a report of INDAG activities but presents the latest innovations and advances taking place in Member States in the field of nuclear desalination
IEC Newsletter, No. 50, Fourth Quarter, 2014
International Nuclear Information System (INIS)
2014-12-01
The IEC Newsletter is prepared by the Incident and Emergency Centre (IEC), Department of Nuclear Safety and Security of the IAEA. The Incident and Emergency Centre (… IEC) is the global focal point for emergency preparedness and response for nuclear and radiological safety or security related incidents, emergencies, threats or events of media interest. The IEC is also the world’s centre for coordination of international assistance in emergency. The following topics are presented in this newsletter: Three Workshops at the Fukushima RANET Capacity Building Centre; Belgium joins RANET; IEC Response to Recent Events; Recent Exercises; Israel conducts National Response Exercise at Soreq; IACRNE: 24th Regular Meeting; Safety Requirements on Emergency Preparedness and Response; NIRS 2014 Workshop on Radiation Emergency Medicine; Member State Preparedness; New Publications and Translations and Forthcoming Events
ITER EDA Newsletter. V.3, no.4
International Nuclear Information System (INIS)
1994-04-01
This ITER EDA Newsletter issue contains a report on the fifth meeting of the ITER Management Advisory Committee and a summary of a magnet and safety technical meeting held at Naka, February 22-25, 1994
ITER EDA newsletter. V. 9, no. 6
International Nuclear Information System (INIS)
2000-06-01
This newsletter contains the reports of the twelfth meeting of the ITER physics expert group on diagnostics and the 14. international conference on plasma-surface interactions in controlled fusion devices. Individual abstracts have been prepared
Soils Newsletter. V. 12, no. 1
International Nuclear Information System (INIS)
1989-07-01
This Newsletter includes a report of the second research co-ordination meeting on the use of isotopes to improve yield and nitrogen fixation of the common bean in Latin America (April 1989, Irapuato, Mexico), and describes some of the technical co-operation programmes in the Africa region
TASCC newsletter volume 7 no. 10
International Nuclear Information System (INIS)
Thomson, L.
1993-10-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this October issue of TASCC is an update of the facility report, ECR ion source development, new measurement of Carbon 10, Penning-trap mass spectrometer and a listing of October's experiments. 2 figs
Soils Newsletter. V. 13, no. 1
International Nuclear Information System (INIS)
1990-07-01
This Newsletter includes a report on the recently completed co-ordinated research programme on the use of nuclear techniques in improving pasture management, and briefly describes the technical co-operation programme on the effect of changing land use on the ecology and climate of the Brazilian Amazon
TASCC newsletter volume 8 no. 8
International Nuclear Information System (INIS)
Thomson, L.
1994-08-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this August issue of TASCC is an update of the facility, personnel changes at TASCC, awards to TASCC personnel, workshop on deflectors, beam calculations on PC's and a listing of August's experiments. 2 figs
Animal production and health newsletter. No. 39
Energy Technology Data Exchange (ETDEWEB)
NONE
2004-01-01
In addition to highlights of research coordination meetings, training events and announcements of upcoming events, this issue of the Newsletter carries editorial note regarding the potential of biotechnology in animal health and production for developing countries.
Animal production and health newsletter. No. 39
International Nuclear Information System (INIS)
2004-01-01
In addition to highlights of research coordination meetings, training events and announcements of upcoming events, this issue of the Newsletter carries editorial note regarding the potential of biotechnology in animal health and production for developing countries
Directory of Open Access Journals (Sweden)
Xiaoping Chen
Full Text Available We tested the ability of the axolotl (Ambystoma mexicanum fibula to regenerate across segment defects of different size in the absence of intervention or after implant of a unique 8-braid pig small intestine submucosa (SIS scaffold, with or without incorporated growth factor combinations or tissue protein extract. Fractures and defects of 10% and 20% of the total limb length regenerated well without any intervention, but 40% and 50% defects failed to regenerate after either simple removal of bone or implanting SIS scaffold alone. By contrast, scaffold soaked in the growth factor combination BMP-4/HGF or in protein extract of intact limb tissue promoted partial or extensive induction of cartilage and bone across 50% segment defects in 30%-33% of cases. These results show that BMP-4/HGF and intact tissue protein extract can promote the events required to induce cartilage and bone formation across a segment defect larger than critical size and that the long bones of axolotl limbs are an inexpensive model to screen soluble factors and natural and synthetic scaffolds for their efficacy in stimulating this process.
ITER EDA newsletter. V. 7, no. 7
International Nuclear Information System (INIS)
1998-07-01
This newsletter contains the articles: 'Extraordinary ITER council meeting', 'ITER EDA final safety meeting' and 'Summary report of the 3rd combined workshop of the ITER confinement and transport and ITER confinement database and modeling expert groups'
TASCC newsletter volume 7 no. 7
International Nuclear Information System (INIS)
Thomson, L.
1993-07-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this July issue information is gained on solar cells as fission detectors, database conversion to VISTA, a facility report on beam production, employment equity at TASCC and insight into the cyclotron electrostatic deflector behaviour. 3 figs
TASCC newsletter volume 5 no. 10
International Nuclear Information System (INIS)
Thomson, L.
1991-10-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this October issue is a report on the commissioning of the cyclotron, a new AMS test method for Chlorine 36 beam, a facility report and operating record and a listing of experiments conducted in October
TASCC newsletter volume 7 no. 10
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1993-10-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this October issue of TASCC is an update of the facility report, ECR ion source development, new measurement of Carbon 10, Penning-trap mass spectrometer and a listing of October`s experiments. 2 figs.
TASCC newsletter volume 7 no. 4
International Nuclear Information System (INIS)
Thomson, L.
1993-04-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in the April issue is information on damage tests of satellite instrumentation, general news on success of beams achieved, assessment by NPPAP panel on TASCC programs, staff changes and a listing of April's experiments. 2 figs
TASCC newsletter volume 8 no. 6
International Nuclear Information System (INIS)
Thomson, L.
1994-06-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this June issue of TASCC is an update of the facility, a review of federal strategy for science and technology, construction on the Canadian Penning Trap Mass Spectrometer and a listing of June's experiments. 1 fig
Fermilab Friends for Science Education | Newsletters
FFSE members receive a newsletter twice each year, in the fall and in the winter. Links to the current issue and past issues are available below. Spring 2012 Volunteers Extraordinaire, Education Office staff , Responding to Lab-wide Changes, 2012 Events: Mark Your Calendar!, Board of Directors Changes, ??? A Question
International Nuclear Information System (INIS)
2005-02-01
Powernext SA is a Multilateral Trading Facility which organizes and warrants the transactions on the European power exchange market. This issue of Powernext newsletter presents the highlights of the European power trade markets during January, February and March 2005. It reports on some daily market statistics related to prices and volumes traded on Powernext Day-Ahead TM in the case of day-ahead contracts, and on Powernext Futures TM in the case of medium-term contracts. (J.S.)
International Nuclear Information System (INIS)
2005-04-01
Powernext SA is a Multilateral Trading Facility which organizes and warrants the transactions on the European power exchange market. This issue of Powernext newsletter presents the highlights of the European power trade markets during February, March and April 2005. It reports on some daily market statistics related to prices and volumes traded on Powernext Day-Ahead TM in the case of day-ahead contracts, and on Powernext Futures TM in the case of medium-term contracts. (J.S.)
Directory of Open Access Journals (Sweden)
Ji-Feng Fei
2014-09-01
Full Text Available The salamander is the only tetrapod that functionally regenerates all cell types of the limb and spinal cord (SC and thus represents an important regeneration model, but the lack of gene-knockout technology has limited molecular analysis. We compared transcriptional activator-like effector nucleases (TALENs and clustered regularly interspaced short palindromic repeats (CRISPRs in the knockout of three loci in the axolotl and find that CRISPRs show highly penetrant knockout with less toxic effects compared to TALENs. Deletion of Sox2 in up to 100% of cells yielded viable F0 larvae with normal SC organization and ependymoglial cell marker expression such as GFAP and ZO-1. However, upon tail amputation, neural stem cell proliferation was inhibited, resulting in spinal-cord-specific regeneration failure. In contrast, the mesodermal blastema formed normally. Sox3 expression during development, but not regeneration, most likely allowed embryonic survival and the regeneration-specific phenotype. This analysis represents the first tissue-specific regeneration phenotype from the genomic deletion of a gene in the axolotl.
ITER EDA newsletter. V. 9, no. 2
International Nuclear Information System (INIS)
2000-02-01
This ITER EDA Newsletter reports on the seventh ITER technical meeting on safety and environment and contains the executive summary of the eleventh ITER scrape-off layer and divertor physics expert group meeting. Individual abstracts have been prepared
ITER EDA newsletter. V. 2, no. 11
International Nuclear Information System (INIS)
1993-11-01
This issue of the ITER EDA (Engineering Design Activities) Newsletter contains an ITER EDA Status Report, and a report on the Fourth International Fusion Neutronics Workshop at the University of California, Los Angeles Campus, October 20-21, 1993
Itese Newsletter, Number 23 - Autumn 2014
International Nuclear Information System (INIS)
Devezeaux de Lavergne, Jean-Guy; Gabriel, Sophie; Jasserand, Frederic; Le Duigou, Alain; Le Net, Elisabeth; Mansilla, Christine; Maziere, Dominique; Monnet, Antoine; Popiolek, Nathalie; Thais, Francoise; Yu, Julie
2014-01-01
The first article of this newsletter describes some aspects of the role of hydrogen in energy transition. It outlines the sensitivity of the production cost to the business model, the great number of applications of hydrogen as a chemical product and as an energy vector, the promising applications in mobility and transport, the good public image of this product, and the role hydrogen could play in energy transition. The second article comments the recent evolutions of the uranium market and outlines the perspective of concentration of mining companies, notably state companies. The third article proposes a comparative analysis of public policies in favour of solar photovoltaic development between Germany and China (in terms of objectives, of inputs and results, of production and installations). It also highlights the interactions between the photovoltaic policy strategies of both countries. The next article addresses the project development of two EPR nuclear reactors at Hinkley Point in the UK with the favourable recommendation of the European Competition Commission. Some brief news are then proposed (mainly about recent international meetings on energy and on uranium non conventional resources)
Environment Laboratories Newsletter. Vol. 1, No. 01, Jan.-Jun. 2014
International Nuclear Information System (INIS)
2014-01-01
This is the first edition of the newsletter of the IAEA Environment Laboratories. This replaces the former Marine Environment Laboratories newsletter, reflecting a restructure that has seen the marine and terrestrial environment laboratories of the IAEA integrated into a single division. The IAEA’s Environment Laboratories in Monaco and Seibersdorf, Austria, in partnership with several collaborating centres around the globe, are unique in the UN system. Through the use and promotion of nuclear and isotopic techniques, the Environment Laboratories play a major role in the journey towards sustainable development, both on land and at sea. Responding to requests for technical assistance from Member States and other UN agencies, the Environment Laboratories provide applied collaborative research, training courses, technical cooperation projects and analytical quality support services for radioactive and non-radioactive contaminants in the environment. Through its environmental programme the IAEA promotes an integrated approach to the study, monitoring and protection of marine, coastal and terrestrial pollution, climate change and the loss of habitat. In this first edition we focus on the challenge of ocean acidification. Governments across the globe are calling for immediate action to minimize and address the impacts of ocean acidification which will require enhanced scientific cooperation at all levels. The IAEA Environment Laboratories will play a key role in this area and are proud to host the Ocean Acidification International Coordination Centre. We are also happy to include in this edition the winners of the 2014 World Oceans Day (WOD) photo competition
Animal production and health newsletter. No. 46, July 2007
International Nuclear Information System (INIS)
2007-07-01
In response to many requests from our readers, I will continue to highlight a practical topic related to animal production and health in this section of the newsletter. Increasing the efficiency of animal reproduction is a critical component of a holistic approach to sustainably increase animal productivity in developing Member States. For example, the resources spent to formulate and obtain the ingredients for dairy rations are wasted when a significant proportion of the cows in the herd are dry due to delays in achieving pregnancy. Effective genetic selection to improve productivity is only possible if a regular supply of potential replacements is generated by the females already in the herd or flock. For this reason, improving reproductive efficiency is a key aspect of many of the APH projects
Jarial, M S
1989-01-01
The fine structure of the Leydig cells in the epidermis of the strictly aquatic adult axolotl Ambystoma mexicanum resembles that of similar cells in larval salamanders. The major finding of this study is that the mucous secretion of the Leydig cells is released into the intercellular spaces from which it is discharged through pores onto the surface of the epidermis where it forms a mucous layer to protect the skin. Images Figs. 1-2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 Fig. 10 Figs. 11-13 PMID:2630544
Newsletter: work of the Committee and projects funded
Energy Technology Data Exchange (ETDEWEB)
1974-12-01
Information about the work of the Committee is summarized. It has developed a series of project priorities. These are as follows in order of priority: projects that determine current and future energy demand; projects concerned with the conservation and more efficient use of energy; projects concerned with the assessment of indigenous energy resources; projects concerned with the assessment of the human, financial, and organizational resources for increasing energy production and use; projects concerned with economic, technological, and environmental aspects of energy use and production over the next 15 years and beyond the next 15 years. In addition, environmental and sociological projects are considered to be very important. All projects are required to have included consideration of environmental and sociological issues but there may also be specific environmental projects such as the one related to cooling water pond modelling (MCW)
IDRA Newsletter. Volume 37, No. 4
Goodman, Christie L., Ed.
2010-01-01
Each edition of the IDRA Newsletter strives to provide many different perspectives on the issues in education topics discussed and to define its significance in the state and national dialogue. This issue focuses on Parent and Community Engagement and includes: (1) Principles of Family Leadership in Education--Putting Principles into Action…
TASCC newsletter volume 8 no. 9
International Nuclear Information System (INIS)
Thomson, L.
1994-09-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this September issue of TASCC is an update of the facility, winner of Nobel prize, dating of fossil seeds using Chlorine 36, promotion of TASCC at a local fair and a listing of September's experiments. 1 fig
TASCC newsletter volume 7 no. 4
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1993-04-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in the April issue is information on damage tests of satellite instrumentation, general news on success of beams achieved, assessment by NPPAP panel on TASCC programs, staff changes and a listing of April`s experiments. 2 figs.
TASCC newsletter volume 8 no. 6
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1994-06-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this June issue of TASCC is an update of the facility, a review of federal strategy for science and technology, construction on the Canadian Penning Trap Mass Spectrometer and a listing of June`s experiments. 1 fig.
TASCC newsletter volume 8 no. 8
Energy Technology Data Exchange (ETDEWEB)
Thomson, L
1994-08-01
A newsletter produced by Chalk River`s Tandem Accelerator Superconducting Cyclotron Facility. Included in this August issue of TASCC is an update of the facility, personnel changes at TASCC, awards to TASCC personnel, workshop on deflectors, beam calculations on PC`s and a listing of August`s experiments. 2 figs.
TASCC newsletter volume 7 no. 8
International Nuclear Information System (INIS)
Thomson, L.
1993-08-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this August issue is information on the status of the TRC's written report, visitors to TASCC, the facility report and new intruder bands that were discovered, as well as a listing of August 's experiments. 2 figs
TASCC newsletter volume 9 no. 7
International Nuclear Information System (INIS)
Thomson, L.
1995-07-01
A newsletter produced by Chalk River's Tandem Accelerator Superconducting Cyclotron Facility. Included in this July issue of TASCC is an update of the facility, submission of report by the Program Advisory Committee, government program review begins at AECL, awards to TASCC personnel and a listing of July's experiments. 2 figs
Soils newsletter. V. 20, no. 1
International Nuclear Information System (INIS)
1997-07-01
The newsletter reports highlights of the third Research Coordination Meeting of the IAEA/FAO CRP on ''the use of Nuclear and related techniques for evaluating the agronomic effectiveness of phosphate fertilizers, in particular rock phosphates'' which was held in Vienna, Austria, 17-21, 1997. Training seminars conducted are also discussed
Plant breeding and genetics newsletter. No. 17, July 2006
International Nuclear Information System (INIS)
2006-07-01
The Plant Breeding and Genetics (PBG) Section of the Joint FAO/IAEA Programme (NAFA/AGE) recently implemented two Research Coordination Meetings (RCMs). Particular attention was given to the first RCM of the Coordinated Research Project (CRP) on Assessment of Nutrients Uptake from Bio-fortified Crops in Populations from Developing Countries, Vienna, Austria, 17-19 May 2006, which was co-organized with our nutritionist colleagues from the Division of Human Health, Nuclear Applications Department (NAHU), and sponsored by Harvest Plus. Hidden hunger and enhancing crop quality for nutrition will be given increased attention in the new biennium 2008-2009. We encourage you to share your input with us on this subject. Several training courses were implemented in the framework of different Technical Cooperation (TC) projects. Details about these activities are covered in this issue of the Newsletter. A highlight of these activities, as in every year since 2001, was the Inter-regional Training Course on Mutant Germplasm Characterization using Molecular Markers at the Seibersdorf Laboratories, Seibersdorf, Austria, 14 May to 16 June 2006
International Nuclear Information System (INIS)
Ondracek, G.
1977-12-01
There are three groups of contributions forming the present Newsletter in Stereology which are such of theoretical type, stereological activities in bio-sciences and quatitative image analysis in materials science. The report is introduced by two papers treating theoretical problems as the definition of particle size based on the total curvature and the definition of pattern recognition categories. It than follows a summarizing description and comparison of alternative techniques used to measure and conclude stereological parameters in bio-sciences. The discussion includes the sample preparation, semi- and complete automatic measuring procedures as well as the computation of primary data. The biological part ends by considering the use of those quantitative microscopical methods to investigate and classify foreign compounds inside the human liver stereologically. The materials science part reports about tests made on steel specimens to evaluate the accuracy of automatic microstructural analyses and about the use of image 'erosion' and 'dilatation' to measure microstructural parameters automatically. The last subject is part of a serie on morphology in quantitative metallography started in the previous Newsletter '76. The last paper on materials sciences considers the use of stereology and microstructural analysis in respect to a quality control, choosing WC-Co hardmetals as an example, where stereologically defined microstructural parameters do not serve only to describe microstructures quantitatively but also provide a usefull tool to determine properties indirectly. (orig.) [de
ITER EDA newsletter. V. 8, no. 8
International Nuclear Information System (INIS)
1999-08-01
This ITER EDA newsletter reports on the programme directors meeting of 28-29 July 1999, the Snowmass Fusion Summer Study Group workshop and the ITER Management Advisory Committee meeting in Garching. Individual abstracts are prepared for the 3 meetings
Nuclear power newsletter Vol. 2, no. 2
International Nuclear Information System (INIS)
2005-06-01
The main topics in the newsletter are: International Ministerial Conference 'Nuclear Power for the 21st Century 'NPP operating performance and life cycle management; improving human performance quality and technical infrastructure; and technology development and applications for advanced reactors
Solar Energy Technologies Program Newsletter - Fourth Quarter 2009
Energy Technology Data Exchange (ETDEWEB)
DOE Solar Energy Technologies Program
2009-12-31
The Fourth Quarter 2009 edition of the Solar Energy Technologies Program newsletter summarizes the activities for the past three months, funding opportunities, highlights from the national labs, and upcoming events.
Mutation breeding newsletter. Index issue no. 11-20
International Nuclear Information System (INIS)
1984-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants
Mutation breeding newsletter. Index issue no. 11-20
Energy Technology Data Exchange (ETDEWEB)
NONE
1984-01-01
This issue of the Newsletter presents new reports on mutation breeding programs using radiation or chemical mutagenesis to improve productivity, introduce disease resistance or induce morphological changes in crop plants.
Nuclear data newsletter. No. 35
International Nuclear Information System (INIS)
2003-04-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and relevant computer codes and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres
Nuclear data newsletter. No. 34
International Nuclear Information System (INIS)
2002-10-01
This periodic newsletter provides information relevant to the work of the IAEA Nuclear Data Section. This issue announces the online and offline news concerning nuclear data libraries and data processing codes. It includes announcements on development activities of IAEA in the field of nuclear data collections and relevant computer codes and lists selected reports and documents on nuclear data as well as cooperating nuclear data service centres