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Sample records for program friday harbor

  1. Proceedings of the Predator-Prey Modeling Workshop : Workshop Proceedings May 16-19, 1989, University of Washington Friday Harbor Laboratory in Friday Harbor, Washington.

    Energy Technology Data Exchange (ETDEWEB)

    Fickeisen, Duane H.; Dauble, Dennis D.; Neitzel, D.A.

    1989-09-01

    This report summarizes the results of a workshop held to receive expert advice and review existing Columbia River models that include juvenile salmonid predation components and, if warranted, recommend alternate modeling approaches. The workshop was limited to models or modeling approaches that may have practical application to the specific problems of increasing survival of juvenile salmonids in the Columbia and Snake rivers by reducing predation losses. The US Fish and Wildlife Service (FWS) and the Oregon Department of Fish and Wildlife (ODFW) under interagency agreements with the Bonneville Power Administration (BPA) conducted a multi-year study of the impact of predator populations on juvenile salmonids in the John Day Reservoir of the Columbia River. The studies were part of BPA's implementation of the Northwest Power Planning Council's (NPPC) Fish and Wildlife Program, designed to protect and enhance production of salmon as mitigation for losses caused by hydroelectric development. The FWS agreement with BPA includes provisions for refinement or development of models to understand the dynamics of predation on juvenile salmon as a basis for considering active intervention to reduce predation losses. The BPA sponsored the workshop that included a review of existing and proposed modeling approaches, identification of model development needs, and identification of data needs to support modeling efforts. Pacific Northwest Laboratory (PNL) provided workshop design, facilitation, and support services including preparation of this summary. 16 refs., 15 figs., 5 tabs.

  2. Black Friday = Broget Branding?

    DEFF Research Database (Denmark)

    Hansen, Heidi

    2015-01-01

    Black Friday er et godt eksempel på, hvordan ikke kun produktbrands og corporate brands rejser på tværs af landegrænser, men også traditioner som Halloween, Valentines Day og i dette tilfælde den ultimative tilbuds-fredag, som i USA går under navnet Black Friday. Men hvad er Black Friday i Danmark...

  3. Friday Night Pearls of Wisdom

    Directory of Open Access Journals (Sweden)

    Thomas Leabhart

    2012-05-01

    Full Text Available This text testifies to the pedagogy of Etienne Decroux and, in particular, to his lessons in the early 1970s in the blue basement of his house on the outskirts of Paris. The author presents peculiarities of the teaching of mime with emphasis on Decroux’s theatrical improvisation lessons taught every Friday night, and discusses the ambiguities and the power of Decroux’s thought and contributions to contemporary theatre, especially to acting pedagogy.

  4. Lights, Camera, Action... It's "Science Friday"!

    Science.gov (United States)

    Tugurian, Linda; Blanchard, Margaret R.

    2010-01-01

    "Science Friday's" motto "Making Science User-Friendly" was the authors' inspiration, as was its format for a segment on the morning broadcast at Forest View Elementary School. Patterned after National Public Radio's "Science Friday," this special feature was designed to provide an opportunity for budding scientists to communicate their…

  5. 78 FR 79201 - Medicare and State Health Care Programs: Fraud and Abuse; Electronic Health Records Safe Harbor...

    Science.gov (United States)

    2013-12-27

    ... 1001 Medicare and State Health Care Programs: Fraud and Abuse; Electronic Health Records Safe Harbor...; Electronic Health Records Safe Harbor Under the Anti-Kickback Statute AGENCY: Office of Inspector General...) amends the safe harbor regulation concerning electronic health records items and services, which defines...

  6. The New Bedford Harbor Superfund site long-term monitoring program (1993-2009).

    Science.gov (United States)

    Nelson, William G; Bergen, Barbara J

    2012-12-01

    New Bedford Harbor (NBH), located in southeastern Massachusetts, was designated as a marine Superfund site in 1983 due to sediment contamination by polychlorinated biphenyls (PCBs). Based on risks to human health and the environment, the first two phases of the site cleanup involved dredging PCB-contaminated sediments from the harbor. Therefore, a long-term monitoring program (LTM) was developed to measure spatial and temporal chemical and biological changes in sediment, water, and biota to assess the effects and effectiveness of the remedial activities. A systematic, probabilistic sampling design was used to select sediment sampling stations. This unbiased design allowed the three segments of the harbor to be compared spatially and temporally to quantify changes resulting from dredging the contaminated sediments. Sediment was collected at each station, and chemical (e.g., PCBs and metals), physical (e.g., grain size), and biological (e.g., benthic community) measurements were conducted on all samples. This paper describes the overall NBH-LTM approach and the results from the five rounds of sample collections. There is a decreasing spatial gradient in sediment PCB concentrations from the northern boundary (upper harbor) to the southern boundary (outer harbor) of the site. Along this same transect, there is an increase in biological condition (e.g., benthic community diversity). Temporally, the contaminant and biological gradients have been maintained since the 1993 baseline collection; however, since the onset of full-scale remediation, PCB concentrations have decreased throughout the site, and one of the benthic community indices has shown significant improvement in the lower and outer harbor areas.

  7. A spiritual sleepiness scale: the Friday prayer.

    Science.gov (United States)

    Abouda, Maher; Turki, Senda; Hachicha, Amani; Yangui, Ferdaous; Triki, Miriam; Charfi, Med Ridha

    2016-03-01

    Excessive daytime sleepiness (EDS) affects 5% to 20% of the population and is involved in a large number of traffic accidents. EDS is a major symptom in sleep disorders, especially obstructive sleep apnea syndrome (OSA). The daytime sleepiness is evaluated subjectively using scales and questionnaires based on perception. This study is aimed to build a new questionnaire more suited to our lifestyle and then to compare it to the Epworth sleepiness scales (ESS). We administered to 91 adult's patients (76 men and 15 women) consulting for sleep disturbance the ESS and a single subjective question tendency to drowsiness during the Friday prayer. Patients were listed in four groups according to their response to the question «During the past month, have you ever doze or fall asleep during the sermon of the Friday prayer? » By G1 never dozes, G2 low chance of falling asleep, G3 average chance of dozing, G4 high chance of falling asleep. Only 63 patients (58 men and 5 women) responded to both questionnaires. Group 1 included 14 patients with a ESS of 5.5 +/- 1.8, Group 2 included 18 patients with a ESS of 7.3 +/- 1.9, Group 3 included 18 patients with a ESS of 11.05 +/- 2 and Group 4 included 13 patients with a ESS of 14.69 +/- 2.3. The Rho correlation coefficient was high (0.86) and shows a strong correlation between the Results of the two questionnaires. the answer to the question " During the past month, have you ever doze or fall asleep during the sermon of the Friday prayer? » seems to be an appropriate Sleepiness Scale among Muslim patients.

  8. 78 FR 21314 - Medicare and State Health Care Programs: Fraud and Abuse; Electronic Health Records Safe Harbor...

    Science.gov (United States)

    2013-04-10

    ... Programs: Fraud and Abuse; Electronic Health Records Safe Harbor Under the Anti-Kickback Statute AGENCY...). Additionally, we considered whether removing this condition would increase the risk of fraud or abuse posed by... Committee on Science and Technology, available at http://science.house.gov/sites/republicans.science.house...

  9. McNary Dam, Ice Harbor Dam, and Lower Monumental Dam Smolt Monitoring Program; 1996 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Hillson, Todd; Lind, Sharon; Price, William (Washington Department of Fish and Wildlife, Olympia, WA)

    1997-07-01

    The Washington Department of Fish & Wildlife (WDFW) assumed responsibility for the Smolt Monitoring Program at McNary Dam on the Columbia River in 1990 and at the new juvenile collection facility at Lower Monumental Dam on the Snake River in 1993. In 1996, Smolt Monitoring Program activities also began at the new juvenile collection facility located at Ice Harbor Dam. This report summarizes the 1996 Smolt Monitoring work at all three sites. The work at Ice Harbor consisted of Gas Bubble Trauma (GBT) monitoring only. In general, the 1996 passage season at both the McNary and Lower Monumental sites can be characterized by reduced passage of juveniles through the collection systems due to elevated river flows and spill, and low (<1%) overall facility mortality rates most likely resulting from cooler water temperatures. In accordance with the National Marine Fisheries Service recommendations (NMFS, 1995) all spring migrants were bypassed at McNary Dam in 1996. Mechanical problems within the McNary collection system resulted in collection and sampling activities being delayed until April 18 at this site, while sampling and collection began on the scheduled starting date of April 1 at Lower Monumental Dam. Monitoring operations were conducted through December 14 at McNary Dam and through October 28 at Lower Monumental Dam. An ongoing transportation evaluation summer migrant marking program was conducted at McNary Dam in 1996 by the NMFS. This necessitated the sampling of 394,211 additional fish beyond the recommended sampling guidelines. All total, 509,237 and 31,219 juvenile salmonids were anesthetized and individually counted, examined for scale loss, injuries, and brands by WDFW Smolt Monitoring personnel in 1996 at McNary Dam and Lower Monumental Dam, respectively.

  10. YouTube Fridays: Engaging the Net Generation in 5 Minutes a Week

    Science.gov (United States)

    Liberatore, Matthew W.

    2010-01-01

    YouTube Fridays is a teaching tool that devotes the first five minutes of class each Friday to a YouTube video related to the course. Students select the videos, which expand the class's educational content in courses such as thermodynamics and material and energy balances. From assessments of two pilot studies using YouTube Fridays in Chemical…

  11. Stock returns and Friday the 13th effect in five African countries ...

    African Journals Online (AJOL)

    This study is concerned with Friday the 13th and daily stock market returns in five African countries. Using the MSCI Global Equity Indices during various periods, the evidence overwhelmingly suggests that there is no Friday the 13th effect. Keywords: Friday the 13th, stock returns, anomalies, Africa ...

  12. Friday the 13th: The Empirics of Bad Luck

    OpenAIRE

    Fidrmuc, Jan; J.D.Tena

    2014-01-01

    We use the UK Labor Force survey to investigate whether the socio-economic outcomes of people born on the 13th day of the month, and of those born on Friday the 13th, differ from the outcomes of people born on more auspicious days. In many European countries, including the UK, such days are considered unlucky. We consider outcomes that are unlikely to be affected by behavioral adjustments yet which are of considerable importance to one’s quality of life: employment, earnings and marriage. W...

  13. Data Analysis and Data-Driven Decision-Making Strategies Implemented by Elementary Teachers in Selected Exited Program Improvement Safe Harbor Schools in Southern California

    Science.gov (United States)

    Senger, Karen

    2012-01-01

    Purpose: The purposes of this study were to investigate and describe how elementary teachers in exited Program Improvement-Safe Harbor schools acquire student achievement data through assessments, the strategies and reflections utilized to make sense of the data to improve student achievement, ensure curriculum and instructional goals are aligned,…

  14. Thank goodness it's Friday: weekly pattern of workplace incivility.

    Science.gov (United States)

    Nicholson, Tahnee; Griffin, Barbara

    2017-01-01

    Recent research has shown day-level differences in an individual's experience of uncivil behavior; however, it is unknown if that experience follows a consistent weekly change pattern. This study extends incivility theory and research by applying latent growth curve (LGC) modeling to diary study data to understand day-to-day changes in incivility. The authors took a theory-driven approach, reviewing both mood and recovery theory that would support a decrease in incivility over the working week. Diary survey methodology was used, with a morning and evening survey completed on five consecutive workdays by 171 (73% of the 235 who initially volunteered, 95% of those who completed any surveys) employees in the legal industry. LGC analysis was used to identify patterns of experienced incivility, mood (both measured after work), and recovery (assessed the following morning). Regardless of job demands and gender, a weekly pattern was identified with the likelihood of experiencing incivility (coded as 0 = none, 1 = some) decreasing from Monday to Friday by .78 each day (p  .05), indicating invariance between individuals. This weekly pattern was not explained by changes in mood or recovery. Results emphasize the impact of contextual factors such as time on workplace incivility and the need to consider weekly rhythms of other behaviors that are likely to affect employee well-being and productivity. Although limited to one week of data per person, the findings are likely to be relevant to studies of other forms of interpersonal mistreatment, such as social undermining and interpersonal conflict.

  15. FITNESSGRAM® Friday: A Middle School Physical Activity and Fitness Intervention.

    Science.gov (United States)

    Murray, Tinker D; Eldridge, James; Silvius, Pete; Silvius, Erik; Squires, William G

    Texas Senate Bill 530 (2007) mandated fitness assessment as part of the annual K-8 Physical Education (PE) curricula, yet no studies have reported interventions designed to improve and quantify individual student passing rates or individual school performance. Students (Total 2008-2010 N=1484; 729 females, 755 males; mean age = 11.85 y; mean BMI = 22.69 or > 90%-tile, overweight) were evaluated on individual FITNESSGRAM® performances in a cross-sectional analysis of 6th graders comparing baseline scores (year 1) with outcomes of a physical activity intervention in years 2 and 3. Students participated in regular PE classes (including campus wellness center activities) with a once a week focus (FITNESSGRAM® Friday) on improving mile run scores and other assessment scores. Students significantly improved FITNESSGRAM® scores following the PE intervention to levels similar to state reported averages. On average, boys improved their pushups by 32.7%, trunk lift by 17.4% and mile run times by 29.5%. Averages for girls improved by 15.4% for pushups, 6.7% for truck lift, and by 38.6% for the mile run. The percentage of boys in our study achieving all six FITNESSGRAM® tests in the HFZ was 3% at baseline and 22% following intervention. The percentage of girls meeting the criteria for the HFZ on all six FITNESSGRAM® tests was 4.5% at baseline and 20% following intervention. This study provides a potential model for fitness success in other middle school PE interventions, in Texas and the nation.

  16. Females do not have more injury road accidents on Friday the 13th

    Science.gov (United States)

    Radun, Igor; Summala, Heikki

    2004-01-01

    Background This study reinvestigated the recent finding that females – but not males – die in traffic accidents on Friday the 13th more often than on other Fridays (Näyhä S: Traffic deaths and superstition on Friday the 13th. Am J Psychiatry 2002, 159: 2110–2111). The current study used matched setting and injury accident data base that is more numerous than fatality data. If such an effect would be caused by impaired psychic and psychomotor functioning due to more frequent anxiety among women, it should also appear in injury crashes. Methods We used the national Finnish road accident database for 1989–2002. To control seasonal variation, 21 Fridays the 13th were compared in a matched design to previous and following Fridays, excluding all holidays, on number of accidents, male/female responsibility for accidents, and the number of dead, injured and overall number of active participants (drivers, pedestrians and bicyclists) as a consequence of the accident. Results There were no significant differences in any examined aspect of road injury accidents among the three Fridays, either in females or males. Women were not overrepresented in crashes that occurred on Fridays 13th. Conclusion There is no consistent evidence for females having more road traffic crashes on Fridays the 13th, based on deaths or road accident statistics. However, this does not imply a non-existent effect of superstition related anxiety on accident risk as no exposure-to-risk data are available. People who are anxious of "Black Friday" may stay home, or at least avoid driving a car. PMID:15546493

  17. Friday Harbor Marina Expansion Study--San Juan Island, Washington: Final Detailed Project Report and Environmental Assessment.

    Science.gov (United States)

    1981-04-01

    INAS CTR i A ROK IWN ANT-7 I lIp , 0 OFNA TSPICA L TA PLA TYPICALL THROGHOU SECTION C-C SCALE l I ICUANFER ALL. EAPESED 11/2I.O SQUAAE COMPRESSIBLE EM YIA...Supervision and Administration 6,000 TOTAL FIRST COST $88,000 2. Tieup Facilities - Local Cost Bumpers BFM. 8,800 $1.75 15,400 Anchors Bolts 3/4" EA. 1,680

  18. Coastal Harbors Modeling Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Coastal Harbors Modeling Facility is used to aid in the planning of harbor development and in the design and layout of breakwaters, absorbers, etc.. The goal is...

  19. Water resources research program. Pollution of coastal waters off Chicago by sinking plumes from the Indiana Harbor Canal

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, W.; McCown, D.L.; Raphaelian, L.A.; Saunders, K.D.

    1977-12-01

    On March 2, 1977, during sinking-plume conditions, a portion of the water of the Indiana Harbor Canal (IHC) was injected with samarium and rhodamine-dye tags and a section of the IHC's surface was covered with simulated oily waste tagged with dysprosium. Water samples were taken downcurrent, over a 54-hr period, from a vessel and from the raw-water streams from the intakes at Chicago's South Water Filtration Plant (SWFP). Bottom currents and water temperatures were measured almost continuously at four Lake Michigan stations located between the IHC and the SWFP. Unequivocal evidence is presented for transport of the tagged IHC water and oily waste to the SWFP's intakes. Organic contaminants from the IHC were present in trace concentrations in the SWFP's raw water. A model for the transport and mixing of the entire IHC effluent, for the environmental conditions during the experiment, indicates a minimum dilution of 4 in the plume offshore of the SWFP and, for the assumed plume trajectory, values of 5 x 10/sup 2/ and 10/sup 5/ at the shore and crib intakes, respectively. A similar model applied to the experimental situation of tagged effluent showed reasonable agreement with measurements. Analysis of historical data indicates that the worst-case pollution event that might be experienced at the SWFP, assuming constant pollutant loading in the IHC, would be due to 24 hr of northwest wind followed by a 3.0-in. (7.6 cm), 24-hr rainfall that coincides with 3.0 x 10/sup 6/ m of total wind movement from the southerly quadrants.

  20. Friday Forum and the AICPA Core Competency Framework: Honing Students' Personal Competencies

    Science.gov (United States)

    Johnson, Grace F.

    2013-01-01

    This paper shares one learning technique for honing undergraduate students' personal competencies. The senior accounting capstone course at a small Midwestern private liberal college includes a weekly seminar series, called the Friday Forum, where students and practitioners meet to discuss a current professional accounting article. Since Spring…

  1. Commentary on "Friday Night Lights: A Town, A Team, and a Dream," by H. G. Bissinger.

    Science.gov (United States)

    Smith, Kenneth M.

    Through personal investigative reporting and compelling writing, H. G. Bissinger in "Friday Night Lights" (1991) explores the culture of high school football from a variety of perspectives including: students, parents, coaches, teachers, school boards, local politicians, community values regarding race, gender and education, regional…

  2. YouTube Fridays: Student Led Development of Engineering Estimate Problems

    Science.gov (United States)

    Liberatore, Matthew W.; Vestal, Charles R.; Herring, Andrew M.

    2012-01-01

    YouTube Fridays devotes a small fraction of class time to student-selected videos related to the course topic, e.g., thermodynamics. The students then write and solve a homework-like problem based on the events in the video. Three recent pilots involving over 300 students have developed a database of videos and questions that reinforce important…

  3. Acute coronary syndrome on Friday the 13th: a case for re-organising services?

    Science.gov (United States)

    Protty, Majd B; Jaafar, Mustafa; Hannoodee, Sahar; Freeman, Phillip

    2016-12-12

    Friday the 13th is described as an "unlucky" day that brings misfortune. There are few studies on the question, and none on its effect in cardiovascular patients. The recently misreported "weekend effect" has led to changes in the junior doctor contract in England, providing greater staffing levels on weekends. Should we make similar provisions for Friday the 13th? A retrospective analysis of a large database for patients admitted to hospitals in South Wales with an acute coronary syndrome (ACS) during 1999-2014. Mortality rates for 217 admission day number/name combinations and for Friday the 13th were compared in a Cox proportional hazards regression model. 56 062 ACS patients were identified. There were no significant differences in 13-year mortality between most admission dates (211 of 216) and Friday the 13th. However, a statistically significant reduction in mortality was identified for five dates: Thursday the 15th (HR, 0.77; 95% CI, 0.59-0.999), Wednesday the 18th (HR, 0.76; 95% CI, 0.58-0.99), Monday the 28th (HR, 0.76; 95% CI, 0.57-0.99), Monday the 30th (HR, 0.75; 95% CI, 0.57-0.99) and Tuesday the 31st (HR, 0.71; 95% CI, 0.51-0.99). On most days, there was no difference in the 13-year mortality rate for patients admitted with their first ACS from that for "unlucky" Friday the 13th. However, patients admitted on five day/number combinations were 20-30% more likely to survive at 13 years. These findings could be explained by subgroup analysis inflation of the type I error, although supernatural causes merit further investigation. Our findings should be taken into account in future junior doctor contract negotiations, and may provide a case for reduced staffing levels on these lucky days.

  4. Review: Lisa Mackenrodt, Swahili Spirit Possession and Islamic Healing in Contemporary Tanzania: The Jinn Fly on Friday (2011 Buchbesprechung: Lisa Mackenrodt, Swahili Spirit Possession and Islamic Healing in Contemporary Tanzania: The Jinn Fly on Friday (2011

    Directory of Open Access Journals (Sweden)

    Jigal Beez

    2013-01-01

    Full Text Available Review of the monograph:Lisa Mackenrodt, Swahili Spirit Possession and Islamic Healing in Contemporary Tanzania: The Jinn Fly on Friday, Hamburg: Verlag Dr. Kovač, 2011, ISBN 978-3-8300-5806-9, 216 pagesBesprechung der Monographie:Lisa Mackenrodt, Swahili Spirit Possession and Islamic Healing in Contemporary Tanzania: The Jinn Fly on Friday, Hamburg: Verlag Dr. Kovač, 2011, ISBN 978-3-8300-5806-9, 216 Seiten

  5. 76 FR 22899 - Federal Health IT Strategic Plan: 2011-2015 Open Comment Period Extended Until Friday, May 6

    Science.gov (United States)

    2011-04-25

    ..., May 6 AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION... extended through Friday, May 6 at 11:59 p.m. (Eastern). In order for your comments to be read and...

  6. Various administrative services and AIS applications unavailable on Friday 18th May 2007

    CERN Multimedia

    AIS Administrative Information Services

    2007-01-01

    Due to a major upgrade the Oracle HR application will not be available from Wednesday 16th May in the evening until Sunday 20th May. For that reason, various administrative services won't offer full service or will even be closed on Friday 18th May 2007. These services include: Users' Office Registration Office (building 55) Records Office (HR) ... and others (full list available on http://ais.cern.ch website) We thank you for your understanding. AIS Administrative Information Services ais.support@cern.ch

  7. Various administrative services and AIS applications unavailable on Friday 18th May 2007

    CERN Multimedia

    Administrative Information Services

    2007-01-01

    Due to a major upgrade Oracle HR application won't be available from Wednesday 16th May evening until Sunday 20th May. For that reason, various administrative services won't offer full service or will even be closed on Friday 18th May 2007. These services include: Users Office Registration Office (building 55) Records Office (HR) ...and others (full list available on http://ais.cern.ch website) We thank you for your understanding. AIS Administrative Information Services ais.support@cern.ch

  8. Integrating Sunday with Monday through Friday-Consistencies Between Biblical Principles and Management Theory

    OpenAIRE

    M. Kenneth Holt; Robert L. Holbrook

    2014-01-01

    Christianity often takes a back seat to secular pursuits rather than serving as the context from which these pursuits originate. In other words, we behave much differently Monday through Friday than we do on Sunday. Part of the problem is that we as Christians sometimes fail to see the inter connectedness of our work and our faith. We know what the Bible teaches about how we should conduct ourselves, and we know what management theorists have said about how we should conduct our business. Spe...

  9. Doing Business in the House of God: Negotiation Space between Worship and Economics on Friday Prayer

    Directory of Open Access Journals (Sweden)

    Muhammad Yafiz

    2016-10-01

    Full Text Available This article describes about  negotiation space between worship and economics on Friday prayer at Masjid Ulul Albab (MUA Medan. The main focus on this research is the appearance of pedagang kagetan (sudden traders on Friday pray laying down their merchandises such as worship equipments, Moslem clothing, meal, snack, mineral water, etc around the mosque. The findings of this articles is the phenomenon where there is  there is a change  function of the mosque becomes  a market. To understand the phenomenon, there are two questions appear:  what are the factors that contribute to the negotiations of worship and the economy and how the practice of economic progress. This paper explains that the factors pushing this situation because  there is  “blurring” between the room of worship and economic boundaries. Thus  there is dominance of economic  in the worship space. It happens because there is mutual need between merchants and pilgrims. It is done to meet the needs of the merchant family.

  10. Environmental Impact Research Program. Ecological Effects of Rubble-Mound Breakwater Construction and Channel Dredging at West Harbor, Ohio (Western Lake Erie).

    Science.gov (United States)

    1985-09-01

    would provide new habitat that would be rapidly colonized by periphyton and benthic macro- -, invertebrates (macrozoobenthos). Although the environmental...consumed by invertebrates which are eaten by fish and therefore may attract fish to the breakwater. However, a nuisance aspect of the Ciadophora is that...Harbor, Ohio (August 1981-1983) Taxa* Percent Porifera (Spongil a) 0.01 Cnidaria (Hydra) 0.30 Rhabdocoela 0.35 Tricladida 0.16 Nemertinea 0.14 Nematoda

  11. Floating-Harbor Syndrome

    OpenAIRE

    J Gordon Millichap

    1988-01-01

    Six unrelated children with a unique association of short stature, dysmorphic features, and speech delay are reported from the Harbor/Univ of California at Los Angeles Med Center, the Kennedy Memorial Hospital, Boston, the Beilinson Med Center, the District General Hospital, Stanford, England, and the Cedars-Sinai Med Cntr, Univ of California, LA.

  12. Port and Harbor Security

    Energy Technology Data Exchange (ETDEWEB)

    Saito, T; Guthmuller, H; DeWeert, M

    2004-12-15

    Port and Harbor Security is a daunting task to which optics and photonics offers significant solutions. We are pleased to report that the 2005 Defense and Security Symposium (DSS, Orlando, FL) will include reports on active and passive photonic systems operating from both airborne and subsurface platforms. In addition to imaging techniques, there are various photonic applications, such as total internal reflection fluorescence (TIRF), which can be used to ''sniff'' for traces of explosives or contaminants in marine. These non-imaging technologies are beyond the scope of this article, but will also be represented at DSS 2005. We encourage colleagues to join our technical group to help us to make our ports and harbors safer and more secure.

  13. Clean Water Act (Section 404) and Rivers and Harbors Act (Sections 9 and 10). Environmental Guidance Program Reference Book, Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    None

    1992-03-01

    This Reference Book contains a current copy of the Clean Water Act (Section 404) and the Rivers and Harbors Act (Sections 9 and 10) and those regulations that implement those sections of the statutes and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, IH-231 (FTS 896-2609 or Commercial 202/586-2609).

  14. Smolt Survival Workshop: Proceedings of a Workshop held at University of Washington Laboratory, Friday Harbor, Washington, February 1-3, 1989.

    Energy Technology Data Exchange (ETDEWEB)

    Dauble, Dennis D.; Neitzel, D.A.; Anderson, James J.

    1989-09-01

    A workshop was held at the University of Washington Laboratory to evaluate measures of juvenile salmon and steelhead survival and to recommend approaches for future studies in the Columbia River. Specific workshop goals included: review standards used to evaluate survival in previous studies and agree on standards for future studies, evaluate existing methods for determining survival, recommend types of survival studies that can be conducted with existing techniques, identify new approaches and facilities for improving survival estimates, and reach consensus on future directions for survival studies. 5 figs., 4 tabs.

  15. La formule des traces tordue d’après le Friday Morning Seminar

    CERN Document Server

    Labesse, Jean-Pierre

    2013-01-01

    La formule des traces pour un groupe réductif connexe arbitraire est due à James Arthur. Le cas tordu a fait l'objet du Friday Morning Seminar à l'Institute for Advanced Study de Princeton pendant l'année académique 1983-1984. Lors de ce séminaire, des exposés ont été présentés par Laurent Clozel, Jean-Pierre Labesse et Robert Langlands. Les notes de ces exposés, rédigées dans l'urgence, avaient besoin d'être revues et complétées. L'ambition des auteurs du présent ouvrage est de donner, en s'appuyant sur ces notes, une preuve complète pour la formule des traces tordue, dans sa version primitive i.e. sa forme non invariante. Ceci est la première étape du projet de l'équipe parisienne animée par Laurent Clozel et Jean-Loup Waldspurger, dont le but est de donner une preuve complète de la stabilisation de la formule des traces tordue, qui est l'outil fondamental utilisé par J. Arthur dans son livre à paraître sur l'endoscopie tordue pour le groupe linéaire avec application aux groupes ...

  16. Norovirus Infection in Harbor Porpoises.

    Science.gov (United States)

    de Graaf, Miranda; Bodewes, Rogier; van Elk, Cornelis E; van de Bildt, Marco; Getu, Sarah; Aron, Georgina I; Verjans, Georges M G M; Osterhaus, Albert D M E; van den Brand, Judith M A; Kuiken, Thijs; Koopmans, Marion P G

    2017-01-01

    A norovirus was detected in harbor porpoises, a previously unknown host for norovirus. This norovirus had low similarity to any known norovirus. Viral RNA was detected primarily in intestinal tissue, and specific serum antibodies were detected in 8 (24%) of 34 harbor porpoises from the North Sea.

  17. Norovirus Infection in Harbor Porpoises

    NARCIS (Netherlands)

    de Graaf, Miranda; Bodewes, Rogier|info:eu-repo/dai/nl/33230583X; van Elk, Cornelis E; van de Bildt, Marco; Getu, Sarah; Aron, Georgina I; Verjans, Georges M G M; Osterhaus, Albert D M E|info:eu-repo/dai/nl/074960172; van den Brand, Judith M A; Kuiken, Thijs; Koopmans, Marion P G

    A norovirus was detected in harbor porpoises, a previously unknown host for norovirus. This norovirus had low similarity to any known norovirus. Viral RNA was detected primarily in intestinal tissue, and specific serum antibodies were detected in 8 (24%) of 34 harbor porpoises from the North Sea.

  18. Genetics Home Reference: Floating-Harbor syndrome

    Science.gov (United States)

    ... Facebook Twitter Home Health Conditions Floating-Harbor syndrome Floating-Harbor syndrome Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Floating-Harbor syndrome is a disorder involving short stature, slowing ...

  19. Alaska Harbor Seal Glacial Surveys

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Floating glacial ice serves as a haul-out substrate for a significant number (10-15%) of Alaskan harbor seals, and thus surveying tidewater glacial fjords is an...

  20. Sediment toxicity in Savannah Harbor

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Savannah Harbor, located near the mouth of the Savannah River, Georgia and South Carolina, is impacted by industrial and municipal effluents. Contaminants released...

  1. Kaumalapau Harbor, Hawaii, Breakwater Repair

    Science.gov (United States)

    2012-05-01

    multiple degrees of freedom related to ship motion ( surge , sway , heave, roll, pitch, and yaw), and the associated position corrections needed by an...conditions. Local barge operators were using multi-ton ballast weights on the barges fore and aft to counter the harbor surge during loading operations...harbor basin to measure the breakwater’s effectiveness in damping waves that interfere with loading operations. These wave data will be compared to

  2. Field Verification Program (Aquatic Disposal). Use of Bioenergetics to Investigate the Impact of Dredged Material on Benthic Species: A Laboratory Study with Polychaetes and Black Rock Harbor Material.

    Science.gov (United States)

    1985-09-01

    Vol 179. McKinney, C.L., Jr. 1982. "Interrelationships Between Energy Metabolism, Growth Dynamics, and Reproduction During the Life Cycle of Mysidopsis...ANIMAL’S LIFE STAGE: JUVENILE SIZE: 1.40 +/- 0.33 MG DRY WI CONTROLS: 100 PERCENT REF FOOD: PRAWN FLA.E SUSPENSION ANIMAL SOURCE: SOUTH REFERENCE, LONG...dredged material. Evaluations were to be based on technology existing within the two agencies or developed during the six-year life of the program. 3. The

  3. 78 FR 43882 - Sunshine Act Meeting; Open Commission Meeting; Friday, July 19, 2013

    Science.gov (United States)

    2013-07-22

    ... the Delivery of Video Programming (MB Docket No. 12-203). SUMMARY: The Commission will consider a Fifteenth Report on the status of competition in the market for the delivery of video programming. 2 TITLE... captioning over the Internet from the FCC Live Web page at www.fcc.gov/live . For a fee this meeting can be...

  4. Prey capture by harbor porpoises

    DEFF Research Database (Denmark)

    Miller, Lee; Verfuss, Ursula

    2009-01-01

    their ultrasonic clicks as biosonar for orientation and detection of prey (mostly smaller pelagic and bottom dwelling fish), and for communication. For studying wild animals, hydrophone arrays and acoustic (time/depth) tags have been used. For studying captive animals, arrays and video techniques as well......  The harbor porpoise (Phocoena phocoena) is a small toothed whale living mostly in coastal waters.  There are large, but unknown, numbers in the inner Danish waters. Four are in captivity at Fjord & Bælt, Kerteminde, Denmark, one of which was born here in 2006. Harbor porpoises use...... as miniature acoustic-behavioral tags have been used. While searching for prey, captive harbor porpoises used clicks with intervals longer than 50 ms. After detecting the prey, the click interval stabilized at about 50 ms and then became progressively shorter while approaching the prey. During this time...

  5. Prey capture by harbor porpoises

    DEFF Research Database (Denmark)

    Miller, Lee

    2008-01-01

    (2007)] have been used.  For studying captive animals, arrays and video techniques [Verfuss et al. J.Exp.Biol. 208 (2005)] as well as miniature acoustic-behavioral tags [Deruiter et al. JASA 123 (2008)] have been used.  While searching for prey, harbor porpoises use clicks at long intervals (~50 ms...... The harbor porpoise (Phocoena phocoena) is a small toothed whale living mostly in coastal waters.  There are large, but unknown, numbers in the inner Danish waters.  Four are in captivity at Fjord & Bælt, Kerteminde, Denmark, one of which was born here in 2006.  Harbor porpoises use...... their ultrasonic clicks as biosonar for orientation and detection of prey (mostly smaller pelagic and bottom dwelling fish), and for communication.  For studying wild animals, hydrophone arrays [Villadsgaard et al. J.Exp.Biol. 210 (2007)] and acoustic (time/depth) tags [Akamatsu et al. Deep Sea Research II 54...

  6. Summary of Pacific harbor seal, Phoca vitulina richardsi, surveys in California, 1982 to 1995

    OpenAIRE

    Fluharty, Marilyn J.

    1999-01-01

    The California Department of Fish and Game (CDFG) initiated an annual Pacific harbor seal, Phoca vitulina richardsi, census along the California coast in 1981 as part of an assessment program conducted cooperatively with National Marine Fisheries Service. Surveys were conducted during the harbor seal molting season and census data were used as an index of abundance to detect changes in population abundance or distribution. Because not all harbor seals are hauled-out at the time of the s...

  7. Prostate Cancer Research Training Program

    Science.gov (United States)

    2014-05-01

    specific interest in minimally invasive procedures, new techniques, and outcomes. Dr. Brown initiated many of the laparoscopic and robotic programs at...These include, but are not limited to, the following: Friday and Saturday Night Concert Series – Free musical concerts held each Friday and...Thursday Night Concerts in Coralville – These musical concerts, held in Morrison Park in the adjacent town of Coralville, IA, are also free and

  8. Reduced service of the “IT Service Desk” (Computing Helpdesk) on the after noon of Friday 8 October 2010

    CERN Multimedia

    IT Department

    2010-01-01

    Please note that due to relocation, the “IT Service Desk” will be operating a reduced service on Friday 8th October from 12-30. In particular, the telephone line 78888 will not be available and users will be invited to submit their requests by e-mail (Computing.Helpdesk@cern.ch). E-mail requests will be treated as normal, but some delays are possible. In the event of urgent problems you may call the IT Manager on Duty on 163013. We also take this opportunity to remind you about the “IT Service Status Board” where all computing incidents and scheduled interventions are updated online. Please see: http://cern.ch/it-servicestatus. Normal service will be resumed at 8-30 a.m on Monday 11 October. Thank you in advance for your understanding. The CERN “User Support” Team (IT-UDS-HUS)

  9. Surgidero de Batabanó Harbor, Cuba

    NARCIS (Netherlands)

    Hopmans, R.; Van Kessel, L.; Lendering, K.; Oud, M.; Tromp, R.

    2011-01-01

    The harbor of Surgidero de Batabano is a harbor that lies in the Gulf of Batabano in the South-Western part of Cuba. It serves as a connection between the main land of Cuba and the islands 'Isla de la Juventud' and Cayo Largo. The Batabano harbor suffers from sediment accretion. The accretion of

  10. The Floating-Harbor syndrome.

    Science.gov (United States)

    Majewski, F; Lenard, H G

    1991-02-01

    We describe the seventh patient with the Floating-Harbor syndrome. Similar to previous cases in the literature this girl presented with proportionate intrauterine and postnatal growth retardation, normocephaly, triangular face with bulbous nose, long eyelashes, short upper lip, small vermilion border of upper lip, dorsally rotated ears, deep nuchal hair line, hirsutism, and clinodactyly of little fingers. She exhibited mental retardation and retarded speech development. Clinical symptoms and differential diagnosis of this rare syndrome are briefly discussed.

  11. Tributyltin contamination and imposex in Alaska harbors.

    Science.gov (United States)

    Tallmon, David A

    2012-02-01

    We quantified imposex in file dogwinkles (Nucella lima) and tributyltin (TBT) contamination in bay mussels (Mytilus trossulus) from 10 harbors and nearby control sites throughout Alaska. We found evidence of TBT contamination in mussels from four harbors (29-54 ng TBT/g wet tissue wt). Two of these harbors now show reduced TBT contamination relative to levels found in 1987. We were able to find and collect dogwinkles from seven sites. Of these, all three dogwinkle samples from harbor sites exhibited imposex, with 36%-87.5% females affected per site. In total, six of the 10 harbors had some evidence of TBT contamination.

  12. Butyltin Concentrations in Selected US Harbor Systems. A Baseline Assessment.

    Science.gov (United States)

    1987-04-01

    ecological resources exist in both Pearl Harbo , and Honolulu Harbor. .0 Pearl Harbor exhibits the characteristically high biological complexity and...Naval Shipyard. Bremerton, Washington; Pearl Harbor and Honolulu Harbor/Kewalo Basin. Hawaii; Mayport-St. John’s River Complex. Florida; Charleston...18 Bremerton (Sinclair Inlet) Washington ....................................... 20 Pearl Harbor. Honolulu Harbor and

  13. CRSMP Potential Harbor Borrow Sites 2012

    Data.gov (United States)

    California Department of Resources — Harbor locations as identified originally in the California Shoreline Database compiled by Noble Consultants (Jon Moore) for California Department of Boating and...

  14. 33 CFR 100.109 - Winter Harbor Lobster Boat Race, Winter Harbor, ME.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Winter Harbor Lobster Boat Race, Winter Harbor, ME. 100.109 Section 100.109 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Lobster Boat Race, Winter Harbor, ME. (a) Regulated area. The regulated area includes all waters of Winter...

  15. 78 FR 38577 - Special Local Regulations; Red Bull Flugtag National Harbor Event, Potomac River; National Harbor...

    Science.gov (United States)

    2013-06-27

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Red Bull Flugtag National...; Red Bull Flugtag National Harbor Event, Potomac River; National Harbor Access Channel, MD'' in the... safety of life on navigable waters of the United States during the Red Bull Flugtag National Harbor event...

  16. 78 FR 18274 - Special Local Regulations; Red Bull Flugtag National Harbor Event, Potomac River; National Harbor...

    Science.gov (United States)

    2013-03-26

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Red Bull Flugtag National... during the ``Red Bull Flugtag National Harbor event,'' to be held on the waters of the Potomac River on... of National Harbor, Maryland, is sponsoring the Red Bull Flugtag National Harbor event, a competition...

  17. 33 CFR 117.549 - Cambridge Harbor.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cambridge Harbor. 117.549 Section... DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Maryland § 117.549 Cambridge Harbor. The draw of the S342 bridge, mile 0.1 at Cambridge, shall open on signal from 6 a.m. to 8 p.m.; except that, from 12...

  18. Floating-Harbor syndrome: case report.

    Science.gov (United States)

    Genc, G; Sarac, A; Erkek Atay, N; Kulali, F

    2008-04-01

    Floating-Harbor syndrome is a rare disorder which is clinically characterized by short stature, retarded speech development, delayed bone ages, triangular face, bulbous nose and thin lips. We described two cases with Floating-Harbor syndrome and briefly reviewed the relevant literature.

  19. Development of Targeted Molecular Therapy for Cancers Harboring BAP1 Mutations

    Science.gov (United States)

    2016-10-01

    AWARD NUMBER: W81XWH-15-1-0578 TITLE: Development of Targeted Molecular Therapy for Cancers Harboring BAP1 Mutations PRINCIPAL INVESTIGATOR: Dr...CONTRACT NUMBER Development of Targeted Molecular Therapy for Cancers Harboring BAP1 Mutations 5b. GRANT NUMBER W81XWH-15-1-0578 5c. PROGRAM... mutations could provide a powerful new strategy for treating these cancers. Unfortunately, there are several obstacles to developing such therapies

  20. Chignik small boat harbor planning aid report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Unless additional salmon use data would indicate otherwise, harbor site 3 is considered the environmentally preferred alternative for construction of a small...

  1. Sonorities of a Good Friday Procession rewritten by Silvio Ferraz in Itinerário da Passagem: Verônica Nadir

    Directory of Open Access Journals (Sweden)

    Tadeu Moraes Taffarello

    2017-04-01

    Full Text Available In 1978, Brazilian composer Silvio Ferraz had been present at a Good Friday procession in Prados, Minas Gerais. He was deeply moved by its sonority and symbolism. Thirty years later in 2008 Ferraz composed the piece Itinerário da Passagem: Veronica Nadir (“Itinerary of the Passage: Veronica Nadir” for cello solo, string orchestra and percussion. This article contextualizes the piece, analyzes its harmony, discusses its sonorities and reveals its arc form based on density flux and harmonic rarefactions.

  2. New Harbor in Kangerlussuaq, Western Greenland

    DEFF Research Database (Denmark)

    Stenstad, Jaran Gjerlandj; Eppeland, Kjetil Grødal; Ingeman-Nielsen, Thomas

    2015-01-01

    transported by rivers from the inland ice to the inner parts of the fjord. These sediment layers reduce the water depth and prevent container- and cruiseships to dock, imposing large additional maintenance costs, and inefficient operability. Through engineering geological field and lab investigations......The international airport of Greenland is located in Kangerlussuaq, making it an important connection point for tourists and transportation of goods. However, the existing harbor in Kangerlussuaq experiences major challenges in the form of extensive sedimentation of glaciofluvial sediments......, a possible new harbor location around 10 km further out the fjord near Hancock Pynt, has been investigated. The onshore area was found to be highly suitable for a harbor support area, where a sub-base thickness of 1.8 m with gravel cover-layer was found adequate for the calculated design loads. Existing...

  3. Ocular abnormalities in Floating-Harbor syndrome.

    Science.gov (United States)

    Asseidat, Ibrahim; Kaufman, Lawrence M

    2009-04-01

    We present the first case report of a comprehensive eye examination in a patient with Floating-Harbor syndrome. Ocular findings were limited to partially accommodative, acquired esotropia, and unusual eyelashes. A variety of other ocular features have been previously reported in the nonophthalmic medical literature and are herein reviewed.

  4. 77 FR 42640 - Safety Zone; Can-Am Festival Fireworks, Black River Bay, Sackets Harbor, NY

    Science.gov (United States)

    2012-07-20

    .... Wright, Program Manager, Docket Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: Table of... Act (APA) (5 U.S.C. 553(b)). This provision authorizes an agency to issue a rule without prior notice... Part 165 Harbors, Marine safety, Navigation (water), Reporting and recordkeeping requirements, Security...

  5. USGS Lake Erie East Harbor bottom trawl data series, 1961-2011

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The USGS Lake Erie Biological Station’s East Harbor sampling program began in 1961 with the commissioning of the research vessel Musky II. It is the longest known...

  6. Akutan, Alaska bottomfish harbor study feasibility stage: Planning aid report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Six alternatives are presently being studied by the Corps of Engineers, in conjunction with facilitating construction of a bottomfish harbor at Akutan Harbor located...

  7. Aerial Survey Units for Harbor Seals in Coastal Alaska

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Aerial surveys of coastal Alaska are the primary method for estimating abundance of harbor seals. A particular challenge associated with aerial surveys of harbor...

  8. 32 CFR 765.6 - Regulations for Pearl Harbor, Hawaii.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Regulations for Pearl Harbor, Hawaii. 765.6... RULES RULES APPLICABLE TO THE PUBLIC § 765.6 Regulations for Pearl Harbor, Hawaii. The Commander, U.S. Naval Base, Pearl Harbor, Hawaii, is responsible for prescribing and enforcing such rules and...

  9. Floating-Harbor syndrome and celiac disease.

    Science.gov (United States)

    Chudley, A E; Moroz, S P

    1991-03-15

    We report on a 17-year-old young woman with a speech impediment, developmental delay, short stature, and facial anomalies consistent with the Floating-Harbor syndrome (FHS). In addition, she has clinical and histological evidence of celiac disease, which was observed in 1 of the 6 previously reported cases of FHS, suggesting a possible association between the 2 conditions or pleiotropism of a presumed autosomal recessive disorder.

  10. Changing phenotype in Floating-Harbor syndrome.

    Science.gov (United States)

    Hersh, J H; Groom, K R; Yen, F F; Verdi, G D

    1998-02-26

    We report on a girl with Floating-Harbor syndrome, trigonocephaly due to metopic suture synostosis, preauricular pit, hypoplastic thumb, subluxated radial head, and Sprengel deformity. A review suggests that trigonocephaly may be an important craniofacial manifestation in this syndrome that is recognizable in infancy. With time, this finding appears to become less noticeable, and the face develops a triangular shape, accentuated by a broad and bulbous nose.

  11. A Guide for Marina and Harbor Managers

    Science.gov (United States)

    1991-03-01

    and provided feedback to the questionaire . Appendix C shows the names and addresses of the facilities that responded. Three out of these eight...Title 14 5L, California Harbors and Navigation Code 81, Recreational Boat and Sport Fishing Enhancement 321, Act of 1984 Private Planning and...submission of information and 6 limitations. 32L. Recreational Boating and Sport Fishing Enhancement Act of 1984, (Wallop-Breaux Act) Gives an apportionment to

  12. Characteristics and management of Enterobacteriaceae harboring ...

    African Journals Online (AJOL)

    Cite as: Pang F, Jia X-q, Song Z-z, Li Yh, Wang B, Zhao Q-g, Wang C-x, Zhang Y, Wang L-x. Characteristics and management of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemase in a tertiary hospital. Afri Health Sci. 2016;16(1): 153-161. http://dx.doi.org/10.4314/ahs.v16i1.21. * Corresponding authors:.

  13. "Teaching Old Dogs New Tricks": The ELDERSCHOLAR Program.

    Science.gov (United States)

    Banziger, George

    The Elderscholar program was initiated in Marietta, Ohio, in the spring of 1988 as a special noncredit program for learners over the age of 55. Ten courses (two at each of five time slots) were offered for 50-minute periods on six consecutive Fridays. Courses were offered in creative writing, religions of the world, modern literature,…

  14. Biodiversity of Freshwater and Estuarine Communities in Lower Pearl Harbor, Oahu, Hawaii with Observations on Introduced Species: Summary from Fieldwork Conducted in 1997-1998 (NODC Accession 0001114)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Pearl Harbor Biodiversity Project was funded by the Department of Defense Legacy Program, through the U. S. Navy. The project was performed in two phases. Phase...

  15. Biodiversity of freshwater and estuarine communities in lower Pearl Harbor, Oahu, Hawaii with observations on introduced species: summary from fieldwork conducted in 1997 - 1998 (NODC Accession 0001114)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Pearl Harbor Biodiversity Project was funded by the Department of Defense Legacy Program, through the U. S. Navy. The project was performed in two phases. The...

  16. Floating-Harbor syndrome. A neuropsychological approach.

    Science.gov (United States)

    Davalos, I P; Figuera, L E; Bobadilla, L; Martinez-Martinez, R; Matute, E; Partida, M G; Bañuelos, L A; Ramirez-Dueñas, M L

    1996-01-01

    We describe a six year old Mexican girl whose clinical picture (short stature with delayed bone age, language difficulties and triangular face with prominent nose) was compatible with the diagnosis of Floating-Harbor Syndrome (FHS). A neuropsychological evaluation disclosed a mild mental retardation, a constructive apraxia, a comprehensive and expressive language impairment. The analysis of the present case and sixteen patients previously described establishes that the FHS is mainly characterized by proportionate short stature with significantly delayed bone age, delayed expressive language and peculiar face.

  17. 77 FR 50916 - Safety Zone; Boston Harbor's Rock Removal Project, Boston Inner Harbor, Boston, MA

    Science.gov (United States)

    2012-08-23

    ...) Zone for the drilling, blasting, and dredging operation on the navigable waters of Boston Inner Harbor... navigable waters during the drilling, blasting and dredging operations in support of the U.S. Army Corps of... vicinity of the drilling, dredging and blasting operations being conducted. For the safety concerns noted...

  18. 33 CFR 207.480 - Lake Huron, Mich.; Harbor of refuge, Harbor Beach; use and navigation.

    Science.gov (United States)

    2010-07-01

    ...) Passenger boats will, in general, have the preference as to location and attention by the officer in charge... floating property making fast to the breakwater must at once place such fenders between themselves and the... piece of floating property made fast to the breakwater, or anchored in the harbor, must keep outboard...

  19. DYNAMICS OF LOCAL ISLAM: FATWA OF MUHAMMAD BASIUNI IMRAN, THE GRAND IMAM OF SAMBAS, ON THE FRIDAY PRAYER ATTENDED BY FEWER THAN FORTY PEOPLE

    Directory of Open Access Journals (Sweden)

    Hamka Siregar

    2013-12-01

    Full Text Available This article is an analitical work based on local Islam dynamic of Sambas society in the era of Sambas Sultanate. The work attempts to promote intellectual heritages such as the book of Cahaya Suluh, which could at least give us an idea that in a process of setting certain rules or istinbat, there is a need for flexibility. As can be observed from the whole argument built in this book, the process is completely flexible, not merely following one school of thought. As indicated in this paper, especially in the discussion of his thought, Muhammad Basiuni Imran used various references for his propositions. Although he was an advocate of the school of Syafi’i, he was still open to the other schools of thought. As a matter of fact, in the case of Friday prayer, his position was different from the school of thought he supported. He took that position because he considered the socio cultural conditions of Sambas at the time. Intellectual spirit shown by the Grand Imam of Sambas should continue to be emulated and expanded. It is a way to avoid the ‘blind’ taqlid against a certain school of thought, as such attitude can narrow human intelligence and reasoning which will eventually lead to collision with local reality that sometimes contains values that do not contradict with religion. In addition, the approach to the interpretation of law should look at its socio-cultural and historical background as this will keep the law strong and sustainable. In this way, Islam will be easily accepted without having to impose foreign culture on local people. Keywords: Dynamic, Islam, Sambas, Grand Imam, Muhammad Basuni Imran

  20. 33 CFR 110.238 - Apra Harbor, Guam.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. 110.238 Section 110.238 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.238 Apra Harbor, Guam. (a) The anchorage grounds (Datum: WGS...

  1. 77 FR 22489 - Special Anchorage Regulations, Newport Bay Harbor, CA

    Science.gov (United States)

    2012-04-16

    ... amendment adjusts the lines to fit the current layout of moorings in Newport Harbor. Small craft are not... aft moorings for recreational and small craft of such size and alignment as permitted by the harbor... material received from the public, as well as documents mentioned in this preamble as being available in...

  2. 33 CFR 165.1309 - Eagle Harbor, Bainbridge Island, WA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Eagle Harbor, Bainbridge Island, WA. 165.1309 Section 165.1309 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Eagle Harbor, Bainbridge Island, WA. (a) Regulated area. A regulated navigation area is established on...

  3. 33 CFR 80.1470 - Kawaihae Harbor, Hawaii, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Kawaihae Harbor, Hawaii, HI. 80.1470 Section 80.1470 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1470 Kawaihae Harbor, Hawaii, HI...

  4. 33 CFR 80.1480 - Hilo Harbor, Hawaii, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hilo Harbor, Hawaii, HI. 80.1480 Section 80.1480 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1480 Hilo Harbor, Hawaii, HI. A line drawn...

  5. 33 CFR 80.1450 - Nawiliwili Harbor, Kauai, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Nawiliwili Harbor, Kauai, HI. 80.1450 Section 80.1450 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1450 Nawiliwili Harbor, Kauai, HI...

  6. 78 FR 29089 - Safety Zones; Hawaiian Island Commercial Harbors, HI

    Science.gov (United States)

    2013-05-17

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zones; Hawaiian Island Commercial Harbors, HI... Safety Zones; Hawaiian Islands Commercial Harbors; HI. (a) Location. The following areas are safety zones...

  7. 78 FR 63381 - Safety Zones; Hawaiian Island Commercial Harbors, HI

    Science.gov (United States)

    2013-10-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zones; Hawaiian Island Commercial Harbors, HI.... 14-1414 Safety Zones; Hawaiian Islands Commercial Harbors; HI. (a) Location. The following commercial...

  8. 33 CFR 80.1460 - Kahului Harbor, Maui, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Kahului Harbor, Maui, HI. 80.1460 Section 80.1460 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1460 Kahului Harbor, Maui, HI. A line drawn...

  9. Association of holidays, full moon, Friday the 13th, day of week, time of day, day of week, and time of year on case distribution in an urban referral small animal emergency clinic.

    Science.gov (United States)

    Drobatz, Kenneth J; Syring, Rebecca; Reineke, Erica; Meadows, Cheyney

    2009-10-01

    To interrogate the association of variables: day of week, time of day, day of the year (major holidays, Friday the 13th, and the full moon), and month of year with the caseload of an urban academic emergency service. Retrospective study. Urban small animal teaching hospital emergency clinic. Cats and dogs that were presented to the emergency clinic. None. The hospital computer database was searched for all visits to the Emergency Service of the Mathew J. Ryan Veterinary Hospital of the University of Pennsylvania from January 1, 1987 through December 31, 2002. Variables included in the electronic data were date of admission, time of day of admission, species (dog or cat), hospital service the case was transferred to for ongoing care and whether the case was discharged directly from the emergency service. The association of caseload with day of week, time of day, day of the year (major holidays, Friday the 13th, and the full moon), and month of year was described and statistically evaluated. Saturdays and Sundays were the busiest days of the week and significantly increased caseload was noted for the majority of holidays (except Easter Day and Thanksgiving Day) with Memorial Day being the busiest. Midweek evenings as well as Saturday and Sunday afternoons were the busiest periods of the day. There was no association with caseload and Halloween, the full moon, or Friday the 13th. The busiest times were midweek evenings, Saturday and Sunday afternoons, and most major holidays.

  10. AKSI KOLEKTIF DALAM BERSEPEDA: Studi Banding Atas Sego Segawe (Sepeda Kanggo Sekolah lan Nyambut Gawe dan JLFR (Jogja Last Friday Ride di Kota Yogyakarta

    Directory of Open Access Journals (Sweden)

    Mohamad Jamal Thoriq

    2016-09-01

    Full Text Available Munculnya berbagai gerakan berbasis lingkungan merupakan respon atas krisis lingkungan hidup di Kota Yogyakarta. Atas inisiasi Mantan Walikota Yogyakarta, Sego Segawe (Sepeda nggo Sekolah lan Nyambut Gawe dihadirkan pada 2008 sebagai gerakan bersepeda. Kultur bersepeda di Kota Yogyakarta yang sedang kondusif dimanfaatkan para pesepeda untuk melahirkan kegiatan bersepeda bernama JLFR (Jogja Last Friday Ride pada 2010. Secara eksplisit, keduanya memiliki tujuan yang sama, yaitu menumbuhkan kesadaran warga untuk kembali menggunakan sepeda sebagai transportasi hijau. Meski demikian, terdapat perbedaan pada cara Sego Segawe maupun JLFR dalam menggalang aksi secara kolektif. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana perbandingan pola sosialisasi Sego Segawe dan JLFR dalam menggalang aksi secara kolektif dan mengetahui faktor-faktor yang mendukung dan menghambat keberlangsungan Sego Segawe dan JLFR. Hasil penelitian ini diharapkan mampu menjadi sarana informasi kepada publik dalam kampanye penggunaan sepeda sebagai transportasi hijau. Penelitian ini berpijak pada teori Aksi Kolektif Alberto Melucci (1996 & 1989, konsep Sosialisasi dari Rush dan Althof (2007, dan 5 Mekanisme Sosialisasi menurut Damsar (2010. Penelitian ini dilaksanakan dalam waktu lebih kurang 3 bulan, yaitu mulai akhir Agustus sampai dengan awal November 2014. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif komparatif. Tehnik sampling yang digunakan adalah purposive sampling. Informan dipilih yang memenuhi syarat penelitian, yaitu; 1 informan dari stakeholder Kota Yogyakarta, 5 informan dari Sego Segawe, 5 informan dari JLFR. Metode pengumpulan data dilakukan dengan cara observasi, wawancara dan dokumentasi. Tehnik analisis data dilakukan dengan cara reduksi data, display data dan terakhir ditarik kesimpulan. Hasil penelitian menunjukkan perbedaan antara Sego Segawe dan JLFR pada pola sosialisasi yang dibagi menjadi 5 mekanisme sosialisasi

  11. 77 FR 24766 - Call for Proposals for a Micro Support Program on International Conflict Resolution and...

    Science.gov (United States)

    2012-04-25

    ... funding, and provide financial and report management oversight. Deadline: Friday, May 11, 2012 at 3 p.m... PEACE Call for Proposals for a Micro Support Program on International Conflict Resolution and... Support Program on International Conflict Resolution and Peacebuilding. The United States Institute of...

  12. 75 FR 78798 - Airport Improvement Program: Proposed Changes to Benefit Cost Analysis (BCA) Threshold

    Science.gov (United States)

    2010-12-16

    ... Federal Aviation Administration Airport Improvement Program: Proposed Changes to Benefit Cost Analysis... requiring benefit cost analyses (BCA) for capacity projects when applying for Airport Improvement Program... Friday, except Federal holidays. Privacy: We will post all comments we receive, without change, to http...

  13. Sediment quality assessment studies in Boston Harbor, Massachusetts

    Energy Technology Data Exchange (ETDEWEB)

    Carr, R.S.; Chapman, D.C.; Biedenbach, J.M. [National Biological Service, Corpus Christi, TX (United States). Texas Gulf Coast Field Station; Long, E.R. [NOAA, Seattle, WA (United States); Thursby, G. [Science Applications International Corp., Narragansett, RI (United States); MacDonald, D.D. [MacDonald Environmental Sciences Ltd., Ladysmith, British Columbia (Canada)

    1995-12-31

    As part of NOAA`s National Status and Trends program, a bioeffects assessment study was conducted in the vicinity of Boston Harbor, Massachusetts. Surficial sediment samples were collected at 55 sites and subsamples were tested for toxicity using (1) the 10-day whole sediment test with Ampelisca abdita, (2) the sea urchin (Arbacia punctulata) fertilization and embryological development assays with sediment pore water, and (3) Microtox{trademark} assay with organic sediment extracts. Eleven percent of the samples were significantly toxic in the amphipod test, only 4% were toxic in the sea urchin fertilization test whereas all of the samples were highly toxic in the sea urchin embryological development assay; the Microtox assay determined 56% of the organic sediment extracts to be significantly toxic. Sediment chemical analyses for metals, AVS/SEM, PAHs, PCBs, and pesticides were performed on 30 of the 55 samples. Twenty-seven of the 30 samples exceeded at least one probable effects level (PEL) value. For the 20 samples that exceeded 5 or more PELS, the concordance between the predicted and observed toxicity was 20% for the amphipod test, 60% for the Microtox test, and 100% for the sea urchin embryological development assay. There were no significant correlations among the different toxicity tests or between the tests and the contaminant concentrations in the bulk sediment. Possible explanations for the apparent lack of correlation between the sediment chemistry and the toxicity tests will be discussed.

  14. Pearl Harbor, Hawaii Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Pearl Harbor, Hawaii Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST) model....

  15. 78 FR 37456 - Safety Zone; Milwaukee Harbor, Milwaukee, WI

    Science.gov (United States)

    2013-06-21

    ... have questions on this notice, call or email MST1 Joseph McCollum, Prevention Department, Coast Guard... Harbor, Milwaukee, WI, at the following times for the following events: (1) Polish Fest fireworks display...

  16. Pearl Harbor National Wildlife Refuge: Comprehensive Conservation Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Comprehensive Conservation Plan (CCP) was written to guide management on Pearl Harbor National Wildlife Refuge for the next 15 years. This plan outlines the...

  17. Pearl Harbor, Hawaii 1 arc-second DEM

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 1/3-second Pearl Harbor Hawaii Elevation Grid provides bathymetric data in ASCII raster format of 1/3-second resolution in geographic coordinates. This grid is...

  18. Apra Harbor, Guam Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Apra Harbor, Guam Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST) model. MOST...

  19. Boston Harbor and approaches samples (WILLETT72 shapefile

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Boston Harbor (and its approaches) is a glacially carved, tidally dominated estuary in western Massachusetts Bay. Characterized by low river discharge and...

  20. Characterizing freshwater and nutrient fluxes to West Falmouth Harbor, Massachusetts

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — These data present oceanographic and water-quality observations made at 4 locations in West Falmouth Harbor and 3 in Buzzards Bay, Massachusetts. While both Buzzards...

  1. Environmental Assessment for Boston Harbor Maintenance Dredging, Boston, Massachusetts.

    Science.gov (United States)

    1981-12-01

    into the harbor, but the sources have never been documented. It is not unusual for the swimming beaches to be closed following a storm of moderate...sand lance involve either swimming in schools or burrowing In suitable substrate. Impacts to their natural schooling movements are iikely to be short...Edison (December 1976 - May 1977) Appendix B Boston Inner Harbor Species List Scientific Name Comm~on Nam~e CNIDARIA (Hycdroids, Anemones, Jellyfish

  2. Assessment of Modifications for Improving Navigation at Hilo Harbor, Hawaii

    Science.gov (United States)

    2016-06-01

    proposed modifications, (5) develop hydrodynamic conditions for the ship simulator study, and (6) document study results by a technical report. The...breakwater, and (f) developing hydrodynamic conditions for the ship simulator study. 1.3 Study area Hilo Harbor is a deep-draft port located in Hilo Bay...on the Island of Hawaii at the mouth of two rivers, the Wailuku River and the smaller Wailoa River. There is also a small- boat harbor in Radio Bay

  3. [Floating-Harbor syndrome in a girl with somatic asymmetry].

    Science.gov (United States)

    Midro, A T; Rogowska, M; Hubert, E; Hassman-Poznańska, E; Popko, J

    1995-09-01

    Floating-Harbor syndrome, a genetic disorder of unknown etiology, was diagnosed in a 9-year-old girl with delayed morphologic, bone and dental age, lateral asymmetry of the body, triangular face, hypotelorism, broad palpepral fissures, long eye-lashes, narrow jaw, retrogenia, a defect of phonemic audition and speech delay with poor articulation. Similarity between Floating-Harbor syndrome and Silver-Russel syndrome is discussed.

  4. Sun Coke heat recovery coke technology at Indiana Harbor

    Energy Technology Data Exchange (ETDEWEB)

    Walker, D.N. [Sun Coke Company (USA). Operations

    1999-12-01

    Sun Coke heat recovery coke technology was fully established for the first time at Indiana Harbor Coke Company, East Chicago, Indiana (USA). The plant supplies continuous heat to waste heat boilers which provide steam for a 94 MW turbine generator whilst producing 1,350,00 NT per year of metallurgical coke. The paper briefly describes the development of the technology and discusses specific design aspects of the Indiana Harbor plant. 3 refs., 2 figs., 2 tabs.

  5. Evaluation of Breakwaters and Sedimentation at Dana Point Harbor, CA

    Science.gov (United States)

    2011-05-01

    manmade and is protected from ocean waves by a pair of riprapped breakwaters constructed in the late 1960s. The breakwaters, consist of a long shore...Fugro West 2010). Bathymetric data were also collected in the marina basins, harbor entrance and nearshore areas outside the harbor. Two ADCPs were...tidal range (mean higher high water - mean lower low water) is 1.67 m. Wind data were available from NOAA coastal stations at Los Angeles Pier S

  6. Satellite Monitoring of Boston Harbor Water Quality: Initial Investigations

    Science.gov (United States)

    Sheldon, P.; Chen, R. F.; Schaaf, C.; Pahlevan, N.; Lee, Z.

    2016-02-01

    The transformation of Boston Harbor from the "dirtiest in America" to a National Park Area is one of the most remarkable estuarine recoveries in the world. A long-term water quality dataset from 1991 to present exists in Boston Harbor due to a $3. 8 billion lawsuit requiring the harbor clean-up. This project uses discrete water sampling and underway transects with a towed vehicle coordinated with Landsat 7 and Landsat 8 to create surface maps of chlorophyll a (Chl a), dissolved organic matter (CDOM and DOC), total suspended solids (TSS), diffuse attenuation coefficient (Kd_490), and photic depth in Boston Harbor. In addition, 3 buoys have been designed, constructed, and deployed in Boston Harbor that measure Chl a and CDOM fluorescence, optical backscatter, salinity, temperature, and meteorological parameters. We are initially using summer and fall of 2015 to develop atmospheric corrections for conditions in Boston Harbor and develop algorithms for Landsat 8 data to estimate in water photic depth, TSS, Chl a, Kd_490, and CDOM. We will report on initial buoy and cruise data and show 2015 Landsat-derived distributions of water quality parameters. It is our hope that once algorithms for present Landsat imagery can be developed, historical maps of water quality can be constructed using in water data back to 1991.

  7. Environmental evaluations for deepening of Richmond Harbor and Santa Fe Channels

    Energy Technology Data Exchange (ETDEWEB)

    Brown, B.; Kohn, N.P.; Crecelius, E.A.; Ward, J.A.; Bjornstad, B.N. (Battelle/Marine Sciences Lab., Sequim, WA (USA))

    1990-09-01

    Richland, California is an important commercial port in San Francisco Bay. The San Francisco District of the US Army Corps of Engineers (USACE) plans to increase the depth of Richmond Harbor and Santa Fe Channels to -38 feet Mean Lower Low Water (MLLW) to accommodate deep-draft commercial vessels. The total volume of dredged material is expected to be approximately 1.4 million cubic yards. The options for disposal of the dredged material are aquatic disposal and upland disposal. The purpose of this study was to develop a database on chemical compounds in the dredged material to assist with determination of disposal methods and the need for additional testing. This purpose was accomplished through an extensive field sampling program followed by chemical analysis of samples. Field sampling involved collection of core samples from Sante Fe and Richmond Harbor Channels. Cores were shipped to Battelle/Marine Sciences Laboratory, where they were subsampled for chemical analysis and/or archived by freezing. All sediment and water samples were analyzed for priority pollutants, including metals, organotins, base/neutral semivolatile organic compounds, chlorinated pesticides and PCBs, herbicide acids, and acidic phenols. Sediment samples were also analyzed for oil and grease and total organic carbon. Organophosphorus pesticides and dioxins and furans were measured in selected sediment samples from Richland Harbor Channel and from both sediment and water samples from Santa Fe Channel. 21 refs., 10 figs., 60 tabs.

  8. Commerce Committee to look at 'safe harbor'

    National Research Council Canada - National Science Library

    Heather Fleming

    1997-01-01

    .... The legislation would give the TV industry a choice either of adopting a content-based ratings system that labels the level of sex, violence and objectionable language in a program, or of moving...

  9. Gulfport Harbor, Mississippi. Final Environmental Impact Statement

    Science.gov (United States)

    1989-06-01

    valuable resources such as: oyster reefs wetland and submerged habitats commercial and sport fish habitats. Design and conduct a monitoring program to...sand community 0EIS-21 occupies over 70% of the study area. Although there are no oyster reefs within the study area, the Square Hanokerchief Shoal reef ...Texas and Veracruz , thence through the West Indies and Caribbean waters of Central America to northern South America. The species is intolerant of

  10. Floating-Harbor syndrome associated with middle ear abnormalities.

    Science.gov (United States)

    Hendrickx, Jan-Jaap; Keymolen, Kathelijn; Desprechins, Brigitte; Casselman, Jan; Gordts, Frans

    2010-01-01

    Floating-Harbor syndrome is a rare syndrome of unknown etiology, which was first described in 1973. A triad of main features characterizes Floating-Harbor syndrome: short stature, characteristic face, and an expressive speech delay. We present a patient in whom the hearing thresholds improved insufficiently after placement of grommets. High-resolution CT scan of the temporal bone showed a prominent soft-tissue thickening suspected of causing fixation of the malleus, and fusion of the malleus head with the body of the incus. To our knowledge this is the first reported abnormal middle ear anatomy in a patient with Floating-Harbor syndrome. A conservative treatment with hearing aids was preferred as an initial treatment in favor of a surgical exploration.

  11. 78 FR 75961 - Energy Conservation Program: Test Procedures for Electric Motors

    Science.gov (United States)

    2013-12-13

    ... electric motors. 73 FR 78220. After considering comments from interested parties, DOE finalized key... for Electric Motors; Final Rule #0;#0;Federal Register / Vol. 78 , No. 240 / Friday, December 13, 2013... Program: Test Procedures for Electric Motors AGENCY: Office of Energy Efficiency and Renewable Energy...

  12. Extrachromosomal deoxyribonucleic acid in R factor-harboring Enterobacteriaceae

    DEFF Research Database (Denmark)

    Møller, JK; Bak, AL; Christiansen, C

    1976-01-01

    Extrachromosomal deoxyribonucleic acid (DNA) from 24 different R factor-harboring Enterobacteriaceae was isolated and characterized by analytical ultracentrifugation and electron microscopy. The R factors represented 15 different patterns of transferable drug resistance found in enterobacteria from...... from 1.700 to 1.720 g/cm3. The majority of the bacteria contained extrachromosomal DNAs of various densities. Three-fourths of the R factors were classified as fi+. The investigation illustrates the extensive variability in the physical characteristics of plasmid DNA from R factor-harboring strains....

  13. Twenty-Fifth Annual Audio-Visual Aids Conference, Wednesday 9th to Friday 11th July 1975, Whitelands College, Putney SW15. Conference Preprints.

    Science.gov (United States)

    National Committee for Audio-Visual Aids in Education, London (England).

    Preprints of papers to be presented at the 25th annual Audio-Visual Aids Conference are collected along with the conference program. Papers include official messages, a review of the conference's history, and presentations on photography in education, using school broadcasts, flexibility in the use of television, the "communications…

  14. 76 FR 76871 - National Pearl Harbor Remembrance Day, 2011

    Science.gov (United States)

    2011-12-08

    ... mettle of a generation. In the wake of the bombing of our harbor and the crippling of our Pacific Fleet.... Patriots across our country answered the call to defend our way of life at home and abroad. They crossed... civilians supported the war effort by repairing wrecked battleships, working in factories, and joining...

  15. Buffalo Harbor Study. Preliminary Feasibility Report. Volume II. Appendices.

    Science.gov (United States)

    1983-04-01

    Great Lakes, from cheap energy at nearby Niagara Falls, and from its railroad links to the great markets of North America. The opening of the Panama ...vious years. (Sweeny and Merckel: 1972). A 1977 benthic study of Buffalo Harbor showed the family Chironomidae was the most diverse group followed by

  16. Buffalo Harbor Study. Preliminary Feasibility Report. Volume I. Main Report.

    Science.gov (United States)

    1983-04-01

    between 1933-1937 of 98 million bushels (Barrick, 1970). The opening of the Panama Canal in 1914, the growing use of alternative inland waterways, and...Sweeny and Merckel: 1972). A 1977 benthic study of Buffalo Harbor showed the family Chironomidae was the most diverse group followed by Tubificidae and

  17. 78 FR 21597 - Marine Mammals: Alaska Harbor Seal Habitats

    Science.gov (United States)

    2013-04-11

    ... needed, and if so, what types of measures should be considered. DATES: We will conduct public workshops... for pupping, nursing, resting, and molting, and to limit vessel disturbance to harbor seals in those habitats. We will conduct two public workshops to inform interested parties of the ANPR and receive written...

  18. The floating harbor syndrome with cardiac septal defect.

    Science.gov (United States)

    Lazebnik, N; McPherson, E; Rittmeyer, L J; Mulvihill, J J

    1996-12-18

    The Floating Harbor syndrome of short stature, very delayed bone age, expressive language delay, and characteristic facial changes has not been associated with cardiac anomalies, except for one patient with pulmonic stenosis. We report on a 10-year-old boy with the syndrome and tetralogy of Fallot with atrial septal defect.

  19. Further observations on the Floating-Harbor syndrome.

    Science.gov (United States)

    Houlston, R S; Collins, A L; Dennis, N R; Temple, I K

    1994-04-01

    We report two unrelated female patients aged 2- and 15-years-old with short stature, language delay and craniofacial anomalies consistent with the Floating-Harbor syndrome. One patient had evidence of coeliac disease. This increasingly recognized association suggests pleiotropism.

  20. Respiratory properties of blood in the harbor porpoise, Phocoena phocoena

    DEFF Research Database (Denmark)

    Soegaard, Lisette B; Hansen, Marie N; van Elk, Cornelis

    2012-01-01

    . The true plasma non-bicarbonate buffer value was moderately higher than in terrestrial mammals and increased upon deoxygenation. Plasma bicarbonate was also relatively high, contributing to increase the overall buffer capacity. The apparent Cl(-) permeability of harbor porpoise erythrocytes was similar...

  1. Underwater Archaeological Investigations, Mobile Bay Ship Channel, Mobile Harbor, Alabama.

    Science.gov (United States)

    1986-05-01

    Resources Evaluation of Reef Shell Techniques, Mobile Bay, Alabama. Report to Radcliff Materials, Mobile. OSM, Moundsville , Alabama. * Mistovich, Tim S...Archaeological Consultants, Moundsville , Alabama. 1983b Cultural Resources Survey of Mobile Harbor, Alabama. index Volume. OSM Archaeological Consultants... Moundsville , Alabama. Muckelroy, Keith 1. 1978 Maritime Archaeology. Cambridge University, Cambridge. Otis, William . 1862 Articles of Agreement between

  2. Shoaling Analysis at Brazos Island, Harbor Inlet, Texas

    Science.gov (United States)

    2015-10-01

    SUPPLEMENTARY NOTES 14. ABSTRACT This Coastal and Hydraulics Engineering Technical Note (CHETN) describes channel shoaling analysis performed at...Texas by Ernest R. Smith, Tahirih C. Lackey, David B. King, and Richard Styles PURPOSE: This Coastal and Hydraulics Engineering Technical Note...CHETN) describes channel shoaling analysis performed at Brazos Island Harbor (BIH) Inlet, TX. The BIH entrance channel has experienced increased

  3. 78 FR 15669 - Marine Mammals: Alaska Harbor Seal Habitats

    Science.gov (United States)

    2013-03-12

    ... to observe animal behavior in the wild without causing disturbance. Each of the six NMFS Regions has... cause a change in the behavior of the animals. Viewers should avoid making the animals aware of their... behavior of harbor seals, which likely results in associated energetic costs to the animals. With frequent...

  4. Los Angeles and Long Beach Harbors Model Enhancement Program. Numerical Water Quality Model Study of Harbor Enhancements

    Science.gov (United States)

    1990-05-01

    034, Environmental Research Laboratory, US Environmental Protection Agency, Athens, GA. Chapra , S. C., and Reckhow, K. W. 1983. Engineering Approaches...A5 and A6 and integrating over the segment depth to obtain ( Chapra and Reckhow 1983) AL = 2 [exp (-a22.- exp (-a1)] (A7) yh where f = fractional

  5. A Comprehensive Copper Compliance Strategy: Implementing Regulatory Guidance at Pearl Harbor Naval Shipyard & Intermediate Maintenance Facility

    National Research Council Canada - National Science Library

    Earley, P. J; Rosen, G; Rivera-Duarte, I; Gauthier, R. D; Arias-Thode, Y; Thompson, J; Swope, B

    2007-01-01

    Studies were performed to develop a new National Pollution Discharge Elimination Systems Permit for the discharge of effluents from the Pearl Harbor Naval Shipyard and Intermediate Maintenance Facility into Pearl Harbor...

  6. Observed Haul-out Locations for Harbor Seals in Coastal Alaska

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Aerial surveys of coastal Alaska are the primary method for estimating abundance of harbor seals. A particular challenge associated with aerial surveys of harbor...

  7. Aerial Survey Counts of Harbor Seals in Coastal Alaska (1998-2002)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset supports efforts to estimate the abundance and trends in population size of Alaska harbor seals. Annual surveys of harbor seal populations are...

  8. Telemetry data from satellite tags deployed on harbor seals in Cook Inlet, Alaska

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Between 2004 and 2006 we conducted four harbor seal tagging trips in Cook Inlet during the months of October and May. In total, we captured and released 93 harbor...

  9. 77 FR 39630 - Special Local Regulations for Marine Events; Potomac River, National Harbor Access Channel, MD

    Science.gov (United States)

    2012-07-05

    ... Harbor Access Channel, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast... and National Harbor Access Channel during the event. DATES: This rule is effective on July 8, 2012... ``Special Local Regulations for [[Page 39631

  10. Aerial Survey Counts of Harbor Seals in Coastal Alaska (2003-2011)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset supports efforts to estimate the abundance and trends in population size of Alaska harbor seals. Annual surveys of harbor seal populations are...

  11. Large-Scale Evaluation of Nickel Aluminide Rools In A Heat-Treat Furnace at Bethlehem Steel's (now ISG) Burns Harbor Plate Mill

    Energy Technology Data Exchange (ETDEWEB)

    John Mengel; Anthony Martocci; Larry Fabina; RObert Petrusha; Ronald Chango

    2003-09-01

    At Bethlehem Steel Burns Harbor Plate Division (now ISG Burns Harbor Plate Inc.)'s annealing furnace, new nickel aluminide intermetallic alloy rolls provide greater high-temperature strength and wear resistance compared to the conventional H series cast austenitic alloys currently used in the industry, Oak Ridge National Laboratory and Bethlehem (ISG) partnered under a U.S. Department of Energy, Office of Industrial Technology's Emerging Technology Deployment Program to demonstrate and evaluate the nickel aluminide intermetallic alloy rolls as part of an updated energy efficient large commercial annealing furnace system.

  12. A smart ROV solution for ship hull and harbor inspection

    Science.gov (United States)

    Reed, Scott; Wood, Jon; Vazquez, Jose; Mignotte, Pierre-Yves; Privat, Benjamin

    2010-04-01

    Hull and harbor infrastructure inspections are frequently performed manually and involve quite a bit of risk and human and monetary resources. In any kind of threat and resource constrained environment, this involves unacceptable levels of risk and cost. Modern Remotely Operated Vehicles are highly refined machines that provide features and capabilities previously unavailable. Operations once carried out by divers can now be carried out more quickly, efficiently and safely by smart enabled ROVs. ROVs are rapidly deployable and capable of continuous, reliable operations in adverse conditions. They also provide a stable platform on which multiple sensors may be mounted and utilized to meet the harbor inspection problem. Automated Control software provides ROV's and their pilots with the capability to inspect complex, constrained environments such as those found in a harbor region. This application and the user interface allow the ROV to automatically conduct complex maneuvers relative to the area being inspected and relieves the training requirements and work load for the pilot, allowing he or she to focus on the primary task of survey, inspection and looking for possible threats (such as IEDs, Limpet Mines, signs of sabotage, etc). Real-time sensor processing tools can be integrated into the smart ROV solution to assist the operator. Automatic Target Recognition (ATR) algorithms are used to search through the sensor data collected by the ROV in real time. These algorithms provide immediate feedback on possible threats and notify the operator of regions that may require manual verification. Sensor data (sonar or video) is also mosaiced, providing the operator with real-time situational awareness and a coverage map of the hull or seafloor. Detected objects may also be placed in the context of the large scale characteristics of the hull (or bottom or pilings) and localized. Within the complex areas such as the harbor pier pilings and the running gear of the ship, real

  13. Submarine Groundwater Discharge in Stony Brook Harbor, NY

    Science.gov (United States)

    Durand, J. M.; Young, C.; Wong, T.; Hanson, G. N.

    2012-12-01

    As nutrients can significantly impact coastal ecosystems, understanding their path to embayments and oceans is crucial. In Stony Brook Harbor (Long Island, NY), submarine groundwater discharge (SGD) is the only significant contribution of freshwater and thus constitutes the main pathway for nutrients, which may eventually reach Long Island Sound. Subterranean estuaries have been shown to be highly reactive zones where nitrogen attenuation can occur. Understanding the fate of nitrogen in Stony Brook Harbor requires knowing the volume of groundwater entering the bay as well as the amount of denitrification, in the context of the hydrogeological framework. This is achieved by combining electrical resistivity survey, water sampling in piezometers, point conductivity and seepage measurements. A Trident probe inserted 60 cm deep into the sediments allows measuring the conductivity and temperature of the sediments and the overlying seawater. In spring 2011, five Trident transects spreading across the head of the harbor were used as a preliminary study to reveal potential locations for SGD. Locations with significant difference between sediment and seawater temperature and/or conductivities were further investigated using an AGI SuperSting 8-channel receiver resistivity meter. Two ultrasonic seepage meters were deployed in May and July 2011 about 20 m below the low tide mark. Five piezometers were aligned parallel to one resistivity survey. Our resistivity data indicate superficial mixing in the intertidal zone. The freshwater extends quite far under the seafloor, above 67 meters after the low tide mark for one location. The freshwater/saltwater interface seems to be almost horizontal. The piezometer data agree relatively well with the resistivity data. The preliminary average seepage rates observed vary from 3 to 60 cm/d. The resistivity sections reveal the presence of a thin layer of high conductivity above the low tide mark. This matches the observation of a superficial

  14. 33 CFR 334.1430 - Apra Inner Harbor, Island of Guam; restricted area.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Apra Inner Harbor, Island of Guam... THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.1430 Apra Inner Harbor, Island of Guam; restricted area. (a) The restricted area. The waters within Apra Inner Harbor and...

  15. 33 CFR 165.1404 - Apra Harbor, Guam-security zone.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Apra Harbor, Guam-security zone... Navigation Areas and Limited Access Areas Fourteenth Coast Guard District § 165.1404 Apra Harbor, Guam—security zone. (a) The following is designated as Security Zone C—The waters of Apra Outer Harbor, Guam...

  16. 77 FR 43513 - Olympia Harbor Days Tug Boat Races, Budd Inlet, WA

    Science.gov (United States)

    2012-07-25

    ... SECURITY Coast Guard 33 CFR Part 100 Olympia Harbor Days Tug Boat Races, Budd Inlet, WA AGENCY: Coast Guard... Local Regulation, Olympia Harbor Days Tug Boat Races, Budd Inlet, WA from 12 p.m. through 8 p.m. on... notice of enforcement of the Special Local Regulation for Olympia Harbor Days Tug Boat Races, Budd Inlet...

  17. 77 FR 45239 - Amendment of Class E Airspace; Bar Harbor, ME

    Science.gov (United States)

    2012-07-31

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Bar Harbor, ME AGENCY... airspace area at Bar Harbor, ME, as the Surry Non-Directional Radio Beacon (NDB) has been decommissioned... rulemaking to amend Class E airspace at Bar Harbor, ME (77 FR 27666) Docket No. FAA-2011-1366. Interested...

  18. 78 FR 38000 - Special Local Regulations; Marine Events, Spa Creek and Annapolis Harbor; Annapolis, MD

    Science.gov (United States)

    2013-06-25

    ...--AA08 Special Local Regulations; Marine Events, Spa Creek and Annapolis Harbor; Annapolis, MD AGENCY...,'' a marine event to be held on the waters of Spa Creek and Annapolis Harbor on July 20, 2013. The...; Marine Events, Spa Creek and Annapolis Harbor; Annapolis, MD'' in the Federal Register (78 FR 20066). The...

  19. 78 FR 20849 - Special Local Regulations; Marine Events, Potomac River; National Harbor Access Channel, MD

    Science.gov (United States)

    2013-04-08

    ...; National Harbor Access Channel, MD AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY... Potomac River federal navigation channel and the National Harbor Access Channel. C. Discussion of Proposed... Harbor Access Channel and includes the waters of the Potomac River, from shoreline to shoreline, bounded...

  20. 77 FR 25106 - Special Local Regulations for Marine Events; Potomac River, National Harbor Access Channel, MD

    Science.gov (United States)

    2012-04-27

    ... River, National Harbor Access Channel, MD AGENCY: Coast Guard, DHS. ACTION: Notice of proposed... navigation channel and the National Harbor Access Channel. Due to the need for vessel control during the... through the regulated area, including the National Harbor Access Channel, will only be allowed to safely...

  1. 75 FR 38019 - Safety Zone; Fixed Mooring Balls, South of Barbers Pt. Harbor Channel, Oahu, HI

    Science.gov (United States)

    2010-07-01

    .... Harbor Channel, Oahu, HI AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: Due to the..., approximately 2,500 yards south of Barbers Point Harbor channel buoy 2, Oahu, Hawaii. Entry of persons, vessels... Safety Zone; Fixed Mooring Balls, South of Barbers Pt Harbor Channel, Oahu, Hawaii. (a) Location. The...

  2. Integrated sediment decontamination for the New York/New Jersey Harbor

    Energy Technology Data Exchange (ETDEWEB)

    Stern, W.A. [Environmental Protection Agency, New York, NY (United States); Donato, K.R. [Army Corps of Engineers, New York, NY (United States); Clesceri, N.L. [Rensselaer Polytechnic Inst., Troy, NY (United States); Jones, K.W. [Brookhaven National Lab., Upton, NY (United States)

    1998-02-01

    Disposal of dredged material taken from the New York/New Jersey (NY/NJ) Harbor is problematic because of the presence of inorganic and organic contaminants that under revised testing criteria render it unsuitable for return to the ocean or for beneficial reuse. Decontamination of the dredged material followed by beneficial reuse is one attractive component of the overall comprehensive dredged material management plan being developed by the US Army Corps of Engineers New York District. A demonstration program to validate decontamination processes and to bring them into full-scale use in the NY/NJ Harbor is now in progress. Tests of selected technologies have been completed at the bench scale and pilot-scale (2--15 m{sup 3}) levels. Procedures for demonstration testing on scales from 750 m{sup 3} to 75,000 m{sup 3} are being developed with the goal of producing a useable decontamination system by the end of 1999. The overall project goals and present status of the project are reviewed here.

  3. Hydrocarbon pollutants shape bacterial community assembly of harbor sediments.

    Science.gov (United States)

    Barbato, Marta; Mapelli, Francesca; Magagnini, Mirko; Chouaia, Bessem; Armeni, Monica; Marasco, Ramona; Crotti, Elena; Daffonchio, Daniele; Borin, Sara

    2016-03-15

    Petroleum pollution results in co-contamination by different classes of molecules, entailing the occurrence of marine sediments difficult to remediate, as in the case of the Ancona harbor (Mediterranean Sea, Italy). Autochthonous bioaugmentation (ABA), by exploiting the indigenous microbes of the environment to be treated, could represent a successful bioremediation strategy. In this perspective we aimed to i) identify the main drivers of the bacterial communities' richness in the sediments, ii) establish enrichment cultures with different hydrocarbon pollutants evaluating their effects on the bacterial communities' composition, and iii) obtain a collection of hydrocarbon degrading bacteria potentially exploitable in ABA. The correlation between the selection of different specialized bacterial populations and the type of pollutants was demonstrated by culture-independent analyses, and by establishing a collection of bacteria with different hydrocarbon degradation traits. Our observations indicate that pollution dictates the diversity of sediment bacterial communities and shapes the ABA potential in harbor sediments. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Hydrocarbon pollutants shape bacterial community assembly of harbor sediments

    KAUST Repository

    Barbato, Marta

    2016-02-02

    Petroleum pollution results in co-contamination by different classes of molecules, entailing the occurrence of marine sediments difficult to remediate, as in the case of the Ancona harbor (Mediterranean Sea, Italy). Autochthonous bioaugmentation (ABA), by exploiting the indigenous microbes of the environment to be treated, could represent a successful bioremediation strategy. In this perspective we aimed to i) identify the main drivers of the bacterial communities\\' richness in the sediments, ii) establish enrichment cultures with different hydrocarbon pollutants evaluating their effects on the bacterial communities\\' composition, and iii) obtain a collection of hydrocarbon degrading bacteria potentially exploitable in ABA. The correlation between the selection of different specialized bacterial populations and the type of pollutants was demonstrated by culture-independent analyses, and by establishing a collection of bacteria with different hydrocarbon degradation traits. Our observations indicate that pollution dictates the diversity of sediment bacterial communities and shapes the ABA potential in harbor sediments.

  5. The defining DNA methylation signature of Floating-Harbor Syndrome

    OpenAIRE

    Hood, Rebecca L.; Schenkel, Laila C.; Nikkel, Sarah M.; Ainsworth, Peter J.; Pare, Guillaume; Boycott, Kym M.; Bulman, Dennis E.; Sadikovic, Bekim

    2016-01-01

    Floating-Harbor syndrome (FHS) is an autosomal dominant genetic condition characterized by short stature, delayed osseous maturation, expressive language impairment, and unique facial dysmorphology. We previously identified mutations in the chromatin remodeling protein SRCAP (SNF2-related CBP Activator Protein) as the cause of FHS. SRCAP has multiple roles in chromatin and transcriptional regulation; however, specific epigenetic consequences of SRCAP mutations remain to be described. Using hi...

  6. Floating Harbor syndrome. Case report and further syndrome delineation.

    Science.gov (United States)

    Midro, A T; Olchowik, B; Rogowska, M; Hubert, E; Hassman-Poznańska, E; Papasz, A; Szulc, S; Wiśniewski, A

    1997-01-01

    Floating Harbor syndrome was diagnosed in a 9 years old girl on the basis of short stature, delayed bone age, mild mental retardation, speech problems and specific craniofacial features. A detailed phenotype description is given and evaluated together with 18 other published case reports according to the concept of the Munich Dysmorphology Database (Stengel-Rutkowski et al., 1996) with the aim to delineate the spectrum of clinical and anthropological features.

  7. Public Works Center Pearl Harbor Fleet Moorings Underwater Inspection Plan.

    Science.gov (United States)

    1983-04-15

    AOA17 6 228 PUBLIC MORKS CENTER PERL HARBO FLEET MOORINGS 1/1 UNDERWATER INSPECTION PLAN(O) NAVAL FACILITIES ENGINEERING COMMAND WASHINGTON DC...PUBLIC WORKS .......... CENTER.... ..... PEARL HARBOR.... 00~ D...... CENRWTTE E 4PAR INSPCTIO voOEA ENGINEEORINS *...... AND.. COSTUCIN.ROET.FFC...Public Works Center Pearl Habor F’aet Moorings Underwater Inspection Plan 12. PERSONAL AUTHOR(S) 13a. TYPE OF REPORT 13b. TIME COVERED 14. DATE OF

  8. Fine-scale variability in harbor seal foraging behavior.

    Directory of Open Access Journals (Sweden)

    Kenady Wilson

    Full Text Available Understanding the variability of foraging behavior within a population of predators is important for determining their role in the ecosystem and how they may respond to future ecosystem changes. However, such variability has seldom been studied in harbor seals on a fine spatial scale (<30 km. We used a combination of standard and Bayesian generalized linear mixed models to explore how environmental variables influenced the dive behavior of harbor seals. Time-depth recorders were deployed on harbor seals from two haul-out sites in the Salish Sea in 2007 (n = 18 and 2008 (n = 11. Three behavioral bout types were classified from six dive types within each bout; however, one of these bout types was related to haul-out activity and was excluded from analyses. Deep foraging bouts (Type I were the predominant type used throughout the study; however, variation in the use of bout types was observed relative to haul-out site, season, sex, and light (day/night. The proportional use of Type I and Type II (shallow foraging/traveling bouts differed dramatically between haul-out sites, seasons, sexes, and whether it was day or night; individual variability between seals also contributed to the observed differences. We hypothesize that this variation in dive behavior was related to habitat or prey specialization by seals from different haul-out sites, or individual variability between seals in the study area. The results highlight the potential influence of habitat and specialization on the foraging behavior of harbor seals, and may help explain the variability in diet that is observed between different haul-out site groups in this population.

  9. Towards an ethics safe harbor for global biomedical research

    OpenAIRE

    Dove, Edward S; Knoppers, Bartha M.; Zawati, Ma'n H

    2014-01-01

    Although increasingly global, data-driven genomics and other ?omics?-focused research hold great promise for health discoveries, current research ethics review systems around the world challenge potential improvements in human health from such research. To overcome this challenge, we propose a ?Safe Harbor Framework for International Ethics Equivalency? that facilitates the harmonization of ethics review of specific types of data-driven international research projects while respecting globall...

  10. Los Angeles Beach Harbors, Los Angeles County, California.

    Science.gov (United States)

    1974-10-01

    Pacific jack mackerel, sardines and corbina. 2.69 The Port of Los Angeles is extensively used as a base for both sport and commercial boats that carry...concentrations of cadmium , chromium, lead, and nickel and other metals found in seawater, (b) the concentrations of these heavy metals found in some harbor...sediment cores be taken throughout the project area, penetrating the sediment to project depth. The analyses of these samples for mercury, cadmium

  11. Towards an ethics safe harbor for global biomedical research

    Science.gov (United States)

    Dove, Edward S.; Knoppers, Bartha M.; Zawati, Ma'n H.

    2014-01-01

    Although increasingly global, data-driven genomics and other ‘omics’-focused research hold great promise for health discoveries, current research ethics review systems around the world challenge potential improvements in human health from such research. To overcome this challenge, we propose a ‘Safe Harbor Framework for International Ethics Equivalency’ that facilitates the harmonization of ethics review of specific types of data-driven international research projects while respecting globally transposable research ethics norms and principles. The Safe Harbor would consist in part of an agency supporting an International Federation for Ethics Review (IFER), formed by a voluntary compact among countries, granting agencies, philanthropies, institutions, and healthcare, patient advocacy, and research organizations. IFER would be both a central ethics review body, and also a forum for review and follow-up of policies concerning ethics norms for international research projects. It would be built on five principle elements: (1) registration, (2) compliance review, (3) recognition, (4) monitoring and enforcement, and (5) public participation. The Safe Harbor would create many benefits for researchers, countries, and the general public, and may eventually have application beyond (gen)omics to other areas of biomedical research that increasingly engage in secondary use of data and present only negligible risks. PMID:27774154

  12. Collaborative Undergraduate HBCU Student Summer Training Program Award

    Science.gov (United States)

    2014-06-01

    outcomes. Dr. Brown initiated many of the laparoscopic and robotic programs at his former institution, the Medical College of Georgia, and currently...Saturday Night Concert Series – Free musical concerts held each Friday and Saturday night from 6:30 to 9:30 pm on the downtown Pedestrian Mall...festival will be held on the Pentacrest on the campus of the University of Iowa. Thursday Night Concerts in Coralville – These musical concerts

  13. 77 FR 41909 - Safety Zone; Port of Dutch Harbor; Dutch Harbor, AK

    Science.gov (United States)

    2012-07-17

    ... sea due to additional vessel traffic associated with exploratory drilling operations in the Chukchi... with planned offshore drilling operations in the Chukchi and Beaufort Seas during a period of time that... docket, call Renee V. Wright, Program Manager, Docket Operations, telephone 202-366-9826. SUPPLEMENTARY...

  14. Islām al-kāfir fī ḥāl al-khuṭba: concerning the conversion of “infidels” to Islam during the Muslim Friday sermon in Mamluk Egypt

    Directory of Open Access Journals (Sweden)

    Jones, Linda G.

    2012-06-01

    Full Text Available Ibn al-Ḥājj al-‘Abdarī a Maliki jurist in Mamluk Cairo, denounced a religious “innovation” (bid‘a that had apparently become current in fourteenthcentury Egypt: “Infidels” would interrupt the Muslim Friday sermon in order to profess or reiterate their conversion to Islam before the entire congregation. Ibn al-Ḥājj urged preachers not to tolerate such interruptions under any circumstances, a posture that seems at odd with Mamluk policy of inducing such conversions especially among the Coptic community. The Maliki jurist’s legal arguments furnish new insights into the hitherto unexplored role of the Friday liturgical sermon in the conversion to Islam. This article will explain the legal basis of Ibn al-Ḥājj’s opposition to this practice, propose some explanations for the motivations behind the would-be convert’s interruption of the sermon, and relate this phenomenon to the historical context of tense Muslim-Christian relations in fourteenth-century Mamluk Egypt.

    Ibn al-Ḥaŷŷ al-‘Abdarī, un jurista malikí en el Cairo mameluco, denunció una “innovación religiosa” (bid‘a que se extendió en el Egipto del siglo XIV. Los “infieles” interrumpían el sermón del viernes, aparentemente, para proclamar o reiterar su conversión al Islam ante la congregación. Ibn al-Ḥaŷŷ instó a los predicadores a no tolerar dichas interrupciones bajo ninguna circunstancia –postura que parece contradecir a la política impuesta por los mamelucos de forzar la conversión de los infieles, sobre todo de los procedentes de la comunidad copta. Los argumentos legales de Ibn al-Ḥaŷŷ arrojan nueva luz sobre el papel, hasta entonces ignorado por los estudiosos, del sermón del viernes en la conversión al islam. El artículo analiza las bases jurídicas de la oposición manifestada por Ibn al-Ḥaŷŷ hacia esta práctica, explica los posibles motivos que indujeron a los conversos a interrumpir el serm

  15. Following the terrorist attacks recently committed in the United States of America, and according to the recommendations of the Council of the European Union, the CERN staff observed 3 minutes of silence on Friday 14 September 2001 at 12h00, as a sign of deepest sympathy for all the victims and their families, and of solidarity with the American people

    CERN Multimedia

    Maximilien Brice

    2001-01-01

    Following the terrorist attacks recently committed in the United States of America, and according to the recommendations of the Council of the European Union, the CERN staff observed 3 minutes of silence on Friday 14 September 2001 at 12h00, as a sign of deepest sympathy for all the victims and their families, and of solidarity with the American people

  16. Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa visiting ALICE experiment on 1st November 2007 with CERN Director-General R. Aymar and Adviser J.-P. Revol. Thursday, 1st and Friday, 2nd November 2007

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa visiting ALICE experiment on 1st November 2007 with CERN Director-General R. Aymar and Adviser J.-P. Revol. Thursday, 1st and Friday, 2nd November 2007

  17. Sediment Budget for the Indiana Shore from Michigan City Harbor to Burns Waterway Harbor

    Science.gov (United States)

    2012-08-01

    former sand dunes and slag (the vitreous residue left after smelting ore)). USACE Chicago (2010) summarized the history of the NIPSCO Bailly Generating...lakefill disposal site for slag . Along the shoreline, additional sand had been trapped east of the NIPSCO BGS outfall canal, and the shore had...Baldy has averaged 45,000 yd3/year since the annual nourishment program began in 1996, and the beach and shoreface have stabilized . Sand now covers the

  18. Sediment toxicity in Boston Harbor: Magnitude, extent, and relationships with chemical toxicants. Technical memo

    Energy Technology Data Exchange (ETDEWEB)

    Long, E.R.; Sloane, G.M.; Carr, R.S.; Scott, K.J.; Thursby, G.B.

    1996-06-01

    A survey of the toxicity of sediments throughout Boston Harbor and vicinity was conducted by NOAA`s National Status and Trends (NS&T) Program. The objectives of the survey were to determine the magnitude and spatial extent of toxicity and the relationship between measures of toxicity and the concentrations of chemical toxicants in the sediments. Multiple toxicity tests were performed including: an amphipod survival test performed with whole sediments, a microbial bioluminescence test performed with organic solvent extracts of the sediments, and sea urchin fertilization and embryological development tests performed with the pore waters extracted from the sediments. Chemical analyses were performed on selected samples for trace metals, polynuclear aromatic hydrcarbons, chlorinated pesticides, PCBs, and butyltins.

  19. Free-Living and Plankton-Associated Vibrios: Assessment in Ballast Water, Harbor Areas, and Coastal Ecosystems in Brazil

    Science.gov (United States)

    Rivera, Irma N. G.; Souza, Keili M. C.; Souza, Claudiana P.; Lopes, Rubens M.

    2013-01-01

    Ballast water (BW) is a major transport vector of exotic aquatic species and pathogenic microorganisms. The wide-ranging spread of toxigenic Vibrio cholerae O1 from harbor areas has been frequently ascribed to discharge of contaminated BW into eutrophic coastal environments, such as during the onset of the seventh cholera pandemic in South America in the early 1990s. To determine the microbiological hazards of BWs transported to Brazilian ports, we evaluated water and plankton samples taken from (i) BW tanks of recently arrived ships, (ii) port areas along the Brazilian coastline from ∼1 to 32°S and (iii) three coastal areas in São Paulo State. Vibrio concentration and toxigenic V. cholerae O1 occurrence were analyzed. Plankton-associated vibrios were more abundant than free-living vibrios in all studied environments. V. cholerae was found in 9.5% of ballast tanks and 24.2% of port samples, both as free-living and attached forms and, apart from the Santos harbor, was absent off São Paulo State. Toxigenic V. cholerae O1 isolates (ctxA+, tcpA+), involved in cholera disease, were found in BW (2%) and harbor (2%) samples. These results confirm that BW is an important carrier of pathogenic organisms, and that monitoring of vibrios and other plankton-attached bacteria is of paramount importance in BW management programs. PMID:23335920

  20. Free-living and plankton-associated vibrios: assessment in ballast water, harbor areas, and coastal ecosystems in Brazil.

    Science.gov (United States)

    Rivera, Irma N G; Souza, Keili M C; Souza, Claudiana P; Lopes, Rubens M

    2012-01-01

    Ballast water (BW) is a major transport vector of exotic aquatic species and pathogenic microorganisms. The wide-ranging spread of toxigenic Vibrio cholerae O1 from harbor areas has been frequently ascribed to discharge of contaminated BW into eutrophic coastal environments, such as during the onset of the seventh cholera pandemic in South America in the early 1990s. To determine the microbiological hazards of BWs transported to Brazilian ports, we evaluated water and plankton samples taken from (i) BW tanks of recently arrived ships, (ii) port areas along the Brazilian coastline from ∼1 to 32°S and (iii) three coastal areas in São Paulo State. Vibrio concentration and toxigenic V. cholerae O1 occurrence were analyzed. Plankton-associated vibrios were more abundant than free-living vibrios in all studied environments. V. cholerae was found in 9.5% of ballast tanks and 24.2% of port samples, both as free-living and attached forms and, apart from the Santos harbor, was absent off São Paulo State. Toxigenic V. cholerae O1 isolates (ctxA(+), tcpA(+)), involved in cholera disease, were found in BW (2%) and harbor (2%) samples. These results confirm that BW is an important carrier of pathogenic organisms, and that monitoring of vibrios and other plankton-attached bacteria is of paramount importance in BW management programs.

  1. Restoration Science in New York Harbor: It takes a (large, diverse and engaged) village

    Science.gov (United States)

    Newton, R.; Birney, L.; Janis, S.; Groome, M.; Palmer, M.; Bone, E.; O'Neil, J. M.; Hill, J.; Dennison, W.; Malinowski, P.; Kohne, L.; Molina, M.; Moore, G.; Woods, N.

    2015-12-01

    The Curriculum + Community Enterprise for Restoration Science (CCE-RS) facilitates partnerships between scientists and middle school educators on ecological restoration and environmental monitoring projects. The educational model is designed to wrap around the student, including classroom instruction, field science, after-school programs and engagement with the student's community. Its pillars include: a teacher training fellowship at Pace University, student curriculum, a digital platform, afterschool and summer mentoring, and community exhibits. The digital platform includes a tablet app tailored to the project's field protocols and linked to a database shared across schools and partnering institutions. Through the digital platform, data is integrated into a single citizen-science monitoring project, teachers share curriculum and best practices, and students link directly to their peers at other schools. Curriculum development has been collaborative between scientists, science education specialists, and secondary school teachers. The CCE-RS is rooted in project-based learning: the New York Harbor School has engaged high school students in environmental monitoring and oyster restoration in the Harbor for about the last decade. The science partners (U. of Maryland and Columbia) have been working with students and other citizen scientists in outdoor science over about the last decade. Local partners in outside-the-classroom education include the New York Academy of Sciences, The River Project, which will provide field education services, and Good Shepherd Services, which provides after-school programming in schools serving primarily poor families. Scientists on the project engage directly with teachers and informal educators in curriculum development and citizen-science outreach. We present the lessons learned from our first cohort of Fellows, the pedagogical model, and the digital platform, which is extensible to other ecological restoration settings.

  2. Caffeine in Boston Harbor past and present, assessing its utility as a tracer of wastewater contamination in an urban estuary

    Science.gov (United States)

    Sites throughout Boston Harbor were analyzed for caffeine to assess its utility as a tracer in identifying sources of sanitary wastewater. Caffeine ranged from 15 ng/L in the outer harbor to a high of 185 ng/L in the inner harbor. Inner harbor concentrations were a result of comb...

  3. Quantitative Measures of Anthropogenic Noise on Harbor Porpoises

    DEFF Research Database (Denmark)

    Wisniewska, Danuta Maria; Teilmann, Jonas; Hermannsen, Line

    2016-01-01

    In recent years, several sound and movement recording tags have been developed to sample the acoustic fi eld experienced by cetaceans and their reactions to it. However, little is known about how tag placement and an animal’s orientation in the sound fi eld affect the reliability of on-animal...... recordings as proxies for actual exposure. Here, we quantify sound exposure levels recorded with a DTAG-3 tag on a captive harbor porpoise exposed to vessel noise in a controlled acoustic environment. Results show that fl ow noise is limiting onboard noise recordings, whereas no evidence of body shading has...

  4. Detailed neuropsychological evaluation in a patient with Floating Harbor syndrome.

    Science.gov (United States)

    Pouliquen, D; Goldenberg, A; Hannequin, D; Lecointre, C; Lechevallier, J; Cormier-Daire, V; Martinaud, O

    2012-01-01

    The Floating Harbor syndrome is a rare genetic disease characterized by a triad of clinical signs: specific dysmorphic facial features, short stature with delayed bone age, and language and speech disorders. These signs are, in most cases, associated with borderline normal intelligence to moderate delay concerning intellectual functioning. We report an extensive neuropsychological evaluation for an adult female patient and show, in particular, a severe visuospatial impairment. We discuss this deficit in the light of the previous reported cases and suggest that visuospatial abilities should be explored more systematically.

  5. Growth hormone deficiency: an unusual presentation of floating harbor syndrome.

    Science.gov (United States)

    Galli-Tsinopoulou, Assimina; Kyrgios, Ioannis; Emmanouilidou, Eleftheria; Maggana, Ioanna; Kotanidou, Eleni; Kokka, Paraskevi; Stylianou, Charilaos

    2011-01-01

    Floating-Harbor Syndrome (FHS) is a very rare condition of unknown etiology characterized by short stature, delayed bone age, characteristic facial features, delayed language skills and usually normal motor development. This syndrome has only once been associated with growth hormone deficiency and precocious puberty in the same patient. We describe a 5 4/12 year-old girl with the typical features of FHS in whom growth hormone deficiency was diagnosed and two years later central precocious puberty was noted. The patient showed a good response to human recombinant growth hormone as well as gonadotropin releasing hormone analogue treatment.

  6. Two more diagnostic signs in the Floating-Harbor syndrome.

    Science.gov (United States)

    Ala-Mello, S; Peippo, M

    1996-01-01

    A 6-year-old boy with the Floating-Harbor syndrome (F-HS) is described. We propose that his exceptionally high-pitched voice and supernumerary upper incisor are additional diagnostic signs of F-HS. The elevated gliadin antibody levels suggest coeliac disease, which has been described in three out of the 15 previously reported F-HS patients. His facial features and delayed speech development are very characteristic but his shortness (-3 SD) is milder than usual. The patient is a sporadic case like all the F-HS cases so far.

  7. Friday 29 August 2014 - Mrs G. Kopper

    CERN Document Server

    Brice, Maximilien

    2014-01-01

    Minister of Science, Technology and Telecommunications, Republic of Costa Rica G. Kopper signing the Guest Book with Director-General R. Heuer; throughout accompanied by Deputy Head of International Relations E. Tsesmelis and International Relations Adviser for Latin America J. Salicio.

  8. Friday Programme for CineGlobe 2015

    CERN Multimedia

    Marcelloni De Oliveira, Claudia

    2015-01-01

    Workshops, apero with filmmakers and short-films inspired by science were the menu of the festival through the day. At night the CineGlobe DOME shown with the 360 degree projections shot-films; among them the avant-premiere of "Phantom of the Universe" - a movie that explains Dark Matter, directed by Joao Pequenao. Meanwhile at the Globe, the audience could enjoy the projections of the sequence of " The Invisible Photograph" .

  9. Processes influencing the transport and fate of contaminated sediments in the coastal ocean: Boston Harbor and Massachusetts Bay

    Science.gov (United States)

    Alexander, P. Soupy; Baldwin, Sandra M.; Blackwood, Dann S.; Borden, Jonathan; Casso, Michael A.; Crusius, John; Goudreau, Joanne; Kalnejais, Linda H.; Lamothe, Paul J.; Martin, William R.; Martini, Marinna A.; Rendigs, Richard R.; Sayles, Frederick L.; Signell, Richard P.; Valentine, Page C.; Warner, John C.; Bothner, Michael H.; Butman, Bradford

    2007-01-01

    Most of the major urban centers of the United States including Boston, New York, Washington, Chicago, New Orleans, Miami, Los Angeles, San Francisco, and Seattle—are on a coast (fig. 1.1). All of these cities discharge treated sewage effluent into adjacent waters. In 2000, 74 percent of the U.S. population lived within 200 kilometers (km) of the coast. Between 1980 and 2002, the population density in coastal communities increased approximately 4.5 times faster than in noncoastal areas of the U.S. (Perkins, 2004). More people generate larger volumes of wastes, increase the demands on wastewater treatment, expand the area of impervious land surfaces, and use more vehicles that contribute contaminants to street runoff. According to the National Coastal Condition Report II (U.S. Environmental Protection Agency, 2005a), on the basis of coastal habitat, water and sediment quality, benthic index, and fish tissue, the overall national coastal condition is only poor to fair and the overall coastal condition in the highly populated Northeast is poor. Scientific information helps managers to prioritize and regulate coastal-ocean uses that include recreation, commercial fishing, transportation, waste disposal, and critical habitat for marine organisms. These uses are often in conflict with each other and with environmental concerns. Developing a strategy for managing competing uses while maintaining sustainability of coastal resources requires scientific understanding of how the coastal ocean system behaves and how it responds to anthropogenic influences. This report provides a summary of a multidisciplinary research program designed to improve our understanding of the transport and fate of contaminants in Massachusetts coastal waters. Massachusetts Bay and Boston Harbor have been a focus of U.S. Geological Survey (USGS) research because they provide a diverse geographic setting for developing a scientific understanding of the geology, geochemistry, and oceanography of

  10. New world bats harbor diverse influenza A viruses.

    Directory of Open Access Journals (Sweden)

    Suxiang Tong

    Full Text Available Aquatic birds harbor diverse influenza A viruses and are a major viral reservoir in nature. The recent discovery of influenza viruses of a new H17N10 subtype in Central American fruit bats suggests that other New World species may similarly carry divergent influenza viruses. Using consensus degenerate RT-PCR, we identified a novel influenza A virus, designated as H18N11, in a flat-faced fruit bat (Artibeus planirostris from Peru. Serologic studies with the recombinant H18 protein indicated that several Peruvian bat species were infected by this virus. Phylogenetic analyses demonstrate that, in some gene segments, New World bats harbor more influenza virus genetic diversity than all other mammalian and avian species combined, indicative of a long-standing host-virus association. Structural and functional analyses of the hemagglutinin and neuraminidase indicate that sialic acid is not a ligand for virus attachment nor a substrate for release, suggesting a unique mode of influenza A virus attachment and activation of membrane fusion for entry into host cells. Taken together, these findings indicate that bats constitute a potentially important and likely ancient reservoir for a diverse pool of influenza viruses.

  11. Grace Under Fire: The Army Nurses of Pearl Harbor, 1941.

    Science.gov (United States)

    Milbrath, Gwyneth R

    2016-01-01

    Much has been written about the military events of December 7, 1941; however, little has been documented about the nurses' work and experience at Pearl Harbor, Hawaii. The aerial assault on Pearl Harbor was the first time in US history that Army nurses had been on the front line of battle. Nurses quickly triaged and stabilized those who could be saved, and provided compassion and comfort to those who were dying, in an environment where the nurses were unsure of their own survival. Traditional historical methods and a social history framework were used in this investigation. Primary sources included oral histories from the US Army Medical Department Center of History and Heritage and the State of Hawaii's website, Hawaii Aviation. Secondary sources included published books, newspaper articles, military websites, and history texts. Due to the limited bed capacity, Hickam Field Hospital converted to an evacuation hospital. Nurses, physicians, and medical corpsman triaged, stabilized, and transported those likely to survive, while staging the dead behind the building. The emergency room at Tripler Hospital was quickly flooded with patients from the battlefield, but the staff was able to sort patients appropriately to the wards, to the operating room, or provide comfort care as they died. At Schofield Hospital, collaboration between tireless doctors, nurses, and corpsmen was key to providing life-saving surgery and care.

  12. The Portland Harbor Superfund Site Sustainability Project: Introduction.

    Science.gov (United States)

    Fitzpatrick, Anne G; Apitz, Sabine E; Harrison, David; Ruffle, Betsy; Edwards, Deborah A

    2018-01-01

    This article introduces the Portland Harbor Superfund Site Sustainability Project (PHSP) special series in this issue. The Portland Harbor Superfund Site is one of the "mega-sediment sites" in the United States, comprising about 10 miles of the Lower Willamette River, running through the heart of Portland, Oregon. The primary aim of the PHSP was to conduct a comprehensive sustainability assessment, integrating environmental, economic, and social considerations of a selection of the remedial alternatives laid out by the US Environmental Protection Agency. A range of tools were developed for this project to quantitatively address environmental, economic, and social costs and benefits based upon diverse stakeholder values. In parallel, a probabilistic risk assessment was carried out to evaluate the risk assumptions at the core of the remedial investigation and feasibility study process. Integr Environ Assess Manag 2018;14:17-21. © 2017 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC). © 2017 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

  13. New World Bats Harbor Diverse Influenza A Viruses

    Science.gov (United States)

    Tong, Suxiang; Zhu, Xueyong; Li, Yan; Shi, Mang; Zhang, Jing; Bourgeois, Melissa; Yang, Hua; Chen, Xianfeng; Recuenco, Sergio; Gomez, Jorge; Chen, Li-Mei; Johnson, Adam; Tao, Ying; Dreyfus, Cyrille; Yu, Wenli; McBride, Ryan; Carney, Paul J.; Gilbert, Amy T.; Chang, Jessie; Guo, Zhu; Davis, Charles T.; Paulson, James C.; Stevens, James; Rupprecht, Charles E.; Holmes, Edward C.; Wilson, Ian A.; Donis, Ruben O.

    2013-01-01

    Aquatic birds harbor diverse influenza A viruses and are a major viral reservoir in nature. The recent discovery of influenza viruses of a new H17N10 subtype in Central American fruit bats suggests that other New World species may similarly carry divergent influenza viruses. Using consensus degenerate RT-PCR, we identified a novel influenza A virus, designated as H18N11, in a flat-faced fruit bat (Artibeus planirostris) from Peru. Serologic studies with the recombinant H18 protein indicated that several Peruvian bat species were infected by this virus. Phylogenetic analyses demonstrate that, in some gene segments, New World bats harbor more influenza virus genetic diversity than all other mammalian and avian species combined, indicative of a long-standing host-virus association. Structural and functional analyses of the hemagglutinin and neuraminidase indicate that sialic acid is not a ligand for virus attachment nor a substrate for release, suggesting a unique mode of influenza A virus attachment and activation of membrane fusion for entry into host cells. Taken together, these findings indicate that bats constitute a potentially important and likely ancient reservoir for a diverse pool of influenza viruses. PMID:24130481

  14. Environmental benefits of Boston Harbor clean-up projects

    Energy Technology Data Exchange (ETDEWEB)

    Connor, M.S.; Smith, W.M. (Massachusetts Water Resources Authority, Boston (United States))

    1990-01-09

    The Massachusetts Water Resources Authority has undertaken one of the largest public works projects in the country to control the pollution of Boston Harbor. The project includes construction of a new primary and secondary treatment plant and sludge treatment facilities, excavation of a long ocean outfall and diffuser, and a solution to the overflow of mixed sewage and stormwater during storms; it will take over twenty years and billions of dollars to construct. A comparison of the relative costs and environmental benefits of relative costs and environmental benefits of the various construction projects, and other pollution control strategies, shows that some projects are more cost-effective than others for solving specific pollution problems. The capture and treatment of combined sewer overflow (CSO) will result in a more dramatic reduction of pathogen contamination than will completion of the primary and secondary treatment plants. Although the flow of raw sewage is intermittent and relatively small, it has high concentrations of bacteria and viruses. On the other hand, the new treatment plants will be more important in reducing toxic contamination of fish and shellfish. In summary, all the planned clean-up projects appear to be necessary to reach the goal of a swimmable, fishable Boston Harbor.

  15. Polycyclic aromatic hydrocarbons and trace elements bounded to airborne PM10 in the harbor of Volos, Greece: Implications for the impact of harbor activities

    Science.gov (United States)

    Manoli, E.; Chelioti-Chatzidimitriou, A.; Karageorgou, K.; Kouras, A.; Voutsa, D.; Samara, C.; Kampanos, I.

    2017-10-01

    Harbors are often characterized by high levels of air pollutants that are emitted from ship traffic and other harbor activities. In the present study, the concentrations of Polycyclic Aromatic Hydrocarbons (PAHs) and trace elements (As, Cd, Ni, Pb, Cr, Mn, Zn, and Fe) bounded to the inhalable particulate matter PM10 were studied in the harbor of Volos, central Greece, during a 2-year period (2014-2015). Seasonal and daily variations were investigated. Moreover, total carcinogenic and mutagenic activities of PAHs were calculated. The effect of major wind sectors (sea, city, industrial, harbor) was estimated to assess the potential contribution of ship traffic and harbor activities, such as scrap metal handling operations. Results showed that the harbor sector (calm winds ≤ 0.5 m s-1) was associated with the highest concentrations of PM10. The harbor sector was also associated with relatively increased levels of trace elements (As, Fe, Cr, Mn, Ni), however the effect of this sector was lower than the corresponding effect of the industrial wind sector. The sea sector showed only a slight increase in B[a]Py and Σ12PAHs, whereas the highest increasing effect for PAHs and traffic-related elements, such as Pb and Zn, was evidenced for the city sector.

  16. Final Definite Project Report and Final Environmental Assessment, Keystone Harbor Channel Deepening, Admiralty Inlet, Washington

    Science.gov (United States)

    1991-10-01

    acres, or about 206 square miles, and is comprised of Whidbey and Camano Islands . The terrain is rolling with higher hills ranging from 400 to 500...Inlet, Washington. The Washington State Department of Transportation (WDOT) operates an automobile ferry from Keystone Harbor on Whidbey Island to Port...at Keystone Harbor, Whidbey Island , was conducted under the authority of Section 107 of the 1960 River and Harbor Act, as amended. Section 107

  17. Influenza A(H10N7) Virus in Dead Harbor Seals, Denmark

    DEFF Research Database (Denmark)

    Krog, Jesper Schak; Hansen, Mette Sif; Holm, Elisabeth

    2015-01-01

    Since April 2014, an outbreak of influenza in harbor seals has been ongoing in northern Europe. In Denmark during June-August, 152 harbor seals on the island of Anholt were found dead from severe pneumonia. We detected influenza A(H10N7) virus in 2 of 4 seals examined.......Since April 2014, an outbreak of influenza in harbor seals has been ongoing in northern Europe. In Denmark during June-August, 152 harbor seals on the island of Anholt were found dead from severe pneumonia. We detected influenza A(H10N7) virus in 2 of 4 seals examined....

  18. Ecological evaluation of proposed discharge of dredged material from Oakland Harbor into ocean waters (Phase 3 B of -42-foot project). Volume 2, Appendixes

    Energy Technology Data Exchange (ETDEWEB)

    Kohn, N.P.; Ward, J.A.; Mayhew, H.L.; Word, J.Q.; Barrows, E.S.; Goodwin, S.M.; Lefkovitz, L.F. [Battelle/Marine Sciences Lab., Sequim, WA (United States)

    1992-06-01

    The Water Resources Development Act of 1986 (Public Law 99-662) authorized the US Army Corps of Engineers (USACE) San Francisco District, to deepen and widen the navigational channels of the Oakland Inner and Outer Harbors to accommodate deeper-draft vessels. The USACE is considering several disposal options for the dredged material removed during these channel improvements including open-water disposal. Dredged material proposed for open-water disposal must be evaluated to determine the potential impacts of the disposal activity on the water column and disposal site environments. The USACE requested that Battelle/Marine Sciences Laboratory (MSL) conduct studies to evaluate open-water disposal options for Oakland Harbor sediments. This request developed into the Oakland Harbor Phase III Program. This is Volume 2 of a two-volume report that presents information gathered to determine the suitability of ocean disposal of sediments dredged from Oakland Harbor. This volume contains the Appendixes (A through N), which provide details of the data analyses and full presentation of the data and results.

  19. Ecological evaluation of proposed discharge of dredged material from Oakland Harbor into ocean waters (Phase 3 B of -42-foot project)

    Energy Technology Data Exchange (ETDEWEB)

    Kohn, N.P.; Ward, J.A.; Mayhew, H.L.; Word, J.Q.; Barrows, E.S.; Goodwin, S.M.; Lefkovitz, L.F. (Battelle/Marine Sciences Lab., Sequim, WA (United States))

    1992-06-01

    The Water Resources Development Act of 1986 (Public Law 99-662) authorized the US Army Corps of Engineers (USACE) San Francisco District, to deepen and widen the navigational channels of the Oakland Inner and Outer Harbors to accommodate deeper-draft vessels. The USACE is considering several disposal options for the dredged material removed during these channel improvements including open-water disposal. Dredged material proposed for open-water disposal must be evaluated to determine the potential impacts of the disposal activity on the water column and disposal site environments. The USACE requested that Battelle/Marine Sciences Laboratory (MSL) conduct studies to evaluate open-water disposal options for Oakland Harbor sediments. This request developed into the Oakland Harbor Phase III Program. This is Volume 2 of a two-volume report that presents information gathered to determine the suitability of ocean disposal of sediments dredged from Oakland Harbor. This volume contains the Appendixes (A through N), which provide details of the data analyses and full presentation of the data and results.

  20. Structural damage monitoring of harbor caissons with interlocking condition

    Energy Technology Data Exchange (ETDEWEB)

    Huynh, Thanh Canh; Lee, So Young; Nauyen, Khac Duy; Kim, Jeong Tae [Pukyong National Univ., Busan (Korea, Republic of)

    2012-12-15

    The objective of this study is to monitor the health status of harbor caissons which have potential foundation damage. To obtain the objective, the following approaches are performed. Firstly, a structural damage monitoring(SDM) method is designed for interlocked multiple caisson structures. The SDM method utilizes the change in modal strain energy to monitor the foundation damage in a target caisson unit. Secondly, a finite element model of a caisson system which consists of three caisson units is established to verify the feasibility of the proposed method. In the finite element simulation, the caisson units are constrained each other by shear key connections. The health status of the caisson system against various levels of foundation damage is monitored by measuring relative modal displacements between the adjacent caissons.

  1. Perthes disease: A new finding in Floating-Harbor syndrome.

    Science.gov (United States)

    Milani, Donatella; Scuvera, Giulietta; Gatti, Marta; Tolva, Gianluca; Bonarrigo, Francesca; Esposito, Susanna; Gervasini, Cristina

    2018-01-31

    Floating-Harbor Syndrome (FHS; OMIM #136140) is an ultra-rare autosomal dominant genetic condition characterized by expressive language delay, short stature with delayed bone mineralization, a triangular face with a prominent nose, and deep-set eyes, and hand anomalies. First reported in 1973, FHS is associated with mutations in the SRCAP gene, which encodes SNF2-related CREBBP activator protein. Mutations in the CREBBP gene cause Rubinstein-Taybi Syndrome (RSTS; OMIM #180849, #613684), another rare disease characterized by broad thumbs and halluces, facial dysmorphisms, short stature, and intellectual disability, which has a phenotypic overlap with FHS. We describe a case of FHS associated with a novel SRCAP mutation and characterized by Perthes disease, a skeletal anomaly described in approximately 3% of patients with RSTS. Thus Perthes disease can be added to the list of clinical features that overlap between FHS and RSTS. © 2018 Wiley Periodicals, Inc.

  2. The defining DNA methylation signature of Floating-Harbor Syndrome.

    Science.gov (United States)

    Hood, Rebecca L; Schenkel, Laila C; Nikkel, Sarah M; Ainsworth, Peter J; Pare, Guillaume; Boycott, Kym M; Bulman, Dennis E; Sadikovic, Bekim

    2016-12-09

    Floating-Harbor syndrome (FHS) is an autosomal dominant genetic condition characterized by short stature, delayed osseous maturation, expressive language impairment, and unique facial dysmorphology. We previously identified mutations in the chromatin remodeling protein SRCAP (SNF2-related CBP Activator Protein) as the cause of FHS. SRCAP has multiple roles in chromatin and transcriptional regulation; however, specific epigenetic consequences of SRCAP mutations remain to be described. Using high resolution genome-wide DNA methylation analysis, we identified a unique and highly specific DNA methylation "epi-signature" in the peripheral blood of individuals with FHS. Both hyper and hypomethylated loci are distributed across the genome, preferentially occurring in CpG islands. Clonal bisulfite sequencing of two hypermethylated (FIGN and STPG2) and two hypomethylated (MYO1F and RASIP1) genes confirmed these findings. The identification of a unique methylation signature in FHS provides further insight into the biological function of SRCAP and provides a unique biomarker for this disorder.

  3. Ecological evaluation of proposed dredged material from Richmond Harbor

    Energy Technology Data Exchange (ETDEWEB)

    Pinza, M R; Ward, J A; Mayhew, H L; Word, J Q; Niyogi, D K; Kohn, N P [Battelle/Marine Sciences Lab., Sequim, WA (United States)

    1992-10-01

    During the summer of 1991, Battelle/Marine Sciences Laboratory (MSL) was contracted to conduct sampling and testing of sediments proposed for dredging of Richmond Harbor, California. The MSL collected sediment cores to a depth of [minus]40 ft MLLW ([minus]38 ft + 2 ft overdepth) from 28 (12-in. core) and 30 (4-in. core) stations. The sediment cores were allocated to six composite samples referred to as sediment treatments, which were then subjected to physical, chemical, toxicological, and bioaccumulation testing. Physical and chemical parameters included grain size, total organic carbon (TOC), total volatile solids (TVS), oil and grease, total petroleum hydrocarbons (TPH), polynuclear aromatic hydrocarbons (PAH), chlorinated pesticides, polychlorinated biphenyis (PCBs), priority pollutant metals, and butyltins. The results from the test treatments were compared to results from five reference treatments representative of potential in-bay and offshore disposal sites.

  4. Water level oscillations in Monterey Bay and Harbor

    Directory of Open Access Journals (Sweden)

    J. Park

    2015-06-01

    Full Text Available Seiches are normal modes of water bodies responding to geophysical forcings with potential to significantly impact ecology and maritime operations. Analysis of high-frequency (1 Hz water level data in Monterey, California, identifies harbor modes between 10 and 120 s that are attributed to specific geographic features. It is found that modal amplitude modulation arises from cross-modal interaction and that offshore wave energy is a primary driver of these modes. Synchronous coupling between modes is observed to significantly impact dynamic water levels. At lower frequencies with periods between 15 and 60 min, modes are independent of offshore wave energy, yet are continuously present. This is unexpected since seiches normally dissipate after cessation of the driving force, indicating an unknown forcing. Spectral and kinematic estimates of these low-frequency oscillations support the idea that a persistent anticyclonic mesoscale gyre adjacent to the bay is a potential mode driver, while discounting other sources.

  5. Electrochemical Oxidation of PAHs in Water from Harbor Sediment Purification

    DEFF Research Database (Denmark)

    Muff, Jens; Søgaard, Erik Gydesen

    to contamination by PAH, heavy metals, TBT etc. In Denmark, contaminated harbor sediment is pumped ashore to inland lakes or upland sites where treatment of the runoff water is required before discharge to the recipient. In this study, electrochemical oxidation (EO) has been investigated as a method for treatment...... of the discharge water addressing primarily polycyclic aromatic hydrocarbons (PAHs). PAHs are by-products of incomplete combustion of organic materials with recalcitrant and strong mutagenic/carcinogenic properties, due to their benzene analogue structures. PAHs are hydrophobic compounds and their persistence...... in the environment is mainly due to their low water solubility. The experimental study was performed in laboratory scale with volumes of water from 3 to 10 L in a batch recirculation experimental setup at constant temperature with a commercial one-compartment cell of tubular design with Ti/Pt90-Ir10 anode (60 cm2...

  6. Geographic, seasonal, and diurnal surface behavior of harbor porpoises

    DEFF Research Database (Denmark)

    Teilmann, Jonas; Christiansen, C.T.; Kjellerup, Sanne

    2013-01-01

    are essential information on the status and management of the species. Thirty-five free-ranging harbor porpoises (Phocoena phocoena) were tracked in the region between the Baltic and the North Sea for 25-349 d using Argos satellite transmitters. No differences were found in surface behavior between geographical...... areas or the size of the animals. Slight differences were found between the two sexes and time of day. Surface time peaked in April, where 6% was spent with the transmitter above surface and 61.5% between 0 and 2 m depth, while the minimum values occurred in February (3.4% and 42.5%, respectively......). The analyses reveal that individual variation among porpoises is the most important factor in explaining variation in surface rates. However, the large number of animals documented in the present study covering a wide range of age and sex groups justifies the use of the seasonal average surface times...

  7. Receiving beam patterns in the horizontal plane of a harbor porpoise (Phocoena phocoena)

    NARCIS (Netherlands)

    Kastelein, R.A.; Janssen, M.; Verboom, W.C.; Haan, D. de

    2005-01-01

    Receiving beam patterns of a harbor porpoise were measured in the horizontal plane, using narrow-band frequency modulated signals with center frequencies of 16, 64, and 100 kHz. Total signal duration was 1000 ms, including a 200 ms rise time and 300 ms fall time. The harbor porpoise was trained to

  8. 33 CFR 334.930 - Anaheim Bay Harbor, Calif.; Naval Weapons Station, Seal Beach.

    Science.gov (United States)

    2010-07-01

    ... Weapons Station, Seal Beach. 334.930 Section 334.930 Navigation and Navigable Waters CORPS OF ENGINEERS... Bay Harbor, Calif.; Naval Weapons Station, Seal Beach. (a) The restricted area. The water of Anaheim Bay Harbor between the east and west jetties at the United States Naval Weapons Station, Seal Beach...

  9. High risk of acute deterioration in patients harboring symptomatic colloid cysts of the third ventricle

    NARCIS (Netherlands)

    Hamer, PCD; Verstegen, MJT; De Haan, RJ; Vandertop, P; Thomeer, RTWM; Mooij, JJA; van Furth, WR

    Object. Patients harboring colloid cysts of the third ventricle can present with acute neurological deterioration, or the first indication of the lesion may appear when the patient suddenly dies. The risk of such an occurrence in a patient already identified as harboring a colloid cyst is unknown.

  10. High risk of acute deterioration in patients harboring symptomatic colloid cysts of the third ventricle

    NARCIS (Netherlands)

    de Witt Hamer, Philip C.; Verstegen, Marco J. T.; de Haan, Rob J.; Vandertop, W. Peter; Thomeer, Ralph T. W. M.; Mooij, Jan J. A.; van Furth, Wouter R.

    2002-01-01

    Object. Patients harboring colloid cysts of the third ventricle can present with acute neurological deterioration, or the first indication of the lesion may appear when the patient suddenly dies. The risk of such an occurrence in a patient already identified as harboring a colloid cyst is unknown.

  11. Are federal sustained yield units equitable? A case study of the Grays Harbor unit.

    Science.gov (United States)

    Con H Schallau; Wilbur R. Maki

    1986-01-01

    The Grays Harbor Federal Sustained Yield Unit (U.S. Department of Agriculture, Forest Service) was established in 1949 to enhance the economic stability of the forest products industry and dependent communities in Grays Harbor County, Washington. Provisions of the unit's charter require that all logs harvested from the Quinault Ranger District of the Olympic...

  12. 33 CFR 165.1401 - Apra Harbor, Guam-safety zones.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Apra Harbor, Guam-safety zones... Navigation Areas and Limited Access Areas Fourteenth Coast Guard District § 165.1401 Apra Harbor, Guam—safety zones. (a) The following is designated as Safety Zone A—The waters of the Pacific Ocean and Apra Outer...

  13. 33 CFR 100.118 - Searsport Lobster Boat Races, Searsport Harbor, ME.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Searsport Lobster Boat Races, Searsport Harbor, ME. 100.118 Section 100.118 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Lobster Boat Races, Searsport Harbor, ME. (a) Regulated Area. The regulated area includes all waters of...

  14. 75 FR 53572 - Safety Zone; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA

    Science.gov (United States)

    2010-09-01

    ... [Docket No. USCG-2010-0799] RIN 1625-AA00 Safety Zone; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA... temporary safety zone within the navigation channel in Budd Inlet, WA during Olympia Harbor Days tug boat... boat races. DATES: This rule is effective from 8 a.m. until 8 p.m. on September 5th, 2010. ADDRESSES...

  15. 76 FR 30825 - Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA

    Science.gov (United States)

    2011-05-27

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation; Olympia Harbor Days Tug Boat... boat races. This action is necessary to restrict vessel movement within the specified race area... rulemaking (NPRM) entitled Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA in...

  16. 76 FR 1384 - Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA

    Science.gov (United States)

    2011-01-10

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation; Olympia Harbor Days Tug Boat... annual Olympia Harbor Days tug boat races. This action is necessary to restrict vessel movement within.... Background and Purpose Tug boat races typically result in vessel and spectator congestion in the proximity of...

  17. 76 FR 7701 - Special Local Regulations; Krewe of Charleston Mardi Gras Boat Parade, Charleston Harbor...

    Science.gov (United States)

    2011-02-11

    ... Gras Boat Parade, Charleston Harbor, Charleston, SC AGENCY: Coast Guard, DHS. ACTION: Temporary final... Mardi Gras Boat Parade on the Ashley River and in Charleston Harbor in Charleston, South Carolina. This... Guard did not receive notice of the Krewe of Charleston Mardi Gras Boat Parade with sufficient time to...

  18. Congress Investigates: Pearl Harbor and 9/11 Congressional Hearing Exhibits

    Science.gov (United States)

    Blackerby, Christine

    2011-01-01

    On the morning of December 7, 1941, Japanese bombers staged a surprise attack on U.S. military forces at Pearl Harbor in Hawaii. Sixty years after the attack on Pearl Harbor, the United States was attacked again. On the morning of September 11, 2001, four commercial airplanes hijacked by 19 terrorists killed nearly 3,000 people when they crashed…

  19. 77 FR 31186 - Security Zone; USS MISSISSIPPI Commissioning; Pascagoula Harbor & Pascagoula River; Pascagoula, MS

    Science.gov (United States)

    2012-05-25

    ... Harbor shoreward of the Horn Island Pass Lighted Buoy HI (RW ``HI'' Mo (A); Position 30-08- 30.049 N, 088... MISSISSIPPI is transiting through the harbor and when moored in the Port of Pascagoula. The effect of this..., Federalism, if it has a substantial direct effect on the States, on the relationship between the national...

  20. 33 CFR 110.190 - Tortugas Harbor, in vicinity of Garden Key, Dry Tortugas, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Tortugas Harbor, in vicinity of Garden Key, Dry Tortugas, Fla. 110.190 Section 110.190 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.190 Tortugas Harbor, in vicinity of Garden Key, Dry Tortugas,...

  1. 76 FR 27890 - Special Local Regulations for Marine Events; Severn River, Spa Creek and Annapolis Harbor...

    Science.gov (United States)

    2011-05-13

    ... SECURITY Coast Guard 33 CFR Part 100 Special Local Regulations for Marine Events; Severn River, Spa Creek... Annapolis'' triathlon, a marine event to be held on the waters of Spa Creek and Annapolis Harbor on May 14... Spa Creek and Annapolis Harbor during the event. DATES: This rule is effective from 6 a.m. until 9 a.m...

  2. 33 CFR 110.129a - Apra Harbor, Guam. (Datum: WGS 84)

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. (Datum: WGS 84) 110.129a Section 110.129a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.129a Apra Harbor, Guam. (Datum: WGS 84) (a...

  3. 77 FR 11434 - Safety Zone; Patapsco River, Northwest and Inner Harbors, Baltimore, MD

    Science.gov (United States)

    2012-02-27

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Patapsco River, Northwest and Inner Harbors... proposes to establish a temporary safety zone upon certain waters of the Patapsco River, Northwest Harbor... CONSTELLATION will be towed ``dead ship,'' which means that the vessel will be underway without the benefit of...

  4. Sedimentation and chronology of heavy metal pollution in Oslo harbor, Norway

    DEFF Research Database (Denmark)

    Lepland, Aivo; Andersen, Thorbjørn Joest; Lepland, Aave

    2010-01-01

    indicate that propeller wash affects the seabed in the Oslo harbor. The propeller-induced turbulence causes erosion, and in places exposes and remobilizes contaminated sediments that accumulated in the harbor during previous decades. Such re-exposure of contaminated sediments could be detrimental to local...

  5. 76 FR 20530 - Safety Zone; Boom Days, Buffalo Outer Harbor, Buffalo, NY

    Science.gov (United States)

    2011-04-13

    ... intended to restrict vessels from Doug's Dive, the NFTA small boat harbor and a portion of the Buffalo... celebrate the removal of the ice boom in Lake Erie and the beginning of spring. Establishing a safety zone... waters of the NFTA small boat marina known as Doug's Dive and part of the Buffalo Outer Harbor, Buffalo...

  6. Analyzing Approaches to Internet Jurisdiction Based on Model of Harbors and the High Seas

    NARCIS (Netherlands)

    Jiménez, W.G.; Lodder, A.R.

    2015-01-01

    The inherent cross-border nature of the internet has challenged the legal system for over two decades. In this paper we introduce a model in which the internet is approached as if it were the high seas, the harbor of origin, the harbor of destination, or a combination of these. This model is used to

  7. 77 FR 2493 - Special Local Regulations for Marine Events; Spa Creek and Annapolis Harbor, Annapolis, MD

    Science.gov (United States)

    2012-01-18

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations for Marine Events; Spa Creek... ``TriRock Triathlon Series'', a marine event to be held on the waters of Spa Creek and Annapolis Harbor... portion of the Spa Creek and Annapolis Harbor during the event. DATES: Comments and related material must...

  8. 77 FR 15602 - Special Local Regulations for Marine Events; Spa Creek and Annapolis Harbor, Annapolis, MD

    Science.gov (United States)

    2012-03-16

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations for Marine Events; Spa Creek... Triathlon Series'', a marine event to be held on the waters of Spa Creek and Annapolis Harbor on May 12... the Spa Creek and Annapolis Harbor during the event. DATES: This rule is effective and will be...

  9. 78 FR 20066 - Special Local Regulations; Marine Events, Spa Creek and Annapolis Harbor; Annapolis, MD

    Science.gov (United States)

    2013-04-03

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Marine Events, Spa Creek and...Rock Triathlon Series'', a marine event to be held on the waters of Spa Creek and Annapolis Harbor on... portion of Spa Creek and Annapolis Harbor during the event. ] DATES: Comments and related material must be...

  10. 33 CFR 110.27 - Lynn Harbor in Broad Sound, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lynn Harbor in Broad Sound, Mass. 110.27 Section 110.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.27 Lynn Harbor in Broad Sound, Mass. North of...

  11. 76 FR 70647 - Safety Zone; Fireworks Display, Potomac River, National Harbor Access Channel, MD

    Science.gov (United States)

    2011-11-15

    ... Harbor Access Channel, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast... floating platform located within the National Harbor Access Channel, in Prince Georges County, Maryland... Access Channel, within a 50 yards radius of a fireworks discharge platform in approximate position...

  12. 77 FR 42464 - Special Local Regulations for Marine Events; Potomac River, National Harbor Access Channel, MD

    Science.gov (United States)

    2012-07-19

    ... River, National Harbor Access Channel, MD AGENCY: Coast Guard, DHS. ACTION: Proposed rule; withdrawal... ``Special Local Regulations for Marine Events; Potomac River, National Harbor Access Channel, MD'' in the... Channel, in Prince George's County, MD, effective from 5 a.m. until 11 a.m. on August 5, 2012. The...

  13. 77 FR 20750 - Special Local Regulations for Marine Events; Potomac River, National Harbor Access Channel, MD

    Science.gov (United States)

    2012-04-06

    ... River, National Harbor Access Channel, MD AGENCY: Coast Guard, DHS. ACTION: Notice of proposed... temporarily restrict vessel traffic in a portion of the Potomac River and National Harbor Access Channel... Access Channel from 6 a.m. to 10 a.m. The sponsor has stated that this marine event is not expected to be...

  14. 78 FR 33219 - Special Local Regulations; Swim Across the Potomac, Potomac River; National Harbor Access Channel...

    Science.gov (United States)

    2013-06-04

    ..., Potomac River; National Harbor Access Channel, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule... Access Channel, MD'' in the Federal Register (78 FR 67). We received no comments on the proposed rule. No... the Potomac River and National Harbor Access Channel during the event, the effect of this regulation...

  15. 76 FR 33721 - Takes of Marine Mammals Incidental to Specified Activities; Harbor Activities Related to the...

    Science.gov (United States)

    2011-06-09

    ... Small Haul-out Site 1 to flush into VAFB Harbor or to cause a short-term behavioral disturbance for... Missile Center (WSMC) in the Pacific Ocean (33 CFR 334.1130(a)(2)(vi)), ULA requires that the harbor...) states that the estimated population of the U.S. stock of California sea lion ranged from 141,842 to 238...

  16. 75 FR 43823 - Safety Zone; He'eia Kea Small Boat Harbor, Kaneohe Bay, Oahu, HI

    Science.gov (United States)

    2010-07-27

    ..., Oahu, HI AGENCY: Coast Guard, DHS. ACTION: Temporary Final Rule. SUMMARY: The Coast Guard is establishing a temporary safety zone in He'eia Kea Small Boat Harbor located in Kaneohe Bay, Oahu, Hawaii. The... Small Boat Harbor located in Kaneohe Bay, Oahu, Hawaii. This safety zone is in the shape of a box...

  17. POLLUTION ASSESSMENT IN DREDGING SEDIMENT FROM HARBOR AREAS OF THE CIENFUEGOS BAY (CUBA

    Directory of Open Access Journals (Sweden)

    Anabell Pulido Caraballé

    2016-04-01

    Full Text Available The characterization of the dredging sediments is essential for environmental license, control and planning in dredging harbors. Sediment pollution was study in two harbor areas of the Cienfuegos Bay. Dredging sediments from “Camilo Cienfuegos” Refinery port and from area IX of Cienfuegos harbor were characterized. In order to evaluate dredging sediment quality, an analysis of water content, grain size, organic matter and trace metals was done. The results show that the trace elements in the sediments are at natural levels. Due to the absent of Cuban rules for these topics, international criteria for sampling, analysis and sediment quality evaluation were used in the study. Results show that these levels can be considered as typical for harbor areas in which authorization for dredging activities in docks and navigation channel should be granted. The results and methodologies will be applied in others Cuban harbors and navigation channel during the environmental license of dredging sediments.

  18. Tsunami Hazard Assessment in New Zealand Ports and Harbors

    Science.gov (United States)

    Borrero, J. C.; Wotherspoon, L.; Power, W. L.; Goring, D.; Barberopoulou, A.; Melville, B.; Shamseldin, A.

    2012-12-01

    The New Zealand Ministry of Science and Innovation (MSI) has sponsored a 3-year collaborative project involving industry, government and university research groups to better assess and prepare for tsunami hazards in New Zealand ports and harbors. As an island nation, New Zealand is highly dependent on its maritime infrastructure for commercial and recreational interests. The recent tsunamis of 2009, 2010 and 2011 (Samoa, Chile and Japan) highlighted the vulnerability of New Zealand's marine infrastructure to strong currents generated by such far field events. These events also illustrated the extended duration of the effects from such tsunamis, with some of the strongest currents and highest water levels occurring many hours, if not days after the tsunami first arrival. In addition, New Zealand also sits astride the Tonga-Kermadec subduction zone, which given the events of recent years, cannot be underestimated as a major near field hazard. This presentation will discuss the modeling and research strategy that will be used to mitigate tsunami hazards in New Zealand ports and harbors. This will include a detailed time-series analysis (including Fourier and discrete Wavelet techniques) of water levels recorded throughout New Zealand form recent tsunami events (2009 Samoa, 2010 Chile and 2011 Japan). The information learned from these studies will guide detailed numerical modeling of tsunami induced currents at key New Zealand ports. The model results will then be used to guide a structural analysis of the relevant port structures in terms of hydrodynamic loads as well as mooring and impact loads due to vessel and/or debris. Ultimately the project will lead to an improvement in New Zealand's tsunami response plans by providing a decision making flow chart, targeted for marine facilities, to be used by emergency management officials during future tsunami events.Tsunami effects at Port Charles, New Zealand: (top) inundation into a neighborhood and (bottom left and right

  19. Abstracts of papers presented at the LVIII Cold Spring Harbor Symposium on quantitative Biology: DNA and chromosomes

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-31

    This volume contains the abstracts of oral and poster presentations made at the LVIII Cold Spring Harbor Symposium on Quantitative Biology entitles DNA & Chromosomes. The meeting was held June 2--June 9, 1993 at Cold Spring Harbor, New York.

  20. Strategies for Overcoming Resistance in Tumours Harboring BRAF Mutations

    Directory of Open Access Journals (Sweden)

    Nourah Mohammad Obaid

    2017-03-01

    Full Text Available The development of resistance to previously effective treatments has been a challenge for health care providers and a fear for patients undergoing cancer therapy. This is an unfortunately frequent occurrence for patients undergoing targeted therapy for tumours harboring the activating V600E mutation of the BRAF gene. Since the initial identification of the BRAF mutation in 2002, a series of small molecular inhibitors that target the BRAFV600E have been developed, but intrinsic and acquired resistance to these drugs has presented an ongoing challenge. More recently, improvements in therapy have been achieved by combining the use of BRAF inhibitors with other drugs, such as inhibitors of the downstream effector mitogen activated protein kinase (MAPK/extracellular-signal regulated kinase (ERK kinase (MEK. Despite improved success in response rates and in delaying resistance using combination therapy, ultimately, the acquisition of resistance remains a concern. Recent research articles have shed light on some of the underlying mechanisms of this resistance and have proposed numerous strategies that might be employed to overcome or avoid resistance to targeted therapies. This review will explore some of the resistance mechanisms, compare what is known in melanoma cancer to colorectal cancer, and discuss strategies under development to manage the development of resistance.

  1. Synanthropic Cockroaches (Blattidae: Periplaneta spp.) Harbor Pathogenic Leptospira in Colombia.

    Science.gov (United States)

    Gonzalez-Astudillo, Viviana; Bustamante-Rengifo, Javier A; Bonilla, Álvaro; Lehmicke, Anna Joy J; Castillo, Andrés; Astudillo-Hernández, Miryam

    2016-01-01

    Leptospirosis cases in Colombia are typically linked to peridomestic rodents; however, empirical data suggest that Leptospira-infected patients with no apparent exposure to these reservoirs are common. Cockroaches (Periplaneta spp.) have equal or greater interaction with humans than rodents, yet their potential role as carriers of Leptospira has not been assessed. We determined if pathogenic Leptospira is harbored by Periplaneta spp. in Cali (Colombia) and the variables influencing this relationship. Fifty-nine cockroaches were captured from seven sites and DNA was extracted from the body surface and digestive tract for a multiplex polymerase chain reaction, targeting genes secY and flaB. Logistic regression models and proportion tests showed a higher likelihood for Leptospira to be isolated from body surfaces (P > 0.001) and from individuals inside houses (six times more likely). These findings are the first to demonstrate an association between Periplaneta spp. and Leptospira, suggesting the need to investigate the potential for cockroaches to serve as reservoirs or transport hosts for Leptospira. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Evaluation of older bay mud sediment from Richmond Harbor, California

    Energy Technology Data Exchange (ETDEWEB)

    Pinza, M.R.; Mayhew, H.L.; Word, J.Q.

    1996-09-01

    The older, bay mud (OBM) unit predates modem man and could act as a barrier to the downward transport of contaminants from the younger bay mud (YBM) because of its hard-packed consistency. However, its chemical and biological nature have not been well characterized. Battelle/Marine Sciences Laboratory (MSL) conducted three independent studies of OBM sediment in January 1993, January 1994, and October 1994. These studies evaluated potential chemical contamination and biological effects of OBM that could occur as a result of dredging and disposal activities. These evaluations were performed by conducting chemical analysis, solid-phase toxicity tests, suspended- particulate-phase (SPP) toxicity tests, and bioaccumulation tests on the OBM sediment. If the sediment chemistry and toxicity results showed no or minimal contamination and toxicological responses, then either the OBM could be left exposed in Richmond Harbor after dredging the YBM without leaving a source of contamination, or if the project depths necessitate, the OBM would be acceptable for disposal at an appropriate disposal site.

  3. Precocious puberty in a girl with floating-harbor syndrome.

    Science.gov (United States)

    Stagi, Stefano; Galluzzi, Fiorella; Bindi, Giuseppe; Lapi, Elisabetta; Cecchi, Cecilia; Salti, Roberto; Chiarelli, Francesco

    2007-12-01

    Floating-Harbor syndrome (FHS) is a rare genetic disorder characterized by short stature, delayed bone age, mild to moderate mental retardation, speech problems, and peculiar craniofacial features. In these patients pubertal development has been reported to be normal. In this paper, we describe a girl with FHS who developed precocious puberty. FHS diagnosis was made at 2 years 5 months on the basis of peculiar clinical features. At 7 years 7 months, the girl began pubertal development; her height was 112.5 cm (-2.42 SDS) and pubertal staging was B2 PH2 AH1. LHRH test underlined LH and FSH peak values of 11.7 mIU/ml and 6.2 mIU/ml, respectively. Plasma levels of 17beta-estradiol were normal (8.5 pg/ml). Ophthalmological and neurological examinations, including nuclear magnetic resonance imaging of the brain, were normal. Treatment with gonadotrophin-releasing hormone analogue was begun. At 10 years 1 month, because of reduced height velocity, her growth hormone secretion was evaluated with diagnosis of neurosecretory dysfunction; hGH therapy was begun. The patient showed a good response to hGH treatment, reaching a normal adult height (156.1 cm; -1.20 SDS). This report suggests that, in patients with FHS, precocious puberty should be taken into consideration; in these patients, a careful endocrinological followup for the possible presence of growth and pubertal disorders is needed.

  4. The phenotype of Floating-Harbor syndrome in 10 patients.

    Science.gov (United States)

    White, Susan M; Morgan, Angela; Da Costa, Annette; Lacombe, Didier; Knight, Samantha J L; Houlston, Richard; Whiteford, Margo L; Newbury-Ecob, Ruth A; Hurst, Jane A

    2010-04-01

    Floating-Harbor syndrome (FHS) is a rare condition typified by short stature, speech impairment, delayed bone age, and characteristic facies. The diagnosis can be difficult as the facial changes are subtle in infancy, and the features of short stature, delayed speech, and delayed bone age are frequently encountered in clinical practice. We refine the phenotype in FHS by reporting clinical findings in 10 typically affected individuals ranging in age from 7 to 34 years and present a mother and daughter who display some features of FHS. Bone age measurements were delayed when measured from age 6 months to 6 years but in some patients were normal between 6 and 12 years. Dysmorphic features at different ages are characterized. The lateral profile of the face and the characteristic body habitus aided diagnosis. Significant behavioral problems of hyperactivity, short attention span and aggression during childhood were reported for most individuals. The children studied had a severe and incapacitating disorder of speech and language. Intellectual functioning ranged from borderline normal to moderate intellectual disability. Early puberty was noted. Adult heights were 140-155 cm. Microarray analysis in eight of the patients provided no evidence that FHS is caused by a large-scale copy-number genomic change. (c) 2010 Wiley-Liss, Inc.

  5. Imposex reduction and residual butyltin contamination in southern Brazilian harbors.

    Science.gov (United States)

    Castro, Ítalo Braga; Rossato, Martina; Fillmann, Gilberto

    2012-05-01

    The imposex incidence was appraised in South American gastropods, considering the scenario before and after the global ban of tributyltin (TBT). A statistically significant reduction in imposex indexes was observed in Stramonita haemastoma collected in 2006 and 2010 from areas under the influence of four coastal harbors from southern Brazil. This reduction may be because of the effectiveness of the global ban issued by the International Maritime Organization, although the restrictions on TBT-based antifouling paints in Brazil might also have helped. Even so, a residual organotin contamination was still detected in female tissues (levels ranged from 7.6 to 164.9 ng Sn/g for TBT; from imposex and environmental levels of organotins is expected in every ocean worldwide soon after the implementation of national and international restriction regulations, this will depend on the effectiveness of the global TBT ban; the effectiveness of local restrictions on producing, selling, and using TBT-based antifouling paints; and specific characteristics of local sediments, because metabolization rates and sorption/desorption of TBT previously deposited might affect its environmental bioavailability. Therefore, the reduction trend detected in the present study cannot be extrapolated to other Brazilian or South American coastal areas. Copyright © 2012 SETAC.

  6. Harbor seals (Phoca vitulina can perceive optic flow under water.

    Directory of Open Access Journals (Sweden)

    Nele Gläser

    Full Text Available Optic flow, the pattern of apparent motion elicited on the retina during movement, has been demonstrated to be widely used by animals living in the aerial habitat, whereas underwater optic flow has not been intensively studied so far. However optic flow would also provide aquatic animals with valuable information about their own movement relative to the environment; even under conditions in which vision is generally thought to be drastically impaired, e. g. in turbid waters. Here, we tested underwater optic flow perception for the first time in a semi-aquatic mammal, the harbor seal, by simulating a forward movement on a straight path through a cloud of dots on an underwater projection. The translatory motion pattern expanded radially out of a singular point along the direction of heading, the focus of expansion. We assessed the seal's accuracy in determining the simulated heading in a task, in which the seal had to judge whether a cross superimposed on the flow field was deviating from or congruent with the actual focus of expansion. The seal perceived optic flow and determined deviations from the simulated heading with a threshold of 0.6 deg of visual angle. Optic flow is thus a source of information seals, fish and most likely aquatic species in general may rely on for e. g. controlling locomotion and orientation under water. This leads to the notion that optic flow seems to be a tool universally used by any moving organism possessing eyes.

  7. Spatially Estimating Disturbance of Harbor Seals (Phoca vitulina.

    Directory of Open Access Journals (Sweden)

    John K Jansen

    Full Text Available Tidewater glacial fjords in Alaska provide habitat for some of the largest aggregations of harbor seals (Phoca vitulina, with calved ice serving as platforms for birthing and nursing pups, molting, and resting. These fjords have also been popular destinations for tour ships for more than a century, with dramatic increases in vessel traffic since the 1980s. Seals on ice are known to flush into the water when approached by tour ships, but estimating the exposure to disturbance across populations is difficult. Using aerial transect sampling while simultaneously tracking vessel movements, we estimated the spatial overlap between seals on ice and cruise ships in Disenchantment Bay, Alaska, USA. By integrating previously estimated rates of disturbance as a function of distance with an 'intensity surface' modeled spatially from seal locations in the surveys, we calculated probabilities of seals flushing during three separate ship visits. By combining our estimate of seals flushed with a modeled estimate of the total fjord population, we predict that up to 14% of the seals (up to 11% of pups hauled out would have flushed into the water, depending on the route taken by ships relative to seal aggregations. Such high potential for broad-scale disturbance by single vessels (when up to 4 ships visit per day was unexpected and underscores the need to 1 better understand long-term effects of disturbance; 2 regularly monitor populations exposed to high vessel traffic; and 3 develop conservation measures to reduce seal-ship overlap.

  8. Green tide development associated with submarine groundwater discharge in a coastal harbor, Jeju, Korea.

    Science.gov (United States)

    Kwon, Hyeong Kyu; Kang, Hyekyung; Oh, Yong Hwa; Park, Sang Rul; Kim, Guebuem

    2017-07-24

    We measured the magnitude of submarine fresh groundwater discharge (SFGD) and associated nutrient inputs to Jocheon harbor, on Jeju Island, Korea, during four sampling periods, in order to determine the link between SFGD and Ulva sp. green tide development. Good correlations among salinity, 222Rn, and dissolved inorganic nitrogen (DIN) in harbor seawater suggest that SFGD is the major source of DIN and fresh water since there are no surface runoffs. Using a 222Rn mass balance model, SFGD to the harbor was estimated to be 5.8 ± 2.3 × 104 m3 d-1. The DIN inputs through SFGD enhanced DIN concentrations in harbor seawater approximately 10-fold of those in the open-ocean (outer harbor) seawater. Results from mesocosm experiments showed that the growth rate of U. pertusa increased by 160% on average due to the enhanced DIN concentrations (from 1 to 24 µM) through SFGD in this harbor. Thus, we conclude that DIN inputs through SFGD cause the green tide development in Jocheon harbor and perhaps in other green tide regions where river inputs are absent.

  9. 77 FR 36394 - Safety Zone for Fireworks Display, Potomac River, National Harbor Access Channel; Oxon Hill, MD

    Science.gov (United States)

    2012-06-19

    ..., National Harbor Access Channel; Oxon Hill, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule... launched from a floating platform located within the National Harbor Access Channel at Oxon Hill in Prince... River, National Harbor Access Channel, within a 150 yards radius of a fireworks discharge platform in...

  10. 77 FR 56115 - Safety Zone for Fireworks Display, Potomac River, National Harbor Access Channel; Oxon Hill, MD

    Science.gov (United States)

    2012-09-12

    ..., National Harbor Access Channel; Oxon Hill, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule... launched from a floating platform located within the National Harbor Access Channel at Oxon Hill in Prince... Potomac River, National Harbor Access Channel, within a 150 yards radius of a fireworks discharge platform...

  11. 33 CFR 165.T14-204 - Safety Zone; fixed mooring balls, south of Barbers Pt Harbor Channel, Oahu, Hawaii.

    Science.gov (United States)

    2010-07-01

    ..., south of Barbers Pt Harbor Channel, Oahu, Hawaii. 165.T14-204 Section 165.T14-204 Navigation and... Pt Harbor Channel, Oahu, Hawaii. (a) Location. The following area is a safety zone: All waters... position is approximately 2,500 yards south of Barbers Point Harbor channel buoy #2, Oahu, Hawaii. This...

  12. Free living and plankton-associated vibrios: assessment in ballast water, harbor areas and coastal ecosystems in Brazil

    Directory of Open Access Journals (Sweden)

    Irma Nelly G. Rivera

    2013-01-01

    Full Text Available Ballast water is a major transport vector of exotic aquatic species and pathogenic microorganisms. The wide-ranging spread of toxigenic Vibrio cholerae O1 from harbor areas has been frequently ascribed to discharge of contaminated ballast water into eutrophic coastal environments, such as during the onset of the seventh cholera pandemic in South America in the early 1990s. To determine the microbiological hazards of ballast waters transported to Brazilian ports, we evaluated water and plankton samples taken from (i ballast water tanks of recently arrived ships, (ii port areas along the Brazilian coastline from ~1 to 32 oS and (iii three coastal areas in São Paulo State. Vibrio concentration and toxigenic V. cholerae O1 occurrence were analyzed. Plankton-associated vibrios were more abundant than free-living vibrios in all studied environments. Vibrio cholerae was found in 9.5% of ballast tanks and 24.2% of port samples, both as free-living and attached forms, and was absent off São Paulo State. Toxigenic V. cholerae O1 isolates (ctxA+, tcpA+, involved in cholera disease, were found in ballast water (2% and harbor (2% samples. These results confirm that ballast water is an important carrier of pathogenic organisms, and that monitoring of vibrios and other plankton-attached bacteria is of paramount importance in ballast water management programs.

  13. Discrete event simulation for petroleum transfers involving harbors, refineries and pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Marcella S.R.; Lueders, Ricardo; Delgado, Myriam R.B.S. [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil)

    2009-07-01

    Nowadays a great effort has been spent by companies to improve their logistics in terms of programming of events that affect production and distribution of products. In this case, simulation can be a valuable tool for evaluating different behaviors. The objective of this work is to build a discrete event simulation model for scheduling of operational activities in complexes containing one harbor and two refineries interconnected by a pipeline infrastructure. The model was developed in Arena package, based on three sub-models that control pier allocation, loading of tanks, and transfers to refineries through pipelines. Preliminary results obtained for a given control policy, show that profit can be calculated by taking into account many parameters such as oil costs on ships, pier using, over-stay of ships and interface costs. Such problem has already been considered in the literature but using different strategies. All these factors should be considered in a real-world operation where decision making tools are necessary to obtain high returns. (author)

  14. Behavioral effects of environmental enrichment on harbor seals (Phoca vitulina concolor) and gray seals (Halichoerus grypus)

    Science.gov (United States)

    Hunter, S.A.; Bay, M.S.; Martin, M.L.; Hatfield, J.S.

    2002-01-01

    Zoos and aquariums have been incorporating environmental enrichment into their animal care programs for the past 30 years to increase mental stimulation and promote natural behaviors. However, most attempts to document the effects of enrichment on animal behavior have focused on terrestrial mammals. Staff at the National Aquarium in Baltimore conducted an investigation of the behavioral effects of enrichment on the seven harbor seals and two gray seals housed in the aquarium's outdoor seal exhibit. We expected that enrichment would change the amount of time the animals spent engaged in specific behaviors. The behaviors recorded were: resting in water, resting hauled out, maintenance, breeding display, breeding behavior, aggression, pattern swimming, random swimming, exploration, and out of sight. Activity levels (random swimming and exploration) were expected to increase, while stereotypic behaviors (pattern swimming) were expected to decrease. The frequency and duration of behaviors were documented for 90 hr in both the control phase (without enrichment) and the experimental phase (with enrichment). Statistically significant differences (P captivity. ?? 2002 Wiley-Liss, Inc.

  15. Behavioral effects of environmental enrichment on harbor seals (Phoca vitulina concolor) and gray seals (Hafichoerus grypus)

    Science.gov (United States)

    Hunter, S.A.; Bay, M.S.; Martin, M.L.; Hatfield, J.S.

    2002-01-01

    Zoos and aquariums have been incorporating environmental enrichment into their animal care programs for the past 30 years to increase mental stimulation and promote natural behaviors. However, most attempts to document the effects of enrichment on animal behavior have focused on terrestrial mammals. Staff at the National Aquarium in Baltimore conducted an investigation of the behavioral effects of enrichment on the seven harbor seals and two gray seals housed in the aquarium's outdoor seal exhibit. We expected that enrichment would change the amount of time the animals spent engaged in specific behaviors. The behaviors recorded were: resting in water, resting hauled out, maintenance, breeding display, breeding behavior, aggression, pattern swimming, random swimming, exploration, and out of sight. Activity levels (random swimming and exploration) were expected to increase, while stereotypic behaviors (pattern swimming) were expected to decrease. The frequency and duration of behaviors were documented for 90 hr in both the control phase (without enrichment) and the experimental phase (with enrichment). Statistically significant differences (Pcaptivity.

  16. Response to PD-1 Blockade in Microsatellite Stable Metastatic Colorectal Cancer Harboring a POLE Mutation.

    Science.gov (United States)

    Gong, Jun; Wang, Chongkai; Lee, Peter P; Chu, Peiguo; Fakih, Marwan

    2017-02-01

    Recent clinical evidence has demonstrated that microsatellite instability (MSI) or defective mismatch repair (MMR) and high tumor mutational load can predict response to the programmed cell death 1 (PD-1) receptor inhibitor pembrolizumab in metastatic colorectal cancer (mCRC). Mutations in polymerase ε (POLE), a DNA polymerase involved in DNA replication and repair, contribute to an ultramutated but microsatellite stable (MSS) phenotype in colorectal tumors that is uniquely distinct from MSI tumors. This report presents the first case in the literature describing a clinical response to pembrolizumab in an 81-year-old man with treatment-refractory mCRC characterized by an MSS phenotype and POLE mutation identified on genomic profiling by next-generation sequencing. On tumor immunostaining, a large amount of CD8-positive tumor infiltrating lymphocytes (TILs) were present, with >90% of these expressing PD-1. More than 99% of PD-L1 expression was identified on nontumor cells in the tumor microenvironment that were close to the PD-1-positive CD8 TILs. mCRC tumors harboring POLE mutations represent a hypermutated phenotype that may predict response to anti-PD-1 therapy. Copyright © 2017 by the National Comprehensive Cancer Network.

  17. Temporal and spatial variation in harbor seal (Phoca vitulina L.) roar calls from southern Scandinavia

    DEFF Research Database (Denmark)

    Sabinsky, Puk Faxe; Larsen, Ole Næsbye; Wahlberg, Magnus

    2017-01-01

    Male harbor seals gather around breeding sites for competitive mating displays. Here, they produce underwater vocalizations possibly to attract females and/or scare off other males. These calls offer prospects for passive acoustic monitoring. Acoustic monitoring requires a good understanding...... of natural variation in calling behavior both temporally and among geographically separate sites. Such variation in call structure and calling patterns were studied in harbor seal vocalizations recorded at three locations in Danish and Swedish waters. There was a strong seasonality in the calls from end...... biological differences when comparing harbor seal roars among recording sites and between years....

  18. Why aircraft will fly more fuel-efficiently on FRIDAY : The FRIDAY route charges method

    NARCIS (Netherlands)

    Verbeek, R.J.D.; Visser, H.G.; Lovell, D.; Fricke, H.

    2016-01-01

    The Single European Sky is being introduced to improve the efficiency of flight and traffic operations by reforming the air traffic management system. Despite all of these technical advances, airlines choose detours to avoid high route charges. This mechanism is intensified when fuel prices are low.

  19. Resonance interaction between Bays and Harbors forced by tsunamis

    Science.gov (United States)

    Vela, Jordi; Pérez, Begoña.; González, Mauricio; Otero, Luis; Olabarrieta, Maitane; Canals, Miquel

    2010-05-01

    The tsunami induced by the 21 May 2003 Boumerdès-Zemmouri (Algeria) earthquake (Mw=6.9) did not generated important inundations damages or fatalities in the western Mediterranean area. However, damages and economic losses were reported in some harbors, generated by important sea level disturbances. Noticeable impacts were noted (broken mooring lines, sunken boats, displaced moorings, etc.) in some harbours in the Balearic Islands (Palma de Majorca, Ibiza and San Antoni) and also along the French border (La Figueirette and Mouré-Rouge harbours). Various authors have attempted to simulate this event finding discrepancies between the tsunami arrival time and amplitudes of waves on the tide gauges and results with numerical models. The models underestimate the amplitude of the tsunami. In some cases the underestimations have been associated to numerical limitations due to the lack of a high-resolution bathymetry and poor harbor geometry definition. Other cases, associated to a non appropriate seismic source characterization. Finally, some authors point out the occurrence of one or several submarine landslides triggered by the earthquake simultaneously with the seafloor vertical displacement, which have not been included in the numerical simulations. For a better knowledge of the response of a harbour interacting with a bay forced by a tsunami, a numerical study has been carried out for Palma Bay and Palma de Majorca Harbour. The transference of energy of the tsunami from the generation area to the continental shelf, the bay and the harbour has been studied for the Algerian tsunami (21 May 2003) and compared with the natural oscillation modes of the bay and the harbour water bodies. Furthermore, a sensibility analysis regarding the influence of the grid size of the harbour and bay bathymetries was also performed to understand the discrepancies between simulations and observations. The 2003 Zemmouri tsunami measured by the tidal gauge of Palma habour showed energy

  20. Mnemiopsis leidyi Gut Harbors Seasonally Variant and Commensal Microbial Assemblages

    Science.gov (United States)

    Mariita, R. M.; Hossain, M. J.; Liles, M. R.; Moss, A.

    2016-02-01

    Studies have shown that with widespread use of antibiotics in human and domestic animal populations, antibiotic resistance becomes increasingly common in the environment. Estuaries provide ideal conditions for acquisition and dissemination of drug resistance genes because they serve as sinks for pollution. This study aimed to identify M. leidyi microbial diversity and richness and their potential to act as vectors for antibiotic resistance determinants (ARDs). M. leidyi, although native to study area are highly invasive. Metagenomic analyses indicate that there are temporal variations of bacterioplankton assemblages in M. leidyi gut. Overall, Proteobacteria and Actinobacteria are the most abundant phyla. Despite the temporal dynamics in the microbial assemblages in M. leidyi gut, they seem to retain Propionibacterium acnes (gut microbiota in some insects) and select proteobacteria across all seasons. The results contradict previous studies that suggest that M. leidyi does not have constant a microbiota, but only seasonally variant microbial assemblages. Here we reveal the presence of M. leidyi gut ARDs in winter and summer, probably because of the ctenophores' positive geotaxis during rough surface conditions. Genes responsible for resistance to fluoroquinolones, multidrug resistance efflux pumps, mercuric reductase, copper homeostasis and blaR1 genes were observed. This is the first study to demonstrate that M. leidyi harbors constant microbiota and provides a baseline for understanding M. leidyi gut microbial and ARDs ecology. It also suggests that M. leidyi bacterial taxonomic and functional dynamics is influenced by season. Funding: Alabama EPSCoR GRSP fellowship, AU-CMB fellowship, NSF EPS-1158862, USDA-Hatch 370225-310100 (AGM, ML).

  1. Settlement of the USS Arizona, Pearl Harbor, Hawaii

    Science.gov (United States)

    Carkin, Brad A.; Kayen, Robert E.

    2013-01-01

    The U.S. Geological Survey, in collaboration with the National Park Service Submerged Resources Center, undertook investigations at the USS Arizona Memorial at Pearl Harbor, Hawaii, in 2002, 2003, and 2005 to characterize geological factors affecting the deterioration and movement of the hull of the USS Arizona. Since sinking on the morning of December 7, 1941, the hull of the USS Arizona has been slowly but steadily disappearing below the surface of Pearl Harbor. Continuous sediment coring at three of four locations around the hull of the Arizona was only partially successful, but it was sufficient to identify a varied sedimentary substrate beneath the hull. A boring near the stern reveals a thick, continuous sequence of soft, gray clay to the bottom of the boring. In contrast, borings near the bow and starboard side, below about 5 meters subbottom depth, indicate the presence of very stiff, brown clay and coral debris and an absence of soft clay. Multisensor core logger scanning of the recovered cores distinguishes the lower density of the soft, gray clay at the stern from the higher density of the stiff, brown clays and coral debris at the bow and starboard side. Uniaxial consolidation testing of the soft gray clay indicates a normally consolidated sequence, whereas the stiff, brown clay and coral debris are overconsolidated. Profiles of shear wave velocity vs. depth obtained through spectral analysis of interface wave testing around the perimeter of the hull in 2005 identified areas of higher velocity, stiffer sediment at the bow and starboard side, which correspond to the dense, stiff clay recovered near the bow and starboard borings. Low shear-wave velocities at the port midship and quarter of the hull correlate with the lower density, softer sediment recovered from the boring at the stern. Cross sections of the subbottom of the Memorial combine results from the sediment borings and geophysical surveys and depict a wedge of soft clay unconformably overlying

  2. AFSC/ABL: Glacier Bay Harbor Seal Survey, 2004-2007

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The acoustic data collected in Glacier bay from 2005 2007 was used to study the link between marine predator (harbor seals) diving behavior to local prey fields in...

  3. Critical wildlife areas in Port Etches and Constantine Harbor, Hinchinbrook Island, Prince William Sound

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report documents critical wildlife areas in Port Etches and Constantine Harbor, Hinchinbrook Islands, and Prince William Sound during the 1976 and 1977....

  4. Inshore Survey Results: Approaches to New York Harbor, Fall 1955 (NODC Accession 7000294)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A current survey in the approaches to New York Harbor was initiated 06 September 1955 and continued through 04 November 1955. This survey was conducted in accordance...

  5. Multidirectional random wave diffraction in a real harbor by using 3-D boundary element method

    Science.gov (United States)

    Kumar, Prashant; Gulshan, Rajni

    2017-10-01

    The mathematical model is constructed based on 3-D Boundary Element Method (BEM) with the consideration of diffraction, reflection and refraction of multidirectional incident waves utilizing the Laplace equation in a complex geometry harbors. The geometry of the harbor is divided into bounded and open sea region. The partial reflection boundary with variable bathymetry is also considered to analyze the wave spectrum. A Mitsuyasu's wave spectrum is applied to estimate the wave spectrum with multidirectional incident waves. The current numerical approach is practically applied on realistic Pohang New Harbor (PNH), Pohang South Korea. The validation of numerical scheme is done by comparison of measurement data with simulation results at different port stations. Therefore, the current numerical approach is provide the efficient numerical tool to foster the prediction of wave-induced oscillation in a harbor with irregular geometry.

  6. Gridded multibeam bathymetry of Apra Harbor, Guam U.S. Territory

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gridded bathymetry from Apra Harbor, Guam U.S. Territory. The netCDF and Arc ASCII grids include multibeam bathymetry from the Reson SeaBat 8125 multibeam sonar...

  7. Aerial Survey Effort for Harbor Seals in Coastal Alaska (2004-2015)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The most feasible approach to determining harbor seal distribution and abundance in Alaska coastal habitats is to use aircraft to count seals when they haul out of...

  8. The Floating-Harbor syndrome: report of another patient and differential diagnosis with Shprintzen syndrome.

    Science.gov (United States)

    Smeets, E; Fryns, J P; Van den Berghe, H

    1996-01-01

    In this report we describe the typical clinical signs and symptoms in a young female child with Floating-Harbor syndrome. A review of the literature is presented and the differential diagnosis with Shprintzen syndrome is discussed.

  9. 75 FR 5907 - Safety Zone; Dive Platform, Pago Pago Harbor, American Samoa

    Science.gov (United States)

    2010-02-05

    ... Purpose On October 7, 1949 the 4,130-ton gasoline tanker CHEHALIS sank in Pago Pago Inner Harbor, in an... procedures; and related management systems practices) that are developed or adopted by voluntary consensus...

  10. Wave Climate and Wave Response, Kawaihae Deep Draft Harbor, Island of Hawaii, Hawaii

    National Research Council Canada - National Science Library

    Thompson, Edward F; Demirbilek, Zeki; Briggs, Michael J

    2006-01-01

    Present and projected commercial activities in Kawaihae Deep Draft Harbor, Island of Hawaii, HI, indicate that a deeper basin and entrance channel and better protected berthing areas will be needed. The U.S...

  11. 75 FR 39632 - Regulated Navigation Area; Gulf Intracoastal Waterway, Inner Harbor Navigation Canal, Harvey...

    Science.gov (United States)

    2010-07-12

    ..., Inner Harbor Navigation Canal, Harvey Canal, Algiers Canal, New Orleans, LA; Correction ACTION: Interim... Navigation Canal, Harvey Canal, Algiers Canal, New Orleans, LA into the Code of Federal Regulations. That...

  12. Aerial Survey Trend Counts of Harbor Seals in Coastal Alaska (1984-2006) - ADF&G

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Aerial surveys were conducted during 1983–2006 in the Ketchikan, Sitka, Kodiak, and Bristol Bay areas of Alaska to estimate trends in abundance of harbor seals.

  13. A Dataset of Aerial Survey Counts of Harbor Seals in Iliamna Lake, Alaska: 1984-2013

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset provides counts of harbor seals from aerial surveys over Iliamna Lake, Alaska, USA. The data have been collated from three previously published sources...

  14. Environmental Assessment for Waterfront Facilities Maintenance and Improvements, Pearl Harbor Naval Complex, Oahu, Hawaii

    National Research Council Canada - National Science Library

    2005-01-01

    Commander, Navy Region Hawaii (CNRH) proposes to repair, maintain, and improve waterfront berthing and maintenance facilities for ships and submarines on an as-needed basis within the Pearl Harbor Naval Complex (PHNC...

  15. Aerial Survey Counts of Harbor Seals in Lake Iliamna, Alaska, 1984-2013 (NODC Accession 0123188)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset provides counts of harbor seals from aerial surveys over Lake Iliamna, Alaska, USA. The data have been collated from three previously published sources...

  16. Caffeine in Boston Harbor past and present, assessing its utility as a tracer of wastewater contamination in an urban estuary.

    Science.gov (United States)

    Cantwell, Mark G; Katz, David R; Sullivan, Julia C; Borci, Todd; Chen, Robert F

    2016-07-15

    Sites throughout Boston Harbor were analyzed for caffeine to assess its utility as a tracer in identifying sources of sanitary wastewater. Caffeine ranged from 15ng/L in the outer harbor to a high of 185ng/L in the inner harbor. Inner harbor concentrations were a result of combined sewage overflow (CSO) events as well as illicit discharge of sanitary sewage into municipal storm drains. Comparing current results to data from 1998 to 1999 shows reductions in caffeine levels. Reductions are attributed to termination of effluent discharge to the harbor, declines in the number of CSOs and discharge volume along with efforts to eliminate illicit discharges. Spatial distributions of caffeine identified CSOs as major contemporary sources to the inner harbor. The findings further establish the utility of caffeine as a tracer for sanitary wastewater contamination in urban estuaries and demonstrate the efficacy of pollution reduction strategies undertaken in recent decades in Boston Harbor. Published by Elsevier Ltd.

  17. Waking the Sleeping Giant at Pearl Harbor: A Case for Intelligence and Operations Fusion

    Science.gov (United States)

    2013-05-23

    learned of Japan’s initial attack plans.147 A member of the State Department, Max W. Bishop did obtain from the Peruvian minister to Japan, Dr... Literature on the Debacle,” Military Affairs 50, no. 1 (January 1986): 29. 181Wohlstetter, Pearl Harbor, 387; Toll, Pacific Crucible, 1941-1942, 118...2000. Coox, Alvin D. “Repulsing the Pearl Harbor Revisionists: The State of Present Literature on the Debacle,” Military Affairs 50, no. 1

  18. Sediment Budget on the Indiana Shore at Burns Harbor, Lake Michigan

    Science.gov (United States)

    2015-05-15

    1960s, and the USACE was well aware of potential littoral disruptions. Burns Waterway Harbor is located within a longshore littoral drift system with...formation of the Indiana Dunes 146 20/03/2015 16 pp 3 National Lakeshore (Engel 1983, Franklin and Schaeffer 1983, Higgs 1995). The Harbor is a...shores of Lake Michigan,” University of Illinois Press, Urbana, IL, 278 p. Higgs , S. (1995). “Eternal Vigilance: Nine Tales of Environmental

  19. Effects of sonic booms on breeding gray seals and harbor seals on Sable Island, Canada.

    Science.gov (United States)

    Perry, Elizabeth A; Boness, Daryl J; Insley, Stephen J

    2002-01-01

    The Concorde produces audible sonic booms as it passes 15 km north of Sable Island, Nova Scotia, where gray and harbor seals occur year round. The purpose of this research was to assess how sonic booms affect these seals. The intensity of the booms was measured and three types of data (beach counts, frequency of behavior, and heart rate) were collected before and after booms during the breeding seasons of the two species. In addition to the data taken during breeding, beach counts were made before and after booms during the gray seal moult. The greatest range in overpressure within a single boom was 2.70 psf during gray seal breeding and 2.07 psf during harbor seal breeding. No significant differences were found in the behavior or beach counts of gray seals following sonic booms, regardless of the season. Beach counts and most behaviors of harbor seals also did not differ significantly following booms, however, harbor seals became more vigilant. The heart rates of four gray seal mothers and three pups showed no clear change as a result of booms, but six male harbor seals showed a nonsignificant tendency toward elevated heart rates during the 15-s interval of the boom. These results suggest sonic booms produced by the Concorde, in level flight at altitude and producing on average a sonic boom of 0.9 psf, do not substantially affect the breeding behavior of gray or harbor seals.

  20. Harbor porpoise at-sea density off California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Marine Sanctuary Program (NMSP) updates and revises the management plans for each of its 13 sanctuaries. This process, which is open to the public,...

  1. Early human prostate adenocarcinomas harbor androgen-independent cancer cells.

    Directory of Open Access Journals (Sweden)

    Rita R Fiñones

    Full Text Available Although blockade of androgen receptor (AR signaling represents the main treatment for advanced prostate cancer (PrCa, many patients progress to a lethal phenotype of "Castration-Resistant" prostate cancer (CR-PrCa. With the hypothesis that early PrCa may harbor a population of androgen-unresponsive cancer cells as precursors to CR-recurrent disease, we undertook the propagation of androgen-independent cells from PrCa-prostatectomy samples of early, localized (Stage-I cases. A collection of 120 surgical specimens from prostatectomy cases was established, among which 54 were adenocarcinomas. Hormone-free cell culture conditions were developed allowing routine propagation of cells expressing prostate basal cell markers and stem/progenitor cell markers, and which proliferated as spheres/spheroids in suspension cultures. Colonies of androgen-independent epithelial cells grew out from 30/43 (70% of the adenocarcinoma cases studied in detail. Fluorescence microscopy and flow cytometry showed that CR-PrCa cells were positive for CD44, CD133, CK5/14, c-kit, integrin α2β1, SSEA4, E-Cadherin and Aldehyde Dehydrogenase (ALDH. All 30 CR-PrCa cell cultures were also TERT-positive, but negative for TMPRSS2-ERG. Additionally, a subset of 22 of these CR-PrCa cell cultures was examined by orthotopic xenografting in intact and castrated SCID mice, generating histologically typical locally-invasive human PrCa or undifferentiated cancers, respectively, in 6-8 weeks. Cultured PrCa cells and orthotopically-induced in vivo cancers lacked PSA expression. We report here the propagation of Cancer Initiating Cells (CIC directly from Stage I human PrCa tissue without selection or genetic manipulation. The propagation of stem/progenitor-like CR-PrCa cells derived from early human prostate carcinomas suggests the existence of a subpopulation of cells resistant to androgen-deprivation therapy and which may drive the subsequent emergence of disseminated CR-PrCa.

  2. Comparison of benthos and plankton for Waukegan Harbor Area of Concern, Illinois, and Burns Harbor-Port of Indiana non-Area of Concern, Indiana, in 2015

    Science.gov (United States)

    Eikenberry, Barbara C. Scudder; Olds, Hayley T.; Burns, Daniel J.; Dobrowolski, Edward G.; Schmude, Kurt L.

    2017-06-06

    During two seasonal sampling events in spring (June) and fall (August) of 2015, the U.S. Geological Survey collected benthos (benthic invertebrates) and plankton (zooplankton and phytoplankton) at three sites each in the Waukegan Harbor Area of Concern (AOC) in Illinois and in Burns Harbor-Port of Indiana, a non-AOC comparison site in Indiana. The study was done in cooperation with the U.S. Environmental Protection Agency and the Illinois Department of Natural Resources. Samples were collected concurrently for physical and chemical parameters (specific conductance, temperature, pH, dissolved oxygen, chlorophyll-a, total and volatile suspended solids in water samples; particle size and volatile-on-ignition solids of sediment in dredge samples). The purpose of the study was to assess whether or not aquatic communities at the AOC were degraded in comparison to communities at the non-AOC, which was presumed to be less impaired than the AOC. Benthos were collected by using Hester-Dendy artificial substrate samplers and a Ponar® dredge sampler to collect composited grabs of bottom sediment; zooplankton were collected by using tows from depth to the surface with a 63-micrometer mesh plankton net; phytoplankton were collected by using whole water samples composited from set depth intervals. Aquatic communities at the AOC and the non-AOC were compared by use of univariate statistical analyses with metrics such as taxa richness (number of unique taxa), diversity, and a multimetric Index of Biotic Integrity (IBI, for artificial-substrate samples only) as well as by use of multivariate statistical analyses of taxa relative abundances.Although benthos communities at Waukegan Harbor AOC were not rated as degraded in comparison to the non-AOC, metrics for zooplankton and phytoplankton communities did show some impairment for the 2015 sampling. Across seasons, benthos richness and diversity were significantly higher and rated as less degraded at the AOC compared to the non

  3. Toxic elements and organochlorines in harbor seals (Phoca vitulina richardsi), Kodiak, Alaska, USA

    Energy Technology Data Exchange (ETDEWEB)

    Miles, A.K. (Fish and Wildlife Service, Laurel, MD (United States)); Calkins, D.G. (Alaska Dept. of Fish and Game, Anchorage, AK (United States)); Coon, N.C. (Fish and Wildlife Service, Atlanta, GA (United States))

    1992-05-01

    Marine and estuarine habitats near urban or industrialized regions are vulnerable to contaminated runoff. Harbor seals (Phoca vitulina richardsi), which occur throughout much of the northern hemisphere, are useful mammalian biomonitors because they feed, reproduce, and rest near or on shore and are high-level trophic consumers. They have often been monitored for contaminants in Europe. To date, no studies have been reported on contaminants in harbor seals from industrialized areas of Alaska. In the vicinity of Anchorage, Alaska's largest urban and industrial city, harbor seals are sedentary and limited to coastal waters; some movements have been documents but there is no evidence of extensive migrations. Although some harbor seals in the Kodiak Archipelago move up to 100 km along the shore, strong fidelity to specific haulout sites is more common. These seals eat mainly non-migratory fishes and octopi. Harbor seal numbers have declined substantially from unknown causes in the southern part of the Kodiak Archipelago. The Alaska Department of Fish and Game (ADF G) suggested that the decline is a trend for the entire Kodiak region and other Alaskan waters. Contaminants have been suggested as a possible reason for the precipitous decline of Steller sea lions (Eumetopias jubatus) in the region, and were suspected in the decline of harbor seals. In this study, harbor seals were sampled from throughout the Kodiak Archipelago to determine concentrations of certain metals, metalloids, polychlorinated biphenyls (PCBs), and organochlorine pesticides, and to determine if these concentrations varied by sex or accumulated with age. All seals were collected within 75 km of Cook Inlet, an estuary next to Anchorage. The targeted elements or compounds were known to be toxic to a wide spectrum of organisms. 19 refs., 1 tab.

  4. Rethinking the Americans with Disabilities Act’s Insurance Safe Harbor

    Directory of Open Access Journals (Sweden)

    Valarie Blake

    2017-11-01

    Full Text Available Despite the importance of access to healthcare for the disabled, the Americans with Disabilities Act (ADA has made little inroads in reducing disability-based discrimination by health insurers in the United States. One reason is undoubtedly the ADA’s insurance safe harbor, which explicitly permits insurers to discriminate on the basis of disability in health insurance so long as the differential treatment is supported by actuarial data and is not just intended to disadvantage the disabled. While the safe harbor’s harms are somewhat limited by the advent of the Affordable Care Act (ACA, they are not entirely neutralized. This article argues that there are both practical and principled reasons for amending the ADA to remove the insurance safe harbor. Practically speaking, the ADA could prove a useful tool to challenge aspects of the ACA that place the disabled at a disadvantage, but the insurance safe harbor limits this reach in meaningful ways. From a more principled or philosophical lens, the insurance safe harbor is a law that perpetuates stigma against the disabled and that no longer reflects the views of American society. For these reasons, and many others, a rethinking of the ADA’s insurance safe harbor is necessary and timely.

  5. PCB and PAH speciation among particle types in contaminated harbor sediments and effects on PAH bioavailability

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, U.; Zimmerman, J.R.; Luthy, R.G. [Stanford University, Stanford, CA (USA). Dept. of Civil and Environmental Engineering

    2003-05-15

    This research provides particle-scale understanding of PCB and PAH distribution in sediments obtained from three urban locations in the United States: Hunters Point, CA; Milwaukee Harbor, WI; and Harbor Point, NY. The sediments comprised mineral grains and carbonaceous particles (primarily coal, coke, charcoal, pitch, cenospheres and wood). Carbonaceous particles contributed 5-7% of the total mass and 60-90% of the PCBs and PAHs. It appears that carbonaceous particles preferentially accumulate PCBs acting as sorbents in the aqueous environment if PCBs are released directly to the sediment or if deposited as airborne soot particles. Aerobic bioslurry treatment resulted in negligible PAH loss from the carbonaceous coal-derived material in Milwaukee Harbor sediment but resulted in 80% of the PAHs being removed from carbonaceous particles in Harbor Point sediment. PAHs in Harbor Point sediment were associated with coal tar pitch residue. PAHs present in semisolid coal tar pitch are more bioavailable than PAHs sorbed on carbonaceous particles such as coal, coke, charcoal and cenospheres. 24 refs., 10 figs.

  6. Reducing Vulnerability of Ports and Harbors to Earthquake and Tsunami Hazards

    Science.gov (United States)

    Wood, Nathan J.; Good, James W.; Goodwin, Robert F.

    2002-01-01

    Recent scientific research suggests the Pacific Northwest could experience catastrophic earthquakes in the near future, both from distant and local sources, posing a significant threat to coastal communities. Damage could result from numerous earthquake-related hazards, such as severe ground shaking, soil liquefaction, landslides, land subsidence/uplift, and tsunami inundation. Because of their geographic location, ports and harbors are especially vulnerable to these hazards. Ports and harbors, however, are important components of many coastal communities, supporting numerous activities critical to the local and regional economy and possibly serving as vital post-event, response-recovery transportation links. A collaborative, multi-year initiative is underway to increase the resiliency of Pacific Northwest ports and harbors to earthquake and tsunami hazards, involving Oregon Sea Grant (OSG), Washington Sea Grant (WSG), the National Oceanic and Atmospheric Administration Coastal Services Center (CSC), and the U.S. Geological Survey Center for Science Policy (CSP). Specific products of this research, planning, and outreach initiative include a regional stakeholder issues and needs assessment, a community-based mitigation planning process, a Geographic Information System (GIS) — based vulnerability assessment methodology, an educational web-site and a regional data archive. This paper summarizes these efforts, including results of two pilot port-harbor community projects, one in Yaquina Bay, Oregon and the other in Sinclair Inlet, Washington. Finally, plans are outlined for outreach to other port and harbor communities in the Pacific Northwest and beyond, using "getting started" workshops and a web-based tutorial.

  7. 77 FR 40628 - Draft Safe Harbor Agreement and Application for an Enhancement of Survival Permit for the Tres...

    Science.gov (United States)

    2012-07-10

    ... . SUPPLEMENTARY INFORMATION: Under a Safe Harbor Agreement, participating property owners voluntarily undertake...: June 4, 2012. Benjamin N. Tuggle, Regional Director, Southwest Region, Albuquerque, New Mexico. BILLING...

  8. Identifying best practices for "Safe Harbor" legislation to protect child sex trafficking victims: Decriminalization alone is not sufficient.

    Science.gov (United States)

    Barnert, Elizabeth S; Abrams, Susan; Azzi, Veronica F; Ryan, Gery; Brook, Robert; Chung, Paul J

    2016-01-01

    Several states have recently enacted "Safe Harbor" laws to redirect child victims of commercial sexual exploitation and child sex trafficking from the criminal justice system and into the child welfare system. No comprehensive studies of Safe Harbor law implementation exist. The nine state Safe Harbor laws enacted by 2012 were analyzed to guide state legislators, health professionals, law enforcement agents, child welfare providers, and other responders to the commercial sexual exploitation of children on the development and implementation of state Safe Harbor laws. The authors conducted 32 semi-structured interviews with Safe Harbor experts in these states. Participants conveyed that Safe Harbor legislation signified a critical paradigm shift, treating commercially sexually exploited youth not as criminals but as vulnerable children in need of services. However, Safe Harbor legislation varied widely and significant gaps in laws exist. Such laws alone were considered insufficient without adequate funding for necessary services. As a result, many well-meaning providers were going around the Safe Harbor laws by continuing to incarcerate commercially sexually exploited youth in the juvenile justice system regardless of Safe Harbor laws in place. This was done, to act, in their view, in what was the best interest of the victimized children. With imperfect laws and implementation, these findings suggest an important role for local and state responders to act together to protect victims from unnecessary criminalization and potential further traumatization. Published by Elsevier Ltd.

  9. Stable microbial communities in the sponge Crambe crambe from inside and outside a polluted Mediterranean harbor.

    Science.gov (United States)

    Gantt, Shelby E; López-Legentil, Susanna; Erwin, Patrick M

    2017-06-15

    Marine sponges have been shown to harbor diverse microbial symbiont communities that play key roles in host functioning, yet little is known about how anthropogenic disturbances impact sponge-microbe interactions. The Mediterranean sponge Crambe crambe is known to accumulate heavy metals in polluted harbors. In this study, we investigated whether the microbiome of C. crambe differed between sponges inhabiting a polluted harbor in Blanes (Spain) and a nearby (86% of all sequence reads. These results indicate that sponge microbiomes exhibit greater stability and pollution tolerance than their free-living microbial counterparts, potentially mitigating the effects of pollutants on coastal marine communities. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. A neurological comparative study of the harp seal (Pagophilus groenlandicus) and harbor porpoise (Phocoena phocoena) brain

    DEFF Research Database (Denmark)

    Walløe, Solveig; Eriksen, Nina; Dabelsteen, Torben

    2010-01-01

    The cetacean brain is well studied. However, few comparisons have been done with other marine mammals. In this study, we compared the harp seal (Pagophilus groenlandicus) and the harbor porpoise brain (Phocoena phocoena). Stereological methods were applied to compare three areas of interest...... cells, whereas the harp seal have 6.1 × 10(9) neocortical neurons and 17.5 × 10(9) neocortical glial cells. The harbor porpoise have significantly more neurons and glial cells in the auditory cortex than in the visual cortex, whereas the pattern was opposite for the harp seal. These results...... are the first to provide estimates of the number of neurons and glial cells in the neocortex of the harp seal and harbor porpoise brain and offer new data to the comparative field of mammalian brain evolution....

  11. Geoarchaeology and geomorphology of Phoenicus ancient harbor, NW coast of Egypt

    Science.gov (United States)

    Moustafa, Samah; Torab, Magdy

    2016-04-01

    Phoenicus Greek harbor located in SE coastline of Ras El Hekma area, west of Alexandria city for about 220 km. It is shaped as triangle with its headland extending into the Mediterranean Sea for about 15 km. It is occupied by sedimentary rocks belonging to the Tertiary and Quaternary Eras, the western coastline consists of Pleistocene, Separated polygons of limestone sheets and fossil lime stone, where there are coastal platforms, fluvial forms and solution holes. The location and description of Phoenicus ancient harbor were mentioned by some late writers (Fourtau,1893) & (Muller,1901), some geoarchaeological indicators were discovered by the authors such as fish tanks, well, remains of breakwater and wine press. The present work is mainly devoted to define the geomorphological and geoarchaelological indicators of Phoenicus Greek harbor site, based on detailed geomorphological and geoarchaelogical surveying, sampling, dating and mapping as well as satellite image interpretation and GIS techniques.

  12. The dynamics of fine-grain sediment dredged from Santa Cruz Harbor

    Science.gov (United States)

    Storlazzi, Curt D.; Conaway, Christopher H.; Presto, M. Katherine; Logan, Joshua B.; Cronin, Katherine; van Ormondt, Maarten; Lescinski, Jamie; Harden, E. Lynne; Lacy, Jessica R.; Tonnon, Pieter K.

    2011-01-01

    In the fall and early winter of 2009, a demonstration project was done at Santa Cruz Harbor, California, to determine if 450 m3/day of predominantly (71 percent) mud-sized sediment could be dredged from the inner portion of the harbor and discharged to the coastal ocean without significant impacts to the beach and inner shelf. During the project, more than 7600 m3 of sediment (~5400 m3 of fine-grain material) was dredged during 17 days and discharged approximately 60 m offshore of the harbor at a depth of 2 m on the inner shelf. The U.S. Geological Survey's Pacific Coastal and Marine Science Center was funded by the U.S. Army Corps of Engineers and the Santa Cruz Port District to do an integrated mapping and process study to investigate the fate of the mud-sized sediment dredged from the inner portion of Santa Cruz Harbor and to determine if any of the fine-grain material settled out on the shoreline and/or inner shelf during the fall and early winter of 2009. This was done by collecting highresolution oceanographic and sediment geochemical measurements along the shoreline and on the continental shelf of northern Monterey Bay to monitor the fine-grain sediment dredged from Santa Cruz Harbor and discharged onto the inner shelf. These in place measurements, in conjunction with beach, water column, and seabed surveys, were used as boundary and calibration information for a three-dimensional numerical circulation and sediment dynamics model to better understand the fate of the fine-grain sediment dredged from Santa Cruz Harbor and the potential consequences of disposing this type of material on the beach and on the northern Monterey Bay continental shelf.

  13. Phaeobacter inhibens from the Roseobacter clade has an environmental niche as a surface colonizer in harbors

    DEFF Research Database (Denmark)

    Gram, Lone; Rasmussen, Bastian Barker; Wemheuer, Bernd

    2015-01-01

    Phaeobacter inhibens belongs to the marine Roseobacter clade and is important as a carbon and sulfur metabolizer, a biofilm former and producer of the antibiotic tropodithietic acid (TDA). The majority of cultured strains have been isolated from marine aquaculture sites, however, their niche...... organisms or biofilms on inert surfaces) in Jyllinge Harbor during late summer and autumn, but not during winter and spring in 2009, 2011, and 2012. P. inhibens strains were also isolated from biofilms at three other Danish harbors (in 2012), but not from the surrounding seawater. Ten of the 14 samples from...

  14. An Evaluation of the Harbors of Iwakuni and Kure, Japan as Typhoon Havens

    Science.gov (United States)

    1975-12-01

    Harima Heavy Industries , LTD (IHI). IHI has the capacity to handle and repair ships over 100,000 tons. The excellent anchorages, docks and repair...Hiroshima Bay (Iwakuni) .45 5.1.4 Kure 46 5.1.5 Wave Action In Kure Harbor 49 5.1.6 Storm Surge In Kure Harbor 49 6. PREPARATION FOR HEAVY WEATHER IN THE...docks and repair facilities are available at Kure with a large part of the waterfront area being occupied by the docks and buildings of Ishikawajima

  15. Safe Harbor Legislation for Juvenile Victims of Sex Trafficking: A Myopic View of Improvements in Practice

    Directory of Open Access Journals (Sweden)

    Kimberly Mehlman-Orozco

    2015-02-01

    Full Text Available Current social and political realties have focused attention on human trafficking in the United States. Although new mechanisms for criminalizing offenders and protecting victims are increasingly funded and implemented across the country, empirical exploration into the efficacy of these interventions is lacking. This article uses yearly count data on juvenile prostitution arrests aggregated at the state level to explore the criminalization of commercial sexually exploited children post safe harbor policy implementation. Preliminary data from four states suggests that the passage of safe harbor laws may not reduce the number of juveniles arrested for prostitution crimes. Implications for future research are discussed.

  16. Harbor Seal (Phoca vitulina) Reproductive Advertisement Behavior and the Effects of Vessel Noise

    Science.gov (United States)

    Matthews, Leanna P.

    Harbor seals (Phoca vitulina) are a widely distributed pinniped species that mate underwater. Similar to other aquatically mating pinnipeds, male harbor seals produce vocalizations during the breeding season that function in male-male interactions and possibly as an attractant for females. I investigated multiple aspects of these reproductive advertisement displays in a population of harbor seals in Glacier Bay National Park and Preserve, Alaska. First, I looked at vocal production as a function of environmental variables, including season, daylight, and tidal state. Vocalizations were highly seasonal and detection of these vocalizations peaked in June and July, which correspond with the estimated time of breeding. Vocalizations also varied with light, with the lowest probability of detection during the day and the highest probability of detection at night. The high probability of detection corresponded to when females are known to forage. These results are similar to the vocal behavior of previously studied populations. However, unlike previously studied populations, the detection of harbor seal breeding vocalizations did not vary with tidal state. This is likely due to the location of the hydrophone, as it was not near the haul out and depth was therefore not significantly influenced by changes in tidal height. I also investigated the source levels and call parameters of vocalizations, as well as call rate and territoriality. The average source level of harbor seal breeding vocalizations was 144 dB re 1 ?Pa at 1 m and measurements ranged from 129 to 149 dB re 1 ?Pa. Analysis of call parameters indicated that vocalizations of harbor seals in Glacier Bay were similar in duration to other populations, but were much lower in frequency. During the breeding season, there were two discrete calling areas that likely represent two individual males; the average call rate in these display areas was approximately 1 call per minute. The harbor seal breeding season also

  17. Tohoku's earthquake of Friday March 11, 2011 (5:46 UT), magnitude 9.0, off Honshu island (Japan); Seisme de Tohoku au large de l'Ile d'Honshu (Japon) du vendredi 11 mars 2011 (5h46 TU) Magnitude = 9,0

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    On Friday March 11, 2011, at 5:46 UT (2:46 PM local time), a magnitude 9.0 earthquake took place at 80 km east of Honshu island (Japan). The earthquake generated a tsunami which led to the loss of the cooling systems of the Fukushima Dai-ichi and Fukushima Daini power plants. This paper describes the seismo-tectonic and historical seismic context of the Japan archipelago and the first analyses of the Tohoku earthquake impact: magnitudes of first shock and of aftershocks, impact on nuclear facilities (maximum acceleration values detected with respect to design basis values, subsidence of coastal areas and submersion of power plant platforms). (J.S.)

  18. Major earthquake of Friday March 11, 2011, magnitude 8.9 at 5:46 UT, off Honshu island (Japan); Seisme majeur au large de l'Ile d'Honshu (Japon) du vendredi 11 mars 2011 Magnitude = 8,9 a 5h46 (TU)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    On Friday March 11, 2011, at 5:46 UT (2:46 PM local time), a magnitude 8.9 earthquake took place at 80 km east of Honshu island (Japan). The earthquake affected a large part of the Honshu territory and led to the automatic emergency shutdown of all nuclear power plants of the east coast. This paper recalls first the seismo-tectonic and historical seismic context of the Japan archipelago and the first analyses of the Tohoku earthquake impact on nuclear facilities. At the time of publication of this information report, no radioactive release in the environment and no anomaly at the Tokai-Mura and Rokkasho-Mura sites were mentioned. However, the evacuation of populations in a 3 to 10 km area around the Fukushima-Dai-ichi power plant had been ordered by the Governor as preventive measure, which made one think that the situation at this specific site was particularly worrying. (J.S.)

  19. 76 FR 20287 - Superfund Site, New Bedford Harbor, New Bedford, MA: Anchorage Ground and Regulated Navigation Area

    Science.gov (United States)

    2011-04-12

    ... New Bedford Harbor hurricane barrier in the outer harbor. The pilot cap consists of sand and gravel... will still be available for use; the number of vessels using the anchorage is limited due to depth...'' N, 070 54'26.9'' W; thence along the shoreline and south side of the hurricane barrier to the...

  20. 75 FR 33999 - Safety Zone; Fourth of July Fireworks Event, Cape Charles City Harbor, Cape Charles, VA

    Science.gov (United States)

    2010-06-16

    ... of Cape Charles City Harbor centered on position 37 15'59'' N/ 076 01'12'' W (NAD 1983). Due to the... Harbor within the area bounded by a 420-foot radius circle centered on position 37 15'59'' N/ 076 01'12... rulemaking process. Small businesses may send comments on the actions of Federal employees who enforce, or...

  1. 33 CFR 165.776 - Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico 165.776 Section 165.776 Navigation and Navigable Waters COAST... Guard District § 165.776 Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico (a...

  2. The effects of acoustic alarms on the behavior of harbor porpoises (Phocoena phocoena) in a floating pen

    NARCIS (Netherlands)

    Kastelein, R.A.; Rippe, H.T.; Vaughan, N.; Schooneman, N.M.; Verboom, W.C.; Haan, D.de

    2000-01-01

    In an attempt to test the effectiveness of sounds in deterring harbor porpoises from nets and reducing porpoise bycatch in gill net fisheries, two harbor porpoises, kept in a large floating pen at Neeltje Jans, The Netherlands, were subjected to 3 different underwater sounds. The effect of each

  3. 26 CFR 1.414(r)-5 - Qualified separate line of business-administrative scrutiny requirement-safe harbors.

    Science.gov (United States)

    2010-04-01

    ...-administrative scrutiny requirement-safe harbors. 1.414(r)-5 Section 1.414(r)-5 Internal Revenue INTERNAL REVENUE...-Sharing, Stock Bonus Plans, Etc. § 1.414(r)-5 Qualified separate line of business—administrative scrutiny requirement—safe harbors. (a) In general. A separate line of business (as determined under § 1.414(r)-3...

  4. 75 FR 55975 - Safety Zone; San Diego Harbor Shark Fest Swim; San Diego Bay, San Diego, CA

    Science.gov (United States)

    2010-09-15

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; San Diego Harbor Shark Fest Swim; San Diego... Shark Fest Swim, consisting of 600 swimmers swimming a predetermined course. The sponsor will provide 26...; San Diego Harbor Shark Fest Swim; San Diego Bay, San Diego, CA. (a) Location. The following area is a...

  5. 78 FR 11116 - Safety Zone; Mamaroneck Beach and Yacht Club Fireworks, Mamaroneck Harbor, Long Island Sound, NY

    Science.gov (United States)

    2013-02-15

    ..., Mamaroneck Harbor, Long Island Sound, NY AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking... Island Sound in the vicinity of Mamaroneck Harbor for a fireworks display. This temporary safety zone is... is intended to restrict all vessels from a portion of Long Island Sound before, during, and...

  6. Developement of watershed and reference loads for a TMDL in Charleston Harbor System, SC.

    Science.gov (United States)

    Silong Lu; Devenra Amatya; Jamie Miller

    2005-01-01

    It is essential to determine point and non-point source loads and their distribution for development of a dissolved oxygen (DO) Total Maximum Daily Load (TMDL). A series of models were developed to assess sources of oxygen-demand loadings in Charleston Harbor, South Carolina. These oxygen-demand loadings included nutrients and BOD. Stream flow and nutrient...

  7. 75 FR 53574 - Safety Zone; Fireworks Displays, Potomac River, National Harbor, MD

    Science.gov (United States)

    2010-09-01

    ... [Docket No. USCG-2010-0776] RIN 1625-AA00 Safety Zone; Fireworks Displays, Potomac River, National Harbor... necessary to provide for the safety of life on navigable waters during five fireworks displays launched from... necessary to protect persons and vessels against the hazards associated with a fireworks display on...

  8. 78 FR 41898 - Safety Zone; Fireworks Display, Baltimore Harbor; Baltimore, MD

    Science.gov (United States)

    2013-07-12

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Fireworks Display, Baltimore Harbor... is necessary to provide for the safety of life on navigable waters during a fireworks display... Football League, of New York, NY, will sponsor a fireworks display launched from barges located in...

  9. 76 FR 57087 - Stone Harbor Investment Partners LP, et al.; Notice of Application

    Science.gov (United States)

    2011-09-15

    ..., or cause more than 10% of the acquired company's voting stock to be owned by investment companies and... COMMISSION Stone Harbor Investment Partners LP, et al.; Notice of Application September 7, 2011. AGENCY... the Investment Company Act of 1940 (``Act'') for an exemption from rule 12d1-2(a) under the Act...

  10. 78 FR 56681 - Intent To Prepare a Supplemental Environmental Impact Statement for the Grays Harbor Navigation...

    Science.gov (United States)

    2013-09-13

    ... INFORMATION CONTACT: Mr. Kevin McKeag, Environmental and Cultural Resources Branch, U.S. Army Corps of... Rivers and Harbors Appropriations Act of 1899. Dredging of the navigation channel to a depth of minus 38... treaty rights; wetland and riparian habitat; wildlife; vehicle traffic; cultural, historic, and...

  11. 77 FR 19573 - Safety Zone; Wedding Fireworks Display, Boston Inner Harbor, Boston, MA

    Science.gov (United States)

    2012-04-02

    ... in the vicinity of Anthony's Pier 4, Boston, MA for a wedding fireworks display. This temporary... ``Document Type'' drop down menu select ``Proposed Rule'' and insert ``USCG-2012-0130'' in the ``Keyword... Boston Inner Harbor in the vicinity of Anthony's Pier 4, Boston, MA. The Captain of the Port (COTP...

  12. Seroprevalence of Brucella antibodies in harbor seals in Alaska, USA, with age, regional, and reproductive comparisons.

    Science.gov (United States)

    Hoover-Miller, A; Dunn, J L; Field, C L; Blundell, G; Atkinson, S

    2017-09-20

    Populations of harbor seal Phoca vitulina in the Gulf of Alaska have dramatically declined during the past 4 decades. Numbers of seals in Glacier Bay, in southeast Alaska, USA, have also declined despite extensive protection. Causes of the declines and slow recovery are poorly understood. Brucellosis is a zoonotic disease that adversely affects reproduction in many domestic species. We measured the seroprevalence of Brucella antibodies in 554 harbor seals in 3 Alaska locations: Prince William Sound (PWS), Glacier Bay (GB), and Tracy Arm Fords Terror (TAFT) Wilderness Area. Objectives included testing for regional, sex, age, and female reproductive state differences in Brucella antibody seroprevalence, persistence in titers in recaptured seals, and differences in titers between mother seals and their pups. Overall, 52% of adults (AD), 53% of subadults (SA), 77% of yearlings (YRL), and 26% of Brucella. Results show higher seroprevalence (64%) for AD and SA seals in the depressed and declining populations in PWS and GB than in TAFT (29%). Lactating females were less likely to be seropositive than other AD females, including pregnant females. Further research is needed to seek evidence of Brucella infection in Alaskan harbor seals, identify effects on neonatal viability, and assess zoonotic implications for Alaska Natives who rely on harbor seals for food.

  13. Hamiltonian Boussinesq simulations for waves entering a harbor with access channel

    NARCIS (Netherlands)

    Kurnia, R.; Badriana, M. R.; van Groesen, E.

    2018-01-01

    Numerical simulations are often used to predict the deformation of waves and their impact on structures in harbors and access channels. An underprediction of these waves could lead to structural failure or ship accidents, so accurate numerical models should be capable of capturing the complex

  14. 78 FR 31415 - Safety Zone; USA Triathlon; Milwaukee Harbor, Milwaukee, WI

    Science.gov (United States)

    2013-05-24

    ... No. USCG-2013-0140] RIN 1625-AA00 Safety Zone; USA Triathlon; Milwaukee Harbor, Milwaukee, WI AGENCY... (adjusted for inflation) or more in any one year. Though this rule would not result in such an expenditure.... Add Sec. 165.T09-0140 to read as follows: Sec. 165.T09-0140 Safety Zone; USA Triathlon, Milwaukee...

  15. 78 FR 19158 - Safety Zone; USA Triathlon, Milwaukee Harbor, Milwaukee, WI

    Science.gov (United States)

    2013-03-29

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; USA Triathlon, Milwaukee Harbor, Milwaukee... sector of $100,000,000 (adjusted for inflation) or more in any one year. Though this proposed rule would... Delegation No. 0170.1. 2. Add Sec. 165.T09-0140 to read as follows: Sec. 165.T09-0140 Safety Zone; USA...

  16. Evaluation of Resuspension from Propeller Wash in Pearl Harbor and San Diego Bay

    Science.gov (United States)

    2014-07-01

    Wang et al., 2000; 2004), sediment transport for Pearl Harbor, HI (Wang et al., 2009a; 2009b) and TMDL for fecal coliform and Combined Sewage...Sewer Overflows in the Port Washington Narrows and Fecal Coliform Transport in Sinclair and Dyes Inlets, Washington. Prepared by Space and Naval

  17. 76 FR 9273 - Special Local Regulations for Marine Events; Severn River, Spa Creek and Annapolis Harbor...

    Science.gov (United States)

    2011-02-17

    ... River, Spa Creek and Annapolis Harbor, Annapolis, MD AGENCY: Coast Guard, DHS. ACTION: Notice of... swim segment of the ``TriRock Annapolis'' triathlon, a marine event to be held on the waters of Spa... segment of the event will occur from 7 a.m. to 8:30 a.m. and will be located in Spa Creek and Annapolis...

  18. 33 CFR 80.1490 - Apra Harbor, U.S. Territory of Guam.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, U.S. Territory of Guam. 80.1490 Section 80.1490 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND....S. Territory of Guam. A line drawn from the westernmost extremity of Orote Island to the westernmost...

  19. Application of Sister Chromatid Exchange in Marine Polychaetes to Black Rock Harbor Sediment. Laboratory Documentation Phase.

    Science.gov (United States)

    1985-01-01

    Gentile; Technical Coordinator was Mr. Walter Galloway; and Project Manager was Mr. Allan Beck. -~ Special thanks are due to Capt. Robert Alix and Dr...Research Board of Canada, Vol 34, pp 266-269. Lake, J., Hoffman, G., and Schimmel, S. 1984. "The Bioaccumulation of Contaminants /From Black Rock Harbor

  20. Synergistic growth inhibition of cancer cells harboring the RET/PTC1 ...

    Indian Academy of Sciences (India)

    Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death. ANTÓNIO PEDRO GONÇALVES, ARNALDO VIDEIRA, VALDEMAR MÁXIMO and PAULA SOARES. J. Biosci. 36(4), September 2011, 639-648, © Indian Academy of Sciences.

  1. Synergistic growth inhibition of cancer cells harboring the RET/PTC1 ...

    Indian Academy of Sciences (India)

    Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death. ANTÓNIO PEDRO GONÇALVES. 1,2,*, ARNALDO VIDEIRA. 1,2. , VALDEMAR MÁXIMO. 3,4 and PAULA SOARES. 3,4. 1Instituto de Biologia Molecular e Celular, Universidade do ...

  2. 75 FR 42069 - Expansion of Foreign-Trade Zone 152, Burns Harbor, Indiana

    Science.gov (United States)

    2010-07-20

    ... Foreign-Trade Zones Board Expansion of Foreign-Trade Zone 152, Burns Harbor, Indiana Pursuant to its authority under the Foreign-Trade Zones (FTZ) Act of June 18, 1934, as amended (19 U.S.C. 81a-81u), the Foreign- Trade Zones Board (the Board) adopts the following Order: Whereas, the Ports of Indiana, grantee...

  3. 76 FR 38302 - Safety Zone; Cape Charles Fireworks, Cape Charles Harbor, Cape Charles, VA

    Science.gov (United States)

    2011-06-30

    ... navigable waters of Cape Charles City Harbor centered on position 37 15'46.5'' N/076 01'30'' W (NAD 1983... of materials, performance, design, or operation; test methods; sampling procedures; and related... the human environment. This rule is categorically excluded, under figure 2-1, paragraph (34)(g), of...

  4. Oral Language Development in a Child with Floating-Harbor Syndrome.

    Science.gov (United States)

    Muir, Nicole Y.; Allard, Glenn B.; Greenberg, Cheryl

    1999-01-01

    This report presents a three-year case study of oral-language skill development in a child with Floating-Harbor syndrome, a rare condition characterized by short stature, expressive language delay, and triangular facies. It discusses initial presenting speech and language characteristics, the naturalistic language intervention used, and long-term…

  5. The Floating-Harbor syndrome: two affected siblings in a family.

    Science.gov (United States)

    Fryns, J P; Kleczkowska, A; Timmermans, J; van den Berghe, H

    1996-10-01

    In this report we describe two siblings with pre- and postnatal growth retardation and clinical signs and symptoms most compatible with the diagnosis of Floating-Harbor syndrome. The oldest sibling, a girl, died in the first year of life from recurrent infections. The younger sibling, a male, is now 16.5 years old and mildly mentally retarded.

  6. Speech-Language Evaluation and Rehabilitation Treatment in Floating-Harbor Syndrome: A Case Study

    Science.gov (United States)

    Angelillo, Nicola; Di Costanzo, Brigida; Barillari, Umberto

    2010-01-01

    Floating-Harbor syndrome is a rare congenital disorder characterized by specific facial features, short stature associated with significantly delayed bone age and language impairment. Although language delay is a cardinal manifestation of this syndrome, few reports describe the specific language difficulties of these patients, particularly the…

  7. 33 CFR 110.214 - Los Angeles and Long Beach harbors, California.

    Science.gov (United States)

    2010-07-01

    ... Small Craft Note e. P Long Beach Harbor ......do Note f. Q ......do ......do Notes c, g. Notes: a.... (ii) No vessel while carrying, loading, or unloading division 1.1 or 1.2 materials as defined in 49... (explosive) materials as defined in 49 CFR 173.50, or Cargoes of Particular Hazard (COPH) as defined in 33...

  8. Respiratory properties of blood in the harbor porpoise, Phocoena phocoena

    DEFF Research Database (Denmark)

    Soegaard, Lisette B.; Hansen, Marie Niemann; van Elk, Cornelis

    2012-01-01

    -bicarbonate buffer value was moderately higher than in terrestrial mammals and increased upon deoxygenation. Plasma bicarbonate was also relatively high, contributing to increase the overall buffer capacity. The apparent Cl– permeability of harbor porpoise erythrocytes was similar to the human value at 37°C, showing...

  9. Effects of harbor activities on sediment quality in a semi-arid region in Brazil.

    Science.gov (United States)

    Moreira, Lucas B; Castro, Ítalo B; Hortellani, Marcos A; Sasaki, Silvio T; Taniguchi, Satie; Petti, Mônica A V; Fillmann, Gilberto; Sarkis, Jorge E S; Bícego, Márcia C; Costa-Lotufo, Leticia V; Abessa, Denis M S

    2017-01-01

    Tropical marine environments are rich in biodiversity and the presence of harbor activities in these areas can harm the coastal ecosystems. In this study, we assessed sediment quality of two harbors from a tropical region in Brazil by applying multiple lines-of-evidence approach. This approach included the integration of results on: (1) grain size, organic matter, organic carbon, nitrogen, phosphorus, trace metals, polycyclic aromatic hydrocarbons, linear alkylbenzenes, and tributyltin; (2) acute toxicity of whole sediments and chronic toxicity of liquid phases; and (3) benthic community descriptors. Our results revealed that the main contaminants detected in sediments from Mucuripe and Pecém Harbors were chromium, copper, nitrogen, zinc, and tributyltin. These toxicants arise from typical harbor activities. However, the changes in benthic composition and structure appear to depend on a combination of physical impacts, such as the deposition of fine sediments and the toxic potential of contaminants, especially in Mucuripe. Thus, apart from toxicants physical processes are important in describing risks. This information may assist in management and conservation of marine coastal areas. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Side-scan imagery of Apra Harbor, Guam U.S. Territory

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gridded side-scan imagery collected in Apra Harbor, Guam U.S. Territory, USA. The GeoTIFF and Arc ASCII file includes data that were collected using a Klein 3000...

  11. 78 FR 28492 - Special Local Regulation; Low Country Splash, Wando River, Cooper River, and Charleston Harbor...

    Science.gov (United States)

    2013-05-15

    ... of Proposed Rulemaking A. Regulatory History and Information On March 26, 2013, we published a notice... River, Cooper River, and Charleston Harbor in Charleston, SC. The race will consist of approximately 500 swimmers. The race will commence at Daniel Island Pier, transit south in the Wando River, crossing the...

  12. 78 FR 61821 - Taking of Marine Mammals Incidental to Commercial Fishing Operations; Harbor Porpoise Take...

    Science.gov (United States)

    2013-10-04

    .... 2012. \\2\\ Waring et al. 2013. \\3\\ C.D. Orphanides, personal communication, September 16, 2013. [[Page... further mortality declines towards ZMRG. Response: NMFS acknowledges that the Plan has not reached ZMRG. However, harbor porpoise bycatch in U.S. gillnet fisheries is declining significantly below the PBR level...

  13. 33 CFR 110.189a - Key West Harbor, Key West, Fla., naval explosives anchorage area.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Key West Harbor, Key West, Fla..., Key West, Fla., naval explosives anchorage area. (a) The anchorage ground. A circular area with its... this section shall be enforced by the Commander, U.S. Naval Base, Key West, Fla., and any other...

  14. 77 FR 60109 - Takes of Marine Mammals Incidental to Specified Activities; Harbor Activities Related to the...

    Science.gov (United States)

    2012-10-02

    ... on June 5, 2012. ] These activities (i.e., transport vessel operations, cargo movement activities...-loading operations and the cargo movement activities, the increased presence of personnel, and harbor... description of the animal(s) involved; Fate of the animal(s); and Photographs or video footage of the animal(s...

  15. 76 FR 38153 - California State Nonroad Engine Pollution Control Standards; Commercial Harbor Craft Regulations...

    Science.gov (United States)

    2011-06-29

    ... nitrogen from new and in-use diesel- fueled engines on commercial harbor craft. CARB has requested that EPA... . Fax: (202) 566-1741. Mail: Air and Radiation Docket, Docket ID No. EPA-HQ-OAR- 2011-0549, U.S... proceeding are contained in the Air and Radiation Docket and Information Center, maintained in Docket ID No...

  16. 75 FR 32275 - Regulated Navigation Area; Gulf Intracoastal Waterway, Inner Harbor Navigation Canal, Harvey...

    Science.gov (United States)

    2010-06-08

    ..., Inner Harbor Navigation Canal, Harvey Canal, Algiers Canal, New Orleans, LA AGENCY: Coast Guard, DHS...), Harvey Canal, and Algiers Canal during severe hurricane conditions. Vessels will not be permitted to stay... communities within the IHNC, Harvey, and Algiers Canals from potential hazards associated with vessels being...

  17. Novel B19-like parvovirus in the brain of a harbor seal

    NARCIS (Netherlands)

    R. Bodewes (Rogier); A.R. García (Ana Rubio); L.C.M. Wiersma (Lidewij); S. Getu (Sarah); M. Beukers (Martijn); C.M.E. Schapendonk (Claudia); P.R.W.A. van Run (Peter); M.W.G. van de Bildt (Marco); M.J. Poen (Marjolein); N. Osinga (Nynke); G.J. Sánchez Contreras (Guillermo); T. Kuiken (Thijs); S.L. Smits (Saskia); A.D.M.E. Osterhaus (Albert)

    2013-01-01

    textabstractUsing random PCR in combination with next-generation sequencing, a novel parvovirus was detected in the brain of a young harbor seal (Phoca vitulina) with chronic non-suppurative meningo-encephalitis that was rehabilitated at the Seal Rehabilitation and Research Centre (SRRC) in the

  18. The isolation and partial characterization of a highly pathogenic herpesvirus from the harbor seal (Phoca vitulina).

    NARCIS (Netherlands)

    A.D.M.E. Osterhaus (Albert); H. Yang (Hong); H.E.M. Spijkers (Ine); J. Groen (Jan); J.S. Teppema; G. van Steenis (Bert)

    1985-01-01

    textabstractThis report describes the first isolation and partial characterization of a herpesvirus from the harbor seal (Phoca vitulina). The virus was isolated during a disease outbreak in a group of young seals nursed in a seal orphanage in The Netherlands. Almost half of the seals died with

  19. 33 CFR 165.120 - Safety Zone: Chelsea River, Boston Inner Harbor, Boston, MA.

    Science.gov (United States)

    2010-07-01

    ... is a safety zone: The waters of the Chelsea River, Boston Inner Harbor, for 100 yards upstream and... the Jenny Dock (approximate position latitude 42°23′05.2″ N., longitude 71°01′35.8″ W.)—or the Mobile...

  20. Revisiting "Pearl Harbor": Resistance to Reel and Real Events in an English Language Classroom

    Science.gov (United States)

    Mackie, Ardiss; Norton, Bonny

    2006-01-01

    In this article, we draw on disruptive scenes in a postsecondary classroom to examine a critical incident concerning conflicting readings of the film "Pearl Harbor" (2001). We raise crucial questions for pedagogical work with popular film: Who speaks for whom about the meaning of a given film? Under what conditions do students resist…

  1. 77 FR 2019 - Security Zone; Passenger Vessel SAFARI EXPLORER Arrival/Departure, Kaunakakai Harbor, Molokai, HI

    Science.gov (United States)

    2012-01-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zone; Passenger Vessel SAFARI EXPLORER Arrival/ Departure, Kaunakakai Harbor, Molokai, HI AGENCY: Coast Guard, DHS. ACTION: Temporary interim rule with...

  2. 77 FR 24381 - Security Zone; Passenger Vessel SAFARI EXPLORER Arrival/Departure, Kaunakakai Harbor, Molokai, HI

    Science.gov (United States)

    2012-04-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zone; Passenger Vessel SAFARI EXPLORER Arrival/ Departure, Kaunakakai Harbor, Molokai, HI AGENCY: Coast Guard, DHS. ACTION: Temporary interim rule...

  3. Hearing thresholds of a harbor porpoise (Phocoena phocoena) for playbacks of multiple pile driving strike sounds

    NARCIS (Netherlands)

    Kastelein, R.A.; Hoek, L.; Gransier, R.; Jong, C.A.F. de

    2013-01-01

    Pile driving is presently the most common method used to attach wind turbines to the sea bed. To assess the impact of pile driving sounds on harbor porpoises, it is important to know at what distance these sounds can be detected. Using a psychophysical technique, a male porpoise’s hearing thresholds

  4. PROPERTIES OF NEW YORK/NEW JERSEY HARBOR SEDIMENTS.

    Energy Technology Data Exchange (ETDEWEB)

    JONES, K.W.; FENG, H.; STERN, E.A.; NEUHAEUSLER, U.; OSAN, J.; MARINKOVIC, N.; SONG, Z.

    2005-05-20

    Sediments found in waterways around the world may contain toxic compounds of anthropogeilic origin that can harm the environment and human health. As a result, it is often necessary to remove them and find disposal methods that are environmentally and economically acceptable. Here, we report on results obtained in an experimental program to characterize the nature of the sediment contamination. The objective was to gain a better understanding of the properties of the sediments to develop better methods for understanding the fate and transport of the contaminants and for improving methods for their removal from the sediments. Our investigations made use of x-ray facilities at the Brookhaven National Synchrotron Light Source (NSLS) and the European Synchrotron Radiation Facility (ESRF) at Grenoble, France. The experiments included: measurements of the microstructure of the sediments using computed microtomography, x-ray absorption, and fluorescence microscopy with resolutions as low as 0.2 micrometers to obtain information on the relationships of organic and mineral components of the sediments and on the distribution of contaminants on the surfaces of the sediment grains, investigation of functional groups of chemical compounds using x-ray absorption near-edge spectroscopy (XANES) and Fourier Transform Infrared Spectroscopy (FTIR). Scanning electron microscopy (SEM) and electron probe measurements were made to ascertain the morphology of the sediment surfaces and the distribution of metals on individual sediment grains.

  5. Diving Related Changes in the Blood Oxygen Stores of Rehabilitating Harbor Seal Pups (Phoca vitulina).

    Science.gov (United States)

    Thomas, Amber; Ono, Kathryn

    2015-01-01

    Harbor seal (Phoca vitulina) pups begin diving within hours of birth, stimulating the development of the blood oxygen (O2) stores necessary to sustain underwater aerobic metabolism. Since harbor seals experience a brief nursing period, the early-life development of these blood O2 stores is necessary for successful post-weaning foraging. If mothers and pups become prematurely separated, the pup may be transported to a wildlife rehabilitation center for care. Previous studies suggest that the shallow pools and lack of diving in rehabilitation facilities may lead to under-developed blood O2 stores, but diving behavior during rehabilitation has not been investigated. This study aimed to simultaneously study the diving behaviors and blood O2 store development of rehabilitating harbor seal pups. Standard hematology measurements (Hct, Hb, RBC, MCV, MCH, MCHC) were taken to investigate O2 storage capacity and pups were equipped with time-depth recorders to investigate natural diving behavior while in rehabilitation. Linear mixed models of the data indicate that all measured blood parameters changed with age; however, when compared to literature values for wild harbor seal pups, rehabilitating pups have smaller red blood cells (RBCs) that can store less hemoglobin (Hb) and subsequently, less O2, potentially limiting their diving capabilities. Wild pups completed longer dives at younger ages (maximum reported dives were observed (maximum during rehabilitation: 13.6 min at 89 days of age). Further, this study suggests that there may be a positive relationship between RBC size and the frequency of long duration dives. Thus, rehabilitating harbor seal pups should be encouraged to make frequent, long duration dives to prepare themselves for post-release foraging.

  6. PCB and PAH speciation among particle types in contaminated harbor sediments and effects on PAH bioavailability.

    Science.gov (United States)

    Ghosh, Upal; Zimmerman, John R; Luthy, Richard G

    2003-05-15

    This research provides particle-scale understanding of PCB and PAH distribution in sediments obtained from three urban locations in the United States: Hunters Point, CA; Milwaukee Harbor, WI; and Harbor Point, NY. The sediments comprised mineral grains (primarily sand, silt, and clays) and carbonaceous particles (primarily coal, coke, charcoal, pitch, cenospheres, and wood). The carbonaceous sediment fractions were separated from the mineral fractions based on their lower density and were identified by petrographic analysis. In all three sediments, carbonaceous particles contributed 5-7% of the total mass and 60-90% of the PCBs and PAHs. The production of carbonaceous particles is not known to be associated with PCB contamination, and it is very unlikely that these particles can be the source of PCBs in the environment Thus, it appears that carbonaceous particles preferentially accumulate PCBs acting as sorbents in the aqueous environment if PCBs are released directly to the sediment or if deposited as airborne soot particles. Aerobic bioslurry treatment resulted in negligible PAH loss from the carbonaceous coal-derived material in Milwaukee Harbor sediment but resulted in 80% of the PAHs being removed from carbonaceous particles in Harbor Point sediment. Microscale PAH extraction and analysis revealed that PAHs in Harbor Point sediment were associated mainly with coal tar pitch residue. PAHs present in semisolid coal tar pitch are more bioavailable than PAHs sorbed on carbonaceous particles such as coal, coke, charcoal, and cenosphere. Results of this study illustrate the importance of understanding particle-scale association of hydrophobic organic contaminants for explaining bioavailability differences among sediments.

  7. An evaluation of the toxicity of contaminated sediments from Waukegan Harbor, Illinois, following remediation

    Science.gov (United States)

    Kemble, N.E.; Hardesty, D.G.; Ingersoll, C.G.; Johnson, B. Thomas; Dwyer, F.J.; MacDonald, D.D.

    2000-01-01

    Waukegan Harbor in Illinois was designated as a Great Lakes Area of Concern due to high concentrations of sediment-associated polychlorinated biphenyls (PCBs). The objective of this study was to evaluate the toxicity of 20 sediment samples collected after remediation (primarily dredging) of Waukegan Harbor for PCBs. A 42-day whole sediment toxicity test with the amphipod Hyalella azteca (28-day sediment exposure followed by a 14-day reproductive phase) and sediment toxicity tests with Microtox® were conducted to evaluate sediments from Waukegan Harbor. Endpoints measured were survival, growth, and reproduction (amphipods) and luminescent light emission (bacteria). Survival of amphipods was significantly reduced in 6 of the 20 sediment samples relative to the control. Growth of amphipods (either length or weight) was significantly reduced relative to the control in all samples. However, reproduction of amphipods identified only two samples as toxic relative to the control. The Microtox basic test, conducted with organic extracts of sediments identified only one site as toxic. In contrast, the Microtox solid-phase test identified about 50% of the samples as toxic. A significant negative correlation was observed between reproduction and the concentration of three polynuclear aromatic hydrocarbons (PAHs) normalized to total organic carbon. Sediment chemistry and toxicity data were evaluated using sediment quality guidelines (consensus-based probable effect concentrations, PECs). Results of these analyses indicate that sediment samples from Waukegan Harbor were toxic to H. azteca contaminated at similar contaminant concentrations as sediment samples that were toxic to H. azteca from other areas of the United States. The relationship between PECs and the observed toxicity was not as strong for the Microtox test. The results of this study indicate that the first phase of sediment remediation in Waukegan Harbor successfully lowered concentrations of PCBs at the site

  8. Diving Related Changes in the Blood Oxygen Stores of Rehabilitating Harbor Seal Pups (Phoca vitulina.

    Directory of Open Access Journals (Sweden)

    Amber Thomas

    Full Text Available Harbor seal (Phoca vitulina pups begin diving within hours of birth, stimulating the development of the blood oxygen (O2 stores necessary to sustain underwater aerobic metabolism. Since harbor seals experience a brief nursing period, the early-life development of these blood O2 stores is necessary for successful post-weaning foraging. If mothers and pups become prematurely separated, the pup may be transported to a wildlife rehabilitation center for care. Previous studies suggest that the shallow pools and lack of diving in rehabilitation facilities may lead to under-developed blood O2 stores, but diving behavior during rehabilitation has not been investigated. This study aimed to simultaneously study the diving behaviors and blood O2 store development of rehabilitating harbor seal pups. Standard hematology measurements (Hct, Hb, RBC, MCV, MCH, MCHC were taken to investigate O2 storage capacity and pups were equipped with time-depth recorders to investigate natural diving behavior while in rehabilitation. Linear mixed models of the data indicate that all measured blood parameters changed with age; however, when compared to literature values for wild harbor seal pups, rehabilitating pups have smaller red blood cells (RBCs that can store less hemoglobin (Hb and subsequently, less O2, potentially limiting their diving capabilities. Wild pups completed longer dives at younger ages (maximum reported <25 days of age: 9 min in previous studies than the captive pups in this study (maximum <25 days of age: 2.86 min. However, captivity may only affect the rate of development, as long duration dives were observed (maximum during rehabilitation: 13.6 min at 89 days of age. Further, this study suggests that there may be a positive relationship between RBC size and the frequency of long duration dives. Thus, rehabilitating harbor seal pups should be encouraged to make frequent, long duration dives to prepare themselves for post-release foraging.

  9. Program and Abstracts of the National Meeting of the Society for Leukocyte Biology (25th) Held in Washington, DC on October 27-30, 1988. Journal of Leukocyte Biology. Volume 44, Number 4

    Science.gov (United States)

    1988-10-01

    type 1 (E13-), bovine respiratory ’vtz-l r si at syncytial sirus (BRSV), bovine viral diarrhoea virus (BVDV) or (. 7e-~-- parainfluenza type 3 virs (P1...Annual Meeting Program POSTER SESSION I Friday, October 28th, 7:30 AM-9:3OAM GRANULOCYTE ACTIVATION Hemisphere Room 1. SELECTIVE ACTIVATION OF BOVINE ...NEUTROPHIL FUNCTIONS BY RECOMBINANT BOVINE INTERLEUKIN-l . P. Canning, National Animal Disease Center, Agricultural Research Service, U.S.D.A.,AmesTA

  10. Nonindigenous Marine Species Introductions in the harbors of the South and West Shores of Oahu, Hawaii 1997-1998 (NODC Accession 0000324)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Despite the potential importance of Honolulu Harbor or other commercial harbors on Oahu as potential gateways for nonindigenous marine species to enter the Hawaiian...

  11. Complete Sequence of Four Multidrug-Resistant MOBQ1 Plasmids Harboring blaGES-5 Isolated from Escherichia coli and Serratia marcescens Persisting in a Hospital in Canada.

    Science.gov (United States)

    Boyd, David; Taylor, Geoffrey; Fuller, Jeff; Bryce, Elizabeth; Embree, Joanne; Gravel, Denise; Katz, Kevin; Kibsey, Pamela; Kuhn, Magdalena; Langley, Joanne; Mataseje, Laura; Mitchell, Robyn; Roscoe, Diane; Simor, Andrew; Thomas, Eva; Turgeon, Nathalie; Mulvey, Michael

    2015-06-01

    The usefulness of carbapenems for gram-negative infections is becoming compromised by organisms harboring carbapenemases, enzymes which can hydrolyze the drug. Currently KPC (class A), NDM (class B), and OXA-48 types (class D) are the most globally widespread carbapenemases. However, among the GES-type class A extended-spectrum β-lactamases (ESBLs) there are variants that hydrolyze carbapenems, with blaGES-5 being the most common. Two Escherichia coli and two Serratia marcescens harboring blaGES-5 on plasmids were isolated by the Canadian Nosocomial Infection Surveillance Program (CNISP) from four different patients in a single hospital over a 2-year period. Complete sequencing of the blaGES-5 plasmids indicated that all four had nearly identical backbones consisting of genes for replication, partitioning, and stability, but contained variant accessory regions consisting of mobile elements and antimicrobial resistance genes. The plasmids were of a novel replicon type, but belonged to the MOBQ1 group based on relaxase sequences, and appeared to be mobilizable, but not self-transmissible. Considering the time periods of bacterial isolation, it would appear the blaGES-5 plasmid has persisted in an environmental niche for at least 2 years in the hospital. This has implications for infection control and clinical care when it is transferred to clinically relevant gram-negative organisms.

  12. Long distance movements and disjunct spatial use of harbor seals (Phoca vitulina in the inland waters of the Pacific Northwest.

    Directory of Open Access Journals (Sweden)

    Sarah H Peterson

    Full Text Available BACKGROUND: Worldwide, adult harbor seals (Phoca vitulina typically limit their movements and activity to 100 km from their capture site at least once, two of which traveled round trip to and from the Pacific coast, a total distance >400 km. Disjunct spatial use patterns observed provide new insight into general harbor seal behavior. CONCLUSIONS/SIGNIFICANCE: Long-distance movements and disjunct spatial use of adult harbor seals have not been reported for the study region and are rare worldwide in such a large proportion of tagged individuals. Thus, the ecological influence of individual seals may reach farther than previously assumed.

  13. Determination and assessment of phthalate esters content in sediments from Kaohsiung Harbor, Taiwan.

    Science.gov (United States)

    Chen, Chih-Feng; Chen, Chiu-Wen; Ju, Yun-Ru; Dong, Cheng-Di

    2016-12-20

    Phthalate esters (PAEs) are known organic endocrine disruptors. The distribution of 10 PAEs in sediments of Kaohsiung Harbor of Taiwan was studied using organic solvents extraction and quantified by gas chromatography/mass spectrometry. The average concentration of total PAEs (ΣPAEs) in the sediment was 8713±11,454ng/g dw with di-(2-ethylhexyl) phthalate (DEHP) (3630ng/g-dw) and diisononyl phthalate (DiNP) (3497ng/g dw) being the major species, which constitutes of 41.7% and 40.1% of ΣPAEs. PAEs concentration was relatively high near the river mouths, especially in Love River mouth, and diminished toward the harbor. Based on the sediment quality guidelines developed from previous studies, several of the observed PAE levels exceeded the Maximum Contaminant Level, especially for DEHP and thus may cause adverse effect in aquatic organisms. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal (Phoca vitulina population

    Directory of Open Access Journals (Sweden)

    Hueffer Karsten

    2013-01-01

    Full Text Available Abstract Background Brucella is a group of bacteria that causes brucellosis, which can affect population health and reproductive success in many marine mammals. We investigated the serological prevalence of antibodies against Brucella bacteria in a declining harbor seal population in Glacier Bay National Park, Alaska. Results Prevalence ranged from 16 to 74 percent for those tests detecting antibodies, indicating that harbor seals in Glacier Bay have been exposed to Brucella bacteria. However, the actual level of serological prevalence could not be determined because results were strongly assay-dependent. Conclusions This study reinforces the need to carefully consider assay choice when comparing different studies on the prevalence of anti–Brucella antibodies in pinnipeds and further highlights the need for species- or taxon-specific assay validation for both pathogen and host species.

  15. The Magic Background of Pearl Harbor. Volume 2 (May 12, 1941 - August 6, 1941)

    Science.gov (United States)

    1977-01-01

    gi rsc ­i d tv rt l dr ously.trylyd pe denciesdpr torathg.l fullti izt nt,nellatf ses ntov...American countries should also be taken into consideration, Mr. Yamagata planned to visit Panama, Colombia and Peru.442 Experiencing difficulty in...presidential decree prohibiting the entrance of submarines of belligerent powers into Peruvian waters and harbors.5O2 (e) Colombia . and according to

  16. Sakonnet Harbor, Little Compton, Rhode Island, Small Navigation Project: Detailed Project Report. Main Report & Appendices

    Science.gov (United States)

    1981-01-01

    34onrinental Shelf from the Bay of Fundy of Cape Hatteras. Center for Natural Areas, So. Gardiiier, ’AE. Section IV. 166 pp. Ippen, A.T. 1966. Estuary and...locations to unload their catch. Marine commerce now located at Sakonnet Harbor includes trap and gillnet fishing, lobstering (inshore and offshore...primarily fish for lobster , with 33 of the 45 commercial boats A.eaed fcr lobstering . The remaining vessels are a mix of power swordfish, trap, seaweed

  17. The War on Cancer: Cold Spring Harbor Laboratory Is Fighting the Good Fight.

    Science.gov (United States)

    Mertz, Leslie

    2017-01-01

    Located on the north shore of Long Island in New York, Cold Spring Harbor Laboratory (Figure 1) started out with a marine biology emphasis at the end of the 19th century, but it soon established itself as a prominent cancer research facility. That strong emphasis on cancer work continues today as this private, not-for-profit research institution enters its 127th year (Figure 2).

  18. Tier 1 ecological evaluation of proposed discharge of dredged material from Oakland Harbor into ocean waters

    Energy Technology Data Exchange (ETDEWEB)

    Shreffler, D.K.; Thorn, R.M.; Walls, B.E.; Word, J.Q. [Battelle/Marine Sciences Lab., Sequim, WA (United States)

    1994-01-01

    The Water Resources Development Act of 1986 (Public Law 99--662) authorized the U.S. Army Corps of Engineers (USACE) -- San Francisco District, to accommodate larger, deeper draft vessels in Oakland inner and Outer Harbors by deepening and widening the existing navigation channel, and providing turning basins and maneuvering areas in Oakland inner Harbor. The suitability of the resulting dredged material for disposal into ocean waters was subject to the procedures of the 1991 Testing Manual, Evaluation of Dredged Material Proposed for Ocean Disposal, known as the ``Green Book``. The Green Book provides a tiered approach for testing the suitability of dredged materials through chemical, physical, and biological evaluations. The first level of investigation, or Tier 1 evaluation, is used to determine whether a decision on LPC compliance can be made on the basis of readily available information. The Tier 1 report primarily summarizes existing information on sediment contamination and toxicity potential, identifies contaminants of concern, and determines the need for further testing. To assist the USACE in determining the suitability of dredged material from Oakland inner and Outer Harbors for ocean disposal, Battelle/Marine Sciences Laboratory prepared this Tier 1 report based upon information and data provided by USACE. Because this Tier 1 report originated well after an LPC determination was made to require testing of project sediments in Tier 3, the primary purpose of this report was to identify contaminants of concern (if any) in that particular dredged material. In addition, this Tier 1 report summarizes available information on chemical, physical, and biological characterization of the sediments in Oakland inner and Outer Harbors.

  19. Evaluation of Resuspension from Propeller Wash in DoD Harbors

    Science.gov (United States)

    2016-09-01

    Water-Effect Ratios might be appropriate. No potential for toxicity was measured for organic contaminants resuspended in San Diego Bay. Polycyclic...support of the Commander, Navy Region Southwest (CNRSW), including Mr. Brian Gordon (manager), Mr. Paul Patricio ( Port Ops Waterfront Project Manager...their associated contaminant load are lacking for Navy harbors. This study provides examples how Maynord’s model, predicting tug-boat sediment

  20. Floating-Harbor syndrome and intramedullary spinal cord ganglioglioma: case report and observations from the literature.

    Science.gov (United States)

    Nelson, Rachel A; McNamara, Michelle; Ellis, William; Stein-Wexler, Rebecca; Moghaddam, Billur; Zwerdling, Theodore

    2009-10-01

    We report on a 5-year-old male with expressive language delay, developmental delay, short stature, and facial anomalies consistent with Floating-Harbor syndrome (FHS). In addition, he developed an intramedullary ganglioglioma. This is the first reported case of a tumor associated with FHS, and may represent an as yet undefined genetic link between spinal cord tumors and FHS, adding this syndrome to the growing list of disorders with a predisposition for tumor development.

  1. Mutations in SRCAP, Encoding SNF2-Related CREBBP Activator Protein, Cause Floating-Harbor Syndrome

    OpenAIRE

    Hood, Rebecca L.; Lines, Matthew A.; Nikkel, Sarah M.; Schwartzentruber, Jeremy; Beaulieu, Chandree; Nowaczyk, Małgorzata J.M.; Allanson, Judith; Kim, Chong Ae; Wieczorek, Dagmar; Moilanen, Jukka S.; Lacombe, Didier; Gillessen-Kaesbach, Gabriele; Whiteford, Margo L.; Quaio, Caio Robledo D.C.; Gomy, Israel

    2012-01-01

    Floating-Harbor syndrome (FHS) is a rare condition characterized by short stature, delayed osseous maturation, expressive-language deficits, and a distinctive facial appearance. Occurrence is generally sporadic, although parent-to-child transmission has been reported on occasion. Employing whole-exome sequencing, we identified heterozygous truncating mutations in SRCAP in five unrelated individuals with sporadic FHS. Sanger sequencing identified mutations in SRCAP in eight more affected perso...

  2. Evaluation of Resuspension from Propeller Wash in DoD Harbors

    Science.gov (United States)

    2016-05-01

    Intermediate Maintenance Facility , Pearl Harbor, on Top. And Distribution of Contaminants of Concern in Sediments in the Area of Study in the Bottom...Intermediate maintenance Facility Kg/m2/sec Kilogram-meter per second OBS Optical Backscatter Sensor PIV Particle Image Velocimeter PSNS...section of the bay. Docking, berthing , and tugging of naval vessels within the naval piers are routine activities, which result in resuspension of

  3. Ice Harbor Spillway Dissolved Gas Field Studies: Before and After Spillway Deflectors

    Science.gov (United States)

    2016-07-01

    interior bays. The tailwater channel downstream of the stilling basin is generally above elevation 320 ft with the exception of a large depression ...generation releases. The use of remote logging TDG instruments would result in a wealth of data detailing both the spacial extent and temporal... depression located upstream of the end of the lock guide wall. 4. Hydrodynamics. The main spillway flow at Ice Harbor, plunges and moves through

  4. Effects of an oil spill in a harbor assessed using biomarkers of exposure in eelpout.

    Science.gov (United States)

    Sturve, Joachim; Balk, Lennart; Liewenborg, Birgitta; Adolfsson-Erici, Margaretha; Förlin, Lars; Carney Almroth, Bethanie

    2014-12-01

    Oil spills occur commonly, and chemical compounds originating from oil spills are widespread in the aquatic environment. In order to monitor effects of a bunker oil spill on the aquatic environment, biomarker responses were measured in eelpout (Zoarces viviparus) sampled along a gradient in Göteborg harbor where the oil spill occurred and at a reference site, 2 weeks after the oil spill. Eelpout were also exposed to the bunker oil in a laboratory study to validate field data. The results show that eelpout from the Göteborg harbor are influenced by contaminants, especially polycyclic aromatic hydrocarbons (PAHs), also during "normal" conditions. The bunker oil spill strongly enhanced the biomarker responses. Results show elevated ethoxyresorufin-O-deethylase (EROD) activities in all exposed sites, but, closest to the oil spill, the EROD activity was partly inhibited, possibly by PAHs. Elevated DNA adduct levels were also observed after the bunker oil spill. Chemical analyses of bile revealed high concentrations of PAH metabolites in the eelpout exposed to the oil, and the same PAH metabolite profile was evident both in eelpout sampled in the harbor and in the eelpout exposed to the bunker oil in the laboratory study.

  5. The Plurality of Harbors at Caesarea: The Southern Anchorage in Late Antiquity

    Science.gov (United States)

    Ratzlaff, Alexandra; Galili, Ehud; Waiman-Barak, Paula; Yasur-Landau, Assaf

    2017-08-01

    The engineering marvel of Sebastos, or Portus Augusti as it was called in Late Antiquity (284-638 CE), dominated Caesarea's harbor center along modern Israel's central coast but it was only one part of a larger maritime complex. The Southern Anchorage provides a case study as one portion of the Caesarea complex, as well as a node within the regional network of anchorages and small harbors. Ceramics recovered from here show a high percentage of locally, and provincially, produced storage jars engaged in maritime trade. The ceramic evidence points towards an intensified regional trade or cabotage rather than favouring long distance trade from large port to port. Working out of these small harbors, opportunities arose for greater flexibility in specialization of commodities and materials passing through the network of subsidiary ports, contributing to a more diversified market economy. This analysis provides another example in the growing focus on how these simple and semi-modified anchorages in the Eastern Mediterranean were often the predominant economic networks connecting hinterland and coastal trade.

  6. Evaluation of dredged material proposed for ocean Disposal from Shoal Harbor/Compton Creek Project Area

    Energy Technology Data Exchange (ETDEWEB)

    Gardiner, W.W.; Borde, A.B.; Nieukirk, S.L.; Barrows, E.S.; Gruendell, B.D.; Word, J.Q.

    1996-10-01

    The objective of the Shoal Harbor/Compton Creek Project was to evaluate proposed dredged material from the Shoal harbor/Compton Creek Project Area in Belford and Monmouth, New Jersey to determine its suitability for unconfined ocean disposal at the Mud Dump Site. This was one of five waterways that the US Army Corps of Engineers- New York District requested the Battelle Marine Sciences Laboratory (MSL) to sample and evaluate for dredging and disposal in May 1995. The evaluation of proposed dredged material from the Shoal Harbor/Compton Creek Project area consisted of bulk chemical analyses, chemical analyses of dredging site water and elutriate, benthic and water-column acute toxicity tests and bioaccumulation studies. Eleven core samples were analyzed or grain size, moisture content, and total organic carbon. Other sediments were evaluated for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congers, polynuclear aromatic hydrocarbons, and 1,4- dichlorobenzene. Dredging site water and elutriate water were analyzed for metals, pesticides, and PCBs.

  7. Treatment of Moyamoya Disease and Unruptured Intracranial Aneurysm in Floating-Harbor Syndrome.

    Science.gov (United States)

    Coughlin, Daniel J; Miller, Charles A; Schuette, A Jesse

    2017-08-01

    This is the first report of the successful treatment of moyamoya disease and an unruptured intracranial aneurysm in a patient with Floating-Harbor syndrome. A 35-year-old, phenotypically syndromic woman presented with signs and symptoms consistent with ischemic stroke. Magnetic resonance imaging and catheter angiography confirmed diagnosis of moyamoya and a 6-mm basilar apex artery aneurysm (BAA). She underwent right-sided craniotomy for direct and indirect revascularization by means of superficial temporal artery-middle cerebral artery bypass and encephalo-duro-arterio-synangiosis. Three months later, she underwent stent-assisted coiling of the BAA. At 9 months, the patient remains without her preoperative neurological deficits. Interval catheter angiography confirms revascularization of her right hemisphere and obliteration of her BAA. We present the first case of diagnosis and treatment of moyamoya disease and BAA in a patient with Floating-Harbor syndrome. Due to a paucity of literature on this rare disorder, there has not been an associated link between Floating-Harbor syndrome and cerebrovascular disease. Our report and literature review suggest that these patients may be prone to cerebrovascular disorders and should be followed closely with neurovascular imaging. Published by Elsevier Inc.

  8. Cloning and Sequencing of Protein Kinase cDNA from Harbor Seal (Phoca vitulina Lymphocytes

    Directory of Open Access Journals (Sweden)

    Jennifer C. C. Neale

    2004-01-01

    Full Text Available Protein kinases (PKs play critical roles in signal transduction and activation of lymphocytes. The identification of PK genes provides a tool for understanding mechanisms of immunotoxic xenobiotics. As part of a larger study investigating persistent organic pollutants in the harbor seal and their possible immunomodulatory actions, we sequenced harbor seal cDNA fragments encoding PKs. The procedure, using degenerate primers based on conserved motifs of human protein tyrosine kinases (PTKs, successfully amplified nine phocid PK gene fragments with high homology to human and rodent orthologs. We identified eight PTKs and one dual (serine/threonine and tyrosine kinase. Among these were several PKs important in early signaling events through the B- and T-cell receptors (FYN, LYN, ITK and SYK and a MAP kinase involved in downstream signal transduction. V-FGR, RET and DDR2 were also expressed. Sequential activation of protein kinases ultimately induces gene transcription leading to the proliferation and differentiation of lymphocytes critical to adaptive immunity. PKs are potential targets of bioactive xenobiotics, including persistent organic pollutants of the marine environment; characterization of these molecules in the harbor seal provides a foundation for further research illuminating mechanisms of action of contaminants speculated to contribute to large-scale die-offs of marine mammals via immunosuppression.

  9. Composition and source of butyltins in sediments of Kaohsiung Harbor, Taiwan

    Science.gov (United States)

    Dong, Cheng-Di; Chen, Chih-Feng; Chen, Chiu-Wen

    2015-04-01

    Fifty-eight sediment samples were collected from the Kaohsiung Harbor (Taiwan) for analyses of monobutyltin (MBT), dibutyltin (DBT) and tributyltin (TBT), using gas chromatography/flame photometric detector (GC/FPD). The concentration of total butyltins (ΣBTs), sum of MBT, DBT, and TBT, varied from 3.9 to 158.5 ng Sn/g dw in sediment samples with TBT being the major component of the sediment samples, except for the vicinity of the Love River mouth where MBT was the most abundant BT compound (a proportion of over 57%). Based on the BTs concentration, distribution, composition and correlations, the sources of BTs found in harbor sediments are shipping activities, and TBT is the main pollutant; the estuary (i.e. Love River) has been the anthropogenic source of MBT from upstream inputs. Influences of TBT on aquatic organisms are evaluated using the toxicity guidelines proposed by the US EPA (US Environmental Protection Agency) and the ACCI (assessment class criterion for imposex) proposed by OSPAR (Oslo and Paris Commission). The evaluation shows that the TBT contained in the sediment at Kaohsiung Harbor is likely to have a negative influence at ACCI class C because gastropods present imposex and TBT levels are above ecotoxicological assessment criteria (EAC) limits.

  10. Fisheries and biodiversity of the beach seine catch from the Eastern Harbor, Alexandria, Egypt

    Directory of Open Access Journals (Sweden)

    E.H.Kh. Akel

    2014-01-01

    Full Text Available In the present study, the catch of beach seine operating in the Eastern Harbor of Alexandria (Egypt during the fishing season of 2009 was investigated. Fishing is allowed all year except for some weeks in the winter. Catch efficiency was estimated to be 37.94 kg/haul and catch rate was 25.29 kg/h. The catch was classified into economic (60.24% and non-economic (39.76% species. The total number of species caught in the Eastern Harbor was 46 species (31 economic, 15 non-economic belonging to 31 families (16 economic, 15 non-economic. The economic category of species was dominated by the immigrant sardine species Herklotsichthys punctatus while the non-economic category was dominated by Engraulis encrasicolus. Eight species were lessepsian. In terms of abundance, seven species were recorded during four seasons, seven species occurred in three seasons; ten species were found in two seasons while the rest occurred in one season only. Species compositions, size composition, the length-weight relationships as well as age composition for some dominant species were investigated. Fishing in sheltered places or nursery grounds with small meshed nets (0.5 cm causes drastic danger to the fish populations of the Eastern Harbor.

  11. A Comparison of Microbial Water Quality and Diversity for Ballast and Tropical Harbor Waters.

    Directory of Open Access Journals (Sweden)

    Charmaine Ng

    Full Text Available Indicator organisms and antibiotic resistance were used as a proxy to measure microbial water quality of ballast tanks of ships, and surface waters in a tropical harbor. The survival of marine bacteria in ballast tanks appeared to diminish over longer water retention time, with a reduction of cell viability observed after a week based on heterotrophic plate counts. Pyrosequencing of 16S rRNA genes showed distinct differences in microbial composition of ballast and harbor waters. The harbor waters had a higher abundance of operational taxonomic units (OTUs assigned to Cyanobacteria (Synechococcus spp. and α-proteobacteria (SAR11 members, while marine hydrocarbon degraders such as γ-proteobacteria (Ocenspirillaes spp., Thiotrchales spp. and Bacteroidetes (Flavobacteriales spp. dominated the ballast water samples. Screening of indicator organisms found Escherichia coli (E. coli, Enterococcus and Pseudomonas aeruginosa (P. aeruginosa in two or more of the ballast and harbor water samples tested. Vibrio spp. and Salmonella spp. were detected exclusively in harbor water samples. Using quantitative PCR (qPCR, we screened for 13 antibiotic resistant gene (ARG targets and found higher abundances of sul1 (4.13-3.44 x 102 copies/mL, dfrA (0.77-1.80 x10 copies/mL and cfr (2.00-5.21 copies/mL genes compared to the other ARG targets selected for this survey. These genes encode for resistance to sulfonamides, trimethoprim and chloramphenicol-florfenicol antibiotics, which are also known to persist in sediments of aquaculture farms and coastal environments. Among the ARGs screened, we found significant correlations (P<0.05 between ereA, ermG, cfr and tetO genes to one or more of the indicator organisms detected in this study, which may suggest that these members contribute to the environmental resistome. This study provides a baseline water quality survey, quantitatively assessing indicators of antibiotic resistance, potentially pathogenic organisms and a

  12. Sediment profile image data from October 1995 in the inland bays of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment profile images (SPI) of the sediment-water interface were collected using a sediment profiling camera at pre-determined locations in the harbor. Physical,...

  13. Sediment profile image data from October 1994 in Lower Bay of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment profile images (SPI) of the sediment-water interface were collected using a sediment profiling camera at pre-determined locations in the harbor. Physical,...

  14. Sediment profile image data from June 1995 in the inland bays of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment profile images (SPI) of the sediment-water interface were collected using a sediment profiling camera at pre-determined locations in the harbor. Physical,...

  15. Sediment profile image data from June 1995 in Lower Bay of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment profile images (SPI) of the sediment-water interface were collected using a sediment profiling camera at pre-determined locations in the harbor. Physical,...

  16. Comparative account of macrofouling ecology at Vijaydurg Harbor and Musakazi-Jaitapur Bay, central western coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Sawant, S.S.; Wagh, A.B.

    The extent and the nature of fouling were studied on mild steel, aluminum, and stainless steel panels at the Vijaydurg Harbor and Musakazi-Jaitapur Bay on the central western coast of India. In addition, cathodically protected and unprotected panels...

  17. Benthic grab data from October 1995 in the inland bays of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Benthic grab samples were collected using a Shipek grab at pre-determined locations in the harbor. Taxonomic enumerations and biological community parameters were...

  18. Benthic grab data from June 1995 in the inland bays of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Benthic grab samples were collected using a Shipek grab at pre-determined locations in the harbor. Taxonomic enumerations and biological community parameters were...

  19. Selenium and mercury concentrations in harbor seals (Phoca vitulina) from central California: Health implications in an urbanized estuary

    Science.gov (United States)

    McHuron, Elizabeth A.; Harvey, James T.; Castellini, J. Margaret; Stricker, Craig A.; O'Hara, Todd M.

    2014-01-01

    We measured total selenium and total mercury concentrations ([TSe] and [THg]) in hair (n = 138) and blood (n = 73) of harbor seals (Phoca vitulina) from California to assess variation by geography and sex, and inferred feeding relationships based on carbon, nitrogen, and sulfur stable isotopes. Harbor seals from Hg-contaminated sites had significantly greater [THg], and lesser [TSe] and TSe:THg molar ratios than seals from a relatively uncontaminated site. Males had significantly greater [THg] than females at all locations. Sulfur stable isotope values explained approximately 25% of the variability in [THg], indicating increased Hg exposure for seals with a greater use of estuarine prey species. Decreased [TSe] in harbor seals from Hg-contaminated regions may indicate a relative Se deficiency to mitigate the toxic effects of Hg. Further investigation into the Se status and the potential negative impact of Hg on harbor seals from Hg-contaminated sites is warranted.

  20. Single-Beam Bathymetry Sounding Data of Charlotte Harbor and offshore Captiva Island, Florida (2003-2004) in XYZ format

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Charlotte Harbor is America's 17th largest and Florida's second largest open water estuary. It has a broad barrier island chain, large parts of which are in public...

  1. Biodiversity of marine communities in Pearl Harbor, Oahu, Hawaii with observations in 1996 on introduced exotic species (NODC Accession 0000330)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The marine and estuarine invertebrate and fish communities in Pearl Harbor, Oahu, Hawaii were surveyed between January and October, 1996. Samples were taken and...

  2. Sediment grab data from June 1995 in the inland bays of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment grab samples were collected using a Shipek grab at pre-determined locations in the harbor. Grain size distributions and organic content were measured and...

  3. Sediment grab data from October 1995 in the inland bays of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment grab samples were collected using a Shipek grab at pre-determined locations in the harbor. Grain size distributions and organic content were measured and...

  4. Sediment grab data from June 1995 in the Lower Bay of New York/New Jersey Harbor

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment grab samples were collected using a Shipek grab at pre-determined locations in the harbor. Grain size distributions and organic content were measured and...

  5. Seney National Wildlife Refuge, Harbor Islands National Wildlife Refuge, Huron Islands National Wildlife Refuge: Annual narrative report: Calendar year 1989

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Seney NWR, Huron Island NWR, and Harbor Island NWR outlines Refuge accomplishments during the 1989 calendar year. The report begins...

  6. Influenza A virus H10N7 detected in dead harbor seals (Phoca vitulina) at several locations in Denmark 2014

    DEFF Research Database (Denmark)

    Hjulsager, Charlotte Kristiane; Krog, Jesper Schak; Hansen, Mette Sif

    as many waterfowl species and are therefore potentially exposed to AIV. Outbreaks of AI in seals have been described in North America and Asia but prior to 2014 never in Europe. In 2014 massive deaths of harbor seals (Phoca vitulina) were reported in Northern Europe. In Denmark, harbor seals were...... initially found dead on the Danish island Anholt in Kattegat, which is the sea surrounded by Denmark, Norway and Sweden. Between June and August, 152 harbor seals were found dead. Four seals were submitted to the National Veterinary Institute in Dennmark and diagnosed with severe pneumonia. Influenza...... A virus of the subtype H10N7 was detected in two out of four seals. Subsequently IAV was detected in dead harbor seals at several locations in Denmark. The IAV outbreak appeared to move with time to the west through the Limfjord to the North Sea and further down south along the west coast of Jutland...

  7. Environmental assessment of proposed dredging and disposal activities at the St. George small boat harbor, reconnaissance stage: Planning aid report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Types of environmental impacts possibly resulting from dredging and disposal activities at the St. George Island small boat harbor include: 1) bottom topographic and...

  8. Seney National Wildlife Refuge, Harbor Islands National Wildlife Refuge, Huron Islands National Wildlife Refuge: Annual narrative report: Calendar year 1988

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Seney NWR, Huron Islands and Harbor Island NWR outlines Refuge accomplishments during the 1988 calendar year. The report begins with...

  9. An investigation of the feasibility of building a harbor on the West coast of South America using explosive power of nuclear weapons, a preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Zodtner, H. H.

    1971-12-31

    There is an interest in discovering the various peace time uses of nuclear explosives. One of the proposals is the building of harbors. There are several ports along the west coast of South America where lighterage is necessary. This implies a need for expanded harbor facilities. The problem is to find a good location for creating a harbor, and the feasibility of accomplishing this with the use of nuclear force. Feasibility includes blast effects, radiation hazards, the number of weapons needed, and economic considerations. Economic considerations include the cost of treating a harbor of sufficient depth and area, the building of harbor facilities, and the estimated savings and advantages of the new harbor. Several meetings were held with naval personnel of the Military Liaison group at UCRL to discuss the general problems of harbors. Thirty-three different ports were given a preliminary investigation.

  10. Falsirhodobacter sp. alg1 Harbors Single Homologs of Endo and Exo-Type Alginate Lyases Efficient for Alginate Depolymerization

    OpenAIRE

    Mori, Tetsushi; Takahashi, Mami; Tanaka, Reiji; Miyake, Hideo; Shibata, Toshiyuki; Chow, Seinen; Kuroda, Kouichi; Ueda, Mitsuyoshi; Takeyama, Haruko

    2016-01-01

    Alginate-degrading bacteria play an important role in alginate degradation by harboring highly efficient and unique alginolytic genes. Although the general mechanism for alginate degradation by these bacteria is fairly understood, much is still required to fully exploit them. Here, we report the isolation of a novel strain, Falsirhodobacter sp. alg1, the first report for an alginate-degrading bacterium from the family Rhodobacteraceae. Genome sequencing reveals that strain alg1 harbors a prim...

  11. 78 FR 23489 - Safety Zone; V.I. Carnival Finale, St. Thomas Harbor; St. Thomas, U.S.V.I.

    Science.gov (United States)

    2013-04-19

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; V.I. Carnival Finale, St. Thomas Harbor; St. Thomas, U.S.V.I. AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a safety zone on the waters of St. Thomas Harbor in St. Thomas, U.S. Virgin Islands during the V.I...

  12. Interim Feasibility Report and Draft Environmental Impact Statement, Grays Harbor, Chehalis and Hoquiam Rivers, Washington, Channel Improvements for Navigation.

    Science.gov (United States)

    1982-06-01

    community depends on the continued descent of organic materials from the overlying waters for nourishment. The Dungeness crab ( Cancer magister) is an...immediately north and south of Grays Harbor. EIS-34 o Crabs. Dungeness crabs ( Cancer magister) are abundant in Grays Harbor, though most are smaller...Cooper Cultural Resources Mama Seattle District, Evaluation Corps of Engineers Endangered Species Brunner Seattle District, Evaluation Corps of Engineers

  13. Assessment of a combination between hard structures and sand nourishment eastern of Damietta harbor using numerical modeling

    Directory of Open Access Journals (Sweden)

    A.M. Khalifa

    2017-12-01

    Full Text Available Damietta harbor was constructed in 1982 as an inland harbor with its 15 m depth navigation channel and two jetties acting like an obstacle to not allow sediment deposition in the harbor. On the other hand, they significantly affect the northern coast shoreline and hinder the sediment circulation in Damietta promontory. Satellite images show that new headlands are being implemented in the coastal shores of As-senaneyah. The proposed project consists of implementation of four headlands with length of 160 m, spacing of 400 m and using 150,000 m3 nourishment in those spacing between the hard structures only once during the construction time. Litpack 1D-model is used to predict shoreline responses to number of different five scenarios considered as combination between hard structures such as headlands and sand nourishment. A total number of 32 profiles were used to assess the shoreline changes along Gamasa, Damietta and Ras El-bar resort from 2010 to 2015. This study prevails a high erosion rate of the eastern and western shorelines of the proposed headlands. Nourishment of 200,000 m3/year is found to be a reasonable solution due to simplicity of being attained from Damietta harbor’s annual dredged materials which was reported to be average of 1 million m3/year. Keywords: Numerical modeling, Damietta harbor, Egyptian shoreline changes, Inland harbor

  14. New insights into the diets of harbor seals in the Salish Sea revealed by quantitative fatty acid signature analysis

    Science.gov (United States)

    Bromaghin, Jeffrey F.; Lance, Monique M.; Elliott, Elizabeth W.; Jeffries, Steven J.; Acevedo-Gutiérrez, Alejandro; Kennish, John M.

    2012-01-01

    Harbor seals (Phoca vitulina) are an abundant predator along the west coast of North America, and there is considerable interest in their diet composition, especially in regard to predation on valued fish stocks. Available information on harbor seal diets, primarily derived from scat analysis, suggests that adult salmon (Oncorhynchus spp.), Pacific Herring (Clupea pallasii), and gadids predominate. Because diet assessments based on scat analysis may be biased, we investigated diet composition through quantitative analysis of fatty acid signatures. Blubber samples from 49 harbor seals captured in western North America from haul-outs within the area of the San Juan Islands and southern Strait of Georgia in the Salish Sea were analyzed for fatty acid composition, along with 269 fish and squid specimens representing 27 potential prey classes. Diet estimates varied spatially, demographically, and among individual harbor seals. Findings confirmed the prevalence of previously identified prey species in harbor seal diets, but other species also contributed significantly. In particular, Black (Sebastes melanops) and Yellowtail (S. flavidus) Rockfish were estimated to compose up to 50% of some individual seal diets. Specialization and high predation rates on Black and Yellowtail Rockfish by a subset of harbor seals may play a role in the population dynamics of these regional rockfish stocks that is greater than previously realized.

  15. Behavior associated with forced copulation of juvenile Pacific harbor seals (Phoca vitulina richardsi) by southern sea otters (Enhydra lutris nereis)

    Science.gov (United States)

    Harris, Heather S.; Oates, Stori C.; Staedler, Michelle M.; Tinker, M. Tim; Jessup, David A.; Harvey, James T.; Miller, Melissa A.

    2010-01-01

    Nineteen occurrences of interspecific sexual behavior between male southern sea otters (Enhydra lutris nereis) and juvenile Pacific harbor seals (Phoca vitulina richardsi) were reported in Monterey Bay, California, between 2000 and 2002. At least three different male sea otters were observed harassing, dragging, guarding, and copulating with harbor seals for up to 7 d postmortem. Carcasses of 15 juvenile harbor seals were recovered, and seven were necropsied in detail by a veterinary pathologist. Necropsy findings from two female sea otters that were recovered dead from male sea otters exhibiting similar behavior are also presented to facilitate a comparison of lesions. The most frequent lesions included superficial skin lacerations; hemorrhage around the nose, eyes, flippers, and perineum; and traumatic corneal erosions or ulcers. The harbor seals sustained severe genital trauma, ranging from vaginal perforation to vagino-cervical transection, and colorectal perforations as a result of penile penetration. One harbor seal developed severe pneumoperitoneum subsequent to vaginal perforation, which was also observed in both female sea otters and has been reported as a postcoital lesion in humans. This study represents the first description of lesions resulting from forced copulation of harbor seals by sea otters and is also the first report of pneu-moperitoneum secondary to forced copulation in a nonhuman animal. Possible explanations for this behavior are discussed in the context of sea otter biology and population demographics.

  16. Receiving beam patterns in the horizontal plane of a harbor porpoise (Phocoena phocoena)

    Science.gov (United States)

    Kastelein, Ronald A.; Janssen, Mirjam; Verboom, Willem C.; de Haan, Dick

    2005-08-01

    Receiving beam patterns of a harbor porpoise were measured in the horizontal plane, using narrow-band frequency modulated signals with center frequencies of 16, 64, and 100 kHz. Total signal duration was 1000 ms, including a 200 ms rise time and 300 ms fall time. The harbor porpoise was trained to participate in a psychophysical test and stationed itself horizontally in a specific direction in the center of a 16-m-diameter circle consisting of 16 equally-spaced underwater transducers. The animal's head and the transducers were in the same horizontal plane, 1.5 m below the water surface. The go/no-go response paradigm was used; the animal left the listening station when it heard a sound signal. The method of constants was applied. For each transducer the 50% detection threshold amplitude was determined in 16 trials per amplitude, for each of the three frequencies. The beam patterns were not symmetrical with respect to the midline of the animal's body, but had a deflection of 3-7° to the right. The receiving beam pattern narrowed with increasing frequency. Assuming that the pattern is rotation-symmetrical according to an average of the horizontal beam pattern halves, the receiving directivity indices are 4.3 at 16 kHz, 6.0 at 64 kHz, and 11.7 dB at 100 kHz. The receiving directivity indices of the porpoise were lower than those measured for bottlenose dolphins. This means that harbor porpoises have wider receiving beam patterns than bottlenose dolphins for the same frequencies. Directivity of hearing improves the signal-to-noise ratio and thus is a tool for a better detection of certain signals in a given ambient noise condition.

  17. NifH- Harboring Bacterial Community Composition Across an Alaskan Permafrost Thaw Gradient

    Directory of Open Access Journals (Sweden)

    Christopher Ryan Penton

    2016-11-01

    Full Text Available Since nitrogen (N is often limiting in permafrost soils, we investigated the N2-fixing genetic potential and the inferred taxa harboring those genes by sequencing nifH gene fragments in samples taken along a permafrost thaw gradient in an Alaskan boreal soil. Samples from minimally, moderately and extensively thawed sites were taken to a depth of 79 cm to encompass zones above and below the depth of the water table. NifH reads were translated with frameshift correction and 112,476 sequences were clustered at 5% amino acid dissimilarity resulting in 1,631 OTUs. Sample depth in relation to water table depth was correlated to differences in the NifH sequence classes. NifH sequences most closely related to group I nifH-harboring Alpha- and Beta Proteobacteria were in higher abundance above water table depth while those related to group III nifH-harboring Delta and Gamma Proteobacteria were more abundant below. The most dominant below water table depth NifH sequences, comprising 1/3 of the total, were distantly related to Verrucomicrobia-Opitutaceae. Overall, these results suggest that permafrost thaw alters the class-level composition of N2-fixing communities in the thawed soil layers and that this distinction corresponds to the depth of the water table. These nifH data were also compared to nifH sequences obtained from a study at an Alaskan taiga site, and to those of other geographically distant, non-permafrost sites. The two Alaska sites were differentiated largely by changes in relative abundances of the same OTUs, whereas the non-Alaska sites were differentiated by the lack of many Alaskan OTUs, and the presence of unique halophilic, sulfate- and iron-reducing taxa in the Alaska sites.

  18. Floating-Harbor syndrome and polycystic kidneys associated with SRCAP mutation.

    Science.gov (United States)

    Reschen, Michael; Kini, Usha; Hood, Rebecca L; Boycott, Kym M; Hurst, Jane; O'Callaghan, Christopher A

    2012-12-01

    Floating-Harbor syndrome (FHS) is a rare genetic disorder recently shown to be caused by mutations in the Snf2-related CREB-binding protein activator protein gene (SRCAP). It comprises three key clinical features of characteristic facies, expressive and receptive speech impairment and short stature. We report on a patient with this syndrome associated with early adult-onset hypertension and bilateral polycystic kidneys. Family screening for polycystic kidney disease was negative and mutations in polycystic kidney disease 1 and 2 genes (PKD1 and PKD2) were absent. Sequencing of the SRCAP gene demonstrated a de novo mutation matching one of the known FHS-associated mutations. The patient required treatment with anti-hypertensives and will require lifelong renal monitoring. We suggest this patient's presentation may be due to the pleiotropic effects of SRCAP mutations. Further, the protein encoded by SRCAP is known to interact with CREB-binding protein, the product of the gene mutated in Rubinstein-Taybi syndrome, which is associated with renal abnormalities. A literature review of the renal findings in patients with Floating-Harbor syndrome identified another patient with possible polycystic kidneys, two patients with early onset hypertension, and a young patient with a ruptured intracranial aneurysm, which can be a feature of classic adult polycystic kidney disease. Collectively, these findings suggest that all patients with Floating-Harbor syndrome should undergo regular blood pressure monitoring and screening for polycystic kidneys by ultrasound at the time of the FHS diagnosis with imaging to be repeated during adulthood if a childhood ultrasound was negative. Copyright © 2012 Wiley Periodicals, Inc.

  19. Investigation of Soil Nutrients in Juicy Peach Orchards in the Watershed of Zhihu Harbor, China

    Directory of Open Access Journals (Sweden)

    LIU Zhi-guang

    2016-11-01

    Full Text Available In order to evaluate soil fertility and guide scientific fertilization in juicy peach orchards in Zhihu Harbor watershed of Tai Lake region, soil samples in four towns were collected for the analysis of soil physical and chemical properties. The results showed that soil acidification existed in 88.0% of research area in the watershed of Zhihu Harbor with pH from 3.4 to 5.4 and strong soil acidification was over 33.7%. The average value of electrical conductivity in plow layer soils was 317.6 μS·cm-1 with the variable coefficient at 63.40%, and it was above the critical value of plant inbreed electrical conductivity barrier in 11.7% of the research area. The soil clay content increased with the soil depth. 66.7% silt loam was in the plow layer soil in total cultivated area. Similar clay soil in 20~60 cm soil layer affected the penetrations of root and leakage water. The average value of soil organic matter, total nitrogen, total phosphorus, available phosphorus, and available potassium in the plow layer soil were 37.7, 2.5, 0.6, 0.3 g·kg-1 and 0.6 g·kg-1, respectively. In addition, 40.7%, 75.8%, 13.7%, 92.3% and 90.4% of research area were above the value of highest soil fertility standard in the 2nd National Soil Survey for soil organic matter, total nitrogen, total phosphorus, available phosphorus, and available potassium, respectively. It is necessary to develop special controlled release compound fertilizers, and to apply organic fertilizers with a deeper application to reduce the risk of eutrophication pollution and soil acidification while maintaining the fruit production in peach orchards in the watershed of Zhihu Harbor.

  20. Influenza A (H10N7 Virus Causes Respiratory Tract Disease in Harbor Seals and Ferrets.

    Directory of Open Access Journals (Sweden)

    Judith M A van den Brand

    Full Text Available Avian influenza viruses sporadically cross the species barrier to mammals, including humans, in which they may cause epidemic disease. Recently such an epidemic occurred due to the emergence of avian influenza virus of the subtype H10N7 (Seal/H10N7 in harbor seals (Phoca vitulina. This epidemic caused high mortality in seals along the north-west coast of Europe and represented a potential risk for human health. To characterize the spectrum of lesions and to identify the target cells and viral distribution, findings in 16 harbor seals spontaneously infected with Seal/H10N7 are described. The seals had respiratory tract inflammation extending from the nasal cavity to bronchi associated with intralesional virus antigen in respiratory epithelial cells. Virus infection was restricted to the respiratory tract. The fatal outcome of the viral infection in seals was most likely caused by secondary bacterial infections. To investigate the pathogenic potential of H10N7 infection for humans, we inoculated the seal virus intratracheally into six ferrets and performed pathological and virological analyses at 3 and 7 days post inoculation. These experimentally inoculated ferrets displayed mild clinical signs, virus excretion from the pharynx and respiratory tract inflammation extending from bronchi to alveoli that was associated with virus antigen expression exclusively in the respiratory epithelium. Virus was isolated only from the respiratory tract. In conclusion, Seal/H10N7 infection in naturally infected harbor seals and experimentally infected ferrets shows that respiratory epithelial cells are the permissive cells for viral replication. Fatal outcome in seals was caused by secondary bacterial pneumonia similar to that in fatal human cases during influenza pandemics. Productive infection of ferrets indicates that seal/H10N7 may possess a zoonotic potential. This outbreak of LPAI from wild birds to seals demonstrates the risk of such occasions for mammals

  1. Locks Restaurant Friday and Saturday Lunch Menu 2017

    OpenAIRE

    Locks

    2017-01-01

    Introducing Locks 1 Windsor Terrace, bringing the best in modern Irish food to a much loved venue in Dublin 8. Our goal here is to warmly welcome our guests into one of Dublin’s best dining rooms with an exciting and constantly evolving menu, extensive wine & bar list, great music and laid-back atmosphere. We want our customers to come back to us time and time again for both the big and small events in their lives. Upstairs we have beautiful private rooms perfect for parties, and our Head Che...

  2. “There is usually just one Friday a week”

    DEFF Research Database (Denmark)

    Gram, Malene; Grønhøj, Alice

    2015-01-01

    Parents’ knowledge of what constitutes a “healthy” diet does not always translate into action. This is often commented on as both worrying and paradoxical. This study explores how families categorize and make rules for “unhealthy” eating, particularly candy, and how these rules are sometimes bent...... policies, and in the eyes of these parents, “healthy” food is not just about nutrition, but also about social and emotional health....

  3. Friday off”: Reducing Working Hours in Europe

    Directory of Open Access Journals (Sweden)

    Jack Rossiter

    2013-04-01

    Full Text Available This article explores the pros and cons for reducing working hours in Europe. To arrive to an informed judgment we review critically the theoretical and empirical literature, mostly from economics, concerning the relation between working hours on the one hand, and productivity, employment, quality of life, and the environment, on the other. We adopt a binary economics distinction between capital and labor productiveness, and are concerned with how working hours may be reduced without harming the earning capacity of workers. There are reasons to believe that reducing working hours may absorb some unemployment, especially in the short-run, even if less than what is advocated by proponents of the proposal. Further, there may well be strong benefits for the quality of peoples’ lives. Environmental benefits are likely but depend crucially on complementary policies or social conditions that will ensure that the time liberated will not be directed to resource-intensive or environmentally harmful consumption. It is questionable whether reduced working hours are sustainable in the long-term given resource limits and climate change. We conclude that while the results of reducing working hours are uncertain, this may be a risk worth taking, especially as an interim measure that may relieve unemployment while other necessary structural changes are instituted.

  4. Prevalence of skull pathologies in European harbor seals (Phoca vitulina) during 1981–2014

    DEFF Research Database (Denmark)

    Pertoldi, Cino; Jensen, Lasse Fast; Alstrup, Aage Kristian Olsen

    2018-01-01

    Harbor seals (Phoca vitulina) inhabit the seas surrounding Denmark and are an important top predator in the marine food chain. This trophic position exposes them to environmental contaminants with disease epidemics and hunting being additional threats to this population. It is therefore important...... to the skulls with one or more of the lesions. A discriminant analysis allowed high discriminatory capacity to separate healthy skulls from the skulls with pathologies, simply by the utilization of the HU data. Former studies of BMD in marine mammals have shown that exposure to environmental chemicals alter BMD...

  5. Preliminary Feasibility Report (Stage 2), Review of Reports on Lorain Harbor, Ohio. Volume 2. Appendices. Revision

    Science.gov (United States)

    1981-05-01

    Harbor, OH Vessel M : Kid -Summer : Capacity at Name : Length t Beamr Draft : NlJ-Summer: f(ft.) RtM (ft.) 6i. Gemini : 430 : 65 23𔃺" 75,000 Jupiter : 390...bulk Freighters Operating in 1979 :Approximate Year : Kid -Su-mer Class 4esgnet.on Vessel Nae :Dimensions Built V/ _capacity 5 .- ’ 6 7 . 8 _/ "B. F...grosbeak cSR Indigo bunting cSR Evening grosbeak uW i Purple finch M-S-W Comnmon redpoll uW American goldfinch cSR-W Rufcus-sided towhee cSR-W SPARROWS

  6. A further report on a case of Floating-Harbor Syndrome in a mother and daughter.

    Science.gov (United States)

    Rosen, A C; Newby, R F; Sauer, C M; Lacey, T; Hammeke, T A; Lubinsky, M S

    1998-08-01

    We present the most extensive neuropsychological and language assessment yet reported of patients diagnosed with Floating-Harbor Syndrome (FHS), a rare genetic condition characterized by dysmorphid figures, short stature, and speech-onset delay. This is also the second reported occurrence of both a mother and daughter with FHS. Whereas the child demonstrated gross deficits in verbal expression, speech and language problems were largely ameliorated in the mother. Neuropsychological assessment also revealed a strikingly similar pattern of cognitive problems additional to language dysfunction, including difficulties with attention, mathematical, and visuospatial abilities. A mood disorder continued to be quite disabling for the mother.

  7. Chiari I malformation as part of the Floating-Harbor syndrome?

    Science.gov (United States)

    Kurzbuch, Arthur R; Magdum, Shailendra

    2016-12-01

    We report the first case of a patient diagnosed with Floating-Harbor syndrome (FHS) and Chiari I malformation. The 3-year-old girl was of proportional short stature, had delay of language development, conductive hearing loss and a high threshold of pain. Diagnosis of Chiari I malformation may be difficult in FHS patients who present with communication problems. Clinicians following patients with FHS should be aware of a possible relation between FHS and Chiari I malformation. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  8. Waterborne Commerce of the United States, Calendar Year 1985. Part 3. Waterways and Harbors. Great Lakes.

    Science.gov (United States)

    1987-05-01

    IF AIVTA. CO9TROLLI9O 890 PROJECT 0EPTI4S£ 25 FEET 19 ESTRASCE C.SA9SEL5 21.23 PEEl £5 ToE TJASTID 901195 01 FEET 19 TOE 0I£E4 C9A9SEL TO RA8YLA9O...2478 115 1ER TI TNE JPvE0 0414102 L14173, 21 FEET: tjvsJ,; dASIN, 29 PEEl . V,46APAT11E STATEMENTIF 0 14 1 YEAR TONS 3954 TONS .......... 2902...60. HI Stoeport, With. ----------------- 50. 77 ontanagon Harbor, ich.-------- ---------- 49, 76 Sturgeon Hay and Lube Michigan Ship Mango Harbar

  9. Assessing effects of PCB exposure on American mink (Mustela vison) abundance in Portland Harbor.

    Science.gov (United States)

    Luxon, Matt; Toll, John; Hanson, Craig

    2014-01-01

    This article presents an integrated analysis using a Monte Carlo exposure model, dose–response effects model and habitat,and population dynamics models, all of which allow us to quantitatively estimate the effects of polychlorinated biphenyl (PCB)exposure on American mink (Mustela vison) abundance at the Portland Harbor Superfund Site (Site), and the associated uncertainties. The Site extends from river mile 1.9 of the Lower Willamette River, near its confluence with the Columbia River, to river mile 11.8, just downstream of downtown Portland, Oregon. The potential effects of PCBs on the American mink population were evaluated in the Baseline Ecological Risk Assessment (BERA) due to the historical presence of mink in the are a and because mink are known to be highly sensitive to the effects of PCBs. Hazard quotients (HQs) calculated in the BERA indicated that PCB concentrations measured in Portland Harbor fish were above levels known to cause reproductive effects in mink. Further analysis was needed to evaluate the potential magnitude of effects on the Site mink population. The integrated analysis presented herein demonstrates that if an effect of PCB exposure is a less than 30% reduction in kit production, then PCB remediation is not expected to have any effect on mink abundance. This is a Site‐specific conclusion that depends on the quality, abundance, and distribution of mink habitat in Portland Harbor. The PCB dose associated with a 30% reduction in kit production was calculated as 101 mg/kg bw/d (90% CI ¼ 69–146 mg/kg bw/d). The mink PCB dose estimates from the Portland Harbor BERA indicate that if mink are present, their baseline exposure levels probably exceed 101 mg/kg bw/d. Therefore, some level of reduction in PCB exposure could be beneficial to the species if the study area provides sufficient habitat to support a mink population. This analysis demonstrates that risk analysis for population‐level assessment endpoints benefits from analyses

  10. Program Manager, the Journal of the Defense Systems Management College, Volume 14, Number 5, September-October 1985.

    Science.gov (United States)

    1985-10-01

    Con- of an uncontrolled government. The - Honore ’ Balzac gress to "raise an army" and to "pro- legacy, however, is a very complex en- vide and...America. do hereby proclaim Friday. July 19. 1985, as National PO W./M.I A. Recognition Day. I call on all Americans to join in honoring all former...Participation in .ive tion Day’ po4er.’ the Vietnam unknown, the President public awareness programs is one way said, "One way to honor those who we can all help

  11. 33 CFR Appendix A to Part 273 - Aquatic Plant Control Program Legislative Authority

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Aquatic Plant Control Program... OF THE ARMY, DEPARTMENT OF DEFENSE AQUATIC PLANT CONTROL Pt. 273, App. A Appendix A to Part 273—Aquatic Plant Control Program Legislative Authority Section 104 of the Rivers and Harbors Act, approved 3...

  12. Utilization of Savannah Harbor river sediment as the primary raw material in production of fired brick.

    Science.gov (United States)

    Mezencevova, Andrea; Yeboah, Nortey N; Burns, Susan E; Kahn, Lawrence F; Kurtis, Kimberly E

    2012-12-30

    A laboratory-scale study was conducted to assess the feasibility of the production of fired bricks from sediments dredged from the Savannah Harbor (Savannah, GA, USA). The dredged sediment was used as the sole raw material, or as a 50% replacement for natural brick-making clay. Sediment bricks were prepared using the stiff mud extrusion process from raw mixes consisted of 100% dredged sediment, or 50% dredged sediment and 50% brick clay. The bricks were fired at temperatures between 900 and 1000 °C. Physical and mechanical properties of the dredged sediment brick were found to generally comply with ASTM criteria for building brick. Water absorption of the dredged sediment bricks was in compliance with the criteria for brick graded for severe (SW) or moderate (MW) weathering. Compressive strength of 100% dredged sediment bricks ranged from 8.3 to 11.7 MPa; the bricks sintered at 1000 °C met the requirements for negligible weathering (NW) building brick. Mixing the dredged sediment with natural clay resulted in an increase of the compressive strength. The compressive strength of the sediment-clay bricks fired at 1000 °C was 29.4 MPa, thus meeting the ASTM requirements for the SW grade building brick. Results of this study demonstrate that production of fired bricks is a promising and achievable productive reuse alternative for Savannah Harbor dredged sediments. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Surveillance for zoonotic and selected pathogens in harbor seals Phoca vitulina from central California

    Science.gov (United States)

    Greig, Denise J.; Ip, Hon S.; Gulland, Frances M. D.; Miller, Woutrina A.; Conrad, Patricia A.; Field, Cara L.; Fleetwood, Michelle; Harvey, James T.; Jang, Spencer; Packham, Andrea; Wheeler, Elizabeth; Hall, Ailsa J.

    2014-01-01

    The infection status of harbor seals Phoca vitulina in central California, USA, was evaluated through broad surveillance for pathogens in stranded and wild-caught animals from 2001 to 2008, with most samples collected in 2007 and 2008. Stranded animals from Mendocino County to San Luis Obispo County were sampled at a rehabilitation facility: The Marine Mammal Center (TMMC, n = 175); wild-caught animals were sampled at 2 locations: San Francisco Bay (SF, n = 78) and Tomales Bay (TB, n = 97), that differed in degree of urbanization. Low prevalences of Salmonella, Campylobacter, Giardia, and Cryptosporidium were detected in the feces of stranded and wild-caught seals. Clostridium perfringens and Escherichia coli were more prevalent in the feces of stranded (58% [78 out of 135] and 76% [102 out of 135]) than wild-caught (42% [45 out of 106] and 66% [68 out of 106]) seals, whereas Vibrio spp. were 16 times more likely to be cultured from the feces of seals from SF than TB or TMMC (p virus, although a single low titer to canine distemper virus was detected. These results highlight the role of harbor seals as sentinel species for zoonotic and terrestrial pathogens in the marine environment.

  14. Sponge mass mortalities in a warming Mediterranean Sea: are cyanobacteria-harboring species worse off?

    Directory of Open Access Journals (Sweden)

    Emma Cebrian

    Full Text Available Mass mortality events are increasing dramatically in all coastal marine environments. Determining the underlying causes of mass mortality events has proven difficult in the past because of the lack of prior quantitative data on populations and environmental variables. Four-year surveys of two shallow-water sponge species, Ircinia fasciculata and Sarcotragus spinosulum, were carried out in the western Mediterranean Sea. These surveys provided evidence of two severe sponge die-offs (total mortality ranging from 80 to 95% of specimens occurring in the summers of 2008 and 2009. These events primarily affected I. fasciculata, which hosts both phototrophic and heterotrophic microsymbionts, while they did not affect S. spinosulum, which harbors only heterotrophic bacteria. We observed a significant positive correlation between the percentage of injured I. fasciculata specimens and exposure time to elevated temperature conditions in all populations, suggesting a key role of temperature in triggering mortality events. A comparative ultrastructural study of injured and healthy I. fasciculata specimens showed that cyanobacteria disappeared from injured specimens, which suggests that cyanobacterial decay could be involved in I. fasciculata mortality. A laboratory experiment confirmed that the cyanobacteria harbored by I. fasciculata displayed a significant reduction in photosynthetic efficiency in the highest temperature treatment. The sponge disease reported here led to a severe decrease in the abundance of the surveyed populations. It represents one of the most dramatic mass mortality events to date in the Mediterranean Sea.

  15. Emergence of Acinetobacter pittii harboring New Delhi metallo-beta-lactamase genes in Daejeon, Korea.

    Science.gov (United States)

    Sung, Ji Youn; Koo, Sun Hoe; Kim, Semi; Kwon, Gye Cheol

    2015-09-01

    Carbapenemase production has been reported worldwide in gram-negative bacteria, including Acinetobacter species. We detected carbapenemase-producing Acinetobacter pittii in clinical isolates in Daejeon, Korea. Twenty-one ertapenem-resistant A. pittii isolates screened with a disk diffusion method were characterized by using the Epsilon test, four multiplex PCR assays, and a multilocus sequence typing (MLST) scheme. A total of 21 A. pittii isolates harbored the metallo-β-lactamase (MBL) gene bla(IMP-1) or bla(NDM-1). Nineteen isolates containing bla(IMP-1) were resistant to imipenem and meropenem, but two isolates harboring bla(NDM-1) were susceptible to them. The sequence types (STs) of the two New Delhi MBL (NDM-1)-producing A. pittii isolates were ST70 and ST207, which differed from the STs (ST63, ST119, ST396, and a novel ST) of the IMP-1-producing A. pittii. This is the first report on NDM-1-producing A. pittii isolates in Korea. Our results emphasize that the study of NDM-1-producing gram-negative bacteria should involve carbapenem-susceptible as well as carbapenem-resistant isolates.

  16. Seasonal Variation of Harbor Seal's Diet from the Wadden Sea in Relation to Prey Availability.

    Directory of Open Access Journals (Sweden)

    Camille de la Vega

    Full Text Available The Wadden Sea has an important role for marine mammals in terms of resting, nursing and foraging. Harbor seal is the most abundant marine mammal species in this area. The use of the food resources of the Wadden Sea by seals is not clear, and previous studies showed that this species can travel kilometers away from their haul-outs to forage in the North Sea. In this study, we analyzed the stable isotopes of vibrissae from 23 dead harbor seals found on the island of Sylt to investigate their diet. The predator´s carbon and nitrogen isotope compositions were compared to the compositions of different potential prey items from the Sylt-Rømø Bight and from the North Sea in order to study seasonal pattern in the diet and in the foraging location. In parallel, seasonal variation of abundance and biomass of the potential prey items from the Sylt-Rømø Bight were studied and compare to their contribution to the seal´s diet. The results revealed a change in the seal´s diet from pelagic sources in spring to a benthic based diet in summer, and an increasing use of the North Sea resources in fall and winter in accordance with the seasonal variation of the availability of prey in the Sylt-Rømø Bight.

  17. High tributyltin and imposex levels in the commercial muricid Thais chocolata from two Peruvian harbor areas.

    Science.gov (United States)

    Castro, Ítalo Braga; Fillmann, Gilberto

    2012-05-01

    The first appraisal of butyltin (BT) contamination linked with imposex incidence in Peruvian coastal areas was performed in the present study. Imposex occurrence and BT levels in female bodies were analyzed in the rock snail Thais chocolata distributed along 10 sites in areas under the influence of Callao and Chimbote Harbors. Imposex levels associated to high tributyltin (TBT) concentrations were observed in six of 10 studied sites, and the highest imposex levels were seen in gastropods collected near the harbor terminals. Tributyltin concentrations were the highest reported for gastropod mollusks (up to 662 ng Sn g(-1)) in recent studies. Although TBT-based antifouling paints have been banned globally (International Maritime Organization, 2008), the combination of high imposex and TBTs level with butyltin degradation index values indicated fresh TBT inputs in these Peruvian coastal areas. Thus, the need to implement local regulatory strategies related to the use of TBT-free antifouling paints is urgent, as is a thorough assessment of the effectiveness of the TBT global ban. Moreover, the wide distribution of T. chocolata combined with its capability to elicit imposex and bioaccumulate BTs renders this a good sentinel species for TBT contamination along the western South American coast. Copyright © 2012 SETAC.

  18. Novel B19-like parvovirus in the brain of a harbor seal.

    Directory of Open Access Journals (Sweden)

    Rogier Bodewes

    Full Text Available Using random PCR in combination with next-generation sequencing, a novel parvovirus was detected in the brain of a young harbor seal (Phoca vitulina with chronic non-suppurative meningo-encephalitis that was rehabilitated at the Seal Rehabilitation and Research Centre (SRRC in the Netherlands. In addition, two novel viruses belonging to the family Anelloviridae were detected in the lungs of this animal. Phylogenetic analysis of the coding sequence of the novel parvovirus, tentatively called Seal parvovirus, indicated that this virus belonged to the genus Erythrovirus, to which human parvovirus B19 also belongs. Although no other seals with similar signs were rehabilitated in SRRC in recent years, a prevalence study of tissues of seals from the same area collected in the period 2008-2012 indicated that the Seal parvovirus has circulated in the harbor seal population at least since 2008. The presence of the Seal parvovirus in the brain was confirmed by real-time PCR and in vitro replication. Using in situ hybridization, we showed for the first time that a parvovirus of the genus Erythrovirus was present in the Virchow-Robin space and in cerebral parenchyma adjacent to the meninges. These findings showed that a parvovirus of the genus Erythrovirus can be involved in central nervous system infection and inflammation, as has also been suspected but not proven for human parvovirus B19 infection.

  19. Dungeness crab survey for the Southwest Ocean Disposal Site off Grays Harbor, Washington, June 1990

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, B.J.; Pearson, W.H. (Battelle/Marine Sciences Lab., Sequim, WA (United States))

    1991-09-01

    As part of the Grays Harbor Navigation Improvement Project, the Seattle District of the US Army Corps of Engineers has begun active use of the Southwest Ocean Disposal Site off Grays Harbor, Washington. This survey was to verify that the location of the area of high crab density observed during site selection surveys has not shifted into the Southeast Ocean Disposal Site. In June 1990, mean densities of juvenile Dungeness crab were 146 crab/ha within the disposal site and 609 crab/ha outside ad north of the disposal site. At nearshore locations outside the disposal site, juvenile crab density was 3275 crab/ha. Despite the low overall abundance, the spatial distribution of crab was such that the high crab densities in 1990 have remained outside the Southwest Ocean Disposal Site. The survey data have confirmed the appropriateness of the initial selection of the disposal site boundaries and indicated no need to move to the second monitoring tier. 8 refs., 9 figs., 2 tabs.

  20. Feeding Kinematics, Suction, and Hydraulic Jetting Performance of Harbor Seals (Phoca vitulina)

    Science.gov (United States)

    Marshall, Christopher D.; Wieskotten, Sven; Hanke, Wolf; Hanke, Frederike D.; Marsh, Alyssa; Kot, Brian; Dehnhardt, Guido

    2014-01-01

    The feeding kinematics, suction and hydraulic jetting capabilities of captive harbor seals (Phoca vitulina) were characterized during controlled feeding trials. Feeding trials were conducted using a feeding apparatus that allowed a choice between biting and suction, but also presented food that could be ingested only by suction. Subambient pressure exerted during suction feeding behaviors was directly measured using pressure transducers. The mean feeding cycle duration for suction-feeding events was significantly shorter (0.15±0.09 s; Psuction and a biting feeding mode. Suction was the favored feeding mode (84% of all feeding events) compared to biting, but biting comprised 16% of feeding events. In addition, seals occasionally alternated suction with hydraulic jetting, or used hydraulic jetting independently, to remove fish from the apparatus. Suction and biting feeding modes were kinematically distinct regardless of feeding location (in-water vs. on-land). Suction was characterized by a significantly smaller gape (1.3±0.23 cm; PSuction and hydraulic jetting where employed 90.5% and 9.5%, respectively, during underwater feeding events. Harbor seals displayed a wide repertoire of behaviorally flexible feeding strategies to ingest fish from the feeding apparatus. Such flexibility of feeding strategies and biomechanics likely forms the basis of their opportunistic, generalized feeding ecology and concomitant breadth of diet. PMID:24475170

  1. Human case of bacteremia caused by Streptococcus canis sequence type 9 harboring the scm gene.

    Science.gov (United States)

    Taniyama, Daisuke; Abe, Yoshihiko; Sakai, Tetsuya; Kikuchi, Takahide; Takahashi, Takashi

    2017-01-01

    Streptococcus canis (Sc) is a zoonotic pathogen that is transferred mainly from companion animals to humans. One of the major virulence factors in Sc is the M-like protein encoded by the scm gene, which is involved in anti-phagocytic activities, as well as the recruitment of plasminogen to the bacterial surface in cooperation with enolase, and the consequent enhancement of bacterial transmigration and survival. This is the first reported human case of uncomplicated bacteremia following a dog bite, caused by Streptococcus canis harboring the scm gene. The similarity of the 16S rRNA from the infecting species to that of the Sc type strain, as well as the amplification of the species-specific cfg gene, encoding a co-hemolysin, was used to confirm the species identity. Furthermore, the isolate was confirmed as sequence type 9. The partial scm gene sequence harbored by the isolate was closely related to those of other two Sc strains. While this isolate did not possess the erm(A), erm(B), or mef(A), macrolide/lincosamide resistance genes, it was not susceptible to azithromycin: its susceptibility was intermediate. Even though human Sc bacteremia is rare, clinicians should be aware of this microorganism, as well as Pasteurella sp., Prevotella sp., and Capnocytophaga sp., when examining and treating patients with fever who maintain close contact with companion animals.

  2. Do Scarce Precious Metals Equate to Safe Harbor Investments? The Case of Platinum and Palladium

    Directory of Open Access Journals (Sweden)

    John Francis T. Diaz

    2016-01-01

    Full Text Available This research establishes the predictability and safe harbor properties of two scarce precious metals, namely, platinum and palladium. Utilizing their spot prices, the study concludes intermediate memory in the return structures of both precious metals, which implies the instability of platinum and palladium returns’ persistency in the long run. However, both the ARFIMA-FIGARCH and the ARFIMA-FIAPARCH models confirm long-memory properties in the volatility of the two spot prices. The leverage effects phenomenon is not also present based on the ARFIMA-APARCH and ARFIMA-FIAPARCH models, which may possibly conclude the resilience of both precious metals against increased volatility. However, further tests proved that only platinum has a symmetric volatility response to shocks with the presence of negative gamma parameter, which proves that only platinum can be considered a safe harbor investment, because negative and positive shocks have equal effects on their returns and volatilities. Comparing the four models utilized in this study, the combined ARFIMA-FIAPARCH models are the best fitting model to characterize both precious metals’ spot prices.

  3. Ecological evaluation of proposed discharge of dredged material from Oakland Harbor into ocean waters (Phase 2 of -42-foot project)

    Energy Technology Data Exchange (ETDEWEB)

    Word, J.Q.; Ward, J.A.; Strand, J.A.; Kohn, N.P.; Squires, A.L. (Battelle Marine Research Lab., Sequim, WA (USA))

    1990-09-01

    The US Army Corps of Engineers (USACE), San Francisco District, was authorized by the Water Resources Development Act of 1986 to deepen and widen the navigation channels of Inner and Outer Oakland Harbor, California, to accommodate modern deep-draft vessels. The recommended plan consists of deepening the harbor channels from the presently authorized water depth of {minus}35 ft mean lower low water (MLLW) to {minus}42 ft MLLW and supplying the harbor with adequate turning basins and berthing areas. Offshore ocean disposal of the dredged sediment is being considered, provided there is no evident of harmful ecological effects. It harmful ecological effects are not evident then the appropriate certifications from state environmental quality agencies and concurrence from the Environmental Protection Agency can be obtained to allow disposal of sediment. To help provide the scientific basis for determining whether Oakland Harbor sediments are suitable for offshore disposal, the Battelle/Marine Sciences Laboratory (MSL) collected sediment cores from 23 stations in Inner and Outer Oakland Harbor, evaluated these sediment cores geologically, performed chemical analyses for selected contaminants in sediments, conducted a series of solid phase toxicity tests with four sensitive marine invertebrates and assessed the bioaccumulation potential of sediment-associated contaminants in the tissues of Macoma Nasuta. 43 refs., 26 figs., 61 tabs.

  4. NMR-based metabolomics for the environmental assessment of Kaohsiung Harbor sediments exemplified by a marine amphipod (Hyalella azteca).

    Science.gov (United States)

    Chiu, K H; Dong, C D; Chen, C F; Tsai, M L; Ju, Y R; Chen, T M; Chen, C W

    2017-03-03

    Inflow of wastewater from upstream causes a large flux of pollutants to enter Kaohsiung Harbor in Taiwan daily. To reveal the ecological risk posed by Kaohsiung Harbor sediments, an ecological metabolomic approach was employed to investigate environmental factors pertinent to the physiological regulation of the marine amphipod Hyalella azteca. The amphipods were exposed to sediments collected from different stream inlets of the Love River (LR), Canon River (CR), Jen-Gen River (JR), and Salt River (SR). Harbor entrance 1 (E1) was selected as a reference site. After 10-day exposure, metabolomic analysis of the Hyalella azteca revealed differences between two groups: {E1, LR, CR} and {JR, SR}. The metabolic pathways identified in the two groups of amphipods were significantly different. The results demonstrated that NMR-based metabolomics can be effectively used to characterize metabolic response related to sediment from polluted areas. Copyright © 2017. Published by Elsevier Ltd.

  5. Confirmatory sediment analyses and solid and suspended particulate phase bioassays on sediment from Oakland Inner Harbor, San Francisco, California

    Energy Technology Data Exchange (ETDEWEB)

    Word, J.Q.; Ward, J.A.; Apts, C.W.; Woodruff, D.L.; Barrows, M.E.; Cullinan, V.I.; Hyland, J.L.; Campbell, J.F.

    1988-12-01

    The US Army Corps of Engineers (USACE), San Francisco District, was authorized by the US Congress to deepen the navigation channels of Inner and Outer Oakland Harbor, California. During review of the environmental impact statement required for this dredging and disposal project, a panel of national experts approved the open-water disposal of dredged sediment from selected areas within the Inner Harbor, subject to results of confirmatory solid phase bioassays. The San Francisco District of the Corps requested the Battle/Marine Sciences Laboratory (MSL) to conduct these confirmatory studies. The studies provided technical data for an evaluation of the potential environmental impact of this project. Within extremely narrow time constraints, these studies provided chemical and biological information required by ocean dumping regulations to determine suitability of the Oakland Inner Harbor and turning basin sediment for ocean disposal. 23 refs., 18 figs., 45 tabs.

  6. Cladophora (Chlorophyta) spp. harbor human bacterial pathogens in nearshore water of Lake Michigan

    Science.gov (United States)

    Ishii, S.; Yan, T.; Shively, D.A.; Byappanahalli, M.N.; Whitman, R.L.; Sadowsky, M.J.

    2006-01-01

    Cladophora glomerata, a macrophytic green alga, is commonly found in the Great Lakes, and significant accumulations occur along shorelines during the summer months. Recently, Cladophora has been shown to harbor high densities of the fecal indicator bacteria Escherichia coli and enterococci. Cladophora may also harbor human pathogens; however, until now, no studies to address this question have been performed. In the present study, we determined whether attachedCladophora, obtained from the Lake Michigan and Burns Ditch (Little Calumet River, Indiana) sides of a breakwater during the summers of 2004 and 2005, harbored the bacterial pathogens Shiga toxin-producing Escherichia coli (STEC),Salmonella, Shigella, and Campylobacter. The presence of potential pathogens and numbers of organisms were determined by using cultural methods and by using conventional PCR, most-probable-number PCR (MPN-PCR), and quantitative PCR (QPCR) performed with genus- and toxin-specific primers and probes. WhileShigella and STEC were detected in 100% and 25%, respectively, of the algal samples obtained near Burns Ditch in 2004, the same pathogens were not detected in samples collected in 2005. MPN-PCR and QPCR allowed enumeration of Salmonella in 40 to 80% of the ditch- and lakeside samples, respectively, and the densities were up to 1.6 × 103 cells per g Cladophora. Similarly, these PCR methods allowed enumeration of up to 5.4 × 102 Campylobacter cells/gCladophora in 60 to 100% of lake- and ditchside samples. The Campylobacterdensities were significantly higher (P < 0.05) in the lakeside Cladophora samples than in the ditchside Cladophora samples. DNA fingerprint analyses indicated that genotypically identical Salmonella isolates were associated with geographically and temporally distinct Cladophora samples. However, Campylobacter isolates were genetically diverse. Since animal hosts are thought to be the primary habitat for

  7. Preconstruction Engineering and Design Phase Reevaluation Report, Olcott Harbor Project, Olcott, New York. Volume 2, Supporting Documentation. Revision.

    Science.gov (United States)

    1992-09-01

    34 NCl C0h1EEEh;14: 43 IEPAI!%S 33.1t 26.1.1 4ýft1 SEE PIESSASE C4 M~IT UhtES ; .0EES~~ A*,2VE A-E NT CGfAE:C FINAL VAI.EEE SC.UTION ;e AO OF SAUET’ M1 N...TVYPICAL 5EC-T-ION LAK)EWA9P C-ELL 5ýfow N .5 C~a0’ milk OLCOTT HARBOR - INPUT FILE - CASE 2 2000 OLCOTT HARBOR - SHEET PILE CELL FOR PEDESTRIAN BRIDGE

  8. Tales of some ancient harbors in the Aegean back-arc region: Earthquakes, coastal changes, historical impacts

    Science.gov (United States)

    Stiros, Stathis; Saltogianni, Vasso

    2017-04-01

    Tectonically active terrains are characterized by seismic transient ground motions (shaking) and by permanent ground motions in the vicinity of activated faults, with both effects occasionally leaving their signature on human constructions and the landscape. Especially in coastal areas marked by small tidal ranges and normal water salinity, as is the case with most parts of the Eastern Mediterranean, even small-amplitude tectonic motions can be derived from observations on coastal constructions, mainly harbors, but also on spring chambers in nearly arid environments, sewers, etc. Such observations, if coupled with well-dated observations of destructions and repairs and of changes in the occupation style of ancient sites can permit precious information conveyed from archaeology to tectonics/seismology and vice versa. A transect with harbor remains from Rhodes to the Gulf of Corinth and then till the Ionian Islands provides some excellent examples. The military harbor of Rhodes, in an area of long term uplift, a coded report of which seems to be provided by ancient poet Pindar, was subject to seismic subsidence and destruction, but with major international support, it was repaired, till renewed uplift brought it several meters above the water. In the Corinth area, the Kenchreai harbor was abruptly submerged during a major repair of a temple, as revealed by precious stained glass panels, ready to use but abandoned in shallow water beneath ruins, while radiometric dating of the uplift in the western Lechaion harbor, constrains its excavation in swampy environment not in Roman times, but to the period of flourishing of Corinth in circa 600BC and the colonization of Italy. Farther west, the sea-level mark of the harbor of Aigeira, at Mavra Litharia (Derveni/Akrata) indicates 4m uplift since the Roman period, at least partly seismic, correlating with an exposed reef and the abandonment of the repairs of the theatre of Aigeira. Seismic land uplift explains the demise of

  9. Floating-Harbor syndrome: description of a further patient, review of the literature, and suggestion of autosomal dominant inheritance.

    Science.gov (United States)

    Lacombe, D; Patton, M A; Elleau, C; Battin, J

    1995-08-01

    The Floating-Harbor syndrome is a growth retardation syndrome with delayed bone age, speech development, and typical facial features. The face is triangular with deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips. We present an additional patient and review 16 cases from the literature. The possible phenotype in the patient's mother suggests a dominant mode of inheritance for the syndrome. The Floating Harbor syndrome is a growth deficiency syndrome characterized by proportionate short stature, characteristic face and delayed speech development. Inheritance is possibly autosomal dominant.

  10. Preparation of low water-sorption lightweight aggregates from harbor sediment added with waste glass.

    Science.gov (United States)

    Wei, Yu-Ling; Lin, Chang-Yuan; Ko, Kuan-Wei; Wang, H Paul

    2011-01-01

    A harbor sediment is successfully recycled at 1150 °C as low water-absorption lightweight aggregate via addition of waste glass powder. Sodium content in the waste glass is responsible for the formation of low-viscosity viscous phases during firing process to encapsulate the gases generated for bloating pellet samples. Water sorption capacity of the lightweight products can be considerably reduced from 5.6% to 1.5% with the addition of waste glass powder. Low water-absorption property of lightweight products is beneficial for preparing lightweight concrete because the water required for curing the cement would not be seized by lightweight aggregate filler, thus preventing the failure of long-term concrete strength. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. CFD Modelling of Local Hemodynamics in Intracranial Aneurysms Harboring Arterial Branches.

    Science.gov (United States)

    Krylov, Vladimir; Grigoryeva, Elena; Dolotova, Daria; Blagosklonova, Evgenia; Gavrilov, Andrey

    2017-01-01

    The main cause of non-traumatic subarachnoid haemorrhage is an intracranial aneurysm's rupture. The choice of treatment approach is exceptionally difficult in cases of aneurysms with additional branches on the aneurysm's dome or neck. The impact of the arterial branches on local hemodynamics is still unclear and controversial question. At the same time, up-to-date methods of image processing and mathematical modeling provide a way to investigate the hemodynamic environment of aneurysms. The paper discusses hemodynamic aspects of aneurysms harboring arterial branch through the use of patient-specific 3D models and computational fluid dynamics (CFD) methods. The analysis showed that the presence of the arterial branches has a great influence on flow streamlines and wall shear stress, particularly for side wall aneurysm.

  12. Not all floating-harbor syndrome cases are due to mutations in exon 34 of SRCAP.

    Science.gov (United States)

    Le Goff, Carine; Mahaut, Clémentine; Bottani, Armand; Doray, Berenice; Goldenberg, Alice; Moncla, Anne; Odent, Sylvie; Nitschke, Patrick; Munnich, Arnold; Faivre, Laurence; Cormier-Daire, Valérie

    2013-01-01

    Floating-Harbor syndrome (FHS) is a rare disorder characterized by short stature, delayed bone age, speech delay, and dysmorphic facial features. We report here the molecular analysis of nine cases, fulfilling the diagnostic criteria for FHS. Using exome sequencing, we identified SRCAP as the disease gene in two cases and subsequently found SRCAP truncating mutations in 6/9 cases. All mutations occurred de novo and were located in exon 34, in accordance with the recent report of Hood et al. However, the absence of SRCAP mutations in 3/9 cases supported genetic heterogeneity of FH syndrome. Importantly, no major clinical differences were observed supporting clinical homogeneity in this series of FHS patients. © 2012 Wiley Periodicals, Inc.

  13. When chromatin organisation floats astray: the Srcap gene and Floating-Harbor syndrome.

    Science.gov (United States)

    Messina, Giovanni; Atterrato, Maria Teresa; Dimitri, Patrizio

    2016-12-01

    Floating-Harbor syndrome (FHS) is a rare human disease characterised by delayed bone mineralisation and growth deficiency, often associated with mental retardation and skeletal and craniofacial abnormalities. FHS was first described at Boston's Floating Hospital 42 years ago, but the causative gene, called Srcap, was identified only recently. Truncated SRCAP protein variants have been implicated in the mechanism of FHS, but the molecular bases underlying the disease must still be elucidated and investigating the molecular defects leading to the onset of FHS remains a challenge. Here we comprehensively review recent work and provide alterative hypotheses to explain how the Srcap truncating mutations lead to the onset of FHS. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  14. Polycyclic aromatic hydrocarbons (PAHs) in starfish body and bottom sediments in Mohang Harbor (Taean), South Korea.

    Science.gov (United States)

    Kim, Chang Joon; Hong, Gi Hoon; Kim, Hye Eun; Yang, Dong Beom

    2014-07-01

    The concentrations of 27 polycyclic aromatic hydrocarbons (PAHs) were determined in bottom sediments and starfish from Mohang Harbor (MH) in Taean peninsula, South Korea. In December 2007, crude oil washed ashore from the M/V Hebei Spirit and was subsequently cleaned up within a few months of the incident. The ecological risk, bioaccumulation factor (BAF), and composition of the 27 PAHs were examined. The PAH concentrations in the bottom sediment ranged from 24 to 366 μg/kg dried weight, and the ecological risk was determined as minimal (mERL-Q starfish species. Further, PAH fingerprint analysis (nine alkyl-substituted PAHs fraction, low molecular weight (LMW)/high molecular weight (HMW), Phe/Ant, and Flu/Pyr), and principal component analysis (PCA) based on three crude oil samples from the M/V Hebei Spirit showed no remaining influence of crude oil.

  15. Physiological studies in aerobic batch cultivations of Saccharomyces cerevisiae strains harboring the MEL1 gene

    DEFF Research Database (Denmark)

    Østergaard, Simon; Roca, Christophe Francois Aime; Ronnow, B.

    2000-01-01

    Physiological studies of Saccharomyces cerevisiae strains harboring the MEL1 gene were carried out in aerobic batch cultivations on glucose-galactose mixtures and on the disaccharide melibiose, which is hydrolyzed by the enzyme melibiase (Mel1, EC 3.2.1.22) into a glucose and a galactose moiety....... The strains examined (T200, T256, M24, and TH1) were all derived from the bakers' and distillers' strain of S. cerevisiae, DGI 342. All the strains showed a significant higher ethanol yield when growing on glucose, and half the biomass yield, compared with growth on galactose. The maximum specific uptake...... strains. Growth on the glucose-galactose mixtures showed a reduction of glucose control successfully obtained in the M24 strain and the TH1 strain. (C) 2000 John Wiley & Sons, Inc....

  16. Gastric schwannoma with adjacent external progression harbored aberrant NF2 gene.

    Science.gov (United States)

    Ogasawara, Naotaka; Sasaki, Makoto; Ishiguro, Hideyuki; Itoh, Yukimi; Nojiri, Syunsuke; Kubota, Eiji; Wada, Tsuneya; Kataoka, Hiromi; Kuwabara, Yoshiyuki; Joh, Takashi

    2009-07-01

    Gastric schwannomas are rare benign mesenchymal tumors. We describe a schwannoma of gastric origin with adjacent external progression. Sections showed a spindle cell tumor arranged in interlaced bundles and fascicles that was S-100 and CD34 positive but c-KIT protein negative. Histology and immunohistochemistry revealed the typical appearance of a gastric schwannoma. Genetic evaluation revealed that the tumor harbored a point mutation in exon 6 of the tumor suppressor neurofibromatosis 2 (NF2) gene, which resulted in an amino acid substitution of NF2 protein, and no mutation in exon 4b of the NF1 gene. In conclusion, we identified a rare mutation of the NF2 gene in gastric schwannoma. A diagnosis can only be definitive when based on histological and immunohistochemical findings. Digestive tract schwannomas are rare mesenchymal tumors that are differentiated from gastrointestinal stromal tumors by the absence of KIT protein. Follow up suggested that complete resection is an effective long-term treatment strategy.

  17. Los Angeles and Long Beach Harbors Model Enhancement Program. Tidal Circulation Prototype Data Collection Effort. Volume 3. Appendix J

    Science.gov (United States)

    1989-12-01

    5 Z7 p < : r7 scW-131 3 .0 15:__ o?± c 4 /.-C ;.v gIR SAIsIi’ sc73S~ 70160 13󈧖, v, SAt-4CR L R_ __ _ is;.734 1/o ho ’I 0 .. SC ’ S 111CLR 15...SUAImSY __X ’’"L I kk. aCf L _ 2’f 15’, o al,_ _4T - SPdt THCK Sad I~~~j.TP EA NE TYPE BEGAN ENDEDO .. at PAA AA . _ 14t --e ’Cc.. ON. IAvelle ve

  18. Evaluation method for the potential functionome harbored in the genome and metagenome

    Science.gov (United States)

    2012-01-01

    Background One of the main goals of genomic analysis is to elucidate the comprehensive functions (functionome) in individual organisms or a whole community in various environments. However, a standard evaluation method for discerning the functional potentials harbored within the genome or metagenome has not yet been established. We have developed a new evaluation method for the potential functionome, based on the completion ratio of Kyoto Encyclopedia of Genes and Genomes (KEGG) functional modules. Results Distribution of the completion ratio of the KEGG functional modules in 768 prokaryotic species varied greatly with the kind of module, and all modules primarily fell into 4 patterns (universal, restricted, diversified and non-prokaryotic modules), indicating the universal and unique nature of each module, and also the versatility of the KEGG Orthology (KO) identifiers mapped to each one. The module completion ratio in 8 phenotypically different bacilli revealed that some modules were shared only in phenotypically similar species. Metagenomes of human gut microbiomes from 13 healthy individuals previously determined by the Sanger method were analyzed based on the module completion ratio. Results led to new discoveries in the nutritional preferences of gut microbes, believed to be one of the mutualistic representations of gut microbiomes to avoid nutritional competition with the host. Conclusions The method developed in this study could characterize the functionome harbored in genomes and metagenomes. As this method also provided taxonomical information from KEGG modules as well as the gene hosts constructing the modules, interpretation of completion profiles was simplified and we could identify the complementarity between biochemical functions in human hosts and the nutritional preferences in human gut microbiomes. Thus, our method has the potential to be a powerful tool for comparative functional analysis in genomics and metagenomics, able to target unknown

  19. Oral keratinocytes support non-replicative infection and transfer of harbored HIV-1 to permissive cells

    Directory of Open Access Journals (Sweden)

    Giacaman Rodrigo A

    2008-07-01

    Full Text Available Abstract Background Oral keratinocytes on the mucosal surface are frequently exposed to HIV-1 through contact with infected sexual partners or nursing mothers. To determine the plausibility that oral keratinocytes are primary targets of HIV-1, we tested the hypothesis that HIV-1 infects oral keratinocytes in a restricted manner. Results To study the fate of HIV-1, immortalized oral keratinocytes (OKF6/TERT-2; TERT-2 cells were characterized for the fate of HIV-specific RNA and DNA. At 6 h post inoculation with X4 or R5-tropic HIV-1, HIV-1gag RNA was detected maximally within TERT-2 cells. Reverse transcriptase activity in TERT-2 cells was confirmed by VSV-G-mediated infection with HIV-NL4-3Δenv-EGFP. AZT inhibited EGFP expression in a dose-dependent manner, suggesting that viral replication can be supported if receptors are bypassed. Within 3 h post inoculation, integrated HIV-1 DNA was detected in TERT-2 cell nuclei and persisted after subculture. Multiply spliced and unspliced HIV-1 mRNAs were not detectable up to 72 h post inoculation, suggesting that HIV replication may abort and that infection is non-productive. Within 48 h post inoculation, however, virus harbored by CD4 negative TERT-2 cells trans infected co-cultured peripheral blood mononuclear cells (PBMCs or MOLT4 cells (CD4+ CCR5+ by direct cell-to-cell transfer or by releasing low levels of infectious virions. Primary tonsil epithelial cells also trans infected HIV-1 to permissive cells in a donor-specific manner. Conclusion Oral keratinocytes appear, therefore, to support stable non-replicative integration, while harboring and transmitting infectious X4- or R5-tropic HIV-1 to permissive cells for up to 48 h.

  20. Haul-out behavior of harbor seals (Phoca vitulina in Hood Canal, Washington.

    Directory of Open Access Journals (Sweden)

    Josh M London

    Full Text Available The goal of this study was to model haul-out behavior of harbor seals (Phoca vitulina in the Hood Canal region of Washington State with respect to changes in physiological, environmental, and temporal covariates. Previous research has provided a solid understanding of seal haul-out behavior. Here, we expand on that work using a generalized linear mixed model (GLMM with temporal autocorrelation and a large dataset. Our dataset included behavioral haul-out records from archival and VHF radio tag deployments on 25 individual seals representing 61,430 seal hours. A novel application for increased computational efficiency allowed us to examine this large dataset with a GLMM that appropriately accounts for temporal autocorellation. We found significant relationships with the covariates hour of day, day of year, minutes from high tide and year. Additionally, there was a significant effect of the interaction term hour of day : day of year. This interaction term demonstrated that seals are more likely to haul out during nighttime hours in August and September, but then switch to predominantly daylight haul-out patterns in October and November. We attribute this change in behavior to an effect of human disturbance levels. This study also examined a unique ecological event to determine the role of increased killer whale (Orcinus orca predation on haul-out behavior. In 2003 and 2005 these harbor seals were exposed to unprecedented levels of killer whale predation and results show an overall increase in haul-out probability after exposure to killer whales. The outcome of this study will be integral to understanding any changes in population abundance as a result of increased killer whale predation.

  1. Impact of climate changes on the Santos Harbor, São Paulo State (Brazil

    Directory of Open Access Journals (Sweden)

    Paolo Alfredini

    2013-12-01

    Full Text Available Santos Harbor Area (SHA in Sao Paulo Coastline (Brazil is the most important marine cargo transfer terminal in the Southern Hemisphere. A long term relative tidal level variability assessment shows a consistent response to relative sea level rise. A wave data base Wave Watch III was compared with a long term wave data-base generated by the ERA40-ECMWF (2003, both local validated. The current bed level of SHA Outer Channel is -15.00 m (Chart Datum or, in abbreviation, CD, maintained by dredging. According to the cargo throughput forecast, in 2025, the Access Channel will have to be deepened to level of -17.00 m. The feasibility of that choice is discussed from a technical, economical and conceptual navigation point of view in that context. A data set found from a scale model of the whole area of Santos Bay, Estuary and nearby beaches, showed the impact of maritime climate changes upon the coastal area. In the previous researches developed by the authors, it was demonstrated that the wave climate, the tides and tidal currents affect harbor and coastal structures maintenance, beaches stability, tidal inlet, sediment transport, saline intrusion and wetlands. Considering the increasing of the sea hazards and the high values of the infrastructures in that coastline, it is necessary to mitigate the risks. Hence, based on the results obtained by the authors, are highlighted guidelines strategies suggested for Access Channels dimensions, wharves free-board, jetties dimensions, dredging rates, rigid and flexible littoral defenses and land protection against flooding (including wetlands.

  2. Baseline survey for rare plant species and native plant communities within the Kamehameha Schools 'Lupea Safe Harbor Planning Project Area, North Kona District, Island of Hawai'i

    Science.gov (United States)

    Jacobi, James; F. R. Warshauer, frwvolcano@hotmail.com; Jonathan Price, jpprice@hawaii.edu

    2010-01-01

    Kamehameha Schools, in conjunction with several federal, state, and private organizations, has proposed to conduct conservation management on approximately 5,340 ha (~13,200 acres) of land they own in the vicinity of Kīpukalupea in the North Kona District on the island of Hawai'i. The goal of this program is to restore and enhance the habitat to benefit native plant and animal populations that are currently, or were formerly, found in this site. The initial phase of this project has been focused on various activities including conducting baseline surveys for bird and plant species so Kamehameha Schools could develop a Safe Harbor Agreement (SHA) for the proposed project lands relative to the habitat management and species reintroduction efforts they would like to conduct in the Lupea Project area. This report summarizes methods that were used to collect field data on plant species and communities within the project area, and the results of that initial survey. The information was used to calculate baseline values for all listed threatened or endangered plant species found, or expected to be found, within the project area, and to design a monitoring program to assess changes in plant communities and rare plant species relative to management activities over the duration of the SHA.

  3. Draft Genome Sequences of Two Isolates of the Roseobacter Group, Sulfitobacter sp. Strains 3SOLIMAR09 and 1FIGIMAR09, from Harbors of Mallorca Island (Mediterranean Sea).

    Science.gov (United States)

    Mas-Lladó, Maria; Piña-Villalonga, Joana Maria; Brunet-Galmés, Isabel; Nogales, Balbina; Bosch, Rafael

    2014-05-22

    We present the draft genome sequences of two isolates of the Roseobacter lineage, 3SOLIMAR09 and 1FIGIMAR09, which were obtained from harbors of Mallorca Island, Spain, and are affiliated with the Sulfitobacter genus. Both isolates harbor the complete gene set for protocatechuate catabolism and incomplete pathways for several additional monoaromatic compounds. Copyright © 2014 Mas-Lladó et al.

  4. Influence of the Pearl River estuary and vertical mixing in Victoria Harbor on water quality in relation to eutrophication impacts in Hong Kong waters.

    Science.gov (United States)

    Yin, Kedong; Harrison, Paul J

    2007-06-01

    This study presents water quality parameters such as nutrients, phytoplankton biomass and dissolved oxygen based on 11 years of water quality data in Victoria Harbor and examined how the Pearl River estuary discharge in summer and year round sewage discharge influenced these parameters. Nutrients in Victoria Harbor were strongly influenced by both the Pearl River and sewage effluent, as indicated by the high NO(3) inputs from the Pearl River in summer and higher NH(4) and PO(4) in Victoria Harbor than both its sides. N:P ratios were low in the dry season, but increased to >16:1 in the wet season, suggesting that P is potentially the most limiting nutrient in this area during the critical period in the summer. Although there were generally high nutrients, the phytoplankton biomass was not as high as one would expect in Victoria Harbor. In fact, there were high concentrations of chl near the bottom well below the photic zone. Salinity near the bottom was lower in Victoria Harbor than at the two entrances to Victoria Harbor, suggesting strong vertical mixing within Victoria Harbor. Therefore, strong vertical mixing and horizontal advection appear to play an important role in significantly reducing eutrophication impacts in Victoria Harbor. Consequently, dissolved oxygen near the bottom was low in summer, but only occasionally dipped to 2 mgL(-1) despite the high organic loading from sewage effluent.

  5. Hearing thresholds of a harbor porpoise (Phocoena phocoena) for sweeps (1-2 kHz and 6-7 kHz bands) mimicking naval sonar signals

    NARCIS (Netherlands)

    Kastelein, R.A.; Hoek, L.; Jong, C.A.F. de

    2011-01-01

    The distance at which active naval sonar signals can be heard by harbor porpoises depends, among other factors, on the hearing thresholds of the species for those signals. Therefore the hearing sensitivity of a harbor porpoise was determined for 1 s up-sweep and down-sweep signals, mimicking

  6. 33 CFR 334.610 - Key West Harbor, at U.S. Naval Base, Key West, Fla.; naval restricted areas and danger zone.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Key West Harbor, at U.S. Naval Base, Key West, Fla.; naval restricted areas and danger zone. 334.610 Section 334.610 Navigation and... RESTRICTED AREA REGULATIONS § 334.610 Key West Harbor, at U.S. Naval Base, Key West, Fla.; naval restricted...

  7. Seroprevalence of Antibodies against Seal Influenza A(H10N7) Virus in Harbor Seals and Gray Seals from the Netherlands

    NARCIS (Netherlands)

    R. Bodewes (Rogier); A.R. García (Ana Rubio); S.M. Brasseur (Sophie M.); G.J.S. Conteras (Guillermo J. Sanchez); M.W.G. van de Bildt (Marco); M.P.G. Koopmans D.V.M. (Marion); A.D.M.E. Osterhaus (Albert); T. Kuiken (Thijs)

    2015-01-01

    textabstractIn the spring and summer 2014, an outbreak of seal influenza A(H10N7) virus infection occurred among harbor seals (Phoca vitulina) off the coasts of Sweden and Denmark. This virus subsequently spread to harbor seals off the coasts of Germany and the Netherlands. While thousands of seals

  8. Seroprevalence of Antibodies against Seal Influenza A(H10N7) Virus in Harbor Seals and Gray Seals from the Netherlands

    NARCIS (Netherlands)

    Bodewes, Rogier; Garcia, Ana Rubio; Brasseur, Sophie M.; Conteras, Guillermo J.S.; De Bildt, Van Marco W.G.; Koopmans, Marion P.G.; Osterhaus, Albert D.M.E.; Kuiken, Thijs

    2015-01-01

    In the spring and summer 2014, an outbreak of seal influenza A(H10N7) virus infection occurred among harbor seals (Phoca vitulina) off the coasts of Sweden and Denmark. This virus subsequently spread to harbor seals off the coasts of Germany and the Netherlands. While thousands of seals were

  9. Seroprevalence of Antibodies against Seal Influenza A(H10N7) Virus in Harbor Seals and Gray Seals from the Netherlands

    NARCIS (Netherlands)

    Bodewes, Rogier|info:eu-repo/dai/nl/33230583X; Rubio García, Ana; Brasseur, Sophie M; Sanchez Conteras, Guillermo J; van de Bildt, Marco W G; Koopmans, Marion P G; Osterhaus, Albert D M E|info:eu-repo/dai/nl/074960172; Kuiken, Thijs

    2015-01-01

    In the spring and summer 2014, an outbreak of seal influenza A(H10N7) virus infection occurred among harbor seals (Phoca vitulina) off the coasts of Sweden and Denmark. This virus subsequently spread to harbor seals off the coasts of Germany and the Netherlands. While thousands of seals were

  10. The influenze of signal parameters on the sound source localization ability of a harbor popoise (Phocoena phocoena)

    NARCIS (Netherlands)

    Kastelein, R.A.; Haan, de D.; Verboom, W.C.

    2007-01-01

    It is unclear how well harbor porpoises can locate sound sources, and thus can locate acoustic alarms on gillnets. Therefore the ability of a porpoise to determine the location of a sound source was determined. The animal was trained to indicate the active one of 16 transducers in a 16-m-diam circle

  11. The influence of signal parameters on the sound source localization ability of a harbor porpoise (Phocoena phocoena)

    NARCIS (Netherlands)

    Kastelein, R.A.; Haan, D.de; Verboom, W.C.

    2007-01-01

    It is unclear how well harbor porpoises can locate sound sources, and thus can locate acoustic alarms on gillnets. Therefore the ability of a porpoise to determine the location of a sound source was determined. The animal was trained to indicate the active one of 16 transducers in a 16-m -diam

  12. 33 CFR 334.530 - Canaveral Harbor adjacent to the Navy pier at Port Canaveral, Fla.; restricted area.

    Science.gov (United States)

    2010-07-01

    ... Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA...) The area. The waters of Canaveral Harbor within a line circumscribing the water approaches to the Navy... rotating, day or night, when displayed from any of the three berths along the wharf. (3) Lighted signs...

  13. Outcome of allogeneic hematopoietic stem cell transplantation in adult patients with acute myeloid leukemia harboring trisomy 8.

    Science.gov (United States)

    Konuma, Takaaki; Kondo, Tadakazu; Yamashita, Takuya; Uchida, Naoyuki; Fukuda, Takahiro; Ozawa, Yukiyasu; Ohashi, Kazuteru; Ogawa, Hiroyasu; Kato, Chiaki; Takahashi, Satoshi; Kanamori, Heiwa; Eto, Tetsuya; Nakaseko, Chiaki; Kohno, Akio; Ichinohe, Tatsuo; Atsuta, Yoshiko; Takami, Akiyoshi; Yano, Shingo

    2017-03-01

    Trisomy 8 (+8) is one of the most common cytogenetic abnormalities in adult patients with acute myeloid leukemia (AML). However, the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) in adult patients with AML harboring +8 remains unclear. To evaluate, the outcome and prognostic factors in patients with AML harboring +8 as the only chromosomal abnormality or in association with other abnormalities, we retrospectively analyzed the Japanese registration data of 631 adult patients with AML harboring +8 treated with allogeneic HSCT between 1990 and 2013. In total, 388 (61%) patients were not in remission at the time of HSCT. With a median follow-up of 38.5 months, the probability of overall survival and the cumulative incidence of relapse at 3 years were 40 and 34%, respectively. In the multivariate analysis, two or more additional cytogenetic abnormalities and not being in remission at the time of HSCT were significantly associated with a higher overall mortality and relapse. Nevertheless, no significant impact on the outcome was observed in cases with one cytogenetic abnormality in addition to +8. Although more than 60% of the patients received HSCT when not in remission, allogeneic HSCT offered a curative option for adult patients with AML harboring +8.

  14. Molecular biology of Homo sapiens: Abstracts of papers presented at the 51st Cold Spring Harbor symposium on quantitative biology

    Energy Technology Data Exchange (ETDEWEB)

    Watson, J.D.; Siniscalco, M.

    1986-01-01

    This volume contains abstracts of papers presented at the 51st Cold Springs Harbor Symposium on Quantitative Biology. The topic for this meeting was the ''Molecular Biology of Homo sapiens.'' Sessions were entitled Human Gene Map, Human Cancer Genes, Genetic Diagnosis, Human Evolution, Drugs Made Off Human Genes, Receptors, and Gene Therapy. (DT)

  15. Effects of deposition of heavy-metal-polluted harbor mud on microbial diversity and metal resistance in sandy marine sediments

    DEFF Research Database (Denmark)

    Toes, Ann-Charlotte M; Finke, Niko; Kuenen, J Gijs

    2008-01-01

    Deposition of dredged harbor sediments in relatively undisturbed ecosystems is often considered a viable option for confinement of pollutants and possible natural attenuation. This study investigated the effects of deposition of heavy-metal-polluted sludge on the microbial diversity of sandy...

  16. 76 FR 70479 - Draft Environmental Assessment and Safe Harbor Agreement for the Houston Toad Within Nine Texas...

    Science.gov (United States)

    2011-11-14

    .... Box 1306, Albuquerque, New Mexico 87103 (505) 248-6651). SUPPLEMENTARY INFORMATION: Under a Safe Harbor Agreement, participating property owners voluntarily undertake management activities to enhance...) a detailed account of conservation activities to be undertaken on the portion of the property to be...

  17. Activating health goals reduces (increases) hedonic evaluation of food brands for people who harbor highly positive (negative) affect toward them.

    Science.gov (United States)

    Connell, Paul M; Mayor, Lauren F

    2013-06-01

    Associations of pleasure and fun with junk foods have the potential to create considerable challenges for efforts to improve diets. The aim of this research was to determine whether activating health goals had the potential to exploit mixed motivations (i.e., health and pleasure) that people have related to food, and subsequently strip junk foods of the expected pleasure derived from them. In study 1, 98 participants evaluated a soft drink brand after being primed (not primed) for health. In study 2, 93 participants evaluated a presweetened breakfast cereal brand after being primed (not primed) for health. In both studies, participants who harbored highly positive feelings for the food brands devalued their hedonic judgments of them when they were primed for health. However, in an unexpected result, participants in both studies who harbored highly negative feelings for the food brands revalued their hedonic judgments of them (i.e., increased the favorability) when they were primed for health. Thus, increasing health salience is only effective in decreasing expected pleasure derived from junk foods for people who harbor positive affect toward junk food brands, and is likely counterproductive for people who harbor negative affect toward junk food brands. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Stage 2 Report for Reformulation Phase I General Design Memorandum, Cleveland Harbor, Ohio. Volume II. Appendices. Revision.

    Science.gov (United States)

    1983-02-01

    conditions inside the Lakefront Harbor with the spur breakwaters removed. 4. Ray then presented a slide show illustrating the evolution of the pro- posed...Asehelminthes Class Nematoda Alaimus sp. Dorylaimus sp. Mesodorylaimus sp. Phylum Annelida Class Polychaeta Manayunkia speciosa Class Oligochaeta. Aulodrilus

  19. 33 CFR 334.1420 - Pacific Ocean off Orote Point, Apra Harbor, Island of Guam, Marianas Islands; small arms firing...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pacific Ocean off Orote Point, Apra Harbor, Island of Guam, Marianas Islands; small arms firing range. 334.1420 Section 334.1420..., Marianas Islands; small arms firing range. (a) The danger zone. The waters within an area delineated by a...

  20. 76 FR 35742 - Superfund Site, New Bedford Harbor, New Bedford, MA: Anchorage Ground and Regulated Navigation Area

    Science.gov (United States)

    2011-06-20

    ... 165 [Docket No. USCG-2010-1119] RIN 1625-AA01; 1625-AA11 Superfund Site, New Bedford Harbor, New... Superfund Site in New Bedford, MA. The Coast Guard is also establishing a regulated navigation area (RNA... April 12, 2011, we published a notice of proposed rulemaking (NPRM) entitled ``Superfund Site, New...

  1. Demonstration of In Situ Treatment with Reactive Amendments for Contaminated Sediments in Active DoD Harbors

    Science.gov (United States)

    2017-02-10

    For contaminated sediment sites such as those near infrastructure (i.e. piers and bulkheads), in harbors, ports and shipyards that present... toxicity of contaminants in sediment. In situ treatment is an approach that involves the biological, chemical, or physical amendment of contaminated ...Bioaccumulation, Toxicity , and Sediment Chemistry The results from the treatability study demonstrated that amending the contaminated sediment

  2. The phenotype of Floating-Harbor syndrome: clinical characterization of 52 individuals with mutations in exon 34 of SRCAP

    OpenAIRE

    Nikkel, Sarah M; Dauber, Andrew; de Munnik, Sonja; Connolly, Meghan; Hood, Rebecca L; Caluseriu, Oana; Hurst, Jane; Kini, Usha; Nowaczyk, Malgorzata J M; Afenjar, Alexandra; Albrecht, Beate; Allanson, Judith E; Balestri, Paolo; Ben-Omran, Tawfeg; Brancati, Francesco

    2013-01-01

    Abstract Background Floating-Harbor syndrome (FHS) is a rare condition characterized by short stature, delays in expressive language, and a distinctive facial appearance. Recently, heterozygous truncating mutations in SRCAP were determined to be disease-causing. With the availability of a DNA based confirmatory test, we set forth to define the clinical features of this syndrome. Methods and results Clinical in...

  3. The phenotype of Floating-Harbor syndrome: Clinical characterization of 52 individuals with mutations in exon 34 of SRCAP

    NARCIS (Netherlands)

    S.M. Nikkel (Sarah); A. Dauber (Andrew); S. de Munnik (Sonja); M. Connolly (Meghan); R.L. Hood (Rebecca L); O. Caluseriu (Oana); J.A. Hurst (Jane); U. Kini (Usha); M.J.M. Nowaczyk; A. Afenjar (Alexandra); B. Albrecht; J.E. Allanson (Judith); P. Balestri (Paolo); T. Ben-Omran (Tawfeg); F. Brancati (Fred); I. Cordeiro (Isabel); B.S. Da Cunha (Bruna Santos); P.F. Delaney (Peter); A. Destrée (Anne); D.R. Fitzpatrick (David); F. Forzano (Francesca); N. Ghali (Neeti); G. Gillies (Greta); J. Harwood; Y. Hendriks; D. Héron (Delphine); A. Hoischen (Alex); E.M. Honey (Engela Magdalena); E.H. Hoefsloot (Lies); J. Ibrahim (Jennifer); C. Jacob (Claire); S.G. Kant (Sarina); C.A. Kim (Chong); E.P. Kirk (Edwin P); N.V.A.M. Knoers (Nine); D. Lacombe (Denis); C. van der Lee (Christiaan); I.F.M. Lo (Ivan F M); L.S. Lucas (Luiza S); F. Mari (Francesca); V. Mericq (Veronica); J.S. Moilanen (Jukka S); S.T. Møller (Sanne Traasdahl); S. Moortgat (Stephanie); D.T. Pilz (Daniela); K. Pope (Kate); S. Price (Susan); A. Renieri (Alessandra); J. Sá (Joaquim); J. Schoots (Jeroen); E.L. Silveira (Elizabeth L); M.E.H. Simon (Marleen); A. Slavotinek (Anne); I.K. Temple; I. van der Burgt (Ineke); B.B.A. de Vries (Bert); J.D. Weisfeld-Adams (James D); M.L. Whiteford (Margo L); D. Wierczorek (Dagmar); J.M. Wit (Jan); C.F.O. Yee (Connie Fung On); P. Beaulieu (Patrick); S.M. White (Sue M); B. Bulman; E. Bongers (Ernie); H. Brunner (Han); M. Feingold (Murray); K.M. Boycott (Kym)

    2013-01-01

    textabstractBackground: Floating-Harbor syndrome (FHS) is a rare condition characterized by short stature, delays in expressive language, and a distinctive facial appearance. Recently, heterozygous truncating mutations in SRCAP were determined to be disease-causing. With the availability of a DNA

  4. Behavioral avoidance threshold level of a harbor porpoise (Phocoena phocoena) for a continuous 50 kHz pure tone (L)

    NARCIS (Netherlands)

    Kastelein, R.A.; Verboom, W.C.; Jennings, N.; Haan, D. de

    2008-01-01

    The use of ultrasonic sounds in alarms for gillnets may be advantageous, but the deterring effects of ultrasound on porpoises are not well understood. Therefore a harbor porpoise in a large floating pen was subjected to a continuous 50 kHz pure tone with a source level of 122 +/- 3dB (re 1uPa, rms).

  5. Floating-Harbor Syndrome: report on a case in a mother and daughter, further evidence of autosomal dominant inheritance.

    Science.gov (United States)

    Arpin, Stéphanie; Afenjar, Alexandra; Dubern, Béatrice; Toutain, Annick; Cabrol, Sylvie; Héron, Delphine

    2012-01-01

    Floating-Harbor Syndrome is a growth retardation syndrome with delayed bone age, typical facial features, and retarded speech development of unknown etiology. Very few familial cases have been reported. We report on the fourth case in a mother and daughter, suggesting autosomal dominant inheritance.

  6. Behavioral avoidance threshold level of a harbor porpoise (Phocoena phocoena) for a continuous 50 kHz pure tone (L)

    NARCIS (Netherlands)

    Kastelein, R.A.; Verboom, W.C.; Jennings, N.; Haan, de D.

    2008-01-01

    The use of ultrasonic sounds in alarms for gillnets may be advantageous, but the deterring effects of ultrasound on porpoises are not well understood. Therefore a harbor porpoise in a large floating pen was subjected to a continuous 50 kHz pure tone with a source level of 122±3 dB (re 1 ¿Pa, rms).

  7. In vitro activities of 15 oral beta-lactams against Klebsiella pneumoniae harboring new extended-spectrum beta-lactamases.

    Science.gov (United States)

    Kitzis, M D; Liassine, N; Ferré, B; Gutmann, L; Acar, J F; Goldstein, F

    1990-01-01

    The activities of 15 oral beta-lactams against Klebsiella pneumoniae harboring new extended-spectrum beta-lactamases were studied. All compounds were affected by these enzymes, especially by the SHV derivatives. Except for ceftibuten, the compounds with the greatest intrinsic activity were more affected by the presence of these enzymes than were older compounds with moderate intrinsic activity. PMID:2285291

  8. Onondaga Lake Inner Harbor Dredging Design Project, Syracuse, New York: Finding of No Significant Impact and Environmental Assessment

    Science.gov (United States)

    1996-11-01

    colonial species have become ubiquitous including: Oscillatoria limnetica, Svnechococcus elongates. Gomphosphaeria lacustris. Anabaeba flos-aquae. and... photosynthesis would increase over time as water depths decreased due to shoaling and associated sedimentation. 4.3.3.2 Inner Harbor Dredging Plan...decreases in phytoplankton primary production and photosynthesis . Discharge of dredged material into the CDF site, which is presently dry, would

  9. 75 FR 3488 - Acadia National Park; Bar Harbor, ME; Acadia National Park Advisory Commission; Notice of Meeting

    Science.gov (United States)

    2010-01-21

    ... National Park Service Acadia National Park; Bar Harbor, ME; Acadia National Park Advisory Commission.... 92-463, 86 Stat. 770, 5 U.S.C. App. 1, Sec. 10), that the Acadia National Park Advisory Commission... concerning this meeting may be obtained from the Superintendent, Acadia National Park, P.O. Box 177, Bar...

  10. 33 CFR 110.6 - Portland Harbor, Portland, Maine (between Little Diamond Island and Great Diamond Island).

    Science.gov (United States)

    2010-07-01

    ... (between Little Diamond Island and Great Diamond Island). 110.6 Section 110.6 Navigation and Navigable... Areas § 110.6 Portland Harbor, Portland, Maine (between Little Diamond Island and Great Diamond Island). Beginning at the southeasterly corner of the wharf, at the most southerly point of Great Diamond Island at...

  11. Risk assessment of bioaccumulation in the food webs of two marine AMOEBE species: common tern and harbor seal

    NARCIS (Netherlands)

    Jongbloed RH; Mensink BJWG; Vethaak AD; Luttik R; Rijksinstituut voor Kust en Zee; ACT; RIKZ

    1995-01-01

    A model has been developed for calculating Maximum Permissible Concentrations (MPCs) in water for chemicals accumulating in food webs of sea birds and mammals. Calculations are carried out for two marine AMOEBE species: common tern (Sterna hirundo) and harbor seal (Phoca vitulina), and five

  12. Complete genome sequence of phocine distemper virus isolated from a harbor seal (Phoca vitulina) during the 1988 North Sea epidemic

    NARCIS (Netherlands)

    R. de Vries (René); R.J. Verbugh (Joyce); M.W.G. van de Bildt (Marco); A.D.M.E. Osterhaus (Albert); R.L. de Swart (Rik)

    2013-01-01

    textabstractPhocine distemper virus (PDV) was identified as the cause of a large morbillivirus outbreak among harbor seals in the North Sea in 1988. PDV is a member of the family Paramyxoviridae, genus Morbillivirus. Until now, no full-genome sequence of PDV has been available.

  13. Brain Meta-Transcriptomics from Harbor Seals to Infer the Role of the Microbiome and Virome in a Stranding Event.

    Directory of Open Access Journals (Sweden)

    Stephanie M Rosales

    Full Text Available Marine diseases are becoming more frequent, and tools for identifying pathogens and disease reservoirs are needed to help prevent and mitigate epizootics. Meta-transcriptomics provides insights into disease etiology by cataloguing and comparing sequences from suspected pathogens. This method is a powerful approach to simultaneously evaluate both the viral and bacterial communities, but few studies have applied this technique in marine systems. In 2009 seven harbor seals, Phoca vitulina, stranded along the California coast from a similar brain disease of unknown cause of death (UCD. We evaluated the differences between the virome and microbiome of UCDs and harbor seals with known causes of death. Here we determined that UCD stranded animals had no viruses in their brain tissue. However, in the bacterial community, we identified Burkholderia and Coxiella burnetii as important pathogens associated with this stranding event. Burkholderia were 100% prevalent and ~2.8 log2 fold more abundant in the UCD animals. Further, while C. burnetii was found in only 35.7% of all samples, it was highly abundant (~94% of the total microbial community in a single individual. In this harbor seal, C. burnetii showed high transcription rates of invading and translation genes, implicating it in the pathogenesis of this animal. Based on these data we propose that Burkholderia taxa and C. burnetii are potentially important opportunistic neurotropic pathogens in UCD stranded harbor seals.

  14. Caffeine in an Urbanized Estuary: Past and Present Influence of Wastewater Effluents in Boston Harbor, MA, USA

    Science.gov (United States)

    Caffeine has been identified by previous research as a potential tracer of sanitary wastewater. To further assess the utility of caffeine as a tracer of wastewater sources, samples from 25 sites throughout Boston Harbor were collected and analyzed for caffeine by LC-MS/MS. Caff...

  15. 77 FR 60319 - Harbor Porpoise Take Reduction Plan; Coastal Gulf of Maine Closure Area Established With a...

    Science.gov (United States)

    2012-10-03

    ... Reduction Plan; Coastal Gulf of Maine Closure Area Established With a Temporary Shift of Its Effective Date...), Commerce. ACTION: Establishment of the Coastal Gulf of Maine Closure Area; temporary shift of its effective... establishment of the Coastal Gulf of Maine Closure Area under the Harbor Porpoise Take Reduction Plan (Plan...

  16. Retail ready-to-eat food as a potential vehicle for Staphylococcus spp. harboring antibiotic resistance genes.

    Science.gov (United States)

    Chajęcka-Wierzchowska, Wioleta; Zadernowska, Anna; Nalepa, Beata; Sierpińska, Magda; Laniewska-Trokenheim, Lucja

    2014-06-01

    Ready-to-eat (RTE) food, which does not need thermal processing before consumption, could be a vehicle for the spread of antibiotic-resistant microorganisms. As part of general microbiological safety checks, staphylococci are routinely enumerated in these kinds of foods. However, the presence of antibiotic-resistant staphylococci in RTE food is not routinely investigated, and data are only available from a small number of studies. The present study evaluated the pheno- and genotypical antimicrobial resistance profile of Staphylococcus spp. isolated from 858 RTE foods (cheeses, cured meats, sausages, smoked fishes, salads). Of 113 strains isolated, S. aureus was the most prevalent species, followed by S. xylosus, S. saprophyticus, and S. epidermidis. More than half (54.9%) of the isolates were resistant to at least one class of tested antibiotic; of these, 35.4% of the strains were classified as multidrug resistant. Most of the isolates were resistant to cefoxitin (49.6%), followed by clindamycin (39.3%), tigecycline (27.4%), quinupristin-dalfopristin (22.2%), rifampin (20.5%), tetracycline (17.9%), and erythromycin (8.5%). All methicillin-resistant staphylococci harbored the mecA gene. Among the isolates resistant to at least one antibiotic, 38 harbored tetracycline resistance determinant tet (M), 24 harbored tet (L), and 9 harbored tet (K). Of the isolates positive for tet (M) genes, 34.2% were positive for the Tn916-Tn1545-like integrase family gene. Our results indicated that retail RTE food could be considered an important route for the transmission of antibiotic-resistant bacteria harboring multiple antibiotic resistance genes.

  17. Red mangrove (Rhizophora mangle) reproduction and seedling colonization after Hurricane Charley: Comparisons of Charlotte Harbor and Tampa Bay

    Science.gov (United States)

    Proffitt, C.E.; Milbrandt, E.C.; Travis, S.E.

    2006-01-01

    Reproductive aspects of life history are known to be important in recovery following disturbance in many plant species although this has not been well studied in mangroves. Hurricane Charley devastated large areas of mangroves in Charlotte Harbor, Florida, in August 2004. We surveyed 6 forests in Charlotte Harbor (2002, 2003, and 2005) and 16 in Tampa Bay, Florida (2001, 2002, 2003, and 2005) for total numbers of reproducing trees and trees heterozygotic for albinism that produce both normal and albino propagules. Tree size (estimated height and diameter at breast height) was also recorded for sentinel heterozygotic trees. Total number of reproducing trees km-1 was used as an index of reproductive output of the population, and deviation from the 3:1 (normal:albino propagules) ratio on heterozygotic trees expected with 100% selfing was used to estimate outcrossing. Numbers of Rhizophora mangle reproducing trees km-1 of shoreline in Charlotte Harbor were reduced by an order of magnitude following Hurricane Charley, while numbers of reproducing trees in Tampa Bay were similar to those of previous years. Reduced reproduction in Charlotte Harbor was accompanied by fewer new recruits in plots on Sanibel and Captiva Islands. Numbers of new recruits after the storm also tended to be fewer in plots where canopy loss was greater. More new recruits occurred in sites that had higher densities of pre-storm Rhizophora seedlings and greater relative dominance by Rhizophora. Outcrossing of sentinel trees was 2.5 times greater in Charlotte Harbor (mean site-1 = 33.6 ?? 6.7%; with 17% of forest sites completely selfing) than in Tampa Bay (mean site-1 = 13.4 ?? 4.7%; with 40% of sites completely selfing), although the implications for seedling recruitment of this difference are not known. ?? 2006 Estuarine Research Federation.

  18. Spatially Explicit Analysis of Genome-Wide SNPs Detects Subtle Population Structure in a Mobile Marine Mammal, the Harbor Porpoise.

    Directory of Open Access Journals (Sweden)

    Ljerka Lah

    Full Text Available The population structure of the highly mobile marine mammal, the harbor porpoise (Phocoena phocoena, in the Atlantic shelf waters follows a pattern of significant isolation-by-distance. The population structure of harbor porpoises from the Baltic Sea, which is connected with the North Sea through a series of basins separated by shallow underwater ridges, however, is more complex. Here, we investigated the population differentiation of harbor porpoises in European Seas with a special focus on the Baltic Sea and adjacent waters, using a population genomics approach. We used 2872 single nucleotide polymorphisms (SNPs, derived from double digest restriction-site associated DNA sequencing (ddRAD-seq, as well as 13 microsatellite loci and mitochondrial haplotypes for the same set of individuals. Spatial principal components analysis (sPCA, and Bayesian clustering on a subset of SNPs suggest three main groupings at the level of all studied regions: the Black Sea, the North Atlantic, and the Baltic Sea. Furthermore, we observed a distinct separation of the North Sea harbor porpoises from the Baltic Sea populations, and identified splits between porpoise populations within the Baltic Sea. We observed a notable distinction between the Belt Sea and the Inner Baltic Sea sub-regions. Improved delineation of harbor porpoise population assignments for the Baltic based on genomic evidence is important for conservation management of this endangered cetacean in threatened habitats, particularly in the Baltic Sea proper. In addition, we show that SNPs outperform microsatellite markers and demonstrate the utility of RAD-tags from a relatively small, opportunistically sampled cetacean sample set for population diversity and divergence analysis.

  19. Good survival outcome of metastatic SDH-deficient gastrointestinal stromal tumors harboring SDHA mutations.

    Science.gov (United States)

    Pantaleo, Maria A; Lolli, Cristian; Nannini, Margherita; Astolfi, Annalisa; Indio, Valentina; Saponara, Maristella; Urbini, Milena; La Rovere, Stefano; Gill, Antony; Goldstein, David; Ceccarelli, Claudio; Santini, Donatella; Rossi, Giulio; Fiorentino, Michelangelo; Di Scioscio, Valerio; Fusaroli, Pietro; Mandrioli, Anna; Gatto, Lidia; Catena, Fausto; Basso, Umberto; Ercolani, Giorgio; Pinna, Antonio Daniele; Biasco, Guido

    2015-05-01

    A subset of patients with KIT/PDGFRA wild-type gastrointestinal stromal tumors show loss of function of succinate dehydrogenase, mostly due to germ-line mutations of succinate dehydrogenase subunits, with a predominance of succinate dehydrogenase subunit A. The clinical outcome of these patients seems favorable, as reported in small series in which patients were individually described. This work evaluates a retrospective survival analysis of a series of patients with metastatic KIT/PDGFRA wild-type succinate dehydrogenase-deficient gastrointestinal stromal tumors. Sixty-nine patients with metastatic gastrointestinal stromal tumors were included in the study (11 KIT/PDGFRA wild-type, of whom 6 were succinate dehydrogenase deficient, 5 were non-succinate dehydrogenase deficient, and 58 were KIT/PDGFRA mutant). All six succinate dehydrogenase-deficient patients harbored SDHA mutations. Kaplan-Meier curves and log-rank tests were used to compare the survival of patients with succinate dehydrogenase subunit A-mutant gastrointestinal stromal tumors with that of KIT/PDGFRA wild-type patients without succinate dehydrogenase deficiency and patients with KIT/PDGFRA-mutant gastrointestinal stromal tumors. Follow-up ranged from 8.5 to 200.7 months. The difference between succinate dehydrogenase subunit A-mutant gastrointestinal stromal tumors and KIT/PDGFRA-mutant or KIT/PDGFRA wild-type non-succinate dehydrogenase deficient gastrointestinal stromal tumors was significant considering different analyses (P = 0.007 and P = 0.033, respectively, from diagnosis of gastrointestinal stromal tumor for the whole study population; P = 0.005 and P = 0.018, respectively, from diagnosis of metastatic disease for the whole study population; P = 0.007 for only patients who were metastatic at diagnosis). Patients with metastatic KIT/PDGFRA wild-type succinate dehydrogenase-deficient gastrointestinal stromal tumors harboring succinate dehydrogenase subunit A mutations present an impressively

  20. High Resolution Tsunami Modeling and Assessment of Harbor Resilience; Case Study in Istanbul

    Science.gov (United States)

    Cevdet Yalciner, Ahmet; Aytore, Betul; Gokhan Guler, Hasan; Kanoglu, Utku; Duzgun, Sebnem; Zaytsev, Andrey; Arikawa, Taro; Tomita, Takashi; Ozer Sozdinler, Ceren; Necmioglu, Ocal; Meral Ozel, Nurcan

    2014-05-01

    Ports and harbors are the major vulnerable coastal structures under tsunami attack. Resilient harbors against tsunami impacts are essential for proper, efficient and successful rescue operations and reduction of the loss of life and property by tsunami disasters. There are several critical coastal structures as such in the Marmara Sea. Haydarpasa and Yenikapi ports are located in the Marmara Sea coast of Istanbul. These two ports are selected as the sites of numerical experiments to test their resilience under tsunami impact. Cargo, container and ro-ro handlings, and short/long distance passenger transfers are the common services in both ports. Haydarpasa port has two breakwaters with the length of three kilometers in total. Yenikapi port has one kilometer long breakwater. The accurate resilience analysis needs high resolution tsunami modeling and careful assessment of the site. Therefore, building data with accurate coordinates of their foot prints and elevations are obtained. The high resolution bathymetry and topography database with less than 5m grid size is developed for modeling. The metadata of the several types of structures and infrastructure of the ports and environs are processed. Different resistances for the structures/buildings/infrastructures are controlled by assigning different friction coefficients in a friction matrix. Two different tsunami conditions - high expected and moderate expected - are selected for numerical modeling. The hybrid tsunami simulation and visualization codes NAMI DANCE, STOC-CADMAS System are utilized to solve all necessary tsunami parameters and obtain the spatial and temporal distributions of flow depth, current velocity, inundation distance and maximum water level in the study domain. Finally, the computed critical values of tsunami parameters are evaluated and structural performance of the port components are discussed in regard to a better resilience. ACKNOWLEDGEMENTS: Support by EU 603839 ASTARTE Project, UDAP-Ç-12

  1. Laboratory tests for the phytoextraction of heavy metals from polluted harbor sediments using aquatic plants.

    Science.gov (United States)

    Mânzatu, Carmen; Nagy, Boldizsár; Ceccarini, Alessio; Iannelli, Renato; Giannarelli, Stefania; Majdik, Cornelia

    2015-12-30

    The aim of this study was to investigate the concentrations and pollution levels of heavy metals, organochlorine pesticides, and polycyclic aromatic hydrocarbons in marine sediments from the Leghorn Harbor (Italy) on the Mediterranean Sea. The phytoextraction capacity of three aquatic plants Salvinia natans, Vallisneria spiralis, and Cabomba aquatica was also tested in the removal of lead and copper, present in high concentration in these sediments. The average detectable concentrations of metals accumulated by the plants in the studied area were as follows: >3.328 ± 0.032 mg/kg dry weight (DW) of Pb and 2.641 ± 0.014 mg/kg DW of Cu for S. natans, >3.107 ± 0.034 g/kg DW for V. spiralis, and >2.400 ± 0.029 mg/kg DW for C. aquatica. The occurrence of pesticides was also analyzed in the sediment sample by gas chromatography coupled with mass spectrometry (GC/MS). Due to its metal and organic compound accumulation patterns, S. natans is a potential candidate in phytoextraction strategies. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome.

    Directory of Open Access Journals (Sweden)

    Mark C Wallen

    Full Text Available Site-specific recombinases (SSRs are valuable tools for genetic engineering due to their ability to manipulate DNA in a highly specific manner. Engineered zinc-finger and TAL effector recombinases, in particular, are two classes of SSRs composed of custom-designed DNA-binding domains fused to a catalytic domain derived from the resolvase/invertase family of serine recombinases. While TAL effector and zinc-finger proteins can be assembled to recognize a wide range of possible DNA sequences, recombinase catalytic specificity has been constrained by inherent base requirements present within each enzyme. In order to further expand the targeted recombinase repertoire, we used a genetic screen to isolate enhanced mutants of the Bin and Tn21 recombinases that recognize target sites outside the scope of other engineered recombinases. We determined the specific base requirements for recombination by these enzymes and demonstrate their potential for genome engineering by selecting for variants capable of specifically recombining target sites present in the human CCR5 gene and the AAVS1 safe harbor locus. Taken together, these findings demonstrate that complementing functional characterization with protein engineering is a potentially powerful approach for generating recombinases with expanded targeting capabilities.

  3. Acoustic radiation from the head of echolocating harbor porpoises (Phocoena phocoena).

    Science.gov (United States)

    Au, Whitlow W L; Kastelein, Ronald A; Benoit-Bird, Kelly J; Cranford, Ted W; McKenna, Megan F

    2006-07-01

    An experiment was conducted to investigate the sound pressure patterns on the melon of odontocetes by using four broadband hydrophones embedded in suction cups to measure echolocation signals on the surface of the forehead of two harbor porpoises (Phocoena phocoena). It has long been hypothesized that the special lipids found in the melon of odontocetes, and not in any other mammals, focus sounds produced in the nasal region that then propagate through the melon, producing a beam that is directional in both the horizontal and vertical planes. The results of our measurements supported the melon-focusing hypothesis, with the maximum click amplitude, representing the axis of the echolocation beam, located approximately 5.6-6.1 cm from the edge of the animal's upper lip along the midline of the melon. The focusing is not sharp but is sufficient to produce a transmission beam of about 16 degrees. Click amplitude dropped off rapidly at locations away from the location of site of maximum amplitude. Based on comparisons of forehead anatomy from similar sized porpoises, the beam axis coincided with a pathway extending from the phonic lips through the axis of the low-density/low sound velocity lipid core of the melon. The significant interaction between click number and hydrophone position suggests that the echolocation signals can take slightly different pathways through the melon, probably as a result of how the signals are launched by the production mechanism and the position of the acoustically reflective air sacs.

  4. Electrodialytic removal of Cu, Zn, Pb, and Cd from harbor sediment: Influence of changing experimental conditions

    DEFF Research Database (Denmark)

    Nystrøm, Gunvor Marie; Ottosen, Lisbeth M.; Villumsen, Arne

    2005-01-01

    Electrodialytic remediation (EDR) was used to remove Cu, Zn, Pb, and Cd from contaminated harbor sediment. Extraction experiments were made prior to EDR, and the metal desorption was pH dependent but not liquid-to-solid ratio (L/S) dependent. The desorption order was Cd $GRT Zn $GRT Pb $GRT Cu....... Electrodialytic experiments were made with HCl as desorbing agent in a sediment suspension, which was stirred during EDR. Effects of different current strengths and L/S ratios on the heavy metal removal were investigated on wet and air-dried sediment. The effects of drying the sediment were negligible...... was in an experiment with dry sediment (L/S 8) and a 70 mA applied current that lasted 14 days. These experimental conditions were thereafter used to remediate more strongly contaminated sediments. Regardless of the initial heavy metal concentrations in the sediments, 67-87% Cu, 79-98% Cd, 90-97% Zn, and 91-96% Pb...

  5. Occurrence and Genomic Characterization of ESBL-Producing, MCR-1-Harboring Escherichia coli in Farming Soil

    Directory of Open Access Journals (Sweden)

    Beiwen Zheng

    2017-12-01

    Full Text Available The emergence and spread of the mobile colistin resistance gene (mcr-1 has become a major global public health concern. So far, this gene has been widely detected in food animals, pets, food, and humans. However, there is little information on the contamination of mcr-1-containing bacteria in farming soils. In August 2016, a survey of ESBL-producing Escherichia coli isolated from farming soils was conducted in Shandong Province, China. We observed colistin resistance in 12 of 53 (22.6% ESBL-producing Enterobacteriaceae isolates from farming soil. Six mcr-1-positive E. coli strains originating from a livestock-intensive area were found. The isolates belonged to four different STs (ST2060, ST3014, ST6756, and ST1560 and harbored extensive additional resistance genes. An E. coli with blaNDM-1 was also detected in a soil sample from the same area. Comparative whole genome sequencing and S1-PFGE analysis indicated that mcr-1 was chromosomally encoded in four isolates and located on IncHI2 plasmids in two isolates. To our knowledge, we report the first isolation of mcr-1 in ESBL-producing E. coli from farming soils. This work highlights the importance of active surveillance of colistin-resistant organisms in soil. Moreover, investigations addressing the influence of animal manure application on the transmission of mcr-1-producing bacteria are also warranted.

  6. Use of multicriteria involvement processes to enhance transparency and stakeholder participation at Bergen Harbor, Norway.

    Science.gov (United States)

    Sparrevik, Magnus; Barton, David N; Oen, Amy M P; Sehkar, Nagothu Udaya; Linkov, Igor

    2011-07-01

    Use of participatory stakeholder engagement processes could be important to reduce the risk of potential conflicts in managing contaminated sites. Most stakeholder engagement techniques are qualitative in nature and require experienced facilitators. This study proposes a multicriteria involvement process to enhance transparency and stakeholder participation and applies it to a contaminated sediment management case study for Bergen Harbor, Norway. The suggested multicriteria involvement process builds on the quantitative principles of multicriteria decision analysis and also incorporates group interaction and learning through qualitative participatory methods. Three different advisory groups consisting of local residents, local stakeholders, and nonresident sediment experts were invited to participate in a stakeholder engagement process to provide consensual comparative advice on sediment remediation alternatives. In order for stakeholders or residents to be able to embrace a complex decision such as selection of remediation alternatives, the involvement process with lateral learning, combined with multicriteria decision analysis providing structure, robustness and transparent documentation was preferable. In addition, a multicriteria involvement process resulted in consistent ranking of remediation alternatives across residents, stakeholder, and experts, relative to individual intuitive ranking without the multicriteria involvement process. Copyright © 2011 SETAC.

  7. Postharvest Analysis of Lowland Transgenic Tomato Fruits Harboring hpRNAi-ACO1 Construct

    Directory of Open Access Journals (Sweden)

    Bita Behboodian

    2012-01-01

    Full Text Available The plant hormone, ethylene, is an important regulator which involved in regulating fruit ripening and flower senescence. In this study, RNA interference (RNAi technology was employed to silence the genes involved in ethylene biosynthetic pathway. This was achieved by blocking the expression of specific gene encoding the ACC oxidase. Initially, cDNA corresponding to ACO1 of lowland tomato cultivar (MT1, which has high identity with ACO1 of Solanum lycopersicum in GenBank, was cloned through RT-PCR. Using a partial coding region of ACO1, one hpRNAi transformation vector was constructed and expressed ectopically under the 35S promoter. Results showed that transgenic lines harboring the hpRNA-ACO1 construct had lower ethylene production and a longer shelf life of 32 days as compared to 10 days for wild-type fruits. Changes in cell wall degrading enzyme activities were also investigated in cases where the transgenic fruits exhibited reduced rates of firmness loss, which can be associated with a decrease in pectin methylesterase (PME and polygalacturonase (PG activities. However, no significant change was detected in both transgenic and wild-type fruits in terms of β-galactosidase (β-Gal activity and levels of total soluble solid, titratable acid and ascorbic acid.

  8. Biofilm-Forming ClinicalStaphylococcusIsolates Harbor Horizontal Transfer and Antibiotic Resistance Genes.

    Science.gov (United States)

    Águila-Arcos, Sandra; Álvarez-Rodríguez, Itxaso; Garaiyurrebaso, Olatz; Garbisu, Carlos; Grohmann, Elisabeth; Alkorta, Itziar

    2017-01-01

    Infections caused by staphylococci represent a medical concern, especially when related to biofilms located in implanted medical devices, such as prostheses and catheters. Unfortunately, their frequent resistance to high doses of antibiotics makes the treatment of these infections a difficult task. Moreover, biofilms represent a hot spot for horizontal gene transfer (HGT) by bacterial conjugation. In this work, 25 biofilm-forming clinical staphylococcal isolates were studied. We found that Staphylococcus epidermidis isolates showed a higher biofilm-forming capacity than Staphylococcus aureus isolates. Additionally, horizontal transfer and relaxase genes of two common staphylococcal plasmids, pSK41 and pT181, were detected in all isolates. In terms of antibiotic resistance genes, aac6-aph2a, ermC , and tetK genes, which confer resistance to gentamicin, erythromycin, and tetracycline, respectively, were the most prevalent. The horizontal transfer and antibiotic resistance genes harbored on these staphylococcal clinical strains isolated from biofilms located in implanted medical devices points to the potential risk of the development and dissemination of multiresistant bacteria.

  9. Mutations in SRCAP, encoding SNF2-related CREBBP activator protein, cause Floating-Harbor syndrome.

    Science.gov (United States)

    Hood, Rebecca L; Lines, Matthew A; Nikkel, Sarah M; Schwartzentruber, Jeremy; Beaulieu, Chandree; Nowaczyk, Małgorzata J M; Allanson, Judith; Kim, Chong Ae; Wieczorek, Dagmar; Moilanen, Jukka S; Lacombe, Didier; Gillessen-Kaesbach, Gabriele; Whiteford, Margo L; Quaio, Caio Robledo D C; Gomy, Israel; Bertola, Debora R; Albrecht, Beate; Platzer, Konrad; McGillivray, George; Zou, Ruobing; McLeod, D Ross; Chudley, Albert E; Chodirker, Bernard N; Marcadier, Janet; Majewski, Jacek; Bulman, Dennis E; White, Susan M; Boycott, Kym M

    2012-02-10

    Floating-Harbor syndrome (FHS) is a rare condition characterized by short stature, delayed osseous maturation, expressive-language deficits, and a distinctive facial appearance. Occurrence is generally sporadic, although parent-to-child transmission has been reported on occasion. Employing whole-exome sequencing, we identified heterozygous truncating mutations in SRCAP in five unrelated individuals with sporadic FHS. Sanger sequencing identified mutations in SRCAP in eight more affected persons. Mutations were de novo in all six instances in which parental DNA was available. SRCAP is an SNF2-related chromatin-remodeling factor that serves as a coactivator for CREB-binding protein (CREBBP, better known as CBP, the major cause of Rubinstein-Taybi syndrome [RTS]). Five SRCAP mutations, two of which are recurrent, were identified; all are tightly clustered within a small (111 codon) region of the final exon. These mutations are predicted to abolish three C-terminal AT-hook DNA-binding motifs while leaving the CBP-binding and ATPase domains intact. Our findings show that SRCAP mutations are the major cause of FHS and offer an explanation for the clinical overlap between FHS and RTS. Copyright © 2012 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  10. [Floating-Harbor syndrome: first case in Italy associated with growth hormone deficiency].

    Science.gov (United States)

    Femiano, P; Castaldo, V; Scarano, G

    2000-04-01

    The Floating-Harbor Syndrome (FHS) is a rare entity characterised by a clinical triad: facial dysmorphism, retarded speech development and short stature with delayed bone age. The case of a 9-year and 8/12 months old boy showing the typical features of this syndrome associated to a severe GH deficiency is reported. At diagnosis of FHS, the weight was 16 kg ( 90 degrees percentile). The evaluation of growth hormone secretion by two Insulin Tolerance Tests confirmed an insufficient GH peaks response (2.7 ng/ml and 4.6 ng/ml). He had a slight mental delay (IQ: 60) involving language skills. After 1 year of treatment with r-hGH (0.6 IU/kg/week), an increase in growth velocity (11 cm/year) in the length (123 cm), and in body weight (20.5) has been observed. This case is the 22nd report with this syndrome and the first in Italy. The association between GH deficiency and FHS, and the beneficial effects of a substitutive treatment are described.

  11. Non-Human Primates Harbor Diverse Mammalian and Avian Astroviruses Including Those Associated with Human Infections.

    Directory of Open Access Journals (Sweden)

    Erik A Karlsson

    Full Text Available Astroviruses (AstVs are positive sense, single-stranded RNA viruses transmitted to a wide range of hosts via the fecal-oral route. The number of AstV-infected animal hosts has rapidly expanded in recent years with many more likely to be discovered because of the advances in viral surveillance and next generation sequencing. Yet no study to date has identified human AstV genotypes in animals, although diverse AstV genotypes similar to animal-origin viruses have been found in children with diarrhea and in one instance of encephalitis. Here we provide important new evidence that non-human primates (NHP can harbor a wide variety of mammalian and avian AstV genotypes, including those only associated with human infection. Serological analyses confirmed that >25% of the NHP tested had antibodies to human AstVs. Further, we identified a recombinant AstV with parental relationships to known human AstVs. Phylogenetic analysis suggests AstVs in NHP are on average evolutionarily much closer to AstVs from other animals than are AstVs from bats, a frequently proposed reservoir. Our studies not only demonstrate that human astroviruses can be detected in NHP but also suggest that NHP are unique in their ability to support diverse AstV genotypes, further challenging the paradigm that astrovirus infection is species-specific.

  12. Harbor porpoise Phocoena phocoena strandings on the Dutch coast: No genetic structure, but evidence of inbreeding

    Science.gov (United States)

    van der Plas-Duivesteijn, Suzanne J.; Smit, Femmie J. L.; van Alphen, Jacques J. M.; Kraaijeveld, Ken

    2015-03-01

    Conservation management in the North Sea is often motivated by the population size of marine mammals, like harbor porpoises Phocoena phocoena. In the Dutch part of the North Sea, sighting and stranding data are used to estimate population sizes, but these data give little insight into genetic structuring of the population. In this study we investigated genetic structure among animals stranded at different locations and times of year. We also tested whether there is a link between stranding and necropsy data, and genetic diversity. We made use of both mitochondrial (mtDNA) and microsatellite DNA analysis of samples from dead stranded porpoises along the Dutch coast during 2007. mtDNA analysis showed 6 variable positions in the control region, defining 3 different haplotypes. mtDNA haplotypes were not randomly distributed along the Dutch coastline. However, microsatellite analysis showed that these mtDNA haplotypes did not represent separate groups on a nuclear level. Furthermore, microsatellite analysis revealed no genotypic differences between seasons, locations or genders. The results of this study indicate that the Dutch population is panmictic. In contrast, heterozygosity levels were low, indicating some level of inbreeding in this population. However, this was not corroborated by other indices of inbreeding. This research provided insight into genetic structuring of stranded porpoises in 2007, but data from multiple years should be included to be able to help estimate population sizes.

  13. A New Israeli Tobamovirus Isolate Infects Tomato Plants Harboring Tm-22 Resistance Genes.

    Science.gov (United States)

    Luria, Neta; Smith, Elisheva; Reingold, Victoria; Bekelman, Ilana; Lapidot, Moshe; Levin, Ilan; Elad, Nadav; Tam, Yehudit; Sela, Noa; Abu-Ras, Ahmad; Ezra, Nadav; Haberman, Ami; Yitzhak, Liron; Lachman, Oded; Dombrovsky, Aviv

    2017-01-01

    An outbreak of a new disease infecting tomatoes occurred in October-November 2014 at the Ohad village in Southern Israel. Symptomatic plants showed a mosaic pattern on leaves accompanied occasionally by narrowing of leaves and yellow spotted fruit. The disease spread mechanically and rapidly reminiscent of tobamovirus infection. Epidemiological studies showed the spread of the disease in various growing areas, in the South and towards the Southeast and Northern parts of the country within a year. Transmission electron microscope (TEM) analysis showed a single rod-like form characteristic to the Tobamovirus genus. We confirmed Koch's postulates for the disease followed by partial host range determination and revealed that tomato cultivars certified to harbor the Tm-22 resistance gene are susceptible to the new viral disease. We further characterized the viral source of the disease using a range of antisera for serological detection and analyzed various virus genera and families for cross-reactivity with the virus. In addition, next generation sequencing of total small RNA was performed on two cultivars grown in two different locations. In samples collected from commercial cultivars across Israel, we found a single virus that caused the disease. The complete genome sequence of the new Israeli tobamovirus showed high sequence identity to the Jordanian isolate of tomato brown rugose fruit virus.

  14. A New Israeli Tobamovirus Isolate Infects Tomato Plants Harboring Tm-22 Resistance Genes.

    Directory of Open Access Journals (Sweden)

    Neta Luria

    Full Text Available An outbreak of a new disease infecting tomatoes occurred in October-November 2014 at the Ohad village in Southern Israel. Symptomatic plants showed a mosaic pattern on leaves accompanied occasionally by narrowing of leaves and yellow spotted fruit. The disease spread mechanically and rapidly reminiscent of tobamovirus infection. Epidemiological studies showed the spread of the disease in various growing areas, in the South and towards the Southeast and Northern parts of the country within a year. Transmission electron microscope (TEM analysis showed a single rod-like form characteristic to the Tobamovirus genus. We confirmed Koch's postulates for the disease followed by partial host range determination and revealed that tomato cultivars certified to harbor the Tm-22 resistance gene are susceptible to the new viral disease. We further characterized the viral source of the disease using a range of antisera for serological detection and analyzed various virus genera and families for cross-reactivity with the virus. In addition, next generation sequencing of total small RNA was performed on two cultivars grown in two different locations. In samples collected from commercial cultivars across Israel, we found a single virus that caused the disease. The complete genome sequence of the new Israeli tobamovirus showed high sequence identity to the Jordanian isolate of tomato brown rugose fruit virus.

  15. Model-Based Detection of Radioactive Contraband for Harbor Defense Incorporating Compton Scattering Physics

    Energy Technology Data Exchange (ETDEWEB)

    Candy, J V; Chambers, D H; Breitfeller, E F; Guidry, B L; Verbeke, J M; Axelrod, M A; Sale, K E; Meyer, A M

    2010-03-02

    The detection of radioactive contraband is a critical problem is maintaining national security for any country. Photon emissions from threat materials challenge both detection and measurement technologies especially when concealed by various types of shielding complicating the transport physics significantly. This problem becomes especially important when ships are intercepted by U.S. Coast Guard harbor patrols searching for contraband. The development of a sequential model-based processor that captures both the underlying transport physics of gamma-ray emissions including Compton scattering and the measurement of photon energies offers a physics-based approach to attack this challenging problem. The inclusion of a basic radionuclide representation of absorbed/scattered photons at a given energy along with interarrival times is used to extract the physics information available from the noisy measurements portable radiation detection systems used to interdict contraband. It is shown that this physics representation can incorporated scattering physics leading to an 'extended' model-based structure that can be used to develop an effective sequential detection technique. The resulting model-based processor is shown to perform quite well based on data obtained from a controlled experiment.

  16. Diversity and Distribution of Sediment ureC-Harboring Microbiota in the Northern South China Sea.

    Science.gov (United States)

    Wei, X.

    2016-02-01

    Urea is an important component of marine nitrogen cycle. It's hydrolyzed by microbes for nitrogen assimilation or energy metabolism via ammonia oxidation. Urea hydrolysis also significantly influences the sediment-to-seawater flux of nitrogenous nutrients. So far, studies of marine ureolytic microorganisms mainly focused on seawater environments, yet little is known about the diversity, community structure and controlling environmental factors of ureolytic microorganisms in marine sediment environments. In the current study, we investigated the diversity, abundance, composition, activity, biogeographical distribution and controlling environmental factors of putatively ureolytic microorganisms from 12 sampling stations of the northern South China Sea, including distinct estuarine, coastal, offshore, and deep-sea habitats, using bacterial and archaea ureC genes as sequence biomarkers. Diverse archaeal and bacterial ureC gene sequences were obtained and sediment ureolytic activities were identified in all the sampling environments. Key environmental factors that may shape the community structure and spatial distribution of the ureC-harboring bacteria and archaea have been identified. Our results demonstrated that urea utilizing microorganisms may play an important role in marine nitrogen cycling in diverse sediment environments.

  17. Staphylococcal food poisoning caused by Staphylococcus argenteus harboring staphylococcal enterotoxin genes.

    Science.gov (United States)

    Wakabayashi, Yuki; Umeda, Kaoru; Yonogi, Shinya; Nakamura, Hiromi; Yamamoto, Kaori; Kumeda, Yuko; Kawatsu, Kentaro

    2018-01-16

    Staphylococcal food poisoning (SFP) is caused by staphylococcal enterotoxins (SEs) preformed in food materials. SE genes are encoded on mobile genetic elements and are widely found across Staphylococcus species including S. argenteus, although most SFP cases are caused by S. aureus. S. argenteus, recently discriminated from S. aureus as a novel species, are non-pigmented staphylococci phenotypically related to S. aureus. In 2014 and 2015, two independent food poisoning cases occurred in Osaka, Japan, in which non-pigmented staphylococci were predominantly isolated. Several enterotoxin genes (seb, seg, sei, sem, sen, seo, and selu2) were found in their genome and the production of SEB was confirmed by reverse passive agglutination tests. The non-pigmented isolates from patients, food handlers, food, and cooking utensils all produced the same pulsed-field gel electrophoresis pattern. These non-pigmented isolates were coagulase-positive and biochemically identical to S. aureus. We performed further genetic analysis using nucA sequencing and multi-locus sequence typing, and identified these isolates as S. argenteus. We also found that seb was encoded on the Staphylococcus aureus pathogenicity island, while seg, sei, sem, sen, seo, and selu2 were encoded on the enterotoxin gene cluster. From these results, we concluded that the two food poisoning outbreaks were SFP cases caused by S. argenteus harboring SE genes. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Beyond Parasitism: Hepatic Lesions in Stranded Harbor Porpoises (Phocoena phocoena) Without Trematode (Campula oblonga) Infections.

    Science.gov (United States)

    Hiemstra, S; Harkema, L; Wiersma, L C M; Keesler, R I

    2015-11-01

    The liver can be an indicator of the health of an individual or of a group, which can be especially important to identify agents that can cause disease in multiple species. To better characterize hepatic lesions in stranded harbor porpoises (Phocoena phocoena), we analyzed the livers from 39 porpoises that stranded along the Dutch coast between December 2008 and December 2012. The animals were selected because they had either gross or histologic liver lesions with minimal autolysis and no evidence of trematode (Campula oblonga) infection. The most common finding was a chronic hepatitis (22/39, 56.4%) that was often associated with significant disease reported in another organ system (18/22, 81.8%), of which 14 had chronic systemic disease. One case of chronic hepatitis was so severe as to mimic lymphoma, which could only be differentiated with immunohistochemistry. The other common lesions were lipidosis (11/39, 28.2%) and acute hepatitis (6/39, 15.4%), often in combination with mild chronic changes. Overall, although there were no consistent trends in etiology for the hepatic lesions, lipidosis was associated with starvation (8/11, 72.7%) and acute disease, and acute hepatitis was associated with bacterial infections and sepsis (6/6, 100%). © The Author(s) 2014.

  19. Virulence of Klebsiella pneumoniae isolates harboring bla KPC-2 carbapenemase gene in a Caenorhabditis elegans model.

    Directory of Open Access Journals (Sweden)

    Jean-Philippe Lavigne

    Full Text Available Klebsiella pneumoniae carbapenemase (KPC is a carbapenemase increasingly reported worldwide in Enterobacteriaceae. The aim of this study was to analyze the virulence of several KPC-2-producing K. pneumoniae isolates. The studied strains were (i five KPC-2 clinical strains from different geographical origins, belonging to different ST-types and possessing plasmids of different incompatibility groups; (ii seven transformants obtained after electroporation of either these natural KPC plasmids or a recombinant plasmid harboring only the bla KPC-2 gene into reference strains K. pneumoniae ATCC10031/CIP53153; and (iii five clinical strains cured of plasmids. The virulence of K. pneumoniae isolates was evaluated in the Caenorhabditis elegans model. The clinical KPC producers and transformants were significantly less virulent (LT50: 5.5 days than K. pneumoniae reference strain (LT50: 4.3 days (p<0.01. However, the worldwide spread KPC-2 positive K. pneumoniae ST258 strains and reference strains containing plasmids extracted from K. pneumoniae ST258 strains had a higher virulence than KPC-2 strains belonging to other ST types (LT50: 5 days vs. 6 days, p<0.01. The increased virulence observed in cured strains confirmed this trend. The bla KPC-2 gene itself was not associated to increased virulence.

  20. Isolation and characterization of a novel arenavirus harbored by Rodents and Shrews in Zhejiang province, China

    Energy Technology Data Exchange (ETDEWEB)

    Li, Kun [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou (China); Lin, Xian-Dan [Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); Wang, Wen [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou (China); Shi, Mang [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Wencheng Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); Guo, Wen-Ping [State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing (China); Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou (China); Zhang, Xiao-He [Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); Xing, Jian-Guang [Wencheng Center for Disease Control and Prevention, Wenzhou, Zhejiang Province (China); and others

    2015-02-15

    To determine the biodiversity of arenaviruses in China, we captured and screened rodents and shrews in Wenzhou city, Zhejiang province, a locality where hemorrhagic fever diseases are endemic in humans. Accordingly, arenaviruses were detected in 42 of 351 rodents from eight species, and in 12 of 272 Asian house shrews (Suncus murinus), by RT-PCR targeting the L segment. From these, a single arenavirus was successfully isolated in cell culture. The virion particles exhibited a typical arenavirus morphology under transmission electron microscopy. Comparison of the S and L segment sequences revealed high levels of nucleotide (>32.2% and >39.6%) and amino acid (>28.8% and >43.8%) sequence differences from known arenaviruses, suggesting that it represents a novel arenavirus, which we designated Wenzhou virus (WENV). Phylogenetic analysis revealed that all WENV strains harbored by both rodents and Asian house shrews formed a distinct lineage most closely related to Old World arenaviruses. - Highlights: • A novel arenavirus (Wenzhou virus) was identified in Zhejiang province, China. • The virus is highly circulating in five species of rats and one species of shrews • More efforts are needed to infer whether it is pathogenic to humans or not.

  1. Meninges harbor cells expressing neural precursor markers during development and adulthood

    Science.gov (United States)

    Bifari, Francesco; Berton, Valeria; Pino, Annachiara; Kusalo, Marijana; Malpeli, Giorgio; Di Chio, Marzia; Bersan, Emanuela; Amato, Eliana; Scarpa, Aldo; Krampera, Mauro; Fumagalli, Guido; Decimo, Ilaria

    2015-01-01

    Brain and skull developments are tightly synchronized, allowing the cranial bones to dynamically adapt to the brain shape. At the brain-skull interface, meninges produce the trophic signals necessary for normal corticogenesis and bone development. Meninges harbor different cell populations, including cells forming the endosteum of the cranial vault. Recently, we and other groups have described the presence in meninges of a cell population endowed with neural differentiation potential in vitro and, after transplantation, in vivo. However, whether meninges may be a niche for neural progenitor cells during embryonic development and in adulthood remains to be determined. In this work we provide the first description of the distribution of neural precursor markers in rat meninges during development up to adulthood. We conclude that meninges share common properties with the classical neural stem cell niche, as they: (i) are a highly proliferating tissue; (ii) host cells expressing neural precursor markers such as nestin, vimentin, Sox2 and doublecortin; and (iii) are enriched in extracellular matrix components (e.g., fractones) known to bind and concentrate growth factors. This study underlines the importance of meninges as a potential niche for endogenous precursor cells during development and in adulthood. PMID:26483637

  2. Recycling steel-manufacturing slag and harbor sediment into construction materials.

    Science.gov (United States)

    Wei, Yu-Ling; Lin, Chang-Yuan; Cheng, Shao-Hsiang; Wang, H Paul

    2014-01-30

    Mixtures consisting of harbor sediment and slag waste from steel industry containing toxic components are fired to produce non-hazardous construction materials. The fired pellets become lighter as firing temperature increases. At a sintering temperature of ≦1050°C, the fired pellets are in a form of brick-like product, while at 1100°C, they become lightweight aggregates. Calcium silicate, kyanite, and cristobalite are newly formed in the pellets after firing, demonstrating that calcium oxide acts as a flux component and chemically reacted with Si- and/or Al-containing components to promote sintering. Dioxin/furan content present in the pure slag is 0.003ng I-TEQg(-1) and, for the fired pellet consisting of slag and sediment, the content appears to be destructed and diminishes to 0.0003ng I-TEQg(-1) after 950°C-firing; while it is 0.002ng I-TEQg(-1) after firing at 1100°C, suggesting that dioxins/furans in the 950°C-fired pellets have a greater chance to escape to atmosphere due to a slower sintering reaction and/or that construction of dioxins/furans from molten chloride salts co-exists with their destruction. Multiple toxicity characteristic leaching procedure extracts Cu, Cr, Zn, Se, Cd, Pb, Ba, As, and Hg from all fired products at negligible levels. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Deep down on a Caribbean reef: lower mesophotic depths harbor a specialized coral-endosymbiont community.

    Science.gov (United States)

    Bongaerts, Pim; Frade, Pedro R; Hay, Kyra B; Englebert, Norbert; Latijnhouwers, Kelly R W; Bak, Rolf P M; Vermeij, Mark J A; Hoegh-Guldberg, Ove

    2015-01-07

    The composition, ecology and environmental conditions of mesophotic coral ecosystems near the lower limits of their bathymetric distributions remain poorly understood. Here we provide the first in-depth assessment of a lower mesophotic coral community (60-100 m) in the Southern Caribbean through visual submersible surveys, genotyping of coral host-endosymbiont assemblages, temperature monitoring and a growth experiment. The lower mesophotic zone harbored a specialized coral community consisting of predominantly Agaricia grahamae, Agaricia undata and a "deep-water" lineage of Madracis pharensis, with large colonies of these species observed close to their lower distribution limit of ~90 m depth. All three species associated with "deep-specialist" photosynthetic endosymbionts (Symbiodinium). Fragments of A. grahamae exhibited growth rates at 60 m similar to those observed for shallow Agaricia colonies (~2-3 cm yr(-1)), but showed bleaching and (partial) mortality when transplanted to 100 m. We propose that the strong reduction of temperature over depth (Δ5°C from 40 to 100 m depth) may play an important contributing role in determining lower depth limits of mesophotic coral communities in this region. Rather than a marginal extension of the reef slope, the lower mesophotic represents a specialized community, and as such warrants specific consideration from science and management.

  4. History of New Bedford Harbor: Ecological consequences of urbanization and implications for remediation

    Energy Technology Data Exchange (ETDEWEB)

    Voyer, R.A.; Pesch, C.; Garber, J.; Cabral, S. [Environmental Protection Agency, Narragansett, RI (United States); Copeland, J.; Comeleo, R. [R.O.W. Sciences, Narragansett, RI (United States)

    1995-12-31

    New Bedford, Massachusetts is the product of {approximately}300 years of agricultural, commercial and industrial activities. Located on the Acushnet River and Buzzard`s Bay, New Bedford is renowned as a former whaling center and former producer of fine quality textiles. It has, however, gained notoriety as a Superfund site contaminated with PCBs. The historical research enhances understanding of sources of cumulative ecological impacts in the Acushnet River estuary. Stressors are reviewed and impacts interpreted in terms of geographic and cultural considerations aided by geographic information system techniques, Analysis of information reveals four sequential developmental periods, each with a distinctive effect an estuarine conditions. Changes in coastline morphology and loss of habitat accompanied wharf building during the whaling period. Wetlands were filled and became building sites during the textile phase. A six-fold population increase between 1870 and 1920 accompanied expansion of textile industry and resulted in increased nutrient loading and raw sewage discharge to the estuary. Shellfish beds were closed throughout estuary in 1904, due to outbreaks of typhoid fever. They remain closed. During the post-textile period, discharge of PCBs further limited fishing in New Bedford and presently restricts harbor restoration. Construction of a hurricane barrier to protect the fishing fleet and city further altered estuarine hydrology. This historical analysis represents a significant adjunct to scientific examination of this site and provides a valuable context for design and conduct of remediation activities.

  5. A recombinant varicella vaccine harboring a respiratory syncytial virus gene induces humoral immunity.

    Science.gov (United States)

    Murakami, Kouki; Matsuura, Masaaki; Ota, Megumi; Gomi, Yasuyuki; Yamanishi, Koichi; Mori, Yasuko

    2015-11-09

    The varicella-zoster virus (VZV) Oka vaccine strain (vOka) is highly efficient and causes few adverse events; therefore, it is used worldwide. We previously constructed recombinant vOka (rvOka) harboring the mumps virus gene. Immunizing guinea pigs with rvOka induced the production of neutralizing antibodies against the mumps virus and VZV. Here, we constructed recombinant vOka viruses containing either the respiratory syncytial virus (RSV) subgroup A fusion glycoprotein (RSV A-F) gene or RSV subgroup B fusion glycoprotein (RSV B-F) gene (rvOka-RSV A-F or rvOka-RSV B-F). Indirect immunofluorescence and Western blot analyses confirmed the expression of each recombinant RSV protein in virus-infected cells. Immunizing guinea pigs with rvOka-RSV A-F or rvOka-RSV B-F led to the induction of antibodies against RSV proteins. These results suggest that the current varicella vaccine genome can be used to generate custom-made vaccine vectors to develop the next generation of live vaccines. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Phytoplankton productivity and biomass in the Charlotte Harbor estuarine system, Florida

    Science.gov (United States)

    McPherson, Benjamin F.; Montgomery, Ralph T.; Emmons, Edward E.

    1990-01-01

    Phytoplankton carbon-14 productivity at a depth of 50 percent of surface light and chlorophyll-a concentrations were measured every other month from November 1985 through September 1986 at 12 stations in the Charlotte Harbor estuarine system. Maximum productivity and chlorophyll-a concentrations occurred during summer or early autumn near the months of tidal rivers. Most of the variability in light-normalized productivity and chlorophyll-a could be attributed to two factors derived from Principal Component Analysis of ambient water-quality characteristics. One factor related to seasonal variability and the other to spatial variability. The seasonal factor incorporated the interaction of temperature and nutrients. The spatial factor incorporated the interaction of salinity, nutrients, and water color that resulted from the mixing of freshwater inflow and seawater. Although freshwater inflow increased the availability of nutrients in low salinity (less than 10 %) waters, the highly colored freshwater restricted light penetration and phytoplankton productivity. Maximum productivity and biomass occurred where color associated with the freshwater inflow had been diluted by seawater so that light and nutrients were both available. Concentrations of inorganic nitrogen were often at or below detection limit throughout most of the high salinity (greater than 20 %) waters of the estuary and was probably the most critical nutrient in limiting phytoplankton productivity.

  7. Predicting the population-level impact of mitigating harbor porpoise bycatch with pingers and time-area fishing closures

    DEFF Research Database (Denmark)

    van Beest, Floris; Kindt-Larsen, Lotte; Bastardie, Francois

    2017-01-01

    efficiency) on the population size using the inner Danish waters as a biological system. The model incorporated empirical data on gillnet fishing effort and noise avoidance behavior by free-ranging harbor porpoises exposed to randomized high-frequency (20- to 160-kHz) pinger signals. The IBM simulations...... and protected marine top predator, involves the use of pingers (acoustic alarms that emit underwater noise) and time-area fishing closures. Although these mitigation measures can reduce harbor porpoise bycatch in gillnet fisheries considerably, inference about the long-term population-level consequences...... revealed a synergistic relationship between the implementation of time-area fishing closures and pinger deployment. Time-area fishing closures reduced bycatch rates substantially but not completely. In contrast, widespread pinger deployment resulted in total mitigation of bycatch but frequent and recurrent...

  8. Multiple-Pulse Sounds and Seals: Results of a Harbor Seal (Phoca vitulina) Telemetry Study During Wind Farm Construction.

    Science.gov (United States)

    Hastie, Gordon D; Russell, Debbie J F; McConnell, Bernie; Thompson, Dave; Janik, Vincent M

    2016-01-01

    Offshore construction and survey techniques can produce pulsed sounds with a high sound pressure level. In coastal waters, the areas in which they are produced are often also used by seals, potentially resulting in auditory damage or behavioral avoidance. Here, we describe a study on harbor seals during a wind farm installation off southeast England. The study used GPS/global system for mobile communication tags on 23 harbor seals that provided distribution and activity data; the closest range of individual seals to piling varied from 6.65 to 46.1 km. Furthermore, the maximum predicted received levels (RLs) at individual seals varied between 146.9 and 169.4 dB re 1 μPa peak to peak.

  9. The effect of a large Danish offshore wind farm on harbor and grey seal haul-out behaviour

    DEFF Research Database (Denmark)

    Edrén, Susi Manuela Clermont; Andersen, Signe May; Teilmann, Jonas

    2010-01-01

    This study investigates the effects of the construction and operation of a large Danish offshore wind farm on harbor and gray seal haul-out behavior within a nearby (4 km) seal sanctuary. Time-lapse photography, visual monitoring, and aerial surveys were used to monitor the number of seals on land...... in daylight hours. Seals were monitored during two preconstruction periods (19 June–31 August 2001 and April–August 2002), a construction period of the wind farm (August 2002–December 2003), and a period of operation of the wind farm (December 2003–December 2004). Monthly aerial surveys were conducted...... to estimate the proportion of seals in the sanctuary relative to neighboring haul-out sites. From preconstruction to construction and through the first year of operation the number of harbor seals in the sanctuary increased at the same rate as the number of seals at the neighboring haul-out sites. No long...

  10. Carbapenem-resistant Escherichia coli harboring Klebsiella pneumoniae carbapenemase beta-lactamases associated with long-term care facilities.

    Science.gov (United States)

    Urban, Carl; Bradford, Patricia A; Tuckman, Margareta; Segal-Maurer, Sorana; Wehbeh, Wehbeh; Grenner, Louise; Colon-Urban, Rita; Mariano, Noriel; Rahal, James J

    2008-06-01

    Nine carbapenem-resistant Escherichia coli isolates harboring Klebsiella pneumoniae carbapenemase (KPC)-2 or KPC-3 enzymes were identified in patients residing in 7 distinct long-term care facilities. Cefotaxime-hydrolyzing (CTX-M)-type beta-lactamases were also documented in 3 isolates. The identification of these enzymes in patients staying in long-term care facilities should be of great concern to all components of health care systems.

  11. Brain transcriptomes of harbor seals demonstrate gene expression patterns of animals undergoing a metabolic disease and a viral infection

    Directory of Open Access Journals (Sweden)

    Stephanie M. Rosales

    2016-12-01

    Full Text Available Diseases of marine mammals can be difficult to diagnose because of their life history and protected status. Stranded marine mammals have been a particularly useful resource to discover and comprehend the diseases that plague these top predators. Additionally, advancements in high-throughput sequencing (HTS has contributed to the discovery of novel pathogens in marine mammals. In this study, we use a combination of HTS and stranded harbor seals (Phoca vitulina to better understand a known and unknown brain disease. To do this, we used transcriptomics to evaluate brain tissues from seven neonatal harbor seals that expired from an unknown cause of death (UCD and compared them to four neonatal harbor seals that had confirmed phocine herpesvirus (PhV-1 infections in the brain. Comparing the two disease states we found that UCD animals showed a significant abundance of fatty acid metabolic transcripts in their brain tissue, thus we speculate that a fatty acid metabolic dysregulation contributed to the death of these animals. Furthermore, we were able to describe the response of four young harbor seals with PhV-1 infections in the brain. PhV-1 infected animals showed a significant ability to mount an innate and adaptive immune response, especially to combat viral infections. Our data also suggests that PhV-1 can hijack host pathways for DNA packaging and exocytosis. This is the first study to use transcriptomics in marine mammals to understand host and viral interactions and assess the death of stranded marine mammals with an unknown disease. Furthermore, we show the value of applying transcriptomics on stranded marine mammals for disease characterization.

  12. Connecting with our waterways: an assessment of public access and stewardship in the New York - New Jersey Harbor Estuary

    Science.gov (United States)

    Kate Boicourt; Robert Pirani; Michelle Johnson; Erika Svendsen; Lindsay K. Campbell

    2016-01-01

    The New York – New Jersey Harbor Estuary is the biggest public space in the nation's largest metropolitan area. Access to its waters – whether for swimming, boating, fishing, or just enjoying the spectacular views – is an amenity that impacts quality of life and drives spending and investments by residents, visitors, and businesses. Park access and use have been...

  13. Tag-based Heart Rate Measurements of Harbor Porpoises During Normal and Noise-exposed Dives to Study Stress Responses

    Science.gov (United States)

    2015-09-30

    nitrogen management and can provide information on the level of stress the animals routinely experience. Here we examine the dive heart rate...ventilation rate and activity in both captive and wild porpoise to better understand the dive response and how it may be overruled by noise exposure. We...acoustic data in captive and wild harbor porpoises. The specific objectives are 1) Quantify the physiological (heart and ventilation rates) and behavioral

  14. Brain transcriptomes of harbor seals demonstrate gene expression patterns of animals undergoing a metabolic disease and a viral infection.

    Science.gov (United States)

    Rosales, Stephanie M; Vega Thurber, Rebecca L

    2016-01-01

    Diseases of marine mammals can be difficult to diagnose because of their life history and protected status. Stranded marine mammals have been a particularly useful resource to discover and comprehend the diseases that plague these top predators. Additionally, advancements in high-throughput sequencing (HTS) has contributed to the discovery of novel pathogens in marine mammals. In this study, we use a combination of HTS and stranded harbor seals (Phoca vitulina) to better understand a known and unknown brain disease. To do this, we used transcriptomics to evaluate brain tissues from seven neonatal harbor seals that expired from an unknown cause of death (UCD) and compared them to four neonatal harbor seals that had confirmed phocine herpesvirus (PhV-1) infections in the brain. Comparing the two disease states we found that UCD animals showed a significant abundance of fatty acid metabolic transcripts in their brain tissue, thus we speculate that a fatty acid metabolic dysregulation contributed to the death of these animals. Furthermore, we were able to describe the response of four young harbor seals with PhV-1 infections in the brain. PhV-1 infected animals showed a significant ability to mount an innate and adaptive immune response, especially to combat viral infections. Our data also suggests that PhV-1 can hijack host pathways for DNA packaging and exocytosis. This is the first study to use transcriptomics in marine mammals to understand host and viral interactions and assess the death of stranded marine mammals with an unknown disease. Furthermore, we show the value of applying transcriptomics on stranded marine mammals for disease characterization.

  15. Molecular methods for the genetic identification of salmonid prey from Pacific harbor seal (Phoca vitulina richardsi) scat

    OpenAIRE

    Purcell, Maureen; Mackey, Greg; LaHood, Eric; Huber, Harriet; Park, Linda

    2004-01-01

    Twenty-six stocks of Pacific salmon and trout (Oncorhynchus spp.), representing evolutionary significant units (ESU), are listed as threatened or endangered under the Endangered Species Act (ESA) and six more stocks are currently being evaluated for listing. The ecological and economic consequences of these listings are large; therefore considerable effort has been made to understand and respond to these declining populations. Until recently, Pacific harbor seals (Phoca vitulina richardsi) on...

  16. HER2 Amplification and Cetuximab Efficacy in Patients With Metastatic Colorectal Cancer Harboring Wild-type RAS and BRAF.

    Science.gov (United States)

    Jeong, Jae Ho; Kim, Jihun; Hong, Yong Sang; Kim, Dalyong; Kim, Jeong Eun; Kim, Sun Young; Kim, Kyu-Pyo; Yoon, Young-Kwang; Kim, Deokhoon; Chun, Sung-Min; Park, Yangsoon; Jang, Se Jin; Kim, Tae Won

    2017-09-01

    Cetuximab has shown clinical benefit in patients with metastatic colorectal cancer (mCRC) harboring wild-type RAS. Human epidermal growth factor receptor 2 (HER2) amplification may be a mechanism of cetuximab resistance. We evaluated the association between HER2 amplification and cetuximab efficacy in patients with mCRC harboring wild-type RAS and BRAF. Between December 2003 and June 2013, we identified 142 patients with mCRC whose tumors harbored both wild-type exons 2, 3, and 4 in KRAS and NRAS, and wild-type exon 15 in BRAF using high throughput sequencing (OncoMap version 4.0). All patients received cetuximab after oxaliplatin, irinotecan, and fluoropyrimidine failure. HER2 status was determined using immunohistochemistry and silver in situ hybridization (SISH) and correlated with cetuximab efficacy. Of 142 RAS and BRAF wild-type tumors, we observed 7 cases (4.9%) of HER2 amplification by SISH. After a median follow-up of 13.2 months (range, 1.4-78.1 months), median progression-free survival (PFS) was significantly different according to HER2 status: 3.1 months in patients with HER2 amplification compared with 5.6 months in those with non-amplified HER2 (hazard ratio, 2.73; 95% confidence interval, 1.18-6.31; P = .019). Overall survival (OS) was not significantly different between groups, although there was a tendency towards shorter OS in patients with HER2-amplified tumors (hazard ratio, 1.31; 95% confidence interval, 0.61-2.82; 10.1 vs. 13.5 months; P = .488). HER2 amplification is predictive of shorter PFS after cetuximab treatment in patients with mCRC harboring wild-type RAS and BRAF. Further study is warranted for this patient population. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Emergence of a multidrug-resistant Citrobacter freundii ST8 harboring an unusual VIM-4 gene cassette in Poland

    Directory of Open Access Journals (Sweden)

    Piotr Majewski

    2017-08-01

    Conclusions: All unusual gene cassettes containing VIM-DR (direct repeat described thus far have been harbored by non-fermenters, i.e., Acinetobacter and Pseudomonas, underscoring the importance of resistance determinant mobility, which may go even beyond genus, family, and order boundaries. Great efforts need to be taken to explore pathways of resistance to ‘last-resort’ antimicrobials, especially among clinically relevant pathogens.

  18. Large-scale Evaluation of Nickel Aluminide Rolls in a Heat-Treat Furnace at Bethelehem Steel's (Now ISG) Burns Harbor Plate Mill

    Energy Technology Data Exchange (ETDEWEB)

    Mengel, J.

    2003-12-16

    At Bethlehem Steel Burns Harbor Plate Division (now ISG Burns Harbor Plate Inc.)'s annealing furnace, new nickel aluminide intermetallic alloy rolls provide greater high-temperature strength and wear resistance compared to the conventional H series cast austenitic alloys currently used in the industry. Oak Ridge National Laboratory and Bethlehem (ISG) partnered under a U.S. Department of Energy, Office of Industrial Technology's Emerging Technology Deployment Program to demonstrate and evaluate the nickel aluminide intermetallic alloy rolls as part of an updated energy efficient large commercial annealing furnace system. Many challenges were involved in this project, including developing welding procedures for joining nickel aluminide intermetallic alloys with H-series austenitic alloys, developing commercial cast roll manufacturing specifications, working with several commercial suppliers to produce a quantity of high quality, reproducible nickel aluminide rolls for a large steel industrial annealing furnace, installing and demonstrating the capability of the rolls in this furnace, performing processing trials to evaluate the benefits of new equipment and processes, and documenting the findings. Updated furnace equipment including twenty-five new automated furnace control dampers have been installed replacing older design, less effective units. These dampers, along with upgraded flame-safety control equipment and new AC motors and roll-speed control equipment, are providing improved furnace control and additional energy efficiency. Energy data shows up to a 34% energy reduction from baseline after the installation of upgraded furnace damper controls along with up to a 34% reduction in greenhouse gases, potential for an additional 3 to 6% energy reduction per campaign of light-up and shutdown, and a 46% energy reduction from baseline for limited trials of a combination of improved damper control and straight-through plate processing. The straight

  19. Pacific lamprey (Entosphenus tridentatus) ammocoetes exposed to contaminated Portland Harbor sediments: Method development and effects on survival, growth, and behavior.

    Science.gov (United States)

    Unrein, Julia R; Morris, Jeffrey M; Chitwood, Rob S; Lipton, Joshua; Peers, Jennifer; van de Wetering, Stan; Schreck, Carl B

    2016-08-01

    Many anthropogenic disturbances have contributed to the decline of Pacific lampreys (Entosphenus tridentatus), but potential negative effects of contaminants on lampreys are unclear. Lamprey ammocoetes are the only detritivorous fish in the lower Willamette River, Oregon, USA, and have been observed in Portland Harbor sediments. Their long benthic larval stage places them at risk from the effects of contaminated sediment. The authors developed experimental methods to assess the effects of contaminated sediment on the growth and behavior of field-collected ammocoetes reared in a laboratory. Specifically, they developed methods to assess individual growth and burrowing behavior. Burrowing performance demonstrated high variability among contaminated sediments; however, ammocoetes presented with noncontaminated reference sediment initiated burrowing more rapidly and completed it faster. Ammocoete reemergence from contaminated sediments suggests avoidance of some chemical compounds. The authors conducted long-term exposure experiments on individually held ammocoetes using sediment collected from their native Siletz River, which included the following: contaminated sediments collected from 9 sites within Portland Harbor, 2 uncontaminated reference sediments collected upstream, 1 uncontaminated sediment with characteristics similar to Portland Harbor sediments, and clean sand. They determined that a 24-h depuration period was sufficient to evaluate weight changes and observed no mortality or growth effects in fish exposed to any of the contaminated sediments. However, the effect on burrowing behavior appeared to be a sensitive endpoint, with potentially significant implications for predator avoidance. Environ Toxicol Chem 2016;35:2092-2102. © 2016 SETAC. © 2016 SETAC.

  20. Predicting dredging-associated effects to coral reefs in Apra Harbor, Guam - Part 1: Sediment exposure modeling.

    Science.gov (United States)

    Gailani, Joseph Z; Lackey, Tahirih C; King, David B; Bryant, Duncan; Kim, Sung-Chan; Shafer, Deborah J

    2016-03-01

    Model studies were conducted to investigate the potential coral reef sediment exposure from dredging associated with proposed development of a deepwater wharf in Apra Harbor, Guam. The Particle Tracking Model (PTM) was applied to quantify the exposure of coral reefs to material suspended by the dredging operations at two alternative sites. Key PTM features include the flexible capability of continuous multiple releases of sediment parcels, control of parcel/substrate interaction, and the ability to efficiently track vast numbers of parcels. This flexibility has facilitated simulating the combined effects of sediment released from clamshell dredging and chiseling within Apra Harbor. Because the rate of material released into the water column by some of the processes is not well understood or known a priori, the modeling approach was to bracket parameters within reasonable ranges to produce a suite of potential results from multiple model runs. Sensitivity analysis to model parameters is used to select the appropriate parameter values for bracketing. Data analysis results include mapping the time series and the maximum values of sedimentation, suspended sediment concentration, and deposition rate. Data were used to quantify various exposure processes that affect coral species in Apra Harbor. The goal of this research is to develop a robust methodology for quantifying and bracketing exposure mechanisms to coral (or other receptors) from dredging operations. These exposure values were utilized in an ecological assessment to predict effects (coral reef impacts) from various dredging scenarios. Copyright © 2015. Published by Elsevier Ltd.