WorldWideScience

Sample records for program included irradiated

  1. ATF Neutron Irradiation Program Irradiation Vehicle Design Concepts

    Energy Technology Data Exchange (ETDEWEB)

    Geringer, J. W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Katoh, Yutai [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Howard, Richard H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Cetiner, N. O. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Petrie, Christian M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Smith, Kurt R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; McDuffee, J. M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division

    2016-03-01

    The Japan Atomic Energy Agency (JAEA) under the Civil Nuclear Energy Working Group (CNWG) is engaged in a cooperative research effort with the U.S. Department of Energy (DOE) to explore issues related to nuclear energy, including research on accident-tolerant fuels and materials for use in light water reactors. This work develops a draft technical plan for a neutron irradiation program on the candidate accident-tolerant fuel cladding materials and elements using the High Flux Isotope Reactor (HFIR). The research program requires the design of a detailed experiment, development of test vehicles, irradiation of test specimens, possible post irradiation examination and characterization of irradiated materials and the shipment of irradiated materials to Japan. This report discusses the conceptual design, the development and irradiation of the test vehicles.

  2. ATF Neutron Irradiation Program Technical Plan

    Energy Technology Data Exchange (ETDEWEB)

    Geringer, J. W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Katoh, Yutai [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division

    2016-03-01

    The Japan Atomic Energy Agency (JAEA) under the Civil Nuclear Energy Working Group (CNWG) is engaged in a cooperative research effort with the U.S. Department of Energy (DOE) to explore issues related to nuclear energy, including research on accident-tolerant fuels and materials for use in light water reactors. This work develops a draft technical plan for a neutron irradiation program on the candidate accident-tolerant fuel cladding materials and elements using the High Flux Isotope Reactor (HFIR). The research program requires the design of a detailed experiment, development of test vehicles, irradiation of test specimens, possible post-irradiation examination and characterization of irradiated materials and the shipment of irradiated materials to JAEA in Japan. This report discusses the technical plan of the experimental study.

  3. Heavy-Section Steel Irradiation Program

    Energy Technology Data Exchange (ETDEWEB)

    Rosseel, T.M.

    2000-04-01

    Maintaining the integrity of the reactor pressure vessel (RPV) in a light-water-cooled nuclear power plant is crucial in preventing and controlling severe accidents that have the potential for major contamination release. Because the RPV is the only key safety-related component of the plant for which a redundant backup system does not exist, it is imperative to fully understand the degree of irradiation-induced degradation of the RPV's fracture resistance that occurs during service. For this reason, the Heavy-Section Steel Irradiation (HSSI) Program has been established.

  4. Education Program on Fossil Resources Including Coal

    Science.gov (United States)

    Usami, Masahiro

    Fossil fuels including coal play a key role as crucial energies in contributing to economic development in Asia. On the other hand, its limited quantity and the environmental problems causing from its usage have become a serious global issue and a countermeasure to solve such problems is very much demanded. Along with the pursuit of sustainable development, environmentally-friendly use of highly efficient fossil resources should be therefore, accompanied. Kyushu-university‧s sophisticated research through long years of accumulated experience on the fossil resources and environmental sectors together with the advanced large-scale commercial and empirical equipments will enable us to foster cooperative research and provide internship program for the future researchers. Then, this program is executed as a consignment business from the Ministry of Economy, Trade and Industry from 2007 fiscal year to 2009 fiscal year. The lecture that uses the textbooks developed by this program is scheduled to be started a course in fiscal year 2010.

  5. Short-term antioxidative responses of 15 microalgae exposed to excessive irradiance including ultraviolet radiation

    NARCIS (Netherlands)

    Janknegt, Paul J.; De Graaff, C. Marco; Van De Poll, Willem H.; Visser, Ronald J. W.; Rijstenbil, Jan W.; Buma, Anita G. J.

    2009-01-01

    Short-term photosensitivity and oxidative stress responses were compared for three groups of marine microalgae: Antarctic microalgae, temperate diatoms and temperate flagellates. In total, 15 low-light-acclimated species were exposed to simulated surface irradiance including ultraviolet radiation

  6. An Expanded UV Irradiance Database from TOMS Including the Effects of Ozone, Clouds, and Aerosol Attenuation

    Science.gov (United States)

    Herman, J.; Krotkov, N.

    2003-01-01

    The TOMS UV irradiance database (1978 to 2003) has been expanded to include five new products (noon irradiance at 305,310,324, and 380 nm, and noon erythemal-weighted irradiance), in addition to the existing erythemal daily exposure, that permit direct comparisons with ground-based measurements from spectrometers and broadband instruments. The new data are available on http://toms.gsfc.nasa.gov/>http://toms.gsfc.nasa.gov. Comparisons of the TOMS estimated irradiances with ground-based instruments are given along with a review of the sources of known errors, especially the recent improvements in accounting for aerosol attenuation. Trend estimations from the new TOMS irradiances permit the clear separation of changes caused by ozone and those caused by aerosols and clouds. Systematic differences in cloud cover are shown to be the most important factor in determining regional differences in UV radiation reaching the ground for locations at the same latitude (e.g., the summertime differences between Australia and the US southwest).

  7. Irradiation Programs and Test Plans to Assess High-Fluence Irradiation Assisted Stress Corrosion Cracking Susceptibility.

    Energy Technology Data Exchange (ETDEWEB)

    Teysseyre, Sebastien [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-03-01

    hydrogen water chemistry mitigation technology may decrease as fluence increases for high-stress intensity factors. This report describes a program plan to determine the efficiency of hydrogen water chemistry as a function of the stress intensity factor applied and fluence. The use of existing, available, materials and the generation of additional materials via irradiation in a research reactor are considered.

  8. Diversity: Including People with Disabilities in Outdoor Adventure Programs.

    Science.gov (United States)

    Sugerman, Deb

    1996-01-01

    Organizations that offer outdoor adventure activities can integrate programs to include individuals with disabilities. The paper describes how one organization includes diverse groups of people with and without disabilities in its outdoor activities, focusing on each member's strengths and encouraging cooperation. (SM)

  9. Estimating solar irradiance using genetic programming technique and meteorological records

    Directory of Open Access Journals (Sweden)

    Rami Al-Hajj

    2017-08-01

    Full Text Available Solar irradiance is one of the most important parameters that need to be estimated and modeled before engaging in any solar energy project. This article describes a non-linear regression model based on genetic programming technique for estimating solar irradiance in a specific region in the United Arab Emirates. The genetic programming is an evolutionary computing technique that enables automatic search for complex solutions. The best nonlinear modeling function that can estimate the global solar radiation on horizontal will be developed taking into account measured meteorological data. A reference approach to model the solar radiation is first presented. An enhanced approach is then presented which consists of multi nonlinear functions of regression in a parallel structure where each function is designed to estimate the global solar irradiance in a specific seasonal period of the year. Statistical analysis measures have been used to evaluate the performance of the proposed approaches. The obtained results are comparable with the outcomes of models developed by other researchers in the field.

  10. Activity computer program for calculating ion irradiation activation

    Science.gov (United States)

    Palmer, Ben; Connolly, Brian; Read, Mark

    2017-07-01

    A computer program, Activity, was developed to predict the activity and gamma lines of materials irradiated with an ion beam. It uses the TENDL (Koning and Rochman, 2012) [1] proton reaction cross section database, the Stopping and Range of Ions in Matter (SRIM) (Biersack et al., 2010) code, a Nuclear Data Services (NDS) radioactive decay database (Sonzogni, 2006) [2] and an ENDF gamma decay database (Herman and Chadwick, 2006) [3]. An extended version of Bateman's equation is used to calculate the activity at time t, and this equation is solved analytically, with the option to also solve by numeric inverse Laplace Transform as a failsafe. The program outputs the expected activity and gamma lines of the activated material.

  11. Pulmonary Function After Treatment for Embryonal Brain Tumors on SJMB03 That Included Craniospinal Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Green, Daniel M., E-mail: daniel.green@stjude.org [Department of Epidemiology and Cancer Control, St. Jude Children' s Research Hospital, Memphis, Tennessee (United States); Merchant, Thomas E. [Department of Radiological Sciences, St. Jude Children' s Research Hospital, Memphis, Tennessee (United States); Billups, Catherine A. [Department of Biostatistics, St. Jude Children' s Research Hospital, Memphis, Tennessee (United States); Stokes, Dennis C. [Department of Pediatrics, University of Tennessee School of Medicine, Memphis, Tennessee (United States); Broniscer, Alberto [Department of Oncology, St. Jude Children' s Research Hospital, Memphis, Tennessee (United States); Bartels, Ute [Department of Haematology and Oncology, The Hospital for Sick Children, Toronto, Ontario (Canada); Chintagumpala, Murali [Department of Pediatric Medicine, Texas Children' s Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas (United States); Hassall, Timothy E. [Department of Haematology and Oncology, Royal Children' s Hospital, Brisbane (Australia); Gururangan, Sridharan [Department of Pediatrics, Duke University Medical Center, Durham, North Carolina (United States); McCowage, Geoffrey B. [Department of Pediatrics, Children' s Hospital at Westmead, Sydney (Australia); Heath, John A. [Children' s Cancer Center, Royal Children' s Hospital Melbourne, Melbourne (Australia); Cohn, Richard J. [Department of Clinical Oncology, Sydney Children' s Hospital, Sydney (Australia); Fisher, Michael J. [Department of Pediatrics, Children' s Hospital of Philadelphia, Philadelphia, Pennsylvania (United States); Srinivasan, Ashok [Department of Bone Marrow Transplantation & Cellular Therapy, St. Jude Children' s Research Hospital, Memphis, Tennessee (United States); Robinson, Giles W.; Gajjar, Amar [Department of Oncology, St. Jude Children' s Research Hospital, Memphis, Tennessee (United States)

    2015-09-01

    Purpose: The treatment of children with embryonal brain tumors (EBT) includes craniospinal irradiation (CSI). There are limited data regarding the effect of CSI on pulmonary function. Methods: Protocol SJMB03 enrolled patients 3 to 21 years of age with EBT. Pulmonary function tests (PFTs) (forced expiratory volume in 1 second [FEV{sub 1}] and forced vital capacity [FVC] by spirometry, total lung capacity [TLC] by nitrogen washout or plethysmography, and diffusing capacity of the lung for carbon monoxide corrected for hemoglobin [DLCO{sub corr}]) were obtained. Differences between PFTs obtained immediately after the completion of CSI and 24 or 60 months after the completion of treatment (ACT) were compared using exact Wilcoxon signed-rank tests and repeated-measures models. Results: Between June 24, 2003, and March 1, 2010, 303 eligible patients (spine dose: ≤2345 cGy, 201; >2345 cGy, 102; proton beam, 20) were enrolled, 260 of whom had at least 1 PFT. The median age at diagnosis was 8.9 years (range, 3.1-20.4 years). The median thoracic spinal radiation dose was 23.4 Gy (interquartile range [IQR], 23.4-36.0 Gy). The median cyclophosphamide dose was 16.0 g/m{sup 2} (IQR, 15.7-16.0 g/m{sup 2}). At 24 and 60 months ACT, DLCO{sub corr} was <75% predicted in 23% (27/118) and 25% (21/84) of patients, FEV{sub 1} was <80% predicted in 20% (34/170) and 29% (32/109) of patients, FVC was <80% predicted in 27% (46/172) and 28% (30/108) of patients, and TLC was <75% predicted in 9% (13/138) and 11% (10/92) of patients. DLCO{sub corr} was significantly decreased 24 months ACT (median difference [MD] in % predicted, 3.00%; P=.028) and 60 months ACT (MD in % predicted, 6.00%; P=.033) compared with the end of radiation therapy. These significant decreases in DLCO{sub corr} were also observed in repeated-measures models (P=.011 and P=.032 at 24 and 60 months ACT, respectively). Conclusions: A significant minority of EBT survivors experience PFT deficits after CSI

  12. Hearing of Personnel Included in the USAF Hearing Conservation Program

    Science.gov (United States)

    1976-02-01

    ORGNIZTIO NAE AN ADRES - 10. PROGRAM ELEMENT. PROJECT. TASK 9. PFORINGORGAIZAIONNAMEANDADDESSAREA ft WORK UNIT NUMBERS USAF School of Aerospace Medicine...0 0)~’ to (00w " 0 -q N~ m M VC0 CO~j 0 N 01) a)inUjU) tD -4 N o O 0 N 0 a) m m~0 di .. 0 alO1 O0- cn cO N - m -4N (0-00N (0 it) W N n N . o4Ca 0 0

  13. Craniospinal axis irradiation in children. Treatment in supine position including field verification as a prerequisite for anesthesia without intubation

    Energy Technology Data Exchange (ETDEWEB)

    Rades, D.; Holtzhauer, R.; Baumann, R.; Karstens, J.H. [Medizinische Hochschule Hannover (Germany). Klinik fuer Strahlentherapie und Spezielle Onkologie; Leuwer, M. [Medizinische Hochschule Hannover (Germany). Abt. Anaestesie

    1999-08-01

    Purpose: For craniospinal axis irradiation in young children sometimes anesthesia is required. In order to minimize risks from the anesthesist's point of view supine position would be preferable to standard prone position. In case of irradiation in supine position verification of the 3-field junction in the cervical region causes problems, because there is no direct visual control. For such situations the clinical application of a new technique is presented. Patients and Methods: For treatment planning a modern 3D planning system was necessary. Patient's positioning was done by using a vacuum-form body immobilizer and an integrated head mask. Radiation fields were placed only by table movements being calculated by the planning system in relation to a reference point at the patient's surface. In addition to common verification films specially prepared small films were used for the 3-field junction in the cervical region. These films were placed close to the patient for the whole time of each radiation session being exposed by every radiation field. Results: Two children (age 3 and 5 years, respectively) were irradiated as described. Twenty-eight of those specially prepared films were exposed. Two films (7%) had to be excluded because of inadequate exposure. An overlap of radiation fields was seen on 1 of the 26 remaining films (4%), whereas an unacceptable gap was not found. Acute skin reactions were comparable to those observed in patients being irradiated in standard prone position. Conclusion: The presented technique for craniospinal axis irradiation in supine position including field verification was not only precise and reproducable, but also comfortable and safe for the patient. We suggest it as a new option for craniospinal axis irradiation in children. (orig.) [German] Hintergrund: Fuer die Durchfuehrung einer Neuroachsenbestrahlung bei Kleinkindern ist mitunter eine Narkose erforderlich. Aus anaesthesiologischer Sicht waere zur Minimierung

  14. BSN Program Admittance Criteria: Should Emotional Intelligence Be Included?

    Science.gov (United States)

    Smith, Tanya

    2017-01-01

    Emotional intelligence refers to the ability to identify and monitor emotions and remain aware of how emotions affect thoughts and actions. Emotional intelligence has been discussed as a better predictor of personal and occupational success than performance on intellectual intelligence tests. Despite the importance of one's emotional intelligence, BSN (Bachelor of Science in Nursing) nursing schools routinely admit candidates based on the student's cumulative college course grade point average (GPA). Nursing is a profession that requires one's ability to empathize, care, and react in emotionally sound manners. Is the GPA enough to determine if a student will evolve into a professional nurse? This article will explore the routine admittance criteria for BSN nursing programs and propose the concept of using the emotional intelligence tool as an adjunct to the cumulative college course GPA. The emotional intelligence theory will be identified and applied to the nursing profession. © 2016 Wiley Periodicals, Inc.

  15. Information to Include in Curriculum Vitae | Cancer Prevention Fellowship Program

    Science.gov (United States)

    Applicants are encouraged to use their current curriculum vitae and to add any necessary information. Please include your name and a page number on each page of the curriculum vitae. Some of the information requested below will not be applicable to all individuals. Please do not print or type your information on this page. Personal Information Name (First middle last) Gender (optional) Race (optional) Date of birth Place of birth (city,

  16. Recent developments in the Sandia Laboratories' sewage sludge irradiation program

    Energy Technology Data Exchange (ETDEWEB)

    Sivinski, H.D.; Brandon, J.R.; Morris, M.E.; Neuhauser, K.S.; Ward, R.L.; McCaslin, B.; Smith, G.S.

    1977-11-01

    Pathogen reduction studies have shown that a 1 Mrad treatment (or less at elevated temperatures) is very effective in eliminating pathogenic bacteria and viable parasite ova in liquid sludges. Heat is effective in reducing levels not only of pathogenic bacteria and Ascaris ova, but viruses as well. Ammonia has been shown to be virucidal to poliovirus and several other enteric viruses. Sludge processing costs are seen to be marginally competitive with heat treatment for liquid sludges and relatively economical for composted or dried sludges. Physical/chemical effects studies have shown that the effects of irradiation of sludges on dewatering properties are not significant when compared to polymers, nor is the combined effect synergistic. Dried, irradiated undigested sludge has been shown to be of significant nutritional value when used as a feed supplement for sheep and cattle, as well as in agronomic uses. No significant harmful effects have been demonstrated in the feeding program thus far. Product enhancement studies are currently under way, including schemes for removing nitrogen from effluent streams for addition as ammonium salts to sludges.

  17. Byproducts Utilization Program: Sewage Sludge Irradiation Project. Progress report, July-December 1983

    Energy Technology Data Exchange (ETDEWEB)

    1984-12-01

    Engineering support for a demonstration-scale irradiator design included assisting the City of Albuquerque in preparing a comprehensive site plan for their proposed sludge handling and treatment facilities. The solar sludge dryer has been delivered to SNLA. A preliminary sludge drying experiment indicated the importance of optimizing stirring and air flow. Installation of instrumentation and mechanical equipment continued. The Sandia Irradiator for Dried Sewage Solids (SIDSS) was used to irradiate 23 tons of dried, digested sewage sludge for the New Mexico State University (NMSU) Department of Crop and Soil Sciences. Gamma Irradiation Facility (GIF) operations included irradiation of ground pork for Toxoplasma gondii inactivation experiments, irradiation of surgical supplies and soil samples. Beneficial Uses Shipping Systems (BUSS) cask activities included near completion of the two full-scale cask bodies. Work continued on the Cask Safety Analysis Report (SAR) including additional analyses to reconfigure the six strontium fluoride capsules and/or reduce the number of capsules accommodated. NMSU has indicated no regrowth of salmonellae occurred in the irradiated sludge stockpile, while salmonellae did regrow in the unirradiated stockpile. Analyses of raw and digested sewage sludge from the Albuquerque Waste Water Treatment Plant showed levels of Yersinia enterocolitica (a human pathogen of emerging significance) to be below detection limits.

  18. 34 CFR 263.4 - What training costs may a Professional Development program include?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What training costs may a Professional Development... GRANT PROGRAMS Professional Development Program § 263.4 What training costs may a Professional Development program include? (a) A Professional Development program may include, as training costs, assistance...

  19. Dose-dependent onset of regenerative program in neutron irradiated mouse skin.

    Directory of Open Access Journals (Sweden)

    Emiliano Fratini

    Full Text Available BACKGROUND: Tissue response to irradiation is not easily recapitulated by cell culture studies. The objective of this investigation was to characterize, the transcriptional response and the onset of regenerative processes in mouse skin irradiated with different doses of fast neutrons. METHODOLOGY/PRINCIPAL FINDINGS: To monitor general response to irradiation and individual animal to animal variation, we performed gene and protein expression analysis with both pooled and individual mouse samples. A high-throughput gene expression analysis, by DNA oligonucleotide microarray was done with three months old C57Bl/6 mice irradiated with 0.2 and 1 Gy of mono-energetic 14 MeV neutron compared to sham irradiated controls. The results on 440 irradiation modulated genes, partially validated by quantitative real time RT-PCR, showed a dose-dependent up-regulation of a sub-class of keratin and keratin associated proteins, and members of the S100 family of Ca(2+-binding proteins. Immunohistochemistry confirmed mRNA expression data enabled mapping of protein expression. Interestingly, proteins up-regulated in thickening epidermis: keratin 6 and S100A8 showed the most significant up-regulation and the least mouse-to-mouse variation following 0.2 Gy irradiation, in a concerted effort toward skin tissue regeneration. Conversely, mice irradiated at 1 Gy showed most evidence of apoptosis (Caspase-3 and TUNEL staining and most 8-oxo-G accumulation at 24 h post-irradiation. Moreover, no cell proliferation accompanied 1 Gy exposure as shown by Ki67 immunohistochemistry. CONCLUSIONS/SIGNIFICANCE: The dose-dependent differential gene expression at the tissue level following in vivo exposure to neutron radiation is reminiscent of the onset of re-epithelialization and wound healing and depends on the proportion of cells carrying multiple chromosomal lesions in the entire tissue. Thus, this study presents in vivo evidence of a skin regenerative program exerted independently

  20. Designing monitoring programs for chemicals of emerging concern in potable reuse ⋯ What to include and what not to include?

    KAUST Repository

    Drewes, Jorg

    2012-11-01

    This study discussed a proposed process to prioritize chemicals for reclaimed water monitoring programs, selection of analytical methods required for their quantification, toxicological relevance of chemicals of emerging concern regarding human health, and related issues. Given that thousands of chemicals are potentially present in reclaimed water and that information about those chemicals is rapidly evolving, a transparent, science-based framework was developed to guide prioritization of which compounds of emerging concern (CECs) should be included in reclaimed water monitoring programs. The recommended framework includes four steps: (1) compile environmental concentrations (e.g., measured environmental concentration or MEC) of CECs in the source water for reuse projects; (2) develop a monitoring trigger level (MTL) for each of these compounds (or groups thereof) based on toxicological relevance; (3) compare the environmental concentration (e.g., MEC) to the MTL; CECs with a MEC/MTL ratio greater than 1 should be prioritized for monitoring, compounds with a ratio less than \\'1\\' should only be considered if they represent viable treatment process performance indicators; and (4) screen the priority list to ensure that a commercially available robust analytical method is available for that compound. © IWA Publishing 2013.

  1. Control of Campylobacter jejuni in chicken breast meat by irradiation combined with modified atmosphere packaging including carbon monoxide.

    Science.gov (United States)

    Kudra, Li L; Sebranek, Joseph G; Dickson, James S; Mendonca, Aubrey F; Zhang, Q; Jackson-Davis, Armitra; Prusa, Kenneth J

    2012-10-01

    Campylobacter is one of the leading causes of human foodborne illnesses originating from meat and poultry products. Cross-contamination of this organism occurs in many poultry processing plants, and can occur in the kitchens and refrigerators of consumers. Therefore, new intervention strategies are needed for meat and poultry products to better protect consumers from this pathogen. Vacuum or modified atmosphere packaging is a common packaging technique used by the meat and poultry industry to extend the shelf life of meat products. In addition, irradiation has been well established as an antibacterial treatment to reduce pathogens on meat and poultry products. Irradiation in combination with high-CO(2) + CO modified atmosphere packaging (MAP) was investigated in this study for the control of Campylobacter jejuni in chicken breast meat. The radiation sensitivity (D(10)-value) of this foodborne pathogen in chicken breast meat was similar in vacuum or high-O(2) MAP (0.31 ± 0.01 kGy in vacuum packaging and 0.29 ± 0.03 kGy in MAP). C. jejuni survived in both vacuum and high-CO(2) MAP through 6 weeks of refrigerated storage. Irradiation was effective for eliminating C. jejuni from meat or poultry packaged in vacuum or MAP, and should reduce the chance of cross-contamination in retail stores or home kitchens. However, irradiated off-odor and sour aroma were observed for raw, irradiated chicken breast packaged with either vacuum or MAP. Therefore, additional means to mitigate quality changes appear necessary for these products.

  2. 34 CFR 86.100 - What must the IHE's drug prevention program include?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What must the IHE's drug prevention program include? 86.100 Section 86.100 Education Office of the Secretary, Department of Education DRUG AND ALCOHOL ABUSE PREVENTION Institutions of Higher Education § 86.100 What must the IHE's drug prevention program include? The...

  3. 10 CFR Appendix D to Part 73 - Physical Protection of Irradiated Reactor Fuel in Transit, Training Program Subject Schedule

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Physical Protection of Irradiated Reactor Fuel in Transit... Irradiated Reactor Fuel in Transit, Training Program Subject Schedule Pursuant to the provision of § 73.37 of... reactor fuel is required to assure that individuals used as shipment escorts have completed a training...

  4. Prior Irradiation Results in Elevated Programmed Cell Death Protein 1 (PD-1) in T Cells.

    Science.gov (United States)

    Li, Deguan; Chen, Renxiang; Wang, Yi-Wen; Fornace, Albert J; Li, Heng-Hong

    2017-11-07

    In this study we addressed the question whether radiation-induced adverse effects on T cell activation are associated with alterations of T cell checkpoint receptors. Expression levels of checkpoint receptors on T cell subpopulations were analyzed at multiple post-radiation time points ranging from one to four weeks in mice receiving a single fraction of 1 or 4 Gy of γ-ray. T cell activation associated metabolic changes were assessed. Our results showed that prior irradiation resulted in significant elevated expression of Programmed Cell Death Protein 1 (PD-1) in both CD4+ and CD8+ populations, at all three post-radiation time points. T cells with elevated PD-1 mostly were either central memory or naïve cells. In addition, the feedback induction of PD-1 expression in activated T cells declined after radiation. Taken together, the elevated PD-1 level observed at weeks after radiation exposure is connected to T cell dysfunction. Recent preclinical and clinical studies have showed that a combination of radiotherapy and T cell checkpoint blockade immunotherapy including targeting the PD-L1/PD-1 axis may potentiate the antitumor response. Understanding the dynamic changes in PD-1 levels in T cells after radiation should help in the development of a more effective therapeutic strategy.

  5. Status of preliminary tests on innovative basic researches for HTTR irradiation programs

    Energy Technology Data Exchange (ETDEWEB)

    Arai, Taketoshi [Oarai Research Establishment, Japan Atomic Energy Research Institute JAERI, Ibaraki-ken (Japan); Itoh, Hisayoshi [Takasaki Research Establishment, JAERI, Gunma-ken (Japan); Terai, Takayuki [University of Tokyo, Tokyo (Japan); Ishino, Shiori [Tokai University, Kanagawa-ken (Japan)

    1998-09-01

    Innovative basic researches using the HTTR concern with the basic science and applied technology which are associated with high temperature radiation environments. Proposed research themes constitute a wide variety of scientific and technological interests in the fields of new material development, fusion technology, radiation chemistry and high temperature technology. In order to demonstrate scientific feasibility and advantages in HTTR irradiations, JAERI has been conducting the preliminary tests on some selected subjects. Studies on high-Tc oxide superconductor samples irradiated by fast neutrons and annealed at higher temperatures has shown significantly improved superconducting properties. Implantation with P{sup +} ions into polycrystalline SiC samples at high temperatures up to 1200C have been found to be favorable in reducing residual defects. Candidates ceramic-based composites for structural components have been selected for characterizing micro/mesoscopic structural changes due to neutron irradiation and heat treatments. These preliminary tests are providing the technical bases for HTTR irradiation programs to be conducted in cooperation with domestic and foreign researchers. 6 refs.

  6. 36 CFR 1223.14 - What elements must a vital records program include?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What elements must a vital... RECORDS ADMINISTRATION RECORDS MANAGEMENT MANAGING VITAL RECORDS § 1223.14 What elements must a vital records program include? To achieve compliance with this section, an agency's vital records program must...

  7. Efficacy of an Individualized Prevention Program Including Social Media Support on University Students with Gingivitis

    National Research Council Canada - National Science Library

    Carlos Alberto Serrano Méndez; Karen Andrea Avendaño Calderón; Paula Andrea Moreno Caro

    2017-01-01

    ...: Thirty-eight students with gingivitis participated in a program that included: Individualized oral hygiene instruction, professional removal of plaque and calculus and, recall and support on oral hygiene through the use of social media...

  8. Comprehensive Adolescent Health Programs That Include Sexual and Reproductive Health Services: A Systematic Review

    Science.gov (United States)

    Parekh, Jenita; Tunçalp, Özge; Turke, Shani; Blum, Robert William

    2014-01-01

    We systematically reviewed peer-reviewed and gray literature on comprehensive adolescent health (CAH) programs (1998–2013), including sexual and reproductive health services. We screened 36 119 records and extracted articles using predefined criteria. We synthesized data into descriptive characteristics and assessed quality by evidence level. We extracted data on 46 programs, of which 19 were defined as comprehensive. Ten met all inclusion criteria. Most were US based; others were implemented in Egypt, Ethiopia, and Mexico. Three programs displayed rigorous evidence; 5 had strong and 2 had modest evidence. Those with rigorous or strong evidence directly or indirectly influenced adolescent sexual and reproductive health. The long-term impact of many CAH programs cannot be proven because of insufficient evaluations. Evaluation approaches that take into account the complex operating conditions of many programs are needed to better understand mechanisms behind program effects. PMID:25320876

  9. Food irradiation

    Energy Technology Data Exchange (ETDEWEB)

    1987-02-28

    A brief article examines the controversy over food irradiation regarding the wholesomeness of irradiated food, its microbiological safety, loss of vitamins and changes in flavour. The benefits of food irradiation are also outlined including the destruction of certain food-borne pathogens and the prolongation of the shelf-life of food by killing pests and delaying the deterioration process.

  10. Analysis of Core Physics Experiments on Irradiated BWR MOX Fuel in REBUS Program

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Toru; Ando, Yoshihira [Japan Nuclear Energy Safety Organization, Safety Standard Division, Tokyo (Japan); Hayashi, Yamato [Toshiba Corporation, Power System Company, Yokohama (Japan)

    2008-07-01

    As part of analyses of experimental data of a critical core containing a irradiated BWR MOX test bundle in the REBUS program, depletion calculations was performed for the BWR MOX fuel assemblies from that the MOX test rods were selected by using a general purpose neutronics code system SRAC. The core analyses were carried out using SRAC and a continuous energy Monte Carlo code MVP. The calculated k{sub eff}s were compared with those of the core containing a fresh MOX fuel bundle in the program. The SRAC-diffusion calculation underestimates k{sub eff}s of the both cores by 1.0 to 1.3 %dk and the k{sub eff}s of MVP are 1.001. The difference in k{sub eff} between the irradiated BWR MOX test bundle core and the fresh MOX one is 0.4 %dk in the SRAC-diffusion calculation and 0.0 %dk in the MVP calculation. The calculated fission rate distributions are in good agreement with the measurement in the SRAC-diffusion and MVP calculations. The calculated neutron flux distributions are also in good agreement with the measurement. The calculated burnup reactivity in the both calculations well reproduce the measurements. (authors)

  11. 29 CFR 1472.215 - What must I include in my drug-free awareness program?

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false What must I include in my drug-free awareness program? 1472.215 Section 1472.215 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND... of drug abuse in the workplace; (b) Your policy of maintaining a drug-free workplace; (c) Any...

  12. 29 CFR 94.215 - What must I include in my drug-free awareness program?

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true What must I include in my drug-free awareness program? 94.215 Section 94.215 Labor Office of the Secretary of Labor GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE... inform employees about— (a) The dangers of drug abuse in the workplace; (b) Your policy of maintaining a...

  13. 31 CFR 20.215 - What must I include in my drug-free awareness program?

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false What must I include in my drug-free awareness program? 20.215 Section 20.215 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than...

  14. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Applications for grants... Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Grants for Exchange of Information § 17.255 Applications for grants for programs which include construction projects. In addition to the documents and...

  15. Integrative Biological Chemistry Program Includes the Use of Informatics Tools, GIS and SAS Software Applications

    Science.gov (United States)

    D'Souza, Malcolm J.; Kashmar, Richard J.; Hurst, Kent; Fiedler, Frank; Gross, Catherine E.; Deol, Jasbir K.; Wilson, Alora

    2015-01-01

    Wesley College is a private, primarily undergraduate minority-serving institution located in the historic district of Dover, Delaware (DE). The College recently revised its baccalaureate biological chemistry program requirements to include a one-semester Physical Chemistry for the Life Sciences course and project-based experiential learning…

  16. Status of Post Irradiation Examination of FCAB and FCAT Irradiation Capsules

    Energy Technology Data Exchange (ETDEWEB)

    Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Fuel Cycle Research and Development (FCRD); Yamamoto, Yukinori [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Fuel Cycle Research and Development (FCRD); Howard, Richard H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Fuel Cycle Research and Development (FCRD)

    2016-09-29

    A series of irradiation programs are ongoing to address the need for determining the radiation tolerance of FeCrAl alloys. These irradiation programs, deemed the FCAT and FCAB irradiation programs, use the High Flux Isotope Reactor (HFIR) to irradiate second generation wrought FeCrAl alloys and early-generation powder-metallurgy (PM) oxide dispersion-strengthened (ODS) FeCrAl alloys. Irradiations have been or are being performed at temperatures of 200°C, 330°C, and 550°C from doses of 1.8 dpa up to 16 dpa. Preliminary post-irradiation examination (PIE) on low dose (<2 dpa) irradiation capsules of tensile specimens has been performed. Analysis of co-irradiated SiC thermometry have shown reasonable matching between the nominal irradiation temperatures and the target irradiation temperatures. Room temperature tensile tests have shown typical radiation-induced hardening and embrittlement at irradiations of 200°C and 330°C, but a propensity for softening when irradiated to 550°C for the wrought alloys. The PM-ODS FeCrAl specimens showed less hardening compared to the wrought alloys. Future PIE includes high temperature tensile tests on the low dose irradiation capsules as well as the determination of reference fracture toughness transition temperature, To, in alloys irradiated to 7 dpa and higher.

  17. 20 CFR 627.220 - Coordination with programs under title IV of the Higher Education Act including the Pell grant...

    Science.gov (United States)

    2010-04-01

    ... the Higher Education Act including the Pell grant program. 627.220 Section 627.220 Employees' Benefits... of the Higher Education Act including the Pell grant program. (a) Coordination. Financial assistance programs under title IV of the Higher Education Act of 1965, as amended (HEA) (the Pell Grant program, the...

  18. Transportation R and D included in thermal and mechanical sciences program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    Argonne National Laboratory is a multiprogram research and development laboratory operated by The University of Chicago for the US Department of Energy. At Argonne, applied research in thermal and mechanical sciences is performed within the Thermal and Mechanical Sciences Section of the Energy Technology Division. Current program areas include compact evaporators and condensers for the process and transportation industries, ice slurries for district cooling, advanced fluids for improved heat transfer and reduced pressure drop, flow-induced vibration and flow distribution in shell-and-tube heat exchangers, and dynamics and control of maglev systems. In general, the objective of the research is to extend the technology base in each of these areas and to facilitate its application in solving problems of importance to US industries and utilities. This is accomplished by developing validated design correlations and predictive methods. The staff of the Thermal and Mechanical Sciences Section have extensive experimental and analytical experience in heat transfer, multiphase flow, structural dynamics and control, fluid-structure interaction, transient flow and mixing, thermally driven flows, and flow visualization using ultra-high-speed video. Large, general-purpose test facilities and smaller, single-purpose test apparatuses are available for experiments and component design evaluation. A world-class capability in the study of flow-induced vibrations exists within the Section. Individual fact sheets, describing currently active research program areas, related facilities, and listing, as a contact, the principal investigator, are included.

  19. Body Image and quality of life of senior citizens included in a cardiac rehabilitation program

    Directory of Open Access Journals (Sweden)

    Fernanda Vargas Amaral

    2013-12-01

    Full Text Available Most people who have to live with some kind of disease tend to adopt healthy habits and create new ways of seeing themselves. The aim of this study is to explore the relationship between the index of quality of life and self perception of patients included in a cardiovascular rehabilitation program in Florianopolis/Brazil. The sample consists of 24 subjects of 62 ± 1.3 years of age, who have coronary artery disease. The Minnesota Living With Heart Failure Questionnaire (MLHFQ was used to assess the quality of life, and to identify the degree of body image discontentment the Stunkard and Sorensen questionnaire (1993 was applied. Statistical analysis was made through statistics programs and the software SPSS 11.0. The degree of association between variables was studied with Kendall test. It was verified that the higher the BMI and the current body shape, the greatest the degree of body image dissatisfaction. The emotional symptoms also appear to be significantly correlated with a desire for a smaller body shape and with indicators of lower quality of life (r = 0474 = 0735, p major 0.05. The physical symptoms were also considerably associated with the emotional symptoms. These results suggest that the variables concerning the quality of life are meaningful to significant body image and satisfaction, which seems to correlate with fewer emotional problems and better facing of the disease. Cardiovascular Rehabilitation Programs that implement physical activity in daily habits proves to be a suitable tool for improving these ailments in this post-acute phase

  20. Reliability Analysis of Brittle Material Structures - Including MEMS(?) - With the CARES/Life Program

    Science.gov (United States)

    Nemeth, Noel N.

    2002-01-01

    Brittle materials are being used, or considered, for a wide variety of high tech applications that operate in harsh environments, including static and rotating turbine parts. thermal protection systems, dental prosthetics, fuel cells, oxygen transport membranes, radomes, and MEMS. Designing components to sustain repeated load without fracturing while using the minimum amount of material requires the use of a probabilistic design methodology. The CARES/Life code provides a general-purpose analysis tool that predicts the probability of failure of a ceramic component as a function of its time in service. For this presentation an interview of the CARES/Life program will be provided. Emphasis will be placed on describing the latest enhancements to the code for reliability analysis with time varying loads and temperatures (fully transient reliability analysis). Also, early efforts in investigating the validity of using Weibull statistics, the basis of the CARES/Life program, to characterize the strength of MEMS structures will be described as as well as the version of CARES/Life for MEMS (CARES/MEMS) being prepared which incorporates single crystal and edge flaw reliability analysis capability. It is hoped this talk will open a dialog for potential collaboration in the area of MEMS testing and life prediction.

  1. A tool to include gamma analysis software into a quality assurance program.

    Science.gov (United States)

    Agnew, Christina E; McGarry, Conor K

    2016-03-01

    To provide a tool to enable gamma analysis software algorithms to be included in a quality assurance (QA) program. Four image sets were created comprising two geometric images to independently test the distance to agreement (DTA) and dose difference (DD) elements of the gamma algorithm, a clinical step and shoot IMRT field and a clinical VMAT arc. The images were analysed using global and local gamma analysis with 2 in-house and 8 commercially available software encompassing 15 software versions. The effect of image resolution on gamma pass rates was also investigated. All but one software accurately calculated the gamma passing rate for the geometric images. Variation in global gamma passing rates of 1% at 3%/3mm and over 2% at 1%/1mm was measured between software and software versions with analysis of appropriately sampled images. This study provides a suite of test images and the gamma pass rates achieved for a selection of commercially available software. This image suite will enable validation of gamma analysis software within a QA program and provide a frame of reference by which to compare results reported in the literature from various manufacturers and software versions. Copyright © 2015. Published by Elsevier Ireland Ltd.

  2. 78 FR 67369 - National Vaccine Injury Compensation Program: Addition to the Vaccine Injury Table to Include All...

    Science.gov (United States)

    2013-11-12

    ... HUMAN SERVICES Health Resources and Services Administration National Vaccine Injury Compensation Program: Addition to the Vaccine Injury Table to Include All Vaccines Against Seasonal Influenza AGENCY: Health... vaccines against seasonal influenza are covered under the National Vaccine Injury Compensation Program...

  3. Irradiation damage

    Energy Technology Data Exchange (ETDEWEB)

    Howe, L.M

    2000-07-01

    There is considerable interest in irradiation effects in intermetallic compounds from both the applied and fundamental aspects. Initially, this interest was associated mainly with nuclear reactor programs but it now extends to the fields of ion-beam modification of metals, behaviour of amorphous materials, ion-beam processing of electronic materials, and ion-beam simulations of various kinds. The field of irradiation damage in intermetallic compounds is rapidly expanding, and no attempt will be made in this chapter to cover all of the various aspects. Instead, attention will be focused on some specific areas and, hopefully, through these, some insight will be given into the physical processes involved, the present state of our knowledge, and the challenge of obtaining more comprehensive understanding in the future. The specific areas that will be covered are: point defects in intermetallic compounds; irradiation-enhanced ordering and irradiation-induced disordering of ordered alloys; irradiation-induced amorphization.

  4. Including nonadditive genetic effects in mating programs to maximize dairy farm profitability.

    Science.gov (United States)

    Aliloo, H; Pryce, J E; González-Recio, O; Cocks, B G; Goddard, M E; Hayes, B J

    2017-02-01

    We compared the outcome of mating programs based on different evaluation models that included nonadditive genetic effects (dominance and heterozygosity) in addition to additive effects. The additive and dominance marker effects and the values of regression on average heterozygosity were estimated using 632,003 single nucleotide polymorphisms from 7,902 and 7,510 Holstein cows with calving interval and production (milk, fat, and protein yields) records, respectively. Expected progeny values were computed based on the estimated genetic effects and genotype probabilities of hypothetical progeny from matings between the available genotyped cows and the top 50 young genomic bulls. An index combining the traits based on their economic values was developed and used to evaluate the performance of different mating scenarios in terms of dollar profit. We observed that mating programs with nonadditive genetic effects performed better than a model with only additive effects. Mating programs with dominance and heterozygosity effects increased milk, fat, and protein yields by up to 38, 1.57, and 1.21 kg, respectively. The inclusion of dominance and heterozygosity effects decreased calving interval by up to 0.70 d compared with random mating. The average reduction in progeny inbreeding by the inclusion of nonadditive genetic effects in matings compared with random mating was between 0.25 to 1.57 and 0.64 to 1.57 percentage points for calving interval and production traits, respectively. The reduction in inbreeding was accompanied by an average of A$8.42 (Australian dollars) more profit per mating for a model with additive, dominance, and heterozygosity effects compared with random mating. Mate allocations that benefit from nonadditive genetic effects can improve progeny performance only in the generation where it is being implemented, and the gain from specific combining abilities cannot be accumulated over generations. Continuous updating of genomic predictions and mate

  5. Educational program in crisis management for cardiac surgery teams including high realism simulation.

    Science.gov (United States)

    Stevens, Louis-Mathieu; Cooper, Jeffrey B; Raemer, Daniel B; Schneider, Robert C; Frankel, Allan S; Berry, William R; Agnihotri, Arvind K

    2012-07-01

    Cardiac surgery demands effective teamwork for safe, high-quality care. The objective of this pilot study was to develop a comprehensive program to sharpen performance of experienced cardiac surgical teams in acute crisis management. We developed and implemented an educational program for cardiac surgery based on high realism acute crisis simulation scenarios and interactive whole-unit workshop. The impact of these interventions was assessed with postintervention questionnaires, preintervention and 6-month postintervention surveys, and structured interviews. The realism of the acute crisis simulation scenarios gradually improved; most participants rated both the simulation and whole-unit workshop as very good or excellent. Repeat simulation training was recommended every 6 to 12 months by 82% of the participants. Participants of the interactive workshop identified 2 areas of highest priority: encouraging speaking up about critical information and interprofessional information sharing. They also stressed the importance of briefings, early communication of surgical plan, knowing members of the team, and continued simulation for practice. The pre/post survey response rates were 70% (55/79) and 66% (52/79), respectively. The concept of working as a team improved between surveys (P = .028), with a trend for improvement in gaining common understanding of the plan before a procedure (P = .075) and appropriate resolution of disagreements (P = .092). Interviewees reported that the training had a positive effect on their personal behaviors and patient care, including speaking up more readily and communicating more clearly. Comprehensive team training using simulation and a whole-unit interactive workshop can be successfully deployed for experienced cardiac surgery teams with demonstrable benefits in participant's perception of team performance. Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  6. Algorithms and Programs for Strong Gravitational Lensing In Kerr Space-time Including Polarization

    Science.gov (United States)

    Chen, Bin; Kantowski, Ronald; Dai, Xinyu; Baron, Eddie; Maddumage, Prasad

    2015-05-01

    Active galactic nuclei (AGNs) and quasars are important astrophysical objects to understand. Recently, microlensing observations have constrained the size of the quasar X-ray emission region to be of the order of 10 gravitational radii of the central supermassive black hole. For distances within a few gravitational radii, light paths are strongly bent by the strong gravity field of the central black hole. If the central black hole has nonzero angular momentum (spin), then a photon’s polarization plane will be rotated by the gravitational Faraday effect. The observed X-ray flux and polarization will then be influenced significantly by the strong gravity field near the source. Consequently, linear gravitational lensing theory is inadequate for such extreme circumstances. We present simple algorithms computing the strong lensing effects of Kerr black holes, including the effects on polarization. Our algorithms are realized in a program “KERTAP” in two versions: MATLAB and Python. The key ingredients of KERTAP are a graphic user interface, a backward ray-tracing algorithm, a polarization propagator dealing with gravitational Faraday rotation, and algorithms computing observables such as flux magnification and polarization angles. Our algorithms can be easily realized in other programming languages such as FORTRAN, C, and C++. The MATLAB version of KERTAP is parallelized using the MATLAB Parallel Computing Toolbox and the Distributed Computing Server. The Python code was sped up using Cython and supports full implementation of MPI using the “mpi4py” package. As an example, we investigate the inclination angle dependence of the observed polarization and the strong lensing magnification of AGN X-ray emission. We conclude that it is possible to perform complex numerical-relativity related computations using interpreted languages such as MATLAB and Python.

  7. ALGORITHMS AND PROGRAMS FOR STRONG GRAVITATIONAL LENSING IN KERR SPACE-TIME INCLUDING POLARIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Bin; Maddumage, Prasad [Research Computing Center, Department of Scientific Computing, Florida State University, Tallahassee, FL 32306 (United States); Kantowski, Ronald; Dai, Xinyu; Baron, Eddie, E-mail: bchen3@fsu.edu [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, Norman, OK 73019 (United States)

    2015-05-15

    Active galactic nuclei (AGNs) and quasars are important astrophysical objects to understand. Recently, microlensing observations have constrained the size of the quasar X-ray emission region to be of the order of 10 gravitational radii of the central supermassive black hole. For distances within a few gravitational radii, light paths are strongly bent by the strong gravity field of the central black hole. If the central black hole has nonzero angular momentum (spin), then a photon’s polarization plane will be rotated by the gravitational Faraday effect. The observed X-ray flux and polarization will then be influenced significantly by the strong gravity field near the source. Consequently, linear gravitational lensing theory is inadequate for such extreme circumstances. We present simple algorithms computing the strong lensing effects of Kerr black holes, including the effects on polarization. Our algorithms are realized in a program “KERTAP” in two versions: MATLAB and Python. The key ingredients of KERTAP are a graphic user interface, a backward ray-tracing algorithm, a polarization propagator dealing with gravitational Faraday rotation, and algorithms computing observables such as flux magnification and polarization angles. Our algorithms can be easily realized in other programming languages such as FORTRAN, C, and C++. The MATLAB version of KERTAP is parallelized using the MATLAB Parallel Computing Toolbox and the Distributed Computing Server. The Python code was sped up using Cython and supports full implementation of MPI using the “mpi4py” package. As an example, we investigate the inclination angle dependence of the observed polarization and the strong lensing magnification of AGN X-ray emission. We conclude that it is possible to perform complex numerical-relativity related computations using interpreted languages such as MATLAB and Python.

  8. 34 CFR 84.215 - What must I include in my drug-free awareness program?

    Science.gov (United States)

    2010-07-01

    ... awareness program to inform employees about— (a) The dangers of drug abuse in the workplace; (b) Your policy... assistance programs; and (d) The penalties that you may impose upon them for drug abuse violations occurring in the workplace. (Authority: E.O.s 12549 and 12689; 20 U.S.C. 1082, 1094, 1221e-3 and 3474; and Sec...

  9. Irradiation Facilities at CERN

    CERN Document Server

    Gkotse, Blerina; Carbonez, Pierre; Danzeca, Salvatore; Fabich, Adrian; Garcia, Alia, Ruben; Glaser, Maurice; Gorine, Georgi; Jaekel, Martin, Richard; Mateu,Suau, Isidre; Pezzullo, Giuseppe; Pozzi, Fabio; Ravotti, Federico; Silari, Marco; Tali, Maris

    2017-01-01

    CERN provides unique irradiation facilities for applications in many scientific fields. This paper summarizes the facilities currently operating for proton, gamma, mixed-field and electron irradiations, including their main usage, characteristics and information about their operation. The new CERN irradiation facilities database is also presented. This includes not only CERN facilities but also irradiation facilities available worldwide.

  10. 25 CFR 170.623 - How are IRR Program projects and activities included in a self-governance agreement?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How are IRR Program projects and activities included in a self-governance agreement? 170.623 Section 170.623 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE... self-governance agreement? To include an IRR Program project or activity in a self-governance agreement...

  11. [Michigan Technological University Pre-Service Teacher Enhancement Program]. [Includes a copy of the Student Guide

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, C.S.; Yarroch, W.L.

    1993-04-27

    The Michigan Technological University Teacher Education Program received funding from the US Department of Energy for the purpose of providing capable and suitably inclined, MTU Engineering and Science students a chance to explore high school level science and mathematics teaching as a career option. Ten undergraduate students were selected from nominations and were paired with mentor teachers for the study. This report covers the experience of the first ten nominees and their participation in the program.

  12. Simulated selection responses for breeding programs including resistance and resilience to parasites in Creole goats

    NARCIS (Netherlands)

    Gunia, M.; Phocas, F.; Gourdine, J.L.; Bijma, P.; Mandonnet, N.

    2013-01-01

    The Creole goat is a local breed used for meat production in Guadeloupe (French West Indies). As in other tropical countries, improvement of parasite resistance is needed. In this study, we compared predicted selection responses for alternative breeding programs with or without parasites resistance

  13. 77 FR 61012 - Expansion of Importer Self-Assessment Program To Include Qualified Importers of Focused...

    Science.gov (United States)

    2012-10-05

    ..., and to discuss the scope and methodology of the self-testing plan developed by the company. Companies... assessment methodology used by the company; the testing methodology; the frequency of self-testing activities... conducted at least annually. ( www.cbp.gov/xp/cgov/trade/trade_programs/importer_self_assessment/ ). Once...

  14. Program Review - Geothermal Exploration and Assessment Technology Program; Including a Report of the Reservoir Engineering Technical Advisory Group

    Energy Technology Data Exchange (ETDEWEB)

    Nielson, Dennis L., ed.

    1979-12-01

    In 1978, The Division of Geothermal Energy of the Department of Energy established the Geothermal Exploration and Assessment Technology Program. The purpose of this program is to ''provide assistance to the Nation's industrial community by helping to remove technical and associated economic barriers which presently inhibit efforts to bring geothermal electric power production and direct heat application on line''. In the near term this involves the adaptation of exploration and assessment techniques from the mineral and petroleum industry to geothermal applications. In the near to far term it involves the development of new technology which will improve the cost effectiveness of geothermal exploration.

  15. NSUF Irradiated Materials Library

    Energy Technology Data Exchange (ETDEWEB)

    Cole, James Irvin [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    The Nuclear Science User Facilities has been in the process of establishing an innovative Irradiated Materials Library concept for maximizing the value of previous and on-going materials and nuclear fuels irradiation test campaigns, including utilization of real-world components retrieved from current and decommissioned reactors. When the ATR national scientific user facility was established in 2007 one of the goals of the program was to establish a library of irradiated samples for users to access and conduct research through competitively reviewed proposal process. As part of the initial effort, staff at the user facility identified legacy materials from previous programs that are still being stored in laboratories and hot-cell facilities at the INL. In addition other materials of interest were identified that are being stored outside the INL that the current owners have volunteered to enter into the library. Finally, over the course of the last several years, the ATR NSUF has irradiated more than 3500 specimens as part of NSUF competitively awarded research projects. The Logistics of managing this large inventory of highly radioactive poses unique challenges. This document will describe materials in the library, outline the policy for accessing these materials and put forth a strategy for making new additions to the library as well as establishing guidelines for minimum pedigree needed to be included in the library to limit the amount of material stored indefinitely without identified value.

  16. The case for including reach as a key element of program theory.

    Science.gov (United States)

    Montague, Steve; Porteous, Nancy L

    2013-02-01

    This paper suggests that there is a need to build reach in the logic models and results frameworks of public health initiatives. A lack of explicit thinking about reach in logic models can lead to problems such as narrow/constricted understanding of impacts chain, favoring of 'narrow and efficient' initiatives over 'wide and engaging' initiatives and biased thinking against equity considerations. An alternative approach described in this paper that explicitly considers reach demonstrates that an explicit description of reach in program theory and results logic depictions can improve equity in health and social systems. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Including everyone: A peer learning program that works for under-represented minorities?

    Directory of Open Access Journals (Sweden)

    Jacques van der Meer

    2013-04-01

    Full Text Available Peer learning has long been recognised as an effective way to induct first-year students into the academic skills required to succeed at university. One recognised successful model that has been extensively researched is the Supplemental Instruction (SI model; it has operated in the US since the mid-1970s. This model is commonly known in Australasia as the Peer Assisted Study Sessions (PASS program. Although there is a considerable amount of research into SI and PASS, very little has been published about the impact of peer learning on different student groups, for example indigenous and other ethnic groups. This article reports on the results from one New Zealand university of the effectiveness of PASS for Māori and Pasifika students. The questions this article seeks to address are whether attendance of the PASS program results in better final marks for these two groups of students, and whether the number of sessions attended has an impact on the final marks.

  18. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false May Self-Governance Tribes include IHS construction... OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Purpose and Scope § 137.275 May Self-Governance Tribes include IHS construction programs in a construction project agreement or in a funding...

  19. Advanced theoretical and experimental studies in automatic control and information systems. [including mathematical programming and game theory

    Science.gov (United States)

    Desoer, C. A.; Polak, E.; Zadeh, L. A.

    1974-01-01

    A series of research projects is briefly summarized which includes investigations in the following areas: (1) mathematical programming problems for large system and infinite-dimensional spaces, (2) bounded-input bounded-output stability, (3) non-parametric approximations, and (4) differential games. A list of reports and papers which were published over the ten year period of research is included.

  20. 76 FR 9283 - Medicaid Program; Payment Adjustment for Provider-Preventable Conditions Including Health Care...

    Science.gov (United States)

    2011-02-17

    ... base of an OPPC, we propose to define OPPC to include, at a minimum, wrong surgical or other invasive... experience serious injury and/or death if they undergo erroneous surgical or other invasive procedures and.... Under these NCDs, Medicare does not cover a particular surgical or other invasive procedure to treat a...

  1. Palliative sedation for cancer patients included in a home care program: a retrospective study.

    Science.gov (United States)

    Calvo-Espinos, Claudio; Ruiz de Gaona, Estefania; Gonzalez, Cristina; Ruiz de Galarreta, Lucia; Lopez, Cristina

    2015-06-01

    Palliative sedation is a common treatment in palliative care. The home is a difficult environment for research, and there are few studies about sedation at home. Our aim was to analyze this practice in a home setting. We conducted a retrospective cross-sectional descriptive study in a home cohort during 2011. The inclusion criteria were as follows: 18 years or older and enrolled in the Palliative Home Care Program (PHCP) with advanced cancer. The variables employed were: sex, age, primary tumor location, and place of death. We also registered indication, type, drug and dose, awareness of diagnosis and prognosis, consent, survival, presence or absence of rales, painful mouth, and ulcers in patients sedated at home. We also collected the opinions of family members and professionals about the suffering of sedated patients. A total of 446 patients (56% at home) of the 617 admitted to the PHCP between January and December of 2011 passed away. The typical patient in our population was a 70-year-old man with a lung tumor. Some 35 (14%) home patients required sedation, compared to 93 (49%) at the hospital. The most frequent indication was delirium (70%), with midazolam the most common drug (mean dose, 40 mg). Survival was around three days. Rales were frequent (57%) as well as awareness of diagnosis and prognosis (77 and 71%, respectively). Perception of suffering after sedation was rare among relatives (17%) and professionals (8%). In most cases, the decision was made jointly by professionals and family members. Our study confirmed the role of palliative sedation as an appropriate therapeutic tool in the home environment.

  2. Analysis of the behavior under irradiation of high burnup nuclear fuels with the computer programs FRAPCON and FRAPTRAN

    Energy Technology Data Exchange (ETDEWEB)

    Reis, Regis; Silva, Antonio Teixeira e, E-mail: teixeira@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-11-01

    The objective of this paper is to verify the validity and accuracy of the results provided by computer programs FRAPCON-3.4a and FRAPTRAN-1.4, used in the simulation process of the irradiation behavior of Pressurized Water Reactors (PWR) fuel rods, in steady-state and transient operational conditions at high burnup. To achieve this goal, the results provided by these computer simulations are compared with experimental data available in the database FUMEX III. Through the results, it was found that the computer programs used have a good ability to predict the operational behavior of PWR fuel rods in high burnup steady-state conditions and under the influence of Reactivity Initiated Accident (RIA). (author)

  3. Modelling property changes in graphite irradiated at changing irradiation temperature

    CSIR Research Space (South Africa)

    Kok, S

    2011-01-01

    Full Text Available A new method is proposed to predict the irradiation induced property changes in nuclear; graphite, including the effect of a change in irradiation temperature. The currently used method; to account for changes in irradiation temperature, the scaled...

  4. A Call to Include Severe Combined Immunodeficiency in Newborn Screening Program

    Directory of Open Access Journals (Sweden)

    Raz Somech

    2014-01-01

    Full Text Available Quantification of the T cell receptor excision circles (TRECs has recently emerged as a useful non-invasive clinical and research tool to investigate thymic activity. It allows the identification of T cell production by the thymus. Quantification of TREC copies has recently been implemented as the preferred test to screen neonates with severe combined immunodeficiency (SCID or significant lymphopenia. Neonatal genetic screening for SCID is highly important in countries with high rates of consanguinous marriages, such as Israel, and can be used for early diagnosis, enabling prompt therapeutic intervention that will save lives and improve the outcome of these patients. TREC measurement is also applicable in clinical settings where T cell immunity is involved, including any T cell immunodeficiencies, HIV infection, the aging process, autoimmune diseases, and immune reconstitution after bone marrow transplantation.

  5. Guide for Operational Configuration Management Program including the adjunct programs of design reconstitution and material condition and aging management. Part 2

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    This standard presents program criteria and implementation guidance for an operational configuration management program for DOE nuclear and non-nuclear facilities. This Part 2 includes chapters on implementation guidance for operational configuration management, implementation guidance for design reconstitution, and implementation guidance for material condition and aging management. Appendices are included on design control, examples of design information, conduct of walkdowns, and content of design information summaries.

  6. 45 CFR 287.130 - Can NEW Program activities include job market assessments, job creation and economic development...

    Science.gov (United States)

    2010-10-01

    ... assessments, job creation and economic development activities? 287.130 Section 287.130 Public Welfare... creation and economic development activities? (a) A Tribe may conduct job market assessments within its NEW Program. These might include the following: (1) Consultation with the Tribe's economic development staff...

  7. Experiences of Students with Specific Learning Disorder (Including ADHD) in Online College Degree Programs: A Phenomenological Study

    Science.gov (United States)

    Bunch, Seleta LeAnn

    2016-01-01

    Enrollment in online degree programs is rapidly expanding due to the convenience and affordability offered to students and improvements in technology. The purpose of this hermeneutical phenomenological study was to understand the shared experiences of students with documented specific learning disorders (including Attention-Deficit/Hyperactivity…

  8. 12 CFR 303.46 - Financial education programs that include the provision of bank products and services.

    Science.gov (United States)

    2010-01-01

    ... principles of personal financial management, banking operations, or the benefits of saving for the future... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Financial education programs that include the provision of bank products and services. 303.46 Section 303.46 Banks and Banking FEDERAL DEPOSIT INSURANCE...

  9. Geothermal Exploration and Assessment Technology Program (review), including a report of the Reservoir Engineering Technical Advisory Group

    Energy Technology Data Exchange (ETDEWEB)

    Nielson, D.L. (ed.)

    1979-12-01

    The FY 1979 Program, recommended seismic surveys in conjunction with DOE/DGE's industry coupled program in the Northern Basin and Range Province, and the objectives of the Marina del Rey conference are presented. Final reports of six committees which met to define the state-of-the-art in geothermal exploration and to recommend exploration technology development are included. These committees are: structure, stratigraphy, and igneous processes; exploration architecture; electrical methods; seismic methods; thermal methods; water/rock interaction; and reservoir engineering. (MHR)

  10. Irradiation subassembly

    Science.gov (United States)

    Seim, O.S.; Filewicz, E.C.; Hutter, E.

    1973-10-23

    An irradiation subassembly for use in a nuclear reactor is described which includes a bundle of slender elongated irradiation -capsules or fuel elements enclosed by a coolant tube and having yieldable retaining liner between the irradiation capsules and the coolant tube. For a hexagonal bundle surrounded by a hexagonal tube the yieldable retaining liner may consist either of six segments corresponding to the six sides of the tube or three angular segments each corresponding in two adjacent sides of the tube. The sides of adjacent segments abut and are so cut that metal-tometal contact is retained when the volume enclosed by the retaining liner is varied and Springs are provided for urging the segments toward the center of the tube to hold the capsules in a closely packed configuration. (Official Gazette)

  11. Specific balance training included in an endurance-resistance exercise program improves postural balance in elderly patients undergoing haemodialysis.

    Science.gov (United States)

    Frih, Bechir; Mkacher, Wajdi; Jaafar, Hamdi; Frih, Ameur; Ben Salah, Zohra; El May, Mezry; Hammami, Mohamed

    2018-04-01

    The purpose of this study was to evaluate the effects of 6 months of specific balance training included in endurance-resistance program on postural balance in haemodialysis (HD) patients. Forty-nine male patients undergoing HD were randomly assigned to an intervention group (balance training included in an endurance-resistance training, n = 26) or a control group (resistance-endurance training only, n = 23). Postural control was assessed using six clinical tests; Timed Up and Go test, Tinetti Mobility Test, Berg Balance Scale, Unipodal Stance test, Mini-Balance Evaluation Systems Test and Activities Balance Confidence scale. All balance measures increased significantly after the period of rehabilitation training in the intervention group. Only the Timed Up and Go, Berg Balance Scale, Mini-Balance Evaluation Systems Test and Activities Balance Confidence scores were improved in the control group. The ranges of change in these tests were greater in the balance training group. In HD patients, specific balance training included in a usual endurance-resistance training program improves static and dynamic balance better than endurance-resistance training only. Implications for rehabilitation Rehabilitation using exercise in haemodialysis patients improved global mobility and functional abilities. Specific balance training included in usual endurance resistance training program could lead to improved static and dynamic balance.

  12. GIF++: A new CERN Irradiation Facility to test large-area particle detectors for the High-Luminosity LHC program

    CERN Document Server

    Guida, Roberto

    2016-01-01

    The high-luminosity LHC (HL-LHC) upgrade is setting a new challenge for particle detector technologies. The increase in luminosity will produce a higher particle background with respect to present conditions. To study performance and stability of detectors at LHC and future HL-LHC upgrades, a new dedicated facility has been built at CERN: the new Gamma Irradiation Facility (GIF++). The GIF++ is a unique place where high energy charged particle beams (mainly muons) are combined with gammas from a 14 TBq 137Cesium source which simulates the background radiation expected at the LHC experiments. Several centralized services and infrastructures are made available to the LHC detector community to facilitate the different R&D; programs.

  13. Description of a multifaceted rehabilitation program including overground gait training for a child with cerebral palsy: A case report.

    Science.gov (United States)

    Farrell, Elizabeth; Naber, Erin; Geigle, Paula

    2010-01-01

    This case describes the outcomes of a multifaceted rehabilitation program including body weight-supported overground gait training (BWSOGT) in a nonambulatory child with cerebral palsy (CP) and the impact of this treatment on the child's functional mobility. The patient is a nonambulatory 10-year-old female with CP who during an inpatient rehabilitation stay participated in direct, physical therapy 6 days per week for 5 weeks. Physical therapy interventions included stretching of her bilateral lower extremities, transfer training, bed mobility training, balance training, kinesiotaping, supported standing in a prone stander, two trials of partial weight-supported treadmill training, and for 4 weeks, three to five times per week, engaged in 30 minutes of BWSOGT using the Up n' go gait trainer, Lite Gait Walkable, and Rifton Pacer gait trainer. Following the multifaceted rehabilitation program, the patient demonstrated increased step initiation, increased weight bearing through bilateral lower extremities, improved bed mobility, and increased participation in transfers. The child's Gross Motor Functional Measure (GMFM) scores increased across four dimensions and her Physical Abilities and Mobility Scale (PAMS) increased significantly. This case report illustrates that a multifaceted rehabilitation program including BWSOGT was an effective intervention strategy to improve functional mobility in this nonambulatory child with CP.

  14. MSTor: A program for calculating partition functions, free energies, enthalpies, entropies, and heat capacities of complex molecules including torsional anharmonicity

    Science.gov (United States)

    Zheng, Jingjing; Mielke, Steven L.; Clarkson, Kenneth L.; Truhlar, Donald G.

    2012-08-01

    We present a Fortran program package, MSTor, which calculates partition functions and thermodynamic functions of complex molecules involving multiple torsional motions by the recently proposed MS-T method. This method interpolates between the local harmonic approximation in the low-temperature limit, and the limit of free internal rotation of all torsions at high temperature. The program can also carry out calculations in the multiple-structure local harmonic approximation. The program package also includes six utility codes that can be used as stand-alone programs to calculate reduced moment of inertia matrices by the method of Kilpatrick and Pitzer, to generate conformational structures, to calculate, either analytically or by Monte Carlo sampling, volumes for torsional subdomains defined by Voronoi tessellation of the conformational subspace, to generate template input files, and to calculate one-dimensional torsional partition functions using the torsional eigenvalue summation method. Catalogue identifier: AEMF_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEMF_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 77 434 No. of bytes in distributed program, including test data, etc.: 3 264 737 Distribution format: tar.gz Programming language: Fortran 90, C, and Perl Computer: Itasca (HP Linux cluster, each node has two-socket, quad-core 2.8 GHz Intel Xeon X5560 “Nehalem EP” processors), Calhoun (SGI Altix XE 1300 cluster, each node containing two quad-core 2.66 GHz Intel Xeon “Clovertown”-class processors sharing 16 GB of main memory), Koronis (Altix UV 1000 server with 190 6-core Intel Xeon X7542 “Westmere” processors at 2.66 GHz), Elmo (Sun Fire X4600 Linux cluster with AMD Opteron cores), and Mac Pro (two 2.8 GHz Quad-core Intel Xeon

  15. A Practical Irradiance Model for Bifacial PV Modules: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Marion, Bill; MacAlpine, Sara; Deline, Chris; Asgharzadeh, Amir; Toor, Fatima; Riley, Daniel; Stein, Joshua; Hansen, Clifford

    2017-06-15

    A model, suitable for a row or multiple rows of photovoltaic (PV) modules, is presented for estimating the backside irradiance for bifacial PV modules. The model, which includes the effects of shading by the PV rows, is based on the use of configuration factors (CFs) to determine the fraction of a source of irradiance that is received by the backside of the PV module. Backside irradiances are modeled along the sloped height of the PV module, but assumed not to vary along the length of the PV row. The backside irradiances are corrected for angle-of-incidence losses and may be added to the front side irradiance to determine the total irradiance resource for the PV cell. Model results are compared with the measured backside irradiances for NREL and Sandia PV systems, and with results when using the RADIANCE ray tracing program.

  16. Development and utilization of irradiational capsule - Mechanical and thermal performance analysis and development of design program on the cylindrical structures with multi-holes

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Shin; Choi, M. H.; Shin, D. S. [Chungnam National University, Taejon (Korea)

    2000-04-01

    Irradiation tests in the research reactor are used with the specially designed capsules for irradiation test and loop. Accordingly, suitable instrumented capsule for HANARO must be designed and manufactured. To satisfy the requirements of users and to conduct irradiation test effectively, the accurate informations on the thermal and mechanical characteristics of capsule should be understood. The structural analysis results show that stress characteristics of the cylinder with multi-holes is not significantly effected by the sizes of specimen hole, numbers of specimen and eccentric characteristics. The thermal and structural analysis of the capsule with multi-holes under thermal loading shows that the peak temperature in the circular cylinder is occurred in the specimens inserted in the center or specimen holes and is significantly effected by gap size between the holder and the external tube. In this study, CAPSYS program is developed by interfacing finite element analysis program, ANSYS with graphic user interface program, VISUAL C++. This program will be useful on the design and safety analysis of the capsule for material irradiation test. 20 refs., 37 figs., 9 tabs. (Author)

  17. On-Going International Research Program on Irradiated Concrete Conducted by DOE, EPRI and Japan Research Institutions. Roadmap, Achievements and Path Forward

    Energy Technology Data Exchange (ETDEWEB)

    Le Pape, Yann [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Rosseel, Thomas M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-10-01

    The Joint Department of Energy (DOE)-Electric Power Research Institute (EPRI) Program (Light Water Reactor Sustainability (LWRS) Program–Material Pathway–Concrete and Long-Term Operation (LTO) Program) and US Nuclear Regulatory Commission (NRC) research studies aim at understanding the most prominent degradation modes and their effects on the long-term operation of concrete structures to nuclear power generation. Based on the results of the Expanded Materials Degradation Analysis (EMDA), (NUREG/CR-7153, ORNL/TM-2011/545), irradiated concrete and alkali-silica reaction (ASR)-affected concrete structures are the two prioritized topics of on-going research. This report focuses specifically on the topic of irradiated concrete and summarizes the main accomplishments obtained by this joint program, but also provides an overview of current relevant activities domestically and internationally. Possible paths forward are also suggested to help near-future orientation of this program.

  18. Report on the program of 4 K irradiation of insulating materials for the Superconducting Super Collider

    Energy Technology Data Exchange (ETDEWEB)

    Spindel, A.

    1993-07-01

    This report is intended to serve as an aid to material selection. The results reported herein are the product of a careful investigation and can be used with confidence in their validity. The selection of materials based on this data, however, is not the responsibility of the author. This report will not approve or disapprove any specific material for use in the Super Collider. The author of this report does not assume any design responsibility or responsibility for material selection for any application. It is, therefore, very important that those with design responsibility use this report wisely. For this reason, the following informational guide to the material selection process has been provided. There are several issues to take into account when evaluating a material for radiation resistance. It is very important that the design criteria and operating loads for the application be known. For many applications the actual loading, and therefore required properties, are unknown. Certain materials have empirically been used successfully in a similar application and those materials have often been selected on that basis. Both percent degradation and the magnitude of the actual properties after irradiation need to be considered. Consider the scenario where two materials are being compared that both have acceptable properties after exposure to 10{sup 9} rads. It is preferable to choose the material with less degradation because degradation tends to be a threshold phenomena with properties declining rapidly with dose after a certain threshold dose. The properties of the initially strong material, therefore, will be extremely sensitive to dose in that dose range and slight magnet-to-magnet differences in dose may, depending on the application, lead to performance variations.

  19. The Role of Endothelial Dysfunction Markers in Pregnant Women with Chorion Detachment, Included in the Program of Auxiliary Reproductive Technologies

    Directory of Open Access Journals (Sweden)

    Natalya Lytvyn

    2017-10-01

    Full Text Available An urgent medical and social problem is the restoration of reproductive function of womenwho suffer from infertility, which became possible due to auxiliary reproductive technologies. Women with induced pregnancy make thegroup of a high-risk on miscarriage, due to interrelated processes –immunological disorders and endothelial dysfunction that occur in the body of pregnant women after the use of extracorporal fertilization programs, and can lead to the chorion detachment and the formation of subchorionic hematomas. The purpose of the study is to determine the role of endothelial dysfunction as one of the leading factors that determine the development of a local non-progressive chorion detachment in infertile patients included in the program of auxiliary reproductive technologies. Materials and methods. We have examined 130 pregnant women, who were divided into groups: the control group included 30 women, whose pregnancy occurred in the natural cycle and with uncomplicated gestational course; the main group – 50 patients with induced pregnancy and risk factors of the occurrence of chorion detachment, who wereperformed the proposed pre-gravidapreparation; the comparative group – 50 pregnant women who received a standard scheme of pregnancy management before and after in-vitro fertilization. A general clinical examination, ultrasound examination, homocysteine level determination, endothelin-1 and nitrogen oxide metabolites were performed. Results. In women included into the program of auxiliary reproductive technologies with local chorion detachment were recorded changes of vascular endothelial function with a possible increase in endothelin-1 production and a decrease of the nitric oxidesynthesis. During the induced pregnancy with the presence of subchorionic hematoma, an increase of the level of endothelium-damaging factor of homocysteine was noted. Conclusions.This study identifies the parameters that reflect the main links of endothelial

  20. Research in radiobiology. Annual report of work in progress in the internal irradiation program

    Energy Technology Data Exchange (ETDEWEB)

    1979-03-31

    The toxicity, retention, biological effects, distribution, decorporation and measuring techniques of radionuclides are discussed. Calculations of trabecular bone formation rates from tetracycline labeling is included. The characteristics of trabecular bone in the Rhesus monkey are discussed. Studies on the early retention and distribution of radium 224 in beagles are included. Studies on the decorporation of plutonium and americium in dogs by DTPA and salicylic acid are presented.

  1. HTGR Fuels and Core Development Program. Quarterly progress report for the period ending August 31, 1977. [Graphite and fuel irradiation; fission product release

    Energy Technology Data Exchange (ETDEWEB)

    1977-09-01

    The work reported includes studies of reactions between core materials and coolant impurities, basic fission product transport mechanisms, core graphite development and testing, the development and testing of recyclable fuel systems, and physics and fuel management studies. Materials studies include irradiation capsule tests of both fuel and graphite. Experimental procedures and results are discussed and data are presented.

  2. HTGR fuels and core development program. Quarterly progress report for period ending February 29, 1976. [Graphite and fuel irradiation; fission product release

    Energy Technology Data Exchange (ETDEWEB)

    1976-03-31

    The work reported includes studies of reactions between core materials and coolant impurities, basic fission product transport mechanisms, core graphite development and testing, the development and testing of recyclable fuel systems, and physics and fuel management studies. Materials studies include irradiation capsule tests of both fuel and graphite. Experimental procedures and results are discussed and the data are presented in tables, graphs, and photographs.

  3. 45 CFR 284.30 - What information must the State include in its assessment of the impact of the TANF program(s) in...

    Science.gov (United States)

    2010-10-01

    ... program(s); (2) The total amount of State and Tribal spending on TANF cash assistance payments; (3) The... Food Stamp Program or other State supportive and assistance programs; (4) The proportion of students...

  4. Research in radiobiology. Annual report of work in progress in the internal irradiation program

    Energy Technology Data Exchange (ETDEWEB)

    Jee, W.S.S.

    1975-03-31

    Separate abstracts were prepared for 15 papers. In addition, twenty-three injection tables are presented for toxicity animals and test animals. The injection tables include the calculated average dose in rads to the skeleton at death for 13 actinides. (HLW)

  5. CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness.

    Science.gov (United States)

    Ahrends, Tomasz; Spanjaard, Aldo; Pilzecker, Bas; Bąbała, Nikolina; Bovens, Astrid; Xiao, Yanling; Jacobs, Heinz; Borst, Jannie

    2017-11-21

    CD4+ T cells optimize the cytotoxic T cell (CTL) response in magnitude and quality, by unknown molecular mechanisms. We here present the transcriptomic changes in CTLs resulting from CD4+ T cell help after anti-cancer vaccination or virus infection. The gene expression signatures revealed that CD4+ T cell help during priming optimized CTLs in expression of cytotoxic effector molecules and many other functions that ensured efficacy of CTLs throughout their life cycle. Key features included downregulation of PD-1 and other coinhibitory receptors that impede CTL activity, and increased motility and migration capacities. "Helped" CTLs acquired chemokine receptors that helped them reach their tumor target tissue and metalloprotease activity that enabled them to invade into tumor tissue. A very large part of the "help" program was instilled in CD8+ T cells via CD27 costimulation. The help program thus enhances specific CTL effector functions in response to vaccination or a virus infection. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Evaluation design of a reactivation care program to prevent functional loss in hospitalised elderly: A cohort study including a randomised controlled trial

    National Research Council Canada - National Science Library

    Asmus-Szepesi, Kirsten; Vreede, Paul; Nieboer, Anna; Wijngaarden, Jeroen; Bakker, Ton; Steyerberg, Ewout; Mackenbach, Johan

    2011-01-01

    ... patients by comparing a new intervention program to two usual care programs. Methods/Design. This study will include an effect, process and cost evaluation using a mixed methods design of quantitative and qualitative methods...

  7. The Effects of a Family Support Program Including Respite Care on Parenting Stress and Family Quality of Life Perceived by Primary Caregivers of Children with Disabilities in Korea

    Science.gov (United States)

    Sung, Minjung; Park, Jiyeon

    2012-01-01

    In this study, a family support program was carried out for primary caregivers of children with disabilities. The program included respite care, recreation programs, counseling, and social support coordination based on individual needs of each family. In order to verify the intervention effects, parenting stress and family quality of life were…

  8. Thorium utilization program progress report for January 1, 1974--June 30, 1975. [Reprocessing; refabrication; recycle fuel irradiations

    Energy Technology Data Exchange (ETDEWEB)

    Lotts, A.L.; Kasten, P.R.

    1976-05-01

    Work was carried out on the following: HTGR reprocessing development and pilot plant, refabrication development and pilot plant, recycle fuel irradiations, engineering and economic studies, and conceptual design of a commercial recycle plant. (DLC)

  9. [Study of the nutritional status of patients over 65 years included in the home care program in an urban population].

    Science.gov (United States)

    Muñoz Díaz, Belén; Arenas de Larriva, Antonio P; Molina-Recio, Guillermo; Moreno-Rojas, Rafael; Martínez de la Iglesia, Jorge

    2018-02-01

    To analyse the nutritional status of patients older than 65 years included in the home care program (PAD). Croos-sectional study. 3 urban health centers. 218 patients in the PAD. Mini Nutritional Assessment questionnaire (MNA) was applied. Sociodemographic, anthropometric, dependency, emotional and cognitive status and analytical parameters: 57 variables were collected. Possible associations were analysed by applying the chi square and variance analysis. The level of significance was considered to be Pnutritional status and older age, lower BMI, greater dependence on basic and instrumental activities of daily living and greater cognitive impairment. The lowest mean hemoglobin, albumin, and iron levels were also associated with malnutrition and risk of malnutrition. More than half of PAD patients are malnourished or at risk for it, and a high proportion of them some laboratory abnormality susceptible to be corrected. Most cognitive impairment and functional dependence are closely related to malnutrition; so patients with these characteristics should receive more attention from the nutritional point of view. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  10. Evaluation of 8-week body weight control program including sea tangle (Laminaria japonica) supplementation in Korean female college students

    OpenAIRE

    You, Jeong Soon; Sung, Min Jung; Chang, Kyung Ja

    2009-01-01

    This study was conducted to evaluate the effects of a body weight control program with supplementation of sea tangle (20 g/day) on 22 female college students. The contents of the program for 8 weeks contained diet therapy, exercise and behavioral modification through nutrition education. Body composition, dietary habit scores, serum lipid profiles, daily nutrient intakes and the quality of life were assessed at the beginning and at the end of the program. Average age of subjects and height we...

  11. 25 CFR 170.137 - What types of activities can a recreation, tourism, and trails program include?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What types of activities can a recreation, tourism, and... INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Recreation, Tourism and Trails § 170.137 What types of activities can a recreation, tourism, and...

  12. Ca analysis: An Excel based program for the analysis of intracellular calcium transients including multiple, simultaneous regression analysis☆

    Science.gov (United States)

    Greensmith, David J.

    2014-01-01

    Here I present an Excel based program for the analysis of intracellular Ca transients recorded using fluorescent indicators. The program can perform all the necessary steps which convert recorded raw voltage changes into meaningful physiological information. The program performs two fundamental processes. (1) It can prepare the raw signal by several methods. (2) It can then be used to analyze the prepared data to provide information such as absolute intracellular Ca levels. Also, the rates of change of Ca can be measured using multiple, simultaneous regression analysis. I demonstrate that this program performs equally well as commercially available software, but has numerous advantages, namely creating a simplified, self-contained analysis workflow. PMID:24125908

  13. Ca analysis: an Excel based program for the analysis of intracellular calcium transients including multiple, simultaneous regression analysis.

    Science.gov (United States)

    Greensmith, David J

    2014-01-01

    Here I present an Excel based program for the analysis of intracellular Ca transients recorded using fluorescent indicators. The program can perform all the necessary steps which convert recorded raw voltage changes into meaningful physiological information. The program performs two fundamental processes. (1) It can prepare the raw signal by several methods. (2) It can then be used to analyze the prepared data to provide information such as absolute intracellular Ca levels. Also, the rates of change of Ca can be measured using multiple, simultaneous regression analysis. I demonstrate that this program performs equally well as commercially available software, but has numerous advantages, namely creating a simplified, self-contained analysis workflow. Copyright © 2013 The Author. Published by Elsevier Ireland Ltd.. All rights reserved.

  14. Expanding the Lessons Learned Program to Include Corps Support Command Commanders and Theater Army Area Command Commanders

    Science.gov (United States)

    1989-03-10

    INTRODUCTION The Oral History Program’s purpose is to supplement oFficial histories , to isolate successful command, leadership and managerial...of -the program is to capture the experience of senior leaders in the areas of command, leadership , and management . The individual is interviewed...used to gain insight into command and management techniques and to further research in military history . In June of 1984, the Chief of Staff, General

  15. The status and prospects of the irradiation tests at HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Man Soon; Choo, Kee Nam; Yang, Seong Woo; Park, Sang Jun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    The integrity assessment of NPP and the extension of lifetime are being considered as important issue, and so the irradiation tests for the structural materials and fuels of NPP should necessarily be conducted. And, the capability of irradiation test is important because Korea participates in developing SFR and VHTR while the development of future nuclear systems is going on to obtain new energy sources all over the world. To effectively support the R and D for new nuclear systems at HANARO, the advanced irradiation technologies such as high-temperature irradiation, instrumentation, and long-term irradiation are being developed. In addition, the researches on the irradiation characteristics of super-conductor materials and new chemical materials are being progressed as a part of fundamental research. Korea is conducting R and D programs relevant to new nuclear systems including research reactor, future nuclear system such as VHTR, SFR and fusion reactor system. In addition, research on the irradiation characteristics of super-conductor materials and new electronic materials is being conducted as a part of fundamental research. Irradiation tests in HANARO are mostly related to the R and D relevant to the ageing management and safety evaluation of NPP and development of the future nuclear system and production of design data of research reactor. The HANARO irradiation capsule system has been developed and actively utilized for the irradiation testing of fuels and materials. The irradiation tests of materials up to the present have been performed usually at temperatures below 300 .deg. C, at which the RPV of PWR materials is being operated. As the irradiation tests of the materials and fuels for a Gen-IV nuclear system are recently required and the development of new research reactors is going on, the capsules for high- and low-temperature irradiation are being developed at HANARO.

  16. Components production and assemble of the irradiation capsule of the Surveillance Program of Materials of the nuclear power plant of Laguna Verde;Fabricacion de componentes y ensamble de la capsula de irradiacion del Programa de Vigilancia de Materiales de la central nuclear Laguna Verde

    Energy Technology Data Exchange (ETDEWEB)

    Medrano, A. [ININ, Departamento de Tecnologia de Materiales, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

    2009-07-01

    To predict the effects of the neutrons radiation and the thermal environment about the mechanical properties of the reactor vessel materials of the nuclear power plant of Laguna Verde, a surveillance program is implemented according to the outlines settled by Astm E185-02 -Standard practice for design of surveillance programs for light-water moderated nuclear power reactor vessels-. This program includes the installation of three irradiation capsules of similar materials to those of the reactor vessels, these samples are test tubes for mechanical practices of impact and tension. In the National Institute of Nuclear Research and due to the infrastructure as well as of the actual human resources of the Pilot Plant of Nuclear Fuel Assembles Production it was possible to realize the materials rebuilding extracted in 2005 of Unit 2 of nuclear power plant of Laguna Verde as well as the production, assemble and reassignment of the irradiation capsule made in 2006. At the present time the surveillance materials extracted in 2008 of Unit 1 of the nuclear power plant of Laguna Verde are reconstituting and the components are manufactured for the assembles of the irradiation capsule that will be reinstalled in the reactor vessel in 2010. The purpose of the present work is to describe the necessary components as well as its disposition during the assembles of the irradiation capsule for the surveillance program of the reactors vessel of the nuclear power plant of Laguna Verde. (Author)

  17. Pilot monitoring program: geologic input for the hillslope component (includes a discussion of Caspar Creek geology and geomorphology)

    Science.gov (United States)

    T. E. Spittler

    1995-01-01

    The California Department of Conservation, Division of Mines and Geology (DMG) is submitting this report and accompanying maps to the California Department of Forestry and Fire Protection (CDF) to fulfill Interagency Agreement number 8CA38400, Pilot Monitoring Program -- Geologic Input for the Hillslope Component. Under this agreement, DMG has assisted CDF in the...

  18. Intensive lifestyle intervention including high-intensity interval training program improves insulin resistance and fasting plasma glucose in obese patients

    Directory of Open Access Journals (Sweden)

    Guillaume Marquis-Gravel

    2015-01-01

    Conclusion: Following a 9-month intensive lifestyle intervention combining HIIT and MedD counseling, obese subjects experienced significant improvements of FPG and insulin resistance. This is the first study to expose the effects of a long-term program combining HIIT and MedD on glycemic control parameters among obese subjects.

  19. Quick Reference Guide: Working with Stakeholders to Identify Potential Improvement Strategies for Program Improvement (Including the SSIP)

    Science.gov (United States)

    Center for IDEA Early Childhood Data Systems (DaSy), 2015

    2015-01-01

    This 2015 quick reference guide is designed to assist states in understanding what information needs to be available in order for stakeholders to assist in selecting potential improvement strategies that will increase capacity of Local Education Agencies (LEAs), Early Intervention Services (EIS) programs, and practitioners to improve results for…

  20. Building a Steganography Program Including How to Load, Process, and Save JPEG and PNG Files in Java

    Science.gov (United States)

    Courtney, Mary F.; Stix, Allen

    2006-01-01

    Instructors teaching beginning programming classes are often interested in exercises that involve processing photographs (i.e., files stored as .jpeg). They may wish to offer activities such as color inversion, the color manipulation effects archived with pixel thresholding, or steganography, all of which Stevenson et al. [4] assert are sought by…

  1. 77 FR 22790 - ``Low Income Levels'' Used for Various Health Professions and Nursing Programs Included in Titles...

    Science.gov (United States)

    2012-04-17

    ... HUMAN SERVICES Health Resources and Services Administration ``Low Income Levels'' Used for Various... backgrounds, or (3) individuals from ``low-income'' families. SUPPLEMENTARY INFORMATION: The various health..., public or private nonprofit schools which offer graduate programs in behavioral health and mental health...

  2. 76 FR 14417 - ``Low Income Levels'' Used for Various Health Professions and Nursing Programs Included in Titles...

    Science.gov (United States)

    2011-03-16

    ... HUMAN SERVICES Health Resources and Services Administration ``Low Income Levels'' Used for Various... backgrounds, or (3) individuals from ``low-income'' families. SUPPLEMENTARY INFORMATION: The various health..., public or private nonprofit schools which offer graduate programs in behavioral health and mental health...

  3. Evaluation of 8-week body weight control program including sea tangle (Laminaria japonica) supplementation in Korean female college students.

    Science.gov (United States)

    You, Jeong Soon; Sung, Min Jung; Chang, Kyung Ja

    2009-01-01

    This study was conducted to evaluate the effects of a body weight control program with supplementation of sea tangle (20 g/day) on 22 female college students. The contents of the program for 8 weeks contained diet therapy, exercise and behavioral modification through nutrition education. Body composition, dietary habit scores, serum lipid profiles, daily nutrient intakes and the quality of life were assessed at the beginning and at the end of the program. Average age of subjects and height were 20.8 years and 161.9 cm, respectively. After 8 weeks, there were significant reductions in body weight, body fat mass, percent body fat, waist-hip ratio and BMI. The dietary habit score such as a balanced diet, regularity of mealtime, overeating, eating while watching TV or using the computer and eating salty food were increased significantly. Serum lipid levels such as total cholesterol level, LDL-cholesterol level and triglyceride level were decreased but not significantly. There were decreases in intake of energy, protein and fat and increases in intakes of dietary fiber, folic acid, calcium and potassium from the beginning to the end of the program. There were significant improvements on subcomponents of quality of life; physical functioning, general-health and vitality. The limitation of this study was the fact that there was no control group, but an overall evaluation suggests the 8-week body weight control program consisting of diet therapy, exercise and behavioral modification with supplementation of sea tangle would be helpful to improve the body composition, dietary habits, daily nutrient intakes and quality of life in Korean female college students.

  4. Ultrasonic Transducer Irradiation Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Daw, Joshua [Idaho National Lab. (INL), Idaho Falls, ID (United States); Palmer, Joe [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Keller, Paul [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Montgomery, Robert [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chien, Hual-Te [Argonne National Lab. (ANL), Argonne, IL (United States); Kohse, Gordon [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Tittmann, Bernhard [Pennsylvania State Univ., University Park, PA (United States); Reinhardt, Brian [Pennsylvania State Univ., University Park, PA (United States); Rempe, Joy [Rempe and Associates, Idaho Falls, ID (United States)

    2015-02-01

    Ultrasonic technologies offer the potential for high-accuracy and -resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. Other ongoing efforts include an ultrasonic technique to detect morphology changes (such as crack initiation and growth) and acoustic techniques to evaluate fission gas composition and pressure. These efforts are limited by the lack of identified ultrasonic transducer materials capable of long term performance under irradiation test conditions. For this reason, the Pennsylvania State University (PSU) was awarded an ATR NSUF project to evaluate the performance of promising magnetostrictive and piezoelectric transducers in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 1021 n/cm2. The goal of this research is to characterize and demonstrate magnetostrictive and piezoelectric transducer operation during irradiation, enabling the development of novel radiation-tolerant ultrasonic sensors for use in Material Testing Reactors (MTRs). As such, this test is an instrumented lead test and real-time transducer performance data is collected along with temperature and neutron and gamma flux data. The current work bridges the gap between proven out-of-pile ultrasonic techniques and in-pile deployment of ultrasonic sensors by acquiring the data necessary to demonstrate the performance of ultrasonic transducers. To date, one piezoelectric

  5. DIADORIM: a Monte Carlo Program for liquid simulations including quantum mechanics and molecular mechanics (QM/MM) facilities: applications to liquid ethanol

    OpenAIRE

    Freitas,Luiz Carlos Gomide

    2009-01-01

    This paper presents a Metropolis Monte Carlo (MMC) computer program developed to simulate liquids and solutions including QM/MM facilities: the energy from intermolecular interactions is calculated with classical force field functions and the internal molecular energies are calculated using Quantum Chemistry methods. The following facilities were implemented: (i) the semiempirical MOPAC 6 quantum chemistry package was included as a subroutine of the main MMC simulation program; (ii) alternati...

  6. HTGR fuels and core development program. Quarterly progress report for the period ending February 28, 1978. [Graphite and fuel irradiation; fission product release

    Energy Technology Data Exchange (ETDEWEB)

    1978-03-01

    The work documented here includes the design, analysis, and testing of the reactor core and its components comprising the fuel elements, hexagonal reflector elements, plenum elements, neutron sources, control rods, and reserve shutdown material. Also included are studies of reactions between core materials and coolant impurities, basic fission product transport mechanisms, core graphite development and testing, the development and testing of recyclable fuel systems, and physics and fuel management studies. Materials studies include irradiation capsule tests of both fuel and graphite. Experimental procedures and results are discussed and, where appropriate, the data are presented in tables, graphs, and photographs.

  7. Pulmonary rehabilitation program including respiratory conditioning for chronic obstructive pulmonary disease (COPD): Improved hyperinflation and expiratory flow during tidal breathing.

    Science.gov (United States)

    Yoshimi, Kaku; Ueki, Jun; Seyama, Kuniaki; Takizawa, Makiko; Yamaguchi, Seiko; Kitahara, Eriko; Fukazawa, Shinji; Takahama, Yukiko; Ichikawa, Masako; Takahashi, Kazuhisa; Fukuchi, Yoshinosuke

    2012-06-01

    Pulmonary rehabilitation has generally relieved symptoms, strengthened exercise endurance and improved health-related quality of life (QOL) in patients with COPD, but recovery of pulmonary function remains questionable. This analysis of our innovative rehabilitation program is directed at documenting changes in patients' expiratory airflow limitation, pulmonary symptoms and QOL. This program is designed to provide "respiratory conditioning", a physical therapist-assisted intensive flexibility training that focuses on stretching and rib cage mobilization. Thirty-one patients with COPD who attended rehabilitation sessions at Juntendo University Hospital from 1999 to 2006 were analyzed. Pulmonary function, expiratory flow limitation during tidal breathing, six minute walk distance (6MWD), respiratory muscle strength, and St. George Respiratory Questionnaire (SGRQ) were measured before and after pulmonary rehabilitation. In participants ages 68±7 years, the FEV(1)% predicted was 39.3±15.7%. 6MWD, SGRQ and respiratory muscle strength were significantly improved after pulmonary rehabilitation. Although neither FEV(1)% predicted nor FEV(1)/FVC was affected to a significant extent, indicating little effect on airflow limitation, expiratory flow limitation in supine as well as seated during tidal breathing improved significantly. Moreover, rehabilitation significantly diminished TLC% predicted, FRC% predicted, RV% predicted and RV/TLC values, thus indicating a reduction of hyperinflation of the lungs at rest. The present results suggest that our rehabilitation program with respiratory conditioning significantly lowered the hyperinflation of lungs at rest as well as the expiratory flow limitation during tidal breathing. In patients with COPD, overall pulmonary function improved, exercise endurance increased and health-related QOL was enhanced.

  8. Phytosanitary Irradiation

    Directory of Open Access Journals (Sweden)

    Guy J. Hallman

    2016-01-01

    Full Text Available Phytosanitary treatments disinfest traded commodities of potential quarantine pests. Phytosanitary irradiation (PI treatments use ionizing radiation to accomplish this, and, since their international commercial debut in 2004, the use of this technology has increased by ~10% annually. Generic PI treatments (one dose is used for a group of pests and/or commodities, although not all have been tested for efficacy are used in virtually all commercial PI treatments, and new generic PI doses are proposed, such as 300 Gy, for all insects except pupae and adult Lepidoptera (moths. Fresh fruits and vegetables tolerate PI better than any other broadly used treatment. Advances that would help facilitate the use of PI include streamlining the approval process, making the technology more accessible to potential users, lowering doses and broadening their coverage, and solving potential issues related to factors that might affect efficacy.

  9. Effects of dentin surface treatments including Er,Cr:YSGG laser irradiation with different intensities on the push-out bond strength of the glass fiber posts to root dentin.

    Science.gov (United States)

    Kirmali, Omer; Kustarci, Alper; Kapdan, Alper; Er, Kursat

    2015-07-01

    Intra-canal post systems are commonly used to restore root-filled teeth. Bond strengths of the posts can be affected by various surface treatments of the post or the dentin. The aim of this study was to evaluate the effects of dentin surface treatments including erbium-chromium; yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser irradiation with different intensities on the push-out bond strength of the glass fiber posts to root dentin. Forty single-rooted human maxillary incisors were filled and post spaces were prepared. After these procedures, the specimens were divided randomly into four groups according to the dentin surface treatments, as follows: (i) untreated surface (control), (ii) 1W Er,Cr:YSGG laser application, (iii) 2W Er,Cr:YSGG laser application and (iv) 3W Er,Cr:YSGG laser application. Then the posts were cemented into the root canals using dual-cured resin cement. Bonded specimens were cut into 1-mm-thick slices and push-out tests were performed using a universal testing device. All specimens were loaded until fracture and the failure modes were evaluated with a stereomicroscope at 32× magnification. Representative specimens were analyzed by scanning electron microscopy. Data were analyzed using a one-way ANOVA, Tukey and Wilcoxon tests. The bond strength values ranged from 3.22-4.68 MPa. There were no statistically significant differences among the groups, regardless of the different levels. The coronal and middle levels of the post space had significantly higher bond strength values compared with the apical level (p fiber posts to the root canal dentin walls.

  10. 32 CFR Appendix B to Part 80 - Procedures for Special Educational Programs (Including Related Services) for Preschool Children...

    Science.gov (United States)

    2010-07-01

    ... (Including Related Services) for Preschool Children and Children With Disabilities (3-21 years Inclusive) B... Related Services) for Preschool Children and Children With Disabilities (3-21 years Inclusive) A... of a parent of each preschool child or child, evaluate all preschool children or children who are...

  11. Materials irradiation research in neutron science

    Energy Technology Data Exchange (ETDEWEB)

    Noda, Kenji; Oyama, Yukio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-11-01

    Materials irradiation researches are planned in Neutron Science Research Program. A materials irradiation facility has been conceived as one of facilities in the concept of Neutron Science Research Center at JAERI. The neutron irradiation field of the facility is characterized by high flux of spallation neutrons with very wide energy range up to several hundred MeV, good accessibility to the irradiation field, good controllability of irradiation conditions, etc. Extensive use of such a materials irradiation facility is expected for fundamental materials irradiation researches and R and D of nuclear energy systems such as accelerator-driven incineration plant for long-lifetime nuclear waste. In this paper, outline concept of the materials irradiation facility, characteristics of the irradiation field, preliminary technical evaluation of target to generate spallation neutrons, and materials researches expected for Neutron Science Research program are described. (author)

  12. 20 CFR 664.410 - Must local programs include each of the ten program elements listed in WIA section 129(c)(2) as...

    Science.gov (United States)

    2010-04-01

    ... school completion, including dropout prevention strategies; (2) Alternative secondary school offerings... 664.470; (5) Occupational skill training; (6) Leadership development opportunities, which include... individual service strategy. (WIA sec. 129(c)(2).) ...

  13. AGC-2 Specimen Post Irradiation Data Package Report

    Energy Technology Data Exchange (ETDEWEB)

    Windes, William Enoch [Idaho National Lab. (INL), Idaho Falls, ID (United States); Swank, W. David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rohrbaugh, David T. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cottle, David L. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-08-01

    This report documents results of the post-irradiation examination material property testing of the creep, control, and piggyback specimens from the irradiation creep capsule Advanced Graphite Creep (AGC)-2 are reported. This is the second of a series of six irradiation test trains planned as part of the AGC experiment to fully characterize the neutron irradiation effects and radiation creep behavior of current nuclear graphite grades. The AGC-2 capsule was irradiated in the Idaho National Laboratory Advanced Test Reactor at a nominal temperature of 600°C and to a peak dose of 5 dpa (displacements per atom). One-half of the creep specimens were subjected to mechanical stresses (an applied stress of either 13.8, 17.2, or 20.7 MPa) to induce irradiation creep. All post-irradiation testing and measurement results are reported with the exception of the irradiation mechanical strength testing, which is the last destructive testing stage of the irradiation testing program. Material property tests were conducted on specimens from 15 nuclear graphite grades using a similar loading configuration as the first AGC capsule (AGC-1) to provide easy comparison between the two capsules. However, AGC-2 contained an increased number of specimens (i.e., 487 total specimens irradiated) and replaced specimens of the minor grade 2020 with the newer grade 2114. The data reported include specimen dimensions for both stressed and unstressed specimens to establish the irradiation creep rates, mass and volume data necessary to derive density, elastic constants (Young’s modulus, shear modulus, and Poisson’s ratio) from ultrasonic time-of-flight velocity measurements, Young’s modulus from the fundamental frequency of vibration, electrical resistivity, and thermal diffusivity and thermal expansion data from 100–500°C. No data outliers were determined after all measurements were completed. A brief statistical analysis was performed on the irradiated data and a limited comparison between

  14. Development of integrated waste management options for irradiated graphite

    Directory of Open Access Journals (Sweden)

    Alan Wareing

    2017-08-01

    Full Text Available The European Treatment and Disposal of Irradiated Graphite and other Carbonaceous Waste project sought to develop best practices in the retrieval, treatment, and disposal of irradiated graphite including other irradiated carbonaceous waste such as structural material made of graphite, nongraphitized carbon bricks, and fuel coatings. Emphasis was given on legacy irradiated graphite, as this represents a significant inventory in respective national waste management programs. This paper provides an overview of the characteristics of graphite irradiated during its use, primarily as a moderator material, within nuclear reactors. It describes the potential techniques applicable to the retrieval, treatment, recycling/reuse, and disposal of these graphite wastes. Considering the lifecycle of nuclear graphite, from manufacture to final disposal, a number of waste management options have been developed. These options consider the techniques and technologies required to address each stage of the lifecycle, such as segregation, treatment, recycle, and ultimate disposal in a radioactive waste repository, providing a toolbox to aid operators and regulators to determine the most appropriate management strategy. It is noted that national waste management programs currently have, or are in the process of developing, respective approaches to irradiated graphite management. The output of the Treatment and Disposal of Irradiated Graphite and other Carbonaceous Waste project is intended to aid these considerations, rather than dictate them.

  15. Development of integrated waste management options for irradiated graphite

    Energy Technology Data Exchange (ETDEWEB)

    Wareing, Alan; Abrahamsen-Mills, Liam; Fowler, Linda; Jarvis, Richard; Banford, Anthony William [National Nuclear Laboratory, Warrington (United Kingdom); Grave, Michael [Doosan Babcock, Gateshead (United Kingdom); Metcalfe, Martin [National Nuclear Laboratory, Gloucestershire (United Kingdom); Norris, Simon [Radioactive Waste Management Limited, Oxon (United Kingdom)

    2017-08-15

    The European Treatment and Disposal of Irradiated Graphite and other Carbonaceous Waste project sought to develop best practices in the retrieval, treatment, and disposal of irradiated graphite including other irradiated carbonaceous waste such as structural material made of graphite, nongraphitized carbon bricks, and fuel coatings. Emphasis was given on legacy irradiated graphite, as this represents a significant inventory in respective national waste management programs. This paper provides an overview of the characteristics of graphite irradiated during its use, primarily as a moderator material, within nuclear reactors. It describes the potential techniques applicable to the retrieval, treatment, recycling/reuse, and disposal of these graphite wastes. Considering the lifecycle of nuclear graphite, from manufacture to final disposal, a number of waste management options have been developed. These options consider the techniques and technologies required to address each stage of the lifecycle, such as segregation, treatment, recycle, and ultimate disposal in a radioactive waste repository, providing a toolbox to aid operators and regulators to determine the most appropriate management strategy. It is noted that national waste management programs currently have, or are in the process of developing, respective approaches to irradiated graphite management. The output of the Treatment and Disposal of Irradiated Graphite and other Carbonaceous Waste project is intended to aid these considerations, rather than dictate them.

  16. Appraisal and analysis of opportunities for a joint DOE/DOD energy demonstration program. Final report. [Includes possible site information

    Energy Technology Data Exchange (ETDEWEB)

    Ziem, R.W.

    1980-05-01

    The basic objective of this study was to assess the potential for cooperative projects between the Department of Energy (DOE) and the Department of Defense (DOD) in areas concerned with the development of Total Energy (TE) Systems and to do the groundwork and liaison necessary to initiate those projects. The scope of the potential joint projects includes cooperative effort in the development and test of a variety of heat engines (prime movers) capable of utilizing coal as well as synthetic liquid fuels derived from coal and oil shale; as well as the indication of potential Military Department sites which would be suitable for the demonstration of TE systems based on a variety of such prime movers. In order to accomplish the objective of the study, it was necessary to review a large number of DOD studies and plans and to discuss the objective of the TETAS studies with a large number of Military Department people. The DOD recognizes the requirement for an assured energy supply and the need to learn how to use the synthetic fuels from coal and shale being developed by the DOE. The need to modify engine systems to adapt them to differing fuel characteristics and make those engines more flexible relative to the range of fuels they will accept is clear. What is not so clear is the fact that the DOD has a much greater opportunity to conserve energy in now inefficient facility operations than it has in mobility operations which must continue to stress mission and high performance. This report indicates guidelines for the conduct of joint projects between the DOE and the DOD which can aid both in meeting their energy objective.

  17. International Programs and Centers for Instruction, Research and Public Service in the Western States (Including Instruction in Less Common Foreign Languages).

    Science.gov (United States)

    Abbott, Frank C., Ed.

    Programs of education and research on international economy and trade, foreign cultures and languages, and other aspects of international affairs and located in the western states are listed in an annotated directory. The units are of varying types and include informal interdepartmental committees within academic institutions, well-established…

  18. Blood compounds irradiation process: assessment of absorbed dose using Fricke and Thermoluminescent dosimetric systems

    Energy Technology Data Exchange (ETDEWEB)

    Soares, Gabriela de Amorim; Squair, Peterson Lima; Pinto, Fausto Carvalho; Belo, Luiz Claudio Meira; Grossi, Pablo Andrade [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN-CNEN/MG), Belo Horizonte, MG (Brazil)], e-mail: gas@cdtn.br, e-mail: pls@cdtn.br, e-mail: fcp@cdtn.br, e-mail: lcmb@cdtn.br, e-mail: pabloag@cdtn.br

    2009-07-01

    The assessment of gamma absorbed doses in irradiation facilities allows the quality assurance and control of the irradiation process. The liability of dose measurements is assign to the metrological procedures adopted including the uncertainty evaluation. Fricke and TLD 800 dosimetric systems were used to measure absorbed dose in the blood compounds using the methodology presented in this paper. The measured absorbed doses were used for evaluating the effectiveness of the irradiation procedure and the gamma dose absorption inside the irradiation room of a gamma irradiation facility. The radiation eliminates the functional and proliferative capacities of donor T-lymphocytes, preventing Transfusion associated graft-versus-host disease (TA-GVHD), a possible complication of blood transfusions. The results show the applicability of such dosimetric systems in quality assurance programs, assessment of absorbed doses in blood compounds and dose uniformity assign to the blood compounds irradiation process by dose measurements in a range between 25 Gy and 100 Gy. (author)

  19. Prevention of diabetes in overweight/obese children through a family based intervention program including supervised exercise (PREDIKID project): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Arenaza, Lide; Medrano, María; Amasene, María; Rodríguez-Vigil, Beatriz; Díez, Ignacio; Graña, Manuel; Tobalina, Ignacio; Maiz, Edurne; Arteche, Edurne; Larrarte, Eider; Huybrechts, Inge; Davis, Catherine L; Ruiz, Jonatan R; Ortega, Francisco B; Margareto, Javier; Labayen, Idoia

    2017-08-10

    The global pandemic of obesity has led to an increased risk for prediabetes and type-2 diabetes (T2D). The aims of the current project are: (1) to evaluate the effect of a 22-week family based intervention program, including supervised exercise, on insulin resistance syndrome (IRS) risk in children with a high risk of developing T2D and (2) to identify the profile of microRNA in circulating exosomes and in peripheral blood mononuclear cells in children with a high risk of developing T2D and its response to a multidisciplinary intervention program including exercise. A total of 84 children, aged 8-12 years, with a high risk of T2D will be included and randomly assigned to control (N = 42) or intervention (N = 42) groups. The control group will receive a family based lifestyle education and psycho-educational program (2 days/month), while the intervention group will attend the same lifestyle education and psycho-educational program plus the exercise program (3 days/week, 90 min per session including warm-up, moderate to vigorous aerobic activities, and strength exercises). The following measurements will be evaluated at baseline prior to randomization and after the intervention: fasting insulin, glucose and hemoglobin A1c; body composition (dual-energy X-ray absorptiometry); ectopic fat (magnetic resonance imaging); microRNA expression in circulating exosomes and in peripheral blood mononuclear cells (MiSeq; Illumina); cardiorespiratory fitness (cardiopulmonary exercise testing); dietary habits and physical activity (accelerometry). Prevention and identification of children with a high risk of developing T2D could help to improve their cardiovascular health and to reduce the comorbidities associated with obesity. ClinicalTrials.gov, ID: NCT03027726 . Registered on 16 January 2017.

  20. Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors?

    Science.gov (United States)

    Alswaidi, F M; O'Brien, S J

    2010-11-01

    In January 2008, the Saudi Arabian health authority included mandatory testing for HIV, HBV and HCV viruses in the premarital screening program. Epidemiologically, there were few justifications for their inclusion as disease prevalences and distributions are poorly understood in the population. This study aims to provide information about HBV, HCV and HIV prevalences and risk factors for disease transmission and so produce evidence for informed decision-making on the inclusion of these infectious diseases in the screening program. This is a cross-sectional descriptive study embedded in the existing national premarital screening program for thalassaemia and sickle cell disease to estimate the prevalence of HIV, HBV and HCV infections (n=74,662 individuals), followed by a case-control study to identify risk factors responsible for infection transmission (n=540). The average HIV prevalence is 0.03%, 1.31% for HBV and 0.33% for HCV. Sharing personal belongings particularly razors, blood transfusions, cuts at barbershops and extramarital relationships showed the highest significant associations with the transmission of these viruses. The prevalences of HIV, HBV and HCV in Saudi Arabia are among the lowest worldwide. However, all the important risk factors associated with transmitting these viruses are significantly present in the Saudi community. Saudi Arabia is financially capable of screening for these infections in the mandatory premarital program and of providing medical care for the discovered cases, but focusing on the health education programs may offset the need to mandatory testing.

  1. Characterization program, management and isotopic inventory calculation, radiological and fuel thermal irradiated in nuclear power Cofrentes; Programa Caracterizacion Gestion y calculo del inventario isotopico, radiologico y termico del combustible irradiado en la Central Nuclear de Cofrentes

    Energy Technology Data Exchange (ETDEWEB)

    Albendea, M.; Diego, J. L. de; Urrea, M.

    2012-07-01

    Characterization is a very detailed and user-friendly program takes into account the history of irradiation individualized and real all the fuel, even taking into account the interim periods are periods of discharge and recharge cycles and which have not been used.

  2. Gas-Cooled Reactor Programs annual progress report for period ending December 31, 1973. [HTGR fuel reprocessing, fuel fabrication, fuel irradiation, core materials, and fission product distribution; GCFR fuel irradiation and steam generator modeling

    Energy Technology Data Exchange (ETDEWEB)

    Kasten, P.R.; Coobs, J.H.; Lotts, A.L.

    1976-04-01

    Progress is summarized in studies relating to HTGR fuel reprocessing, refabrication, and recycle; HTGR fuel materials development and performance testing; HTGR PCRV development; HTGR materials investigations; HTGR fuel chemistry; HTGR safety studies; and GCFR irradiation experiments and steam generator modeling.

  3. A water-based training program that include perturbation exercises to improve stepping responses in older adults: study protocol for a randomized controlled cross-over trial

    Directory of Open Access Journals (Sweden)

    Tsedek Irit

    2008-08-01

    Full Text Available Abstract Background Gait and balance impairments may increase the risk of falls, the leading cause of accidental death in the elderly population. Fall-related injuries constitute a serious public health problem associated with high costs for society as well as human suffering. A rapid step is the most important protective postural strategy, acting to recover equilibrium and prevent a fall from initiating. It can arise from large perturbations, but also frequently as a consequence of volitional movements. We propose to use a novel water-based training program which includes specific perturbation exercises that will target the stepping responses that could potentially have a profound effect in reducing risk of falling. We describe the water-based balance training program and a study protocol to evaluate its efficacy (Trial registration number #NCT00708136. Methods/Design The proposed water-based training program involves use of unpredictable, multi-directional perturbations in a group setting to evoke compensatory and volitional stepping responses. Perturbations are made by pushing slightly the subjects and by water turbulence, in 24 training sessions conducted over 12 weeks. Concurrent cognitive tasks during movement tasks are included. Principles of physical training and exercise including awareness, continuity, motivation, overload, periodicity, progression and specificity were used in the development of this novel program. Specific goals are to increase the speed of stepping responses and improve the postural control mechanism and physical functioning. A prospective, randomized, cross-over trial with concealed allocation, assessor blinding and intention-to-treat analysis will be performed to evaluate the efficacy of the water-based training program. A total of 36 community-dwelling adults (age 65–88 with no recent history of instability or falling will be assigned to either the perturbation-based training or a control group (no training

  4. Question: in a service including a radio pharmacy, a TEP scan unit and five classical examination rooms, what is the most irradiating post?; Question: dans un service comprenant une radio pharmacie, une unite tep scan et 5 salles d'examens classiques, quel est le poste le plus irradiant?

    Energy Technology Data Exchange (ETDEWEB)

    Costes, M.; Madrid, A.; Rasp, N. [Centre Hospitalier Universitaire de Bordeaux, Medecine Nucleaire, Hopital du Haut Leveque Bordeaux, 33 (France)

    2007-09-15

    The first results give the radio pharmacy as the most irradiating post with a non negligible dosimetry at extremities and not the PET one as it was first supposed. These dosimetry studies allow to optimize the daily practices and lead to a more rigorous follow up of the personnel dosimetry. (N.C.)

  5. 34 CFR 303.15 - Include; including.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Include; including. 303.15 Section 303.15 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EARLY INTERVENTION PROGRAM FOR INFANTS AND TODDLERS WITH...

  6. Accelerated partial breast irradiation in an Asian population: dosimetric findings and preliminary results of a multicatheter interstitial program

    Directory of Open Access Journals (Sweden)

    Koh YV

    2016-09-01

    Full Text Available Yaling Vicky Koh,1 Poh Wee Tan,1 Shaik Ahmad Buhari,2 Philip Iau,2 Ching Wan Chan,2 Liang Shen,3 Sing Huang Tan,4 Johann I-Hsiung Tang1 1Department of Radiation Oncology, National University Cancer Institute Singapore, 2Department of Surgery, National University Hospital, 3Department of Medicine, Biostatistics Unit, National University of Singapore, 4Department of Medical Oncology, National University Cancer Institute Singapore, Singapore Introduction: Accelerated partial breast irradiation (APBI using the multicatheter method has excellent cosmesis and low rates of long-term toxicity. However, there are few studies looking at the feasibility of this procedure and the outcomes in an Asian population. This study aims to look at outcomes at our hospital.Methods: We identified 121 patients treated with APBI at our center between 2008 and 2014. The median follow-up for our patient group was 30 months (range 3.7–66.5. The prescribed dose per fraction was 3.4 Gy in 10 fractions. In this study population, 71% of the patients were Chinese while 15% (n=19 were of other Asian ethnicity.Results: In this study, the median breast volume was 850 cc (range 216–2,108 with 59.5% (n=72 patients with a breast volume of <1,000 cc. The average planning target volume was 134 cc (range 28–324. The number of catheters used ranged from 8 to 25 with an average of 18 catheters used per patient. We achieved an average dose homogeneity index of 0.76 in our patients. The average D90(% was 105% and the average D90(Gy was 3.6 Gy per fraction. The median volume receiving 100% of the prescribed dose (V100 was 161.7 cc (range 33.9–330.1, 150% of the prescribed dose (V150 and 200% of the prescribed dose (V200 was 39.4 cc (range 14.6–69.6 and 14.72 cc (range 6.48–22.25, respectively. Our dosimetric outcomes were excellent even in patients with breast volume under 1,000 cc. There were no cases of grade 3 skin toxicity or acute pneumonitis. Two patients had a

  7. Status of irradiation technology development in JMTR

    Energy Technology Data Exchange (ETDEWEB)

    Inaba, Y.; Inoue, S.; Izumo, H.; Kitagishi, S.; Tsuchiya, K.; Saito, T.; Ishitsuka, E. [Japan Atomic Energy Agency (JAEA), Ibaraki (Japan)

    2008-11-15

    Irradiation Engineering Section of the Neutron Irradiation and Testing Reactor Centre was organised to development the new irradiation technology for the application at JMTR re-operation. The new irradiation engineering building was remoulded from the old RI development building, and was started to use from the end of September, 2008. Advanced in-situ instrumentation technology(high temperature multi-paired thermocouple, ceramic sensor,application of optical measurement), {sup 99}Mo production technology by new Mo solution irradiation method,recycling technology on used beryllium reflector, and so on are planned as the development of new irradiation technologies. The development will be also important for the education and training programs through the development of young generation in not only Japan but also Asian countries. In this report, as the status of the development the new irradiation technology, new irradiation engineering building, high temperature multi-paired thermocouple, experiences of optical measurement, recycling technology on used beryllium reflector are introduced.

  8. Status of Irradiation technology development in JMTR

    Energy Technology Data Exchange (ETDEWEB)

    Inaba, Y.; Inoue, S.; Izumo, H.; Kitagishi, S.; Tsuchiya, K.; Saito, T.; Ishitsuka, E. [Japan Atomic Energy Agency, Ibaraki Ken (Japan)

    2008-11-15

    Irradiation Engineering Section of the Neutron Irradiation and Testing Reactor Center was organized to development the new irradiation technology for the application at JMTR re operation. The new irradiation engineering building was remodeled from the old RI development building, and was started to use from the end of September, 2008. Advanced in situ instrumentation technology (high temperature multi paired thermocouple, ceramic sensor, application of optical measurement), {sup 99M}o production technology by new Mo solution irradiation method, recycling technology on used beryllium reflector, and so on are planned as the development of new irradiation technologies. The development will be also important for the education and training programs through the development of young generation in not only Japan but also Asian counties. In this report, as the status of the development the new irradiation technology, new irradiation engineering building, high temperature multi paired thermocouple, experiences of optical measurement, recycling technology on used beryllium reflector are introduced.

  9. AGR-1 Compact 5-3-1 Post-Irradiation Examination Results

    Energy Technology Data Exchange (ETDEWEB)

    Demkowicz, Paul [Idaho National Lab. (INL), Idaho Falls, ID (United States); Harp, Jason [Idaho National Lab. (INL), Idaho Falls, ID (United States); Winston, Phil [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ploger, Scott A. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-12-01

    The Advanced Gas Reactor (AGR) Fuel Development and Qualification Program was established to perform the requisite research and development on tristructural isotropic (TRISO) coated particle fuel to support deployment of a high-temperature gas-cooled reactor (HTGR). The work continues as part of the Advanced Reactor Technologies (ART) TRISO Fuel program. The overarching program goal is to provide a baseline fuel qualification data set to support licensing and operation of an HTGR. To achieve these goals, the program includes the elements of fuel fabrication, irradiation, post-irradiation examination (PIE) and safety testing, fuel performance, and fission product transport (INL 2015). A series of fuel irradiation experiments is being planned and conducted in the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL). These experiments will provide data on fuel performance under irradiation, support fuel process development, qualify the fuel for normal operating conditions, provide irradiated fuel for safety testing, and support the development of fuel performance and fission product transport models. The first of these irradiation tests, designated AGR-1, began in the ATR in December 2006 and ended in November 2009. This experiment was conducted primarily to act as a shakedown test of the multicapsule test train design and provide early data on fuel performance for use in fuel fabrication process development. It also provided samples for post-irradiation safety testing, where fission product retention of the fuel at high temperatures will be experimentally measured. The capsule design and details of the AGR-1 experiment have been presented previously.

  10. Fuel or irradiation subassembly

    Science.gov (United States)

    Seim, O.S.; Hutter, E.

    1975-12-23

    A subassembly for use in a nuclear reactor is described which incorporates a loose bundle of fuel or irradiation pins enclosed within an inner tube which in turn is enclosed within an outer coolant tube and includes a locking comb consisting of a head extending through one side of the inner sleeve and a plurality of teeth which extend through the other side of the inner sleeve while engaging annular undercut portions in the bottom portion of the fuel or irradiation pins to prevent movement of the pins.

  11. AGR-2 Irradiation Test Final As-Run Report

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States). VHTR Program

    2014-08-01

    This document presents the as-run analysis of the AGR-2 irradiation experiment. AGR-2 is the second of the planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the U.S. Department of Energy as part of the Very High Temperature Reactor (VHTR) Technical Development Office (TDO) program. The objectives of the AGR-2 experiment are to: (a) Irradiate UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Fuel attributes are based on results obtained from the AGR-1 test and other project activities. (b) Provide irradiated fuel samples for post-irradiation experiment (PIE) and safety testing. (c) Support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. The primary objective of the test was to irradiate both UCO and UO2 TRISO (tri-structural isotropic) fuel produced from prototypic scale equipment to obtain normal operation and accident condition fuel performance data. The UCO compacts were subjected to a range of burnups and temperatures typical of anticipated prismatic reactor service conditions in three capsules. The test train also includes compacts containing UO2 particles produced independently by the United States, South Africa, and France in three separate capsules. The range of burnups and temperatures in these capsules were typical of anticipated pebble bed reactor service conditions. The results discussed in this report pertain only to U.S. produced fuel.

  12. AGR-2 Irradiation Test Final As-Run Report

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States). VHTR Program

    2014-08-01

    This document presents the as-run analysis of the AGR-2 irradiation experiment. AGR-2 is the second of the planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the U.S. Department of Energy as part of the Very High Temperature Reactor (VHTR) Technology Development Office (TDO) program. The objectives of the AGR-2 experiment are to: 1. Irradiate UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Fuel attributes are based on results obtained from the AGR-1 test and other project activities. 2. Provide irradiated fuel samples for post-irradiation experiment (PIE) and safety testing. 3. Support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. The primary objective of the test was to irradiate both UCO and UO2 TRISO (tristructural isotropic) fuel produced from prototypic scale equipment to obtain normal operation and accident condition fuel performance data. The UCO compacts were subjected to a range of burnups and temperatures typical of anticipated prismatic reactor service conditions in three capsules. The test train also includes compacts containing UO2 particles produced independently by the United States, South Africa, and France in three separate capsules. The range of burnups and temperatures in these capsules were typical of anticipated pebble bed reactor service conditions. The results discussed in this report pertain only to U.S.-produced fuel.

  13. The Role of Counseling in an Associate Degree in Labor Studies Program: Counseling in a Work Oriented Setting (The Importance of Including Counseling Courses within the Curriculum of the Associate Degree in Labor Studies Program at the Community College Level).

    Science.gov (United States)

    Kingery, Bruce

    This research had a two-fold purpose: (1) to assess the need for a labor studies program at the community college level; and (2) to consider the advisability of including within such a curriculum a cross-section of adult/family/worker-oriented counseling and guidance courses. The study employed a questionnaire completed by union delegates, which…

  14. Evaluation of a multi-faceted diabetes care program including community-based peer educators in Takeo province, Cambodia, 2007-2013.

    Directory of Open Access Journals (Sweden)

    Dawn Taniguchi

    Full Text Available Early detection and treatment for diabetes are essential for reducing disability and death from the disease. Finding effective screening and treatment for individuals living with diabetes in resource-limited countries is a challenge. MoPoTsyo, a Cambodian non-governmental organization, addressed this gap by utilizing a multi-pronged approach with community-based peer educators, access to laboratory procedures, local outpatient medical consultation, and a revolving drug fund. This study evaluated outcomes of MoPoTsyo's diabetes program in Takeo Province by assessing glycemic and blood pressure outcomes for individuals diagnosed with diabetes over a 24-month follow-up period between 2007-2013.This is a retrospective cohort analysis of records without a comparison group. We calculated the mean fasting blood glucose (FBG and blood pressure (BP at regular intervals of follow-up. The proportion of patients reaching recommended treatment targets for FBG and BP was assessed.Of the 3411 patients enrolled in the program, 2230 were included in the study. The cohort was predominantly female (68.9% with a median age of 54 years. Median follow-up time in the program was 16 months (4.9-38.4 months. Mean FBG decreased 63.9 mg/dl in mean FBG (95% CI 58.5 to 69.3 at one year of follow-up (p<0.001. After one year, 45% (321/708 of patients achieved goal FBG < 126. Of the 41.6% (927/2230 with elevated BP at enrollment, systolic and diastolic BP levels significantly decreased (p<0.001 by 16.9 mmHg (95% CI 1.2 to 22.9 and 10 mm Hg (95% CI 0.7 to 12.9 respectively between enrollment and one year of follow-up. At one year of follow-up, 51.1%% (183/355 of these patients reached the BP goal < 140/90.The improved outcome indicators of diabetes care for MoPoTsyo's Takeo program evaluation showed promise. The program demonstrated a reasonable and practical approach to delivering effective diabetes care in a rural area and may serve as a model for other low-income communities

  15. Evaluation of a multi-faceted diabetes care program including community-based peer educators in Takeo province, Cambodia, 2007-2013.

    Science.gov (United States)

    Taniguchi, Dawn; LoGerfo, James; van Pelt, Maurits; Mielcarek, Bessie; Huster, Karin; Haider, Mahri; Thomas, Bernadette

    2017-01-01

    Early detection and treatment for diabetes are essential for reducing disability and death from the disease. Finding effective screening and treatment for individuals living with diabetes in resource-limited countries is a challenge. MoPoTsyo, a Cambodian non-governmental organization, addressed this gap by utilizing a multi-pronged approach with community-based peer educators, access to laboratory procedures, local outpatient medical consultation, and a revolving drug fund. This study evaluated outcomes of MoPoTsyo's diabetes program in Takeo Province by assessing glycemic and blood pressure outcomes for individuals diagnosed with diabetes over a 24-month follow-up period between 2007-2013. This is a retrospective cohort analysis of records without a comparison group. We calculated the mean fasting blood glucose (FBG) and blood pressure (BP) at regular intervals of follow-up. The proportion of patients reaching recommended treatment targets for FBG and BP was assessed. Of the 3411 patients enrolled in the program, 2230 were included in the study. The cohort was predominantly female (68.9%) with a median age of 54 years. Median follow-up time in the program was 16 months (4.9-38.4 months). Mean FBG decreased 63.9 mg/dl in mean FBG (95% CI 58.5 to 69.3) at one year of follow-up (p<0.001). After one year, 45% (321/708) of patients achieved goal FBG < 126. Of the 41.6% (927/2230) with elevated BP at enrollment, systolic and diastolic BP levels significantly decreased (p<0.001) by 16.9 mmHg (95% CI 1.2 to 22.9) and 10 mm Hg (95% CI 0.7 to 12.9) respectively between enrollment and one year of follow-up. At one year of follow-up, 51.1%% (183/355) of these patients reached the BP goal < 140/90. The improved outcome indicators of diabetes care for MoPoTsyo's Takeo program evaluation showed promise. The program demonstrated a reasonable and practical approach to delivering effective diabetes care in a rural area and may serve as a model for other low-income communities

  16. Limites e possibilidades dos programas de aceleração de aprendizagem The limits and possibilities of including students from remedial learning programs in regular schooling

    Directory of Open Access Journals (Sweden)

    Clarilza Prado de Sousa

    1999-11-01

    Full Text Available Pretendi neste trabalho analisar os limites e possibilidades da escola integrar alunos com atraso de escolaridade em processos de educação regular, que receberam apoio de programas de aceleração da aprendizagem. Baseada nas avaliações realizadas desses programas por professores do Programa de Estudos Pós-Graduados em Psicologia da Educação da PUCSP e por pesquisadores do Núcleo de Avaliação Educacional da Fundação Carlos Chagas, discuto os resultados efetivamente alcançados considerando duas categorias de análise. Na primeira categoria, analiso os efeitos da estratégia pedagógica promovida pelos programas, nas aprendizagens e progressos dos alunos participantes. Na segunda categoria, procuro analisar as possibilidades de integração/inclusão desses alunos no processo de educação regular. Finalmente, à guisa de conclusão, procuro fazer algumas considerações teórico-metodológicas. Distinguindo integração de inclusão, discuto os limites e possibilidades que as ações dos programas têm de realmente promoverem o desenvolvimento de uma escola sem exclusão.This article analyzes the limits and possibilities for schools to include students with schooling deficits who receive support from the accelerated learning programs, in their regular education processes. Based on evaluations of these programs done by professors from the Post Graduate Program in Educational Psychology of the Pontifical Catholic University of São Paulo and by researchers from the Nucleus for Educational Evaluation of the Carlos Chagas Foundation, the results will be discussed in two analytical categories. In the first category, I analyze the effects of the teaching strategies promoted by the programs on the learning and progress of the participating students. In the second category, I seek to analyze the possibilities for integration/inclusion of these students in the regular educational process. Finally by way of conclusion, I try to make some

  17. Enhancing utilization of cowpeas through gamma irradiation ...

    African Journals Online (AJOL)

    Several techniques including the use of gamma irradiation are available to Food Scientists in this respect. Gamma irradiation has the potential to modify the functional properties of cowpeas mainly through its effects on inherent protein and starch components. The effects of γ-irradiation on the functional properties of cowpea ...

  18. Benefits of a 12-week lifestyle modification program including diet and combined aerobic and resistance exercise on albuminuria in diabetic and non-diabetic Japanese populations.

    Science.gov (United States)

    Yamamoto-Kabasawa, Keiko; Hosojima, Michihiro; Yata, Yusuke; Saito, Mariko; Tanaka, Noriko; Tanaka, Junta; Tanabe, Naohito; Narita, Ichiei; Arakawa, Masaaki; Saito, Akihiko

    2015-12-01

    Albuminuria is a biomarker for chronic kidney disease and an independent predictor of cardiovascular and all-cause mortality. A recent meta-analysis concluded that these risks increase with urinary albumin concentration, even when below the microalbuminuria threshold. Thus, minimizing urinary albumin may be a valuable therapeutic goal regardless of disease status. We investigated the benefits and safety of a 12-week lifestyle modification program including diet and combined aerobic and resistance exercise for reducing albuminuria in 295 normoalbuminuric or microalbuminuric Japanese adults, including 30 with type 2 diabetes mellitus (T2DM), 104 with metabolic syndrome (MS), and 145 with hypertension (HT). In the study population, the urinary albumin:creatinine ratio (UACR) was reduced significantly (ΔUACR -3.8 ± 16.8 mg/g, P < 0.001) with no change in estimated glomerular filtration rate (eGFR) (ΔeGFR -0.4 ± 7.4 mL/min/1.73 m(2), P = 0.343). The reduction in UACR was associated with decreased fasting plasma glucose (P < 0.05). The UACR was also reduced in the T2DM, MS, and HT groups with no change in eGFR. Reduced UACR was associated with decreased fasting plasma glucose in the MS group and decreased systolic blood pressure in the HT group. The UACR was also reduced in 46 subjects using renin-angiotensin system inhibitors with no change in eGFR. Our 12-week lifestyle modification program reduced UACR, maintained eGFR, and improved multiple fitness findings in Japanese subjects including T2DM, MS, and HT patients.

  19. FAR EAST TECHNICAL ASSISTANCE PROGRAMS OF U.S. NON-PROFIT ORGANIZATIONS (INCLUDING VOLUNTARY AGENCIES, MISSIONS, AND FOUNDATIONS), DIRECTORY - 1966.

    Science.gov (United States)

    BURGESS, MARY ELLEN, ED.

    PART 1 OF THIS PROGRAM GUIDE LISTS TECHNICAL ASSISTANCE AGENCIES AND OTHER ORGANIZATIONS FOR THE FAR EAST, TOGETHER WITH ADDRESSES, TELEPHONE NUMBERS, EXECUTIVE OFFICERS, PROGRAM DIRECTORS, COUNTRIES SERVED, AND ESTIMATED COSTS. PART 2 GIVES PROGRAM DATA (ORGANIZATIONS, OPERATING AND SUPPORT PROGRAMS, TYPES OF ASSISTANCE, REGIONAL REPRESENTATIVES,…

  20. Transiting Exoplanet Survey Satellite (TESS) Community Observer Program including the Science Enhancement Option Box (SEO Box) - 12 TB On-board Flash Memory for Serendipitous Science

    Science.gov (United States)

    Schingler, Robert; Villasenor, J. N.; Ricker, G. R.; Latham, D. W.; Vanderspek, R. K.; Ennico, K. A.; Lewis, B. S.; Bakos, G.; Brown, T. M.; Burgasser, A. J.; Charbonneau, D.; Clampin, M.; Deming, L. D.; Doty, J. P.; Dunham, E. W.; Elliot, J. L.; Holman, M. J.; Ida, S.; Jenkins, J. M.; Jernigan, J. G.; Kawai, N.; Laughlin, G. P.; Lissauer, J. J.; Martel, F.; Sasselov, D. D.; Seager, S.; Torres, G.; Udry, S.; Winn, J. N.; Worden, S. P.

    2010-01-01

    The Transiting Exoplanet Survey Satellite (TESS) will perform an all-sky survey in a low-inclination, low-Earth orbit. TESS's 144 GB of raw data collected each orbit will be stacked, cleaned, cut, compressed and downloaded. The Community Observer Program is a Science Enhancement Option (SEO) that takes advantage of the low-radiation environment, technology advances in flash memory, and the vast amount of astronomical data collected by TESS. The Community Observer Program requires the addition of a 12 TB "SEO Box” inside the TESS Bus. The hardware can be built using low-cost Commercial Off-The-Shelf (COTS) components and fits within TESS's margins while accommodating GSFC gold rules. The SEO Box collects and stores a duplicate of the TESS camera data at a "raw” stage ( 4.3 GB/orbit, after stacking and cleaning) and makes them available for on-board processing. The sheer amount of onboard storage provided by the SEO Box allows the stacking and storing of several months of data, allowing the investigator to probe deeper in time prior to a given event. Additionally, with computation power and data in standard formats, investigators can utilize data-mining techniques to investigate serendipitous phenomenon, including pulsating stars, eclipsing binaries, supernovae or other transient phenomena. The Community Observer Program enables ad-hoc teams of citizen scientists to propose, test, refine and rank algorithms for on-board analysis to support serendipitous science. Combining "best practices” of online collaboration, with careful moderation and community management, enables this `crowd sourced’ participatory exploration with a minimal risk and impact on the core TESS Team. This system provides a powerful and independent tool opening a wide range of opportunity for science enhancement and secondary science. Support for this work has been provided by NASA, the Kavli Foundation, Google, and the Smithsonian Institution.

  1. [Effects of a smoking cessation program including telephone counseling and text messaging using stages of change for outpatients after a myocardial infarction].

    Science.gov (United States)

    Kong, Jung-Hyeon; Ha, Yeongmi

    2013-08-01

    This study was done to identify effects of a smoking cessation program including telephone counseling and text messaging using stages of change for outpatients who have had a myocardial infarction (MI). This research was a quasi-experimental design with a nonequivalent control group pretest-posttest. The participants were 48 outpatients (experimental group=24, control group=24) recruited from one university hospital. They were randomly assigned to one of two groups: (a) an experimental group with telephone counseling (once a week) and text messaging (five times a week) using stages of change, and (b) a control group with traditional telephone counseling (once a month). Efficacy of the intervention was measured by comparing the two groups on smoking-related variables at 3 weeks and 12 weeks. At the 3-week and 12-week measurements, there were significant differences between the experimental and control groups on smoking cessation self-efficacy (pstages of change is effective for outpatients after a MI. Further attention should be paid to the intensity of the smoking cessation program and periods for long-term follow-up.

  2. Is expanding HPV vaccination programs to include school-aged boys likely to be value-for-money: a cost-utility analysis in a country with an existing school-girl program.

    Science.gov (United States)

    Pearson, Amber L; Kvizhinadze, Giorgi; Wilson, Nick; Smith, Megan; Canfell, Karen; Blakely, Tony

    2014-06-26

    Similar to many developed countries, vaccination against human papillomavirus (HPV) is provided only to girls in New Zealand and coverage is relatively low (47% in school-aged girls for dose 3). Some jurisdictions have already extended HPV vaccination to school-aged boys. Thus, exploration of the cost-utility of adding boys' vaccination is relevant. We modeled the incremental health gain and costs for extending the current girls-only program to boys, intensifying the current girls-only program to achieve 73% coverage, and extension of the intensive program to boys. A Markov macro-simulation model, which accounted for herd immunity, was developed for an annual cohort of 12-year-olds in 2011 and included the future health states of: cervical cancer, pre-cancer (CIN I to III), genital warts, and three other HPV-related cancers. In each state, health sector costs, including additional health costs from extra life, and quality-adjusted life-years (QALYs) were accumulated. The model included New Zealand data on cancer incidence and survival, and other cause mortality (all by sex, age, ethnicity and deprivation). At an assumed local willingness-to-pay threshold of US$29,600, vaccination of 12-year-old boys to achieve the current coverage for girls would not be cost-effective, at US$61,400/QALY gained (95% UI $29,700 to $112,000; OECD purchasing power parities) compared to the current girls-only program, with an assumed vaccine cost of US$59 (NZ$113). This was dominated though by the intensified girls-only program; US$17,400/QALY gained (95% UI: dominant to $46,100). Adding boys to this intensified program was also not cost-effective; US$128,000/QALY gained, 95% UI: $61,900 to $247,000).Vaccination of boys was not found to be cost-effective, even for additional scenarios with very low vaccine or program administration costs - only when combined vaccine and administration costs were NZ$125 or lower per dose was vaccination of boys cost-effective. These results suggest that

  3. Exploratory Study of Irradiation, Annealing, and Reirradiation Effects on American and Russian Reactor Pressure Vessel Steels

    Energy Technology Data Exchange (ETDEWEB)

    Chernobaeva, A.A., Kryukov, A.M., Nikolaev, Y.A., Korolev, Y.N. [Russian Research Centre Kurchatov Inst., Moscow (Russian Federation)], Sokolov, M.A., Nanstad, R.K. [Oak Ridge National Lab., TN (United States)

    1997-12-31

    One of the options to mitigate the effects of irradiation on reactor pressure vessels (RPVS) is to thermally anneal them to restore the toughness properties that have been degraded by neutron irradiation. even though a postirradiation anneal may be deemed successful, a critical aspect of continued RPV operation is the rate of embrittlement upon reirradiation. There are insufficient data available to allow for verification models of reirradiation embrittlement or for the development of a reliable predictive methodology. This is especially true in the case of fracture toughness data. Under the U.S.-Russia Joint Coordinating Committee for Civilian Nuclear Reactor Safety (JCCCNRS), Working Group 3 on Radiation Embrittlement, Structural Integrity, and Life Extension of Reactor Vessels and Supports agreed to conduct a comparative study of annealing and reirradiation effects on RPV steels. The working group agreed that each side would irradiate, anneal, reirradiate (if feasible), and test two materials of the other; so far, only charpy impact and tensile specimens have been included. Oak Ridge National Laboratory (ornl) conducted such a program (irradiation and annealing) with two weld metals representative of VVER-440 AND VVER-1000 RPVS, while the Russian Research Center-Kurchatov Institute (RRC-KI) conducted a program (irradiation,annealing, reirradiation, and reannealing) with Heavy-Section Steel Technology (HSST) program plate 02 and Heavy-Section Steel Irradiation (HSSI) program weld 73w. The results for each material from each laboratory are compared with those from the other laboratory. the ORNL experiments with the VVER welds included irradiation to about 1 x 10 (exp 19) N/SQ CM ({gt}1 MeV), while the RRC-KI experiments with the U.S. materials included irradiations from about 2 to 18 X 10 (exp 19) N/SQ CM ({gt}1 MeV).

  4. Nutritional status and feeding-tube placement in patients with locally advanced hypopharyngeal cancer included in an induction chemotherapy-based larynx preservation program.

    Science.gov (United States)

    Bozec, Alexandre; Benezery, Karen; Chamorey, Emmanuel; Ettaiche, Marc; Vandersteen, Clair; Dassonville, Olivier; Poissonnet, Gilles; Riss, Jean-Christophe; Hannoun-Lévi, Jean-Michel; Chand, Marie-Eve; Leysalle, Axel; Saada, Esma; Sudaka, Anne; Haudebourg, Juliette; Hebert, Christophe; Falewee, Marie-Noelle; Demard, François; Santini, José; Peyrade, Frédéric

    2016-09-01

    The objective of the study is to evaluate the nutritional status and determine its impact on clinical outcomes in patients with locally advanced hypopharyngeal cancer included in an induction chemotherapy (ICT)-based larynx preservation program without prophylactic feeding-tube placement. All patients with locally advanced (T3/4, N0-3, M0) hypopharyngeal squamous cell carcinoma, technically suitable for total pharyngolaryngectomy, treated by docetaxel, cisplatin and 5-fluorouracil (TPF)-ICT for larynx preservation at our institution between 2004 and 2013, were included in this retrospective study. Patients' nutritional status was closely monitored. Enteral nutrition was used if and when a patient was unable to sustain per-oral nutrition and hydration. The impact of nutritional status on clinical outcomes was investigated in univariate and multivariate analysis. A total of 53 patients (42 men and 11 women, mean age = 58.6 ± 8.2 years) were included in this study. Six (11.3 %) patients had lost more than 10 % of their usual body weight before therapy. Compared with patients' usual weight, the mean maximum patient weight loss during therapeutic management was 8.7 ± 4.5 kg. Enteral nutrition was required in 17 patients (32 %). We found no influence of the tested nutritional status-related factors on response to ICT, toxicity of ICT, overall, cause-specific and recurrence-free survival, and on post-therapeutic swallowing outcome. Maximum weight loss was significantly associated with a higher risk of enteral tube feeding during therapy (p = 0.03) and of complications (grade ≥3, p = 0.006) during RT. Without prophylactic feeding-tube placement, approximately one-third of the patients required enteral nutrition. There was no significant impact of nutritional status on oncologic or functional outcomes.

  5. Dental management of patients irradiated for oral cancer. [Gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Regezi, J.A.; Courtney, R.M.; Kerr, D.A.

    1976-08-01

    Management of patients irradiated for oral cancer should include consideration of their oral health prior to, and after, radiation therapy. Data from 130 patients, followed for a period of 1 to 10 years, are presented and evaluated. The philosophy of retention and maintenance of as many teeth as possible is supported by this data. Extraction of teeth with severe periodontal disease after irradiation also proves to be a relatively safe operation. Osteoradionecrosis tends to be limited in extent and is generally well tolerated by the patient when treated conservatively. A treatment regimen is presented that significantly reduces the morbidity from therapeutic irradiation of the jaws. A comprehensive dental evaluation and follow-up plan coupled with patient cooperation are instrumental to the success of this program.

  6. AFIP-4 Irradiation Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Danielle M Perez; Misti A Lillo; Gray S. Chang; Glenn A Roth; Nicolas Woolstenhulme; Daniel M Wachs

    2011-09-01

    The Advanced Test Reactor (ATR) Full size plate In center flux trap Position (AFIP) experiment AFIP-4 was designed to evaluate the performance of monolithic uranium-molybdenum (U-Mo) fuels at a scale prototypic of research reactor fuel plates. The AFIP-4 test further examine the fuel/clad interface and its behavior under extreme conditions. After irradiation, fission gas retention measurements will be performed during post irradiation (PIE). The following report summarizes the life of the AFIP-4 experiment through end of irradiation, including a brief description of the safety analysis, as-run neutronic analysis results, hydraulic testing results, and thermal analysis results.

  7. AFIP-4 Irradiation Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Danielle M Perez; Misti A Lillo; Gray S. Chang; Glenn A Roth; Nicolas Woolstenhulme; Daniel M Wachs

    2012-01-01

    The Advanced Test Reactor (ATR) Full size plate In center flux trap Position (AFIP) experiment AFIP-4 was designed to evaluate the performance of monolithic uranium-molybdenum (U-Mo) fuels at a scale prototypic of research reactor fuel plates. The AFIP-4 test further examine the fuel/clad interface and its behavior under extreme conditions. After irradiation, fission gas retention measurements will be performed during post irradiation (PIE)1,2. The following report summarizes the life of the AFIP-4 experiment through end of irradiation, including a brief description of the safety analysis, as-run neutronic analysis results, hydraulic testing results, and thermal analysis results.

  8. Development of a 2-h suicide prevention program for medical staff including nurses and medical residents: A two-center pilot trial.

    Science.gov (United States)

    Nakagami, Yukako; Kubo, Hiroaki; Katsuki, Ryoko; Sakai, Tomomichi; Sugihara, Genichi; Naito, Chisako; Oda, Hiroyuki; Hayakawa, Kohei; Suzuki, Yuriko; Fujisawa, Daisuke; Hashimoto, Naoki; Kobara, Keiji; Cho, Tetsuji; Kuga, Hironori; Takao, Kiyoshi; Kawahara, Yoko; Matsumura, Yumi; Murai, Toshiya; Akashi, Koichi; Kanba, Shigenobu; Otsuka, Kotaro; Kato, Takahiro A

    2018-01-01

    Suicide is a crucial global health concern and effective suicide prevention has long been warranted. Mental illness, especially depression is the highest risk factor of suicide. Suicidal risk is increased in people not only with mental illness but also with physical illnesses, thus medical staff caring for physically-ill patients are also required to manage people with suicidal risk. In the present study, we evaluated our newly developed suicide intervention program among medical staff. We developed a 2-h suicide intervention program for medical staff, based on the Mental Health First Aid (MHFA), which had originally been developed for the general population. We conducted this program for 74 medical staff members from 2 hospitals. Changes in knowledge, perceived skills, and confidence in early intervention of depression and suicide-prevention were evaluated using self-reported questionnaires at 3 points; pre-program, immediately after the program, and 1 month after program. This suicide prevention program had significant effects on improving perceived skills and confidence especially among nurses and medical residents. These significant effects lasted even 1 month after the program. Design was a single-arm study with relatively small sample size and short-term follow up. The present study suggests that the major target of this effective program is nurses and medical residents. Future research is required to validate the effects of the program with control groups, and also to assess long-term effectiveness and actual reduction in suicide rates. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Future Satellite Observations of Solar Irradiance

    Science.gov (United States)

    Cahalan, R. F.; Rottman, G.; Woods, T.; Lawrence, G.; Harder, J.; McClintock, W.; Kopp, G.

    2003-01-01

    Required solar irradiance measurements for climate studies include those now being made by the Total Irradiance Monitor (TIM) and the Spectral Irradiance Monitor (SIM) onboard the SORCE satellite, part of the Earth Observing System fleet of NASA satellites. Equivalent or better measures of Total Solar Irradiance (TSI) and Spectral Solar Irradiance (SSI, 200 to 2000 nm) are planned for the post-2010 satellites of the National Polar-orbiting Operational Environmental Satellite System ("OESS). The design life of SORCE is 5 years, so a "Solar Irradiance Gap Filler" EOS mission is being planned for launch in the 2007 time frame, to include the same TSI and SSI measurements. Besides avoiding any gap, overlap of the data sources is also necessary for determination of possible multi-decadal trends in solar irradiance. We discuss these requirements and the impacts of data gaps, and data overlaps, that may occur in the monitoring of the critical solar radiative forcing.

  10. Medium term effects of including manual therapy in a pulmonary rehabilitation program for chronic obstructive pulmonary disease (COPD): a randomized controlled pilot trial.

    Science.gov (United States)

    Engel, Roger Mark; Gonski, Peter; Beath, Ken; Vemulpad, Subramanyam

    2016-05-01

    Randomized clinical trial. To investigate the effect of including manual therapy (MT) in a pulmonary rehabilitation program for patients with chronic obstructive pulmonary disease (COPD). The primary source of exercise limitation in people with COPD is dyspnea. The dyspnea is partly caused by changes in chest wall mechanics, with an increase in chest wall rigidity (CWR) contributing to a decrease in lung function. As MT is known to increase joint mobility, administering MT to people with COPD carries with it the potential to influence CWR and lung function. Thirty-three participants with COPD, aged between 55 and 70 years (mean = 65·5±4 years), were randomly assigned to three groups: pulmonary rehabilitation (PR) only, soft tissue therapy (ST) and PR, and ST, spinal manipulative therapy (SM), and PR. Outcome measures including forced expiratory volume in the 1st second (FEV1), forced vital capacity (FVC), 6-minute walking test (6MWT), St. George's respiratory questionnaire (SGRQ), and the hospital anxiety and depression (HAD) scale were recorded at 0, 8, 16, and 24 weeks. There was a significant difference in FVC between the three groups at 24 weeks (P = 0·04). For the ST+SM+PR group versus PR only the increase was 0·40 l (CI: 0·02, 0·79; P = 0·03). No major or moderate adverse events (AE) were reported following the administration of 131 ST and 272 SM interventions. The increase in FVC is a unique finding. Although the underlying mechanisms responsible for this outcome are not yet understood, the most likely explanation is the synergistic effect resulting from the combination of interventions. These results support the call for a larger clinical trial in the use of MT for COPD.

  11. Radiation-disorder and aperiodicity in irradiated ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Hobbs, L.W.

    1992-01-01

    This final technical report documents the accomplishments of the program of research entitled Radiation Disorder and Aperiodicity in Irradiated Ceramics'' for the period June 22, 1989--June 21, 1992. This research forms the latest part on an on-going program, begun at MIT in 1983 under DOE support, which has had as its objectives investigation of the responses in radiation environments of ceramics heavily-irradiated with electrons, neutrons and ions, with potential applications to fusion energy technology and high-level nuclear waste storage. Materials investigated have included SiO{sub 2}, MgAl{sub 2}O{sub 4}, Al{sub 23}O{sub 27}N{sub 5}, SiC, BeO, LiAlO{sub 2}, Li{sub 2}ZrO{sub 3}, CaTiO{sub 3}KTaO{sub 3} and Ca(Zr, Pu)Ti{sub 2}O{sub 7}. The program initially proposed for 1989 had as its major objectives two main thrusts: (1) research on defect aggregation in irradiated non-oxide ceramics, and (2) research on irradiation-induced amorphization of network silicas and phosphates.

  12. Nuclear Energy Research Initiative Program (NERI) Quarterly Progress Report; New Design Equations for Swelling and Irradiation Creep in Generation IV Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Wolfer, W G; Surh, M P; Garner, F A; Chrzan, D C; Schaldach, C; Sturgeon, J B

    2003-02-13

    The objectives of this research project are to significantly extend the theoretical foundation and the modeling of radiation-induced microstructural changes in structural materials used in Generation IV nuclear reactors, and to derive from these microstructure models the constitutive laws for void swelling, irradiation creep and stress-induced swelling, as well as changes in mechanical properties. The need for the proposed research is based on three major developments and advances over the past two decades. First, new experimental discoveries have been made on void swelling and irradiation creep which invalidate previous theoretical models and empirical constitutive laws for swelling and irradiation creep. Second, recent advances in computational methods and power make it now possible to model the complex processes of microstructure evolution over long-term neutron exposures. Third, it is now required that radiation-induced changes in structural materials over extended lifetimes be predicted and incorporated in the design of Generation IV reactors. Our approach to modeling and data analysis is a dual one in accord with both the objectives to simulate the evolution of the microstructure and to develop design equations for macroscopic properties. Validation of the models through data analysis is therefore carried out at both the microscopic and the macroscopic levels. For the microstructure models, we utilize the transmission electron microscopy results from steels irradiated in reactors and from model materials irradiated by neutrons as well as ion bombardments. The macroscopic constitutive laws will be tested and validated by analyzing density data, irradiation creep data, diameter changes of fuel elements, and post-irradiation tensile data. Validation of both microstructure models and macroscopic constitutive laws is a more stringent test of the internal consistency of the underlying science for radiation effects in structural materials for nuclear reactors.

  13. Schedule and status of irradiation experiments

    Energy Technology Data Exchange (ETDEWEB)

    Rowcliffe, A.F.; Grossbeck, M.L.; Robertson, J.P. [Oak Ridge National Lab., TN (United States)

    1998-09-01

    The current status of reactor irradiation experiments is presented in tables summarizing the experimental objectives, conditions, and schedule. Currently, the program has one irradiation experiment in reactor and five experiments in the design or construction stages. Postirradiation examination and testing is in progress on ten experiments.

  14. THE INFLUENCE OF COMBINATION NON-MEDICAL TREATMENT INCLUDING FUNCTIONAL PROGRAMMED ELECTRICAL STIMULATION ON THE CLINICAL AND INSTRUMENTAL PARAMETERS IN PATIENTS WITH CEREBRAL PALSY WITH SPASTIC DIPLEGIA

    Directory of Open Access Journals (Sweden)

    V. V. Eliseev

    2015-01-01

    Full Text Available Background: Cerebral palsy is the leading cause of physical disability in pediatric  age. The search for new methods and improvement of old rehabil- itation techniques is ongoing, due to low efficacy of the latter. Aim: To assess the efficacy of a func- tional programmed electrical muscle stimulation as a part  of combination treatment of patients with cerebral palsy in the form of spastic diplegia. Materials and methods: We analyzed the results of treatment of 71 children with cerebral palsy and spastic diplegia, who had  been  randomized  into two groups  depending on the type of treatment. In  the  first group,  the  patients  (n = 38 received a course of functional programmed electric stim- ulation  in combination with  other  non-medical treatment  methods.  The  second   group   (n = 33 underwent a usual  course  of electrical  stimula- tion in combination with non-medical  treatment, similar to that  in the first group. The third group (control   included   41   children   without    cere- bral palsy. Clinical and  instrumental parameters were  assessed  in all study  participants. Results: After the course of combination treatment in the group  1, the  tonus  of m. gastrocnemius was de- creased significantly by 41%, that of the posterior group  of femur muscles by 43%, adductor group of femur muscles by 36%. In the group  2, the re- spective parameters decreased by 24, 21 and 21%. Muscle power  endurance was  increased  signifi- cantly in patients of both groups: that of long back extensors by 12.5 and 6.2 sec, of m. rectus abdomi- nis by 10.6 sec and 5.2 sec, of gluteal muscles by 9.3 and 4.6 sec, of m. quadriceps  by 19.8 and 7.2 sec, of m. anterior  tibialis by 12.1 and 4.6 sec, respec- tively. After the  treatment, the  active movement volume in the large joints of lower extremities  in the group 1 patients  improved as follows: by 15.6° in hip joints, by 11.1° in knee joints and by

  15. PRELIMINARY RESULTS OF THE AGC-4 IRRADIATION IN THE ADVANCED TEST REACTOR AND DESIGN OF AGC-5 (HTR16-18469)

    Energy Technology Data Exchange (ETDEWEB)

    Davenport, Michael; Petti, D. A.

    2016-11-01

    The United States Department of Energy’s Advanced Reactor Technologies (ART) Program will irradiate up to six nuclear graphite creep experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The graphite experiments are being irradiated over an approximate eight year period to support development of a graphite irradiation performance data base on the new nuclear grade graphites now available for use in high temperature gas reactors. The goals of the irradiation experiments are to obtain irradiation performance data, including irradiation creep, at different temperatures and loading conditions to support design of the Very High Temperature Gas Reactor (VHTR), as well as other future gas reactors. The experiments each consist of a single capsule that contain six stacks of graphite specimens, with half of the graphite specimens in each stack under a compressive load, while the other half of the specimens are not be subjected to a compressive load during irradiation. The six stacks have differing compressive loads applied to the top half of diametrically opposite pairs of specimen stacks. A seventh specimen stack in the center of the capsule does not have a compressive load. The specimens are being irradiated in an inert sweep gas atmosphere with on-line temperature and compressive load monitoring and control. There are also samples taken of the sweep gas effluent to measure any oxidation or off-gassing of the specimens that may occur during initial start-up of the experiment. The first experiment, AGC-1, started its irradiation in September 2009, and the irradiation was completed in January 2011. The second experiment, AGC-2, started its irradiation in April 2011 and completed its irradiation in May 2012. The third experiment, AGC-3, started its irradiation in late November 2012 and completed in the April of 2014. AGC-4 is currently being irradiated in the ATR. This paper will briefly discuss the preliminary irradiation results

  16. Ceftazidime-avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program.

    Science.gov (United States)

    Wagenlehner, Florian M; Sobel, Jack D; Newell, Paul; Armstrong, Jon; Huang, Xiangning; Stone, Gregory G; Yates, Katrina; Gasink, Leanne B

    2016-09-15

    The global emergence of carbapenem-resistant Enterobacteriaceae highlights the urgent need to reduce carbapenem dependence. The phase 3 RECAPTURE program compared the efficacy and safety of ceftazidime-avibactam and doripenem in patients with complicated urinary tract infection (cUTI), including acute pyelonephritis. Hospitalized adults with suspected or microbiologically confirmed cUTI/acute pyelonephritis were randomized 1:1 to ceftazidime-avibactam 2000 mg/500 mg every 8 hours or doripenem 500 mg every 8 hours (doses adjusted for renal function), with possible oral antibiotic switch after ≥5 days (total treatment duration up to 10 days or 14 days for patients with bacteremia). Of 1033 randomized patients, 393 and 417 treated with ceftazidime-avibactam and doripenem, respectively, were eligible for the primary efficacy analyses; 19.6% had ceftazidime-nonsusceptible baseline pathogens. Noninferiority of ceftazidime-avibactam vs doripenem was demonstrated for the US Food and Drug Administration co-primary endpoints of (1) patient-reported symptomatic resolution at day 5: 276 of 393 (70.2%) vs 276 of 417 (66.2%) patients (difference, 4.0% [95% confidence interval {CI}, -2.39% to 10.42%]); and (2) combined symptomatic resolution/microbiological eradication at test of cure (TOC): 280 of 393 (71.2%) vs 269 of 417 (64.5%) patients (difference, 6.7% [95% CI, .30% to 13.12%]). Microbiological eradication at TOC (European Medicines Agency primary endpoint) occurred in 304 of 393 (77.4%) ceftazidime-avibactam vs 296 of 417 (71.0%) doripenem patients (difference, 6.4% [95% CI, .33% to 12.36%]), demonstrating superiority at the 5% significance level. Both treatments showed similar efficacy against ceftazidime-nonsusceptible pathogens. Ceftazidime-avibactam had a safety profile consistent with that of ceftazidime alone. Ceftazidime-avibactam was highly effective for the empiric treatment of cUTI (including acute pyelonephritis), and may offer an alternative to carbapenems in

  17. Food irradiation: Australian quarantine regulatory attitude toward food exports

    Science.gov (United States)

    Luckman, Gary James

    2000-03-01

    The Australian Quarantine and Inspection Service (AQIS) is a major operational unit within the Federal Department of Agriculture, Fisheries and Forestry of Australia. AQIS has a long history of dealing with irradiation issues, as many imported goods (non food) require disinfestation treatment, for which gamma irradiation is the most cost effective, suitable and efficient means. A ministerial decision was taken in April 1997 which authorised AQIS to oversee a trial of irradiation as a pre-shipment treatment for food to be exported from Australia, with several caveats. Any such treatment would be required to meet importing country requirements, it would be conditional on export certification and would be required to meet certain minimum international requirements established by the Codex Alimentarius. These include minimum and maximum dosage levels and labelling to indicate irradiation treatment has taken place. Strong interest has been generated by the announcement of this trial in a number of food industry segments, who are anxious to participate in the trial program. Further to the anticipated success of the export trial, AQIS is drafting suitable legislation which will allow exports of irradiated foodstuffs from a number of food categories, on an ongoing basis.

  18. Food irradiation: Australian quarantine regulatory attitude toward food exports

    Energy Technology Data Exchange (ETDEWEB)

    Luckman, Gary James

    2000-03-01

    The Australian Quarantine and Inspection Service (AQIS) is a major operational unit within the Federal Department of Agriculture, Fisheries and Forestry of Australia. AQIS has a long history of dealing with irradiation issues, as many imported goods (non food) require disinfestation treatment, for which gamma irradiation is the most cost effective, suitable and efficient means. A ministerial decision was taken in April 1997 which authorised AQIS to oversee a trial of irradiation as a pre-shipment treatment for food to be exported from Australia, with several caveats. Any such treatment would be required to meet importing country requirements, it would be conditional on export certification and would be required to meet certain minimum international requirements established by the Codex Alimentarius. These include minimum and maximum dosage levels and labelling to indicate irradiation treatment has taken place. Strong interest has been generated by the announcement of this trial in a number of food industry segments, who are anxious to participate in the trial program. Further to the anticipated success of the export trial, AQIS is drafting suitable legislation which will allow exports of irradiated foodstuffs from a number of food categories, on an ongoing basis. (author)

  19. National Coral Reef Monitoring Program: Stratified Random Surveys (StRS) of Reef Fish, including Benthic Estimate Data of the Mariana Archipelago in 2014 (NCEI Accession 0157596)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data provided in this data set were collected as part of the NOAA Pacific Islands Fisheries Science Center (PIFSC), Coral Reef Ecosystem Program (CREP) led NCRMP...

  20. Status of the NGNP graphite creep experiments AGC-1 and AGC-2 irradiated in the advanced test reactor

    Energy Technology Data Exchange (ETDEWEB)

    S. Blaine Grover

    2014-05-01

    The United States Department of Energy's Next Generation Nuclear Plant (NGNP) Program will be irradiating six nuclear graphite creep experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The graphite experiments will be irradiated over the next six to eight years to support development of a graphite irradiation performance data base on the new nuclear grade graphites now available for use in high temperature gas reactors. The goals of the irradiation experiments are to obtain irradiation performance data, including irradiation creep, at different temperatures and loading conditions to support design of the next generation nuclear plant (NGNP) very high temperature gas reactor, as well as other future gas reactors. The experiments will each consist of a single capsule that will contain six peripheral stacks of graphite specimens, with half of the graphite specimens in each stack under a compressive load, while the other half of the specimens will not be subjected to a compressive load during irradiation. The six peripheral stacks will have three different compressive loads applied to the top half of three diametrically opposite pairs of specimen stacks, while a seventh stack will not have a compressive load. The specimens will be irradiated in an inert sweep gas atmosphere with on-line temperature and compressive load monitoring and control. There will also be sampling the sweep gas effluent to determine if any oxidation or off-gassing of the specimens occurs during irradiation of the experiment.

  1. Development of data base on food irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Hitoshi; Kume, Tamikazu; Hashimoto, Shoji [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment; Izumi, Fumio

    1995-12-01

    For the exact understanding on food irradiation in Japan, it is important to provide information of food irradiation to consumers, industries and government offices. However, many of information on food irradiation are only restricted in a few experts or institutes relating to this field. For this reason, data base of food irradiation has been completed together with the systems necessary for input the data using computer. In this data base, about 630 data with full reports were inputted in computer in the field of wholesomeness studies, irradiation effects on food, radiation engineering, detection methods of irradiated food and Q and A of food irradiation for easy understanding. Many of these data are inputted by Japanese language. Some English reports on wholesomeness studies are also included which were mainly obtained from international projects of food irradiation. Many of data on food irradiation are responsible in the fields of food science, dietetics, microbiology, radiation biology, molecular biology, medical science, agricultural science, radiation chemistry, radiation engineering and so on. Data base of food irradiation contains many useful data which can apply to many other fields of radiation processing not only on food irradiation but also on sterilization of medical equipments, upgrading of agricultural wastes and others. (author).

  2. Integron, Plasmid and Host Strain Characteristics of Escherichia coli from Humans and Food Included in the Norwegian Antimicrobial Resistance Monitoring Programs.

    Directory of Open Access Journals (Sweden)

    Marianne Sunde

    Full Text Available Antimicrobial resistant Escherichia coli (n=331 isolates from humans with bloodstream infections were investigated for the presence of class 1 and class 2 integrons. The integron cassettes arrays were characterized and the findings were compared with data from similar investigations on resistant E. coli from meat and meat products (n=241 produced during the same time period. All isolates were obtained from the Norwegian monitoring programs for antimicrobial resistance in human pathogens and in the veterinary sector. Methods used included PCR, sequencing, conjugation experiments, plasmid replicon typing and subtyping, pulsed-field-gel-electrophoresis and serotyping. Integrons of class 1 and 2 occurred significantly more frequently among human isolates; 45.4% (95% CI: 39.9-50.9 than among isolates from meat; 18% (95% CI: 13.2 -23.3, (p<0.01, Chi-square test. Identical cassette arrays including dfrA1-aadA1, aadA1, dfrA12-orfF-aadA2, oxa-30-aadA1 (class 1 integrons and dfrA1-sat1-aadA1 (class 2 integrons were detected from both humans and meat. However, the most prevalent cassette array in human isolates, dfrA17-aadA5, did not occur in isolates from meat, suggesting a possible linkage between this class 1 integron and a subpopulation of E. coli adapted to a human host. The drfA1-aadA1 and aadA1 class 1 integrons were found frequently in both human and meat isolates. These isolates were subjected to further studies to investigate similarities with regard to transferability, plasmid and host strain characteristics. We detected incF plasmids with pMLST profile F24:A-:B1 carrying drfA1-aadA1 integrons in isolates from pork and in a more distantly related E. coli strain from a human with septicaemia. Furthermore, we showed that most of the class 1 integrons with aadA1 were located on incF plasmids with pMLST profile F51:A-:B10 in human isolates. The plasmid was present in unrelated as well as closely related host strains, demonstrating that dissemination

  3. Endodontics and the irradiated patient

    Energy Technology Data Exchange (ETDEWEB)

    Cox, F.L.

    1976-11-01

    With increasingly larger numbers of irradiated patients in our population, it seems likely that all dentists will eventually be called upon to manage the difficult problems that these patients present. Of utmost concern should be the patient's home care program and the avoidance of osteroradionecrosis. Endodontics and periodontics are the primary areas for preventing or eliminating the infection that threatens osteoradionecrosis. Endodontic treatment must be accomplished with the utmost care and maximum regard for the fragility of the periapical tissues. Pulpally involved teeth should never be left open in an irradiated patient, and extreme care must be taken with the between-visits seal. If one is called upon for preradiation evaluation, routine removal of all molar as well as other compromised teeth should be considered. Attention should be directed to the literature for further advances in the management of irradiated patients.

  4. Irradiation preservation of seafood: Literature review

    Energy Technology Data Exchange (ETDEWEB)

    Molton, P.M.

    1987-10-01

    The application of gamma-irradiation for extending the shelf life of seafood has been of interest for many years. This report reviews a number of studies on seafood irradiation conducted over the past several years. Topics covered include seafood irradiation techniques and dosages, species applicability and differences, the effects of packaging on seafood preservation, and changes in organoleptic acceptability as a result of irradiation. Particular attention is given to radiation effects (likely and unlikely) of concern to the public. These include the potential for generation of toxic chemical products, botulinum toxin production, and other health concerns. No scientifically defensible evidence of any kind was found for any harmful effect of irradiation of seafoods at the doses being considered (less than 300 krad), and all indications are that irradiation is an acceptable and needed additional tool for seafood preservation. 49 refs., 14 figs., 14 tabs.

  5. [Education reform with the support of the faculty--introduction of a supplementary education program including teacher support and individual guidance].

    Science.gov (United States)

    Wada, Keiji; Yoshimura, Teruki

    2015-01-01

      To deal with declining levels of academic ability and motivation among students (a situation attributable to fewer high school graduates, a greater number of universities, and the diversification of entrance examination methods), one must comprehend the conditions of faculties collectively, and take appropriate measures. Using the results of examinations carried out in each grade as indices, we examined levels of academic ability and established various support programs based on the results. Basic chemistry, biology, and physics courses were designed to help first-year students acquire essential academic skills. For second, third, and fourth-year students, two types of support programs were implemented: supplementary instruction to help students improve their understanding of basic topics in pharmaceutical sciences, and an e-learning system to promote self-study, requiring minimal assistance from teachers. Although educational benefits were observed in many students, the number of learners whose understanding failed to improve as a result of the support programs continued to increase. Consequently, The Support Section for Pharmaceutical Education opened in October 2011 to address these concerns. The support section functions mainly to provide individual assistance to students who lack strong academic abilities, and provides teachers with information useful for educational reform. Here, we describe the educational support provided by our faculty and its effectiveness.

  6. Altering Practices to Include Bimodal-bilingual (ASL-Spoken English) Programming at a Small School for the Deaf in Canada.

    Science.gov (United States)

    Priestley, Karen; Enns, Charlotte; Arbuckle, Shauna

    2018-01-01

    Bimodal-bilingual programs are emerging as one way to meet broader needs and provide expanded language, educational and social-emotional opportunities for students who are deaf and hard of hearing (Marschark, M., Tang, G. & Knoors, H. (Eds). (2014). Bilingualism and bilingual Deaf education. New York, NY: Oxford University Press; Paludneviciene & Harris, R. (2011). Impact of cochlear implants on the deaf community. In Paludneviciene, R. & Leigh, I. (Eds.), Cochlear implants evolving perspectives (pp. 3-19). Washington, DC: Gallaudet University Press). However, there is limited research on students' spoken language development, signed language growth, academic outcomes or the social-emotional factors associated with these programs (Marschark, M., Tang, G. & Knoors, H. (Eds). (2014). Bilingualism and bilingual Deaf education. New York, NY: Oxford University Press; Nussbaum, D & Scott, S. (2011). The cochlear implant education center: Perspectives on effective educational practices. In Paludneviciene, R. & Leigh, I. (Eds.) Cochlear implants evolving perspectives (pp. 175-205). Washington, DC: Gallaudet University Press. The cochlear implant education center: Perspectives on effective educational practices. In Paludnevicience & Leigh (Eds). Cochlear implants evolving perspectives (pp. 175-205). Washington, DC: Gallaudet University Press; Spencer, P. & Marschark, M. (Eds.) (2010). Evidence-based practice in educating deaf and hard-of-hearing students. New York, NY: Oxford University Press). The purpose of this case study was to look at formal and informal student outcomes as well as staff and parent perceptions during the first 3 years of implementing a bimodal-bilingual (ASL and spoken English) program within an ASL milieu at a small school for the deaf. Speech and language assessment results for five students were analyzed over a 3-year period and indicated that the students made significant positive gains in all areas, although results were variable. Staff and parent

  7. Pre-irradiation testing of actively cooled Be-Cu divertor modules

    Energy Technology Data Exchange (ETDEWEB)

    Linke, J.; Duwe, R.; Kuehnlein, W. [Forschungszentrum Juelich GmbH (Germany)] [and others

    1995-09-01

    A set of neutron irradiation tests is prepared on different plasma facing materials (PFM) candidates and miniaturized components for ITER. Beside beryllium the irradiation program which will be performed in the High Flux Reactor (HFR) in Petten, includes different carbon fiber composites (CFQ) and tungsten alloys. The target values for the neutron irradiation will be 0.5 dpa at temperatures of 350{degrees}C and 700{degrees}C, resp.. The post irradiation examination (PIE) will cover a wide range of mechanical tests; in addition the degradation of thermal conductivity will be investigated. To determine the high heat flux (HHF) performance of actively cooled divertor modules, electron beam tests which simulate the expected heat loads during the operation of ITER, are scheduled in the hot cell electron beam facility JUDITH. These tests on a selection of different actively cooled beryllium-copper and CFC-copper divertor modules are performed before and after neutron irradiation; the pre-irradiation testing is an essential part of the program to quantify the zero-fluence high heat flux performance and to detect defects in the modules, in particular in the brazed joints.

  8. Effect of irradiation on the Porphyromonas gingivalis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chang Hee; Kim, Gyu Tae; Choi, Yong Suk; Hwang, Eui Hwan [School of Dentistry, Kyung Hee University, Seoul (Korea, Republic of)

    2008-03-15

    The aim of this study was to observe a direct effect of irradiation on the periodontopathic Porphyromonas gingivalis (P. gingivalis). P. gingivalis 2561 was exposed to irradiation with a single absorbed dose of 10, 20, 30, and 40 Gy. Changes in viability and antibiotic sensitivity, morphology, transcription, and protein profile of the bacterium after irradiation were examined by pour plating method, disc diffusion method, transmission electron microscopy, RT-PCR, and immunoblot, respectively. Viability of irradiated P. gingivalis drastically reduced as irradiation dose was increased. Irradiated P. gingivalis was found to have become more sensitive to antibiotics as radiation dose was increased. With observation under the transmission electron microscope, the number of morphologically abnormal cells was increased with increasing of irradiation dose. In RT-PCR, decrease in the expression of fim A and sod was observed in irradiated P. gingivalis. In immunoblot, change of profile in irradiated P. gingivalis was found in a number of proteins including 43-kDa fimbrillin. These results suggest that irradiation may affect the cell integrity of P. gingivalis, which is manifested by the change in cell morphology and antibiotic sensitivity, affecting viability of the bacterium.

  9. Status of Wrought FeCrAl-UO2 Capsules Irradiated in the Advanced Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Harp, J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Core, G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Linton, K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-07-01

    Candidate cladding materials for accident tolerant fuel applications require extensive testing and validation prior to commercial deployment within the nuclear power industry. One class of cladding materials, FeCrAl alloys, is currently undergoing such effort. Within these activities is a series of irradiation programs within the Advanced Test Reactor. These programs are developed to aid in commercial maturation and understand the fundamental mechanisms controlling the cladding performance during normal operation of a typical light water reactor. Three different irradiation programs are on-going; one designed as a simple proof-of-principle concept, the other to evaluate the susceptibility of FeCrAl to fuel-cladding chemical interaction, and the last to fully simulate the conditions of a pressurized water reactor experimentally. To date, nondestructive post-irradiation examination has been completed on the rodlet deemed FCA-L3 from the simple proof-of-concept irradiation program. Initial results show possible breach of the rodlet under irradiation but further studies are needed to conclusively determine whether breach has occurred and the underlying reasons for such a possible failure. Further work includes characterizing additional rodlets following irradiation.

  10. Saturation behavior of irradiation hardening in F82H irradiated in the HFIR

    Energy Technology Data Exchange (ETDEWEB)

    Hirose, T. [Blanket Engineering Group, Japan Atomic Energy Agency, Naka, Ibaraki (Japan); Shiba, K.; Tanigawa, H.; Ando, M. [Japan Atomic Energy Agency, Tokai-mura, Naga-gun, Ibaraki-ken (Japan); Klueh, R.L. [Oak Ridge National Laboratory, TN (United States); Stoller, R. [ORNL - Oak Ridge National Laboratory, Materials Science and Technology Div., Oak Ridge, AK TN (United States)

    2007-07-01

    Full text of publication follows: Post irradiation tensile tests on reduced activation ferritic/martensitic steel, F82H have been conducted over the past two decades using Japan Materials Testing Reactor (JMTR) of JAEA, and Fast Flux Testing Facility (FFTF) of PNNL and High Flux Isotope Reactor (HFIR) of ORNL, USA, under Japan/US collaboration programs. According to these results, F82H does not demonstrate irradiation hardening above 673 K up to 60 dpa. The current study has been concentrated on hardening behavior at temperature around 573 K. A series of low temperature irradiation experiment has been conducted at the HFIR under the international collaborative research between JAEA/US-DOE. In this collaboration, the irradiation condition is precisely controlled by the well matured capsule designing and instrumentation. This paper summarizes recent results of the irradiation experiments focused on F82H and its modified steels compared with the irradiation properties database on F82H. Post irradiation tensile tests have been conducted on the F82H and its modified steels irradiated at 573 K and the dose level was up to 25 dpa. According to these results, irradiation hardening of F82H is saturated by 9 dpa and the as-irradiated 0.2 % proof stress is less than 1 GPa at ambient temperature. The deterioration of total elongation was also saturated by 9 dpa irradiation. The ductility of some modified steels which showed larger total elongation than that of F82H before irradiation become the same level as that of standard F82H steel after irradiation, even though its magnitude of irradiation hardening is smaller than that of F82H. This suggests that the more ductile steel demonstrates the more ductility loss at this temperature, regardless to the hardening level. The difference in ductility loss behavior between various tensile specimens will be discussed as the ductility could depend on the specimen dimension. (authors)

  11. AGR-1 Compact 1-3-1 Post-Irradiation Examination Results

    Energy Technology Data Exchange (ETDEWEB)

    Demkowicz, Paul Andrew [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-12-01

    The Advanced Gas Reactor (AGR) Fuel Development and Qualification Program was established to perform the requisite research and development on tristructural isotropic (TRISO) coated particle fuel to support deployment of a high-temperature gas-cooled reactor (HTGR). The work continues as part of the Advanced Reactor Technologies (ART) TRISO Fuel program. The overarching program goal is to provide a baseline fuel qualification data set to support licensing and operation of an HTGR. To achieve these goals, the program includes the elements of fuel fabrication, irradiation, post-irradiation examination (PIE) and safety testing, fuel performance modeling, and fission product transport (INL 2015). A series of fuel irradiation experiments is being planned and conducted in the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL). These experiments will provide data on fuel performance under irradiation, support fuel process development, qualify the fuel for normal operating conditions, provide irradiated fuel for safety testing, and support the development of fuel performance and fission product transport models. The first of these irradiation tests, designated AGR-1, began in the ATR in December 2006 and ended in November 2009. This experiment was conducted primarily to act as a shakedown test of the multicapsule test train design and provide early data on fuel performance for use in fuel fabrication process development. It also provided samples for post-irradiation safety testing, where fission product retention of the fuel at high temperatures will be experimentally measured. The capsule design and details of the AGR-1 experiment have been presented previously (Grover, Petti, and Maki 2010, Maki 2009).

  12. [A mental health awareness anti-stigma program including user-trainers has a significant impact on knowledge, beliefs and attitudes of job centre professionals in Paris].

    Science.gov (United States)

    Jouet, E; Moineville, M; Favriel, S; Leriche, P; Greacen, T

    2014-04-01

    Developing programs and actions to fight stigma and discrimination against people living with mental disorders is a priority both internationally and in France. Involving mental health service users in these anti-stigma programs has proved to be a key element for effective programs. The present study evaluates the impact of user-trainers in an anti-stigma campaign with job counselors on their knowledge, beliefs, and desire for social distance with regard to mental illness and the mentally ill. Eighty-nine professionals participated in eight mental health awareness days from December 2008 to June 2009. Each training day was built around two pedagogical units: firstly, a psychiatrist providing a theoretical overview of mental illness and care and secondly, user-trainers describing their point of view on mental illness and exchanging with participants. A questionnaire administered at the beginning and at the end of the mental health awareness day assessed the impact of the day on participants' knowledge, beliefs, and desire for social distance. Answers to open questions were evaluated using thematic qualitative analysis. The intervention had statistically significant positive effects on all three training objectives: knowledge, beliefs and desire for social distance. Analysis of qualitative data confirmed participants' need for information and training with regard to providing support to clients with mental health problems; participants frequently attributed their improved self-confidence at the end of the day with regard to providing job coaching for this population group to the presence of user-trainers. A mental health awareness day using mental health service users and psychiatrists as trainers had significant positive effects in terms of reducing stigma with regard to people with mental illness. Further research is needed to understand whether the impact of such awareness approaches can be maintained in everyday professional practice over time. Copyright © 2013

  13. [Investigation of the educational effectiveness of including small group discussion as part of a drug abuse prevention program for junior high school students].

    Science.gov (United States)

    Yamada, Junichi; Takayanagi, Risa; Yokoyama, Haruko; Suzuki, Yasuhiro; Sinohara, Satomi; Yamada, Yasuhiko

    2014-01-01

    We evaluated the effectiveness of small group discussion (SGD) in association with a drug abuse prevention program for junior high school students. The students first received a lecture about drug abuse prevention, then participated in SGD. The discussion focused on how to take action when tempted to abuse drugs. We gave a questionnaire 3 times; before and after the lecture (before SGD), and after SGD. Seventy-seven students replied to these questionnaires. After the lecture, knowledge about drug abuse was improved and all students answered that they had never abused drugs. However, in answer to a different question, a few students noted that they might use drugs in some situations. We consider it necessary to give more consideration to this problem. After the lecture, 35.5% of the students felt that they had definitely acquired skills for drug abuse prevention, whereas after the SGD this was increased to 73.7%. In addition, more than 75% of the students answered that the SGD program was useful since the opinions of other students could be heard. These results suggest that more students acquired skills to prevent drug abuse by participation in SGD. Our findings showed that SGD was useful and that the students were able to more effectively understand important concepts related to drug abuse prevention.

  14. Irradiation, Annealing, and Reirradiation Effects on American and Russian Reactor Pressure Vessel Steels

    Energy Technology Data Exchange (ETDEWEB)

    Chernobaeva, A.A.; Korolev, Y.N.; Nanstad, R.K.; Nikolaev, Y.A.; Sokolov, M.A.

    1998-06-16

    One of the options to mitigate the effects of irradiation on reactor pressure vessels (RPVs) is to thermally anneal them to restore the toughness properties that have been degraded by neutron irradiation. Even though a postirradiation anneal may be deemed successful, a critical aspect of continued RPV operation is the rate of embrittlement upon reirradiation. There are insufficient data available to allow for verification of available models of reirradiation embrittlement or for the development of a reliable predictive methodology. This is especially true in the case of fracture toughness data. Under the U.S.-Russia Joint Coordinating Committee for Civilian Nuclear Reactor Safety (JCCCNRS), Working Group 3 on Radiation Embrittlement, Structural Integrity, and Life Extension of Reactor Vessels and Supports agreed to conduct a comparative study of annealing and reirradiation effects on RPV steels. The Working Group agreed that each side would irradiate, anneal, reirradiate (if feasible ), and test two materials of the other. Charpy V-notch (CVN) and tensile specimens were included. Oak Ridge National Laboratory (ORNL) conducted such a program (irradiation and annealing, including static fracture toughness) with two weld metals representative of VVER-440 and VVER-1000 RPVs, while the Russian Research Center-Kurchatov Institute (RRC-KI) conducted a program (irradiation, annealing, reirradiation, and reannealing) with Heavy-Section Steel Technology (HSST) Program Plate 02 and Heavy-Section Steel Irradiation (HSSI) Program Weld 73W. The results for each material from each laboratory are compared with those from the other laboratory. The ORNL experiments with the VVER welds included irradiation to about 1 x 10{sup 19} n/cm{sup 2} (>1 MeV), while the RRC-KI experiments with the U.S. materials included irradiations from about 2 to 18 x 10{sup 19} n/cm{sup 2} (>l MeV). In both cases, irradiations were conducted at {approximately}290 C and annealing treatments were conducted

  15. Continuing the Solar Irradiance Data Record with TSIS

    Science.gov (United States)

    Richard, E. C.; Pilewskie, P.; Kopp, G.; Coddington, O.; Woods, T. N.; Wu, D. L.

    2016-12-01

    The Total and Spectral Solar Irradiance Sensor (TSIS), first selected in 1998 for the National Polar-orbiting Operational Environmental Satellite System (NPOESS), re-manifested in 2010 on the NOAA-NASA Joint Polar Satellite System (JPSS), then the NOAA Polar Free Flyer, is now scheduled for deployment in 2017 on the International Space Station. The TSIS will acquire measurements of total and spectral solar irradiance (TSI and SSI, respectively). TSIS provides continuation of the Total Irradiance Monitor (TIM) and the Spectral Irradiance Monitor (SIM), currently flying on the NASA Solar Radiation and Climate Experiment (SORCE). Launched in 2003, SORCE is now more than eight years beyond its prime-mission lifetime. The launch failure of the NASA's Glory mission in 2011 coupled with diminished battery capacity on SORCE and delays in the launch of TSIS have put the continuous 38-year TSI record at risk. In 2012, a plan to maintain continuity of the TSI calibration scale between SORCE and TSIS was rapidly implemented through the USAF Space Test Program STPSat-3 that launched in late 2013. The shorter SSI record faces a likely gap between SORCE and TSIS. This paper summarizes the importance of highly accurate and stable observations of solar irradiance in understanding the present climate epoch and for predicting future climate; why continuity in the solar irradiance data record is required; improvements in the TSIS TIM and SIM, including verification of their calibration using ground-based NIST-traceable cryogenic standards; and how these improvements will impact Sun-climate studies in the near future.

  16. Thermal outgassing of irradiated nuclear fuel: a literature review

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, L.G.; Matsuzaki, C.L.; Burger, L.L.; Bray, L.A.

    1984-07-01

    An experimental program at PNL examined the release of volatile and semivolatile radionuclides from irradiated nuclear fuel under different modes of heat treatment. In support of this work, a literature evaluation was conducted to review the information on: physical changes in fuel and cladding; distribution, migration, and reactions of fission products; and theoretical studies. Omitted from the review are evaluations of various fission gas bubble behavior - swelling models. The different computer codes that have been used to predict fuel behavior are also not included. A large amount of work has been done on the behavior of nuclear fuels during irradiation. The goals of this work have been to ensure acceptable mechanical performance, provide safe operation, and assist in fuel design, preparation, and recycle. Many fundamental studies, including diffusion and lattice structures, are also reported. 51 references, 17 figures, 8 tables.

  17. Currently developing opportunities in food irradiation and modern irradiation facilities

    Energy Technology Data Exchange (ETDEWEB)

    Wanke, R. [Director Business Development. SteriGenics International Inc. 17901 East Warren Avenue No. 4, Detroit, Michigan 48224-1333 (United States)

    1997-12-31

    I. Factor currently influencing advancing opportunities for food irradiation include: heightened incidence and awareness of food borne illnesses and causes. Concerns about ensuring food safety in international as well as domestic trade. Regulatory actions regarding commonly used fumigants/pesticides e.g. Me Br. II. Modern irradiator design: the SteriGenics {sup M}ini Cell{sup .} A new design for new opportunities. Faster installation of facility. Operationally and space efficient. Provides local {sup o}nsite control{sup .} Red meat: a currently developing opportunity. (Author)

  18. (Irradiation creep of graphite)

    Energy Technology Data Exchange (ETDEWEB)

    Kennedy, C.R.

    1990-12-21

    The traveler attended the Conference, International Symposium on Carbon, to present an invited paper, Irradiation Creep of Graphite,'' and chair one of the technical sessions. There were many papers of particular interest to ORNL and HTGR technology presented by the Japanese since they do not have a particular technology embargo and are quite open in describing their work and results. In particular, a paper describing the failure of Minor's law to predict the fatigue life of graphite was presented. Although the conference had an international flavor, it was dominated by the Japanese. This was primarily a result of geography; however, the work presented by the Japanese illustrated an internal program that is very comprehensive. This conference, a result of this program, was better than all other carbon conferences attended by the traveler. This conference emphasizes the need for US participation in international conferences in order to stay abreast of the rapidly expanding HTGR and graphite technology throughout the world. The United States is no longer a leader in some emerging technologies. The traveler was surprised by the Japanese position in their HTGR development. Their reactor is licensed and the major problem in their graphite program is how to eliminate it with the least perturbation now that most of the work has been done.

  19. Food Preservation by Irradiation (Rev.)

    Energy Technology Data Exchange (ETDEWEB)

    Urrows, Grace M.

    1968-01-01

    Up to 30% of food harvests are lost in some parts of the world because of animal pests and microorganisms. Nuclear techniques can help reduce and extend the shelf life of these foods. Around 55 countries now have food irradiation programs. The use of radiation is the most recent step in man's attempts to preserve some of his harvest for the lean part of the year.

  20. Pelvic floor muscle training included in a pregnancy exercise program is effective in primary prevention of urinary incontinence: a randomized controlled trial.

    Science.gov (United States)

    Pelaez, Mireia; Gonzalez-Cerron, Silvia; Montejo, Rocío; Barakat, Rubén

    2014-01-01

    To investigate the effect of pelvic floor muscle training (PFMT) taught in a general exercise class during pregnancy on the prevention of urinary incontinence (UI) in nulliparous continent pregnant women. This was a unicenter two armed randomized controlled trial. One hundred sixty-nine women were randomized by a central computer system to an exercise group (EG) (exercise class including PFMT) (n = 73) or a control group (CG) (n = 96). 10.1% loss to follow-up: 10 from EG and 7 from CG. The intervention consisted of 70-75 sessions (22 weeks, three times per week, 55-60 min/session including 10 min of PFMT). The CG received usual care (which included follow up by midwifes including information about PFMT). Questions on prevalence and degree of UI were posed before (week 10-14) and after intervention (week 36-39) using the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF). At the end of the intervention, there was a statistically significant difference in favor of the EG. Reported frequency of UI [Never: CG: 54/60.7%, EG: 60/95.2% (P prevention of UI in primiparous pregnant women. © 2013 Wiley Periodicals, Inc.

  1. AGR-1 Irradiation Test Final As-Run Report

    Energy Technology Data Exchange (ETDEWEB)

    Blaise P. Collin

    2012-06-01

    This document presents the as-run analysis of the AGR-1 irradiation experiment. AGR-1 is the first of eight planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the US Department of Energy (DOE) as part of the Next-Generation Nuclear Plant (NGNP) project. The objectives of the AGR-1 experiment are: 1. To gain experience with multi-capsule test train design, fabrication, and operation with the intent to reduce the probability of capsule or test train failure in subsequent irradiation tests. 2. To irradiate fuel produced in conjunction with the AGR fuel process development effort. 3. To provide data that will support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. In order to achieve the test objectives, the AGR-1 experiment was irradiated in the B-10 position of the Advanced Test Reactor (ATR) at the Idaho National Laboratory (INL) for a total duration of 620 effective full power days of irradiation. Irradiation began on December 24, 2006 and ended on November 6, 2009 spanning 13 ATR cycles and approximately three calendar years. The test contained six independently controlled and monitored capsules. Each capsule contained 12 compacts of a single type, or variant, of the AGR coated fuel. No fuel particles failed during the AGR-1 irradiation. Final burnup values on a per compact basis ranged from 11.5 to 19.6 %FIMA, while fast fluence values ranged from 2.21 to 4.39 ?1025 n/m2 (E >0.18 MeV). We’ll say something here about temperatures once thermal recalc is done. Thermocouples performed well, failing at a lower rate than expected. At the end of the irradiation, nine of the originally-planned 19 TCs were considered functional. Fission product release-to-birth (R/B) ratios were quite low. In most capsules, R/B values at the end of the irradiation were at or below 10-7 with only one

  2. Irradiation as an alternative post harvest treatment

    Energy Technology Data Exchange (ETDEWEB)

    Satin, M. [Agricultural Industries and Post-harvest Management Service, FAO, Rome (Italy); Loaharanu, P. [Head, Food Preservation Section, Joint FAO/ IAEA Division of Nuclear Techniques in Food and Agriculture, Wagramerstr. 5, A-1400, Vienna (Austria)

    1997-12-31

    This current world population has significantly added to the pressures placed upon our finite resources and our resulting ability to feed ourselves. In order to cope with current and future demands, the two established lines of action, that is, reduced population growth and expansion of agricultural production, must be supplemented with the parallel activity of reducing food losses during and after harvest. For developing countries in particular, enormous post-harvest losses result from spillage, contamination, pests and physiological deterioration during storage. Studies in these countries indicate that post-harvest losses are enormous and amount to tens of millions of tons per year valued at billions of dollars. Programs to reduce post-harvest losses, if applied properly, can result in realistic yield increases between 10 and 30%, which can be directly converted into increased consumption for humans. Post-harvest losses vary greatly and are a function of the crop variety, pest combinations in the environment, climate, the system of harvesting, storage, handling, marketing, and even the social and cultural environment. Pests are among the most criticals of these factors. Because of the disastrous potential consequences of such pests, quarantine regulations prohibit the entrance of plants or products which might hide the unwanted pest from countries where it is known to exist. Quarantine treatments are can be chemical, physical or ionizing radiation treatment. Numerous investigations on the use of ionizing radiation for the disinfestation of fresh plant materials indicate that rather low dosages will control fruit-fly problems, thus making it well suited for quarantine treatment. The effectiveness of the irradiation as a broad spectrum quarantine treatment of fresh fruits and vegetables was recognized by the several plant protection organizations around the world. Currently, some 40 countries have approved one or more irradiated food items or groups of food

  3. Comparison of LC–MS-MS and GC–MS Analysis of Benzodiazepine Compounds Included in the Drug Demand Reduction Urinalysis Program

    Science.gov (United States)

    Perez, Erick Roman; Knapp, Joshua A.; Horn, Carl K.; Stillman, Stedra L.; Evans, James E.; Arfsten, Darryl P.

    2016-01-01

    Liquid chromatography–tandem mass spectrometry (LC–MS-MS) offers specific advantages over gas chromatography–mass spectrometry (GC–MS) such as the ability to identify and measure a broader range of compounds with minimal sample preparation. Comparative analysis of LC–MS-MS versus GC–MS was performed for urinalysis detection of five benzodiazepine compounds currently part of the Department of Defense (DoD) Drug Demand Reduction Program (DDRP) testing panel; alpha-hydroxyalprazolam, oxazepam, lorazepam, nordiazepam and temazepam. In the analyses of internally prepared control urine samples at concentrations around the DDRP administrative decision point for benzodiazepines (100 ng/mL), both technologies produced comparable results with average accuracies between 99.7 and 107.3% and average coefficients of variation (%CV) MS-MS analysis. However, the effects were controlled by using deuterated internal standards (ISTDs). Additionally, there was a 39% increase in nordiazepam mean concentration analyzed by LC–MS-MS due to suppression of the ISTD ion by the flurazepam metabolite 2-hydroxyethylflurazepam. The ease and speed of sample extraction, the broader range of compounds that can be analyzed and shorter run time make the LC–MS-MS technology a suitable and expedient alternative confirmation technology for benzodiazepine testing. PMID:26755538

  4. Tomato Ribonuclease LX with the Functional Endoplasmic Reticulum Retention Motif HDEF Is Expressed during Programmed Cell Death Processes, Including Xylem Differentiation, Germination, and Senescence1

    Science.gov (United States)

    Lehmann, Karin; Hause, Bettina; Altmann, Dorit; Köck, Margret

    2001-01-01

    We have studied the subcellular localization of the acid S-like ribonuclease (RNase) LX in tomato (Lycopersicon esculentum Mill.) cells using a combination of biochemical and immunological methods. It was found that the enzyme, unexpectedly excluded from highly purified vacuoles, accumulates in the endoplasmic reticulum. The evidence that RNase LX is a resident of the endoplasmic reticulum (ER) is supported by an independent approach showing that the C-terminal peptide HDEF of RNase LX acts as an alternative ER retention signal in plants. For functional testing, the cellular distribution of chimeric protein constructs based on a marker protein, Brazil nut (Bertholletia excelsa) 2S albumin, was analyzed immunochemically in transgenic tobacco (Nicotiana tabacum) plants. Here, we report that the peptide motif is necessary and sufficient to accumulate 2S albumin constructs of both vacuolar and extracellular final destinations in the ER. We have shown immunochemically that RNase LX is specifically expressed during endosperm mobilization and leaf and flower senescence. Using immunofluorescence, RNase LX protein was detected in immature tracheary elements, suggesting a function in xylem differentiation. These results support a physiological function of RNase LX in selective cell death processes that are also thought to involve programmed cell death. It is assumed that RNase LX accumulates in an ER-derived compartment and is released by membrane disruption into the cytoplasma of those cells that are intended to undergo autolysis. These processes are accompanied by degradation of cellular components supporting a metabolic recycling function of the intracellular RNase LX. PMID:11598219

  5. Food irradiation: Gamma processing facilities

    Energy Technology Data Exchange (ETDEWEB)

    Kunstadt, P. [MDS Nordion International, 447 March Road. Kanata, Ontario, K2K148 (Canada)

    1997-12-31

    The number of products being radiation processed is constantly increasing and today include such diverse items as medical disposable, fruits and vegetables, bulk spices, meats, sea foods and waste effluents. Not only do the products differ but also many products, even those within the same groupings, require different minimum and maximum radiation doses. These variations create many different requirements in the irradiator design. The design of Cobalt-60 radiation processing facilities is well established for a number of commercial applications. Installations in over 40 countries, with some in operation since the early 1960s, are testimony to the fact that irradiator design, manufacture, installation and operation is a well established technology. However, in order to design gamma irradiators for the preservation of foods one must recognize those parameters typical to the food irradiation process as well as those systems and methods already well established in the food industry. This paper discusses the basic design concepts for gamma food irradiators. They are most efficient when designed to handle a limited product density range at an established dose. Safety of Cobalt-60 transport, safe facility operation principles and the effect of various processing parameters on economics, will also be discussed. (Author)

  6. Elective ilioingunial lymph node irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, R.H.; Parsons, J.T.; Morgan, L.; Million, R.R.

    1984-06-01

    Most radiologists accept that modest doses of irradiation (4500-5000 rad/4 1/2-5 weeks) can control subclinical regional lymph node metastases from squamous cell carcinomas of the head and neck and adenocarcinomas of the breast. There have been few reports concerning elective irradiation of the ilioinguinal region. Between October 1964 and March 1980, 91 patients whose primary cancers placed the ilioinguinal lymph nodes at risk received elective irradiation at the University of Florida. Included are patients with cancers of the vulva, penis, urethra, anus and lower anal canal, and cervix or vaginal cancers that involved the distal one-third of the vagina. In 81 patients, both inguinal areas were clinically negative; in 10 patients, one inguinal area was positive and the other negative by clinical examination. The single significant complication was a bilateral femoral neck fracture. The inguinal areas of four patients developed mild to moderate fibrosis. One patient with moderate fibrosis had bilateral mild leg edema that was questionably related to irradiation. Complications were dose-related. The advantages and dis-advantages of elective ilioinguinal node irradiation versus elective inguinal lymph node dissection or no elective treatment are discussed.

  7. Directional irradiances and fractional clouds

    Science.gov (United States)

    Pagh Nielsen, Kristian; Andersen, Elsa; Dragsted, Janne; Furbo, Simon

    2017-04-01

    For large scale implementation of solar energy, better understanding of the directional and temporal variations in the solar resource is needed. This includes understanding the shading within a multiple row field of solar panels and how this affects the electricity or heat production. We have studied directional irradiances measured simultaneously from 16 downward directions at 1 minute temporal resolution. Also, we have performed measurements of the variations in the field of view across individual solar heating panels in the operational solar district heating plant in Hedehusene in Denmark. By combining a model of directional diffuse irradiances with the field of view variation across a solar panel in a solar panel field we can quantify the effect of shading of diffuse irradiances on the heat flow from the panel.

  8. Impact of Biological Feedback and Incentives on Blood Fatty Acid Concentrations, Including Omega-3 Index, in an Employer-Based Wellness Program.

    Science.gov (United States)

    McBurney, Michael I; Bird, Julia K

    2017-08-05

    Eicosapentaenoic acid (EPA, C20:5n-3) and docosahexaenoic acid (DHA, C22:6n-3) are important fatty acids for the retina and brain. More than 95% of Americans have suboptimal EPA + DHA blood concentrations. This cross-sectional employer-based study assessed whole blood fatty acid levels of volunteers participating in an onsite wellness biometric screening program and was designed to determine if an incentive, a $5 coupon for a 90-day supply of fish oil supplement typically costing $18-30, stimulated incremental dietary behavior change relative to nutritional status assessment alone to increase EPA + DHA concentrations. Volunteers completed a dietary survey and finger stick blood samples were collected to be analyzed for fatty acid composition. In addition, 636 individuals participated in the initial onsite biometric screening. Three months later, and without prior knowledge, all employees were invited to a second screening. At the second screening, 198 employees volunteered for the first time and 149 employees had a second test (17.9%). At baseline, the average age (n = 834) was 45 year and omega-3 index was 5.0% with 41% female. EPA + DHA concentration, i.e., omega-3 index, was significantly lower in men (4.8%) than women (5.2%), as were DHA and linoleic acid (LA) concentrations (p omega-3 index was positively and linearly associated with omega-3 intake. Only 4% of volunteers had an omega-3 index >8% on initial screening. Among the 149 individuals with two measurements, omega-3 intake from supplements, but not food, increased significantly from 258 to 445 mg/d (p omega-3 index (+0.21, p omega-3 supplement.

  9. Impact of Biological Feedback and Incentives on Blood Fatty Acid Concentrations, Including Omega-3 Index, in an Employer-Based Wellness Program

    Directory of Open Access Journals (Sweden)

    Michael I. McBurney

    2017-08-01

    Full Text Available Eicosapentaenoic acid (EPA, C20:5n-3 and docosahexaenoic acid (DHA, C22:6n-3 are important fatty acids for the retina and brain. More than 95% of Americans have suboptimal EPA + DHA blood concentrations. This cross-sectional employer-based study assessed whole blood fatty acid levels of volunteers participating in an onsite wellness biometric screening program and was designed to determine if an incentive, a $5 coupon for a 90-day supply of fish oil supplement typically costing $18–30, stimulated incremental dietary behavior change relative to nutritional status assessment alone to increase EPA + DHA concentrations. Volunteers completed a dietary survey and finger stick blood samples were collected to be analyzed for fatty acid composition. In addition, 636 individuals participated in the initial onsite biometric screening. Three months later, and without prior knowledge, all employees were invited to a second screening. At the second screening, 198 employees volunteered for the first time and 149 employees had a second test (17.9%. At baseline, the average age (n = 834 was 45 year and omega-3 index was 5.0% with 41% female. EPA + DHA concentration, i.e., omega-3 index, was significantly lower in men (4.8% than women (5.2%, as were DHA and linoleic acid (LA concentrations (p < 0.05. Baseline omega-3 index was positively and linearly associated with omega-3 intake. Only 4% of volunteers had an omega-3 index >8% on initial screening. Among the 149 individuals with two measurements, omega-3 intake from supplements, but not food, increased significantly from 258 to 445 mg/d (p < 0.01 at the second test as did the omega-3 index (+0.21, p < 0.02. In this employed population, only 1% redeemed a coupon for an omega-3 supplement.

  10. Quality assurance program of a respiratory gating irradiation system based on external and internal fiducial markers; Programa de garantia de calidad de un sistema de irradiacion con control respiratorio basado en marcadores fiduciales externos e internos

    Energy Technology Data Exchange (ETDEWEB)

    Zucca Aparicio, D.; Perez Moreno, J. M.; Fernandez Leton, P.; Garcia Ruiz-Zorrilla, J.; Minambres Moro, A.

    2011-07-01

    Respiratory Gating involves the administration of radiation during treatment delivery within a particular portion of the patients breathing cycle, so the absorbed dose administration with respiratory control techniques requires specific quality control to ensure the correctness of the delivered dose. The establishment of a Quality Control Program (QC) is proposed for the Respiratory Gating based techniques in order to have a better understanding of how this system works and to know its associated dosimetric impact. The influence of the CT acquisition under respiratory motion conditions has been analyzed for the treatment isocenter localization, using internal and external fiducial markers with IGRT techniques that allow the correlation of the isocenter positioning with the phase of the respiratory cycle. Radiation delivery in the presence of intra fraction organ motion causes an averaging or blurring of the static dose distribution over the path of motion increasing the beam penumbra of the radiation field and reducing the therapeutic region when the irradiation is not breath controlled. The feasibility of intensity modulated treatments (IMRT) for both static and dynamic techniques, managed by respiratory control has been tested, demonstrating the possibility of synchronizing the movement of the leaves in the microfluorimeter collimator (mMLC) with the gated beam irradiation. (Author) 45 refs.

  11. Project HAPI (Handicapped Achievement Program Improvement): Assessment plus Intervention equal I.E.P. A Handbook on How To Write an Individualized Education Program for Severe Disorders of Language, Including Aphasia and Other Speech-Language Handicapped (Communication Disorders). Book One.

    Science.gov (United States)

    Chapman, Jean

    The first of five handbooks developed by Project HAPI (Handicapped Achievement Program Improvement), a multimedia staff development program to help teachers and specialists write effective individualized education programs (IEPs), is in looseleaf workbook format and focuses on children with severe disorders of language, including aphasia and other…

  12. Regulations on consume and commercialization of food irradiation in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez, M.E.B. [Instituto Nacional de Investigaciones Nucleares, Mexico City (Mexico); Perez, J.J. [Direccion de Normalizacion Sanitaria (Mexico)

    1995-10-01

    A Mexican standard for food irradiation is ready for final publication after the authority received and reviewed public comments of the project published in April 1994. The standard establish the radiation doses for different classes of food, based on ICGFI recommendations. Also included are controls for sampling, packaging, labelling, transportation, process inspection and accordance with international regulations. The results of the economical analysis of cost-benefit of the application of the standard show that the net present value is positive. The method of calculation is presented explaining the assumptions considered for the estimation of the total annual savings and surveillance costs. A final version of the research program report on radiation quarantine treatment of Mexican mangoes will be used for the petition to APHIS for the amendment of quarantine procedures to permit importation into the USA of irradiated products. (Author).

  13. KEY RESULTS FROM IRRADIATION AND POST-IRRADIATION EXAMINATION OF AGR-1 UCO TRISO FUEL

    Energy Technology Data Exchange (ETDEWEB)

    Demkowicz, Paul A.; Hunn, John D.; Petti, David A.; Morris, Robert N.

    2016-11-01

    The AGR-1 irradiation experiment was performed as the first test of tristructural isotropic (TRISO) fuel in the US Advanced Gas Reactor Fuel Development and Qualification Program. The experiment consisted of 72 right cylinder fuel compacts containing approximately 3×105 coated fuel particles with uranium oxide/uranium carbide (UCO) fuel kernels. The fuel was irradiated in the Advanced Test Reactor for a total of 620 effective full power days. Fuel burnup ranged from 11.3 to 19.6% fissions per initial metal atom and time average, volume average irradiation temperatures of the individual compacts ranged from 955 to 1136°C. This paper focuses on key results from the irradiation and post-irradiation examination, which revealed a robust fuel with excellent performance characteristics under the conditions tested and have significantly improved the understanding of UCO coated particle fuel irradiation behavior within the US program. The fuel exhibited a very low incidence of TRISO coating failure during irradiation and post-irradiation safety testing at temperatures up to 1800°C. Advanced PIE methods have allowed particles with SiC coating failure to be isolated and meticulously examined, which has elucidated the specific causes of SiC failure in these specimens. The level of fission product release from the fuel during irradiation and post-irradiation safety testing has been studied in detail. Results indicated very low release of krypton and cesium through intact SiC and modest release of europium and strontium, while also confirming the potential for significant silver release through the coatings depending on irradiation conditions. Focused study of fission products within the coating layers of irradiated particles down to nanometer length scales has provided new insights into fission product transport through the coating layers and the role various fission products may have on coating integrity. The broader implications of these results and the application of

  14. AGC-1 Post Irradiation Examination Status

    Energy Technology Data Exchange (ETDEWEB)

    David Swank

    2011-09-01

    The Next Generation Nuclear Plant (NGNP) Graphite R&D program is currently measuring irradiated material property changes in several grades of nuclear graphite for predicting their behavior and operating performance within the core of new Very High Temperature Reactor (VHTR) designs. The Advanced Graphite Creep (AGC) experiment consisting of six irradiation capsules will generate this irradiated graphite performance data for NGNP reactor operating conditions. All six AGC capsules in the experiment will be irradiated in the Advanced Test Reactor (ATR), disassembled in the Hot Fuel Examination Facility (HFEF), and examined at the INL Research Center (IRC) or Oak Ridge National Laboratory (ORNL). This is the first in a series of status reports on the progress of the AGC experiment. As the first capsule, AGC1 was irradiated from September 2009 to January 2011 to a maximum dose level of 6-7 dpa. The capsule was removed from ATR and transferred to the HFEF in April 2011 where the capsule was disassembled and test specimens extracted from the capsules. The first irradiated samples from AGC1 were shipped to the IRC in July 2011and initial post irradiation examination (PIE) activities were begun on the first 37 samples received. PIE activities continue for the remainder of the AGC1 specimen as they are received at the IRC.

  15. Comparison of irradiated 15Kh2MFA material mechanical properties using conventional testing methods and innovative approach of small punch testing (SPT) and automated ball indentation (ABIT)

    Science.gov (United States)

    Kopriva, R.; Petelova, P.; Eliasova, I.; Kytka, M.; Culek, M.

    2017-02-01

    Article describes two innovative testing methods - Small Punch Testing (SPT) and Automated Ball Indentation Test (ABIT) - which are based on the determination and evaluation of material properties from miniaturized testing specimens. These methods are very promising due to minimum material needed for testing and also in case of testing highly irradiated materials of components that are not included in standard surveillance programs. The test results were obtained for reactor pressure vessel (RPV) base material 15Ch2MFA in both states - initial unirradiated and irradiated. Subsequently results were compared with standard tensile tests to prove applicability of these testing methods for the evaluation of degradation of irradiated structural materials of nuclear power plants.

  16. Dummy Run of Quality Assurance Program in a Phase 3 Randomized Trial Investigating the Role of Internal Mammary Lymph Node Irradiation in Breast Cancer Patients: Korean Radiation Oncology Group 08-06 Study

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yoonsun [Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (Korea, Republic of); Kim, Jun Won [Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of); Shin, Kyung Hwan [Department of Radiation Oncology, Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang (Korea, Republic of); Kim, Su Ssan [Department of Radiation Oncology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul (Korea, Republic of); Ahn, Sung-Ja [Department of Radiation Oncology, Chonnam National University Medical School, Gwangju (Korea, Republic of); Park, Won [Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Lee, Hyung-Sik [Department of Radiation Oncology, Dong-A University Hospital, Dong-A University School of Medicine, Busan (Korea, Republic of); Kim, Dong Won [Department of Radiation Oncology, Pusan National University Hospital, Pusan National University School of Medicine, Busan (Korea, Republic of); Lee, Kyu Chan [Department of Radiation Oncology, Gachon University Gil Medical Center, Incheon (Korea, Republic of); Suh, Hyun Suk [Department of Radiation Oncology, Ewha Womans University Mokdong Hospital, Seoul (Korea, Republic of); Kim, Jin Hee [Department of Radiation Oncology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu (Korea, Republic of); Shin, Hyun Soo [Department of Radiation Oncology, Bundang CHA Hospital, School of Medicine, CHA University, Seongnam (Korea, Republic of); Kim, Yong Bae, E-mail: ybkim3@yuhs.ac [Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (Korea, Republic of); Suh, Chang-Ok [Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (Korea, Republic of)

    2015-02-01

    Purpose: The Korean Radiation Oncology Group (KROG) 08-06 study protocol allowed radiation therapy (RT) technique to include or exclude breast cancer patients from receiving radiation therapy to the internal mammary lymph node (IMN). The purpose of this study was to assess dosimetric differences between the 2 groups and potential influence on clinical outcome by a dummy run procedure. Methods and Materials: All participating institutions were asked to produce RT plans without irradiation (Arm 1) and with irradiation to the IMN (Arm 2) for 1 breast-conservation treatment case (breast-conserving surgery [BCS]) and 1 mastectomy case (modified radical mastectomy [MRM]) whose computed tomography images were provided. We assessed interinstitutional variations in IMN delineation and evaluated the dose-volume histograms of the IMN and normal organs. A reference IMN was delineated by an expert panel group based on the study guidelines. Also, we analyzed the potential influence of actual dose variation observed in this study on patient survival. Results: Although physicians intended to exclude the IMN within the RT field, the data showed almost 59.0% of the prescribed dose was delivered to the IMN in Arm 1. However, the mean doses covering the IMN in Arm 1 and Arm 2 were significantly different for both cases (P<.001). Due to the probability of overdose in Arm 1, the estimated gain in 7-year disease-free survival rate would be reduced from 10% to 7.9% for BCS cases and 7.1% for MRM cases. The radiation doses to the ipsilateral lung, heart, and coronary artery were lower in Arm 1 than in Arm 2. Conclusions: Although this dummy run study indicated that a substantial dose was delivered to the IMN, even in the nonirradiation group, the dose differences between the 2 groups were statistically significant. However, this dosimetric profile should be studied further with actual patient samples and be taken into consideration when analyzing clinical outcomes according to IMN

  17. Food irradiation: Standards, regulations and world-wide trade

    Science.gov (United States)

    Roberts, Peter B.

    2016-12-01

    There is an established framework of international standards for food irradiation covering human health, plant protection, labelling, dose delivery, quality assurance and facility management. Approximately 60 countries permit irradiation of one or more food or food classes. National regulations are briefly reviewed. Decontamination of spices, herbs and condiments remains the single largest application of irradiation. However, in recent years the market for irradiated fresh and processed meat has become firmly established in several countries including China and the USA. At least 10 countries have recently established bi-lateral agreements for trade in irradiated fresh fruits and vegetables using phytosanitary irradiation. Irradiated fresh produce volumes now exceed 20,000 t per year. Rationalization and greater consistency in labelling regulations would be advantageous to the future growth of applications of food irradiation.

  18. Detection of low amount of irradiated ingredients in non-irradiated precooked meals

    NARCIS (Netherlands)

    Marchioni, E; Horvatovich, P; Ndiaye, B; Miesch, M; Hasselmann, C

    The application of the European Standards for the detection of irradiated food by thermo luminescence of silicates, electron-spin resonance spectroscopy of bones or gas chromatography-mass spectrometry of 2-alkylcyclobutanones does not allow the detection of irradiated ingredients included in small

  19. Solar Spectral Irradiance and Climate

    Science.gov (United States)

    Pilewskie, P.; Woods, T.; Cahalan, R.

    2012-01-01

    Spectrally resolved solar irradiance is recognized as being increasingly important to improving our understanding of the manner in which the Sun influences climate. There is strong empirical evidence linking total solar irradiance to surface temperature trends - even though the Sun has likely made only a small contribution to the last half-century's global temperature anomaly - but the amplitudes cannot be explained by direct solar heating alone. The wavelength and height dependence of solar radiation deposition, for example, ozone absorption in the stratosphere, absorption in the ocean mixed layer, and water vapor absorption in the lower troposphere, contribute to the "top-down" and "bottom-up" mechanisms that have been proposed as possible amplifiers of the solar signal. New observations and models of solar spectral irradiance are needed to study these processes and to quantify their impacts on climate. Some of the most recent observations of solar spectral variability from the mid-ultraviolet to the near-infrared have revealed some unexpected behavior that was not anticipated prior to their measurement, based on an understanding from model reconstructions. The atmospheric response to the observed spectral variability, as quantified in climate model simulations, have revealed similarly surprising and in some cases, conflicting results. This talk will provide an overview on the state of our understanding of the spectrally resolved solar irradiance, its variability over many time scales, potential climate impacts, and finally, a discussion on what is required for improving our understanding of Sun-climate connections, including a look forward to future observations.

  20. Total and Spectral Solar Irradiance Sensor (TSIS) Project Overview

    Science.gov (United States)

    Carlisle, Candace; Wedge, Ronnice; Wu, Dong; Stello, Harry; Robinson, Renee

    2015-01-01

    The main objective of the Total and Spectral solar Irradiance Sensor (TSIS) is to acquire measurements to determine the direct and indirect effects of solar radiation on climate. TSIS total solar irradiance measurements will extend a 37-year long uninterrupted measurement record of incoming solar radiation, the dominant energy source driving the Earths climate and the most precise indicator of changes in the Suns energy output. TSIS solar spectral irradiance measurements will determine the regions of the Earths multi-layered atmosphere that are affected by solar variability, from which the solar forcing mechanisms causing changes in climate can be quantified. TSIS includes two instruments: the Total Irradiance Monitor (TIM) and the Spectral Irradiance Monitor (SIM), integrated into a single payload. The TSIS TIM and SIM instruments are upgraded versions of the two instruments that are flying on the Solar Radiation and Climate Experiment (SORCE) mission launched in January 2003. TSIS was originally planned for the nadir-pointing National Polar-orbiting Operational Environmental Satellite System (NPOESS) spacecraft. The TSIS instrument passed a Critical Design Review (CDR) for NPOESS in December 2009. In 2010, TSIS was re-planned for the Joint Polar Satellite System (JPSS) Polar Free Flyer (PFF). The TSIS TIM, SIM, and associated electronics were built, tested, and successfully completed pre-ship review as of December 2013.In early 2014, NOAA and NASA agreed to fly TSIS on the International Space Station (ISS). In the FY16 Presidents Budget, NASA assumes responsibility for the TSIS mission on ISS. The TSIS project includes requirements, interface, design, build and test of the TSIS payload, including an updated pointing system, for accommodation on the ISS. It takes advantage of the prior development of the TSIS sensors and electronics. The International Space Station (ISS) program contributions include launch services and robotic installation of the TSIS payload

  1. Microarchitecture of irradiated bone: comparison with healthy bone

    Science.gov (United States)

    Bléry, Pauline; Amouriq, Yves; Guédon, Jeanpierre; Pilet, Paul; Normand, Nicolas; Durand, Nicolas; Espitalier, Florent; Arlicot, Aurore; Malard, Olivier; Weiss, Pierre

    2012-03-01

    The squamous cell carcinomas of the upper aero-digestive tract represent about ten percent of cancers. External radiation therapy leads to esthetic and functional consequences, and to a decrease of the bone mechanical abilities. For these patients, the oral prosthetic rehabilitation, including possibilities of dental implant placement, is difficult. The effects of radiotherapy on bone microarchitecture parameters are not well known. Thus, the purpose of this study is to assess the effects of external radiation on bone micro architecture in an experimental model of 25 rats using micro CT. 15 rats were irradiated on the hind limbs by a single dose of 20 Grays, and 10 rats were non irradiated. Images of irradiated and healthy bone were compared. Bone microarchitecture parameters (including trabecular thickness, trabecular number, trabecular separation, connectivity density and tissue and bone volume) between irradiated and non-irradiated bones were calculated and compared using a Mann and Whitney test. After 7 and 12 weeks, images of irradiated and healthy bone are different. Differences on the irradiated and the healthy bone populations exhibit a statistical significance. Trabecular number, connectivity density and closed porosity are less important on irradiated bone. Trabecular thickness and separation increase for irradiated bone. These parameters indicate a decrease of irradiated bone properties. Finally, the external irradiation induces changes on the bone micro architecture. This knowledge is of prime importance for better oral prosthetic rehabilitation, including implant placement.

  2. Irradiation Creep in Graphite

    Energy Technology Data Exchange (ETDEWEB)

    Ubic, Rick; Butt, Darryl; Windes, William

    2014-03-13

    An understanding of the underlying mechanisms of irradiation creep in graphite material is required to correctly interpret experimental data, explain micromechanical modeling results, and predict whole-core behavior. This project will focus on experimental microscopic data to demonstrate the mechanism of irradiation creep. High-resolution transmission electron microscopy should be able to image both the dislocations in graphite and the irradiation-induced interstitial clusters that pin those dislocations. The team will first prepare and characterize nanoscale samples of virgin nuclear graphite in a transmission electron microscope. Additional samples will be irradiated to varying degrees at the Advanced Test Reactor (ATR) facility and similarly characterized. Researchers will record microstructures and crystal defects and suggest a mechanism for irradiation creep based on the results. In addition, the purchase of a tensile holder for a transmission electron microscope will allow, for the first time, in situ observation of creep behavior on the microstructure and crystallographic defects.

  3. Measurements of the angular distribution of diffuse irradiance

    DEFF Research Database (Denmark)

    Andersen, Elsa; Nielsen, Kristian Pagh; Dragsted, Janne

    2015-01-01

    Advanced solar resource assessment and forecasting is necessary for optimal solar energy utilization. In order to investigate the short-term resource variability, for instance caused by clouds it is necessary to investigate how clouds affect the solar irradiance, including the angular distribution...... of the solar irradiance. The investigation is part of the Danish contribution to the taskforce 46 within the International Energy Agency and financed by the Danish Energy Agency. The investigation focuses on the distribution of the diffuse solar irradiance and is based on horizontal measurements of the solar...... irradiance from 8 different parts of the sky as well as horizontal measurements of the total beam and total diffuse irradiance....

  4. Bronchiolitis obliterans. A new clinical-pathologic complication of irradiation pneumonitis

    Energy Technology Data Exchange (ETDEWEB)

    Kaufman, J.; Komorowski, R. (Medical College of Wisconsin, Milwaukee (USA))

    1990-05-01

    A patient underwent chest irradiation for small-cell carcinoma of the left lung. Several weeks following cessation of irradiation, the patient developed hypoxemia and reticulonodular densities within the radiation port. Open lung biopsy yielded a pathologic diagnosis consistent with irradiation pneumonitis along with a previously unreported association, bronchiolitis obliterans. Bronchiolitis obliterans should be included in the pathologic description of irradiation pneumonitis.

  5. Irradiation in adulthood as a new model of schizophrenia.

    Directory of Open Access Journals (Sweden)

    Yasuhide Iwata

    Full Text Available BACKGROUND: Epidemiological studies suggest that radiation exposure may be a potential risk factor for schizophrenia in adult humans. Here, we investigated whether adult irradiation in rats caused behavioral abnormalities relevant to schizophrenia. METHODOLOGY/PRINCIPAL FINDINGS: A total dose of 15-Gy irradiation in six fractionations during 3 weeks was exposed to the forebrain including the subventricular zone (SVZ and subgranular zone (SGZ with male rats in the prone position. Behavioral, immunohistochemical, and neurochemical studies were performed three months after fractionated ionizing irradiation. Three months after fractionated ionizing irradiation, the total numbers of BrdU-positive cells in both the SVZ and SGZ zones of irradiated rats were significantly lower than those of control (sham-irradiated rats. Hyperactivity after administration of the dopaminergic agonist methamphetamine, but not the N-methyl-D-aspartate (NMDA receptor antagonist dizocilpine, was significantly enhanced in the irradiated rats although spontaneous locomotion in the irradiated rats was significantly lower than that of controls. Behavioral abnormalities including auditory sensory gating deficits, social interaction deficits, and working memory deficits were observed in the irradiated rats. CONCLUSION/SIGNIFICANCE: The present study suggests that irradiation in adulthood caused behavioral abnormalities relevant to schizophrenia, and that reduction of adult neurogenesis by irradiation may be associated with schizophrenia-like behaviors in rats.

  6. [The intraoperative irradiation of tumors].

    Science.gov (United States)

    Zyrianov, B N; Chakhlov, V L; Khodkevich, B S; Anisenia, I I

    1992-01-01

    Intraoperative irradiation of tumor was performed in 40 patients with cancer of the lung, stomach, breast, bone and soft tissues. It included irradiation of the bed of tumor removed. Fast electron beam was produced by a small betatron (collimator size--5 x 6 cm and 8 x 12 cm) installed in the operating room. Radiation was given to a single or to multiple fields in a single dose of 10-20 Gy to each field. Location of the radioactive source in the operating room proved technically, economically and medically advantageous since it was cheaper, assured a shorter period of the treatment and delivered from patient transportation to a radiotherapy department and ensuing complications. The procedure did not interfere with postoperative period. The efficacy of the treatment modality will be evaluated as soon as sufficient end results have been obtained.

  7. An Overview of Irradiation Creep of Stainless Steels

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Woo Seog [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    This paper reviewed systematically a state-of-art of irradiation creep for stainless steels to provide a background information for performing irradiation creep tests and establishing the creep model for advanced domestic steels effectively. An irradiation creep model of SFR core materials is necessary to apply to the fuel cladding and assembly materials of domestic SFR reactor system. The document of in-reactor irradiation creep has been obtained by investing a long time and large-scale cost using limited experimental research reactors. This paper will provide the knowledge to understand the irradiation creep and to obtain the background information of advanced domestic steels, so that it hopes to practically apply for timely producing the documents of irradiation creep of advanced domestic steels necessary for the national SFR program.

  8. A Practical Irradiance Model for Bifacial PV Modules

    Energy Technology Data Exchange (ETDEWEB)

    Marion, Bill; MacAlpine, Sara; Deline, Chris; Asgharzadeh, Amir; Toor, Fatima; Riley, Daniel; Stein, Joshua; Hansen, Clifford

    2017-06-21

    A model, suitable for a row or multiple rows of photovoltaic (PV) modules, is presented for estimating the backside irradiance for bifacial PV modules. The model, which includes the effects of shading by the PV rows, is based on the use of configuration factors to determine the fraction of a source of irradiance that is received by the backside of the PV module. Backside irradiances are modeled along the sloped height of the PV module, but assumed not to vary along the length of the PV row. The backside irradiances are corrected for angle-of-incidence losses and may be added to the front side irradiance to determine the total irradiance resource for the PV cell. Model results are compared with the measured backside irradiances for NREL and Sandia PV systems, and with results when using ray tracing software.

  9. Beneficial uses of nuclear byproducts/sewage sludge irradiation project. Progress report, October 1982-March 1983

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, J.D.

    1984-11-01

    Gamma irradiation of various commodities in the Sandia Irradiator for Dried Sewage Solids (SIDSS) and the Gamma Irradiation Facility (GIF) continued during this reporting period. One truck-load of grapefruit was irradiated. Pelletized straw was irradiated to doses of 1, 5, 10, 20, and 40 megarads in SIDSS. Sludge, virus, and fungus samples were irradiated. Infected ground pork and infected pig carcasses were irradiated in the GIF as a method of Trichinella spiralis inactivation. Other experiments conducted in the GIF included irradiation of cut flowers to extend their shelf life and irradiation of kepone to induce its degradation. Waste Encapsulation and Storage Facility (WESF) capsule studies at ORNL and SNLA continued. A purchase order was placed for a prototype sludge solar dryer. Sewage Sludge Irradiation Transportation System (SSITS) cask activities included thermal stress analyses of cask performance following separation from the impact limiters during a fire. Analyses of cask performance, when loaded with six strontium-90 (Sr-90) capsules, also were done.

  10. MELT WIRE SENSORS AVAILABLE TO DETERMINE PEAK TEMPERATURES IN ATR IRRADIATION TESTING

    Energy Technology Data Exchange (ETDEWEB)

    K. L. Davis; D. Knudson; J. Daw; J. Palmer; J. L. Rempe

    2012-07-01

    In April 2007, the Department of Energy (DOE) designated the Advanced Test Reactor (ATR) a National Scientific User Facility (NSUF) to advance US leadership in nuclear science and technology. By attracting new users from universities, laboratories, and industry, the ATR will support basic and applied nuclear research and development and help address the nation's energy security needs. In support of this new program, the Idaho National Laboratory (INL) has developed in-house capabilities to fabricate, test, and qualify new and enhanced temperature sensors for irradiation testing. Although most efforts emphasize sensors capable of providing real-time data, selected tasks have been completed to enhance sensors provided in irradiation locations where instrumentation leads cannot be included, such as drop-in capsule and Hydraulic Shuttle Irradiation System (HSIS) or 'rabbit' locations. To meet the need for these locations, the INL has developed melt wire temperature sensors for use in ATR irradiation testing. Differential scanning calorimetry and environmental testing of prototypical sensors was used to develop a library of 28 melt wire materials, capable of detecting peak irradiation temperatures ranging from 85 to 1500°C. This paper will discuss the development work and present test results.

  11. AGC-2 Irradiation Report

    Energy Technology Data Exchange (ETDEWEB)

    Rohrbaugh, David Thomas [Idaho National Lab. (INL), Idaho Falls, ID (United States); Windes, William [Idaho National Lab. (INL), Idaho Falls, ID (United States); Swank, W. David [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-06-01

    The Next Generation Nuclear Plant (NGNP) will be a helium-cooled, very high temperature reactor (VHTR) with a large graphite core. In past applications, graphite has been used effectively as a structural and moderator material in both research and commercial high temperature gas cooled reactor (HTGR) designs.[ , ] Nuclear graphite H 451, used previously in the United States for nuclear reactor graphite components, is no longer available. New nuclear graphites have been developed and are considered suitable candidates for the new NGNP reactor design. To support the design and licensing of NGNP core components within a commercial reactor, a complete properties database must be developed for these current grades of graphite. Quantitative data on in service material performance are required for the physical, mechanical, and thermal properties of each graphite grade with a specific emphasis on data related to the life limiting effects of irradiation creep on key physical properties of the NGNP candidate graphites. Based on experience with previous graphite core components, the phenomenon of irradiation induced creep within the graphite has been shown to be critical to the total useful lifetime of graphite components. Irradiation induced creep occurs under the simultaneous application of high temperatures, neutron irradiation, and applied stresses within the graphite components. Significant internal stresses within the graphite components can result from a second phenomenon—irradiation induced dimensional change. In this case, the graphite physically changes i.e., first shrinking and then expanding with increasing neutron dose. This disparity in material volume change can induce significant internal stresses within graphite components. Irradiation induced creep relaxes these large internal stresses, thus reducing the risk of crack formation and component failure. Obviously, higher irradiation creep levels tend to relieve more internal stress, thus allowing the

  12. Thermal conductivity of electron-irradiated graphene

    Science.gov (United States)

    Weerasinghe, Asanka; Ramasubramaniam, Ashwin; Maroudas, Dimitrios

    2017-10-01

    We report results of a systematic analysis of thermal transport in electron-irradiated, including irradiation-induced amorphous, graphene sheets based on nonequilibrium molecular-dynamics simulations. We focus on the dependence of the thermal conductivity, k, of the irradiated graphene sheets on the inserted irradiation defect density, c, as well as the extent of defect passivation with hydrogen atoms. While the thermal conductivity of irradiated graphene decreases precipitously from that of pristine graphene, k0, upon introducing a low vacancy concentration, c graphene lattice, further reduction of the thermal conductivity with the increasing vacancy concentration exhibits a weaker dependence on c until the amorphization threshold. Beyond the onset of amorphization, the dependence of thermal conductivity on the vacancy concentration becomes significantly weaker, and k practically reaches a plateau value. Throughout the range of c and at all hydrogenation levels examined, the correlation k = k0(1 + αc)-1 gives an excellent description of the simulation results. The value of the coefficient α captures the overall strength of the numerous phonon scattering centers in the irradiated graphene sheets, which include monovacancies, vacancy clusters, carbon ring reconstructions, disorder, and a rough nonplanar sheet morphology. Hydrogen passivation increases the value of α, but the effect becomes very minor beyond the amorphization threshold.

  13. Modeling precipitate evolution in zirconium alloys during irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Robson, J.D., E-mail: joseph.robson@manchester.ac.uk

    2016-08-01

    The second phase precipitates (SPPs) in zirconium alloys are critical in controlling their performance. During service, SPPs are subject to both thermal and irradiation effects that influence volume fraction, number, and size. In this paper, a model has been developed to capture the combined effect of thermal and irradiation exposure on the Zr(Fe,Cr){sub 2} precipitates in Zircaloy. The model includes irradiation induced precipitate destabilization integrated into a classical size class model for nucleation, growth and coarsening. The model has been applied to predict the effect of temperature and irradiation on SPP evolution. Increasing irradiation displacement rate is predicted to strongly enhance the loss of particles that arises from coarsening alone. The effect of temperature is complex due to competition between coarsening and irradiation damage. As temperature increases, coarsening is predicted to become increasingly important compared to irradiation induced dissolution and may increase resistance to irradiation induced dissolution by increasing particle size. - Highlights: • Model developed to predict effect of thermal and irradiation exposure on precipitates in zirconium alloys. • Model applied to predict effect of changing irradiation dose rate and temperature on precipitates in Zircaloy-4. • Model reveals competition between thermal coarsening and irradiation-induced dissolution. • Model identifies important areas for further study to understand re-precipitation of precipitates after dissolution.

  14. AGR-2 Irradiation Test Final As-Run Report, Rev 2

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-08-01

    This document presents the as-run analysis of the AGR-2 irradiation experiment. AGR-2 is the second of the planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the U.S. Department of Energy as part of the Very High Temperature Reactor (VHTR) Technical Development Office (TDO) program. The objectives of the AGR-2 experiment are to: (a) Irradiate UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Fuel attributes are based on results obtained from the AGR-1 test and other project activities. (b) Provide irradiated fuel samples for post-irradiation experiment (PIE) and safety testing. (c) Support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. The primary objective of the test was to irradiate both UCO and UO2 TRISO (tri-structural isotropic) fuel produced from prototypic scale equipment to obtain normal operation and accident condition fuel performance data. The UCO compacts were subjected to a range of burnups and temperatures typical of anticipated prismatic reactor service conditions in three capsules. The test train also includes compacts containing UO2 particles produced independently by the United States, South Africa, and France in three separate capsules. The range of burnups and temperatures in these capsules were typical of anticipated pebble bed reactor service conditions. The results discussed in this report pertain only to U.S. produced fuel. In order to achieve the test objectives, the AGR-2 experiment was irradiated in the B-12 position of the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL) for a total irradiation duration of 559.2 effective full power days (EFPD). Irradiation began on June 22, 2010, and ended on October 16, 2013, spanning 12 ATR power cycles and approximately three and a

  15. AGR-5/6/7 Irradiation Test Predictions using PARFUME

    Energy Technology Data Exchange (ETDEWEB)

    Skerjanc, William F. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-09-14

    PARFUME, (PARticle FUel ModEl) a fuel performance modeling code used for high temperature gas-cooled reactors (HTGRs), was used to model the Advanced Gas Reactor (AGR)-5/6/7 irradiation test using predicted physics and thermal hydraulics data. The AGR-5/6/7 test consists of the combined fifth, sixth, and seventh planned irradiations of the AGR Fuel Development and Qualification Program. The AGR-5/6/7 test train is a multi-capsule, instrumented experiment that is designed for irradiation in the 133.4-mm diameter north east flux trap (NEFT) position of Advanced Test Reactor (ATR). Each capsule contains compacts filled with uranium oxycarbide (UCO) unaltered fuel particles. This report documents the calculations performed to predict the failure probability of tristructural isotropic (TRISO)-coated fuel particles during the AGR-5/6/7 experiment. In addition, this report documents the calculated source term from the driver fuel. The calculations include modeling of the AGR-5/6/7 irradiation that is scheduled to occur from October 2017 to April 2021 over a total of 13 ATR cycles, including nine normal cycles and four Power Axial Locator Mechanism (PALM) cycle for a total between 500 – 550 effective full power days (EFPD). The irradiation conditions and material properties of the AGR-5/6/7 test predicted zero fuel particle failures in Capsules 1, 2, and 4. Fuel particle failures were predicted in Capsule 3 due to internal particle pressure. These failures were predicted in the highest temperature compacts. Capsule 5 fuel particle failures were due to inner pyrolytic carbon (IPyC) cracking causing localized stresses concentrations in the SiC layer. This capsule predicted the highest particle failures due to the lower irradiation temperature. In addition, shrinkage of the buffer and IPyC layer during irradiation resulted in formation of a buffer-IPyC gap. The two capsules at the two ends of the test train, Capsules 1 and 5 experienced the smallest buffer-IPyC gap

  16. Triple ion beam irradiation facility

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, M.B.; Allen, W.R.; Buhl, R.A.; Packan, N.H.; Cook, S.W.; Mansur, L.K.

    1988-12-01

    A unique ion irradiation facility consisting of three accelerators is described. The accelerators can be operated simultaneously to deliver three ion beams on one target sample. The energy ranges of the ions are 50 to 400 keV, 200 keV to 2.5 MeV, and 1.0 to 5.0 MeV. Three different ions in the appropriate mass range can be simultaneously implanted to the same depth in a target specimen as large as 100 mm/sup 2/ in area. Typical depth ranges are 0.1 to 1.0 ..mu..m. The X-Y profiles of all three ion beams are measured by a system of miniature Faraday cups. The low-voltage accelerator can periodically ramp the ion beam energy during the implantation. Three different types of target chambers are in use at this facility. The triple-beam high-vacuum chamber can hold nine transmission electron microscopy specimens at elevated temperature during a irradiation by the three simultaneous beams. A second high-vacuum chamber on the medium-voltage accelerator beamline houses a low- and high-temperature translator and a two-axis goniometer for ion channeling measurements. The third chamber on the high-energy beamline can be gas-filled for special stressed specimen irradiations. Special applications for the surface modification of materials with this facility are described. Appendixes containing operating procedures are also included. 18 refs., 27 figs., 1 tab.

  17. Implant therapy in irradiated patients.

    Science.gov (United States)

    Sammartino, Gilberto; Marenzi, Gaetano; Cioffi, Iacopo; Teté, Stefano; Mortellaro, Carmen

    2011-03-01

    In this multicenter study, submerged implants were prospectively followed to evaluate their long-term prognosis in irradiated patients. In a total of 77 patients treated for oral or neck cancer, 188 implants were consecutively placed. After a healing period, the successfully integrated implants were restored with 69 removable and 38 fixed restorations. The implants cumulative survival and success rates were evaluated over a period of at least 36 months. In addition, cumulative success rates were calculated for implant subgroups divided per implant site (mandible or maxilla), radiation dosage, and the time interval between the last irradiation and implant placement. During the healing period, 20 implants did not successfully integrate, whereas 168 implants were classified as success (including both survival and success rates). The analysis of implant subgroups showed slightly more favorable cumulative success rate for mandibular implants (98.4%) compared with maxillary implants (57.1%) and clearly better success rate for a radiation dosage minor of 50-Gy doses. A time greater than 12 months as interval between last irradiation and implant placement seems not to promote better clinical results.

  18. Submission of FeCrAl Feedstock for Support of AFC ATR-2 Irradiations

    Energy Technology Data Exchange (ETDEWEB)

    Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Barrett, Kristine E. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Sun, Zhiqian [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Yamamoto, Yukinori [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-09-16

    The Advanced Test Reactor (ATR) is currently being used to test accident tolerant fuel (ATF) forms destined for commercial nuclear power plant deployment. One irradiation program using the ATR for ATF concepts, Accident Tolerant Fuel-2 (ATF-2), is a water loop irradiation test using miniaturized fuel pins as test articles. This complicated testing configuration requires a series of pre-test experiments and verification including a flowing loop autoclave test and a sensor qualification test (SQT) prior to full test train deployment within the ATR. In support of the ATF-2 irradiation program, Oak Ridge National Laboratory (ORNL) has supplied two different Generation II FeCrAl alloys in rod stock form to Idaho National Laboratory (INL). These rods will be machined into dummy pins for deployment in the autoclave test and SQT. Post-test analysis of the dummy pins will provide initial insight into the performance of Generation II FeCrAl alloys in the ATF-2 irradiation experiment as well as within a commercial nuclear reactor.

  19. A Solar Irradiance Climate Data Record

    Science.gov (United States)

    Coddington, O.; Lean, J. L.; Pilewskie, P.; Snow, M.; Lindholm, D.

    2016-08-01

    We present a new climate data record for total solar irradiance and solar spectral irradiance between 1610 and the present day with associated wavelength and time-dependent uncertainties and quarterly updates. The data record, which is part of the National Oceanic and Atmospheric Administration’s (NOAA) Climate Data Record (CDR) program, provides a robust, sustainable, and scientifically defensible record of solar irradiance that is of sufficient length, consistency, and continuity for use in studies of climate variability and climate change on multiple time scales and for user groups spanning climate modeling, remote sensing, and natural resource and renewable energy industries. The data record, jointly developed by the University of Colorado’s Laboratory for Atmospheric and Space Physics (LASP) and the Naval Research Laboratory (NRL), is constructed from solar irradiance models that determine the changes with respect to quiet sun conditions when facular brightening and sunspot darkening features are present on the solar disk where the magnitude of the changes in irradiance are determined from the linear regression of a proxy magnesium (Mg) II index and sunspot area indices against the approximately decade-long solar irradiance measurements of the Solar Radiation and Climate Experiment (SORCE). To promote long-term data usage and sharing for a broad range of users, the source code, the dataset itself, and supporting documentation are archived at NOAA's National Centers for Environmental Information (NCEI). In the future, the dataset will also be available through the LASP Interactive Solar Irradiance Data Center (LISIRD) for user-specified time periods and spectral ranges of interest.

  20. Helium irradiation induced hardening in MNHS steels

    Science.gov (United States)

    Cui, Minghuan; Wang, Ji; Wang, Zhiguang; Shen, Tielong; Wei, Kongfang; Yao, Cunfeng; Sun, Jianrong; Gao, Ning; Zhu, Yabin; Pang, Lilong; Wang, Dong; Zhu, Huiping; Han, Yi; Fang, Xuesong

    2017-09-01

    A recently developed reduced activation martensitic MNHS steel was irradiated with 200 keV helium (He) ions to a fluence of 1.0 × 1020 ions/m2 at 300 °C and 1.0 × 1021 ions/m2 at 300 °C and 450 °C. After irradiation, transmission electron microscopy (TEM) and nano-indentation measurements were used to investigate the hardness change and defects induced by He irradiation. Two kinds of defects including He bubbles and dislocation loops are observed by TEM. Irradiation induces hardening of MNHS steels and peak hardness values occur in all irradiated samples. Hardness increments induced by He bubbles and dislocation loops are predicted and fitted with the experimental peak hardness increment, based on the dispersed barrier-hardening (DBH) model and the size and number density of the two defects. A good agreement is got between the predicted and experimental hardness increment and the obstacle strength factor of He bubbles is a little stronger than the obstacle strength of dislocation loops. Other possible contributions to irradiation induced hardening are also discussed.

  1. SCK-CEN Contribution to the IAEA Round Robin Exercise on WWER-440 RPV Weld Material Irradiation, Annealing and Re-Embrittlement

    Energy Technology Data Exchange (ETDEWEB)

    Van Walle, E.; Chaouadi, R.; Puzzolante, J.L.; Fabry, A.; Van de Velde, J

    1998-05-04

    The contribution of the Belgian Nuclear Research Centre SCK-CEN to the IAEA Round Robin Exercise on WWER-440 RPV weld material is reported. The objective of this contribution is twofold: (1) to gain experience in the field of the testing of WWER-440 steels; (2) to analyse the round-robin data according to in-house developed on used models in order to check their validity and applicability. Results from testing on unirradiated material are reported including data obtained from chemical analysis, Charpy-V impact testing, tensile testing and fracture toughness determination. Finally, irradiation strategies that can be used in the program to obtain irradiated, irradiated-annealed and irradiated-annealed-reirradiated conditions are outlined.

  2. BNCT irradiation facility at the JRR-4

    Energy Technology Data Exchange (ETDEWEB)

    Torii, Y.; Kishi, T.; Kumada, H.; Yamamoto, K.; Sakurai, F.; Takayanagi, M. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2000-10-01

    The JRR--4 was modified for fuel enrichment reducing and reactor equipment renewal. And also a medical irradiation facility for the Boron Neutron Capture Therapy (BNCT) was installed at the JRR--4 in that time. The medical irradiation facility has been composed of a heavy water tank, a collimator and an irradiation room. The heavy water tank has four layers of heavy water for spectrum shifter and 75cm-thickness aluminum for the shield of fast neutron. The collimator is for collimating thermal neutron and epithermal neutron using polyethylene with lithium-fluoride and shielding gamma ray by bismuth. The irradiation room has sufficient space at exit side of the beam, to accommodate a large working area for setting the patient. Both of the medical treatment room and the patient-monitoring area were prepared adjacent to the irradiation room. The medical irradiation facility in the JRR-4 is designed to permit selection of neutron energies from thermal neutron to epithermal neutron by changing the thickness of heavy water layers. Therefore it is available to continue the same kind of BNCT with thermal neutron used to perform in the JRR-2, as well as to commence the research and development of BNCT with epithermal neutron, which will make the brain tumor treatment possible at a deep part of brain. The full power operation of the JRR-4 was resumed with LEU fuel in October 1998 and currently performing some experiments to measure the neutron fluxes and physical doses for determinate characterization of the medical irradiation facility. The first medical irradiation for BNCT was carried out on 25th October 1999. The patient was treated by Tsukuba University group using thermal neutron beam included epi-thermal neutrons. (author)

  3. The Birmingham Irradiation Facility

    CERN Document Server

    Dervan, P; Hodgson, P; Marin-Reyes, H; Wilson, J

    2013-01-01

    At the end of 2012 the proton irradiation facility at the CERN PS [1] will shut down for two years. With this in mind, we have been developing a new ATLAS scanning facility at the University of Birmingham Medical Physics cyclotron. With proton beams of energy approximately 30 MeV, fluences corresponding to those of the upgraded Large Hadron Collider (HL-LHC) can be reached conveniently. The facility can be used to irradiate silicon sensors, optical components and mechanical structures (e.g. carbon fibre sandwiches) for the LHC upgrade programme. Irradiations of silicon sensors can be carried out in a temperature controlled cold box that can be scanned through the beam. The facility is described in detail along with the first tests carried out with mini (1 x 1 cm^2 ) silicon sensors.

  4. Food irradiation: technology transfer in Asia, practical experiences

    Energy Technology Data Exchange (ETDEWEB)

    Kunstadt, P. (Nordion International Inc., Kanata, ON (Canada))

    Nordion International Inc., in cooperation with the Thai Office of Atomic Energy for Peace (OAEP) and the Canadian International Development Agency (CIDA) recently completed a unique food irradiation technology transfer project in Thailand. This complete food irradiation technology transfer project included the design and construction of an automatic multipurpose irradiation facility as well as the services of construction and installation management and experts in facility operation, maintenance and training. This paper provides an insight into the many events that led to the successful conclusion of the world's first complete food irradiation technology transfer project. (Author).

  5. Food irradiation: Technology transfer in Asia, practical experiences

    Science.gov (United States)

    Kunstadt, Peter; Eng, P.

    1993-10-01

    Nordion International Inc., in cooperation with the Thai Office of Atomic Energy for Peace (OAEP) and the Canadian International Development Agency (CIDA) recently completed a unique food irradiation technology transfer project in Thailand. This complete food irradiation technology transfer project included the design and construction of an automatic multipurpose irradiation facility as well as the services of construction and installation management and experts in facility operation, maintenance and training. This paper provides an insight into the many events that led to the succesful conclusion of the world's first complete food irradiation technology transfer project.

  6. Horizontal modular dry irradiated fuel storage system

    Science.gov (United States)

    Fischer, Larry E.; McInnes, Ian D.; Massey, John V.

    1988-01-01

    A horizontal, modular, dry, irradiated fuel storage system (10) includes a thin-walled canister (12) for containing irradiated fuel assemblies (20), which canister (12) can be positioned in a transfer cask (14) and transported in a horizontal manner from a fuel storage pool (18), to an intermediate-term storage facility. The storage system (10) includes a plurality of dry storage modules (26) which accept the canister (12) from the transfer cask (14) and provide for appropriate shielding about the canister (12). Each module (26) also provides for air cooling of the canister (12) to remove the decay heat of the irradiated fuel assemblies (20). The modules (26) can be interlocked so that each module (26) gains additional shielding from the next adjacent module (26). Hydraulic rams (30) are provided for inserting and removing the canisters (12) from the modules (26).

  7. [Improved program maintenance of the CIRCIS dosimetric planning system].

    Science.gov (United States)

    Sevast'ianov, A I; Liutova, N A; Ratner, T G

    1983-03-01

    A special computer complex CIRCIS (Informatique, France) is used in the All-Union Cancer Research Center, USSR AMS, for the dosimetric planning of radiotherapy on 5 gamma-beam units and electron accelerator. Mathematical maintenance of the complex includes programs of the calculation of dose distribution for gamma-, inhibition and electron radiation but has no program of the calculation of the time of irradiation. The authors have devised and introduced into the complex such a program in the Fortran language that makes it possible to calculate within 2-3 min the time of irradiation for multifield rotation therapy using several units as a time, thus expediting the dosimetric planning for patients' irradiation.

  8. Fabrication Control Plan for ORNL RH-LOCA ATF Test Specimens to be Irradiated in the ATR

    Energy Technology Data Exchange (ETDEWEB)

    Field, Kevin G. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Howard, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States); Teague, Michael [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-06-01

    The purpose of this fabrication plan is (1) to summarize the design of a set of rodlets that will be fabricated and then irradiated in the Advanced Test Reactor (ATR) and (2) provide requirements for fabrication and acceptance criteria for inspections of the Light Water Reactor (LWR) – Accident Tolerant Fuels (ATF) rodlet components. The functional and operational (F&OR) requirements for the ATF program are identified in the ATF Test Plan. The scope of this document only covers fabrication and inspections of rodlet components detailed in drawings 604496 and 604497. It does not cover the assembly of these items to form a completed test irradiation assembly or the inspection of the final assembly, which will be included in a separate INL final test assembly specification/inspection document. The controls support the requirements that the test irradiations must be performed safely and that subsequent examinations must provide valid results.

  9. The role of local irradiation for advanced neuroblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Masunaga, Ken; Mugishima, Hideo; Harada, Kensuke [Nihon Univ., Tokyo (Japan). School of Medicine

    1995-06-01

    Since 1985, 30 patients with advanced neuroblastoma were treated with a comprehensive therapy including chemotherapy, radiotherapy, operation, and autologous bone marrow transplant (A-BMT). After surgery, many patients received local irradiation at the primary tumor site. We investigated the role of local irradiation for advanced neuroblastoma. Of the 30 patients, 22 received local irradiation. These patients included 2 with stage III, 17 with stage IV{sub A}, and 3 with stage IV{sub B}. Most patients were 1 year of age or older at the time of diagnosis. Adrenal tumors were present in 13, retroperitoneal in 5, thoracic in 3, and both retroperitoneal and thoracic in 1. N-myc amplification was present in 8 patients. In terms of patient characteristics, there were no difference between local irradiation group and non-local irradiation group. All patients received induction chemotherapy, as described by Sawaguchi and others. After surgery, 22 patients received local irradiation of 10 to 26 Gy in 1 to 16 fractions at the primary tumor site. Intraoperative irradiation in a dose of 10 to 15 Gy in single fraction had been administered to 15 patients. Most patients received purged marrow using immunomagnetic beads. All patients received preconditioning regimen (VAMP, modified VAMP with or without TBI) and then transplanted. Following A-BMT, 13-cis-retinoic acid was administered for the purpose of tumor differentiation. Of the 22 patients with local irradiation, 6 relapsed and 5 died. Of the 8 patients without local irradiation, 2 relapsed and 1 died. Patients who completely received local irradiation showed no evidence of primary tumor recurrence. Patients who did not receive or incompletely received local irradiation showed primary tumor recurrence. Local irradiation for advanced neuroblastoma is very useful treatment to prevent primary tumor recurrence. (author).

  10. Radiation-disorder and aperiodicity in irradiated ceramics. Final technical report, 22 June 1989--21 June 1992

    Energy Technology Data Exchange (ETDEWEB)

    Hobbs, L.W.

    1992-07-01

    This final technical report documents the accomplishments of the program of research entitled ``Radiation Disorder and Aperiodicity in Irradiated Ceramics`` for the period June 22, 1989--June 21, 1992. This research forms the latest part on an on-going program, begun at MIT in 1983 under DOE support, which has had as its objectives investigation of the responses in radiation environments of ceramics heavily-irradiated with electrons, neutrons and ions, with potential applications to fusion energy technology and high-level nuclear waste storage. Materials investigated have included SiO{sub 2}, MgAl{sub 2}O{sub 4}, Al{sub 23}O{sub 27}N{sub 5}, SiC, BeO, LiAlO{sub 2}, Li{sub 2}ZrO{sub 3}, CaTiO{sub 3}KTaO{sub 3} and Ca(Zr, Pu)Ti{sub 2}O{sub 7}. The program initially proposed for 1989 had as its major objectives two main thrusts: (1) research on defect aggregation in irradiated non-oxide ceramics, and (2) research on irradiation-induced amorphization of network silicas and phosphates.

  11. Childhood Head and Neck Irradiation

    Science.gov (United States)

    ... Thyroid Association ® www.thyroid.org Childhood Head & Neck Irradiation What is the thyroid gland? The thyroid gland ... Thyroid Association ® www.thyroid.org Childhood Head & Neck Irradiation Thyroid nodules (see Thyroid Nodule brochure) • Thyroid nodules ...

  12. Tensile properties of CLAM steel irradiated up to 20.1 dpa in STIP-V

    Science.gov (United States)

    Ge, Hongen; Peng, Lei; Dai, Yong; Huang, Qunying; Ye, Minyou

    2016-01-01

    Specimens of China low activation martensitic steel (CLAM) were irradiated in the fifth experiment of SINQ Target Irradiation Program (STIP-V) up to 20.1 dpa/1499 appm He/440 °C. Tensile tests were performed at room temperature (R.T) and irradiation temperatures (Tirr) in the range of 25-450 °C. The tensile results demonstrated strong effect of irradiation dose and irradiation temperature on hardening and embrittlement. With Tirr below ˜314 °C, CLAM steel specimens tested at R.T and Tirr showed similar evolution trend with irradiation dose, compared to other reduced activation ferritic/martensitic (RAFM) steels in similar irradiation conditions. At higher Tirr above ˜314 °C, it is interesting that the hardening effect decreases and the ductility seems to recover, probably due to a strong effect of high irradiation temperature.

  13. Advanced Reactor Fuels Irradiation Experiment Design Objectives

    Energy Technology Data Exchange (ETDEWEB)

    Chichester, Heather Jean MacLean [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hayes, Steven Lowe [Idaho National Lab. (INL), Idaho Falls, ID (United States); Dempsey, Douglas [Idaho National Lab. (INL), Idaho Falls, ID (United States); Harp, Jason Michael [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    This report summarizes the objectives of the current irradiation testing activities being undertaken by the Advanced Fuels Campaign relative to supporting the development and demonstration of innovative design features for metallic fuels in order to realize reliable performance to ultra-high burnups. The AFC-3 and AFC-4 test series are nearing completion; the experiments in this test series that have been completed or are in progress are reviewed and the objectives and test matrices for the final experiments in these two series are defined. The objectives, testing strategy, and test parameters associated with a future AFC test series, AFC-5, are documented. Finally, the future intersections and/or synergies of the AFC irradiation testing program with those of the TREAT transient testing program, emerging needs of proposed Versatile Test Reactor concepts, and the Joint Fuel Cycle Study program’s Integrated Recycle Test are discussed.

  14. Beneficial uses program. Progress report for period ending March 31, 1977

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-07-01

    Progress is reported in a program aimed at recovering radiation sources from radioactive wastes and using these sources, mainly /sup 137/Cs, for irradiating sewage sludge. Information is included on: development and cost of dried sludge irradiator; heat and radiation inactivation of sludge-contained viruses and bacteria; virucidal agents in sludge; use of thermoradiated sludge as animal feed; and a comparison of the efficiency of various source materials. (LCL)

  15. Capsule Development and Utilization for Material Irradiation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Goo; Kang, Y. H.; Cho, M. S. (and others)

    2007-06-15

    The essential technology for an irradiation test of materials and nuclear fuel has been successively developed and utilized to meet the user's requirements in Phase I(July 21, 1997 to March 31, 2000). It enables irradiation tests to be performed for a non-fissile material under a temperature control(300{+-}10 .deg. C) in a He gas environment, and most of the irradiation tests for the internal and external users are able to be conducted effectively. The basic technology was established to irradiate a nuclear fuel, and a creep capsule was also developed to measure the creep property of a material during an irradiation test in HANARO in Phase II(April 1, 2000 to March 31, 2003). The development of a specific purpose capsule, essential technology for a re-irradiation of a nuclear fuel, advanced technology for an irradiation of materials and a nuclear fuel were performed in Phase III(April 1, 2003 to February 28, 2007). Therefore, the technology for an irradiation test was established to support the irradiation of materials and a nuclear fuel which is required for the National Nuclear R and D Programs. In addition, an improvement of the existing capsule design and fabrication technology, and the development of an instrumented capsule for a nuclear fuel and a specific purpose will be able to satisfy the user's requirements. In order to support the irradiation test of materials and a nuclear fuel for developing the next generation nuclear system, it is also necessary to continuously improve the design and fabrication technology of the existing capsule and the irradiation technology.

  16. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  17. Visual Impairment, Including Blindness

    Science.gov (United States)

    ... Who Knows What? (log-in required) Select Page Visual Impairment, Including Blindness Mar 31, 2017 Links updated, ... doesn’t wear his glasses. Back to top Visual Impairments in Children Vision is one of our ...

  18. AGR-1 Irradiation Test Final As-Run Report, Rev. 3

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-01-01

    This document presents the as-run analysis of the AGR-1 irradiation experiment. AGR-1 is the first of eight planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the US Department of Energy (DOE) as part of the Next-Generation Nuclear Plant (NGNP) project. The objectives of the AGR-1 experiment are: 1. To gain experience with multi-capsule test train design, fabrication, and operation with the intent to reduce the probability of capsule or test train failure in subsequent irradiation tests. 2. To irradiate fuel produced in conjunction with the AGR fuel process development effort. 3. To provide data that will support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. In order to achieve the test objectives, the AGR-1 experiment was irradiated in the B-10 position of the Advanced Test Reactor (ATR) at the Idaho National Laboratory (INL) for a total duration of 620 effective full power days of irradiation. Irradiation began on December 24, 2006 and ended on November 6, 2009 spanning 13 ATR cycles and approximately three calendar years. The test contained six independently controlled and monitored capsules. Each capsule contained 12 compacts of a single type, or variant, of the AGR coated fuel. No fuel particles failed during the AGR-1 irradiation. Final burnup values on a per compact basis ranged from 11.5 to 19.6 %FIMA, while fast fluence values ranged from 2.21 to 4.39 x 1025 n/m2 (E >0.18 MeV). We’ll say something here about temperatures once thermal recalc is done. Thermocouples performed well, failing at a lower rate than expected. At the end of the irradiation, nine of the originally-planned 19 TCs were considered functional. Fission product release-to-birth (R/B) ratios were quite low. In most capsules, R/B values at the end of the irradiation were at or below

  19. Implementation of good manufacturing practices (GMP) on human blood irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Boghi, Claudio; Napolitano, Celia M.; Ferreira, Danilo C.; Rela, Paulo Roberto [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mails: cboghi@uol.com.br; cmnapoli@ipen.br; dancarde@ig.com.br; prela@ipen.br; Zarate, Herman S. [Comission Chilena de Energia Nuclear, Santiago (Chile)]. E-mail: hzarate@cchen.cl

    2007-07-01

    The irradiation of human blood is used to avoid the TA-GVHD (transfusion-associated graft-versus-host-disease), a rare but devastating adverse effect of leukocytes present in blood components for a immuno-competent transfusion recipients. Usually this irradiation practice is performed to a physical elimination of lymphocytes. The implementation of the GMP will assure that the properly dose in a range of 25 Gy to 50 Gy will be delivered to the blood in the bag collected in a blood tissue bank. The studies to establish the GMP were developed under the guidelines of the standard ISO 11137 - Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. In this work, two dosimetric systems were used for dose mapping during the studies of irradiator qualification, loading pattern, irradiation process validation and auditing. The CaSO{sub 4}: Dy dosimeter presented difficulties concerning to uncertainty on dose measurement, stability, trace ability and calibration system. The PMMA and gafchromic dosimetric systems have shown a better performance and were adopted on establishment of GMP procedures. The irradiation tests have been done using a Gammacell 220 Irradiator. The developed GMP can be adapted for different types of gamma irradiators, allowing to set up a quality assurance program for blood irradiation. (author)

  20. Irradiation of Wrought FeCrAl Tubes in the High Flux Isotope Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Linton, Kory D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Petrie, Christian M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-09-01

    The Advanced Fuels Campaign within the Nuclear Technology Research and Development program of the Department of Energy Office of Nuclear Energy is seeking to improve the accident tolerance of light water reactors. Alumina-forming ferritic alloys (e.g., FeCrAl) are one of the leading candidate materials for fuel cladding to replace traditional zirconium alloys because of the superior oxidation resistance of FeCrAl. However, there are still some unresolved questions regarding irradiation effects on the microstructure and mechanical properties of FeCrAl at end-of-life dose levels. In particular, there are concerns related to irradiation-induced embrittlement of FeCrAl alloys due to secondary phase formation. To address this issue, Oak Ridge National Laboratory has developed a new experimental design to irradiate shortened cladding tube specimens with representative 17×17 array pressurized water reactor diameter and thickness in the High Flux Isotope Reactor (HFIR) under relevant temperatures (300–350°C). Post-irradiation examination will include studies of dimensional change, microstructural changes, and mechanical performance. This report briefly summarizes the capsule design concept and the irradiation test matrix for six rabbit capsules. Each rabbit contains two FeCrAl alloy tube specimens. The specimens include Generation I and Generation II FeCrAl alloys with varying processing conditions, Cr concentrations, and minor alloying elements. The rabbits were successfully assembled, welded, evaluated, and delivered to the HFIR along with a complete quality assurance fabrication package. Pictures of the rabbit assembly process and detailed dimensional inspection of select specimens are included in this report. The rabbits were inserted into HFIR starting in cycle 472 (May 2017).

  1. Infrared Irradiation: Toward Green Chemistry, a Review

    Directory of Open Access Journals (Sweden)

    René Escobedo

    2016-03-01

    Full Text Available This review provides a comprehensive overview of where infrared irradiation has been employed, mainly as regards activating green mode for natural products extractions, as well as to favor a reaction, highlighting its actual importance. It is also underlined that infrared irradiation heating has been around for a long time; however, only in the last eighteen years have many of its advantages been applied to satisfy a wide range of chemical processes, natural products extractions, and for the promotion of many kinds of reactions. In addition, it is brought to light that near infrared irradiation is more efficient than middle and far infrared irradiations, being easily controllable and with the quality of a fast responding heat source. Thus, the main objective of this review is to offer infrared irradiation as an alternative clean energy source to activate reactions, in addition to favor the selective extraction of natural products, all of which is within the Green Chemistry protocol. Some recent results from our laboratory are also included.

  2. Infrared Irradiation: Toward Green Chemistry, a Review.

    Science.gov (United States)

    Escobedo, René; Miranda, René; Martínez, Joel

    2016-03-26

    This review provides a comprehensive overview of where infrared irradiation has been employed, mainly as regards activating green mode for natural products extractions, as well as to favor a reaction, highlighting its actual importance. It is also underlined that infrared irradiation heating has been around for a long time; however, only in the last eighteen years have many of its advantages been applied to satisfy a wide range of chemical processes, natural products extractions, and for the promotion of many kinds of reactions. In addition, it is brought to light that near infrared irradiation is more efficient than middle and far infrared irradiations, being easily controllable and with the quality of a fast responding heat source. Thus, the main objective of this review is to offer infrared irradiation as an alternative clean energy source to activate reactions, in addition to favor the selective extraction of natural products, all of which is within the Green Chemistry protocol. Some recent results from our laboratory are also included.

  3. Irradiation Processing Department monthly report, October 1963

    Energy Technology Data Exchange (ETDEWEB)

    1963-11-15

    This document details activities of the irradiation processing department during the month of October, 1963. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; and Financial Operation.

  4. Irradiation Processing Department monthly report, April 1963

    Energy Technology Data Exchange (ETDEWEB)

    1963-05-13

    This document details activities of the Irradiation Processing Department during the month of August, 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  5. Irradiation Processing Department monthly report, January 1964

    Energy Technology Data Exchange (ETDEWEB)

    1964-02-14

    This document details activities of the Irradiation Processing Department during the month of August, 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  6. Irradiation Processing Department monthly report, February 1963

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A. B.

    1963-03-14

    This document details activities of the Irradiation Processing Department during the month of August, 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  7. Irradiation Processing Department monthly report, October 1961

    Energy Technology Data Exchange (ETDEWEB)

    1961-11-17

    This document details activities of the irradiation processing department during the month of October, 1961. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  8. Irradiation Processing Department monthly report, March 1961

    Energy Technology Data Exchange (ETDEWEB)

    1961-04-14

    This document details activities of the irradiation processing department during the month of March, 1961. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; Financial Operation; and NPR project.

  9. Irradiation Processing Department monthly report, December 1961

    Energy Technology Data Exchange (ETDEWEB)

    1962-01-15

    This document details activities of the irradiation processing department during the month of December, 1961. Al general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations: Production and reactor Operations; Facilities Engineering Operation; and NPR project.

  10. Irradiation Processing Department monthly report, August 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-09-12

    This document details activities of the irradiation processing department during the month of August, 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor operations; Facilities Engineering operation; Employee Relations Operation; and Financial Operation.

  11. Determinants of skin sensitivity to solar irradiation

    NARCIS (Netherlands)

    Broekmans, W.M.R.; Vink, A.A.; Boelsma, E.; Klöpping-Ketelaars, W.A.A.; Tijburg, L.B.M.; Veer, P. van 't; Poppel, G. van; Kardinaal, A.F.M.

    2003-01-01

    Background: Acute effects of UV irradiation include UV-induced erythema. Sunlight plays an important role in the development of skin cancer. Several predictive factors of UV-induced erythema could also be predictive for skin cancer. Objective: Our objective was to quantitatively assess phenotypical

  12. Irradiation Processing Department monthly report, August 1962

    Energy Technology Data Exchange (ETDEWEB)

    1962-09-14

    This document details activities of the Irradiation Processing Department during the month of August, 1962. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; and NPR Project.

  13. Irradiation Processing Department monthly report, April 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-05-19

    This document details activities of the irradiation processing department during the month of April, 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  14. Irradiation Processing Department monthly report, December 1958

    Energy Technology Data Exchange (ETDEWEB)

    1959-01-21

    This document details activities of the irradiation processing department during the month of December 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering operation; Employee Relations Operation; and Financial Operation.

  15. Irradiation Processing Department monthly report, May 1960

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1960-06-20

    This document details activities of the irradiation processing department during the month of May, 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  16. Irradiation Processing Department monthly report, January 1961

    Energy Technology Data Exchange (ETDEWEB)

    1961-02-15

    This document details activities of the irradiation processing department during the month of January, 1961. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; Financial Operation; and NPR Project.

  17. Irradiation Processing Department monthly report, February 1959

    Energy Technology Data Exchange (ETDEWEB)

    1959-03-20

    This document details activities of the irradiation processing department during the month of February 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  18. Irradiation Processing Department monthly report, April 1961

    Energy Technology Data Exchange (ETDEWEB)

    1961-05-15

    This document details activities of the irradiation processing department during the month of April, 1961. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; Financial Operation; and NPR project.

  19. Irradiation Processing Department monthly report, May 1961

    Energy Technology Data Exchange (ETDEWEB)

    1961-06-15

    This document details activities of the irradiation processing department during the month of May, 1961. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and NPR Reactor.

  20. Irradiation Processing Department monthly report, November 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-12-14

    This document details activities of the irradiation processing department during the month of November, 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operation; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; Financial Operation; and NPR Project.

  1. Irradiation Processing Department monthly report, July 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-08-12

    This document details activities of the irradiation processing department during the month of July, 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  2. Irradiation Processing Department monthly report, September 1961

    Energy Technology Data Exchange (ETDEWEB)

    1961-10-16

    This document details activities of the irradiation processing department during the month of September, 1961. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; and NPR Project.

  3. Irradiation Processing Department monthly report, July 1961

    Energy Technology Data Exchange (ETDEWEB)

    1961-08-14

    This document details activities of the irradiation processing department during the month of July 1961. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; Financial Operation; and NPR Project.

  4. Irradiation Processing Department monthly report, June 1964

    Energy Technology Data Exchange (ETDEWEB)

    1964-07-15

    This document details activities of the Irradiation Processing Department during the month of June, 1964. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  5. Irradiation Processing Department monthly report, January 1962

    Energy Technology Data Exchange (ETDEWEB)

    1962-02-15

    This document details activities of the Irradiation Processing Department during the month of January, 1962. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; and NPR Project.

  6. Health protection and food preservation by gamma irradiation

    Science.gov (United States)

    1976-01-01

    Results of several major studies on food systems for space missions beginning with Apollo 12 through Apollo-Soyuz and investigations of the application of irradiation to food for manned space flight are reported. The study of flight food systems involved the application of radurization (pasteurizing levels) doses of gamma irradiation to flour and bread supplied by Pepperidge Farms in advance of the missions. All flights from Apollo 12 through 17 carried irradiated fresh bread. On Apollo 17, cooperation with Natick Laboratories permitted the introduction of a ham sandwich using irradiated bread and irradiated sterile ham. Investigations centered on irradiated bread were conducted during the course of these missions. Studies were applied to the concept of improving fresh bread from the point of view of mold inhibition. The studies considered how irradiation could best be applied at what levels and on a variety of bread types. Throughout the studies of the application of gamma irradiation the emphasis was placed upon using low levels of irradiation in the pasteurizing or radurizing doses--under a Megarad. The primary goal was to determine if a public health benefit could be demonstrated using radurization along with food preservation and food quality improvements. The public health benefit would be parallel to that of pasteurization of milk as a concept. Publications are included providing the details of these observations, one dealing with the flour characteristics and the other dealing with the influence on fresh bread types. These demonstrate the major findings noted during the period of the studies examining bread.

  7. Development of a portable blood irradiator for potential clinical uses

    Energy Technology Data Exchange (ETDEWEB)

    Hungate, F.P.

    1988-12-01

    This document provides an account of the development of a fully portable blood irradiator and the evaluation of its safety and efficacy when implanted in goats, sheep, a baboon and dogs. The program was initiated because the control of lymphocyte populations by irradiation is a potential method for improving success in organ or tissue transplantation and for treating a variety of blood diseases. 15 refs., 27 figs., 2 tabs.

  8. Status of food irradiation in the world

    Energy Technology Data Exchange (ETDEWEB)

    Kume, Tamikazu [Takasaki Advanced Radiation Research Institute, Japan Atomic Energy Agency (JAEA), Quantum Beam Science Directorate, 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan); Furuta, Masakazu [Graduate School of Science, Osaka Prefecture University, 1-1 Gakuen-cho, Sakai, Osaka 599-8531 (Japan); Todoriki, Setsuko [National Food Research Institute, 2-1-12 Kannonndai, Tsukuba, Ibaraki 305-8642 (Japan); Uenoyama, Naoki [Department of International Cooperation and Industrial Infrastructure Development, Japan Atomic Industrial Forum, Inc., Shimbashi Fuji Bld., 2-1-3, Shimbashi, Minato-ku, Tokyo 105-8605 Japan (Japan); Kobayashi, Yasuhiko [Quantum Beam Science Directorate, Japan Atomic Energy Agency (JAEA), 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan)], E-mail: kobayashi.yasuhiko@jaea.go.jp

    2009-03-15

    The status of food irradiation in the world in 2005 was investigated using published data, a questionnaire survey and direct visits. The results showed that the quantity of irradiated foods in the world in 2005 was 405,000 ton and comprised 1,86,000 ton (46%) for disinfection of spices and dry vegetables, 82,000 ton (20%) for disinfestation of grains and fruits, 32,000 ton (8%) for disinfection of meat and fish, 88,000 ton (22%) for sprout inhibition of garlic and potato, and 17,000 ton (4%) of other food items that included health foods, mushroom, honey, etc. Commercial food irradiation is increasing significantly in Asia, but decreasing in EU.

  9. Statistical analyses of fracture toughness results for two irradiated high-copper welds

    Energy Technology Data Exchange (ETDEWEB)

    Nanstad, R.K.; McCabe, D.E.; Haggag, F.M.; Bowman, K.O.; Downing, D.J.

    1990-01-01

    The objectives of the Heavy-Section Steel Irradiation Program Fifth Irradiation Series were to determine the effects of neutron irradiation on the transition temperature shift and the shape of the K{sub Ic} curve described in Sect. 6 of the ASME Boiler and Pressure Vessel Code. Two submerged-arc welds with copper contents of 0.23 and 0.31% were commercially fabricated in 215-mm-thick plates. Charpy V-notch (CVN) impact, tensile, drop-weight, and compact specimens up to 203.2 mm thick (1T, 2T, 4T, 6T, and 8T C(T)) were tested to provide a large data base for unirradiated material. Similar specimens with compacts up to 4T were irradiated at about 288{degrees}C to a mean fluence of about 1.5 {times} 10{sup 19} neutrons/cm{sup 2} (>1 MeV) in the Oak Ridge Research Reactor. Both linear-elastic and elastic-plastic fracture mechanics methods were used to analyze all cleavage fracture results and local cleavage instabilities (pop-ins). Evaluation of the results showed that the cleavage fracture toughness values determined at initial pop-ins fall within the same scatter band as the values from failed specimens; thus, they were included in the data base for analysis (all data are designated K{sub Jc}).

  10. Listening to Include

    Science.gov (United States)

    Veck, Wayne

    2009-01-01

    This paper attempts to make important connections between listening and inclusive education and the refusal to listen and exclusion. Two lines of argument are advanced. First, if educators and learners are to include each other within their educational institutions as unique individuals, then they will need to listen attentively to each other.…

  11. Safety of irradiated foods

    Energy Technology Data Exchange (ETDEWEB)

    Iwahara, Shigeo (Foods Medicines Safety Center (Japan)); Kobayashi, Kazuo

    1983-01-01

    The safety of 7 irradiated foods (potato, onion, rice, wheat, vienna sausage, fish paste and mandarine orange), in terms of 2-year long-term toxic effect, reproductive physiology and possible teratogenesis, was studied using 3 generations of rats, mice and monkeys. The genetic toxicity was studied by means of various mutagenicity tests. The details of the studies conducted by the authors to date and some overseas data were reported. The available data showed no toxic effect.

  12. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  13. Assembly and Delivery of Rabbit Capsules for Irradiation of Silicon Carbide Cladding Tube Specimens in the High Flux Isotope Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Koyanagi, Takaaki [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Petrie, Christian M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-09-01

    Neutron irradiation of silicon carbide (SiC)-based fuel cladding under a high radial heat flux presents a critical challenge for SiC cladding concepts in light water reactors (LWRs). Fission heating in the fuel provides a high heat flux through the cladding, which, combined with the degraded thermal conductivity of SiC under irradiation, results in a large temperature gradient through the thickness of the cladding. The strong temperature dependence of swelling in SiC creates a complex stress profile in SiCbased cladding tubes as a result of differential swelling. The Nuclear Science User Facilities (NSUF) Program within the US Department of Energy Office of Nuclear Energy is supporting research efforts to improve the scientific understanding of the effects of irradiation on SiC cladding tubes. Ultimately, the results of this project will provide experimental validation of multi-physics models for SiC-based fuel cladding during LWR operation. The first objective of this project is to irradiate tube specimens using a previously developed design that allows for irradiation testing of miniature SiC tube specimens subjected to a high radial heat flux. The previous “rabbit” capsule design uses the gamma heating in the core of the High Flux Isotope Reactor (HFIR) to drive a high heat flux through the cladding tube specimens. A compressible aluminum foil allows for a constant thermal contact conductance between the cladding tubes and the rabbit housing despite swelling of the SiC tubes. To allow separation of the effects of irradiation from those due to differential swelling under a high heat flux, a new design was developed under the NSUF program. This design allows for irradiation of similar SiC cladding tube specimens without a high radial heat flux. This report briefly describes the irradiation experiment design concepts, summarizes the irradiation test matrix, and reports on the successful delivery of six rabbit capsules to the HFIR. Rabbits of both low and high

  14. Thalidomide Ameliorates Inflammation and Vascular Injury but Aggravates Tubular Damage in the Irradiated Mouse Kidney

    NARCIS (Netherlands)

    Scharpfenecker, Marion; Floot, Ben; Russell, Nicola S.; Coppes, Rob P.; Stewart, Fiona A.

    2014-01-01

    Purpose: The late side effects of kidney irradiation include vascular damage and fibrosis, which are promoted by an irradiation-induced inflammatory response. We therefore treated kidney-irradiated mice with the anti-inflammatory and angiogenesis-modulating drug thalidomide in an attempt to prevent

  15. Irradiation effects on fracture toughness of two high-copper submerged-arc welds, HSSI Series 5. Volume 1, Main report and Appendices A, B, C, and D

    Energy Technology Data Exchange (ETDEWEB)

    Nanstad, R.K.; Haggag, F.M.; McCabe, D.E.; Iskander, S.K.; Bowman, K.O. [Oak Ridge National Lab., TN (United States); Menke, B.H. [Materials Engineering Associates, Inc., Lanham, MD (United States)

    1992-10-01

    The Fifth Irradiation Series in the Heavy-Section Steel Irradiation Program obtained a statistically significant fracture toughness data base on two high-copper (0.23 and 0.31 wt %) submerged-arc welds to determine the shift and shape of the K{sub Ic} curve as a consequence of irradiation. Compact specimens with thicknesses to 101.6 mm (4 in) in the irradiated condition and 203.2 mm (8 in) in the unirradiated condition were tested, in addition to Charpy impact, tensile, and drop-weight specimens. Irradiations were conducted at a nominal temperature of 288{degree}C and an average fluence of 1.5 {times} 10{sup 19} neutrons/cm{sup 2} (>l MeV). The Charpy 41-J temperature shifts are about the same as the corresponding drop-weight NDT temperature shifts. The irradiated welds exhibited substantial numbers of cleavage pop-ins. Mean curve fits using two-parameter (with fixed intercept) nonlinear and linearized exponential regression analysis revealed that the fracture toughness 100 MPa{lg_bullet}{radical}m shifts exceeded the Charpy 41-J shifts for both welds. Analyses of curve shape changes indicated decreases in the slopes of the fracture toughness curves, especially for the higher copper weld. Weibull analyses were performed to investigate development of lower bound curves to the data, including the use of a variable K{sub min} parameter which affects the curve shape.

  16. Being Included and Excluded

    DEFF Research Database (Denmark)

    Korzenevica, Marina

    2016-01-01

    Following the civil war of 1996–2006, there was a dramatic increase in the labor mobility of young men and the inclusion of young women in formal education, which led to the transformation of the political landscape of rural Nepal. Mobility and schooling represent a level of prestige that rural...... politics. It analyzes how formal education and mobility either challenge or reinforce traditional gendered norms which dictate a lowly position for young married women in the household and their absence from community politics. The article concludes that women are simultaneously excluded and included from...... people regard as a prerequisite for participating in local community politics. Based on a fieldwork in two villages of Panchthar district in eastern Nepal, this article explores how these changes strengthen or weaken women’s political agency and how this is reflected in their participation in community...

  17. Local foods can meet micronutrient needs for women in urban Burkina Faso, but only if rarely consumed micronutrient-dense foods are included in daily diets: A linear programming exercise.

    Science.gov (United States)

    Arimond, Mary; Vitta, Bineti S; Martin-Prével, Yves; Moursi, Mourad; Dewey, Kathryn G

    2018-01-01

    Women of reproductive age are at nutritional risk due to their need for nutrient-dense diets. Risk is further elevated in resource-poor environments. In one such environment, we evaluated feasibility of meeting micronutrient needs of women of reproductive age using local foods alone or using local foods and supplements, while minimizing cost. Based on dietary recall data from Ouagadougou, we used linear programming to identify the lowest cost options for meeting 10 micronutrient intake recommendations, while also meeting energy needs and following an acceptable macronutrient intake pattern. We modeled scenarios with maximum intake per food item constrained at the 75th percentile of reported intake and also with more liberal maxima based on recommended portions per day, with and without the addition of supplements. Some scenarios allowed only commonly consumed foods (reported on at least 10% of recall days). We modeled separately for pregnant, lactating, and nonpregnant, nonlactating women. With maxima constrained to the 75th percentile, all micronutrient needs could be met with local foods but only when several nutrient-dense but rarely consumed items were included in daily diets. When only commonly consumed foods were allowed, micronutrient needs could not be met without supplements. When larger amounts of common animal-source foods were allowed, all needs could be met for nonpregnant, nonlactating women but not for pregnant or lactating women, without supplements. We conclude that locally available foods could meet micronutrient needs but that to achieve this, strategies would be needed to increase consistent availability in markets, consistent economic access, and demand. © 2017 John Wiley & Sons Ltd.

  18. Reactor Safety Research Programs

    Energy Technology Data Exchange (ETDEWEB)

    Edler, S. K.

    1981-07-01

    This document summarizes the work performed by Pacific Northwest Laboratory (PNL) from January 1 through March 31, 1981, for the Division of Reactor Safety Research within the U.S. Nuclear Regulatory Commission (NRC). Evaluations of nondestructive examination (NDE) techniques and instrumentation are reported; areas of investigation include demonstrating the feasibility of determining the strength of structural graphite, evaluating the feasibility of detecting and analyzing flaw growth in reactor pressure boundary systems, examining NDE reliability and probabilistic fracture mechanics, and assessing the integrity of pressurized water reactor (PWR) steam generator tubes where service-induced degradation has been indicated. Experimental data and analytical models are being provided to aid in decision-making regarding pipeto- pipe impacts following postulated breaks in high-energy fluid system piping. Core thermal models are being developed to provide better digital codes to compute the behavior of full-scale reactor systems under postulated accident conditions. Fuel assemblies and analytical support are being provided for experimental programs at other facilities. These programs include loss-ofcoolant accident (LOCA) simulation tests at the NRU reactor, Chalk River, Canada; fuel rod deformation, severe fuel damage, and postaccident coolability tests for the ESSOR reactor Super Sara Test Program, Ispra, Italy; the instrumented fuel assembly irradiation program at Halden, Norway; and experimental programs at the Power Burst Facility, Idaho National Engineering Laboratory (INEL). These programs will provide data for computer modeling of reactor system and fuel performance during various abnormal operating conditions.

  19. AGR-3/4 Irradiation Test Predictions using PARFUME

    Energy Technology Data Exchange (ETDEWEB)

    Skerjanc, William Frances [Idaho National Lab. (INL), Idaho Falls, ID (United States); Collin, Blaise Paul [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    PARFUME, a fuel performance modeling code used for high temperature gas reactors, was used to model the AGR-3/4 irradiation test using as-run physics and thermal hydraulics data. The AGR-3/4 test is the combined third and fourth planned irradiations of the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. The AGR-3/4 test train consists of twelve separate and independently controlled and monitored capsules. Each capsule contains four compacts filled with both uranium oxycarbide (UCO) unaltered “driver” fuel particles and UCO designed-to-fail (DTF) fuel particles. The DTF fraction was specified to be 1×10-2. This report documents the calculations performed to predict failure probability of TRISO-coated fuel particles during the AGR-3/4 experiment. In addition, this report documents the calculated source term from both the driver fuel and DTF particles. The calculations include the modeling of the AGR-3/4 irradiation that occurred from December 2011 to April 2014 in the Advanced Test Reactor (ATR) over a total of ten ATR cycles including seven normal cycles, one low power cycle, one unplanned outage cycle, and one Power Axial Locator Mechanism cycle. Results show that failure probabilities are predicted to be low, resulting in zero fuel particle failures per capsule. The primary fuel particle failure mechanism occurred as a result of localized stresses induced by the calculated IPyC cracking. Assuming 1,872 driver fuel particles per compact, failure probability calculated by PARFUME leads to no predicted particle failure in the AGR-3/4 driver fuel. In addition, the release fraction of fission products Ag, Cs, and Sr were calculated to vary depending on capsule location and irradiation temperature. The maximum release fraction of Ag occurs in Capsule 7 reaching up to 56% for the driver fuel and 100% for the DTF fuel. The release fraction of the other two fission products, Cs and Sr, are much smaller and in most cases less than 1% for the

  20. CASKS (Computer Analysis of Storage casKS): A microcomputer based analysis system for storage cask design review. User`s manual to Version 1b (including program reference)

    Energy Technology Data Exchange (ETDEWEB)

    Chen, T.F.; Gerhard, M.A.; Trummer, D.J.; Johnson, G.L.; Mok, G.C. [Lawrence Livermore National Lab., CA (United States)

    1995-02-01

    CASKS (Computer Analysis of Storage casKS) is a microcomputer-based system of computer programs and databases developed at the Lawrence Livermore National Laboratory (LLNL) for evaluating safety analysis reports on spent-fuel storage casks. The bulk of the complete program and this user`s manual are based upon the SCANS (Shipping Cask ANalysis System) program previously developed at LLNL. A number of enhancements and improvements were added to the original SCANS program to meet requirements unique to storage casks. CASKS is an easy-to-use system that calculates global response of storage casks to impact loads, pressure loads and thermal conditions. This provides reviewers with a tool for an independent check on analyses submitted by licensees. CASKS is based on microcomputers compatible with the IBM-PC family of computers. The system is composed of a series of menus, input programs, cask analysis programs, and output display programs. All data is entered through fill-in-the-blank input screens that contain descriptive data requests.

  1. Report Summarizing the Effort Required to Initiate Welding of Irradiated Materials within the Welding Cubicle

    Energy Technology Data Exchange (ETDEWEB)

    Frederick, Greg [Electric Power Research Institute (EPRI), Palo Alto, CA (United States); Sutton, Benjamin J. [Electric Power Research Institute (EPRI), Palo Alto, CA (United States); Tatman, Jonathan K. [Electric Power Research Institute (EPRI), Palo Alto, CA (United States); Vance, Mark Christopher [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Smith, Allen W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Clark, Scarlett R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Feng, Zhili [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Miller, Roger G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Chen, Jian [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Tang, Wei [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hu, Xunxiang [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gibson, Brian T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-06-01

    The advanced welding facility within a hot cell at the Radiochemical Engineering Development Center of Oak Ridge National Laboratory (ORNL), which has been jointly funded by the U.S. Department of Energy (DOE), Office of Nuclear Energy, Light Water Reactor Sustainability Program and the Electric Power Research Institute, Long Term Operations Program and the Welding and Repair Technology Center, is in the final phase of development. Research and development activities in this facility will involve direct testing of advanced welding technologies on irradiated materials in order to address the primary technical challenge of helium induced cracking that can arise when conventional fusion welding techniques are utilized on neutron irradiated stainless steels and nickel-base alloys. This report details the effort that has been required since the beginning of fiscal year 2017 to initiate welding research and development activities on irradiated materials within the hot cell cubicle, which houses welding sub-systems that include laser beam welding (LBW) and friction stir welding (FSW) and provides material containment within the hot cell.

  2. AFIP-3 Irradiation Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Danielle M Perez; M. A. Lillo; G. S. Chang; G. A. Roth; N. E. Woolstenhulme; D. M. Wachs

    2012-03-01

    The Advanced Test Reactor (ATR) Full size plate In center flux trap Position (AFIP) experiment AFIP-3 was designed to evaluate the performance of monolithic fuels at a prototypic scale of 2.25 inches x 21.5 inches x 0.050 inches (5.75 cm x 54.6 cm x 0.13cm). The AFIP-3 experiment was fabricated by hot isostatic pressing (HIP) and consists of two plates, one with a zirconium (Zr) diffusion barrier and one with a silicon (Si) enhanced fuel/clad interface1,2. The following report summarizes the life of the AFIP-3 experiment through end of irradiation, including a brief description of the safety analysis, as-run neutronic analysis results, hydraulic testing results, and thermal analysis results.

  3. AFIP-3 Irradiation Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Danielle M Perez; M. A. Lillo; G. S. Chang; G. A. Roth; N. E. Woolstenhulme; D. M. Wachs

    2011-05-01

    The Advanced Test Reactor (ATR) Full size plate In center flux trap Position (AFIP) experiment AFIP-3 was designed to evaluate the performance of monolithic fuels at a prototypic scale of 2.25 inches x 21.5 inches x 0.050 inches (5.75 cm x 54.6 cm x 0.13cm). The AFIP-3 experiment was fabricated by hot isostatic pressing (HIP) and consists of two plates, one with a zirconium (Zr) diffusion barrier and one with a silicon (Si) enhanced fuel/clad interface1,2. The following report summarizes the life of the AFIP-3 experiment through end of irradiation, including a brief description of the safety analysis, as-run neutronic analysis results, hydraulic testing results, and thermal analysis results.

  4. AFIP-1 Irradiation Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    D. M. Perez; M. A. Lillo; G. S. Chang; G. A. Roth; N. E. Woolstenhulme; D. M. Wachs

    2011-05-01

    The Advanced Test Reactor (ATR) Full size plate In center flux trap Position (AFIP) experiment AFIP-1 was designed to demonstrate the performance of second-generation dispersion fuels at a prototypic scale with a length of 21.5 inches (54.6 cm), width of 2.25 inches (5.75 cm) and a thickness of 0.050 inch (0.13 cm). The experiment was fabricated using commercially standard practices at BWX Technology, Inc. (BWXT). The U-7Mo fuel particles were supplied by the Korean Atomic Energy Research Institute (KAERI) using equipment intended for commercial supply. Two fuel plates were tested that incorporated two different matrix compositions, Al-2Si and Al-4043.1 The following report summarizes the life of the AFIP-1 experiment through end of irradiation, including a brief description of the safety analysis, as-run neutronic analysis results, hydraulic testing results, and thermal analysis results

  5. AFIP-2 Irradiation Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Danielle M Perez; M. A. Lillo; G. S. Chang; G. A. Roth; N. E. Woolstenhulme; D. M. Wachs

    2011-05-01

    The Advanced Test Reactor (ATR) Full size plate In center flux trap Position (AFIP) experiment AFIP-2 was designed to evaluate the performance of monolithic fuels at a prototypic scale of 2.25 inches x 21.5 inches x 0.050 inches (5.75 cm x 54.6 cm x 0.13cm). The AFIP-2 experiment was fabricated by friction bond (FB) and consists of two plates, one with a zirconium (Zr) diffusion barrier and one with a silicon (Si) enhanced fuel/clad interface1,2. The following report summarizes the life of the AFIP-2 experiment through end of irradiation, including a brief description of the safety analysis, as-run neutronic analysis results, hydraulic testing results, and thermal analysis results. The safety analyses performed for AFIP-2 are summarized in Table 5 of the following report.

  6. AFIP-2 Irradiation Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Danielle M Perez

    2011-04-01

    The Advanced Test Reactor (ATR) Full size plate In center flux trap Position (AFIP) experiment AFIP-2 was designed to evaluate the performance of monolithic fuels at a prototypic scale of 2.25 inches x 21.5 inches x 0.050 inches (5.75 cm x 54.6 cm x 0.13cm). The AFIP-2 experiment was fabricated by friction bond (FB) and consists of two plates, one with a zirconium (Zr) diffusion barrier and one with a silicon (Si) enhanced fuel/clad interface1,2. The following report summarizes the life of the AFIP-2 experiment through end of irradiation, including a brief description of the safety analysis, as-run neutronic analysis results, hydraulic testing results, and thermal analysis results. The safety analyses performed for AFIP-2 are summarized in Table 5 of the following report.

  7. High dose irradiation with hyperfractionation

    Energy Technology Data Exchange (ETDEWEB)

    Asakura, Hideo; Kurashima, Shoji; Hasegawa, Maki; Akiyama, Kazuo (Sagamihara National Hospital, Kanagawa (Japan))

    1990-10-01

    From March 1988 to January 1990, 12 patients including 7 primary lung cancers, 2 lung metastases of colorectal cancer, and each 1 gall bladder cancer, ovarian cancer, and spinal cord metastasis of prostatic cancer, received {sup 60}Co-irradiation with high dose by hyperfractionation. This hyperfractionation consisted of 1.2 Gy per fraction, twice a day with 6 hour interval, and 5 days (10 fractions) a week. The total dose administered was 81.6{approx}100 Gy. The acute reaction of skin, lung, and intestines was tolerable, and it seemed that the late damage of normal tissues was slighter and the treatment result was favorable in comparison with the conventional fractionation, but this estimation was not definite because of short observation period. It was discussed that further reduction of dose per fraction (1 Gy or below) and more increased total dose (100 Gy or more) would be promising in hyperfractionation. (author).

  8. Evaluation of CERES surface irradiance products

    Science.gov (United States)

    Kato, S.; Loeb, N. G.; Rose, F. G.; Rutan, D. A.; Doelling, D.; Radkevich, A.; Ham, S. H.

    2014-12-01

    Understanding the surface radiation budget is important for several reasons. At the global and large temporal scales, it should balance with the sum of surface latent and sensible heat fluxes and ocean heating. At regional scales, it is an indispensable boundary condition for ocean or snow models or any other models that need energy input to the surface. NASA's Clouds and the Earth's Radiant Energy System (CERES) project provides surface irradiance data products for a range of temporal and spatial scales computed using a radiative transfer model initialized using satellite-derived cloud and aerosol properties. Other inputs to the radiative transfer model include temperature and humidity profiles from NASA Global Modeling and Assimilation Office's (GMAO) reanalysis. The CERES team uses more than 80 surface observation sites located over land and ocean to evaluate computed irradiances. When computed monthly 1° by 1° gridded mean downward irradiances are compared with 10 years of observed irradiances, the bias averaged over all land and ocean sites are, respectively, -1.7 Wm-2 and 4.7 Wm-2 for shortwave and -1.0 Wm-2 and -2.0 Wm-2 for longwave. The shortwave agreement is significantly better than other satellite-based surface irradiance products. One of reasons for the better agreement is careful treatment of diurnal cycle of clouds by merging 3-hourly geostationary satellite-derived cloud properties. In addition, computed surface irradiance variability shows a remarkable agreement with observed variability. However, these data sets have their shortcomings. The uncertainty in nighttime surface longwave irradiance over polar regions is larger than that of other regions primarily due to the difficulty of cloud detection and large uncertainties in skin temperature and near-surface temperature and humidity. The large uncertainty in polar region surface irradiances hampers, for example, investigation of surface radiation budget changes in response to changes in sea ice

  9. Craniospinal irradiation techniques

    Energy Technology Data Exchange (ETDEWEB)

    Scarlatescu, Ioana, E-mail: scarlatescuioana@gmail.com; Avram, Calin N. [Faculty of Physics, West University of Timisoara, Bd. V. Parvan 4, 300223 Timisoara (Romania); Virag, Vasile [County Hospital “Gavril Curteanu” - Oradea (Romania)

    2015-12-07

    In this paper we present one treatment plan for irradiation cases which involve a complex technique with multiple beams, using the 3D conformational technique. As the main purpose of radiotherapy is to administrate a precise dose into the tumor volume and protect as much as possible all the healthy tissues around it, for a case diagnosed with a primitive neuro ectoderm tumor, we have developed a new treatment plan, by controlling one of the two adjacent fields used at spinal field, in a way that avoids the fields superposition. Therefore, the risk of overdose is reduced by eliminating the field divergence.

  10. Weight loss and dropout during a commercial weight-loss program including a very-low-calorie diet, a low-calorie diet, or restricted normal food: observational cohort study 1 2 3

    OpenAIRE

    Hemmingsson, Erik; Johansson, Kari; Eriksson, Jonas; Sundström, Johan; Neovius, Martin; Marcus, Claude

    2012-01-01

    Background: The effectiveness of commercial weight-loss programs consisting of very-low-calorie diets (VLCDs) and low-calorie diets (LCDs) is unclear. Objective: The aim of the study was to quantify weight loss and dropout during a commercial weight-loss program in Sweden (Itrim; cost: $1300/€1000; all participants paid their own fee). Design: This observational cohort study linked commercial weight-loss data with National Health Care Registers. Weight loss was induced with a 500-kcal liquid-...

  11. Facilities for studying radiation damage in nonmetals during irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Levy, P.W.

    1984-08-01

    Two facilities have been developed for making optical absorption, luminescence and other measurements on a single sample before, during and after irradiation. One facility uses /sup 60/Co gamma rays and the other 0.5 to 3 MeV electrons from an accelerator. Optical relays function as spectrophotometers, luminescenc detectors, etc. All radiation sensitive components are outside of walk-in irradiation chambers; all measurement control and data recording is computerized. Irradiations are made at controlled temperatures between 5K and 900/sup 0/C. The materials studied include glasses, quartz, alkali halides (especially natural rock salt), organic crystals, etc. As determined from color center measurements the damage formation rate in all materials studied at 25/sup 0/C or above is strongly temperature dependent. The defect concentration during irradiation is usually much greater than that measured after irradiation. The fraction of defects annealing after irradiation and the annealing rate usually increases as the irradiation temperature increases. The completed studies demonstrate that, in most cases, the extent of maximum damage and the damage formation and annealing kinetics can be determined only by making measurements during irradiation.

  12. The role of prophylactic cranial irradiation in regionally advanced non-small cell lung cancer. A Southwest Oncology Group Study

    Energy Technology Data Exchange (ETDEWEB)

    Rusch, V.W.; Griffin, B.R.; Livingston, R.B. (Univ. of Washington, Seattle (USA))

    1989-10-01

    Lung cancer is the most common malignant disease in the United States. Only the few tumors detected very early are curable, but there has been some progress in the management of more advanced non-small cell lung cancer, particularly in regionally inoperable disease. Prevention of central nervous system relapse is an important issue in this group of patients because brain metastases ultimately develop in 20% to 25% of them. Seventy-three patients with regionally advanced non-small cell lung cancer were entered into a Phase II trial of neutron chest radiotherapy sandwiched between four cycles of chemotherapy including cisplatin, vinblastine, and mitomycin C. Prophylactic cranial irradiation was administered concurrently with chest radiotherapy (3000 cGy in 10 fractions in 15 patients; 3600 cGy in 18 fractions in the remaining 50 patients). Patients underwent computed tomographic scan of the brain before treatment and every 3 months after treatment. The initial overall response rate was 79%, but 65 of the 73 patients have subsequently died of recurrent disease. Median follow-up is 9 months for all 73 patients and 26 months for eight long-term survivors. No patient who completed the prophylactic cranial irradiation program had clinical or radiologic brain metastases. Toxic reactions to prophylactic cranial irradiation included reversible alopecia in all patients, progressive dementia in one patient, and possible optic neuritis in one patient. Both of these patients received 300 cGy per fraction of irradiation. The use of prophylactic cranial irradiation has been controversial, but its safety and efficacy in this trial supports its application in a group of patients at high risk for central nervous system relapse. Further evaluation of prophylactic cranial irradiation in clinical trials for regionally advanced non-small cell lung cancer is warranted.

  13. International Developments of Food Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Loaharanu, P. [Head, Food Preservation Section, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Wagramerstr. 5, A-1400, Vienna (Austria)

    1997-12-31

    Food irradiation is increasingly accepted and applied in many countries in the past decade. Through its use, food losses and food-borne diseases can be reduced significantly, and wider trade in many food items can be facilitated. The past five decades have witnessed a positive evolution on food irradiation according to the following: 1940`s: discovery of principles of food irradiation; 1950`s: initiation of research in advanced countries; 1960`s: research and development were intensified in some advanced and developing countries; 1970`s: proof of wholesomeness of irradiated foods; 1980`s: establishment of national regulations; 1990`s: commercialization and international trade. (Author)

  14. Food irradiation and the consumer

    Science.gov (United States)

    A Thomas, P.

    The poster presents a review of research work undertaken on the perception and understanding that consumers have of food irradiation. Food irradiation is not a revolutionary new food processing technique, in fact it is probably one of the most investigated methods presently available. Many countries such as Belgium, France, Denmark, Italy, Spain, the Netherlands and the United States of America permit food irradiation. In Britain it is presently banned although this is currently under review. Awareness of food irradiation by the general public in Britain, although not extensively researched would appear to be increasing, especially in the light of recent media coverage. New quantitative and qualitative work indicates that the general public are concerned about the safety and effectiveness of food irradiation. Research has shown that a large proportion of consumers in Britain, if given the opportunity to purchase irradiated food, would not do so. Further exploration into this response revealed the fact that consumers are confused over what food irradiation is. In addition, there is concern over the detection of irradiated food. The views presented in this paper, of the consumer reaction to irradiated food are of great importance to those involved in the food industry and industries allied to it, which are ultimately dependent on the consumer for their commercial survival.

  15. Food irradiation and sterilization

    Science.gov (United States)

    Josephson, Edward S.

    Radiation sterilization of food (radappertization) requires exposing food in sealed containers to ionizing radiation at absorbed doses high enough (25-70 kGy) to kill all organisms of food spoilage and public health significance. Radappertization is analogous to thermal canning is achieving shelf stability (long term storage without refrigeration). Except for dry products in which autolysis is negligible, the radappertization process also requires that the food be heated to an internal temperature of 70-80°C (bacon to 53°C) to inactivate autolytic enzymes which catalyze spoilage during storage without refrigeration. To minimize the occurence of irradiation induced off-flavors and odors, undesirable color changes, and textural and nutritional losses from exposure to the high doses required for radappertization, the foods are vacuum sealed and irradiated frozen (-40°C to -20°C). Radappertozed foods have the characteristic of fresh foods prepared for eating. Radappertization can substitute in whole or in part for some chemical food additives such as ethylene oxide and nitrites which are either toxic, carcinogenic, mutagenic, or teratogenic. After 27 years of testing for "wholesomeness" (safety for consumption) of radappertized foods, no confirmed evidence has been obtained of any adverse effecys of radappertization on the "wholesomeness" characteristics of these foods.

  16. Status of Neutron Irradiation of Non-Nuclear Materials at HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Kee-Nam; Cho, Man-Soon; Shin, Yoon-Taek; Park, Seng-Jae; Kang, Young Hwan; Jun, Byung-Hyuk; Kim, Chan-Joong; Park, Sang-Jun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    The irradiation facilities have been mostly utilized for the KAERI nuclear research projects relevant to a commercial nuclear power reactor such as the ageing management and safety evaluation of the components. Based on the accumulated experience, HANARO has recently supported national R and D projects relevant to new nuclear systems including the System-integrated Modular Advanced Reactor (SMART), research reactors, and future nuclear systems. As neutron irradiation affects the structure of a material, radiation induced modification of materials has become a perspective method for the purposeful changes in material properties. Some irradiation tests of electro-magnetic materials were also performed at HANARO for scientific research of universities and the demand for neutron irradiation of the materials is increasing rapidly. Another research reactor that will specialize in radio-isotope and neutron transmutation doping (NTD) Si production and the demonstration of reactor design is under construction in Korea. Therefore, HANARO will specialize more on irradiation research. Based on its accumulated irradiation experience, HANARO has recently started new support of R and D relevant to the irradiation of electro-magnetic materials. In this paper, the status of utilization of the HANARO irradiation facilities for non-nuclear materials and the possibility of researches on new electro-magnetic materials using neutron irradiation are surveyed to encourage the utilization of HANARO. HANARO irradiation facilities have been actively utilized for various material irradiation tests requested by users. Although most irradiation tests have been related to national R and D relevant to nuclear power, demand for neutron irradiation of electro-magnetic materials is rapidly increasing at HANARO. Another research reactor, the KIJANG research reactor (KJRR), is under construction in Korea. New irradiation facilities including Neutron Transmutation Doping (NTD) facilities for power

  17. Behavior of beryllium pebbles under irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Dalle-Donne, M.; Scaffidi-Argentina, F. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Inst. fuer Neutronenphysik und Reactortechnik; Baldwin, D.L.; Gelles, D.S.; Greenwood, L.R.; Kawamura, H.; Oliver, B.M.

    1998-01-01

    Beryllium pebbles are being considered in fusion reactor blanket designs as neutron multiplier. An example is the European `Helium Cooled Pebble Bed Blanket.` Several forms of beryllium pebbles are commercially available but little is known about these forms in response to fast neutron irradiation. Commercially available beryllium pebbles have been irradiated to approximately 1.3 x 10{sup 22} n/cm{sup 2} (E>1 MeV) at 390degC. Pebbles 1-mm in diameter manufactured by Brush Wellman, USA and by Nippon Gaishi Company, Japan, and 3-mm pebbles manufactured by Brush Wellman were included. All were irradiated in the below-core area of the Experimental Breeder Reactor-II in Idaho Falls, USA, in molybdenum alloy capsules containing helium. Post-irradiation results are presented on density change measurements, tritium release by assay, stepped-temperature anneal, and thermal ramp desorption tests, and helium release by assay and stepped-temperature anneal measurements, for Be pebbles from two manufacturing methods, and with two specimen diameters. The experimental results on density change and tritium and helium release are compared with the predictions of the code ANFIBE. (author)

  18. Independent Review of AFC 2A, 2B, and 2E ATR Irradiation Tests

    Energy Technology Data Exchange (ETDEWEB)

    M. Cappiello; R. Hobbins; K. Penny; L. Walters

    2014-01-01

    As part of the Department of Energy Advanced Fuel Cycle program, a series of fuels development irradiation tests have been performed in the Advanced Test Reactor (ATR) at the Idaho National Laboratory. These tests are providing excellent data for advanced fuels development. The program is focused on the transmutation of higher actinides which best can be accomplished in a sodium-cooled fast reactor. Because a fast test reactor is no longer available in the US, a special test vehicle is used to achieve near-prototypic fast reactor conditions (neutron spectra and temperature) for use in ATR (a water-cooled thermal reactor). As part of the testing program, there were many successful tests of advanced fuels including metals and ceramics. Recently however, there have been three experimental campaigns using metal fuels that experienced failure during irradiation. At the request of the program, an independent review committee was convened to review the post-test analyses performed by the fuels development team, to assess the conclusions of the team for the cause of the failures, to assess the adequacy and completeness of the analyses, to identify issues that were missed, and to make recommendations for improvements in the design and operation of future tests. Although there is some difference of opinion, the review committee largely agreed with the conclusions of the fuel development team regarding the cause of the failures. For the most part, the analyses that support the conclusions are sufficient.

  19. Irradiation of structural materials in contact with lead bismuth eutectic in the high flux reactor

    Energy Technology Data Exchange (ETDEWEB)

    Magielsen, A.J., E-mail: magielsen@nrg.eu [Nuclear Research and Consultancy Group, Westerduinweg 3, Postbus 25, 1755 ZG Petten (Netherlands); Jong, M.; Bakker, T.; Luzginova, N.V.; Mutnuru, R.K.; Ketema, D.J.; Fedorov, A.V. [Nuclear Research and Consultancy Group, Westerduinweg 3, Postbus 25, 1755 ZG Petten (Netherlands)

    2011-08-31

    In the framework of the materials domain DEMETRA in the European Transmutation research and development project EUROTRANS, irradiation experiment IBIS has been performed in the High Flux Reactor in Petten. The objective was to investigate the synergystic effects of irradiation and lead bismuth eutectic exposure on the mechanical properties of structural materials and welds. In this experiment ferritic martensitic 9 Cr steel, austenitic 316L stainless steel and their welds have been irradiated for 250 Full Power Days up to a dose level of 2 dpa. Irradiation temperatures have been kept constant at 300 deg. C and 500 deg. C. During the post-irradiation test phase, tensile tests performed on the specimens irradiated at 300 deg. C have shown that the irradiation hardening of ferritic martensitic 9 Cr steel at 1.3 dpa is 254 MPa, which is in line with the irradiation hardening obtained for ferritic martensitic Eurofer97 steel investigated in the fusion program. This result indicates that no LBE interaction at this irradiation temperature is present. A visual inspection is performed on the specimens irradiated in contact with LBE at 500 deg. C and have shown blackening on the surface of the specimens and remains of LBE that makes a special cleaning procedure necessary before post-irradiation mechanical testing.

  20. TFE Verification Program

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The objective of the semiannual progress report is to summarize the technical results obtained during the latest reporting period. The information presented herein will include evaluated test data, design evaluations, the results of analyses and the significance of results. The program objective is to demonstrate the technology readiness of a TFE (thermionic fuel element) suitable for use as the basic element in a thermionic reactor with electric power output in the 0.5 to 5.0 MW(e) range, and a full-power life of 7 years. The TFE Verification Program builds directly on the technology and data base developed in the 1960s and early 1970s in an AEC/NASA program, and in the SP-100 program conducted in 1983, 1984 and 1985. In the SP-100 program, the attractive features of thermionic power conversion technology were recognized but concern was expressed over the lack of fast reactor irradiation data. The TFE Verification Program addresses this concern.

  1. A technique for pediatric total skin electron irradiation.

    Science.gov (United States)

    Bao, Qinan; Hrycushko, Brian A; Dugas, Joseph P; Hager, Frederick H; Solberg, Timothy D

    2012-03-20

    Total skin electron irradiation (TSEI) is a special radiotherapy technique which has generally been used for treating adult patients with mycosis fungoides. Recently, two infants presented with leukemia cutis isolated to the skin requiring TSEI. This work discusses the commissioning and quality assurance (QA) methods for implementing a modified Stanford technique using a rotating harness system to position sedated pediatric patients treated with electrons to the total skin. Commissioning of pediatric TSEI consisted of absolute calibration, measurement of dosimetric parameters, and subsequent verification in a pediatric patient sized cylindrical phantom using radiographic film and optically stimulated luminance (OSL) dosimeters. The depth of dose penetration under TSEI treatment condition was evaluated using radiographic film sandwiched in the phantom and demonstrated a 2 cm penetration depth with the maximum dose located at the phantom surface. Dosimetry measurements on the cylindrical phantom and in-vivo measurements from the patients suggested that, the factor relating the skin and calibration point doses (i.e., the B-factor) was larger for the pediatric TSEI treatments as compared to adult TSEI treatments. Custom made equipment, including a rotating plate and harness, was fabricated and added to a standard total body irradiation stand and tested to facilitate patient setup under sedated condition. A pediatric TSEI QA program, consisting of daily output, energy, flatness, and symmetry measurements as well as in-vivo dosimetry verification for the first cycle was developed. With a long interval between pediatric TSEI cases, absolute dosimetry was also repeated as part of the QA program. In-vivo dosimetry for the first two infants showed that a dose of ± 10% of the prescription dose can be achieved over the entire patient body. Though pediatric leukemia cutis and the subsequent need for TSEI are rare, the ability to commission the technique on a modified TBI stand

  2. A technique for pediatric total skin electron irradiation

    Directory of Open Access Journals (Sweden)

    Bao Qinan

    2012-03-01

    Full Text Available Abstract Background Total skin electron irradiation (TSEI is a special radiotherapy technique which has generally been used for treating adult patients with mycosis fungoides. Recently, two infants presented with leukemia cutis isolated to the skin requiring TSEI. This work discusses the commissioning and quality assurance (QA methods for implementing a modified Stanford technique using a rotating harness system to position sedated pediatric patients treated with electrons to the total skin. Methods and Results Commissioning of pediatric TSEI consisted of absolute calibration, measurement of dosimetric parameters, and subsequent verification in a pediatric patient sized cylindrical phantom using radiographic film and optically stimulated luminance (OSL dosimeters. The depth of dose penetration under TSEI treatment condition was evaluated using radiographic film sandwiched in the phantom and demonstrated a 2 cm penetration depth with the maximum dose located at the phantom surface. Dosimetry measurements on the cylindrical phantom and in-vivo measurements from the patients suggested that, the factor relating the skin and calibration point doses (i.e., the B-factor was larger for the pediatric TSEI treatments as compared to adult TSEI treatments. Custom made equipment, including a rotating plate and harness, was fabricated and added to a standard total body irradiation stand and tested to facilitate patient setup under sedated condition. A pediatric TSEI QA program, consisting of daily output, energy, flatness, and symmetry measurements as well as in-vivo dosimetry verification for the first cycle was developed. With a long interval between pediatric TSEI cases, absolute dosimetry was also repeated as part of the QA program. In-vivo dosimetry for the first two infants showed that a dose of ± 10% of the prescription dose can be achieved over the entire patient body. Conclusion Though pediatric leukemia cutis and the subsequent need for TSEI are

  3. Results of the Irradiation of R6R018 in the Advanced Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Adam B Robinson; Daniel Wachs; Pavel Medvedev; Curtis Clark; Gray Chang; Misti Lillo; Jan-Fong Jue; Glenn Moore; Jared Wight

    2010-04-01

    For over 30 years the Reduced Enrichment for Research and Test Reactors (RERTR) program has worked to provide the fuel technology and analytical support required to convert research and test reactors from nuclear fuels that utilize highly enriched uranium (HEU) to fuels based on low-enriched uranium (LEU) (defined as <20% U-235). This effort is driven by a desire to minimize international civilian commerce in weapons usable materials. The RERTR fuel development program has executed a wide array of fuel tests over the last decade that clearly established the viability of research reactor fuels based on uranium-molybdenum (U-Mo) alloys. Fuel testing has included a large number of dispersion type fuels capable of providing uranium densities up to approximately 8.5 g U/cc (~1.7 g U-235/cc at 20% enrichment). The dispersion fuel designs tested are very similar to existing research test reactor fuels in that the U-Mo particles simply replace the current fuel phase within the matrix. In 2003 it became evident that the first generation U-Mo-based dispersion fuel within an aluminum matrix exhibited significant fuel performance problems at high power and burn-up. These issues have been successfully addressed with a modest modification to the matrix material composition. Testing has shown that small additions of silicon (2–5 wt%) to the aluminum (Al) matrix stabilizes the fuel performance. The fuel plate R6R018 which was irradiated in the Advanced Test Reactor (ATR) as part of the RERTR-9B experiment was part of an investigation into the role of the silicon content in the matrix. This plate consisted of a U-7Mo fuel phase dispersed in an Al-3.5Si matrix clad in Al-6061. This report outlines the fabrication history, the as fabricated analysis performed prior to irradiation, the irradiation conditions, the post irradiation examination results, and an analysis of the plates behavior.

  4. Sensorial evaluation of irradiated mangoes

    Energy Technology Data Exchange (ETDEWEB)

    Broisler, Paula Olhe; Cruz, Juliana Nunes da; Sabato, Susy Frey [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mails: paulabroisler@hotmail.com; juliananc@ig.com.br; sfsabato@ipen.br

    2007-07-01

    Mango (Mangifera indica L.) is a tropical fruit of great economical relevance in the world, mainly for tropical countries like Brazil. It consists in the second tropical fruit more important grown in the world. On the other hand it is a very perishable fruit and its delivery to distant points is restricted due to short shelf life at environmental temperature. Food irradiation process is applied to fruits for their preservation, once it promotes disinfestation and even maturation retard, among other mechanisms. The Brazilian legislation permits the food irradiation and does not restrict the doses to be delivered. In order to verify eventual changes, sensorial evaluation is very important to study how irradiation affects the quality of the fruit and its acceptability. Mangoes were irradiated in a Cobalto-60 source, from the Radiation Technology Center, CTR, of IPEN/CNEN-SP at doses 0,5 kGy e 0,75 kGy. The sensorial evaluation was measured through Acceptance Test where irradiated samples were offered together with control sample to the tasters who answered their perception through hedonic scale. The parameters Color, Odor, Flavor and Texture were analyzed. Statistical analysis showed that only Odor parameter was different from control (sample irradiated at 0.5 kGy). Few tasters indicated that irradiated mangoes had fewer odors in relation to non-irradiated samples. (author)

  5. Concurrent in situ ion irradiation transmission electron microscope

    Energy Technology Data Exchange (ETDEWEB)

    Hattar, K., E-mail: khattar@sandia.gov; Bufford, D.C.; Buller, D.L.

    2014-11-01

    An in situ ion irradiation transmission electron microscope has been developed and is operational at Sandia National Laboratories. This facility permits high spatial resolution, real time observation of electron transparent samples under ion irradiation, implantation, mechanical loading, corrosive environments, and combinations thereof. This includes the simultaneous implantation of low-energy gas ions (0.8–30 keV) during high-energy heavy ion irradiation (0.8–48 MeV). Initial results in polycrystalline gold foils are provided to demonstrate the range of capabilities.

  6. Consumer acceptance of irradiated food

    Energy Technology Data Exchange (ETDEWEB)

    Loaharanu, P. [Head, Food Preservation Section, Joint FAO/ IAEA Division of Nuclear Techniques in Food and Agriculture, Wagramerstr. 5, A-1400, Vienna (Austria)

    1997-12-31

    There was a widely held opinion during the 1970`s and 1980`s that consumers would be reluctant to purchase irradiated food, as it was perceived that consumers would confuse irradiated food with food contaminated by radionuclides. Indeed, a number of consumer attitude surveys conducted in several western countries during these two decades demonstrated that the concerns of consumers on irradiated food varied from very concerned to seriously concerned.This paper attempts to review parameters conducting in measuring consumer acceptance of irradiated food during the past three decades and to project the trends on this subject. It is believed that important lessons learned from past studies will guide further efforts to market irradiated food with wide consumer acceptance in the future. (Author)

  7. Irradiation of fresh fish

    Science.gov (United States)

    Yueh-jen, Yen; Jin-lai, Zhou; Shao-chun, Lai

    Occasionally, in China, marine products can not be provided for the markets in good quality, for during the time when they are being transported from the sea port to inland towns or even at the time when they are unloaded from the ship, they are beginning to spoil. Obviously, it is very important that appropiate measures should be taken to prevent them from decay. Our study has proved that the shelf life of fresh Flatfish (Cynoglossue robustus) and Silvery pomfret (stromateoides argenteus), which, packed in sealed containers, are irradiated by 1.5 kGy, 2.2 kGy and 3.0 kGy, can be stored for about 13-26 days at 3° - 5° C.

  8. Irradiation for xenogeneic transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Halperin, E.C.; Knechtle, S.J.; Harland, R.C.; Yamaguchi, Yasua; Sontag, M.; Bollinger, R.R. (Duke Univ., Durham, NC (USA). Dept. of Radiology Duke Univ., Durham, NC (USA). Dept. of Microbiology and Immunology)

    1990-05-01

    Xenogeneic transplantation (XT) is the transplantation of organs or tissues from a member of one species to a member of another. Mammalian species frequently have circulating antibody which is directed against the foreign organ irrespective of known prior antigen exposure. This antibody may lead to hyperacute rejection once it ensues so efforts must be directed towards eliminating the pre-existing antibody. In those species in which hyperacute rejection of xenografts does not occur, cell-mediated refection, similar to allograft rejection, may occur. It is in the prevention of this latter form of refection that radiation is most likely to be beneficial in XT. Both total lymphoid irradiation (TLI) and selective lyphoid irradiation (LSI) have been investigated for use in conjunction with XT. TLI has contributed to the prolongation of pancreatic islet-cell xenografts from hamsters to rats. TLI has also markedly prolonged the survival of cardiac transplants from hamsters to rats. A more modest prolongation of graft survival has been seen with the use of TLI in rabbit-to-rat exchanges. Therapy with TLI, cyclosporine, and splenectomy has markedly prolonged the survival of liver transplants from hamsters to rats, and preliminary data suggest that TLI may contribute to the prolongation of graft survival in the transplantation of hearts from monkeys to baboons. SLI appears to have prolonged graft survival, when used in conjunction with anti-lymphocyte globulin, in hamster-to-rat cardiac graft exchanges. The current state of knowledge of the use of irradiaiton in experimental XT is reviewed. (author). 38 refs.; 1 fig.; 5 tabs.

  9. Irradiation of mangoes as a quarantine treatment

    Energy Technology Data Exchange (ETDEWEB)

    Bustos R, M.E.; Enkerlin H, W.; Toledo A, J.; Reyes F, J.; Casimiro G, A

    1991-06-15

    This research project was conducted following guidelines of research protocols for post-harvest treatments developed by the United States Department of Agriculture CUSA. Laboratory bioassays included the irradiation of mangoes infested with third instar larvae of Anastrepha serpentina (Wied), A. ludens (Loew), A. obliqua (Macquart) and Ceratitis capitata (Wied) , at doses from 10 to 250 Gy. Irradiation doses were applied using a Co-60 AECL Model JS-7400 irradiator. The design was chosen to obtain a maximum to minimum ratio equal to, or less than, 1.025. C. capitata was the species most tolerant to irradiation. A dose of 60 Gy applied to third instar fruit fly larvae sterilized this species and prevented emergence of adults of the other three species. A dose of 250 Gy was required to prevent emergence of C. capitata. In fertility tests using emerged adults of A . Iudens, and A. obliqua a dose of 30 Gy gave 45 % and 27 % fertility, respectively. Adults of A. serpentina that emerged, died before reaching sexual maturity. The confirmatory tests, at probit-9 security level, were done at 100 Gy for the three species of Anastrepha and at 150 Gy for C. capitata. The quality of mangoes irradiated up to 1000 Gy was evaluated by chemical, physiological, and sensorial tests. The determination of vitamin C indicated that there was no loss of the nutritive value of the fruit. It also was observed that fruit metabolism was not accelerated since no significant increase in respiration or transpiration was registered and consumers accepted both treated and untreated fruit in the same way. (Author)

  10. Browsing, Understanding, and Accessing Solar Irradiance Data via LISIRD

    Science.gov (United States)

    Wilson, A.; Lindholm, D. M.; Pankratz, C. K.

    2012-12-01

    The Laboratory for Atmospheric and Space Physics, LASP, has been conducting research in Atmospheric and Space science for over 60 years. In particular, LASP has made a variety of space-based measurements of solar irradiance, which provide crucial input for research and modeling in solar-terrestrial interactions, space physics, planetary, atmospheric, and climate sciences. These data sets are generally time series of measurements, solar indices, and spectra. Unlike many Earth science data sets, they are not geolocated and so cannot be referenced via latitude and longitude coordinates. Thus they are not appropriate for or interoperable with many existing geo scientific data access and analysis tools and need somewhat specialized tools to aid users in their understanding and use. The LASP Solar Irradiance Data Center, LISIRD, http://lasp.colorado.edu/lisird, is designed to allow the science community and the public to explore and access solar irradiance and related data sets. LISIRD's interactive plotting allows users to investigate and download spectral data sets from a variety of missions. We have recently expanded our offerings and now serve TIMED SEE Level 2, Level 3, and Level 4 data sets. We continue to serve SORCE Solar Spectral Irradiance, Total Solar Irradiance, and Magnesium II and well as the Flare Irradiance Spectral Model (FISM) and other data sets. LISIRD leverages middleware, the LASP Time series Server (LaTiS), that provides access to time series data based on time, wavelength, and parameter. LaTiS can read a wide variety of input formats from both local and remote sources, so many data sets can be served in their native format. It also supports dynamic data reformatting, so users can request the data and times in formats of their choice. LaTiS supports data subsetting so that users may download only regions of interest, and can stream the data directly into a computer program via a RESTful API in an automated fashion. We continue to improve LISIRD not

  11. Evolution of glycaemia during irradiation syndrome; Evolution de la glycemie au cours du syndrome d'irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Raisonnier, A. [Commissariat a l' Energie Atomique, Fontenay aux Roses (France). Centre d' Etudes Nucleaires

    1967-03-15

    The evolution of glycaemia following irradiation has been followed in the rat and pig. The results concerning a case of human accidental exposure have also been included. The author has tried to see whether the observed variations are reproducible and have a prognostic value. (author) [French] L'evolution de la glycemie a ete suivie, chez le rat et le porc, apres irradiation. Les resultats relatifs a une irradiation accidentelle humaine sont egalement rapportes. L'auteur cherche a definir si les variations observees sont reproductibles et ont une valeur pronostique. (auteur)

  12. Research report: User's manual for computer program AT81y003 SHABERTH. Steady state and transient thermal analysis of a shaft bearing system including ball, cylindrical and tapered roller bearings

    Science.gov (United States)

    Hadden, G. B.; Kleckner, R. J.; Ragen, M. A.; Sheynin, L.

    1981-01-01

    The SHABERTH program is capable of simulating the thermomechanical performance of a load support system consisting of a flexible shaft supported by up to five rolling element bearings. Any combination of ball, cylindrical, and tapered roller bearings can be used to support the shaft. The user can select models in calculating lubricant film thickness and traction forces. The formulation of the cage pocket/rolling element interaction model was revised to improve solution numerical convergence characteristics.

  13. Electron paramagnetic resonance identification of irradiated cuttlefish (Sepia officinalis L.)

    Energy Technology Data Exchange (ETDEWEB)

    Duliu, O.G. E-mail: odlu@scut.fizica.unibuc.ro

    2000-05-15

    Gamma-ray irradiated fresh cuttlefish bone display very intense Electron Paramagnetic Resonance (EPR) spectra, which could be attributed to five different centers, including CO{sup -}{sub 2}, previously observed in irradiated carbonates. All centers display a positive correlation with the absorbed dose, described by linear or saturation type dependencies. During 36 h of isothermal annealing at 100 deg. C, three of them decayed with time exponentially, one remained constant, while the EPR spectrum amplitude of the fifth increased.

  14. Electron paramagnetic resonance identification of irradiated cuttlefish (Sepia officinalis L.).

    Science.gov (United States)

    Duliu, O G

    2000-05-01

    Gamma-ray irradiated fresh cuttlefish bone display very intense Electron Paramagnetic Resonance (EPR) spectra, which could be attributed to five different centers, including CO2-, previously observed in irradiated carbonates. All centers display a positive correlation with the absorbed dose, described by linear or saturation type dependencies. During 36 h of isothermal annealing at 100 degrees C, three of them decayed with time exponentially, one remained constant, while the EPR spectrum amplitude of the fifth increased.

  15. Scoring irradiation mucositis in head and neck cancer patients

    Energy Technology Data Exchange (ETDEWEB)

    Spijkervet, F.K.L.; Panders, A.K. (Departments of Oral and Maxillofacial Surgery, University Hospital Groningen (Netherlands)); Saene, H.K.F. van (Medical Microbiology, University of Liverpool (UK)); Vermey, A. (Department of Surgery Oncology Division, University Hospital Groningen (Netherlands)); Mehta, D.M. (Department of Radiotherapy, University Hospital Groningen (Netherlands))

    1989-01-01

    Irradiation mucositis is defined as an inflammatory-like process of the oropharyngeal mucosa following therapeutic irradiation of patients who have head and neck cancer. Clinically, it is a serious side effect because severe mucositis can cause generalized problems (weight loss, nasogastic tube feedings) and interferes with the well-being of the patient seriously. Grading mucositis is important for the evaluation of preventive and therapeutic measures. The object of this study was to develop a scoring method based on local mucositis signs only. Four clinical local signs of mucositis were used in this score: white discoloration, erythema, pseudomembranes and ulceration. Mucositis of the oral cavity was calcualted during conventional irradiation protocol for 8 distinguishable areas using the 4 signs and their extent. A prospective evaluation of this method in 15 irradiated head and neck cancer patients displayed an S-curve reflecting a symptomless first irradiation week, followed by a rapid and steady increase of white discoloration, erythema and pseudomembranes during the second and third week. Oral candidiasis, generalized symptoms such as weight loss and the highest mucositis scores were seen after 3 weeks irradiation. The novel mucositis scoring method may be of value in studying the effect of hygiene programs, topical application of disinfectans or antibiotics on oral mucositis. (author).

  16. Irradiation selects for p53-deficient hematopoietic progenitors.

    Directory of Open Access Journals (Sweden)

    Andriy Marusyk

    2010-03-01

    Full Text Available Identification and characterization of mutations that drive cancer evolution constitute a major focus of cancer research. Consequently, dominant paradigms attribute the tumorigenic effects of carcinogens in general and ionizing radiation in particular to their direct mutagenic action on genetic loci encoding oncogenes and tumor suppressor genes. However, the effects of irradiation are not limited to genetic loci that encode oncogenes and tumor suppressors, as irradiation induces a multitude of other changes both in the cells and their microenvironment which could potentially affect the selective effects of some oncogenic mutations. P53 is a key tumor suppressor, the loss of which can provide resistance to multiple genotoxic stimuli, including irradiation. Given that p53 null animals develop T-cell lymphomas with high penetrance and that irradiation dramatically accelerates lymphoma development in p53 heterozygous mice, we hypothesized that increased selection for p53-deficient cells contributes to the causal link between irradiation and induction of lymphoid malignancies. We sought to determine whether ionizing irradiation selects for p53-deficient hematopoietic progenitors in vivo using mouse models. We found that p53 disruption does not provide a clear selective advantage within an unstressed hematopoietic system or in previously irradiated BM allowed to recover from irradiation. In contrast, upon irradiation p53 disruption confers a dramatic selective advantage, leading to long-term expansion of p53-deficient clones and to increased lymphoma development. Selection for cells with disrupted p53 appears to be attributable to several factors: protection from acute irradiation-induced ablation of progenitor cells, prevention of irradiation-induced loss of clonogenic capacity for stem and progenitor cells, improved long-term maintenance of progenitor cell fitness, and the disabling/elimination of competing p53 wild-type progenitors. These studies

  17. Irradiation temperature dependence of production efficiency of lattice defects in some neutron-irradiated oxides

    Energy Technology Data Exchange (ETDEWEB)

    Okada, Moritami [Research Reactor Institute, Kyoto University, Kumatori-cho, Sennan-gun, Osaka 5900494 (Japan)]. E-mail: okada@rri.kyoto-u.ac.jp; Atobe, Kozo [Faculty of Science, Naruto University of Education, Naruto, Tokushima 7728502 (Japan); Nakagawa, Masuo [Faculty of Education, Kagawa University, Takamatsu, Kagawa 7608522 (Japan)

    2004-11-01

    Temperature dependence of production efficiency of irradiation-induced defects in neutron-irradiated oxides has been investigated. Some oxide single crystals, MgO, {alpha}-Al{sub 2}O{sub 3} (sapphire) and TiO{sub 2} (rutile), were irradiated at several controlled temperatures, 10, 20, 50, 100, 150 and 200 K, using the low-temperature irradiation facility of Kyoto University Reactor (KUR-LTL), and at ambient temperature ({approx}370 K) in the same facility. Irradiation temperature dependence of production efficiency of a 1 {mu}m band in TiO{sub 2} differs greatly from that of anion vacancy (F-type centers) in MgO and {alpha}-Al{sub 2}O{sub 3}. Results for MgO and {alpha}-Al{sub 2}O{sub 3} show steep negative gradients from 10 to 370 K, whereas that for TiO{sub 2} includes a valley between 40 and 60 K and a hump at about 130 K, and then disappear at about 200 K. In MgO and {alpha}-Al{sub 2}O{sub 3}, this behavior can be explained by the recombination of Frenkel pairs, which is activated at higher temperature. In TiO{sub 2}, in addition to the recombination mechanism, a covalent bonding property is thought to be exerted strong influence, and it is suggested that a disappearance of the 1 {mu}m band at above 200 K is due to the recombination process of Frenkel pairs which is caused by the irradiation-induced crystallization.

  18. Post irradiation characterization of beryllium and beryllides after high temperature irradiation up to 3000 appm helium production in HIDOBE-01

    Energy Technology Data Exchange (ETDEWEB)

    Fedorov, A.V., E-mail: fedorov@nrg.eu [Nuclear Research and Consultancy Group, Westerduinweg 3, Postbus 25, Petten, 1755 ZG (Netherlands); Til, S. van; Stijkel, M.P. [Nuclear Research and Consultancy Group, Westerduinweg 3, Postbus 25, Petten, 1755 ZG (Netherlands); Nakamichi, M. [Japan Atomic Energy Agency, Rokkasho (Japan); Zmitko, M. [The European Joint Undertaking for ITER and the Development of Fusion Energy, c/ Josep Pla, n° 2, Torres Diagonal Litoral, Edificio B3, Barcelona 08019 (Spain)

    2016-01-15

    Titanium beryllides are considered as advanced candidate material for neutron multiplier for the helium cooled pebble bed (HCPB) and/or the water cooled ceramic breeder (WCCB) breeder blankets. In the HIDOBE-01 (HIgh DOse irradiation of BEryllium) experiment, beryllium and beryllide pellets with 5 at% and 7 at% Ti are irradiated at four different target temperatures (T{sub irr}): 425 °C, 525 °C, 650 °C and 750 °C up to the dose corresponding to 3000 appm He production in beryllium. The pellets were supplied by JAEA. During post irradiation examinations the critical properties of volumetric swelling and tritium retention were studied. Both titanium beryllide grades show significantly less swelling than the beryllium grade, with the difference increasing with the irradiation temperature. The irradiation induced swelling was studied by using direct dimensions. Both beryllide grades showed much less swelling as compare to the reference beryllium grade. Densities of the grades were studied by Archimedean immersion and by He-pycnometry, giving indications of porosity formation. While both beryllide grades show no significant reduction in density at all irradiation temperatures, the beryllium density falls steeply at higher T{sub irr}. Finally, the tritium release and retention were studied by temperature programmed desorption (TPD). Beryllium shows the same strong tritium retention as earlier observed in studies on beryllium pebbles, while the tritium inventory of the beryllides is significantly less, already at the lowest T{sub irr} of 425 °C.

  19. Method for analyzing passive silicon carbide thermometry with a continuous dilatometer to determine irradiation temperature

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, Anne A., E-mail: campbellaa@ornl.gov [Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Porter, Wallace D.; Katoh, Yutai [Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Snead, Lance L. [Massachusetts Institute of Technology, Cambridge, MA 02139 (United States)

    2016-03-01

    Highlights: • Annealing of SiC via continuous dilatometry to determine irradiation temperature. • Wrote a program to analyze dilatometry results to determine irradiation temperature. • Dilatometry results are consistent with results from a historical technique. • Computer program was written in an open-source language and is available for others. - Abstract: Silicon carbide is used as a passive post-irradiation temperature monitor because the irradiation defects will anneal out above the irradiation temperature. The irradiation temperature is determined by measuring a property change after isochronal annealing, i.e., lattice spacing, dimensions, electrical resistivity, thermal diffusivity, or bulk density. However, such methods are time-consuming since the steps involved must be performed in a serial manner. This work presents the use of thermal expansion from continuous dilatometry to calculate the SiC irradiation temperature, which is an automated process requiring minimal setup time. Analysis software was written that performs the calculations to obtain the irradiation temperature and removes possible user-introduced error while standardizing the analysis. This method has been compared to an electrical resistivity and isochronal annealing investigation, and the results revealed agreement of the calculated temperatures. These results show that dilatometry is a reliable and less time-intensive process for determining irradiation temperature from passive SiC thermometry.

  20. Craniospinal Irradiation for Trilateral Retinoblastoma Following Ocular Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Marks, Lawrence B.; Bentel, Gunilla; Sherouse, George W.; Spencer, David P.; Light, Kim

    2015-01-15

    A case study is presented. Craniospinal radiotherapy and a three-field pineal boost for trilateral retinoblastoma were delivered to a patient previously irradiated for ocular retinoblastoma. The availability of CT-based three-dimensional treatment planning provided the capability of identifying the previously irradiated volume as a three-dimensional anatomic structure and of designing a highly customized set of treatment beams that minimized reirradiation of that volume.

  1. Respiratory Cytology--Current Trends Including Endobronchial Ultrasound-Guided Biopsy and Electromagnetic Navigational Bronchoscopy: Analysis of Data From a 2013 Supplemental Survey of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology.

    Science.gov (United States)

    Sturgis, Charles D; Marshall, Carrie B; Barkan, Guliz A; Booth, Christine N; Kurtycz, Daniel F I; Souers, Rhona J; Keylock, Joren B; Tabatabai, Z Laura; Russell, Donna K; Moriarty, Ann T; Doyle, Mary A; Thomas, Nicole; Yildiz-Aktas, Isil Z; Collins, Brian T; Laucirica, Rodolfo; Crothers, Barbara A

    2016-01-01

    Nongynecologic cytology (NGC) practices are expanding in relationship to historical gynecologic cytology screening programs. Bronchopulmonary cytology is experiencing an evolution regarding new procedural types. The College of American Pathologists (CAP) tracks practice patterns in NGC by developing questionnaires, surveying participants, and analyzing respondent data. To analyze responses to a 2013 CAP supplemental survey from the Interlaboratoy Comparison Program on bronchopulmonary NGC. The "NGC 2013 Supplemental Questionnaire: Demographics in Performance and Reporting of Respiratory Cytology" was mailed to 2074 laboratories. The survey response rate was 42% (880 of 2074) with 90% of respondents (788 of 880) indicating that their laboratories evaluated cytology bronchopulmonary specimens. More than 95% of respondents indicated interpreting bronchial washings (765 of 787) and bronchial brushings (757 of 787). A minority of laboratories (43%, 340 of 787) dealt with endobronchial ultrasound-guided samples, and an even smaller fraction of laboratories (14%, 110 of 787) saw cases from electromagnetic navigational bronchoscopy. Intraprocedural adequacy assessments by pathologists (and less often by cytotechnologists or pathologists-in-training) were routinely performed in percutaneous transthoracic aspiration cases (74%, 413 of 560) with less involvement for other case types. Most laboratories reported that newly diagnosed primary pulmonary adenocarcinomas were triaged for molecular testing of epidermal growth factor receptor and anaplastic lymphoma kinase. The parameters examined in this 2013 survey provide a snapshot of current pulmonary cytopathology practice and may be used as benchmarks in the future.

  2. Food irradiation: current problems and future potential

    Energy Technology Data Exchange (ETDEWEB)

    Kilcast, D. [Food Research Association, Leatherhead (United Kingdom)

    1995-12-31

    Food irradiation is one of a set of processing technologies that can be used to increase the microbiological safety and shelf-life of a wide range of foods. Ionizing radiation is used to generate highly active chemical species within the food, which react with DNA. Under normal usage conditions, the food receives a pasteurizing treatment that gives a valuable reduction in common food-spoilage organisms and food pathogens. This review describes how the process is used in practice, including the benefits and limitations. The nature of changes to food components are outlined, together with the development of practical detection methods that utilize these changes. The legislative position of food irradiation is outlined, with the specific example of the introduction of the technology within the UK. The reasons for the slow uptake in the use of the technology are discussed, and the problem of consumer acceptance is addressed. (author).

  3. Evaluation of gamma irradiation of teas

    Energy Technology Data Exchange (ETDEWEB)

    Gerolis, Luanai G.L.; Lameiras, Fernando S.; Menezes, Maria A.B.C.; Leal, Alexandre S., E-mail: luanaigraz@yahoo.com.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Krambrock, Klaus, E-mail: klaus@fisica.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Fisica. Lab. de Ressonancia Paramagnetica Eletronica

    2013-07-01

    There is a growing interest in the determination of non-essential traces elements in agroindustrial products. The continuous ingestion and accumulation in the organism of such elements, that may be toxic, can cause hazards to the human health in the long term. Reliable analytical techniques are necessary to monitor such products, including teas. In this work, the neutron activation technique is being employed to determine the trace elements in teas, due to its high sensibility and the possibility to perform a multi-elementary analysis. The gamma irradiation of teas is also being studied, because the shelf life can be extended and no chemical product is added to the teas. There is a concern related to the formation of free radicals in the teas, which is being accessed with electronic paramagnetic resonance. The results of the gamma irradiation up to 20 kGy of Camelia sinensis, Ilex paraguariensis, and Matricaria recutita are presented. (author)

  4. Neutron irradiation induced amorphization of silicon carbide

    Energy Technology Data Exchange (ETDEWEB)

    Snead, L.L.; Hay, J.C. [Oak Ridge National Lab., TN (United States)

    1998-09-01

    This paper provides the first known observation of silicon carbide fully amorphized under neutron irradiation. Both high purity single crystal hcp and high purity, highly faulted (cubic) chemically vapor deposited (CVD) SiC were irradiated at approximately 60 C to a total fast neutron fluence of 2.6 {times} 10{sup 25} n/m{sup 2}. Amorphization was seen in both materials, as evidenced by TEM, electron diffraction, and x-ray diffraction techniques. Physical properties for the amorphized single crystal material are reported including large changes in density ({minus}10.8%), elastic modulus as measured using a nanoindentation technique ({minus}45%), hardness as measured by nanoindentation ({minus}45%), and standard Vickers hardness ({minus}24%). Similar property changes are observed for the critical temperature for amorphization at this neutron dose and flux, above which amorphization is not possible, is estimated to be greater than 130 C.

  5. Three year trend analysis of food irradiation education for elementary school students

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yoon Seok; Lee, Seung Koo; Park, Pil Han; Han, Eun Ok [Dept. of Education and Research, Korea Academy of Nuclear Safety, Seoul (Korea, Republic of)

    2015-10-15

    In this context, the present study was designed as part of a large-scale communication strategy for the enhancement of public understanding through the creation of a national consensus about irradiated foodstuffs. In order to provide basic data required to formulate such a strategy, elementary school students were selected as the research population in this study, in consideration of the high ripple effects expected in this population group. Analyzed were differences in perception, knowledge, and attitude regarding irradiated foods as a result of the implementation of an education program designed to enhance the understanding of food irradiation, between the baseline (pre-education) level and the post-education level. Bruhn et al. (1986) reported that even consumers with little knowledge or negative views of irradiation show favorable attitudes towards irradiated foodstuffs after being exposed to promotional materials or campaigns on processing techniques using food irradiation and their advantages.

  6. Proton irradiation effects on beryllium – A macroscopic assessment

    Energy Technology Data Exchange (ETDEWEB)

    Simos, Nikolaos, E-mail: simos@bnl.gov [Nuclear Sciences & Technology Department, Brookhaven National Laboratory, Upton, NY, 11973 (United States); Elbakhshwan, Mohamed [Nuclear Sciences & Technology Department, Brookhaven National Laboratory, Upton, NY, 11973 (United States); Zhong, Zhong [Photon Sciences, NSLS II, Brookhaven National Laboratory, Upton, NY, 11973 (United States); Camino, Fernando [Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, NY, 11973 (United States)

    2016-10-15

    Beryllium, due to its excellent neutron multiplication and moderation properties, in conjunction with its good thermal properties, is under consideration for use as plasma facing material in fusion reactors and as a very effective neutron reflector in fission reactors. While it is characterized by unique combination of structural, chemical, atomic number, and neutron absorption cross section it suffers, however, from irradiation generated transmutation gases such as helium and tritium which exhibit low solubility leading to supersaturation of the Be matrix and tend to precipitate into bubbles that coalesce and induce swelling and embrittlement thus degrading the metal and limiting its lifetime. Utilization of beryllium as a pion production low-Z target in high power proton accelerators has been sought both for its low Z and good thermal properties in an effort to mitigate thermos-mechanical shock that is expected to be induced under the multi-MW power demand. To assess irradiation-induced changes in the thermal and mechanical properties of Beryllium, a study focusing on proton irradiation damage effects has been undertaken using 200 MeV protons from the Brookhaven National Laboratory Linac and followed by a multi-faceted post-irradiation analysis that included the thermal and volumetric stability of irradiated beryllium, the stress-strain behavior and its ductility loss as a function of proton fluence and the effects of proton irradiation on the microstructure using synchrotron X-ray diffraction. The mimicking of high temperature irradiation of Beryllium via high temperature annealing schemes has been conducted as part of the post-irradiation study. This paper focuses on the thermal stability and mechanical property changes of the proton irradiated beryllium and presents results of the macroscopic property changes of Beryllium deduced from thermal and mechanical tests.

  7. CONTRIBUTION OF HANARO IRRADIATION TECHNOLOGIES TO NATIONAL NUCLEAR R&D

    Directory of Open Access Journals (Sweden)

    KEE NAM CHOO

    2014-08-01

    Full Text Available HANARO is a multipurpose research reactor located at the Korea Atomic Energy Research Institute (KAERI. Since the commencement of its operation in 1995, various neutron irradiation facilities, such as rabbit irradiation facilities, fuel test loop (FTL facilities, capsule irradiation facilities, and neutron transmutation doping (NTD facilities, have been developed and actively utilized for various nuclear material irradiation tests requested by users from research institutes, universities, and industries. Most irradiation tests have been related to national R&D relevant to present nuclear power reactors such as the ageing management and safety evaluation of the components. Based on the accumulated experience as well as the sophisticated requirements of users, HANARO has recently supported national R&D projects relevant to new nuclear systems including the System-integrated Modular Advanced Reactor (SMART, research reactors, and future nuclear systems. This paper documents the current state and utilization of irradiation facilities in HANARO, and summarizes ongoing research efforts to deploy advanced irradiation technology.

  8. Review of the quality and safety of irradiated food. Master's thesis

    Energy Technology Data Exchange (ETDEWEB)

    Cox, J.H.

    1987-01-01

    This monograph will describe the food-irradiation process and summarizing its historical development as a way to prolong the shelf-life of food and prevent the spread of food-borne illness. It will also examine of the known effects of irradiation on food quality. Including a presentation of the effect of irradiation on the flavor, appearance, and smell of food. The nutritional adequacy of irradiated foods and several improvements in some foods caused by irradiation are also discussed. Finally, a discussion of the safety issues associated with the process and its products. The safety of irradiated foods is an issue of growing concern to the American public. While irradiation shows great potential for reducing foodborne illness, the formation of radiolytic products, the physical dangers of radiation, and the possibility of cancer or genetic mutation worries many people.

  9. Contribution of HANARO irradiation technologies to national nuclear R and D

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Kee Nam; Cho, Man Soon; Yang, Sung Woo; Park, Sang Jun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-08-15

    HANARO is a multipurpose research reactor located at the Korea Atomic Energy Research Institute (KAERI). Since the commencement of its operation in 1995, various neutron irradiation facilities, such as rabbit irradiation facilities, fuel test loop (FTL) facilities, capsule irradiation facilities, and neutron transmutation doping (NTD) facilities, have been developed and actively utilized for various nuclear material irradiation tests requested by users from research institutes, universities, and industries. Most irradiation tests have been related to national R and D relevant to present nuclear power reactors such as the ageing management and safety evaluation of the components. Based on the accumulated experience as well as the sophisticated requirements of users, HANARO has recently supported national R and D projects relevant to new nuclear systems including the System-integrated Modular Advanced Reactor (SMART), research reactors, and future nuclear systems. This paper documents the current state and utilization of irradiation facilities in HANARO, and summarizes ongoing research efforts to deploy advanced irradiation technology.

  10. Stillbirths and male irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Boice, John D. Jr. [International Epidemiology Institute, Rockville, MD (United States)]. E-mail: boicej@compuserve.com; Robison, Leslie L. [University of Minnesota, Minneapolis, MN (United States); Mertens, Ann [University of Texas M D Anderson Cancer Center, Houston, TX (United States); Stovall, Marilyn; Green, Daniel M.; Mulvihill, John J.; ); Roswell Park Cancer Institute, Buffalo, NY (United States); University of Oklahoma, Oklahoma City, OK (US))

    2000-09-01

    Little (1999) recently reviewed the evidence that paternal preconception irradiation in the Sellafield workforce (Parker et al 1999) and among Japanese atomic bomb survivors (Otake et al 1990) might be associated with an increased risk of stillbirth. He concluded that the association reported for radiation workers was statistically incompatible with the absence of an association seen among the exposed Japanese parents. These studies and analyses illustrate the considerable difficulty in assessing stillbirths conceived by men exposed to ionising radiation at work. For example, occupational doses may not be sufficiently large to result in a detectable effect and maternal factors that are associated with stillbirths and important to adjust for may not be available. These papers also bring to focus a relevant but not well-studied public health issue, namely, what are the reproductive risks for men and women exposed to potential mutagens? We wish to emphasise here the theoretical and practical advantages of addressing this issue in persons not with low dose occupational or acute atomic bomb exposures, but with higher dose medical experiences; in particular, in survivors of cancers of childhood, adolescents, and young adulthood (Blatt 1999, Bryne et al 1998, Sankila et al 1998, Green et al 1997, Hawkins and Stevens 1996). Letter-to-the-editor.

  11. LWRS ATR Irradiation Testing Readiness Status

    Energy Technology Data Exchange (ETDEWEB)

    Kristine Barrett

    2012-09-01

    The Light Water Reactor Sustainability (LWRS) Program was established by the U.S. Department of Energy Office of Nuclear Energy (DOE-NE) to develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the life of the current reactors. The LWRS Program is divided into four R&D Pathways: (1) Materials Aging and Degradation; (2) Advanced Light Water Reactor Nuclear Fuels; (3) Advanced Instrumentation, Information and Control Systems; and (4) Risk-Informed Safety Margin Characterization. This report describes an irradiation testing readiness analysis in preparation of LWRS experiments for irradiation testing at the Idaho National Laboratory (INL) Advanced Test Reactor (ATR) under Pathway (2). The focus of the Advanced LWR Nuclear Fuels Pathway is to improve the scientific knowledge basis for understanding and predicting fundamental performance of advanced nuclear fuel and cladding in nuclear power plants during both nominal and off-nominal conditions. This information will be applied in the design and development of high-performance, high burn-up fuels with improved safety, cladding integrity, and improved nuclear fuel cycle economics

  12. Irradiation pretreatment for coal desulfurization

    Science.gov (United States)

    Hsu, G. C.

    1979-01-01

    Process using highly-penetrating nuclear radiation (Beta and Gamma radiation) from nuclear power plant radioactive waste to irradiate coal prior to conventional desulfurization procedures increases total extraction of sulfur.

  13. UV irradiance radiometers calibration procedure

    OpenAIRE

    Doctorovich I. V.; Butenko V. K.; Hodovaniouk V. N.; Fodchuk I. M.; Yuriev V. G.

    2008-01-01

    The paper deals with the problems arising at calibration of narrow-band spectral-sensitive radiometers. The procedure of irradiance unit transfer to UV radiometers — UV radiometers calibration procedure — is presented.

  14. URAM-2 Cryogenic Irradiation Facility

    CERN Document Server

    Shabalin, E P; Kulikov, S A; Kulagin, E N; Melihov, V V; Belyakov, A A; Golovanov, L B; Borzunov, Yu T; Konstantinov, V I; Androsov, A V

    2002-01-01

    The URAM-2 irradiation facility has been built and mounted at the channel No. 3 of the IBR-2 reactor. It was constructed for study of radiolysis effects by fast neutron irradiation in some suitable for effective cold neutron production materials (namely: solid methane, methane hydrate, water ice, etc.). The facility cooling system is based on using liquid helium as a coolant material. The original charging block of the rig allows the samples to be loaded by condensing gas into irradiation cavity or by charging beads of ice prepared before. Preliminary tests for each facility block and assembling them at the working position were carried out. Use of the facility for study accumulation of chemical energy under irradiation at low temperature in materials mentioned above and its spontaneous release was started.

  15. The 1997 North American Interagency Intercomparison of Ultraviolet Spectroradiometers Including Narrowband Filter Radiometers.

    Science.gov (United States)

    Lantz, Kathleen; Disterhoft, Patrick; Early, Edward; Thompson, Ambler; DeLuisi, John; Berndt, Jerry; Harrison, Lee; Kiedron, Peter; Ehramjian, James; Bernhard, Germar; Cabasug, Lauriana; Robertson, James; Mou, Wanfeng; Taylor, Thomas; Slusser, James; Bigelow, David; Durham, Bill; Janson, George; Hayes, Douglass; Beaubien, Mark; Beaubien, Arthur

    2002-01-01

    The fourth North American Intercomparison of Ultraviolet Monitoring Spectroradiometers was held September 15 to 25, 1997 at Table Mountain outside of Boulder, Colorado, USA. Concern over stratospheric ozone depletion has prompted several government agencies in North America to establish networks of spectroradiometers for monitoring solar ultraviolet irradiance at the surface of the Earth. The main purpose of the Intercomparison was to assess the ability of spectroradiometers to accurately measure solar ultraviolet irradiance, and to compare the results between instruments of different monitoring networks. This Intercomparison was coordinated by NIST and NOAA, and included participants from the ASRC, EPA, NIST, NSF, SERC, USDA, and YES. The UV measuring instruments included scanning spectroradiometers, spectrographs, narrow band multi-filter radiometers, and broadband radiometers. Instruments were characterized for wavelength accuracy, bandwidth, stray-light rejection, and spectral irradiance responsivity. The spectral irradiance responsivity was determined two to three times outdoors to assess temporal stability. Synchronized spectral scans of the solar irradiance were performed over several days. Using the spectral irradiance responsivities determined with the NIST traceable standard lamp, and a simple convolution technique with a Gaussian slit-scattering function to account for the different bandwidths of the instruments, the measured solar irradiance from the spectroradiometers excluding the filter radiometers at 16.5 h UTC had a relative standard deviation of ±4 % for wavelengths greater than 305 nm. The relative standard deviation for the solar irradiance at 16.5 h UTC including the filter radiometer was ±4 % for filter functions above 300 nm.

  16. Advanced Numerical Model for Irradiated Concrete

    Energy Technology Data Exchange (ETDEWEB)

    Giorla, Alain B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-03-01

    In this report, we establish a numerical model for concrete exposed to irradiation to address these three critical points. The model accounts for creep in the cement paste and its coupling with damage, temperature and relative humidity. The shift in failure mode with the loading rate is also properly represented. The numerical model for creep has been validated and calibrated against different experiments in the literature [Wittmann, 1970, Le Roy, 1995]. Results from a simplified model are shown to showcase the ability of numerical homogenization to simulate irradiation effects in concrete. In future works, the complete model will be applied to the analysis of the irradiation experiments of Elleuch et al. [1972] and Kelly et al. [1969]. This requires a careful examination of the experimental environmental conditions as in both cases certain critical information are missing, including the relative humidity history. A sensitivity analysis will be conducted to provide lower and upper bounds of the concrete expansion under irradiation, and check if the scatter in the simulated results matches the one found in experiments. The numerical and experimental results will be compared in terms of expansion and loss of mechanical stiffness and strength. Both effects should be captured accordingly by the model to validate it. Once the model has been validated on these two experiments, it can be applied to simulate concrete from nuclear power plants. To do so, the materials used in these concrete must be as well characterized as possible. The main parameters required are the mechanical properties of each constituent in the concrete (aggregates, cement paste), namely the elastic modulus, the creep properties, the tensile and compressive strength, the thermal expansion coefficient, and the drying shrinkage. These can be either measured experimentally, estimated from the initial composition in the case of cement paste, or back-calculated from mechanical tests on concrete. If some

  17. Effect of irradiation on the dental pulp tissues in streptozotocin-induced diabetic rats

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Ho Duk; Hwang, Eui Hwan; Lee, Sang Rae [Kyunghee University College of Medicine, Seoul (Korea, Republic of)

    2005-03-15

    To observe the histological changes in the pulp tissues of mandibular molars in streptozotocin-induced diabetic rats after irradiation. The male Sprague-Dawley rats weighing approximately 250 gm were divided into four groups : control, diabetes, irradiation, and diabetes-irradiation groups. Diabetes mellitus was induced in the rats by injecting streptozotocin. Rats in control and irradiation groups were injected with citrate buffer only. After 5 days, the head and neck region of the rats in irradiation and diabetes-irradiation groups were irradiated with a single absorbed dose of 10 Gy. All the rats were sacrificed at 3, 7, 14, 21, and 28 days after irradiation. The specimen including the mandibular molars were sectioned and observed using a histopathological method. In the diabetes group, capillary dilatation was observed. However, there was no obvious morphologic alteration of the odontoblasts. In the irradiation group, generalized necrosis of the dental pulp tissues was observed. Vacuolation of the odontoblasts and dilatation of the capillaries were noted in the early experimental phases. In the diabetes-irradiation group, generalized degeneration of the dental pulp tissues was observed. Vacuolation of the dental pulp cells and the odontoblasts was noted in the late experimental phases. This experiment suggest that dilatation of the capillaries in the dental pulp tissue is induced by diabetic state, and generalized degeneration of the dental pulp tissues is induced by irradiation of the diabetic group.

  18. Data on post irradiation experiments of heat resistant ceramic composite materials. PIE for 97M-13A

    Energy Technology Data Exchange (ETDEWEB)

    Baba, Shin-ichi; Ishihara, Masahiro; Souzawa, Shizuo [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment; Sekino, Hajime [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2003-03-01

    The research on the radiation damage mechanism of heat resistant ceramic composite materials is one of the research subjects of the innovative basic research in the field of high temperature engineering, using the High Temperature engineering Test Reactor (HTTR). Three series of irradiation tests on the heat resistant ceramic composite materials, first to third irradiation test program, were carried out using the Japan Material Testing Reactor (JMTR). This is a summary report on the first irradiation test program; irradiation induced dimensional change, thermal expansion coefficient, X-ray diffraction and {gamma}-ray spectrum are reported. (author)

  19. Recovery of uranium from an irradiated solid target after removal of molybdenum-99 produced from the irradiated target

    Energy Technology Data Exchange (ETDEWEB)

    Reilly, Sean Douglas; May, Iain; Copping, Roy; Dale, Gregory Edward

    2017-10-17

    A process for minimizing waste and maximizing utilization of uranium involves recovering uranium from an irradiated solid target after separating the medical isotope product, molybdenum-99, produced from the irradiated target. The process includes irradiating a solid target comprising uranium to produce fission products comprising molybdenum-99, and thereafter dissolving the target and conditioning the solution to prepare an aqueous nitric acid solution containing irradiated uranium. The acidic solution is then contacted with a solid sorbent whereby molybdenum-99 remains adsorbed to the sorbent for subsequent recovery. The uranium passes through the sorbent. The concentrations of acid and uranium are then adjusted to concentrations suitable for crystallization of uranyl nitrate hydrates. After inducing the crystallization, the uranyl nitrate hydrates are separated from a supernatant. The process results in the purification of uranyl nitrate hydrates from fission products and other contaminants. The uranium is therefore available for reuse, storage, or disposal.

  20. Smelting of Scandium by Microwave Irradiation.

    Science.gov (United States)

    Fujii, Satoshi; Tsubaki, Shuntaro; Inazu, Naomi; Suzuki, Eiichi; Wada, Yuji

    2017-09-27

    Scandium is being explored as an alloying element for aluminum alloys, which are gaining importance as high-performance lightweight structural alloys in the transportation industry. A few years ago, Sc was also found to be suitable for use in electrical devices. High-Sc-content ScAlN thin films have attracted significant attention because of their strong piezoelectricity. The piezoelectric response of ScAlN suggests that ScAlN thin films formed on a hard substrate would be suitable surface acoustic wave wideband filters for next-generation wireless communication systems. However, it is often difficult to use ScAlN thin films in MEMS devices-including acoustic ones-because of the extremely high price of metallic Sc, given the difficulty associated with smelting it. Here, we propose a novel process for smelting Sc metal by microwave irradiation. Sc metal was able to be obtained successfully from ScF₃ through a microwave-irradiation-based carbon reduction reaction. The reaction temperature for this reduction process was approximately 880°C, which is half of that for the conventional smelting process involving reduction with Ca. Thus, the proposed microwave irradiation process has significant potential for use in the smelting of Sc metal.

  1. Perspectives on treatment with irradiation in Slovenia

    Directory of Open Access Journals (Sweden)

    Primož Strojan

    2007-12-01

    Full Text Available Background: Radiotherapy is one of the three main modalities of cancer treatment. However, effective treatment with radiotherapy may only be assured by highly advanced irradiation facilities, including systems for planning, performing and quality control of irradiation. The second requirement assuring an effective treatment is proper capacities of treatment units and computer equipment to provide a timely access to treatment to > 50 % of all cancer patients and a proper structure and number of staff specialized in handling with radiotherapy equipment. In Slovenia, only 38 % of cancer patients are treated with radiotherapy. In general, the waiting times of patients referred to radiotherapy are too long. Therefore, further development and upgrading of irradiation facilities will remain a priority in oncology in Slovenia also in the future. At the same time, in our endeavors to meet the set goals, we have been facing unforeseen problems both with human resources and inadequate financial appreciation of radiotherapeutic services that, without significant national aid, do not yield sufficient funds for renewal and upgrading of equipment and its further expansion.

  2. Smelting of Scandium by Microwave Irradiation

    Directory of Open Access Journals (Sweden)

    Satoshi Fujii

    2017-09-01

    Full Text Available Scandium is being explored as an alloying element for aluminum alloys, which are gaining importance as high-performance lightweight structural alloys in the transportation industry. A few years ago, Sc was also found to be suitable for use in electrical devices. High-Sc-content ScAlN thin films have attracted significant attention because of their strong piezoelectricity. The piezoelectric response of ScAlN suggests that ScAlN thin films formed on a hard substrate would be suitable surface acoustic wave wideband filters for next-generation wireless communication systems. However, it is often difficult to use ScAlN thin films in MEMS devices—including acoustic ones—because of the extremely high price of metallic Sc, given the difficulty associated with smelting it. Here, we propose a novel process for smelting Sc metal by microwave irradiation. Sc metal was able to be obtained successfully from ScF3 through a microwave-irradiation-based carbon reduction reaction. The reaction temperature for this reduction process was approximately 880°C, which is half of that for the conventional smelting process involving reduction with Ca. Thus, the proposed microwave irradiation process has significant potential for use in the smelting of Sc metal.

  3. ESR investigations of gamma irradiated medical devices.

    Science.gov (United States)

    Turker, N Selcan; Özer, A Yekta; Çolak, Şeyda; Kutlu, Burak; Nohutçu, Rahime

    2017-12-01

    Guided tissue regeneration (GTR) and guided bone regeneration (GBR) biomaterials have been employed in recent years for periodontal procedures. In the present study, widely used dental GTR/GBR biomaterials (grafts: G1, G2, G3 and membranes: M1, M2, M3, M4) were exposed to gamma irradiation at an absorbed dose range of 0-50kGy and the radiolytic intermediates that have been created in the samples upon irradiation were characterized in detail by Electron Spin Resonance (ESR) spectroscopy. We aimed to standardize the measurement conditions for practical applications of gamma radiation sterilization of GTR/GBR biomaterials. We investigated the characteristic features of free radicals in gamma irradiated GTR/GBR biomaterials and examined the stability of the induced radicals at room temperature and accelerated stability conditions with ESR spectroscopy including dose-response curves, microwave power studies, dosimetric features of the biomaterials, variations of the peak heights with temperature, and long term stabilities of the radical species. Long-term stability studies have shown that G1 is quite stable even in accelerated storage conditions. The signal intensities of graft-type GTR/GBR biomaterials stored in normal and stability conditions have decreased very rapidly even only a few days after gamma irradiation sterilization. Thus, those samples indicating relatively low stability features can be very good candidates for the radiosterilization process. The beta-tricalcium phosphate and PLGA containing G1 and M1 respectively have found to be the most gamma stable bone substitute biomaterials and be safely sterilized by gamma radiation. ESR spectroscopy is an appropriate technique in giving important detailed spectroscopic findings in the gamma radiation sterilization studies of GTR/GBR biomaterials. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Late effects of thoracic irradiation in children

    Energy Technology Data Exchange (ETDEWEB)

    Boelling, T.; Koenemann, S.; Ernst, I.; Willich, N. [Dept. of Radiotherapy, Univ. Hospital of Muenster (Germany)

    2008-06-15

    Purpose: to summarize the literature regarding the late effects of radiotherapy to the thorax in childhood and adolescence with special emphasis on cardiac and pulmonary impairment. Material und methods: the literature was critically reviewed using the PubMed {sup registered} database with the key words 'late effects', 'late sequelae', 'child', 'childhood', 'adolescence', 'radiation', 'radiotherapy', 'thorax', 'lung', 'heart', and 'pulmonary'. Results: 17 publications dealing with radiation-induced pulmonary and cardiac late sequelae in children could be identified and were analyzed in detail. 29 further publications with additional information were also included in the analysis. Pulmonary function impairment after mediastinal irradiation arose in one third of all pediatric patients, even when treatment was performed with normofractionated lower doses (15-25 Gy). Whole lung irradiation was regularly followed by pulmonary function impairment with differing rates in several reports. However, clinically symptomatic function impairment like dyspnea was less frequent. Irradiation of up to 25 Gy (single doses {<=} 2 Gy) to the heart showed little or no cardiac toxicity in analyses of irradiated children (median follow-up 1.3-14.3 years). Doses of > 25 Gy (single doses {<=} 2-3.3 Gy) led to several cardiac dysfunctions. However, new data from adults with longer follow-up may indicate threshold doses as low as 1 Gy. Impairment of skeletal growth, breast hypoplasia, and secondary malignancy were further potential late sequelae. Conclusion: several retrospective reports described radiation-associated late sequelae in children. However, there is still a lack of sufficient data regarding the characterization of dose-volume effects. (orig.)

  5. Microstructure and microhardness of CLAM steel irradiated up to 20.8 dpa in STIP-V

    Energy Technology Data Exchange (ETDEWEB)

    Peng, Lei, E-mail: penglei@ustc.edu.cn [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, 230027 (China); Ge, Hongen [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, 230027 (China); Laboratory for Nuclear Materials, Paul Scherrer Institut, 5232, Villigen PSI (Switzerland); Dai, Yong [Laboratory for Nuclear Materials, Paul Scherrer Institut, 5232, Villigen PSI (Switzerland); Huang, Qunying [Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); Ye, Minyou [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, 230027 (China)

    2016-01-15

    Specimens of China low activation martensitic (CLAM) steel were irradiated in the fifth experiment of SINQ target irradiation program (STIP-V) up to 20.8 dpa/1564 appm He. Microhardness measurements and transmission electron microscope (TEM) observations have been performed to investigate irradiation induced hardening effects. The results of CLAM steel specimens show similar trend in microhardness and microstructure changes with irradiation dose, compared to F82H/Optimax-A steels irradiated in STIP-I/II. Defects and helium bubbles were observed in all specimens, even at a very low dose of 5.4 dpa. For defects and bubbles, the mean size and number density increased with increasing irradiation dose to 13 dpa, and then the mean size increased and number density decreased with the increasing irradiation dose to 20.8 dpa.

  6. Microstructure and microhardness of CLAM steel irradiated up to 20.8 dpa in STIP-V

    Science.gov (United States)

    Peng, Lei; Ge, Hongen; Dai, Yong; Huang, Qunying; Ye, Minyou

    2016-01-01

    Specimens of China low activation martensitic (CLAM) steel were irradiated in the fifth experiment of SINQ target irradiation program (STIP-V) up to 20.8 dpa/1564 appm He. Microhardness measurements and transmission electron microscope (TEM) observations have been performed to investigate irradiation induced hardening effects. The results of CLAM steel specimens show similar trend in microhardness and microstructure changes with irradiation dose, compared to F82H/Optimax-A steels irradiated in STIP-I/II. Defects and helium bubbles were observed in all specimens, even at a very low dose of 5.4 dpa. For defects and bubbles, the mean size and number density increased with increasing irradiation dose to 13 dpa, and then the mean size increased and number density decreased with the increasing irradiation dose to 20.8 dpa.

  7. Evaluation of Ion Irradiation Behavior of ODS Alloys

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Jin Sung; Kim, Min Chul; Hong, Jun Hwa; Han, Chang Hee; Chang, Young Mun; Bae, Chang Soo; Bae, Yoon Young; Chang, Moon Hee

    2006-08-15

    FM steel (Grade 92) and ODS alloy(MA956) specimens were ion irradiated with 122 MeV Ne ions. Irradiation temperatures were about 450 and 550 .deg. C and the peak dose was 1, 5, and 10 dpa. Cross-sectional TEM samples were prepared by the electrolytic Ni-plating after pre-treatment of the irradiated specimens. Irradiation cavities in FM steel and ODS alloy specimens were not much different in size; about 20 nm in diameter in both specimens irradiated at around 450 .deg. C. However, the size distribution of cavities in FM steel specimens was broader than that in ODS alloy specimen, indicating that the cavity growth probably via coalescence). It was noticeable that the location and the preferential growth of the cavities in FM steel specimens: cavities on the PAGB (prior austenite grain boundary) was significantly larger than those within the grains. This could be an important issue for the mechanical properties, especially high temperature creep, fracture toughness, and so on. The dependency of the dose threshold and swelling on the ratio of the inert gas concentration/dpa was analysed for the various irradiation source, including He, Ne, Fe/He, and fast neutron, and the empirical correlation was established.

  8. Experimental studies of irradiated and hydrogen implantation damaged reactor steels

    Energy Technology Data Exchange (ETDEWEB)

    Slugeň, Vladimír, E-mail: vladimir.slugen@stuba.sk; Pecko, Stanislav; Sojak, Stanislav

    2016-01-15

    Radiation degradation of nuclear materials can be experimentally simulated via ion implantation. In our case, German reactor pressure vessel (RPV) steels were studied by positron annihilation lifetime spectroscopy (PALS). This unique non-destructive method can be effectively applied for the evaluation of microstructural changes and for the analysis of degradation of reactor steels due to neutron irradiation and proton implantation. Studied specimens of German reactor pressure vessel steels are originally from CARINA/CARISMA program. Eight specimens were measured in as-received state and two specimens were irradiated by neutrons in German experimental reactor VAK (Versuchsatomkraftwerk Kahl) in the 1980s. One of the specimens which was in as-received and neutron irradiated condition was also used for simulation of neutron damage by hydrogen nuclei implantation. Defects with the size of about 1–2 vacancies with relatively small contribution (with intensity on the level of 20–40 %) were observed in “as-received” steels. A significant increase in the size of the induced defects due to neutron damage was observed in the irradiated specimens resulting in 2–3 vacancies. The size and intensity of defects reached a similar level as in the specimens irradiated in the nuclear reactor due to the implantation of hydrogen ions with energies of 100 keV (up to the depth <500 nm).

  9. Experimental studies of irradiated and hydrogen implantation damaged reactor steels

    Science.gov (United States)

    Slugeň, Vladimír; Pecko, Stanislav; Sojak, Stanislav

    2016-01-01

    Radiation degradation of nuclear materials can be experimentally simulated via ion implantation. In our case, German reactor pressure vessel (RPV) steels were studied by positron annihilation lifetime spectroscopy (PALS). This unique non-destructive method can be effectively applied for the evaluation of microstructural changes and for the analysis of degradation of reactor steels due to neutron irradiation and proton implantation. Studied specimens of German reactor pressure vessel steels are originally from CARINA/CARISMA program. Eight specimens were measured in as-received state and two specimens were irradiated by neutrons in German experimental reactor VAK (Versuchsatomkraftwerk Kahl) in the 1980s. One of the specimens which was in as-received and neutron irradiated condition was also used for simulation of neutron damage by hydrogen nuclei implantation. Defects with the size of about 1-2 vacancies with relatively small contribution (with intensity on the level of 20-40 %) were observed in "as-received" steels. A significant increase in the size of the induced defects due to neutron damage was observed in the irradiated specimens resulting in 2-3 vacancies. The size and intensity of defects reached a similar level as in the specimens irradiated in the nuclear reactor due to the implantation of hydrogen ions with energies of 100 keV (up to the depth <500 nm).

  10. Report on FY16 Low-dose Metal Fuel Irradiation and PIE

    Energy Technology Data Exchange (ETDEWEB)

    Edmondson, Philip D.

    2016-09-01

    This report gives an overview of the efforts into the low-dose metal fuel irradiation and PIE as part of the Fuel Cycle Research & Development (FCRD) Advanced Fuels Campaign (AFC) milestone M3FT-16OR020303031. The current status of the FCT and FCRP irradiation campaigns are given including a description of the materials that have been irradiated, analysis of the passive temperature monitors, and the initial PIE efforts of the fuel samples.

  11. Proton irradiation for hepatocellular carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Matsuzaki, Yasushi; Chiba, Shunya [Tsukuba Univ., Ibaraki (Japan). Inst. of Clinical Medicine; Tanaka, Naomi

    1999-02-01

    A curative effect of high dose proton irradiation for hepatoma was investigated. In cases of single nodular type HCC, radiation field was limited to tumor, and in cases of multi nodular type HCC, irradiation was also fractionated. An average dose of radiation was 4 Gy/time, average times were 16, and an average total dose was 72 Gy. Tumor size reduction rate at 6 months after proton irradiation (123 cases) was CR (17.9%), PR (52.0%), NC (29.3%) and PD (0.8%). And the reduction rate of tumor size in monotherapy cases was 100% (after 3 weeks), 96% (after 1 year) and 88% (after 2 years). The local control rate was 99.1% (after 1 year) and 91.4% (after 3-5 years). AFP value significantly decreased from 571.0{+-}1266.6 ng/ml before radiation to 145.4{+-}346.3 ng/ml after radiation (p<0.0005). The recurrence after radiation occurred more at outside of radiation field, significantly. Indication basis of proton irradiation was showed in this article. Because selective radiation is possible, the proton irradiation should be optimum therapy in specific carcinomas of deep organ. (K.H.)

  12. Acclimation to a dynamic irradiance regime changes excessive irradiance sensitivity of Emiliania huxleyi and Thalassiosira weissflogii

    OpenAIRE

    van De Poll, Willem H.; Visser, Ronald J. W.; Buma, Anita G. J.

    2007-01-01

    Effects of fluctuating irradiance regimes on excessive photosynthetically active radiation (PAR) and ultraviolet (UV) radiation sensitivity were assessed for Emiliania huxleyi (Lohman) and Thalassiosira weissflogii (Grunow) Fryxell and Hasle. Cultures acclimated to low irradiance were subjected to two irradiance regimes of equal daily dose: dynamic irradiance simulating vertical mixing within the water column and constant irradiance. For each regime two irradiance levels were studied. Growth ...

  13. Data acquisition system for light-ion irradiation creep experiment.

    Energy Technology Data Exchange (ETDEWEB)

    Hendrick, P.L.; Whitaker, T.J.

    1979-07-01

    Software was developed for a PDP11V/03-based data acquisition system to support the Light-Ion Irradiation Creep Experiment installed at the University of Washington Tandem Van de Graaff Accelerator. The software consists of a real-time data acquisition and storage program, DAC04, written in assembly language. This program provides for the acquisition of up to 30 chennels at 100 Hz, data averaging before storage on disk, alarming, data table display, and automatic disk switching. All analog data are acquired via an analog-to-digital converter subsystem having a resolution of 14 bits, a maximum throughput of 20 kHz, and an overall system accuracy of +-0.01%. These specifications are considered essential for the long-term measurement of irradiation creep strains and temperatures during the light-ion bombardment of irradiation creep specimens. The software package developed also contains a collection of FORTRAN programs designed to monitor a test while in progress. These programs use the foreground/background feature of the RT-11 operating system. The background programs provide a variety of services. The program, GRAFTR, allows transient data (i.e., prior to averaging) to be graphed at the graphics terminal. The program, GRAFAV, allows averaged data to be read from disk and displayed graphically at the terminal. The program, TYPAV, reads averaged data from disk and displays it at the terminal in tabular form. Other programs allow text messages to be written to disk, read from disk, and allow access to DAC04 initialization data. 5 figures, 18 tables.

  14. Dosimetric evaluation of three adaptive strategies for prostate cancer treatment including pelvic lymph nodes irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Cantin, Audrey; Gingras, Luc; Archambault, Louis, E-mail: louis.archambault@phy.ulaval.ca [Département de Physique, de génie Physique et d’optique et Centre de Recherche sur le Cancer, Université Laval, Québec, Québec G1V 0A6, Canada and Département de Radio-Oncologie et Centre de Recherche du CHU de Québec, CHU de Québec—Université Laval, 11 côte du Palais, Québec, Québec G1R 2J6 (Canada); Lachance, Bernard; Foster, William [Département de Radio-Oncologie et Centre de Recherche du CHU de Québec, CHU de Québec—Université Laval, 11 côte du Palais, Québec, Québec G1R 2J6 (Canada); Goudreault, Julie [Département de Radio-Oncologie et Centre de Recherche du CHU de Québec, CHU de Québec—Université Laval, 11 côte du Palais, Québec, Québec G1R 2J6, Canada and Département de Radio-Oncologie, CSSS de Gatineau–Hôpital de Gatineau, 909 Boulevard La Vérendrye, Gatineau, Québec J8P 7H2 (Canada)

    2015-12-15

    Purpose: The movements of the prostate relative to the pelvic lymph nodes during intensity-modulated radiation therapy treatment can limit margin reduction and affect the protection of the organs at risk (OAR). In this study, the authors performed an analysis of three adaptive treatment strategies that combine information from both bony and gold marker registrations. The robustness of those treatments against the interfraction prostate movements was evaluated. Methods: A retrospective study was conducted on five prostate cancer patients with 7–13 daily cone-beam CTs (CBCTs). The clinical target volumes (CTVs) consisting of pelvic lymph nodes, prostate, and seminal vesicles as well as the OARs were delineated on each CBCT and the initial CT. Three adaptive strategies were analyzed. Two of these methods relied on a two-step patient positioning at each fraction. First step: a bony registration was used to deliver the nodal CTV prescription. Second step: a gold marker registration was then used either to (1) complete the dose delivered to the prostate (complement); (2) or give almost the entire prescription to the prostate with a weak dose gradient between the targets to compensate for possible motions (gradient). The third method (COR) used a pool of precalculated plans based on images acquired at previous treatment fractions. At each new fraction, a plan is selected from that pool based on the daily position of prostate center-of-mass. The dosimetric comparison was conducted and results are presented with and without the systematic shift in the prostate position on the CT planning. The adaptive strategies were compared to the current clinical standard where all fractions are treated with the initial nonadaptive plan. Results: The minimum daily prostate D{sub 95%} is improved by 2%, 9%, and 6% for the complement, the gradient, and the COR approaches, respectively, compared to the nonadaptive method. The average nodal CTV D{sub 95%} remains constant across the strategies, except for the gradient approach where a reduction of 7% is observed. However, a correction of the systematic shift reduced the problem, and the adaptive strategies remain robust against the prostate movement across the fraction. The bladder V{sub 55Gy} is reduced by 35% on average for the adaptive strategies. Conclusions: Because they offer increased CTV coverage and OAR sparing, adaptive methods may be suitable candidates for simple and efficient adaptive treatment strategies for prostate cancer. Margin reduction and systematic error correction in the prostate position improve the protection of the OAR and the dose coverage. A cumulative dose to simulate a complete treatment would show real effects and allow a better comparison between each method.

  15. Using AERONET to complement irradiance networks on the validation of satellite-based estimations

    Science.gov (United States)

    Oumbe, A.; Bru, H.; Ghedira, H.; Chiesa, M.; Blanc, P.; Wald, L.

    2012-12-01

    Long-term measurements of surface solar irradiance (SSI) are essential for predicting the production of solar energy conversion systems. Ground-based SSIs are also needed for validation and calibration of models which convert satellite images into down-welling irradiances. Unfortunately, well-controlled data are publicly available for only a limited number of locations, especially when it comes to beam normal irradiance (BNI). In the Middle East particularly, there is only one publicly available research-class station: the Sede Boqer station, monitored by the BSRN (Baseline Surface Radiation Network). Thus, estimations of SSIs have been so far difficult to validate in this region. Besides irradiance networks, AERONET (Aerosol Robotic network) program provides long-term and public accessible sun photometer measurements. Its main goal is to provide validation data for satellite retrievals of aerosol optical properties. Various atmospheric properties are measured: aerosol optical depth at several wavelengths, water vapor amount, Angstrom coefficients. These data can be utilized for computation of SSI in cloudless sky by means of a radiative transfer model (RTM). The appropriate conversion of AERONET atmospheric properties into irradiances would provide additional in-situ irradiance data. In this work, we select the AERONET data which are relevant for irradiance calculation, compute the direct and global irradiances using the RTM LibRadTran and validate the outcomes with nearest actual irradiance measurements. The comparisons are made in the Middle East region. At Sede Boqer where AERONET and BSRN measurements are simultaneously available, the standard-deviation obtained is only 6% for BNI and 5% for GHI (global horizontal irradiance) between the computed and the measured hourly mean irradiances (see the attached figure). When the AERONET and BSRN stations considered are 100 km away, the standard-deviation between actually measured and AERONET-derived irradiances

  16. Thalidomide Ameliorates Inflammation and Vascular Injury but Aggravates Tubular Damage in the Irradiated Mouse Kidney

    Energy Technology Data Exchange (ETDEWEB)

    Scharpfenecker, Marion, E-mail: m.scharpfenecker@nki.nl [Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam (Netherlands); Floot, Ben [Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam (Netherlands); Russell, Nicola S. [Division of Radiotherapy, The Netherlands Cancer Institute, Amsterdam (Netherlands); Coppes, Rob P. [Departments of Radiation Oncology and Cell Biology, University Medical Centre Groningen, University of Groningen, Groningen (Netherlands); Stewart, Fiona A. [Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam (Netherlands)

    2014-07-01

    Purpose: The late side effects of kidney irradiation include vascular damage and fibrosis, which are promoted by an irradiation-induced inflammatory response. We therefore treated kidney-irradiated mice with the anti-inflammatory and angiogenesis-modulating drug thalidomide in an attempt to prevent the development of late normal tissue damage and radiation nephropathy in the mouse kidney. Methods and Materials: Kidneys of C57Bl/6 mice were irradiated with a single dose of 14 Gy. Starting from week 16 after irradiation, the mice were fed with thalidomide-containing chow (100 mg/kg body weight/day). Gene expression and kidney histology were analyzed at 40 weeks and blood samples at 10, 20, 30, and 40 weeks after irradiation. Results: Thalidomide improved the vascular structure and vessel perfusion after irradiation, associated with a normalization of pericyte coverage. The drug also reduced infiltration of inflammatory cells but could not suppress the development of fibrosis. Irradiation-induced changes in hematocrit and blood urea nitrogen levels were not rescued by thalidomide. Moreover, thalidomide worsened tubular damage after irradiation and also negatively affected basal tubular function. Conclusions: Thalidomide improved the inflammatory and vascular side effects of kidney irradiation but could not reverse tubular toxicity, which probably prevented preservation of kidney function.

  17. Effects of gamma irradiation on the yields of volatile extracts of Angelica gigas Nakai

    Science.gov (United States)

    Seo, Hye-Young; Kim, Jun-Hyoung; Song, Hyun-Pa; Kim, Dong-Ho; Byun, Myung-Woo; Kwon, Joog-Ho; Kim, Kyong-Su

    2007-11-01

    The study was carried out to determine the effects of gamma irradiation on the volatile flavor components including essential oils, of Angelica gigas Nakai. The volatile organic compounds from non- and irradiated A. gigas Nakai at doses of 1, 3, 5, 10 and 20 kGy were extracted by a simultaneous steam distillation and extraction (SDE) method and identified by GC/MS analysis. A total of 116 compounds were identified and quantified from non- and irradiated A. gigas Nakai. The major volatile compounds were identified 2,4,6-trimethyl heptane, α-pinene, camphene, α-limonene, β-eudesmol, α-murrolene and sphatulenol. Among these compounds, the amount of essential oils in non-irradiated sample were 77.13%, and the irradiated samples at doses of 1, 3, 5, 10 and 20 kGy were 84.98%, 83.70%, 83.94%, 82.84% and 82.58%, respectively. Oxygenated terpenes such as β-eudesmol, α-eudesmol, and verbenone were increased after irradiation but did not correlate with the irradiation dose. The yields of active substances such as essential oil were increased after irradiation; however, the yields of essential oils and the irradiation dose were not correlated. Thus, the profile of composition volatiles of A. gigas Nakai did not change with irradiation.

  18. Nasopharyngeal radium irradiation: The lessons of history.

    Science.gov (United States)

    Graamans, Kees

    2017-02-01

    In the Netherlands, nasopharyngeal radium irradiation was started in 1945. The indications included refractory symptoms of otitis media with effusion and other adenoid-related disorders after adenoidectomy. It was considered a safe and effective therapy. Its use decreased sharply in 1958, following a worldwide media avalanche around the dramatic events in the treatment of a 5-year-old child in Utrecht, enhancing the widespread fear of radioactivity. This case history illustrates the powerful role of the media in medical decision-making. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  19. Intrinsic Tamper Indicating Device (TID) Program

    Energy Technology Data Exchange (ETDEWEB)

    Haag, W.E.

    1996-09-01

    The Los Alamos National Laboratory (LANL) Intrinsic Tamper Indicating Device (TID) Program has recently been developed in conjunction with the regular LANL TID Program to assist groups who perform measurements using sealed sources or store difficult-to-measure items. The program was then expanded to include other types of sealed sources and items processed for long-term storage in the Nuclear Material Packaging and Repackaging Program. The Intrinsic TID Program encompasses both Special Nuclear Material (SNM) and Nuclear Material (NM) items that have intrinsic characteristics that would immediately indicate tampering upon visual inspection. Items determined to be intrinsically sealed do not need to be sealed with authorized tamper indicating devices. Under the program, an identified intrinsic item receives the same safeguards credits as other tamper-sealed items already in the TID Program. The major benefits of the Intrinsic TID Program include reducing verification measurements on intrinsically identified inventory items and reducing exposure to operators working in highly irradiated environments. Intrinsic TIDs should be combined with other safeguards requirements, and items should have defensible measurements as well as visual inspections. Several groups at LANL are already implementing the program and providing feedback so that we can tailor it to better meet the customers` needs.

  20. AGC 2 Irradiation Creep Strain Data Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Windes, William E. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rohrbaugh, David T. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Swank, W. David [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-01

    The Advanced Reactor Technologies Graphite Research and Development Program is conducting an extensive graphite irradiation experiment to provide data for licensing of a high temperature reactor (HTR) design. In past applications, graphite has been used effectively as a structural and moderator material in both research and commercial high temperature gas cooled reactor designs. Nuclear graphite H-451, used previously in the United States for nuclear reactor graphite components, is no longer available. New nuclear graphite grades have been developed and are considered suitable candidates for new HTR reactor designs. To support the design and licensing of HTR core components within a commercial reactor, a complete properties database must be developed for these current grades of graphite. Quantitative data on in service material performance are required for the physical, mechanical, and thermal properties of each graphite grade, with a specific emphasis on data accounting for the life limiting effects of irradiation creep on key physical properties of the HTR candidate graphite grades. Further details on the research and development activities and associated rationale required to qualify nuclear grade graphite for use within the HTR are documented in the graphite technology research and development plan.

  1. AGC 2 Irradiated Material Properties Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rohrbaugh, David Thomas [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-05-01

    The Advanced Reactor Technologies Graphite Research and Development Program is conducting an extensive graphite irradiation experiment to provide data for licensing of a high temperature reactor (HTR) design. In past applications, graphite has been used effectively as a structural and moderator material in both research and commercial high temperature gas cooled reactor designs. , Nuclear graphite H 451, used previously in the United States for nuclear reactor graphite components, is no longer available. New nuclear graphite grades have been developed and are considered suitable candidates for new HTR reactor designs. To support the design and licensing of HTR core components within a commercial reactor, a complete properties database must be developed for these current grades of graphite. Quantitative data on in service material performance are required for the physical, mechanical, and thermal properties of each graphite grade, with a specific emphasis on data accounting for the life limiting effects of irradiation creep on key physical properties of the HTR candidate graphite grades. Further details on the research and development activities and associated rationale required to qualify nuclear grade graphite for use within the HTR are documented in the graphite technology research and development plan.

  2. A new generation of X ray irradiators for insect sterilization.

    Science.gov (United States)

    Mastrangelo, T; Parker, A G; Jessup, A; Pereira, R; Orozco-Dávila, D; Islam, A; Dammalage, T; Walder, J M M

    2010-02-01

    Recent fears of terrorism have provoked an increase in delays and denials of transboundary shipments of radioisotopes. This represents a serious constraint to sterile insect technique (SIT) programs around the world as they rely on the use of ionizing radiation from radioisotopes for insect sterilization. To validate a novel X ray irradiator, a series of studies on Ceratitis capitata (Wiedemann) and Anastrepha fraterculus (Wiedemann) (Diptera: Tephritidae) were carried out, comparing the relative biological effectiveness (RBE) between X rays and traditional gamma radiation from 60Co. Male C. capitata pupae and pupae of both sexes of A. fraterculus, both 24-48 h before adult emergence, were irradiated with doses ranging from 15 to 120 Gy and 10-70 Gy, respectively. Estimated mean doses of 91.2 Gy of X and 124.9 Gy of gamma radiation induced 99% sterility in C. capitata males. Irradiated A. fraterculus were 99% sterile at approximately 40-60 Gy for both radiation treatments. Standard quality control parameters and mating indices were not significantly affected by the two types of radiation. The RBE did not differ significantly between the tested X and gamma radiation, and X rays are as biologically effective for SIT purposes as gamma rays are. This work confirms the suitability of this new generation of X ray irradiators for pest control programs that integrate the SIT.

  3. Irradiation test of high density Si material

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Man Soon; Choo, Kee Nam; Lee, Chul Yong; Yang, Seong Woo; Shim, Kyue Taek; Park, Sang Jun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-10-15

    The feasibility of irradiation test for the high-density Si material entrusted by Guju Inc. was reviewed. The high density Si material is used for a sealing of the penetration holes of piping at the nuclear power plants. The irradiation test was performed and the density changes between before and after irradiation test were measured. The irradiation tests were performed 2 times for 1 day and 20 days at IP 4 hole of HANARO. The 3 Si specimens irradiated were without flaws and the density changes after irradiation were successfully measured. The result satisfies the requirement of the design specification.

  4. Fission Product Inventory and Burnup Evaluation of the AGR-2 Irradiation by Gamma Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Harp, Jason Michael [Idaho National Lab. (INL), Idaho Falls, ID (United States); Stempien, John Dennis [Idaho National Lab. (INL), Idaho Falls, ID (United States); Demkowicz, Paul Andrew [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    Gamma spectrometry has been used to evaluate the burnup and fission product inventory of different components from the US Advanced Gas Reactor Fuel Development and Qualification Program's second TRISO-coated particle fuel irradiation test (AGR-2). TRISO fuel in this irradiation included both uranium carbide / uranium oxide (UCO) kernels and uranium oxide (UO2) kernels. Four of the 6 capsules contained fuel from the US Advanced Gas Reactor program, and only those capsules will be discussed in this work. The inventories of gamma-emitting fission products from the fuel compacts, graphite compact holders, graphite spacers and test capsule shell were evaluated. These data were used to measure the fractional release of fission products such as Cs-137, Cs-134, Eu-154, Ce-144, and Ag-110m from the compacts. The fraction of Ag-110m retained in the compacts ranged from 1.8% to full retention. Additionally, the activities of the radioactive cesium isotopes (Cs-134 and Cs-137) have been used to evaluate the burnup of all US TRISO fuel compacts in the irradiation. The experimental burnup evaluations compare favorably with burnups predicted from physics simulations. Predicted burnups for UCO compacts range from 7.26 to 13.15 % fission per initial metal atom (FIMA) and 9.01 to 10.69 % FIMA for UO2 compacts. Measured burnup ranged from 7.3 to 13.1 % FIMA for UCO compacts and 8.5 to 10.6 % FIMA for UO2 compacts. Results from gamma emission computed tomography performed on compacts and graphite holders that reveal the distribution of different fission products in a component will also be discussed. Gamma tomography of graphite holders was also used to locate the position of TRISO fuel particles suspected of having silicon carbide layer failures that lead to in-pile cesium release.

  5. Fission Product Inventory and Burnup Evaluation of the AGR-2 Irradiation by Gamma Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Harp, Jason M.; Demkowicz, Paul A.; Stempien, John D.

    2016-11-01

    Gamma spectrometry has been used to evaluate the burnup and fission product inventory of different components from the US Advanced Gas Reactor Fuel Development and Qualification Program's second TRISO-coated particle fuel irradiation test (AGR-2). TRISO fuel in this irradiation included both uranium carbide / uranium oxide (UCO) kernels and uranium oxide (UO2) kernels. Four of the 6 capsules contained fuel from the US Advanced Gas Reactor program, and only those capsules will be discussed in this work. The inventories of gamma-emitting fission products from the fuel compacts, graphite compact holders, graphite spacers and test capsule shell were evaluated. These data were used to measure the fractional release of fission products such as Cs-137, Cs-134, Eu-154, Ce-144, and Ag-110m from the compacts. The fraction of Ag-110m retained in the compacts ranged from 1.8% to full retention. Additionally, the activities of the radioactive cesium isotopes (Cs-134 and Cs-137) have been used to evaluate the burnup of all US TRISO fuel compacts in the irradiation. The experimental burnup evaluations compare favorably with burnups predicted from physics simulations. Predicted burnups for UCO compacts range from 7.26 to 13.15 % fission per initial metal atom (FIMA) and 9.01 to 10.69 % FIMA for UO2 compacts. Measured burnup ranged from 7.3 to 13.1 % FIMA for UCO compacts and 8.5 to 10.6 % FIMA for UO2 compacts. Results from gamma emission computed tomography performed on compacts and graphite holders that reveal the distribution of different fission products in a component will also be discussed. Gamma tomography of graphite holders was also used to locate the position of TRISO fuel particles suspected of having silicon carbide layer failures that lead to in-pile cesium release.

  6. Solar Indices - Solar Irradiance

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Collection includes a variety of indices related to solar activity contributed by a number of national and private solar observatories located worldwide. This...

  7. Cell proliferation in lymphoid tissue and the seminiferous epithelium under continuous low level irradiation. Final report, 1 June 1967 to 15 July 1973

    Energy Technology Data Exchange (ETDEWEB)

    Fabrikant, J I

    1978-10-19

    The scientific scope and primary objectives of the research program concern investigations on (1) the kinetics of cellular proliferation and differentiation in the immunohematopoietic tissues and the reproductive tissues, and (2) the cellular response and cell population kinetics of these renewal tissues of the body under the stress of continuous low level irradiation. The directions and objectives of the research program have been continually broadened to include investigations on (1) the dynamics of the cellular and humoral immune responses, (2) interactions of host-defense mechanisms, (3) the cell proliferation kinetics in the ovary, and (4) cellular control mechanisms and human tumor cell kinetics.

  8. Notes on irradiation of neodymium

    Energy Technology Data Exchange (ETDEWEB)

    Woods, W.K.

    1966-06-07

    The fission product, promethium-147, would be much more desirable as a heat-producing radioisotope if it were not in such short supply. C.A. Rohrmann`s chart ``Characteristics of Radioisotopic Heat Sources`` lists the annual availability of Pm-147 as 5-5 kw, corresponding to about 17 kg. Hence, consideration has been given to irradiation of neodymium-146 in order to augment the supply of Pm-147, A method for separating Nd-146 from other neodymium isotopes does not exist today. This memorandum presents the results of a brief look at the irradiation of mixed neodymium isotopes which are available without isotopic separation.

  9. Significance of irradiation of blood

    Energy Technology Data Exchange (ETDEWEB)

    Sekine, Hiroshi; Gotoh, Eisuke; Mochizuki, Sachio (Jikei Univ., Tokyo (Japan). School of Medicine)

    1992-10-01

    Many reports of fatal GVHD occurring in non-immunocompromised patients after blood transfusion have been published in Japan. One explantation is that transfused lymphocytes were simulated and attack the recipient organs recognized as HLA incompatible. That is so called 'one-way matching'. To reduce the risk of post-transfusion GVHD, one of the most convenient methods is to irradiate the donated blood at an appropriate dose for inactivation of lymphocytes. Because no one knows about the late effect of irradiated blood, it is necessary to make the prospective safety control. (author).

  10. Including Students with Visual Impairments: Softball

    Science.gov (United States)

    Brian, Ali; Haegele, Justin A.

    2014-01-01

    Research has shown that while students with visual impairments are likely to be included in general physical education programs, they may not be as active as their typically developing peers. This article provides ideas for equipment modifications and game-like progressions for one popular physical education unit, softball. The purpose of these…

  11. Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the Long-Term Care Hospital Prospective Payment System Policy Changes and Fiscal Year 2016 Rates; Revisions of Quality Reporting Requirements for Specific Providers, Including Changes Related to the Electronic Health Record Incentive Program; Extensions of the Medicare-Dependent, Small Rural Hospital Program and the Low-Volume Payment Adjustment for Hospitals. Final rule; interim final rule with comment period.

    Science.gov (United States)

    2015-08-17

    We are revising the Medicare hospital inpatient prospective payment systems (IPPS) for operating and capital related costs of acute care hospitals to implement changes arising from our continuing experience with these systems for FY 2016. Some of these changes implement certain statutory provisions contained in the Patient Protection and Affordable Care Act and the Health Care and Education Reconciliation Act of 2010 (collectively known as the Affordable Care Act), the Pathway for Sustainable Growth Reform(SGR) Act of 2013, the Protecting Access to Medicare Act of 2014, the Improving Medicare Post-Acute Care Transformation Act of 2014, the Medicare Access and CHIP Reauthorization Act of 2015, and other legislation. We also are addressing the update of the rate-of-increase limits for certain hospitals excluded from the IPPS that are paid on a reasonable cost basis subject to these limits for FY 2016.As an interim final rule with comment period, we are implementing the statutory extensions of the Medicare dependent,small rural hospital (MDH)Program and changes to the payment adjustment for low-volume hospitals under the IPPS.We also are updating the payment policies and the annual payment rates for the Medicare prospective payment system (PPS) for inpatient hospital services provided by long-term care hospitals (LTCHs) for FY 2016 and implementing certain statutory changes to the LTCH PPS under the Affordable Care Act and the Pathway for Sustainable Growth Rate (SGR) Reform Act of 2013 and the Protecting Access to Medicare Act of 2014.In addition, we are establishing new requirements or revising existing requirements for quality reporting by specific providers (acute care hospitals,PPS-exempt cancer hospitals, and LTCHs) that are participating in Medicare, including related provisions for eligible hospitals and critical access hospitals participating in the Medicare Electronic Health Record (EHR)Incentive Program. We also are updating policies relating to the

  12. Final Report on MEGAPIE Target Irradiation and Post-Irradiation Examination

    Energy Technology Data Exchange (ETDEWEB)

    Yong, Dai [Paul Scherrer-Institut (Switzerland)

    2015-06-30

    Megawatt pilot experiment (MEGAPIE) was successfully performed in 2006. One of the important goals of MEGAPIE is to understand the behaviour of structural materials of the target components exposed to high fluxes of high-energy protons and spallation neutrons in flowing LBE (liquid lead-bismuth eutectic) environment by conducting post-irradiation examination (PIE). The PIE includes four major parts: non-destructive test, radiochemical analysis of production and distribution of radionuclides produced by spallation reaction in LBE, analysis of LBE corrosion effects on structural materials, T91 and SS 316L steels, and mechanical testing of the T91 and SS 316L steels irradiated in the lower part of the target. The non-destructive test (NDT) including visual inspection and ultrasonic measurement was performed in the proton beam window area of the T91 calotte of the LBE container, the most intensively irradiated part of the MEGAPIE target. The visual inspection showed no visible failure and the ultrasonic measurement demonstrated no detectable change in thickness in the beam window area. Gamma mapping was also performed in the proton beam window area of the AlMg3 safety-container. The gamma mapping results were used to evaluate the accumulated proton fluence distribution profile, the input data for determining irradiation parameters. Radiochemical analysis of radionuclides produced by spallation reaction in LBE is to improve the understanding of the production and distribution of radionuclides in the target. The results demonstrate that the radionuclides of noble metals, 207Bi, 194Hg/Au are rather homogeneously distributed within the target, while radionuclides of electropositive elements are found to be deposited on the steel-LBE interface. The corrosion effect of LBE on the structural components under intensive irradiation was investigated by metallography. The results show that no evident corrosion damages. However, unexpected deep

  13. Statistical analysis using the Bayesian nonparametric method for irradiation embrittlement of reactor pressure vessels

    Science.gov (United States)

    Takamizawa, Hisashi; Itoh, Hiroto; Nishiyama, Yutaka

    2016-10-01

    In order to understand neutron irradiation embrittlement in high fluence regions, statistical analysis using the Bayesian nonparametric (BNP) method was performed for the Japanese surveillance and material test reactor irradiation database. The BNP method is essentially expressed as an infinite summation of normal distributions, with input data being subdivided into clusters with identical statistical parameters, such as mean and standard deviation, for each cluster to estimate shifts in ductile-to-brittle transition temperature (DBTT). The clusters typically depend on chemical compositions, irradiation conditions, and the irradiation embrittlement. Specific variables contributing to the irradiation embrittlement include the content of Cu, Ni, P, Si, and Mn in the pressure vessel steels, neutron flux, neutron fluence, and irradiation temperatures. It was found that the measured shifts of DBTT correlated well with the calculated ones. Data associated with the same materials were subdivided into the same clusters even if neutron fluences were increased.

  14. Effect of gamma-irradiation on the differential leukocyte count in fish Poecilia reticulata

    Directory of Open Access Journals (Sweden)

    Andrej Renčko

    2014-01-01

    Full Text Available The study investigated the effect of a single gamma-irradiation with a 60Co source at a dose of 20 Gy (1.05 Gy/min on the guppy Poecilia reticulata (females, n = 60, which has not been determined before in this fish. We observed food intake, clinical symptoms, pathological-anatomical and histological changes and differential leukocyte count in the irradiated guppies compared to the control ones. In the first days, timidity and lethargy were observed. The most prominent clinical symptoms observed were exophthalmia, emaciation and intravital haemorrhages. Livers of irradiated guppies were characterized by hepatic steatosis. Leukogram determinations were carried out on days 3, 7, 10, 15, and 20. Relative lymphopaenia was observed in irradiated fish and the mean relative monocyte count in irradiated guppies increased from 8.7 to 20.6 within 3 days. Other important values obtained from the leukogram included relative neutropaenia, eosinopaenia and basopaenia, observed on day 3 after irradiation.

  15. Morphological characterization of the reproductive system of irradiated Anastrepha fraterculus

    Energy Technology Data Exchange (ETDEWEB)

    Bartolucci, Andrea, E-mail: andreabartolucci@iscamen.com.a [Instituto de Sanidad y Calidad Agropecuaria de Mendoza (ISCAMEN), Mendoza (Argentina); Vera, M. Teresa [Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), (Argentina); Yusef, Veronica [Comision Nacional de Energia Atomica (Argentina). Centro Atomico Ezeiza; Oviedo, Andrea [Estacion Experimental Agroindustrial Obispo Colombres (EEAOC), Tucuman (Argentina)

    2006-07-01

    Field identification of released sterile insects is a major issue for eradication and suppression programs. Irradiated flies are normally identified by the presence of a fluorescent dye. When a fly lacks fluorescent dye, determination of gonadal state is necessary to identified between sterile or fertile flies. This is particularly relevant when population levels have decreased. Animal and identification is required to be as unequivocal as possible. Here we describe the reproductive system of irradiated Anastrepha fraterculus of different ages and we compare it with that of fertile flies in order to provide a diagnosis tool. Fertile and irradiated A. fraterculus were dissected from the day of emergence and until 15 days of age. Gross morphology was described and the gonads were measured. Germ cells were visualized in the testis. The reproductive systems of both males and females contained the same structures as other Anastrepha species. From day 1 to day 3, there were no detectable differences between irradiated and fertile males. The growing region encompassed half the testis total length and there was no free sperm in the seminal vesicle. On day 4 the presence of free sperm was seen in the seminal vesicle. At this stage irradiated males started differentiating from fertile ones: the growing region reduced in size and totally disappeared by day 11; sperm bundle zones occupied most of the testis; spermatids lost their triangular shape and sperm remained in the seminal vesicle without moving into the apical region. Testis length and width of irradiated males did not differ from fertile males. In females, the maturation of the ovaries involved a change in size that was more pronounced in the length of the ovary. This became noticeable at day 3. At this stage, the formation of yolk and the basal follicle began in fertile females and the oocyte had the same size as the trophocytes. From this point, the oocyte started growing. After day 8, the maturing oocyte reached

  16. Irradiação contralateral de força para a ativação do músculo tibial anterior em portadores da doença de Charcot-Marie-Tooth: efeitos de um programa de intervenção por FNP Contralateral force irradiation for the activation of tibialis anterior muscle in carriers of Charcot-Marie-Tooth disease: effect of PNF intervention program

    Directory of Open Access Journals (Sweden)

    Paula C. Meningroni

    2009-10-01

    Full Text Available OBJETIVO: Avaliar a resposta do músculo tibial anterior (TA após um protocolo de cinco semanas com irradiação contralateral de força através de diagonais de facilitação neuromuscular proprioceptiva (FNP em pacientes com polineuropatia desmielinizante associada à doença de Charcot-Marie-Tooth do tipo 1A (CMT-1A. MÉTODOS: Participaram deste estudo 12 pacientes, de ambos os sexos. Eles foram tratados em uma frequência de duas vezes por semana, durante cinco semanas. Em cada sessão, foram utilizadas as diagonais de Chopping, extensão-adução com rotação interna (EARI e flexão-abdução com rotação interna (FARI. As diagonais foram repetidas quatro vezes, em ambos os membros superiores e inferiores; cada diagonal tinha duração média de 6 segundos. Durante as execuções, a resposta muscular do TA foi registrada por um eletromiógrafo de superfície, desprezando-se os 2 segundos iniciais e finais de cada diagonal. A média dos valores de Root Mean Square (RMS das quatro repetições foi normalizada em porcentagem. Os dados iniciais e finais foram submetidos ao teste em t para amostras pareadas com valores de p significativos OBJECTIVE: To evaluate the response of the tibialis anterior (TA muscle following a five-week protocol with contralateral irradiation force through Proprioceptive Neuromuscular Facilitation (PNF diagonals in patients with demyelinating polyneuropathy associated with Charcot-Marie-Tooth disease type 1A (CMT-1A. METHODS: The study included 12 patients of both sexes. They were treated twice-weekly for 5 weeks. At each session, they performed the following diagonal patterns: chopping, extension-adduction with internal rotation (EAIR and flexion-abduction with internal rotation (FAIR. The diagonals were repeated four times, in both upper and lower limbs, with each repetition lasting six seconds on average. During execution, the response of the TA muscle was recorded by a surface electromyograph disregarding the

  17. Intercomparison of 51 radiometers for determining global horizontal irradiance and direct normal irradiance measurements

    Energy Technology Data Exchange (ETDEWEB)

    Habte, Aron; Sengupta, Manajit; Andreas, Afshin; Wilcox, Stephen; Stoffel, Thomas

    2016-08-01

    Accurate solar radiation measurements require properly installed and maintained radiometers with calibrations traceable to the World Radiometric Reference. This study analyzes the performance of 51 commercially available and prototype radiometers used for measuring global horizontal irradiances or direct normal irradiances. These include pyranometers, pyrheliometers, rotating shadowband radiometers, and a pyranometer with an internal shading mask deployed at the National Renewable Energy Laboratory's (NREL) Solar Radiation Research Laboratory. The radiometers in this study were deployed for one year (from April 1, 2011, through March 31, 2012), and their measurements were compared under clear-sky, partly cloudy, and mostly cloudy conditions to reference values of low estimated measurement uncertainties. The intent of this paper is to present a general overview of each radiometer's performance based on the instrumentation and environmental conditions available at NREL.

  18. Paternal irradiation perturbs the expression of circadian genes in offspring

    Energy Technology Data Exchange (ETDEWEB)

    Gomes, Andre M.G.F.; Barber, Ruth C.; Dubrova, Yuri E., E-mail: yed2@le.ac.uk

    2015-05-15

    Highlights: • We have analysed gene expression in the offspring of irradiated male mice. • CBA/Ca and BALB/c male mice were used in our study. • The pattern of gene expression was established in four tissues. • Expression of genes in involved in rhythmic process/circadian rhythm is compromised. • Our data may explain the phenomenon of transgenerational genomic instability. - Abstract: The circadian system represents a complex network which influences the timing of many biological processes. Recent studies have established that circadian alterations play an important role in the susceptibility to many human diseases, including cancer. Here we report that paternal irradiation in mice significantly affects the expression of genes involved in rhythmic processes in their first-generation offspring. Using microarrays, the patterns of gene expression were established for brain, kidney, liver and spleen samples from the non-exposed offspring of irradiated CBA/Ca and BALB/c male mice. The most over-represented categories among the genes differentially expressed in the offspring of control and irradiated males were those involved in rhythmic process, circadian rhythm and DNA-dependent regulation of transcription. The results of our study therefore provide a plausible explanation for the transgenerational effects of paternal irradiation, including increased transgenerational carcinogenesis described in other studies.

  19. Unintended cardiac irradiation during left-sided breast cancer radiotherapy.

    Science.gov (United States)

    Goody, R B; O'Hare, J; McKenna, K; Dearey, L; Robinson, J; Bell, P; Clarke, J; McAleer, J J A; O'Sullivan, J M; Hanna, G G

    2013-02-01

    Cardiac irradiation during left-sided breast radiotherapy may lead to deleterious cardiac side effects. Using image guided radiotherapy, it is possible to exclude the heart from treatment fields and monitor reproducibility of virtual simulation (VS) fields at treatment delivery using electronic portal imaging (EPI). Retrospectively, we evaluate the incidence of cardiac irradiation at VS and subsequent unintended cardiac irradiation during treatment. Patients receiving left-sided radiotherapy to the breast or chest wall, treated with a glancing photon field technique during a four-month period, were included. VS images and EPIs during radiotherapy delivery were visually assessed. The presence of any portion of the heart within the treatment field at VS or during treatment was recorded. Central lung distance and maximum heart distance were recorded. Of 128 patients, 45 (35.1%) had any portion of the heart within the planned treatment field. Of these, inclusion of the heart was clinically unavoidable in 25 (55.6%). Of those with no heart included in the treatment fields at VS, 41 (49.4%) had presence of the heart as assessed on EPI during treatment. Unintended cardiac irradiation during left-sided breast radiotherapy treatment occurs in a sizeable proportion of patients. Despite the use of three-dimensional computed tomography simulation and cardiac shielding, sizeable proportions of patients receiving left-sided breast cancer radiotherapy have unintended cardiac irradiation.

  20. Advanced Decontamination Technologies: Irradiation

    Science.gov (United States)

    Lee, Eun Joo; Ahn, Dong U.

    Bacterial food-borne illnesses account for an estimated 76 million cases, 325,000 hospitalizations, and 5,000 deaths each year in the United States (CDCP, 2005), and 5,300 food-borne outbreaks in Europe resulted in 5,330 hospitalizations and 24 deaths in 2005 (Aymerich, Picouet, & Monfort, 2008). Major food-borne pathogens of concern include Escherichia coli O157:H7, Campylobacter jejuni/coli, Salmonella spp., Listeria monocytogenes, Clostridium botulinum/perfringens, Staphylococcus aureus, Aeromonas hydrophylia, and Bacillus cereu, and spoilage microorganisms include Pseudomonas, Acinetobacter/Moraxella, Aeromonas, Alteromonas putrefaciens, Lactobacillus, and Brochothrix thermosphecta (Mead et al., 1999).

  1. Analysis and Experimental Qualification of an Irradiation Capsule Design for Testing Pressurized Water Reactor Fuel Cladding in the High Flux Isotope Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Kurt R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Howard, Richard H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Daily, Charles R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Petrie, Christian M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-09-01

    The Advanced Fuels Campaign within the Fuel Cycle Research and Development program of the Department of Energy Office of Nuclear Energy is currently investigating a number of advanced nuclear fuel cladding concepts to improve the accident tolerance of light water reactors. Alumina-forming ferritic alloys (e.g., FeCrAl) are some of the leading candidates to replace traditional zirconium alloys due to their superior oxidation resistance, provided no prohibitive irradiation-induced embrittlement occurs. Oak Ridge National Laboratory has developed experimental designs to irradiate thin-walled cladding tubes with representative pressurized water reactor geometry in the High Flux Isotope Reactor (HFIR) under relevant temperatures. These designs allow for post-irradiation examination (PIE) of cladding that closely resembles expected commercially viable geometries and microstructures. The experiments were designed using relatively inexpensive rabbit capsules for the irradiation vehicle. The simplistic designs combined with the extremely high neutron flux in the HFIR allow for rapid testing of a large test matrix, thus reducing the time and cost needed to advanced cladding materials closer to commercialization. The designs are flexible in that they allow for testing FeCrAl alloys, stainless steels, Inconel alloys, and zirconium alloys (as a reference material) both with and without hydrides. This will allow a direct comparison of the irradiation performance of advanced cladding materials with traditional zirconium alloys. PIE will include studies of dimensional change, microstructure variation, mechanical performance, etc. This work describes the capsule design, neutronic and thermal analyses, and flow testing that were performed to support the qualification of this new irradiation vehicle.

  2. Microstructural processes in irradiated materials

    Science.gov (United States)

    Byun, Thak Sang; Morgan, Dane; Jiao, Zhijie; Almer, Jonathan; Brown, Donald

    2016-04-01

    These proceedings contain the papers presented at two symposia, the Microstructural Processes in Irradiated Materials (MPIM) and Characterization of Nuclear Reactor Materials and Components with Neutron and Synchrotron Radiation, held in the TMS 2015, 144th Annual Meeting & Exhibition at Walt Disney World, Orlando, Florida, USA on March 15-19, 2015.

  3. Progress in food irradiation: Germany

    Energy Technology Data Exchange (ETDEWEB)

    Diehl, J.F.

    1982-11-01

    The report by the FRG deals with irradiation of foodstuffs, such as potatoes, onions, fish and meats, with gamma and X-rays and with radiochemical changes. Radioresistence is tested for in Salmonella. Wholesomeness studies and mutagenicity tests were carried out showing high losses in vitamins whereas long-lived, free radicals could be measured obtaining to dried material only.

  4. Inhomogeneous microstructural growth by irradiation

    DEFF Research Database (Denmark)

    Krishan, K.; Singh, Bachu Narain; Leffers, Torben

    1985-01-01

    In the present paper we discuss the development of heterogeneous microstructure for uniform irradiation conditions. It is shown that microstructural inhomogeneities on a scale of 0.1 μm can develop purely from kinematic considerations because of the basic structure of the rate equations used...

  5. Low-oxygen atmospheric treatment improves the performance of irradiation-sterilized male cactus moths used in SIT.

    Science.gov (United States)

    As part of Sterile Insect Technique (SIT) programs, irradiation can effectively induce sterility in insects by damaging genomic DNA. However, irradiation also induces other off-target side effects that reduce the quality and performance of sterilized males. Thus, treatments that reduce off-target ef...

  6. Neutron Irradiation Tests in Superfluid Helium of LHC Cryogenic Thermometers

    CERN Document Server

    Amand, J F; Junquera, T; Thermeau, J P

    1998-01-01

    For control and monitoring purposes, about 10,000 individually calibrated cryogenic temperature sensors will be installed along the 26.7 km LHC. In order to reduce maintenance constraints these sensor s should be as immune as possible to the high neutron fluence environment. For selecting the sensor to be used, a radiation hardness evaluation program at cryogenic conditions is being performed in an irradiation vault of the ISN SARA Cyclotron (Grenoble, France). The set-up is capable of simulating the whole life of a LHC thermometer: same total neutron dose (1015 n.cm-2), irradiation at low tempe rature (1.8 K) and thermal cycles. Bath temperature and sensor resistance are monitored on-line. This paper presents the latest results of this program.

  7. Center Innovation Fund: JSC CIF (also includes JSC IRAD) Program

    Data.gov (United States)

    National Aeronautics and Space Administration — JSC provides and applies its preeminent capabilities in science and technology to develop, operate, and integrate human exploration missions.  The Center...

  8. Program for reduction body mass and cellulite including aesthetic physiotherapy

    OpenAIRE

    Nikolovska, Lence

    2012-01-01

    The study monitored the effect of separate eating, ultrasonic cavitation, presoterapy, radio frequency and vibrating platform (GREEN PLATE) weight reduction, cellulite removal and improved psycho-emotional status. Perform 3 weekly treatments. In the course of three months were examined 45 overweight women and cellulite.

  9. Neutron irradiation effects on plasma facing materials

    Science.gov (United States)

    Barabash, V.; Federici, G.; Rödig, M.; Snead, L. L.; Wu, C. H.

    2000-12-01

    This paper reviews the effects of neutron irradiation on thermal and mechanical properties and bulk tritium retention of armour materials (beryllium, tungsten and carbon). For each material, the main properties affected by neutron irradiation are described and the specific tests of neutron irradiated armour materials under thermal shock and disruption conditions are summarized. Based on current knowledge, the expected thermal and structural performance of neutron irradiated armour materials in the ITER plasma facing components are analysed.

  10. The application of irradiation to phyto sanitary problems

    Energy Technology Data Exchange (ETDEWEB)

    Ross, R.T. [USDA/APHIS/PPQ. Department of Agriculture, Room 1630 Soagribg, 1400 Independence Ave. Sw. Mail Code Stop 3438, 20250 Washington D.C. (United States)

    1997-12-31

    The first formally adopted regulatory policy for irradiation as a phyto sanitary treatment in the United States was issued in 1989 and was based on Title 7 of the Code of Federal Regulations. These regulations authorized irradiation as a quarantine treatment for papayas intended for movement from the State of Hawaii to the continental United States (U.S.), Guam, Puerto Rico, and the U.S. Virgin Islands. This authorization was specific for commodity, place of origin, and program, but was designed for a complex of three fruit flies rather than a single pest. Routine commercial shipments were never realized under this regulation due to the lack of a treatment facility in Hawaii. However, the authorization has proven useful from the standpoint of beginning to establish policies for irradiation as a phyto sanitary treatment in the United States. The United States Department of Agriculture (USDA), Animal and Plant Health Inspection Service (APHIS), Plant Protection and Quarantine (PPQ) remains dedicated to using the most up-to-date, appropriate and least intrusive technology to provide quarantine security. The need for alternative treatments for pests mitigation systems is greater than ever. Global trade pressures and the possible loss of methyl bromide make it imperative that all practical treatment options be explored. Since 1989 irradiation treatment concepts have matured significantly. Technological advances, greater experience, and an increasingly larger body of research indicate that irradiation has important potential as a treatment for quarantine pest problems. It is in this light that PPQ is expanding its regulatory framework, is addressing irradiation treatment options, and is developing comprehensive policy statements intended to facilitate the development and formalization of new treatments for phyto sanitary applications. (Author)

  11. NANOSTRUCTURE PATTERNING UNDER ENERGETIC PARTICLE BEAM IRRADIATION

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Lumin [Regents of the University of Michigan; Lu, Wei [Regents of the University of Michigan

    2013-01-31

    understanding of fundamental scientific basis for the irradiation-induced self-organization processes. The fundamental physical mechanisms underlying ordered pattern formation, which include defect production and migration, ion sputtering, redeposition, viscous flow and diffusion, are investigated through a combination of modeling and in situ and ex-situ observations [3,9,11]. In addition, these nanostructured materials exhibit considerable improvement of optical properties [9,12,13]. For example, patterned Ge with a hexagonally ordered, honeycomb-like structure of nanoscale holes possesses a high surface area and a considerably blue-shifted energy gap [9], and oxidation of ordered Ga droplets shows noticeable enhancement of optical transmission [12]. This research has addressed nanopattern formation in a variety of materials under ion bombardment and provided a fundamental understanding of the dynamic mechanisms involved. In addition, have also stared to systematically investigate pattern formation under ion irradiation for more systems with varied experimental conditions and computation, including the collaboration with Dr. Veena Tikare of Sandia National Laboratory with a hybrid computation method at the ending this grant. A more detailed relationship between nanostructure formation and experimental conditions will be revealed with our continued efforts.

  12. Status of the NGNP Fuel Experiment AGR-2 Irradiated in the Advanced Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Blaine Grover

    2012-10-01

    The United States Department of Energy’s Next Generation Nuclear Plant (NGNP) Advanced Gas Reactor (AGR) Fuel Development and Qualification Program will be irradiating up to seven separate low enriched uranium (LEU) tri-isotopic (TRISO) particle fuel (in compact form) experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). These irradiations and fuel development are being accomplished to support development of the next generation reactors in the United States, and will be irradiated over the next several years to demonstrate and qualify new TRISO coated particle fuel for use in high temperature gas reactors. The goals of the irradiation experiments are to provide irradiation performance data to support fuel process development, to qualify fuel for normal operating conditions, to support development and validation of fuel performance and fission product transport models and codes, and to provide irradiated fuel and materials for post irradiation examination (PIE) and safety testing. The experiments, which will each consist of at least six separate capsules, will be irradiated in an inert sweep gas atmosphere with individual on-line temperature monitoring and control of each capsule. The sweep gas will also have on-line fission product monitoring on its effluent to track performance of the fuel in each individual capsule during irradiation. The first experiment (designated AGR-1) started irradiation in December 2006 and was completed in November 2009. The second experiment (AGR-2), which utilized the same experiment design as well as control and monitoring systems as AGR-1, started irradiation in June 2010 and is currently scheduled to be completed in April 2013. The design of this experiment and support systems will be briefly discussed, followed by the progress and status of the experiment to date.

  13. Food irradiation for phytosanitary and quarantine treatment

    Science.gov (United States)

    Irradiation at doses less than 1 kGy is an effective phytosanitary measure with minimal adverse effects on the quality of most fresh produce. There are internationally recognized guidelines for the use of irradiation as a phytosanitary measure and for the conduct of trade in irradiated fresh produce...

  14. SLIGHTLY IRRADIATED FUEL (SIF) INTERIM DISPOSITION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    NORTON SH

    2010-02-23

    CH2M HILL Plateau Remediation Company (CH2M HILL PRC) is proud to submit the Slightly Irradiated Fuel (SIF) Interim Disposition Project for consideration by the Project Management Institute as Project of the Year for 2010. The SIF Project was a set of six interrelated sub-projects that delivered unique stand-alone outcomes, which, when integrated, provided a comprehensive and compliant system for storing high risk special nuclear materials. The scope of the six sub-projects included the design, construction, testing, and turnover of the facilities and equipment, which would provide safe, secure, and compliant Special Nuclear Material (SNM) storage capabilities for the SIF material. The project encompassed a broad range of activities, including the following: Five buildings/structures removed, relocated, or built; Two buildings renovated; Structural barriers, fencing, and heavy gates installed; New roadways and parking lots built; Multiple detection and assessment systems installed; New and expanded communication systems developed; Multimedia recording devices added; and A new control room to monitor all materials and systems built. Project challenges were numerous and included the following: An aggressive 17-month schedule to support the high-profile Plutonium Finishing Plant (PFP) decommissioning; Company/contractor changeovers that affected each and every project team member; Project requirements that continually evolved during design and construction due to the performance- and outcome-based nature ofthe security objectives; and Restrictions imposed on all communications due to the sensitive nature of the projects In spite of the significant challenges, the project was delivered on schedule and $2 million under budget, which became a special source of pride that bonded the team. For years, the SIF had been stored at the central Hanford PFP. Because of the weapons-grade piutonium produced and stored there, the PFP had some of the tightest security on the Hanford

  15. High-dose secondary calibration laboratory accreditation program

    Energy Technology Data Exchange (ETDEWEB)

    Humphreys, J.C. [National Institute of Standards and Technology, Gaithersburg, MD (United States)

    1993-12-31

    There is a need for high-dose secondary calibration laboratories to serve the multi-billion dollar radiation processing industry. This need is driven by the desires of industry for less costly calibrations and faster calibration-cycle response time. Services needed include calibration irradiations of routine processing dosimeters and the supply of reference standard transfer dosimeters for irradiation in the production processing facility. In order to provide measurement quality assurance and to demonstrate consistency with national standards, the high-dose secondary laboratories would be accredited by means of an expansion of an existing National Voluntary Laboratory Accreditation Program. A laboratory performance criteria document is under development to implement the new program.

  16. Electron Beam Materials Irradiators

    Science.gov (United States)

    Cleland, Marshall R.

    2012-06-01

    Radiation processing is a well established method for enhancing the properties of materials and commercial products by treating them with ionizing energy in the form of high-energy electrons, X-rays, and gamma rays. Beneficial effects include polymerizing, cross-linking, grafting and degrading plastics, sterilizing single-use medical devices, disinfecting and disinfesting fresh foods, purifying drinking water, treating wastewater and other toxic waste materials that harm the environment, and many other applications that are still being evaluated. Industrial electron accelerators of several types have been developed and are being used for these applications. More than 1800 electron accelerators are presently installed in facilities worldwide for these purposes.

  17. Heavy ion irradiation induced dislocation loops in AREVA's M5® alloy

    Science.gov (United States)

    Hengstler-Eger, R. M.; Baldo, P.; Beck, L.; Dorner, J.; Ertl, K.; Hoffmann, P. B.; Hugenschmidt, C.; Kirk, M. A.; Petry, W.; Pikart, P.; Rempel, A.

    2012-04-01

    Pressurized water reactor (PWR) Zr-based alloy structural materials show creep and growth under neutron irradiation as a consequence of the irradiation induced microstructural changes in the alloy. A better scientific understanding of these microstructural processes can improve simulation programs for structural component deformation and simplify the development of advanced deformation resistant alloys. As in-pile irradiation leads to high material activation and requires long irradiation times, the objective of this work was to study whether ion irradiation is an applicable method to simulate typical PWR neutron damage in Zr-based alloys, with AREVA's M5® alloy as reference material. The irradiated specimens were studied by electron backscatter diffraction (EBSD), positron Doppler broadening spectroscopy (DBS) and in situ transmission electron microscopy (TEM) at different dose levels and temperatures. The irradiation induced microstructure consisted of - and -type dislocation loops with their characteristics corresponding to typical neutron damage in Zr-based alloys; it can thus be concluded that heavy ion irradiation under the chosen conditions is an excellent method to simulate PWR neutron damage.

  18. Comparison of irradiated and hydrogen implanted German RPV steels using PAS technique

    Energy Technology Data Exchange (ETDEWEB)

    Pecko, Stanislav, E-mail: stanislav.pecko@stuba.sk; Sojak, Stanislav; Slugeň, Vladimír

    2015-12-15

    Highlights: • German RPV steels were originally studied by positron annihilation spectroscopy. • Neutron irradiated and hydrogen ion implanted specimens were studied. • Both irradiation ways caused to increase of defect size. • We determined that the defect size was higher in implanted specimens. - Abstract: Radiation degradation of nuclear materials can be experimentally simulated via ion implantation. In our case, German reactor pressure vessel (RPV) steels were studied by positron annihilation lifetime spectroscopy (PALS). This spectroscopic method is a really effective tool for the evaluation of microstructural changes and for the analysis of degradation of reactor steels due to irradiation. German commercial reactor pressure vessel steels, originally from CARISMA program, were used in our study. The German experimental reactor VAK was selected as the proper irradiation facility in the 1980s. A specimen in as-received state and 2 different irradiated cuts from the same material were measured by PALS and size of defects with their intensity was indentified. Afterwards there was prepared an experiment with concern in simulation of neutron irradiation by hydrogen ion implantation on a linear accelerator with energy of 100 keV. Results are concerning on comparison between defects caused by neutron irradiation and hydrogen implantation. The size and intensity of defects reached a similar level as in the specimens irradiated in the nuclear reactor due to hydrogen ions implantation.

  19. Collaborative investigations of in-service irradiated material from the Japan Power Demonstration Reactor pressure vessel

    Energy Technology Data Exchange (ETDEWEB)

    Corwin, W.R.; Broadhead, B.L. [Oak Ridge National Lab., TN (United States); Suzuki, M.; Kohsaka, A. [Japan Atomic Energy Research Institute, Tokai (Japan)

    1997-02-01

    There is a need to validate the results of irradiation effects research by the examination of material taken directly from the wall of a pressure vessel that has been irradiated during normal service. Just such an evaluation is currently being conducted on material from the wall of the pressure vessel from the Japan Power Demonstration Reactor (JPDR). The research is being jointly performed at the Tokai Research Establishment of the Japan Atomic Energy Research Institute (JAERI) and by the Nuclear Regulatory Commission (NRC)-funded Heavy-Section Steel Irradiation Program at the Oak Ridge National Laboratory (ORNL).

  20. Irradiation of Electronic Components and Circuits at the Portuguese Research Reactor: Lessons Learned

    Science.gov (United States)

    Marques, J. G.; Ramos, A. R.; Fernandes, A. C.; Santos, J. P.

    2016-06-01

    A program was started in 1999 in the Portuguese Research Reactor to test electronics components and circuits for the LHC facility at CERN, initially with a dedicated in-pool irradiation container used at a reactor power of 2 kW and later an irradiation chamber outside the pool, with tailored neutron and gamma filters that could be used at 1 MW. Practice has shown the need to introduce several improvements to the irradiation procedures and infrastructures over the years. In this paper, we review the lessons learned and the major improvements introduced.

  1. Immunologic competence in adults following thymic irradiation in infancy

    Energy Technology Data Exchange (ETDEWEB)

    Ammann, A.J.; Wara, W.M.; Wara, D.W.; Phillips, T.L.

    1977-07-01

    Removal of, or irradiation to, the thymus during the neonatal period in man has resulted in no reported adverse effects on cellular immunity, although thymectomy in neonatal experimental animals is known to produce profound immunological disturbances. Adverse effects in humans may not be recognized until several decades have passed. The immunological capabilities of 7 adults with histories of thymic irradiation as infants were evaluated; normal tests results indicated intact immune systems in all cases. The 3 women tested, however, had abnormal clinical histories, including 2 with multiple tumors and 1 with chronic mucocutaneous candidiasis.

  2. Submicro foaming in biopolymers by UV pulsed laser irradiation

    Science.gov (United States)

    Oujja, Mohamed; Rebollar, Esther; Gaspard, Solenne; Abrusci, Concepción; Catalina, Fernando; Lazare, Sylvain; Castillejo, Marta

    2006-05-01

    Microstructuring of polymers and biopolymers is of application in medical technology and biotechnology. Using different fabrication techniques three-dimensionally shaped and micro structured constructs can be developed for drug release and tissue engineering. As an alternative method, laser microstructuring offers a series of advantages including high resolution capability, low heat deposition in the substrate and high level of flexibility. In this work we present evidence of laser microfoam formation in collagen and gelatine by nanosecond pulsed laser irradiation in the UV at 248 and 266 nm. Irradiation at 355 nm produces melting followed by resolidification of the substrate, whereas irradiation at 532 and 1064 nm induces the formation of craters of irregular contours. Single pulse irradiation of a collagen film with an homogenized KrF microbeam yields a 20 μm thick expanded layer, which displays the interesting features of a nanofibrous 3-dimensional network with open cells. In gelatine, irradiation at 248 and 266 nm produces similar morphological modifications. The effect of the structural properties of the substrate on the laser induced microfoam is studied by comparing gelatines differing in gel strength (Bloom values 225 and 75) and in crosslinking degree. While results are discussed on the basis of thermal and photomechanical mechanisms and of the role played by the water content of the substrates, it is thought that such structures could have a biomimic function in future 3D cell culture devices for research.

  3. Attentional ability among survivors of leukaemia treated without cranial irradiation.

    Science.gov (United States)

    Rodgers, J; Marckus, R; Kearns, P; Windebank, K

    2003-02-01

    Previous research has indicated that children who have received treatment for leukaemia which includes cranial irradiation exhibit deficits in their ability to focus attention. It has been suggested that the use of cranial irradiation may have a role to play in long term sequelae. To investigate neuropsychological functioning among children treated for leukaemia without cranial irradiation. In a cross sectional study, 17 leukaemic patients and their sibling controls were assessed using a neuropsychological model of attention. All were treated on the UKALL XI protocol and none had received cranial irradiation. Participants completed the Arithmetic subtest and Digit Span subtest of the Weschler Intelligence Scale for Children-Revised to assess focus-encode elements of attention; the Coding subtest and the Speed of Information subtest of the BAS to assess focus-execute aspects of attention; the VIGIL computerised battery to assess sustain elements of attention; and the Wisconsin Card Sorting test to assess the ability to shift attention. These children did not exhibit the deficits witnessed in previous cohorts, and were performing at comparable levels to their controls on all measures of attention These findings suggest that children who have received treatment for leukaemia without the use of cranial irradiation do not show the neuropsychological insult found in earlier treatment groups.

  4. Pulsed-Laser Irradiation Space Weathering Of A Carbonaceous Chondrite

    Science.gov (United States)

    Thompson, M. S.; Keller, L. P.; Christoffersen, R.; Loeffler, M. J.; Morris, R. V.; Graff, T. G.; Rahman, Z.

    2017-01-01

    Grains on the surfaces of airless bodies experience irradiation from solar energetic particles and melting, vaporization and recondensation processes associated with micrometeorite impacts. Collectively, these processes are known as space weathering and they affect the spectral properties, composition, and microstructure of material on the surfaces of airless bodies, e.g. Recent efforts have focused on space weathering of carbonaceous materials which will be critical for interpreting results from the OSIRIS-REx and Hayabusa2 missions targeting primitive, organic-rich asteroids. In addition to returned sample analyses, space weathering processes are quantified through laboratory experiments. For example, the short-duration thermal pulse from hypervelocity micrometeorite impacts have been simulated using pulsed-laser irradiation of target material e.g. Recent work however, has shown that pulsed-laser irradiation has variable effects on the spectral properties and microstructure of carbonaceous chondrite samples. Here we investigate the spectral characteristics of pulsed-laser irradiated CM2 carbonaceous chondrite, Murchison, including the vaporized component. We also report the chemical and structural characteristics of specific mineral phases within the meteorite as a result of pulsed-laser irradiation.

  5. Irradiation Processing Department monthly record report, July 1958

    Energy Technology Data Exchange (ETDEWEB)

    1958-08-21

    This document details activities of the irradiation processing department during the month of July, 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  6. Irradiation Processing Department monthly record report, June 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-07-19

    This document details activities of the irradiation processing department during the month of June 1957. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; production and reactor operations; facilities engineering operation; employee relations operation; and financial operation.

  7. Irradiation Processing Department, monthly record report, January 1958

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1958-02-21

    This document details activities of the irradiation processing department during the month of January, 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  8. Irradiation Processing Department monthly record report, May 1958

    Energy Technology Data Exchange (ETDEWEB)

    1958-06-20

    This document details activities of the irradiation processing department during the month of May 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  9. Irradiation Processing Department monthly record report, November 1958

    Energy Technology Data Exchange (ETDEWEB)

    1958-12-19

    This document details activities of the irradiation processing department during the month of November 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operation; production and reactor operations; facilities engineering operation; employee relations operations; and financial operation.

  10. Irradiation Processing Department monthly record report, March 1958

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1958-04-21

    This document details activities of the irradiation processing department during the month of March, 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  11. Irradiation Processing Department monthly record report, February 1958

    Energy Technology Data Exchange (ETDEWEB)

    1958-03-21

    This document details activities of the irradiation processing department during the month of February 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; production and reactor operations; facilities engineering operations; employee relations operation; and, financial operation.

  12. Irradiation Processing Department monthly record report, November 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-11-20

    This document details activities of the irradiation processing department during the month of November 1957. A general summary is included at the start of the report, after which the report is divided int the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  13. Irradiation Processing Department monthly record report, September 1956

    Energy Technology Data Exchange (ETDEWEB)

    1956-10-23

    This document details activities of the irradiation processing department during the month of September 1956. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; production and reactor operations; facilities engineering operation; employee relations operations; and financial operation.

  14. Irradiation Processing Department monthly record report, August 1957

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1957-09-20

    This document details activities of the Irradiation Processing Department during the month of August, 1957. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and engineering; operations; production and reactor operations; facilities engineering operation; employee relations operation; and financial operation.

  15. Irradiation Processing Department monthly record report, December 1959

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1960-01-22

    This document details activities of the irradiation processing department during the month of December, 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  16. Irradiation Processing Department monthly record report, August 1958

    Energy Technology Data Exchange (ETDEWEB)

    1958-09-19

    This document details activities of the irradiation processing department during the month of August, 1958. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  17. Irradiation Processing Department monthly record report, October 1959

    Energy Technology Data Exchange (ETDEWEB)

    1959-11-20

    This document details activities of the irradiation processing department during the month of October, 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor operations; Facilities Engineering operation; Employee Relations Operation; and Financial operation.

  18. Irradiation Processing Department monthly record report, April 1987

    Energy Technology Data Exchange (ETDEWEB)

    1957-05-21

    This document details activities of the irradiation processing department during the month of April 1957. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; production and reactor operations; facilities engineering operation; employee relations operation; and financial operation.

  19. Irradiation Processing Department, monthly record report, February, 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-03-22

    This document details activities of the irradiation processing department at the Hanford Reservation during the month of February, 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operation; Manufacturing Operation; Facilities Engineering Operation; Relations Practices Operation; Financial Operation; and NPR operation.

  20. Irradiation Processing Department monthly record report, July 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-08-20

    This document details activities of the irradiation processing department during the month of July, 1957. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations: Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  1. Irradiation Processing Department monthly record report, October 1956

    Energy Technology Data Exchange (ETDEWEB)

    1956-11-21

    This document details activities of the irradiation processing department during the month of October, 1956. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  2. Loop Growth and Point-Defect Profiles during HVEM Irradiation

    DEFF Research Database (Denmark)

    Leffers, Torben; Singh, Bachu Narain

    1979-01-01

    The point-defect profile in a thin foil is included in the model for the growth of dislocation loops during HVEM irradiation suggested by Kiritani, Yoshida, Takata, and Maehara, and the possible effect of divacancies is discussed. It is found that there is a fairly wide transition range between...

  3. Irradiation Processing Department monthly record report, March 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-04-19

    This document details activities of the irradiation processing department during the month of March, 1957. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  4. Irradiation Processing Department monthly record report, May 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-06-21

    This document details activities of the irradiation processing department during the month of May 1957. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; production and reactor operation; facilities engineering operation; employee relations operation; and financial operation.

  5. Irradiation Processing Department monthly record report, March 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-04-21

    This document details activities of the Irradiation Processing Department during the month of March, 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  6. Irradiation Processing Department monthly record report, January 1959

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1959-02-20

    This document details activities of the irradiation processing department during the month of January 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering operation; Employee Relations Operation; and Financial Operation.

  7. Irradiation Processing Department monthly record report, August 1959

    Energy Technology Data Exchange (ETDEWEB)

    1959-09-21

    This document details activities of the irradiation processing department during the month of August 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; production and reactor operations; facilities engineering operation; employee relations operation; and financial operation.

  8. Irradiation Processing Department monthly record report, September 1959

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1959-10-22

    This document details activities of the irradiation processing department during the month of September, 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  9. Irradiation Processing Department monthly record report, July 1959

    Energy Technology Data Exchange (ETDEWEB)

    1959-08-21

    This document details activities of the irradiation processing department during the month of July 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; facilities engineering operation; employee relations operation; and financial operation.

  10. Irradiation Processing Department monthly record report, March 1959

    Energy Technology Data Exchange (ETDEWEB)

    Greninger, A.B.

    1959-04-21

    This document details activities of the irradiation processing department during the month of March, 1959. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  11. Irradiation Processing Department monthly record report, January 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-02-19

    This document details activities of the irradiation processing department during the month of January 1960. A general summary is included at the start of the report, after which the report is divided into the following sections: Research and Engineering Operations; Production and Reactor Operations; Facilities Engineering Operation; Employee Relations Operation; and Financial Operation.

  12. Irradiation Processing Department monthly record report, November 1956

    Energy Technology Data Exchange (ETDEWEB)

    1956-12-20

    This document details activities of the irradiation processing department during the month of November 1956. A general summary is included at the start of the report, after which the report is divided into the following sections: research and engineering operations; production and reactor operations; facilities engineering operation; employee relations operation; and financial operation.

  13. Development of a Low Temperature Irradiation Capsule for Research Reactor Materials

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Kee Nam; Cho, Man Soon; Lee, Cheol Yong; Yang, Sung Woo; Shin, Yoon Taek; Park, Seng Jae; Kang, Suk Hoon; Kang, Young Hwan; Park, Sang Jun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-07-01

    A new capsule design was prepared and tested at HANARO for a neutron irradiation of core materials of research reactors as a part of the research reactor development project. Irradiation testing of the materials including graphite, beryllium, and zircaloy-4 that are supposed to be used as core materials in research reactors was required for irradiation at up to 8 reactor operation cycles at low temperature (<100 .deg. C). Therefore, three instrumented capsules were designed and fabricated for an evaluation of the neutron irradiation properties of the core materials (Graphite, Be, Zircaloy-4) of research reactors. The capsules were first designed and fabricated to irradiate materials at low temperature (<100 .deg. C) for a long cycle of 8 irradiation cycles at HANARO. Therefore, the safety of the new designed capsule should be fully checked before irradiation testing. Out-pile performance and endurance testing before HANARO irradiation testing was performed using a capsule under a 110% condition of a reactor coolant flow amount. The structural integrity of the capsule was analyzed in terms of a vibration-induced fatigue cracking of a rod tip of the capsule that is suspected to be the most vulnerable part of a capsule. Another two capsules were irradiated at HANARO for 4 cycles, and one capsule was transferred to a hot cell to examine the integrity of the rod tip of the capsule. After confirming the soundness of the 4 cycle-irradiated capsule, the remaining capsule was irradiated at up to 8 cycles at HANARO. Based on the structural integrity analysis of the capsule, an improved capsule design will be suggested for a longer irradiation test at HANARO.

  14. Low-intensity laser irradiation at 660 nm stimulates cytochrome c oxidase in stressed fibroblast cells.

    Science.gov (United States)

    Houreld, Nicolette N; Masha, Roland T; Abrahamse, Heidi

    2012-07-01

    Low-intensity laser irradiation (LILI) has been used to modulate a variety of biological processes, including diabetic wound healing. The mechanism of action is thought to exist primarily with the mitochondria. This study aimed to determine the effect of irradiation on normal, diabetic, and ischemic mitochondrial electron transport chain (ETC) complexes. Normal, diabetic and ischemic human skin fibroblast mitochondria were irradiated in vitro at a wavelength of 660 nm and a fluence of either 5 or 15 J/cm(2). Non-irradiated mitochondria served as controls. Enzyme activities of mitochondrial complexes I, II, III, and IV were determined immediately post-irradiation. Normal, diabetic, and ischemic cells were irradiated and adenosine triphosphate (ATP) and active mitochondria were determined by luminescence and fluorescent microscopy, respectively. Irradiated diabetic mitochondria at a fluence of 15 J/cm(2) showed a significant decrease in complex III activity (P < 0.05). Normal (P < 0.01) and diabetic (P < 0.05) mitochondria irradiated at either 5 or 15 J/cm(2) showed a significant increase in complex IV activity. ATP results showed a significant increase in irradiated normal cells (5 J/cm(2); P < 0.05) and diabetic cells (15 J/cm(2); P < 0.01). There was a higher accumulation of active mitochondria in irradiated cells than non-irradiated cells. Irradiation at 660 nm has the ability to influence mitochondrial enzyme activity, in particular cytochrome c oxidase. This leads to increased mitochondrial activity and ATP synthesis. Copyright © 2012 Wiley Periodicals, Inc.

  15. Irradiated bivalve mollusks: Use of EPR spectroscopy for identification and dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Alberti, Angelo, E-mail: aalberti@isof.cnr.it [CNR-ISOF, Area della Ricerca di Bologna, Via P. Gobetti 101, Bologna I-40129 (Italy); Chiaravalle, Eugenio [Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia 20, Foggia I-71100 (Italy); Fuochi, Piergiorgio; Macciantelli, Dante [CNR-ISOF, Area della Ricerca di Bologna, Via P. Gobetti 101, Bologna I-40129 (Italy); Mangiacotti, Michele, E-mail: michelemangiacotti@libero.it [Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia 20, Foggia I-71100 (Italy); Marchesani, Giuliana [Istituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia 20, Foggia I-71100 (Italy); Plescia, Elena [CNR-ISOF, Area della Ricerca di Bologna, Via P. Gobetti 101, Bologna I-40129 (Italy)

    2011-12-15

    High energy radiation treatment of foodstuff for microbial control and shelf-life extension is being used in many countries. However, for consumer protection and information, the European Union has adopted the Directives 1999/2/EC and 1999/3/EC to harmonize the rules concerning the treatment and trade of irradiated foods in EU countries. Among the validated methods to detect irradiated foods the EU directives also include Electron Paramagnetic Resonance (EPR/ESR) spectroscopy. We describe herein the use of EPR for identification of four species of bivalve mollusks, i.e. brown Venus shells (Callista chione), clams (Tapes semidecussatus), mussels (Mytilus galloprovincialis) and oysters (Ostrea edulis) irradiated with {sup 60}Co {gamma}-rays. EPR could definitely identify irradiated seashells due to the presence of long-lived free radicals, primarily CO{sub 2}{sup -}, CO{sub 3}{sup 3-}, SO{sub 2}{sup -} and SO{sub 3}{sup -} radical anions. The presence of other organic free radicals, believed to originate from conchiolin, a scleroprotein present in the shells, was also ascertained. The use of one of these radicals as a marker for irradiation of brown Venus shells and clams can be envisaged. We also propose a dosimetric protocol for the reconstruction of the administered dose in irradiated oysters. - Highlights: > EPR spectroscopy is confirmed a valuable identification tool for irradiated mollusks. > A conchiolin-derived radical can be used as irradiation marker for some mollusks. > A reliable protocol is outlined for dose reconstruction of irradiated oysters.

  16. Elimination of coliforms and Salmonella spp. in sheep meat by gamma irradiation treatment.

    Science.gov (United States)

    Henriques, Luciana Salles Vasconcelos; da Costa Henry, Fábio; Barbosa, João Batista; Ladeira, Silvania Alves; de Faria Pereira, Silvia Menezes; da Silva Antonio, Isabela Maria; Teixeira, Gina Nunes; Martins, Meire Lelis Leal; de Carvalho Vital, Helio; dos Prazeres Rodrigues, Dália; dos Reis, Eliane Moura Falavina

    2013-12-01

    This study aimed at evaluating the bacteriological effects of the treatment of sheep meat contaminated with total coliforms, coliforms at 45 °C and Salmonella spp. by using irradiation at doses of 3 kGy and 5 kGy. Thirty sheep meat samples were collected from animals located in Rio de Janeiro State, Brazil, and then grouped in three lots including 10 samples: non-irradiated (control); irradiated with 3 kGy; and irradiated with 5 kGy. Exposure to gamma radiation in a (137)Cs source-driven irradiating facility was performed at the Nuclear Defense Section of the Brazilian Army Technological Center (CTEx) in Rio de Janeiro. The samples were kept under freezing temperature (-18 °C) until the analyses, which occurred in two and four months after irradiation. The results were interpreted by comparison with the standards of the current legislation and demonstrated that non-irradiated samples were outside the parameters established by law for all groups of bacteria studied. Gamma irradiation was effective in inactivating those microorganisms at both doses tested and the optimal dose was achieved at 3 kGy. The results have shown not only the need for sanitary conditions improvements in slaughter and processing of sheep meat but also the irradiation effectiveness to eliminate coliform bacteria and Salmonella spp.

  17. Probabilistic Forecasts of Solar Irradiance by Stochastic Differential Equations

    DEFF Research Database (Denmark)

    Iversen, Jan Emil Banning; Morales González, Juan Miguel; Møller, Jan Kloppenborg

    2014-01-01

    Probabilistic forecasts of renewable energy production provide users with valuable information about the uncertainty associated with the expected generation. Current state-of-the-art forecasts for solar irradiance have focused on producing reliable point forecasts. The additional information...... included in probabilistic forecasts may be paramount for decision makers to efficiently make use of this uncertain and variable generation. In this paper, a stochastic differential equation framework for modeling the uncertainty associated with the solar irradiance point forecast is proposed. This modeling...... approach allows for characterizing both the interdependence structure of prediction errors of short-term solar irradiance and their predictive distribution. Three different stochastic differential equation models are first fitted to a training data set and subsequently evaluated on a one-year test set...

  18. Sleep apnea syndrome after irradiation of the neck

    Energy Technology Data Exchange (ETDEWEB)

    Herlihy, J.P.; Whitlock, W.L.; Dietrich, R.A.; Shaw, T. (Pulmonary Disease Service, Presidio of San Francisco, CA (USA))

    1989-12-01

    After irradiation of the neck for a squamous cell carcinoma of the tonsillar pillar and vocal cord, a 71-year-old man presented with a rapidly progressive sleep apnea syndrome. Previous reports describe the condition of patients with obstructive sleep apnea that developed after neck irradiation and secondary to supraglottic edema. Our patient had an obstructive component to his apnea similar to that described in previous cases, but, in addition, he had hypothyroidism. Myxedema is a well-described cause of both obstructive and central apnea. We believe both contributed to his condition. He was successfully treated by placement of a tracheostomy and by thyroid supplementation. In patients who present with sleep apnea after neck irradiation, especially with acute or severe symptoms, the differential diagnosis should include both a central cause from hypothyroidism as well as a peripheral obstructive cause from laryngeal edema.

  19. Irradiation-induced hardening and softening of CLAM steel under Fe ion irradiation

    Science.gov (United States)

    Li, Qingshan; Shen, Yinzhong; Huang, Xi; Xu, Zhiqiang; Zhu, Jun

    2017-11-01

    The irradiation-induced hardening and softening of CLAM steel irradiated with 3.5 MeV Fe13+ ions at temperatures of 300 °C and 550 °C were investigated by nanoindentation tests in combination with microstructures. Irradiation- induced hardening occurred in the steel irradiated at 300 °C to doses of 0.46 dpa, 0.94 dpa, and 2.79 dpa. The hardening occurred at 300 °C is mainly attributed to the formation of irradiation-produced dislocation loops and a network of tangled dislocations in the irradiated steel samples. Significant hardening was found in the steel irradiated at 550 °C to 0.38 dpa. On the contrary, irradiation-induced softening occurred in the steel irradiated at 550 °C to both 0.76 dpa and 2.75 dpa. Irradiation-produced dislocation loops are not dominant effect on the irradiation hardening of the steel samples irradiated at 550 °C. The hardening and softening of the irradiated steel were explained in terms of the irradiation-produced defects and recovery process occurred during the irradiation.

  20. ThO2-based pellet fuels - their properties, methods of fabrication, and irradiation performance: a critical assessment of the state of the technology and recommendations for further work

    Energy Technology Data Exchange (ETDEWEB)

    Hart, P.E.; Griffin, C.W.; Hsieh, K.A.; Matthews, R.B.; White, G.D.

    1979-09-01

    This critical assessment of the ThO/sub 2/-UO/sub 2/ pellet fuel technology was conducted in support of the Fuels Refabrication and Development Program (FRAD). Included in this critical review are the following areas: powder preparation; pellet fabrication; fuel chemical, physical, and mechanical properties; and fuel irradiation performance. The authors identify (1) areas where data are either deficient or lacking and (2) requirements for additional development and experimental work.

  1. Hourly distributions of the diffuse fraction of global solar irradiation in Cordoba (Spain)

    Energy Technology Data Exchange (ETDEWEB)

    Posadillo, R.; Lopez Luque, R. [Grupo de Investigacion de Fisica para las Energias y Recursos Renovables, Dpto. de Fisica Aplicada/UCO, Edificio C2 Campus de Rabanales, 14071 Cordoba (Spain)

    2009-02-15

    Hourly global irradiations on tilted planes are required for dimensioning PV systems. However, for most sites, only global irradiations on a horizontal plane are available, and, given that to calculate the global irradiation on inclined planes the first step is to determine the diffuse component and this is not collected, we have studied the behaviour of the diffuse component on an hourly basis. Most parametrization models for the derivation of hourly diffuse irradiance from hourly global irradiance involve the clearness index, a parameter that implicitly includes solar altitude. The present paper has focused on the possibility of also including ''mean solar altitude anti {alpha}'' explicitly as a parameter in addition to the clearness index. Several analytical models are proposed, validated and compared here, using solar data collected on our station located in Cordoba (Spain). (author)

  2. Irradiation and postangioplasty restenosis

    Energy Technology Data Exchange (ETDEWEB)

    Ishiwata, Sugao; Robinson, K.; Chronos, N. [Toranomon Hospital, Tokyo (Japan); Crocker, I.R.; King, S.B.III

    2000-09-01

    One of the most intriguing developments in recent years towards prevention of restenosis after angioplasty is the use of ionizing radiation. The background for the use of radiation treatment for this application is sound, since radiation is used not only to treat malignant cancerous growths but also is used for treatment of benign hyperplastic disorders such as post-surgical keloid formation and recurrence of pterygium after surgical removal. Restenosis can be considered a form of overexuberant wound healing triggered by angioplasty. Ionizing radiation inhibits serum-stimulated proliferation of many cell types including fibroblasts and smooth muscle cells in vitro and also suppresses the synthesis of collagen by cultured fibroblasts. Liermann who showed inhibition of post-stent restenosis first used ionizing radiation for restenosis prevention clinically in iliac and iliofemoral arteries. Subsequently, extensive animal studies in various restenosis models have shown a profound inhibitory effect of catheter-based radiation (endovascular brachytherapy) on neointima formation and overall vessel shrinkage (negative remodeling). Based on these results clinical trials have been initiated with several types of devices and isotopes. Among these are {sup 192}Ir, {sup 32}P, {sup 90}Y, {sup 90}Sr/Y and {sup 188}Re. Additionally, radioactive stents have been developed; devices for clinical use are made radioactive at the {mu}Ci level by surface implantation of 32P ions. Results from early clinical trials are encouraging and brachytherapy appears safe for clinical use and at an appropriate dose, may be highly effective for restenosis prevention. (author)

  3. Development of system for product tracking and data acquisition of data irradiation process in large gamma irradiators

    Energy Technology Data Exchange (ETDEWEB)

    Soares, Jose R., E-mail: joseroberto.soares@mackenzie.br [Universidade Presbiteriana Mackenzie. Escola de Engenharia. Sao Paulo, SP (Brazil); Rela, Paulo R.; Costa, Fabio E., E-mail: prela@ipen.br, E-mail: fecosta@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The sterilization of medical care products using ionizing radiation is a consolidated technique. In Brazil there are in operation gamma irradiators with capacity between 0.37 PBq (10kCi) 185 PBq (5 MCi) using radioisotopes {sup 60}Co as radiation source. The developed work provides an accurate control and data acquisition for the application of good manufacturing practices during all phases of an irradiation process, required by the standards of ANVISA, technical ISO and IAEA recommendations for the treatment of foods and medical products. All the steps involved in the irradiation treatment are mapped into process flow (work flow), where each agent (participant) has its systematized tasks. The automatic data process acquisition using wireless ZigBee technology, monitoring and control, are based on a set of tools (free software licenses) integrated by a network of efficient communication, including the use of Web resources. Using the Gamma Irradiator Multipurpose IPEN/CNEN-SP all the development was performed to be applied in irradiators' facilities operating in industrial scale. The system enables a complete traceability of the process, in real time, for any participant and also the storage of the corresponding records to be audited. (author)

  4. Analysis of the severe complications of irradiation of carcinoma of the uterine cervix: treatment with intracavitary radium and parametrial irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Unal, A.; Hamberger, A.D.; Seski, J.C.

    1981-08-01

    Between January 1967 and December 1974, 254 patients with carcinoma of the uterine cervix were treated with either intracavitary radium and parametrial irradiation or 2000 rad whole pelvis irradiation followed by intracavitary radium and parametrial irradiation. In general, these patients had tumors of relatively limited volume and vaginal and uterine anatomy that was favorable for intracavitary radium. Not all patients had a lymphangiogram performed prior to irradiation. Of those who did, only patients with negative lymphangiograms are included in this analysis. All patient had a minimum follow-up of four years. The absolute four year survival rate for this group of patients was 86%. Only 6.3% of patients died of disease. The incidence of severe complications was 7.5%. Complications were associated with a high number of milligram hours of radium plus a high dose of external irradiation, in combination with either asymmetry of the radium system and/or history of previous pelvic inflammatory disease, pelvic surgery, or diverticulosis.

  5. Food irradiation development in Pakistan

    Science.gov (United States)

    Khan, I.

    The large scale trials were held to extend the storage life of potatoes, onions and dry fruits by gamma radiation. It was concluded that radiation preservation of potatoes and onions was much cheaper as compared to conventional methods. A dose of 1 kGy can control the insects in dry fruits and nuts. The consumers' acceptability and market testing performed during the last four years are also conducive to the commercialization of the technology in this country. The Government of Pakistan has accorded clearance for the irradiation of some food items like potatoes, onions, garlic and spices for human consumption. The Pakistan Radiation Services (PARAS), the commercial irradiator (200 Kci) at Lahore, has already started functioning in April, 1987. It is planned to start large scale sterilization of spices by gamma radiation in PARAS shortly.

  6. Spectrophotometric analysis of irradiated spices

    Energy Technology Data Exchange (ETDEWEB)

    Josimovic, L.; Cudina, I.

    1987-01-01

    Seven different spices (thyme, cinnamon, coriander, caraway, pimento, paprika, black pepper) were treated by gamma radiation at an absorbed dose of 10 kGy, and the effect on chemical quality was determined. The effects of this dose were assessed by spectrophotometric analysis of some water-soluble constituents of spices (carbohydrates; carbonyl compounds) and on the content of water-insoluble steam-volatile oils. The colour of paprika and the content of piperine in pepper held in different packaging materials were measured in unirradiated and irradiated samples as a function of storage time. In all cases irradiation does not bring about any distinct qualitative or quantitative chemical changes based on spectrophotometric analysis of spice extracts.

  7. Study of rice. gamma. -irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Lien, J.J.; Chau, R.S.; Chen, S.C.; Chu, S.L.; Fu, Y.K.; Fang, C.K.; Fu, Y.H.

    1981-03-01

    The purpose of this experiment was to investigate whether the /sup 60/Co gamma-irradiated milled rice packed in economic and practical sealed bags could be preserved in common granaries in Taiwan for more than one year rather than slightly over one month without quality deterioration. As a result of this experiment we found that during the preservation of over a period of 18 months, the contents, such as moisture, ash, protein and fiber, of Tainan-5 Bon-Lai (Japonica Type) rice irradiated with 20 and 40 krad doses were quite stable, whereas reducing sugar showed slight fluctuations but did not vary significantly either. The fat, vitamin B/sub 1/ and niacin contents were found being reduced, while the increase in fatty acid content was an inevitable phenomenon along with the proceeding of the preservation.

  8. Histopathologic study on irradiated human developing teeth

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Yasunori (Iwate Medical Coll., Morioka (Japan). School of Dentistry)

    1982-12-01

    The patient was a 7-year-old boy who had been suffering from Ewing's sarcoma originating in the mandible. Irradiation with 8000 rad of Linac was performed on the mandible prior to mandibulectomy. The results of the histopathologic examination of the teeth including resected material were as follows: 1. Although the tumor tissue was not found in the resected material, complete resoption of the medullar trabecular bone with fibrosis was noted in the area between the first molar region and the mandibular ramus. 2. The first and the second premolar teeth were in the early stage of root formation, and conglomerates of dysplastic dentin were formed in the proliferative zones. This dysplastic dentin was surrounded by loose fibrous connective tissues. 3. The dysplastic dentin showed low mineralization, embedded irregular arranged-fibrous tissue matrix and scattered various-sized lacunae containing a few tiny and pyknotic cells. 4. Irregularly arranged odontoblasts with a pyknotic appearance were found along the tubular dentin, but diffuse fibrosis occurred in the pulpal tissues. 5. The first molar tooth had completed its root formation. Various amounts of osteodentin were formed at the secondary dentin layer. Inner-resorption of dentin and fibrosis of the pulpal tissue were also found. These changes concerning the first molar tooth were also due to the effects of irradiation. 6. The second molar tooth was resorbed by tumor infiltration, and dysplastic dentin was on the resorbed surface of the dentin.

  9. Neutron irradiation induced amorphization of silicon carbide

    Science.gov (United States)

    Snead, L. L.; Hay, J. C.

    1999-07-01

    This paper provides the properties of bulk stoichiometric silicon carbide which has been amorphized under neutron irradiation. Both high purity single crystal hcp and high purity, highly faulted (cubic) chemically vapor deposited (CVD) SiC were irradiated at approximately 60°C to a total fast neutron fluence of 2.6 × 10 25 n/m 2. Amorphization was seen in both materials as evidenced by TEM, electron diffraction and X-ray diffraction techniques. Physical properties for the amorphized single crystal material are reported including large changes in density (-10.8%), elastic modulus as measured using a nanoindentation technique (-45%), hardness as measured by nanoindentation (-45%), and standard Vickers hardness (-24%). Similar property changes are observed for the amorphized CVD SiC. Using measured thermal conductivity data for the CVD SiC sample, the critical temperature for amorphization at this neutron dose and flux, above which amorphization is not possible, is estimated to be greater than ˜125°C.

  10. Pterygia: Single-fraction postoperative beta irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Beyer, D.C. (Radiation Oncologists of Central Arizona, Phoenix (USA))

    1991-02-01

    A retrospective evaluation was performed with records of 128 patients with 146 eyes that underwent applications of strontium-90 after pterygium excisions performed between 1982 and 1988. With a median follow-up of 13 months, 135 eyes were evaluable. Most pterygia (127 of 135) were treated with a single postoperative application of Sr-90 that delivered 3,000 cGy of beta radiation in one fraction. The actuarial freedom from relapse was 87%; all recurrences occurred within the first 18 months, and 46% of these within the first 3 months. Of the 13 recurrences, 10 have been re-treated with surgery and a second course of beta irradiation with excellent results. All eight eyes for which follow-up was available had no evidence of disease. The ultimate control rate was 96.3% for the series. Correlation of various treatment parameters, including age, bilaterality, prior recurrence, and interval from surgery to irradiation, was performed, and no statistically significant difference was seen. No serious complications have developed. Transient conjunctivitis and photophobia were almost universally seen, with five cases lasting beyond 5 months. The authors conclude that a single application of Sr-90 after surgery is effective and safe in managing pterygia.

  11. Comparison between the Strength Levels of Baseline Nuclear-Grade Graphite and Graphite Irradiated in AGC-2

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, Mark Christopher [Idaho National Laboratory (INL), Idaho Falls, ID (United States)

    2015-07-01

    This report details the initial comparison of mechanical strength properties between the cylindrical nuclear-grade graphite specimens irradiated in the second Advanced Graphite Creep (AGC-2) experiment with the established baseline, or unirradiated, mechanical properties compiled in the Baseline Graphite Characterization program. The overall comparative analysis will describe the development of an appropriate test protocol for irradiated specimens, the execution of the mechanical tests on the AGC-2 sample population, and will further discuss the data in terms of developing an accurate irradiated property distribution in the limited amount of irradiated data by leveraging the considerably larger property datasets being captured in the Baseline Graphite Characterization program. Integrating information on the inherent variability in nuclear-grade graphite with more complete datasets is one of the goals of the VHTR Graphite Materials program. Between “sister” specimens, or specimens with the same geometry machined from the same sub-block of graphite from which the irradiated AGC specimens were extracted, and the Baseline datasets, a comprehensive body of data will exist that can provide both a direct and indirect indication of the full irradiated property distributions that can be expected of irradiated nuclear-grade graphite while in service in a VHTR system. While the most critical data will remain the actual irradiated property measurements, expansion of this data into accurate distributions based on the inherent variability in graphite properties will be a crucial step in qualifying graphite for nuclear use as a structural material in a VHTR environment.

  12. Microstructural processes in irradiated materials

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Thak Sang; Morgan, Dane; Jiao, Zhijie; Almer, Jonathan; Brown, Donald

    2016-04-01

    This is an editorial article (preface) for the publication of symposium papers in the Journal of Nuclear materials: These proceedings contain the papers presented at two symposia, the Microstructural Processes in Irradiated Materials (MPIM) and Characterization of Nuclear Reactor Materials and Components with Neutron and Synchrotron Radiation, held in the TMS 2015, 144th Annual Meeting & Exhibition at Walt Disney World, Orlando, Florida, USA on March 15–19, 2015.

  13. Spectroscopic analysis of irradiated erythrocytes

    Energy Technology Data Exchange (ETDEWEB)

    Selim, Nabila S. [Biophysics Lab, Radiation Physics Department, National Center for Radiation Research and Technology (NCRRT), AEA, P.O. Box 29, Madinat Nasr, Cairo (Egypt); Desouky, Omar S., E-mail: omardesouky@yahoo.com [Biophysics Lab, Radiation Physics Department, National Center for Radiation Research and Technology (NCRRT), AEA, P.O. Box 29, Madinat Nasr, Cairo (Egypt); Ismail, Nagla M.; Dakrory, Amira Z. [Physics Department, Faculty of Girls for Arts, Sciences and Education, Ain Shams University, Cairo (Egypt)

    2011-12-15

    The aim of the present work is to study the effect of gamma radiation on the lipid part of the erythrocyte membrane, and to test the efficiency of lipoic acid as a radioprotector. This effect was evaluated using electron paramagnetic resonance (EPR), and Fourier transform infrared (FT-IR) spectroscopy. The results showed an increase in the number of spin density by 14%, 22% and 65% after exposure to 25, 50 and 100 Gy respectively; whereas there was a decline in the obtained density after incubation with lipoic acid by a factor of approximately 32%. The FT-IR spectra of the irradiated erythrocytes samples showed a marked decrease in the intensity of all characteristic peaks, which increased as the irradiation dose increased. The second-derivative of these spectra, allow the conformationally sensitive membrane acyl chain methylene stretching modes to be separated from the protein (mostly hemoglobin) vibrations that dominate the spectra of intact cells. The 2850 cm{sup -1} band showed changes in the band shape and position after exposure to 50 and 100 Gy. Therefore it can be concluded that the band at 2850 cm{sup -1} only is useful in monitoring the radiation effect of the lipids cell membrane intact cells. - Highlights: > Effect of {gamma} radiation on erythrocyte membrane was studied using EPR and FT-IR. > Efficiency of {alpha}-lipoic acid as radioprotector was tested. > Lipoic acid diminished the free radicals number after gamma irradiation by 32%. > FT-IR spectra of the irradiated erythrocyte showed a decrease in their intensity. > Lipoic acid enhances the membrane to resist the action of gamma radiation.

  14. Development of an irradiation system for a small size continuous run multipurpose gamma irradiator; Desenvolvimento do sistema de irradiacao em um irradiador multiproposito de cobalto-60 tipo compacto

    Energy Technology Data Exchange (ETDEWEB)

    Calvo, Wilson Aparecido Parejo

    2005-07-01

    The Radiation Technology Center from Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN/SP), Brazil, developed with a revolutionary design and national technology, a small size continuous run and multipurpose industrial gamma irradiator, to be used as a demonstration facility for manufacturers and contract service companies, which need economical and logistical in-house irradiation system alternatives. Also, to be useful for supporting the local scientific community on development of products and process using gamma radiation, assisting the traditional and potential users on process validation, training and qualification of operators and radioprotection officers. The developed technology for this facility consists of continuous tote box transport system, comprising a single concrete vault, where the automated transport system of products inside and outside of the irradiator utilizes a rotate door, integrated with the shielding, avoiding the traditional maze configuration. Covering 76 m{sup 2} of floor area, the irradiator design is product overlap sources and the maximum capacity of cobalt-60 wet sources is 37 P Bq (1 MCi). The performed quantification program of this multipurpose irradiator was based on AAMI/ISO 11137 standard, which recommends the inclusion of the following elements: installation and process quantification. The initial load of the multipurpose irradiator was 3.4 P Bq (92.1 k Ci) with 13 cobalt-60 sources model C-188, supplied by MDS Nordion Ion Technologies - Canada. For irradiator dose optimization, the source distribution was done using the software Cadgamma developed by IPEN-CNEN/SP. The poly-methylmethacrylate (PMMA) dosimeters system, certified by the International Dose Assurance Service (IDAS) of the International Atomic Energy Agency (IAEA) was used for irradiator dose mapping. The economic analysis, performance concerning to dose uniformity and cobalt-60 utilization efficiency were calculated and compared with other commercial

  15. Shear Punch Testing of BOR-60 Irradiated TEM Specimens

    Energy Technology Data Exchange (ETDEWEB)

    Saleh, Tarik A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Quintana, Matthew Estevan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Romero, Tobias J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-06-13

    As a part of the project “High Fidelity Ion Beam Simulation of High Dose Neutron Irradiation” an Integrated Research Program (IRP) project from the U.S. Department of Energy, Nuclear Energy University Programs (NEUP), TEM geometry samples of ferritic cladding alloys, Ni based super alloys and model alloys were irradiated in the BOR-60 reactor to ~16 dpa at ~370°C and ~400°C. Samples were sent to Los Alamos National Laboratory and subjected to shear punch testing. This report presents the results from this testing.

  16. Cooperative IASCC Research (CIR) Program

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, J.L. [Electric Power Research Inst., Palo Alto, CA (United States). Nuclear Power Group

    1998-03-01

    Irradiation assisted stress corrosion cracking (IASCC) describes intergranular environmental cracking of material exposed to ionizing radiation. The implications of IASCC are significant, both in terms of repair and outage costs as well as the potential for cracking in components that may be extremely difficult to repair or replace. Significant advancements have been made in the understanding of IASCC. However, it is clear that major unknowns persist and must be understood and quantified before the life of a reactor component at risk from IASCC can be predicted or significantly extended. Although individual organizations are continuing to effectively address IASCC, it became apparent that a more direct form of cooperation would be more timely and efficient in addressing the technical issues. Thus in 1995 EPRI formed the Cooperative IASCC Research (CIR) Program. This is a cooperative, jointly funded effort with participants from eight countries providing financial support and technical oversight. The efforts of the CIR Program are directed at the highest priority questions in the areas of material susceptibility, water chemistry and material stress. Major research areas of the Program are: (1) evaluation of IASCC mechanisms, (2) development of methodology for predicting IASCC, and (3) quantification of irradiation effects on metallurgy, mechanics and electrochemistry. Studies to evaluate various IASCC mechanisms include work to better understand the possible roles of radiation-induced segregation (RIS), radiation microstructure, bulk and localized deformation effects, overall effects on strength and ductility, hydrogen and helium effects, and others. Experiments are being conducted to isolate individual effects and determine the relative importance of each in the overall IASCC mechanism. Screening tests will be followed by detailed testing to identify the contribution of each effect over a range of conditions. The paper describes the completed and ongoing work being

  17. Irradiation effects on Zr-2.5Nb in power reactors

    Energy Technology Data Exchange (ETDEWEB)

    Song, C., E-mail: Carol.Song@cnl.ca [Canadian Nuclear Laboratories, Chalk River, Ontario (Canada)

    2016-06-15

    Zirconium alloys are widely used as structural materials in nuclear applications because of their attractive properties such as a low absorption cross-section for thermal neutrons, excellent corrosion resistance in water, and good mechanical properties at reactor operating temperatures. Zr-2.5Nb is one of the most commonly used zirconium alloys and has been used for pressure tube materials in CANDU (Canada Deuterium Uranium) and RBMK (Reaktor Bolshoy Moshchnosti Kanalnyy, 'High Power Channel-type Reactor') reactors for over 40 years. In a recent report from the Electric Power Research Institute, Zr-2.5Nb was identified as one of the candidate materials for use in normal structural applications in light-water reactors owing to its increased resistance to irradiation-induced degradation as compared with currently used materials. Historically, the largest program of in-reactor tests on zirconium alloys was performed by Atomic Energy of Canada Limited. Over many years of in-reactor testing and CANDU operating experience with Zr- 2.5Nb, extensive research has been conducted on the irradiation effects on its microstructures, mechanical properties, deformation behaviours, fracture toughness, delayed hydride cracking, and corrosion. Most of the results on Zr-2.5Nb obtained from CANDU experience could be used to predict the material performance under light water reactors. This paper reviews the irradiation effects on Zr-2.5Nb in power reactors (including heavy-water and light-water reactors) and summarizes the current state of knowledge. (author)

  18. Partial volume rat lung irradiation: an evaluation of early DNA damage.

    Science.gov (United States)

    Khan, M A; Hill, R P; Van Dyk, J

    1998-01-15

    to the spontaneous frequency. Lung cells obtained from the lung base or the lung apex of healthy controls and irradiated separately in vitro showed no regional differences in the induction of micronuclei. Cells from the lungs of rats injected with superoxide dismutase, within 1 h prior to irradiation of the lung base, and processed 16-18 h after irradiation showed a reduction in the number of MN in the shielded lung apex, indicating the possible involvement of oxygen radicals. These data indicate that cells in the lung base sustain more DNA damage than those in the lung apex when either region is irradiated; however, when the whole lung, is irradiated, the lung damage observed is similar in the two regions. Also, out-of-field effects are observed for the lung apex but not the lung base. Possible mechanisms include a clastogenic (chromosome damaging) factor produced in the plasma following irradiation and/or the production of oxygen radicals by activated lymphocytes/monocytes. The partial blocking of the DNA damage, observed in the unirradiated lung apex following irradiation of the lung base, by superoxide dismutase, suggests that oxygen radicals are involved in this out-of-field effect. These radicals are likely produced as a result of the induction of inflammatory cytokines, such as tumor necrosis factor (TNF) and interleukin-1 (IL-1) by the irradiation. The reason for the lack of an out-of-field effect in the lung base when the lung apex is irradiated is unknown, but may be due to the greater volume of lung irradiated in the lower lung field, because this is likely to affect the level of cytokines produced. Alternatively, it may reflect cytokines produced as a result of the partial liver irradiation that occurs with the lower lung field.

  19. Microstructural observations of HFIR-irratiated austenitic stainless steels including welds from JP9-16

    Energy Technology Data Exchange (ETDEWEB)

    Sawai, T.; Shiba, K.; Hishinuma, A.

    1996-04-01

    Austenitic stainless steels, including specimens taken from various electron beam (EB) welds, have been irradiated in HFIR Phase II capsules, JP9-16. Fifteen specimens irradiated at 300, 400, and 500{degrees}C up to 17 dpa are so far examined by a transmission electron microscope (TEM). In 300{degrees}C irradiation, cavities were smaller than 2nm and different specimens showed little difference in cavity microstructure. At 400{degrees}C, cavity size was larger, but still very small (<8 nm). At 500{degrees}C, cavity size reached 30 nm in weld metal specimens of JPCA, while cold worked JPCA contained a small (<5 nm) cavities. Inhomogeneous microstructural evolution was clearly observed in weld-metal specimens irradiated at 500{degrees}C.

  20. Optical-Thermal Response of Laser-Irradiated Tissue

    CERN Document Server

    Welch, Ashley J

    2011-01-01

    The second edition of 'Optical-Thermal Response of Laser-Irradiated Tissue' maintains the standard of excellence established in the first edition, while adjusting the content to reflect changes in tissue optics and medical applications since 1995. The material concerning light propagation now contains new chapters devoted to electromagnetic theory for coherent light. The material concerning thermal laser-tissue interactions contains a new chapter on pulse ablation of tissue. The medical applications section now includes several new chapters on Optical Coherent Tomography, acoustic imaging, molecular imaging, forensic optics and nerve stimulation. A detailed overview is provided of the optical and thermal response of tissue to laser irradiation along with diagnostic and therapeutic examples including fiber optics. Sufficient theory is included in the book so that it is suitable for a one or two semester graduate or for senior elective courses. Material covered includes: 1. light propagation and diagnostic appl...

  1. Synergies Between ' and Cavity Formation in HT-9 Following High Dose Neutron Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Parish, Chad M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Saleh, Tarik A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Eftink, Benjamin P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-06-01

    Candidate cladding materials for advanced nuclear power reactors including fast reactor designs require materials capable of withstanding high dose neutron irradiation at elevated temperatures. One candidate material, HT-9, through various research programs have demonstrated the ability to withstand significant swelling and other radiation-induced degradation mechanisms in the high dose regime (>50 displacements per atom, dpa) at elevated temperatures (>300 C). Here, high efficiency multi-dimensional scanning transmission electron microscopy (STEM) acquisition with the aid of a three-dimensional (3D) reconstruction and modeling technique is used to probe the microstructural features that contribute to the exceptional swelling resistance of HT-9. In particular, the synergies between ' and fine-scale and moderate-scale cavity formation is investigated.

  2. Development of detection methods for irradiated foods

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Jae Seung; Kim, Chong Ki; Lee, Hae Jung [Korea Atomic Energy Research Insitiute, Taejon (Korea, Republic of); Kim, Kyong Su [Chosun University, Kwangju (Korea, Republic of)

    1999-04-01

    To identify irradiated foods, studies have been carried out with electron spin resonance (ESR) spectroscopy on bone containing foods, such as chicken, pork, and beef. The intensity of the signal induced in bones increased linearly with irradiation doses in the range of 1.0 kGy to 5.0 kGy, and it was possible to distinguish between samples given low and high doses of irradiation. The signal stability for 6 weeks made them ideal for the quick and easy identification of irradiated meats. The analysis of DNA damage made on single cells by agarose gel electrophoresis (DNA 'comet assay') can be used to detect irradiated food. All the samples irradiated with over 0.3 kGy were identified to detect post-irradiation by the tail length of their comets. Irradiated samples showed comets with long tails, and the tail length of the comets increased with the dose, while unirradiated samples showed no or very short tails. As a result of the above experiment, the DNA 'comet assay' might be applied to the detection of irradiated grains as a simple, low-cost and rapid screening test. When fats are irradiated, hydrocarbons contained one or two fewer carbon atoms are formed from the parent fatty acids. The major hydrocarbons in irradiated beef, pork and chicken were 1,7-hexadecadiene and 8-heptadecene originating from leic acid. 1,7 hexadecadiene was the highest amount in irradiated beef, pork and chicken. Eight kinds of hydrocarbons were identified from irradiated chicken, among which 1,7-hexadecadiene and 8-heptadecen were detected as major compounds. The concentration of radiation-induced hydrocarbons was relatively constant during 16 weeks.

  3. Effect of irradiation on the streptococcus mutans

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Ki Dong; Kim, Gyu Tae; Choi, Yong Suk; Hwang, Eui Hwan [Kyung Hee Univ., Seoul (Korea, Republic of)

    2007-03-15

    To observe direct effect of irradiation on cariogenic Streptococcus mutans. S. mutans GS5 was exposed to irradiation with a single absorbed dose of 10, 20, 30, and 40 Gy. Viability and changes in antibiotic sensitivity, morphology, transcription of virulence factors, and protein profile of bacterium after irradiation were examined by pour plate, disc diffusion method, Transmission electron microscopy. RT-PCR, and SDS-PAGE, respectively. After irradiation with 10 and 20 Gy, viability of S. mutans was reduced. Further increase in irradiation dose, however, did not affect the viability of the remaining cells of S. mutans. Irradiated S. mutans was found to have become sensitive to antibiotics. In particular, the bacterium irradiated with 40 Gy increased its susceptibility to cefotaxime, penicillin, and tetracycline. Under the transmission electron microscope, number of morphologically abnormal cells was increased as the irradiation dose was increased. S. mutans irradiated with 10 Gy revealed a change in the cell wall and cell membrane. As irradiation dose was increased. a higher number of cells showed thickened cell wall and cell membrane and lysis, and appearance of ghost cells was noticeable. In RT-PCR, no difference was detected in expression of gtfB and spaP between cells with and without irradiation of 40 Gy. In SDS-PAGE, proteins with higher molecular masses were gradually diminished as irradiation dose was increased. These results suggest that irradiation affects the cell integrity of S. mutans, as observed by SDS-PAGE, and as manifested by the change in cell morphology, antibiotic sensitivity, and eventually viability of the bacterium.

  4. Radiation carcinogenesis in dogs irradiated during prenatal and postnatal development

    Energy Technology Data Exchange (ETDEWEB)

    Benjamin, S.A.; Saunders, W.J.; Angleton, G.M.; Lee, A.C. (Colorado State Univ., Fort Collins, CO (Unites States). Coll. of Veterinary Medicine and Biomedical Sciences)

    1991-12-01

    To evaluate the lifetime hazards of ionizing radiation exposure, 1680 beagles recieved whole-body, 60-cobalt gamma exposures or sham-exposures during development. Eight groups of 120 dogs each recieved mean doses of 16 or 83 cGy at 8 (preimplantation), 28 (embryonic), or 55 (late fetal) days postcoitus (dpc), or 2 (neonatal) days postpartum (dpp). One group of 120 dogs received 83 cGy at 70 dpp (juvenile), and one group of 240 dogs received 83 cGy at 365 dpp (young adult). Sham-irradiations were delivered to 360 controls. Sexes were equally represented. Young dogs, up to 4 years of age, had an increase in benign and malignant neoplasms after irradiation in the perinatal period at 55 dpc or 2 dpp. Among these, 4 fatal cancers were observed. No malignancies occurred in comparably-aged controls. The increase in both fatal neoplasms and all neoplasms in the perinatally-exposed groups were statistically significant. Over the full lifetime, dogs irradiated in the perinatal period also had the strongest evidence for an increased risk for fatal malignancies of all types. Though not as strong, there was a trend for increased risk for fatal cancer in dogs irradiated at all other ages. The risk of fatal malignancy after irradiation was greater in females than in males. Dogs exposed at 55 dpc had a significant increase in lymphoid neoplasia and dogs exposed at 8 and 55 dpc had increased risk for hemangiosarcoma. There was no evidence for an increased risk for mammary carcinoma in irradiated females. Dogs exposed as juveniles at 70 dpp had a significant increase in all benign and malignant thyroid neoplasms, including fatal thyroid carcinoma. (author) 40 refs.

  5. A new irradiation plant in Italy: Technical features and activities performed

    Science.gov (United States)

    Tata, A.; Casali, F.; Schwarz, M.

    1998-06-01

    Since 1995, a new Hitesys Co. pilot/industrial irradiation plant has been operating in Aprilia, 50 km south of Rome. The plant, which was jointly designed by ENEA and Hitesys Co., is equipped with a highly flexible automatic materials transport system which is also suitable for continuous process repetition or, when upturned, for double-side material treatment. The main features of the irradiation plant are: - the radiation source: EB-machine LINAC type (s band) with maximum electron beam energy of 10 MeV and beam power of 1000 W; - the bunker: external type, shielded by ordinary concrete, equipped with a suitable entrance/exit maze in order to allow easy handling and managing of materials as well as to facilitate equipment and machinery maintenance and inspection activities. An intense program of R&D activities and technological services has already been performed in relation to industrial processes and environmental applications, as well as many other radiation technology applications, including agriculture related processes.

  6. Small Specimen Data from a High Temperature HFIR Irradiation Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Burchell, Timothy D [ORNL; McDuffee, Joel Lee [ORNL; Thoms, Kenneth R [ORNL

    2014-01-01

    The HTV capsule is a High Flux Isotope Reactor (HFIR) target-rod capsule designed to operate at very high temperatures. The graphite containing section of the capsule (in core) is approximately 18 inches (457.2 mm) long and is separated into eight temperature zones. The specimen diameters within each zone are set to achieve the desired gas gap and hence design temperature (900 C, 1200 C or 1500 C). The capsule has five zones containing 0.400 inch (10.16 mm) diameter specimens, two zones containing 0.350 inch (8.89 mm) diameter specimens and one zone containing 0.300 inch (7.62 mm) diameter specimens. The zones have been distributed within the experiment to optimize the gamma heating from the HFIR core as well as minimize the axial heat flow in the capsule. Consequently, there are two 900 C zones, three 1200 C zones, and three 1500 C zones within the HTV capsule. Each zone contains nine specimens 0.210 0.002 inches (5.334 mm) in length. The capsule will be irradiated to a peak dose of 3.17 displacements per atom. The HTV specimens include samples of the following graphite grades: SGL Carbon s NBG-17 and NBG-18, GrafTech s PCEA, Toyo Tanso s IG-110, Mersen s 2114 and the reference grade H-451 (SGL Carbon). As part of the pre-irradiation program the specimens were characterized using ASTM Standards C559 for bulk density, and ASTM C769 for approximate Young s modulus from the sonic velocity. The probe frequency used for the determination of time of flight of the ultrasonic signal was 2.25 MHz. Marked volume (specimen diameter) effects were noted for both bulk density (increased with increasing specimen volume or diameter) and Dynamic Young s modulus (decreased with increasing specimen volume or diameter). These trends are extended by adding the property vs. diameter data for unirradiated AGC-1 creep specimens (nominally 12.5 mm-diameter x 25.4 mm-length). The relatively large reduction in Dynamic Young s Modulus was surprising given the trend for increasing density

  7. Fabrication and Comparison of Fuels for Advanced Gas Reactor Irradiation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey Phillips; Charles Barnes; John Hunn

    2010-10-01

    As part of the program to demonstrate TRISO-coated fuel for the Next Generation Nuclear Plant, a series of irradiation tests of Advanced Gas Reactor (AGR) fuel are being performed in the Advanced Test Reactor (ATR) at the Idaho National Laboratory. In the first test, called “AGR-1,” graphite compacts containing approximately 300,000 coated particles were irradiated from December 2006 until November 2009. Development of AGR-1 fuel sought to replicate the properties of German TRISO-coated particles. No particle failures were seen in the nearly 3-year irradiation to a burn up of 19%. The AGR-1 particles were coated in a two-inch diameter coater. Following fabrication of AGR-1 fuel, process improvements and changes were made in each of the fabrication processes. Changes in the kernel fabrication process included replacing the carbon black powder feed with a surface-modified carbon slurry and shortening the sintering schedule. AGR-2 TRISO particles were produced in a six-inch diameter coater using a change size about twenty-one times that of the two-inch diameter coater used to coat AGR-1 particles. Changes were also made in the compacting process, including increasing the temperature and pressure of pressing and using a different type of press. Irradiation of AGR-2 fuel began in late spring 2010. Properties of AGR-2 fuel compare favorably with AGR-1 and historic German fuel. Kernels are more homogeneous in shape, chemistry and density. TRISO-particle sphericity, layer thickness standard deviations, and defect fractions are also comparable. In a sample of 317,000 particles from deconsolidated AGR-2 compacts, 3 exposed kernels were found in a leach test. No SiC defects were found in a sample of 250,000 deconsolidated particles, and no IPyC defects in a sample of 64,000 particles. The primary difference in properties between AGR-1 and AGR-2 compacts is that AGR-2 compacts have a higher matrix density, 1.6 g/cm3 compared to about 1.3 g/cm3 for AGR-1 compacts. Based on

  8. Effect of light irradiation by light emitting diode on colon cancer cells.

    Science.gov (United States)

    Matsumoto, Noriko; Yoshikawa, Kozo; Shimada, Mitsuo; Kurita, Nobuhiro; Sato, Hirohiko; Iwata, Takashi; Higashijima, Jun; Chikakiyo, Motoya; Nishi, Masaaki; Kashihara, Hideya; Takasu, Chie; Eto, Shohei; Takahashi, Akira; Akutagawa, Masatake; Emoto, Takahiro

    2014-09-01

    Recent studies have demonstrated the efficacy of irradiation from light emitting diodes (LED) for wound healing, anti-inflammation and anticancer therapies. However, little is known about the effects of visible light in colon cancer cells. The purpose of this study was to evaluate the biological response (including gene expression changes) of human colon cancer cells to different wavelengths of LED irradiation. Human colon cancer cells (HT29 or HCT116) were seeded onto laboratory dishes that were then put on LED irradiation equipment with a 465 nm-, 525 nm-, or 635 nm-LED. Irradiation at 15 or 30 mW was performed 10 min/day, each day for 5 days. The cell counting kit8 was then used to measure cell viability. Apoptosis and expression of several mRNAs (caspase, MAPK and autophagy pathway) in HT29 cultures irradiated with 465 nm LED were evaluated via AnnexinV/PI and RT-PCR, respectively. Viability of HT29 and HCT116 cells was lower in 465 nm-LED irradiated cultures than in control cultures, but viability of HT29 cells did not differ between control cultures and 525 nm-LED or 635 nm-LED irradiated cultures. Moreover, the expression of FAS, caspase-3, capase-8, and JUK were significantly higher in 465 nm-LED irradiated cultures than in control cultures, and expression of ERK1/2 and LC3 was lower in blue-irradiated cells. LED irradiation at 465 nm inhibited the proliferation of HT29 cells and of HCT116 cells. Notably, LED irradiation at 465 nm promoted apoptosis inHT29 cultures via the extrinsic apoptosis pathway and the MAPK pathway. Copyright© 2014 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  9. Physical and Biological Characterization of the Gamma-Irradiated Human Cornea.

    Science.gov (United States)

    Chae, J Jeremy; Choi, Joseph S; Lee, Justin D; Lu, Qiaozhi; Stark, Walter J; Kuo, Irene C; Elisseeff, Jennifer H

    2015-10-01

    To compare the physical and biological characteristics of commercial gamma-irradiated corneas with those of fresh human corneas and to determine suitability for transplantation. The physical properties of gamma-irradiated and fresh corneas were evaluated with respect to light transmittance, hydration (swelling ratio), elastic modulus (compressive modulus by the indentation method), matrix organization (differential scanning calorimetry), and morphology (light and transmission electron microscopy). The biological properties of the gamma-irradiated cornea, including residual cell content and cellular biocompatibility, were evaluated by quantifying DNA content and measuring the proliferation rate of human corneal epithelial cells, respectively. The hydration, light transmittance, elastic modulus, and proliferation rate of human corneal epithelial cells were not significantly different between fresh and gamma-irradiated corneas. However, differences were observed in tissue morphology, DNA content, and thermal properties. The density of collagen fibrils of the gamma-irradiated corneal sample (160.6 ± 33.2 fibrils/μm) was significantly lower than that of the fresh corneal sample (310.0 ± 44.7 fibrils/μm). Additionally, in the gamma-irradiated corneas, cell fragments-but not viable cells-were observed, supported by lower DNA content of the gamma-irradiated cornea (1.0 ± 0.1 μg/mg) than in fresh corneas (1.9 μg/mg). Moreover, the denaturation temperature of gamma-irradiated corneas (61.8 ± 1.1 °C) was significantly lower than that of fresh corneas (66.1 ± 1.9 °C). Despite structural changes due to irradiation, the physical and biological properties of the gamma-irradiated cornea remain similar to the fresh cornea. These factors, combined with a decreased risk of rejection and longer shelf life, make the gamma-irradiated tissue a viable and clinically desired option in various ophthalmic procedures.

  10. Theory including future not excluded

    DEFF Research Database (Denmark)

    Nagao, K.; Nielsen, H.B.

    2013-01-01

    We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time T and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation......, Ehrenfest's theorem, and the conserved probability current density. In addition,we showthat the expectation value at the present time t of a future-included theory for large T - t and large t - T corresponds to that of a future-not-included theory with a proper inner product for large t - T. Hence, the CAT...

  11. AMS at the ANU including biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Fifield, L.K.; Allan, G.L.; Cresswell, R.G.; Ophel, T.R. [Australian National Univ., Canberra, ACT (Australia); King, S.J.; Day, J.P. [Manchester Univ. (United Kingdom). Dept. of Chemistry

    1993-12-31

    An extensive accelerator mass spectrometry program has been conducted on the 14UD accelerator at the Australian National University since 1986. In the two years since the previous conference, the research program has expanded significantly to include biomedical applications of {sup 26}Al and studies of landform evolution using isotopes produced in situ in surface rocks by cosmic ray bombardment. The system is now used for the measurement of {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36}Cl, {sup 59}Ni and {sup 129}I, and research is being undertaken in hydrology, environmental geochemistry, archaeology and biomedicine. On the technical side, a new test system has permitted the successful off-line development of a high-intensity ion source. A new injection line to the 14UD has been established and the new source is now in position and providing beams to the accelerator. 4 refs.

  12. High gamma-rays irradiation tests of critical components for ITER (International Thermonuclear Experimental Reactor) in-vessel remote handling system

    Energy Technology Data Exchange (ETDEWEB)

    Obara, Kenjiro; Kakudate, Satoshi; Oka, Kiyoshi [Department of Fusion Engineering Research, Naka Fusion Research Establishment, Japan Atomic Energy Research Institute, Naka, Ibaraki (Japan)] [and others

    1999-02-01

    In ITER, the in-vessel remote handling is inevitably required to assemble and maintain the activated in-vessel components due to deuterium and tritium operation. Since the in-vessel remote handling system has to be operated under the intense of gamma ray irradiation, the components of the remote handling system are required to have radiation hardness so as to allow maintenance operation for a sufficient length of time under the ITER in-vessel environments. For this, the Japan, European and Russian Home Teams have extensively conducted gamma ray irradiation tests and quality improvements including optimization of material composition through ITER R and D program in order to develop radiation hard components which satisfy the doses from 10 MGy to 100 MGy at a dose rate of 1 x 10{sup 6} R/h (ITER R and D Task: T252). This report describes the latest status of radiation hard component development which has been conducted by the Japan Home Team in the ITER R and D program. The number of remote handling components tested is about seventy and these are categorized into robotics (Subtask 1), viewing system (Subtask 2) and common components (Subtask 3). The irradiation tests, including commercial base products for screening, modified products and newly developed products to improve the radiation hardness, were carried out using the gamma ray irradiation cells in Takasaki Establishment, JAERI. As a result, the development of the radiation hard components which can be tolerable for high temperature and gamma radiation has been well progressed, and many components, such as AC servo motor with ceramics insulated wire, optical periscope and CCD camera, have been newly developed. (author)

  13. Effects of ion irradiation on microstructure and properties of zirconium alloys—A review

    Directory of Open Access Journals (Sweden)

    Chunguang Yan

    2015-04-01

    Full Text Available Zirconium alloys are widely used in nuclear reactors as structural materials. During the operation, they are exposed to fast neutrons. Ion irradiation is used to simulate the damage introduced by neutron irradiation. In this article, we briefly review the neutron irradiation damage of zirconium alloys, then summarize the effect of ion irradiation on microstructural evolution, mechanical and corrosion properties, and their relationships. The microstructure components consist of dislocation loops, second phase precipitates, and gas bubbles. The microstructure parameters are also included such as domain size and microstrain determined by X-ray diffraction and the S-parameter determined by positron annihilation. Understanding the relationships of microstructure and properties is necessary for developing new advanced materials with higher irradiation tolerance.

  14. Analytical and toxicological studies of decomposition of insecticide parathion after gamma-irradiation and ozonation.

    Science.gov (United States)

    Bojanowska-Czajka, Anna; Torun, Murat; Kciuk, Gabriel; Wachowicz, Mariusz; Ozbay, Dilek Solpan; Guven, Olgun; Bobrowski, Krzysztof; Trojanowicz, Marek

    2012-01-01

    The decomposition of the widely used organophosphorus pesticide parathion was carried out in aqueous solutions by the use of gamma-irradiation from a 60Co source or ozonation by means of an ozone generator, and by combined processes of ozonation and radiolysis. Factors affecting the parathion decomposition as well formation and decomposition of the main by-products, including irradiation dose, length of ozonation time, and presence of common scavengers, were investigated. The most efficient was found to be the gamma-irradiation process combined with a short ozonation period; about 1 kGy irradiation dose was sufficient to decompose the pesticide in 15 mg/L solutions. Chemical studies of the decomposition of parathion were accompanied by monitoring of toxicity changes of irradiated solutions with the Microtox test.

  15. Microdischarge Array Flexible Light Source for High-Efficiency Irradiation of Spaced-Based Crops Project

    Data.gov (United States)

    National Aeronautics and Space Administration — It is desirable to develop a high-efficiency lighting source for large-area irradiation of space-based crops. The key requirements for such a system include high...

  16. LBA-ECO TG-03 Solar Surface Irradiance and PAR, Brazilian Amazon: 1999-2004

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set includes solar surface irradiance from Kipp and Zonen CM-21 pyranometers, both total unfiltered and filtered (RG695), and photosynthetically active...

  17. LBA-ECO TG-03 Solar Surface Irradiance and PAR, Brazilian Amazon: 1999-2004

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: This data set includes solar surface irradiance from Kipp and Zonen CM-21 pyranometers, both total unfiltered and filtered (RG695), and photosynthetically...

  18. Outcome in patients with small cell lung cancer re-irradiated for brain metastases after prior prophylactic cranial irradiation.

    Science.gov (United States)

    Bernhardt, Denise; Bozorgmehr, Farastuk; Adeberg, Sebastian; Opfermann, Nils; von Eiff, Damian; Rieber, Juliane; Kappes, Jutta; Foerster, Robert; König, Laila; Thomas, Michael; Debus, Jürgen; Steins, Martin; Rieken, Stefan

    2016-11-01

    Patients with brain metastases from small-cell lung cancer (SCLC) who underwent prior prophylactic cranial irradiation (PCI) are often treated with a second course of whole brain radiation therapy (Re-WBRT) or stereotactic radiosurgery (SRS) for purposes of palliation in symptomatic patients, hope for increased life expectancy or even as an alternative to untolerated steroids. Up to date there is only limited data available regarding the effect of this treatment. This study examines outcomes in patients in a single institution who underwent cerebral re-irradiation after prior PCI. We examined the medical records of 76 patients with brain metastases who had initially received PCI between 2008 and 2015 and were subsequently irradiated with a second course of cerebral radiotherapy. Patients underwent re-irradiation using either Re-WBRT (88%) or SRS (17%). The outcomes, including symptom palliation, radiation toxicity, and overall survival (OS) following re-irradiation were analyzed. Survival and correlations were calculated using log-rank, univariate, and multivariate Cox proportional hazards-ratio analyses. Treatment-related toxicity was classified according to CTCAE v4.0. Median OS of all patients was 3 months (range 0-12 months). Median OS after Re-WBRT was 3 months (range 0-12 months). Median OS after SRS was 5 months (range 0-12 months). Karnofsky performance status scale (KPS ≥50%) was significantly associated with improved OS in both univariate (HR 2772; p=0,009) and multivariate analyses (HR 2613; p=0,024) for patients receiving Re-WBRT. No unexpected toxicity was observed and the observed toxicity remained consistently low. Symptom palliation was achieved in 40% of symptomatic patients. In conclusion, cerebral re-irradiation after prior PCI is beneficial for symptom palliation and is associated with minimal side effects in patients with SCLC. Our survival data suggests that it is primarily useful in patients with adequate performance status. Copyright

  19. Implementation of irradiation of pork for trichina control

    Energy Technology Data Exchange (ETDEWEB)

    Engel, R.E.; Post, A.R.; Post, R.C. (Department of Agriculture, Washington, DC (USA))

    1988-07-01

    This article describes the attempts to develop adequate regulatory framework for the use of ionizing radiations in the preservation of food. To be successful, a uniform set of guidelines are needed for the selection, calibration, and application of dosimetry systems; clearance of packaging materials; labeling information; and consumer education programs are essential. The primary regulatory agency that food processors must satisfy is the US FDA. In 1985, in response to an industry petition, the FDA amended its food additive regulations to permit the use of gamma radiation sources to irradiate fresh, non-heat processed pork cuts or carcasses to control Trichinellaspiralis. The regulation permits irradiation of only fresh pork within a dose range of 0.3 to 1 kGy.

  20. Tritium release from irradiated lithium aluminate, can it be improved

    Energy Technology Data Exchange (ETDEWEB)

    Kopasz, J.P.; Seils, C.A.; Johnson, C.E.

    1991-01-01

    Lithium aluminate is an attractive material (in terms of its chemical, mechanical and irradiation properties) for breeding tritium in fusion reactors; however, its tritium release characteristics are not as good as those of other candidate materials. To investigate whether tritium release from lithium aluminate can be improved, we have studied the tritium release from irradiated samples of pure lithium aluminate, lithium aluminate doped with Mg, and lithium aluminate with a surface deposit of platinum. The release was studied by the temperature programmed desorption (TPD) method. Both the platinum coating and magnesium doping were found to improve the tritium release characteristics, as determined by TPD. Tritium release shifted to states with lower activation energies for the altered materials.

  1. Tritium release from irradiated lithium aluminate, can it be improved?

    Energy Technology Data Exchange (ETDEWEB)

    Kopasz, J.P.; Seils, C.A.; Johnson, C.E.

    1991-12-31

    Lithium aluminate is an attractive material (in terms of its chemical, mechanical and irradiation properties) for breeding tritium in fusion reactors; however, its tritium release characteristics are not as good as those of other candidate materials. To investigate whether tritium release from lithium aluminate can be improved, we have studied the tritium release from irradiated samples of pure lithium aluminate, lithium aluminate doped with Mg, and lithium aluminate with a surface deposit of platinum. The release was studied by the temperature programmed desorption (TPD) method. Both the platinum coating and magnesium doping were found to improve the tritium release characteristics, as determined by TPD. Tritium release shifted to states with lower activation energies for the altered materials.

  2. Irradiation test facility of the HTTR and possible international cooperation

    Energy Technology Data Exchange (ETDEWEB)

    Sanokawa, Konomo; Fujishoro, Toshio; Arai, Taketoshi; Miyamoto, Yoshiaki; Tanaka, Toshiyuki; Shiozawa, Shusaku [Oarai Research Establishment, Japan Atomic Energy Research Institute JAERI, Ibaraki-ken (Japan)

    1998-09-01

    The HTTR (High Temperature Engineering Test Reactor) is a high temperature gas-cooled reactor with a maximum helium coolant temperature of 950C at the reactor outlet. The construction of the HTTR started in March 1991 and its first criticality will be attained very soon. All of the components of the HTTR except fuels has been installed and an overall functional test of the components is under way. Fuel fabrication was finished and is ready to be installed in the reactor core. The HTTR project is intended to establish and upgrade the technology basis necessary for HTGR developments. At the same time new materials development, etc., are also planned for innovative basic research using the HTTR test facility. This paper describes the construction status of the HTTR, planned irradiation test facilities and possible international cooperation on irradiation test programs using the HTTR

  3. Environmental application of cesium-137 irradiation technology: Sludges and foods

    Science.gov (United States)

    Sivinski, Jacek S.

    Several activities have been undertaken to investigate and implement the use of the military byproduct cesium-137 in ways which benefit mankind. Gamma radiation from cesium-137 has been shown to be effective in reducing pathogens in sewage sludge to levels where reuse of the material in public areas meets current regulatory criteria for protection of public health. Food irradiation at doses of 10 kGy or less have been found by international expert committees to be wholesome and safe for human consumption. Cesium-137 can be used as a means of enhancing particular properties of various food commodities by means of sterilization, insect disinfestation, delayed senescence and ripening, and sprout inhibition. This paper discusses the U.S. Department of Energy Beneficial Uses Program research and engineering history, as well as current activities and future plans, relating to both sewage sludge and food irradiation.

  4. TEM Examination of Advanced Alloys Irradiated in ATR

    Energy Technology Data Exchange (ETDEWEB)

    Jian Gan, PhD

    2007-09-01

    Successful development of materials is critical to the deployment of advanced nuclear power systems. Irradiation studies of candidate materials play a vital role for better understanding materials performance under various irradiation environments of advanced system designs. In many cases, new classes of materials have to be investigated to meet the requirements of these advanced systems. For applications in the temperature range of 500 800ºC which is relevant to the fast neutron spectrum burner reactors for the Global Nuclear Energy Partnership (GNEP) program, oxide dispersion strengthened (ODS) and ferritic martensitic steels (e.g., MA957 and others) are candidates for advanced cladding materials. In the low temperature regions of the core (<600ºC), alloy 800H, HCM12A (also called T 122) and HT 9 have been considered.

  5. Advanced Post-Irradiation Examination Capabilities Alternatives Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Jeff Bryan; Bill Landman; Porter Hill

    2012-12-01

    An alternatives analysis was performed for the Advanced Post-Irradiation Capabilities (APIEC) project in accordance with the U.S. Department of Energy (DOE) Order DOE O 413.3B, “Program and Project Management for the Acquisition of Capital Assets”. The Alternatives Analysis considered six major alternatives: ? No Action ? Modify Existing DOE Facilities – capabilities distributed among multiple locations ? Modify Existing DOE Facilities – capabilities consolidated at a few locations ? Construct New Facility ? Commercial Partnership ? International Partnerships Based on the alternatives analysis documented herein, it is recommended to DOE that the advanced post-irradiation examination capabilities be provided by a new facility constructed at the Materials and Fuels Complex at the Idaho National Laboratory.

  6. PIE on Safety-Tested Loose Particles from Irradiated Compact 4-4-2

    Energy Technology Data Exchange (ETDEWEB)

    Hunn, John D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gerczak, Tyler J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Morris, Robert Noel [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Baldwin, Charles A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Montgomery, Fred C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-04-01

    Post-irradiation examination (PIE) is being performed in support of tristructural isotropic (TRISO) coated particle fuel development and qualification for High Temperature Gas-cooled Reactors (HTGRs). This work is sponsored by the Department of Energy Office of Nuclear Energy (DOE-NE) through the Advanced Reactor Technologies (ART) Office under the Advanced Gas Reactor Fuel Development and Qualification (AGR) Program. The AGR-1 experiment was the first in a series of TRISO fuel irradiation tests initiated in 2006. The AGR-1 TRISO particles and fuel compacts were fabricated at Oak Ridge National Laboratory (ORNL) in 2006 using laboratory-scale equipment and irradiated for 3 years in the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL) to demonstrate and evaluate fuel performance under HTGR irradiation conditions. Post-irradiation examination was performed at INL and ORNL to study how the fuel behaved during irradiation, and to test fuel performance during exposure to elevated temperatures at or above temperatures that could occur during a depressurized conduction cooldown event. This report summarizes safety testing and post-safety testing PIE conducted at ORNL on loose particles extracted from irradiated AGR-1 Compact 4-4-2.

  7. Charge Transport in Non-Irradiated and Irradiated Silicon Diodes

    CERN Document Server

    Leroy, C; Casse, G L; Glaser, M; Grigoriev, E; Lemeilleur, F

    1999-01-01

    A model describing the transport of charge carriers generated in silicon detectors (standard planar float zone and MESA diodes) by ionizing particles is presented. The current pulse response induced by $\\alpha$ and $\\beta$ particles in non-irradiated detectors and detectors irradiated up to fluences $\\Phi \\approx 3 \\cdot 10^{14}$ particles/cm$^2$ is reproduced through this model: i) by adding a small n-type region 15 $\\mu$m deep on the $p^+$ side for the standard planar float zone detectors at fluences beyond the n to p-type inversion and ii) for the MESA detectors, by considering one dead layer 14 $\\mu$m deep (observed experimentally) on each side, and introducing a second (delayed) component. For both types of detectors, the model gives mobilities decreasing linearily up to fluences of about $5 \\cdot 10^{13}$ particles/cm$^2$ and converging, beyond, to saturation values of about 1000 cm$^2$/Vs and 455 cm$^2$/Vs for electrons and holes, respectively. At a fluence $\\Phi \\approx 10^{14}$ particles/cm$^2$, char...

  8. Thermal analysis applied to irradiated propolis

    Science.gov (United States)

    Matsuda, Andrea Harumi; Machado, Luci Brocardo; del Mastro, Nélida Lucia

    2002-03-01

    Propolis is a resinous hive product, collected by bees. Raw propolis requires a decontamination procedure and irradiation appears as a promising technique for this purpose. The valuable properties of propolis for food and pharmaceutical industries have led to increasing interest in its technological behavior. Thermal analysis is a chemical analysis that gives information about changes on heating of great importance for technological applications. Ground propolis samples were 60Co gamma irradiated with 0 and 10 kGy. Thermogravimetry curves shown a similar multi-stage decomposition pattern for both irradiated and unirradiated samples up to 600°C. Similarly, through differential scanning calorimetry , a coincidence of melting point of irradiated and unirradiated samples was found. The results suggest that the irradiation process do not interfere on the thermal properties of propolis when irradiated up to 10 kGy.

  9. Thermal analysis applied to irradiated propolis

    Energy Technology Data Exchange (ETDEWEB)

    Matsuda, Andrea Harumi; Machado, Luci Brocardo; Mastro, N.L. del E-mail: nelida@usp.br

    2002-03-01

    Propolis is a resinous hive product, collected by bees. Raw propolis requires a decontamination procedure and irradiation appears as a promising technique for this purpose. The valuable properties of propolis for food and pharmaceutical industries have led to increasing interest in its technological behavior. Thermal analysis is a chemical analysis that gives information about changes on heating of great importance for technological applications. Ground propolis samples were {sup 60}Co gamma irradiated with 0 and 10 kGy. Thermogravimetry curves shown a similar multi-stage decomposition pattern for both irradiated and unirradiated samples up to 600 deg. C. Similarly, through differential scanning calorimetry , a coincidence of melting point of irradiated and unirradiated samples was found. The results suggest that the irradiation process do not interfere on the thermal properties of propolis when irradiated up to 10 kGy.

  10. AGR 3/4 Irradiation Test Final As Run Report

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-06-01

    Several fuel and material irradiation experiments have been planned for the Idaho National Laboratory Advanced Reactor Technologies Technology Development Office Advanced Gas Reactor Fuel Development and Qualification Program (referred to as the INL ART TDO/AGR fuel program hereafter), which supports the development and qualification of tristructural-isotropic (TRISO) coated particle fuel for use in HTGRs. The goals of these experiments are to provide irradiation performance data to support fuel process development, qualify fuel for normal operating conditions, support development and validation of fuel performance and fission product transport models and codes, and provide irradiated fuel and materials for post irradiation examination and safety testing (INL 05/2015). AGR-3/4 combined the third and fourth in this series of planned experiments to test TRISO coated low enriched uranium (LEU) oxycarbide fuel. This combined experiment was intended to support the refinement of fission product transport models and to assess the effects of sweep gas impurities on fuel performance and fission product transport by irradiating designed-to-fail fuel particles and by measuring subsequent fission metal transport in fuel-compact matrix material and fuel-element graphite. The AGR 3/4 fuel test was successful in irradiating the fuel compacts to the burnup and fast fluence target ranges, considering the experiment was terminated short of its initial 400 EFPD target (Collin 2015). Out of the 48 AGR-3/4 compacts, 42 achieved the specified burnup of at least 6% fissions per initial heavy-metal atom (FIMA). Three capsules had a maximum fuel compact average burnup < 10% FIMA, one more than originally specified, and the maximum fuel compact average burnup was <19% FIMA for the remaining capsules, as specified. Fast neutron fluence fell in the expected range of 1.0 to 5.5×1025 n/m2 (E >0.18 MeV) for all compacts. In addition, the AGR-3/4 experiment was globally successful in keeping the

  11. Advanced Reactors Transition program fiscal year 1998 multi-year work plan

    Energy Technology Data Exchange (ETDEWEB)

    Gantt, D.A.

    1997-09-25

    The mission of the Advanced Reactors Transition program is two-fold. First, the program is to maintain the Fast Flux Test Facility (FFTF) and the Fuels and Materials Examination Facility (FMEF) in Standby to support a possible future role in the tritium production strategy. Secondly, the program is to continue deactivation activities which do not conflict with the Standby directive. On-going deactivation activities include the processing of non-usable, irradiated, FFTF components for storage or disposal; deactivation of Nuclear Energy legacy test facilities; and deactivation of the Plutonium Recycle Test Reactor (PRTR) facility, 309 Building.

  12. In Situ TEM Multi-Beam Ion Irradiation as a Technique for Elucidating Synergistic Radiation Effects

    Directory of Open Access Journals (Sweden)

    Caitlin Anne Taylor

    2017-09-01

    Full Text Available Materials designed for nuclear reactors undergo microstructural changes resulting from a combination of several environmental factors, including neutron irradiation damage, gas accumulation and elevated temperatures. Typical ion beam irradiation experiments designed for simulating a neutron irradiation environment involve irradiating the sample with a single ion beam and subsequent characterization of the resulting microstructure, often by transmission electron microscopy (TEM. This method does not allow for examination of microstructural effects due to simultaneous gas accumulation and displacement cascade damage, which occurs in a reactor. Sandia’s in situ ion irradiation TEM (I3TEM offers the unique ability to observe microstructural changes due to irradiation damage caused by concurrent multi-beam ion irradiation in real time. This allows for time-dependent microstructure analysis. A plethora of additional in situ stages can be coupled with these experiments, e.g., for more accurately simulating defect kinetics at elevated reactor temperatures. This work outlines experiments showing synergistic effects in Au using in situ ion irradiation with various combinations of helium, deuterium and Au ions, as well as some initial work on materials utilized in tritium-producing burnable absorber rods (TPBARs: zirconium alloys and LiAlO2.

  13. Changes in volatile compounds of gamma-irradiated fresh cilantro leaves during cold storage.

    Science.gov (United States)

    Fan, Xuetong; Sokorai, Kimberly J B

    2002-12-18

    Consumption of salsas and dishes containing cilantro has been linked to several recent outbreaks of food-borne illness due to contamination with human pathogens. Ionizing irradiation can effectively eliminate food-borne pathogens from various vegetables including cilantro. However, the effect of irradiation on aroma of fresh cilantro is unknown. This study was conducted to investigate the effect of irradiation on volatile compounds of fresh cilantro leaves. Fresh cilantro leaves (Coriandrum sativum L) were irradiated with 0, 1, 2, or 3 kGy gamma radiation and then stored at 3 degrees C up to 14 days. Volatile compounds were extracted using solid-phase microextraction (SPME), followed by gas chromatographic separation and mass spectra detection at 0, 3, 7, and 14 days after irradiation. Most of the volatile compounds identified were aldehydes. Decanal and (E)-2-decenal were the most abundant compounds, accounting for more than 80% of the total amount of identified compounds. The amounts of linalool, dodecanal, and (E)-2-dodecenal in irradiated samples were significantly lower than those in nonirradiated samples at day 14. However, the most abundant compounds [decanal and (E)-2-decenal] were not consistently affected by irradiation. During storage at 3 degrees C, the amount of most aldehydes peaked at 3 days and then decreased afterward. Our results suggest irradiation of fresh cilantro for safety enhancement at doses up to 3 kGy had minimal effect on volatile compounds compared with the losses that occurred during storage.

  14. Improved calculation of displacements per atom cross section in solids by gamma and electron irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Piñera, Ibrahin, E-mail: ipinera@ceaden.edu.cu [Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, CEADEN, 30 St. 502, Playa 11300, Havana (Cuba); Cruz, Carlos M.; Leyva, Antonio; Abreu, Yamiel; Cabal, Ana E. [Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, CEADEN, 30 St. 502, Playa 11300, Havana (Cuba); Espen, Piet Van; Remortel, Nick Van [University of Antwerp, CGB, Groenenborgerlaan 171, 2020 Antwerpen (Belgium)

    2014-11-15

    Highlights: • We present a calculation procedure for dpa cross section in solids under irradiation. • Improvement about 10–90% for the gamma irradiation induced dpa cross section. • Improvement about 5–50% for the electron irradiation induced dpa cross section. • More precise results (20–70%) for thin samples irradiated with electrons. - Abstract: Several authors had estimated the displacements per atom cross sections under different approximations and models, including most of the main gamma- and electron-material interaction processes. These previous works used numerical approximation formulas which are applicable for limited energy ranges. We proposed the Monte Carlo assisted Classical Method (MCCM), which relates the established theories about atom displacements to the electron and positron secondary fluence distributions calculated from the Monte Carlo simulation. In this study the MCCM procedure is adapted in order to estimate the displacements per atom cross sections for gamma and electron irradiation. The results obtained through this procedure are compared with previous theoretical calculations. An improvement in about 10–90% for the gamma irradiation induced dpa cross section is observed in our results on regard to the previous evaluations for the studied incident energies. On the other hand, the dpa cross section values produced by irradiation with electrons are improved by our calculations in about 5–50% when compared with the theoretical approximations. When thin samples are irradiated with electrons, more precise results are obtained through the MCCM (in about 20–70%) with respect to the previous studies.

  15. The effect of electron beam irradiation on lipid oxidation in sausages

    Directory of Open Access Journals (Sweden)

    atefeh yousefi

    2017-09-01

    Full Text Available Introduction: Irradiation treatment is one of the best techniques to extend the shelf-life of meat, without emerging the nutritional properties and sensory quality of irradiated meat products.  However electron -beam  may cause transformations in foods but has been known as to the most easily-applied irradiation technique in food industries. Electron-beam irradiation is an environment friendly, low cost and time effective alternative to other decontamination technologies. Lipid oxidation could produce of irradiated meat. This study aimed at evaluating the state of lipid oxidation of irradiated sausages. Its findings could help the control, improve food safety and quality properties to food industries. Methods: Sausages were purchased in a local supermarket, minced sausages blended for thiobarbituric acid reactive substances (TBARS analysis and divided into 25 g pieces. The samples including one control group and four case groups. Packaged sausage were exposed at doses of 0 (control, 1, 2, 3 and 5 kGy and analyzed on various days 0, 5, 10 and 30. Results: Thiobarbituric acid reactive substances (TBARS has increased as time goes on (P<0.05. A significant relationship was observed on different Doses. But, the maximum of TBARS was observed in 3 kGy. Conclusion: Utilizing of Electron-beam irradiation in low doses does not have significant difference on lipid oxidation. Irradiating of meat products by addition of antioxidants can minimize or avoid the development of rancidity.

  16. Lymphangioma secondary to irradiation after mastectomy

    OpenAIRE

    Oliveti,Aline; Biasi, Tatiana Basso; Funchal, Gabriella Di Giunta

    2017-01-01

    Abstract Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation causes the appearance of asymptomatic hyaline vesicles on the irradiated skin. The present report describes a 78-year-old female patient, who initially presented hyaline vesicles that progressed into mult...

  17. Food Irradiation Update and Cost Analysis

    Science.gov (United States)

    1991-11-01

    spices in the United States. In Japan, 10,000 tons of potatoes are irradiated each year to prevent sprouting (chemical treatments to inhibit potato... irradiation can extend the shelf life of refrigerated products, which reduces losses due to spoilage. It can also greatly reduce the pathogens in foods...AD-A273 506 ýil il lit i i1 ii , TECHNICAL REPORT AD NATICK /TR-92 / 002 FOOD IRRADIATION UPDATE-,. .•0 , AND COST ANALYSIS f. .• By Robert T

  18. Resistance of acrylic vessel to gamma irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Carneiro, Andre Cavalcanti; Menezes, Maria Angela de B.C.; Pereira, Marcio Tadeu; Rocha, Nirlando Antonio; Vilela, Jefferson Jose, E-mail: andreccarneiro@gmail.com, E-mail: menezes@cdtn.br, E-mail: mtp@cdtn.br, E-mail: nar@cdtn.br, E-mail: jjv@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Braga, Mario Roberto Martins S.S., E-mail: mariomartins@gmail.com [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Programa de Pos-Graduacao em Ciencias e Tecnicas Nucleares

    2013-07-01

    This paper describes the preliminary studies made in acrylic material in order to verify the effects of radiolysis in acrylic recipients in which the uranium ore standards are conditioned and check if the material is able to keep the {sup 222}Rn inside the vessel. The preliminary results after gamma irradiation of two kinds of recipients indicate no differences between the vessels irradiated and the ones no irradiated, related to color changes and tension resistance. (author)

  19. Squamous cell carcinoma in situ after irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kambara, Takeshi; Nishiyama, Takafumi; Yamada, Rie; Nagatani, Tetsuo; Nakajima, Hiroshi [Yokohama City Univ. (Japan). School of Medicine; Sugiyama, Asami

    1997-12-31

    We report two cases with Squamous Cell Carcinoma (SCC) in situ caused by irradiation to hand eczemas, resistant to any topical therapies. Both of our cases clinically show palmer sclerosis and flexor restriction of the fingers, compatible to chronic radiation dermatitis. Although SCC arising in chronic radiation dermatitis is usually developed ten to twenty years after irradiation, in our cases SCC were found more than forty years after irradiation. (author)

  20. Low-dose X-ray irradiation promotes osteoblast proliferation, differentiation and fracture healing.

    Directory of Open Access Journals (Sweden)

    Ming Chen

    Full Text Available Great controversy exists regarding the biologic responses of osteoblasts to X-ray irradiation, and the mechanisms are poorly understood. In this study, the biological effects of low-dose radiation on stimulating osteoblast proliferation, differentiation and fracture healing were identified using in vitro cell culture and in vivo animal studies. First, low-dose (0.5 Gy X-ray irradiation induced the cell viability and proliferation of MC3T3-E1 cells. However, high-dose (5 Gy X-ray irradiation inhibited the viability and proliferation of osteoblasts. In addition, dynamic variations in osteoblast differentiation markers, including type I collagen, alkaline phosphatase, Runx2, Osterix and osteocalcin, were observed after both low-dose and high-dose irradiation by Western blot analysis. Second, fracture healing was evaluated via histology and gene expression after single-dose X-ray irradiation, and low-dose X-ray irradiation accelerates fracture healing of closed femoral fractures in rats. In low-dose X-ray irradiated fractures, an increase in proliferating cell nuclear antigen (PCNA-positive cells, cartilage formation and fracture calluses was observed. In addition, we observed more rapid completion of endochondral and intramembranous ossification, which was accompanied by altered expression of genes involved in bone remodeling and fracture callus mineralization. Although the expression level of several osteoblast differentiation genes was increased in the fracture calluses of high-dose irradiated rats, the callus formation and fracture union were delayed compared with the control and low-dose irradiated fractures. These results reveal beneficial effects of low-dose irradiation, including the stimulation of osteoblast proliferation, differentiation and fracture healing, and highlight its potential translational application in novel therapies against bone-related diseases.