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Sample records for program lkb resources

  1. LKB1 promotes metabolic flexibility in response to energy stress.

    Science.gov (United States)

    Parker, Seth J; Svensson, Robert U; Divakaruni, Ajit S; Lefebvre, Austin E; Murphy, Anne N; Shaw, Reuben J; Metallo, Christian M

    2017-09-01

    The Liver Kinase B1 (LKB1) tumor suppressor acts as a metabolic energy sensor to regulate AMP-activated protein kinase (AMPK) signaling and is commonly mutated in various cancers, including non-small cell lung cancer (NSCLC). Tumor cells deficient in LKB1 may be uniquely sensitized to metabolic stresses, which may offer a therapeutic window in oncology. To address this question we have explored how functional LKB1 impacts the metabolism of NSCLC cells using 13 C metabolic flux analysis. Isogenic NSCLC cells expressing functional LKB1 exhibited higher flux through oxidative mitochondrial pathways compared to those deficient in LKB1. Re-expression of LKB1 also increased the capacity of cells to oxidize major mitochondrial substrates, including pyruvate, fatty acids, and glutamine. Furthermore, LKB1 expression promoted an adaptive response to energy stress induced by anchorage-independent growth. Finally, this diminished adaptability sensitized LKB1-deficient cells to combinatorial inhibition of mitochondrial complex I and glutaminase. Together, our data implicate LKB1 as a major regulator of adaptive metabolic reprogramming and suggest synergistic pharmacological strategies for mitigating LKB1-deficient NSCLC tumor growth. Copyright © 2016. Published by Elsevier Inc.

  2. LKB1 regulates lipid oxidation during exercise independently of AMPK

    DEFF Research Database (Denmark)

    Jeppesen, Jacob Fuglsbjerg; Maarbjerg, Stine Just; Jordy, Andreas Børsting

    2013-01-01

    Lipid metabolism is important for health and insulin action, yet the fundamental process of regulating lipid metabolism during muscle contraction is incompletely understood. Here, we show that LKB1 muscle-specific knockout (LKB1 MKO) mice display decreased fatty acid (FA) oxidation during treadmi...

  3. Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.

    Science.gov (United States)

    Gaude, H; Aznar, N; Delay, A; Bres, A; Buchet-Poyau, K; Caillat, C; Vigouroux, A; Rogon, C; Woods, A; Vanacker, J-M; Höhfeld, J; Perret, C; Meyer, P; Billaud, M; Forcet, C

    2012-03-22

    LKB1 is a tumor suppressor that is constitutionally mutated in a cancer-prone condition, called Peutz-Jeghers syndrome, as well as somatically inactivated in a sizeable fraction of lung and cervical neoplasms. The LKB1 gene encodes a serine/threonine kinase that associates with the pseudokinase STRAD (STE-20-related pseudokinase) and the scaffolding protein MO25, the formation of this heterotrimeric complex promotes allosteric activation of LKB1. We have previously reported that the molecular chaperone heat shock protein 90 (Hsp90) binds to and stabilizes LKB1. Combining pharmacological studies and RNA interference approaches, we now provide evidence that the co-chaperone Cdc37 participates to the regulation of LKB1 stability. It is known that the Hsp90-Cdc37 complex recognizes a surface within the N-terminal catalytic lobe of client protein kinases. In agreement with this finding, we found that the chaperones Hsp90 and Cdc37 interact with an LKB1 isoform that differs in the C-terminal region, but not with a novel LKB1 variant that lacks a portion of the kinase N-terminal lobe domain. Reconstitution of the two complexes LKB1-STRAD and LKB1-Hsp90-Cdc37 with recombinant proteins revealed that the former is catalytically active whereas the latter is inactive. Furthermore, consistent with a documented repressor function of Hsp90, LKB1 kinase activity was transiently stimulated upon dissociation of Hsp90. Finally, disruption of the LKB1-Hsp90 complex favors the recruitment of both Hsp/Hsc70 and the U-box dependent E3 ubiquitin ligase CHIP (carboxyl terminus of Hsc70-interacting protein) that triggers LKB1 degradation. Taken together, our results establish that the Hsp90-Cdc37 complex controls both the stability and activity of the LKB1 kinase. This study further shows that two chaperone complexes with antagonizing activities, Hsp90-Cdc37 and Hsp/Hsc70-CHIP, finely control the cellular level of LKB1 protein.

  4. Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice.

    Science.gov (United States)

    Claret, Marc; Smith, Mark A; Knauf, Claude; Al-Qassab, Hind; Woods, Angela; Heslegrave, Amanda; Piipari, Kaisa; Emmanuel, Julian J; Colom, André; Valet, Philippe; Cani, Patrice D; Begum, Ghazala; White, Anne; Mucket, Phillip; Peters, Marco; Mizuno, Keiko; Batterham, Rachel L; Giese, K Peter; Ashworth, Alan; Burcelin, Remy; Ashford, Michael L; Carling, David; Withers, Dominic J

    2011-03-01

    AMP-activated protein kinase (AMPK) signaling acts as a sensor of nutrients and hormones in the hypothalamus, thereby regulating whole-body energy homeostasis. Deletion of Ampkα2 in pro-opiomelanocortin (POMC) neurons causes obesity and defective neuronal glucose sensing. LKB1, the Peutz-Jeghers syndrome gene product, and Ca(2+)-calmodulin-dependent protein kinase kinase β (CaMKKβ) are key upstream activators of AMPK. This study aimed to determine their role in POMC neurons upon energy and glucose homeostasis regulation. Mice lacking either Camkkβ or Lkb1 in POMC neurons were generated, and physiological, electrophysiological, and molecular biology studies were performed. Deletion of Camkkβ in POMC neurons does not alter energy homeostasis or glucose metabolism. In contrast, female mice lacking Lkb1 in POMC neurons (PomcLkb1KO) display glucose intolerance, insulin resistance, impaired suppression of hepatic glucose production, and altered expression of hepatic metabolic genes. The underlying cellular defect in PomcLkb1KO mice involves a reduction in melanocortin tone caused by decreased α-melanocyte-stimulating hormone secretion. However, Lkb1-deficient POMC neurons showed normal glucose sensing, and body weight was unchanged in PomcLkb1KO mice. Our findings demonstrate that LKB1 in hypothalamic POMC neurons plays a key role in the central regulation of peripheral glucose metabolism but not body-weight control. This phenotype contrasts with that seen in mice lacking AMPK in POMC neurons with defects in body-weight regulation but not glucose homeostasis, which suggests that LKB1 plays additional functions distinct from activating AMPK in POMC neurons.

  5. Deletion of Lkb1 in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

    Science.gov (United States)

    Claret, Marc; Smith, Mark A.; Knauf, Claude; Al-Qassab, Hind; Woods, Angela; Heslegrave, Amanda; Piipari, Kaisa; Emmanuel, Julian J.; Colom, André; Valet, Philippe; Cani, Patrice D.; Begum, Ghazala; White, Anne; Mucket, Phillip; Peters, Marco; Mizuno, Keiko; Batterham, Rachel L.; Giese, K. Peter; Ashworth, Alan; Burcelin, Remy; Ashford, Michael L.; Carling, David; Withers, Dominic J.

    2011-01-01

    OBJECTIVE AMP-activated protein kinase (AMPK) signaling acts as a sensor of nutrients and hormones in the hypothalamus, thereby regulating whole-body energy homeostasis. Deletion of Ampkα2 in pro-opiomelanocortin (POMC) neurons causes obesity and defective neuronal glucose sensing. LKB1, the Peutz-Jeghers syndrome gene product, and Ca2+-calmodulin–dependent protein kinase kinase β (CaMKKβ) are key upstream activators of AMPK. This study aimed to determine their role in POMC neurons upon energy and glucose homeostasis regulation. RESEARCH DESIGN AND METHODS Mice lacking either Camkkβ or Lkb1 in POMC neurons were generated, and physiological, electrophysiological, and molecular biology studies were performed. RESULTS Deletion of Camkkβ in POMC neurons does not alter energy homeostasis or glucose metabolism. In contrast, female mice lacking Lkb1 in POMC neurons (PomcLkb1KO) display glucose intolerance, insulin resistance, impaired suppression of hepatic glucose production, and altered expression of hepatic metabolic genes. The underlying cellular defect in PomcLkb1KO mice involves a reduction in melanocortin tone caused by decreased α-melanocyte–stimulating hormone secretion. However, Lkb1-deficient POMC neurons showed normal glucose sensing, and body weight was unchanged in PomcLkb1KO mice. CONCLUSIONS Our findings demonstrate that LKB1 in hypothalamic POMC neurons plays a key role in the central regulation of peripheral glucose metabolism but not body-weight control. This phenotype contrasts with that seen in mice lacking AMPK in POMC neurons with defects in body-weight regulation but not glucose homeostasis, which suggests that LKB1 plays additional functions distinct from activating AMPK in POMC neurons. PMID:21266325

  6. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines

    International Nuclear Information System (INIS)

    Mack, Hildegard I.D.; Munger, Karl

    2013-01-01

    Infection with high-risk human papillomaviruses is causally linked to cervical carcinogenesis. However, most lesions caused by high-risk HPV infections do not progress to cancer. Host cell mutations contribute to malignant progression but the molecular nature of such mutations is unknown. Based on a previous study that reported an association between liver kinase B1 (LKB1) tumor suppressor loss and poor outcome in cervical cancer, we sought to determine the molecular basis for this observation. LKB1-negative cervical and lung cancer cells were reconstituted with wild type or kinase defective LKB1 mutants and we examined the importance of LKB1 catalytic activity in known LKB1-regulated processes including inhibition of cell proliferation and elevated resistance to energy stress. Our studies revealed marked differences in the biological activities of two kinase defective LKB1 mutants in the various cell lines. Thus, our results suggest that LKB1 may be a cell-type specific tumor suppressor. - Highlights: • LKB1 is a tumor suppressor that is linked to Peutz-Jeghers syndrome. • Peutz-Jeghers syndrome patients have a high incidence of cervical cancer. • Cervical cancer is caused by HPV infections. • This study investigates LKB1 tumor suppressor activity in cervical cancer

  7. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress

    KAUST Repository

    Ritho, Joan

    2015-07-23

    SUMOylation has been implicated in cellular stress adaptation, but its role in regulating liver kinase B1 (LKB1), a major upstream kinase of the energy sensor AMP-activated protein kinase (AMPK), is unknown. Here, we show that energy stress triggers an increase in SUMO1 modification of LKB1, despite a global reduction in both SUMO1 and SUMO2/3 conjugates. During metabolic stress, SUMO1 modification of LKB1 lysine 178 is essential in promoting its interaction with AMPK via a SUMO-interacting motif (SIM) essential for AMPK activation. The LKB1 K178R SUMO mutant had defective AMPK signaling and mitochondrial function, inducing death in energy-deprived cells. These results provide additional insight into how LKB1-AMPK signaling is regulated during energy stress, and they highlight the critical role of SUMOylation in maintaining the cell’s energy equilibrium.

  8. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress

    KAUST Repository

    Ritho, Joan; Arold, Stefan T.; Yeh, Edward  T.H.

    2015-01-01

    SUMOylation has been implicated in cellular stress adaptation, but its role in regulating liver kinase B1 (LKB1), a major upstream kinase of the energy sensor AMP-activated protein kinase (AMPK), is unknown. Here, we show that energy stress triggers an increase in SUMO1 modification of LKB1, despite a global reduction in both SUMO1 and SUMO2/3 conjugates. During metabolic stress, SUMO1 modification of LKB1 lysine 178 is essential in promoting its interaction with AMPK via a SUMO-interacting motif (SIM) essential for AMPK activation. The LKB1 K178R SUMO mutant had defective AMPK signaling and mitochondrial function, inducing death in energy-deprived cells. These results provide additional insight into how LKB1-AMPK signaling is regulated during energy stress, and they highlight the critical role of SUMOylation in maintaining the cell’s energy equilibrium.

  9. LKB1 mediates the development of conventional and innate T cells via AMP-dependent kinase autonomous pathways.

    Directory of Open Access Journals (Sweden)

    Marouan Zarrouk

    Full Text Available The present study has examined the role of the serine/threonine kinase LKB1 in the survival and differentiation of CD4/8 double positive thymocytes. LKB1-null DPs can respond to signals from the mature α/β T-cell-antigen receptor and initiate positive selection. However, in the absence of LKB1, thymocytes fail to mature to conventional single positive cells causing severe lymphopenia in the peripheral lymphoid tissues. LKB1 thus appears to be dispensable for positive selection but important for the maturation of positively selected thymocytes. LKB1 also strikingly prevented the development of invariant Vα14 NKT cells and innate TCR αβ gut lymphocytes. Previous studies with gain of function mutants have suggested that the role of LKB1 in T cell development is mediated by its substrate the AMP-activated protein kinase (AMPK. The present study now analyses the impact of AMPK deletion in DP thymocytes and shows that the role of LKB1 during the development of both conventional and innate T cells is mediated by AMPK-independent pathways.

  10. Recent Progress on Liver Kinase B1 (LKB1: Expression, Regulation, Downstream Signaling and Cancer Suppressive Function

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    Ren-You Gan

    2014-09-01

    Full Text Available Liver kinase B1 (LKB1, known as a serine/threonine kinase, has been identified as a critical cancer suppressor in many cancer cells. It is a master upstream kinase of 13 AMP-activated protein kinase (AMPK-related protein kinases, and possesses versatile biological functions. LKB1 gene is mutated in many cancers, and its protein can form different protein complexes with different cellular localizations in various cell types. The expression of LKB1 can be regulated through epigenetic modification, transcriptional regulation and post-translational modification. LKB1 dowcnstream pathways mainly include AMPK, microtubule affinity regulating kinase (MARK, salt-inducible kinase (SIK, sucrose non-fermenting protein-related kinase (SNRK and brain selective kinase (BRSK signalings, etc. This review, therefore, mainly discusses recent studies about the expression, regulation, downstream signaling and cancer suppressive function of LKB1, which can be helpful for better understanding of this molecular and its significance in cancers.

  11. Par3L enhances colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway

    International Nuclear Information System (INIS)

    Li, Taiyuan; Liu, Dongning; Lei, Xiong; Jiang, Qunguang

    2017-01-01

    Partitioning defective 3-like protein (Par3L) is a recently identified cell polarity protein that plays an important role in mammary stem cell maintenance. Previously, we showed that high expression of Par3L is associated with poor survival in malignant colorectal cancer (CRC), but the underlying mechanism remained unknown. To this end, we established a Par3L knockout colorectal cancer cell line using the CRISPR/Cas system. Interestingly, reduced proliferation, enhanced cell death and caspase-3 activation were observed in Par3L knockout (KO) cells as compared with wildtype (WT) cells. Consistent with previous studies, we showed that Par3L interacts with a tumor suppressor protein liver kinase B1 (Lkb1). Moreover, Par3L depletion resulted in abnormal activation of Lkb1/AMPK signaling cascade. Knockdown of Lkb1 in these cells could significantly reduce AMPK activity and partially rescue cell death caused by Par3L knockdown. Furthermore, we showed that Par3L KO cells were more sensitive to chemotherapies and irradiation. Together, these results suggest that Par3L is essential for colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway, and is a putative therapeutic target for CRC. - Highlights: • Par3L knockout using the CRISPR/Cas system induces apoptosis in colorectal cancer cells. • Par3L interacts with Lkb1 and regulates the activity of AMPK signaling cascade. • Par3L knockout cells are more sensitive to treatment of different chemotherapy drugs and irradiation.

  12. Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

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    Alessi Dario R

    2003-09-01

    Full Text Available Abstract Background The AMP-activated protein kinase (AMPK cascade is a sensor of cellular energy charge that acts as a 'metabolic master switch' and inhibits cell proliferation. Activation requires phosphorylation of Thr172 of AMPK within the activation loop by upstream kinases (AMPKKs that have not been identified. Recently, we identified three related protein kinases acting upstream of the yeast homolog of AMPK. Although they do not have obvious mammalian homologs, they are related to LKB1, a tumor suppressor that is mutated in the human Peutz-Jeghers cancer syndrome. We recently showed that LKB1 exists as a complex with two accessory subunits, STRADα/β and MO25α/β. Results We report the following observations. First, two AMPKK activities purified from rat liver contain LKB1, STRADα and MO25α, and can be immunoprecipitated using anti-LKB1 antibodies. Second, both endogenous and recombinant complexes of LKB1, STRADα/β and MO25α/β activate AMPK via phosphorylation of Thr172. Third, catalytically active LKB1, STRADα or STRADβ and MO25α or MO25β are required for full activity. Fourth, the AMPK-activating drugs AICA riboside and phenformin do not activate AMPK in HeLa cells (which lack LKB1, but activation can be restored by stably expressing wild-type, but not catalytically inactive, LKB1. Fifth, AICA riboside and phenformin fail to activate AMPK in immortalized fibroblasts from LKB1-knockout mouse embryos. Conclusions These results provide the first description of a physiological substrate for the LKB1 tumor suppressor and suggest that it functions as an upstream regulator of AMPK. Our findings indicate that the tumors in Peutz-Jeghers syndrome could result from deficient activation of AMPK as a consequence of LKB1 inactivation.

  13. Honokiol activates the LKB1–AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes

    International Nuclear Information System (INIS)

    Seo, Min Suk; Kim, Jung Hwan; Kim, Hye Jung; Chang, Ki Churl; Park, Sang Won

    2015-01-01

    Honokiol is a bioactive neolignan compound isolated from the species of Magnolia. This study was designed to elucidate the cellular mechanism by which honokiol alleviates the development of non-alcoholic steatosis. HepG2 cells were treated with honokiol for 1 h, and then exposed to 1 mM free fatty acid (FFA) for 24 h to simulate non-alcoholic steatosis in vitro. C57BL/6 mice were fed with a high-fat diet for 28 days, and honokiol (10 mg/kg/day) was daily treated. Honokiol concentration-dependently attenuated intracellular fat overloading and triglyceride (TG) accumulation in FFA-exposed HepG2 cells. These effects were blocked by pretreatment with an AMP-activated protein kinase (AMPK) inhibitor. Honokiol significantly inhibited sterol regulatory element-binding protein-1c (SREBP-1c) maturation and the induction of lipogenic proteins, stearoyl-CoA desaturase-1 (SCD-1) and fatty acid synthase (FAS) in FFA-exposed HepG2 cells, but these effects were blocked by pretreatment of an AMPK inhibitor. Honokiol induced AMPK phosphorylation and subsequent acetyl-CoA carboxylase (ACC) phosphorylation, which were inhibited by genetic deletion of liver kinase B1 (LKB1). Honokiol stimulated LKB1 phosphorylation, and genetic deletion of LKB1 blocked the effect of honokiol on SREBP-1c maturation and the induction of SCD-1 and FAS proteins in FFA-exposed HepG2 cells. Honokiol attenuated the increases in hepatic TG and lipogenic protein levels and fat accumulation in the mice fed with high-fat diet, while significantly induced LKB1 and AMPK phosphorylation. Taken together, our findings suggest that honokiol has an anti-lipogenic effect in hepatocytes, and this effect may be mediated by the LKB1–AMPK signaling pathway, which induces ACC phosphorylation and inhibits SREBP-1c maturation in hepatocytes. - Highlights: • Honokiol attenuates lipid accumulation induced by free fatty acid in hepatocyte. • Honokiol inhibits the increase in lipogenic enzyme levels induced by free fatty

  14. Honokiol activates the LKB1–AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Min Suk; Kim, Jung Hwan; Kim, Hye Jung; Chang, Ki Churl; Park, Sang Won, E-mail: parksw@gnu.ac.kr

    2015-04-15

    Honokiol is a bioactive neolignan compound isolated from the species of Magnolia. This study was designed to elucidate the cellular mechanism by which honokiol alleviates the development of non-alcoholic steatosis. HepG2 cells were treated with honokiol for 1 h, and then exposed to 1 mM free fatty acid (FFA) for 24 h to simulate non-alcoholic steatosis in vitro. C57BL/6 mice were fed with a high-fat diet for 28 days, and honokiol (10 mg/kg/day) was daily treated. Honokiol concentration-dependently attenuated intracellular fat overloading and triglyceride (TG) accumulation in FFA-exposed HepG2 cells. These effects were blocked by pretreatment with an AMP-activated protein kinase (AMPK) inhibitor. Honokiol significantly inhibited sterol regulatory element-binding protein-1c (SREBP-1c) maturation and the induction of lipogenic proteins, stearoyl-CoA desaturase-1 (SCD-1) and fatty acid synthase (FAS) in FFA-exposed HepG2 cells, but these effects were blocked by pretreatment of an AMPK inhibitor. Honokiol induced AMPK phosphorylation and subsequent acetyl-CoA carboxylase (ACC) phosphorylation, which were inhibited by genetic deletion of liver kinase B1 (LKB1). Honokiol stimulated LKB1 phosphorylation, and genetic deletion of LKB1 blocked the effect of honokiol on SREBP-1c maturation and the induction of SCD-1 and FAS proteins in FFA-exposed HepG2 cells. Honokiol attenuated the increases in hepatic TG and lipogenic protein levels and fat accumulation in the mice fed with high-fat diet, while significantly induced LKB1 and AMPK phosphorylation. Taken together, our findings suggest that honokiol has an anti-lipogenic effect in hepatocytes, and this effect may be mediated by the LKB1–AMPK signaling pathway, which induces ACC phosphorylation and inhibits SREBP-1c maturation in hepatocytes. - Highlights: • Honokiol attenuates lipid accumulation induced by free fatty acid in hepatocyte. • Honokiol inhibits the increase in lipogenic enzyme levels induced by free fatty

  15. Dosimetric characteristics of LKB:Cu,P solid TL detector

    International Nuclear Information System (INIS)

    Hashim, S.; Alajerami, Y.S.M.; Ghoshal, S.K.; Saleh, M.A.; Saripan, M.I.; Kadir, A.B.A.; Bradley, D.A.; Alzimami, K.

    2014-01-01

    The dosimetric characteristics of newly developed borate glass dosimeter modified with lithium and potassium carbonate (LKB) and co-doped with CuO and NH 4 H 2 PO 4 are reported. Broad peaks in the absence of any sharp peak confirms the amorphous nature of the prepared glass. A simple glow curve of Cu doped sample is observed with a single prominent peak (T m ) at 220 °C. The TL intensity response shows an enhancement of ∼100 times due to the addition of CuO (0.1 mol%) to LKB compound. A further enhancement of the intensity by a factor of 3 from the addition of 0.25 mol% NH 4 H 2 PO 4 as a co-dopant impurity is attributed to the creation of extra electron traps with consequent increase in energy transfer of radiation recombination centers. The TL yield performance of LKB:Cu,P with Z eff ≈8.92 is approximately seventeen times less sensitive compared to LiF:Mg,Ti (TLD-100). The proposed dosimeter shows good linearity up to 10 3 Gy, minimal fading and photon energy independence. These attractive features offered by our dosimeter is expected to pave the way towards dosimetric applications. - Highlights: • The NH 4 H 2 PO 4 impurities are cross linked with the CuO defect. • The addition of NH 4 H 2 PO 4 as a co-dopant improved the TL intensity by a factor of 3. • The proposed dosimeter shows good linearity up to 10 3 Gy. • Minimal fading and photon energy independence were observed

  16. Intraventricular Injection of LKB1 Inhibits the Formation of Diet-Induced Obesity in Rats by Activating the AMPK-POMC Neurons-Sympathetic Nervous System Axis

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    Pengjiao Xi

    2018-05-01

    Full Text Available Background/Aims: Obesity is increasingly becoming a major public health problem worldwide. Peripheral LKB1 inhibits white fat generation, but the effect of central LKB1 on diet-induced obesity (DIO is unknown. Therefore, we examined whether LKB1 over-expression in the hypothalamus can inhibit the development of obesity. Methods: Adult male Sprague-Dawley rats were anesthetized and placed in a stereotaxic apparatus. LKB1-AAV-EGFP (2.0 × 108 or 2.0 × 1010 vector genomes or Control-AAV-EGFP (2.0 × 108 vector genomes was injected into the third ventricle. After administration, the rats were fed a high-fat diet (HFD for 9 weeks to induce obesity. Rats fed a chow fat diet were used as normal controls. Results: LKB1 delivery decreased body weight, energy intake, fat mass, and serum lipid levels. LKB1 also improved HFD-induced hepatic fatty degeneration. Interestingly, LKB1 over-expression in the hypothalamus activated the AMPK-POMC neurons-sympathetic nervous system (SNS axis, which can release epinephrine to promote white fat browning. Conversely, the elevated expression of MC3R/MC4R inhibited food intake. These two factors worked together to inhibit the development of obesity. Conclusions: LKB1 in the hypothalamus may have therapeutic potential for DIO through the activation of the AMPK-POMC neurons-SNS axis.

  17. Intraventricular Injection of LKB1 Inhibits the Formation of Diet-Induced Obesity in Rats by Activating the AMPK-POMC Neurons-Sympathetic Nervous System Axis.

    Science.gov (United States)

    Xi, Pengjiao; Du, Jianying; Liang, Huimin; Han, Jie; Wu, Zhaoxia; Wang, Haomin; He, Lu; Wang, Qiming; Ge, Haize; Li, Yongmei; Xue, Jie; Tian, Derun

    2018-01-01

    Obesity is increasingly becoming a major public health problem worldwide. Peripheral LKB1 inhibits white fat generation, but the effect of central LKB1 on diet-induced obesity (DIO) is unknown. Therefore, we examined whether LKB1 over-expression in the hypothalamus can inhibit the development of obesity. Adult male Sprague-Dawley rats were anesthetized and placed in a stereotaxic apparatus. LKB1-AAV-EGFP (2.0 × 108 or 2.0 × 1010 vector genomes) or Control-AAV-EGFP (2.0 × 108 vector genomes) was injected into the third ventricle. After administration, the rats were fed a high-fat diet (HFD) for 9 weeks to induce obesity. Rats fed a chow fat diet were used as normal controls. LKB1 delivery decreased body weight, energy intake, fat mass, and serum lipid levels. LKB1 also improved HFD-induced hepatic fatty degeneration. Interestingly, LKB1 over-expression in the hypothalamus activated the AMPK-POMC neurons-sympathetic nervous system (SNS) axis, which can release epinephrine to promote white fat browning. Conversely, the elevated expression of MC3R/MC4R inhibited food intake. These two factors worked together to inhibit the development of obesity. LKB1 in the hypothalamus may have therapeutic potential for DIO through the activation of the AMPK-POMC neurons-SNS axis. © 2018 The Author(s). Published by S. Karger AG, Basel.

  18. LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.

    Science.gov (United States)

    Walsh, Nicole C; Waters, Lynnea R; Fowler, Jessica A; Lin, Mark; Cunningham, Cameron R; Brooks, David G; Rehg, Jerold E; Morse, Herbert C; Teitell, Michael A

    2015-06-01

    T-cell-dependent antigenic stimulation drives the differentiation of B cells into antibody-secreting plasma cells and memory B cells, but how B cells regulate this process is unclear. We show that LKB1 expression in B cells maintains B-cell quiescence and prevents the premature formation of germinal centers (GCs). Lkb1-deficient B cells (BKO) undergo spontaneous B-cell activation and secretion of multiple inflammatory cytokines, which leads to splenomegaly caused by an unexpected expansion of T cells. Within this cytokine response, increased IL-6 production results from heightened activation of NF-κB, which is suppressed by active LKB1. Secreted IL-6 drives T-cell activation and IL-21 production, promoting T follicular helper (TFH ) cell differentiation and expansion to support a ~100-fold increase in steady-state GC B cells. Blockade of IL-6 secretion by BKO B cells inhibits IL-21 expression, a known inducer of TFH -cell differentiation and expansion. Together, these data reveal cell intrinsic and surprising cell extrinsic roles for LKB1 in B cells that control TFH -cell differentiation and GC formation, and place LKB1 as a central regulator of T-cell-dependent humoral immunity. © 2015 The Authors.

  19. The nuclear protein Artemis promotes AMPK activation by stabilizing the LKB1-AMPK complex

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    Nakagawa, Koji, E-mail: k_nakagawa@pharm.hokudai.ac.jp [Department of Pathophysiology and Therapeutics, Division of Pharmascience, Faculty of Pharmaceutical Sciences, Hokkaido University, N12 W6, Kita-ku, Sapporo, Hokkaido 060-0812 (Japan); Uehata, Yasuko; Natsuizaka, Mitsuteru; Kohara, Toshihisa; Darmanin, Stephanie [Department of Gastroenterology and Hematology, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, Hokkaido 060-8638 (Japan); Asaka, Masahiro [Department of Gastroenterology and Hematology, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, Hokkaido 060-8638 (Japan); Department of Cancer Preventive Medicine, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, Hokkaido 060-8638 (Japan); Takeda, Hiroshi [Department of Pathophysiology and Therapeutics, Division of Pharmascience, Faculty of Pharmaceutical Sciences, Hokkaido University, N12 W6, Kita-ku, Sapporo, Hokkaido 060-0812 (Japan); Department of Gastroenterology and Hematology, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, Hokkaido 060-8638 (Japan); Kobayashi, Masanobu [Department of Cancer Preventive Medicine, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, Hokkaido 060-8638 (Japan); School of Nursing and Social Services, Health Sciences University of Hokkaido, Ishikari-Toubetsu, Hokkaido 061-0293 (Japan)

    2012-11-02

    Highlights: Black-Right-Pointing-Pointer The nuclear protein Artemis physically interacts with AMPK{alpha}2. Black-Right-Pointing-Pointer Artemis co-localizes with AMPK{alpha}2 in the nucleus. Black-Right-Pointing-Pointer Artemis promotes phosphorylation and activation of AMPK. Black-Right-Pointing-Pointer The interaction between AMPK{alpha}2 and LKB1 is stabilized by Artemis. -- Abstract: AMP-activated protein kinase (AMPK) is a hetero-trimeric Ser/Thr kinase composed of a catalytic {alpha} subunit and regulatory {beta} and {gamma} subunits; it functions as an energy sensor that controls cellular energy homeostasis. In response to an increased cellular AMP/ATP ratio, AMPK is activated by phosphorylation at Thr172 in the {alpha}-subunit by upstream AMPK kinases (AMPKKs), including tumor suppressor liver kinase B1 (LKB1). To elucidate more precise molecular mechanisms of AMPK activation, we performed yeast two-hybrid screening and isolated the complementary DNA (cDNA) encoding the nuclear protein Artemis/DNA cross-link repair 1C (DCLRE1C) as an AMPK{alpha}2-binding protein. Artemis was found to co-immunoprecipitate with AMPK{alpha}2, and the co-localization of Artemis with AMPK{alpha}2 in the nucleus was confirmed by immunofluorescence staining in U2OS cells. Moreover, over-expression of Artemis enhanced the phosphorylation of AMPK{alpha}2 and the AMPK substrate acetyl-CoA carboxylase (ACC). Conversely, RNAi-mediated knockdown of Artemis reduced AMPK and ACC phosphorylation. In addition, Artemis markedly increased the physical association between AMPK{alpha}2 and LKB1. Taken together, these results suggest that Artemis functions as a positive regulator of AMPK signaling by stabilizing the LKB1-AMPK complex.

  20. Odanacatib Inhibits Resistin-induced Hypertrophic H9c2 Cardiomyoblast Cells Through LKB1/AMPK Pathway

    Directory of Open Access Journals (Sweden)

    Xian Zheng

    2017-08-01

    Full Text Available ABSTRACT Odanacatib (ODN is a selective inhibitor of cathepsin K. The cysteine protease cathepsin K has been implicated in cardiac hypertrophy. Resistine is an adipokine which is identified to promote cardiac hypertrophy. Here, we hypothesize that ODN mitigates resistin-induced myocyte hypertrophy. Cell surface area and protein synthesis were measured after treatment with resistin and ODN in H9c2 cells. The expression of cardiomyocyte hypertrophy marker BNP and β-MHC was detected by RT-qPCR. The expression and phosphorylation of AMPK and LKB1 were analyzed with Western blot. Resistin could significantly increase cardiomyocyte cell surface area, protein synthesis, and embryonic gene BNP and β-MHC expression, inhibit phosphorylation of AMPK and LKB1. ODN could significantly reverse the effects of resistin. Collectively, our data suggest that ODN can inhibit cardiomyocyte hypertrophy induced by resistin and the underlying mechanism may be involved in LKB1/AMPK pathway.

  1. The nuclear protein Artemis promotes AMPK activation by stabilizing the LKB1–AMPK complex

    International Nuclear Information System (INIS)

    Nakagawa, Koji; Uehata, Yasuko; Natsuizaka, Mitsuteru; Kohara, Toshihisa; Darmanin, Stephanie; Asaka, Masahiro; Takeda, Hiroshi; Kobayashi, Masanobu

    2012-01-01

    Highlights: ► The nuclear protein Artemis physically interacts with AMPKα2. ► Artemis co-localizes with AMPKα2 in the nucleus. ► Artemis promotes phosphorylation and activation of AMPK. ► The interaction between AMPKα2 and LKB1 is stabilized by Artemis. -- Abstract: AMP-activated protein kinase (AMPK) is a hetero-trimeric Ser/Thr kinase composed of a catalytic α subunit and regulatory β and γ subunits; it functions as an energy sensor that controls cellular energy homeostasis. In response to an increased cellular AMP/ATP ratio, AMPK is activated by phosphorylation at Thr172 in the α-subunit by upstream AMPK kinases (AMPKKs), including tumor suppressor liver kinase B1 (LKB1). To elucidate more precise molecular mechanisms of AMPK activation, we performed yeast two-hybrid screening and isolated the complementary DNA (cDNA) encoding the nuclear protein Artemis/DNA cross-link repair 1C (DCLRE1C) as an AMPKα2-binding protein. Artemis was found to co-immunoprecipitate with AMPKα2, and the co-localization of Artemis with AMPKα2 in the nucleus was confirmed by immunofluorescence staining in U2OS cells. Moreover, over-expression of Artemis enhanced the phosphorylation of AMPKα2 and the AMPK substrate acetyl-CoA carboxylase (ACC). Conversely, RNAi-mediated knockdown of Artemis reduced AMPK and ACC phosphorylation. In addition, Artemis markedly increased the physical association between AMPKα2 and LKB1. Taken together, these results suggest that Artemis functions as a positive regulator of AMPK signaling by stabilizing the LKB1–AMPK complex.

  2. LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats and effects of training.

    Science.gov (United States)

    Sriwijitkamol, Apiradee; Ivy, John L; Christ-Roberts, Christine; DeFronzo, Ralph A; Mandarino, Lawrence J; Musi, Nicolas

    2006-05-01

    AMPK is a key regulator of fat and carbohydrate metabolism. It has been postulated that defects in AMPK signaling could be responsible for some of the metabolic abnormalities of type 2 diabetes. In this study, we examined whether insulin-resistant obese Zucker rats have abnormalities in the AMPK pathway. We compared AMPK and ACC phosphorylation and the protein content of the upstream AMPK kinase LKB1 and the AMPK-regulated transcriptional coactivator PPARgamma coactivator-1 (PGC-1) in gastrocnemius of sedentary obese Zucker rats and sedentary lean Zucker rats. We also examined whether 7 wk of exercise training on a treadmill reversed abnormalities in the AMPK pathway in obese Zucker rats. In the obese rats, AMPK phosphorylation was reduced by 45% compared with lean rats. Protein expression of the AMPK kinase LKB1 was also reduced in the muscle from obese rats by 43%. In obese rats, phosphorylation of ACC and protein expression of PGC-1alpha, two AMPK-regulated proteins, tended to be reduced by 50 (P = 0.07) and 35% (P = 0.1), respectively. There were no differences in AMPKalpha1, -alpha2, -beta1, -beta2, and -gamma3 protein content between lean and obese rats. Training caused a 1.5-fold increase in AMPKalpha1 protein content in the obese rats, although there was no effect of training on AMPK phosphorylation and the other AMPK isoforms. Furthermore, training also significantly increased LKB1 and PGC-1alpha protein content 2.8- and 2.5-fold, respectively, in the obese rats. LKB1 protein strongly correlated with hexokinase II activity (r = 0.75, P = 0.001), citrate synthase activity (r = 0.54, P = 0.02), and PGC-1alpha protein content (r = 0.81, P < 0.001). In summary, obese insulin-resistant rodents have abnormalities in the LKB1-AMPK-PGC-1 pathway in muscle, and these abnormalities can be restored by training.

  3. Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.

    NARCIS (Netherlands)

    Forcet, C.; Etienne-Manneville, S.; Gaude, H.; Fournier, L.; Debilly, S.; Salmi, M.; Baas, A.; Olschwang, S.; Clevers, J.C.; Billaud, M.

    2005-01-01

    Germline mutations of the LKB1 gene are responsible for the cancer-prone Peutz-Jeghers syndrome (PJS). LKB1 encodes a serine-threonine kinase that acts as a regulator of cell cycle, metabolism and cell polarity. The majority of PJS missense mutations abolish LKB1 enzymatic activity and thereby

  4. ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor.

    Directory of Open Access Journals (Sweden)

    Elton Zeqiraj

    2009-06-01

    Full Text Available Pseudokinases lack essential residues for kinase activity, yet are emerging as important regulators of signal transduction networks. The pseudokinase STRAD activates the LKB1 tumour suppressor by forming a heterotrimeric complex with LKB1 and the scaffolding protein MO25. Here, we describe the structure of STRADalpha in complex with MO25alpha. The structure reveals an intricate web of interactions between STRADalpha and MO25alpha involving the alphaC-helix of STRADalpha, reminiscent of the mechanism by which CDK2 interacts with cyclin A. Surprisingly, STRADalpha binds ATP and displays a closed conformation and an ordered activation loop, typical of active protein kinases. Inactivity is accounted for by nonconservative substitution of almost all essential catalytic residues. We demonstrate that binding of ATP enhances the affinity of STRADalpha for MO25alpha, and conversely, binding of MO25alpha promotes interaction of STRADalpha with ATP. Mutagenesis studies reveal that association of STRADalpha with either ATP or MO25alpha is essential for LKB1 activation. We conclude that ATP and MO25alpha cooperate to maintain STRADalpha in an "active" closed conformation required for LKB1 activation. It has recently been demonstrated that a mutation in human STRADalpha that truncates a C-terminal region of the pseudokinase domain leads to the polyhydramnios, megalencephaly, symptomatic epilepsy (PMSE syndrome. We demonstrate this mutation destabilizes STRADalpha and prevents association with LKB1. In summary, our findings describe one of the first structures of a genuinely inactive pseudokinase. The ability of STRADalpha to activate LKB1 is dependent on a closed "active" conformation, aided by ATP and MO25alpha binding. Thus, the function of STRADalpha is mediated through an active kinase conformation rather than kinase activity. It is possible that other pseudokinases exert their function through nucleotide binding and active conformations.

  5. 3D view to tumor suppression: Lkb1, polarity and the arrest of oncogenic c-Myc.

    Science.gov (United States)

    Partanen, Johanna I; Nieminen, Anni I; Klefstrom, Juha

    2009-03-01

    Machiavelli wrote, in his famous political treatise Il Principe, about disrupting organization by planting seeds of dissension or by eliminating necessary support elements. Tumor cells do exactly that by disrupting the organized architecture of epithelial cell layers during progression from contained benign tumor to full-blown invasive cancer. However, it is still unclear whether tumor cells primarily break free by activating oncogenes powerful enough to cause chaos or by eliminating tumor suppressor genes guarding the order of the epithelial organization. Studies in Drosophila have exposed genes that encode key regulators of the epithelial apicobasal polarity and which, upon inactivation, cause disorganization of the epithelial layers and promote unscheduled cell proliferation. These polarity regulator/tumor suppressor proteins, which include products of neoplastic tumor suppressor genes (nTSGs), are carefully positioned in polarized epithelial cells to maintain the order of epithelial structures and to impose a restraint on cell proliferation. In this review, we have explored the presence and prevalence of somatic mutations in the human counterparts of Drosophila polarity regulator/tumor suppressor genes across the human cancers. The screen points out LKB1, which is a causal genetic lesion in Peutz-Jeghers cancer syndrome, a gene mutated in certain sporadic cancers and a human homologue of the fly polarity gene par-4. We review the evidence linking Lkb1 protein to polarity regulation in the scope of our recent results suggesting a coupled role for Lkb1 as an architect of organized acinar structures and a suppressor of oncogenic c-Myc. We finally present models to explain how Lkb1-dependent formation of epithelial architecture is coupled to suppression of normal and oncogene-induced proliferation.

  6. Investigating Cooperation between KEAP1 and LKB1 Inactivation in Lung Adenocarcinoma

    Science.gov (United States)

    2017-08-01

    The tumor suppressor LKB1 kinase directly activates AMP -activated kinase and regulates apoptosis in response to energy stress. Proc Natl Acad Sci USA...Nrf2 signaling pathway. The international journal of biochemistry & cell biology 38, 317-332, doi:10.1016/j.biocel.2005.09.018 (2006). 24. Cullinan

  7. Resource programs: Draft Environmental Impact Statement Resource Programs

    International Nuclear Information System (INIS)

    1992-03-01

    Every two years, Bonneville Power Administration (BPA) prepares a Resource Program which identifies the resource actions BPA will take to meet its obligation to serve the forecasted power requirements of its customers. The Resource Program's Environmental Impact Statement (RPEIS) is a programmatic environmental document which will support decisions made in several future Resource Programs. Environmental documents tiered to the EIS may be prepared on a site-specific basis. The RPEIS includes a description of the environmental effects and mitigation for the various resource types available in order to evaluate the trade-offs among them. It also assesses the environmental impacts of adding thirteen alternative combinations of resources to the existing power system. This report contains the appendices to the RPEIS

  8. Xanthene derivatives increase glucose utilization through activation of LKB1-dependent AMP-activated protein kinase.

    Directory of Open Access Journals (Sweden)

    Yonghoon Kwon

    Full Text Available 5' AMP-activated protein kinase (AMPK is a highly conserved serine-threonine kinase that regulates energy expenditure by activating catabolic metabolism and suppressing anabolic pathways to increase cellular energy levels. Therefore AMPK activators are considered to be drug targets for treatment of metabolic diseases such as diabetes mellitus. To identify novel AMPK activators, we screened xanthene derivatives. We determined that the AMPK activators 9H-xanthene-9-carboxylic acid {2,2,2-trichloro-1-[3-(3-nitro-phenyl-thioureido]-ethyl}-amide (Xn and 9H-xanthene-9-carboxylic acid {2,2,2-trichloro-1-[3-(3-cyano-phenyl-thioureido]-ethyl}-amide (Xc elevated glucose uptake in L6 myotubes by stimulating translocation of glucose transporter type 4 (GLUT4. Treatment with the chemical AMPK inhibitor compound C and infection with dominant-negative AMPKa2-virus inhibited AMPK phosphorylation and glucose uptake in myotubes induced by either Xn or Xc. Of the two major upstream kinases of AMPK, we found that Xn and Xc showed LKB1 dependency by knockdown of STK11, an ortholog of human LKB1. Single intravenous administration of Xn and Xc to high-fat diet-induced diabetic mice stimulated AMPK phosphorylation of skeletal muscle and improved glucose tolerance. Taken together, these results suggest that Xn and Xc regulate glucose homeostasis through LKB1-dependent AMPK activation and that the compounds are potential candidate drugs for the treatment of type 2 diabetes mellitus.

  9. Dosimetric Characteristics of a LKB:Cu,Mg Solid Thermoluminescence Detector

    International Nuclear Information System (INIS)

    Alajerami Yasser Saleh Mustafa; Hashim Suhairul; Ramli Ahmad Termizi; Saleh Muneer Aziz; Kadir Ahmad Bazlie Bin Abdul; Saripan, Mohd. Iqbal

    2013-01-01

    We present the main thermoluminescence characteristics of a newly borate glass dosimeter modified with lithium and potassium carbonate (LKB) and co-doped with CuO and MgO. An enhancement of about three times has been shown with the increment of 0.1mol% MgO as a co-dopant impurity. The effects of dose linearity, storage capacity, effective atomic number and energy dose response are studied. The proposed dosimeter shows a simple glow curve, good linearity up to 10 3 Gy, close effective atomic number and photon energy independence. The current results suggest using the proposed dosimeter in different dosimetric applications

  10. Draft 1992 Resource Program : Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-01-01

    The 1992 Resource Program will propose actions to meet future loads placed on the Bonneville Power Administration (BPA). It will also discuss and attempt to resolve resource-related policy issues. The Resource Program assesses resource availability and costs, and analyzes resource requirements and alternative ways of meeting those requirements through both conservation and generation resources. These general resource conclusions are then translated to actions for both conservation and generation. The Resource Program recommends budgets for the Office of Energy Resources for Fiscal Years (FY) 1994 and 1995. BPA's Resource Program bears directly on an important BPA responsibility: the obligation under the Northwest Power Act{sup 3} to meet the power requirements of public and private utility and direct service industrial (DSI) customers according to their contractual agreements. BPA's Draft 1992 Resource Program is contained in four documents: (1) 1992 Resource Program Summary; (2) Technical Report; (3) Technical Assumptions Appendix; and, (4) Conservation Implementation Plan. This volume is the Draft 1992 Resource Program Technical Report, a comprehensive document that provides supporting data and analyses for Resource Program recommendations.

  11. Draft 1992 Resource Program : Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-01-01

    The 1992 Resource Program will propose actions to meet future loads placed on the Bonneville Power Administration (BPA). It will also discuss and attempt to resolve resource-related policy issues. The Resource Program assesses resource availability and costs, and analyzes resource requirements and alternative ways of meeting those requirements through both conservation and generation resources. These general resource conclusions are then translated to actions for both conservation and generation. The Resource Program recommends budgets for the Office of Energy Resources for Fiscal Years (FY) 1994 and 1995. BPA`s Resource Program bears directly on an important BPA responsibility: the obligation under the Northwest Power Act{sup 3} to meet the power requirements of public and private utility and direct service industrial (DSI) customers according to their contractual agreements. BPA`s Draft 1992 Resource Program is contained in four documents: (1) 1992 Resource Program Summary; (2) Technical Report; (3) Technical Assumptions Appendix; and, (4) Conservation Implementation Plan. This volume is the Draft 1992 Resource Program Technical Report, a comprehensive document that provides supporting data and analyses for Resource Program recommendations.

  12. LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons.

    Science.gov (United States)

    Kwon, Seok-Kyu; Sando, Richard; Lewis, Tommy L; Hirabayashi, Yusuke; Maximov, Anton; Polleux, Franck

    2016-07-01

    Individual synapses vary significantly in their neurotransmitter release properties, which underlie complex information processing in neural circuits. Presynaptic Ca2+ homeostasis plays a critical role in specifying neurotransmitter release properties, but the mechanisms regulating synapse-specific Ca2+ homeostasis in the mammalian brain are still poorly understood. Using electrophysiology and genetically encoded Ca2+ sensors targeted to the mitochondrial matrix or to presynaptic boutons of cortical pyramidal neurons, we demonstrate that the presence or absence of mitochondria at presynaptic boutons dictates neurotransmitter release properties through Mitochondrial Calcium Uniporter (MCU)-dependent Ca2+ clearance. We demonstrate that the serine/threonine kinase LKB1 regulates MCU expression, mitochondria-dependent Ca2+ clearance, and thereby, presynaptic release properties. Re-establishment of MCU-dependent mitochondrial Ca2+ uptake at glutamatergic synapses rescues the altered neurotransmitter release properties characterizing LKB1-null cortical axons. Our results provide novel insights into the cellular and molecular mechanisms whereby mitochondria control neurotransmitter release properties in a bouton-specific way through presynaptic Ca2+ clearance.

  13. Clinical validation of the LKB model and parameter sets for predicting radiation-induced pneumonitis from breast cancer radiotherapy

    International Nuclear Information System (INIS)

    Tsougos, Ioannis; Mavroidis, Panayiotis; Theodorou, Kyriaki; Rajala, J; Pitkaenen, M A; Holli, K; Ojala, A T; Hyoedynmaa, S; Jaervenpaeae, Ritva; Lind, Bengt K; Kappas, Constantin

    2006-01-01

    The choice of the appropriate model and parameter set in determining the relation between the incidence of radiation pneumonitis and dose distribution in the lung is of great importance, especially in the case of breast radiotherapy where the observed incidence is fairly low. From our previous study based on 150 breast cancer patients, where the fits of dose-volume models to clinical data were estimated (Tsougos et al 2005 Evaluation of dose-response models and parameters predicting radiation induced pneumonitis using clinical data from breast cancer radiotherapy Phys. Med. Biol. 50 3535-54), one could get the impression that the relative seriality is significantly better than the LKB NTCP model. However, the estimation of the different NTCP models was based on their goodness-of-fit on clinical data, using various sets of published parameters from other groups, and this fact may provisionally justify the results. Hence, we sought to investigate further the LKB model, by applying different published parameter sets for the very same group of patients, in order to be able to compare the results. It was shown that, depending on the parameter set applied, the LKB model is able to predict the incidence of radiation pneumonitis with acceptable accuracy, especially when implemented on a sub-group of patients (120) receiving D-bar-bar vertical bar EUD higher than 8 Gy. In conclusion, the goodness-of-fit of a certain radiobiological model on a given clinical case is closely related to the selection of the proper scoring criteria and parameter set as well as to the compatibility of the clinical case from which the data were derived. (letter to the editor)

  14. Ursolic acid inhibits adipogenesis in 3T3-L1 adipocytes through LKB1/AMPK pathway.

    Directory of Open Access Journals (Sweden)

    Yonghan He

    Full Text Available BACKGROUND: Ursolic acid (UA is a triterpenoid compound with multiple biological functions. This compound has recently been reported to possess an anti-obesity effect; however, the mechanisms are less understood. OBJECTIVE: As adipogenesis plays a critical role in obesity, the present study was conducted to investigate the effect of UA on adipogenesis and mechanisms of action in 3T3-L1 preadipocytes. METHODS AND RESULTS: The 3T3-L1 preadipocytes were induced to differentiate in the presence or absence of UA for 6 days. The cells were determined for proliferation, differentiation, fat accumulation as well as the protein expressions of molecular targets that regulate or are involved in fatty acid synthesis and oxidation. The results demonstrated that ursolic acid at concentrations ranging from 2.5 µM to 10 µM dose-dependently attenuated adipogenesis, accompanied by reduced protein expression of CCAAT element binding protein β (C/EBPβ, peroxisome proliferator-activated receptor γ (PPARγ, CCAAT element binding protein α (C/EBPα and sterol regulatory element binding protein 1c (SREBP-1c, respectively. Ursolic acid increased the phosphorylation of acetyl-CoA carboxylase (ACC and protein expression of carnitine palmitoyltransferase 1 (CPT1, but decreased protein expression of fatty acid synthase (FAS and fatty acid-binding protein 4 (FABP4. Ursolic acid increased the phosphorylation of AMP-activated protein kinase (AMPK and protein expression of (silent mating type information regulation 2, homolog 1 (Sirt1. Further studies demonstrated that the anti-adipogenic effect of UA was reversed by the AMPK siRNA, but not by the Sirt1 inhibitor nicotinamide. Liver kinase B1 (LKB1, the upstream kinase of AMPK, was upregulated by UA. When LKB1 was silenced with siRNA or the inhibitor radicicol, the effect of UA on AMPK activation was diminished. CONCLUSIONS: Ursolic acid inhibited 3T3-L1 preadipocyte differentiation and adipogenesis through the LKB1/AMPK

  15. Natural resources youth training program (NRYTP), resource rangers 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-09-15

    In 2010, for a second year, the natural resources youth training program (NRYTP) was developed in northern Manitoba thanks to Manitoba Keewatinowi Okimakanak Inc. (MKO) and the collaboration of 42 sponsors. 16 aboriginal youth representing six northern communities took part in the five-week program located at the Egg Lake camp. The objective was to provide these resources rangers with knowledge and training in the most widespread resource sectors in northern Manitoba, including mining, forestry and hydropower. Trainers and experts provided by industry partners offered training sessions, hands-on work experience and other activities to help resource rangers to acquire a better understanding of the employability in this field in the northern region and the knowledge and skills the resource-based careers require. Life and professional skills training was given by the camp staff and local professionals. On-site elders and cultural events also allowed the integration of a northern Cree cultural component. Three staff members, a cook and elders assisted daily the resource rangers. Many improvements and refinements have been made since the success of the 2009 program, including the involvement of a larger number of communities, program contributors and program graduates. The program length has doubled and the number of jobs created has increased, important cultural aspects were introduced and the overall expenses were reduced.

  16. NASA Water Resources Program

    Science.gov (United States)

    Toll, David L.

    2011-01-01

    With increasing population pressure and water usage coupled with climate variability and change, water issues are being reported by numerous groups as the most critical environmental problems facing us in the 21st century. Competitive uses and the prevalence of river basins and aquifers that extend across boundaries engender political tensions between communities, stakeholders and countries. In addition to the numerous water availability issues, water quality related problems are seriously affecting human health and our environment. The potential crises and conflicts especially arise when water is competed among multiple uses. For example, urban areas, environmental and recreational uses, agriculture, and energy production compete for scarce resources, not only in the Western U.S. but throughout much of the U.S. and also in numerous parts of the world. Mitigating these conflicts and meeting water demands and needs requires using existing water resources more efficiently. The NASA Water Resources Program Element works to use NASA products and technology to address these critical water issues. The primary goal of the Water Resources is to facilitate application of NASA Earth science products as a routine use in integrated water resources management for the sustainable use of water. This also includes the extreme events of drought and floods and the adaptation to the impacts from climate change. NASA satellite and Earth system observations of water and related data provide a huge volume of valuable data in both near-real-time and extended back nearly 50 years about the Earth's land surface conditions such as precipitation, snow, soil moisture, water levels, land cover type, vegetation type, and health. NASA Water Resources Program works closely to use NASA and Earth science data with other U.S. government agencies, universities, and non-profit and private sector organizations both domestically and internationally. The NASA Water Resources Program organizes its

  17. Draft 1992 Resource Program : Summary Report.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-01-01

    The Resource Program is the Bonneville Power Administration's primary process for deciding how to meet future resource needs -- how much new resource development is needed by BPA, which types of resources to acquire and option, how to go about acquiring them, and how much to spend. The Northwest Power Planning Council completed a new Northwest Power Plan in 1991. This Draft Resource Program describes how BPA proposes to do its part to meet the Council's regional resource objectives.

  18. Animal Resource Program | Center for Cancer Research

    Science.gov (United States)

    CCR Animal Resource Program The CCR Animal Resource Program plans, develops, and coordinates laboratory animal resources for CCR’s research programs. We also provide training, imaging, and technology development in support of moving basic discoveries to the clinic. The ARP Manager:

  19. Animal Resource Program | Center for Cancer Research

    Science.gov (United States)

    CCR Animal Resource Program The CCR Animal Resource Program plans, develops, and coordinates laboratory animal resources for CCR’s research programs. We also provide training, imaging, and technology development in support of moving basic discoveries to the clinic. The ARP Office:

  20. 1992 Resource Program, 10 Year Plan : Draft II.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-05-01

    The Resource Program is the Bonneville Power Administration's primary process for deciding how to meet future electricity resource needs, how much new resources to develop, which types of resources to acquire or option and how to go about acquiring them, and how much BPA will have to spend for these resources. Recognizing that BPA must make a long-term commitment to acquiring conservation effectively, the 1992 Resource Program outlines a 10-year plan. Draft 2 of the 1992 Resource Program provides a framework for discussing the funding levels proposed in the Programs in Perspective (PIP) process. Previous final resource programs have been released prior to the PIP process. This version of the Resource Program recognizes that the PIP discussions are an integral part of the resource decision-making process and, therefore, it will be finalized after PIP.

  1. 1992 Resource Program, 10 Year Plan : Draft II.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-05-01

    The Resource Program is the Bonneville Power Administration`s primary process for deciding how to meet future electricity resource needs, how much new resources to develop, which types of resources to acquire or option and how to go about acquiring them, and how much BPA will have to spend for these resources. Recognizing that BPA must make a long-term commitment to acquiring conservation effectively, the 1992 Resource Program outlines a 10-year plan. Draft 2 of the 1992 Resource Program provides a framework for discussing the funding levels proposed in the Programs in Perspective (PIP) process. Previous final resource programs have been released prior to the PIP process. This version of the Resource Program recognizes that the PIP discussions are an integral part of the resource decision-making process and, therefore, it will be finalized after PIP.

  2. Resource Programs: Final Environmental Impact Statement

    International Nuclear Information System (INIS)

    1993-02-01

    Every two years, BA prepares a Resource Program, which identifies the resource actions BA will take to meet its obligation to serve the forecasted power requirements of its customers. The Resource Programs Environmental Impact Statement (RPEIS) is a programmatic environmental document that will support decisions made in several future Resource Programs. Environmental documents tiered to this EIS may be prepared on a site-specific basis. The RPEIS includes a description of the environmental effects and mitigation for the various resource types available in order to evaluate the trade-offs among them. It also assesses the environmental impacts of adding thirteen alternative combinations of resources to the existing power system. The alternatives represent the range of actions BA could take to meet its load obligations. Each of the alternatives allows BA to meet the almost 5,000 average megawatt load increase that could occur with high load growth, or an equivalent need for resources caused by a combination of load growth and any future loss of resources

  3. Bridge resource program.

    Science.gov (United States)

    2013-09-01

    The mission of Rutgers Universitys Center for Advanced Infrastructure and Transportation (CAIT) Bridge Resource Program (BRP) is to provide bridge engineering support to the New Jersey Department of Transportation (NJDOT)s Bridge Engineering an...

  4. Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway.

    Science.gov (United States)

    Li, Xian; Park, Soon Jin; Jin, Fansi; Deng, Yifeng; Yang, Ju Hye; Chang, Jae-Hoon; Kim, Dong-Young; Kim, Jung-Ae; Lee, Youn Ju; Murakami, Makoto; Son, Kun Ho; Chang, Hyeun Wook

    2018-06-01

    AMP-activated protein kinase (AMPK) and its upstream mediators liver kinase B1 (LKB1) and sirtuin 1 (Sirt1) are generally known as key regulators of metabolism. We have recently reported that the AMPK pathway negatively regulates mast cell activation and anaphylaxis. Tanshinone IIA (Tan IIA), an active component of Salvia miltiorrhiza extract that is currently used for the treatment of cardiovascular and cerebrovascular diseases, shows anti-diabetic activity and improves insulin resistance in db/db mice through activation of AMPK. The aim of this study was to evaluate the anti-allergic activity of Tan IIA in vivo and to investigate the underlying mechanism in vitro in the context of AMPK signaling. The anti-allergic effect of Tan IIA was evaluated using mouse bone marrow-derived mast cells (BMMCs) from AMPKα2 -/- or Sirt1 -/- mice, or BMMCs transfected with siRNAs specific for AMPKα2, LKB1, or Sirt1. AMPKα2 -/- and Sirt1 -/- mice were used to confirm the anti-allergic effect of Tan IIA in anaphylaxis in vivo. Tan IIA dose-dependently inhibited FcεRI-mediated degranulation and production of eicosanoids and cytokines in BMMCs. These inhibitory effects were diminished by siRNA-mediated knockdown or genetic deletion of AMPKα2 or Sirt1. Moreover, Tan IIA inhibited a mast cell-mediated local passive anaphylactic reaction in wild-type mice, but not in AMPKα2 -/- or Sirt1 -/- mice. In conclusion, Tan IIA suppresses FcεRI-mediated mast cell activation and anaphylaxis through activation of the inhibitory Sirt1-LKB1-AMPK pathway. Thus, Tan IIA may be useful as a new therapeutic agent for mast cell-mediated allergic diseases. Copyright © 2018 Elsevier Inc. All rights reserved.

  5. Probabilistic Resource Analysis by Program Transformation

    DEFF Research Database (Denmark)

    Kirkeby, Maja Hanne; Rosendahl, Mads

    2016-01-01

    The aim of a probabilistic resource analysis is to derive a probability distribution of possible resource usage for a program from a probability distribution of its input. We present an automated multi-phase rewriting based method to analyze programs written in a subset of C. It generates...

  6. Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.

    Science.gov (United States)

    Lee, Jihyun; Yang, Goowon; Kim, Young-Joo; Tran, Quynh Hoa; Choe, Wonchae; Kang, Insug; Kim, Sung Soo; Ha, Joohun

    2017-09-23

    Persistent oxidative stress is recognized as a major cause of many pathological conditions as well as ageing. However, most clinical trials of dietary antioxidants have failed to produce successful outcomes in treating oxidative stress-induced diseases. Molecular hydrogen (H 2 ) has recently received considerable attention as a therapeutic agent owing to its novel antioxidant properties, a selective scavenger of hydroxyl and peroxynitrite radicals. Beyond this, numerous reports support that H 2 can modulate the activity of various cellular signal pathways. However, its effect on AMP-activated protein kinase (AMPK) signal pathway, a central regulator of energy hemostasis, has remained almost elusive. Here, we report that hydrogen-rich medium activated LKB1-AMPK signal pathway without ATP depletion, which in turn induced FoxO1-dependent transcription of manganese superoxide dismutase and catalase in mouse embryonic fibroblasts. Moreover, hydrogen-rich media effectively reduced the level of reactive oxygen species in cells treated with hydrogen peroxide and protected these cells from apoptosis in an AMPK-dependent manner. These results suggest that the LKB1-AMPK-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H 2 , further supporting the idea that H 2 acts as a signaling molecule to serve various physiological functions. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. A Novel Hydroxamate-Based Compound WMJ-J-09 Causes Head and Neck Squamous Cell Carcinoma Cell Death via LKB1-AMPK-p38MAPK-p63-Survivin Cascade.

    Science.gov (United States)

    Yen, Chia-Sheng; Choy, Cheuk-Sing; Huang, Wei-Jan; Huang, Shiu-Wen; Lai, Pin-Ye; Yu, Meng-Chieh; Shiue, Ching; Hsu, Ya-Fen; Hsu, Ming-Jen

    2018-01-01

    Growing evidence shows that hydroxamate-based compounds exhibit broad-spectrum pharmacological properties including anti-tumor activity. However, the precise mechanisms underlying hydroxamate derivative-induced cancer cell death remain incomplete understood. In this study, we explored the anti-tumor mechanisms of a novel aliphatic hydroxamate-based compound, WMJ-J-09, in FaDu head and neck squamous cell carcinoma (HNSCC) cells. WMJ-J-09 induced G2/M cell cycle arrest and apoptosis in FaDu cells. These actions were associated with liver kinase B1 (LKB1), AMP-activated protein kinase (AMPK) and p38 mitogen-activated protein kinase (p38MAPK) activation, transcription factor p63 phosphorylation, as well as modulation of p21 and survivin. LKB1-AMPK-p38MAPK signaling blockade reduced WMJ-J-09's enhancing effects in p63 phosphorylation, p21 elevation and survivin reduction. Moreover, WMJ-J-09 caused an increase in α-tubulin acetylation and interfered with microtubule assembly. Furthermore, WMJ-J-09 suppressed the growth of subcutaneous FaDu xenografts in vivo . Taken together, WMJ-J-09-induced FaDu cell death may involve LKB1-AMPK-p38MAPK-p63-survivin signaling cascade. HDACs inhibition and disruption of microtubule assembly may also contribute to WMJ-J-09's actions in FaDu cells. This study suggests that WMJ-J-09 may be a potential lead compound and warrant the clinical development in the treatment of HNSCC.

  8. Otolaryngology Residency Program Research Resources and Scholarly Productivity.

    Science.gov (United States)

    Villwock, Jennifer A; Hamill, Chelsea S; Nicholas, Brian D; Ryan, Jesse T

    2017-06-01

    Objective To delineate research resources available to otolaryngology residents and their impact on scholarly productivity. Study Design Survey of current otolaryngology program directors. Setting Otolaryngology residency programs. Subjects and Methods An anonymous web-based survey was sent to 98 allopathic otolaryngology training program directors. Fisher exact tests and nonparametric correlations were used to determine statistically significant differences among various strata of programs. Results Thirty-nine percent (n = 38) of queried programs responded. Fourteen (37%) programs had 11 to 15 full-time, academic faculty associated with the residency program. Twenty (53%) programs have a dedicated research coordinator. Basic science lab space and financial resources for statistical work were present at 22 programs (58%). Funding is uniformly provided for presentation of research at conferences; a minority of programs (13%) only funded podium presentations. Twenty-four (63%) have resident research requirements beyond the Accreditation Council for Graduate Medical Education (ACGME) mandate of preparing a "manuscript suitable for publication" prior to graduation. Twenty-five (67%) programs have residents with 2 to 3 active research projects at any given time. None of the investigated resources were significantly associated with increased scholarly output. There was no uniformity to research curricula. Conclusions Otolaryngology residency programs value research, evidenced by financial support provided and requirements beyond the ACGME minimum. Additional resources were not statistically related to an increase in resident research productivity, although they may contribute positively to the overall research experience during training. Potential future areas to examine include research curricula best practices, how to develop meaningful mentorship and resource allocation that inspires continued research interest, and intellectual stimulation.

  9. Nurture of human resources for geological repository program

    International Nuclear Information System (INIS)

    Fujiwara, A.

    2004-01-01

    The Japanese geological repository program entered the implementing stage in 2002. At the implementing stage of the program, different sectors need various human resources to conduct their functions. This paper discusses a suitable framework of nurture of the human resources to progress the geological repository program. The discussion is based on considering of specific characters involved in the program and of the multidisciplinary knowledge related to geological disposal. Considering the specific characters of the project, two types of the human resources need to be nurtured. First type is the core persons with the highest knowledge on geological disposal. They are expected to communicate with the various stakeholders and pass down the whole knowledge of the project to the next generation. Another is to conduct the project as the managers, the engineers and the workers. The former human resources can be developed through the broad practice and experience in each sector. The latter human resources can be effectively developed by training of the fundamental knowledge on geological disposal at training centers as well as by conventional on-the-job training. The sectors involved in the program need to take their own roles in the nurture of these human resources. (author)

  10. Resource Programs : Draft Environmental Impact Statement, Volume 2, Appendices.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-03-01

    Every two years, Bonneville Power Administration (BPA) prepares a Resource Program which identifies the resource actions BPA will take to meet its obligation to serve the forecasted power requirements of its customers. The Resource Program`s Environmental Impact Statement (RPEIS) is a programmatic environmental document which will support decisions made in several future Resource Programs. Environmental documents tiered to the EIS may be prepared on a site-specific basis. The RPEIS includes a description of the environmental effects and mitigation for the various resource types available in order to evaluate the trade-offs among them. It also assesses the environmental impacts of adding thirteen alternative combinations of resources to the existing power system. This report contains the appendices to the RPEIS.

  11. N-n-butyl haloperidol iodide ameliorates hypoxia/reoxygenation injury through modulating the LKB1/AMPK/ROS pathway in cardiac microvascular endothelial cells.

    Science.gov (United States)

    Lu, Binger; Wang, Bin; Zhong, Shuping; Zhang, Yanmei; Gao, Fenfei; Chen, Yicun; Zheng, Fuchun; Shi, Ganggang

    2016-06-07

    Endothelial cells are highly sensitive to hypoxia and contribute to myocardial ischemia/reperfusion injury. We have reported that N-n-butyl haloperidol iodide (F2) can attenuate hypoxia/reoxygenation (H/R) injury in cardiac microvascular endothelial cells (CMECs). However, the molecular mechanisms remain unclear. Neonatal rat CMECs were isolated and subjected to H/R. Pretreatment of F2 leads to a reduction in H/R injury, as evidenced by increased cell viability, decreased lactate dehydrogenase (LDH) leakage and apoptosis, together with enhanced AMP-activated protein kinase (AMPK) and liver kinase B1 (LKB1) phosphorylation in H/R ECs. Blockade of AMPK with compound C reversed F2-induced inhibition of H/R injury, as evidenced by decreased cell viability, increased LDH release and apoptosis. Moreover, compound C also blocked the ability of F2 to reduce H/R-induced reactive oxygen species (ROS) generation. Supplementation with the ROS scavenger N-acetyl-L-cysteine (NAC) reduced ROS levels, increased cell survival rate, and decreased both LDH release and apoptosis after H/R. In conclusion, our data indicate that F2 may mitigate H/R injury by stimulating LKB1/AMPK signaling pathway and subsequent suppression of ROS production in CMECs.

  12. Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats.

    Science.gov (United States)

    Jiang, Shu-Jun; Dong, Hui; Li, Jing-Bin; Xu, Li-Jun; Zou, Xin; Wang, Kai-Fu; Lu, Fu-Er; Yi, Ping

    2015-07-07

    To investigate the molecular mechanisms of berberine inhibition of hepatic gluconeogenesis in a diabetic rat model. The 40 rats were randomly divided into five groups. One group was selected as the normal group. In the remaining groups (n = 8 each), the rats were fed on a high-fat diet for 1 mo and received intravenous injection of streptozotocin for induction of the diabetic models. Berberine (156 mg/kg per day) (berberine group) or metformin (184 mg/kg per day) (metformin group) was intragastrically administered to the diabetic rats and 5-aminoimidazole-4-carboxamide1-β-D-ribofuranoside (AICAR) (0.5 mg/kg per day) (AICAR group) was subcutaneously injected to the diabetic rats for 12 wk. The remaining eight diabetic rats served as the model group. Fasting plasma glucose and insulin levels as well as lipid profile were tested. The expressions of proteins were examined by western blotting. The nuclear translocation of CREB-regulated transcription co-activator (TORC)2 was observed by immunohistochemical staining. Berberine improved impaired glucose tolerance and decreased plasma hyperlipidemia. Moreover, berberine decreased fasting plasma insulin and homeostasis model assessment of insulin resistance (HOMA-IR). Berberine upregulated protein expression of liver kinase (LK)B1, AMP-activated protein kinase (AMPK) and phosphorylated AMPK (p-AMPK). The level of phophorylated TORC2 (p-TORC2) protein in the cytoplasm was higher in the berberine group than in the model group, and no significant difference in total TORC2 protein level was observed. Immunohistochemical staining revealed that more TORC2 was localized in the cytoplasm of the berberine group than in the model group. Moreover, berberine treatment downregulated protein expression of the key gluconeogenic enzymes (phosphoenolpyruvate carboxykinase and glucose-6-phosphatase) in the liver tissues. Our findings revealed that berberine inhibited hepatic gluconeogenesis via the regulation of the LKB1-AMPK-TORC2

  13. INEEL Cultural Resource Management Program Annual Report - 2004

    International Nuclear Information System (INIS)

    Clayton F. Marler

    2005-01-01

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The Idaho National Engineering and Environmental Laboratory Site is located in southeastern Idaho, and is home to vast numbers and a wide variety of important cultural resources representing at least 13,000-year span of human occupation in the region. These resources are nonrenewable, bear valuable physical and intangible legacies, and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these resources with the management and ongoing operation of an active scientific laboratory, while also cleaning up the waste left by past programs and processes. The Department of Energy Idaho Operations Office has administrative responsibility for most of the Site, excluding lands and resources managed by the Naval Reactors Facility and (in 2004) Argonne National Laboratory-West. The Department of Energy is committed to a cultural resource program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative requirements. This annual report is an overview of Cultural Resource Management Program activities conducted during Fiscal Year 2004 and is intended to be both informative to external stakeholders and to serve as a planning tool for future cultural resource management work to be conducted on the Site

  14. INEEL Cultural Resource Management Program Annual Report - 2004

    Energy Technology Data Exchange (ETDEWEB)

    Clayton F. Marler

    2005-01-01

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The Idaho National Engineering and Environmental Laboratory Site is located in southeastern Idaho, and is home to vast numbers and a wide variety of important cultural resources representing at least 13,000-year span of human occupation in the region. These resources are nonrenewable, bear valuable physical and intangible legacies, and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these resources with the management and ongoing operation of an active scientific laboratory, while also cleaning up the waste left by past programs and processes. The Department of Energy Idaho Operations Office has administrative responsibility for most of the Site, excluding lands and resources managed by the Naval Reactors Facility and (in 2004) Argonne National Laboratory-West. The Department of Energy is committed to a cultural resource program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative requirements. This annual report is an overview of Cultural Resource Management Program activities conducted during Fiscal Year 2004 and is intended to be both informative to external stakeholders and to serve as a planning tool for future cultural resource management work to be conducted on the Site.

  15. CoalVal-A coal resource valuation program

    Science.gov (United States)

    Rohrbacher, Timothy J.; McIntosh, Gary E.

    2010-01-01

    CoalVal is a menu-driven Windows program that produces cost-of-mining analyses of mine-modeled coal resources. Geological modeling of the coal beds and some degree of mine planning, from basic prefeasibility to advanced, must already have been performed before this program can be used. United States Geological Survey mine planning is done from a very basic, prefeasibility standpoint, but the accuracy of CoalVal's output is a reflection of the accuracy of the data entered, both for mine costs and mine planning. The mining cost analysis is done by using mine cost models designed for the commonly employed, surface and underground mining methods utilized in the United States. CoalVal requires a Microsoft Windows? 98 or Windows? XP operating system and a minimum of 1 gigabyte of random access memory to perform operations. It will not operate on Microsoft Vista?, Windows? 7, or Macintosh? operating systems. The program will summarize the evaluation of an unlimited number of coal seams, haulage zones, tax entities, or other area delineations for a given coal property, coalfield, or basin. When the reader opens the CoalVal publication from the USGS website, options are provided to download the CoalVal publication manual and the CoalVal Program. The CoalVal report is divided into five specific areas relevant to the development and use of the CoalVal program: 1. Introduction to CoalVal Assumptions and Concepts. 2. Mine Model Assumption Details (appendix A). 3. CoalVal Project Tutorial (appendix B). 4. Program Description (appendix C). 5. Mine Model and Discounted Cash Flow Formulas (appendix D). The tutorial explains how to enter coal resource and quality data by mining method; program default values for production, operating, and cost variables; and ones own operating and cost variables into the program. Generated summary reports list the volume of resource in short tons available for mining, recoverable short tons by mining method; the seam or property being mined

  16. Measurement and analysis of P2P IPTV program resource.

    Science.gov (United States)

    Wang, Wenxian; Chen, Xingshu; Wang, Haizhou; Zhang, Qi; Wang, Cheng

    2014-01-01

    With the rapid development of P2P technology, P2P IPTV applications have received more and more attention. And program resource distribution is very important to P2P IPTV applications. In order to collect IPTV program resources, a distributed multi-protocol crawler is proposed. And the crawler has collected more than 13 million pieces of information of IPTV programs from 2009 to 2012. In addition, the distribution of IPTV programs is independent and incompact, resulting in chaos of program names, which obstructs searching and organizing programs. Thus, we focus on characteristic analysis of program resources, including the distributions of length of program names, the entropy of the character types, and hierarchy depth of programs. These analyses reveal the disorderly naming conventions of P2P IPTV programs. The analysis results can help to purify and extract useful information from chaotic names for better retrieval and accelerate automatic sorting of program and establishment of IPTV repository. In order to represent popularity of programs and to predict user behavior and popularity of hot programs over a period, we also put forward an analytical model of hot programs.

  17. Measurement and Analysis of P2P IPTV Program Resource

    Directory of Open Access Journals (Sweden)

    Wenxian Wang

    2014-01-01

    Full Text Available With the rapid development of P2P technology, P2P IPTV applications have received more and more attention. And program resource distribution is very important to P2P IPTV applications. In order to collect IPTV program resources, a distributed multi-protocol crawler is proposed. And the crawler has collected more than 13 million pieces of information of IPTV programs from 2009 to 2012. In addition, the distribution of IPTV programs is independent and incompact, resulting in chaos of program names, which obstructs searching and organizing programs. Thus, we focus on characteristic analysis of program resources, including the distributions of length of program names, the entropy of the character types, and hierarchy depth of programs. These analyses reveal the disorderly naming conventions of P2P IPTV programs. The analysis results can help to purify and extract useful information from chaotic names for better retrieval and accelerate automatic sorting of program and establishment of IPTV repository. In order to represent popularity of programs and to predict user behavior and popularity of hot programs over a period, we also put forward an analytical model of hot programs.

  18. A framework for evaluating and designing citizen science programs for natural resources monitoring.

    Science.gov (United States)

    Chase, Sarah K; Levine, Arielle

    2016-06-01

    We present a framework of resource characteristics critical to the design and assessment of citizen science programs that monitor natural resources. To develop the framework we reviewed 52 citizen science programs that monitored a wide range of resources and provided insights into what resource characteristics are most conducive to developing citizen science programs and how resource characteristics may constrain the use or growth of these programs. We focused on 4 types of resource characteristics: biophysical and geographical, management and monitoring, public awareness and knowledge, and social and cultural characteristics. We applied the framework to 2 programs, the Tucson (U.S.A.) Bird Count and the Maui (U.S.A.) Great Whale Count. We found that resource characteristics such as accessibility, diverse institutional involvement in resource management, and social or cultural importance of the resource affected program endurance and success. However, the relative influence of each characteristic was in turn affected by goals of the citizen science programs. Although the goals of public engagement and education sometimes complimented the goal of collecting reliable data, in many cases trade-offs must be made between these 2 goals. Program goals and priorities ultimately dictate the design of citizen science programs, but for a program to endure and successfully meet its goals, program managers must consider the diverse ways that the nature of the resource being monitored influences public participation in monitoring. © 2016 Society for Conservation Biology.

  19. Environmental Restoration Information Resource Management Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Environmental Restoration Information Resources Management (ER IRM) Program Plan defines program requirements, organizational structures and responsibilities, and work breakdown structure and to establish an approved baseline against which overall progress of the program as well as the effectiveness of its management will be measured. This plan will guide ER IRM Program execution and define the program`s essential elements. This plan will be routinely updated to incorporate key decisions and programmatic changes and will serve as the project baseline document. Environmental Restoration Waste Management Program intersite procedures and work instructions will be developed to facilitate the implementation of this plan.

  20. Developing Financial Resources for School Arts Programs.

    Science.gov (United States)

    Green, Alan C.; Ambler, Nancy Morison

    This document provides a sampling of financial resources for fine arts programs in the schools and lists methods for submitting proposals and dealing with sponsors of funds. Financial sources for arts programs include school districts, organizations and institutions, special events, direct mail, individuals, associations and clubs, businesses and…

  1. Environmental Restoration Information Resource Management Program Plan

    International Nuclear Information System (INIS)

    1994-09-01

    The Environmental Restoration Information Resources Management (ER IRM) Program Plan defines program requirements, organizational structures and responsibilities, and work breakdown structure and to establish an approved baseline against which overall progress of the program as well as the effectiveness of its management will be measured. This plan will guide ER IRM Program execution and define the program's essential elements. This plan will be routinely updated to incorporate key decisions and programmatic changes and will serve as the project baseline document. Environmental Restoration Waste Management Program intersite procedures and work instructions will be developed to facilitate the implementation of this plan

  2. Nuclear Human Resources Development Program using Educational Core Simulator

    International Nuclear Information System (INIS)

    Choi, Yu Sun; Hong, Soon Kwan

    2015-01-01

    KHNP-CRI(Korea Hydro and Nuclear Power Co.-Central Research Institute) has redesigned the existing Core Simulator(CoSi) used as a sort of training tools for reactor engineers in operating nuclear power plant to support Nuclear Human Resources Development (NHRD) Program focusing on the nuclear department of Dalat university in Vietnam. This program has been supported by MOTIE in Korea and cooperated with KNA(Korea Nuclear Association for International Cooperation) and HYU(Hanyang University) for enhancing the nuclear human resources of potential country in consideration with Korean Nuclear Power Plant as a next candidate energy sources. KHNP-CRI has provided Edu-CoSi to Dalat University in Vietnam in order to support Nuclear Human Resources Development Program in Vietnam. Job Qualification Certificates Program in KHNP is utilized to design a training course for Vietnamese faculty and student of Dalat University. Successfully, knowhow on lecturing the ZPPT performance, training and maintaining Edu-CoSi hardware are transferred by several training courses which KHNP-CRI provides

  3. Nuclear Human Resources Development Program using Educational Core Simulator

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yu Sun; Hong, Soon Kwan [KHNP-CRI, Daejeon (Korea, Republic of)

    2015-10-15

    KHNP-CRI(Korea Hydro and Nuclear Power Co.-Central Research Institute) has redesigned the existing Core Simulator(CoSi) used as a sort of training tools for reactor engineers in operating nuclear power plant to support Nuclear Human Resources Development (NHRD) Program focusing on the nuclear department of Dalat university in Vietnam. This program has been supported by MOTIE in Korea and cooperated with KNA(Korea Nuclear Association for International Cooperation) and HYU(Hanyang University) for enhancing the nuclear human resources of potential country in consideration with Korean Nuclear Power Plant as a next candidate energy sources. KHNP-CRI has provided Edu-CoSi to Dalat University in Vietnam in order to support Nuclear Human Resources Development Program in Vietnam. Job Qualification Certificates Program in KHNP is utilized to design a training course for Vietnamese faculty and student of Dalat University. Successfully, knowhow on lecturing the ZPPT performance, training and maintaining Edu-CoSi hardware are transferred by several training courses which KHNP-CRI provides.

  4. Development of synthetic analysis program concerning on the safety of energy resources

    Energy Technology Data Exchange (ETDEWEB)

    Chang, S. H.; Choi, S. S.; Cheong, Y. H.; Ahn, S. H.; Chang, W. J. [Atomic Creative Technology, Daejeon (Korea, Republic of)

    2007-03-15

    Methodology development of synthetic analysis of energy resources: build system methodology of synthetic analysis of energy resources. Development of web-based enquete program, develop web-based enquete program to support synthetic analysis of energy resources. Aggregation Software development, develop AHP algorithm and aggregation software for the synthetic analysis of energy resources.

  5. Education Program on Fossil Resources Including Coal

    Science.gov (United States)

    Usami, Masahiro

    Fossil fuels including coal play a key role as crucial energies in contributing to economic development in Asia. On the other hand, its limited quantity and the environmental problems causing from its usage have become a serious global issue and a countermeasure to solve such problems is very much demanded. Along with the pursuit of sustainable development, environmentally-friendly use of highly efficient fossil resources should be therefore, accompanied. Kyushu-university‧s sophisticated research through long years of accumulated experience on the fossil resources and environmental sectors together with the advanced large-scale commercial and empirical equipments will enable us to foster cooperative research and provide internship program for the future researchers. Then, this program is executed as a consignment business from the Ministry of Economy, Trade and Industry from 2007 fiscal year to 2009 fiscal year. The lecture that uses the textbooks developed by this program is scheduled to be started a course in fiscal year 2010.

  6. Resource values in analyzing fire management programs for economic efficiency

    Science.gov (United States)

    Irene A. Althaus; Thomas J. Mills

    1982-01-01

    In analyzing fire management programs for their economic efficiency, it is necessary to assign monetary values to the changes in resource outputs caused by, fire. The derivation of resource values is complicated by imperfect or nonexistent commercial market structures. The valuation concept recommended for fire program analyses is willingness-to-pay because it permits...

  7. FASP, an analytic resource appraisal program for petroleum play analysis

    Science.gov (United States)

    Crovelli, R.A.; Balay, R.H.

    1986-01-01

    An analytic probabilistic methodology for resource appraisal of undiscovered oil and gas resources in play analysis is presented in a FORTRAN program termed FASP. This play-analysis methodology is a geostochastic system for petroleum resource appraisal in explored as well as frontier areas. An established geologic model considers both the uncertainty of the presence of the assessed hydrocarbon and its amount if present. The program FASP produces resource estimates of crude oil, nonassociated gas, dissolved gas, and gas for a geologic play in terms of probability distributions. The analytic method is based upon conditional probability theory and many laws of expectation and variance. ?? 1986.

  8. A Compromise Programming Model for Highway Maintenance Resources Allocation Problem

    Directory of Open Access Journals (Sweden)

    Hui Xiong

    2012-01-01

    Full Text Available This paper formulates a bilevel compromise programming model for allocating resources between pavement and bridge deck maintenances. The first level of the model aims to solve the resource allocation problems for pavement management and bridge deck maintenance, without considering resource sharing between them. At the second level, the model uses the results from the first step as an input and generates the final solution to the resource-sharing problem. To solve the model, the paper applies genetic algorithms to search for the optimal solution. We use a combination of two digits to represent different maintenance types. Results of numerical examples show that the conditions of both pavements and bridge decks are improved significantly by applying compromise programming, rather than conventional methods. Resources are also utilized more efficiently when the proposed method is applied.

  9. 34 CFR 669.1 - What is the Language Resource Centers Program?

    Science.gov (United States)

    2010-07-01

    ... improving the nation's capacity for teaching and learning foreign languages effectively. (Authority: 20 U.S... 34 Education 3 2010-07-01 2010-07-01 false What is the Language Resource Centers Program? 669.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION LANGUAGE RESOURCE CENTERS PROGRAM General § 669.1 What is the...

  10. Yucca Mountain Biological resources monitoring program

    International Nuclear Information System (INIS)

    1991-01-01

    The US Department of Energy (US DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a possible site for a geological repository for high-level radioactive waste. To ensure site characterization activities do not adversely affect the Yucca Mountain area, an environmental program, the Yucca Mountain Biological Resources Monitoring Program, has been implemented monitor and mitigate environmental impacts and to ensure activities comply with applicable environmental laws. Potential impacts to vegetation, small mammals, and the desert tortoise (an indigenous threatened species) are addressed, as are habitat reclamation, radiological monitoring, and compilation of baseline data. This report describes the program in Fiscal Years 1989 and 1990. 12 refs., 4 figs., 17 tabs

  11. US Department of Energy Integrated Resource Planning Program: Accomplishments and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    White, D.L. [Oak Ridge National Lab., TN (United States); Mihlmester, P.E. [Aspen Systems Corp., Oak Ridge, TN (United States)

    1993-12-17

    The US Department of Energy Integrated Resource Planning Program supports many activities and projects that enhance the process by which utilities assess demand and supply options and, subsequently, evaluate and select resources. The US Department of Energy program coordinates integrated resource planning in risk and regulatory analysis; utility and regional planning; evaluation and verification; information transfer/technological assistance; and demand-side management. Professional staff from the National Renewable Energy Laboratory, Oak Ridge National Laboratory, Lawrence Berkeley Laboratory, and Pacific Northwest Laboratories collaborate with peers and stakeholders, in particular, the National Association of Regulatory Utility Commissioners, and conduct research and activities for the US Department of Energy. Twelve integrated resource planning activities and projects are summarized in this report. The summaries reflect the diversity of planning and research activities supported by the Department. The summaries also reflect the high levels of collaboration and teaming that are required by the Program and practiced by the researchers. It is concluded that the Program is achieving its objectives by encouraging innovation and improving planning and decision making. Furthermore, as the Department continues to implement planned improvements in the Program, the Department is effectively positioned to attain its ambitious goals.

  12. 25 CFR 36.102 - What student resources must be provided by a homeliving program?

    Science.gov (United States)

    2010-04-01

    ... homeliving program? The following minimum resources must be available at all homeliving programs: (a) Library resources such as access to books and resource materials, including school libraries and public libraries...

  13. Time Aquatic Resources Modeling and Analysis Program (STARMAP)

    Data.gov (United States)

    Federal Laboratory Consortium — Colorado State University has received funding from the U.S. Environmental Protection Agency (EPA) for its Space-Time Aquatic Resources Modeling and Analysis Program...

  14. Water-resources programs and hydrologic-information needs, Marion County, Indiana, 1987

    Science.gov (United States)

    Duwelius, R.F.

    1990-01-01

    Water resources are abundant in Marion County, Indiana, and have been developed for public and industrial supply, energy generation, irrigation, and recreation. The largest water withdrawals are from surface water, and the two largest water uses are public supply and cooling water for electrical-generating plants. Water-resources programs in the county are carried out by Federal, State and local agencies to address issues of surface and groundwater availability and quality. The programs of each agency are related to the functions and goals of the agency. Although each agency has specific information needs to fulfill its functions, sometimes these needs overlap, and there are times when the same hydrologic information benefits all. Overlapping information needs and activities create opportunities for interagency coordination and cooperation. Such cooperation could lead to a savings of dollars spent on water-resources programs and could assure an improved understanding of the water resources of the county. Representatives from four agencies-- the Indiana Department of Environmental Management, the Indiana Department of Natural Resources, the Indianapolis Department of Public Works, and the U.S. Geological Survey--met four times in 1987 to describe their own water-resources programs, to identify hydrologic-information needs, and to contact other agencies with related programs. This report presents the interagency findings and is intended to further communication among water resource agencies by identifying current programs and common needs for hydrologic information. Hydrologic information needs identified by the agency representatives include more precise methods for determining the volume of water withdrawals and for determining the volume of industrial and municipal discharges to surface water. Maps of flood-prone areas need to be updated as more of the county is developed. Improved aquifer maps of the inter-till aquifers are needed, and additional observation

  15. U.S. Immunization program adult immunization activities and resources

    Science.gov (United States)

    Woods, LaDora O.; Bridges, Carolyn B.; Graitcer, Samuel B.; Lamont, Brock

    2016-01-01

    ABSTRACT Adults are recommended to receive vaccines based on their age, medical conditions, prior vaccinations, occupation and lifestyle. However, adult immunization coverage is low in the United States and lags substantially below Healthy People 2020 goals. To assess activities and resources designated for adult immunization programs by state and local health department immunization programs in the United States, we analyzed 2012 and 2013 data from the Centers for Disease Control and Prevention's (CDC) Program Annual Reports and Progress Assessments (PAPA) survey of CDC-funded immunization programs. Fifty-six of 64 funded US immunization programs' responses were included in the analysis. Eighty-two percent of (n = 46) programs reported having a designated adult immunization coordinator in 2012 and 73% (n = 41) in 2013. Of the 46 coordinators reported in 2012, 30% (n = 14) spent more than 50% of their time on adult immunization activities, and only 24% (n = 10) of the 41 adult coordinators in 2013 spent more than 50% of their time on adult immunization activities. In 2012, 23% (n = 13) of the 56 programs had a separate immunization coalition for adults and 68% (n = 38) included adult issues in their overall immunization program coalition. In 2013, 25% (n = 14) had a separate adult immunization coalition while 57% (n = 32) incorporated adult immunizations into their overall immunization program coalition. The results indicate substantial variation across the US in public health infrastructure to support adult immunizations. Continued assessment of adult immunization resources and activities will be important in improving adult immunization coverage levels though program support. With many programs having limited resources dedicated to improving adult immunization rates in the in US, efforts by the health departments to collaborate with providers and other partners in their jurisdictions to increase awareness, increase the use of proven strategies to improve

  16. IAEA Nuclear Security Human Resource Development Program

    International Nuclear Information System (INIS)

    Braunegger-Guelich, A.

    2009-01-01

    The IAEA is at the forefront of international efforts to strengthen the world's nuclear security framework. The current Nuclear Security Plan for 2006-2009 was approved by the IAEA Board of Governors in September 2005. This Plan has three main points of focus: needs assessment, prevention, detection and response. Its overall objective is to achieve improved worldwide security of nuclear and other radioactive material in use, storage and transport, and of their associated facilities. This will be achieved, in particular, through the provision of guidelines and recommendations, human resource development, nuclear security advisory services and assistance for the implementation of the framework in States, upon request. The presentation provides an overview of the IAEA nuclear security human resource development program that is divided into two parts: training and education. Whereas the training program focuses on filling gaps between the actual performance of personnel working in the area of nuclear security and the required competencies and skills needed to meet the international requirements and recommendations described in UN and IAEA documents relating to nuclear security, the Educational Program in Nuclear Security aims at developing nuclear security experts and specialists, at fostering a nuclear security culture and at establishing in this way sustainable knowledge in this field within a State. The presentation also elaborates on the nuclear security computer based learning component and provides insights into the use of human resource development as a tool in achieving the IAEA's long term goal of improving sustainable nuclear security in States. (author)

  17. USGS research on energy resources, 1986; program and abstracts

    Science.gov (United States)

    Carter, Lorna M.H.

    1986-01-01

    The extended abstracts in this volume are summaries of the papers presented orally and as posters in the second V. E. McKelvey Forum on Mineral and Energy Resources, entitled "USGS Research on Energy Resources-1986." The Forum has been established to improve communication between the USGS and the earth science community by presenting the results of current USGS research on nonrenewable resources in a timely fashion and by providing an opportunity for individuals from other organizations to meet informally with USGS scientists and managers. It is our hope that the McKelvey Forum will help to make USGS programs more responsive to the needs of the earth science community, particularly the mining and petroleum industries, and Win foster closer cooperation between organizations and individuals. The Forum was named after former Director Vincent E. McKelvey in recognition of his lifelong contributions to research, development, and administration in mineral and energy resources, as a scientist, as Chief Geologist, and as Director of the U.S. Geological Survey. The Forum will be an annual event, and its subject matter will alternate between mineral and energy resources. We expect that the format will change somewhat from year to year as various approaches are tried, but its primary purpose will remain the same: to encourage direct communication between USGS scientists and the representatives of other earth-science related organizations. Energy programs of the USGS include oil and gas, coal, geothermal, uranium-thorium, and oil shale; work in these programs spans the national domain, including surveys of the offshore Exclusive Economic Zone. The topics selected for presentation at this McKelvey Forum represent an overview of the scientific breadth of USGS research on energy resources. They include aspects of petroleum occurrence in Eastern United States rift basins, the origin of magnetic anomalies over oil fields, accreted terranes and energy-resource implications, coal

  18. Final Environmental Impact Statement Resource Programs

    International Nuclear Information System (INIS)

    1993-02-01

    BPA's preferred alternative is the Emphasize Conservation Alternative. System and environmental costs are low. Environmental impacts from conservation are minimal. This alternative is cost-effective and environmentally responsible; only the High Conservation Alternative has lower costs and fewer environmental impacts. However, there is some concern about the cost-effectiveness, reliability, and commercial availability of the high conservation resources. If the supply of the additional conservation potential was confirmed and it became cost-effective, the High Conservation Alternative would be preferred. The Draft Resource Programs EIS was released for public review during the summer of 1992. Comments received by letter or in the public hearing held June 16, 1992, were used to revise and update data and analyses of the EIS (public comments and BPA's responses are contained in Volume III of the Final EIS). In addition, a number of revisions were made in the Chapter 3 material describing each resource type, and in Chapter 4 and the Summary, to assure consistency with the modeling and analysis in Chapter 5. Additional information about the capacity aspects of each resource type and alternative has been added, and the material on conservation and its impacts has been reorganized

  19. NANA Wind Resource Assessment Program Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Jay Hermanson

    2010-09-23

    NANA Regional Corporation (NRC) of northwest Alaska is located in an area with abundant wind energy resources. In 2007, NRC was awarded grant DE-FG36-07GO17076 by the US Department of Energy's Tribal Energy Program for funding a Wind Resource Assessment Project (WRAP) for the NANA region. The NANA region, including Kotzebue Electric Association (KEA) and Alaska Village Electric Cooperative (AVEC) have been national leaders at developing, designing, building, and operating wind-diesel hybrid systems in Kotzebue (starting in 1996) and Selawik (2002). Promising sites for the development of new wind energy projects in the region have been identified by the WRAP, including Buckland, Deering, and the Kivalina/Red Dog Mine Port Area. Ambler, Shungnak, Kobuk, Kiana, Noorvik & Noatak were determined to have poor wind resources at sites in or very near each community. However, all five of these communities may have better wind resources atop hills or at sites with slightly higher elevations several miles away.

  20. Resource-agnostic programming for many-core microgrids

    NARCIS (Netherlands)

    Bernard, T.A.M.; Grelck, C.; Hicks, M.A.; Jesshope, C.R.; Poss, R.; Forsell, M.; Träff, J.L.

    2010-01-01

    Many-core architectures are a commercial reality, but programming them efficiently is still a challenge, especially if the mix is heterogeneous. Here granularity must be addressed, i.e. when to make use of concurrency resources and when not to. We have designed a data-driven, fine-grained concurrent

  1. Federal Smart Cities and Communities Programs Resource Guide

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — The Federal Smart Cities and Communities Task Force created the " Federal Smart Cities and Communities Programs Resource Guide " to facilitate collaboration and...

  2. The Impacts of the Great Recession on State Natural Resource Extension Programs

    Science.gov (United States)

    Serenari, Christopher; Peterson, M. Nils; Bardon, Robert E.; Brown, Robert D.

    2013-01-01

    The Great Recession contributed to major budget cuts for natural resource Extension programs in the United States. Despite the potentially large cuts, their impacts and how Extension has adapted their programs have not been evaluated. We begin addressing these needs with surveys of Association of Natural Resource Extension Professionals members…

  3. NASA'S Water Resources Element Within the Applied Sciences Program

    Science.gov (United States)

    Toll, David; Doorn, Bradley; Engman, Edwin

    2010-01-01

    The NASA Applied Sciences Program works within NASA Earth sciences to leverage investment of satellite and information systems to increase the benefits to society through the widest practical use of NASA research results. Such observations provide a huge volume of valuable data in both near-real-time and extended back nearly 50 years about the Earth's land surface conditions such as land cover type, vegetation type and health, precipitation, snow, soil moisture, and water levels and radiation. Observations of this type combined with models and analysis enable satellite-based assessment of numerous water resources management activities. The primary goal of the Earth Science Applied Science Program is to improve future and current operational systems by infusing them with scientific knowledge of the Earth system gained through space-based observation, model results, and development and deployment of enabling technologies, systems, and capabilities. Water resources is one of eight elements in the Applied Sciences Program and it addresses concerns and decision making related to water quantity and water quality. With increasing population pressure and water usage coupled with climate variability and change, water issues are being reported by numerous groups as the most critical environmental problems facing us in the 21st century. Competitive uses and the prevalence of river basins and aquifers that extend across boundaries engender political tensions between communities, stakeholders and countries. Mitigating these conflicts and meeting water demands requires using existing resources more efficiently. The potential crises and conflicts arise when water is competed among multiple uses. For example, urban areas, environmental and recreational uses, agriculture, and energy production compete for scarce resources, not only in the Western U.S. but throughout much of the U.S. but also in many parts of the world. In addition to water availability issues, water quality related

  4. Resources for Developing Acquaintance Rape Prevention Programs for Men.

    Science.gov (United States)

    Earle, James P.; Nies, Charles T.

    1994-01-01

    Provides an annotated bibliography of videos and printed materials that may be used as educational tools in rape prevention programs. Focuses on sources that are aimed directly at men. Also outlines the use of consultants or lecturers as one of many resources in the construction and implementation of rape prevention programs. (KW)

  5. Sustainable Agriculture and Natural Resource Management Collaborative Research Support Program(SANREM CRSP)

    OpenAIRE

    Moore, Keith M.

    2007-01-01

    This presentation describes the history and current program of the Sustainable Agriculture and Natural Resource Management Collaborative Research Support Program (SANREM CRSP). SANREM Objectives include increasing stakeholder income generation capacity, empowering stakeholders, particularly women, enhancing decentralized resource management, strengthening local institutions, improving market access for smallholders and communities, and promoting sustainable and environmentally sound developme...

  6. Improving Program Design and Assessment with Broadening Participation Resources

    Science.gov (United States)

    Siegfried, D.; Johnson, A.; Thomas, S. H.; Fauver, A.; Detrick, L.

    2012-12-01

    Many theoretical and research-based approaches suggest how to best use mentoring to enhance an undergraduate research program. The Institute for Broadening Participation's Pathways to Engineering and Pathways to Ocean Sciences projects synthesized a set of mentoring studies, theoretical sources, and other texts pertinent to undergraduate research program design into a suite of practical tools that includes an online mentoring manual, an online reference library of mentoring and diversity literature, and practical guides such as Using Social Media to Build Diversity in Your REU. The overall goal is to provide easy-to-access resources that can assist faculty and program directors in implementing or honing the mentoring elements in their research programs for undergraduates. IBP's Online Mentoring Manual addresses common themes, such as modeling, student self-efficacy, career development, retention and evaluation. The Online Diversity Reference Library provides a comprehensive, annotated selection of key policy documents, research studies, intervention studies, and other texts on broadening participation in science, technology, engineering and mathematics. IBP's suite of tools provides the theoretical underpinnings and research findings that can help leaders in education integrate site-appropriate mentoring elements into their educational programs. Program directors and faculty from a variety of program types and disciplines have benefitted from using the Manual and other resources. IBP continues the work of translating and synthesizing theory to practice and welcomes your participation and partnership in that effort.

  7. State Electricity Regulatory Policy and Distributed Resources: Distributed Resource Distribution Credit Pilot Programs--Revealing the Value to Consumers and Vendors

    Energy Technology Data Exchange (ETDEWEB)

    Moskovitz, D.; Harrington, C.; Shirley, W.; Cowart, R.; Sedano, R.; Weston, F.

    2002-10-01

    Designing and implementing credit-based pilot programs for distributed resources distribution is a low-cost, low-risk opportunity to find out how these resources can help defer or avoid costly electric power system (utility grid) distribution upgrades. This report describes implementation options for deaveraged distribution credits and distributed resource development zones. Developing workable programs implementing these policies can dramatically increase the deployment of distributed resources in ways that benefit distributed resource vendors, users, and distribution utilities. This report is one in the State Electricity Regulatory Policy and Distributed Resources series developed under contract to NREL (see Annual Technical Status Report of the Regulatory Assistance Project: September 2000-September 2001, NREL/SR-560-32733). Other titles in this series are: (1) Accommodating Distributed Resources in Wholesale Markets, NREL/SR-560-32497; (2) Distributed Resources and Electric System Re liability, NREL/SR-560-32498; (3) Distribution System Cost Methodologies for Distributed Generation, NREL/SR-560-32500; (4) Distribution System Cost Methodologies for Distributed Generation Appendices, NREL/SR-560-32501.

  8. The U.S.Geological Survey Energy Resources Program

    Science.gov (United States)

    ,

    2010-01-01

    Energy resources are an essential component of modern society. Adequate, reliable, and affordable energy supplies obtained using environmentally sustainable practices underpin economic prosperity, environmental quality and human health, and political stability. National and global demands for all forms of energy are forecast to increase significantly over the next several decades. Throughout its history, our Nation has faced important, often controversial, decisions regarding the competing uses of public lands, the supply of energy to sustain development and enable growth, and environmental stewardship. The U.S. Geological Survey (USGS) Energy Resources Program (ERP) provides information to address these challenges by supporting scientific investigations of energy resources, such as research on the geology, geochemistry, and geophysics of oil, gas, coal, heavy oil and natural bitumen, oil shale, uranium, and geothermal resources, emerging resources such as gas hydrates, and research on the effects associated with energy resource occurrence, production, and (or) utilization. The results from these investigations provide impartial, robust scientific information about energy resources and support the U.S. Department of the Interior's (DOI's) mission of protecting and responsibly managing the Nation's natural resources. Primary consumers of ERP information and products include the DOI land- and resource-management Bureaus; other Federal, State, and local agencies; the U.S. Congress and the Administration; nongovernmental organizations; the energy industry; academia; international organizations; and the general public.

  9. [Resource allocation analysis for international cooperation program for HIV/AIDS prevention and control].

    Science.gov (United States)

    Li, Hui; Xue, Hui; Liu, Hui; Guo, Hao-yan; Zhang, Hua; Sun, Jiang-ping

    2008-12-01

    To provide evidence for resource allocation and cooperation between domestic and international HIV/AIDS programs in China by analyzing the needs and current levels of resource input in provinces. National and provincial international cooperation program investment and allocation data from 2000 to 2006 were collected. Several factors in each province were analyzed through multiple regression analysis in order to determine whether they had a statistical correlation to the distribution of international HIV/AIDS program resources in China, including: the Gross Domestic Product (GDP), the number of accumulated people living with HIV/AIDS, and the number of accumulated people living with AIDS. Then the Z values were calculated at each provincial level and compared with related international investment. The resource allocation in different program areas were compared with the level of resource input by international and central government HIV/AIDS prevention and control programs through Chi-square test. The international cooperation program investment at local level from 2000 to 2006 were 4893, 24 669, 50 567, 52 950, 112 143, 363 396 and 247 045 thousand RMB respectively, and at national level were 3007, 19 726, 29 035, 37 530, 77 500, 105 786 and 77 035 thousand RMB respectively. There was a statistical correlation between international HIV/AIDS program resource input and the accumulated number of people living with AIDS (R is 0.56 and 0.69 accordingly, and P international resource input and the GDP of each province. International HIV/AIDS cooperation programs did not invest in each province according to its practical needs (R = 0.066, P = 0.725). The international cooperation program investments and needs in different province could not meet completely. The ranks of Z value in Guangdong, Shandong and Jiangsu were 3, 5 and 6, but the ranks of international cooperation program in those provinces were 18, 13 and 28 respectively. The investment proportion for national

  10. ``Dark Skies are a Universal Resource'' Programs Planned for the International Year of Astronomy

    Science.gov (United States)

    Walker, C. E.; Berglund, K.; Bueter, C.; Crelin, B.; Duriscoe, D.; Moore, C.; Gauthier, A.; Gay, P. L.; Foster, T.; Heatherly, S. A.; Maddalena, R.; Mann, T.; Patten, K.; Pompea, S. M.; Sparks, R.; Schaaf, F.; Simmons, M.; Smith, C.; Smith, M.; Tafreshi, B.

    2008-11-01

    In an effort to help more people appreciate the ongoing loss of a dark night sky for much of the world's population and to raise public knowledge about diverse impacts of excess artificial lighting on local environments, the International Year of Astronomy's Dark Skies Working Group has established six ``Dark Skies'' programs and six ``Dark Skies'' resources. The Dark Skies programs include GLOBE at Night (with Earth Hour), Astronomy Nights in the [National] Parks, Dark Skies Discovery Sites, Quiet Skies, Good Neighbor Lighting, and a digital photography contest. Resources include the light education toolkit, the ``Let There Be Night'' DVD and planetarium program, the 6-minute video, online interactions like Second Life, podcasts, and traveling exhibits. The programs and resources are summarized here, as they were in a poster for the June 2008 ASP/AAS conference. For more information on these programs and resources, visit http://astronomy2009.us/darkskies/.

  11. Energy resources technical training and development programs for American Indians

    Energy Technology Data Exchange (ETDEWEB)

    Cameron, R E; White, W S

    1978-08-01

    Because of the energy resources located on Native American owned lands, it is pertinent that the tribes on these reservations receive information, training, and technical assistance concerning energy and the environment and the decisions that must be made about energy-resource development. In the past, attempts to enlist Indians in technical-assistance programs met with little success because teaching methods seldom incorporated program planning by both tribal leaders and the technical training staff. Several technical-assistance programs given on reservations in the central and western parts of the country were conducted by Argonne National Lab.--programs that stressed practical, on-the-job experience through lecture, laboratory, and field studies. Each program was designed by ANL and tribal leaders to fit the needs and concerns of a particular tribe for its environment. The individual programs met with an impressive degree of success; they also prompted several Indians to pursue this type of education further at ANL and local Indian community colleges and to obtain funds for energy projects. Despite the positive feedback, several difficulties were encountered. Among them are the necessity to continually modify the programs to fit diverse tribal needs, to diminish politically motivated interference, and to increase portions of the funding to involve more Native Americans.

  12. 34 CFR 656.1 - What is the National Resource Centers Program?

    Science.gov (United States)

    2010-07-01

    ... STUDIES OR FOREIGN LANGUAGE AND INTERNATIONAL STUDIES General § 656.1 What is the National Resource... Foreign Language and International Studies (National Resource Centers Program), the Secretary awards... international studies and the international and foreign language aspects of professional and other fields of...

  13. Learning on human resources management in the radiology residency program

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Aparecido Ferreira de; Lederman, Henrique Manoel; Batista, Nildo Alves, E-mail: aparecidoliveira@ig.com.br [Universidade Federal de Sao Paulo (EPM/UNIFESP), Sao Paulo, SP (Brazil). Escola Paulista de Medicina

    2014-03-15

    Objective: to investigate the process of learning on human resource management in the radiology residency program at Escola Paulista de Medicina - Universidade Federal de Sao Paulo, aiming at improving radiologists' education. Materials and methods: exploratory study with a quantitative and qualitative approach developed with the faculty staff, preceptors and residents of the program, utilizing a Likert questionnaire (46), taped interviews (18), and categorization based on thematic analysis. Results: According to 71% of the participants, residents have clarity about their role in the development of their activities, and 48% said that residents have no opportunity to learn how to manage their work in a multidisciplinary team. Conclusion: Isolation at medical records room, little interactivity between sectors with diversified and fixed activities, absence of a previous culture and lack of a training program on human resources management may interfere in the development of skills for the residents' practice. There is a need to review objectives of the medical residency in the field of radiology, incorporating, whenever possible, the commitment to the training of skills related to human resources management thus widening the scope of abilities of the future radiologists. (author)

  14. Learning on human resources management in the radiology residency program

    International Nuclear Information System (INIS)

    Oliveira, Aparecido Ferreira de; Lederman, Henrique Manoel; Batista, Nildo Alves

    2014-01-01

    Objective: to investigate the process of learning on human resource management in the radiology residency program at Escola Paulista de Medicina - Universidade Federal de Sao Paulo, aiming at improving radiologists' education. Materials and methods: exploratory study with a quantitative and qualitative approach developed with the faculty staff, preceptors and residents of the program, utilizing a Likert questionnaire (46), taped interviews (18), and categorization based on thematic analysis. Results: According to 71% of the participants, residents have clarity about their role in the development of their activities, and 48% said that residents have no opportunity to learn how to manage their work in a multidisciplinary team. Conclusion: Isolation at medical records room, little interactivity between sectors with diversified and fixed activities, absence of a previous culture and lack of a training program on human resources management may interfere in the development of skills for the residents' practice. There is a need to review objectives of the medical residency in the field of radiology, incorporating, whenever possible, the commitment to the training of skills related to human resources management thus widening the scope of abilities of the future radiologists. (author)

  15. The 1980-1982 Geothermal Resource Assessment Program in Washington

    Energy Technology Data Exchange (ETDEWEB)

    Korosec, Michael A.; Phillips, William M.; Schuster, J.Eric

    1983-08-01

    Since 1978, the Division of Geology and Earth Resources of the Washington Department of Natural Resources has participated in the U.S. Department of Energy's (USDOE) State-Coupled Geothermal Resource Program. Federal and state funds have been used to investigate and evaluate the potential for geothermal resources, on both a reconnaissance and area-specific level. Preliminary results and progress reports for the period up through mid-1980 have already been released as a Division Open File Report (Korosec, Schuster, and others, 1981). Preliminary results and progress summaries of work carried out from mid-1980 through the end of 1982 are presented in this report. Only one other summary report dealing with geothermal resource investigations in the state has been published. An Information Circular released by the Division (Schuster and others, 1978) compiled the geology, geochemistry, and heat flow drilling results from a project in the Indian Heaven area in the south Cascades. The previous progress report for the geothermal program (Korosec, Schuster, and others, 1981) included information on temperature gradients measured throughout the state, heat flow drilling in the southern Cascades, gravity surveys for the southern Cascades, thermal and mineral spring investigations, geologic mapping for the White Pass-Tumac Mountain area, and area specific studies for the Camas area of Clark County and Mount St. Helens. This work, along with some additional studies, led to the compilation of the Geothermal Resources of Washington map (Korosec, Kaler, and others, 1981). The map is principally a nontechnical presentation based on all available geothermal information, presented as data points, tables, and text on a map with a scale of 1:500,000.

  16. Economic Education Programs and Resources Directory. Second Edition.

    Science.gov (United States)

    National Association of Manufacturers, Washington, DC.

    This directory provides a selective listing of information about economic education programs and resource activities of 299 corporations, organizations, universities, and colleges in the United States. This second edition of the directory is intended to stimulate interaction between business firms and schools and to help educators, members of the…

  17. Citizen science and natural resource governance: program design for vernal pool policy innovation

    Directory of Open Access Journals (Sweden)

    Bridie McGreavy

    2016-06-01

    Full Text Available Effective natural resource policy depends on knowing what is needed to sustain a resource and building the capacity to identify, develop, and implement flexible policies. This retrospective case study applies resilience concepts to a 16-year citizen science program and vernal pool regulatory development process in Maine, USA. We describe how citizen science improved adaptive capacities for innovative and effective policies to regulate vernal pools. We identified two core program elements that allowed people to act within narrow windows of opportunity for policy transformation, including (1 the simultaneous generation of useful, credible scientific knowledge and construction of networks among diverse institutions, and (2 the formation of diverse leadership that promoted individual and collective abilities to identify problems and propose policy solutions. If citizen science program leaders want to promote social-ecological systems resilience and natural resource policies as outcomes, we recommend they create a system for internal project evaluation, publish scientific studies using citizen science data, pursue resources for program sustainability, and plan for leadership diversity and informal networks to foster adaptive governance.

  18. European Community's program in marine resources development

    International Nuclear Information System (INIS)

    Lenoble, J.P.; Jarmache, E.

    1995-01-01

    The European Community launched already several research program in the different fields of social and industrial activities. The Fourth Framework Programme is divided into 4 main activities comporting a total of 18 programs. These programs are dealing with general topics as information and communication, industrial technologies, environment, life sciences and technologies, energy, transport and socioeconomic research. One line is devoted to marine sciences and technology, but offshore activities could also be included in the other topics as offshore oil and gas in energy, ship building and harbor in transport, aquaculture and fisheries in life sciences and technology, etc. In order to maintain a coherent approach toward offshore activities, the European maritime industries met intensively front 1991 to 1994 and recommended a series of proposal for Research and Development of marine resources. The methodology and content of these proposals is exposed

  19. US DOE Radiological Assistance Program: personnel, equipment and resources

    International Nuclear Information System (INIS)

    Hull, A.P.; Kuehner, A.V.; Phillips, L.F.

    1982-01-01

    The Radiological Assistance Program (RAP) of the US Department of Energy (DOE) is intended to provide emergency advice and assistance in the event of radiological incidents. Each of DOE's eight Regional Coordinating Offices in the US provide a 24-hour reporting and response capability. Specifically, the Brookhaven Area Office (BHO) is responsible for DOE's Region I, which includes the 11 northeastern states of the US. Although an inventory of dedicated equipment is assigned to BHO-RAP, it draws upon the resources of Brookhaven National Laboratory (BNL) for trained personnel in health physics and for other specialized personnel in both the day to day operation of the program and in the on-the-scene response to an incident. The organization of the BHO-RAP program and its response procedures are described in detail. An inventory and brief description of the contents of a variety of emergency equipment kits and of additional state-of-the-art instruments is included. The BHO-RAP guidelines and requirements for field operations are also indicated, as are other DOE resources upon which it can draw

  20. Connecting Youth to High-Resource Adults: Lessons from Effective Youth Programs

    Science.gov (United States)

    Sullivan, Patrick J.; Larson, Reed W.

    2010-01-01

    Adolescents benefit from contact with high-resource community adults, but intergenerational obstacles make these interactions difficult, fragile, and rare. This qualitative research investigated the success of seven, primarily urban, leadership, and arts programs that attempted to facilitate these interactions within their programming. Program…

  1. 1976 Inter-university symposium on renewable resource assessment and programming: executive summary

    Science.gov (United States)

    Billy G. Pemberton

    1977-01-01

    The Forest and Rangeland Renewable Resources Planning Act of 1974 directs the Secretary of Agriculture to prepare an assessment of the nation's renewable resources and a program that will assure an adequate future supply of these resources. Responsibility for this work is assigned to the Forest Service. An inter-university symposium was held in 1976 to evaluate...

  2. Assessment of the human resources infrastructure for nuclear energy program in Macedonia

    International Nuclear Information System (INIS)

    Chaushevski, A.; Spasevska, H.; Nikolova-Poceva, S.; Popov, P.

    2015-01-01

    Macedonia is a country with no nuclear power and research reactors. The nuclear application is currently only in the medical industry, agriculture and food industry, accompanied by radiation measuring and protection activities in these sectors. On the other side the energy needs have been increasing in the last ten years, which resulted in electrical energy import of about 20–30% (around 3000 GWh). Nuclear power is one of the options for satisfying energy needs in the next 50 years. One of the crucial problems in nuclear energy implementation are human resources needs and educational infrastructure development in this field. No matter what will be the future energy scenario in the Republic of Macedonia, the nuclear educational program is the first step to have HR in the field of nuclear energy. This paper presents the proposed direction for having HR in nuclear energy program in a small country such as the Republic of Macedonia. Taking into account the existing national education program related to nuclear topics and in particular to nuclear power, and following the guidance and recommendations from the international nuclear educational programs at the IAEA, EHRO and others, the planning of the educational nuclear programs and human resources development in the Republic of Macedonia has been carried out. This includes the enhancing the capabilities of the national regulatory body in the Republic of Macedonia. (authors) Keywords: NEP (Nuclear Energy Program), HR (Human Resources), NEPIO (Nuclear Energy Program Implementation Organization), NRB (Nuclear Regulatory Body), NPP

  3. Parkinson’s Disease Biomarkers Program Data Management Resource (PDBP DMR)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The NINDS Parkinson’s Disease (PD) Biomarkers Program Data Management Resource enables web-based data entry for clinical studies supporting PD biomarker development,...

  4. Using information management to implement a clinical resource management program.

    Science.gov (United States)

    Rosenstein, A H

    1997-12-01

    This article provides a consultant's account of a 250-bed community hospital's experience in implementing the Clinical Resource Management (CRM) program, a four-stage process of using information to identify opportunities for improvement, developing an effective resource management team, implementing process improvement activities, and measuring the impact on outcomes of care. CASE STUDY EXAMPLE--CONGESTIVE HEART FAILURE: The chair of the departments of internal medicine and family practice selected congestive heart failure for in-depth study. A task force focused on treatment and patient disposition in the emergency room (ER), where most of the nonelective admissions originated. A set of standardized ER orders was developed that emphasized rapid and effective diuresis through the initiation of a progressive diuretic dosing schedule directly linked to patient response. Factors critical to the success of the CRM program included allocating adequate time to promote and sell the value and importance of the program, as well as securing the support of both information systems and physicians. The main barriers to success involved limitations in the information system infrastructure and delays attributable to committee review. Short-term results from the CRM program were encouraging, with average lengths of stay reduced by 0.5 days and average costs of care reduced by 12% for the ten diagnoses studied with no adverse results. Nonstudy diagnoses showed no notable improvement. Recognizing the growing importance of information management not only for clinical decision support but for accommodating all the necessary internal and external reporting requirements will require a significant commitment and investment in technology and personnel resources.

  5. 36 CFR 261.3 - Interfering with a Forest officer, volunteer, or human resource program enrollee or giving false...

    Science.gov (United States)

    2010-07-01

    ... officer, volunteer, or human resource program enrollee or giving false report to a Forest officer. 261.3... General Prohibitions § 261.3 Interfering with a Forest officer, volunteer, or human resource program..., intimidating, or intentionally interfering with any Forest officer, volunteer, or human resource program...

  6. Waste resources utilization program. Progress report, period ending 30 June 1975

    International Nuclear Information System (INIS)

    1975-08-01

    Initial progress on the Waste Resources Utilization Program, a joint effort sponsored by ERDA and EPA under the terms of Interagency Agreement E(29-2)-3536/EPA-IAG-D5-0675 is reported. This program has as its objective the use of 134 Cs/ 137 Cs (a potential nuclear reactor ''waste resource'') as a gamma radiation source, coupled with modest heating, to treat sewage sludge (another ''waste resource'') to rid it of pathogenic organisms so that it may be safely used as a fertilizer or a feed supplement for ruminant animals. The potential exists for using at least 50 percent of the by-product cesium from future reactor fuel-rod reprocessing in this one application alone. Activities dealing with research on many aspects of the problem such as pathogen reduction, physical and chemical effects, cost benefit analysis, safety and security, and systems engineering are reported. (U.S.)

  7. Deoxypodophyllotoxin suppresses tumor vasculature in HUVECs by promoting cytoskeleton remodeling through LKB1-AMPK dependent Rho A activatio.

    Science.gov (United States)

    Wang, Yurong; Wang, Bin; Guerram, Mounia; Sun, Li; Shi, Wei; Tian, Chongchong; Zhu, Xiong; Jiang, Zhenzhou; Zhang, Luyong

    2015-10-06

    Angiogenesis plays a critical role in the growth and metastasis of tumors, which makes it an attractive target for anti-tumor drug development. Deoxypodophyllotoxin (DPT), a natural product isolated from Anthriscus sylvestris, inhibits cell proliferation and migration in various cancer cell types. Our previous studies indicate that DPT possesses both anti-angiogenic and vascular-disrupting activities. Although the RhoA/ RhoA kinase (ROCK) signaling pathway is implicated in DPT-stimulated cytoskeleton remodeling and tumor vasculature suppressing, the detailed mechanisms by which DPT mediates these effects are poorly understood. In the current study, we found that DPT promotes cytoskeleton remodeling in human umbilical vein endothelial cells (HUVECs) via stimulation of AMP-activated protein kinase (AMPK) and that this effect is abolished by either treatment with a selective AMPK inhibitor or knockdown. Moreover, the cellular levels of LKB1, a kinase upstream of AMPK, were enhanced following DPT exposure. DPT-induced activation of AMPK in tumor vasculature effect was also verified by transgenic zebrafish (VEGFR2:GFP), Matrigel plug assay, and xenograft model in nude mice. The present findings may lay the groundwork for a novel therapeutic approach in treating cancer.

  8. High-level Programming and Symbolic Reasoning on IoT Resource Constrained Devices

    Directory of Open Access Journals (Sweden)

    Sal vatore Gaglio

    2015-05-01

    Full Text Available While the vision of Internet of Things (IoT is rather inspiring, its practical implementation remains challenging. Conventional programming approaches prove unsuitable to provide IoT resource constrained devices with the distributed processing capabilities required to implement intelligent, autonomic, and self-organizing behaviors. In our previous work, we had already proposed an alternative programming methodology for such systems that is characterized by high-level programming and symbolic expressions evaluation, and developed a lightweight middleware to support it. Our approach allows for interactive programming of deployed nodes, and it is based on the simple but e ective paradigm of executable code exchange among nodes. In this paper, we show how our methodology can be used to provide IoT resource constrained devices with reasoning abilities by implementing a Fuzzy Logic symbolic extension on deployed nodes at runtime.

  9. Inexact Multistage Stochastic Chance Constrained Programming Model for Water Resources Management under Uncertainties

    Directory of Open Access Journals (Sweden)

    Hong Zhang

    2017-01-01

    Full Text Available In order to formulate water allocation schemes under uncertainties in the water resources management systems, an inexact multistage stochastic chance constrained programming (IMSCCP model is proposed. The model integrates stochastic chance constrained programming, multistage stochastic programming, and inexact stochastic programming within a general optimization framework to handle the uncertainties occurring in both constraints and objective. These uncertainties are expressed as probability distributions, interval with multiply distributed stochastic boundaries, dynamic features of the long-term water allocation plans, and so on. Compared with the existing inexact multistage stochastic programming, the IMSCCP can be used to assess more system risks and handle more complicated uncertainties in water resources management systems. The IMSCCP model is applied to a hypothetical case study of water resources management. In order to construct an approximate solution for the model, a hybrid algorithm, which incorporates stochastic simulation, back propagation neural network, and genetic algorithm, is proposed. The results show that the optimal value represents the maximal net system benefit achieved with a given confidence level under chance constraints, and the solutions provide optimal water allocation schemes to multiple users over a multiperiod planning horizon.

  10. Laboratory and field studies related to the Hydrologic Resources Management Program

    International Nuclear Information System (INIS)

    Thompson, J.L.; Hawkins, W.L.; Mathews, M.; Henderson, R.W.; Thompson, J.L.; Maestas, S.

    1994-01-01

    This report describes research done at Los Alamos in FY 1993 for the Hydrologic Resources Management Program. The US Department of Energy funds this research through two programs at the Nevada Test Site (NTS): defense and groundwater characterization. Los Alamos personnel have continued to study the high-pressure zone created in the aquifer under Yucca Flat. We analyzed data from a hole in this area (U-7cd) and drilled another hole and installed a water monitoring tube at U-4t. We analyzed water from a number of locations on the NTS where we know there are radionuclides in the groundwater and critiqued the effectiveness of this monitoring effort. Our program for analyzing postshot debris continued with material from the last nuclear test in September 1992. We supported both the defense program and the groundwater characterization program by analyzing water samples from their wells and by reviewing documents pertaining to future drilling. We helped develop the analytical methodology to be applied to water samples obtained in the environmental restoration and waste management efforts at the NTS. Los Alamos involvement in the Hydrologic Resources Management Program is reflected in the appended list of documents reviewed, presentations given, papers published, and meetings attended

  11. Gulf Coast geopressured-geothermal program summary report compilation. Volume 2-A: Resource description, program history, wells tested, university and company based research, site restoration

    Energy Technology Data Exchange (ETDEWEB)

    John, C.J.; Maciasz, G.; Harder, B.J.

    1998-06-01

    The US Department of Energy established a geopressured-geothermal energy program in the mid 1970`s as one response to America`s need to develop alternate energy resources in view of the increasing dependence on imported fossil fuel energy. This program continued for 17 years and approximately two hundred million dollars were expended for various types of research and well testing to thoroughly investigate this alternative energy source. This volume describes the following studies: Geopressured-geothermal resource description; Resource origin and sediment type; Gulf Coast resource extent; Resource estimates; Project history; Authorizing legislation; Program objectives; Perceived constraints; Program activities and structure; Well testing; Program management; Program cost summary; Funding history; Resource characterization; Wells of opportunity; Edna Delcambre No. 1 well; Edna Delcambre well recompletion; Fairfax Foster Sutter No. 2 well; Beulah Simon No. 2 well; P.E. Girouard No. 1 well; Prairie Canal No. 1 well; Crown Zellerbach No. 2 well; Alice C. Plantation No. 2 well; Tenneco Fee N No. 1 well; Pauline Kraft No. 1 well; Saldana well No. 2; G.M. Koelemay well No. 1; Willis Hulin No. 1 well; Investigations of other wells of opportunity; Clovis A. Kennedy No. 1 well; Watkins-Miller No. 1 well; Lucien J. Richard et al No. 1 well; and the C and K-Frank A. Godchaux, III, well No. 1.

  12. Surplus Facilities and Resource Conservation and Recovery Act Closure program plan, fiscal year 1992

    International Nuclear Information System (INIS)

    Hughes, M.C.; Wahlen, R.K.; Winship, R.A.

    1991-10-01

    The Surplus Facilities and Resource Conservation and Recovery Act Closure program is responsible to US Department of Energy Field Office, Richland for the safe, cost-effective surveillance, maintenance, and decommissioning of surplus facilities at the Hanford Site. The Surplus Facilities and Resource Conservation and Recovery Act Closure program is also responsible to US Department of Energy Field Office, Richland for the program management of specific Resource Conservation and Recovery Act closures at the Hanford Site. This program plan addresses only the surplus facilities. The criteria used to evaluate each factor relative to decommissioning are based on the guidelines presented by the US Department of Energy Field Office, Richland, Environmental Restoration Division. The guidelines are consistent with the Westinghouse Hanford Company commitment to decommission Hanford Site retired facilities in the safest and most cost-effective way achievable. This document outlines the plan for managing these facilities until disposal

  13. Disruption of Fyn SH3 domain interaction with a proline-rich motif in liver kinase B1 results in activation of AMP-activated protein kinase.

    Directory of Open Access Journals (Sweden)

    Eijiro Yamada

    Full Text Available Fyn-deficient mice display increased AMP-activated Protein Kinase (AMPK activity as a result of Fyn-dependent regulation of Liver Kinase B1 (LKB1 in skeletal muscle. Mutation of Fyn-specific tyrosine sites in LKB1 results in LKB1 export into the cytoplasm and increased AMPK activation site phosphorylation. This study characterizes the structural elements responsible for the physical interaction between Fyn and LKB1. Effects of point mutations in the Fyn SH2/SH3 domains and in the LKB1 proline-rich motif on 1 Fyn and LKB1 binding, 2 LKB1 subcellular localization and 3 AMPK phosphorylation were investigated in C2C12 muscle cells. Additionally, novel LKB1 proline-rich motif mimicking cell permeable peptides were generated to disrupt Fyn/LKB1 binding and investigate the consequences on AMPK activity in both C2C12 cells and mouse skeletal muscle. Mutation of either Fyn SH3 domain or the proline-rich motif of LKB1 resulted in the disruption of Fyn/LKB1 binding, re-localization of 70% of LKB1 signal in the cytoplasm and a 2-fold increase in AMPK phosphorylation. In vivo disruption of the Fyn/LKB1 interaction using LKB1 proline-rich motif mimicking cell permeable peptides recapitulated Fyn pharmacological inhibition. We have pinpointed the structural elements within Fyn and LKB1 that are responsible for their binding, demonstrating the functionality of this interaction in regulating AMPK activity.

  14. The wind resource assessment program in Quebec Canada

    Energy Technology Data Exchange (ETDEWEB)

    Kahawita, R.; Bilodeau, L.; Gaudette, M.; Gratton, Y.; Noel, R.; Quach, T.T.

    1982-09-01

    This paper provides an overview of the wind resource assessment programme undertaken by the provincial power utility Hydro-Quebec, in Quebec, Canada. The methodology used in different phases of the project is enunciated and explained and the results discussed. Supplementary studies of airflow over complex terrain using numerical modelling are described and the results evaluated. Since the program is still far from completion, conclusive statements cannot, at this time, be made about the viability of the wind energy resource. However, tentative conclusions are that wind energy as an alternate source of energy for the province is likely to be commerciaally viable since two of the most important requirements viz, the presence of a good wind regime and the availability of suitable land are satisfied in many regions.

  15. Recommended Resources for Planning to Evaluate Program Improvement Efforts (Including the SSIP)

    Science.gov (United States)

    National Center for Systemic Improvement at WestEd, 2015

    2015-01-01

    This document provides a list of recommended existing resources for state Part C and Part B 619 staff and technical assistance (TA) providers to utilize to support evaluation planning for program improvement efforts (including the State Systemic Improvement Plan, SSIP). There are many resources available related to evaluation and evaluation…

  16. Programs and resources for control of job stress in the Federal workplace

    Science.gov (United States)

    Joice, Wendell

    1993-01-01

    A couple of weeks ago, the American Psychological Association and the National Institute of Occupational Safety and Health held a conference in Washingtion, D.C. entitled 'Stress in the 90's'. At this conference the Office of Personnel Management (OPM) conducted a session on 'Programs and Resources for the Control of Job Stress in the Federal Workplace'. I am going to present an overview of that three-hour session and some related information from the conference. My discussion covers stress terminology and models, selected programs and resources, evaluation research, some concerns about our progress, and plans to expand our efforts at OPM.

  17. Program-oriented approach to resource saving issues in construction materials industry

    Directory of Open Access Journals (Sweden)

    Novikova Galina

    2017-01-01

    Full Text Available The construction as a sector of the economy is one of the largest consumers of energy resources, and the building materials industry is today one of the most energy-intensive construction industry. At the enterprises of the building materials industry the different approaches and methods are used to solve resource and energy problems. Energy saving is considered not as an complex approach in the enterprise activity, but as activity for the implementation of specific energy-saving projects, which have limitations in time and in resources. The authors suggest to use a softwareoriented approach to solving the problems of resource and energy saving. For practical application of program-oriented approach we offer to use a structuring method of the decision-making, not previously used to solve problems of resource and energy saving.

  18. Hawaii energy strategy project 3: Renewable energy resource assessment and development program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    RLA Consulting (RLA) has been retained by the State of Hawaii Department of Business, Economic Development and Tourism (DBEDT) to conduct a Renewable Energy Resource Assessment and Development Program. This three-phase program is part of the Hawaii Energy Strategy (HES), which is a multi-faceted program intended to produce an integrated energy strategy for the State of Hawaii. The purpose of Phase 1 of the project, Development of a Renewable Energy Resource Assessment Plan, is to better define the most promising potential renewable energy projects and to establish the most suitable locations for project development in the state. In order to accomplish this goal, RLA has identified constraints and requirements for renewable energy projects from six different renewable energy resources: wind, solar, biomass, hydro, wave, and ocean thermal. These criteria were applied to areas with sufficient resource for commercial development and the results of Phase 1 are lists of projects with the most promising development potential for each of the technologies under consideration. Consideration of geothermal energy was added to this investigation under a separate contract with DBEDT. In addition to the project lists, a monitoring plan was developed with recommended locations and a data collection methodology for obtaining additional wind and solar data. This report summarizes the results of Phase 1. 11 figs., 22 tabs.

  19. Resource letter for Accelerated Matter Program

    International Nuclear Information System (INIS)

    Rossi, F.

    1989-07-01

    This resource letter covers diverse literature(400 titles) relevant to the Accelerated Matter Program in the Particles and Fields Group at the University of Melbourne. Specifically, the research areas covered are: inertia induced electric fields in accelerated matter; strain induced contact potentials; the patch effect/surface potentials. There are no claims made for completeness. The areas of gravity, acceleration and strain induced effects in matter, and drift tube experiments with matter/antimatter are extensively covered, if not complete. The literature on acceleration/inertia induced effects in metals has a long history dating back to the 19th century and the reader is referred to the review by Barnett (1935) for an extensive list of references not included here. All other work following this 1935 review, has been included here. The literature on surface physics is very extensive and no attempt has been made to cover it all. Every major paper on metal surfaces has been cited. Several other references have been included which fall only loosely into the above areas and they represent useful and/or interesting material for this research program

  20. Adopting De Novo Programming Approach on IC Design Service Firms Resources Integration

    Directory of Open Access Journals (Sweden)

    James K. C. Chen

    2014-01-01

    Full Text Available The semiconductor industry has very important position in computer industry, ICT field, and new electronic technology developing. The IC design service is one of key factor of semiconductor industry development. There are more than 365 IC design service firms have been established around Hsinchu Science Park in Taiwan. Building an efficient planning model for IC design service firm resources integrating is very interest issue. This study aims to construct a planning model for IC design service firm implementation resources integration. This study uses the De Novo programming as an approach of criteria alternative to achieve optimal resource allocation on IC design firm. Results show the IC design service firm should conduct open innovation concept and utilizes design outsourcing obtains cost down and enhance IC design service business performance. This plan model of De Novo programming is not only for IC design service firm and also can apply to the other industrial implementation strategic alliance/integrating resource. This plan model is a universal model for the others industries field.

  1. Human Resources Requirements for New Nuclear Power Programs

    International Nuclear Information System (INIS)

    Goodnight, Charles T.

    2014-01-01

    Summary: Planning to Meet HR Requirements for New Nuclear Power Programs Must Begin Early. Many years of preparation are required before the “Right Number of the Right People” … will be … “In the Right Place at the Right Time”. • Seven key steps which must be taken include: 1) Identify detailed Human Resources requirements, based on the selected site and reactor design; 2) Conduct an assessment of national capacity to develop and/or provide those resources; 3) Conduct a Gap Analysis to determine what additional steps will be needed to fill any capacity shortfalls; 4) Develop initial and recurring recruiting and training plans; 5) Begin recruiting and training; 6) Review and adjust as personnel move and/or leave; 7) Ensure adequate relationships are in place for sources of future recruiting

  2. Parent Couples' Coping Resources and Involvement in their Children's Intervention Program.

    Science.gov (United States)

    Brand, Devora; Zaidman-Zait, Anat; Most, Tova

    2018-07-01

    Parental involvement is vital to the implementation of intervention programs for deaf and hard-of-hearing (DHH) children. The current study examined the dyadic relationships between mothers' and fathers' coping resources and their involvement in their child's intervention program. In addition, the moderating roles of parent's gender and family religiosity on the associations between coping resources and involvement were examined. Seventy Jewish couples of parents of DHH children, representing various levels of religiosity, completed questionnaires regarding involvement in their child's intervention program, child acceptance, parental self-efficacy, and perceived social support. Multilevel modeling analyses were used to test actor-partner interdependence. The findings indicated significant actor effects for child acceptance, parental self-efficacy, and social support. All were positively associated with parental involvement. Gender was found to moderate the actor effect of child acceptance. Partner effects were found only for mothers, for child acceptance, and social support. Fathers' child acceptance and social support were negatively associated with mothers' involvement. Religiosity did not moderate neither actor nor partner effects. These results have important implications for planning intervention programs that are sensitive to each of the parent's needs.

  3. Resource allocation decision modeling for a Louisiana Public Benefit Fund program

    International Nuclear Information System (INIS)

    Kaiser, Mark J.; Pulsipher, Allan G.

    2003-01-01

    A simulation model is developed to value energy efficiency improvement programs in Louisiana proposed to be delivered through a Public Benefits Fund. A uniform 1 mill/kW h non-bypassable surcharge on the electric rates of all electricity users is proposed to be distributed for low-income bill assistance, low-income weatherization, and energy efficiency programs across the residential and commercial sector of Louisiana. The economic and environmental impact of the energy improvement programs is coupled to a stochastic linear program to specify the resource allocation subject to policy and system constraints. The model is illustrated through a realistic policy scenario. (Author)

  4. Macrophage Liver Kinase B1 Inhibits Foam Cell Formation and Atherosclerosis.

    Science.gov (United States)

    Liu, Zhaoyu; Zhu, Huaiping; Dai, Xiaoyan; Wang, Cheng; Ding, Ye; Song, Ping; Zou, Ming-Hui

    2017-10-13

    LKB1 (liver kinase B1) is a serine/threonine kinase and tumor suppressor, which regulates the homeostasis of hematopoietic cells and immune responses. Macrophages transform into foam cells upon taking-in lipids. No role for LKB1 in foam cell formation has previously been reported. We sought to establish the role of LKB1 in atherosclerotic foam cell formation. LKB1 expression was examined in human carotid atherosclerotic plaques and in western diet-fed atherosclerosis-prone Ldlr -/- and ApoE -/- mice. LKB1 expression was markedly reduced in human plaques when compared with nonatherosclerotic vessels. Consistently, time-dependent reduction of LKB1 levels occurred in atherosclerotic lesions in western diet-fed Ldlr -/- and ApoE -/- mice. Exposure of macrophages to oxidized low-density lipoprotein downregulated LKB1 in vitro. Furthermore, LKB1 deficiency in macrophages significantly increased the expression of SRA (scavenger receptor A), modified low-density lipoprotein uptake and foam cell formation, all of which were abolished by blocking SRA. Further, we found LKB1 phosphorylates SRA resulting in its lysosome degradation. To further investigate the role of macrophage LKB1 in vivo, ApoE -/- LKB1 fl/fl LysM cre and ApoE -/- LKB1 fl/fl mice were fed with western diet for 16 weeks. Compared with ApoE -/- LKB1 fl/fl wild-type control, ApoE -/- LKB1 fl/fl LysM cre mice developed more atherosclerotic lesions in whole aorta and aortic root area, with markedly increased SRA expression in aortic root lesions. We conclude that macrophage LKB1 reduction caused by oxidized low-density lipoprotein promotes foam cell formation and the progression of atherosclerosis. © 2017 American Heart Association, Inc.

  5. Learned Resourcefulness and the Long-Term Benefits of a Chronic Pain Management Program

    Science.gov (United States)

    Kennett, Deborah J.; O'Hagan, Fergal T.; Cezer, Diego

    2008-01-01

    A concurrent mixed methods approach was used to understand how learned resourcefulness empowers individuals. After completing Rosenbaum's Self-Control Schedule (SCS) measuring resourcefulness, 16 past clients of a multimodal pain clinic were interviewed about the kinds of pain-coping strategies they were practicing from the program. Constant…

  6. National Uranium Resource Evaluation Program. Hydrogeochemical and Stream Sediment Reconnaissance Basic Data Reports Computer Program Requests Manual

    International Nuclear Information System (INIS)

    1980-01-01

    This manual is intended to aid those who are unfamiliar with ordering computer output for verification and preparation of Uranium Resource Evaluation (URE) Project reconnaissance basic data reports. The manual is also intended to help standardize the procedures for preparing the reports. Each section describes a program or group of related programs. The sections are divided into three parts: Purpose, Request Forms, and Requested Information

  7. Implementation of the program for conservation and sustainable utilization of forest genetic resources in Republic of Serbia

    Directory of Open Access Journals (Sweden)

    Šijačić-Nikolić Mirjana

    2017-01-01

    Full Text Available Program for conservation and sustainable utilization of forest genetic resources has been defined for 2016-2025 period and it is a base for concrete activities in this field. This Program could be divided into several parts that deal with: the legal framework for the conservation and sustainable utilization of forest genetic resources; status of forest genetic resources in Serbia; previous activities on the conservation of forest genetic resources; and objectives, priorities and measures of conservation. The Program should have an impact on the development of the forestry sector through the following activities: conservation and sustainable utilization of the available gene pool; improving forest management in accordance with conservation principles; improving the production of reproductive material of forest trees; make the public awareness of the need for conservation and sustainable utilization of forest genetic resources; fulfillment of international obligations related to this field and the possibility of joining FAO activities related to forest genetic resources - development of the national report as a part of the publication The State of the World's Forest Genetic Resources. Implementation of the Program will depend upon raising the awareness on the importance, conservation and sustainable utilization of forest genetic resources, as a precondition for the forests survival; it will depend of funds that will be allocated for this purpose and enthusiasm of people who deal with these issues.

  8. Human resources in nuclear power program

    International Nuclear Information System (INIS)

    Machi, Sueo

    2008-01-01

    plant or nuclear power plant manufacture. Newly hired graduates or technical personnel working in industry undergo further training. Those working for the NPP manufactures undergo training in designs, manufacturing and construction while those working with the power companies undertake plant operation training using simulator, plant maintenance, safety culture and design specification. A survey of newly hired BS and MS graduates in engineering by power companies for nuclear power sector in Japan showed that 221 graduates were hired in 1997 and the number dropped to 134 in 1999 and maintained this level up to 2001. These engineering graduates majored in electronics, nuclear, chemistry, mechanics and others. Meanwhile, 30% of the engineering graduates hired by 3 major NPP manufactures for their NPP division are nuclear engineers while the other 70% consists of engineers majoring in mechanics, electronics, materials and other majors. The number of staff for NPP division will have to be increased in future to meet increased demand in Japan and overseas. The human resource development for nuclear energy is faced with the dilemma because the young generation is losing interest in science and technology and many experienced nuclear engineers are retiring and there is a decreasing number of new construction of NPPs till 2030. Possible solutions are to improve public perception on nuclear power, ensure effective succession of nuclear knowledge and experience to young engineers and technicians, strengthen R and D on generationIV NPP and Fast Breeder Reactors (FBR), and strengthen nuclear education and training. In support of this human resource development, the Japanese government provided funding of US$3.4 million in 2007. Within the framework of the Forum for Nuclear Cooperation in Asia (FNCA), the Asian Nuclear Training and Education Program (ANTEP) has the following objectives: (1) to train and educate nuclear engineers and scientists and specialists of radiation applications

  9. Using Innovative Resources and Programs to Prepare Pre- and In-Service Teachers for New Science Standards

    Science.gov (United States)

    Kinzler, R. J.; Short, J.; Contino, J.; Cooke-Nieves, N.; Howes, E.; Kravitz, D.; Randle, D.; Trowbridge, C.

    2014-12-01

    Leveraging the Rose Center for Earth and Space and active research departments in Earth and Planetary Science, Astrophysics, and Paleontology, the Education Department at the American Museum of Natural History (AMNH) offers an MAT program to prepare new Earth Science teachers (~100 new teachers by 2018) as well as a range of professional development (PD) opportunities for over 3,000 K-12 teachers annually, providing opportunities to learn with scientists; inquiry-based experiences; and standards-aligned resources. The AMNH produces innovative geoscience and other STEM resources supporting teacher and student science investigations with data visualizations and analysis tools, teaching case materials and other resources that provide rich nonfiction reading and writing opportunities for use in Earth and space science curricula that are integrated in the MAT and PD programs. Museum resources and the MAT and PD programs are aligned to support the recently released Next Generation Science Standards (NGSS) and the Common Core State Standards. The NGSS is a set of science and engineering practices, crosscutting concepts and disciplinary core ideas to help cultivate teachers' and K-12 students' scientific habits of mind, develop their knowledge and abilities to engage in scientific investigations, and teach them how to reason in context; goals that closely align with those of the AMNH's teacher preparation and professional development programs. A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas (NRC, 2012) is a required text for the MAT program, and this text as well as the NGSS Performance Expectations guide the PD programs as well. Researchers working with Museum scientists and educators find it is not enough for programs for pre- and in-service teachers to provide access to resources. Research suggests that these programs need to engage pre- and in-service teachers in using and reflecting on these types of resources, as well as take

  10. A taxonomy for community-based care programs focused on HIV/AIDS prevention, treatment, and care in resource-poor settings.

    Science.gov (United States)

    Rachlis, Beth; Sodhi, Sumeet; Burciul, Barry; Orbinski, James; Cheng, Amy H Y; Cole, Donald

    2013-04-16

    Community-based care (CBC) can increase access to key services for people affected by HIV/AIDS through the mobilization of community interests and resources and their integration with formal health structures. Yet, the lack of a systematic framework for analysis of CBC focused on HIV/AIDS impedes our ability to understand and study CBC programs. We sought to develop taxonomy of CBC programs focused on HIV/AIDS in resource-limited settings in an effort to understand their key characteristics, uncover any gaps in programming, and highlight the potential roles they play. Our review aimed to systematically identify key CBC programs focused on HIV/AIDS in resource-limited settings. We used both bibliographic database searches (Medline, CINAHL, and EMBASE) for peer-reviewed literature and internet-based searches for gray literature. Our search terms were 'HIV' or 'AIDS' and 'community-based care' or 'CBC'. Two co-authors developed a descriptive taxonomy through an iterative, inductive process using the retrieved program information. We identified 21 CBC programs useful for developing taxonomy. Extensive variation was observed within each of the nine categories identified: region, vision, characteristics of target populations, program scope, program operations, funding models, human resources, sustainability, and monitoring and evaluation strategies. While additional research may still be needed to identify the conditions that lead to overall program success, our findings can help to inform our understanding of the various aspects of CBC programs and inform potential logic models for CBC programming in the context of HIV/AIDS in resource-limited settings. Importantly, the findings of the present study can be used to develop sustainable HIV/AIDS-service delivery programs in regions with health resource shortages.

  11. Augmentation of Water Resources Potential and Cropping Intensification Through Watershed Programs.

    Science.gov (United States)

    Mondal, Biswajit; Singh, Alka; Singh, S D; Kalra, B S; Samal, P; Sinha, M K; Ramajayam, D; Kumar, Suresh

    2018-02-01

      This paper presents the biophysical impact of various interventions made under watershed development programs, in terms of the creation of additional water resources, and resultant changes in land use and cropping patterns in the Bundelkhand region of Madhya Pradesh State, India. Both primary and secondary data gathered from randomly selected watersheds and their corresponding control villages were used in this study. Analysis revealed that emphasis was given primarily to the creation of water resources potential during implementation of the programs, which led to augmentation of surface and groundwater availability for both irrigation and non-agricultural purposes. In addition, other land based interventions for soil and moisture conservation, plantation activities, and so forth, were taken up on both arable and nonarable land, which helped to improve land slope and land use, cropping pattern, agricultural productivity, and vegetation cover.

  12. University of Idaho Water of the West Initiative: Development of a sustainable, interdisciplinary water resources program

    Science.gov (United States)

    Boll, J.; Cosens, B.; Fiedler, F.; Link, T.; Wilson, P.; Harris, C.; Tuller, M.; Johnson, G.; Kennedy, B.

    2006-12-01

    Recently, an interdisciplinary group of faculty from the University of Idaho was awarded a major internal grant for their project "Water of the West (WoW)" to launch an interdisciplinary Water Resources Graduate Education Program. This Water Resources program will facilitate research and education to influence both the scientific understanding of the resource and how it is managed, and advance the decision-making processes that are the means to address competing societal values. By educating students to integrate environmental sciences, socio-economic, and political issues, the WoW project advances the University's land grant mission to promote economic and social development in the state of Idaho. This will be accomplished through novel experiential interdisciplinary education activities; creation of interdisciplinary research efforts among water resources faculty; and focusing on urgent regional problems with an approach that will involve and provide information to local communities. The Water Resources Program will integrate physical and biological sciences, social science, law, policy and engineering to address problems associated with stewardship of our scarce water resources. As part of the WoW project, faculty will: (1) develop an integrative problem-solving framework; (2) develop activities to broaden WR education; (3) collaborate with the College of Law to offer a concurrent J.D. degree, (4) develop a virtual system of watersheds for teaching and research, and (5) attract graduate students for team-based education. The new program involves 50 faculty from six colleges and thirteen departments across the university. This university-wide initiative is strengthened by collaboration with the Idaho Water Resources Research Institute, and participation from off-campus Centers in Idaho Falls, Boise, Twin Falls, and Coeur d'Alene. We hope this presentation will attract university faculty, water resources professionals, and others for stimulating discussions on

  13. National Uranium Resource Evaluation Program: the Hydrogeochemical Stream Sediment Reconnaissance Program at LLNL

    International Nuclear Information System (INIS)

    Higgins, G.H.

    1980-08-01

    From early 1975 to mid 1979, Lawrence Livermore National Laboratory (LLNL) participated in the Hydrogeochemical Stream Sediment Reconnaissance (HSSR), part of the National Uranium Resource Evaluation (NURE) program sponsored by the Department of Energy (DOE). The Laboratory was initially responsible for collecting, analyzing, and evaluating sediment and water samples from approximately 200,000 sites in seven western states. Eventually, however, the NURE program redefined its sampling priorities, objectives, schedules, and budgets, with the increasingly obvious result that LLNL objectives and methodologies were not compatible with those of the NURE program office, and the LLNL geochemical studies were not relevant to the program goal. The LLNL portion of the HSSR program was consequently terminated, and all work was suspended by June 1979. Of the 38,000 sites sampled, 30,000 were analyzed by instrumental neutron activation analyses (INAA), delayed neutron counting (DNC), optical emission spectroscopy (OES), and automated chloride-sulfate analyses (SC). Data from about 13,000 sites have been formally reported. From each site, analyses were published of about 30 of the 60 elements observed. Uranium mineralization has been identified at several places which were previously not recognized as potential uranium source areas, and a number of other geochemical anomalies were discovered

  14. GateWay Community College Water Resources Program Partnerships: An Opportunity for Program Success and Collaboration

    Science.gov (United States)

    Castaneda, M.

    2012-12-01

    GateWay Community College Water Resources Technologies (WRT) Program offers Certificate of Completions and Associate Degrees on Hydrologic Studies, Water Treatment and Wastewater Treatment. The program has been in existence since 1998 and has gone through several updates to meet the demand for professionals in those areas. The program includes theoretical and practical hands-on training in the monitoring of water quality and quantity as well as in water and industrial wastewater treatment. The WRT program offers online, face-to-face, and hybrid courses to address different student's needs for training. The program only Full-time faculty is supported by 15 adjunct- faculty professionals. Adjunct faculty is usually hired from a wide variety of professional people already working in the industry that have shown interest on teaching. Adjunct faculty also provide free tutoring to the WRT students when they are not teaching courses. The college Learning Center provides funding to support these tutoring activities. The program has an active Advisory Committee that provides guidance and recommends program changes to meet their training needs. This Advisory Committee is made of professionals from different federal, state, county agencies, and municipalities, private industry and consulting companies in the area. The Advisory Committee meets every year to provide feedback to GateWay on curriculum changes and commit to potential internship opportunities for the WRT students. Those internships (or voluntary work) are paid directly by the municipalities or agencies or can be paid by the GateWay WRT program. These internship jobs provides with an opportunity to actively promote the WRT program throughout the valley. The GateWay WRT program considers the Advisory Committee an essential component for the program success: the committee supports the program in recommending and acquiring the latest field equipment needed for the hands-on training. One of the main WRT program

  15. Integrating human resources and program-planning strategies.

    Science.gov (United States)

    Smith, J E

    1989-06-01

    The integration of human resources management (HRM) strategies with long-term program-planning strategies in hospital pharmacy departments is described. HRM is a behaviorally based, comprehensive strategy for the effective management and use of people that seeks to achieve coordination and integration with overall planning strategies and other managerial functions. It encompasses forecasting of staffing requirements; determining work-related factors that are strong "motivators" and thus contribute to employee productivity and job satisfaction; conducting a departmental personnel and skills inventory; employee career planning and development, including training and education programs; strategies for promotion and succession, including routes of advancement that provide alternatives to the managerial route; and recruitment and selection of new personnel to meet changing departmental needs. Increased competitiveness among hospitals and a shortage of pharmacists make it imperative that hospital pharmacy managers create strategies to attract, develop, and retain the right individuals to enable the department--and the hospital as a whole--to grow and change in response to the changing health-care environment in the United States. Pharmacy managers would be greatly aided in this mission by the establishment of a well-defined, national strategic plan for pharmacy programs and services that includes an analysis of what education and training are necessary for their successful accomplishment. Creation of links between overall program objectives and people-planning strategies will aid hospital pharmacy departments in maximizing the long-term effectiveness of their practice.

  16. Risk Management for Study Abroad Programs: Issues and Resources to Inform Program Development, Administration, and Training

    Science.gov (United States)

    Rhodes, Gary

    2014-01-01

    This chapter provides a practical background to the health and safety risks and challenges for U.S. colleges and universities and other program providers. Potential risks, field-based guidelines, good practices, and resources to support the management of risks by study abroad offices will be covered.

  17. A taxonomy for community-based care programs focused on HIV/AIDS prevention, treatment, and care in resource-poor settings

    Directory of Open Access Journals (Sweden)

    Beth Rachlis

    2013-04-01

    Full Text Available Community-based care (CBC can increase access to key services for people affected by HIV/AIDS through the mobilization of community interests and resources and their integration with formal health structures. Yet, the lack of a systematic framework for analysis of CBC focused on HIV/AIDS impedes our ability to understand and study CBC programs. We sought to develop taxonomy of CBC programs focused on HIV/AIDS in resource-limited settings in an effort to understand their key characteristics, uncover any gaps in programming, and highlight the potential roles they play. Our review aimed to systematically identify key CBC programs focused on HIV/AIDS in resource-limited settings. We used both bibliographic database searches (Medline, CINAHL, and EMBASE for peer-reviewed literature and internet-based searches for gray literature. Our search terms were ‘HIV’ or ‘AIDS’ and ‘community-based care’ or ‘CBC’. Two co-authors developed a descriptive taxonomy through an iterative, inductive process using the retrieved program information. We identified 21 CBC programs useful for developing taxonomy. Extensive variation was observed within each of the nine categories identified: region, vision, characteristics of target populations, program scope, program operations, funding models, human resources, sustainability, and monitoring and evaluation strategies. While additional research may still be needed to identify the conditions that lead to overall program success, our findings can help to inform our understanding of the various aspects of CBC programs and inform potential logic models for CBC programming in the context of HIV/AIDS in resource-limited settings. Importantly, the findings of the present study can be used to develop sustainable HIV/AIDS-service delivery programs in regions with health resource shortages.

  18. Ethical considerations in resource allocation in a cochlear implant program.

    Science.gov (United States)

    Westerberg, Brian D; Pijl, Sipke; McDonald, Michael

    2008-04-01

    To review processes of resource allocation and the ethical considerations relevant to the fair allocation of a limited number of cochlear implants to increasing numbers of potential recipients. Review of relevant considerations. Tertiary referral hospital. Editorial discussion of the ethical issues of resource allocation. Heterogeneity of audiometric thresholds, self-reported disability of hearing loss, age of the potential cochlear implant recipient, cost-effectiveness, access to resources, compliance with follow-up, social support available to the recipient, social consequences of hearing impairment, and other recipient-related factors. In a publicly funded health care system, there will always be a need for decision-making processes for allocation of finite fiscal resources. All candidates for cochlear implantation deserve fair consideration. However, they are a heterogeneous group in terms of needs and expected outcomes consisting of traditional and marginal candidates, with a wide range of benefit from acoustic amplification. We argue that implant programs should thoughtfully prioritize treatment on the basis of need and potential benefit. We reject queuing on the basis of "first-come, first-served" or on the basis of perceived social worth.

  19. Resource Contingency Program : Draft Environmental Impact Statement.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1995-02-01

    In 1990, the Bonneville Power Administration (BPA) embarked upon the Resource Contingency Program (RCP) to fulfill its statutory responsibilities to supply electrical power to its utility, industrial and other customers in the Pacific Northwest. Instead of buying or building generating plants now, BPA has purchased options to acquire power later if needed. Three option development agreements were signed in September 1993 with three proposed natural gas-fired, combined cycle combustion turbine CT projects near Chehalis and Satsop Washington and near Hermiston, Oregon. This environmental impact statement addresses the environmental consequences of purchasing power from these options. This environmental impact statement addresses the environmental consequences of purchasing power from these options.

  20. [Overexpression of liver kinase B1 inhibits the proliferation of lung cancer cells].

    Science.gov (United States)

    Li, Yang; Zhang, Libin; Wang, Ping

    2017-01-01

    Objective To explore the effect of overexpressed liver kinase B1(LKB1) on the proliferation of lung cancer cell lines. Methods The expression levels of LKB1 and PTEN in A549, NCI-H23, NCI-H157, XWLC-05, NCI-H446 lung cancer cells were detected by immunocytochemistry (ICC) and Western blotting. Plasmid pcDNA3.1 + -LKB1 and empty vector pcDNA3.1 + -null were separately transfected into the above five cell lines, and then the expression of LKB1 mRNA and protein were determined by quantitative real-time PCR and Western blotting, respectively. Finally, CCK-8 assay was used to analyze the proliferation ability of the transfected cells. Results LKB1 and PTEN were positive in NCI-H23 cells; LKB1 was negative while PTEN was positive in A549 and NCI-H446 cells; both LKB1 and PTEN were negative in NCI-H157 and XWLC-05 cells. Quantitative real-time PCR and Western blotting showed that the expression level of LKB1 significantly increased in the above cell lines transfected with plasmid pcDNA3.1 + -LKB1 compared with the ones with empty vector pcDNA3.1 + -null. Besides, CCK-8 assay showed that the overexpression of LKB1 in the lung cancer cells transfected with pcDNA3.1 + -LKB1 had an obvious inhibitory effect on cell proliferation. Conclusion The expression of LKB1 is down-regulated in most of the lung cell lines to different extent and the over-expression of LKB1 can remarkably inhibit the proliferation ability of lung cancer cell lines.

  1. Information resources for US Department of Energy pollution prevention programs

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, K.L.; Snowden-Swan, L.J.; Butner, R.S.

    1994-01-01

    In support of the US Department of Energy`s (DOE`s) pollution prevention efforts being conducted under the aegis of DOE`s Office of Environmental Restoration and Waste Management (EM) program, Pacific Northwest Laboratory was tasked with evaluating pollution prevention information resources. The goal of this activity was to improve the effectiveness of DOE`s pollution prevention activities through improved information flow, both within the complex, and more specifically, between DOE and other organizations that share similar pollution prevention challenges. This report presents our findings with respect to the role of information collection and dissemination within the complex, opportunities for teaming from successes of the private sector, and specific information needs of the DOE pollution prevention community. These findings were derived from a series of interviews with pollution prevention coordinators from across the DOE complex, review of DOE site and facility pollution prevention plans, and workshops with DOE information users as well as an information resources workshop that brought together information specialists from private industry, non-profit organizations, as well as state and regional pollution prevention assistance programs.

  2. U.S. Geological Survey water-resources programs in New Mexico, FY 2015

    Science.gov (United States)

    Mau, David P.

    2015-01-01

    The U.S. Geological Survey (USGS) has collected hydrologic information in New Mexico since 1889, beginning with the first USGS streamflow-gaging station in the Nation, located on the Rio Grande near Embudo, New Mexico. Water-resources information provided by the USGS is used by many government agencies for issuing flood warnings to protect lives and reduce property damage,managing water rights and interstate water use, protecting water quality and regulating pollution discharges, designing highways and bridges, planning, designing, and operating reservoirs and watersupply facilities, monitoring the availability of groundwater resources and forecasting aquifer response to human and environmental stressors, and prioritizing areas where emergency erosion mitigation or other protective measures may be necessary after a wildfire. For more than 100 years, the Cooperative Water Program has been a highly successful cost-sharing partnership between the USGS and water-resources agencies at the State, local, and tribal levels. It would be difficult to effectively accomplish the mission of the USGS without the contributions of the Cooperative Water Program.

  3. Human resource management in the Georgian National Immunization Program: a baseline assessment

    OpenAIRE

    Cohen-Kohler Jillian; Esmail Laura C; Djibuti Mamuka

    2007-01-01

    Abstract Background Georgia's health care system underwent dramatic reform after gaining independence in 1991. The decentralization of the health care system was one of the core elements of health care reform but reports suggest that human resource management issues were overlooked. The Georgian national immunization program was affected by these reforms and is not functioning at optimum levels. This paper describes the state of human resource management practices within the Georgian national...

  4. Human resource management in the Georgian National Immunization Program: a baseline assessment

    Directory of Open Access Journals (Sweden)

    Cohen-Kohler Jillian

    2007-07-01

    Full Text Available Abstract Background Georgia's health care system underwent dramatic reform after gaining independence in 1991. The decentralization of the health care system was one of the core elements of health care reform but reports suggest that human resource management issues were overlooked. The Georgian national immunization program was affected by these reforms and is not functioning at optimum levels. This paper describes the state of human resource management practices within the Georgian national immunization program in late 2004. Methods Thirty districts were selected for the study. Within these districts, 392 providers and thirty immunization managers participated in the study. Survey questionnaires were administered through face-to-face interviews to immunization managers and a mail survey was administered to immunization providers. Qualitative data collection involved four focus groups. Analysis of variance (ANOVA and Chi-square tests were used to test for differences between groups for continuous and categorical variables. Content analysis identified main themes within the focus groups. Results Weak administrative links exist between the Centres of Public Health (CPH and Primary Health Care (PHC health facilities. There is a lack of clear management guidelines and only 49.6% of all health providers had written job descriptions. A common concern among all respondents was the extremely inadequate salary. Managers cited lack of authority and poor knowledge and skills in human resource management. Lack of resources and infrastructure were identified as major barriers to improving immunization. Conclusion Our study found that the National Immunization Program in Georgia was characterized by weak organizational structure and processes and a lack of knowledge and skills in management and supervision, especially at peripheral levels. The development of the skills and processes of a well-managed workforce may help improve immunization rates, facilitate

  5. Human resource management in the Georgian National Immunization Program: a baseline assessment.

    Science.gov (United States)

    Esmail, Laura C; Cohen-Kohler, Jillian Clare; Djibuti, Mamuka

    2007-07-31

    Georgia's health care system underwent dramatic reform after gaining independence in 1991. The decentralization of the health care system was one of the core elements of health care reform but reports suggest that human resource management issues were overlooked. The Georgian national immunization program was affected by these reforms and is not functioning at optimum levels. This paper describes the state of human resource management practices within the Georgian national immunization program in late 2004. Thirty districts were selected for the study. Within these districts, 392 providers and thirty immunization managers participated in the study. Survey questionnaires were administered through face-to-face interviews to immunization managers and a mail survey was administered to immunization providers. Qualitative data collection involved four focus groups. Analysis of variance (ANOVA) and Chi-square tests were used to test for differences between groups for continuous and categorical variables. Content analysis identified main themes within the focus groups. Weak administrative links exist between the Centres of Public Health (CPH) and Primary Health Care (PHC) health facilities. There is a lack of clear management guidelines and only 49.6% of all health providers had written job descriptions. A common concern among all respondents was the extremely inadequate salary. Managers cited lack of authority and poor knowledge and skills in human resource management. Lack of resources and infrastructure were identified as major barriers to improving immunization. Our study found that the National Immunization Program in Georgia was characterized by weak organizational structure and processes and a lack of knowledge and skills in management and supervision, especially at peripheral levels. The development of the skills and processes of a well-managed workforce may help improve immunization rates, facilitate successful implementation of remaining health care reforms and

  6. Preparing Future Geoscience Professionals: Needs, Strategies, Programs, and Online Resources

    Science.gov (United States)

    Macdonald, H.; Manduca, C. A.; Ormand, C. J.; Dunbar, R. W.; Beane, R. J.; Bruckner, M.; Bralower, T. J.; Feiss, P. G.; Tewksbury, B. J.; Wiese, K.

    2011-12-01

    Geoscience faculty, departments, and programs play an important role in preparing future geoscience professionals. One challenge is supporting the diversity of student goals for future employment and the needs of a wide range of potential employers. Students in geoscience degree programs pursue careers in traditional geoscience industries; in geoscience education and research (including K-12 teaching); and opportunities at the intersection of geoscience and other fields (e.g., policy, law, business). The Building Strong Geoscience Departments project has documented a range of approaches that departments use to support the development of geoscience majors as professionals (serc.carleton.edu/departments). On the Cutting Edge, a professional development program, supports graduate students and post-doctoral fellows interested in pursuing an academic career through workshops, webinars, and online resources (serc.carleton.edu/NAGTWorkshops/careerprep). Geoscience departments work at the intersection of student interests and employer needs. Commonly cited program goals that align with employer needs include mastery of geoscience content; field experience; skill in problem solving, quantitative reasoning, communication, and collaboration; and the ability to learn independently and take a project from start to finish. Departments and faculty can address workforce issues by 1) implementing of degree programs that develop the knowledge, skills, and attitudes that students need, while recognizing that students have a diversity of career goals; 2) introducing career options to majors and potential majors and encouraging exploration of options; 3) advising students on how to prepare for specific career paths; 4) helping students develop into professionals, and 5) supporting students in the job search. It is valuable to build connections with geoscience employers, work with alumni and foster connections between students and alumni with similar career interests, collaborate with

  7. An inexact mixed risk-aversion two-stage stochastic programming model for water resources management under uncertainty.

    Science.gov (United States)

    Li, W; Wang, B; Xie, Y L; Huang, G H; Liu, L

    2015-02-01

    Uncertainties exist in the water resources system, while traditional two-stage stochastic programming is risk-neutral and compares the random variables (e.g., total benefit) to identify the best decisions. To deal with the risk issues, a risk-aversion inexact two-stage stochastic programming model is developed for water resources management under uncertainty. The model was a hybrid methodology of interval-parameter programming, conditional value-at-risk measure, and a general two-stage stochastic programming framework. The method extends on the traditional two-stage stochastic programming method by enabling uncertainties presented as probability density functions and discrete intervals to be effectively incorporated within the optimization framework. It could not only provide information on the benefits of the allocation plan to the decision makers but also measure the extreme expected loss on the second-stage penalty cost. The developed model was applied to a hypothetical case of water resources management. Results showed that that could help managers generate feasible and balanced risk-aversion allocation plans, and analyze the trade-offs between system stability and economy.

  8. Application of systems engineering methods to the development of information resource management programs

    International Nuclear Information System (INIS)

    Hofer, R.W.

    1987-01-01

    The Civilian Radioactive Waste Management program has presented challenges to information professionals which have never been confronted before. This is the first major research program to require full public access to a vast range of scientific and engineering data. Estimated information system life cycle requirements commensurate with the repository's 10,000 year life are unprecedented, especially when compared with the needs of the commercial nuclear industry. The range of information system users and the differences in the ability of various classes of users to access sophisticated information resources has likewise never been approached in this area before. Consequently, application of previous experience associated with the commercial nuclear power industry information system design falls far short of meeting the information management and dissemination requirements of this program. This paper describes the overall information requirements governing the data and documents associated with the site characterization phase of the geologic repository program. It further outlines a design methodology for the development of an information resource management program which responds to these criteria, emphasizing the use of a systems engineering approach. The paper concludes with a projection of future requirements for information management associated with the geologic repository program and suggested approaches to planning for these needs

  9. An Introduction to "My Environmental Education Evaluation Resource Assistant" (MEERA), a Web-Based Resource for Self-Directed Learning about Environmental Education Program Evaluation

    Science.gov (United States)

    Zint, Michaela

    2010-01-01

    My Environmental Education Evaluation Resource Assistant or "MEERA" is a web-site designed to support environmental educators' program evaluation activities. MEERA has several characteristics that set it apart from other self-directed learning evaluation resources. Readers are encouraged to explore the site and to reflect on the role that…

  10. U.S. Geological Survey cooperative water-resources programs in Chester County, Pennsylvania

    Science.gov (United States)

    Wood, Charles R.

    1998-01-01

    Since 1969, the U.S. Geological Survey (USGS) has had a cooperative water-resources investigation program with Chester County to measure and describe the water resources of the County. Generally, the USGS provides one-half of the program funding, and local cooperators are required to provide matching funds. Cooperation has been primarily with the Chester County Water Resources Authority (CCWRA), with participation from the Chester County Health Department and funding from the Chester County Board of Commissioners. Municipalities and the Red Clay Valley Association also have provided part of the funding for several projects. This report describes how the long-term partnership between the USGS and Chester County, Pa., provides the County with the information that it needs for sound water-resources management.The CCWRA was created in 1961, primarily for land acquisition and planning for flood-control and water-supply projects. With the backing of the Brandywine Valley Association, the CCWRA started its first cooperative project with the USGS in 1969. It was a study of the water-quality condition of Chester County streams with an emphasis on benthic macroinvertebrates and stream chemistry.The kinds of projects and data collection conducted by the USGS have changed with the needs of Chester County and the mission of the CCWRA. Chester County is experiencing rapid population growth (it had the tenth-highest rate of growth in the nation from 1980 to 1990). This growth places considerable stress on water resources and has caused the CCWRA to broaden its focus from flood control to water-supply planning, water quality, and ground-water and surface-water management. The results of USGS studies are used by the CCWRA and other County agencies, including the Planning Commission, Health Department, and Parks and Recreation Department, for conducting day-to-day activities and planning for future growth. The results also are used by the CCWRA to provide guidance and technical

  11. Resource allocation within the National AIDS Control Program of Pakistan: a qualitative assessment of decision maker's opinions

    Directory of Open Access Journals (Sweden)

    Kadir Masood

    2007-01-01

    Full Text Available Abstract Background Limited resources, whether public or private, demand prioritisation among competing needs to maximise productivity. With a substantial increase in the number of reported HIV cases, little work has been done to understand how resources have been distributed and what factors may have influenced allocation within the newly introduced Enhanced National AIDS Control Program of Pakistan. The objective of this study was to identify perceptions of decision makers about the process of resource allocation within Pakistan's Enhanced National AIDS Control Program. Methods A qualitative study was undertaken and in-depth interviews of decision makers at provincial and federal levels responsible to allocate resources within the program were conducted. Results HIV was not considered a priority issue by all study participants and external funding for the program was thought to have been accepted because of poor foreign currency reserves and donor agency influence rather than local need. Political influences from the federal government and donor agencies were thought to manipulate distribution of funds within the program. These influences were thought to occur despite the existence of a well-laid out procedure to determine allocation of public resources. Lack of collaboration among departments involved in decision making, a pervasive lack of technical expertise, paucity of information and an atmosphere of ad hoc decision making were thought to reduce resistance to external pressures. Conclusion Development of a unified program vision through a consultative process and advocacy is necessary to understand goals to be achieved, to enhance program ownership and develop consensus about how money and effort should be directed. Enhancing public sector expertise in planning and budgeting is essential not just for the program, but also to reduce reliance on external agencies for technical support. Strengthening available databases for effective

  12. Resource allocation within the National AIDS Control Program of Pakistan: a qualitative assessment of decision maker's opinions.

    Science.gov (United States)

    Husain, Sara; Kadir, Masood; Fatmi, Zafar

    2007-01-23

    Limited resources, whether public or private, demand prioritisation among competing needs to maximise productivity. With a substantial increase in the number of reported HIV cases, little work has been done to understand how resources have been distributed and what factors may have influenced allocation within the newly introduced Enhanced National AIDS Control Program of Pakistan. The objective of this study was to identify perceptions of decision makers about the process of resource allocation within Pakistan's Enhanced National AIDS Control Program. A qualitative study was undertaken and in-depth interviews of decision makers at provincial and federal levels responsible to allocate resources within the program were conducted. HIV was not considered a priority issue by all study participants and external funding for the program was thought to have been accepted because of poor foreign currency reserves and donor agency influence rather than local need. Political influences from the federal government and donor agencies were thought to manipulate distribution of funds within the program. These influences were thought to occur despite the existence of a well-laid out procedure to determine allocation of public resources. Lack of collaboration among departments involved in decision making, a pervasive lack of technical expertise, paucity of information and an atmosphere of ad hoc decision making were thought to reduce resistance to external pressures. Development of a unified program vision through a consultative process and advocacy is necessary to understand goals to be achieved, to enhance program ownership and develop consensus about how money and effort should be directed. Enhancing public sector expertise in planning and budgeting is essential not just for the program, but also to reduce reliance on external agencies for technical support. Strengthening available databases for effective decision making is required to make financial allocations based on real

  13. Strategic innovation between PhD and DNP programs: Collaboration, collegiality, and shared resources.

    Science.gov (United States)

    Edwards, Joellen; Rayman, Kathleen; Diffenderfer, Sandra; Stidham, April

    2016-01-01

    At least 111 schools and colleges of nursing across the nation provide both PhD and DNP programs (AACN, 2014a). Collaboration between nurses with doctoral preparation as researchers (PhD) and practitioners (DNP) has been recommended as essential to further the profession; that collaboration can begin during the educational process. The purpose of this paper is to describe the development and implementation of successful DNP and PhD program collaboration, and to share the results of that collaboration in an educational setting. Faculty set strategic goals to maximize the effectiveness and efficiency of both new DNP and existing PhD programs. The goals were to promote collaboration and complementarity between the programs through careful capstone and dissertation differentiation, complementary residency activities, joint courses and inter-professional experiences; promote collegiality in a blended on-line learning environment through shared orientation and intensive on-campus sessions; and maximize resources in program delivery through a supportive organizational structure, equal access to technology support, and shared faculty responsibilities as appropriate to terminal degrees. Successes such as student and faculty accomplishments, and challenges such as managing class size and workload, are described. Collaboration, collegiality and the sharing of resources have strengthened and enriched both programs and contributed to the success of students, faculty. These innovative program strategies can provide a solid foundation for DNP and PhD collaboration. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. A LINEAR PROGRAMMING METHOD TO ENHANCE RESOURCE UTILIZATION CASE OF ETHIOPIAN APPAREL SECTOR

    Directory of Open Access Journals (Sweden)

    Gezahegn Tesfaye

    2016-06-01

    Full Text Available The Ethiopian industrial development strategy is characterized by export-led and labor intensive industrialization. The country is emerging as the most important investment destination in its apparel sector. Thought this sector is expected to generate more income from the export market, its export earnings remain trivial mainly due to the inefficient organizational resource utilization. One of the competent techniques that help companies to efficiently improve the use of their resources to increase their profit is linear programming. In apparel manufacturing firms, efficient use of materials such as fabrics and sewing threads and processing time at different stages of production as well as minimization of labor and materials cost are necessary to enhance their profitability. Cutting, sewing, and finishing operations deserve more attention for apparel process optimization. However, the issue of proper resource allocation remains an unsolved problem within the Ethiopian apparel industry. The aim of this research is to devise efficient resource utilization mechanism for Ethiopian apparel sector to improve their resource utilization and profitability, taking one of the garment factories engaged in the export market as a case study. Five types of products the company is currently producing, the amount of resources employed to produce each unit of the products, and the value of profit per unit from the sale of each products have been collected from the case company. The monthly availability of resources utilized and the monthly production volume of the five products have also been collected from the company. The data gathered was mathematically modeled using a linear programming technique, and solved using MS-Excel solver. The findings of the study depicts that all of the organizational resources are severely underutilized. This research proved that the resource utilization of the case company can be improved from 46.41% of the current resource

  15. Evaluation of a Music Therapy Social Skills Development Program for Youth with Limited Resources.

    Science.gov (United States)

    Pasiali, Varvara; Clark, Cherie

    2018-05-21

    Children living in low-resource communities are at risk for poorer socio-emotional development and academic performance. Emerging evidence supports use of group music therapy experiences to support social development through community afterschool programming. To examine the potential benefit of a music therapy social skills development program to improve social skills and academic performance of school-aged children with limited resources in an afterschool program. We used a single-group pre/post-test design, and recruited 20 students (11 females, 9 males), ages 5 to 11 years, from an afterschool program. The music therapy social skills program consisted of eight 50-minute sessions, and we measured social competence and antisocial behavior using the Home & Community Social Behavioral Scale (HCSBS; Merrell & Caldarella, 2008), and social skills, problem behaviors, and academic competence using the Social Skills Improvement System (SSIS; Gresham & Elliot, 2008a, 2008b). Only students who attended a minimum of six sessions (N = 14) were included in data analysis. Results showed no significant change in individual HBSC subscale scores; however, the total number of low-performance/high-risk skills significantly decreased. SSIS teacher results indicated significant improvement in communication, significant decrease of hyperactivity, autistic behavioral tendencies and overall problem behaviors, and marginal decreases in internalization. Parent ratings mirrored, in part, those of the teacher. Results indicated that music therapy has the potential of being an effective intervention for promoting social competence of school-aged children with limited resources, particularly in the areas of communication and low-performance/high-risk behaviors. Teaching skills through song lyrics and improvisation emerged as salient interventions.

  16. NGSS aligned Earth science resources and professional development programs from the Exploratorium.

    Science.gov (United States)

    Muller, E.

    2016-12-01

    The Exploratorium is a museum of science, art and human perception located in San Francisco, CA. The Exploratorium has been offering resources and professional development to primary and secondary teachers since 1972. We focus on inquiry based, hands-on learning, with an emphasis on Next Generation Science Standards (NGSS) implementation. This brief, invited presentation will feature the programs and online resources developed by the Exploratorium's "Institute for Inquiry" and "Teacher Institute" that may help formal and informal educators engage, implement and promote three dimensional learning in the Earth Sciences.

  17. Remote sensing programs and courses in engineering and water resources

    Science.gov (United States)

    Kiefer, R. W.

    1981-01-01

    The content of typical basic and advanced remote sensing and image interpretation courses are described and typical remote sensing graduate programs of study in civil engineering and in interdisciplinary environmental remote sensing and water resources management programs are outlined. Ideally, graduate programs with an emphasis on remote sensing and image interpretation should be built around a core of five courses: (1) a basic course in fundamentals of remote sensing upon which the more specialized advanced remote sensing courses can build; (2) a course dealing with visual image interpretation; (3) a course dealing with quantitative (computer-based) image interpretation; (4) a basic photogrammetry course; and (5) a basic surveying course. These five courses comprise up to one-half of the course work required for the M.S. degree. The nature of other course work and thesis requirements vary greatly, depending on the department in which the degree is being awarded.

  18. Strategic Plan for the U.S. Geological Survey. Status and Trends of Biological Resources Program: 2004-2009

    National Research Council Canada - National Science Library

    Dresler, Paul V; James, Daniel L; Geissler, Paul H; Bartish, Timothy M; Coyle, James

    2004-01-01

    The mission of the USGS Status and Trends of Biological Resources Program is to measure, predict, assess, and report the status and trends of the Nation's biological resources to facilitate research...

  19. United States Geological Survey uranium and thorium resource assessment and exploration research program, fiscal year 1980

    International Nuclear Information System (INIS)

    Offield, T.W.

    1979-01-01

    Research is being conducted by the USGS for the NURE program in six fields: geochemistry and mineralogy, sedimentary environments, igneous and metamorphic environments, geophysical exploration techniques, U resource assessment, and Th resource assessment. Some FY 1979 research results are reported and discussed

  20. A Critical Evaluation on Programming Paradigms to Achieve Optimal Resource Utilization of Mobile Softwares in Mobile Devices

    OpenAIRE

    Selvakumar Samuel; Arangasamy Kovalan

    2014-01-01

    This paper evaluates the features of mainstream programming paradigms. Imperative, object oriented programming and functional programming concepts are considered here. This is an effort to identify the programming paradigms which consume less resource from mobile devices. Designers usually depend on the programming languages, language oriented programming design is in current practice. Choosing appropriate programming paradigms during the mobile application design is not in practice now; Fail...

  1. DYNAMIC PROGRAMMING APPROACH TO TESTING RESOURCE ALLOCATION PROBLEM FOR MODULAR SOFTWARE

    Directory of Open Access Journals (Sweden)

    P.K. Kapur

    2003-02-01

    Full Text Available Testing phase of a software begins with module testing. During this period modules are tested independently to remove maximum possible number of faults within a specified time limit or testing resource budget. This gives rise to some interesting optimization problems, which are discussed in this paper. Two Optimization models are proposed for optimal allocation of testing resources among the modules of a Software. In the first model, we maximize the total fault removal, subject to budgetary Constraint. In the second model, additional constraint representing aspiration level for fault removals for each module of the software is added. These models are solved using dynamic programming technique. The methods have been illustrated through numerical examples.

  2. Use of Online Information Resources by RMIT University Economics, Finance, and Marketing Students Participating in a Cooperative Education Program

    Science.gov (United States)

    Costa, Cathy

    2009-01-01

    This paper examines the use of online information resources by Economics, Finance, and Marketing 3rd year students in a cooperative education program and explores some possible factors and issues that influence how students use these resources. The nature of Work Integrated Learning (WIL) programs, the business information environment, and the…

  3. Geothermal direct heat program: roundup technical conference proceedings. Volume II. Bibliography of publications. State-coupled geothermal resource assessment program

    Energy Technology Data Exchange (ETDEWEB)

    Ruscetta, C.A. (ed.)

    1982-07-01

    Lists of publications are presented for the Geothermal Resource Assessment Program for the Utah Earth Science Laboratory and the following states: Alaska, Arizona, California, Colorado, Hawaii, Idaho, Kansas, Montana, Nebraska, Nevada, New Mexico, New York, North Dakota, Oregon, Texas, Utah, and Washington.

  4. Stochastic-based resource expansion planning for a grid-connected microgrid using interval linear programming

    International Nuclear Information System (INIS)

    Shaban Boloukat, Mohammad Hadi; Akbari Foroud, Asghar

    2016-01-01

    This paper represents a stochastic approach for long-term optimal resource expansion planning of a grid-connected microgrid (MG) containing different technologies as intermittent renewable energy resources, energy storage systems and thermal resources. Maximizing profit and reliability, along with minimizing investment and operation costs, are major objectives which have been considered in this model. Also, the impacts of intermittency and uncertainty in renewable energy resources were investigated. The interval linear programming (ILP) was applied for modelling inherent stochastic nature of the renewable energy resources. ILP presents some superiority in modelling of uncertainties in MG planning. The problem was formulated as a mixed-integer linear programming. It has been demonstrated previously that the benders decomposition (BD) served as an effective tool for solving such problems. BD divides the original problem into a master (investment) problem and operation and reliability subproblems. In this paper a multiperiod MG planning is presented, considering life time, maximum penetration limit of each technology, interest rate, capital recovery factor and investment fund. Real-time energy exchange with the utility is covered, with a consideration of variable tariffs at different load blocks. The presented approach can help MG planners to adopt best decision under various uncertainty levels based on their budgetary policies. - Highlights: • Considering uncertain nature of the renewable resources with applying ILP. • Considering the effect of intermittency of renewable in MG planning. • Multiobjective MG planning problem which covers cost, profit and reliability. • Multiperiod approach for MG planning considering life time and MPL of technologies. • Presenting real-time energy exchange with the utility considering variable tariffs.

  5. Geology and mineral resources of the Florence, Beaufort, Rocky Mount, and Norfolk 10 x 20 NTMS quadrangles. National Uranium Resource Evaluation program

    International Nuclear Information System (INIS)

    Harris, W.B.

    1982-08-01

    This document provides geologic and mineral resources data for previously-issued Savannah River Laboratory hydrogeochemical and stream sediment reports of the Beaufort, Florence, Norfolk, and Rocky Mount 1 0 x 2 0 National Topographic Map Series quadrangles in the southeastern United States. This report is issued in draft form, without detailed technical and copy editing. This was done to make the report available to the public before the end of the National Uranium Resource Evaluation program

  6. Fiscal Year 1988 program report: Rhode Island Water Resources Center

    International Nuclear Information System (INIS)

    Poon, C.P.C.

    1989-07-01

    The State of Rhode Island is active in water resources planning, development, and management activities which include legislation, upgrading of wastewater treatment facilities, upgrading and implementing pretreatment programs, protecting watersheds and aquifers throughout the state. Current and anticipated state water problems are contamination and clean up of aquifers to protect the valuable groundwater resources; protection of watersheds by controlling non-point source pollution; development of pretreatment technologies; and deterioring groundwater quality from landfill leachate or drainage from septic tank leaching field. Seven projects were included covering the following subjects: (1) Radon and its nuclei parents in bedrocks; (2) Model for natural flushing of aquifer; (3) Microbial treatment of heavy metals; (4) Vegetative uptake of nitrate; (5) Microbial process in vegetative buffer strips; (6) Leachate characterization in landfills; and (7) Electrochemical treatment of heavy metals and cyanide

  7. Implementing antiretroviral therapy programs in resource-constrained settings: lessons from Monze, Zambia.

    Science.gov (United States)

    Adedimeji, Adebola; Malokota, Oliver; Manafa, Ogenna

    2011-05-01

    We describe the impact of an antiretroviral therapy program on human resource utilization and service delivery in a rural hospital in Monze, Zambia, using qualitative data. We assess project impact on staff capacity utilization, service delivery, and community perception of care. Increased workload resulted in fatigue, low staff morale, and exacerbated critical manpower shortages, but also an increase in users of antiretroviral therapy, improvement in hospital infrastructure and funding, and an overall community satisfaction with service delivery. Integrating HAART programs within existing hospital units and services may be a good alternative to increase overall efficiency.

  8. 1995 Annual wildlife survey report. Natural Resource Protection and Compliance Program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-25

    This report summarizes the results of wildlife surveys performed at Rocky Flats Environmental Technology Site (RFETS) from January through December of 1995 as compared with results from previous years. These surveys were performed as part of a long-term ecological monitoring program conducted under the Natural Resource Protection and Compliance Program (NRPCP). This program is essential in identifying and describing fluctuations of wildlife populations, wildlife habitat use, and changes in species using RFETS. The NRPCP provides support to the Department of Energy (DOE) in its role as Natural Resource Trustee, and provides data essential to accomplishing the goal of preserving the unique ecological values of RFETS in keeping with the Rocky Flats Vision presented in the Rocky Flats Cleanup Agreement Public Comment Draft. Wildlife population densities vary due to natural pressures and human influences, and only long-term monitoring can verify which factors influencing wildlife populations are the consequence of natural fluctuations, and which are due to human influences. The wildlife monitoring described in this report provides qualitative data that give an indication of the ecological health of RFETS. Monitoring numbers, habitat affinities, and apparent health of the wildlife populations makes it possible to evaluate the overall ecological health of the site. Monitoring and surveys such as those carried out by the NRPCP can indicate trends of this sort, and act as an {open_quotes}early warning system{close_quotes} for impending ecological problems.

  9. An Interval-Parameter Fuzzy Linear Programming with Stochastic Vertices Model for Water Resources Management under Uncertainty

    Directory of Open Access Journals (Sweden)

    Yan Han

    2013-01-01

    Full Text Available An interval-parameter fuzzy linear programming with stochastic vertices (IFLPSV method is developed for water resources management under uncertainty by coupling interval-parameter fuzzy linear programming (IFLP with stochastic programming (SP. As an extension of existing interval parameter fuzzy linear programming, the developed IFLPSV approach has advantages in dealing with dual uncertainty optimization problems, which uncertainty presents as interval parameter with stochastic vertices in both of the objective functions and constraints. The developed IFLPSV method improves upon the IFLP method by allowing dual uncertainty parameters to be incorporated into the optimization processes. A hybrid intelligent algorithm based on genetic algorithm and artificial neural network is used to solve the developed model. The developed method is then applied to water resources allocation in Beijing city of China in 2020, where water resources shortage is a challenging issue. The results indicate that reasonable solutions have been obtained, which are helpful and useful for decision makers. Although the amount of water supply from Guanting and Miyun reservoirs is declining with rainfall reduction, water supply from the South-to-North Water Transfer project will have important impact on water supply structure of Beijing city, particularly in dry year and extraordinary dry year.

  10. A Guide to Outdoor Education Resources and Programs for the Handicapped. Outdoor Education for the Handicapped.

    Science.gov (United States)

    Kentucky Univ., Lexington.

    The resource guide is designed to assist educators, park resource persons, and parents of disabled children in locating and identifying sources of information for developing, implementing, and evaluating outdoor education programs for all disabled children and youth. The guide has two main parts. The first part contains an annotated bibliography…

  11. Resource Allocation Optimization Model of Collaborative Logistics Network Based on Bilevel Programming

    Directory of Open Access Journals (Sweden)

    Xiao-feng Xu

    2017-01-01

    Full Text Available Collaborative logistics network resource allocation can effectively meet the needs of customers. It can realize the overall benefit maximization of the logistics network and ensure that collaborative logistics network runs orderly at the time of creating value. Therefore, this article is based on the relationship of collaborative logistics network supplier, the transit warehouse, and sellers, and we consider the uncertainty of time to establish a bilevel programming model with random constraints and propose a genetic simulated annealing hybrid intelligent algorithm to solve it. Numerical example shows that the method has stronger robustness and convergence; it can achieve collaborative logistics network resource allocation rationalization and optimization.

  12. Resource Review: Youth and Adult Leaders for Program Excellence: A Practical Guide for Program Assessment and Action Planning

    Directory of Open Access Journals (Sweden)

    Hartley Hobson

    2007-03-01

    Full Text Available The Youth and Adult Leaders for Program Excellence (YALPE Resource Kit was developed to assist groups working to promote positive youth development. The Kit includes a variety of assessment tools and templates for data analysis and report writing. The tools are grounded in research on youth development and are user-friendly for adults and youth.

  13. Site study plan for cultural resources, Deaf Smith County site, Texas: Environmental Field Program: Preliminary draft

    International Nuclear Information System (INIS)

    1987-06-01

    The Cultural Resources Site Study Plan describes a field program to identify and evaluate the archaeological, historical, and Native American Indian resources of the site on local and regional perspectives; monitor and manage discovered cultural resources; and establish a worker education program. The archaeological field program consists of three pedestrian surveys: Survey 1 includes two EDBH seismic survey lines and the area within the exploratory shaft facility (ESF); Survey 2 includes the remainder of the site plus a 1/4 to 3/4-mi border area; and Survey 3 includes an assortment of offsite areas. The historical studies will identify and evaluate known and discovered historical sites and structures and the Native American Indian will identify and evaluate cultural and religious concerns expressed by Indian tribal groups. Prehistoric and historic sites will be evaluated to determine if they meet eligibility criteria for listing on the National Register of Historic Places. This site study plan describes the need for each study; its design and design rationale; analysis, management, and use of data; schedule of field activities; organization of field personnel and sample management; and quality assurance requirements. The cultural resource studies will provide data for satisfying the Programmatic Agreement, engineering design needs, and SRP requirements for permits and approvals, and for minimizing effects to any cultural properties discovered during site characterization. 75 refs., 10 figs., 2 tabs

  14. Energy resource allocation using multi-objective goal programming: the case of Lebanon

    International Nuclear Information System (INIS)

    Mezher, T.; Chedid, R.; Zahabi, W.

    1998-01-01

    The traditional energy-resources allocation problem is concerned with the allocation of limited resources among the end-uses such that the overall return is maximized. In the past, several techniques have been used to deal with such a problem. In this paper, the energy allocation process is looked at from two points of view: economy and environment. The economic objectives include costs, efficiency, energy conservation, and employment generation. The environmental objectives consider environmental friendliness factors. The objective functions are first quantified and then transformed into mathematical language to obtain a multi-objective allocation model based upon pre-emptive goal programming techniques. The proposed method allows decision-makers to encourage or discourage specific energy resources for the various household end-uses. The case of Lebanon is examined to illustrate the usefulness of the proposed technique. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

  15. Long Term Resource Monitoring Program procedures: fish monitoring

    Science.gov (United States)

    Ratcliff, Eric N.; Glittinger, Eric J.; O'Hara, T. Matt; Ickes, Brian S.

    2014-01-01

    This manual constitutes the second revision of the U.S. Army Corps of Engineers’ Upper Mississippi River Restoration-Environmental Management Program (UMRR-EMP) Long Term Resource Monitoring Program (LTRMP) element Fish Procedures Manual. The original (1988) manual merged and expanded on ideas and recommendations related to Upper Mississippi River fish sampling presented in several early documents. The first revision to the manual was made in 1995 reflecting important protocol changes, such as the adoption of a stratified random sampling design. The 1995 procedures manual has been an important document through the years and has been cited in many reports and scientific manuscripts. The resulting data collected by the LTRMP fish component represent the largest dataset on fish within the Upper Mississippi River System (UMRS) with more than 44,000 collections of approximately 5.7 million fish. The goal of this revision of the procedures manual is to document changes in LTRMP fish sampling procedures since 1995. Refinements to sampling methods become necessary as monitoring programs mature. Possible refinements are identified through field experiences (e.g., sampling techniques and safety protocols), data analysis (e.g., planned and studied gear efficiencies and reallocations of effort), and technological advances (e.g., electronic data entry). Other changes may be required because of financial necessity (i.e., unplanned effort reductions). This version of the LTRMP fish monitoring manual describes the most current (2014) procedures of the LTRMP fish component.

  16. Preference and Priority in Federal Funding: Aligning Federal Resources to Maximize Program Investment Efficiency and Impacts in Communities

    Science.gov (United States)

    This page contains the document, Preference and Priority in Federal Funding: Aligning Federal Resources to Maximize Program Investment Efficiency and Impacts in Communities - Lessons from EPA’s Brownfields Program.

  17. Wind resource assessment handbook: Fundamentals for conducting a successful monitoring program

    International Nuclear Information System (INIS)

    Bailey, B.H.; McDonald, S.L.; Bernadett, D.W.; Markus, M.J.; Elsholz, K.V.

    1997-01-01

    This handbook presents industry-accepted guidelines for planning and conducting a wind resource measurement program to support a wind energy feasibility initiative. These guidelines, which are detailed and highly technical, emphasize the tasks of selecting, installing, and operating wind measurement equipment, as well as collecting and analyzing the associated data, once one or more measurement sites are located. The handbook's scope encompasses state-of-the-art measurement and analysis techniques at multiple heights on tall towers (e.g., 40 m) for a measurement duration of at least one year. These guidelines do not represent every possible method of conducting a quality wind measurement program, but they address the most important elements based on field-proven experience. The intended audience for this handbook is any organization or individual who desires the planning framework and detailed procedures for conducting a formally structured wind measurement program. Personnel from the management level to field technicians will find this material applicable. The organizational aspects of a measurement program, including the setting of clear program objectives and designing commensurate measurement and quality assurance plans, all of which are essential to ensuring the program's successful outcome, are emphasized. Considerable attention is also given to the details of actually conducting the measurement program in its many aspects, from selecting instrumentation that meets minimum performance standards to analyzing and reporting on the collected data. 5 figs., 15 tabs

  18. Liver kinase B1 inhibits the expression of inflammation-related genes postcontraction in skeletal muscle.

    Science.gov (United States)

    Chen, Ting; Moore, Timothy M; Ebbert, Mark T W; McVey, Natalie L; Madsen, Steven R; Hallowell, David M; Harris, Alexander M; Char, Robin E; Mackay, Ryan P; Hancock, Chad R; Hansen, Jason M; Kauwe, John S; Thomson, David M

    2016-04-15

    Skeletal muscle-specific liver kinase B1 (LKB1) knockout mice (skmLKB1-KO) exhibit elevated mitogen-activated protein kinase (MAPK) signaling after treadmill running. MAPK activation is also associated with inflammation-related signaling in skeletal muscle. Since exercise can induce muscle damage, and inflammation is a response triggered by damaged tissue, we therefore hypothesized that LKB1 plays an important role in dampening the inflammatory response to muscle contraction, and that this may be due in part to increased susceptibility to muscle damage with contractions in LKB1-deficient muscle. Here we studied the inflammatory response and muscle damage with in situ muscle contraction or downhill running. After in situ muscle contractions, the phosphorylation of both NF-κB and STAT3 was increased more in skmLKB1-KO vs. wild-type (WT) muscles. Analysis of gene expression via microarray and RT-PCR shows that expression of many inflammation-related genes increased after contraction only in skmLKB1-KO muscles. This was associated with mild skeletal muscle fiber membrane damage in skmLKB1-KO muscles. Gene markers of oxidative stress were also elevated in skmLKB1-KO muscles after contraction. Using the downhill running model, we observed significantly more muscle damage after running in skmLKB1-KO mice, and this was associated with greater phosphorylation of both Jnk and STAT3 and increased expression of SOCS3 and Fos. In conclusion, we have shown that the lack of LKB1 in skeletal muscle leads to an increased inflammatory state in skeletal muscle that is exacerbated by muscle contraction. Increased susceptibility of the muscle to damage may underlie part of this response. Copyright © 2016 the American Physiological Society.

  19. Key Resources for Creating Online Nutrition Education for Those Participating in Supplemental Nutrition Assistance Program Education

    Science.gov (United States)

    Stosich, Marie C.; LeBlanc, Heidi; Kudin, Janette S.; Christofferson, Debra

    2016-01-01

    Internet-based nutrition education is becoming an important tool in serving the rural, low-income community, yet the task of creating such programming can be daunting. The authors describe the key resources used in developing an Internet-based nutrition education program for those participating in Supplemental Nutrition Assistance Program…

  20. Heuristic algorithm for single resource constrained project scheduling problem based on the dynamic programming

    Directory of Open Access Journals (Sweden)

    Stanimirović Ivan

    2009-01-01

    Full Text Available We introduce a heuristic method for the single resource constrained project scheduling problem, based on the dynamic programming solution of the knapsack problem. This method schedules projects with one type of resources, in the non-preemptive case: once started an activity is not interrupted and runs to completion. We compare the implementation of this method with well-known heuristic scheduling method, called Minimum Slack First (known also as Gray-Kidd algorithm, as well as with Microsoft Project.

  1. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program, fiscal year 1990

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Mark J.; Brooks, Richard D.; Sassaman, Kenneth E.; Crass, David C.; Lewis, George S.; Stephenson, D. Keith; Green, William; Anderson, David G.; Fuglseth, Ty

    1990-11-01

    The Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, is funded through a direct contract with the United States Department of Energy to provide services required under federal law for the protection and management of archaeological resources on the Savannah River Site (SRS). Because the significance of most archaeological resources is dependent upon research potential, the SRARP is guided by research objectives. An on-going research program provides the problems, methods and means of assessing site significance within the compliance process specified by law. In addition, the SRARP maintains an active program of public education to disseminate knowledge about prehistory and history, and to enhance public awareness about historic preservation. The following report summarizes the management, research and public education activities of the SRARP during Fiscal Year 1990.

  2. [Validation of the structure and resources of nosocomial infection control team in hospitals ascribed to VINCat program in Catalonia, Spain].

    Science.gov (United States)

    Limón, Enrique; Pujol, Miquel; Gudiol, Francesc

    2014-07-01

    The main objective of this study was to validate the structure of the infection control team (ICT) in the hospitals adhered to VINCat program and secondary objective was to establish the consistency of resources of each center with the requirements established by the program. Qualitative research consisting of an ethnographic study using participant observation during the years 2008-2010. The centers were stratified in three groups by complexity and beds. The instrument was a semistructured interview to members of the ICT. The transcription of the interview was sent to informants for validation. In November 2010 a questionnaire regarding human resources and number hours dedicated to the ICT was sent. During 2008-2010, 65 centers had been adhered to VINCat program. In 2010, the ICT of Group I hospitals had a mean of two physician, one in full-time and one nurse for every 230 beds. In Group II, one physician part-time and one nurse per 180 beds and in Group III a physician and a nurse for every 98 beds, both part-time. In 2010, all hospitals had a structured ICT, an operative infection committee, and a hospital member representing the center at the program as well as enough electronic resources. The hospitals participating in the program have now VINCat an adequate surveillance structure and meet the minimum technical and human resources required to provide high-quality data. However human resources are not guaranteed. Copyright © 2014. Published by Elsevier Espana.

  3. Worker programs and resource use: Evidence from better work jordan

    Science.gov (United States)

    Robins, Nathan

    This paper examines data collected for the Better Work program in Jordan which aims to protect laborers in the garment industry from poor working conditions. Data are examined to look for benefits to the factories participating in the program beyond improved compliance with labor law. In particular, potential impacts to firm energy use are examined and correlations are tested between electricity use rates and measures of worker outcomes and a number of factory traits such as size and production input costs. Evidence was found to back up work done in Vietnam with regard to resource use and distribution of electricity expenses. It was also found that the type of data being collected is not ideal for examinations of energy, and more direct methods are desirable, and that considerable production obstacles are worker skill level, electricity prices, and to a greater degree in Jordan than in previously examined countries, water prices.

  4. U.S. Geological Survey Mineral Resources Program—Mineral resource science supporting informed decisionmaking

    Science.gov (United States)

    Wilkins, Aleeza M.; Doebrich, Jeff L.

    2016-09-19

    The USGS Mineral Resources Program (MRP) delivers unbiased science and information to increase understanding of mineral resource potential, production, and consumption, and how mineral resources interact with the environment. The MRP is the Federal Government’s sole source for this mineral resource science and information. Program goals are to (1) increase understanding of mineral resource formation, (2) provide mineral resource inventories and assessments, (3) broaden knowledge of the effects of mineral resources on the environment and society, and (4) provide analysis on the availability and reliability of mineral supplies.

  5. Valuation of selected environmental impacts associated with Bonneville Power Administration Resource Program alternatives

    International Nuclear Information System (INIS)

    Englin, J.E.; Gygi, K.F.

    1992-03-01

    This report documents work undertaken by the Pacific Northwest Laboratory (PNL) and its contractors to assist the Bonneville Power Administration (Bonneville) in assessing the potential environmental consequences of new power resources. A major purpose of this effort is to describe and evaluate the techniques available for economic valuation of environmental costs. Another is to provide estimates of the environmental costs associated with specific power resources called for under Bonneville's Resource Programs. Bonneville's efforts to extend valuation techniques to as many impacts as can be reliably assessed represents a substantial advance in the application of state-of-the-art economic techniques to environmental assessments. This economic analysis evaluates effects on human health, wildlife, crops, and visibility impacts associated with air pollution. This report also discusses river recreation (primarily fishing) which may be affected by fluctuations in water levels. 70 refs

  6. Using analytical tools for decision-making and program planning in natural resources: breaking the fear barrier

    Science.gov (United States)

    David L. Peterson; Daniel L. Schmoldt

    1999-01-01

    The National Park Service and other public agencies are increasing their emphasis on inventory and monitoring (I&M) programs to obtain the information needed to infer changes in resource conditions and trigger management responses.A few individuals on a planning team can develop I&M programs, although a focused workshop is more effective.Workshops are...

  7. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program: Fiscal year 1991

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Mark J.; Brooks, Richard D.; Sassaman, Kenneth E.; Crass, David C.; Stephenson, D. Keith; Green, William; Rinehart, Charles J.; Lewis, George S.; Fuglseth, Ty; Krawczynski, Keith; Warnock, D. Mark

    1991-10-01

    A cooperative agreement with the United States Department of Energy provides the necessary funding for the Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, to render services required under federal law for the protection and management of archaeological resources on the Savannah River Site (SRS). Because the significance of archaeological resources is usually determined by research potential, the SRARP is guided by research objectives. An ongoing research program provides the theoretical, methodological and empirical basis for assessing site significance within the compliance process specified by law. In accordance with the spirit of the law, the SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research and public education activities of the SRARP during Fiscal Year 1991.

  8. The human resource management contribute six sigma program: multiple-case study in companies situated in Rio Grande do Sul

    Directory of Open Access Journals (Sweden)

    Jaqueline T. M. Corrêa Rodrigues

    2011-09-01

    Full Text Available The world is going through rapid changes and the companies seek alternatives to improve its products and processes and maintain their competitiveness. One alternative is the implementation of programs of quality management that combine human’s and technical’s factors. Six Sigma has gained evidence on the last years because aggregate tools and methodology. However, all quality program factors need management. The main goal of this paper is classify what assignments of Human Resource Management can contribute to reduction of the difficulties that can be encountered on implementation and maintenance of Six Sigma program in companies that was situated in the Rio Grande do Sul. For carry this work was necessary contact companies of the Rio Grande do Sul that use this program and was applied one questionnaire to classify the contribution of the Human Resource Management for the success of Six Sigma. The statistical tools, contents analyze, tables of relationship and qualitative analysis were applied for analysis. It’s evidence in this research the existence of potentials difficulties of Six Sigma listed in the literature and the influence that some assignments of Human Resource Management can be for solve this difficulties. The result of the research indicate that the participative and compromised leadership and the clear and objective communication of program are the assignments of Human Resource Management among the studied that more contribute for reduction of the difficulties of Six Sigma in the companies of this research.

  9. System of Budget Planning, Programming, Development and Execution and the Defence Resources Management Model (DRMM

    Directory of Open Access Journals (Sweden)

    Davor Čutić

    2010-07-01

    Full Text Available The system of budget planning, programming, development and execution of the Ministry of Defence of the Republic of Croatia (henceforth: the Croatian acronym SPPIIP is the basic system for the strategic management of defence resources through which an effective and rational distribution of available resources is conducted, based on the goals of national security of the Republic of Croatia. This system sets the principles of transparency and democratic management of defence resources while respecting the specificities of the defence system. The SPPIIP allows for decision making based on complete information about alternatives and the choice of the most economical and most efficient way to reach the goal. It unites the strategic plan, program and budget. It consists of four continuous, independent and interconnected phases: planning, programming, development and the execution of the budget. The processes of the phases are dynamic and cyclic. In addition to the SPPIIP, the Defence Resources Management Model (DRMM, Croatian acronym: MURO has also been developed. This is an analytic tool which serves as a decision support system in the SPPIIP. The DRMM is a complex computer model showing graph and tabular overviews in a multi-year period. The model examines three areas: the strength of the forces, expenses and defence programs. The purpose of the model is cost and strength analysis and the analysis of compromise and feasibility, i.e. how sensitive the programs are to fiscal movements in the sphere of the MoD budget in the course of a multiyear cycle, until a certain project ends. The analysis results are an easily understandable basis for decision making. The SPPIIP and the DRMM are mutually independent systems, but they complement each other well. The SPPIIP uses the DRMM in designing and resource allocation based on the goals set. The quality of the DRMM depends on the amount and quality of data in its database. The DRMM can be used as a basis for

  10. Technical procedures for water resources: Volume 3, Environmental Field Program, Deaf Smith County Site, Texas: Final draft

    International Nuclear Information System (INIS)

    1987-08-01

    To ensure that the environmental field program comprehensively addresses the issues and requirements of the project, a site study plan (SSP) has been prepared for Water Resources (ONWI, 1987). This technical procedure (TP) has been developed to implement the field program described in the Water Resources Site Study Plan. This procedure provides the general method for the field collection of water and sediment samples from playa lakes using an Alpha horizontal type sampler or equivalent or a peristaltic pump for water and a KB-coring devise or ponar grab for sediments. The samples will be preserved and then shipped to a laboratory for analysis. The water quality and sediment samples will be collected as part of the surface-water quality field study described in the Site Plan for Water Resources. 15 refs., 5 figs., 3 tabs

  11. Initial Analyses of Change Detection Capabilities and Data Redundancies in the Long Term Resource Monitoring Program

    National Research Council Canada - National Science Library

    Lubinski, Kenneth

    2001-01-01

    Evaluations of Long Term Resource Monitoring Program sampling designs for water quality, fish, aquatic vegetation, and macroinvertebrates were initiated in 1999 by analyzing data collected since 1992...

  12. 78 FR 23290 - Renewal of Agency Information Collection for Energy Resource Development Program Grants

    Science.gov (United States)

    2013-04-18

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs [DR.5B813.IA001113] Renewal of Agency Information Collection for Energy Resource Development Program Grants AGENCY: Bureau of Indian Affairs... 1995, the Assistant Secretary--Indian Affairs is seeking comments on the renewal of Office of...

  13. 78 FR 4867 - Renewal of Agency Information Collection for Energy Resource Development Program Grants

    Science.gov (United States)

    2013-01-23

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Renewal of Agency Information Collection for Energy Resource Development Program Grants AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of... Secretary--Indian Affairs is seeking comments on the renewal of Office of Management and Budget (OMB...

  14. Nutrition Education Resources in North Carolina-Based Head Start Preschool Programs: Administrator and Teacher Perceptions of Availability and Use.

    Science.gov (United States)

    Lisson, Sarah; Goodell, L Suzanne; Dev, Dipti; Wilkerson, Kristi; Hegde, Archana V; Stage, Virginia C

    2016-10-01

    The purpose of this study was to provide new insight into common barriers to the availability and use of nutrition education (NE) resources in Head Start preschool programs based on administrator and teacher perceptions. In-depth, semistructured phone interviews (n = 63) were conducted with administrators (n = 31) and teachers (n = 32) from North Carolina-based Head Start programs. Interviews were audio-recorded and transcribed verbatim. Data were analyzed qualitatively using content analysis to identify common themes. Five emergent themes were identified within the areas of NE resource availability and use and barriers to NE resource availability and use. Participants expressed desire for greater organization of existing NE material resources, increased community support, and professional development opportunities for teachers specific to NE. Funding and time constraints were reported as affecting NE resources. Creative strategies for addressing NE resource availability and use and barriers (eg, NE integration with educational standards) in Head Start are needed. Copyright © 2016 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  15. Hydrologic Resources Management Program and Underground Test Area Project FY2005 Progress Report

    International Nuclear Information System (INIS)

    Eaton, G F; Genetti, V; Hu, Q; Hudson, G B; Kersting, A B; Lindvall, R E; Moran, J E; Nimz, G J; Ramon, E C; Rose, T P; Shuller, L; Williams, R W; Zavarin, M; Zhao, P

    2007-01-01

    This report describes FY 2005 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area Project (UGTA). These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The report is organized on a topical basis and contains five chapters that highlight technical work products produced by CBND. However, it is important to recognize that most of this work involves collaborative partnerships with the other HRMP and UGTA contract organizations. These groups include the Energy and Environment Directorate at LLNL (LLNL-E and E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and Bechtel Nevada (BN)

  16. Reentry Orientation and Alumni Networking in U.S. Colleges and Universities with Agriculture and Natural Resources Programs. Survey Report.

    Science.gov (United States)

    Huntsberger, Paul E.

    This report presents results of a survey of U.S. postsecondary institutions with agriculture and natural resources programs, concerning institutional support for reentry orientation and alumni networking programs. Reentry orientation" involves programs that help international students become aware of the adjustment aspects of returning home,…

  17. Introducing priority setting and resource allocation in home and community care programs.

    Science.gov (United States)

    Urquhart, Bonnie; Mitton, Craig; Peacock, Stuart

    2008-01-01

    To use evidence from research to identify and implement priority setting and resource allocation that incorporates both ethical practices and economic principles. Program budgeting and marginal analysis (PBMA) is based on two key economic principles: opportunity cost (i.e. doing one thing instead of another) and the margin (i.e. resource allocation should result in maximum benefit for available resources). An ethical framework for priority setting and resource allocation known as Accountability for Reasonableness (A4R) focuses on making sure that resource allocations are based on a fair decision-making process. It includes the following four conditions: publicity; relevance; appeals; and enforcement. More recent literature on the topic suggests that a fifth condition, that of empowerment, should be added to the Framework. The 2007-08 operating budget for Home and Community Care, excluding the residential sector, was developed using PBMA and incorporating the A4R conditions. Recommendations developed using PBMA were forwarded to the Executive Committee, approved and implemented for the 2007-08 fiscal year operating budget. In addition there were two projects approved for approximately $200,000. PBMA is an improvement over previous practice. Managers of Home and Community Care are committed to using the process for the 2008-09 fiscal year operating budget and expanding its use to include mental health and addictions services. In addition, managers of public health prevention and promotion services are considering using the process.

  18. Development of a Virtual Crew Resource Management Training Program to Improve Communication.

    Science.gov (United States)

    Tschannen, Dana

    2017-11-01

    Crew Resource Management (CRM), a method focused on the management of human error and risk reduction, has shown promise in reducing communication failure in health care. The purpose of this project was to develop a virtual training program in CRM principles of effective leadership and followership, and evaluate the applicability to nurses working in the hospital setting. The intervention included the development of a virtual CRM training program consisting of a self-learning module and virtual simulation. Beta testing of the module was conducted by six nurses, followed by an evaluation of the training program by nurses (n = 5) in a general medicine department. Nurses reported the overall program to be worthwhile (X̄= 5; SD = 0.5), with great applicability to nursing care (X̄= 4.5, SD = 0.5). Nurses completing the simulation activity reported strong agreement to CRM applicability and training effectiveness. The CRM training module proved to be applicable to nursing care and is ready for widespread use to improve patient care and communication. J Contin Educ Nurs. 2017;48(11):525-532. Copyright 2017, SLACK Incorporated.

  19. The scope of the Weatherization Assistance Program: The weatherized population and the resource base

    Energy Technology Data Exchange (ETDEWEB)

    Power, M.; Eisenberg, J.F.; Michels, E. (Economic Opportunity Research Inst., Washington, DC (United States)); Witherspoon, M.J. (National Association for State Community Service Programs, Washington, DC (United States)); Brown, M.A. (Oak Ridge National Lab., TN (United States))

    1992-05-01

    This study is one of five parts of the US Department of Energy's national evaluation of its Weatherization Assistance Program (WAP). It has three major goals: (1) to enumerate the size and sources of investment in low-income weatherization; (2) to provide a count of the number of low-income units weatherized by all weatherization programs and characterized the type and tenure of those homes; and (3) to document the extent to which the DOE/WAP funding has been expanded though use of external resources.

  20. The scope of the Weatherization Assistance Program: The weatherized population and the resource base

    Energy Technology Data Exchange (ETDEWEB)

    Power, M.; Eisenberg, J.F.; Michels, E. [Economic Opportunity Research Inst., Washington, DC (United States); Witherspoon, M.J. [National Association for State Community Service Programs, Washington, DC (United States); Brown, M.A. [Oak Ridge National Lab., TN (United States)

    1992-05-01

    This study is one of five parts of the US Department of Energy`s national evaluation of its Weatherization Assistance Program (WAP). It has three major goals: (1) to enumerate the size and sources of investment in low-income weatherization; (2) to provide a count of the number of low-income units weatherized by all weatherization programs and characterized the type and tenure of those homes; and (3) to document the extent to which the DOE/WAP funding has been expanded though use of external resources.

  1. The Next Step in Educational Program Budgets and Information Resource Management: Integrated Data Structures.

    Science.gov (United States)

    Jackowski, Edward M.

    1988-01-01

    Discusses the role that information resource management (IRM) plays in educational program-oriented budgeting (POB), and presents a theoretical IRM model. Highlights include design considerations for integrated data systems; database management systems (DBMS); and how POB data can be integrated to enhance its value and use within an educational…

  2. The Glen Canyon Dam Adaptive Management Program: An experiment in science-based resource management

    Science.gov (United States)

    kaplinski, m

    2001-12-01

    In 1996, Glen Canyon Dam Adaptive Management (GCDAMP) program was established to provide input on Glen Canyon Dam operations and their affect on the Colorado Ecosystem in Grand Canyon. The GCDAMP is a bold experiment in federal resource management that features a governing partnership with all relevant stakeholders sitting at the same table. It is a complicated, difficult process where stakeholder-derived management actions must balance resource protection with water and power delivery compacts, the Endangered Species Act, the National Historical Preservation Act, the Grand Canyon Protection Act, National Park Service Policy, and other stakeholder concerns. The program consists of four entities: the Adaptive Management Workgroup (AMWG), the Technical Workgroup (TWG), the Grand Canyon Monitoring and Research Center (GCMRC), and independent review panels. The AMWG and TWG are federal advisory committees that consists of federal and state resource managers, Native American tribes, power, environmental and recreation interests. The AMWG is develops, evaluates and recommends alternative dam operations to the Secretary. The TWG translates AMWG policy and goals into management objectives and information needs, provides questions that serve as the basis for long-term monitoring and research activities, interprets research results from the GCMRC, and prepares reports as required for the AMWG. The GCMRC is an independent science center that is responsible for all GCDAMP monitoring and research activities. The GCMRC utilizes proposal requests with external peer review and an in-house staff that directs and synthesizes monitoring and research results. The GCMRC meets regularly with the TWG and AMWG and provides scientific information on the consequences of GCDAMP actions. Independent review panels consist of external peer review panels that provide reviews of scientific activities and the program in general, technical advice to the GCMRC, TWG and AMWG, and play a critical

  3. Progress report Waste Resources Utilization Program period ending March 31, 1976

    International Nuclear Information System (INIS)

    1976-06-01

    This report describes the work on the Waste Resources Utilization Program for the quarter ending March 31, 1976. The purpose of this program is to develop technologies to utilize a 137 Cs γ source to modify sewage sludge for safe application as a fertilizer or an animal feed supplement. Results are reported from studies in microbiology, virology, and physical-chemical studies. Determinations were made of inactivation rates for Salmonella species, coliforms, and fecal strep in sewage sludge when radiation and thermoradiation were applied while bubbling oxygen through the sludge. Virology studies were continued investigating virucidal characteristics of anaerobically digested sludge. Another area of study was the dewatering of sewage sludge to reduce the drying time of the sewage sludge in the drying beds. A centrifuge was also installed to dewater treated sludge to approximately 30 percent solids

  4. Hydrogeochemical and stream sediment reconnaissance (HSSR) program of the National Uranium Resource Evaluation (NURE) 1973-1984. Technical history

    International Nuclear Information System (INIS)

    1985-01-01

    The Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) program of the National Uranium Resource Evaluation (NURE) generated a database of interest to scientists and other professional personnel in the academic, business, industrial, and governmental communities. NURE was a program of the Department of Energy Grand Junction Office (GJO) to acquire and compile geologic and other information with which to assess the magnitude and distribution of uranium resources and to determine areas favorable for the occurrence of uranium in the United States. The HSSR program provided for the collection of water and sediment samples located on the 1 0 x 2 0 National Topographic Map Series (NTMS) quadrangle grid across the conterminous United States and Alaska and the analysis of these samples for uranium as well as for a number of additional elements. Although the initial purpose of the program was to provide information regarding uranium resources, the information recorded about other elements and general field or site characteristics has made this database potentially valuable for describing the geochemistry of a location and addressing other issues such as water quality. The purpose of this Technical History is to summarize in one report those aspects of the HSSR program that are likely to be important in helping users assess the database and make informed judgements about its application to specific research questions. The history begins with an overview of the NURE Program and its components. Following a general description of the goals, objectives, and key features of the HSSR program, the implementation of the program at each of the four federal laboratories is presented in four separate chapters. These typically cover such topics as sample collection, sample analysis, and data management. 80 refs., 5 figs., 9 tabs

  5. Field manual for ground water reconnaissance. Savannah River Laboratory National Uranium Resource Evaluation Program

    International Nuclear Information System (INIS)

    Ferguson, R.B.; Price, V.; Baucom, E.I.

    1977-01-01

    A manual is presented that is intended to direct and coordinate field operations, site selection, groundwater sample collection, and information codes for the Savannah River Laboratory (SRL) contribution to the National Uranium Resource Evaluation (NURE) program. The manual provides public relations information for field sampling teams as well as technical direction

  6. Design and Implementation of a Pilot Obesity Prevention Program in a Low-Resource School: Lessons Learned and Research Recommendations

    Science.gov (United States)

    Baskin, Monica L.; Zunker, Christie; Worley, Courtney B.; Dial, Brenda; Kimbrough, Linda

    2009-01-01

    Purpose: This paper seeks to describe the design, implementation, and lessons learned from an obesity prevention pilot program delivered in a low resource school in the USA. Design/methodology/approach: A planned program evaluation was conducted to: document explicitly the process of designing and implementing the program; and assess the…

  7. Application of Kriging to hydrogeochemical data from the National Uranium Resource Evaluation Program

    International Nuclear Information System (INIS)

    Myers, D.E.; Begovich, C.L.; Butz, T.R.; Kane, V.E.

    1980-12-01

    The Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) Program is an important part of the data collection segment of the NURE Program. This report presents the preliminary results of applying a new geostatistical tool, known as Kriging, to HSSR data from the Plainview Quadrangle in Texas. The essential conclusion of this report is that Kriging can be useful in characterizing geochemical data and identification of the anomalous geographic regions used in resource appraisal. Computer codes were prepared for use either on other variables or stream sediment data and/or data from other quadrangles. Several ways of using Kriging to enhance HSSR data for the purpose of identifying favorable areas were identified

  8. Identifying state resources and support programs on e-government websites for persons with intellectual and developmental disabilities.

    Science.gov (United States)

    Fisher, Kathleen M; Peterson, Justin D; Albert, Jon D

    2015-01-01

    This descriptive cross-sectional study identified resources and programs that are available nationwide on the Internet to support individuals and families with intellectual and developmental disabilities (I/DD), with a focus on intellectual disability. This evaluation included easily identifiable information on specific resources and highlighted unique programs found in individual states that were linked from e-government websites. Researchers documented the ease of access and available information for all 50 states and the District of Columbia. A number of disparities and areas for improvement were recorded for states and I/DD websites. The researchers conclude that a number of additional health and support services will be needed to address the growing needs of this vulnerable population.

  9. Multiyear Synthesis of Limnological Data from 1993 to 2001 for the Long Term Resource Monitoring Program

    National Research Council Canada - National Science Library

    Houser, Jeffrey N; Bierman, David W; Burdis, Robert M; Fischer, James R; Rogala, James T; Soeken-Gittinger, Lori A; Hoff, Kraig L; Harms, Erik

    2005-01-01

    .... The Long Term Resource Monitoring Program (LTRMP) provides a systemic perspective through the collection and analysis of monitoring data from six study reaches representing the upper, lower, and open river reaches of the UMRS...

  10. Geology and mineral resources of the Florence, Beaufort, Rocky Mount, and Norfolk 1/sup 0/ x 2/sup 0/ NTMS quadrangles. National Uranium Resource Evaluation program

    Energy Technology Data Exchange (ETDEWEB)

    Harris, W.B.

    1982-08-01

    This document provides geologic and mineral resources data for previously-issued Savannah River Laboratory hydrogeochemical and stream sediment reports of the Beaufort, Florence, Norfolk, and Rocky Mount 1/sup 0/ x 2/sup 0/ National Topographic Map Series quadrangles in the southeastern United States. This report is issued in draft form, without detailed technical and copy editing. This was done to make the report available to the public before the end of the National Uranium Resource Evaluation program.

  11. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    The Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, manages archaeological resources on the Savannah River Site (SRS). An ongoing research program provides the theoretical, methodological, and empirical basis for assessing site significance within the compliance process specified by law. The SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research, and public education activities of the SRARP during Fiscal Year 1994.

  12. Field manual for stream sediment reconnaissance. Savannah River Laboratory National Uranium Resource Evaluation Program

    International Nuclear Information System (INIS)

    Ferguson, R.B.; Price, V.; Baucom, E.I.

    1976-07-01

    A manual is presented that is intended to direct and coordinate field operations, site selection, stream sediment sample collection, water sample collection, and information codes for the Savannah River Laboratory (SRL) contribution to the National Uranium Resource Evaluation (NURE) program. The manual provides public relations information for field sampling teams as well as technical direction

  13. An analysis of factors affecting participation behavior of limited resource farmers in agricultural cost-share programs in Alabama

    Science.gov (United States)

    Okwudili Onianwa; Gerald Wheelock; Buddhi Gyawali; Jianbang Gan; Mark Dubois; John Schelhas

    2004-01-01

    This study examines factors that affect the participation behavior of limited resource farmers in agricultural cost-share programs in Alabama. The data were generated from a survey administered to a sample of limited resource farm operators. A binary logit model was employed to analyze the data. Results indicate that college education, age, gross sales, ratio of owned...

  14. Using Stochastic Dynamic Programming to Support Water Resources Management in the Ziya River Basin, China

    DEFF Research Database (Denmark)

    Davidsen, Claus; Cardenal, Silvio Javier Pereira; Liu, Suxia

    2015-01-01

    of stochastic dynamic programming, to optimize water resources management in the Ziya River basin. Natural runoff from the upper basin was estimated with a rainfall-runoff model autocalibrated using in situ measured discharge. The runoff serial correlation was described by a Markov chain and used as input...

  15. 1994 Annual wildlife survey report. Natural Resource Protection and Compliance Program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-24

    This report summarizes the results of wildlife surveys and other wildlife monitoring performed from January through December 1994. These surveys are part of a long-term ecological monitoring program conducted under the Natural Resource Protection and Compliance Program (NRPCP). This program is essential in identifying and quantifying fluctuations of wildlife populations, wildlife habitat use, and changes in the species using the Rocky Flats Environmental Technology Site (Site) as year-round or seasonal habitat. Wildlife population densities vary constantly due to natural pressures, and only well-integrated, long-term monitoring can identify which factors influencing wildlife populations are a consequence of natural causes, and which are due to human activities. An integrated monitoring program that gathers data on ecologically interactive species is essential in evaluating population fluctuations. Such data can be an invaluable tool in predicting and avoiding impacts on the ecology of an area due to projected human activities. With 167 species of birds, three big game species, nine species of carnivores, nine species of mid-sized mammals, and 15 small mammal species, the Site provides habitat to a surprising variety of wildlife. Many of these species are sensitive species or indicator organisms that by their presence or, more significantly, by their absence can indicate the ecological health of an area. Their presence at the Site indicates a very healthy ecosystem.

  16. Resource conservation management

    International Nuclear Information System (INIS)

    Miller, W.

    1999-01-01

    Resource conservation management is a management program similar to financial management in that its success requires commitment by all levels of the organization to the process as well as an accounting procedure and auditing of critical components. Resource conservation management provides a framework for all elements of efficient building operations and maintenance. The savings connected with the program are principally connected with changes in the way buildings are operated and maintained. Given the reduction in rebates for the installation of energy-efficient equipment, this approach has considerable promise. This paper discusses the evolution of the resource conservation management service and the savings associated with a two-year pilot effort with seven school districts, as well as the critical components of a successful program

  17. The Effectiveness of Empowerment Program on Increasing Self-Esteem, Learned Resourcefulness, and Coping Ways in Women Exposed to Domestic Violence.

    Science.gov (United States)

    Bahadir-Yilmaz, Emel; Öz, Fatma

    2018-02-01

    This study was conducted to assess the effectiveness of empowerment program on increasing self-esteem, learned resourcefulness, and coping ways in women exposed to domestic violence. This experimental study was conducted between October 2012 and June 2014 in the obstetrics and gynaecology departments of the Giresun Maternity Hospital, and at the Family Counseling Center (FCC) in Turkey. Sixty women who agreed to participate in the study were randomly assigned into two groups. Data were collected by the Coopersmith Self-Esteem Inventory (SEI), The Rosenbaum's Learned Resourcefulness Scale (RLRS), and the Ways of Coping Inventory (WCI). The assessment of the women before and after the empowerment program showed that women in the intervention group showed significant improvements in the SEI, RLRS, and WCI scores compared with controls. These results suggest that the empowerment program is an effective practice for increasing the levels of self-esteem, learned resourcefulness, and coping ways of women exposed to domestic violence.

  18. Final Report Low-temperature Resource Assessment Program

    Energy Technology Data Exchange (ETDEWEB)

    Lienau, P.J. [Geo-Heat Center, Oregon Institute of Technology, Klamath Falls, OR (US); Ross, H. [Earth Sciences and Resources Institute, University of Utah

    1996-02-01

    The U.S. Department of Energy - Geothermal Division (DOE/GD) recently sponsored the Low-Temperature Resource Assessment project to update the inventory of the nation's low- and moderate-temperature geothermal resources and to encourage development of these resources. A database of 8,977 thermal wells and springs that are in the temperature range of 20 degrees Celsius to 150 degrees Celsius has been compiled for ten western states, an impressive increase of 82% compared to the previous assessments. The database includes location, descriptive data, physical parameters, water chemistry and references for sources of data. Computer-generated maps are also available for each state. State Teams have identified 48 high-priority areas for near-term comprehensive resource studies and development. Resources with temperatures greater than 50 degrees Celsius located within 8 km of a population center were identified for 271 collocated cities. Geothermal energy costevaluation software has been developed to quickly identify the cost of geothermally supplied heat to these areas in a fashion similar to that used for conventionally fueled heat sources.

  19. Directory of Academic Institutions and Organizations Offering Drug, Alcohol, and Employee Assistance Program Educational Resources.

    Science.gov (United States)

    National Inst. on Drug Abuse (DHHS/PHS), Rockville, MD.

    This directory lists academic institutions, State offices of alcohol and drug abuse, and national organizations which offer drug, alcohol, and employee assistance program (EAP) educational resources. A matrix format is used. Entries include name, address, telephone number, and contact person. A dot appears directly under column headings which are…

  20. The Electron Microscopy Outreach Program: A Web-based resource for research and education.

    Science.gov (United States)

    Sosinsky, G E; Baker, T S; Hand, G; Ellisman, M H

    1999-01-01

    We have developed a centralized World Wide Web (WWW)-based environment that serves as a resource of software tools and expertise for biological electron microscopy. A major focus is molecular electron microscopy, but the site also includes information and links on structural biology at all levels of resolution. This site serves to help integrate or link structural biology techniques in accordance with user needs. The WWW site, called the Electron Microscopy (EM) Outreach Program (URL: http://emoutreach.sdsc.edu), provides scientists with computational and educational tools for their research and edification. In particular, we have set up a centralized resource containing course notes, references, and links to image analysis and three-dimensional reconstruction software for investigators wanting to learn about EM techniques either within or outside of their fields of expertise. Copyright 1999 Academic Press.

  1. Evaluating Behaviorally Oriented Aviation Maintenance Resource Management (MRM) Training and Programs: Methods, Results, and Conclusions

    Science.gov (United States)

    Taylor, James C.; Thomas, Robert L., III

    2003-01-01

    Assessment of the impact of Aviation Resource Management Programs on aviation culture and performance has compelled a considerable body of research (Taylor & Robertson, 1995; Taylor, 1998; Taylor & Patankar, 2001). In recent years new methods have been applied to the problem of maintenance error precipitated by factors such as the need for self-assessment of communication and trust. The present study - 2002 -- is an extension of that past work. This research project was designed as the conclusion of a larger effort to help understand, evaluate and validate the impact of Maintenance Resource Management (MRM) training programs, and other MRM interventions on participant attitudes, opinions, behaviors, and ultimately on enhanced safety performance. It includes research and development of evaluation methodology as well as examination of psychological constructs and correlates of maintainer performance. In particular, during 2002, three issues were addressed. First, the evaluation of two (independent & different) MRM programs for changing behaviors was undertaken. In one case we were able to further apply the approach to measuring written communication developed during 2001 (Taylor, 2002; Taylor & Thomas, 2003). Second, the MRM/TOQ surveys were made available for completion on the internet. The responses from these on-line surveys were automatically linked to a results calculator (like the one developed and described in Taylor, 2002) to aid industry users in analyzing and evaluating their local survey data on the internet. Third, the main trends and themes from our research about MRM programs over the past dozen years were reviewed.

  2. The Natural Resources Conservation Service land resource hierarchy and ecological sites

    Science.gov (United States)

    Resource areas of the NRCS have long been important to soil geography. At both regional and landscape scales, resource areas are used to stratify programs and practices based on geographical areas where resource concerns, problems, or treatment needs are similar. However, the inability to quantifiab...

  3. Technologies for Distributed Energy Resources. Federal Energy Management Program (FEMP) Technical Assistance Fact Sheet

    International Nuclear Information System (INIS)

    Pitchford, P.; Brown, T.

    2001-01-01

    This four-page fact sheet describes distributed energy resources for Federal facilities, which are being supported by the U.S. Department of Energy's (DOE's) Federal Energy Management Program (FEMP). Distributed energy resources include both existing and emerging energy technologies: advanced industrial turbines and microturbines; combined heat and power (CHP) systems; fuel cells; geothermal systems; natural gas reciprocating engines; photovoltaics and other solar systems; wind turbines; small, modular biopower; energy storage systems; and hybrid systems. DOE FEMP is investigating ways to use these alternative energy systems in government facilities to meet greater demand, to increase the reliability of the power-generation system, and to reduce the greenhouse gases associated with burning fossil fuels

  4. Optimising the extraction rate of a non-durable non-renewable resource in a monopolistic market: a mathematical programming approach.

    Science.gov (United States)

    Corominas, Albert; Fossas, Enric

    2015-01-01

    We assume a monopolistic market for a non-durable non-renewable resource such as crude oil, phosphates or fossil water. Stating the problem of obtaining optimal policies on extraction and pricing of the resource as a non-linear program allows general conclusions to be drawn under diverse assumptions about the demand curve, discount rates and length of the planning horizon. We compare the results with some common beliefs about the pace of exhaustion of this kind of resources.

  5. Open Educational Resources: A Review of Attributes for Adoption in an Online Bachelor's Degree Program

    Science.gov (United States)

    Neely, Patricia; Tucker, Jan P.; Au, Angela

    2016-01-01

    As concerns about the skyrocketing costs of a college degree have converged with the increasing availability of open educational resources (OER), higher education administrators are asking faculty and curriculum designers to use OERs to design courses and programs. This case study explores the decision making process and outcomes of an online,…

  6. Hydrologic resources management program, FY 1998 progress report; FINAL

    International Nuclear Information System (INIS)

    Benedict, F.C.; Criss, R.E.; Davisson, M.L.; Eaton, G.F.; Hudson, G.B.; Kenneally, J.M.; Rose, T.P.; Smith, D.

    1999-01-01

    This report presents the results from FY 1998 technical studies conducted by Lawrence Livermore National Laboratory (LLNL) as part of the Hydrology and Radionuclide Migration Program (HRMP) and Underground Test Area (UGTA) project. The HRMP is sponsored by Defense Programs (DP) of the U.S. Department of Energy, Nevada Operations Office (DOE/NV), and supports DP operations at the Nevada Test Site (NTS) through studies of radiochemistry and resource management related to the defense programs mission. Other participating organizations include the Los Alamos National Laboratory (LANL), the United States Geological Survey (USGS), the Desert Research Institute (DRI) of the University of Nevada, the United States Environmental Protection Agency (EPA), and Bechtel-Nevada (BN). The UGTA project is an Environmental Management (EM) activity of DOE/NV that supports a Federal Facilities Agreement and Consent Order between the Department of Energy, the Department of Defense, and the State of Nevada. UGTA's primary function is to address the legacy release of hazardous constituents at the Nevada Test Site, the Tonopah Test Range, and off-Nevada Test Site underground nuclear testing areas. Participating contractors include LLNL (Earth and Environmental Sciences Directorate, Analytical and Nuclear Chemistry Division), LANL, DRI, USGS, BN, HSI-GeoTrans, and IT Corporation. The FY 1998 HRMP and UGTA annual progress report follows the organization and contents of our FY 1997 report (Smith et al., 1998), and includes our results from CY 1997-1998 technical studies of radionuclide migration and isotope hydrology at the Nevada Test Site. During FY 1998, LLNL continued its efforts under the HRMP to pursue a technical agenda relevant to the science-based stockpile stewardship program at DOE/NV. Support to UGTA in FY 1998 included efforts to quantitatively define the radionuclide source term residual from underground nuclear weapons testing and the derivative solution, or hydrologic source

  7. Energy management in microgrid based on the multi objective stochastic programming incorporating portable renewable energy resource as demand response option

    International Nuclear Information System (INIS)

    Tabar, Vahid Sohrabi; Jirdehi, Mehdi Ahmadi; Hemmati, Reza

    2017-01-01

    Renewable energy resources are often known as cost-effective and lucrative resources and have been widely developed due to environmental-economic issues. Renewable energy utilization even in small scale (e.g., microgrid networks) has attracted significant attention. Energy management in microgrid can be carried out based on the generating side management or demand side management. In this paper, portable renewable energy resource are modeled and included in microgrid energy management as a demand response option. Utilizing such resources could supply the load when microgrid cannot serve the demand. This paper addresses energy management and scheduling in microgrid including thermal and electrical loads, renewable energy sources (solar and wind), CHP, conventional energy sources (boiler and micro turbine), energy storage systems (thermal and electrical ones), and portable renewable energy resource (PRER). Operational cost of microgrid and air pollution are considered as objective functions. Uncertainties related to the parameters are incorporated to make a stochastic programming. The proposed problem is expressed as a constrained, multi-objective, linear, and mixed-integer programing. Augmented Epsilon-constraint method is used to solve the problem. Final results and calculations are achieved using GAMS24.1.3/CPLEX12.5.1. Simulation results demonstrate the viability and effectiveness of the proposed method in microgrid energy management. - Highlights: • Introducing portable renewable energy resource (PRER) and considering effect of them. • Considering reserve margin and sensitivity analysis for validate robustness. • Multi objective and stochastic management with considering various loads and sources. • Using augmented Epsilon-constraint method to solve multi objective program. • Highly decreasing total cost and pollution with PRER in stochastic state.

  8. Hydrography - Water Resources

    Data.gov (United States)

    NSGIC Education | GIS Inventory — A Water Resource is a DEP primary facility type related to the Water Use Planning Program. The sub-facility types related to Water Resources that are included are:...

  9. Multimedia messages in genetics: design, development, and evaluation of a computer-based instructional resource for secondary school students in a Tay Sachs disease carrier screening program.

    Science.gov (United States)

    Gason, Alexandra A; Aitken, MaryAnne; Delatycki, Martin B; Sheffield, Edith; Metcalfe, Sylvia A

    2004-01-01

    Tay Sachs disease is a recessively inherited neurodegenerative disorder, for which carrier screening programs exist worldwide. Education for those offered a screening test is essential in facilitating informed decision-making. In Melbourne, Australia, we have designed, developed, and evaluated a computer-based instructional resource for use in the Tay Sachs disease carrier screening program for secondary school students attending Jewish schools. The resource entitled "Genetics in the Community: Tay Sachs disease" was designed on a platform of educational learning theory. The development of the resource included formative evaluation using qualitative data analysis supported by descriptive quantitative data. The final resource was evaluated within the screening program and compared with the standard oral presentation using a questionnaire. Knowledge outcomes were measured both before and after either of the educational formats. Data from the formative evaluation were used to refine the content and functionality of the final resource. The questionnaire evaluation of 302 students over two years showed the multimedia resource to be equally effective as an oral educational presentation in facilitating participants' knowledge construction. The resource offers a large number of potential benefits, which are not limited to the Tay Sachs disease carrier screening program setting, such as delivery of a consistent educational message, short delivery time, and minimum financial and resource commitment. This article outlines the value of considering educational theory and describes the process of multimedia development providing a framework that may be of value when designing genetics multimedia resources in general.

  10. State Electricity Regulatory Policy and Distributed Resources: Distributed Resources and Electric System Reliability

    Energy Technology Data Exchange (ETDEWEB)

    Cowart, R.; Harrington, C.; Moskovitz, D.; Shirley, W.; Weston, F.; Sedano, R.

    2002-10-01

    Designing and implementing credit-based pilot programs for distributed resources distribution is a low-cost, low-risk opportunity to find out how these resources can help defer or avoid costly electric power system (utility grid) distribution upgrades. This report describes implementation options for deaveraged distribution credits and distributed resource development zones. Developing workable programs implementing these policies can dramatically increase the deployment of distributed resources in ways that benefit distributed resource vendors, users, and distribution utilities. This report is one in the State Electricity Regulatory Policy and Distributed Resources series developed under contract to NREL (see Annual Technical Status Report of the Regulatory Assistance Project: September 2000-September 2001, NREL/SR-560-32733). Other titles in this series are: (1) Accommodating Distributed Resources in Wholesale Markets, NREL/SR-560-32497; (2) Distributed Resources and Electric System Re liability, NREL/SR-560-32498; (3) Distribution System Cost Methodologies for Distributed Generation, NREL/SR-560-32500; (4) Distribution System Cost Methodologies for Distributed Generation Appendices, NREL/SR-560-32501.

  11. Lightning Safety Tips and Resources

    Science.gov (United States)

    ... Services Careers Contact Us Glossary Safety National Program Lightning Safety Tips and Resources Weather.gov > Safety > Lightning Safety Tips and Resources Lightning Resources Lightning strikes ...

  12. NWS Water Resource Services Branch Division

    Science.gov (United States)

    the NWS homepage NWS Water Resources Program OS Home News Organization Search Search Home About Us Water Resources Policy Flood Loss Data AHPS Program Office (OHD) AHPS Software Development Hydrology Lab AHPS Toolbox Flood Safety Service Hydrology Program Turn Around Don't Drown! High Water Mark Signs

  13. Recruitment of Older Adult Patient-Caregiver Dyads for an Online Caregiver Resource Program: Lessons Learned.

    Science.gov (United States)

    Nahm, Eun-Shim; Orwig, Denise; Resnick, Barbara; Magaziner, Jay; Bellantoni, Michele; Sterling, Robert

    2012-01-12

    Hip fracture is a significant health problem for older adults and generally requires surgery followed by intensive rehabilitation. Informal caregivers (CGs) can provide vital assistance to older adults recovering from hip fracture. Caregiving is a dyadic process that affects both CGs and care recipients (CRs). In a feasibility study, we assessed the effects of using a theory-based online hip fracture resource program for CGs on both CGs and CRs. In this article, we discuss our recruitment process and the lessons learned. Participants were recruited from six acute hospitals, and CGs used the online resource program for 8 weeks. A total of 256 hip fracture patients were screened, and 164 CRs were ineligible. CG screening was initiated when CRs were determined to be eligible. Among 41 eligible dyads, 36 dyads were recruited. Several challenges to the recruitment of these dyads for online studies were identified, including a low number of eligible dyads in certain hospitals and difficulty recruiting both the CR and the CG during the short hospital stay. Field nurses often had to make multiple trips to the hospital to meet with both the CR and the CG. Thus, when a subject unit is a dyad recruited from acute settings, the resources required for the recruitment may be more than doubled. These challenges could be successfully alleviated with careful planning, competent field staff members, collaboration with hospital staff members, and efficient field operations.

  14. The effects of a childbirth psychoeducation program on learned resourcefulness, maternal role competence and perinatal depression: a quasi-experiment.

    Science.gov (United States)

    Ngai, Fei-Wan; Chan, Sally Wai-Chi; Ip, Wan-Yim

    2009-10-01

    Learned resourcefulness plays a significant role in facilitating maternal coping during the transition to motherhood. Given the growing evidence of perinatal depression and the frequent feeling of incompetence in the maternal role, the implementation of an effective intervention to promote maternal role competence and emotional well-being is essential. To determine the impact of a childbirth psychoeducation program based on the concept of learned resourcefulness on maternal role competence and depressive symptoms in Chinese childbearing women. A pretest-posttest, control group quasi-experimental design with repeated measures was used. The study was conducted in two regional public hospitals in Hong Kong that provide routine childbirth education programs with similar content and structure. One hospital was being randomly selected as the experimental hospital. A convenience sample of 184 Chinese pregnant women attending the childbirth education was recruited between October 2005 and April 2007. Inclusion criteria were primiparous with singleton and uneventful pregnancy, at gestation between 12 and 35 weeks, and did not have a past or familial psychiatric illness. The intervention was a childbirth psychoeducation program that was incorporated into the routine childbirth education in the experimental hospital. The experimental group (n=92) received the childbirth psychoeducation program and the routine childbirth education. The comparison group (n=92) received the routine childbirth education alone in the comparison hospital. Outcomes were measured by the Self-Control Schedule, Parenting Sense of Competence Scale-Efficacy subscale and Edinburgh Postnatal Depression Scale at baseline, immediately post-intervention, at 6 weeks and 6 months postpartum. Analysis was by intention to treat. Women receiving the childbirth psychoeducation program had significant improvement in learned resourcefulness at 6 weeks postpartum (p=0.004) and an overall reduction in depressive

  15. Building sustainable organizational capacity to deliver HIV programs in resource-constrained settings: stakeholder perspectives.

    Science.gov (United States)

    Sharma, Anjali; Chiliade, Philippe; Michael Reyes, E; Thomas, Kate K; Collens, Stephen R; Rafael Morales, José

    2013-12-13

    In 2008, the US government mandated that HIV/AIDS care and treatment programs funded by the US President's Emergency Plan for AIDS Relief (PEPFAR) should shift from US-based international partners (IPs) to registered locally owned organizations (local partners, or LPs). The US Health Resources and Services Administration (HRSA) developed the Clinical Assessment for Systems Strengthening (ClASS) framework for technical assistance in resource-constrained settings. The ClASS framework involves all stakeholders in the identification of LPs' strengths and needs for technical assistance. This article examines the role of ClASS in building capacity of LPs that can endure and adapt to changing financial and policy environments. All stakeholders (n=68) in Kenya, Zambia, and Nigeria who had participated in the ClASS from LPs and IPs, the US Centers for Disease Control and Prevention (CDC), and, in Nigeria, HIV/AIDS treatment facilities (TFs) were interviewed individually or in groups (n=42) using an open-ended interview guide. Thematic analysis revealed stakeholder perspectives on ClASS-initiated changes and their sustainability. Local organizations were motivated to make changes in internal operations with the ClASS approach, PEPFAR's competitive funding climate, organizational goals, and desired patient health outcomes. Local organizations drew on internal resources and, if needed, technical assistance from IPs. Reportedly, ClASS-initiated changes and remedial action plans made LPs more competitive for PEPFAR funding. LPs also attributed their successful funding applications to their preexisting systems and reputation. Bureaucracy, complex and competing tasks, and staff attrition impeded progress toward the desired changes. Although CDC continues to provide technical assistance through IPs, declining PEPFAR funds threaten the consolidation of gains, smooth program transition, and continuity of treatment services. The well-timed adaptation and implementation of Cl

  16. Building sustainable organizational capacity to deliver HIV programs in resource-constrained settings: stakeholder perspectives

    Directory of Open Access Journals (Sweden)

    Anjali Sharma

    2013-12-01

    Full Text Available Background: In 2008, the US government mandated that HIV/AIDS care and treatment programs funded by the US President's Emergency Plan for AIDS Relief (PEPFAR should shift from US-based international partners (IPs to registered locally owned organizations (local partners, or LPs. The US Health Resources and Services Administration (HRSA developed the Clinical Assessment for Systems Strengthening (ClASS framework for technical assistance in resource-constrained settings. The ClASS framework involves all stakeholders in the identification of LPs’ strengths and needs for technical assistance. Objective: This article examines the role of ClASS in building capacity of LPs that can endure and adapt to changing financial and policy environments. Design: All stakeholders (n=68 in Kenya, Zambia, and Nigeria who had participated in the ClASS from LPs and IPs, the US Centers for Disease Control and Prevention (CDC, and, in Nigeria, HIV/AIDS treatment facilities (TFs were interviewed individually or in groups (n=42 using an open-ended interview guide. Thematic analysis revealed stakeholder perspectives on ClASS-initiated changes and their sustainability. Results: Local organizations were motivated to make changes in internal operations with the ClASS approach, PEPFAR's competitive funding climate, organizational goals, and desired patient health outcomes. Local organizations drew on internal resources and, if needed, technical assistance from IPs. Reportedly, ClASS-initiated changes and remedial action plans made LPs more competitive for PEPFAR funding. LPs also attributed their successful funding applications to their preexisting systems and reputation. Bureaucracy, complex and competing tasks, and staff attrition impeded progress toward the desired changes. Although CDC continues to provide technical assistance through IPs, declining PEPFAR funds threaten the consolidation of gains, smooth program transition, and continuity of treatment services

  17. Water Resources Research Grant Program project descriptions, fiscal year 1987

    Science.gov (United States)

    ,

    1987-01-01

    This report contains information on the 34 new projects funded by the United States Geological Survey 's Water Resources Research Grant Program in fiscal year 1987 and on 3 projects completed during the year. For the new projects, the report gives the grant number, project title, performing organization, principal investigator(s), and a project description that includes: (1) identification of water related problems and problem-solution approach (2) contribution to problem solution, (3) objectives, and (4) approach. The 34 projects include 12 in the area of groundwater quality problems, 12 in the science and technology of water quality management, 1 in climate variability and the hydrologic cycle, 4 in institutional change in water resources management, and 5 in surface water management. For the three completed projects, the report furnishes the grant number; project title; performing organization; principal investor(s); starting data; data of receipt of final report; and an abstract of the final report. Each project description provides the information needed to obtain a copy of the final report. The report contains tables showing: (1) proposals received according to area of research interest, (2) grant awards and funding according to area of research interest, (3) proposals received according to type of submitting organization, and (4) awards and funding according to type of organization. (Author 's abstract)

  18. Resource Isolation Method for Program’S Performance on CMP

    Science.gov (United States)

    Guan, Ti; Liu, Chunxiu; Xu, Zheng; Li, Huicong; Ma, Qiang

    2017-10-01

    Data center and cloud computing are more popular, which make more benefits for customers and the providers. However, in data center or clusters, commonly there is more than one program running on one server, but programs may interference with each other. The interference may take a little effect, however, the interference may cause serious drop down of performance. In order to avoid the performance interference problem, the mechanism of isolate resource for different programs is a better choice. In this paper we propose a light cost resource isolation method to improve program’s performance. This method uses Cgroups to set the dedicated CPU and memory resource for a program, aiming at to guarantee the program’s performance. There are three engines to realize this method: Program Monitor Engine top program’s resource usage of CPU and memory and transfer the information to Resource Assignment Engine; Resource Assignment Engine calculates the size of CPU and memory resource should be applied for the program; Cgroups Control Engine divide resource by Linux tool Cgroups, and drag program in control group for execution. The experiment result show that making use of the resource isolation method proposed by our paper, program’s performance can be improved.

  19. Demonstrating the value of a social science research program to a natural resource management agency

    Science.gov (United States)

    Pamela J. Jakes; John F. Dwyer; Deborah S. Carr

    1998-01-01

    With ever tightening resources to address an increased number of diverse and complex issues, it has become common for scientists and managers to be called upon to demonstrate the value of their programs. In the spring of 1995, social scientists at the USDA Forest Service North Central Forest Experiment Station we so called upon. This paper discusses an effort to...

  20. Current Status of Human Resource Training Program for Fostering RIBiomics Professionals

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong-Eun; Jang, Beom-Su; Choi, Dae Seong [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Park, Tai-jin [Radiation Research Division, Korea Radioisotope Association, Seoul 132-822, Republic of Korea (Korea, Republic of); Park, Sang Hyun [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Radiation Research Division, Korea Radioisotope Association, Seoul 132-822, Republic of Korea (Korea, Republic of); Department of Radiobiotechnology and Applied Radioisotope Science, Korea University of Science and Technology, Deajeon 305-350 (Korea, Republic of)

    2015-07-01

    training program for fostering RI-Biomics professionals in the following key fields; (1) Radio-pharmaceuticals synthesis and labeled compound development, (2) Development of RI-ADME in the living object and image assessment technology. Personnel training program that carries out theoretical education and practical training in the field related to RI-Biomics in parallel is being conducted. Internship training for university students has been administered twice already while educational program for the existing professionals in the RI-Biomics field will be carried out during the summer of 2014. The human resource training program for combination of RIADME and different molecular imaging techniques can offer synergistic advantages to facilitate understanding RIADME and fostering RI-ADME professionals. (authors)

  1. Current Status of Human Resource Training Program for Fostering RIBiomics Professionals

    International Nuclear Information System (INIS)

    Lee, Dong-Eun; Jang, Beom-Su; Choi, Dae Seong; Park, Tai-jin; Park, Sang Hyun

    2015-01-01

    training program for fostering RI-Biomics professionals in the following key fields; (1) Radio-pharmaceuticals synthesis and labeled compound development, (2) Development of RI-ADME in the living object and image assessment technology. Personnel training program that carries out theoretical education and practical training in the field related to RI-Biomics in parallel is being conducted. Internship training for university students has been administered twice already while educational program for the existing professionals in the RI-Biomics field will be carried out during the summer of 2014. The human resource training program for combination of RIADME and different molecular imaging techniques can offer synergistic advantages to facilitate understanding RIADME and fostering RI-ADME professionals. (authors)

  2. The Nuclear Power Institute Programs for Human Resource Development for the Nuclear Industry

    International Nuclear Information System (INIS)

    Peddicord, K.L.

    2014-01-01

    Principal conclusions: 1. NPI is a full-scope, end-to-end, integrated approach to human resource development. Participation of government and government agencies, and elected officials and decision makers is vital. These key individuals and organizations encourage the effort, and provide support, a voice and advocacy for NPI and its programs. 2. Critical role of vocational training. The majority of the workforce does not involve only B.S. level engineers, but are graduates from two-year programs that are developed in collaboration with industry that prepare them for careers as technologists and technicians at a nuclear power plant. 3. In education and training, education is only part of the story. Collaboration with industry results in: – curricula, material, inputs and programs, – opportunities for students to benefit from industry mentors and get onsite experience, and – work on real-world, industry defined problems. 4. Outreach is instrumental in: –engaging with the next generation both for support of nuclear power and in building the workforce, and –generating vital contacts with the community to foster public understanding and acceptance of nuclear energy

  3. The transition to medication adoption in publicly funded substance use disorder treatment programs: organizational structure, culture, and resources.

    Science.gov (United States)

    Knudsen, Hannah K; Roman, Paul M

    2014-05-01

    Medications for the treatment of substance use disorders (SUDs) are not widely available in publicly funded SUD treatment programs. Few studies have drawn on longitudinal data to examine the organizational characteristics associated with programs transitioning from not delivering any pharmacotherapy to adopting at least one SUD medication. Using two waves of panel longitudinal data collected over a 5-year period, we measured the transition to medication adoption in a cohort of 190 publicly funded treatment organizations that offered no SUD medications at baseline. Independent variables included organizational characteristics, medical resources, funding, treatment culture, and detailing activities by pharmaceutical companies. Of 190 programs not offering SUD pharmacotherapy at baseline, 22.6% transitioned to offering at least one SUD medication at follow-up approximately 5 years later. Multivariate logistic regression results indicated that the employment of at least one physician at baseline, having a greater proportion of Medicaid clients, and pharmaceutical detailing were positively associated with medication adoption. Adoption of pharmacotherapy was more likely in programs that had greater medical resources, Medicaid funding, and contact with pharmaceutical companies. Given the potential expansion of Medicaid under the Affordable Care Act, patients served by publicly funded programs may gain greater access to such treatments, but research is needed to document health reform's impact on this sector of the treatment system.

  4. A Review of Ocean Management and Integrated Resource Management Programs from Around the World

    OpenAIRE

    , Seaplan

    2018-01-01

    This draft report is one of several prepared under contract to the Massachusetts Ocean Partnership (MOP) to support the Massachusetts Executive Office of Energy and Environmental Affairs (EOEEA) in its development of the integrated coastal ocean management plan mandated by the Massachusetts Oceans Act of 2008. The purpose of this report was to inventory and review ocean management and integrated resource management programs from around the world, including the United States, Europe, Australia...

  5. Technical-Oriented Enterprise Resource Planning (ERP) Body of Knowledge for Information Systems Programs: Content and Implementation

    Science.gov (United States)

    Boyle, Todd A.

    2007-01-01

    In this article, the author proposes a body of knowledge that the educators can use to incorporate the technical aspects of enterprise resource planning (ERP) into an information systems (IS) program, encapsulated as the ERP technical knowledge framework. To illustrate the application of this framework, the author discusses a course sequence that…

  6. Sudan Country Profile - Human Resource Development (HRD) for the first Nuclear Power Program

    International Nuclear Information System (INIS)

    Yousif, Eltayeb H. Elneel

    2014-01-01

    Sudan has been decided to prepare a strategy plan for the first nuclear power plant for various reasons like production electricity and increase the national industries besides the capabilities to do the scientific and research activities. Sudan has been started to establish and develop a master plan for the human resource development and makes a comprehensive realistic assessment about the organizational, educational and industrial capabilities and determines the requirements for developing the quality and quantity of human resources needed. The national nuclear regulatory authority has been started to update all legislation and regulations and also reviews and evaluates the international agreements and conventions related to the nuclear energy. In this profile we used the methodology of the international atomic energy agency to assess and evaluate the capacity building in Sudan. The expected outcomes from this profile are identified the gaps regarding the strengthening the national infrastructure and nuclear regulatory framework and issuing regulations to met the requirements for safety and security of the nuclear power plant. The availability of the human resources skills are important for effectively monitors the activities of the companies and facilities involved in nuclear power plant. The new nuclear law and the new national policy of the nuclear program are now under the process of approval.(author)

  7. Primer on gas integrated resource planning

    Energy Technology Data Exchange (ETDEWEB)

    Goldman, C.; Comnes, G.A.; Busch, J.; Wiel, S. [Lawrence Berkeley Lab., CA (United States)

    1993-12-01

    This report discusses the following topics: gas resource planning: need for IRP; gas integrated resource planning: methods and models; supply and capacity planning for gas utilities; methods for estimating gas avoided costs; economic analysis of gas utility DSM programs: benefit-cost tests; gas DSM technologies and programs; end-use fuel substitution; and financial aspects of gas demand-side management programs.

  8. Optimizing conjunctive use of surface water and groundwater resources with stochastic dynamic programming

    DEFF Research Database (Denmark)

    Davidsen, Claus; Liu, Suxia; Mo, Xinguo

    2014-01-01

    . A stochastic dynamic programming (SDP) approach is used to minimize the basin-wide total costs arising from water allocations and water curtailments. Dynamic allocation problems with inclusion of groundwater resources proved to be more complex to solve with SDP than pure surface water allocation problems due...... to head-dependent pumping costs. These dynamic pumping costs strongly affect the total costs and can lead to non-convexity of the future cost function. The water user groups (agriculture, industry, domestic) are characterized by inelastic demands and fixed water allocation and water supply curtailment...

  9. A Fuzzy Max–Min Decision Bi-Level Fuzzy Programming Model for Water Resources Optimization Allocation under Uncertainty

    Directory of Open Access Journals (Sweden)

    Chongfeng Ren

    2018-04-01

    Full Text Available Water competing conflict among water competing sectors from different levels should be taken under consideration during the optimization allocation of water resources. Furthermore, uncertainties are inevitable in the optimization allocation of water resources. In order to deal with the above problems, this study developed a fuzzy max–min decision bi-level fuzzy programming model. The developed model was then applied to a case study in Wuwei, Gansu Province, China. In this study, the net benefit and yield were regarded as the upper-level and lower-level objectives, respectively. Optimal water resource plans were obtained under different possibility levels of fuzzy parameters, which could deal with water competing conflict between the upper level and the lower level effectively. The obtained results are expected to make great contribution in helping local decision-makers to make decisions on dealing with the water competing conflict between the upper and lower level and the optimal use of water resources under uncertainty.

  10. Human resource development for a community-based health extension program: a case study from Ethiopia.

    Science.gov (United States)

    Teklehaimanot, Hailay D; Teklehaimanot, Awash

    2013-08-20

    Ethiopia is one of the sub-Saharan countries most affected by high disease burden, aggravated by a shortage and imbalance of human resources, geographical distance, and socioeconomic factors. In 2004, the government introduced the Health Extension Program (HEP), a primary care delivery strategy, to address the challenges and achieve the World Health Organization Millennium Development Goals (MDGs) within a context of limited resources. The health system was reformed to create a platform for integration and institutionalization of the HEP with appropriate human capacity, infrastructure, and management structures. Human resources were developed through training of female health workers recruited from their prospective villages, designed to limit the high staff turnover and address gender, social and cultural factors in order to provide services acceptable to each community. The service delivery modalities include household, community and health facility care. Thus, the most basic health post infrastructure, designed to rapidly and cost-effectively scale up HEP, was built in each village. In line with the country's decentralized management system, the HEP service delivery is under the jurisdiction of the district authorities. The nationwide implementation of HEP progressed in line with its target goals. In all, 40 training institutions were established, and over 30,000 Health Extension Workers have been trained and deployed to approximately 15,000 villages. The potential health service coverage reached 92.1% in 2011, up from 64% in 2004. While most health indicators have improved, performance in skilled delivery and postnatal care has not been satisfactory. While HEP is considered the most important institutional framework for achieving the health MDGs in Ethiopia, quality of service, utilization rate, access and referral linkage to emergency obstetric care, management, and evaluation of the program are the key challenges that need immediate attention. This article

  11. Hydrogen research and development in Hawaii: Hawaii natural energy institute's hydrogen from renewable resources research program

    International Nuclear Information System (INIS)

    McKinley, K.R.; Rocheleau, R.E.; Takahashi, P.K.; Jensen, C.M.

    1993-01-01

    Hawaii, an energy-vulnerable state, has launched a Renewable Resources Research Program, focusing on hydrogen production and storage; the main tasks of this effort are: photoelectrochemical production of hydrogen through the use of coated silicon electrodes; solar conversion and the production of hydrogen with cyanobacteria; improved hydrogen storage through the use of nonclassical poly-hydride metal complexes. 10 refs

  12. NURE aerial gamma ray and magnetic reconnaissance survey, Thorpe area, Newark NK18-11 Quadrangle. Volume I. Narrative report

    International Nuclear Information System (INIS)

    1977-11-01

    During the flying seasons of 1976 and 1977 LKB Resources, Inc. conducted a rotary wing combined airborne high sensitivity gamma-ray and magnetic survey of four 1:250,000 quadrangles covering portions of Pennsylvania, New Jersey, and New York. The airborne system, field operations, data reduction, gamma-ray and magnetic data presentation, geology and uranium deposits of the Thorpe Area, photogeologic enhancement study of the Thorpe Area, and data interpretation are discussed

  13. Medical education resources initiative for teens program in baltimore: A model pipeline program built on four pillars.

    Science.gov (United States)

    Mains, Tyler E; Wilcox, Mark V; Wright, Scott M

    2016-01-01

    Less than 6% of U.S. medical school applicants are African-American. The lack of diversity among physicians, by race as well as other measures, confers a negative impact on the American healthcare system because underrepresented minority (URM) physicians are more likely to practice in underserved communities and deliver more equitable, culturally competent care. MERIT (Medical Education Resources Initiative for Teens) is a nonprofit organization based in Baltimore, Maryland, USA. MERIT prepares URM high school students for health careers by providing a holistic support system for seven consecutive years. The program model, which utilizes weekly Saturday sessions, summer internships, and longitudinal mentoring, is built on four foundational pillars: (1) Ignite the Fire, (2) Illuminate the Path, (3) Create the Toolkit, and (4) Sustain the Desire. Since 2011, MERIT has supported 51 students in the Baltimore City Public School System. For the past two years, 100% (n = 14) of MERIT seniors enrolled in universities, compared to only 20.2% of Baltimore City students overall. While it is too early to know whether MERIT alumni will realize their goals of becoming healthcare professionals, they are currently excelling in universities and over 75% (n = 17) are still planning to pursue graduate degrees in health-related fields. After piloting an effective program model, MERIT now has three key priorities moving forward: (1) Creating a sustainable and thriving organization, (2) increasing the number of scholars the program supports in Baltimore, and (3) expanding MERIT to other cities.

  14. Completing the land resource hierarchy

    Science.gov (United States)

    The Land Resource Hierarchy of the NRCS is a hierarchal landscape classification consisting of resource areas which represent both conceptual and spatially discrete landscape units stratifying agency programs and practices. The Land Resource Hierarchy (LRH) scales from discrete points (soil pedon an...

  15. Integrating Research and Extension for the Nsf-Reu Program in Water Resources

    Science.gov (United States)

    Judge, J.; Migliaccio, K.; Gao, B.; Shukla, S.; Ehsani, R.; McLamore, E.

    2011-12-01

    Providing positive and meaningful research experiences to students in their undergraduate years is critical for motivating them to pursue advanced degrees or research careers in science and engineering. Such experiences not only offer training for the students in problem solving and critical thinking via hands-on projects, but also offer excellent mentoring and recruiting opportunities for the faculty advisors. The goal of the Research Experience for Undergraduates (REU) Program in the Agricultural and Biological Engineering Department (ABE) at the University of Florida (UF) is to provide eight undergraduate students a unique opportunity to conduct research in water resources using interdisciplinary approaches, integrating research and extension. The students are selected from diverse cultural and educational backgrounds. The eight-week REU Program utilizes the extensive infrastructure of UF - Institute of Food and Agricultural Sciences (IFAS) through the Research and Education Centers (RECs). Two students are paired to participate in their own project under the direct supervision of one of the four research mentors. Four of the eight students are located at the main campus, in Gainesville, Fl, and four remaining students are located off-campus, at the RECs, where some of the ABE faculty are located. The students achieve an enriching cohort experience through social networking, daily blogs, and weekly video conferences to share their research and other REU experiences. The students are co-located during the Orientation week and also during the 5-day Florida Waters Tour. Weekly group meetings and guest lectures are conducted via synchronously through video conferencing. The integration of research and extension is naturally achieved through the projects at the RECs, the guest lectures, Extension workshops, and visits to the Water Management Districts in Florida. In the last two years of the Program, we have received over 80 applicants, from four-year and advanced

  16. Resource control of object-oriented programs

    OpenAIRE

    Marion, Jean-Yves; Pechoux, Romain

    2007-01-01

    International audience; A sup-interpretation is a tool which provides an upper bound on the size of a value computed by some symbol of a program. Sup-interpretations have shown their interest to deal with the complexity of first order functional programs. For instance, they allow to characterize all the functions bitwise computable in \\texttt{Alogtime}. This paper is an attempt to adapt the framework of sup-interpretations to a fragment of oriented-object programs, including distinct encoding...

  17. Resource Contingency Program - Oregon : Final Environmental Impact Statement, Hermiston Power Project.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1995-09-01

    The Bonneville Power Administration (BPA) has statutory responsibilities to supply electrical power to its utility, industrial, and other customers in the Pacific Northwest. In 1990, to cover the outer range of potential load growth with new resources, BPA embarked upon the Resource Contingency Program (RCP). Instead of buying or building generating plants now, BPA has purchased options to acquire power later, if and when it is needed. The decision to acquire any of these option energy projects to fulfill statutory supply obligations will be influenced by Federal system load growth, the outcome of BPA`s Business Plan, required operational changes in Columbia-Snake River Hydroelectric facilities, and the loss of major generating resources. In September 1993, three option development agreements were signed with three proposed natural gas-fired, combined cycle combustion turbine CT projects near Chehalis and Satsop, Washington, and near Hermiston, Oregon. Together these three projects could supply BPA with 1,090 average megawatts (aMW) of power. Under these agreements, sponsors are obtaining permits and conducting project design work, and BPA is completing this EIS process. In September 1993, BPA published a Notice of Intent to prepare an environmental impact statement (EIS) on these three proposed gas-fired combustion turbine projects and held public scoping meetings in October 1993 at each site. In February 1994, BPA released an Implementation Plan on the proposed scope of the EIS. A draft EIS on the three proposed projects was published in February 1995. The impacts of the Chehalis and Satsop projects located in Washington State will be covered in one EIS document, while the impacts of the Hermiston project located in Oregon are covered in this final EIS document. It is BPA`s intent to continue to base the analysis of impacts on the assumption that all three projects may be constructed at some point in the future.

  18. Resource contingency program - Oregon. Final environmental impact statement, Hermiston power project

    International Nuclear Information System (INIS)

    1995-09-01

    The Bonneville Power Administration (BPA) has statutory responsibilities to supply electrical power to its utility, industrial, and other customers in the Pacific Northwest. In 1990, to cover the outer range of potential load growth with new resources, BPA embarked upon the Resource Contingency Program (RCP). Instead of buying or building generating plants now, BPA has purchased options to acquire power later, if and when it is needed. The decision to acquire any of these option energy projects to fulfill statutory supply obligations will be influenced by Federal system load growth, the outcome of BPA's Business Plan, required operational changes in Columbia-Snake River Hydroelectric facilities, and the loss of major generating resources. In September 1993, three option development agreements were signed with three proposed natural gas-fired, combined cycle combustion turbine CT projects near Chehalis and Satsop, Washington, and near Hermiston, Oregon. Together these three projects could supply BPA with 1,090 average megawatts (aMW) of power. Under these agreements, sponsors are obtaining permits and conducting project design work, and BPA is completing this EIS process. In September 1993, BPA published a Notice of Intent to prepare an environmental impact statement (EIS) on these three proposed gas-fired combustion turbine projects and held public scoping meetings in October 1993 at each site. In February 1994, BPA released an Implementation Plan on the proposed scope of the EIS. A draft EIS on the three proposed projects was published in February 1995. The impacts of the Chehalis and Satsop projects located in Washington State will be covered in one EIS document, while the impacts of the Hermiston project located in Oregon are covered in this final EIS document. It is BPA's intent to continue to base the analysis of impacts on the assumption that all three projects may be constructed at some point in the future

  19. Promotion of Bilateral Cooperative Programs in Nuclear Human Resources Development

    Energy Technology Data Exchange (ETDEWEB)

    Lee, E. J.; Han, K. W.; Nam, Y. M. (and others)

    2009-08-15

    The purpose of this project is strengthening of bilateral cooperation with those countries for sharing Korea's technology, and providing of education and training on Korean experience regarding national nuclear policy, technology self reliance, and technology itself, in the field of nuclear power generation and the application of radioisotopes and radiation. This project covers an analysis on the need of nuclear human resource development in countries having interest in the introduction of nuclear power and/or promotion of the use of nuclear energy, and provision of courses on 'nuclear power policy, planning and management' and 'design and operation of nuclear research reactor, and application of radiation technology' along with the country specific needs. Education and training of key members in nuclear energy development from Egypt: It was implemented through bilateral cooperation and support by KOICA program. The first part, which targeted staff members from Egypt Nuclear Commission, was held for 2 months providing a KOICA course on policy, planning and management for nuclear power project, and second part was on the job training in Korea Hydro and Nuclear Power and Korea Institute of Nuclear Safety, KAERI respectively. On the job training of 1 scientist from Vietnam was implemented on the basis of bilateral cooperation in a research laboratory on radioactive waste treatment technology, at KAERI. Education and training for scientists from South East RCA countries were carried out for 11 participants from Vietnam, Thailand, Indonesia, China, Pakistan, Malaysia, Philippines, and Bangladesh. The course dealt with nuclear research reactor and radiation application technology. Development of nuclear education and training programs for key persons involved in nuclear power projects from countries of Middle East: The developed program consists of 15 courses addressing 3 technical levels, i.e. high level policy makers, middle level project

  20. Promotion of Bilateral Cooperative Programs in Nuclear Human Resources Development

    International Nuclear Information System (INIS)

    Lee, E. J.; Han, K. W.; Nam, Y. M.

    2009-08-01

    The purpose of this project is strengthening of bilateral cooperation with those countries for sharing Korea's technology, and providing of education and training on Korean experience regarding national nuclear policy, technology self reliance, and technology itself, in the field of nuclear power generation and the application of radioisotopes and radiation. This project covers an analysis on the need of nuclear human resource development in countries having interest in the introduction of nuclear power and/or promotion of the use of nuclear energy, and provision of courses on 'nuclear power policy, planning and management' and 'design and operation of nuclear research reactor, and application of radiation technology' along with the country specific needs. Education and training of key members in nuclear energy development from Egypt: It was implemented through bilateral cooperation and support by KOICA program. The first part, which targeted staff members from Egypt Nuclear Commission, was held for 2 months providing a KOICA course on policy, planning and management for nuclear power project, and second part was on the job training in Korea Hydro and Nuclear Power and Korea Institute of Nuclear Safety, KAERI respectively. On the job training of 1 scientist from Vietnam was implemented on the basis of bilateral cooperation in a research laboratory on radioactive waste treatment technology, at KAERI. Education and training for scientists from South East RCA countries were carried out for 11 participants from Vietnam, Thailand, Indonesia, China, Pakistan, Malaysia, Philippines, and Bangladesh. The course dealt with nuclear research reactor and radiation application technology. Development of nuclear education and training programs for key persons involved in nuclear power projects from countries of Middle East: The developed program consists of 15 courses addressing 3 technical levels, i.e. high level policy makers, middle level project implementers, and beginners

  1. Dark Skies are a Universal Resource: Programs Planned for the International Year of Astronomy

    Science.gov (United States)

    Walker, Constance E.; US IYA Dark Skies Working Group

    2008-05-01

    The dark night sky is a natural resource that is being lost by much of the world's population. This loss is a growing, serious issue that impacts not only astronomical research, but also human health, ecology, safety, economics and energy conservation. One of the themes of the US Node targeted for the International Year of Astronomy (IYA) is "Dark Skies are a Universal Resource". The goal is to raise public awareness of the impact of artificial lighting on local environments by getting people involved locally in a variety of dark skies-related events. To reach this goal, activities are being developed that: 1) Teach about dark skies using new technology (e.g., an activity-based planetarium show on DVD, podcasting, social networking) 2) Provide thematic events on light pollution at star parties and observatory open houses (Dark Skies Teaching Sites, Astronomy Nights in the (National) Parks, Sidewalk Astronomy Nights) 3) Organize events in the arts (e.g., a photography contest) 4) Involve citizen-scientists in unaided-eye and digital-meter star counting programs (e.g., GLOBE at Night, "How Many Stars?” and the Great World Wide Star Count) and 5) Raise awareness about the link between light pollution and public health, economic issues, ecological consequences, energy conservation, safety and security (e.g., The Great Switch Out, Earth Hour, National Dark Skies Week, traveling exhibits and a 6-minute video tutorial on lighting issues). To deliver these programs, strategic networks have been established with the ASP's Night Sky Network's astronomy clubs, Astronomy from the Ground Up's science and nature centers and the Project and Family ASTRO programs, as well as the International Dark-Sky Association, GLOBE and the Astronomical League, among others. The poster presentation will outline the activities being developed, the plans for funding, implementation, marketing and the connections to the global cornerstone IYA project, "Dark Skies Awareness".

  2. A crew resource management program tailored to trauma resuscitation improves team behavior and communication.

    Science.gov (United States)

    Hughes, K Michael; Benenson, Ronald S; Krichten, Amy E; Clancy, Keith D; Ryan, James Patrick; Hammond, Christopher

    2014-09-01

    Crew Resource Management (CRM) is a team-building communication process first implemented in the aviation industry to improve safety. It has been used in health care, particularly in surgical and intensive care settings, to improve team dynamics and reduce errors. We adapted a CRM process for implementation in the trauma resuscitation area. An interdisciplinary steering committee developed our CRM process to include a didactic classroom program based on a preimplementation survey of our trauma team members. Implementation with new cultural and process expectations followed. The Human Factors Attitude Survey and Communication and Teamwork Skills assessment tool were used to design, evaluate, and validate our CRM program. The initial trauma communication survey was completed by 160 team members (49% response). Twenty-five trauma resuscitations were observed and scored using Communication and Teamwork Skills. Areas of concern were identified and 324 staff completed our 3-hour CRM course during a 3-month period. After CRM training, 132 communication surveys and 38 Communication and Teamwork Skills observations were completed. In the post-CRM survey, respondents indicated improvement in accuracy of field to medical command information (p = 0.029); accuracy of emergency department medical command information to the resuscitation area (p = 0.002); and team leader identity, communication of plan, and role assignment (p = 0.001). After CRM training, staff were more likely to speak up when patient safety was a concern (p = 0.002). Crew Resource Management in the trauma resuscitation area enhances team dynamics, communication, and, ostensibly, patient safety. Philosophy and culture of CRM should be compulsory components of trauma programs and in resuscitation of injured patients. Copyright © 2014 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  3. Results from utility wind resource assessment programs in Nebraska, Colorado, and Arizona

    Energy Technology Data Exchange (ETDEWEB)

    Drapeau, C.L. [Global Energy Concepts, Inc., Bothell, WA (United States)

    1997-12-31

    Global Energy Concepts (GEC) has been retained by utilities in Colorado, Nebraska, and Arizona to site, install, and operate 21 wind monitoring stations as part of the Utility Wind Resource Assessment Program (U*WRAP). Preliminary results indicate wind speed averages at 40 meters (132 ft) of 6.5 - 7.4 m/s (14.5-16.5 mph) in Nebraska and 7.6 - 8.9 m/s (17.0-19.9 mph) in Colorado. The Arizona stations are not yet operational. This paper presents the history and current status of the 21 monitoring stations as well as preliminary data results. Information on wind speeds, wind direction, turbulence intensity, wind shear, frequency distribution, and data recovery rates are provided.

  4. Annual Report: EPAct Complementary Program's Ultra-Deepwater R&D Portfolio and Unconventional Resources R&D Portfolio (30 September 2012)

    Energy Technology Data Exchange (ETDEWEB)

    none,; Rose, Kelly [NETL; Hakala, Alexandra [NETL; Guthrie, George [NETL

    2012-09-30

    This report summarizes FY13 research activities performed by the National Energy Technology Laboratory (NETL), Office of Research and Development (ORD), along with its partners in the Regional University Alliance (RUA) to fulfill research needs under the Energy Policy Act of 2005 (EPAct) Section 999's Complementary Program. Title IX, Subtitle J, Section 999A(d) of EPAct 2005 authorizes $50 million per year of federal oil and gas royalties, rents and bonus payments for an oil and natural gas research and development effort, the Ultra-Deepwater and Unconventional Natural Gas and Other Petroleum Resources Research Program. Section 999 further prescribes four program elements for the effort, one of which is the Complementary Research Program that is to be performed by NETL. This document lays out the plan for the research portfolio for the Complementary Research Program, with an emphasis on the 2013 funding. The Complementary Program consists of two research portfolios focused on domestic resources: (1) the Deepwater and Ultra-Deepwater Portfolio (UDW) (focused on hydrocarbons in reservoirs in extreme environments) and (2) the Unconventional Resources Portfolio (UCR) (focused on hydrocarbons in shale reservoirs). These two portfolios address the science base that enables these domestic resources to be produced responsibly, informing both regulators and operators. NETL is relying on a core Department of Energy-National Energy Technology Laboratory (DOE-NETL) competency in engineered-natural systems to develop this science base, allowing leveraging of decades of investment. NETL's Complementary Research Program research portfolios support the development of unbiased research and information for policymakers and the public, performing rapid predictions of possible outcomes associated with unexpected events, and carrying out quantitative assessments for energy policy stakeholders that accurately integrate the risks of safety and environmental impacts. The

  5. The Development of an Individualized Instructional Program in Beginning College Mathematics Utilizing Computer Based Resource Units. Final Report.

    Science.gov (United States)

    Rockhill, Theron D.

    Reported is an attempt to develop and evaluate an individualized instructional program in pre-calculus college mathematics. Four computer based resource units were developed in the areas of set theory, relations and function, algebra, trigonometry, and analytic geometry. Objectives were determined by experienced calculus teachers, and…

  6. National logging program for the National Uranium Resource Evaluation. Final report

    International Nuclear Information System (INIS)

    The Mineral Engineering Division (MED) of High Life Helicopters, Inc., operated from May, 1979, through August, 1981, as a subcontractor to the Department of Energy (DOE) to acquire downhole geophysical log information in support of the National Uranium Resource Evaluation program (NURE). MED acquired downhole geophysical log information in 26 1 0 x 2 0 NTMS quadrangles in Colorado, Montana, Nebraska, North Dakota, South Dakota, and Wyoming. MED obtained the log information by gaining permission to log oil and gas wells, water wells, and coal exploration holes. Actual geophysical logging was subcontracted to Century Geophysical Corporation. After logging of each well and completed, MED submitted the log information and other pertinent data to Bendix Field Engineering Corporation (BFEC) for evaluation. MED collected over 700,000 feet of geophysical logs. Additionally, MED conducted a search of log libraries for existing log data for twelve of the quadrangles included in the program. It should be noted that ERTEC, Inc. conducted geophysical logging and a log library search to five quadrangles in Wyoming. These areas were later assigned to MED. The location of all wells logged by MED and ERTEC and the location of other log data is shown on the enclosed maps. Detailed information that pertains to each well is provided following each map

  7. Distributed energy resources management using plug-in hybrid electric vehicles as a fuel-shifting demand response resource

    International Nuclear Information System (INIS)

    Morais, H.; Sousa, T.; Soares, J.; Faria, P.; Vale, Z.

    2015-01-01

    Highlights: • Definition fuel shifting demand response programs applied to the electric vehicles. • Integration of the proposed fuel shifting in energy resource management algorithm. • Analysis of fuel shifting contribution to support the consumption increasing. • Analysis of fuel shifting contribution to support the electric vehicles growing. • Sensitivity analysis considering different electric vehicles penetration levels. - Abstract: In the smart grids context, distributed energy resources management plays an important role in the power systems’ operation. Battery electric vehicles and plug-in hybrid electric vehicles should be important resources in the future distribution networks operation. Therefore, it is important to develop adequate methodologies to schedule the electric vehicles’ charge and discharge processes, avoiding network congestions and providing ancillary services. This paper proposes the participation of plug-in hybrid electric vehicles in fuel shifting demand response programs. Two services are proposed, namely the fuel shifting and the fuel discharging. The fuel shifting program consists in replacing the electric energy by fossil fuels in plug-in hybrid electric vehicles daily trips, and the fuel discharge program consists in use of their internal combustion engine to generate electricity injecting into the network. These programs are included in an energy resources management algorithm which integrates the management of other resources. The paper presents a case study considering a 37-bus distribution network with 25 distributed generators, 1908 consumers, and 2430 plug-in vehicles. Two scenarios are tested, namely a scenario with high photovoltaic generation, and a scenario without photovoltaic generation. A sensitivity analyses is performed in order to evaluate when each energy resource is required

  8. Yucca Mountain Biological Resources Monitoring Program

    International Nuclear Information System (INIS)

    1992-01-01

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a possible site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a repository. To ensure that site characterization activities (SCA) do not adversely affect the Yucca Mountain area, an environmental program has been implemented to monitor and mitigate potential impacts and to ensure that activities comply with applicable environmental regulations. This report describes the activities and accomplishments during fiscal year 1991 (FY91) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Activities Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

  9. Learning to Thrive: Building Diverse Scientists’ Access to Community and Resources through the BRAINS Program

    Science.gov (United States)

    Margherio, Cara; Horner-Devine, M. Claire; Mizumori, Sheri J. Y.; Yen, Joyce W.

    2016-01-01

    BRAINS: Broadening the Representation of Academic Investigators in NeuroScience is a National Institutes of Health–funded, national program that addresses challenges to the persistence of diverse early-career neuroscientists. In doing so, BRAINS aims to advance diversity in neuroscience by increasing career advancement and retention of post-PhD, early-career neuroscientists from underrepresented groups (URGs). The comprehensive professional development program is structured to catalyze conversations specific to URGs in neuroscience and explicitly addresses factors known to impact persistence such as a weak sense of belonging to the scientific community, isolation and solo status, inequitable access to resources that impact career success, and marginalization from informal networks and mentoring relationships. While we do not yet have data on the long-term impact of the BRAINS program on participants’ career trajectory and persistence, we introduce the BRAINS program theory and report early quantitative and qualitative data on shorter-term individual impacts within the realms of career-advancing behaviors and career experiences. These early results suggest promising, positive career productivity, increased self-efficacy, stronger sense of belonging, and new perspectives on navigating careers for BRAINS participants. We finish by discussing recommendations for future professional development programs and research designed to broaden participation in the biomedical and life sciences. PMID:27587858

  10. Research Resources Survey: Radiology Junior Faculty Development.

    Science.gov (United States)

    Krupinski, Elizabeth A; Votaw, John R

    2015-07-01

    To assess resources available to junior faculty in US academic radiology departments for research mentorship and funding opportunities and to determine if certain resources are more common in successful programs. An anonymous survey covering scientific environment and research mentorship and was sent to vice-chairs of research of radiology departments. Results were evaluated to identify practices of research programs with respect to mentorship, resources, and opportunities. Academy of Radiology Research's 2012 National Institutes of Health (NIH) grants and awards list was used to determine if environment and practices correlate with funding. There was a 51% response rate. A greater fraction of clinical faculty gets promoted from assistant to associate professor than research faculty. Research faculty overall submits more funding applications. Most programs support start-up costs and K-awards. Over half of the departments have a vice-chair for faculty development, and most have formal mentorship programs. Faculty members are expected to teach, engage in service, publish, and apply for and get research funding within 3 years of hire. Top-tier programs as judged by NIH awards have a combination of MDs who devote >50% effort to research and PhD faculty. Key factors holding back both clinical and research junior faculty development were motivation, resources, and time, although programs reported high availability of resources and support at the department level. Better marketing of resources for junior faculty, effort devoted to mentoring clinical faculty in research, and explicit milestones/expectations for achievement could enhance junior faculty success, promote interest in the clinician–scientist career path for radiologists, and lead to greater research success.

  11. California low-temperature geothermal resources update: 1993

    Energy Technology Data Exchange (ETDEWEB)

    Youngs, L.G.

    1994-12-31

    The US Department of Energy -- Geothermal Division (DOE/GD) recently sponsored the Low-Temperature Geothermal Resources and Technology Transfer Program to bring the inventory of the nation`s low- and moderate-temperature geothermal resources up to date and to encourage development of the resources. The Oregon Institute of Technology, Geo-Heat Center (OIT/GHC) and the University of Utah Research Institute (UURI) established subcontracts and coordinated the project with the state resource teams from the western states that participated in the program. The California Department of Conservation, Division of Mines and Geology (DMG) entered into contract numbered 1092--023(R) with the OIT/GHC to provide the California data for the program. This report is submitted in fulfillment of that contract.

  12. On the Cutting Edge Professional Development Program: Workshop and Web Resources for Current and Future Geoscience Faculty

    Science.gov (United States)

    MacDonald, R.; Manduca, C. A.; Mogk, D. W.; Tewksbury, B. J.

    2004-12-01

    Recognizing that many college and university faculty receive little formal training in teaching, are largely unaware of advances in research on teaching and learning, and face a variety of challenges in advancing in academic careers, the National Science Foundation-funded program On the Cutting Edge provides professional development for current and future faculty in the geosciences at various stages in their careers. The program includes a series of six multi-day workshops, sessions and one-day workshops at professional meetings, and a website with information about workshop opportunities and a variety of resources that bring workshop content to faculty (http://serc.carleton.edu/NAGTWorkshops). The program helps faculty improve their teaching and their job satisfaction by providing resources on instructional methods, geoscience content, and strategies for career planning. Workshop and website resources address innovative and effective practices in teaching, course design, delivery of instructional materials, and career planning, as well as approaches for teaching particular topics and strategies for starting and maintaining a research program in various institutional settings. Each year, special workshops for graduate students and post-doctoral fellows interested in academic careers and for early career faculty complement offerings on course design and emerging topics that are open to the full geoscience community. These special workshops include sessions on topics such as dual careers, gender issues, family-work balance, interviewing and negotiating strategies. The workshops serve as opportunities for networking and community building, with participants building connections with other participants as well as workshop leaders. Workshop participants reflect the full range of institutional diversity as well as ethnic and racial diversity beyond that of the geoscience faculty workforce. More than 40 percent of the faculty participants are female. Of the faculty

  13. Yucca Mountain biological resources monitoring program

    International Nuclear Information System (INIS)

    1993-02-01

    The US Department of Energy (DOE) is required by the Nuclear Waste Policy Act of 1982 (as amended in 1987) to study and characterize Yucca Mountain as a potential site for a geologic repository for high-level nuclear waste. During site characterization, the DOE will conduct a variety of geotechnical, geochemical, geological, and hydrological studies to determine the suitability of Yucca Mountain as a potential repository. To ensure that site characterization activities (SCA) do not adversely affect the environment at Yucca Mountain, an environmental program has been implemented to monitor and mitigate potential impacts and ensure activities comply with applicable environmental regulations. This report describes the activities and accomplishments of EG ampersand G Energy Measurements, Inc. (EG ampersand G/EM) during fiscal year 1992 (FY92) for six program areas within the Terrestrial Ecosystem component of the YMP environmental program. The six program areas are Site Characterization Effects, Desert Tortoises, Habitat Reclamation, Monitoring and Mitigation, Radiological Monitoring, and Biological Support

  14. Vaccination program in a resource-limited setting: A case study in the Philippines.

    Science.gov (United States)

    Chootipongchaivat, Sarocha; Chantarastapornchit, Varit; Kulpeng, Wantanee; Ceria, Joyce Anne; Tolentino, Niña Isabelle; Teerawattananon, Yot

    2016-09-14

    Implementing national-level vaccination programs involves long-term investment, which can be a significant financial burden, particularly in resource-limited settings. Although many studies have assessed the economic impacts of providing vaccinations, evidence on the positive and negative implications of human resources for health (HRH) is still lacking. Therefore, this study aims to estimate the HRH impact of introducing pneumococcal conjugate vaccine (PCV) using a model-based economic evaluation. This study adapted a Markov model from a prior study that was conducted in the Philippines for assessing the cost-effectiveness of 10-valent and 13-valent PCV compared to no vaccination. The Markov model was used for estimating the number of cases of pneumococcal-related diseases, categorized by policy options. HRH-related parameters were obtained from document reviews and interviews using the quantity, task, and productivity model (QTP model). The number of full-time equivalent (FTE) of general practitioners, nurses, and midwives increases significantly if the universal vaccine coverage policy is implemented. A universal coverage of PCV13 - which is considered to be the best value for money compared to other vaccination strategies - requires an additional 380 FTEs for general practitioners, 602 FTEs for nurses, and 205 FTEs for midwives; it can reduce the number of FTEs for medical social workers, paediatricians, infectious disease specialists, neurologists, anaesthesiologists, radiologists, ultrasonologists, medical technologists, radiologic technologists, and pharmacists by 7, 17.9, 9.7, 0.4, 0.1, 0.7, 0.1, 12.3, 2, and 9.7, respectively, when compared to the no vaccination policy. This is the first attempt to estimate the impact of HRH alongside a model-based economic evaluation study, which can be eventually applied to other vaccine studies, especially those which inform resource allocation in developing settings where not only financial resources but also HRH are

  15. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... SESAP Sampler SRGS Resources in Surgical Education ACS Fundamentals of Surgery Curriculum Mastery in General Surgery Program ... Communications to the Profession Advocacy Advocacy Overview Quality Payment Program QPP Resource Center QPP Resource Center 2018 ...

  16. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... You Want to Be a Surgeon Resident Resources Teaching Resources Online Guide to Choosing a Surgical Residency ... Research Findings Quality Program Initiatives Communications to the Profession Advocacy Advocacy Overview Quality Payment Program QPP Resource ...

  17. Production and characterization of H3BO3-Li2CO3-K2CO3-MgO for dosimetry

    International Nuclear Information System (INIS)

    Marini, Andrea; Ciolini, Riccardo; Souza, Susana O.; Valenca, Joao V.B.; Oliveira, Raquel A.P.; D'Enrrico, Francesco

    2014-01-01

    This work examines a borate glass produced with oxides of potassium and lithium, known as LKB. The suitability of borate glasses for thermoluminescent (TL) dosimetry has been reported in previous studies. In particular, borate glasses doped with different elements showed good characteristics in terms of linearity, sensitivity and effective atomic number. However, borate glasses are also known to have high hygroscopicity, which can reduce the sensitivity of a dosimeter. Contrary to previous studies, in this work, Mg was used as one of the main components of the glass composition. Mg is known to improve the stability of the glass, since it reduces the mobility of the alkali ions and can thus reduce the hygroscopicity of the LKB glass. Three compositions containing 0, 5 and 11 mol% of magnesium oxide were examined in order to determine the effect of magnesium specifically on luminescence, high-temperature resistance and hygroscopicity of LKB glass. The LKB glass with 11 mol% of Mg showed favorable characteristics for the production of dosimeters

  18. Cockpit resource management training at People Express

    Science.gov (United States)

    Bruce, Keith D.; Jensen, Doug

    1987-01-01

    In January 1986 in a continuing effort to maintain and improve flight safety and solve some Cockpit Resource Management (CRM) problems, People Express implemented a new CRM training program. It is a continuously running program, scheduled over the next three years and includes state-of-the-art full-mission simulation (LOFT), semi-annual seminar workshops and a comprehensive academic program authored by Robert W. Mudge of Cockpit Management Resources Inc. That program is outlined and to maximize its contribution to the workshop's goals, is organized into four topic areas: (1) Program content: the essential elements of resource management training; (2) Training methods: the strengths and weaknesses of current approaches; (3) Implementation: the implementation of CRM training; and (4) Effectiveness: the effectiveness of training. It is confined as much as possible to concise descriptions of the program's basic components. Brief discussions of rationale are included, however no attempt is made to discuss or review popular CRM tenets or the supporting research.

  19. Projections of costs, financing, and additional resource requirements for low- and lower middle-income country immunization programs over the decade, 2011-2020.

    Science.gov (United States)

    Gandhi, Gian; Lydon, Patrick; Cornejo, Santiago; Brenzel, Logan; Wrobel, Sandra; Chang, Hugh

    2013-04-18

    The Decade of Vaccines Global Vaccine Action Plan has outlined a set of ambitious goals to broaden the impact and reach of immunization across the globe. A projections exercise has been undertaken to assess the costs, financing availability, and additional resource requirements to achieve these goals through the delivery of vaccines against 19 diseases across 94 low- and middle-income countries for the period 2011-2020. The exercise draws upon data from existing published and unpublished global forecasts, country immunization plans, and costing studies. A combination of an ingredients-based approach and use of approximations based on past spending has been used to generate vaccine and non-vaccine delivery costs for routine programs, as well as supplementary immunization activities (SIAs). Financing projections focused primarily on support from governments and the GAVI Alliance. Cost and financing projections are presented in constant 2010 US dollars (US$). Cumulative total costs for the decade are projected to be US$57.5 billion, with 85% for routine programs and the remaining 15% for SIAs. Delivery costs account for 54% of total cumulative costs, and vaccine costs make up the remainder. A conservative estimate of total financing for immunization programs is projected to be $34.3 billion over the decade, with country governments financing 65%. These projections imply a cumulative funding gap of $23.2 billion. About 57% of the total resources required to close the funding gap are needed just to maintain existing programs and scale up other currently available vaccines (i.e., before adding in the additional costs of vaccines still in development). Efforts to mobilize additional resources, manage program costs, and establish mutual accountability between countries and development partners will all be necessary to ensure the goals of the Decade of Vaccines are achieved. Establishing or building on existing mechanisms to more comprehensively track resources and

  20. California's forest resources. Preliminary assessment

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    This Preliminary Assessment was prepared in response to the California Forest Resources Assessment and Policy Act of 1977 (FRAPA). This Act was passed to improve the information base upon which State resource administrators formulate forest policy. The Act provides for this report and a full assessment by 1987 and at five year intervals thereafter. Information is presented under the following chapter titles: introduction to the forest resources assessment program; the forest area: a general description; classifications of the forest lands; the watersheds; forest lands and the air resource; fish and wildlife resources; the forested rangelands; the wilderness; forest lands as a recreation resource; the timber resource; wood energy; forest lands and the mineral, fossil fuels, and geothermal energy resources; mathematically modeling California's forest lands; vegetation mapping using remote sensing technology; important forest resources legislation; and, State and cooperative State/Federal forestry programs. Twelve indexes, a bibliography, and glossary are included. (JGB)

  1. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Policy Updates Selected Research Findings Quality Program Initiatives Communications to the Profession Advocacy Advocacy Overview Quality Payment Program QPP Resource Center QPP Resource Center 2018 Information 2017 Information Program Rules Surgeon Specific Registry Metabolic ...

  2. Long Term Resource Monitoring Program Annual Status Report, 1999: Macroinvertebrate Sampling in Six Reaches of the Upper Mississippi River System

    National Research Council Canada - National Science Library

    Sauer, Jennifer

    2000-01-01

    In 1992, macroinvertebrate sampling was initiated in Pools 4, 8, 13, 26, and the Open River reach of the Mississippi River, and La Orange Pool of the Illinois River as part of the Long Term Resource Monitoring Program...

  3. Science requirements for free-flying imaging radar (FIREX) experiment for sea ice, renewable resources, nonrenewable resources and oceanography

    Science.gov (United States)

    Carsey, F.

    1982-01-01

    A future bilateral SAR program was studied. The requirements supporting a SAR mission posed by science and operations in sea-ice-covered waters, oceanography, renewable resources, and nonrenewable resources are addressed. The instrument, mission, and program parameters were discussed. Research investigations supporting a SAR flight and the subsequent overall mission requirements and tradeoffs are summarized.

  4. Four Generations of Maintenance Resource Management Programs in the United States: An Analysis of the Past, Present, and Future

    Science.gov (United States)

    Taylor, James C.; Patankar, Manoj S.

    2001-01-01

    This paper analyzes four generations of Maintenance Resource Management (MRM) programs implemented by aviation maintenance organizations in the United States. Data collected from over ten years of survey research and field observations are used for this analysis; they are presented in a case-study format. The first three generations of MRM programs were episodic efforts to increase safety through teamwork, focus group discussions, and awareness courses, respectively. Now, the fourth generation programs, characterized by a commitment to long-term communication and behavioral changes in maintenance, are set to build on those earlier generations, toward a culture of mutual trust between mechanics, their managers, and regulators.

  5. From local strains to specific starters: the process structuring a research program on the activation and management of a biotechnological resource

    OpenAIRE

    Casalta, Erick; Bona, Pascale

    2009-01-01

    This study presents a research-action program carried out in Corsica with a group of cheese makers to develop specific starters. Based on the direct participation of the cheese makers, this study consisted in designing starters with lactic acid bacterial strains isolated from milks and cheeses of this group of cheese makers. This process modified an individually and empirically used resource, local strains, into a shared and collectively managed resource, specific starters. Patrimonial featur...

  6. Evaluation of the Waste Tire Resources Recovery Program and Environmental Health Policy in Taiwan

    Directory of Open Access Journals (Sweden)

    Chia-Ching Chen

    2009-03-01

    Full Text Available This paper examines the effectiveness of Taiwanese environmental health policies, whose aim is to improve environmental quality by reducing tire waste via the Tire Resource Recovery Program. The results confirm that implemented environmental health policies improve the overall health of the population (i.e. a decrease in death caused by bronchitis and other respiratory diseases. Current policy expenditures are far below the optimal level, as it is estimated that a ten percent increase in the subsidy would decrease the number of deaths caused by bronchitis and other respiratory diseases by 0.58% per county/city per year on average.

  7. Overview of the National Uranium Resource Evaluation Hydrogeochemical and Stream Sediment Reconnaissance Program

    International Nuclear Information System (INIS)

    Bolivar, S.L.

    1980-01-01

    A Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) for uranium is currently being conducted throughout the conterminous United States and Alaska. The HSSR is part of the National Uranium Resource Evaluation sponsored by the US Department of Energy. This ambitious geochemical reconnaissance program is conducted by four Department of Energy laboratories: Los Alamos Scientific Laboratory, Lawrence Livermore Laboratory, Oak Ridge Gaseous Diffusion Plant, and Savannah River Laboratory. The program is based on an extensive review of world literature, reconnaissance work done in other countries, and pilot studies conducted by each laboratory. Sample-collection methods and sample density are determined to optimize the probability of detecting potential uranium mineralization. To achieve this aim, each laboratory has developed independent standardized field collection procedures that are designed for its section of the country. Field parameters such as pH, conductivity, climate, geography, and geology are recorded at each site. Most areas are sampled at densities of one sample site per 10 to 23 km 2 . The HSSR program has helped to improve existing hydrogeochemical reconnaissance exploration techniques. In addition to providing industry with data that may help to identify potential uranium districts and to extend known uranium provinces, the HSSR also provides multielement analytical data that can be used in water quality, soil, sediment, environmental, and base-metal exploration studies

  8. Overview of the National Uranium Resource Evaluation Hydrogeochemical and Stream Sediment Reconnaissance Program

    International Nuclear Information System (INIS)

    Bolivar, S.L.

    1980-07-01

    A Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) for uranium is currently being conducted throughout the conterminous United States and Alaska. The HSSR is part of the National Uranium Resource Evaluation sponsored by the US Department of Energy. This ambitious geochemical reconnasissance program is conducted by four Department of Energy Laboratories: Los Alamos Scientific Laboratory, Lawrence Livermore Laboratory, Oak Ridge Gaseous Diffusion Plant, and Savannah River Laboratory. Each laboratory was assigned a geographic region of the United States. The program is based on an extensive review of world literature, reconnaissance work done in other countries, and pilot studies conducted by each laboratory. Sample-collection methods and sample density are determined to optimize the probability of detecting potential uranium mineralization. To achieve this aim, each laboratory has developed independent standardized field collection procedures that are designed for its section of the country. Field parameters such as pH, conductivity, climate, geography, and geology are recorded at each site. Most areas are sampled at densities of one sample site per 10 to 23 km 2 . The HSSR program has helped to improve existing hydrogeochemical reconnaissance exploration techniques. In addition to providing industry with data that may help to identify potential uranium districts and to extend known uranium provinces, the HSSR also provides multielement analytical data that can be used in water quality, soil, sediment, environmental, and base-metal exploration studies

  9. Using discrete-time mathematical programming to optimise the extraction rate of a durable non-renewable resource with a single primary supplier

    Directory of Open Access Journals (Sweden)

    Albert Corominas

    Full Text Available A non-linear discrete-time mathematical program model is proposed to determining the optimal extraction policy for a single primary supplier of a durable non-renewable resource, such as gemstones or some metals. Karush, Kuhn and Tucker conditions allow obtaining analytic solutions and general properties of them in some specific settings. Moreover, provided that the objective function (i.e., the discounted value of the incomes throughout the planning horizon is concave, the model can be easily solved, even using standard commercial solver. However, the analysis of the solutions obtained for different assumptions of the values of the parameters show that the optimal extraction policies and the corresponding prices do not exhibit a general shape. Keywords: Durable non-renewable resources, Single primary supplier, Non-linear programming

  10. Cinnamon Extract Enhances Glucose Uptake in 3T3-L1 Adipocytes and C2C12 Myocytes by Inducing LKB1-AMP-Activated Protein Kinase Signaling

    Science.gov (United States)

    Shen, Yan; Honma, Natsumi; Kobayashi, Katsuya; Jia, Liu Nan; Hosono, Takashi; Shindo, Kazutoshi; Ariga, Toyohiko; Seki, Taiichiro

    2014-01-01

    We previously demonstrated that cinnamon extract (CE) ameliorates type 1 diabetes induced by streptozotocin in rats through the up-regulation of glucose transporter 4 (GLUT4) translocation in both muscle and adipose tissues. This present study was aimed at clarifying the detailed mechanism(s) with which CE increases the glucose uptake in vivo and in cell culture systems using 3T3-L1 adipocytes and C2C12 myotubes in vitro. Specific inhibitors of key enzymes in insulin signaling and AMP-activated protein kinase (AMPK) signaling pathways, as well as small interference RNA, were used to examine the role of these kinases in the CE-induced glucose uptake. The results showed that CE stimulated the phosphorylation of AMPK and acetyl-CoA carboxylase. An AMPK inhibitor and LKB1 siRNA blocked the CE-induced glucose uptake. We also found for the first time that insulin suppressed AMPK activation in the adipocyte. To investigate the effect of CE on type 2 diabetes in vivo, we further performed oral glucose tolerance tests and insulin tolerance tests in type 2 diabetes model rats administered with CE. The CE improved glucose tolerance in oral glucose tolerance tests, but not insulin sensitivity in insulin tolerance test. In summary, these results indicate that CE ameliorates type 2 diabetes by inducing GLUT4 translocation via the AMPK signaling pathway. We also found insulin antagonistically regulates the activation of AMPK. PMID:24551069

  11. Stochastic dynamic programming model for optimal resource ...

    Indian Academy of Sciences (India)

    M Bhuvaneswari

    2018-04-11

    Apr 11, 2018 ... handover in VANET; because of high dynamics in net- work topology, collaboration ... containers, doctors, nurses, cash and stocks. Similarly, ... GTBA does not take the resource types and availability into consideration.

  12. C. elegans STRADalpha and SAD cooperatively regulate neuronal polarity and synaptic organization.

    Science.gov (United States)

    Kim, Joanne S M; Hung, Wesley; Narbonne, Patrick; Roy, Richard; Zhen, Mei

    2010-01-01

    Neurons are polarized cells with morphologically and functionally distinct axons and dendrites. The SAD kinases are crucial for establishing the axon-dendrite identity across species. Previous studies suggest that a tumour suppressor kinase, LKB1, in the presence of a pseudokinase, STRADalpha, initiates axonal differentiation and growth through activating the SAD kinases in vertebrate neurons. STRADalpha was implicated in the localization, stabilization and activation of LKB1 in various cell culture studies. Its in vivo functions, however, have not been examined. In our present study, we analyzed the neuronal phenotypes of the first loss-of-function mutants for STRADalpha and examined their genetic interactions with LKB1 and SAD in C. elegans. Unexpectedly, only the C. elegans STRADalpha, STRD-1, functions exclusively through the SAD kinase, SAD-1, to regulate neuronal polarity and synaptic organization. Moreover, STRD-1 tightly associates with SAD-1 to coordinate its synaptic localizations. By contrast, the C. elegans LKB1, PAR-4, also functions in an additional genetic pathway independently of SAD-1 and STRD-1 to regulate neuronal polarity. We propose that STRD-1 establishes neuronal polarity and organizes synaptic proteins in a complex with the SAD-1 kinase. Our findings suggest that instead of a single, linear genetic pathway, STRADalpha and LKB1 regulate neuronal development through multiple effectors that are shared in some cellular contexts but distinct in others.

  13. Remote Assessment of Lunar Resource Potential

    Science.gov (United States)

    Taylor, G. Jeffrey

    1992-01-01

    Assessing the resource potential of the lunar surface requires a well-planned program to determine the chemical and mineralogical composition of the Moon's surface at a range of scales. The exploration program must include remote sensing measurements (from both Earth's surface and lunar orbit), robotic in situ analysis of specific places, and eventually, human field work by trained geologists. Remote sensing data is discussed. Resource assessment requires some idea of what resources will be needed. Studies thus far have concentrated on oxygen and hydrogen production for propellant and life support, He-3 for export as fuel for nuclear fusion reactors, and use of bulk regolith for shielding and construction materials. The measurement requirements for assessing these resources are given and discussed briefly.

  14. Genomic resources in mungbean for future breeding programs

    Directory of Open Access Journals (Sweden)

    Sue K Kim

    2015-08-01

    Full Text Available Among the legume family, mungbean (Vigna radiata has become one of the important crops in Asia, showing a steady increase in global production. It provides a good source of protein and contains most notably folate and iron. Beyond the nutritional value of mungbean, certain features make it a well-suited model organism among legume plants because of its small genome size, short life-cycle, self-pollinating, and close genetic relationship to other legumes. In the past, there have been several efforts to develop molecular markers and linkage maps associated with agronomic traits for the genetic improvement of mungbean and, ultimately, breeding for cultivar development to increase the average yields of mungbean. The recent release of a reference genome of the cultivated mungbean (V. radiata var. radiata VC1973A and an additional de novo sequencing of a wild relative mungbean (V. radiata var. sublobata has provided a framework for mungbean genetic and genome research, that can further be used for genome-wide association and functional studies to identify genes related to specific agronomic traits. Moreover, the diverse gene pool of wild mungbean comprises valuable genetic resources of beneficial genes that may be helpful in widening the genetic diversity of cultivated mungbean. This review paper covers the research progress on molecular and genomics approaches and the current status of breeding programs that have developed to move toward the ultimate goal of mungbean improvement.

  15. Savannah River Laboratory semiannual report, April-September 1979. Hydrogeochemical and stream sediment reconnaissance: National Uranium Resource Evaluation Program

    International Nuclear Information System (INIS)

    1979-10-01

    This report summarizes the accomplishments, status, and program of the Savannah River Laboratory (SRL) contribution to the National Uranium Resource Evaluation (NURE) program. SRL has accepted responsibility for Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) of 1,500,000 square miles in 30 eastern and 7 far-western states. The report is a progress report covering the period April 1979 through September 1979. SRL efforts in the following areas are discussed: reconnaissance and detailed studies in geological programs; management, analysis, and interpretation of analytical and field data; reporting of HSSR results; sample preparation methods; and neutron activation analysis and other analytical techniques. Appendix A to the report summarizes the SRL-NURE production of the April 1979-September 1979 period and the program plans for the first half of FY-1980. Page-scale maps are included that show the status of completed sampling, analysis, and data reports placed on open file

  16. Classroom Resources | Argonne National Laboratory

    Science.gov (United States)

    Center Community Outreach Learning Experiences School Competitions Teacher Programs Classroom Resources Learning Center Community Outreach Learning Experiences School Competitions Teacher Programs Classroom every student and that is free from harassment and discrimination based upon race, color, religion

  17. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1995

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, M.J.; Brooks, R.D.; Sassaman, K.E.; Crass, D.C. [and others

    1995-10-01

    The Savannah River Archaeological Research Program (SRARP) continued through FY95 with the United States Department of Energy to fulfill a threefold mission of cultural resource management, research, and public education at the Savannah River Site. Over 2,300 acres of land on the SRS came under cultural resources review in FY95. This activity entailed 30 field surveys, resulting in the recording of 86 new sites. Twenty-two existing sites within survey tract boundaries were revisited to update site file records. Research conducted by SRARP was reported in 11 papers and monographs published during FY95. SRARP staff also presented research results in 18 papers at professional meetings. Field research included several testing programs, excavations, and remote sensing at area sites, as well as data collection abroad. Seven grants were acquired by SRARP staff to support off-site research. In the area of heritage education, the SRARP expanded its activities in FY95 with a full schedule of classroom education, public outreach, and on-site tours. Volunteer excavations at the Tinker Creek site were continued with the Augusta Archaeological Society and other avocational groups, and other off-site excavations provided a variety of opportunities for field experience. Some 80 presentations, displays and tours were provided for schools, historical societies, civic groups, and environmental and historical awareness day celebrations. Additionally, SRARP staff taught four anthropology courses at area colleges.

  18. A Cost-Effectiveness Evaluation Approach to Improving Resource Allocations for School Systems. Administering for Change Program. A Professional Paper.

    Science.gov (United States)

    Temkin, Sanford

    This dissertation begins with a description of some methods employed in making public-sector resource-allocation decisions, with conclusions on the appropriateness of each method for evaluating the ongoing programs of a school system. The second section has been rewritten and published as "A Comprehensive Theory of Cost-Effectiveness" (EA 002…

  19. Negative regulation of AMP-activated protein kinase (AMPK) activity by macrophage migration inhibitory factor (MIF) family members in non-small cell lung carcinomas.

    Science.gov (United States)

    Brock, Stephanie E; Rendon, Beatriz E; Yaddanapudi, Kavitha; Mitchell, Robert A

    2012-11-02

    AMP-activated protein kinase (AMPK) is a nutrient- and metabolic stress-sensing enzyme activated by the tumor suppressor kinase, LKB1. Because macrophage migration inhibitory factor (MIF) and its functional homolog, d-dopachrome tautomerase (d-DT), have protumorigenic functions in non-small cell lung carcinomas (NSCLCs) but have AMPK-activating properties in nonmalignant cell types, we set out to investigate this apparent paradox. Our data now suggest that, in contrast to MIF and d-DTs AMPK-activating properties in nontransformed cells, MIF and d-DT act cooperatively to inhibit steady-state phosphorylation and activation of AMPK in LKB1 wild type and LKB1 mutant human NSCLC cell lines. Our data further indicate that MIF and d-DT, acting through their shared cell surface receptor, CD74, antagonize NSCLC AMPK activation by maintaining glucose uptake, ATP production, and redox balance, resulting in reduced Ca(2+)/calmodulin-dependent kinase kinase β-dependent AMPK activation. Combined, these studies indicate that MIF and d-DT cooperate to inhibit AMPK activation in an LKB1-independent manner.

  20. Community Resources for Career Education: Starring Baltimore's McCormick Plan

    Science.gov (United States)

    Carey, E. Niel; Marshall, Howard E.

    1973-01-01

    The article develops from a general discussion of the utilization of community resources in career education to a discussion of a particular program--the McCormick Plan in Baltimore--and other Maryland programs. Suggestions drawn from those programs are offered for identifying and using such resources. (AG)

  1. A Program for the Preparation and Certification of School Administrators. Program E--Learning Resource Specialist. In Compliance with Guidelines and Standards for the Development and Approval of Programs of Preparation Leading to Certification [of] School Professional Personnel.

    Science.gov (United States)

    Canzler, Lillian

    The initial and continuing competencies needed by a district-level administrator in educational media or learning resources are outlined. An introductory discussion covers internship program procedures, supervision and evaluation, record keeping and reports, and competencies and skills. Competencies are then defined, the use of the format is…

  2. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Quality Standard Optimal Resources for Surgical Quality and Safety Inspiring Quality Initiative Resources Continuous Quality Improvement ACS Clinical Scholars in Residence AHRQ Safety Program for ISCR AHRQ Safety Program for ISCR ...

  3. NASA's Applied Sciences for Water Resources

    Science.gov (United States)

    Doorn, Bradley; Toll, David; Engman, Ted

    2011-01-01

    The Earth Systems Division within NASA has the primary responsibility for the Earth Science Applied Science Program and the objective to accelerate the use of NASA science results in applications to help solve problems important to society and the economy. The primary goal of the Earth Science Applied Science Program is to improve future and current operational systems by infusing them with scientific knowledge of the Earth system gained through space-based observation, assimilation of new observations, and development and deployment of enabling technologies, systems, and capabilities. This paper discusses one of the major problems facing water resources managers, that of having timely and accurate data to drive their decision support tools. It then describes how NASA?s science and space based satellites may be used to overcome this problem. Opportunities for the water resources community to participate in NASA?s Water Resources Applications Program are described.

  4. Human resources FY 1995 Site Program Plan WBS 6.10.2

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    This document contains information concerning human resources management at the Hanford Reservation. Information discusses the following topics: Cost estimates, closure and placement of labor resources, and management of human resources throughout the Hanford Site.

  5. Promoting Physical Activity within Under-Resourced Afterschool Programs: A Qualitative Investigation of Staff Experiences and Motivational Strategies for Engaging Youth

    Science.gov (United States)

    Zarrett, Nicole; Abraczinskas, Michelle; Skiles Cook, Brittany; Wilson, Dawn K.; Ragaban, Faten

    2018-01-01

    Afterschool programs (ASPs) have become increasingly recognized as a key context to support youth daily physical activity (PA) accrual. Using Self-Determination Theory (SDT) as a framework, this study examined staff perspectives on the strengths and barriers within under-resourced ASPs for establishing a social-motivational climate for encouraging…

  6. Thyroid hormone activates rat liver adenosine 5,-monophosphate-activated protein kinase: relation to CaMKKb, TAK1 and LKB1 expression and energy status.

    Science.gov (United States)

    Vargas, R; Ortega, Y; Bozo, V; Andrade, M; Minuzzi, G; Cornejo, P; Fernandez, V; Videla, L A

    2013-01-01

    AMP-activated protein kinase (AMPK) is a sensor of energy status supporting cellular energy homeostasis that may represent the metabolic basis for 3,3,,5-triiodo-L-thyronine (T3) liver preconditioning. Functionally transient hyperthyroid state induced by T3 (single dose of 0.1 mg/kg) in fed rats led to upregulation of mRNA expression (RT-PCR) and protein phosphorylation (Western blot) of hepatic AMPK at 8 to 36 h after treatment. AMPK Thr 172 phosphorylation induced by T3 is associated with enhanced mRNA expression of the upstream kinases Ca2+ -calmodulin-dependent protein kinase kinase-beta (CaMKKbeta) and transforming growth-factor-beta-activated kinase-1 (TAK1), with increased protein levels of CaMKKbeta and higher TAK1 phosphorylation, without changes in those of the liver kinase B1 (LKB1) signaling pathway. Liver contents of AMP and ADP were augmented by 291 percent and 44 percent by T3 compared to control values (p less than 0.05), respectively, whereas those of ATP decreased by 64% (p less than 0.05), with no significant changes in the total content of adenine nucleotides (AMP + ADP + ATP) at 24 h after T3 administration. Consequently, hepatic ATP/ADP content ratios exhibited 64 percent diminution (p less than 0.05) and those of AMP/ATP increased by 425 percent (p less than 0.05) in T3-treated rats over controls. It is concluded that in vivoT3 administration triggers liver AMPK upregulation in association with significant enhancements in AMPK mRNA expression, AMPK phosphorylation coupled to CaMKKbeta and TAK1 activation, and in AMP/ATP ratios, which may promote enhanced AMPK activity to support T3-induced energy consuming processes such as those of liver preconditioning.

  7. Computer Resources | College of Engineering & Applied Science

    Science.gov (United States)

    Engineering Concentration on Ergonomics M.S. Program in Computer Science Interdisciplinary Concentration on Structural Engineering Laboratory Water Resources Laboratory Computer Science Department Computer Science Academic Programs Computer Science Undergraduate Programs Computer Science Major Computer Science Tracks

  8. Findings of an evaluation of public involvement programs associated with the development of a Land and Resource Management Plan for the Ouachita National Forest

    Energy Technology Data Exchange (ETDEWEB)

    Holthoff, M.G. [Pacific Northwest Lab., Richland, WA (United States); Howell, R.E. [Washington State Univ., Pullman, WA (United States)

    1993-08-01

    Federal regulations require the United States Forest Service (USFS) to integrate public input and values into decisions concerning land and resource management planning. The USFS has typically relied on traditional methods of involving the public, whereby public access and input to policy development are unilaterally controlled by the agency. Because of the highly political nature of land and resource management planning, such technocratic forms of public involvement and decision-making appear to be proving ineffective. This paper describes and evaluates two public involvement programs associated with the Ouachita National Forest`s (ONF) lengthy forest planning process. The research consisted of personal interviews with key program leaders and knowledgeable citizen participants, collection of secondary data, and a survey of citizen participants. Because of controversial planning decisions made during an initial planning process, the ONF was forced to re-enter the planning process in order to address unresolved planning issues and to conduct a more effective public involvement program. The supplemental planning process also resulted in a considerable degree of public contention. The survey revealed that although citizen participants were somewhat more satisfied with the supplemental public involvement program relative to the initial program, neither program was viewed as satisfactory. The findings of the study suggest that in order to be more effective, USFS public involvement programs should be more responsive to public concerns and conducted in adherence to principles of collaborative planning.

  9. An interactive computer approach to performing resource analysis for a multi-resource/multi-project problem. [Spacelab inventory procurement planning

    Science.gov (United States)

    Schlagheck, R. A.

    1977-01-01

    New planning techniques and supporting computer tools are needed for the optimization of resources and costs for space transportation and payload systems. Heavy emphasis on cost effective utilization of resources has caused NASA program planners to look at the impact of various independent variables that affect procurement buying. A description is presented of a category of resource planning which deals with Spacelab inventory procurement analysis. Spacelab is a joint payload project between NASA and the European Space Agency and will be flown aboard the Space Shuttle starting in 1980. In order to respond rapidly to the various procurement planning exercises, a system was built that could perform resource analysis in a quick and efficient manner. This system is known as the Interactive Resource Utilization Program (IRUP). Attention is given to aspects of problem definition, an IRUP system description, questions of data base entry, the approach used for project scheduling, and problems of resource allocation.

  10. 30 CFR 779.21 - Soil resources information.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Soil resources information. 779.21 Section 779.21 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SURFACE COAL MINING AND RECLAMATION OPERATIONS PERMITS AND COAL EXPLORATION SYSTEMS UNDER REGULATORY PROGRAMS SURFACE MINING PERMIT...

  11. Employee assistance programs: history and program description.

    Science.gov (United States)

    Gilbert, B

    1994-10-01

    1. The history and development of Employee Assistance Programs (EAPs) can be traced back to the 1800s. There are currently over 10,000 EAPs in the United States. 2. Standards for program accreditation and counselor certification have been established for EAPs. The "core technology of Employee Assistance Programs" includes identification of behavioural problems based on job performance issues, expert consultation with supervisors, appropriate use of constructive confrontation, microlinkages with treatment providers and resources, macrolinkages between providers, resources, and work organizations, focus on substance abuse, and evaluation of employee success based on job performance. 3. Some EAPs take a broad brush approach, and incorporate health promotion and managed care functions.

  12. Diabetes HealthSense: Resources for Living Well

    Medline Plus

    Full Text Available ... E-MAIL UPDATES External Link Disclaimer National Diabetes Education Program HealthSense Home Make a Plan Articles About ... 65+) Type of Resource Select one: Printable documents Online programs In-person programs Videos and podcasts Presentations ...

  13. Mozambique field epidemiology and laboratory training program: a pathway for strengthening human resources in applied epidemiology.

    Science.gov (United States)

    Baltazar, Cynthia Semá; Taibo, Cátia; Sacarlal, Jahit; Gujral, Lorna; Salomão, Cristolde; Doyle, Timothy

    2017-01-01

    In the last decades, Mozambique has been undergoing demographic, epidemiological, economic and social transitions, which have all had a notable impact on the National Health System. New challenges have emerged, causing a need to expand the preparation and response to emerging disease threats and public health emergencies. We describe the structure and function of the Mozambique Field Epidemiology Training Program (MZ-FELTP) and the main outputs achieved during the first 6 years of program implementation (consisting of 3 cohorts). We also outline the contribution of the program to the National Health System and assess the retention of the graduates. The MZ-FELTP is a post-graduate in-service training program, based on the acquisition of skills, within two tracks: applied epidemiology and laboratory management. The program was established in 2010, with the objective of strengthening capacity in applied epidemiology and laboratory management, so that events of public health importance can be detected and investigated in a timely and effective manner. The program is in its seventh year, having successfully trained 36 health professionals in the advanced course. During the first six years of the program, more than 40 outbreaks were investigated, 37 surveillance system evaluations were conducted and 39 descriptive data analyses were performed. Surveillance activities were implemented for mass events and emergency situations. In addition, more than 100 oral and poster presentations were given by trainees at national and international conferences. The MZ-FELTP has helped provide the Ministry of Health with the human and technical resources and operational capacity, to rapidly and effectively respond to major public health challenges in the country. The continuous involvement of key stakeholders is necessary for the continuation, expansion and ongoing sustainability of the program.

  14. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... About Quality Programs ACS Leadership in Quality ACS Leadership in Quality Setting the Quality Standard Optimal Resources for Surgical Quality and Safety Inspiring Quality Initiative Resources Continuous Quality Improvement ACS Clinical Scholars in Residence AHRQ Safety Program ...

  15. Mongolia wind resource assessment project

    International Nuclear Information System (INIS)

    Elliott, D.; Chadraa, B.; Natsagdorj, L.

    1998-01-01

    The development of detailed, regional wind-resource distributions and other pertinent wind resource characteristics (e.g., assessment maps and reliable estimates of seasonal, diurnal, and directional) is an important step in planning and accelerating the deployment of wind energy systems. This paper summarizes the approach and methods being used to conduct a wind energy resource assessment of Mongolia. The primary goals of this project are to develop a comprehensive wind energy resource atlas of Mongolia and to establish a wind measurement program in specific regions of Mongolia to identify prospective sites for wind energy projects and to help validate some of the wind resource estimates. The Mongolian wind resource atlas will include detailed, computerized wind power maps and other valuable wind resource characteristic information for the different regions of Mongolia

  16. 30 CFR 783.21 - Soil resources information.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Soil resources information. 783.21 Section 783.21 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SURFACE COAL MINING AND RECLAMATION OPERATIONS PERMITS AND COAL EXPLORATION SYSTEMS UNDER REGULATORY PROGRAMS UNDERGROUND MINING PERMIT APPLICATION...

  17. Childhood cancer survivorship educational resources in North American pediatric hematology/oncology fellowship training programs: a survey study.

    Science.gov (United States)

    Nathan, Paul C; Schiffman, Joshua D; Huang, Sujuan; Landier, Wendy; Bhatia, Smita; Eshelman-Kent, Debra; Wright, Jennifer; Oeffinger, Kevin C; Hudson, Melissa M

    2011-12-15

    Childhood cancer survivors require life-long care by clinicians with an understanding of the specific risks arising from the prior cancer and its therapy. We surveyed North American pediatric hematology/oncology training programs to evaluate their resources and capacity for educating medical trainees about survivorship. An Internet survey was sent to training program directors and long-term follow-up clinic (LTFU) directors at the 56 US and Canadian centers with pediatric hematology/oncology fellowship programs. Perceptions regarding barriers to and optimal methods of delivering survivorship education were compared among training program and LTFU clinic directors. Responses were received from 45/56 institutions of which 37/45 (82%) programs require that pediatric hematology/oncology fellows complete a mandatory rotation focused on survivorship. The rotation is 4 weeks or less in 21 programs. Most (36/45; 80%) offer didactic lectures on survivorship as part of their training curriculum, and these are considered mandatory for pediatric hematology/oncology fellows at 26/36 (72.2%). Only 10 programs (22%) provide training to medical specialty trainees other than pediatric hematology/oncology fellows. Respondents identified lack of time for trainees to spend learning about late effects as the most significant barrier to providing survivorship teaching. LTFU clinic directors were more likely than training program directors to identify lack of interest in survivorship among trainees and survivorship not being a formal or expected part of the fellowship training program as barriers. The results of this survey highlight the need to establish standard training requirements to promote the achievement of basic survivorship competencies by pediatric hematology/oncology fellows. Copyright © 2011 Wiley Periodicals, Inc.

  18. 77 FR 4581 - Alaska Region's Subsistence Resource Commission (SRC) Program

    Science.gov (United States)

    2012-01-30

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-AKR-LACL; 9924-PYS] Alaska Region's... public meeting for the National Park Service (NPS) Alaska Region's Subsistence Resource Commission (SRC... Meeting Debora R. Cooper, Associate Regional Director, Resources and Subsistence, Alaska Region. [FR Doc...

  19. The American Association of Occupational Health Nurses' Respiratory Protection Education Program and Resources Webkit for Occupational Health Professionals.

    Science.gov (United States)

    Pompeii, Lisa; Byrd, Annette; Delclos, George L; Conway, Sadie H

    2016-12-01

    Organizations are required to adhere to the Occupational Safety and Health Administration's (OSHA) Respiratory Protection Standard (29 CFR 1910.134) if they have workers that wear a respirator on the job. They must also have an employee "suitably trained" to administer their program. The National Institute for Occupational Safety and Health and its National Personal Protective Technology Laboratory have worked to champion the occupational health nurse in this role by collaborating with the American Association of Occupational Health Nurses to develop free, online respiratory protection training and resources (RPP Webkit). This article describes the development, content, and success of this training. To date, 724 participants have completed the training, 32.6% of whom lead their organization's respiratory protection program, 15.3% who indicated they will lead a program in the near future, and 52% who did not lead a program, but indicated that the training was relevant to their work. The majority "strongly agreed" the training was applicable to their work and it enhanced their professional expertise. © 2016 The Author(s).

  20. [Food and nutrition security policy in Brazil: an analysis of resource allocation].

    Science.gov (United States)

    Custódio, Marta Battaglia; Yuba, Tânia Yuka; Cyrillo, Denise Cavallini

    2013-02-01

    To describe the progression and distribution of federal funds for programs and activities that fall within the scope of the guidelines of the Brazilian National Policy on Food and Nutrition Security (PNSAN) in the period from 2004 to 2010. This descriptive study used data from the Transparency Website maintained by the Brazilian Public Sector Internal Control Office. Search results were exported to Excel spreadsheets. To determine the resources allocated to food security initiatives, a database was set up containing all actions developed by the federal government between 2004 and 2010. This database was reviewed and the actions that were not related to PNSAN were discarded. The annual amounts obtained were corrected by the Consumer Price Index and updated for the year 2010. Since actions are part of specific programs, the sum of the resources allocated for all the actions of a program amounted to the resources invested in the program as a whole. The programs were then prioritized according to the amount of resources received in 2010. Of the 5 014 actions receiving federal funds in the study period, 814 were related to PNSAN (229 programs). There was growth in resources allocated for PNSAN programs, reaching US$ 15 billion in 2010 (an 82% increase over the previous year). The largest amount was invested in Bolsa Família, a cash transfer program. Ten programs received 90% of the funds, of which five were linked to food production processes. The amount of resources invested in the PNSAN and in actions and programs that promote food and nutrition security is increasing in Brazil.

  1. 77 FR 4579 - Alaska Region's Subsistence Resource Commission (SRC) Program

    Science.gov (United States)

    2012-01-30

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-AKR-DENA; 9924-PYS] Alaska Region's... public meeting for the National Park Service (NPS) Alaska Region's Subsistence Resource Commission (SRC..., Associate Regional Director, Resources and Subsistence, Alaska Region. [FR Doc. 2012-1877 Filed 1-27-12; 8...

  2. Experience of health-system pharmacy administration residents in a longitudinal human resource management program.

    Science.gov (United States)

    Amerine, Lindsey B Poppe; Granko, Robert P; Savage, Scott W; Daniels, Rowell; Eckel, Stephen F

    2014-12-15

    The experience of health-system pharmacy administration (HSPA) residents in a longitudinal human resource (HR) management program is described. The subsequent benefits to the residents, department, and profession are also discussed. Postgraduate year 2 HSPA residents at an academic medical center desired more responsibility for managing an operational area. To this end, a program was created in which these residents directly manage a small group of pharmacy technicians and report to a clinical manager or assistant director with oversight responsibility. These "resident managers" are responsible, under the direction of the area's clinical manager, for the personnel, schedule, time and attendance, and HR activities of the area. Resident managers have led and sustained operational improvement projects in their areas. In addition to providing learning experiences to residents, the HSPA residency program has also improved the operations of the areas in which these residents work. Benefits to the residents include conducting annual performance evaluations for employees with whom they have a relationship as it is a task every administrator completes. Resident managers at UNC have consistently stated that this longitudinal HR experience is one of the most rewarding and most challenging experiences offered in the two-year HSPA residency. The involvement of HSPA residents in longitudinal management responsibilities furthers residents' leadership success by providing trained managers who are ready to immerse themselves into practice postresidency, having employee engagement and HR skills as well as experiences with leading operational improvements. A longitudinal HR management experience was successfully incorporated into an HSPA residency combined Master of Science degree program. Copyright © 2014 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  3. Evaluating participation in water resource management: A review

    Science.gov (United States)

    Carr, G.; BlöSchl, G.; Loucks, D. P.

    2012-11-01

    Key documents such as the European Water Framework Directive and the U.S. Clean Water Act state that public and stakeholder participation in water resource management is required. Participation aims to enhance resource management and involve individuals and groups in a democratic way. Evaluation of participatory programs and projects is necessary to assess whether these objectives are being achieved and to identify how participatory programs and projects can be improved. The different methods of evaluation can be classified into three groups: (i) process evaluation assesses the quality of participation process, for example, whether it is legitimate and promotes equal power between participants, (ii) intermediary outcome evaluation assesses the achievement of mainly nontangible outcomes, such as trust and communication, as well as short- to medium-term tangible outcomes, such as agreements and institutional change, and (iii) resource management outcome evaluation assesses the achievement of changes in resource management, such as water quality improvements. Process evaluation forms a major component of the literature but can rarely indicate whether a participation program improves water resource management. Resource management outcome evaluation is challenging because resource changes often emerge beyond the typical period covered by the evaluation and because changes cannot always be clearly related to participation activities. Intermediary outcome evaluation has been given less attention than process evaluation but can identify some real achievements and side benefits that emerge through participation. This review suggests that intermediary outcome evaluation should play a more important role in evaluating participation in water resource management.

  4. Assessment of the US Department of Energy's Sustainable Energy Resources for Consumers Grant Program

    Energy Technology Data Exchange (ETDEWEB)

    Lenahan, Tim [APPRISE, Inc., Princeton, NJ (United States); Bausch, Daniel [APPRISE, Inc., Princeton, NJ (United States); Carroll, David [APPRISE, Inc., Princeton, NJ (United States); Tonn, Bruce Edward [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Rose, Erin M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hawkins, Beth A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-10-01

    This report presents the results of an assessment of the Sustainable Energy Resources for Consumers (SERC) grant program that was administered by the US Department of Energy Weatherization and Intergovernmental Program Office. Grants totaling $90 million were awarded to 101 local weatherization agencies located in 27 states. More than 15,000 housing units were touched by the SERC program. Close to 29,000 SERC technologies were installed and/or services delivered. The report summarizes the results of site visits to 27 agencies in which the following 14 technologies were observed: solar photovoltaic panels, solar hot water heaters, solar thermal air panels for space heating, tankless water heaters, heat pump water heaters, geothermal heat pumps, super-evaporative cooling systems, combination boilers and indirect water heaters, small-scale residential wind systems, cool roofs, masonry spray foam insulation, attic radiant barriers, mini-split heat pumps, and in-home energy monitors. The evaluation found that the national weatherization network is capable of installing and delivering a wide range of new and innovative technologies, but the usability and adoptability of some technologies may prove impractical for the weatherization network and the demographic for which it serves.

  5. Final Report for the MANNRRSS II Program Management of Nevada's Natural Resources with Remote Sensing Systems, Beatty, NV

    Energy Technology Data Exchange (ETDEWEB)

    Lester Miller; Brian Horowitz; Chris Kratt; Tim Minor; Stephen F. Zitzer; James. V. Taranik; Zan L. Aslett; Todd O. Morken

    2009-06-04

    This document provides the Final Report on the Management of Nevada’s Natural Resources with Remote Sensing Systems (MANNRRSS) II program. This is a U.S. Department of Energy (DOE)-funded project tasked with utilizing hyperspectral and ancillary electro-optical instrumentation data to create an environmental characterization of an area directly adjacent to the Nevada Test Site (NTS).

  6. Hanford Site Biological Resources Mitigation Strategy

    International Nuclear Information System (INIS)

    Sackschewsky, Michael R

    2003-01-01

    The Biological Resources Mitigation Strategy (BRMiS), as part of a broader biological resource policy, is designed to aid the U.S. Department of Energy, Richland Operations Office (DOE-RL) in balancing its primary missions of waste cleanup, technology development, and economic diversification with its stewardship responsibilities for the biological resources it administers. This strategy will be applied to all DOE-RL programs as well as all contractor and subcontractor activities

  7. Gulf Coast geopressured-geothermal program summary report compilation. Volume 2-B: Resource description, program history, wells tested, university and company based research, site restoration

    Energy Technology Data Exchange (ETDEWEB)

    John, C.J.; Maciasz, G.; Harder, B.J.

    1998-06-01

    The US Department of Energy established a geopressured-geothermal energy program in the mid 1970`s as one response to America`s need to develop alternate energy resources in view of the increasing dependence on imported fossil fuel energy. This program continued for 17 years and approximately two hundred million dollars were expended for various types of research and well testing to thoroughly investigate this alternative energy source. This volume describes the following studies: Design well program; LaFourche Crossing; MG-T/DOE Amoco Fee No. 1 (Sweet Lake); Environmental monitoring at Sweet Lake; Air quality; Water quality; Microseismic monitoring; Subsidence; Dow/DOE L.R. Sweezy No. 1 well; Reservoir testing; Environmental monitoring at Parcperdue; Air monitoring; Water runoff; Groundwater; Microseismic events; Subsidence; Environmental consideration at site; Gladys McCall No. 1 well; Test results of Gladys McCall; Hydrocarbons in production gas and brine; Environmental monitoring at the Gladys McCall site; Pleasant Bayou No. 2 well; Pleasant Bayou hybrid power system; Environmental monitoring at Pleasant Bayou; and Plug abandonment and well site restoration of three geopressured-geothermal test sites. 197 figs., 64 tabs.

  8. 76 FR 41755 - Eastern Arizona Counties Resource Advisory; Meeting

    Science.gov (United States)

    2011-07-15

    ... DEPARTMENT OF AGRICULTURE Forest Service Eastern Arizona Counties Resource Advisory; Meeting AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Eastern Arizona Counties Resource... FURTHER INFORMATION CONTACT: Julia Faith Rivera, RAC Program Manager, Eastern Arizona Counties Resource...

  9. A linear bi-level multi-objective program for optimal allocation of water resources.

    Directory of Open Access Journals (Sweden)

    Ijaz Ahmad

    Full Text Available This paper presents a simple bi-level multi-objective linear program (BLMOLP with a hierarchical structure consisting of reservoir managers and several water use sectors under a multi-objective framework for the optimal allocation of limited water resources. Being the upper level decision makers (i.e., leader in the hierarchy, the reservoir managers control the water allocation system and tend to create a balance among the competing water users thereby maximizing the total benefits to the society. On the other hand, the competing water use sectors, being the lower level decision makers (i.e., followers in the hierarchy, aim only to maximize individual sectoral benefits. This multi-objective bi-level optimization problem can be solved using the simultaneous compromise constraint (SICCON technique which creates a compromise between upper and lower level decision makers (DMs, and transforms the multi-objective function into a single decision-making problem. The bi-level model developed in this study has been applied to the Swat River basin in Pakistan for the optimal allocation of water resources among competing water demand sectors and different scenarios have been developed. The application of the model in this study shows that the SICCON is a simple, applicable and feasible approach to solve the BLMOLP problem. Finally, the comparisons of the model results show that the optimization model is practical and efficient when it is applied to different conditions with priorities assigned to various water users.

  10. Diabetes HealthSense: Resources for Living Well

    Medline Plus

    Full Text Available ... 65+) Type of Resource Select one: Printable documents Online programs In-person programs Videos and podcasts Presentations Mobile Application Website Webinar Language Select one: English Spanish Vietnamese Privacy Policy | Freedom ...

  11. Diabetes HealthSense: Resources for Living Well

    Medline Plus

    Full Text Available ... a program to prevent or delay the onset of the disease. MOVE! This national weight management program is designed to help veterans lose weight, ... professional K-8th grade Community health worker Community organization Age ... (65+) Type of Resource Select one: Printable documents Online programs In- ...

  12. Space Science Education Resource Directory

    Science.gov (United States)

    Christian, C. A.; Scollick, K.

    The Office of Space Science (OSS) of NASA supports educational programs as a by-product of the research it funds through missions and investigative programs. A rich suite of resources for public use is available including multimedia materials, online resources, hardcopies and other items. The OSS supported creation of a resource catalog through a group lead by individuals at STScI that ultimately will provide an easy-to-use and user-friendly search capability to access products. This paper describes the underlying architecture of that catalog, including the challenge to develop a system for characterizing education products through appropriate metadata. The system must also be meaningful to a large clientele including educators, scientists, students, and informal science educators. An additional goal was to seamlessly exchange data with existing federally supported educational systems as well as local systems. The goals, requirements, and standards for the catalog will be presented to illuminate the rationale for the implementation ultimately adopted.

  13. 30 CFR 401.12 - Program management.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Program management. 401.12 Section 401.12 Mineral Resources GEOLOGICAL SURVEY, DEPARTMENT OF THE INTERIOR STATE WATER RESEARCH INSTITUTE PROGRAM Application and Management Procedures § 401.12 Program management. (a) Upon approval of each fiscal year's...

  14. 30 CFR 402.13 - Program management.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Program management. 402.13 Section 402.13... WATER-RESOURCES TECHNOLOGY DEVELOPMENT PROGRAM Application, Evaluation, and Management Procedures § 402.13 Program management. (a) After the conclusion of negotiations, the USGS will transmit a grant or...

  15. Resources for GCSE.

    Science.gov (United States)

    Anderton, Alain

    1987-01-01

    Argues that new resources are needed to help teachers prepare students for the new General Certificate in Secondary Education (GCSE) examination. Compares previous examinations with new examinations to illustrate the problem. Presents textbooks, workbooks, computer programs, and other curriculum materials to demonstrate the gap between resources…

  16. 30 CFR 402.6 - Water-Resources Research Program.

    Science.gov (United States)

    2010-07-01

    ... productivity of water when used for agricultural, municipal, and commercial purposes; and (8) The economic, legal, engineering, social, recreational, biological, geographic, ecological, and other aspects of water... interpreting the results of scientific and engineering research on water-resources problems. (10) Providing...

  17. Cloud resource orchestration programming : Overview, issues and directions

    NARCIS (Netherlands)

    Ranjan, Rajiv; Benatallah, Boualem; Dustdar, Schahram; Papazoglou, M.

    Cloud computing provides on-demand access to affordable hardware (e.g., multi-core CPUs, GPUs, disks, and networking equipment) and software (e.g., databases, application servers, load-balancers, data processing frameworks, etc.) resources. The pervasiveness and power of cloud computing alleviates

  18. An object-oriented programming system for the integration of internet-based bioinformatics resources.

    Science.gov (United States)

    Beveridge, Allan

    2006-01-01

    The Internet consists of a vast inhomogeneous reservoir of data. Developing software that can integrate a wide variety of different data sources is a major challenge that must be addressed for the realisation of the full potential of the Internet as a scientific research tool. This article presents a semi-automated object-oriented programming system for integrating web-based resources. We demonstrate that the current Internet standards (HTML, CGI [common gateway interface], Java, etc.) can be exploited to develop a data retrieval system that scans existing web interfaces and then uses a set of rules to generate new Java code that can automatically retrieve data from the Web. The validity of the software has been demonstrated by testing it on several biological databases. We also examine the current limitations of the Internet and discuss the need for the development of universal standards for web-based data.

  19. NATURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

    Energy Technology Data Exchange (ETDEWEB)

    GREEN,T.ET AL.

    2003-12-31

    Brookhaven National Laboratory (BNL) is located near the geographic center of Long Island, New York. The Laboratory is situated on 5,265 acres of land composed of Pine Barrens habitat with a central area developed for Laboratory work. In the mid-1990s BNL began developing a wildlife management program. This program was guided by the Wildlife Management Plan (WMP), which was reviewed and approved by various state and federal agencies in September 1999. The WMP primarily addressed concerns with the protection of New York State threatened, endangered, or species of concern, as well as deer populations, invasive species management, and the revegetation of the area surrounding the Relativistic Heavy Ion Collider (RHIC). The WMP provided a strong and sound basis for wildlife management and established a basis for forward motion and the development of this document, the Natural Resource Management Plan (NRMP), which will guide the natural resource management program for BNL. The body of this plan establishes the management goals and actions necessary for managing the natural resources at BNL. The appendices provide specific management requirements for threatened and endangered amphibians and fish (Appendices A and B respectively), lists of actions in tabular format (Appendix C), and regulatory drivers for the Natural Resource Program (Appendix D). The purpose of the Natural Resource Management Plan is to provide management guidance, promote stewardship of the natural resources found at BNL, and to integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, adaptive ecosystem management, compliance, integration with other plans and requirements, and incorporation of community involvement, where applicable.

  20. Inclusion of Students with Special Education Needs in French as a Second Language Programs: A Review of Canadian Policy and Resource Documents

    Science.gov (United States)

    Muhling, Stefanie; Mady, Callie

    2017-01-01

    This article describes a document analysis of policy and resource documents pertaining to inclusion of students with special education needs (SSEN) in Canadian French as a Second Language (FSL) programs. By recognizing gaps and acknowledging advancements, we aim to inform current implementation and future development of inclusive policy. Document…

  1. NURE aerial gamma-ray and magnetic-reconnaissance survey portions of New Mexico, Arizona, and Texas. Volume I. Instrumentation and data reduction. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1981-09-01

    As part of the Department of Energy (DOE) National Uranium Resource Evaluation Program, a rotary-wing high sensitivity radiometric and magnetic survey was flown covering portions of the State of New Mexico, Arizona and Texas. The survey encompassed six 1:250,000 scale quadrangles, Holbrook, El Paso, Las Cruces, Carlsbad, Fort Sumner and Roswell. The survey was flown with a Sikorsky S58T helicopter equipped with a high sensitivity gamma ray spectrometer which was calibrated at the DOE calibration facilities at Walker Field in Grand Junction, Colorado, and the Dynamic Test Range at Lake Mead, Arizona. The radiometric data were processed to compensate for Compton scattering effects and altitude variations. The data were normalized to 400 feet terrain clearance. The reduced data is presented in the form of stacked profiles, standard deviation anomaly plots, histogram plots and microfiche listings. The results of the geologic interpretation of the radiometric data together with the profiles, anomaly maps and histograms are presented in the individual quadrangle reports. The survey was awarded to LKB Resources, Inc. which completed the data acquisition. In April, 1980 Carson Helicopters, Inc. and Carson Geoscience Company agreed to manage the project and complete delivery of this final report.

  2. NURE aerial gamma-ray and magnetic-reconnaissance survey portions of New Mexico, Arizona, and Texas. Volume I. Instrumentation and data reduction. Final report

    International Nuclear Information System (INIS)

    1981-09-01

    As part of the Department of Energy (DOE) National Uranium Resource Evaluation Program, a rotary-wing high sensitivity radiometric and magnetic survey was flown covering portions of the State of New Mexico, Arizona and Texas. The survey encompassed six 1:250,000 scale quadrangles, Holbrook, El Paso, Las Cruces, Carlsbad, Fort Sumner and Roswell. The survey was flown with a Sikorsky S58T helicopter equipped with a high sensitivity gamma ray spectrometer which was calibrated at the DOE calibration facilities at Walker Field in Grand Junction, Colorado, and the Dynamic Test Range at Lake Mead, Arizona. The radiometric data were processed to compensate for Compton scattering effects and altitude variations. The data were normalized to 400 feet terrain clearance. The reduced data is presented in the form of stacked profiles, standard deviation anomaly plots, histogram plots and microfiche listings. The results of the geologic interpretation of the radiometric data together with the profiles, anomaly maps and histograms are presented in the individual quadrangle reports. The survey was awarded to LKB Resources, Inc. which completed the data acquisition. In April, 1980 Carson Helicopters, Inc. and Carson Geoscience Company agreed to manage the project and complete delivery of this final report

  3. A Policy study on cooperation for the development of underground resources in North Korea

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Jung Nam [Korea Energy Economics Institute, Euiwang (Korea)

    1999-03-01

    For the smooth promotion of joint development program of underground resources in North Korea, it requires a domestic legal authority applicable when a private company begins the development program of underground resources in North Korea. It is recommended that the supply of initial fund of resources development program in North Korea will utilize the supply method of existing resources development subsidizing fund instead of establishing new fund. In the case of enlarging its program by minerals, it is desirable to support it by creating the South-North resources development cooperation fund for a certain period to attract voluntary participation of the private sector. In this study, minerals able to develop among natural minerals in North Korea were classified and presented by grouping according to the higher order. Also, a plan for institutionalizing this was sought by connecting a development program by types of minerals for the smooth operation of South-North resources development cooperation program. Considering types of minerals, area, and the size and cost of development, it should be operated step by step, but for programs realizable at once, it should be started in its early stage. It is recommended to review a step by step plan for mineral resources development in North Korea continuously in connection with other economic cooperation sector such as the manufacturing industry. (author). 30 refs., 40 tabs.

  4. 77 FR 59197 - Epilepsy Program

    Science.gov (United States)

    2012-09-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Epilepsy... Program Expansion Supplement Award to the Epilepsy Foundation of America. SUMMARY: The Health Resources... Child Health Bureau's Epilepsy Program to the Epilepsy Foundation of America (U23MC19824) to support...

  5. Approximate Dynamic Programming for Military Resource Allocation

    Science.gov (United States)

    2014-12-26

    To my wife and children ; Mom, Poppa, and Grammy. v Acknowledgements I would like to express my sincere appreciation to my research advisor Dr. Darryl...the first stage and using weapons in the second stage. Because the second stage uti - lizes a single resource class, the optimality of the MMR...generates two children , so the size of the next generation remains constant. Based on the recommendations of Chu and Beasley [27], these operators

  6. Acknowledging Spanish and English resources during mathematical reasoning

    Science.gov (United States)

    LópezLeiva, Carlos A.; Torres, Zayoni; Khisty, Lena L.

    2013-12-01

    As English-only efforts continue in the US schooling system, dual-language programs have served as attempts to preserve students' home language. An after-school, dual-language, Spanish-English, mathematics program, Los Rayos was developed in a predominantly Mexican/Mexican-American neighborhood in Chicago. As participant observers with a sociocultural perspective, we explored the linguistic and personal resources used by participating 4th grade bilingual Latina/o students. We found that students used imaginative, playful, and hybrid linguistic resources to make sense of and solve probability tasks when engaged within a zone of mathematical practice. Results challenge narrow perspectives on bilingual students' linguistic resources. Language implications are discussed.

  7. Diabetes HealthSense: Resources for Living Well

    Medline Plus

    Full Text Available ... Manage Your Weight Small Steps. Big Rewards. Your GAME PLAN to Prevent Type 2 Diabetes: Information for ... 65+) Type of Resource Select one: Printable documents Online programs In-person programs Videos and podcasts Presentations ...

  8. 45 CFR 1304.52 - Human resources management.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Human resources management. 1304.52 Section 1304.52 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT... DELEGATE AGENCIES Program Design and Management § 1304.52 Human resources management. (a) Organizational...

  9. Introduction to a Special Issue of the Journal of Immunological Methods: Building global resource programs to support HIV/AIDS clinical trial studies.

    Science.gov (United States)

    Sanchez, Ana M; Denny, Thomas N; O'Gorman, Maurice

    2014-07-01

    This Special Issue of the Journal of Immunological Methods includes 16 manuscripts describing quality assurance activities related to virologic and immunologic monitoring of six global laboratory resource programs that support international HIV/AIDS clinical trial studies: Collaboration for AIDS Vaccine Discovery (CAVD); Center for HIV/AIDS Vaccine Immunology (CHAVI); External Quality Assurance Program Oversight Laboratory (EQAPOL); HIV Vaccine Trial Network (HVTN); International AIDS Vaccine Initiative (IAVI); and Immunology Quality Assessment (IQA). The reports from these programs address the many components required to develop comprehensive quality control activities and subsequent quality assurance programs for immune monitoring in global clinical trials including: all aspects of processing, storing, and quality assessment of PBMC preparations used ubiquitously in HIV clinical trials, the development and optimization of assays for CD8 HIV responses and HIV neutralization, a comprehensive global HIV virus repository, and reports on the development and execution of novel external proficiency testing programs for immunophenotyping, intracellular cytokine staining, ELISPOT and luminex based cytokine measurements. In addition, there are articles describing the implementation of Good Clinical Laboratory Practices (GCLP) in a large quality assurance laboratory, the development of statistical methods specific for external proficiency testing assessment, a discussion on the ability to set objective thresholds for measuring rare events by flow cytometry, and finally, a manuscript which addresses a framework for the structured reporting of T cell immune function based assays. It is anticipated that this series of manuscripts covering a wide range of quality assurance activities associated with the conduct of global clinical trials will provide a resource for individuals and programs involved in improving the harmonization, standardization, accuracy, and sensitivity of

  10. Distributed energy resources management using plug-in hybrid electric vehicles as a fuel-shifting demand response resource

    DEFF Research Database (Denmark)

    Morais, Hugo; Sousa, Tiago; Soares, J.

    2015-01-01

    In the smart grids context, distributed energy resources management plays an important role in the power systems' operation. Battery electric vehicles and plug-in hybrid electric vehicles should be important resources in the future distribution networks operation. Therefore, it is important...... to develop adequate methodologies to schedule the electric vehicles' charge and discharge processes, avoiding network congestions and providing ancillary services.This paper proposes the participation of plug-in hybrid electric vehicles in fuel shifting demand response programs. Two services are proposed......, namely the fuel shifting and the fuel discharging. The fuel shifting program consists in replacing the electric energy by fossil fuels in plug-in hybrid electric vehicles daily trips, and the fuel discharge program consists in use of their internal combustion engine to generate electricity injecting...

  11. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Continuous Certification Requirements SSR Login MIPS Resources and Education Quality and Safety Conference Trauma Trauma Programs Trauma Programs About Trauma Programs Violence Prevention BleedingControl.org Trauma Quality Programs National Trauma ...

  12. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Program About ACS NSQIP Join ACS NSQIP Now Collaboratives Hospital Compare Quality and Safety Conference Participant Use ... Asked Questions Resources Educational Resources Educational Resources E-Learning Entering Resident Readiness Assessment Evidence-Based Decisions in ...

  13. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Resources Educational Resources E-Learning Entering Resident Readiness Assessment Evidence-Based Decisions in Surgery Medical Student Resources ... checklist Evaluation (Complete the Ostomy Patient Survey . We need your opinion!) Program outcomes The ACS Ostomy Home ...

  14. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Congress Educational Program Events and Special Activities Resources Housing and Travel Exhibitors Media Information Clinical Congress 2017 ... Requirements Application Instructions Activities of the Academy Application Cycle and Deadlines Frequently Asked Questions Resources Educational Resources ...

  15. Bataan Coastal Resource Management Programs: Environmental, Socio-Economic, and Implementation Issues from Stakeholders’ Views

    Directory of Open Access Journals (Sweden)

    Alvin B. Cervania

    2018-02-01

    Full Text Available A study on the status of Bataan’s coastal zones, and the issues on the province’s coastal resource management (CRM programs under an integrated framework was commissioned by the Department of Science and Technology-Region III in the Philippines. Twenty-eight representative coastal villages and 11 water testing sites served as study areas. The research participants totalled to 1,300. Focused group discussions, survey and interviews, laboratory testing, documentary analysis, and literature review were used in the data gathering. It was concluded that the province’s coastal zones are in a disturbed state, which has negative implications to its already subsistent coastal population and important coastal economic activities. The province’s CRM projects have been arbitrary and intermittent. There are too few conservation initiatives due to scarcity of baseline data necessary for more methodical CRM programs. There is poor grassroots level involvement in CRM decision-making processes as well which clearly defeats the essence of integrated coastal management. A coordinated effort to strengthen stakeholder participation in critical CRM stages, and to conduct more comprehensive profilings and assessments of the province’s coastal environment involving the government, academics, and scientists are recommended to substantiate stakeholder involvement and increase the quality of data for CRM projects.

  16. Evaluation of 4 weeks' neonatal antiretroviral prophylaxis as a component of a prevention of mother-to-child transmission program in a resource-rich setting.

    LENUS (Irish Health Repository)

    Ferguson, Wendy

    2011-05-01

    In resource-rich settings, universal adoption of a 4- rather than 6-week neonatal antiretroviral (ARV) prophylaxis regimen could reduce toxicity and results in cost savings, provided prevention of mother-to-child transmission program effectiveness is not compromised.

  17. GEO/SQL in water resource manegement

    Directory of Open Access Journals (Sweden)

    Andrej Vidmar

    1992-12-01

    Full Text Available The development of water resource management concepts shouis the problem of collecting, combining, and using alphanumerical and graphical spatial data. The solution of this problem lies in the use of geographic information systems - GIS. This paper describes the usefulness of GIS programming tool Geo/SQL in water resources management.

  18. Information Technology Resources Assessment

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    The Information Technology Resources Assessment (ITRA) is being published as a companion document to the Department of Energy (DOE) FY 1994--FY 1998 Information Resources Management Long-Range Plan. This document represents a collaborative effort between the Office of Information Resources Management and the Office of Energy Research that was undertaken to achieve, in part, the Technology Strategic Objective of IRM Vision 21. An integral part of this objective, technology forecasting provides an understanding of the information technology horizon and presents a perspective and focus on technologies of particular interest to DOE program activities. Specifically, this document provides site planners with an overview of the status and use of new information technology for their planning consideration.

  19. Genomic Resources for Cancer Epidemiology

    Science.gov (United States)

    This page provides links to research resources, complied by the Epidemiology and Genomics Research Program, that may be of interest to genetic epidemiologists conducting cancer research, but is not exhaustive.

  20. Project ECHO: A Telementoring Program for Cervical Cancer Prevention and Treatment in Low-Resource Settings

    Directory of Open Access Journals (Sweden)

    Melissa S. Lopez

    2017-10-01

    Full Text Available Cervical cancer incidence and mortality rates are significantly higher in low- and middle-income countries compared with the United States and other developed countries. This disparity is caused by decreased access to screening, often coupled with low numbers of trained providers offering cancer prevention and treatment services. However, similar disparities are also found in underserved areas of the United States, such as the Texas-Mexico border, where cervical cancer mortality rates are 30% higher than in the rest of Texas. To address these issues, we have adopted the Project ECHO (Extension for Community Healthcare Outcomes program, a low-cost telementoring model previously proven to be successful in increasing local capacity, improving patient management skills, and ultimately improving patient outcomes in rural and underserved areas. We use the Project ECHO model to educate local providers in the management of cervical dysplasia in a low-resource region of Texas and have adapted it to inform strategies for the management of advanced cervical and breast cancer in Latin America and sub-Saharan Africa. This innovative approach, using ECHO, is part of a larger strategy to enhance clinical skills and develop collaborative projects between academic centers and partners in low-resource regions.

  1. Natural-resource management in Bangladesh

    International Nuclear Information System (INIS)

    Hasan, S.; Mulamoottil, G.

    1994-01-01

    The paper discusses the major natural resource management issues in relation to land, forests, and water in Bangladesh. It shows how government policies and programs in one sector may affect other sectors. A lack of land use, and forest policies can be responsible for degradation of agricultural land and deforestation. The paper argues that better management of the natural resources can only be achieved by an integrated approach covering all the sectors of development. In Bangladesh, with a freely elected government in power, there is a unique opportunity to formulate an integrated natural resource management strategy. 44 refs, 2 figs, 1 tab

  2. Human Resource Managements as a part of the Human Factors Management Program(HFMP) for Nuclear Power Plants

    International Nuclear Information System (INIS)

    Kim, DaeHo; Lee, YongHee; Lee, JungWoon; Kim, Younggab

    2007-01-01

    Programs for the effective implementation and management of human factor issues in nuclear power plants (NPPs) should contain technical criteria, an establishment of a job process, and activities for job improvements and be a system through which human factors can be managed in an integrated way. Human factors to be managed should include those related to an operation of plants as well as those related to a plant design as mentioned in NUREG-0800(2004), NUREG- 0711(2004), and NUREG-0700(2002). Human factor items to be managed for an operation of plants are listed in the PSR (Periodic Safety Review) items defined in the Enforcement of Regulation of the Atomic Energy Act. They are procedures, a work management system including a shift work management, a qualification management of plant personnel, training, a work amount assessment, a MMI (Man Machine Interface), and the use of experience. Among these factors, factors related to a human resource management include work management systems and the status of a work management including shift work, a qualification management ensuring qualified workers on duty at all times, and the systems for and the status of training and education. This paper addresses the scope of a human resource management, guidelines and procedures to be developed for a human resource management, and considerations critical in the development of guidelines and procedures

  3. Communication, Scheduling, and Resource Management in SINA

    NARCIS (Netherlands)

    Tripathi, A.; Aksit, Mehmet

    1988-01-01

    In this article we present the object-oriented constructs for communication and concurrent programming in the SINA programming language. The object encapsulation mechanism of SINA allows implementations of hierarchically structured resource management systems and alleviates some of the problems that

  4. Diabetes HealthSense: Resources for Living Well

    Medline Plus

    Full Text Available ... Community health worker Community organization Age Select one: Child Teen and young adult Adult Older adult (65+) Type of Resource Select one: Printable documents Online programs In-person programs Videos and podcasts Presentations Mobile Application Website Webinar Language ...

  5. Role of SIRT6 in Metabolic Reprogramming During Colorectal Carcinoma

    Science.gov (United States)

    2015-09-01

    One of the main targets for LKB1 is AMP - activated protein kinase (AMPK), a key enzyme that regulates cellular energy homeostasis [128]. LKB1...EC. Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 2010;49:304–11. [55] Rahman M, Nirala NK, Singh A...Juhnn YS. Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via

  6. National Center for Mathematics and Science - teacher resources

    Science.gov (United States)

    Mathematics and Science (NCISLA) HOME | PROGRAM OVERVIEW | RESEARCH AND PROFESSIONAL DEVELOPMENT support and improve student understanding of mathematics and science. The instructional resources listed Resources (CD)Powerful Practices in Mathematics and Science A multimedia product for educators, professional

  7. Analytical methods manual for the Mineral Resource Surveys Program, U.S. Geological Survey

    Science.gov (United States)

    Arbogast, Belinda F.

    1996-01-01

    The analytical methods validated by the Mineral Resource Surveys Program, Geologic Division, is the subject of this manual. This edition replaces the methods portion of Open-File Report 90-668 published in 1990. Newer methods may be used which have been approved by the quality assurance (QA) project and are on file with the QA coordinator.This manual is intended primarily for use by laboratory scientists; this manual can also assist laboratory users to evaluate the data they receive. The analytical methods are written in a step by step approach so that they may be used as a training tool and provide detailed documentation of the procedures for quality assurance. A "Catalog of Services" is available for customer (submitter) use with brief listings of:the element(s)/species determined,method of determination,reference to cite,contact person,summary of the technique,and analyte concentration range.For a copy please contact the Branch office at (303) 236-1800 or fax (303) 236-3200.

  8. The Estonian national program for sustainable resource development and its connection with teaching about fossil fuels in chemistry courses

    International Nuclear Information System (INIS)

    Karik, H.

    1996-01-01

    The conception of sustainable resource development worked out under the initiative of the United Nations (UN) actualizes ideas for improving the health of people and the environment. The needs of people are to he addressed and, simultaneously, natural resources preserved. That is ,why ecological and economic expenses are to he integrated and flow sheets of industrial plants are to be reorganized in order to utilize natural resources in a rational way. The association of Estonia with the resolution of the UN Conference on Environmental Development held in Rio de Janeiro and the resolution of the Estonian Parliament concerning The National Program of Sustainable Development require changes in our lifestyle. Chemical education in schools has to support a change in the way of thinking and many concrete subjects can be connected with the problems of sustainable development. Metallic elements get into the environment mostly with fuel combustion ashes. According to various prognoses, fossil fuel resources will last for a thousand years. This means that more and more metallic compounds are thrown into the environment. Dispersion of metals in the air, water bodies and soil is continuously increasing. Finally, they reach the food chain and to the human body. As a result, toxicosis, illnesses, and inadvisable dislocations in organic life may occur. The trend to use ash as a raw material for metal production is considered to have some prospective economically attractive application. This would be one possible way of sustainable resource development to avoid the increase of environmental pollution and increase production of the corresponding metals

  9. Mexico's "Telesecundaria" Program and Equitable Access to Resources

    Science.gov (United States)

    Craig, Dana; Etcheverry, Jose; Ferris, Stefan

    2016-01-01

    This Note provides an analysis of Mexico's "Telesecundaria" program within the context of Mexico's new education reform framework offering a succinct background of the project, as well as key policy lessons that can be useful for other jurisdictions interested in the development of distance education programs. This Note uses a literature…

  10. Ostomy Home Skills Program

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    Full Text Available ... Trauma Trauma Programs Trauma Programs About Trauma Programs Violence Prevention BleedingControl.org Trauma Quality Programs National Trauma ... Benefits Current Openings Newsroom Newsroom Newsroom Press Releases Media Resources The FIRST Trial ACS Publications ACS in ...

  11. Paediatric cardiology programs in countries with limited resources: how to bridge the gap.

    Science.gov (United States)

    Sulafa, K M Ali

    2010-07-01

    Establishing paediatric cardiology service in a country with limited resources like Sudan is a challenging task. A paediatric cardiac team was formed then the services in different disciplines were gradually established. Echocardiography (echo) clinics were founded in tertiary and peripheral hospitals. Cardiac catheterization (cath) was established at the Sudan Heart Centre (SHC) in 2004 and over 400 procedures had been performed including interventional catheterization like pulmonary valve dilatation, patent ductus arteriosus and atrial septal defect device closure. Congenital heart surgery started in 2001, currently 200 cases are done each year including closed procedures as well as open heart procedures for patients weighing more than 8 kg. Cardiology-cardiac surgery as well as adult congenital heart disease meetings were held and contributed positively to the services. The cardiology-cardiac surgery scientific club meeting was founded as a forum for academic discussions. A fellowship program was established in 2004 and included seven candidates trained in paediatric cardiology and intensive care. Two training courses had been established: congenital heart disease echo and paediatric electrocardiogram interpretation. Links with regional and international cardiac centres had important roles in consolidating our program. Significant obstacles face our service due to the small number of trained personnel, high cost of procedures, the lack of regular supplies and lack of cardiac intensive care facilities for young infants. Bridging the huge gap needs extensive official as well as non-governmental efforts, training more staff, supporting families and collaboration with regional and international centres.

  12. Programming Models in HPC

    Energy Technology Data Exchange (ETDEWEB)

    Shipman, Galen M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-13

    These are the slides for a presentation on programming models in HPC, at the Los Alamos National Laboratory's Parallel Computing Summer School. The following topics are covered: Flynn's Taxonomy of computer architectures; single instruction single data; single instruction multiple data; multiple instruction multiple data; address space organization; definition of Trinity (Intel Xeon-Phi is a MIMD architecture); single program multiple data; multiple program multiple data; ExMatEx workflow overview; definition of a programming model, programming languages, runtime systems; programming model and environments; MPI (Message Passing Interface); OpenMP; Kokkos (Performance Portable Thread-Parallel Programming Model); Kokkos abstractions, patterns, policies, and spaces; RAJA, a systematic approach to node-level portability and tuning; overview of the Legion Programming Model; mapping tasks and data to hardware resources; interoperability: supporting task-level models; Legion S3D execution and performance details; workflow, integration of external resources into the programming model.

  13. Diabetes HealthSense: Resources for Living Well

    Medline Plus

    Full Text Available ... Take my medicine I Am A Select one: Person with diabetes Person with prediabetes Person at risk for diabetes Family member, friend, or ... Resource Select one: Printable documents Online programs In-person programs Videos and podcasts Presentations Mobile Application Website ...

  14. A Running Start: Resource Guide for Youth Running Programs

    Science.gov (United States)

    Jenny, Seth; Becker, Andrew; Armstrong, Tess

    2016-01-01

    The lack of physical activity is an epidemic problem among American youth today. In order to combat this, many schools are incorporating youth running programs as a part of their comprehensive school physical activity programs. These youth running programs are being implemented before or after school, at school during recess at the elementary…

  15. Application of dynamic programming for the analysis of complex water resources systems : a case study on the Mahaweli River basin development in Sri Lanka

    NARCIS (Netherlands)

    Kularathna, M.D.U.P.

    1992-01-01

    The technique of Stochastic Dynamic Programming (SDP) is ideally suited for operation policy analyses of water resources systems. However SDP has a major drawback which is appropriately termed as its "curse of dimensionality".

    Aggregation/Disaggregation techniques based on SDP and

  16. 20 CFR 628.215 - State Human Resource Investment Council.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false State Human Resource Investment Council. 628... PROGRAMS UNDER TITLE II OF THE JOB TRAINING PARTNERSHIP ACT State Planning § 628.215 State Human Resource..., 702, and 703 of the Act, establish a State Human Resource Investment Council (HRIC). The HRIC's...

  17. 75 FR 2549 - Health Center Program

    Science.gov (United States)

    2010-01-15

    ... Program AGENCY: Health Resources and Services Administration, HHS ACTION: Notice of Noncompetitive Replacement Award to Regional Health Care Affiliates. SUMMARY: The Health Resources and Services Administration (HRSA) will be transferring Health Center Program (section 330 of the Public Health Service Act...

  18. Ohio Career Resource.

    Science.gov (United States)

    Ohio State Dept. of Education, Columbus. Div. of Career-Technical and Adult Education.

    This resource is designed to provide Ohio labor market information for use with advisory committees to stimulate and inform dialogue about the current evaluation and future planning of programs. It provides reports for 23 career fields in 6 career clusters. Each report highlights careers and occupations in the field and answers these questions:…

  19. An approximate dynamic programming approach to resource management in multi-cloud scenarios

    Science.gov (United States)

    Pietrabissa, Antonio; Priscoli, Francesco Delli; Di Giorgio, Alessandro; Giuseppi, Alessandro; Panfili, Martina; Suraci, Vincenzo

    2017-03-01

    The programmability and the virtualisation of network resources are crucial to deploy scalable Information and Communications Technology (ICT) services. The increasing demand of cloud services, mainly devoted to the storage and computing, requires a new functional element, the Cloud Management Broker (CMB), aimed at managing multiple cloud resources to meet the customers' requirements and, simultaneously, to optimise their usage. This paper proposes a multi-cloud resource allocation algorithm that manages the resource requests with the aim of maximising the CMB revenue over time. The algorithm is based on Markov decision process modelling and relies on reinforcement learning techniques to find online an approximate solution.

  20. 30 CFR 906.16 - Required program amendments.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Required program amendments. 906.16 Section 906.16 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE COLORADO § 906.16 Required program...

  1. Laboratory and field studies related to the Hydrologic Resources Management Program. Progress report, October 1, 1993--September 30, 1994

    International Nuclear Information System (INIS)

    Thompson, J.L.

    1995-03-01

    This report describes the work done at Los Alamos in FY 1994 for the Hydrologic Resources Management Program, a multi-organization project funded by the US Department of Energy/Nevada Operations Office. The authors participated in cooperative collaborations with University of California (UC), Berkeley, the Yucca Mountain Project, the Underground Test Area Operable Unit, and other participating organizations within the Hydrologic Resources Management Program (HRMP). They provided operational support to the Nevada Test Site (NTS) organizations by testing a water-evaporation system, championing the use of high-sensitivity logging equipment during drillbacks, and participating in the planning and execution of drilling operations at two nuclear test sites. Los Alamos personnel cooperated in preparing a proposal to drill beside and under a nuclear test located in unsaturated media. The authors gave assistance in laboratory work related to colloid migration and actinide sorption. In conjunction with personnel from the Lawrence Livermore Laboratory, they collected water samples from 10 wells at the NTS that are known to contain radionuclides. Their analyses of these samples suggest that radionuclides may not be moving away from cavity zones at appreciable rates. Recent field sampling shows clearly the need to purge wells of materials introduced during drilling and illustrates the inconsistency between water samples taken by bailing and those taken by pumping. 36 refs

  2. Impact of an Educational Program to Reduce Healthcare Resources in Community-Acquired Pneumonia: The EDUCAP Randomized Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Jordi Adamuz

    Full Text Available Additional healthcare visits and rehospitalizations after discharge are frequent among patients with community-acquired pneumonia (CAP and have a major impact on healthcare costs. We aimed to determine whether the implementation of an individualized educational program for hospitalized patients with CAP would decrease subsequent healthcare visits and readmissions within 30 days of hospital discharge.A multicenter, randomized trial was conducted from January 1, 2011 to October 31, 2014 at three hospitals in Spain. We randomly allocated immunocompetent adults patients hospitalized for CAP to receive either an individualized educational program or conventional information before discharge. The educational program included recommendations regarding fluid intake, adherence to drug therapy and preventive vaccines, knowledge and management of the disease, progressive adaptive physical activity, and counseling for alcohol and smoking cessation. The primary trial endpoint was a composite of the frequency of additional healthcare visits and rehospitalizations within 30 days of hospital discharge. Intention-to-treat analysis was performed.We assigned 102 patients to receive the individualized educational program and 105 to receive conventional information. The frequency of the composite primary end point was 23.5% following the individualized program and 42.9% following the conventional information (difference, -19.4%; 95% confidence interval, -6.5% to -31.2%; P = 0.003.The implementation of an individualized educational program for hospitalized patients with CAP was effective in reducing subsequent healthcare visits and rehospitalizations within 30 days of discharge. Such a strategy may help optimize available healthcare resources and identify post-acute care needs in patients with CAP.Controlled-Trials.com ISRCTN39531840.

  3. Normal Tissue Complication Probability Estimation by the Lyman-Kutcher-Burman Method Does Not Accurately Predict Spinal Cord Tolerance to Stereotactic Radiosurgery

    International Nuclear Information System (INIS)

    Daly, Megan E.; Luxton, Gary; Choi, Clara Y.H.; Gibbs, Iris C.; Chang, Steven D.; Adler, John R.; Soltys, Scott G.

    2012-01-01

    Purpose: To determine whether normal tissue complication probability (NTCP) analyses of the human spinal cord by use of the Lyman-Kutcher-Burman (LKB) model, supplemented by linear–quadratic modeling to account for the effect of fractionation, predict the risk of myelopathy from stereotactic radiosurgery (SRS). Methods and Materials: From November 2001 to July 2008, 24 spinal hemangioblastomas in 17 patients were treated with SRS. Of the tumors, 17 received 1 fraction with a median dose of 20 Gy (range, 18–30 Gy) and 7 received 20 to 25 Gy in 2 or 3 sessions, with cord maximum doses of 22.7 Gy (range, 17.8–30.9 Gy) and 22.0 Gy (range, 20.2–26.6 Gy), respectively. By use of conventional values for α/β, volume parameter n, 50% complication probability dose TD 50 , and inverse slope parameter m, a computationally simplified implementation of the LKB model was used to calculate the biologically equivalent uniform dose and NTCP for each treatment. Exploratory calculations were performed with alternate values of α/β and n. Results: In this study 1 case (4%) of myelopathy occurred. The LKB model using radiobiological parameters from Emami and the logistic model with parameters from Schultheiss overestimated complication rates, predicting 13 complications (54%) and 18 complications (75%), respectively. An increase in the volume parameter (n), to assume greater parallel organization, improved the predictive value of the models. Maximum-likelihood LKB fitting of α/β and n yielded better predictions (0.7 complications), with n = 0.023 and α/β = 17.8 Gy. Conclusions: The spinal cord tolerance to the dosimetry of SRS is higher than predicted by the LKB model using any set of accepted parameters. Only a high α/β value in the LKB model and only a large volume effect in the logistic model with Schultheiss data could explain the low number of complications observed. This finding emphasizes that radiobiological models traditionally used to estimate spinal cord NTCP

  4. The SCEC/UseIT Intern Program: Creating Open-Source Visualization Software Using Diverse Resources

    Science.gov (United States)

    Francoeur, H.; Callaghan, S.; Perry, S.; Jordan, T.

    2004-12-01

    The Southern California Earthquake Center undergraduate IT intern program (SCEC UseIT) conducts IT research to benefit collaborative earth science research. Through this program, interns have developed real-time, interactive, 3D visualization software using open-source tools. Dubbed LA3D, a distribution of this software is now in use by the seismic community. LA3D enables the user to interactively view Southern California datasets and models of importance to earthquake scientists, such as faults, earthquakes, fault blocks, digital elevation models, and seismic hazard maps. LA3D is now being extended to support visualizations anywhere on the planet. The new software, called SCEC-VIDEO (Virtual Interactive Display of Earth Objects), makes use of a modular, plugin-based software architecture which supports easy development and integration of new data sets. Currently SCEC-VIDEO is in beta testing, with a full open-source release slated for the future. Both LA3D and SCEC-VIDEO were developed using a wide variety of software technologies. These, which included relational databases, web services, software management technologies, and 3-D graphics in Java, were necessary to integrate the heterogeneous array of data sources which comprise our software. Currently the interns are working to integrate new technologies and larger data sets to increase software functionality and value. In addition, both LA3D and SCEC-VIDEO allow the user to script and create movies. Thus program interns with computer science backgrounds have been writing software while interns with other interests, such as cinema, geology, and education, have been making movies that have proved of great use in scientific talks, media interviews, and education. Thus, SCEC UseIT incorporates a wide variety of scientific and human resources to create products of value to the scientific and outreach communities. The program plans to continue with its interdisciplinary approach, increasing the relevance of the

  5. Geriatric resources in acute care hospitals and trauma centers: a scarce commodity.

    Science.gov (United States)

    Maxwell, Cathy A; Mion, Lorraine C; Minnick, Ann

    2013-12-01

    The number of older adults admitted to acute care hospitals with traumatic injury is rising. The purpose of this study was to examine the location of five prominent geriatric resource programs in U.S. acute care hospitals and trauma centers (N = 4,865). As of 2010, 5.8% of all U.S. hospitals had at least one of these programs. Only 8.8% of trauma centers were served by at least one program; the majorities were in level I trauma centers. Slow adoption of geriatric resource programs in hospitals may be due to lack of champions who will advocate for these programs, lack of evidence of their impact on outcomes, or lack of a business plan to support adoption. Future studies should focus on the benefits of geriatric resource programs from patients' perspectives, as well as from business case and outcomes perspectives. Copyright 2013, SLACK Incorporated.

  6. MonitoringResources.org—Supporting coordinated and cost-effective natural resource monitoring across organizations

    Science.gov (United States)

    Bayer, Jennifer M.; Scully, Rebecca A.; Weltzin, Jake F.

    2018-05-21

    Natural resource managers who oversee the Nation’s resources require data to support informed decision-making at a variety of spatial and temporal scales that often cross typical jurisdictional boundaries such as states, agency regions, and watersheds. These data come from multiple agencies, programs, and sources, often with their own methods and standards for data collection and organization. Coordinating standards and methods is often prohibitively time-intensive and expensive. MonitoringResources.org offers a suite of tools and resources that support coordination of monitoring efforts, cost-effective planning, and sharing of knowledge among organizations. The website was developed by the Pacific Northwest Aquatic Monitoring Partnership—a collaboration of Federal, state, tribal, local, and private monitoring programs—and the U.S. Geological Survey (USGS), with funding from the Bonneville Power Administration and USGS. It is a key component of a coordinated monitoring and information network.

  7. Thermoluminescence responses of photon- and electron-irradiated lithium potassium borate co-doped with Cu+Mg or Ti+Mg

    International Nuclear Information System (INIS)

    Alajerami, Y.S.M.; Hashim, S.; Ramli, A.T.; Saleh, M.A.; Saripan, M.I.; Alzimami, K.; Min Ung, Ngie

    2013-01-01

    New glasses Li 2 CO 3 –K 2 CO 3 –H 3 BO 3 (LKB) co-doped with CuO and MgO, or with TiO 2 and MgO, were synthesized by the chemical quenching technique. The thermoluminescence (TL) responses of LKB:Cu,Mg and LKB:Ti,Mg irradiated with 6 MV photons or 6 MeV electrons were compared in the dose range 0.5–4.0 Gy. The standard commercial dosimeter LiF:Mg,Ti (TLD-100) was used to calibrate the TL reader and as a reference in comparison of the TL properties of the new materials. The dependence of the responses of the new materials on 60 Co dose is linear in the range of 1–1000 Gy. The TL yields of both of the co-doped glasses and TLD-100 are greater for electron irradiation than for photon irradiation. The TL sensitivity of LKB:Ti,Mg is 1.3 times higher than the sensitivity of LKB:Cu,Mg and 12 times less than the sensitivity of TLD-100. The new TL dosimetric materials have low effective atomic numbers, good linearity of the dose responses, excellent signal reproducibility, and a simple glow curve structure. This combination of properties makes them suitable for radiation dosimetry. - Highlights: • Enhancement of about three times has been shown with the increment of MgO. • A comparison was carried out between the TL responses of the prepared dosimeters and TLD-100. • The prepared dosimeters show simple glow curve, low Z material and excellent reproducibility. • The TL measurements show a linear dose response in a long span of exposures. • The electron response shows 1.18 times greater than photon response for the prepared dosimeters

  8. Endangered species and cultural resources program, Naval Petroleum Reserves in California: Annual report FY95

    International Nuclear Information System (INIS)

    1996-04-01

    In FY95, EG and G Energy Measurements, Inc. (EG and G/EM) continued to support efforts to protect endangered species and cultural resources at the Naval Petroleum Reserves in California (NPRC). These efforts are conducted to ensure NPRC compliance with regulations regarding the protection of listed species and cultural resources on Federal properties. Population monitoring activities are conducted annually for San Joaquin kit foxes, giant kangaroo rats, blunt-nosed leopard lizards, and Hoover's wooly-star. To mitigate impacts of oil field activities on listed species, 674 preactivity surveys covering approximately 211 hectares (521 acres) were conducted in FY95. EG and G/EM also assisted with mitigating effects from third-party projects, primarily by conducting biological and cultural resource consultations with regulatory agencies. EG and G/EM has conducted an applied habitat reclamation program at NPRC since 1985. In FY95, an evaluation of revegetation rates on reclaimed and non-reclaimed disturbed lands was completed, and the results will be used to direct future habitat reclamation efforts at NPRC. In FY95, reclamation success was monitored on 50 sites reclaimed in 1985. An investigation of factors influencing the distribution and abundance of kit foxes at NPRC was initiated in FY94. Factors being examined include habitat disturbance, topography, grazing, coyote abundance, lagomorph abundance, and shrub density. This investigation continued in FY95 and a manuscript on this topic will be completed in FY96. Also, Eg and G/EM completed collection of field data to evaluate the effects of a well blow-out on plant and animal populations. A final report will be prepared in FY96. Finally, EG and G/EM completed a life table analysis on San Joaquin kit foxes at NPRC

  9. State Electricity Regulatory Policy and Distributed Resources: Accommodating Distributed Resources in Wholesale Markets

    Energy Technology Data Exchange (ETDEWEB)

    Weston, F.; Harrington, C.; Moskovitz, D.; Shirley, W.; Cowart, R.; Sedano, R.

    2002-10-01

    Distributed resources can provide cost-effective reliability and energy services - in many cases, obviating the need for more expensive investments in wires and central station electricity generating facilities. Given the unique features of distributed resources, the challenge facing policymakers today is how to restructure wholesale markets for electricity and related services so as to reveal the full value that distributed resources can provide to the electric power system (utility grid). This report looks at the functions that distributed resources can perform and examines the barriers to them. It then identifies a series of policy and operational approaches to promoting DR in wholesale markets. This report is one in the State Electricity Regulatory Policy and Distributed Resources series developed under contract to NREL (see Annual Technical Status Report of the Regulatory Assistance Project: September 2000-September 2001, NREL/SR-560-32733). Other titles in this series are: (1) Distributed Resource Distribution Credit Pilot Programs - Revealing the Value to Consumers and Vendors, NREL/SR-560-32499; (2) Distributed Resources and Electric System Reliability, NREL/SR-560-32498; (3) Distribution System Cost Methodologies for Distributed Generation, NREL/SR-560-32500; (4) Distribution System Cost Methodologies for Distributed Generation Appendices, NREL/SR-560-32501

  10. Natural resource damage assessments: Linking injury to restoration

    International Nuclear Information System (INIS)

    Newell, M.; Collinson-Kahl, C.

    1993-01-01

    Under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the Oil Pollution Act of 1990 (OPA 90), natural resource trustees have the authority to act on behalf of the public to file claims for damages against potentially responsible parties for injury to, destruction of, or loss of natural resources and related human services caused by releases of hazardous substances or discharges of oil. Damages recovered must be used to restore, replace, or acquire the equivalent of such resources. Therefore, to adequately restore an injured resource and the services it provides, a natural resource restoration proposal should address, as directly as possible, the injuries caused by a hazardous substance release. In other words, the resources restored and services generated by the restoration activities should be commensurate in type and amount with the reduction in services caused by the release. More specifically, the natural resource damage assessment regulations indicate that services should be used as the common currency for linking injury to restoration. The following conceptual steps may be followed to develop a primary restoration program that is linked to the injuries: Define the resources that were injured, and identify the services provided by those resources that were reduced by the injury. Define the baseline levels of the quantity of the resource, and the quantity of the services that would have been provided by the resource if the injury had not occurred. Quantify the interim lost value, which represents the reduction in services (compared to a baseline) from the time of the injury through the time of full recovery of the resources, assuming natural recovery. Evaluate the potential restoration projects for inclusion in the primary restoration program, which is designed to accelerate and enhance natural recovery of the resources and the flow of services from the resources

  11. Ostomy Home Skills Program

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  12. Evaluation: theoretical underpinnings and web resources.

    Science.gov (United States)

    Berryman, Donna R

    2012-01-01

    Librarians may benefit from understanding research theory more fully, looking at the services they offer as a program, and using program evaluation to understand the program value more completely. The process of program evaluation is research, and, as such, it should be situated within theory. This article reviews two of the basic theoretical concepts of research: ontology and epistemology. These concepts work together to help craft the research questions, and the questions drive the selection of methodology. The article also provides a list of web resources useful for understanding research theory in evaluation.

  13. A resource facility for kinetic analysis: modeling using the SAAM computer programs.

    Science.gov (United States)

    Foster, D M; Boston, R C; Jacquez, J A; Zech, L

    1989-01-01

    Kinetic analysis and integrated system modeling have contributed significantly to understanding the physiology and pathophysiology of metabolic systems in humans and animals. Many experimental biologists are aware of the usefulness of these techniques and recognize that kinetic modeling requires special expertise. The Resource Facility for Kinetic Analysis (RFKA) provides this expertise through: (1) development and application of modeling technology for biomedical problems, and (2) development of computer-based kinetic modeling methodologies concentrating on the computer program Simulation, Analysis, and Modeling (SAAM) and its conversational version, CONversational SAAM (CONSAM). The RFKA offers consultation to the biomedical community in the use of modeling to analyze kinetic data and trains individuals in using this technology for biomedical research. Early versions of SAAM were widely applied in solving dosimetry problems; many users, however, are not familiar with recent improvements to the software. The purpose of this paper is to acquaint biomedical researchers in the dosimetry field with RFKA, which, together with the joint National Cancer Institute-National Heart, Lung and Blood Institute project, is overseeing SAAM development and applications. In addition, RFKA provides many service activities to the SAAM user community that are relevant to solving dosimetry problems.

  14. HANFORD TANK FARM RESOURCE CONSERVATION and RECOVERY ACT (RCRA) CORRECTIVE ACTION PROGRAM

    International Nuclear Information System (INIS)

    KRISTOFZSKI, J.G.

    2007-01-01

    As a consequence of producing special nuclear material for the nation's defense, large amounts of extremely hazardous radioactive waste was created at the US Department of Energy's (DOE) Hanford Site in south central Washington State. A little over 50 million gallons of this waste is now stored in 177 large, underground tanks on Hanford's Central Plateau in tank farms regulated under the Atomic Energy Act and the Resource, Conservation, and Recovery Act (RCRA). Over 60 tanks and associated infrastructure have released or are presumed to have released waste in the vadose zone. In 1998, DOE's Office of River Protection established the Hanford Tank Farm RCRA Corrective Action Program (RCAP) to: (1) characterize the distribution and extent of the existing vadose zone contamination; (2) determine how the contamination will move in the future; (3) estimate the impacts of this contamination on groundwater and other media; (4) develop and implement mitigative measures; and (5) develop corrective measures to be implemented as part of the final closure of the tank farm facilities. Since its creation, RCAP has made major advances in each of these areas, which will be discussed in this paper

  15. Ostomy Home Skills Program

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  16. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Safety Resources About the Patient Education Program The Recovery Room Choosing Wisely Educational Programs Educational Programs Educational ... and practice the skills needed for optimal postoperative recovery. The kit supports the entire surgical team with ...

  17. Ostomy Home Skills Program

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    Full Text Available ... and Safety Inspiring Quality Initiative Resources Continuous Quality Improvement ACS Clinical Scholars in Residence AHRQ Safety Program ... Enrollment Webinars ACS NSQIP ACS National Surgical Quality Improvement Program ACS National Surgical Quality Improvement Program About ...

  18. Energy resource management for energy-intensive manufacturing industries

    Energy Technology Data Exchange (ETDEWEB)

    Brenner, C.W.; Levangie, J.

    1981-10-01

    A program to introduce energy resource management into an energy-intensive manufacturing industry is presented. The food industry (SIC No. 20) was chosen and 20 companies were selected for interviews, but thirteen were actually visited. The methodology for this program is detailed. Reasons for choosing the food industry are described. The substance of the information gained and the principal conclusions drawn from the interviews are given. Results of the model Energy Resource Management Plan applied to three companies are compiled at length. Strategies for dissemination of the information gained are described. (MCW)

  19. Actionable Science in the Gulf of Mexico: Connecting Researchers and Resource Managers

    Science.gov (United States)

    Lartigue, J.; Parker, F.; Allee, R.; Young, C.

    2017-12-01

    The National Oceanic and Atmospheric Administration (NOAA) RESTORE Science Program was established in the wake of the Deepwater Horizon oil spill to to carry out research, observation, and monitoring to support the long-term sustainability of the Gulf of Mexico ecosystem, including its fisheries. Administered in partnership with the US Fish and Wildlife Service, the Science Program emphasizes a connection between science and decision-making. This emphasis translated into an engagement process that allowed for resource managers and other users of information about the ecosystem to provide direct input into the science plan for the program. In developing funding opportunities, the Science Program uses structured conversations with resource managers and other decision makers to focus competitions on specific end user needs. When evaluating proposals for funding, the Science Program uses criteria that focus on applicability of a project's findings and products, end user involvement in project planning, and the approach for transferring findings and products to the end user. By including resource managers alongside scientific experts on its review panels, the Science Program ensures that these criteria are assessed from both the researcher and end user perspectives. Once funding decisions are made, the Science Program assigns a technical monitor to each award to assist with identifying and engaging end users. Sharing of best practices among the technical monitors has provided the Science Program insight on how best to bridge the gap between research and resource management and how to build successful scientist-decision maker partnerships. During the presentation, we will share two case studies: 1) design of a cooperative (fisheries scientist, fisheries managers, and fishers), Gulf-wide conservation and monitoring program for fish spawning aggregations and 2) development of habitat-specific ecosystem indicators for use by federal and state resource managers.

  20. Evaluation and Ranking of Geothermal Resources for Electrical Generation or Electrical Offset in Idaho, Montana, Oregon and Washington. Volume II.

    Energy Technology Data Exchange (ETDEWEB)

    Bloomquist, R. Gordon

    1985-06-01

    This volume contains appendices on: (1) resource assessment - electrical generation computer results; (2) resource assessment summary - direct use computer results; (3) electrical generation (high temperature) resource assessment computer program listing; (4) direct utilization (low temperature) resource assessment computer program listing; (5) electrical generation computer program CENTPLANT and related documentation; (6) electrical generation computer program WELLHEAD and related documentation; (7) direct utilization computer program HEATPLAN and related documentation; (8) electrical generation ranking computer program GEORANK and related documentation; (9) direct utilization ranking computer program GEORANK and related documentation; and (10) life cycle cost analysis computer program and related documentation. (ACR)

  1. ANALISIS KESIAPAN PROGRAM STUDI DALAM PRODUCTION BASED EDUCATION: STUDI PADA PROGRAM STUDI D3 AKUNTANSI POLINES

    Directory of Open Access Journals (Sweden)

    Muhammad Noor Ardiansah

    2015-03-01

    Full Text Available There has been no clear studies to identify, verify and analyze readiness program resources in order to study the implementation of PBE resulted in initial position (existing point is not clear that the priority programs and activities that are carried out per year tend to be responsive and not directed priorities. These conditions resulted in analysis of resource readiness courses in the management of production-based learning pattern PBE draw conducted This study aims to identify and verify and analyze readiness resources management courses in the pattern of production based learning, particularly in the Accounting Studies Program. This research is expected to be used to increase the effectiveness of learning and vocational education to improve the quality and relevance of polytechnic graduates. Total score was 33 the existence of resources from the scale of 12-60. The average score is 2.75. The average score was shown the position of Prodi's resources have been used, but its role is unclear (repeatable tend to have clearly defined functions, communicated and documented (defined. Resources have been managed, monitored and evaluated well (managed are: curriculum resources, networking courses, lab facilities, ISO-based management. Resources have been used but not optimal role: resources module practice, the formulation of an internship, practice material / TA, the performance of IC-based lecturer

  2. ANALISIS KESIAPAN PROGRAM STUDI DALAM PRODUCTION BASED EDUCATION: STUDI PADA PROGRAM STUDI D3 AKUNTANSI POLINES

    Directory of Open Access Journals (Sweden)

    Muhammad Noor Ardiansah

    2014-06-01

    Full Text Available There has been no clear studies to identify, verify and analyze readiness program resources in order to study the implementation of PBE resulted in initial position (existing point is not clear that the priority programs and activities that are carried out per year tend to be responsive and not directed priorities. These conditions resulted in analysis of resource readiness courses in the management of production-based learning pattern PBE draw conducted This study aims to identify and verify and analyze readiness resources management courses in the pattern of production based learning, particularly in the Accounting Studies Program. This research is expected to be used to increase the effectiveness of learning and vocational education to improve the quality and relevance of polytechnic graduates. Total score was 33 the existence of resources from the scale of 12-60. The average score is 2.75. The average score was shown the position of Prodi's resources have been used, but its role is unclear (repeatable tend to have clearly defined functions, communicated and documented (defined. Resources have been managed, monitored and evaluated well (managed are: curriculum resources, networking courses, lab facilities, ISO-based management. Resources have been used but not optimal role: resources module practice, the formulation of an internship, practice material / TA, the performance of IC-based lecturer

  3. Mitigating Negative Externalities Affecting Access and Equity of Education in Low-Resource Countries: A Study Exploring Social Marketing as a Potential Strategy for Planning School Food Programs in Malawi

    Science.gov (United States)

    Magreta-Nyongani, Martha

    2012-01-01

    School feeding programs enhance the efficiency of the education system by improving enrollment, reducing dropouts and increasing perseverance. They also have the potential to reach the poor, directly making them an effective social safety net. In many low-resource countries, school feeding programs are designed to protect children from the effects…

  4. Ecological and environmental data as under-utilized national resources: results of the TIE/ACCESS program

    Energy Technology Data Exchange (ETDEWEB)

    Armentano, T.V.; Loucks, O.L.

    1979-06-01

    The goal of The Institute of Energy (TIE) 1977 to 1979 ACCESS program was to define the national need for ecological and environmental data and the extent to which present data documentation and archiving are meeting this need. The principal steps focussed on current data documentation and research in government, private and academic sectors of the natural science technical community, particularly as they bear on the accessibility of environmental data to secondary users. The extent to which existing data services are satisfying the needs of data users also was emphasized. The results indicate that the potential contributions which existing data and models could make are not being achieved because of inconsistencies in data documentation, inadequate communication between data suppliers and data users, and a lack of overall coordination of the data bases in national research and monitoring programs. A nationally coordinated network is proposed which focuses on regional data centers and ties together the hierarchy of data bases (national, state, and local) with the broad spectrum of potential users. The network concept includes immediate development of a comprehensive catalog of data resources in each region, with later production of a data abstract journal as one of two methods for communicating between regional and local data centers and the user community.

  5. SPA AND CLIMATIC RESORTS (CENTERS AS RESOURCES OF PROGRAM OF SPORT RECREATION IMPLEMENTATION

    Directory of Open Access Journals (Sweden)

    Ivica Nikolić

    2006-06-01

    Full Text Available The aspiration of the civilized man is the improvement of work which aim is to achieve as big as possible effect of productivity and as small as possible participation of labour. The result of this process, which cannot be avoided, is some kind of fatigue that has hypocinaesiological characteristics in regard to demands of modern work process. The most effective way to fight against fatigue is to have an active holiday that is meaningfully programmed, led and carried out through movement of tourists, with the addition of natural factors, among which climate and healing waters are particularly important. These very resources characterize the tourist potential of Serbia and Montenegro with lots of available facilities at 1000 m height above the sea level and spa centers with springs and a complete offer physio-prophylactic procedures and following facilities for sport recreation. The implementation of programmed active holidays in to the corpus of tourist offer of Serbia and Montenegro represents prospective of development of tourism and tourist economy with effects of multiple importance as for participants, so for the level of tourist consumption. That will definitely influence the lengthening of tourist season as the primary goal of every catering establishment. Surveys show that the affection and viewpoints of potential tourists are especially directed towards engaging sport games and activities on and in the water, as part of the elementary tourist offer in spas and climatic resorts and their available facilities. Recommendationsand postulates of program of sport recreation, which are presented through four charts, are the basis of marketing strategy of appearance on tourist market with permanent education of management personnel and further research of potential market expanding. The publication and distribution of advertising materials are especially important, both at the market in our country and at the foreign market, where the abundance

  6. Assessing U.S. coal resources and reserves

    Science.gov (United States)

    Shaffer, Brian N.

    2017-09-27

    The U.S. Coal Resources and Reserves Assessment Project, as part of the U.S. Geological Survey (USGS) Energy Resources Program, conducts systematic, geology-based, regional assessments of significant coal beds in major coal basins in the United States. These assessments detail the quantity, quality, location, and economic potential of the Nation’s remaining coal resources and reserves and provide objective scientific information that assists in the formulation of energy strategies, environmental policies, land-use management practices, and economic projections.

  7. Ostomy Home Skills Program

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    Full Text Available ... Quality and Safety Inspiring Quality Initiative Resources Continuous Quality Improvement ACS Clinical Scholars in Residence AHRQ Safety Program ... ISCR Enrollment Webinars ACS NSQIP ACS National Surgical Quality Improvement Program ACS National Surgical Quality Improvement Program About ...

  8. Mexico Wind Resource Assessment Project

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, M.N.; Elliott, D.L.

    1995-05-01

    A preliminary wind energy resource assessment of Mexico that produced wind resource maps for both utility-scale and rural applications was undertaken as part of the Mexico-U.S. Renewable Energy Cooperation Program. This activity has provided valuable information needed to facilitate the commercialization of small wind turbines and windfarms in Mexico and to lay the groundwork for subsequent wind resource activities. A surface meteorological data set of hourly data in digital form was utilized to prepare a more detailed and accurate wind resource assessment of Mexico than otherwise would have been possible. Software was developed to perform the first ever detailed analysis of the wind characteristics data for over 150 stations in Mexico. The hourly data set was augmented with information from weather balloons (upper-air data), ship wind data from coastal areas, and summarized wind data from sources in Mexico. The various data were carefully evaluated for their usefulness in preparing the wind resource assessment. The preliminary assessment has identified many areas of good-to-excellent wind resource potential and shows that the wind resource in Mexico is considerably greater than shown in previous surveys.

  9. Status of mineral resources evaluation and forecast

    International Nuclear Information System (INIS)

    Ma Hanfeng; Li Ziying; Luo Yi; Li Shengxiang; Sun Wenpeng

    2007-01-01

    The work of resources evaluation and forecast is a focus to the governments of every country in the world, it is related to the establishment of strategic policy on the national mineral resources. In order to quantitatively evaluate the general potential of uranium resources in China and better forecast uranium deposits, this paper briefly introduces the method of evaluating total amount of mineral resources, especially 6 usual prospective methods which are recommended in international geology comparison programs, as well as principle of usual mineral resources quantitative prediction and its steps. The work history of mineral resources evaluation and forecast is reviewed concisely. Advantages and disadvantages of each method, their application field and condition are also explained briefly. At last, the history of uranium resources evaluation and forecast in China and its status are concisely outlined. (authors)

  10. Identification and comparison of predictive models of rectal and bladder toxicity in the case of prostatic irradiation; Identification et comparaison de modeles predictifs de toxicite rectale et vesicale en cas d'irradiation prostatique

    Energy Technology Data Exchange (ETDEWEB)

    Gnep, K.; Chira, C.; Le Prise, E.; Crevoisier, R. de [Centre Eugene-Marquis, Rennes (France); Zhu, J.; Simon, A.; Ospina Arango, J.D. [Inserm U642, Rennes (France); Messai, T.; Bossi, A. [Institut Gustave-Roussy, Villejuif (France); Beckendorf, V. [Centre Alexis-Vautrin, Nancy (France)

    2011-10-15

    More than 400 patients have been treated by conformational radiation therapy for a localized prostate adenocarcinoma and some have been selected according to the availability of dose-volume histograms. Predictive models of rectal and bladder toxicity have been compared: LKB, Logit EUD and Poisson EUD for rectal toxicity, LKB, Logit EUD, Poisson EUD and Schultheiss for bladder toxicity. Results suggest that these models could be used during the inverse planning of intensity-modulated radiation therapy in order to decrease toxicity. Short communication

  11. 76 FR 28210 - Eastern Arizona Counties Resource Advisory Committee

    Science.gov (United States)

    2011-05-16

    ... DEPARTMENT OF AGRICULTURE Forest Service Eastern Arizona Counties Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Eastern Arizona Counties will meet...: Julia Faith Rivera, RAC Program Manager, Eastern Arizona Counties Resource Advisory Committee, Apache...

  12. Partnerships in natural resource agencies: a conceptual framework

    Science.gov (United States)

    Catherine V. Darrow; Jerry J. Vaske

    1995-01-01

    To meet financial constraints while maintaining or improving programs, natural resource managers have increasingly turned to partnerships with other public agencies or private businesses. The process of developing a successful partnership, however, is rarely chronicled, much less empirically studied. By using the available natural resource and business management...

  13. Analysis of problem solving on project based learning with resource based learning approach computer-aided program

    Science.gov (United States)

    Kuncoro, K. S.; Junaedi, I.; Dwijanto

    2018-03-01

    This study aimed to reveal the effectiveness of Project Based Learning with Resource Based Learning approach computer-aided program and analyzed problem-solving abilities in terms of problem-solving steps based on Polya stages. The research method used was mixed method with sequential explanatory design. The subject of this research was the students of math semester 4. The results showed that the S-TPS (Strong Top Problem Solving) and W-TPS (Weak Top Problem Solving) had good problem-solving abilities in each problem-solving indicator. The problem-solving ability of S-MPS (Strong Middle Problem Solving) and (Weak Middle Problem Solving) in each indicator was good. The subject of S-BPS (Strong Bottom Problem Solving) had a difficulty in solving the problem with computer program, less precise in writing the final conclusion and could not reflect the problem-solving process using Polya’s step. While the Subject of W-BPS (Weak Bottom Problem Solving) had not been able to meet almost all the indicators of problem-solving. The subject of W-BPS could not precisely made the initial table of completion so that the completion phase with Polya’s step was constrained.

  14. Energy Resources Performance Report, FY 1991 and FY 1992.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1993-07-01

    Once the Federal Columbia River Power System provided all the power our customers needed and surplus energy, which we sold to others. However, we planned for the time when the surplus would disappear. With our customers, we developed centralized, region-wide conservation programs to conserve energy and build the knowledge and ability to save more energy when needed. We began to look at conservation as a resource, comparing it with supply-side alternatives. Much was accomplished. In Bonneville`s service area in the 1980s, our customers acquired 300 average megawatts (aMW) of conservation savings. How? By weatherizing about 240,000 homes, by making aluminum plants, other industrial plants and commercial buildings more efficient, and also by encouraging states to adopt energy-efficient building codes. Now, our energy surplus is gone. Our customers need energy, and in a hurry. While we plan how much energy will be needed, when and by which customers, we must concurrently accelerate our efforts to acquire resources. Our 1990 Resource Program launched a strategy to do just that, starting in 1991 and 1992, with continuing activities in 1993--1995. The goals and plans of the 1990 Resource Program are still being implemented.

  15. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... to Be a Surgeon Resident Resources Teaching Resources Online Guide to Choosing a Surgical Residency Practice Management Workshops Patients and Family Patient Education Patient Education Patients Medical Professionals Skills Programs Find ...

  16. Web-based resources for critical care education.

    Science.gov (United States)

    Kleinpell, Ruth; Ely, E Wesley; Williams, Ged; Liolios, Antonios; Ward, Nicholas; Tisherman, Samuel A

    2011-03-01

    To identify, catalog, and critically evaluate Web-based resources for critical care education. A multilevel search strategy was utilized. Literature searches were conducted (from 1996 to September 30, 2010) using OVID-MEDLINE, PubMed, and the Cumulative Index to Nursing and Allied Health Literature with the terms "Web-based learning," "computer-assisted instruction," "e-learning," "critical care," "tutorials," "continuing education," "virtual learning," and "Web-based education." The Web sites of relevant critical care organizations (American College of Chest Physicians, American Society of Anesthesiologists, American Thoracic Society, European Society of Intensive Care Medicine, Society of Critical Care Medicine, World Federation of Societies of Intensive and Critical Care Medicine, American Association of Critical Care Nurses, and World Federation of Critical Care Nurses) were reviewed for the availability of e-learning resources. Finally, Internet searches and e-mail queries to critical care medicine fellowship program directors and members of national and international acute/critical care listserves were conducted to 1) identify the use of and 2) review and critique Web-based resources for critical care education. To ensure credibility of Web site information, Web sites were reviewed by three independent reviewers on the basis of the criteria of authority, objectivity, authenticity, accuracy, timeliness, relevance, and efficiency in conjunction with suggested formats for evaluating Web sites in the medical literature. Literature searches using OVID-MEDLINE, PubMed, and the Cumulative Index to Nursing and Allied Health Literature resulted in >250 citations. Those pertinent to critical care provide examples of the integration of e-learning techniques, the development of specific resources, reports of the use of types of e-learning, including interactive tutorials, case studies, and simulation, and reports of student or learner satisfaction, among other general

  17. A real-time Java tool chain for resource constrained platforms

    DEFF Research Database (Denmark)

    Korsholm, Stephan Erbs; Søndergaard, Hans; Ravn, Anders P.

    2013-01-01

    The Java programming language was originally developed for embedded systems, but the resource requirements of previous and current Java implementations - especially memory consumption - tend to exclude them from being used on a significant class of resource constrained embedded platforms. The con......The Java programming language was originally developed for embedded systems, but the resource requirements of previous and current Java implementations - especially memory consumption - tend to exclude them from being used on a significant class of resource constrained embedded platforms...... by integrating: (1) a lean virtual machine (HVM) without any external dependencies on POSIX-like libraries or other OS functionalities, (2) a hardware abstraction layer, implemented almost entirely in Java through the use of hardware objects, first level interrupt handlers, and native variables, and (3....... An evaluation of the presented solution shows that the miniCDj benchmark gets reduced to a size where it can run on resource constrained platforms....

  18. GPSR: A Resource for Genomics Proteomics and Systems Biology

    Indian Academy of Sciences (India)

    GPSR: A Resource for Genomics Proteomics and Systems Biology · Simple Calculation Programs for Biology Immunological Methods · Simple Calculation Programs for Biology Methods in Molecular Biology · Simple Calculation Programs for Biology Other Methods · PowerPoint Presentation · Slide 6 · Slide 7 · Prediction of ...

  19. Resource management in utility and cloud computing

    CERN Document Server

    Zhao, Han

    2013-01-01

    This SpringerBrief reviews the existing market-oriented strategies for economically managing resource allocation in distributed systems. It describes three new schemes that address cost-efficiency, user incentives, and allocation fairness with regard to different scheduling contexts. The first scheme, taking the Amazon EC2? market as a case of study, investigates the optimal resource rental planning models based on linear integer programming and stochastic optimization techniques. This model is useful to explore the interaction between the cloud infrastructure provider and the cloud resource c

  20. Crab Rationalization Permit Program

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Crab Rationalization Program (Program) allocates BSAI crab resources among harvesters, processors, and coastal communities. The North Pacific Fishery Management...

  1. Human resources for health strategies adopted by providers in resource-limited settings to sustain long-term delivery of ART: a mixed-methods study from Uganda.

    Science.gov (United States)

    Zakumumpa, Henry; Taiwo, Modupe Oladunni; Muganzi, Alex; Ssengooba, Freddie

    2016-10-19

    Human resources for health (HRH) constraints are a major barrier to the sustainability of antiretroviral therapy (ART) scale-up programs in Sub-Saharan Africa. Many prior approaches to HRH constraints have taken a top-down trend of generalized global strategies and policy guidelines. The objective of the study was to examine the human resources for health strategies adopted by front-line providers in Uganda to sustain ART delivery beyond the initial ART scale-up phase between 2004 and 2009. A two-phase mixed-methods approach was adopted. In the first phase, a survey of a nationally representative sample of health facilities (n = 195) across Uganda was conducted. The second phase involved in-depth interviews (n = 36) with ART clinic managers and staff of 6 of the 195 health facilities purposively selected from the first study phase. Quantitative data was analysed based on descriptive statistics, and qualitative data was analysed by coding and thematic analysis. The identified strategies were categorized into five themes: (1) providing monetary and non-monetary incentives to health workers on busy ART clinic days; (2) workload reduction through spacing ART clinic appointments; (3) adopting training workshops in ART management as a motivation strategy for health workers; (4) adopting non-physician-centred staffing models; and (5) devising ART program leadership styles that enhanced health worker commitment. Facility-level strategies for responding to HRH constraints are feasible and can contribute to efforts to increase country ownership of HIV programs in resource-limited settings. Consideration of the human resources for health strategies identified in the study by ART program planners and managers could enhance the long-term sustainment of ART programs by providers in resource-limited settings.

  2. Uranium resources in the United States

    International Nuclear Information System (INIS)

    Grenon, Michel.

    1975-01-01

    The United States are certainly the country which is the most concerned by a better evaluation of uranium resources. This is so because of the importance of the American nuclear program and because of a certain number of doubts in their uranium supply. This is probably why studies concerning American uranium resources have been very frequent in recent months. Although, most of these studies are not yet finished it is perhaps possible to draw a few conclusions in order to better see the framework of this important uranium resources problem. This is what this article attempts, using among other studies, the one carried-out for the National Science Foundation which is among the most complete, especially concerning the complete range of resources [fr

  3. Effects of an emergency medical services-based resource access program on frequent users of health services.

    Science.gov (United States)

    Tadros, Anthony S; Castillo, Edward M; Chan, Theodore C; Jensen, Anne Marie; Patel, Ekta; Watts, Kerin; Dunford, James V

    2012-01-01

    A small group of adults disproportionately and ineffectively use acute services including emergency medical services (EMS) and emergency departments (EDs). The resulting episodic, uncoordinated care is of lower quality and higher cost and simultaneously consumes valuable public safety and acute care resources. To address this issue, we measured the impact of a pilot, EMS-based case management and referral intervention termed the San Diego Resource Access Program (RAP) to reduce EMS, ED, and inpatient (IP) visits. This was a historical cohort study of RAP records and billing data of EMS and one urban hospital for 51 individuals sequentially enrolled in the program. The study sample consisted of adults with ≥ 10 EMS transports within 12 months and others reported by prehospital personnel with significant recent increases in transports. Data were collected over a 31-month time period from December 2006 to June 2009. Data were collected for equal pre- and postenrollment time periods based on date of initial RAP contact, and comparisons were made using the Wilcoxon signed-rank test. Overall use for subjects is reported. The majority of subjects were male (64.7%), homeless (58.8%), and 40 to 59 years of age (72.5%). Between the pre and post periods, EMS encounters declined 37.6% from 736 to 459 (p = 0.001), resulting in a 32.1% decrease in EMS charges from $689,743 to $468,394 (p = 0.004). The EMS task time and mileage decreased by 39.8% and 47.5%, respectively, accounting for 262 (p = 0.008) hours and 1,940 (p = 0.006) miles. The number of ED encounters at the one participating hospital declined 28.1% from 199 to 143, which correlated with a 12.7% decrease in charges from $413,410 to $360,779. The number of IP admissions declined by 9.1% from 33 to 30, corresponding to a 5.9% decrease in IP charges from $687,306 to $646,881. Hospital length of stay declined 27.9%, from 122 to 88 days. Across all services, total charges declined by $314,406. This pilot study

  4. Dutchess County Resource Recovery Task Force report: Dutchess County Pyrolysis Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    Dutchess County initiated development of a long-range master plan for Solid Waste Management in 1971. The plan included development of a resource recovery facility to service the municipalities in the County population center. Based on early recommendations, a pyrolysis facility employing Purox technology was to be implemented. A feasibility study, paid for by County funds was completed in 1975. The study provided siting recommendations, estimation of available waste, and preliminary facility design. Because of various considerations, the project was not developed. Under the Department of Energy grant, the County reassessed the feasibility of a resource recovery facility, with emphasis on confirming previous conclusions supporting the Purox technology, waste availability, energy recovery and sale and siting of the plant. The conclusions reached in the new study were: a resource recovery facility is feasible for the County; sufficient waste for such a facility is available and subject to control; While Purox technology was feasible it is not the most appropriate available technoloy for the County; that mass burning with steam recovery is the most appropriate technology; and that resource recovery while presently more expensive than landfilling, represents the only cost effective, energy efficient, and environmentally sound way to handle the solid waste problem in the County.

  5. Involvement of Higher Education in Building Human Resources Character in the Era of Globalization

    Science.gov (United States)

    Ishomuddin

    2015-01-01

    In general, the objectives of this study were to explain the role played by universities in improving its human resources are office holders, lecturers, and students, explain the program what is being done related to the improvement of human resources, and explains the non-academic program to support the implementation of a program that has been…

  6. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... You Want to Be a Surgeon Resident Resources Teaching Resources Online Guide to Choosing a Surgical Residency Practice Management Workshops Patients and Family Patient Education Patient Education Patients Medical Professionals Skills Programs Find ...

  7. Strategic Human Resources Management of Employer Cooperative Education Programs.

    Science.gov (United States)

    Nielsen, Richard P.; Porter, Ralph C.

    1982-01-01

    This article discusses effective strategic planning and management of employer cooperative education programs. It examines types of planning, the need for such programs, and implementation strategies. Several case studies are considered: Dayton-Hudson, IBM, AT&T, Delta Airlines, and Rockwell International. (CT)

  8. Missouri Department of Natural Resources Hazardous Waste Program Weldon Spring site remedial action project. Status of project to date January 1996

    International Nuclear Information System (INIS)

    1998-01-01

    This document describes the progress made by the Missouri Department of Natural Resources during the third year (1995) of the Agreement in Support (AIS) in its oversight role at the Weldon Springs Site. The accomplishments this year include participation in several workgroup meetings, oversight of the two operable units (Groundwater and Quarry Residuals), coordination between the US DOE and the various regulatory programs, and continued independent analysis of the treated water discharges

  9. Development and Implementation of a Model Training Program to Assist Special Educators, Parks and Resource Management Personnel and Parents to Cooperatively Plan and Conduct Outdoor/Environmental Education Programs for Handicapped Children and Youth. Final Report.

    Science.gov (United States)

    Vinton, Dennis A.; Zachmeyer, Richard F.

    This final report presents a description of a 3-year project to develop and implement a model training program (for special education personnel, park and resource management personnel, and parents of disabled children) designed to promote outdoor environmental education for disabled children. The project conducted 22 training workshops (2-5 days)…

  10. The 2017 Space Resources Roundtable and New Space Resources Graduate Program at Colorado School of Mines

    Science.gov (United States)

    Abbud-Madrid, A.

    2017-10-01

    For eighteen years, SRR has brought together interested individuals from the space exploration community, the mining and minerals industries, and the financial sector to discuss issues related to the ISRU of lunar, asteroidal, and martian resources.

  11. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Communications to the Profession Advocacy Advocacy Overview Quality Payment Program QPP Resource Center QPP Resource Center 2018 ... Summary Letters on Health Care Reform Medicare Physician Payment Medical Liability Reform Opioids and Surgical Care GME ...

  12. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Program About ACS NSQIP Join ACS NSQIP Now Collaboratives Hospital Compare Quality and Safety Conference Participant Use ... You Want to Be a Surgeon Resident Resources Teaching Resources Online Guide to Choosing a Surgical Residency ...

  13. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... to Participate Resources Webinars for Young Surgeons YFA E-News YFA Advocacy Essay Contest Resident and Associate ... ACS Leader International Exchange Scholar Program Resources RAS E-News Medical Students Operation Giving Back Operation Giving ...

  14. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Quality ACS Leadership in Quality Setting the Quality Standard Optimal Resources for Surgical Quality and Safety Inspiring ... Clinical Data Registry Quality and Safety Conference Resources Standards Manual Contact Us Breast Disease National Accreditation Program ...

  15. Will Natural Resources Professionals Volunteer to Teach Youth?

    Science.gov (United States)

    Smith, Sanford S.; Finley, James C.; San Julian, Gary J.

    2010-01-01

    A unique approach to volunteer marketing research involved a mail survey with natural resources professionals from across Pennsylvania. Previous work identified this group as a source of potential volunteers for the 4-H youth natural resources program. The results give insights into those most likely to volunteer to teach youth through 4-H…

  16. Optimal design of distributed energy resource systems based on two-stage stochastic programming

    International Nuclear Information System (INIS)

    Yang, Yun; Zhang, Shijie; Xiao, Yunhan

    2017-01-01

    Highlights: • A two-stage stochastic programming model is built to design DER systems under uncertainties. • Uncertain energy demands have a significant effect on the optimal design. • Uncertain energy prices and renewable energy intensity have little effect on the optimal design. • The economy is overestimated if the system is designed without considering the uncertainties. • The uncertainty in energy prices has the significant and greatest effect on the economy. - Abstract: Multiple uncertainties exist in the optimal design of distributed energy resource (DER) systems. The expected energy, economic, and environmental benefits may not be achieved and a deficit in energy supply may occur if the uncertainties are not handled properly. This study focuses on the optimal design of DER systems with consideration of the uncertainties. A two-stage stochastic programming model is built in consideration of the discreteness of equipment capacities, equipment partial load operation and output bounds as well as of the influence of ambient temperature on gas turbine performance. The stochastic model is then transformed into its deterministic equivalent and solved. For an illustrative example, the model is applied to a hospital in Lianyungang, China. Comparative studies are performed to evaluate the effect of the uncertainties in load demands, energy prices, and renewable energy intensity separately and simultaneously on the system’s economy and optimal design. Results show that the uncertainties in load demands have a significant effect on the optimal system design, whereas the uncertainties in energy prices and renewable energy intensity have almost no effect. Results regarding economy show that it is obviously overestimated if the system is designed without considering the uncertainties.

  17. Effect of a Recently Completed Habitat Rehabilitation and Enhancement Project on Fish Abundance in La Grange Pool of the Illinois River Using Long Term Resource Monitoring Program Data

    National Research Council Canada - National Science Library

    O'Hara, Timothy M; McClelland, Michael A; Irons, Kevin S; Cook, Thad R; Sass, Greg G

    2008-01-01

    The Long Term Resource Monitoring Program (LTRMP) fish component monitors fish communities to test for changes in abundances and species composition in six regional trend areas of the Upper Mississippi River System...

  18. A real-time Java tool chain for resource constrained platforms

    DEFF Research Database (Denmark)

    Korsholm, Stephan E.; Søndergaard, Hans; Ravn, Anders Peter

    2014-01-01

    The Java programming language was originally developed for embedded systems, but the resource requirements of previous and current Java implementations – especially memory consumption – tend to exclude them from being used on a significant class of resource constrained embedded platforms. The con......The Java programming language was originally developed for embedded systems, but the resource requirements of previous and current Java implementations – especially memory consumption – tend to exclude them from being used on a significant class of resource constrained embedded platforms...... by integrating the following: (1) a lean virtual machine without any external dependencies on POSIX-like libraries or other OS functionalities; (2) a hardware abstraction layer, implemented almost entirely in Java through the use of hardware objects, first level interrupt handlers, and native variables; and (3....... An evaluation of the presented solution shows that the miniCDj benchmark gets reduced to a size where it can run on resource constrained platforms....

  19. Resource Conservation and Recovery Act Information (RCRAInfo)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Resource Conservation and Recovery Act Information (RCRAInfo) system contains information reported to the state environmental programs on activities and cleanup...

  20. Efforts for nuclear energy human resource development by industry-government-academic sectors cooperation. Nuclear Energy Human Resource Development Council Report

    International Nuclear Information System (INIS)

    Yamamoto, Shinji

    2009-01-01

    The report consists of eighteen sections such as the present conditions of nuclear energy, decreasing students in the department of technology and decreasing numbers of nuclear-related subjects, The Nuclear Energy Human Resources Development Program (HRD Program), The Nuclear Energy Human Resources Development Council (HRD Council), the industry-academia partnership for human resource development, the present situation of new graduates in the nuclear field, new workers of nuclear industry, the conditions of technical experts in the nuclear energy industry, long-range forecast of human resource, increasing international efforts, nuclear energy human resources development road map, three points for HRD, six basic subjects for HRD, the specific efforts of the industrial, governmental and academic sectors, promoting a better understanding of nuclear energy and supporting job hunting and employment, students to play an active part in the world, and support of the elementary and secondary schools. Change of numbers of nuclear-related subjects of seven universities, change of number of new graduates in nuclear field of various companies from 1985 to 2006, number of people employed by nuclear industries from 1998 to 2007, number of technical experts in the electric companies and the mining and manufacturing industries and forecast of number of technical experts in total nuclear industries are illustrated. (S.Y.)

  1. Factors that explain how policy makers distribute resources to mental health services.

    Science.gov (United States)

    Corrigan, Patrick W; Watson, Amy C

    2003-04-01

    Advocates hope to influence the resource allocation decisions of legislators and other policy makers to capture more resources for mental health programs. Findings from social psychological research suggest factors that, if pursued, may improve advocacy efforts. In particular, allocation decisions are affected by policy makers' perceptions of the scarcity of resources, effectiveness of specific programs, needs of people who have problems that are served by these programs, and extent of personal responsibility for these problems. These perceptions are further influenced by political ideology. Conservatives are motivated by a tendency to punish persons who are perceived as having personal responsibility for their problems by withholding resources, whereas liberals are likely to avoid tough allocation decisions. Moreover, these perceptions are affected by political accountability, that is, whether politicians perceive that their constituents will closely monitor their decisions. Just as the quality of clinical interventions improves when informed by basic research on human behavior, the efforts of mental health advocates will be advanced when they understand the psychological forces that affect policy makers' decisions about resources.

  2. NURE aerial gamma-ray and magnetic reconnaissance survey: NE Washington area, Okanogan NM 11-10, Sandpoint NM 11-11 Quadrangles. Volume I. Narrative report

    Energy Technology Data Exchange (ETDEWEB)

    1979-08-01

    As part of the Department of Energy (DOE) National Uranium Resource Evaluation (NURE) Program, LKB Resources, Inc. has performed a rotary-wing, reconnaissance high sensitivity radiometric and magnetic survey in north-east Washington. Three 1:250,000 scale NTMS quadrangles (Spokane, Sandpoint, and Okanogan) were surveyed. A total of 14,421 line miles (23,203 kilometers) of data were collected utilizing a Sikorsky S58T helicopter. Traverse lines were flown in an east-west direction at 1.0 and 3.0 mile (1.6 and 4.8 kilometers) spacing, with tie lines flown in a north-south direction at 12 mile (20 kilometer) spacing. The data were digitally recorded at 1.0 second intervals. The NaI terrestrial detectors used in this survey had a total volume of 2,154 cubic inches. The magnetometer employed was a modified ASQ-10 fluxgate system. This report covers only the Okanogan and Sandpoint 1:250,000 scale NTMS quadrangles. Spokane 1:250,000 scale NTMS quadrangle is covered in a separate report. The radiometric data were normalized to 400 feet terrain clearance. The data are presented in the form of computer listings on microfiche and as stacked profile plots. Profile plots are contained in Volume II of this report. A geologic interpretation of the radiometric and magnetic data is included as part of this report.

  3. NURE aerial gamma-ray and magnetic reconnaissance survey: NE Washington area, Okanogan NM 11-10, Sandpoint NM 11-11 Quadrangles. Volume I. Narrative report

    International Nuclear Information System (INIS)

    1979-08-01

    As part of the Department of Energy (DOE) National Uranium Resource Evaluation (NURE) Program, LKB Resources, Inc. has performed a rotary-wing, reconnaissance high sensitivity radiometric and magnetic survey in north-east Washington. Three 1:250,000 scale NTMS quadrangles (Spokane, Sandpoint, and Okanogan) were surveyed. A total of 14,421 line miles (23,203 kilometers) of data were collected utilizing a Sikorsky S58T helicopter. Traverse lines were flown in an east-west direction at 1.0 and 3.0 mile (1.6 and 4.8 kilometers) spacing, with tie lines flown in a north-south direction at 12 mile (20 kilometer) spacing. The data were digitally recorded at 1.0 second intervals. The NaI terrestrial detectors used in this survey had a total volume of 2,154 cubic inches. The magnetometer employed was a modified ASQ-10 fluxgate system. This report covers only the Okanogan and Sandpoint 1:250,000 scale NTMS quadrangles. Spokane 1:250,000 scale NTMS quadrangle is covered in a separate report. The radiometric data were normalized to 400 feet terrain clearance. The data are presented in the form of computer listings on microfiche and as stacked profile plots. Profile plots are contained in Volume II of this report. A geologic interpretation of the radiometric and magnetic data is included as part of this report

  4. Proceedings of the Conference on Research for the Development of Geothermal Energy Resources

    Science.gov (United States)

    1974-01-01

    The proceedings of a conference on the development of geothermal energy resources are presented. The purpose of the conference was to acquaint potential user groups with the Federal and National Science Foundation geothermal programs and the method by which the users and other interested members can participate in the program. Among the subjects discussed are: (1) resources exploration and assessment, (2) environmental, legal, and institutional research, (3) resource utilization projects, and (4) advanced research and technology.

  5. Mapping cultural resource sites for the Prince William Sound Graphical Resource Database

    International Nuclear Information System (INIS)

    Wooley, C. B.; O'Brien, D. K.; Hillman, S. O.

    1997-01-01

    A software package for mapping digital data 'layers' of environmentally and/or culturally sensitive areas such as seabird colonies, seal haulouts, and sea otter concentrations in Prince William Sound and adjoining areas of southern Alaska has been developed by the Alyeska Pipeline Service Company. The data is to be added to an environmental computer mapping database. More than 1,800 known and reported coastal cultural resource sites have been identified. The database is part of the Prince William Sound Tanker Oil Discharge Prevention and Contingency Plan. The mappable data layers can be used to plan and execute whatever site protection program may be necessary, thus enhancing effective cultural resource protection during an oil spill response. 22 refs., 4 figs

  6. Vaccinium bracteatum Thunb. Leaves' polysaccharide alleviates hepatic gluconeogenesis via the downregulation of miR-137.

    Science.gov (United States)

    Qian, Hai-Feng; Li, Yan; Wang, Li

    2017-11-01

    Vaccinium bracteatum Thunb.(VBT) is a traditional Chinese herb that recorded has an effect of hypoglycemic. We previous discovered a dose-dependent anti-diabetic function of VBT. leaves' polysaccharide (VBTLP), but little is known about its underlying molecular mechanism. Therefore, we hypothesized that VBTLP would decrease hepatic gluconeogenesis to improve glucose metabolism in mice. To test this hypothesis, glucose tolerance test was performed to evaluate the effect of VBTLP on mice hepatic gluconeogenesis. Western blot and RT-PCR were performed to measure both in vivo and in vitro gene regulation under VBTLP treatment. Online bioinformatic analysis was performed to discover a target candidate, miR-137 of LKB1 and AMPK under VBTLP treatment, and the luciferase assay was conducted to validate it. Here we found that VBT. leaves' polysaccharide (VBTLP) decreased hepatic gluconeogenesis via activation of LKB1/AMPK axis in vivo and in vitro. Mechanistic studies reveal that miR-137 regulates hepatic glucose homeostasis by directly targeting AMPK and LKB1. Furthermore, we shown that VBTLP decreased hepatic miR-137 level, which might contribute to activation of LKB1/AMPK and downregulation of gluconeogenesis. Taken together, our study shown that the mechanisms might involve in VBTLP hypoglycemic effect, alleviates hepatic gluconeogenesis via the downregulation of miR-137. Our findings provide guidance in developing novel, safe and effective therapies for T2DM. Copyright © 2017. Published by Elsevier Masson SAS.

  7. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Program State Legislation Tracked by the College Maintenance of Certification Quality Quality Quality Electronic Health Records (EHR) Incentive Program Physician Quality Reporting System Value-Based Payment Modifier Quality and Resource Use ...

  8. U.S. Geological Survey program of offshore resource and geoenvironmental studies, Atlantic-Gulf of Mexico region, from September 1, 1976, to December 31, 1978

    Science.gov (United States)

    Folger, David W.; Needell, Sally W.

    1983-01-01

    Mineral and energy resources of the continental margins of the United States arc important to the Nation's commodity independence and to its balance of payments. These resources are being studied along the continental margins of the Atlantic Ocean and the Gulf of Mexico in keeping with the mission of the U.S. Geological Survey to survey the geologic structures, mineral resources, and products of the national domain.'(Organic Act of 1879). An essential corollary to these resource studies is the study of potential geologic hazards that may be associated with offshore resource exploration and exploitation. In cooperation with the U.S. Bureau of Land Management, the Geological Survey, through its Atlantic-Gulf of Mexico Marine Geology Program, carries out extensive research to evaluate hazards from sediment mobility, shallow gas, and slumping and to acquire information on the distribution and concentration of trace metals and biogenic and petroleum-derived hydrocarbons in sea-floor sediments. All these studies arc providing needed background information, including information on pollutant dispersal, on the nearshore, estuarine, and lacustrine areas that may be near pipeline and nuclear powerplant sites. Users of these data include the Congress, many Federal agencies, the coastal States, private industry, academia, and the concerned public. The results of the regional structural, stratigraphic, and resource studies carried out under the Atlantic-Gulf of Mexico Marine Geology Program have been used by the Geological Survey and the Bureau of Land Management to select areas for future leasing and to aid in the evaluation of tracts nominated for leasing. Resource studies have concentrated mostly on the Atlantic Outer Continental Shelf frontier areas. Geologic detailing of five major basins along the U.S. Atlantic margin, where sediments are as much as 14 km thick, have been revealed by 25,000 km of 24-and 48-channel common-depth-point seismic data, 187,000 km of

  9. Kansas' forest resources, 2005

    Science.gov (United States)

    W. Keith Moser; Gary J. Brand; Melissa Powers

    2007-01-01

    The USDA Forest Service, Northern Research Station, Forest Inventory and Analysis (NRS-FIA) program is changing to a Web-based, dynamically linked reporting system. As part of the process, this year NRS-FIA is producing this abbreviated summary of 2005 data. This resource bulletin reports on area, volume, and biomass using data from 2001 through 2005. Estimates from...

  10. Vermont's Forest Resources, 2006

    Science.gov (United States)

    R.S. Morin; R. De Geus

    2008-01-01

    This publication provides an overview of forest resource attributes for Vermont based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These annual estimates, along with web-posted core tables, will be updated annually. For more information regarding past inventory reports...

  11. Maintenance Resources Evaluation Technique.

    Science.gov (United States)

    1999-03-01

    variable Z; P-6 BIBLIOGRAPHY Argentine Air Force. Reglamento de Conduction Logistica RAC 9 (Logistics Management Regulation). Estado Mayor General de ...other hand, too many resources are expensive to acquire and maintain and difficult to transport . 1-1 Sizing the means needed to accomplish its...functional areas (maintenance, supply/inventory, transportation , etc), methodologies of operations research (simulation, mathematical programming

  12. Connecticut's forest resources, 2010

    Science.gov (United States)

    Brett J. Butler; Cassandra Kurtz; Christopher Martin; W. Keith Moser

    2011-01-01

    This publication provides an overview of forest resource attributes for Connecticut based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of this report...

  13. Connecticut's forest resources, 2009

    Science.gov (United States)

    Brett J. Butler; Christopher Martin

    2011-01-01

    This publication provides an overview of forest resource attributes for Connecticut based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of this report...

  14. Pennsylvania's forest resources, 2012

    Science.gov (United States)

    G.L. McCaskill; W.H. McWilliams; C.J. Barnett

    2013-01-01

    This publication provides an overview of forest resource attributes for Pennsylvania based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These annual estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of...

  15. Pennsylvania's forest resources, 2009

    Science.gov (United States)

    G.L. McCaskill; W.H. McWilliams; B.J. Butler; D.M. Meneguzzo; C.J. Barnett; M.H. Hansen

    2011-01-01

    This publication provides an overview of forest resource attributes for Pennsylvania based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These annual estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of...

  16. Pennsylvania's forest resources, 2011

    Science.gov (United States)

    G.L. McCaskill; W.H. McWilliams; C.J. Barnett

    2012-01-01

    This publication provides an overview of forest resource attributes for Pennsylvania based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These annual estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of...

  17. Pennsylvania's forest resources, 2008

    Science.gov (United States)

    G.L. McCaskill; W.H. McWilliams; B.J. Butler; D.M. Meneguzzo; C.J. Barnett; M.H. Hansen

    2011-01-01

    This publication provides an overview of forest resource attributes for Pennsylvania based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These annual estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of...

  18. Pennsylvania's forest resources, 2010

    Science.gov (United States)

    G.L. McCaskill; W.H. McWilliams; C.J. Barnett

    2011-01-01

    This publication provides an overview of forest resource attributes for Pennsylvania based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These annual estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of...

  19. Pennsylvania's forest resources, 2007

    Science.gov (United States)

    G.L. McCaskill; W.H. McWilliams; B.J. Butler; D.M. Meneguzzo; C.J. Barnett; M.H. Hansen

    2011-01-01

    This publication provides an overview of forest resource attributes for Pennsylvania based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These annual estimates, along with web-posted core tables, will be updated annually. For more information, please refer to page 6 of...

  20. Wisconsin's forest resources, 2010

    Science.gov (United States)

    C.H. Perry

    2011-01-01

    This publication provides an overview of forest resource attributes for Wisconsin based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These estimates, along with web-posted core tables, will be updated annually. For more information please refer to page 4 of this report...

  1. Wisconsin's forest resources, 2006

    Science.gov (United States)

    C.H. Perry; V.A. Everson

    2007-01-01

    Figure 2 was revised by the author in August 2008. This publication provides an overview of forest resource attributes for Wisconsin based on an annual inventory conducted by the Forest Inventory and Analysis program at the Northern Research Station of the U.S. Forest Service from 2002-2006. These estimates, along with associated core tables postedon the Internet, are...

  2. Wisconsin's Forest Resources, 2007

    Science.gov (United States)

    C.H. Perry; V.A. Everson

    2008-01-01

    This publication provides an overview of forest resource attributes for Wisconsin based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program of the U.S. Forest Service, Northern Research Station. These estimates, along with web-posted core tables, are updated annually. For more information please refer to page 4 of this report.

  3. Wisconsin's forest resources, 2009

    Science.gov (United States)

    C.H. Perry

    2011-01-01

    This publication provides an overview of forest resource attributes for Wisconsin based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program at the Northern Research Station of the U.S. Forest Service. These estimates, along with web-posted core tables, will be updated annually. For more information, please refer to page 4 of this report...

  4. Ozone Layer Research and Technical Resources

    Science.gov (United States)

    Access information on research and technical resources related to ozone layer science. This page provides links to research efforts led by organizations such as the National Oceanic and Atmospheric Administration, the United Nations Environment Program, an

  5. A Study on Human Resources Development in Nuclear Field

    International Nuclear Information System (INIS)

    Moon, Keehwan; Lee, M. K.; Kim, S. S.; Nam, J. H.; Won, B. C.; Lee, D. S; Hwang, I. A.; Seo, M. W.

    2011-11-01

    The study encompasses 4 major parts, each results being described here under: Various policy alternatives through supply-demand analysis of domestic nuclear skilled manpower are suggested. Human resources development programs of main educational organizations in domestic and overseas are comprehensively reviewed. Establishment of 'Integrated Management Organization' which can combine and manage domestic educational organizations' educational functions is necessary to efficiently deal with the increased educational demand and the shift of educational paradigm from supply-driven to needs-driven education and to make nuclear energy export sustainable. And road map on human resource development to efficiently accomplish 'Integrated Management Organization's mission is suggested. It is provided that an overall strategies for the reasonable educational program reflecting the good practices with their implications in overseas nuclear education programs

  6. Disallowing Same-program Co-schedules to Improve Efficiency in Quad-core Servers

    OpenAIRE

    de Blanche, Andreas; Lundqvist, Thomas

    2017-01-01

    Programs running on different cores in a multicore server are often forced to share resources like off-chip memory, caches, I/O devices, etc. This resource sharing often leads to degraded performance, a slowdown, for the programs that share the resources. A job scheduler can improve performance by co-scheduling programs that use different resources on the same server. The most common approach to solve this co-scheduling problem has been to make job-schedulers resource aware, finding ways to c...

  7. Laser program annual report, 1979

    International Nuclear Information System (INIS)

    Coleman, L.W.; Strack, J.R.

    1980-03-01

    This volume provides a program overview, presenting highlights of the technical accomplishments of the elements of the program, as well as discussions of program resources and facilities. Also covered are the work of the Solid-State Laser program element, which includes systems operations, Nova, and research and development activities

  8. National conference on integrated resource planning: Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    Until recently, state regulators have focused most of their attention on the development of least-cost or integrated resource planning (IRP) processes for electric utilities. A number of commissions are beginning to scrutinize the planning processes of local gas distribution companies (LDCs) because of the increased control that LDCs have over their purchased gas costs (as well as the associated risks) and because of questions surrounding the role and potential of gas end-use efficiency options. Traditionally, resource planning (LDCs) has concentrated on options for purchasing and storing gas. Integrated resource planning involves the creation of a process in which supply-side and demand-side options are integrated to create a resource mix that reliably satisfies customers` short-term and long-term energy service needs at the lowest cost. As applied to gas utilities, an integrated resource plan seeks to balance cost and reliability, and should not be interpreted simply as the search for lowest commodity costs. The National Association of Regulatory Utility Commissioners` (NARUC) Energy Conservation committee asked Lawrence Berkeley Laboratory (LBL) to survey state PUCs to determine the extent to which they have undertaken least cost planning for gas utilities. The survey included the following topics: status of state PUC least-cost planning regulations and practices for gas utilities; type and scope of natural gas DSM programs in effect, including fuel substitution; economic tests and analysis methods used to evaluate DSM programs; relationship between prudency reviews of gas utility purchasing practices and integrated resource planning; key regulatory issued facing gas utilities during the next five years.

  9. National conference on integrated resource planning: Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    Until recently, state regulators have focused most of their attention on the development of least-cost or integrated resource planning (IRP) processes for electric utilities. A number of commissions are beginning to scrutinize the planning processes of local gas distribution companies (LDCs) because of the increased control that LDCs have over their purchased gas costs (as well as the associated risks) and because of questions surrounding the role and potential of gas end-use efficiency options. Traditionally, resource planning (LDCs) has concentrated on options for purchasing and storing gas. Integrated resource planning involves the creation of a process in which supply-side and demand-side options are integrated to create a resource mix that reliably satisfies customers' short-term and long-term energy service needs at the lowest cost. As applied to gas utilities, an integrated resource plan seeks to balance cost and reliability, and should not be interpreted simply as the search for lowest commodity costs. The National Association of Regulatory Utility Commissioners' (NARUC) Energy Conservation committee asked Lawrence Berkeley Laboratory (LBL) to survey state PUCs to determine the extent to which they have undertaken least cost planning for gas utilities. The survey included the following topics: status of state PUC least-cost planning regulations and practices for gas utilities; type and scope of natural gas DSM programs in effect, including fuel substitution; economic tests and analysis methods used to evaluate DSM programs; relationship between prudency reviews of gas utility purchasing practices and integrated resource planning; key regulatory issued facing gas utilities during the next five years.

  10. U.S. Geological Survey; North Carolina's water resources; a partnership with State, Federal and local agencies

    Science.gov (United States)

    Winner, M.D.

    1993-01-01

    For more than 80 years, the Federal-State Cooperative Program in North Carolina has been an effective partnership that provides timely water information for all levels of government. The cooperative program has raised awareness of State and local water problems and issues and has enhanced transfer and exchange of scientific information. The U.S. Geological Survey (USGS) conducts statewide water-resources investigations in North Carolina that include hydrologic data collection, applied research studies, and other interpretive studies. These programs are funded through cooperative agreements with the North Carolina Departments of Environment, Health, and Natural Resources; Human Resources; and Transportation, as well as more than a dozen city and county governmental agencies. The USGS also conducts special studies and data-collection programs for Federal agencies, including the Department of Defense, the U.S. Soil Conservation Service, the Tennessee Valley Authority, and the U.S. Environmental Protection Agency that contribute to North Carolina's water information data base. Highlights of selected programs are presented to show the scope of USGS activities in North Carolina and their usefulness in addressing water-resource problems. The reviewed programs include the statewide data-collection program, estuarine studies, the National Water-Quality Assessment program, military installation restoration program, and groundwater flow model-development program in the Coastal Plain and Piedmont provinces.

  11. Integrated resource planning-concepts and principles

    Energy Technology Data Exchange (ETDEWEB)

    Atkinson, S.

    1994-12-31

    The concepts and principles of integrated resource planning (IRP) are outlined. The following topics are discussed: utility opportunities and methodologies, application considerations, ambitious energy-efficient programs, the future of IRP, three methods to study resource alternatives, the load adjustment method, simultaneous optimization, static analysis, utility profile data, load forecasts and shapes, load data, conversion, variable costs, external analysis, internal analysis, DSM objectives, supply-side prescreening, DSM screening analysis, DSM evaluation, the IRP process, risk analysis, collaborative planning process, and load shape objectives.

  12. Human resource development program for nuclear safety and security in Tokyo Institute of Technology

    International Nuclear Information System (INIS)

    Han, Chi Young; Sagara, Hiroshi; Nagasaka, Hideo

    2014-01-01

    The Academy for Global Nuclear Safety and Security Agent was established at Tokyo Institute of Technology in 2011, to develop global nuclear human resources in the field of 3S (Safety, Security, and Safeguards) as a Program for Leading Graduate Schools supported by MEXT (Ministry of Education, Culture, Sports, Science and Technology). New courses of nuclear safety and security were developed in addition to the existing nuclear engineering program; 1) Environmental Dynamics of Radioactive Nuclides; Numerical simulation of the environmental dispersion of radioactive materials released from hypothetical nuclear accidents and evaluation of the public exposure are performed, by using a computer-based emergency response system, to have students predict the environmental dispersion of radionuclides and radiological consequence by nuclear accidents. 2) Measurement of Environmental Radiation; Students acquire hands-on experiences measuring environmental radiation contamination caused by the nuclear accident in Fukushima with multiple types of radiation detectors. Environmental samples are collected and analyzed for isotope identification and its spatial distribution. 3) Simulation of Severe Nuclear Accidents; The evaluation results of Fukushima accident progression are discussed as well as typical sever accidents that threaten the integrity of reactor vessel. Students simulate BWR (Boiling Water Cooled Reactor) transients, design basis accidents, and severe accidents by using simulators. 4) Nuclear Security Training; Design of physical protection systems, its fundamental physics, and regulatory frameworks are covered and students gain the practical experiences by use of intrusion detection systems at JAEA (Japan Atomic Energy Agency), and by numerical simulation of hydro-dynamics of structure material and nuclear material criticality at the university. (author)

  13. GPSR: A Resource for Genomics Proteomics and Systems Biology

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. GPSR: A Resource for Genomics Proteomics and Systems Biology. Small programs as building unit. Why PERL? Why not BioPerl? Why not PERL modules? Advantage of independent programs. Language independent; Can be run independently.

  14. Screening, management, and treatment of intimate partner violence among women in low-resource settings.

    Science.gov (United States)

    Schwab-Reese, Laura M; Renner, Lynette M

    2018-01-01

    The prevention of intimate partner violence continues to be a high priority for health practitioners and researchers around the world. Screening practices and intervention efforts utilized within high- and/or middle-income areas may not translate effectively to low-resource areas due to differences in financial, social, and physical context. However, little is known about the evidence-base of intervention efforts in such areas. Using the Arksey and O'Malley framework for scoping reviews, the purpose of this review was to synthesize what is known about intimate partner violence screening, management, and treatment in low-resource areas. A total of 31 programs reported across 34 articles were included in this scoping review. The programs incorporated a range of intervention activities, including group-based education and skill-development combined with microfinance to screening and referral to community resources. Slightly less than half of the studies (n = 14) were randomized controlled trials or clustered randomized controlled trials. Many barriers were common across the programs, including limited financial support, lack of community support, and lack of coordination across programs. Despite considerable barriers related to the limited available resources, the literature base had many strengths, such as strong evaluation methodologies, inclusion of a theoretical or conceptual framework to guide the intervention, and community engagement before and during the intervention implementation. However, insufficient statistical power and barriers related to cultural differences or inadequate cultural sensitivity were also common. With a variety of barriers to program implementation noted within the articles, it is important for researchers and practitioners to consider the geographic, social, cultural, and economic contexts when implementing intimate partner violence programs in low-resource areas. Given the significant differences in context across low-resource areas

  15. Training for cervical cancer prevention programs in low-resource settings: focus on visual inspection with acetic acid and cryotherapy.

    Science.gov (United States)

    Blumenthal, P D; Lauterbach, M; Sellors, J W; Sankaranarayanan, R

    2005-05-01

    The modern approach to cervical cancer prevention, characterized by use of cytology and multiple visits for diagnosis and treatment, has frequently proven challenging and unworkable in low-resource settings. Because of this, the Alliance for Cervical Cancer Prevention (ACCP) has made it a priority to investigate and assess alternative approaches, particularly the use of visual screening methods, such as visual inspection with acetic acid (VIA) and visual inspection with Lugol's iodine (VILI), for precancer and cancer detection and the use of cryotherapy as a precancer treatment method. As a result of ACCP experience in providing training to nurses and doctors in these techniques, it is now widely agreed that training should be competency based, combining both didactic and hands-on approaches, and should be done in a clinical setting that resembles the service-delivery conditions at the program site. This article reviews ACCP experiences and perceptions about the essentials of training in visual inspection and cryotherapy and presents some lessons learned with regard to training in these techniques in low-resource settings.

  16. Data Acquisition and Linguistic Resources

    Science.gov (United States)

    Strassel, Stephanie; Christianson, Caitlin; McCary, John; Staderman, William; Olive, Joseph

    All human language technology demands substantial quantities of data for system training and development, plus stable benchmark data to measure ongoing progress. While creation of high quality linguistic resources is both costly and time consuming, such data has the potential to profoundly impact not just a single evaluation program but language technology research in general. GALE's challenging performance targets demand linguistic data on a scale and complexity never before encountered. Resources cover multiple languages (Arabic, Chinese, and English) and multiple genres -- both structured (newswire and broadcast news) and unstructured (web text, including blogs and newsgroups, and broadcast conversation). These resources include significant volumes of monolingual text and speech, parallel text, and transcribed audio combined with multiple layers of linguistic annotation, ranging from word aligned parallel text and Treebanks to rich semantic annotation.

  17. Air quality analysis and related risk assessment for the Bonneville Power Administration's Resource Program

    International Nuclear Information System (INIS)

    Glantz, C.S.; Burk, K.W.; Driver, C.J.; Liljegren, J.C.; Neitzel, D.A.; Schwartz, M.N.; Dana, M.T.; Laws, G.L.; Mahoney, L.A.; Rhoads, K.

    1992-04-01

    The Bonneville Power Administration (BPA) is considering 12 different alternatives for acquiring energy resources over the next 20 years. Each of the alternatives utilizes a full range of energy resources (e.g., coal, cogeneration, conservation, and nuclear); however, individual alternatives place greater emphases on different types of power-producing resources and employ different timetables for implementing these resources. The environmental impacts that would result from the implementation of each alternative and the economic valuations of these impacts, will be an important consideration in the alternative selection process. In this report we discuss the methods used to estimate environmental impacts from the resource alternatives. We focus on pollutant emissions rates, ground-level air concentrations of basic criteria pollutants, the acidity of rain, particulate deposition, ozone concentrations, visibility attenuation, global warming, human health effects, agricultural and forest impacts, and wildlife impacts. For this study, pollutant emission rates are computed by processing BPA data on power production and associated pollutant emissions. The assessment of human health effects from ozone indicated little variation between the resource alternatives. Impacts on plants, crops, and wildlife populations from power plant emissions are projected to be minimal for all resource alternatives

  18. Laser program annual report, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, L.W.; Strack, J.R. (eds.)

    1980-03-01

    This volume provides a program overview, presenting highlights of the technical accomplishments of the elements of the program, as well as discussions of program resources and facilities. Also covered are the work of the Solid-State Laser program element, which includes systems operations, Nova, and research and development activities. (MOW)

  19. New Mexico low-temperature geothermal resources and economic development programs

    International Nuclear Information System (INIS)

    Whittier, J.; Schoenmackers, R.

    1990-01-01

    This paper reports on New Mexico's low-temperature geothermal resources which have been utilized to promote economic development initiatives within the state. Public funds have been leveraged to foster exploration activities which have led to the establishment of several direct-use projects at various sites within New Mexico. State policies have focused on attracting one business sector, the commercial greenhouse industry, to expand and/or relocate in New Mexico. Geothermal-related promotional activities have begun to show success in achieving economic growth. New Mexico now has almost half of the geothermally-heated greenhouse space in the nation. It is anticipated that the greenhouse sector will continue to grow within the state. Future economic development activities, also relying upon the geothermal resource base, will include vegetable dehydration and aquaculture with a focus on the microalgae sector

  20. Noise-Induced Loss of Hair Cells and Cochlear Synaptopathy Are Mediated by the Activation of AMPK

    Science.gov (United States)

    Hill, Kayla; Yuan, Hu; Wang, Xianren

    2016-01-01

    Noise-induced hearing loss (NIHL) is a major unresolved public health problem. Here, we investigate pathomechanisms of sensory hair cell death and suggest a novel target for protective intervention. Cellular survival depends upon maintenance of energy homeostasis, largely by AMP-activated protein kinase (AMPK). In response to a noise exposure in CBA/J mice, the levels of phosphorylated AMPKα increased in hair cells in a noise intensity-dependent manner. Inhibition of AMPK via siRNA or the pharmacological inhibitor compound C attenuated noise-induced loss of outer hair cells (OHCs) and synaptic ribbons, and preserved auditory function. Additionally, noise exposure increased the activity of the upstream AMPK kinase liver kinase B1 (LKB1) in cochlear tissues. The inhibition of LKB1 by siRNA attenuated the noise-increased phosphorylation of AMPKα in OHCs, reduced the loss of inner hair cell synaptic ribbons and OHCs, and protected against NIHL. These results indicate that noise exposure induces hair cell death and synaptopathy by activating AMPK via LKB1-mediated pathways. Targeting these pathways may provide a novel route to prevent NIHL. SIGNIFICANCE STATEMENT Our results demonstrate for the first time that the activation of AMP-activated protein kinase (AMPK) α in sensory hair cells is noise intensity dependent and contributes to noise-induced hearing loss by mediating the loss of inner hair cell synaptic ribbons and outer hair cells. Noise induces the phosphorylation of AMPKα1 by liver kinase B1 (LKB1), triggered by changes in intracellular ATP levels. The inhibition of AMPK activation by silencing AMPK or LKB1, or with the pharmacological inhibitor compound C, reduced outer hair cell and synaptic ribbon loss as well as noise-induced hearing loss. This study provides new insights into mechanisms of noise-induced hearing loss and suggests novel interventions for the prevention of the loss of sensory hair cells and cochlear synaptopathy. PMID:27413159

  1. Resveratrol-Induced AMP-Activated Protein Kinase Activation Is Cell-Type Dependent: Lessons from Basic Research for Clinical Application.

    Science.gov (United States)

    Lan, Fan; Weikel, Karen A; Cacicedo, Jose M; Ido, Yasuo

    2017-07-14

    Despite the promising effects of resveratrol, its efficacy in the clinic remains controversial. We were the first group to report that the SIRT1 activator resveratrol activates AMP-activated protein kinase (AMPK) (Diabetes 2005; 54: A383), and we think that the variability of this cascade may be responsible for the inconsistency of resveratrol's effects. Our current studies suggest that the effect of SIRT1 activators such as resveratrol may not be solely through activation of SIRT1, but also through an integrated effect of SIRT1-liver kinase B1 (LKB1)-AMPK. In this context, resveratrol activates SIRT1 (1) by directly binding to SIRT1; and (2) by increasing NAD⁺ levels by upregulating the salvage pathway through Nampt activation, an effect mediated by AMPK. The first mechanism promotes deacetylation of a limited number of SIRT1 substrate proteins (e.g., PGC-1). The second mechanism (which may be more important than the first) activates other sirtuins in addition to SIRT1, which affects a broad spectrum of substrates. Despite these findings, detailed mechanisms of how resveratrol activates AMPK have not been reported. Here, we show that (1) resveratrol-induced activation of AMPK requires the presence of functional LKB1; (2) Resveratrol increases LKB1 activity, which involves translocation and phosphorylation at T336 and S428; (3) Activation of LKB1 causes proteasomal degradation of LKB1; (4) At high concentrations (50-100 µM), resveratrol also activates AMPK through increasing AMP levels; and (5) The above-mentioned activation mechanisms vary among cell types, and in some cell types, resveratrol fails to activate AMPK. These results suggest that resveratrol-induced activation of AMPK is not a ubiquitous phenomenon. In addition, AMPK-mediated increases in NAD⁺ in the second mechanism require several ATPs, which may not be available in many pathological conditions. These phenomena may explain why resveratrol is not always consistently beneficial in a clinical

  2. Noise-Induced Loss of Hair Cells and Cochlear Synaptopathy Are Mediated by the Activation of AMPK.

    Science.gov (United States)

    Hill, Kayla; Yuan, Hu; Wang, Xianren; Sha, Su-Hua

    2016-07-13

    Noise-induced hearing loss (NIHL) is a major unresolved public health problem. Here, we investigate pathomechanisms of sensory hair cell death and suggest a novel target for protective intervention. Cellular survival depends upon maintenance of energy homeostasis, largely by AMP-activated protein kinase (AMPK). In response to a noise exposure in CBA/J mice, the levels of phosphorylated AMPKα increased in hair cells in a noise intensity-dependent manner. Inhibition of AMPK via siRNA or the pharmacological inhibitor compound C attenuated noise-induced loss of outer hair cells (OHCs) and synaptic ribbons, and preserved auditory function. Additionally, noise exposure increased the activity of the upstream AMPK kinase liver kinase B1 (LKB1) in cochlear tissues. The inhibition of LKB1 by siRNA attenuated the noise-increased phosphorylation of AMPKα in OHCs, reduced the loss of inner hair cell synaptic ribbons and OHCs, and protected against NIHL. These results indicate that noise exposure induces hair cell death and synaptopathy by activating AMPK via LKB1-mediated pathways. Targeting these pathways may provide a novel route to prevent NIHL. Our results demonstrate for the first time that the activation of AMP-activated protein kinase (AMPK) α in sensory hair cells is noise intensity dependent and contributes to noise-induced hearing loss by mediating the loss of inner hair cell synaptic ribbons and outer hair cells. Noise induces the phosphorylation of AMPKα1 by liver kinase B1 (LKB1), triggered by changes in intracellular ATP levels. The inhibition of AMPK activation by silencing AMPK or LKB1, or with the pharmacological inhibitor compound C, reduced outer hair cell and synaptic ribbon loss as well as noise-induced hearing loss. This study provides new insights into mechanisms of noise-induced hearing loss and suggests novel interventions for the prevention of the loss of sensory hair cells and cochlear synaptopathy. Copyright © 2016 the authors 0270-6474/16/367497-14$15.00/0.

  3. The Benefits of Including Clinical Factors in Rectal Normal Tissue Complication Probability Modeling After Radiotherapy for Prostate Cancer

    International Nuclear Information System (INIS)

    Defraene, Gilles; Van den Bergh, Laura; Al-Mamgani, Abrahim; Haustermans, Karin; Heemsbergen, Wilma; Van den Heuvel, Frank; Lebesque, Joos V.

    2012-01-01

    Purpose: To study the impact of clinical predisposing factors on rectal normal tissue complication probability modeling using the updated results of the Dutch prostate dose-escalation trial. Methods and Materials: Toxicity data of 512 patients (conformally treated to 68 Gy [n = 284] and 78 Gy [n = 228]) with complete follow-up at 3 years after radiotherapy were studied. Scored end points were rectal bleeding, high stool frequency, and fecal incontinence. Two traditional dose-based models (Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) and a logistic model were fitted using a maximum likelihood approach. Furthermore, these model fits were improved by including the most significant clinical factors. The area under the receiver operating characteristic curve (AUC) was used to compare the discriminating ability of all fits. Results: Including clinical factors significantly increased the predictive power of the models for all end points. In the optimal LKB, RS, and logistic models for rectal bleeding and fecal incontinence, the first significant (p = 0.011–0.013) clinical factor was “previous abdominal surgery.” As second significant (p = 0.012–0.016) factor, “cardiac history” was included in all three rectal bleeding fits, whereas including “diabetes” was significant (p = 0.039–0.048) in fecal incontinence modeling but only in the LKB and logistic models. High stool frequency fits only benefitted significantly (p = 0.003–0.006) from the inclusion of the baseline toxicity score. For all models rectal bleeding fits had the highest AUC (0.77) where it was 0.63 and 0.68 for high stool frequency and fecal incontinence, respectively. LKB and logistic model fits resulted in similar values for the volume parameter. The steepness parameter was somewhat higher in the logistic model, also resulting in a slightly lower D 50 . Anal wall DVHs were used for fecal incontinence, whereas anorectal wall dose best described the other two endpoints. Conclusions

  4. The Benefits of Including Clinical Factors in Rectal Normal Tissue Complication Probability Modeling After Radiotherapy for Prostate Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Defraene, Gilles, E-mail: gilles.defraene@uzleuven.be [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Van den Bergh, Laura [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Al-Mamgani, Abrahim [Department of Radiation Oncology, Erasmus Medical Center - Daniel den Hoed Cancer Center, Rotterdam (Netherlands); Haustermans, Karin [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Heemsbergen, Wilma [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands); Van den Heuvel, Frank [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Lebesque, Joos V. [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands)

    2012-03-01

    Purpose: To study the impact of clinical predisposing factors on rectal normal tissue complication probability modeling using the updated results of the Dutch prostate dose-escalation trial. Methods and Materials: Toxicity data of 512 patients (conformally treated to 68 Gy [n = 284] and 78 Gy [n = 228]) with complete follow-up at 3 years after radiotherapy were studied. Scored end points were rectal bleeding, high stool frequency, and fecal incontinence. Two traditional dose-based models (Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) and a logistic model were fitted using a maximum likelihood approach. Furthermore, these model fits were improved by including the most significant clinical factors. The area under the receiver operating characteristic curve (AUC) was used to compare the discriminating ability of all fits. Results: Including clinical factors significantly increased the predictive power of the models for all end points. In the optimal LKB, RS, and logistic models for rectal bleeding and fecal incontinence, the first significant (p = 0.011-0.013) clinical factor was 'previous abdominal surgery.' As second significant (p = 0.012-0.016) factor, 'cardiac history' was included in all three rectal bleeding fits, whereas including 'diabetes' was significant (p = 0.039-0.048) in fecal incontinence modeling but only in the LKB and logistic models. High stool frequency fits only benefitted significantly (p = 0.003-0.006) from the inclusion of the baseline toxicity score. For all models rectal bleeding fits had the highest AUC (0.77) where it was 0.63 and 0.68 for high stool frequency and fecal incontinence, respectively. LKB and logistic model fits resulted in similar values for the volume parameter. The steepness parameter was somewhat higher in the logistic model, also resulting in a slightly lower D{sub 50}. Anal wall DVHs were used for fecal incontinence, whereas anorectal wall dose best described the other two endpoints

  5. Geothermal low-temperature reservoir assessment program: A new DOE geothermal initiative

    International Nuclear Information System (INIS)

    Wright, P.M.; Lienau, P.J.; Mink, L.L.

    1992-01-01

    In Fiscal Year 1991, Congress appropriated money for the Department of Energy to begin a new program in the evaluation and use of low- and moderate-temperature geothermal resources. The objective of this program is to promote accelerated development of these resources to offset fossil-fuel use and help improve the environment. The program will consist of several components, including: (1) compilation of all available information on resource location and characteristics, with emphasis on resources located within 5 miles of population centers; (2) development and testing of techniques to discover and evaluate low- and moderate-temperature geothermal resources; (3) technical assistance to potential developers of low- and moderate-temperature geothermal resources; and (4) evaluation of the use of geothermal heat pumps in domestic and commercial applications. Program participants will include the Geo-Heat Center at the Oregon Institute of Technology, the University of Utah Research Institute, the Idaho Water Resources Research Institute and agencies of state governments in most of the western states

  6. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Program Trauma Education Achieving Zero Preventable Deaths Conference Publications and Posters National Trauma System Injury Prevention and ... Division of Education ACS Education and Training Courses Publications Resources Education Program Videos Contact Us Clinical Congress ...

  7. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Associate Fellows Residents Medical Students Affiliate Members ACS Insurance Programs ACS Discount Programs FACS Resources Career Connection ... and Awards Overview Scholarships, Fellowships, and Awards Overview Health Policy Scholarships Scholarships for International Surgeons Research Scholarships ...

  8. Subtypes in clinical burnout patients enrolled in an employee rehabilitation program: differences in burnout profiles, depression, and recovery/resources-stress balance.

    Science.gov (United States)

    Bauernhofer, Kathrin; Bassa, Daniela; Canazei, Markus; Jiménez, Paulino; Paechter, Manuela; Papousek, Ilona; Fink, Andreas; Weiss, Elisabeth M

    2018-01-17

    Burnout is generally perceived a unified disorder with homogeneous symptomatology across people (exhaustion, cynicism, and reduced professional efficacy). However, increasing evidence points to intra-individual patterns of burnout symptoms in non-clinical samples such as students, athletes, healthy, and burned-out employees. Different burnout subtypes might therefore exist. Yet, burnout subtypes based on burnout profiles have hardly been explored in clinical patients, and the samples investigated in previous studies were rather heterogeneous including patients with various physical, psychological, and social limitations, symptoms, and disabilities. Therefore, the aim of this study is to explore burnout subtypes based on burnout profiles in clinically diagnosed burnout patients enrolled in an employee rehabilitation program, and to investigate whether the subtypes differ in depression, recovery/resources-stress balance, and sociodemographic characteristics. One hundred three patients (66 women, 37 men) with a clinical burnout diagnosis, who were enrolled in a 5 week employee rehabilitation program in two specialized psychosomatic clinics in Austria, completed a series of questionnaires including the Maslach Burnout Inventory - General Survey (MBI-GS), the Beck Depression Inventory, and the Recovery-Stress-Questionnaire for Work. Cluster analyses with the three MBI-GS subscales as clustering variables were used to identify the burnout subtypes. Subsequent multivariate/univariate analysis of variance and Pearson chi-square tests were performed to investigate differences in depression, recovery/resources-stress balance, and sociodemographic characteristics. Three different burnout subtypes were discovered: the exhausted subtype, the exhausted/cynical subtype, and the burned-out subtype. The burned-out subtype and the exhausted/cynical subtype showed both more severe depression symptoms and a worse recovery/resources-stress balance than the exhausted subtype

  9. Wind Energy Resource Atlas of Mongolia

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, D; Schwartz, M; Scott, G.; Haymes, S.; Heimiller, D.; George, R.

    2001-08-27

    The United States Department of Energy (DOE) and the United States Agency for International Development (USAID) sponsored a project to help accelerate the large-scale use of wind energy technologies in Mongolia through the development of a wind energy resource atlas of Mongolia. DOE's National Renewable Energy Laboratory (NREL) administered and conducted this project in collaboration with USAID and Mongolia. The Mongolian organizations participating in this project were the Scientific, Production, and Trade Corporation for Renewable Energy (REC) and the Institute of Meteorology and Hydrology (IMH). The primary goals of the project were to develop detailed wind resource maps for all regions of Mongolia for a comprehensive wind resource atlas, and to establish a wind-monitoring program to identify prospective sites for wind energy projects and help validate some of the wind resource estimates.

  10. RESOURCE ALLOCATION IN A MAIZE BREEDING PROGRAM FOR NATIVE RESISTANCE TO WESTERN CORN ROOTWORM

    Directory of Open Access Journals (Sweden)

    Ivan Brkić

    2012-06-01

    Full Text Available The objective of this study was to determine the optimum allocation of the number of plants sampled per plot and number of locations and years required for screening maize genotypes for reduced root damage caused by western corn rootworm (WCR larvae, major pest of maize in Croatia, Europe and in the USA. Field trials were conducted on two locations Eastern Croatia, a major maize production area with natural WCR occurrence under continuous maize growing conditions. The trials were set as an incomplete lattice block design in two replications in 2007, 2008 and 2009 including 128 genotypes from various maize gene-pools. Our results suggest that the effect of year and respective interactions including year were the most important factors in maize breeding programs for native resistance to WCR. Thus, screening germplasm for WCR resistance should be made in a multi-year experiment, but not necessarily as a multi-location experiment. Resource optimization should be done by reducing number of roots per plot to minimum 4 sampled plants due to small within-plot environmental variance.

  11. Achieving excellence with limited resources

    International Nuclear Information System (INIS)

    Anson, L.W.; Spinney, R.W.

    1985-01-01

    The achievement of excellence in safety of nuclear power plant operation is dependent in part upon establishment of a performance-based training program. Developing such a program can be a laborious, time-consuming, and very expensive effort. Conducting job and task analyses, designing course outlines from learning objectives, developing training materials, evaluating program effectiveness and managing the training process and program through the out-years will exhaust any utility's training budget and staff. Because the achievement of excellence implies that training become in part performance-based, the question arises of how best to attain quality training yet still maintain a reasonable budget and staff workload. The answer lies not just in contracting the support necessary but making use of all available resources - training staff, contractor personnel in INPO

  12. Institutional shared resources and translational cancer research

    Directory of Open Access Journals (Sweden)

    De Paoli Paolo

    2009-06-01

    Full Text Available Abstract The development and maintenance of adequate shared infrastructures is considered a major goal for academic centers promoting translational research programs. Among infrastructures favoring translational research, centralized facilities characterized by shared, multidisciplinary use of expensive laboratory instrumentation, or by complex computer hardware and software and/or by high professional skills are necessary to maintain or improve institutional scientific competitiveness. The success or failure of a shared resource program also depends on the choice of appropriate institutional policies and requires an effective institutional governance regarding decisions on staffing, existence and composition of advisory committees, policies and of defined mechanisms of reporting, budgeting and financial support of each resource. Shared Resources represent a widely diffused model to sustain cancer research; in fact, web sites from an impressive number of research Institutes and Universities in the U.S. contain pages dedicated to the SR that have been established in each Center, making a complete view of the situation impossible. However, a nation-wide overview of how Cancer Centers develop SR programs is available on the web site for NCI-designated Cancer Centers in the U.S., while in Europe, information is available for individual Cancer centers. This article will briefly summarize the institutional policies, the organizational needs, the characteristics, scientific aims, and future developments of SRs necessary to develop effective translational research programs in oncology. In fact, the physical build-up of SRs per se is not sufficient for the successful translation of biomedical research. Appropriate policies to improve the academic culture in collaboration, the availability of educational programs for translational investigators, the existence of administrative facilitations for translational research and an efficient organization

  13. Institutional shared resources and translational cancer research.

    Science.gov (United States)

    De Paoli, Paolo

    2009-06-29

    The development and maintenance of adequate shared infrastructures is considered a major goal for academic centers promoting translational research programs. Among infrastructures favoring translational research, centralized facilities characterized by shared, multidisciplinary use of expensive laboratory instrumentation, or by complex computer hardware and software and/or by high professional skills are necessary to maintain or improve institutional scientific competitiveness. The success or failure of a shared resource program also depends on the choice of appropriate institutional policies and requires an effective institutional governance regarding decisions on staffing, existence and composition of advisory committees, policies and of defined mechanisms of reporting, budgeting and financial support of each resource. Shared Resources represent a widely diffused model to sustain cancer research; in fact, web sites from an impressive number of research Institutes and Universities in the U.S. contain pages dedicated to the SR that have been established in each Center, making a complete view of the situation impossible. However, a nation-wide overview of how Cancer Centers develop SR programs is available on the web site for NCI-designated Cancer Centers in the U.S., while in Europe, information is available for individual Cancer centers. This article will briefly summarize the institutional policies, the organizational needs, the characteristics, scientific aims, and future developments of SRs necessary to develop effective translational research programs in oncology.In fact, the physical build-up of SRs per se is not sufficient for the successful translation of biomedical research. Appropriate policies to improve the academic culture in collaboration, the availability of educational programs for translational investigators, the existence of administrative facilitations for translational research and an efficient organization supporting clinical trial recruitment

  14. Activities of nuclear human resource development in nuclear industry

    International Nuclear Information System (INIS)

    Tsujikura, Yonezo

    2010-01-01

    Since 2007, the JAIF (Japan Atomic Industrial Forum) had established the nuclear energy human resource development council to make analysis of the issue on nuclear human resource development. The author mainly contributed to develop its road map as a chairman of working group. Questionnaire survey to relevant parties on issues of nuclear human resource development had been conducted and the council identified the six relevant issues and ten recommendations. Both aspects for career design and skill-up program are necessary to develop nuclear human resource at each developing step and four respective central coordinating hubs should be linked to each sector participating in human resource development. (T. Tanaka)

  15. 24 CFR 984.202 - Program Coordinating Committee (PCC).

    Science.gov (United States)

    2010-04-01

    ... private education or training institutions, child care providers, nonprofit service providers, private business, and any other public and private service providers with resources to assist the FSS program. (c... private resources for the operation of the FSS program within the PHA's jurisdiction, including assistance...

  16. Nationwide Natural Resource Inventory of the Philippines Using Lidar: Strategies, Progress, and Challenges

    Science.gov (United States)

    Blanco, A. C.; Tamondong, A.; Perez, A. M.; Ang, M. R. C.; Paringit, E.; Alberto, R.; Alibuyog, N.; Aquino, D.; Ballado, A.; Garcia, P.; Japitana, M.; Ignacio, M. T.; Macandog, D.; Novero, A.; Otadoy, R. E.; Regis, E.; Rodriguez, M.; Silapan, J.; Villar, R.

    2016-06-01

    The Philippines has embarked on a detailed nationwide natural resource inventory using LiDAR through the Phil-LiDAR 2 Program. This 3-year program has developed and has been implementing mapping methodologies and protocols to produce high-resolution maps of agricultural, forest, coastal marine, hydrological features, and renewable energy resources. The Program has adopted strategies on system and process development, capacity building and enhancement, and expanding the network of collaborations. These strategies include training programs (on point cloud and image processing, GIS, and field surveys), workshops, forums, and colloquiums (program-wide, cluster-based, and project-based), and collaboration with partner national government agencies and other organizations. In place is a cycle of training, implementation, and feedback in order to continually improve the system and processes. To date, the Program has achieved progress in the development of workflows and in rolling out products such as resource maps and GIS data layers, which are indispensable in planning and decision-making. Challenges remains in speeding up output production (including quality checks) and in ensuring sustainability considering the short duration of the program. Enhancements in the workflows and protocols have been incorporated to address data quality and data availability issues. More trainings have been conducted for project staff hired to address human resource gaps. Collaborative arrangements with more partners are being established. To attain sustainability, the Program is developing and instituting a system of training, data updating and sharing, information utilization, and feedback. This requires collaboration and cooperation of the government agencies, LGUs, universities, other organizations, and the communities.

  17. Raising a Red Flag on Dating Violence: Evaluation of a Low-Resource, College-Based Bystander Behavior Intervention Program.

    Science.gov (United States)

    Borsky, Amanda E; McDonnell, Karen; Turner, Monique Mitchell; Rimal, Rajiv

    2016-03-09

    Encouraging bystanders to intervene safely and effectively in situations that could escalate to violence-known as bystander behavior programs-is a growing yet largely untested strategy to prevent dating violence. Using a quasi-experimental design, we evaluate a low-resource, low-intensity intervention aimed at preventing dating violence among college students. The integrated behavioral model (IBM) was used to guide the evaluation. We also assess which IBM variables were most strongly associated with bystander behaviors. Participants were drawn from two Virginia colleges that predominantly train females in the health profession sciences. The intervention group (n = 329) participated in a university-wide bystander behavior intervention consisting of a 30-min presentation on dating violence at new-student orientation and a week-long "red flag" social marketing campaign on campus to raise awareness of dating violence. Controlling for changes at the comparison university, results showed an increase in bystander behaviors, such as encouraging a friend who may be in an abusive relationship to get help, after the intervention and adjusting for potential confounders (increase of 1.41 bystander behaviors, p = .04). However, no significant changes were found for bystander intentions, self-efficacy, social norms, or attitudes related to dating violence from pre- to post-intervention. Self-efficacy had a direct relationship with bystander behaviors. Results suggest that low-resource interventions have a modest effect on increasing bystander behaviors. However, higher resource interventions likely are needed for a larger impact, especially among students who already demonstrate strong baseline intentions to intervene and prevent dating violence. © The Author(s) 2016.

  18. Resource development and the Mackenzie Valley Resource Management Act

    International Nuclear Information System (INIS)

    Donihee, J.

    1999-01-01

    Changes to the resource management regime of the Northwest Territories based on land claim agreements with native peoples which result from the Mackenzie Valley Resource Management Act are the result of commitments made by Canada during the negotiation of these land claims. This statute effects important changes to the legislative framework for environmental impact assessment and land and water management. It also establishes land use planning processes for the Gwich'in and Sahtu settlement areas and will result in an environmental and cumulative effects monitoring program for the Mackenzie Valley. The Act also establishes new institutions of public government responsible for environmental impact assessment, land and water management, and land use planning. These boards will play an internal and continuing role in resource development and management in the Mackenzie Valley. A brief overview is included of some features of the new legislative scheme, specifically focussing on environmental impact assessment and water management. An understanding of the new regime will be important for oil and gas companies that are looking north with renewed interest as a result of improved oil and gas prices and also for mining companies given the continuing interest in diamond exploration and development in the Northwest Territories. 29 refs

  19. Human resource development for the new nuclear power plant unit in Armenia

    International Nuclear Information System (INIS)

    Gevorgyan, A.; Galstyan, A.; Donovan, M.

    2008-01-01

    This paper presents a discussion of a study to define the programs for development of the human resource infrastructure needed for a new nuclear power plant unit in the Republic of Armenia. While Armenia has a workforce experienced in operation and regulation of a nuclear power plant (NPP), a significant portion of the current Armenia Nuclear Power Plant (ANPP) workforce is approaching retirement age and will not be available for the new plant. The Government of Armenia is performing a human resource infrastructure study in cooperation with the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO), sponsored by the JAEA. The study of Human Resource Development for Armenia uses the INPRO methodology for assessment of human resources. The results of this study will provide the basis for decisions on human resource development programs for nuclear power in Armenia and provide a model for countries with the limited resources that are working to develop nuclear energy in the future. (authors)

  20. Examining Extension's Capacity in Community Resource and Economic Development: Viewpoints of Extension Administrators on the Role of Community Resource and Economic Development in the Extension Portfolio

    Science.gov (United States)

    Urbanowitz, Seth C.; Wilcox, Michael D., Jr.

    2013-01-01

    The survey-based research reported here offers insights on community, resource, and economic development (CRED) Extension programming at the national and regional level. The results present a national picture of CRED programming, research, and potential future programming opportunities that Extension could capitalize on. The research shows that…