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Sample records for program featuring integrated

  1. Integrated reporting and board features

    OpenAIRE

    Rares HURGHIS

    2017-01-01

    In the last two decades the concept of sustainability reporting gained more importance in the companies’ annual reports, a trend which is embedded also in integrated reporting. Issuing an integrated report became a necessity, because the report explains to the investors how the organization creates value over time. The governance structure, more exactly the board of directors, decides whether or not the company will issue an integrated report. Thus, are there certain features of the board tha...

  2. Integrated reporting and board features

    Directory of Open Access Journals (Sweden)

    Rares HURGHIS

    2017-02-01

    Full Text Available In the last two decades the concept of sustainability reporting gained more importance in the companies’ annual reports, a trend which is embedded also in integrated reporting. Issuing an integrated report became a necessity, because the report explains to the investors how the organization creates value over time. The governance structure, more exactly the board of directors, decides whether or not the company will issue an integrated report. Thus, are there certain features of the board that might influence the issue of an integrated report? Do the companies which issue an integrated report have certain features of the governance structure? Looking for an answer to these questions, we seek for any possible correlations between a disclosure index and the corporate governance structure characteristics, on a sample from the companies participating at the International Integrated Reporting Council Examples Database. The results highlight that only the size of the board influences the extent to which the issued integrated report is in accordance with the International Framework.

  3. Temporal Feature Integration for Music Organisation

    OpenAIRE

    Meng, Anders; Larsen, Jan; Hansen, Lars Kai

    2006-01-01

    This Ph.D. thesis focuses on temporal feature integration for music organisation. Temporal feature integration is the process of combining all the feature vectors of a given time-frame into a single new feature vector in order to capture relevant information in the frame. Several existing methods for handling sequences of features are formulated in the temporal feature integration framework. Two datasets for music genre classification have been considered as valid test-beds for music organisa...

  4. Temporal Feature Integration for Music Organisation

    DEFF Research Database (Denmark)

    Meng, Anders

    2006-01-01

    This Ph.D. thesis focuses on temporal feature integration for music organisation. Temporal feature integration is the process of combining all the feature vectors of a given time-frame into a single new feature vector in order to capture relevant information in the frame. Several existing methods...... for handling sequences of features are formulated in the temporal feature integration framework. Two datasets for music genre classification have been considered as valid test-beds for music organisation. Human evaluations of these, have been obtained to access the subjectivity on the datasets. Temporal...... feature integration has been used for ranking various short-time features at different time-scales. This include short-time features such as the Mel frequency cepstral coefficients (MFCC), linear predicting coding coefficients (LPC) and various MPEG-7 short-time features. The ‘consensus sensitivity...

  5. Temporal feature integration for music genre classification

    DEFF Research Database (Denmark)

    Meng, Anders; Ahrendt, Peter; Larsen, Jan

    2007-01-01

    , but they capture neither the temporal dynamics nor dependencies among the individual feature dimensions. Here, a multivariate autoregressive feature model is proposed to solve this problem for music genre classification. This model gives two different feature sets, the diagonal autoregressive (DAR......) and multivariate autoregressive (MAR) features which are compared against the baseline mean-variance as well as two other temporal feature integration techniques. Reproducibility in performance ranking of temporal feature integration methods were demonstrated using two data sets with five and eleven music genres...

  6. Strategic partnering to improve community health worker programming and performance: features of a community-health system integrated approach.

    Science.gov (United States)

    Naimoli, Joseph F; Perry, Henry B; Townsend, John W; Frymus, Diana E; McCaffery, James A

    2015-09-01

    There is robust evidence that community health workers (CHWs) in low- and middle-income (LMIC) countries can improve their clients' health and well-being. The evidence on proven strategies to enhance and sustain CHW performance at scale, however, is limited. Nevertheless, CHW stakeholders need guidance and new ideas, which can emerge from the recognition that CHWs function at the intersection of two dynamic, overlapping systems - the formal health system and the community. Although each typically supports CHWs, their support is not necessarily strategic, collaborative or coordinated. We explore a strategic community health system partnership as one approach to improving CHW programming and performance in countries with or intending to mount large-scale CHW programmes. To identify the components of the approach, we drew on a year-long evidence synthesis exercise on CHW performance, synthesis records, author consultations, documentation on large-scale CHW programmes published after the synthesis and other relevant literature. We also established inclusion and exclusion criteria for the components we considered. We examined as well the challenges and opportunities associated with implementing each component. We identified a minimum package of four strategies that provide opportunities for increased cooperation between communities and health systems and address traditional weaknesses in large-scale CHW programmes, and for which implementation is feasible at sub-national levels over large geographic areas and among vulnerable populations in the greatest need of care. We postulate that the CHW performance benefits resulting from the simultaneous implementation of all four strategies could outweigh those that either the health system or community could produce independently. The strategies are (1) joint ownership and design of CHW programmes, (2) collaborative supervision and constructive feedback, (3) a balanced package of incentives, and (4) a practical monitoring

  7. Enhanced feature integration in musicians

    DEFF Research Database (Denmark)

    Hansen, Niels Christian; Højlund, Andreas; Møller, Cecilie

    (MEG) from 25 musicians and 25 non-musicians, exposed to sounds presented in interleaved blocks of a musical multi-feature paradigm and a classical oddball control paradigm. In addition to single deviants differing in pitch (P), intensity (I), or perceived location (L), double and triple deviants were...... of MMNms obtained with the constituent single deviants. Significantly greater MMNm under-additivity was observed in musicians compared to non-musicians, specifically for pitch-related deviants in the musical paradigm (i.e. PI, LP, and, marginally, PIL). Conversely, expertise effects were absent from...... the classical oddball control paradigm which used identical sounds. This novel finding supports the dependent processing hypothesis suggesting that musicians recruit overlapping neural resources facilitating more holistic representations of domain-relevant stimuli. These specialised refinements in predictive...

  8. FEATUREOUS: AN INTEGRATED ENVIRONMENT FOR FEATURE-CENTRIC ANALYSIS AND MODIFICATION OF OBJECT-ORIENTED SOFTWARE

    DEFF Research Database (Denmark)

    Olszak, Andrzej; Jørgensen, Bo Nørregaard

    2011-01-01

    software maintenance and evolution, this situation needs to change. In this paper, we present Featureous, an integrated development environment built on top of the NetBeans IDE that facilitates feature-centric analysis of object-oriented software. Our integrated development environment encompasses......The decentralized nature of collaborations between objects in object-oriented software makes it difficult to understand the implementations of user-observable program features and their respective interdependencies. As feature-centric program understanding and modification are essential during...... a lightweight feature location mechanism, a number of reusable analytical views, and necessary APIs for supporting future extensions. The base of the integrated development environment is a conceptual framework comprising of three complementary dimensions of comprehension: perspective, abstraction...

  9. State Program Integrity Reviews

    Data.gov (United States)

    U.S. Department of Health & Human Services — State program integrity reviews play a critical role in how CMS provides effective support and assistance to states in their efforts to combat provider fraud and...

  10. Effective Preparation Program Features: A Literature Review

    Science.gov (United States)

    Crow, Gary M.; Whiteman, Rodney S.

    2016-01-01

    This article is a summary of a report prepared for the University Council for Educational Administration Program Improvement Project for the Wallace Foundation. This explores the research base for educational leadership preparation programs, specifically examining literature on program features. The review covers context, candidates, faculty,…

  11. Remodularizing Java programs for comprehension of features

    DEFF Research Database (Denmark)

    Olszak, Andrzej; Jørgensen, Bo Nørregaard

    2009-01-01

    . In absence of these mechanisms, feature implementations tend to be scattered and tangled in terms of object-oriented abstractions, making the code implementing features difficult to locate and comprehend. In this paper we present a semi-automatic method for feature-oriented remodularization of Java programs....... Our method uses execution traces to locate implementations of features, and Java packages to establish explicit feature modules. To evaluate usefulness of the approach, we present a case study where we apply our method to two real-world software systems. The obtained results indicate a significant...

  12. INTEGRATED INFORMATION SYSTEM ARCHITECTURE PROVIDING BEHAVIORAL FEATURE

    Directory of Open Access Journals (Sweden)

    Vladimir N. Shvedenko

    2016-11-01

    Full Text Available The paper deals with creation of integrated information system architecture capable of supporting management decisions using behavioral features. The paper considers the architecture of information decision support system for production system management. The behavioral feature is given to an information system, and it ensures extraction, processing of information, management decision-making with both automated and automatic modes of decision-making subsystem being permitted. Practical implementation of information system with behavior is based on service-oriented architecture: there is a set of independent services in the information system that provides data of its subsystems or data processing by separate application under the chosen variant of the problematic situation settlement. For creation of integrated information system with behavior we propose architecture including the following subsystems: data bus, subsystem for interaction with the integrated applications based on metadata, business process management subsystem, subsystem for the current state analysis of the enterprise and management decision-making, behavior training subsystem. For each problematic situation a separate logical layer service is created in Unified Service Bus handling problematic situations. This architecture reduces system information complexity due to the fact that with a constant amount of system elements the number of links decreases, since each layer provides communication center of responsibility for the resource with the services of corresponding applications. If a similar problematic situation occurs, its resolution is automatically removed from problem situation metamodel repository and business process metamodel of its settlement. In the business process performance commands are generated to the corresponding centers of responsibility to settle a problematic situation.

  13. Integrated Financial Management Program

    Science.gov (United States)

    Pho, Susan

    2004-01-01

    Having worked in the Employees and Commercial Payments Branch of the Financial Management Division for the past 3 summers, I have seen the many changes that have occurred within the NASA organization. As I return each summer, I find that new programs and systems have been adapted to better serve the needs of the Center and of the Agency. The NASA Agency has transformed itself the past couple years with the implementation of the Integrated Financial Management Program (IFMP). IFMP is designed to allow the Agency to improve its management of its Financial, Physical, and Human Resources through the use of multiple enterprise module applications. With my mentor, Joseph Kan, being the branch chief of the Employees and Commercial Payments Branch, I have been exposed to several modules, such as Travel Manager, WebTads, and Core Financial/SAP, which were implemented in the last couple of years under the IFMP. The implementation of these agency-wide systems has sometimes proven to be troublesome. Prior to IFMP, each NASA Center utilizes their own systems for Payroll, Travel, Accounts Payable, etc. But with the implementation of the Integrated Financial Management Program, all the "legacy" systems had to be eliminated. As a result, a great deal of enhancement and preparation work is necessary to ease the transformation from the old systems to the new. All this work occurs simultaneously; for example, e-Payroll will "go live" in several months, but a system like Travel Manager will need to have information upgraded within the system to meet the requirements set by Headquarters. My assignments this summer have given me the opportunity to become involved with such work. So far, I have been given the opportunity to participate in projects resulting from a congressional request, several bankcard reconciliations, updating routing lists for Travel Manager, updating the majordomo list for Travel Manager approvers and point of contacts, and a NASA Headquarters project involving

  14. State Program Integrity Assessment (SPIA)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The State Program Integrity Assessment (SPIA) is the Centers for Medicare and Medicaid Services (CMS) first national data collection on state Medicaid program...

  15. Tools for Ensuring Program Integrity.

    Science.gov (United States)

    Office of Student Financial Assistance (ED), Washington, DC.

    This training document for financial assistance professionals discusses ensuring program integrity in student financial aid and describes some tools for ensuring internal and external program integrity. The training focuses on these tools and resources: (1) the Federal Student Aid (FSA) Schools Portal; (2) the Information for Financial Aid…

  16. Molecular recognition and self-assembly special feature: Integrative self-sorting is a programming language for high level self-assembly.

    Science.gov (United States)

    Jiang, Wei; Schalley, Christoph A

    2009-06-30

    Starting from the basis of a simple 4-component self-sorting system of crown ethers and ammonium ions, we design 6 building blocks in which 2 identical or different binding sites are incorporated. These building blocks can be mixed in many different ways to yield quite distinctly different pseudorotaxane assemblies. The self-sorting process integrates all building blocks in specific places so that this approach permits us to exert positional control and can widely influence the resulting assemblies with respect to the details of their structures. At maximum, we report quadruply interlocked species with up to 5 subunits that form specific assemblies. Although NMR methods are limited to the analysis of simpler complexes, ESI-MS and, in particular, tandem mass spectrometry is highly useful to analyze the assemblies' connectivities.

  17. Feature Integration Theory Revisited: Dissociating Feature Detection and Attentional Guidance in Visual Search

    Science.gov (United States)

    Chan, Louis K. H.; Hayward, William G.

    2009-01-01

    In feature integration theory (FIT; A. Treisman & S. Sato, 1990), feature detection is driven by independent dimensional modules, and other searches are driven by a master map of locations that integrates dimensional information into salience signals. Although recent theoretical models have largely abandoned this distinction, some observed…

  18. Improving Music Genre Classification by Short Time Feature Integration

    DEFF Research Database (Denmark)

    Meng, Anders; Ahrendt, Peter; Larsen, Jan

    . The problem of making new features on the larger time scale from the short-time features (feature integration) has only received little attention. This paper investigates different methods for feature integration (early information fusion) and late information fusion (assembling of probabilistic outputs......Many different short-time features (derived from 10-30ms of audio) have been proposed for music segmentation, retrieval and genre classification. Often the available time frame of the music to make a decision (the decision time horizon) is in the range of seconds instead of milliseconds...

  19. Improving Music Genre Classification by Short-Time Feature Integration

    DEFF Research Database (Denmark)

    Meng, Anders; Ahrendt, Peter; Larsen, Jan

    2005-01-01

    of seconds instead of milliseconds. The problem of making new features on the larger time scale from the short-time features (feature integration) has only received little attention. This paper investigates different methods for feature integration and late information fusion for music genre classification......Many different short-time features, using time windows in the size of 10-30 ms, have been proposed for music segmentation, retrieval and genre classification. However, often the available time frame of the music to make the actual decision or comparison (the decision time horizon) is in the range...

  20. Steam generator tube integrity program

    Energy Technology Data Exchange (ETDEWEB)

    Dierks, D.R.; Shack, W.J. [Argonne National Laboratory, IL (United States); Muscara, J.

    1996-03-01

    A new research program on steam generator tubing degradation is being sponsored by the U.S. Nuclear Regulatory Commission (NRC) at Argonne National Laboratory. This program is intended to support a performance-based steam generator tube integrity rule. Critical areas addressed by the program include evaluation of the processes used for the in-service inspection of steam generator tubes and recommendations for improving the reliability and accuracy of inspections; validation and improvement of correlations for evaluating integrity and leakage of degraded steam generator tubes, and validation and improvement of correlations and models for predicting degradation in steam generator tubes as aging occurs. The studies will focus on mill-annealed Alloy 600 tubing, however, tests will also be performed on replacement materials such as thermally-treated Alloy 600 or 690. An overview of the technical work planned for the program is given.

  1. Improving Music Genre Classification by Short Time Feature Integration

    OpenAIRE

    Meng, Anders; Ahrendt, Peter; Larsen, Jan

    2005-01-01

    Many different short-time features, using time windows in the size of 10-30 ms, have been proposed for music segmentation, retrieval and genre classification. However, often the available time frame of the music to make the actual decision or comparison (the decision time horizon) is in the range of seconds instead of milliseconds. The problem of making new features on the larger time scale from the short-time features (feature integration) has only received little attention. This paper inves...

  2. Integrating Microcomputing into Preparation Programs.

    Science.gov (United States)

    Peseau, Bruce A.

    This paper presents an example of a course syllabus that integrates the use of microcomputers as part of a recommendation that administrators become specialists in microcomputing in their preparatory programs. Computers' dramatically reduced costs, in combination with increased power, has made them easily available in the form of microcomputers.…

  3. Spatial interactions determine temporal feature integration as revealed by unmasking

    Directory of Open Access Journals (Sweden)

    Michael H. Herzog

    2006-01-01

    Full Text Available Feature integration is one of the most fundamental problems in neuroscience. In a recent contribution, we showed that a trailing grating can diminish the masking effects one vernier exerts on another, preceding vernier. Here, we show that this temporal unmasking depends on neural spatial interactions related to the trailing grating. Hence, our paradigm allows us to study the spatio-temporal interactions underlying feature integration.

  4. EPRI fuel cladding integrity program

    Energy Technology Data Exchange (ETDEWEB)

    Yang, R. [Electric Power Research Institute, Palo Alto, CA (United States)

    1997-01-01

    The objectives of the EPRI fuel program is to supplement the fuel vendor research to assure that utility economic and operational interests are met. To accomplish such objectives, EPRI has conducted research and development efforts to (1) reduce fuel failure rates and mitigate the impact of fuel failures on plant operation, (2) provide technology to extend burnup and reduce fuel cycle cost. The scope of R&D includes fuel and cladding. In this paper, only R&D related to cladding integrity will be covered. Specific areas aimed at improving fuel cladding integrity include: (1) Fuel Reliability Data Base; (2) Operational Guidance for Defective Fuel; (3) Impact of Water Chemistry on Cladding Integrity; (4) Cladding Corrosion Data and Model; (5) Cladding Mechanical Properties; and (6) Transient Fuel Cladding Response.

  5. Integrated Phoneme Subspace Method for Speech Feature Extraction

    Directory of Open Access Journals (Sweden)

    Park Hyunsin

    2009-01-01

    Full Text Available Speech feature extraction has been a key focus in robust speech recognition research. In this work, we discuss data-driven linear feature transformations applied to feature vectors in the logarithmic mel-frequency filter bank domain. Transformations are based on principal component analysis (PCA, independent component analysis (ICA, and linear discriminant analysis (LDA. Furthermore, this paper introduces a new feature extraction technique that collects the correlation information among phoneme subspaces and reconstructs feature space for representing phonemic information efficiently. The proposed speech feature vector is generated by projecting an observed vector onto an integrated phoneme subspace (IPS based on PCA or ICA. The performance of the new feature was evaluated for isolated word speech recognition. The proposed method provided higher recognition accuracy than conventional methods in clean and reverberant environments.

  6. Human detection based on curvelet transform and integrating heterogeneous features

    Science.gov (United States)

    Han, Hong; Fan, Youjian

    2011-06-01

    A method in Curvelet transformation and integrating heterogeneous features for human detection are proposed in this paper. The descriptor based on the second generation Curvelet transform (CTD) was proposed firstly, it concatenated the edge and texture feature vectors. To capture edge features, the statistic measures such as energy, entropy, standard deviation, max value and contrast computed from the blocks which is partitioned from the sub-bands of all the scales are concatenated. To get texture features, the lowest frequency sub-band coefficients were partitioned into overlapped blocks. Four co-occurrence matrixes were computed for each block. And some descriptors such as angular second-moment, contrast, correlation, sum of variance, sum of average and entropy are computed from the co-occurrence matrix, which are concatenated as the texture feature vector. And then the method integrating three feature extraction methods, such as Histogram of Oriented Gradient (HOG), Granularity-tunable Gradients Partition descriptors (GGP), and CTD, is proposed for human detection. Computational Cost Normalized classification Margin is used to determine the order of the feature to be evaluated. The experimental results on the basis of INRIA and MIT human database showed that CTD and integrating heterogeneous feature method increased the detection accuracy comparing to HOG and GGP.

  7. Negative emotion does not modulate rapid feature integration effects

    Directory of Open Access Journals (Sweden)

    Darinka eTruebutschek

    2012-04-01

    Full Text Available Emotional arousal at encoding is known to facilitate later memory recall. In the present study, we asked whether this emotion-modulation of episodic memory is also evident at very short time scales, as measured by feature integration effects, the moment-by-moment binding of relevant stimulus and response features in episodic memory. This question was motivated by recent findings that negative emotion appears to potentiate 1st-order trial sequence effects in classic conflict tasks, which has been attributed to emotion-modulation of conflict-driven cognitive control processes. However, these effects could equally well have been carried by emotion-modulation of mnemonic feature binding processes, which were perfectly confounded with putative control processes in these studies. In the present experiments, we tried to shed light on this question by testing explicitly whether feature integration processes, assessed in isolation of conflict-control, are in fact susceptible to negative emotion-modulation. For this purpose, we adopted a standard protocol for assessing the rapid binding of stimulus and response features in episodic memory (Experiment 1 and paired it with the presentation of either neutral or fearful background face stimuli, shown either at encoding only (Experiment 2, or at both encoding and retrieval (Experiment 3. Whereas reliable feature integration effects were observed in all three experiments, no evidence for emotion-modulation of these effects was detected, in spite of significant effects of emotion on response times. These findings suggest that rapid feature integration of foreground stimulus and response features is not subject to modulation by negative emotional background stimuli and further suggest that previous reports of emotion-modulated trial-transition effects are likely attributable to the effects of emotion on cognitive control processes.

  8. Dissociating conflict adaptation from feature integration: a multiple regression approach.

    Science.gov (United States)

    Notebaert, Wim; Verguts, Tom

    2007-10-01

    Congruency effects are typically smaller after incongruent than after congruent trials. One explanation is in terms of higher levels of cognitive control after detection of conflict (conflict adaptation; e.g., M. M. Botvinick, T. S. Braver, D. M. Barch, C. S. Carter, & J. D. Cohen, 2001). An alternative explanation for these results is based on feature repetition and/or integration effects (e.g., B. Hommel, R. W. Proctor, & K.-P. Vu, 2004; U. Mayr, E. Awh, & P. Laurey, 2003). Previous attempts to dissociate feature integration from conflict adaptation focused on a particular subset of the data in which feature transitions were held constant (J. G. Kerns et al., 2004) or in which congruency transitions were held constant (C. Akcay & E. Hazeltine, in press), but this has a number of disadvantages. In this article, the authors present a multiple regression solution for this problem and discuss its possibilities and pitfalls. (c) 2007 APA

  9. An integrated feature ranking and selection framework for ADHD characterization.

    Science.gov (United States)

    Xiao, Cao; Bledsoe, Jesse; Wang, Shouyi; Chaovalitwongse, Wanpracha Art; Mehta, Sonya; Semrud-Clikeman, Margaret; Grabowski, Thomas

    2016-09-01

    Today, diagnosis of attention deficit hyperactivity disorder (ADHD) still primarily relies on a series of subjective evaluations that highly rely on a doctor's experiences and intuitions from diagnostic interviews and observed behavior measures. An accurate and objective diagnosis of ADHD is still a challenge and leaves much to be desired. Many children and adults are inappropriately labeled with ADHD conditions, whereas many are left undiagnosed and untreated. Recent advances in neuroimaging studies have enabled us to search for both structural (e.g., cortical thickness, brain volume) and functional (functional connectivity) abnormalities that can potentially be used as new biomarkers of ADHD. However, structural and functional characteristics of neuroimaging data, especially magnetic resonance imaging (MRI), usually generate a large number of features. With a limited sample size, traditional machine learning techniques can be problematic to discover the true characteristic features of ADHD due to the significant issues of overfitting, computational burden, and interpretability of the model. There is an urgent need of efficient approaches to identify meaningful discriminative variables from a higher dimensional feature space when sample size is small compared with the number of features. To tackle this problem, this paper proposes a novel integrated feature ranking and selection framework that utilizes normalized brain cortical thickness features extracted from MRI data to discriminate ADHD subjects against healthy controls. The proposed framework combines information theoretic criteria and the least absolute shrinkage and selection operator (Lasso) method into a two-step feature selection process which is capable of selecting a sparse model while preserving the most informative features. The experimental results showed that the proposed framework generated the highest/comparable ADHD prediction accuracy compared with the state-of-the-art feature selection

  10. Features of integrative process in formation of the Arctic region

    OpenAIRE

    Nadezhda Kharlampeva

    2013-01-01

    Features of integrative process in formation of the Arctic region Nadezhda Kharlampieva, Saint-Petersburg State University Article is devoted to the Arctic - the new region of contemporary international relations system where global issues of world politics are solved. Discussion around the Arctic in the early 21st century can be characterized within four policy-academic thesis formulated by contemporary development and 'open region' concepts. From the view point of world political analysis, ...

  11. Feature extraction from multiple data sources using genetic programming.

    Energy Technology Data Exchange (ETDEWEB)

    Szymanski, J. J. (John J.); Brumby, Steven P.; Pope, P. A. (Paul A.); Eads, D. R. (Damian R.); Galassi, M. C. (Mark C.); Harvey, N. R. (Neal R.); Perkins, S. J. (Simon J.); Porter, R. B. (Reid B.); Theiler, J. P. (James P.); Young, A. C. (Aaron Cody); Bloch, J. J. (Jeffrey J.); David, N. A. (Nancy A.); Esch-Mosher, D. M. (Diana M.)

    2002-01-01

    Feature extration from imagery is an important and long-standing problem in remote sensing. In this paper, we report on work using genetic programming to perform feature extraction simultaneously from multispectral and digital elevation model (DEM) data. The tool used is the GENetic Imagery Exploitation (GENIE) software, which produces image-processing software that inherently combines spatial and spectral processing. GENIE is particularly useful in exploratory studies of imagery, such as one often does in combining data from multiple sources. The user trains the software by painting the feature of interest with a simple graphical user interface. GENIE then uses genetic programming techniques to produce an image-processing pipeline. Here, we demonstrate evolution of image processing algorithms that extract a range of land-cover features including towns, grasslands, wild fire burn scars, and several types of forest. We use imagery from the DOE/NNSA Multispectral Thermal Imager (MTI) spacecraft, fused with USGS 1:24000 scale DEM data.

  12. Feature Scaling via Second-Order Cone Programming

    Directory of Open Access Journals (Sweden)

    Zhizheng Liang

    2016-01-01

    Full Text Available Feature scaling has attracted considerable attention during the past several decades because of its important role in feature selection. In this paper, a novel algorithm for learning scaling factors of features is proposed. It first assigns a nonnegative scaling factor to each feature of data and then adopts a generalized performance measure to learn the optimal scaling factors. It is of interest to note that the proposed model can be transformed into a convex optimization problem: second-order cone programming (SOCP. Thus the scaling factors of features in our method are globally optimal in some sense. Several experiments on simulated data, UCI data sets, and the gene data set are conducted to demonstrate that the proposed method is more effective than previous methods.

  13. Alaska Program Point and Line Feature GIS Data from COMIDA, ANIMIDA and cANIMIDA Programs

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — Alaska Program Map Service contains point and line features from the following BOEM Alaska Region environmental monitoring programs: Chukchi Sea Offshore Monitoring...

  14. Integrating Features of Islamic Traditional Home and Smart Home

    Directory of Open Access Journals (Sweden)

    Mona El Basyouni

    2017-06-01

    Full Text Available Architecture is a mirror that reflects the various elements of its environment and surroundings, such as climate, geographical characteristics, standard architectural principles, and social, cultural and scientific developments. Muslims of different regions were able, through architecture, to portray their temperaments and environments, free of external influence and guarantee life goals for users. Every day, building owners and occupants experience the constant challenges of comfort, convenience, cost, productivity, performance and sustainability. Owners, designers, builders, and operators are continuously faced with new processes, technologies and offerings to help them achieve better building performance. Since an intelligent building is run by a “system of systems” that is integrated to deliver a higher level of operational efficiency and an improved set of user-interface tools than are usually found in traditional building automation; at the other hand Arab homes with Islamic Identity guarantee all life goals for use.. Hence, this research focus on the smart environmental treatments of Islamic features for traditional architecture in Arabs homes, features of smart home and life goals for resident users.Trying to achieve a methodology combining them for enriching Arab experience of traditional architecture and its architectural results, with the modern trends of smart architecture. This combination aims at creating a residential model combining the benefits and features of Arab Islamic identity and intelligent design.

  15. State Program Integrity Review Reports List

    Data.gov (United States)

    U.S. Department of Health & Human Services — Comprehensive state program integrity (PI) review reports (and respective follow-up review reports) provide CMS assessment of the effectiveness of the states PI...

  16. Integrating Multi-omic features exploiting Chromosome Conformation Capture data

    Directory of Open Access Journals (Sweden)

    Ivan eMerelli

    2015-02-01

    Full Text Available The representation, integration and interpretation of omic data is a complex task, in particular considering the huge amount of information that is daily produced in molecular biology laboratories all around the world. The reason is that sequencing data regarding expression profiles, methylation patterns, and chromatin domains is difficult to harmonize in a systems biology view, since genome browsers only allow coordinate-based representations, discarding functional clusters created by the spatial conformation of the DNA in the nucleus. In this context, recent progresses in high throughput molecular biology techniques and bioinformatics have provided insights into chromatin interactions on a larger scale and offer a formidable support for the interpretation of multi-omic data. In particular, a novel sequencing technique called Chromosome Conformation Capture (3C allows the analysis of the chromosome organization in the cell’s natural state. While performed genome wide, this technique is usually called Hi-C. Inspired by service applications such as Google Maps, we developed NuChart, an R package that integrates Hi-C data to describe the chromosomal neighbourhood starting from the information about gene positions, with the possibility of mapping on the achieved graphs genomic features such as methylation patterns and histone modifications, along with expression profiles. In this paper we show the importance of the NuChart application for the integration of multi-omic data in a systems biology fashion, with particular interest in cytogenetic applications of these techniques. Moreover, we demonstrate how the integration of multi-omic data can provide useful information in understanding why genes are in certain specific positions inside the nucleus and how epigenetic patterns correlate with their expression.

  17. Aura: A Multi-Featured Programming Framework in Python

    Directory of Open Access Journals (Sweden)

    2010-09-01

    Full Text Available This paper puts forward the design, programming and application of innovative educational software, ‘Aura’ made using Python and PyQt Python bindings. The research paper presents a new concept of using a single tool to relate between syntaxes of various programming languages and algorithms. It radically increases their understanding and retaining capacity, since they can correlate between many programming languages. The software is a totally unorthodox attempt towards helping students who have their first tryst with programming languages. The application is designed to help students understand how algorithms work and thus, help them in learning multiple programming languages on a single platform using an interactive graphical user interface. This paper elucidates how using Python and PyQt bindings, a comprehensive feature rich application, that implements an interactive algorithm building technique, a web browser, multiple programming language framework, a code generator and a real time code sharing hub be embedded into a single interface. And also explains, that using Python as building tool, it requires much less coding than conventional feature rich applications coded in other programming languages, and at the same time does not compromise on stability, inter-operability and robustness of the application.

  18. Marine Structural Integrity Programs (MSIP).

    Science.gov (United States)

    1991-10-01

    Assuming a useful lifetime of 20 years, PFoa (average annual) = 2 x 10-3 or 0.2 % per year. The MSIP IMR program that could develop Pfoa in the range of...Basar and Roderick B. Hulla 1990 SSC-362 Shipboard Wave Height Sensor by R. Atwater 1990 SSC-363 Uncertainties in Stress Analysis on Marine Structures

  19. [An integrated program for psychosis].

    Science.gov (United States)

    Marconi Tassara, J; Diaz, J P; Mourgues, C

    1980-09-01

    The reciprocal balance between the cognitive normal awareness of reality and the cognitive psychotic awareness of reality in schizophrenia, is proposed, on the basis of the structural psychopathological theory of psychoses of the author. This balance points to the dominance of the operant conditioning of psychotic reality over normal reality during the invasion period of the disease, an equilibrium of both aspects during the steady period, and a dominance of normal reality during the residual period. A comprehensive program for secondary and terciary prevention of schizophrenia is outlined, with five levels of function delegation: D1, psychiatrists and psychologists; D2, nurses and social workers; D3, auxiliary nurses; D4, family co-therapist; D5, patients and other relatives. The functions delegated to D5 include the recognition of symptoms, causes and course, and attitudes conducing to secondary handicaps in patients. To D4, are delegate the administration of psychotropic drugs at home and technique for reinforcing normal reality. To D3, are delegated notions on epidemiology, the supervision of the psychopharmacological treatment and of reinforcement programs for normal reality, attitudes and its change, and notions of urgencies in psychosis. The D2 and D1 levels indicate treatment at all levels and treat the more complicated cases in institutions. The efficacy of the program in 36 cases, after a year, indicates a reduction of acute psychotic productivity from 72 to 6% of the patients, and a rate of hospitalization of only 8%.

  20. Mall Walking Program Environments, Features, and Participants: A Scoping Review.

    Science.gov (United States)

    Farren, Laura; Belza, Basia; Allen, Peg; Brolliar, Sarah; Brown, David R; Cormier, Marc L; Janicek, Sarah; Jones, Dina L; King, Diane K; Marquez, David X; Rosenberg, Dori E

    2015-08-13

    Walking is a preferred and recommended physical activity for middle-aged and older adults, but many barriers exist, including concerns about safety (ie, personal security), falling, and inclement weather. Mall walking programs may overcome these barriers. The purpose of this study was to summarize the evidence on the health-related value of mall walking and mall walking programs. We conducted a scoping review of the literature to determine the features, environments, and benefits of mall walking programs using the RE-AIM framework (reach, effectiveness, adoption, implementation, and maintenance). The inclusion criteria were articles that involved adults aged 45 years or older who walked in indoor or outdoor shopping malls. Exclusion criteria were articles that used malls as laboratory settings or focused on the mechanics of walking. We included published research studies, dissertations, theses, conference abstracts, syntheses, nonresearch articles, theoretical papers, editorials, reports, policy briefs, standards and guidelines, and nonresearch conference abstracts and proposals. Websites and articles written in a language other than English were excluded. We located 254 articles on mall walking; 32 articles met our inclusion criteria. We found that malls provided safe, accessible, and affordable exercise environments for middle-aged and older adults. Programmatic features such as program leaders, blood pressure checks, and warm-up exercises facilitated participation. Individual benefits of mall walking programs included improvements in physical, social, and emotional well-being. Limited transportation to the mall was a barrier to participation. We found the potential for mall walking programs to be implemented in various communities as a health promotion measure. However, the research on mall walking programs is limited and has weak study designs. More rigorous research is needed to define best practices for mall walking programs' reach, effectiveness, adoption

  1. Featureous: an Integrated Approach to Location, Analysis and Modularization of Features in Java Applications

    DEFF Research Database (Denmark)

    Olszak, Andrzej

    of features in Java applications. Featureous addresses these concerns in four steps. Firstly, a dynamic method based on so-called feature-entry points is used to establish traceability links between features and their corresponding source code units. Secondly, this traceability forms a basis for a feature......-oriented analysis method that visualizes and measures features. Thirdly, scattering and tangling of features can be physically reduced using feature-oriented remodularization method that is based on multi-objective optimization of Java package structures. Finally, automated detection of so-called feature seed...... methods is proposed, to enable large-scale feature-oriented quality assessment. Featureous is implemented as a plugin to the NetBeans IDE. This implementation was used to evaluate the constituent methods of Featureous by applying them to several medium and large open-source Java systems. The gathered...

  2. Genetic programming approach to extracting features from remotely sensed imagery

    Energy Technology Data Exchange (ETDEWEB)

    Theiler, J. P. (James P.); Perkins, S. J. (Simon J.); Harvey, N. R. (Neal R.); Szymanski, J. J. (John J.); Brumby, Steven P.

    2001-01-01

    Multi-instrument data sets present an interesting challenge to feature extraction algorithm developers. Beyond the immediate problems of spatial co-registration, the remote sensing scientist must explore a complex algorithm space in which both spatial and spectral signatures may be required to identify a feature of interest. We describe a genetic programming/supervised classifier software system, called Genie, which evolves and combines spatio-spectral image processing tools for remotely sensed imagery. We describe our representation of candidate image processing pipelines, and discuss our set of primitive image operators. Our primary application has been in the field of geospatial feature extraction, including wildfire scars and general land-cover classes, using publicly available multi-spectral imagery (MSI) and hyper-spectral imagery (HSI). Here, we demonstrate our system on Landsat 7 Enhanced Thematic Mapper (ETM+) MSI. We exhibit an evolved pipeline, and discuss its operation and performance.

  3. Mall Walking Program Environments, Features, and Participants: A Scoping Review

    Science.gov (United States)

    Belza, Basia; Allen, Peg; Brolliar, Sarah; Brown, David R.; Cormier, Marc L.; Janicek, Sarah; Jones, Dina L.; King, Diane K.; Marquez, David X.; Rosenberg, Dori E.

    2015-01-01

    Introduction Walking is a preferred and recommended physical activity for middle-aged and older adults, but many barriers exist, including concerns about safety (ie, personal security), falling, and inclement weather. Mall walking programs may overcome these barriers. The purpose of this study was to summarize the evidence on the health-related value of mall walking and mall walking programs. Methods We conducted a scoping review of the literature to determine the features, environments, and benefits of mall walking programs using the RE-AIM framework (reach, effectiveness, adoption, implementation, and maintenance). The inclusion criteria were articles that involved adults aged 45 years or older who walked in indoor or outdoor shopping malls. Exclusion criteria were articles that used malls as laboratory settings or focused on the mechanics of walking. We included published research studies, dissertations, theses, conference abstracts, syntheses, nonresearch articles, theoretical papers, editorials, reports, policy briefs, standards and guidelines, and nonresearch conference abstracts and proposals. Websites and articles written in a language other than English were excluded. Results We located 254 articles on mall walking; 32 articles met our inclusion criteria. We found that malls provided safe, accessible, and affordable exercise environments for middle-aged and older adults. Programmatic features such as program leaders, blood pressure checks, and warm-up exercises facilitated participation. Individual benefits of mall walking programs included improvements in physical, social, and emotional well-being. Limited transportation to the mall was a barrier to participation. Conclusion We found the potential for mall walking programs to be implemented in various communities as a health promotion measure. However, the research on mall walking programs is limited and has weak study designs. More rigorous research is needed to define best practices for mall walking

  4. Integration of Feature Calibration and Alignment into ACAPS

    Science.gov (United States)

    Woods, B. K.; Nehrkorn, T.

    2011-12-01

    In support of the National Center for Atmospheric Research (NCAR) development of the Air Force Weather Agency (AFWA) Coupled Analysis and Prediction System (ACAPS), a data assimilation preprocessor was developed to displace model fields using Feature Calibration and Alignment (FCA; Hoffman et al., 1995). A Fotran90 API was written to apply FCA displacements to WRF input as a preprocessor for 4DVar. A modified version of the vortex relocation scheme of Hsiao et al. (2010) was applied to maintain dynamical balance. Unlike Hsiao et al. (2010), sea level pressure was displaced rather than surface pressure, and relative humidity was used in the displacement in lieu of water vapor mixing ratio. A time-lagged test was run using the Hurricane Katrina default WRF case. The 12-hour control forecast was used as pseudo-observations to displace the 6-hour control forecast forward along the hurricane's track. After completing an additional 18-hour integration (for a total of 24 hours), the hurricane maintained its forward displaced position. The modifications of Hsiao's algorithm allowed for the application of displacement across the entire model domain rather than only over flat areas and significantly reduced terrain-induced artifacts.

  5. Music Genre Classification using the multivariate AR feature integration model

    DEFF Research Database (Denmark)

    Ahrendt, Peter; Meng, Anders

    2005-01-01

    informative decisions about musical genre. For the MIREX music genre contest several authors derive long time features based either on statistical moments and/or temporal structure in the short time features. In our contribution we model a segment (1.2 s) of short time features (texture) using a multivariate......Music genre classification systems are normally build as a feature extraction module followed by a classifier. The features are often short-time features with time frames of 10-30ms, although several characteristics of music require larger time scales. Thus, larger time frames are needed to take...

  6. Systems Engineering and Integration for Technology Programs

    Science.gov (United States)

    Kennedy, Kruss J.

    2006-01-01

    The Architecture, Habitability & Integration group (AH&I) is a system engineering and integration test team within the NASA Crew and Thermal Systems Division (CTSD) at Johnson Space Center. AH&I identifies and resolves system-level integration issues within the research and technology development community. The timely resolution of these integration issues is fundamental to the development of human system requirements and exploration capability. The integration of the many individual components necessary to construct an artificial environment is difficult. The necessary interactions between individual components and systems must be approached in a piece-wise fashion to achieve repeatable results. A formal systems engineering (SE) approach to define, develop, and integrate quality systems within the life support community has been developed. This approach will allow a Research & Technology Program to systematically approach the development, management, and quality of technology deliverables to the various exploration missions. A tiered system engineering structure has been proposed to implement best systems engineering practices across all development levels from basic research to working assemblies. These practices will be implemented through a management plan across all applicable programs, projects, elements and teams. While many of the engineering practices are common to other industries, the implementation is specific to technology development. An accounting of the systems engineering management philosophy will be discussed and the associated programmatic processes will be presented.

  7. Integrating Pareto Optimization into Dynamic Programming

    Directory of Open Access Journals (Sweden)

    Thomas Gatter

    2016-01-01

    Full Text Available Pareto optimization combines independent objectives by computing the Pareto front of the search space, yielding a set of optima where none scores better on all objectives than any other. Recently, it was shown that Pareto optimization seamlessly integrates with algebraic dynamic programming: when scoring schemes A and B can correctly evaluate the search space via dynamic programming, then so can Pareto optimization with respect to A and B. However, the integration of Pareto optimization into dynamic programming opens a wide range of algorithmic alternatives, which we study in substantial detail in this article, using real-world applications in biosequence analysis, a field where dynamic programming is ubiquitous. Our results are two-fold: (1 We introduce the operation of a “Pareto algebra product” in the dynamic programming framework of Bellman’s GAP. Users of this framework can now ask for Pareto optimization with a single keystroke. Careful evaluation of the implementation alternatives by means of an extended Bellman’s GAP compiler demonstrates the dependence of the best implementation choice on the application at hand. (2 We extract from our experiments several pieces of advice to programmers who do not use a system such as Bellman’s GAP, but who choose to hand-craft their dynamic programming recurrences, incorporating Pareto optimization from scratch.

  8. Evidence for Optimal Integration of Visual Feature Representations across Saccades.

    Science.gov (United States)

    Oostwoud Wijdenes, Leonie; Marshall, Louise; Bays, Paul M

    2015-07-15

    We explore the visual world through saccadic eye movements, but saccades also present a challenge to visual processing by shifting externally stable objects from one retinal location to another. The brain could solve this problem in two ways: by overwriting preceding input and starting afresh with each fixation or by maintaining a representation of presaccadic visual features in working memory and updating it with new information from the remapped location. Crucially, when multiple objects are present in a scene the planning of eye movements profoundly affects the precision of their working memory representations, transferring limited memory resources from fixation toward the saccade target. Here we show that when humans make saccades, it results in an update of not just the precision of representations but also their contents. When multiple item colors are shifted imperceptibly during a saccade the perceived colors are found to fall between presaccadic and postsaccadic values, with the weight given to each input varying continuously with item location, and fixed relative to saccade parameters. Increasing sensory uncertainty, by adding color noise, biases updating toward the more reliable input, which is consistent with an optimal integration of presaccadic working memory with a postsaccadic updating signal. We recover this update signal and show it to be tightly focused on the vicinity of the saccade target. These results reveal how the nervous system accumulates detailed visual information from multiple views of the same object or scene. This study examines the consequences of saccadic eye movements for the internal representation of visual objects. A saccade shifts the image of a stable visual object from one part of the retina to another. We show that visual representations are built up over these different views of the same object, by combining information obtained before and after each saccade. The weights given to presaccadic and postsaccadic information are

  9. Integrated Active and Passive Polymer Optical Components with nm to mm Features

    OpenAIRE

    Christiansen, Mads Brøkner; Schøler, Mikkel; Kristensen, Anders

    2007-01-01

    We present wafer-scale fabrication of integrated active and passive polymer optics with nm to mm features. First order DFB lasers, defined in dye doped SU-8 resist are integrated with SU-8 waveguides.

  10. Integrated Data Base Program: a status report

    Energy Technology Data Exchange (ETDEWEB)

    Notz, K.J.; Klein, J.A.

    1984-06-01

    The Integrated Data Base (IDB) Program provides official Department of Energy (DOE) data on spent fuel and radioactive waste inventories, projections, and characteristics. The accomplishments of FY 1983 are summarized for three broad areas: (1) upgrading and issuing of the annual report on spent fuel and radioactive waste inventories, projections, and characteristics, including ORIGEN2 applications and a quality assurance plan; (2) creation of a summary data file in user-friendly format for use on a personal computer and enhancing user access to program data; and (3) optimizing and documentation of the data handling methodology used by the IDB Program and providing direct support to other DOE programs and sites in data handling. Plans for future work in these three areas are outlined. 23 references, 11 figures.

  11. Evaluating Pain Education Programs: An Integrated Approach

    Directory of Open Access Journals (Sweden)

    Adam Dubrowski

    2011-01-01

    Full Text Available Evaluation of educational programs and assessment of learning are essential to maintain high-standard health science education, which includes pain education. Current models of program evaluations applied to the education of the health professions, such as the Kirkpatrick model, are mainly outcome based. More recently, efforts have been made to examine other process-based models such as the Context Input Process Product model. The present article proposes an approach that integrates both outcome- and process-based models with models of clinical performance assessment to provide a deeper understanding of a program function. Because assessment instruments are a critical part of program evaluation, it is suggested that standardization and rigour should be used in their selection, development and adaptation. The present article suggests an alternative to currently used models in pain education evaluation.

  12. Integrated Active and Passive Polymer Optical Components with nm to mm Features

    DEFF Research Database (Denmark)

    Christiansen, Mads Brøkner; Schøler, Mikkel; Kristensen, Anders

    2007-01-01

    We present wafer-scale fabrication of integrated active and passive polymer optics with nm to mm features. First order DFB lasers, defined in dye doped SU-8 resist are integrated with SU-8 waveguides.......We present wafer-scale fabrication of integrated active and passive polymer optics with nm to mm features. First order DFB lasers, defined in dye doped SU-8 resist are integrated with SU-8 waveguides....

  13. Microdevelopment of Complex Featural and Spatial Integration with Contextual Support

    Directory of Open Access Journals (Sweden)

    Pamela L. Hirsch

    2015-01-01

    Full Text Available Complex spatial decisions involve the ability to combine featural and spatial information in a scene. In the present work, 4- through 9-year-old children completed a complex map-scene correspondence task under baseline and supported conditions. Children compared a photographed scene with a correct map and with map-foils that made salient an object feature or spatial property. Map-scene matches were analyzed for the effects of age and featural-spatial information on children’s selections. In both conditions children significantly favored maps that highlighted object detail and object perspective rather than color, landmark, and metric elements. Children’s correct performance did not differ by age and was suboptimal, but their ability to choose correct maps improved significantly when contextual support was provided. Strategy variability was prominent for all age groups, but at age 9 with support children were more likely to give up their focus on features and transition to the use of spatial strategies. These findings suggest the possibility of a U-shaped curve for children’s development of geometric knowledge: geometric coding is predominant early on, diminishes for a time in middle childhood in favor of a preference for features, and then reemerges along with the more advanced abilities to combine featural and spatial information.

  14. Feature selection for high-dimensional integrated data

    KAUST Repository

    Zheng, Charles

    2012-04-26

    Motivated by the problem of identifying correlations between genes or features of two related biological systems, we propose a model of feature selection in which only a subset of the predictors Xt are dependent on the multidimensional variate Y, and the remainder of the predictors constitute a “noise set” Xu independent of Y. Using Monte Carlo simulations, we investigated the relative performance of two methods: thresholding and singular-value decomposition, in combination with stochastic optimization to determine “empirical bounds” on the small-sample accuracy of an asymptotic approximation. We demonstrate utility of the thresholding and SVD feature selection methods to with respect to a recent infant intestinal gene expression and metagenomics dataset.

  15. An integrated database with system optimization and design features

    Science.gov (United States)

    Arabyan, A.; Nikravesh, P. E.; Vincent, T. L.

    1992-01-01

    A customized, mission-specific relational database package was developed to allow researchers working on the Mars oxygen manufacturing plant to enter physical description, engineering, and connectivity data through a uniform, graphical interface and to store the data in formats compatible with other software also developed as part of the project. These latter components include an optimization program to maximize or minimize various criteria as the system evolves into its final design; programs to simulate the behavior of various parts of the plant in Martian conditions; an animation program which, in different modes, provides visual feedback to designers and researchers about the location of and temperature distribution among components as well as heat, mass, and data flow through the plant as it operates in different scenarios; and a control program to investigate the stability and response of the system under different disturbance conditions. All components of the system are interconnected so that changes entered through one component are reflected in the others.

  16. A Multiobjective Genetic Programming-Based Ensemble for Simultaneous Feature Selection and Classification.

    Science.gov (United States)

    Nag, Kaustuv; Pal, Nikhil R

    2016-02-01

    We present an integrated algorithm for simultaneous feature selection (FS) and designing of diverse classifiers using a steady state multiobjective genetic programming (GP), which minimizes three objectives: 1) false positives (FPs); 2) false negatives (FNs); and 3) the number of leaf nodes in the tree. Our method divides a c -class problem into c binary classification problems. It evolves c sets of genetic programs to create c ensembles. During mutation operation, our method exploits the fitness as well as unfitness of features, which dynamically change with generations with a view to using a set of highly relevant features with low redundancy. The classifiers of i th class determine the net belongingness of an unknown data point to the i th class using a weighted voting scheme, which makes use of the FP and FN mistakes made on the training data. We test our method on eight microarray and 11 text data sets with diverse number of classes (from 2 to 44), large number of features (from 2000 to 49 151), and high feature-to-sample ratio (from 1.03 to 273.1). We compare our method with a bi-objective GP scheme that does not use any FS and rule size reduction strategy. It depicts the effectiveness of the proposed FS and rule size reduction schemes. Furthermore, we compare our method with four classification methods in conjunction with six features selection algorithms and full feature set. Our scheme performs the best for 380 out of 474 combinations of data sets, algorithm and FS method.

  17. Features of integrated professional training for physically disabled ...

    African Journals Online (AJOL)

    Background: The rehabilitation of physically disabled people has been explored from the perspectives of patients, health professionals, rehabilitation agencies, etc. However, no study has linked disability types, training programmes and career prospects. In this study, we therefore evaluated the professional integration of ...

  18. Integrated visual analysis of protein structures, sequences, and feature data.

    Science.gov (United States)

    Stolte, Christian; Sabir, Kenneth S; Heinrich, Julian; Hammang, Christopher J; Schafferhans, Andrea; O'Donoghue, Seán I

    2015-01-01

    To understand the molecular mechanisms that give rise to a protein's function, biologists often need to (i) find and access all related atomic-resolution 3D structures, and (ii) map sequence-based features (e.g., domains, single-nucleotide polymorphisms, post-translational modifications) onto these structures. To streamline these processes we recently developed Aquaria, a resource offering unprecedented access to protein structure information based on an all-against-all comparison of SwissProt and PDB sequences. In this work, we provide a requirements analysis for several frequently occuring tasks in molecular biology and describe how design choices in Aquaria meet these requirements. Finally, we show how the interface can be used to explore features of a protein and gain biologically meaningful insights in two case studies conducted by domain experts. The user interface design of Aquaria enables biologists to gain unprecedented access to molecular structures and simplifies the generation of insight. The tasks involved in mapping sequence features onto structures can be conducted easier and faster using Aquaria.

  19. In Situ Remediation Integrated Program: FY 1994 program summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    The US Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of the Office of Environmental Management (EM) in November 1989. In an effort to focus resources and address priority needs, EM-50 introduced the concept of integrated programs (IPs) and integrated demonstrations (IDs). The In Situ Remediation Integrated Program (ISR IP) focuses research and development on the in-place treatment of contaminated environmental media, such as soil and groundwater, and the containment of contaminants to prevent the contaminants from spreading through the environment. Using in situ remediation technologies to clean up DOE sites minimizes adverse health effects on workers and the public by reducing contact exposure. The technologies also reduce cleanup costs by orders of magnitude. This report summarizes project work conducted in FY 1994 under the ISR IP in three major areas: treatment (bioremediation), treatment (physical/chemical), and containment technologies. Buried waste, contaminated soils and groundwater, and containerized waste are all candidates for in situ remediation. Contaminants include radioactive waste, volatile and nonvolatile organics, heavy metals, nitrates, and explosive materials.

  20. Features and applications of the integrated composites analyzer (ICAN) code

    Science.gov (United States)

    Ginty, Carol A.

    1988-01-01

    The thermal behavior of composite spacecraft antenna reflectors was investigated with the Integrated Composites Analyzer (ICAN) computer code. Parametric studies were conducted on the face sheets and honeycomb core which constitute the sandwich-type structures. Selected thermal and mechanical properties of the composite faces and sandwich structures are presented graphically as functions of varying fiber volume ratio, laminate configuration, fabrication factors, and environmental conditions.

  1. Features of integrated professional training for physically disabled ...

    African Journals Online (AJOL)

    2009-07-11

    Jul 11, 2009 ... individuals. Rev Med Switzerland Romande 2001;121:453–6. 14. Roy CW, Hunter J, Arthur Y, Prescott RJ. Is handicap affected by hospital- based rehabilitation programs? Scand J Rehabil Med 1992;24:105–12. 15. Karp N, Bradley V. Family support. Child Today 1991;20:28–31. 16. Alberte Castineiras JR ...

  2. Software features and applications in process design, integration and operation

    Energy Technology Data Exchange (ETDEWEB)

    Dhole, V. [Aspen Tech Limited, Warrington (United Kingdom)

    1999-02-01

    Process engineering technologies and tools have evolved rapidly over the last twenty years. Process simulation/modeling, advanced process control, on-line optimisation, production planning and supply chain management are some of the examples of technologies that have rapidly matured from early commercial prototypes and concepts to established tools with significant impact on profitability of process industry today. Process Synthesis or Process Integration (PI) in comparison is yet to create its impact and still remains largely in the domain of few expert users. One of the key reasons as to why PI has not taken off is because the PI tools have not become integral components of the standard process engineering environments. On the last 15 years AspenTech has grown from a small process simulation tool provider to a large multinational company providing a complete suite of process engineering technologies and services covering process design, operation, planning and supply chain management. Throughout this period, AspenTech has acquired experience in rapidly evolving technologies from their early prototype stage to mature products and services. The paper outlines AspenTech`s strategy of integrating PI with other more established process design and operational improvement technologies. The paper illustrates the key elements of AspenTech`s strategy via examples of software development initiatives and services projects. The paper also outlines AspenTech`s future vision of the role of PI in process engineering. (au)

  3. Integrated Data Analysis (IDCA) Program - PETN Class 4 Standard

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Shelley, Timothy J. [Air Force Research Lab. (AFRL), Tyndall AFB, FL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Phillips, Jason J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2012-08-01

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of PETN Class 4. The PETN was found to have: 1) an impact sensitivity (DH50) range of 6 to 12 cm, 2) a BAM friction sensitivity (F50) range 7 to 11 kg, TIL (0/10) of 3.7 to 7.2 kg, 3) a ABL friction sensitivity threshold of 5 or less psig at 8 fps, 4) an ABL ESD sensitivity threshold of 0.031 to 0.326 j/g, and 5) a thermal sensitivity of an endothermic feature with Tmin = ~ 141 °C, and a exothermic feature with a Tmax = ~205°C.

  4. Features of Functioning the Integrated Building Thermal Model

    Directory of Open Access Journals (Sweden)

    Morozov Maxim N.

    2017-01-01

    Full Text Available A model of the building heating system, consisting of energy source, a distributed automatic control system, elements of individual heating unit and heating system is designed. Application Simulink of mathematical package Matlab is selected as a platform for the model. There are the specialized application Simscape libraries in aggregate with a wide range of Matlab mathematical tools allow to apply the “acausal” modeling concept. Implementation the “physical” representation of the object model gave improving the accuracy of the models. Principle of operation and features of the functioning of the thermal model is described. The investigations of building cooling dynamics were carried out.

  5. An integrated user-oriented laboratory for verification of digital flight control systems: Features and capabilities

    Science.gov (United States)

    Defeo, P.; Doane, D.; Saito, J.

    1982-01-01

    A Digital Flight Control Systems Verification Laboratory (DFCSVL) has been established at NASA Ames Research Center. This report describes the major elements of the laboratory, the research activities that can be supported in the area of verification and validation of digital flight control systems (DFCS), and the operating scenarios within which these activities can be carried out. The DFCSVL consists of a palletized dual-dual flight-control system linked to a dedicated PDP-11/60 processor. Major software support programs are hosted in a remotely located UNIVAC 1100 accessible from the PDP-11/60 through a modem link. Important features of the DFCSVL include extensive hardware and software fault insertion capabilities, a real-time closed loop environment to exercise the DFCS, an integrated set of software verification tools, and a user-oriented interface to all the resources and capabilities.

  6. Integrated Safety Program for the Nuclear Electric Propulsion Space Test Program

    Science.gov (United States)

    Marshall, Albert C.; Mehlman, William F.; Kompanietz, G.

    1994-07-01

    The Nuclear Electric Propulsion Space Test Program (NEPSTP) is sponsored by the Ballistic Missile Defense Office (BMDO) to demonstrate and evaluate the Russian-built TOPAZ II nuclear reactor as a power source for an electric propulsion system in space. From its inception, safety has been a central feature of the NEPSTP program. This paper addresses the work done to define the safety organizational relationships, responsibilities, management, engineering requirements, and documentation to assure an integrated safety program that coordinates the various safety activities in Mission Safety, Range Safety and Nuclear Safety. Because the United States has not launched a nuclear reactor since 1965, much of the focus of the safety program has been directed toward the unique safety considerations of using a nuclear reactor in space. Our preliminary findings indicate that the safe use of the TOPAZ II for the NEPSTP space mission is feasible.

  7. An integrated scheduling and program management system

    Science.gov (United States)

    Porter, D.; Gibson, J. D.; Williams, G. G.

    2012-09-01

    An integrated scheduling and program management system is being developed for the MMT Observatory (MMTO), Arizona, USA. A systems engineering approach is used to combine existing and new relational databases, spreadsheets, file storage systems, and web-based user interfaces into a single unified system. An overview of software design, data management, user interfaces, and techniques for performance assessment is presented. Goals of this system include streamlined data management and an optimized user experience. The MMTO has over a dozen different telescope configurations, including three secondary mirrors and a wide range of observing instruments. Scheduling is complex for the varying telescope configurations, limited available observing time, and appropriate astronomic conditions (e.g., lunar phase) for each science project. Scheduled telescope configurations can be used to perform safety checks of actual configuration during telescope operations. Programmatic information is automatically input into nightly telescope operator (TO) logs by the system. The TO's provide additional information into the system on telescope usage, observing conditions (e.g., weather conditions), and observatory closure (e.g., from instrument malfunction or inclement weather). All of this information is synthesized to assess telescope and observatory performance. Web interfaces to the system can be used by observers to submit information, such as travel plans, instrumentation requirements, and observing catalogs. A service request (SR) (i.e., trouble report) system has also been developed for tracking operational issues. The specific needs of the MMTO have been met through in-house software development of this integrated scheduling and program management system.

  8. FEATnotator: A tool for integrated annotation of sequence features and variation, facilitating interpretation in genomics experiments.

    Science.gov (United States)

    Podicheti, Ram; Mockaitis, Keithanne

    2015-06-01

    As approaches are sought for more efficient and democratized uses of non-model and expanded model genomics references, ease of integration of genomic feature datasets is especially desirable in multidisciplinary research communities. Valuable conclusions are often missed or slowed when researchers refer experimental results to a single reference sequence that lacks integrated pan-genomic and multi-experiment data in accessible formats. Association of genomic positional information, such as results from an expansive variety of next-generation sequencing experiments, with annotated reference features such as genes or predicted protein binding sites, provides the context essential for conclusions and ongoing research. When the experimental system includes polymorphic genomic inputs, rapid calculation of gene structural and protein translational effects of sequence variation from the reference can be invaluable. Here we present FEATnotator, a lightweight, fast and easy to use open source software program that integrates and reports overlap and proximity in genomic information from any user-defined datasets including those from next generation sequencing applications. We illustrate use of the tool by summarizing whole genome sequence variation of a widely used natural isolate of Arabidopsis thaliana in the context of gene models of the reference accession. Previous discovery of a protein coding deletion influencing root development is replicated rapidly. Appropriate even in investigations of a single gene or genic regions such as QTL, comprehensive reports provided by FEATnotator better prepare researchers for interpretation of their experimental results. The tool is available for download at http://featnotator.sourceforge.net. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Variability in Integrated Cardiothoracic Training Program Curriculum.

    Science.gov (United States)

    Stephens, Elizabeth H; Walters, Dustin M; Eilers, Amanda L; Tchantchaleishvili, Vakhtang; Goldstone, Andrew B; Gillaspie, Erin A; Fiedler, Amy; LaPar, Damien J

    2017-06-01

    Development of curricula that appropriately progress a resident from medical school graduate to fully trained cardiothoracic surgeon is a key challenge for integrated cardiothoracic training programs. This study examined variability and perceived challenges in integrated curricula. Responses to the 2016 TSDA/TSRA survey that accompanies the annual in-training exam taken by current cardiothoracic surgery residents were analyzed. Standard statistical methods were utilized to examine trends in participant responses. General surgery experience decreased with post-graduate year, whereas cardiac operative experience increased. Rotations in a wide variety of adjunct fields were common. The majority (87%) of respondents reported had dedicated cardiothoracic intensive care unit (ICU) rotations, and surgical ICU and cardiac care unit rotations were less common (68% and 42%, respectively). The most common surgical subspecialty rotations were vascular (94%) and acute care surgery (88%), with a wide range of clinical exposure (ie, 3-44 weeks for vascular). Importantly, 52% felt competition with general surgery residents for experience and 22.5% of general surgery rotations were at hospitals without general surgery residents. Perceived challenges included optimization of rotations (78%), faculty allowing residents to perform case components (60%), faculty teaching in the operating room (29%), and improving surgical experience on general surgery rotations (19%). Significant variation exists in integrated cardiothoracic surgery curricula. Optimization of rotations, access to surgical experience, and integration with general surgery appear to be the most significant perceived challenges. These data suggest that optimization of early clinical and surgical experience within institutions could improve trainee preparedness for senior cardiothoracic surgery training. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  10. A 3D printed fluidic device that enables integrated features.

    Science.gov (United States)

    Anderson, Kari B; Lockwood, Sarah Y; Martin, R Scott; Spence, Dana M

    2013-06-18

    Fluidic devices fabricated using conventional soft lithography are well suited as prototyping methods. Three-dimensional (3D) printing, commonly used for producing design prototypes in industry, allows for one step production of devices. 3D printers build a device layer by layer based on 3D computer models. Here, a reusable, high throughput, 3D printed fluidic device was created that enables flow and incorporates a membrane above a channel in order to study drug transport and affect cells. The device contains 8 parallel channels, 3 mm wide by 1.5 mm deep, connected to a syringe pump through standard, threaded fittings. The device was also printed to allow integration with commercially available membrane inserts whose bottoms are constructed of a porous polycarbonate membrane; this insert enables molecular transport to occur from the channel to above the well. When concentrations of various antibiotics (levofloxacin and linezolid) are pumped through the channels, approximately 18-21% of the drug migrates through the porous membrane, providing evidence that this device will be useful for studies where drug effects on cells are investigated. Finally, we show that mammalian cells cultured on this membrane can be affected by reagents flowing through the channels. Specifically, saponin was used to compromise cell membranes, and a fluorescent label was used to monitor the extent, resulting in a 4-fold increase in fluorescence for saponin treated cells.

  11. Integrative and distinctive coding of visual and conceptual object features in the ventral visual stream.

    Science.gov (United States)

    Martin, Chris B; Douglas, Danielle; Newsome, Rachel N; Man, Louisa Ly; Barense, Morgan D

    2018-02-02

    A significant body of research in cognitive neuroscience is aimed at understanding how object concepts are represented in the human brain. However, it remains unknown whether and where the visual and abstract conceptual features that define an object concept are integrated. We addressed this issue by comparing the neural pattern similarities among object-evoked fMRI responses with behavior-based models that independently captured the visual and conceptual similarities among these stimuli. Our results revealed evidence for distinctive coding of visual features in lateral occipital cortex, and conceptual features in the temporal pole and parahippocampal cortex. By contrast, we found evidence for integrative coding of visual and conceptual object features in perirhinal cortex. The neuroanatomical specificity of this effect was highlighted by results from a searchlight analysis. Taken together, our findings suggest that perirhinal cortex uniquely supports the representation of fully specified object concepts through the integration of their visual and conceptual features. © 2018, Martin et al.

  12. 20 CFR 404.1503a - Program integrity.

    Science.gov (United States)

    2010-04-01

    ... procedures for reasons bearing on professional competence, professional conduct, or financial integrity; or... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Program integrity. 404.1503a Section 404... INSURANCE (1950- ) Determining Disability and Blindness Determinations § 404.1503a Program integrity. We...

  13. 20 CFR 416.903a - Program integrity.

    Science.gov (United States)

    2010-04-01

    ... for reasons bearing on professional competence, professional conduct, or financial integrity; or who... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Program integrity. 416.903a Section 416.903a... DISABLED Determining Disability and Blindness Determinations § 416.903a Program integrity. We will not use...

  14. Inside Out: Program Integrity and Effectiveness of the Cognitive-Behavioural Program EQUIP for Incarcerated Youth

    NARCIS (Netherlands)

    Helmond, P.E.

    2013-01-01

    In correctional facilities intervention programs are used to reduce behavioral problems and recidivism. Intervention programs can be effective when they contain effective ingredients and are implemented with high levels of program integrity. Program integrity is the degree to which programs are

  15. Integrating New Technologies and Existing Tools to Promote Programming Learning

    Directory of Open Access Journals (Sweden)

    Álvaro Santos

    2010-04-01

    Full Text Available In recent years, many tools have been proposed to reduce programming learning difficulties felt by many students. Our group has contributed to this effort through the development of several tools, such as VIP, SICAS, OOP-Anim, SICAS-COL and H-SICAS. Even though we had some positive results, the utilization of these tools doesn’t seem to significantly reduce weaker student’s difficulties. These students need stronger support to motivate them to get engaged in learning activities, inside and outside classroom. Nowadays, many technologies are available to create contexts that may help to accomplish this goal. We consider that a promising path goes through the integration of solutions. In this paper we analyze the features, strengths and weaknesses of the tools developed by our group. Based on these considerations we present a new environment, integrating different types of pedagogical approaches, resources, tools and technologies for programming learning support. With this environment, currently under development, it will be possible to review contents and lessons, based on video and screen captures. The support for collaborative tasks is another key point to improve and stimulate different models of teamwork. The platform will also allow the creation of various alternative models (learning objects for the same subject, enabling personalized learning paths adapted to each student knowledge level, needs and preferential learning styles. The learning sequences will work as a study organizer, following a suitable taxonomy, according to student’s cognitive skills. Although the main goal of this environment is to support students with more difficulties, it will provide a set of resources supporting the learning of more advanced topics. Software engineering techniques and representations, object orientation and event programming are features that will be available in order to promote the learning progress of students.

  16. Design Reference Missions (DRM): Integrated ODM 'Air-Taxi' Mission Features

    Science.gov (United States)

    Kloesel, Kurt; Starr, Ginn; Saltzman, John A.

    2017-01-01

    Design Reference Missions (DRM): Integrated ODM Air-Taxi Mission Features, Hybrid Electric Integrated System Testbed (HEIST) flight control. Structural Health, Energy Storage, Electric Components, Loss of Control, Degraded Systems, System Health, Real-Time IO Operator Geo-Fencing, Regional Noise Abatement and Trusted Autonomy Inter-operability.

  17. Impact of integrated programs on general surgery operative volume.

    Science.gov (United States)

    Jensen, Amanda R; Nickel, Brianne L; Dolejs, Scott C; Canal, David F; Torbeck, Laura; Choi, Jennifer N

    2017-03-01

    Integrated residencies are now commonplace, co-existing with categorical general surgery residencies. The purpose of this study was to define the impact of integrated programs on categorical general surgery operative volume. Case logs from categorical general, integrated plastics, vascular, and thoracic surgery residents from a single institution from 2008 to 2016 were collected and analyzed. Integrated residents have increased the number of cases they perform that would have previously been general surgery resident cases from 11 in 2009-2010 to 1392 in 2015-2016. Despite this, there was no detrimental effect on total major cases of graduating chief residents. Multiple integrated programs can co-exist with a general surgery program through careful collaboration and thoughtful consideration to longitudinal needs of individual trainees. As additional programs continue to be created, both integrated and categorical program directors must continue to collaborate to insure the integrity of training for all residents. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. An Accurate Integral Method for Vibration Signal Based on Feature Information Extraction

    Directory of Open Access Journals (Sweden)

    Yong Zhu

    2015-01-01

    Full Text Available After summarizing the advantages and disadvantages of current integral methods, a novel vibration signal integral method based on feature information extraction was proposed. This method took full advantage of the self-adaptive filter characteristic and waveform correction feature of ensemble empirical mode decomposition in dealing with nonlinear and nonstationary signals. This research merged the superiorities of kurtosis, mean square error, energy, and singular value decomposition on signal feature extraction. The values of the four indexes aforementioned were combined into a feature vector. Then, the connotative characteristic components in vibration signal were accurately extracted by Euclidean distance search, and the desired integral signals were precisely reconstructed. With this method, the interference problem of invalid signal such as trend item and noise which plague traditional methods is commendably solved. The great cumulative error from the traditional time-domain integral is effectively overcome. Moreover, the large low-frequency error from the traditional frequency-domain integral is successfully avoided. Comparing with the traditional integral methods, this method is outstanding at removing noise and retaining useful feature information and shows higher accuracy and superiority.

  19. Critical Care Organizations: Building and Integrating Academic Programs.

    Science.gov (United States)

    Moore, Jason E; Oropello, John M; Stoltzfus, Daniel; Masur, Henry; Coopersmith, Craig M; Nates, Joseph; Doig, Christopher; Christman, John; Hite, R Duncan; Angus, Derek C; Pastores, Stephen M; Kvetan, Vladimir

    2017-12-16

    Academic medical centers in North America are expanding their missions from the traditional triad of patient care, research, and education to include the broader issue of healthcare delivery improvement. In recent years, integrated Critical Care Organizations have developed within academic centers to better meet the challenges of this broadening mission. The goal of this article was to provide interested administrators and intensivists with the proper resources, lines of communication, and organizational approach to accomplish integration and Critical Care Organization formation effectively. The Academic Critical Care Organization Building section workgroup of the taskforce established regular monthly conference calls to reach consensus on the development of a toolkit utilizing methods proven to advance the development of their own academic Critical Care Organizations. Relevant medical literature was reviewed by literature search. Materials from federal agencies and other national organizations were accessed through the Internet. The Society of Critical Care Medicine convened a taskforce entitled "Academic Leaders in Critical Care Medicine" on February 22, 2016 at the 45th Critical Care Congress using the expertise of successful leaders of advanced governance Critical Care Organizations in North America to develop a toolkit for advancing Critical Care Organizations. Key elements of an academic Critical Care Organization are outlined. The vital missions of multidisciplinary patient care, safety, and quality are linked to the research, education, and professional development missions that enhance the value of such organizations. Core features, benefits, barriers, and recommendations for integration of academic programs within Critical Care Organizations are described. Selected readings and resources to successfully implement the recommendations are provided. Communication with medical school and hospital leadership is discussed. We present the rationale for critical

  20. A multiaspect program integrity assessment of the cognitive-behavioral program EQUIP for incarcerated offenders

    NARCIS (Netherlands)

    Helmond, P.; Overbeek, G.; Brugman, D.

    2014-01-01

    Studies on the effectiveness of correctional treatment have widely failed to assess program integrity. This study examined the program integrity of EQUIP in 34 treatment groups of incarcerated offenders, using a new multiaspect program integrity instrument (MIPIE). The first aim of our study was to

  1. In Situ Remediation Integrated Program: Technology summary

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The In Situ Remediation Integrated Program (ISR IP) was instituted out of recognition that in situ remediation could fulfill three important criteria: significant cost reduction of cleanup by eliminating or minimizing excavation, transportation, and disposal of wastes; reduced health impacts on workers and the public by minimizing exposure to wastes during excavation and processing; and remediation of inaccessible sites, including: deep subsurfaces, in, under, and around buildings. Buried waste, contaminated soils and groundwater, and containerized wastes are all candidates for in situ remediation. Contaminants include radioactive wastes, volatile and non-volatile organics, heavy metals, nitrates, and explosive materials. The ISR IP intends to facilitate development of in situ remediation technologies for hazardous, radioactive, and mixed wastes in soils, groundwater, and storage tanks. Near-term focus is on containment of the wastes, with treatment receiving greater effort in future years. ISR IP is an applied research and development program broadly addressing known DOE environmental restoration needs. Analysis of a sample of 334 representative sites by the Office of Environmental Restoration has shown how many sites are amenable to in situ remediation: containment--243 sites; manipulation--244 sites; bioremediation--154 sites; and physical/chemical methods--236 sites. This needs assessment is focused on near-term restoration problems (FY93--FY99). Many other remediations will be required in the next century. The major focus of the ISR EP is on the long term development of permanent solutions to these problems. Current needs for interim actions to protect human health and the environment are also being addressed.

  2. Integrated rural development programs: a skeptical perspective.

    Science.gov (United States)

    Ruttan, V W

    1975-11-01

    In examining integrated rural development programs the question that arises is why is it possible to identify several relatively successful small-scale or pilot rural development projects yet so difficult to find examples of successful rural development programs. 3 bodies of literature offer some insight into the morphology of rural development projects, programs, and processes: the urban-industrial impact hypothesis; the theory of induced technical change; and the new models of institutional change that deal with institution building and the economics of bureaucratic behavior. The urban-industrial impact hypothesis helps in the clarification of the relationships between the development of rural areas and the development of the total society of which rural areas are a part. It is useful in understanding the spatial dimensions of rural development where rural development efforts are likely to be most successful. Formulation of the hypothesis generated a series of empirical studies designed to test its validity. The effect of these studies has been the development of a rural development model in which the rural community is linked to the urban-industrial economy through a series of market relationships. Both the urban economy's rate of growth and the efficiency of the intersector product and factor markets place significant constraints on the possibilities of rural area development. It is not possible to isolate development processes in the contemporary rural community in a developing society from development processes in the larger society. The induced technical change theory provides a guide as to what must be done to gain access to efficient sources of economic growth, the new resources and incomes that are necessary to sustain rural development. Design of a successful rural development strategy involves a combination of technical and institutional change. The ability of rural areas to respond to the opportunities for economic growth generated by local urban

  3. Particular features of development and realizations of purposeful complex programs in Ukraine

    Directory of Open Access Journals (Sweden)

    О.В. Самков

    2004-04-01

    Full Text Available  Features of development and realization of aviation purposeful complex programs in Ukraine are examined. The necessity of metrology securing of aviation programs as well as decision making process in the logistics system during complex programs development and realization. Examples from the modernization programs of aviation are analyzed.

  4. Feature Program: Project N.I.C.E.

    Science.gov (United States)

    Education Journal of the Institute for the Development of Indian Law, 1973

    1973-01-01

    The Northern Indian California Education Project, established in 1971, has pilot programs in 6 schools which reach out to 24 additional schools. The article lists project goals, the implementation of these goals, accomplishments, and available materials. (KM)

  5. Remodularizing Java Programs for Improved Locality of Feature Implementations in Source Code

    DEFF Research Database (Denmark)

    Olszak, Andrzej; Jørgensen, Bo Nørregaard

    2011-01-01

    Explicit traceability between features and source code is known to help programmers to understand and modify programs during maintenance tasks. However, the complex relations between features and their implementations are not evident from the source code of object-oriented Java programs. Conseque...

  6. Features of using multimedia technologies at lecturing programming

    Directory of Open Access Journals (Sweden)

    G. S. Ivanova

    2014-01-01

    Full Text Available The subject of study of this paper is multimedia capabilities, which are used for lectures on programming for undergraduate students to learn Computer Science and Engineering.The objective is to analyze the factors affecting the efficiency of lectures on programming, readable using multimedia, identifying the advantages and disadvantages of using presentations and process of creating and debugging programs in software environments demonstration, and to make recommendations on the use of illustrative material aimed at improving student's handout with the knowledge readable material.Scientific novelty of the material is to identify and analyze the factors influencing the effectiveness of teaching programming using multimedia as well as to make recommendations on the creation of illustrative material in the form of lecture presentations, analyse the negative side effects of presentations and opportunities to address them.It is stated that even at the initial stage of teaching in programming the amount of learning material and associated details in their records to which student's attention should be drawn, commensurate with the restrictions of psycho physiological capabilities defined for modern undergraduate students to remember and learn. The conclusion about expediency to improve lectures efficiency through the use of multimedia equipment capabilities is made.The types of illustrative material used in lectures on programming are listed and named, examples of illustrative material for presentation slides are analyzed. The positive results of the process of program creating, debugging and running directly in the programming environment during the lecture are underlined .As the merits of the multimedia-based lectures are marked a significant reduction of time to be required for material presentation ( from 10 to 30 % and the structured and with no errors in the program texts of lectures available for students. Negative effects of the multimedia

  7. Tibetan Information Extraction Technology Integrated with Event Feature and Semantic Role Labelling

    Directory of Open Access Journals (Sweden)

    Wan Fucheng

    2017-01-01

    Full Text Available we integrate with semantic information which is based on syntactic analysis for extracting the Tibetan information. For Tibetan language information extraction, through experiments analyzed, syntactic analysis model which is integrated with information of semantics, as well as the evaluation of program can be used in Tibetan language information extraction task successfully.

  8. Integration of Information Sources of Varying Weights: The Effect of Display Features and Attention Cueing

    Science.gov (United States)

    1999-01-01

    arriving cue ( primacy ), sometimes in favor of the last ( recency ), and sometimes in favor of both, with cues arriving in the middle of a sequence...INFORMATION SOURCES OF VARYING WEIGHTS: THE EFFECT OF DISPLAY FEATURES AND ATTENTION CUEING Christopher D. Wickens, Heather L. Pringle, and James Merlo...SUBTITLE Integration of Information Sources of Varying Weights: The Effect of Display Features and Attention Cueing 5a. CONTRACT NUMBER 5b. GRANT

  9. 42 CFR 460.68 - Program integrity.

    Science.gov (United States)

    2010-10-01

    ... convicted of physical, sexual, drug, or alcohol abuse. (b) Direct or indirect interest in contracts. The...) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE...

  10. Mathematica as program support in the integral calculations

    OpenAIRE

    Zlatanovska, Biljana; Stojanova, Aleksandra; Kocaleva, Mirjana; Stojkovic, Natasa; Krstev, Aleksandar

    2016-01-01

    In this paper, we give а connection between the mathematical notions and using the computer as educational support at university level. Specifically, mathematical notions used in integral calculations will be explained with help of computer program. The notions, indefinite and definite integral, their calculations and their applications can be easily understand using the computer programs for their presentation. Images obtained with computer programs allows the students to better understand a...

  11. An Integrated Skills Approach Using Feature Movies in EFL at Tertiary Level

    Science.gov (United States)

    Tuncay, Hidayet

    2014-01-01

    This paper presents the results of a case study based on an integrated skills approach using feature movies (DVDs) in EFL syllabi at the tertiary level. 100 students took part in the study and the data was collected through a three - section survey questionnaire: demographic items, 18 likert scale questions and an open-ended question. The data…

  12. Integration of School Features into Taiwanese Elementary School New English Curriculum

    Science.gov (United States)

    Chien, Chin-Wen

    2014-01-01

    Elementary school English activation curriculum, an additional two culture classes, has been implemented only in New Taipei City in Taiwan starting from 2010, so only a few studies focus on it. This is a case study of an English teacher's integration of a school's features into the activation curriculum in a rural elementary school. This study…

  13. Using Feature Films to Integrate Themes and Concepts in the Basic Course.

    Science.gov (United States)

    Smitter, Roger

    The typical textbook for the basic course fails to integrate the broad range of topics it introduces to the new student of communication. One way of addressing this problem would be to use feature films in the course, such as "Wall Street,""True Colors,""Other People's Money,""Milagro Beanfield War," and…

  14. Treatment Integrity of Elaborated Semantic Feature Analysis Aphasia Therapy Delivered in Individual and Group Settings

    Science.gov (United States)

    Kladouchou, Vasiliki; Papathanasiou, Ilias; Efstratiadou, Eva A.; Christaki, Vasiliki; Hilari, Katerina

    2017-01-01

    Background & Aims: This study ran within the framework of the Thales Aphasia Project that investigated the efficacy of elaborated semantic feature analysis (ESFA). We evaluated the treatment integrity (TI) of ESFA, i.e., the degree to which therapists implemented treatment as intended by the treatment protocol, in two different formats:…

  15. One-Step Fabrication of Microchannels with Integrated Three Dimensional Features by Hot Intrusion Embossing

    Directory of Open Access Journals (Sweden)

    Mike Debono

    2016-11-01

    Full Text Available We build on the concept of hot intrusion embossing to develop a one-step fabrication method for thermoplastic microfluidic channels containing integrated three-dimensional features. This was accomplished with simple, rapid-to-fabricate imprint templates containing microcavities that locally control the intrusion of heated thermoplastic based on their cross-sectional geometries. The use of circular, rectangular and triangular cavity geometries was demonstrated for the purposes of forming posts, multi-focal length microlense arrays, walls, steps, tapered features and three-dimensional serpentine microchannels. Process variables, such as temperature and pressure, controlled feature dimensions without affecting the overall microchannel geometry. The approach was demonstrated for polycarbonate, cycloolefin copolymer and polystyrene, but in principle is applicable to any thermoplastic. The approach is a step forward towards rapid fabrication of complex, robust, microfluidic platforms with integrated multi-functional elements.

  16. One-Step Fabrication of Microchannels with Integrated Three Dimensional Features by Hot Intrusion Embossing.

    Science.gov (United States)

    Debono, Mike; Voicu, Dan; Pousti, Mohammad; Safdar, Muhammad; Young, Robert; Kumacheva, Eugenia; Greener, Jesse

    2016-11-29

    We build on the concept of hot intrusion embossing to develop a one-step fabrication method for thermoplastic microfluidic channels containing integrated three-dimensional features. This was accomplished with simple, rapid-to-fabricate imprint templates containing microcavities that locally control the intrusion of heated thermoplastic based on their cross-sectional geometries. The use of circular, rectangular and triangular cavity geometries was demonstrated for the purposes of forming posts, multi-focal length microlense arrays, walls, steps, tapered features and three-dimensional serpentine microchannels. Process variables, such as temperature and pressure, controlled feature dimensions without affecting the overall microchannel geometry. The approach was demonstrated for polycarbonate, cycloolefin copolymer and polystyrene, but in principle is applicable to any thermoplastic. The approach is a step forward towards rapid fabrication of complex, robust, microfluidic platforms with integrated multi-functional elements.

  17. 75 FR 66831 - Program Integrity Issues

    Science.gov (United States)

    2010-10-29

    ... Education (TEACH) Grant Program in part 686, the Federal Pell Grant Program, and the Academic... on satisfactory academic progress, Marty Guthrie or Marianna Deeken. Telephone: (202) 219-7031 or via... (FRS), toll free, at 1-800-877-8339. Individuals with disabilities can obtain this document in an...

  18. 76 FR 20534 - Program Integrity Issues

    Science.gov (United States)

    2011-04-13

    ... the Federal Register and the Code of Federal Regulations is available via the Federal Digital System... educational programs or those that provide marketing, advertising, recruiting, or admissions services. We have... the institution to provide services, such as food service, other than educational programs, marketing...

  19. Integrating Robot Task Planning into Off-Line Programming Systems

    DEFF Research Database (Denmark)

    Sun, Hongyan; Kroszynski, Uri

    1988-01-01

    The addition of robot task planning in off-line programming systems aims at improving the capability of current state-of-the-art commercially available off-line programming systems, by integrating modeling, task planning, programming and simulation together under one platform. This article proposes...... a system architecture for integrated robot task planning. It identifies and describes the components considered necessary for implementation. The focus is on functionality of these elements as well as on the information flow. A pilot implementation of such an integrated system architecture for a robot...

  20. Enhancing Usefulness of Declarative Programming Frameworks through Complete Integration

    OpenAIRE

    Falkman, Goran; Torgersson, Olof

    2002-01-01

    The Gisela framework for declarative programming was developed with the specific aim of providing a tool that would be useful for knowledge representation and reasoning within real-world applications. To achieve this, a complete integration into an object-oriented application development environment was used. The framework and methodology developed provide two alternative application programming interfaces (APIs): Programming using objects or programming using a traditional equational declara...

  1. Articulation Therapy Using Distinctive Feature Analysis to Structure the Training Program: Two Case Studies.

    Science.gov (United States)

    Ruder, Kenneth F.; Bunce, Betty H.

    1981-01-01

    Two case reports of 4 and 5 year old children describe the rationale and procedures for structuring an articulation therapy program on the basis of distinctive feature analysis of the child's articulation problems. (Author/DB)

  2. An integration of minimum local feature representation methods to recognize large variation of foods

    Science.gov (United States)

    Razali, Mohd Norhisham bin; Manshor, Noridayu; Halin, Alfian Abdul; Mustapha, Norwati; Yaakob, Razali

    2017-10-01

    Local invariant features have shown to be successful in describing object appearances for image classification tasks. Such features are robust towards occlusion and clutter and are also invariant against scale and orientation changes. This makes them suitable for classification tasks with little inter-class similarity and large intra-class difference. In this paper, we propose an integrated representation of the Speeded-Up Robust Feature (SURF) and Scale Invariant Feature Transform (SIFT) descriptors, using late fusion strategy. The proposed representation is used for food recognition from a dataset of food images with complex appearance variations. The Bag of Features (BOF) approach is employed to enhance the discriminative ability of the local features. Firstly, the individual local features are extracted to construct two kinds of visual vocabularies, representing SURF and SIFT. The visual vocabularies are then concatenated and fed into a Linear Support Vector Machine (SVM) to classify the respective food categories. Experimental results demonstrate impressive overall recognition at 82.38% classification accuracy based on the challenging UEC-Food100 dataset.

  3. Diffusion of Courses with World Wide Web Features: Perceptions of Journalism and Mass Communication Program Administrators.

    Science.gov (United States)

    Sutherland, Patrick J.

    2003-01-01

    Examines perceptions of top administrators concerning courses with Web features at Association of Schools of Journalism and Mass Communication (ASJMC) programs. Studies the imperatives and pressures to implement courses with Web features as well as resistances to implementation. Suggests that administrators perceive an extensive set of needs and…

  4. 75 FR 43615 - Program Integrity: Gainful Employment

    Science.gov (United States)

    2010-07-26

    ... would develop proposed regulations governing foreign institutions, including the implementation of the... foreign institutions. A second committee would develop proposed regulations to improve integrity in the... stigma of default can send an unfortunate message to others--that seeking an education can have...

  5. Program Collaboration and Service Integration At-a-Glance

    Centers for Disease Control (CDC) Podcasts

    2010-09-15

    Dr. Kevin A. Fenton, Director of CDC's National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, discusses program collaboration and service integration, a strategy that promotes better collaboration between public health programs and supports appropriate service integration at the point-of-care.  Created: 9/15/2010 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention.   Date Released: 9/15/2010.

  6. COHERENT INTEGRATION OF STRATEGIC PROGRAM MANAGEMENT SUBSYSTEMS OF CITY DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Дмитро Заурійович БЕРУЛАВА

    2015-06-01

    Full Text Available Considered by the scientific task of developing and implementing an effective strategic development program of the modern city. Proposes a model of coherent integration of management program subsystem on the stages of its development and implementation. Identified the element subsystems that must be synchronized for the coherent integration. Was concluded about the effectiveness of this approach, outlined the direction of its development.

  7. A stochastic-programming approach to integrated asset and liability ...

    African Journals Online (AJOL)

    This increase in complexity has provided an impetus for the investigation into integrated asset- and liability-management frameworks that could realistically address dynamic portfolio allocation in a risk-controlled way. In this paper the authors propose a multi-stage dynamic stochastic-programming model for the integrated ...

  8. Affective Aspects of an Age-Integrated Water Exercise Program.

    Science.gov (United States)

    Weiss, Caroline R.; Jamieson, Nancy B.

    1987-01-01

    Surveyed 88 female participants of community-based age-integrated water exercise program designed to enhance comfort and social interaction. Affective measures and observation of membership as a support group elicited few differences by age. Members endorsed having age integration in classes and there was little indication that subgroups of…

  9. What's New in Software? Integrated Computer Programs and Daily Living.

    Science.gov (United States)

    Hedley, Carolyn N.

    1989-01-01

    Various kinds of electronic information media can now be integrated to plan educational programs, through use of computer videodiscs, hypercards, and hypertexts. Discussed are the components of integrative technology, including audio technology, video technology, and electronic text and graphics, and possibilities for interfacing the various…

  10. Integrating Ethics in Community Colleges' Accounting Programs.

    Science.gov (United States)

    Clarke, Clifton

    1990-01-01

    Argues that two-year college business programs need to provide moral guidance and leadership to students to help stem the proliferation of fraudulent and questionable financial reporting practices. Reviews amoral and moral unity theories of business ethics. Discusses barriers to ethical instruction in business curricula, and ways to overcome them.…

  11. 78 FR 17598 - Program Integrity Issues

    Science.gov (United States)

    2013-03-22

    ... Education Act of 1965, as amended (HEA) (October 29, 2010, final regulations). This document revises the...), toll free, at 1-800-877-8339. Individuals with disabilities can obtain this document in an accessible..., the Federal Pell Grant Program, and the Academic Competitiveness Grant (AGC) and National Science and...

  12. Integrating Linear Programming and Analytical Hierarchical ...

    African Journals Online (AJOL)

    A comprehensive Linear Programming model established, including 106 variables and 43 ecological-socio-economic constraints. Land capability and suitability evaluation accomplished using ecological factors and Comparative Advantages of the uses and the factors, respectively. Analytical Hierarchical Process followed ...

  13. Approaches to Work-Integrated Learning and Engaging Industry in Vocational ICT Courses: Evaluation of an Australian Pilot Program

    Science.gov (United States)

    Armatas, Christine; Papadopoulos, Theo

    2013-01-01

    Evaluation of a government-sponsored program for promoting work-integrated learning (WIL) in information communication technology (ICT) courses offered to vocational education students is discussed in this paper. The program provided the opportunity to incorporate WIL in the curriculum which had not previously been a feature of these ICT courses.…

  14. Treatment integrity of elaborated semantic feature analysis aphasia therapydelivered in individual and group settings

    OpenAIRE

    Kladouchou, V.; Papathanasiou, I.; Efstratiadou, E. A.; Christaki, V.; Hilari, K.

    2017-01-01

    Background & Aims\\ud \\ud This study ran within the framework of the Thales Aphasia Project that investigated the efficacy of elaborated semantic feature analysis (ESFA). We evaluated the treatment integrity (TI) of ESFA, i.e., the degree to which therapists implemented treatment as intended by the treatment protocol, in two different formats: individual and group therapy.\\ud \\ud Methods & Procedures\\ud \\ud Based on the ESFA manual, observation of therapy videos and TI literature, we developed...

  15. Evaluation of the Integrated Services Pilot Program from Western Australia

    Science.gov (United States)

    Hancock, Peter; Cooper, Trudi; Bahn, Susanne

    2009-01-01

    Independent evaluation of refugee-focused programs in developed nations is increasingly a mandatory requirement of funding bodies and government agencies. This paper presents an evaluation of the Integrated Services Centre (ISC) Pilot Project that was conducted in Australia in 2007 and early 2008. The purpose of the ISC program was to provide…

  16. Forest productivity: an integrated research and development program

    Science.gov (United States)

    Daniel C. Dey; Thomas R. Crow; Don E. Riemenschneider

    2003-01-01

    In 2000, the North Central Research Station initiated the Forest Productivity Integrated Research Program (North Central Research Station 2001). This program combines the efforts of scientists from across the Station's 13 research work units to examine the current condition of the forests in the North Central Region and their prospects for producing wood and fiber...

  17. Using Research to Design Integrated Education and Training Programs

    Science.gov (United States)

    Pappalardo, Michele; Schaffer, William R.

    2016-01-01

    With the passage of the Workforce Innovation and Opportunity Act (WIOA) of 2014, Northampton Community College began the creation of Integrated Education and Training (IE&T) programs in October 2015. After a needs assessment was conducted with the partners, programs were created to address the needs in the hospitality and healthcare sectors.…

  18. Integrating computer programs for engineering analysis and design

    Science.gov (United States)

    Wilhite, A. W.; Crisp, V. K.; Johnson, S. C.

    1983-01-01

    The design of a third-generation system for integrating computer programs for engineering and design has been developed for the Aerospace Vehicle Interactive Design (AVID) system. This system consists of an engineering data management system, program interface software, a user interface, and a geometry system. A relational information system (ARIS) was developed specifically for the computer-aided engineering system. It is used for a repository of design data that are communicated between analysis programs, for a dictionary that describes these design data, for a directory that describes the analysis programs, and for other system functions. A method is described for interfacing independent analysis programs into a loosely-coupled design system. This method emphasizes an interactive extension of analysis techniques and manipulation of design data. Also, integrity mechanisms exist to maintain database correctness for multidisciplinary design tasks by an individual or a team of specialists. Finally, a prototype user interface program has been developed to aid in system utilization.

  19. Integration of New Features for Telerobotic Surgery into The Mirosurge System

    Directory of Open Access Journals (Sweden)

    Rainer Konietschke

    2011-01-01

    Full Text Available Minimally invasive robotic surgery has gained wide acceptance recently. Computer-aided features to assist the surgeon during these interventions may help to develop safer, faster, and more accurate procedures. Especially physiological motion compensation of the beating heart and online soft tissue modelling are promising features that were developed recently. This paper presents the integration of these new features into the minimally invasive robotic surgery platform MiroSurge. A central aim of this research platform is to enable evaluation and comparison of new functionalities for minimally invasive robotic surgery. The system structure of MiroSurge is presented as well as the interfaces for the new functionalities. Some details about the modules for motion tracking and for soft tissue simulation are given. Results are shown with an experimental setup that includes a heart motion simulator and dedicated silicone organ models. Both features are integrated seamlessly and work reliably in the chosen setup. The MiroSurge platform thus shows the potential to provide valuable results in evaluating new functionalities for minimally invasive robotic surgery.

  20. 75 FR 66665 - Program Integrity: Gainful Employment-New Programs

    Science.gov (United States)

    2010-10-29

    ... regulations for Institutional Eligibility Under the Higher Education Act of 1965, as amended (HEA), to... recommendations and decisions by Department employees who lack expertise in the labor markets. The commenters... online program, regional or national market needs by, for example, consulting BLS data or State labor...

  1. Wide Area Recovery and Resiliency Program (WARRP) Integrated Program Plan

    Science.gov (United States)

    2011-06-01

    on National Planning Scenarios. 15. SUBJECT TERMS WARRP, Program Management 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18...Agent YELLOW, which is a mixture of the chemical warfare agents Sulfur Mustard and Lewisite, is a liquid with a garlic -like odor. Sulfur mustard

  2. Integrated population-development program performance: the Malaysian Felda experience.

    Science.gov (United States)

    Fong, C O

    1985-01-01

    Program performance of the Malaysian Felda program, an integrated population development program, is examined in this report. It also evaluates the relationship of the performance of this program with its organizational, integrational, and community support factors. Starting in 1956, Felda had, by the end of 1981, developed 308 land schemes covering an area of 1.4 million acres planted predominantly with oil palm (59.4%) and rubber (31.6%). The land schemes have settled a total of 70,600 families or over 400,000 people. The integrated programs existing in the Felda schmes are the focus of analysis for this study. Out of the universe of 308 Felda schemes, 26 schemes were randomly selected for the study. In each scheme, 2 surveys were conducted: first, the staff surveys to gather information on the organizational factors and extent of integration in existence in the scheme and then household surveys to gather information on the extent of community support for the integrated program and the performance of the program. In the case of the performance variables, the information gathered from the household survey was supplemented by the records from the Felda scheme office. In the sample of 26 schemes, a total of 1641 settler households were selected for the household survey and 363 staff were selected for the staff survey. The surveys were conducted in the 1st quarter of 1982. The results indicate that the Felda mode of delivering population and community development services has been very effective. Over 55.2% of the eligible women were found to be practicing family planning (compared to about 35.5% for the national rural average), while over 78.9% of the eligible women utilized postnatal health care facilities. About 1 in 3 of the eligible children in Felda schemes attend kindergarten classes, while over 46.9% of the Felda households are involved in some form of extramural income generating activities. The more integrated the program in a particular community, the more

  3. Features of circular training as a part of strength training program for dancer

    OpenAIRE

    Олександрова [Veronika Aleksandrova], Вероніка Анатоліївна; Шиян [Vladimir Shiyan], Віктор Володимирович

    2013-01-01

    says about the results of the experimental program which has been worked out and theoretically substantiated. The program includes two ways of strength training which are strength and stamina development. The program consists of three weeklong micro cycles (units): first week – drawing unit, second week – strength unit, third week – stamina development unit. Circular trainings were carried out according to individual differences of the dancers. The analysis of the literature about features of...

  4. Successful Bullying Prevention Programs: Influence of Research Design, Implementation Features, and Program Components

    Directory of Open Access Journals (Sweden)

    Bryanna Hahn Fox

    2012-12-01

    Full Text Available Bullying prevention programs have been shown to be generally effective in reducing bullying and victimization. However, the effects are relatively small in randomized experiments and greater in quasi-experimental and age-cohort designs. Programs that are more intensive and of longer duration (for both children and teachers are more effective, as are programs containing more components. Several program components are associated with large effect sizes, including parent training or meetings and teacher training. These results should inform the design and evaluation of anti-bullying programs in the future, and a system ofaccreditation of effective programs.

  5. Using Hierarchical Latent Dirichlet Allocation to Construct Feature Tree for Program Comprehension

    Directory of Open Access Journals (Sweden)

    Xiaobing Sun

    2017-01-01

    Full Text Available Program comprehension is an important task faced by developers during software maintenance. With the increasing complexity of evolving systems, program comprehension becomes more and more difficult. In practice, programmers are accustomed to getting a general view of the features in a software system and then finding the interesting or necessary files to start the understanding process. Given a system, developers may need a general view of the system. The traditional view of a system is shown in a package-class structure which is difficult to understand, especially for large systems. In this article, we focus on understanding the system in both feature view and file structure view. This article proposes an approach to generate a feature tree based on hierarchical Latent Dirichlet Allocation (hLDA, which includes two hierarchies, the feature hierarchy and file structure hierarchy. The feature hierarchy shows the features from abstract level to detailed level, while the file structure hierarchy shows the classes from whole to part. Empirical results show that the feature tree can produce a view for the features and files, and the clustering of classes in the package in our approach is better (in terms of recall than the other clustering approach, that is, hierarchical clustering.

  6. Visual feature integration indicated by pHase-locked frontal-parietal EEG signals.

    Directory of Open Access Journals (Sweden)

    Steven Phillips

    Full Text Available The capacity to integrate multiple sources of information is a prerequisite for complex cognitive ability, such as finding a target uniquely identifiable by the conjunction of two or more features. Recent studies identified greater frontal-parietal synchrony during conjunctive than non-conjunctive (feature search. Whether this difference also reflects greater information integration, rather than just differences in cognitive strategy (e.g., top-down versus bottom-up control of attention, or task difficulty is uncertain. Here, we examine the first possibility by parametrically varying the number of integrated sources from one to three and measuring phase-locking values (PLV of frontal-parietal EEG electrode signals, as indicators of synchrony. Linear regressions, under hierarchical false-discovery rate control, indicated significant positive slopes for number of sources on PLV in the 30-38 Hz, 175-250 ms post-stimulus frequency-time band for pairs in the sagittal plane (i.e., F3-P3, Fz-Pz, F4-P4, after equating conditions for behavioural performance (to exclude effects due to task difficulty. No such effects were observed for pairs in the transverse plane (i.e., F3-F4, C3-C4, P3-P4. These results provide support for the idea that anterior-posterior phase-locking in the lower gamma-band mediates integration of visual information. They also provide a potential window into cognitive development, seen as developing the capacity to integrate more sources of information.

  7. Integrating proven falls prevention interventions into government programs.

    Science.gov (United States)

    Day, Lesley; Donaldson, Alex; Thompson, Catherine; Thomas, Margaret

    2014-04-01

    To identify Department of Health programs with high potential to integrate evidence-based interventions to prevent falls among older people. Broad consultation within the Department followed by structured decision making. This work was informed by an analysis of Victorian hospital separations data and a Cochrane Systematic Review to identify relevant target groups and interventions. Ranking of the integration potential of interventions for a broad range of Department program areas was achieved through a facilitated workshop. A short list of program areas was then developed and scored, using pre-defined criteria, for their match with the interventions. The ranked order of interventions, from most to least suitable for integration, were: multifactorial risk assessment and intervention; multi-component group exercise; medication review; occupational therapy-based home safety; home-based exercise; and first eye cataract surgery. Four of six program areas had a strong match (a score of ≥75% of the maximum score) with one or more of three interventions. Two program areas (Primary Care Partnerships, and Home and Community Care) had strong matches with three interventions (group- and home-based exercise; occupational therapy-based home safety) and were selected as priority areas. The Hospital Admissions Risk Program had strong and good matches respectively with home-based exercise and medication review, and was also selected. Our systematic methods identified Department programs with strong potential for integration of proven falls prevention interventions. Matching departmental programs and evidence-based interventions for integration may lead to more efficient resource allocation for falls prevention in Victoria. © 2014 The Authors. ANZJPH © 2014 Public Health Association of Australia.

  8. The time course of feature integration in plaid patterns revealed by meta- and paracontrast masking.

    Science.gov (United States)

    Bruchmann, Maximilian; Hintze, Philipp; Vorwerk, Johannes

    2012-12-14

    When a plaid object is presented, the visual system decomposes it into its constituting orientation primitives and integrates them at later processing stages. The present study reveals the time course of this process by applying meta- and paracontrast masking to both simple oriented and plaid gratings. With various stimulus onset asynchronies (SOA) between target gratings and surrounding mask annuli, subjects were asked to identify whether targets were simple gratings collinear to the masks, orthogonal to the masks, plaid, or whether no target was presented. The resulting time courses for each type of stimulus confusion showed that metacontrast peaked when orientation primitives had already begun to be integrated into one object, indicated by a dominance of "no target" responses given to plaid stimuli at SOAs around 70 ms. At SOAs around 10 to 30 ms masking also had a significant impact but acted on separable components, indicated by a dominance of "orthogonal" responses given plaid stimuli. Probability summation of "no target" responses given simple gratings revealed that only at shorter SOAs performance for plaid stimuli could be predicted assuming independent features but not at SOAs of at 50-70 ms. We discuss in how far these results could also be explained by the dynamics of cross-orientation suppression (COS) and how they might relate to the process of feature integration in plaids.

  9. Light Water Reactor Sustainability Program Integrated Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    George Griffith; Robert Youngblood; Jeremy Busby; Bruce Hallbert; Cathy Barnard; Kathryn McCarthy

    2012-01-01

    Nuclear power has safely, reliably, and economically contributed almost 20% of electrical generation in the United States over the past two decades. It remains the single largest contributor (more than 70%) of non-greenhouse-gas-emitting electric power generation in the United States. Domestic demand for electrical energy is expected to experience a 31% growth from 2009 to 2035. At the same time, most of the currently operating nuclear power plants will begin reaching the end of their initial 20-year extension to their original 40-year operating license for a total of 60 years of operation. Figure E-1 shows projected nuclear energy contribution to the domestic generating capacity. If current operating nuclear power plants do not operate beyond 60 years, the total fraction of generated electrical energy from nuclear power will begin to decline - even with the expected addition of new nuclear generating capacity. The oldest commercial plants in the United States reached their 40th anniversary in 2009. The U.S. Department of Energy Office of Nuclear Energy's Research and Development Roadmap (Nuclear Energy Roadmap) organizes its activities around four objectives that ensure nuclear energy remains a compelling and viable energy option for the United States. The four objectives are as follows: (1) develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the life of the current reactors; (2) develop improvements in the affordability of new reactors to enable nuclear energy to help meet the Administration's energy security and climate change goals; (3) develop sustainable nuclear fuel cycles; and (4) understand and minimize the risks of nuclear proliferation and terrorism. The Light Water Reactor Sustainability (LWRS) Program is the primary programmatic activity that addresses Objective 1. This document summarizes the LWRS Program's plans.

  10. Light Water Reactor Sustainability Program: Integrated Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-05-01

    proliferation and terrorism. The Light Water Reactor Sustainability (LWRS) Program is the primary programmatic activity that addresses Objective 1. This document summarizes the LWRS Program’s plans. For the LWRS Program, sustainability is defined as the ability to maintain safe and economic operation of the existing fleet of nuclear power plants for a longer-than-initially-licensed lifetime. It has two facets with respect to long-term operations: (1) manage the aging of plant systems, structures, and components so that nuclear power plant lifetimes can be extended and the plants can continue to operate safely, efficiently, and economically; and (2) provide science-based solutions to the industry to implement technology to exceed the performance of the current labor-intensive business model.

  11. Feature Integration across the Lifespan: Stickier Stimulus-Response Bindings in Children and Older Adults

    Directory of Open Access Journals (Sweden)

    Bernhard Hommel

    2011-11-01

    Full Text Available Humans integrate the features of perceived events and of action plans into episodic event files. Here we investigated whether children (9-10 years, younger adults (20-31 years, and older adults (64-76 years differ in the flexibility of managing (creating and updating event files. Relative to young adults, performance in children and older adults was more hampered by partial mismatches between present and previous stimulus-response relations, suggesting less efficient updating of episodic stimulus-response representations in childhood and old age. Results are discussed in relation to changes in cortical neurochemistry during maturation and senescence.

  12. Boosting program integrity and effectiveness of the cognitive behavioral program EQUIP for incarcerated youth in The Netherlands

    NARCIS (Netherlands)

    Helmond, P.; Overbeek, G.; Brugman, D.

    2014-01-01

    This study examined whether a "program integrity booster" could improve the low to moderate program integrity and effectiveness of the EQUIP program for incarcerated youth as practiced in The Netherlands. Program integrity was assessed in EQUIP groups before and after the booster. Youth residing in

  13. Light Water Reactor Sustainability Program Integrated Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Kathryn McCarthy; Jeremy Busby; Bruce Hallbert; Shannon Bragg-Sitton; Curtis Smith; Cathy Barnard

    2013-04-01

    Nuclear power has safely, reliably, and economically contributed almost 20% of electrical generation in the United States over the past two decades. It remains the single largest contributor (more than 70%) of non-greenhouse-gas-emitting electric power generation in the United States. Domestic demand for electrical energy is expected to experience a 31% growth from 2009 to 2035. At the same time, most of the currently operating nuclear power plants will begin reaching the end of their initial 20-year extension to their original 40-year operating license for a total of 60 years of operation. Figure E-1 shows projected nuclear energy contribution to the domestic generating capacity. If current operating nuclear power plants do not operate beyond 60 years, the total fraction of generated electrical energy from nuclear power will begin to decline—even with the expected addition of new nuclear generating capacity. The oldest commercial plants in the United States reached their 40th anniversary in 2009. The U.S. Department of Energy Office of Nuclear Energy’s Research and Development Roadmap (Nuclear Energy Roadmap) organizes its activities around four objectives that ensure nuclear energy remains a compelling and viable energy option for the United States. The four objectives are as follows: (1) develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the life of the current reactors; (2) develop improvements in the affordability of new reactors to enable nuclear energy to help meet the Administration’s energy security and climate change goals; (3) develop sustainable nuclear fuel cycles; and (4) understand and minimize the risks of nuclear proliferation and terrorism. The Light Water Reactor Sustainability (LWRS) Program is the primary programmatic activity that addresses Objective 1. This document summarizes the LWRS Program’s plans.

  14. Light Water Reactor Sustainability Program Integrated Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    McCarthy, Kathryn A. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Busby, Jeremy [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hallbert, Bruce [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bragg-Sitton, Shannon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Smith, Curtis [Idaho National Lab. (INL), Idaho Falls, ID (United States); Barnard, Cathy [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-04-01

    Nuclear power has safely, reliably, and economically contributed almost 20% of electrical generation in the United States over the past two decades. It remains the single largest contributor (more than 70%) of non-greenhouse-gas-emitting electric power generation in the United States. Domestic demand for electrical energy is expected to experience a 31% growth from 2009 to 2035. At the same time, most of the currently operating nuclear power plants will begin reaching the end of their initial 20-year extension to their original 40-year operating license for a total of 60 years of operation. Figure E-1 shows projected nuclear energy contribution to the domestic generating capacity. If current operating nuclear power plants do not operate beyond 60 years, the total fraction of generated electrical energy from nuclear power will begin to decline—even with the expected addition of new nuclear generating capacity. The oldest commercial plants in the United States reached their 40th anniversary in 2009. The U.S. Department of Energy Office of Nuclear Energy’s Research and Development Roadmap (Nuclear Energy Roadmap) organizes its activities around four objectives that ensure nuclear energy remains a compelling and viable energy option for the United States. The four objectives are as follows: (1) develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the life of the current reactors; (2) develop improvements in the affordability of new reactors to enable nuclear energy to help meet the Administration’s energy security and climate change goals; (3) develop sustainable nuclear fuel cycles; and (4) understand and minimize the risks of nuclear proliferation and terrorism. The Light Water Reactor Sustainability (LWRS) Program is the primary programmatic activity that addresses Objective 1. This document summarizes the LWRS Program’s plans.

  15. Integrating Program Theory and Systems-Based Procedures in Program Evaluation: A Dynamic Approach to Evaluate Educational Programs

    Science.gov (United States)

    Grammatikopoulos, Vasilis

    2012-01-01

    The current study attempts to integrate parts of program theory and systems-based procedures in educational program evaluation. The educational program that was implemented, called the "Early Steps" project, proposed that physical education can contribute to various educational goals apart from the usual motor skills improvement. Basic…

  16. Quantitative breast mass classification based on the integration of B-mode features and strain features in elastography.

    Science.gov (United States)

    Lo, Chung-Ming; Chang, Yeun-Chung; Yang, Ya-Wen; Huang, Chiun-Sheng; Chang, Ruey-Feng

    2015-09-01

    Elastography is a new sonographic imaging technique to acquire the strain information of tissues and transform the information into images. Radiologists have to observe the gray-scale distribution of tissues on the elastographic image interpreted as the reciprocal of Young's modulus to evaluate the pathological changes such as scirrhous carcinoma. In this study, a computer-aided diagnosis (CAD) system was developed to extract quantitative strain features from elastographic images to reduce operator-dependence and provide an automatic procedure for breast mass classification. The collected image database was composed of 45 malignant and 45 benign breast masses. For each case, tumor segmentation was performed on the B-mode image to obtain tumor contour which was then mapped to the elastographic images to define the corresponding tumor area. The gray-scale pixels around tumor area were classified into white, gray, and black by fuzzy c-means clustering to highlight stiff tissues with darker values. Quantitative strain features were then extracted from the black cluster and compared with the B-mode features in the classification of breast masses. The performance of the proposed strain features achieved an accuracy of 80% (72/90), a sensitivity of 80% (36/45), a specificity of 80% (36/45), and a normalized area under the receiver operating characteristic curve, Az=0.84. Combining the strain features with the B-mode features obtained a significantly better Az=0.93, p-value<0.05. Summarily, the quantified strain features can be combined with the B-mode features to provide a promising suggestion in distinguishing malignant from benign tumors. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Combining heterogeneous features for colonic polyp detection in CTC based on semi-definite programming

    Science.gov (United States)

    Wang, Shijun; Yao, Jianhua; Petrick, Nicholas A.; Summers, Ronald M.

    2009-02-01

    Colon cancer is the second leading cause of cancer-related deaths in the United States. Computed tomographic colonography (CTC) combined with a computer aided detection system provides a feasible combination for improving colonic polyps detection and increasing the use of CTC for colon cancer screening. To distinguish true polyps from false positives, various features extracted from polyp candidates have been proposed. Most of these features try to capture the shape information of polyp candidates or neighborhood knowledge about the surrounding structures (fold, colon wall, etc.). In this paper, we propose a new set of shape descriptors for polyp candidates based on statistical curvature information. These features, called histogram of curvature features, are rotation, translation and scale invariant and can be treated as complementing our existing feature set. Then in order to make full use of the traditional features (defined as group A) and the new features (group B) which are highly heterogeneous, we employed a multiple kernel learning method based on semi-definite programming to identify an optimized classification kernel based on the combined set of features. We did leave-one-patient-out test on a CTC dataset which contained scans from 50 patients (with 90 6-9mm polyp detections). Experimental results show that a support vector machine (SVM) based on the combined feature set and the semi-definite optimization kernel achieved higher FROC performance compared to SVMs using the two groups of features separately. At a false positive per patient rate of 7, the sensitivity on 6-9mm polyps using the combined features improved from 0.78 (Group A) and 0.73 (Group B) to 0.82 (p<=0.01).

  18. Class-Pair Multiple Kernel Learning of Integrating Heterogeneous Features for Classification

    Science.gov (United States)

    Wang, Q.; Gu, Y.; Liu, T.; Liu, H.; Jin, X.

    2017-10-01

    In recent years, many studies on remote sensing image classification have shown that using multiple features from different data sources can effectively improve the classification accuracy. As a very powerful means of learning, multiple kernel learning (MKL) can conveniently be embedded in a variety of characteristics. The conventional combined kernel learned by MKL can be regarded as the compromise of all basic kernels for all classes in classification. It is the best of the whole, but not optimal for each specific class. For this problem, this paper proposes a class-pair-guided MKL method to integrate the heterogeneous features (HFs) from multispectral image (MSI) and light detection and ranging (LiDAR) data. In particular, the one-against-one strategy is adopted, which converts multiclass classification problem to a plurality of two-class classification problem. Then, we select the best kernel from pre-constructed basic kernels set for each class-pair by kernel alignment (KA) in the process of classification. The advantage of the proposed method is that only the best kernel for the classification of any two classes can be retained, which leads to greatly enhanced discriminability. Experiments are conducted on two real data sets, and the experimental results show that the proposed method achieves the best performance in terms of classification accuracies in integrating the HFs for classification when compared with several state-of-the-art algorithms.

  19. MULTI-SCALE SEGMENTATION OF HIGH RESOLUTION REMOTE SENSING IMAGES BY INTEGRATING MULTIPLE FEATURES

    Directory of Open Access Journals (Sweden)

    Y. Di

    2017-05-01

    Full Text Available Most of multi-scale segmentation algorithms are not aiming at high resolution remote sensing images and have difficulty to communicate and use layers’ information. In view of them, we proposes a method of multi-scale segmentation of high resolution remote sensing images by integrating multiple features. First, Canny operator is used to extract edge information, and then band weighted distance function is built to obtain the edge weight. According to the criterion, the initial segmentation objects of color images can be gained by Kruskal minimum spanning tree algorithm. Finally segmentation images are got by the adaptive rule of Mumford–Shah region merging combination with spectral and texture information. The proposed method is evaluated precisely using analog images and ZY-3 satellite images through quantitative and qualitative analysis. The experimental results show that the multi-scale segmentation of high resolution remote sensing images by integrating multiple features outperformed the software eCognition fractal network evolution algorithm (highest-resolution network evolution that FNEA on the accuracy and slightly inferior to FNEA on the efficiency.

  20. Relevant Feature Integration and Extraction for Single-Trial Motor Imagery Classification

    Directory of Open Access Journals (Sweden)

    Lili Li

    2017-06-01

    Full Text Available Brain computer interfaces provide a novel channel for the communication between brain and output devices. The effectiveness of the brain computer interface is based on the classification accuracy of single trial brain signals. The common spatial pattern (CSP algorithm is believed to be an effective algorithm for the classification of single trial brain signals. As the amplitude feature for spatial projection applied by this algorithm is based on a broad frequency bandpass filter (mainly 5–30 Hz in which the frequency band is often selected by experience, the CSP is sensitive to noise and the influence of other irrelevant information in the selected broad frequency band. In this paper, to improve the CSP, a novel relevant feature integration and extraction algorithm is proposed. Before projecting, we integrated the motor relevant information to suppress the interference of noise and irrelevant information, as well as to improve the spatial difference for projection. The algorithm was evaluated with public datasets. It showed significantly better classification performance with single trial electroencephalography (EEG data, increasing by 6.8% compared with the CSP.

  1. Danish integrated antimicrobial in resistance monitoring and research program

    DEFF Research Database (Denmark)

    Hammerum, Anette Marie; Heuer, Ole Eske; Emborg, Hanne-Dorthe

    2007-01-01

    Resistance to antimicrobial agents is an emerging problem worldwide. Awareness of the undesirable consequences of its widespread occurrence has led to the initiation of antimicrobial agent resistance monitoring programs in several countries. In 1995, Denmark was the first country to establish...... a systematic and continuous monitoring program of antimicrobial drug consumption and antimicrobial agent resistance in animals, food, and humans, the Danish Integrated Antimicrobial Resistance Monitoring and Research Program (DANMAP). Monitoring of antimicrobial drug resistance and a range of research...... activities related to DANMAP have contributed to restrictions or bans of use of several antimicrobial agents in food animals in Denmark and other European Union countries....

  2. DOE SunShot System Integration Program. Accomplishments and Impacts

    Energy Technology Data Exchange (ETDEWEB)

    Boynton, Shannon [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ellis, Abraham [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-02-01

    During FY15, Sandia National Laboratories executed research and development (R&D) work on a portfolio of 16 SunShot Program Systems Integration (SI) agreements, with a total FY15 budget of $13.2 million. This document summarizes the impact of the Sandia contributions based on Sandia’s direct contributions by DOE.

  3. A mixed integer linear program for an integrated fishery | Hasan ...

    African Journals Online (AJOL)

    We develop a mixed integer linear programming (MILP) model to co-ordinate trawler scheduling, fishing, processing, and labour allocation of quota based integrated fisheries. We demonstrate the workability of our model with a numerical example and sensitivity analysis based on data obtained from one of the major ...

  4. What is Program Collaboration and Service Integration (PCSI)?

    Centers for Disease Control (CDC) Podcasts

    2009-12-07

    This podcast provides a description of Program Collaboration and Service Integration (PCSI).  Created: 12/7/2009 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 12/7/2009.

  5. Integrating Global Content into Special Education Teacher Preparation Programs

    Science.gov (United States)

    Xin, Joy F.; Accardo, Amy L.; Shuff, Midge; Cormier, Mary; Doorman, Diane

    2016-01-01

    Globalization affects many aspects of our lives in the 21st century and requires us to adopt an international perspective. For this study, global content was integrated into one course of an undergraduate special education teacher education program. A total of 118 teacher candidates were enrolled in the course over two semesters. A pre-post test…

  6. Integral Fast Reactor Program. Annual progress report, FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

    1993-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1992. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  7. Planning integration FY 1996 program plan. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This Multi-Year Program Plan (MAP) Planning Integration Program, Work Breakdown Structure (WBS) Element 1.8.2, is the primary management tool to document the technical, schedule, and cost baseline for work directed by the US Department of Energy (DOE), Richland Operations Office (RL). As an approved document, it establishes an agreement between RL and the performing contractors for the work to be performed. It was prepared by Westinghouse Hanford Company (WHC) and Pacific Northwest Laboratory (PNL). The MYPPs for the Hanford Site programs are to provide a picture from fiscal year (FY) 1996 through FY 2002. At RL Planning and Integration Division (PID) direction, only the FY 1996 Planning Integration Program work scope has been planned and presented in this MAP. Only those known significant activities which occur after FY 1996 are portrayed in this MAP. This is due to the uncertainty of who will be accomplishing what work scope when, following the award of the Management and Integration (M&I) contract.

  8. Hawaii Integrated Biofuels Research Program: Final Subcontract Report, Phase III

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    This report is a compilation of studies done to develop an integrated set of strategies for the production of energy from renewable resources in Hawaii. Because of the close coordination between this program and other ongoing DOE research, the work will have broad-based applicability to the entire United States.

  9. Integral Fast Reactor Program annual progress report, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  10. Integral Fast Reactor Program annual progress report, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R D.

  11. Integral Fast Reactor Program annual progress report, FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, J.J.

    1994-12-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1994. Technical accomplishments are presented in the following areas of the IFR technology development activities: metal fuel performance; pyroprocess development; safety experiments and analyses; core design development; fuel cycle demonstration; and LMR technology R&D.

  12. Biomass Program 2007 Peer Review - Integrated Biorefinery Platform Summary

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2009-10-27

    This document discloses the comments provided by a review panel at the U.S. Department of Energy Office of the Biomass Program Peer Review held on November 15-16, 2007 in Baltimore, MD and the Integrated Biorefinery Platform Review held on August 13-15, 2007 in Golden, Colorado.

  13. Integration of Absorption Feature Information from Visible to Longwave Infrared Spectral Ranges for Mineral Mapping

    Directory of Open Access Journals (Sweden)

    Veronika Kopačková

    2017-09-01

    Full Text Available Merging hyperspectral data from optical and thermal ranges allows a wider variety of minerals to be mapped and thus allows lithology to be mapped in a more complex way. In contrast, in most of the studies that have taken advantage of the data from the visible (VIS, near-infrared (NIR, shortwave infrared (SWIR and longwave infrared (LWIR spectral ranges, these different spectral ranges were analysed and interpreted separately. This limits the complexity of the final interpretation. In this study a presentation is made of how multiple absorption features, which are directly linked to the mineral composition and are present throughout the VIS, NIR, SWIR and LWIR ranges, can be automatically derived and, moreover, how these new datasets can be successfully used for mineral/lithology mapping. The biggest advantage of this approach is that it overcomes the issue of prior definition of endmembers, which is a requested routine employed in all widely used spectral mapping techniques. In this study, two different airborne image datasets were analysed, HyMap (VIS/NIR/SWIR image data and Airborne Hyperspectral Scanner (AHS, LWIR image data. Both datasets were acquired over the Sokolov lignite open-cast mines in the Czech Republic. It is further demonstrated that even in this case, when the absorption feature information derived from multispectral LWIR data is integrated with the absorption feature information derived from hyperspectral VIS/NIR/SWIR data, an important improvement in terms of more complex mineral mapping is achieved.

  14. 25 CFR 39.132 - Can a school integrate Language Development programs into its regular instructional program?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Can a school integrate Language Development programs into... Language Development Programs § 39.132 Can a school integrate Language Development programs into its regular instructional program? A school may offer Language Development programs to students as part of its...

  15. Achieving High Reliability Operations Through Multi-Program Integration

    Energy Technology Data Exchange (ETDEWEB)

    Holly M. Ashley; Ronald K. Farris; Robert E. Richards

    2009-04-01

    Over the last 20 years the Idaho National Laboratory (INL) has adopted a number of operations and safety-related programs which has each periodically taken its turn in the limelight. As new programs have come along there has been natural competition for resources, focus and commitment. In the last few years, the INL has made real progress in integrating all these programs and are starting to realize important synergies. Contributing to this integration are both collaborative individuals and an emerging shared vision and goal of the INL fully maturing in its high reliability operations. This goal is so powerful because the concept of high reliability operations (and the resulting organizations) is a masterful amalgam and orchestrator of the best of all the participating programs (i.e. conduct of operations, behavior based safety, human performance, voluntary protection, quality assurance, and integrated safety management). This paper is a brief recounting of the lessons learned, thus far, at the INL in bringing previously competing programs into harmony under the goal (umbrella) of seeking to perform regularly as a high reliability organization. In addition to a brief diagram-illustrated historical review, the authors will share the INL’s primary successes (things already effectively stopped or started) and the gaps yet to be bridged.

  16. The implication of integrated training program for medical history education

    Directory of Open Access Journals (Sweden)

    Shun-Sheng Chen

    2015-02-01

    Full Text Available Background: A full spectrum of medical education requires not only clinical skills but also humanistic qualities in the medical professionals, which can be facilitated by an integrated training program. An integrated project was created to improve one's medical intellectual and communication competence and to enable them to become docents who can perform well, as well as for development of their humanitarian nature. The aim of this study was to suggest an integrated program that provided approaches for creating positive effects in medical history education. Methods: Taiwan Medical Museum conducted a project on medical history lessons and docent training program; 51 participants (24 male and 27 female attended this plan. Targets took pre-tests before lectures, attended courses of medical history, and then took post-tests. Next, they received a series of lessons on presentation skills and practiced for guiding performance. After all the training processes, the attendees succeeded in all evaluations in order to guide exhibition visitors. Data were analyzed using paired t test. Results: Two types of assessments were followed, i.e., cognitive examination and guiding practice, and both were related to good performance. Reliability (Cronbach's α was 0.737 for the cognitive examination and 0.87 for the guiding evaluation. It indicated that the integrated program for docent training resulted in a significant difference (p ≦ 0.0001. Conclusion: The participants demonstrated better achievement and knowledge acquisition through the entire process, which led to great performance when approached by the visitors. The whole project helped to shape up a good docent and to accumulate positive learning experiences for medical professionals as well. Therefore, an integrated program is recommended to medical history education in the future.

  17. Multi-Objective Genetic Programming with Redundancy-Regulations for Automatic Construction of Image Feature Extractors

    Science.gov (United States)

    Watchareeruetai, Ukrit; Matsumoto, Tetsuya; Takeuchi, Yoshinori; Kudo, Hiroaki; Ohnishi, Noboru

    We propose a new multi-objective genetic programming (MOGP) for automatic construction of image feature extraction programs (FEPs). The proposed method was originated from a well known multi-objective evolutionary algorithm (MOEA), i.e., NSGA-II. The key differences are that redundancy-regulation mechanisms are applied in three main processes of the MOGP, i.e., population truncation, sampling, and offspring generation, to improve population diversity as well as convergence rate. Experimental results indicate that the proposed MOGP-based FEP construction system outperforms the two conventional MOEAs (i.e., NSGA-II and SPEA2) for a test problem. Moreover, we compared the programs constructed by the proposed MOGP with four human-designed object recognition programs. The results show that the constructed programs are better than two human-designed methods and are comparable with the other two human-designed methods for the test problem.

  18. Information Requirements for Integrating Spatially Discrete, Feature-Based Earth Observations

    Science.gov (United States)

    Horsburgh, J. S.; Aufdenkampe, A. K.; Lehnert, K. A.; Mayorga, E.; Hsu, L.; Song, L.; Zaslavsky, I.; Valentine, D. L.

    2014-12-01

    Several cyberinfrastructures have emerged for sharing observational data collected at densely sampled and/or highly instrumented field sites. These include the CUAHSI Hydrologic Information System (HIS), the Critical Zone Observatory Integrated Data Management System (CZOData), the Integrated Earth Data Applications (IEDA) and EarthChem system, and the Integrated Ocean Observing System (IOOS). These systems rely on standard data encodings and, in some cases, standard semantics for classes of geoscience data. Their focus is on sharing data on the Internet via web services in domain specific encodings or markup languages. While they have made progress in making data available, it still takes investigators significant effort to discover and access datasets from multiple repositories because of inconsistencies in the way domain systems describe, encode, and share data. Yet, there are many scenarios that require efficient integration of these data types across different domains. For example, understanding a soil profile's geochemical response to extreme weather events requires integration of hydrologic and atmospheric time series with geochemical data from soil samples collected over various depth intervals from soil cores or pits at different positions on a landscape. Integrated access to and analysis of data for such studies are hindered because common characteristics of data, including time, location, provenance, methods, and units are described differently within different systems. Integration requires syntactic and semantic translations that can be manual, error-prone, and lossy. We report information requirements identified as part of our work to define an information model for a broad class of earth science data - i.e., spatially-discrete, feature-based earth observations resulting from in-situ sensors and environmental samples. We sought to answer the question: "What information must accompany observational data for them to be archivable and discoverable within

  19. The Temporal Dynamics of Feature Integration for Color, form, and Motion

    Directory of Open Access Journals (Sweden)

    KS Pilz

    2012-07-01

    Full Text Available When two similar visual stimuli are presented in rapid succession, only their fused image is perceived, without having conscious access to the single stimuli. Such feature fusion occurs both for color (eg, Efron1973 and form (eg, Scharnowski et al 2007. For verniers, the fusion process lasts for more than 400 ms, as has been shown using TMS (Scharnowski et al 2009. In three experiments, we used light masks to investigate the time course of feature fusion for color, form, and motion. In experiment one, two verniers were presented in rapid succession with opposite offset directions. Subjects had to indicate the offset direction of the vernier. In a second experiment, a red and a green disk were presented in rapid succession, and subjects had to indicate whether the fused, yellow disk appeared rather than red or green. In a third experiment, three frames of random dots were presented successively. The first two frames created a percept of apparent motion to the upper right; and the last two frames, one to the upper left or vice versa. Subjects had to indicate the direction of motion. All stimuli were presented foveally. In all three experiments, we first balanced performance so that neither the first nor the second stimulus dominated the fused percept. In a second step, a light mask was presented either before, during, or after stimulus presentation. Depending on presentation time, the light masks modulated the fusion process so that either the first or the second stimulus dominated the percept. Our results show that unconscious feature fusion lasts more than five times longer than the actual stimulus duration, which indicates that individual features are stored for a substantial amount of time before they are integrated.

  20. Feature context-dependency and complexity-reduction in probability landscapes for integrative genomics.

    Science.gov (United States)

    Lesne, Annick; Benecke, Arndt

    2008-09-10

    The question of how to integrate heterogeneous sources of biological information into a coherent framework that allows the gene regulatory code in eukaryotes to be systematically investigated is one of the major challenges faced by systems biology. Probability landscapes, which include as reference set the probabilistic representation of the genomic sequence, have been proposed as a possible approach to the systematic discovery and analysis of correlations amongst initially heterogeneous and un-relatable descriptions and genome-wide measurements. Much of the available experimental sequence and genome activity information is de facto, but not necessarily obviously, context dependent. Furthermore, the context dependency of the relevant information is itself dependent on the biological question addressed. It is hence necessary to develop a systematic way of discovering the context-dependency of functional genomics information in a flexible, question-dependent manner. We demonstrate here how feature context-dependency can be systematically investigated using probability landscapes. Furthermore, we show how different feature probability profiles can be conditionally collapsed to reduce the computational and formal, mathematical complexity of probability landscapes. Interestingly, the possibility of complexity reduction can be linked directly to the analysis of context-dependency. These two advances in our understanding of the properties of probability landscapes not only simplify subsequent cross-correlation analysis in hypothesis-driven model building and testing, but also provide additional insights into the biological gene regulatory problems studied. Furthermore, insights into the nature of individual features and a classification of features according to their minimal context-dependency are achieved. The formal structure proposed contributes to a concrete and tangible basis for attempting to formulate novel mathematical structures for describing gene regulation in

  1. International Piping Integrity Research Group (IPIRG) Program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Wilkowski, G.; Schmidt, R.; Scott, P. [and others

    1997-06-01

    This is the final report of the International Piping Integrity Research Group (IPIRG) Program. The IPIRG Program was an international group program managed by the U.S. Nuclear Regulatory Commission and funded by a consortium of organizations from nine nations: Canada, France, Italy, Japan, Sweden, Switzerland, Taiwan, the United Kingdom, and the United States. The program objective was to develop data needed to verify engineering methods for assessing the integrity of circumferentially-cracked nuclear power plant piping. The primary focus was an experimental task that investigated the behavior of circumferentially flawed piping systems subjected to high-rate loadings typical of seismic events. To accomplish these objectives a pipe system fabricated as an expansion loop with over 30 meters of 16-inch diameter pipe and five long radius elbows was constructed. Five dynamic, cyclic, flawed piping experiments were conducted using this facility. This report: (1) provides background information on leak-before-break and flaw evaluation procedures for piping, (2) summarizes technical results of the program, (3) gives a relatively detailed assessment of the results from the pipe fracture experiments and complementary analyses, and (4) summarizes advances in the state-of-the-art of pipe fracture technology resulting from the IPIRG program.

  2. Spermatogenesis-specific features of the meiotic program in Caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Diane C Shakes

    2009-08-01

    Full Text Available In most sexually reproducing organisms, the fundamental process of meiosis is implemented concurrently with two differentiation programs that occur at different rates and generate distinct cell types, sperm and oocytes. However, little is known about how the meiotic program is influenced by such contrasting developmental programs. Here we present a detailed timeline of late meiotic prophase during spermatogenesis in Caenorhabditis elegans using cytological and molecular landmarks to interrelate changes in chromosome dynamics with germ cell cellularization, spindle formation, and cell cycle transitions. This analysis expands our understanding C. elegans spermatogenesis, as it identifies multiple spermatogenesis-specific features of the meiotic program and provides a framework for comparative studies. Post-pachytene chromatin of spermatocytes is distinct from that of oocytes in both composition and morphology. Strikingly, C. elegans spermatogenesis includes a previously undescribed karyosome stage, a common but poorly understood feature of meiosis in many organisms. We find that karyosome formation, in which chromosomes form a constricted mass within an intact nuclear envelope, follows desynapsis, involves a global down-regulation of transcription, and may support the sequential activation of multiple kinases that prepare spermatocytes for meiotic divisions. In spermatocytes, the presence of centrioles alters both the relative timing of meiotic spindle assembly and its ultimate structure. These microtubule differences are accompanied by differences in kinetochores, which connect microtubules to chromosomes. The sperm-specific features of meiosis revealed here illuminate how the underlying molecular machinery required for meiosis is differentially regulated in each sex.

  3. An Innovative Course Featuring Action Research Integrated with Unifying Science Themes

    Science.gov (United States)

    Otto, Charlotte A.; Luera, Gail R.; Everett, Susan A.

    2009-12-01

    In this article, we describe an innovative capstone course for preservice K-8 teachers integrating action research and a unifying theme in science (AAAS in Science for all Americans. Oxford University Press, New York, 1989; NRC in National science education standards. National Academy Press, Washington, DC, 1996). The goals of the capstone course are to increase student knowledge of the unifying theme, improve written communication skills, and introduce students to educational research. We provide evidence that each of these goals is met. Student growth in theme knowledge is demonstrated through concept maps, questionnaires, and previously reported assessments. Improved writing ability is demonstrated using the spelling and grammar checking feature of Microsoft Word. The analysis of action research reports demonstrates that students are able to connect their action research project results to previous research.

  4. Sparse Bayesian Regression with Integrated Feature Selection for Nuclear Reactor Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Dayman, Ken J [ORNL; Ade, Brian J [ORNL; Weber, Charles F [ORNL

    2017-01-01

    High-dimensional, nonlinear function estimation using large datasets is a current area of interest in the machine learning community, and applications may be found throughout the analytical sciences, where ever-growing datasets are making more information available to the analyst. In this paper, we leverage the existing relevance vector machine, a sparse Bayesian version of the well-studied support vector machine, and expand the method to include integrated feature selection and automatic function shaping. These innovations produce an algorithm that is able to distinguish variables that are useful for making predictions of a response from variables that are unrelated or confusing. We test the technology using synthetic data, conduct initial performance studies, and develop a model capable of making position-independent predictions of the coreaveraged burnup using a single specimen drawn randomly from a nuclear reactor core.

  5. Integral urban solid waste management program in a Mexican university.

    Science.gov (United States)

    Espinosa, R M; Turpin, S; Polanco, G; De Latorre, A; Delfín, I; Raygoza, I

    2008-01-01

    The Azcapotzalco campus of the Universidad Autónoma Metropolitana (UAM-A) has implemented an Integral Urban Solid Waste Management Program, "Segregation for a Better UAM Environment" (Separacción por un mejor UAMbiente). This program is directed to create awareness and involve the academic community of the UAM-A concerning the problem of solid wastes, at the same time fulfilling the local environmental legislation. The program consists in separating solid wastes into two classes: (1) recoverable wastes (glass and PET bottles, aluminum cans, Tetrapak packages) and (2) other wastes (non-recoverable). During the past three years, thanks to this program, the amount of solid wastes delivered monthly to municipal collecting services has been considerably reduced. In this period, UAM-A has sent to recycling: 2.2 tons of glass bottles; 2.3 tons of PET bottles; 1.2 tons of Tetrapak packages and 27.5 kg of aluminum cans.

  6. The features of teaching methods of programming in the system of supplementary education in informatics and ICT

    National Research Council Canada - National Science Library

    Наталья Геннадьевна Саблукова

    2010-01-01

    The model of formation of the rational contents of teaching to programming in described in the article in view of specificity of supplementary education and features of visual surroundings of programming...

  7. Features of Norwegian model of the integration with the EU: experience for Ukraine

    Directory of Open Access Journals (Sweden)

    O. M. Rudik

    2017-03-01

    determined that the key negative feature of Norwegian model of relations with the EU is «integration without representation», which means that Norway is not represented in the EU decision-making processes. But these processes actually determine the development of Norwegian legislation and policy. It has been grounded that in terms of international law and practice of international cooperation, the Norwegian model of relations with the EU is exceptional. Now the European Union does not see the perspective for Ukraine to get the EU membership. Consequently, it has been suggested that in such circumstances Norway experience can be very useful for Ukraine, particularly in the context of development of ever closer relations with the EU, and the integration of national economy into the EU internal market.

  8. Integrating Climate Change Resilience Features into the Incremental Refinement of an Existing Marine Park.

    Science.gov (United States)

    Davies, Harriet N; Beckley, Lynnath E; Kobryn, Halina T; Lombard, Amanda T; Radford, Ben; Heyward, Andrew

    2016-01-01

    Marine protected area (MPA) designs are likely to require iterative refinement as new knowledge is gained. In particular, there is an increasing need to consider the effects of climate change, especially the ability of ecosystems to resist and/or recover from climate-related disturbances, within the MPA planning process. However, there has been limited research addressing the incorporation of climate change resilience into MPA design. This study used Marxan conservation planning software with fine-scale shallow water (change resilience features to integrate into the incremental refinement of the marine park. The study assessed the representation of benthic habitats within the current marine park zones, identified priority areas of high resilience for inclusion within no-take zones and examined if any iterative refinements to the current no-take zones are necessary. Of the 65 habitat classes, 16 did not meet representation targets within the current no-take zones, most of which were in deeper offshore waters. These deeper areas also demonstrated the highest resilience values and, as such, Marxan outputs suggested minor increases to the current no-take zones in the deeper offshore areas. This work demonstrates that inclusion of fine-scale climate change resilience features within the design process for MPAs is feasible, and can be applied to future marine spatial planning practices globally.

  9. Report of the Integrated Program Planning Activity for the DOE Fusion Energy Sciences Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-12-01

    This report of the Integrated Program Planning Activity (IPPA) has been prepared in response to a recommendation by the Secretary of Energy Advisory Board that, ''Given the complex nature of the fusion effort, an integrated program planning process is an absolute necessity.'' We, therefore, undertook this activity in order to integrate the various elements of the program, to improve communication and performance accountability across the program, and to show the inter-connectedness and inter-dependency of the diverse parts of the national fusion energy sciences program. This report is based on the September 1999 Fusion Energy Sciences Advisory Committee's (FESAC) report ''Priorities and Balance within the Fusion Energy Sciences Program''. In its December 5,2000, letter to the Director of the Office of Science, the FESAC has reaffirmed the validity of the September 1999 report and stated that the IPPA presents a framework and process to guide the achievement of the 5-year goals listed in the 1999 report. The National Research Council's (NRC) Fusion Assessment Committee draft final report ''An Assessment of the Department of Energy's Office of Fusion Energy Sciences Program'', reviewing the quality of the science in the program, was made available after the IPPA report had been completed. The IPPA report is, nevertheless, consistent with the recommendations in the NRC report. In addition to program goals and the related 5-year, 10-year, and 15-year objectives, this report elaborates on the scientific issues associated with each of these objectives. The report also makes clear the relationships among the various program elements, and cites these relationships as the reason why integrated program planning is essential. In particular, while focusing on the science conducted by the program, the report addresses the important balances between the science and energy goals of the program, between the

  10. AN INTEGRATIVE GROUP PSYCHOTHERAPY PROGRAM FOR CHILDREN. THE WIZARDING SCHOOL

    Directory of Open Access Journals (Sweden)

    Oana Maria Popescu

    2012-02-01

    Full Text Available One of the most important tendencies in child psychotherapy is the integration of various psychotherapeutic approaches and technical interventions belonging to different orientations. Based on the Harry Potter stories, the „Wizarding School” structured group therapy program is a 12-step integratively oriented program applicable in personal development, individual and group therapy for children aged 6 to 13 (at present being adapted for adult psychotherapy. The program takes place within a fairy tale, being therefore a type of informal hypnotic trance. The interventions are drawn from the lessons described in Harry Potter’s story at Hogwarts, based on the fundamental principles of child psychotherapy and including elements of play therapy, art therapy, hypnotherapy, cognitive- behavioural therapy, transactional analysis, supportive therapy, family therapy and person centred therapy. From a theoretical point of view the program is based on elements from a number of psychotherapeutic approaches, the main concept being that we need to create a therapeutic myth that is acceptable to a child. The program is not suitable for children with structural deficits, who have difficulties in making the difference between fantasy and reality.

  11. Self-Organizing Neural Integration of Pose-Motion Features for Human Action Recognition

    Directory of Open Access Journals (Sweden)

    German Ignacio Parisi

    2015-06-01

    Full Text Available The visual recognition of complex, articulated human movements is fundamental for a wide range of artificial systems oriented towards human-robot communication, action classification, and action-driven perception. These challenging tasks may generally involve the processing of a huge amount of visual information and learning-based mechanisms for generalizing a set of training actions and classifying new samples. To operate in natural environments, a crucial property is the efficient and robust recognition of actions, also under noisy conditions caused by, for instance, systematic sensor errors and temporarily occluded persons. Studies of the mammalian visual system and its outperforming ability to process biological motion information suggest separate neural pathways for the distinct processing of pose and motion features at multiple levels and the subsequent integration of these visual cues for action perception. We present a neurobiologically-motivated approach to achieve noise-tolerant action recognition in real time. Our model consists of self-organizing Growing When Required (GWR networks that obtain progressively generalized representations of sensory inputs and learn inherent spatiotemporal dependencies. During the training, the GWR networks dynamically change their topological structure to better match the input space. We first extract pose and motion features from video sequences and then cluster actions in terms of prototypical pose-motion trajectories. Multi-cue trajectories from matching action frames are subsequently combined to provide action dynamics in the joint feature space. Reported experiments show that our approach outperforms previous results on a dataset of full-body actions captured with a depth sensor, and ranks among the best 21 results for a public benchmark of domestic daily actions.

  12. PROSPER: an integrated feature-based tool for predicting protease substrate cleavage sites.

    Directory of Open Access Journals (Sweden)

    Jiangning Song

    Full Text Available The ability to catalytically cleave protein substrates after synthesis is fundamental for all forms of life. Accordingly, site-specific proteolysis is one of the most important post-translational modifications. The key to understanding the physiological role of a protease is to identify its natural substrate(s. Knowledge of the substrate specificity of a protease can dramatically improve our ability to predict its target protein substrates, but this information must be utilized in an effective manner in order to efficiently identify protein substrates by in silico approaches. To address this problem, we present PROSPER, an integrated feature-based server for in silico identification of protease substrates and their cleavage sites for twenty-four different proteases. PROSPER utilizes established specificity information for these proteases (derived from the MEROPS database with a machine learning approach to predict protease cleavage sites by using different, but complementary sequence and structure characteristics. Features used by PROSPER include local amino acid sequence profile, predicted secondary structure, solvent accessibility and predicted native disorder. Thus, for proteases with known amino acid specificity, PROSPER provides a convenient, pre-prepared tool for use in identifying protein substrates for the enzymes. Systematic prediction analysis for the twenty-four proteases thus far included in the database revealed that the features we have included in the tool strongly improve performance in terms of cleavage site prediction, as evidenced by their contribution to performance improvement in terms of identifying known cleavage sites in substrates for these enzymes. In comparison with two state-of-the-art prediction tools, PoPS and SitePrediction, PROSPER achieves greater accuracy and coverage. To our knowledge, PROSPER is the first comprehensive server capable of predicting cleavage sites of multiple proteases within a single substrate

  13. Epileptic MEG Spike Detection Using Statistical Features and Genetic Programming with KNN.

    Science.gov (United States)

    Alotaiby, Turky N; Alrshoud, Saud R; Alshebeili, Saleh A; Alhumaid, Majed H; Alsabhan, Waleed M

    2017-01-01

    Epilepsy is a neurological disorder that affects millions of people worldwide. Monitoring the brain activities and identifying the seizure source which starts with spike detection are important steps for epilepsy treatment. Magnetoencephalography (MEG) is an emerging epileptic diagnostic tool with high-density sensors; this makes manual analysis a challenging task due to the vast amount of MEG data. This paper explores the use of eight statistical features and genetic programing (GP) with the K-nearest neighbor (KNN) for interictal spike detection. The proposed method is comprised of three stages: preprocessing, genetic programming-based feature generation, and classification. The effectiveness of the proposed approach has been evaluated using real MEG data obtained from 28 epileptic patients. It has achieved a 91.75% average sensitivity and 92.99% average specificity.

  14. Epileptic MEG Spike Detection Using Statistical Features and Genetic Programming with KNN

    Directory of Open Access Journals (Sweden)

    Turky N. Alotaiby

    2017-01-01

    Full Text Available Epilepsy is a neurological disorder that affects millions of people worldwide. Monitoring the brain activities and identifying the seizure source which starts with spike detection are important steps for epilepsy treatment. Magnetoencephalography (MEG is an emerging epileptic diagnostic tool with high-density sensors; this makes manual analysis a challenging task due to the vast amount of MEG data. This paper explores the use of eight statistical features and genetic programing (GP with the K-nearest neighbor (KNN for interictal spike detection. The proposed method is comprised of three stages: preprocessing, genetic programming-based feature generation, and classification. The effectiveness of the proposed approach has been evaluated using real MEG data obtained from 28 epileptic patients. It has achieved a 91.75% average sensitivity and 92.99% average specificity.

  15. Infrared and visible images registration with adaptable local-global feature integration for rail inspection

    Science.gov (United States)

    Tang, Chaoqing; Tian, Gui Yun; Chen, Xiaotian; Wu, Jianbo; Li, Kongjing; Meng, Hongying

    2017-12-01

    Active thermography provides infrared images that contain sub-surface defect information, while visible images only reveal surface information. Mapping infrared information to visible images offers more comprehensive visualization for decision-making in rail inspection. However, the common information for registration is limited due to different modalities in both local and global level. For example, rail track which has low temperature contrast reveals rich details in visible images, but turns blurry in the infrared counterparts. This paper proposes a registration algorithm called Edge-Guided Speeded-Up-Robust-Features (EG-SURF) to address this issue. Rather than sequentially integrating local and global information in matching stage which suffered from buckets effect, this algorithm adaptively integrates local and global information into a descriptor to gather more common information before matching. This adaptability consists of two facets, an adaptable weighting factor between local and global information, and an adaptable main direction accuracy. The local information is extracted using SURF while the global information is represented by shape context from edges. Meanwhile, in shape context generation process, edges are weighted according to local scale and decomposed into bins using a vector decomposition manner to provide more accurate descriptor. The proposed algorithm is qualitatively and quantitatively validated using eddy current pulsed thermography scene in the experiments. In comparison with other algorithms, better performance has been achieved.

  16. A Call for an Integrated Program of Assessment

    Science.gov (United States)

    Regehr, Glenn

    2017-01-01

    An integrated curriculum that does not incorporate equally integrated assessment strategies is likely to prove ineffective in achieving the desired educational outcomes. We suggest it is time for colleges and schools of pharmacy to re-engineer their approach to assessment. To build the case, we first discuss the challenges leading to the need for curricular developments in pharmacy education. We then turn to the literature that informs how assessment can influence learning, introduce an approach to learning assessment that is being used by several medical education programs, and provide some examples of this approach in operation. Finally, we identify some of the challenges faced in adopting such an integrated approach to assessment and suggest that this is an area ripe with research opportunities for pharmacy educators. PMID:28630518

  17. Faculty perceptions of the integration of SAP in academic programs

    Directory of Open Access Journals (Sweden)

    Sam Khoury

    2012-08-01

    Full Text Available In order to prepare students for the workforce, academic programs incorporate a variety of tools that students are likely to use in their future careers. One of these tools employed by business and technology programs is the integration of live software applications such as SAP through the SAP University Alliance (SAP UA program. Since the SAP UA program has been around for only about 10 years and the available literature on the topic is limited, research is needed to determine the strengths and weaknesses of the SAP UA program. A collaborative study of SAP UA faculty perceptions of their SAP UAs was conducted in the fall of 2011. Of the faculty invited to participate in the study, 31% completed the online survey. The results indicate that most faculty experienced difficulty implementing SAP into their programs and report that a need exists for more standardized curriculum and training, while a large percentage indicated that they are receiving the support they need from their schools and SAP.

  18. Development of integrated programs for Aerospace-vehicle Design (IPAD): Product program management systems

    Science.gov (United States)

    Isenberg, J. M.; Southall, J. W.

    1979-01-01

    The Integrated Programs for Aerospace Vehicle Design (IPAD) is a computing system to support company-wide design information processing. This document presents a brief description of the management system used to direct and control a product-oriented program. This document, together with the reference design process (CR 2981) and the manufacture interactions with the design process (CR 2982), comprises the reference information that forms the basis for specifying IPAD system requirements.

  19. Small UAS-Based Wind Feature Identification System Part 1: Integration and Validation

    Directory of Open Access Journals (Sweden)

    Leopoldo Rodriguez Salazar

    2016-12-01

    Full Text Available This paper presents a system for identification of wind features, such as gusts and wind shear. These are of particular interest in the context of energy-efficient navigation of Small Unmanned Aerial Systems (UAS. The proposed system generates real-time wind vector estimates and a novel algorithm to generate wind field predictions. Estimations are based on the integration of an off-the-shelf navigation system and airspeed readings in a so-called direct approach. Wind predictions use atmospheric models to characterize the wind field with different statistical analyses. During the prediction stage, the system is able to incorporate, in a big-data approach, wind measurements from previous flights in order to enhance the approximations. Wind estimates are classified and fitted into a Weibull probability density function. A Genetic Algorithm (GA is utilized to determine the shaping and scale parameters of the distribution, which are employed to determine the most probable wind speed at a certain position. The system uses this information to characterize a wind shear or a discrete gust and also utilizes a Gaussian Process regression to characterize continuous gusts. The knowledge of the wind features is crucial for computing energy-efficient trajectories with low cost and payload. Therefore, the system provides a solution that does not require any additional sensors. The system architecture presents a modular decentralized approach, in which the main parts of the system are separated in modules and the exchange of information is managed by a communication handler to enhance upgradeability and maintainability. Validation is done providing preliminary results of both simulations and Software-In-The-Loop testing. Telemetry data collected from real flights, performed in the Seville Metropolitan Area in Andalusia (Spain, was used for testing. Results show that wind estimation and predictions can be calculated at 1 Hz and a wind map can be updated at 0.4 Hz

  20. Integrating Oncology Massage Into Chemoinfusion Suites: A Program Evaluation.

    Science.gov (United States)

    Mao, Jun J; Wagner, Karen E; Seluzicki, Christina M; Hugo, Audra; Galindez, Laura K; Sheaffer, Heather; Fox, Kevin R

    2017-03-01

    This article reports on the development, implementation, and evaluation of an integrative clinical oncology massage program for patients undergoing chemotherapy for breast cancer in a large academic medical center. We describe the development and implementation of an oncology massage program embedded into chemoinfusion suites. We used deidentified program evaluation data to identify specific reasons individuals refuse massage and to evaluate the immediate impact of massage treatments on patient-reported outcomes using a modified version of the Distress Thermometer delivered via iPad. We analyzed premassage and postmassage data from the Distress Thermometer using paired t test and derived qualitative data from participants who provided written feedback on their massage experiences. Of the 1,090 massages offered, 692 (63%) were accepted. We observed a significant decrease in self-reported anxiety (from 3.9 to 1.7), nausea (from 2.5 to 1.2), pain (from 3.3 to 1.9), and fatigue (from 4.8 to 3.0) premassage and postmassage, respectively (all P massage, and 649 (94%) would recommend it to another patient undergoing treatment. Spontaneous patient responses overwhelmingly endorsed the massage as relaxing. No adverse events were reported. Among the 398 patients (36%) who declined a massage, top reasons were time concerns and lack of interest. A clinical oncology massage program can be safely and effectively integrated into chemoinfusion units to provide symptom control for patients with breast cancer. This integrative approach overcomes patient-level barriers of cost, time, and travel, and addresses the institutional-level barrier of space.

  1. Factors Influencing Learning Environments in an Integrated Experiential Program

    Science.gov (United States)

    Koci, Peter

    The research conducted for this dissertation examined the learning environment of a specific high school program that delivered the explicit curriculum through an integrated experiential manner, which utilized field and outdoor experiences. The program ran over one semester (five months) and it integrated the grade 10 British Columbian curriculum in five subjects. A mixed methods approach was employed to identify the students' perceptions and provide richer descriptions of their experiences related to their unique learning environment. Quantitative instruments were used to assess changes in students' perspectives of their learning environment, as well as other supporting factors including students' mindfulness, and behaviours towards the environment. Qualitative data collection included observations, open-ended questions, and impromptu interviews with the teacher. The qualitative data describe the factors and processes that influenced the learning environment and give a richer, deeper interpretation which complements the quantitative findings. The research results showed positive scores on all the quantitative measures conducted, and the qualitative data provided further insight into descriptions of learning environment constructs that the students perceived as most important. A major finding was that the group cohesion measure was perceived by students as the most important attribute of their preferred learning environment. A flow chart was developed to help the researcher conceptualize how the learning environment, learning process, and outcomes relate to one another in the studied program. This research attempts to explain through the consideration of this case study: how learning environments can influence behavioural change and how an interconnectedness among several factors in the learning process is influenced by the type of learning environment facilitated. Considerably more research is needed in this area to understand fully the complexity learning

  2. Exploration of Genetic Programming Optimal Parameters for Feature Extraction from Remote Sensed Imagery

    Science.gov (United States)

    Gao, P.; Shetty, S.; Momm, H. G.

    2014-11-01

    Evolutionary computation is used for improved information extraction from high-resolution satellite imagery. The utilization of evolutionary computation is based on stochastic selection of input parameters often defined in a trial-and-error approach. However, exploration of optimal input parameters can yield improved candidate solutions while requiring reduced computation resources. In this study, the design and implementation of a system that investigates the optimal input parameters was researched in the problem of feature extraction from remotely sensed imagery. The two primary assessment criteria were the highest fitness value and the overall computational time. The parameters explored include the population size and the percentage and order of mutation and crossover. The proposed system has two major subsystems; (i) data preparation: the generation of random candidate solutions; and (ii) data processing: evolutionary process based on genetic programming, which is used to spectrally distinguish the features of interest from the remaining image background of remote sensed imagery. The results demonstrate that the optimal generation number is around 1500, the optimal percentage of mutation and crossover ranges from 35% to 40% and 5% to 0%, respectively. Based on our findings the sequence that yielded better results was mutation over crossover. These findings are conducive to improving the efficacy of utilizing genetic programming for feature extraction from remotely sensed imagery.

  3. Integrated care programs for patients with psychological comorbidity : A systematic review and meta-analysis

    NARCIS (Netherlands)

    Lemmens, Lidwien C.; Molema, C.C. M.; Versnel, Nathalie; Baan, C.A.; de Bruin, Simone R.

    2015-01-01

    Objective Presently, little is known about the characteristics and impact of integrated care programs for patients with psychological comorbidity. The aim was to provide an overview of these integrated care programs and their effectiveness. Methods Systematic literature review including papers

  4. Integrated flexible manufacturing program for manufacturing automation and rapid prototyping

    Science.gov (United States)

    Brooks, S. L.; Brown, C. W.; King, M. S.; Simons, W. R.; Zimmerman, J. J.

    1993-01-01

    The Kansas City Division of Allied Signal Inc., as part of the Integrated Flexible Manufacturing Program (IFMP), is developing an integrated manufacturing environment. Several systems are being developed to produce standards and automation tools for specific activities within the manufacturing environment. The Advanced Manufacturing Development System (AMDS) is concentrating on information standards (STEP) and product data transfer; the Expert Cut Planner system (XCUT) is concentrating on machining operation process planning standards and automation capabilities; the Advanced Numerical Control system (ANC) is concentrating on NC data preparation standards and NC data generation tools; the Inspection Planning and Programming Expert system (IPPEX) is concentrating on inspection process planning, coordinate measuring machine (CMM) inspection standards and CMM part program generation tools; and the Intelligent Scheduling and Planning System (ISAPS) is concentrating on planning and scheduling tools for a flexible manufacturing system environment. All of these projects are working together to address information exchange, standardization, and information sharing to support rapid prototyping in a Flexible Manufacturing System (FMS) environment.

  5. Integrated techniques to evaluate the features of sedimentary rocks of archaeological areas of Sicily

    Directory of Open Access Journals (Sweden)

    Maria Brai

    2004-02-01

    Full Text Available Sicily includes a great variety of lithologies, giving a high complexity to the geologic landscape. Their prevalent lithology is sedimentary. It is well known that rocks of sedimentary origin, compared with metamorphic and volcanic deposits, can be relatively soft and hence fairly easy to model. Nevertheless, this workability advantage is a drawback for Cultural Heritage applications. In fact, these materials show a high porosity, with pore-size distributions that lead to deterioration through absorption of water. In this paper, several sedimentary rocks used in historical Cultural Heritage items of Sicily, from "Magna Graecia" to nowadays, are classified for mineralogical features, chemical composition, and for porosity. Particularly, some samples collected in quarries relevant to the archaeological sites of 41 Agrigento, Segesta and Selinunte will be considered and characterized using integrated techniques (XRD, XRF, NMR and CT. Data on samples obtained in laboratory will be compared with the relevant values measured in situ on monuments of historical-cultural interest of the quoted archaeological places.

  6. Residential immersive life skills programs for youth with disabilities: service providers' perceptions of experiential benefits and key program features.

    Science.gov (United States)

    King, Gillian; McPherson, Amy; Kingsnorth, Shauna; Stewart, Debra; Glencross-Eimantas, Tanya; Gorter, Jan Willem; Jones-Galley, Kimberlea; Morrison, Andrea; Isihi, Ana Maria

    2015-01-01

    The objective was to determine service providers' perceptions of the experiential benefits of residential immersive life skills (RILS) programs for youth with disabilities, along with important program features. Thirty-seven service providers from three RILS programs took part in qualitative interviews. Themes were derived using a phenomenological approach. There were perceived benefits for youth, and also for parents and service providers. Study themes concerned the process of youth empowerment, life-changing experiences for youth and parents, and changed service provider views affecting practice. Youth changes were attributed to the residential group format and afforded opportunities, which included being away from home, navigating public transportation, directing attendant services, and sharing intense learning and social experiences with peers. Youth were seen to experience important personal changes in life skills, self-confidence, self-understandings, and self-advocacy. Perceived benefits for parents included realizations concerning their child's abilities and new hope for the future. Service providers indicated changes in their knowledge, perspectives, and approach to practice. The findings suggest that life skills programs should be intentionally designed to provide challenging experiential opportunities that motivate youth to engage in new life directions by providing new insights, self-realizations, and positive yet realistic views of the future. Service providers indicated the importance of challenging, real-world experiential opportunities that provide youth with disabilities with new insights, self-realizations, and positive yet realistic views of the future. Important experiential opportunities for youth included being away from home, navigating public transportation, directing attendant care, and sharing intense learning and social experiences with peers. The findings provide preliminary qualitative evidence that life skills programs should be

  7. INTEGRATION OPPORTUNITIES OF MIGRANTS, WITH ESPECIAL REGARDS TO SENSITIZATION PROGRAMS

    Directory of Open Access Journals (Sweden)

    Krisztina DAJNOKI

    2017-06-01

    Full Text Available As a result of the migration wave appearing in summer 2015, the issue of immigrant integration has more often become conspicuous. Although a significant decline has been recorded in the number of immigrants, social-economic-labor market integration is still a challenge for experts and a task to be resolved. In our opinion, the key to the success of migration strategies and integration-aimed programs depends on the attitude and awareness of society (public opinion and – on the organizational level – the manager and future colleagues as well as on the organizational culture and the approach of a proper human resource expert. Besides adequate information, the recognition of international ‘best practices’ and the adaptation of operational diversity-management, one of the possible methods of facilitating integration is the utilization of sensitization trainings. The article introduces partial results of a questionnaire survey involving 220 employees with respect to attributes associated with migrants and emphasizing the peculiarity and significance of sensitization trainings.

  8. Integrating medical simulation programs into the Turkish undergraduate medical curriculum

    Directory of Open Access Journals (Sweden)

    Kitapçıoğlu D

    2016-01-01

    Full Text Available Dilek Kitapçıoğlu, Mehmet Emin Aksoy Medical Education Department, Faculty of Medicine, Acibadem University, CASE - Center of Advanced Simulation and Education, Istanbul, TurkeyThe letter by Ah-kee and Khan1 arguing that a mandatory year for studying leadership management within an already overcrowded undergraduate curriculum is not realistic and feasible drew our attention. We strongly support this idea because of the difficulties we met during integration of simulation programs into the undergraduate curriculum in Turkey.View the original paper by Ah-kee and Khan.

  9. The integration of an educational program into a treatment facility.

    Science.gov (United States)

    Schuckit, M A; Berger, F

    1989-02-01

    This paper reviews the integration of an active teaching program into a busy treatment facility. All first and second year medical students at the University of California, San Diego take part in a series of didactic lectures and small group discussions, while third and fourth year students have the opportunity of joining a treatment team for 4 to 6 weeks. All psychiatric residents spend a minimum of 8 weeks working on the unit, and one fourth year resident is chosen to work with the staff for a year. The interactions between treatment teams and students in various stages of development help maximize enthusiasm and the commitment to the best patient care possible.

  10. Structural Integrity Program for INTEC Calcined Solids Storage Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey Bryant

    2008-08-30

    This report documents the activities of the structural integrity program at the Idaho Nuclear Technology and Engineering Center relevant to the high-level waste Calcined Solids Storage Facilities and associated equipment, as required by DOE M 435.1-1, 'Radioactive Waste Management Manual'. Based on the evaluation documented in this report, the Calcined Solids Storage Facilities are not leaking and are structurally sound for continued service. Recommendations are provided for continued monitoring of the Calcined Solids Storage Facilities.

  11. Brain responses to language-relevant musical features in adolescent cochlear implant users before and after an intensive music training program

    DEFF Research Database (Denmark)

    Petersen, Bjørn; Weed, Ethan; Hansen, Mads

    Brain responses to language-relevant musical features in adolescent cochlear implant users before and after an intensive music training program Petersen B.1,2, Weed E.1,3, Hansen M.1,4, Sørensen S.D.3 , Sandmann P.5 , Vuust P.1,2 1Center of Functionally Integrative Neuroscience, Aarhus University...... musical training. The finding points toward the possibility of improving appreciation of music in general for adolescent CI users, and using music as a motivating element in speech therapy programs....

  12. Aeronautics Research Mission Directorate Integrated Systems Research Program (ISRP) and UAS Integration in the NAS Project

    Science.gov (United States)

    Wolfe, Jean

    2010-01-01

    Program Goal: Conduct research at an integrated system-level on promising concepts and technologies and explore, assess, or demonstrate the benefits in a relevant environment.Criteria for selection of projects for Integrated Systems Research: a) Technology has attained enough maturity in the foundational research program that they merit more in-depth evaluation at an integrated system level in a relevant environment. b) Technologies which systems analysis indicates have the most potential for contributing to the simultaneous attainment of goals. c) Technologies identified through stakeholder input as having potential for simultaneous attainment of goals. d) Research not being done by other government agencies and appropriate for NASA to conduct. e) Budget augmentation. Environmentally Responsible Aviation (ERA) Project Explore and assess new vehicle concepts and enabling technologies through system-level experimentation to simultaneously reduce fuel burn, noise, and emissions Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project Contribute capabilities that reduce technical barriers related to the safety and operational challenges associated with enabling routine UAS access to the NAS Innovative Concepts for Green Aviation (ICGA) Project Spur innovation by offering research opportunities to the broader aeronautics community through peer-reviewed proposals, with a focus on making aviation more eco-friendly. Establish incentive prizes similar to the Centennial Challenges and sponsor innovation demonstrations of selected technologies that show promise of reducing aviation s impact on the environment

  13. The features of teaching methods of programming in the system of supplementary education in informatics and ICT

    Directory of Open Access Journals (Sweden)

    Наталья Геннадьевна Саблукова

    2010-06-01

    Full Text Available The model of formation of the rational contents of teaching to programming in described in the article in view of specificity of supplementary education and features of visual surroundings of programming. The realization of structure of the contents of training to programming is written stage by stage.

  14. 49 CFR 192.911 - What are the elements of an integrity management program?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false What are the elements of an integrity management... Transmission Pipeline Integrity Management § 192.911 What are the elements of an integrity management program? An operator's initial integrity management program begins with a framework (see § 192.907) and...

  15. Integrated research training program of excellence in radiochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Lapi, Suzanne [Washington Univ., St. Louis, MO (United States)

    2015-09-18

    The overall goal of this “Integrated Research Training Program of Excellence in Radiochemistry” is to provide a rich and deep research experience in state-of-the-art radiochemistry and in the fundamentals of radioisotopic labeling and tracer methodology to develop researchers who are capable of meeting the challenges of designing and preparing radiotracers of broad applicability for monitoring and imaging diverse biological systems and environmental processes. This program was based in the Departments of Radiology and Radiation Oncology at Washington University Medical School and the Department of Chemistry at the University of Illinois at Urbana Champaign, and it was initially directed by Professor Michael J. Welch as Principal Investigator. After his passing in 2012, the program was led by Professor Suzanne E. Lapi. Programmatic content and participant progress was overseen by an Internal Advisory Committee of senior investigators consisting of the PIs, Professor Mach from the Department of Radiology at Washington University and Professor John A. Katzenellenbogen of the Department of Chemistry at the University of Illinois. A small External Advisory Committee to give overall program guidance was also constituted of experts in radiolabeled compounds and in their applications in environmental and plant science.

  16. Integrated Risk Management Within NASA Programs/Projects

    Science.gov (United States)

    Connley, Warren; Rad, Adrian; Botzum, Stephen

    2004-01-01

    As NASA Project Risk Management activities continue to evolve, the need to successfully integrate risk management processes across the life cycle, between functional disciplines, stakeholders, various management policies, and within cost, schedule and performance requirements/constraints become more evident and important. Today's programs and projects are complex undertakings that include a myriad of processes, tools, techniques, management arrangements and other variables all of which must function together in order to achieve mission success. The perception and impact of risk may vary significantly among stakeholders and may influence decisions that may have unintended consequences on the project during a future phase of the life cycle. In these cases, risks may be unintentionally and/or arbitrarily transferred to others without the benefit of a comprehensive systemic risk assessment. Integrating risk across people, processes, and project requirements/constraints serves to enhance decisions, strengthen communication pathways, and reinforce the ability of the project team to identify and manage risks across the broad spectrum of project management responsibilities. The ability to identify risks in all areas of project management increases the likelihood a project will identify significant issues before they become problems and allows projects to make effective and efficient use of shrinking resources. By getting a total team integrated risk effort, applying a disciplined and rigorous process, along with understanding project requirements/constraints provides the opportunity for more effective risk management. Applying an integrated approach to risk management makes it possible to do a better job at balancing safety, cost, schedule, operational performance and other elements of risk. This paper will examine how people, processes, and project requirements/constraints can be integrated across the project lifecycle for better risk management and ultimately improve the

  17. Mission X in Japan, an Education Outreach Program Featuring Astronautical Specialties and Knowledge

    Science.gov (United States)

    Niihori, Maki; Yamada, Shin; Matsuo, Tomoaki; Nakao, Reiko; Nakazawa, Takashi; Kamiyama, Yoshito; Takeoka, Hajime; Matsumoto, Akiko; Ohshima, Hiroshi; Mukai, Chiaki

    In the science field, disseminating new information to the public is becoming increasingly important, since it can aid a deeper understanding of scientific significance and increase the number of future scientists. As part of our activities, we at the Japan Aerospace Exploration Agency (JAXA) Space Biomedical Research Office, started work to focus on education outreach featuring space biomedical research. In 2010, we launched the Mission X education program in Japan, named after “Mission X: Train Like an Astronaut” (hereinafter called “Mission X”), mainly led by NASA and European Space Agency (ESA). Mission X is an international public outreach program designed to encourage proper nutrition and exercise and teaching young people to live and eat like astronauts. We adopted Mission X's standpoint, and modified the program based on the originals to suit Japanese culture and the students' grade. Using astronauts as examples, this mission can motivate and educate students to instill and adopt good nutrition and physical fitness as life-long practices.Here we introduce our pilot mission of the “Mission X in Japan” education program, which was held in early 2011. We are continuing the education/public outreach to promote the public understanding of science and contribute to science education through lectures on astronautical specialties and knowledge.

  18. Immunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies.

    Science.gov (United States)

    Brito, Rory C F; Guimarães, Frederico G; Velloso, João P L; Corrêa-Oliveira, Rodrigo; Ruiz, Jeronimo C; Reis, Alexandre B; Resende, Daniela M

    2017-02-10

    Leishmaniasis is a wide-spectrum disease caused by parasites from Leishmania genus. There is no human vaccine available and it is considered by many studies as apotential effective tool for disease control. To discover novel antigens, computational programs have been used in reverse vaccinology strategies. In this work, we developed a validation antigen approach that integrates prediction of B and T cell epitopes, analysis of Protein-Protein Interaction (PPI) networks and metabolic pathways. We selected twenty candidate proteins from Leishmania tested in murine model, with experimental outcome published in the literature. The predictions for CD4⁺ and CD8⁺ T cell epitopes were correlated with protection in experimental outcomes. We also mapped immunogenic proteins on PPI networks in order to find Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways associated with them. Our results suggest that non-protective antigens have lowest frequency of predicted T CD4⁺ and T CD8⁺ epitopes, compared with protective ones. T CD4⁺ and T CD8⁺ cells are more related to leishmaniasis protection in experimental outcomes than B cell predicted epitopes. Considering KEGG analysis, the proteins considered protective are connected to nodes with few pathways, including those associated with ribosome biosynthesis and purine metabolism.

  19. Integrating Research and Education in NSF's Office of Polar Programs

    Science.gov (United States)

    Wharton, R. A.; Crain, R. D.

    2003-12-01

    The National Science Foundation invests in activities that integrate research and education, and that develop reward systems to support teaching, mentoring and outreach. Effective integration of research and education at all levels can infuse learning with the excitement of discovery. It can also ensure that the findings and methods of research are quickly and effectively communicated in a broader context and to a larger audience. This strategy is vital to the accomplishment of NSF's strategic goals of ensuring a world-class science and engineering workforce, new knowledge across the frontiers of science and engineering, and the tools to get the job done efficiently and effectively. The NSF's Office of Polar Programs sponsors educational projects at all levels of learning, making full use of the variety of disciplinary and interdisciplinary studies in the polar regions to attract and invigorate students. An array of efforts from the Arctic and Antarctic scientific communities link research activities with education. There has been an advance from the beneficial but isolated impacts of individual researcher visits to K-12 classrooms to large-scale developments, such as field research experiences for teachers and undergraduate students, online sharing of polar field experiences with rural classrooms, the institution of interdisciplinary graduate research programs through NSF initiatives, and opportunities for minority and underrepresented groups in polar sciences. The NSF's criterion for evaluating proposals based upon the broader impacts of the research activity has strengthened efforts to link research and education, resulting in partnerships and innovations that infuse research into education from kindergarten through postdoctoral studies and reaching out to the general public. In addition, the Office of Polar Programs partners with other directorates at NSF to broaden OPP's efforts and benefit from resources and experience in the Education and Human Resources

  20. How Perception Guides Action: Figure-Ground Segmentation Modulates Integration of Context Features into S-R Episodes

    Science.gov (United States)

    Frings, Christian; Rothermund, Klaus

    2017-01-01

    Perception and action are closely related. Responses are assumed to be represented in terms of their perceptual effects, allowing direct links between action and perception. In this regard, the integration of features of stimuli (S) and responses (R) into S-R bindings is a key mechanism for action control. Previous research focused on the…

  1. New features of the National Cholesterol Education Program Adult Treatment Panel III lipid-lowering guidelines.

    Science.gov (United States)

    Brewer, H Bryan

    2003-04-01

    The National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) guidelines for lipid-lowering therapy to reduce coronary heart disease (CHD) risk contain a number of features that distinguish them from the previous ATP guidelines. These new features include modifications in lipid/lipoprotein levels considered optimal, abnormal, or reflective of risk; increased focus on primary prevention through use of Framingham risk scoring to define risk in persons with multiple lipid/nonlipid risk factors; and increased focus on the association of the metabolic syndrome with CHD risk. The introduction of the category of CHD risk equivalents-including persons with atherosclerotic disease, diabetes, or 10-year CHD risk > 20% based on Framingham scoring-results in an increase over previous guidelines in the proportion of patients categorized as being at high risk and therefore eligible for more intensive low-density lipoprotein cholesterol (LDL-C)-lowering therapy. Use of the new secondary therapeutic target of non-high-density lipoprotein cholesterol should improve management of lipid risk factors in patients who have elevated triglyceride levels after LDL-C goals have been met. These new features of the NCEP ATP III guidelines should improve identification and treatment of patients with dyslipidemias associated with CHD risk.

  2. Integrative Reiki for cancer patients: a program evaluation.

    Science.gov (United States)

    Fleisher, Kimberly A; Mackenzie, Elizabeth R; Frankel, Eitan S; Seluzicki, Christina; Casarett, David; Mao, Jun J

    2014-01-01

    This mixed methods study sought to evaluate the outcomes of an integrative Reiki volunteer program in an academic medical oncology center setting. We used de-identified program evaluation data to perform both quantitative and qualitative analyses of participants' experiences of Reiki sessions. The quantitative data were collected pre- and postsession using a modified version of the distress thermometer. The pre- and postsession data from the distress assessment were analyzed using a paired Student's : test. The qualitative data were derived from written responses to open-ended questions asked after each Reiki session and were analyzed for key words and recurring themes. Of the 213 pre-post surveys of first-time sessions in the evaluation period, we observed a more than 50% decrease in self-reported distress (from 3.80 to 1.55), anxiety (from 4.05 to 1.44), depression (from 2.54 to 1.10), pain (from 2.58 to 1.21), and fatigue (from 4.80 to 2.30) with P Reiki, we found 176 (82.6%) of participants liked the Reiki session, 176 (82.6%) found the Reiki session helpful, 157 (73.7%) plan to continue using Reiki, and 175 (82.2%) would recommend Reiki to others. Qualitative analyses found that individuals reported that Reiki induced relaxation and enhanced spiritual well-being. An integrative Reiki volunteer program shows promise as a component of supportive care for cancer patients. More research is needed to evaluate and understand the impact that Reiki may have for patients, caregivers, and staff whose lives have been affected by cancer.

  3. Brazilian Air Force aircraft structural integrity program: An overview

    Directory of Open Access Journals (Sweden)

    Alberto W. S. Mello Junior

    2009-01-01

    Full Text Available This paper presents an overview of the activities developed by the Structural Integrity Group at the Institute of Aeronautics and Space - IAE, Brazil, as well as the status of ongoing work related to the life extension program for aircraft operated by the Brazilian Air Force BAF. The first BAF-operated airplane to undergo a DTA-based life extension was the F-5 fighter, in the mid 1990s. From 1998 to 2001, BAF worked on a life extension project for the BAF AT- 26 Xavante trainer. All analysis and tests were performed at IAE. The fatigue critical locations (FCLs were presumed based upon structural design and maintenance data and also from exchange of technical information with other users of the airplane around the world. Following that work, BAF started in 2002 the extension of the operational life of the BAF T-25 “Universal”. The T-25 is the basic training airplane used by AFA - The Brazilian Air Force Academy. This airplane was also designed under the “safe-life” concept. As the T-25 fleet approached its service life limit, the Brazilian Air Force was questioning whether it could be kept in flight safely. The answer came through an extensive Damage Tolerance Analysis (DTA program, briefly described in this paper. The current work on aircraft structural integrity is being performed for the BAF F-5 E/F that underwent an avionics and weapons system upgrade. Along with the increase in weight, new configurations and mission profiles were established. Again, a DTA program was proposed to be carried out in order to establish the reliability of the upgraded F-5 fleet. As a result of all the work described, the BAF has not reported any accident due to structural failure on aircraft submitted to Damage Tolerance Analysis.

  4. A free tool integrating GIS features and workflows to evaluate sediment connectivity in alpine catchments

    Science.gov (United States)

    Crema, Stefano; Schenato, Luca; Goldin, Beatrice; Marchi, Lorenzo; Cavalli, Marco

    2014-05-01

    The increased interest in sediment connectivity has brought the geomorphologists' community to focus on sediment fluxes as a key process (Cavalli et al., 2013; Heckmann and Schwanghart, 2013). The challenge of dealing with erosion-related processes in alpine catchments is of primary relevance for different fields of investigations and applications, including, but not limited to natural hazards, hydraulic structures design, ecology and stream restoration. The present work focuses on the development of a free tool for sediment connectivity assessment as described in Cavalli et al. (2013), introducing some novel improvements. The choice of going for a free software is motivated by the need of widening the access and improving participation beyond the restrictions on algorithms customization, typical of commercial software. A couple of features further enhance the tool: being completely free and adopting a user-friendly interface, its target audience includes researchers and stakeholders (e.g., local managers and civil protection authorities in charge of planning the priorities of intervention in the territory), being written in Python programming language, it can benefit from optimized algorithms for high-resolution DEMs (Digital Elevation Models) handling and for propagation workflows implementation; these two factors make the tool computationally competitive with the most recent commercial GIS products. The overall goal of this tool is supporting the analysis of sediment connectivity, facing the challenge of widening, as much as possible, the users' community among scientists and stakeholders. This aspect is crucial, as future improvement of this tool will benefit of feedbacks from users in order to improve the quantitative assessment of sediment connectivity as a major input information for the optimal management of mountain areas. References: Cavalli, M., Trevisani, S., Comiti, F., Marchi, L., 2013. Geomorphometric assessment of spatial sediment connectivity in

  5. Sequential Modulations in a Combined Horizontal and Vertical Simon Task: Is There ERP Evidence for Feature Integration Effects?

    Science.gov (United States)

    Hoppe, Katharina; Küper, Kristina; Wascher, Edmund

    2017-01-01

    In the Simon task, participants respond faster when the task-irrelevant stimulus position and the response position are corresponding, for example on the same side, compared to when they have a non-corresponding relation. Interestingly, this Simon effect is reduced after non-corresponding trials. Such sequential effects can be explained in terms of a more focused processing of the relevant stimulus dimension due to increased cognitive control, which transfers from the previous non-corresponding trial (conflict adaptation effects). Alternatively, sequential modulations of the Simon effect can also be due to the degree of trial-to-trial repetitions and alternations of task features, which is confounded with the correspondence sequence (feature integration effects). In the present study, we used a spatially two-dimensional Simon task with vertical response keys to examine the contribution of adaptive cognitive control and feature integration processes to the sequential modulation of the Simon effect. The two-dimensional Simon task creates correspondences in the vertical as well as in the horizontal dimension. A trial-by-trial alternation of the spatial dimension, for example from a vertical to a horizontal stimulus presentation, generates a subset containing no complete repetitions of task features, but only complete alternations and partial repetitions, which are equally distributed over all correspondence sequences. In line with the assumed feature integration effects, we found sequential modulations of the Simon effect only when the spatial dimension repeated. At least for the horizontal dimension, this pattern was confirmed by the parietal P3b, an event-related potential that is assumed to reflect stimulus-response link processes. Contrary to conflict adaptation effects, cognitive control, measured by the fronto-central N2 component of the EEG, was not sequentially modulated. Overall, our data provide behavioral as well as electrophysiological evidence for feature

  6. Evaluation of Integrated Child Development Services program in Gujarat, India.

    Science.gov (United States)

    Chudasama, Rajesh K; Kadri, A M; Verma, Pramod B; Patel, Umed V; Joshi, Nirav; Zalavadiya, Dipesh; Bhola, Chirag

    2014-09-01

    To evaluate Integrated Child Development Services (ICDS) program in terms of infrastructure of Anganwadi centers, inputs, process, coverage and utilization of services, and issues related to program operation in twelve districts of Gujarat, India. Facility (Anganwadi) based study. Twelve districts of Gujarat, India (April 1, 2012 to March 31, 2013). ICDS service providers (60 Anganwadi workers from 46 rural and 14 urban Anganwadi centers) and their beneficiaries. Coverage of supplementary nutrition, pre-school education, immunization and referral services. Supplementary nutrition coverage was reported in 48.3% in children. Interruption in supply of supplementary nutrition during last six months was reported in 61.7% Anganwadi centers. Only 20% centers reported 100% pre-school education coverage among children. Immunization of all children was recorded in only 10% Anganwadi centers, while in 76.7% centers, no such records were available. Regular health checkup of beneficiaries was done in 30% centers. Referral slips were available in 18.3% Anganwadi centers and referral of sick children was done from only 8.3% centers. There are program gaps in coverage of supplementary nutrition in children, its regular supply to the beneficiaries, in pre-school activities coverage, recording of immunization, and regular health check-up of beneficiaries and referral of sick children.

  7. An examination of program integrity and recidivism of a cognitive-behavioral program for incarcerated youth in The Netherlands

    NARCIS (Netherlands)

    Helmond, P.; Overbeek, G.; Brugman, D.

    2015-01-01

    The present study examined whether the cognitive behavioral program EQUIP for incarcerated youth would reduce recidivism and whether higher levels of program integrity - the extent to which a program is implemented as intended - would strengthen the effectiveness of EQUIP on recidivism. Program

  8. The Anne Frank Haven: A case of an alternative educational program in an integrative Kibbutz setting

    Science.gov (United States)

    Ben-Peretz, Miriam; Giladi, Moshe; Dror, Yuval

    1992-01-01

    The essential features of the programme of the Anne Frank Haven are the complete integration of children from low SES and different cultural backgrounds with Kibbutz children; a holistic approach to education; and the involvement of the whole community in an "open" residential school. After 33 years, it is argued that the experiment has proved successful in absorbing city-born youth in the Kibbutz, enabling at-risk populations to reach significant academic achievements, and ensuring their continued participation in the dominant culture. The basic integration model consists of "layers" of concentric circles, in dynamic interaction. The innermost circle is the class, the learning community. The Kibbutz community and the foster parents form a supportive, enveloping circle, which enables students to become part of the outer community and to intervene in it. A kind of meta-environment, the inter-Kibbutz partnership and the Israeli educational system, influence the program through decision making and guidance. Some of the principles of the Haven — integration, community involvement, a year's induction for all new students, and open residential settings — could be useful for cultures and societies outside the Kibbutz. The real "secret" of success of an alternative educational program is the dedicated, motivated and highly trained staff.

  9. Integrated Data Collection Analysis (IDCA) Program — Ammonium Nitrate

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Phillips, Jason J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shelley, Timothy J. [Bureau of Alcohol, Tobacco and Firearms, Redstone Arsenal, AL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-05-17

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of ammonium nitrate (AN). AN was tested, in most cases, as both received from manufacturer and dried/sieved. The participants found the AN to be: 1) insensitive in Type 12A impact testing (although with a wide range of values), 2) completely insensitive in BAM friction testing, 3) less sensitive than the RDX standard in ABL friction testing, 4) less sensitive than RDX in ABL ESD testing, and 5) less sensitive than RDX and PETN in DSC thermal analyses.

  10. Steam generator tube integrity program. Phase I report. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Alzheimer, J.M.; Clark, R.A.; Morris, C.J.; Vagins, M.

    1979-09-01

    The results are presented of the pressure tests performed as part of Phase I of the Steam Generator Tube Integrity (SGTI) program at Battelle Pacific Northwest Laboratory. These tests were performed to establish margin-to-failure predictions for mechanically defected Pressurized Water Reactor (PWR) steam generator tubing under operating and accident conditions. Defect geometries tested were selected because they simulate known or expected defects in PWR steam generators. These defect geometries are Electric Discharge Machining (EDM) slots, elliptical wastage, elliptical wastage plus through-wall slot, uniform thinning, denting, denting plus uniform thinning, and denting plus elliptical wastage. All defects were placed in tubing representative of that currently used in PWR steam generators.

  11. Residual-energy-applications program: support and integration report

    Energy Technology Data Exchange (ETDEWEB)

    1980-11-01

    The proposed government-owned EAST Facility at the Savannah River Plant in Aiken, South Carolina, would provide capabilities for development and confidence testing of industrial heat pumps, high temperature bottoming cycles, low temperature Rankine cycle power generation systems, and absorption chillers. This work is one component of the Residual Energy Applications Program (REAP). Other documents provide initial considerations concerning the heat pump and power generation systems to be tested at EAST, policy, objectives and guidelines for operation of the facility, a preliminary conceptual design, and environmental data. This report describes support and integration activities that were performed during the contract year. The various elements that impact on the EAST Facility are discussed and an assessment of the EAST Facility mission is given. The report concludes with proposed milestones, schedules, and costs for design, construction, and operation of the facility.

  12. Lessons from the National Mental Health Integration Program.

    Science.gov (United States)

    Eagar, Kathy; Pirkis, Jane E; Owen, Alan; Burgess, Philip M; Posner, Natasha; Perkins, David A

    2005-05-01

    Three projects were funded under the national Mental Health Integration Program (MHIP) in 1999, each of which employed a different model aimed at improving linkages between disparate parts of the mental health system. A national evaluation framework guided local evaluations of these projects, and this paper presents a synthesis of the findings. For providers, the projects improved working relationships, created learning opportunities and increased referral and shared care opportunities. For consumers and carers, the projects resulted in a greater range of options and increased continuity of care. For the wider system, the projects achieved significant structural and cultural change. Cost-wise, there were no increases in expenditure, and even some reductions. Many of the lessons from the projects (and their evaluations) may be generalised to other mental health settings and beyond.

  13. Programming of adaptive repair process chains using repair features and function blocks

    Directory of Open Access Journals (Sweden)

    Gunter Spöcker

    2016-01-01

    Full Text Available The current trends of product customization and repair of high value parts with individual defects demand automation and a high degree of flexibility of the involved manufacturing process chains. To determine the corresponding requirements this paper gives an overview of manufacturing process chains by distinguishing between horizontal and vertical process chains. The established way of modeling and programming processes with CAx systems and existing approaches is shown. Furthermore, the different types of possible adaptions of a manufacturing process chain are shown and considered as a cascaded control loop. Following this it is discussed which key requirements of repair process chains are unresolved by existing approaches. To overcome the deficits this paper introduces repair features which comprise the idea of geometric features and defines analytical auxiliary geometries based on the measurement input data. This meets challenges normally caused by working directly on reconstructed geometries in the form of triangulated surfaces which are prone to artifacts. Embedded into function blocks, this allows the use of traditional approaches for manufacturing process chains to be applied to adaptive repair process chains.

  14. Integrated Data Collection Analysis (IDCA) Program - SSST Testing Methods

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Whinnery, LeRoy L. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Phillips, Jason J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Shelley, Timothy J. [Bureau of Alcohol, Tobacco and Firearms (ATF), Huntsville, AL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-03-25

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the methods used for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis during the IDCA program. These methods changed throughout the Proficiency Test and the reasons for these changes are documented in this report. The most significant modifications in standard testing methods are: 1) including one specified sandpaper in impact testing among all the participants, 2) diversifying liquid test methods for selected participants, and 3) including sealed sample holders for thermal testing by at least one participant. This effort, funded by the Department of Homeland Security (DHS), is putting the issues of safe handling of these materials in perspective with standard military explosives. The study is adding SSST testing results for a broad suite of different HMEs to the literature. Ultimately the study will suggest new guidelines and methods and possibly establish the SSST testing accuracies needed to develop safe handling practices for HMEs. Each participating testing laboratory uses identical test materials and preparation methods wherever possible. The testing performers involved are Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Indian Head Division, Naval Surface Warfare Center, (NSWC IHD), Sandia National Laboratories (SNL), and Air Force Research Laboratory (AFRL/RXQL). These tests are conducted as a proficiency study in order to establish some consistency in test protocols, procedures, and experiments and to compare results when these testing variables cannot be made consistent.

  15. [Adolescent social integration through the "Cuidar cuidando" program].

    Science.gov (United States)

    Vasen, Juan; Massei, Hugo

    2006-01-01

    The "Care Caring program" is a device of social reinsertion, carried out by a multidisciplinary and a multi-institutional practice of more than fifteen years. Those who sustain it, have always presented the necessity of articulating the cure with social reinsertion, therefore the purpose of the Program itself is not only to favour a clinical psychiatric recovery, but also to prompt changes in the manner of social liaison of the children and youngsters taking part. Animal contact in many way produce therapeutic effects. We describe here those we have seen and discuss the "popular" term zootherapy. After 16 years of non stop activity, more than 500 children and adolescents benefited from this innovative experience. We learned also that without broad social integration policies, the devices of reinsertion are limited in their long term effects. Breaking the differentiation circuit is impossible only with these resources. Working out these difficulties will allow us to answer if it is possible to think of strategies of rehabilitation in psychology and psychiatry for infancy and adolescence using communal resources.

  16. Integrated Healthcare Delivery: A Qualitative Research Approach to Identifying and Harmonizing Perspectives of Integrated Neglected Tropical Disease Programs.

    Directory of Open Access Journals (Sweden)

    Arianna Rubin Means

    2016-10-01

    Full Text Available While some evidence supports the beneficial effects of integrating neglected tropical disease (NTD programs to optimize coverage and reduce costs, there is minimal information regarding when or how to effectively operationalize program integration. The lack of systematic analyses of integration experiences and of integration processes may act as an impediment to achieving more effective NTD programming. We aimed to learn about the experiences of NTD stakeholders and their perceptions of integration.We evaluated differences in the definitions, roles, perceived effectiveness, and implementation experiences of integrated NTD programs among a variety of NTD stakeholder groups, including multilateral organizations, funding partners, implementation partners, national Ministry of Health (MOH teams, district MOH teams, volunteer rural health workers, and community members participating in NTD campaigns. Semi-structured key informant interviews were conducted. Coding of themes involved a mix of applying in-vivo open coding and a priori thematic coding from a start list.In total, 41 interviews were conducted. Salient themes varied by stakeholder, however dominant themes on integration included: significant variations in definitions, differential effectiveness of specific integrated NTD activities, community member perceptions of NTD programs, the influence of funders, perceived facilitators, perceived barriers, and the effects of integration on health system strength. In general, stakeholder groups provided unique perspectives, rather than contrarian points of view, on the same topics. The stakeholders identified more advantages to integration than disadvantages, however there are a number of both unique facilitators and challenges to integration from the perspective of each stakeholder group.Qualitative data suggest several structural, process, and technical opportunities that could be addressed to promote more effective and efficient integrated NTD

  17. Design Features of Product-Integrated PV : An Evaluation of Various Factors under Indoor Irradiance Conditions

    NARCIS (Netherlands)

    Apostolou, G.

    2016-01-01

    This thesis explores the field of product-integrated photovoltaics (PIPV), a term which is used for all types of products that contain solar cells in one or more of their surfaces, aiming at providing power during the product’s use. Product-integrated photovoltaics (PIPV) began to be widely

  18. Integrated Pest Management: A Curriculum for Early Care and Education Programs

    Science.gov (United States)

    California Childcare Health Program, 2011

    2011-01-01

    This "Integrated Pest Management Toolkit for Early Care and Education Programs" presents practical information about using integrated pest management (IPM) to prevent and manage pest problems in early care and education programs. This curriculum will help people in early care and education programs learn how to keep pests out of early…

  19. Artificial Neural Networks and Gene Expression Programing based age estimation using facial features

    Directory of Open Access Journals (Sweden)

    Baddrud Z. Laskar

    2015-10-01

    Full Text Available This work is about estimating human age automatically through analysis of facial images. It has got a lot of real-world applications. Due to prompt advances in the fields of machine vision, facial image processing, and computer graphics, automatic age estimation via faces in computer is one of the dominant topics these days. This is due to widespread real-world applications, in areas of biometrics, security, surveillance, control, forensic art, entertainment, online customer management and support, along with cosmetology. As it is difficult to estimate the exact age, this system is to estimate a certain range of ages. Four sets of classifications have been used to differentiate a person’s data into one of the different age groups. The uniqueness about this study is the usage of two technologies i.e., Artificial Neural Networks (ANN and Gene Expression Programing (GEP to estimate the age and then compare the results. New methodologies like Gene Expression Programing (GEP have been explored here and significant results were found. The dataset has been developed to provide more efficient results by superior preprocessing methods. This proposed approach has been developed, tested and trained using both the methods. A public data set was used to test the system, FG-NET. The quality of the proposed system for age estimation using facial features is shown by broad experiments on the available database of FG-NET.

  20. Initial experience with a risk-sharing in vitro fertilization-embryo transfer program with novel features.

    Science.gov (United States)

    Stassart, Jacques P; Bayless, Romaine B; Casey, Colleen L; Phipps, William R

    2011-06-01

    To describe outcomes of the first 100 consecutive infertility patients participating in a risk-sharing program with uncomplicated eligibility requirements. The program included the costs of FSH-containing gonadotropin preparations and provided a full payment refund if no birth occurred that resulted in a normal infant surviving to an age of 1 month. Retrospective cohort study. Private IVF center. Infertility patientsrisk-sharing program with uncomplicated eligibility requirements are very likely to have a successful pregnancy. Other centers may wish to incorporate some of the described program's features into their own risk-sharing IVF programs. Copyright © 2011. Published by Elsevier Inc.

  1. Fronting Integrated Scientific Web Applications: Design Features and Benefits for Regulatory Environments

    Science.gov (United States)

    Integrated decision support systems for regulatory applications benefit from standardindustry practices such as code reuse, test-driven development, and modularization. Theseapproaches make meeting the federal government’s goals of transparency, efficiency, and quality assurance ...

  2. Features of development of an integral parameter for assessing the capital adequacy of bank

    Directory of Open Access Journals (Sweden)

    Kolesnyk Y.

    2013-01-01

    Full Text Available The article deals with the statistical approaches integral indicator based on multivariate statistical techniques for assessing the capital adequacy of bank. The necessity of using the rating methodology to characterize the efficiency of capital banks.

  3. 76 FR 81015 - Notice of Public Webinar on Implementation of Distribution Integrity Management Programs

    Science.gov (United States)

    2011-12-27

    ... Distribution Integrity Management Programs AGENCY: Pipeline and Hazardous Materials Safety Administration... have prepared and implemented distribution integrity management plans (DIMP) by August 2, 2011. Federal....regulations.gov including any personal information provided. Please see the Privacy Act statement immediately...

  4. Integrating scientific knowledge into large-scale restoration programs: the CALFED Bay-Delta Program experience

    Science.gov (United States)

    Taylor, K.A.; Short, A.

    2009-01-01

    Integrating science into resource management activities is a goal of the CALFED Bay-Delta Program, a multi-agency effort to address water supply reliability, ecological condition, drinking water quality, and levees in the Sacramento-San Joaquin Delta of northern California. Under CALFED, many different strategies were used to integrate science, including interaction between the research and management communities, public dialogues about scientific work, and peer review. This paper explores ways science was (and was not) integrated into CALFED's management actions and decision systems through three narratives describing different patterns of scientific integration and application in CALFED. Though a collaborative process and certain organizational conditions may be necessary for developing new understandings of the system of interest, we find that those factors are not sufficient for translating that knowledge into management actions and decision systems. We suggest that the application of knowledge may be facilitated or hindered by (1) differences in the objectives, approaches, and cultures of scientists operating in the research community and those operating in the management community and (2) other factors external to the collaborative process and organization.

  5. Results of the NASP Ames Integrated Mixing Hypersonic Engine (AIMHYE) Scramjet Test Program

    Science.gov (United States)

    Cavolowsky, John A.; Loomis, Mark P.; Deiwert, George S.

    1995-01-01

    This paper describes the test techniques and results from the National Aerospace Plane Government Work Package 53, the Ames Integrated Mixing Hypersonic Engine (AIMHYE) Scramjet Test program conducted in the NASA Ames 16-Inch Combustion Driven Shock Tunnel. This was a series of near full-scale scramjet combustor tests with the objective to obtain high speed combustor and nozzle data from an engine with injector configurations similar to the NASP E21 and E22a designs. The experimental test approach was to use a large combustor model (80-100% throat height) designed and fabricated for testing in the semi-free jet mode. The conditions tested were similar to the "blue book" conditions at Mach 12, 14, and 16. GWP 53 validated use of large, long test time impulse facilities, specifically the Ames 16-Inch Shock Tunnel, for high Mach number scramjet propulsion testing an integrated test rig (inlet, combustor, and nozzle). Discussion of key features of the test program will include: effects of the 2-D combustor inlet pressure profile; performance of large injectors' fueling system that included nozzlettes, base injection, and film cooling; and heat transfer measurements to the combustor. Significant instrumentation development and application efforts include the following: combustor force balance application for measurement of combustor drag for comparison with integrated point measurements of skin friction; nozzle metric strip for measuring thrust with comparison to integrated pressure measurements; and nonintrusive optical fiber-based diode laser absorption measurements of combustion products for determination of combustor performance. Direct measurements will be reported for specific test article configurations and compared with CFD solutions.

  6. Reconsideration of in-silico siRNA design based on feature selection: a cross-platform data integration perspective.

    Science.gov (United States)

    Liu, Qi; Zhou, Han; Cui, Juan; Cao, Zhiwei; Xu, Ying

    2012-01-01

    RNA interference via exogenous short interference RNAs (siRNA) is increasingly more widely employed as a tool in gene function studies, drug target discovery and disease treatment. Currently there is a strong need for rational siRNA design to achieve more reliable and specific gene silencing; and to keep up with the increasing needs for a wider range of applications. While progress has been made in the ability to design siRNAs with specific targets, we are clearly at an infancy stage towards achieving rational design of siRNAs with high efficacy. Among the many obstacles to overcome, lack of general understanding of what sequence features of siRNAs may affect their silencing efficacy and of large-scale homogeneous data needed to carry out such association analyses represents two challenges. To address these issues, we investigated a feature-selection based in-silico siRNA design from a novel cross-platform data integration perspective. An integration analysis of 4,482 siRNAs from ten meta-datasets was conducted for ranking siRNA features, according to their possible importance to the silencing efficacy of siRNAs across heterogeneous data sources. Our ranking analysis revealed for the first time the most relevant features based on cross-platform experiments, which compares favorably with the traditional in-silico siRNA feature screening based on the small samples of individual platform data. We believe that our feature ranking analysis can offer more creditable suggestions to help improving the design of siRNA with specific silencing targets. Data and scripts are available at http://csbl.bmb.uga.edu/publications/materials/qiliu/siRNA.html.

  7. Revealing metabolite biomarkers for acupuncture treatment by linear programming based feature selection.

    Science.gov (United States)

    Wang, Yong; Wu, Qiao-Feng; Chen, Chen; Wu, Ling-Yun; Yan, Xian-Zhong; Yu, Shu-Guang; Zhang, Xiang-Sun; Liang, Fan-Rong

    2012-01-01

    Acupuncture has been practiced in China for thousands of years as part of the Traditional Chinese Medicine (TCM) and has gradually accepted in western countries as an alternative or complementary treatment. However, the underlying mechanism of acupuncture, especially whether there exists any difference between varies acupoints, remains largely unknown, which hinders its widespread use. In this study, we develop a novel Linear Programming based Feature Selection method (LPFS) to understand the mechanism of acupuncture effect, at molecular level, by revealing the metabolite biomarkers for acupuncture treatment. Specifically, we generate and investigate the high-throughput metabolic profiles of acupuncture treatment at several acupoints in human. To select the subsets of metabolites that best characterize the acupuncture effect for each meridian point, an optimization model is proposed to identify biomarkers from high-dimensional metabolic data from case and control samples. Importantly, we use nearest centroid as the prototype to simultaneously minimize the number of selected features and the leave-one-out cross validation error of classifier. We compared the performance of LPFS to several state-of-the-art methods, such as SVM recursive feature elimination (SVM-RFE) and sparse multinomial logistic regression approach (SMLR). We find that our LPFS method tends to reveal a small set of metabolites with small standard deviation and large shifts, which exactly serves our requirement for good biomarker. Biologically, several metabolite biomarkers for acupuncture treatment are revealed and serve as the candidates for further mechanism investigation. Also biomakers derived from five meridian points, Zusanli (ST36), Liangmen (ST21), Juliao (ST3), Yanglingquan (GB34), and Weizhong (BL40), are compared for their similarity and difference, which provide evidence for the specificity of acupoints. Our result demonstrates that metabolic profiling might be a promising method to

  8. Integrated Data Collection Analysis (IDCA) Program - KClO4/Aluminum Mixture

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC IHD), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC IHD), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC IHD), Indian Head, MD (United States). Indian Head Division; Whinnery, LeRoy L. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Shelley, Timothy J. [Air Force Research Lab. (AFRL), Tyndall AFB, FL (United States); Reyes, Jose A. [Applied Research Associates (ARA), Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2012-01-17

    The Integrated Data Collection Analysis (IDCA) program is conducting a Proficiency Test for Small-Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of a mixture of KClO4 and aluminum—KClO4/Al mixture. This material was selected because of the challenge of performing SSST testing of a mixture of two solids. The mixture was found to be: 1) much less sensitive to impact than RDX, (LLNL being the exception) and PETN, 2) more sensitive to friction than RDX and PETN, and 3) extremely sensitive to spark. The thermal analysis showed little or no exothermic character. One prominent endothermic feature was observed in the temperature range studied and identified as a phase transition of KClO4.

  9. Integrated Data Collection Analysis (IDCA) Program - NaClO3/Icing Sugar

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Shelley, Timothy J. [Air Force Research Lab. (AFRL), Tyndall Air Force Base, FL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall Air Force Base, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-02-11

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of a mixture of NaClO3 and icing sugar—NaClO3/icing sugar mixture. The mixture was found to: be more sensitive than RDX but less sensitive than PETN in impact testing (180-grit sandpaper); be more sensitive than RDX and about the same sensitivity as PETN in BAM fiction testing; be less sensitive than RDX and PETN except for one participant found the mixture more sensitive than PETN in ABL ESD testing; and to have one to three exothermic features with the lowest temperature event occurring at ~ 160°C always observed in thermal testing. Variations in testing parameters also affected the sensitivity.

  10. Digitally Controlled Integrated Electronic Ballast with Dimming and Power Factor Correction Features

    Directory of Open Access Journals (Sweden)

    C. Aguilar-Castillo

    2010-12-01

    Full Text Available This paper presents a digitally controlled integrated electronic ballast with dimming and power factor correctionfeatures. The control circuit is based on a low-cost PIC16C71 microcontroller where the different strategies for energysaving have been implemented. The ballast is operating in closed loop achieving tight lamp current regulation througha digital Proportional-Integral algorithm. The integrated power stage is based on a frequency-controlled single-switchboost rectifier plus a half-bridge series resonant parallel loaded inverter sharing one power switch. The single-switchboost rectifier works in discontinuous inductor current mode with automatic power factor correction. Detailed analysisof the power stages and experimental results using 42-watt electronic ballast are presented.

  11. Enabling Valuation of Nutrition Integration into MBBS Program

    Directory of Open Access Journals (Sweden)

    Niikee Schoendorfer

    2015-01-01

    Full Text Available Good nutrition is the foundation for good health. While basic nutritional assessment is part of many medical consultations, it remains underutilized despite becoming increasingly recognized as important for chronic disease prevention and management. Many studies identify shortfalls in physicians’ knowledge and attitudes toward nutrition as a result of inadequate emphasis in medical school. Additional teaching about nutrition and nutritional assessment procedures was integrated within a first year module of a MBBS program. Blended learning techniques were employed to facilitate student engagement and sessions were evaluated via student response system technology (clickers or minute paper feedback. The initial survey to all medical students (n=1037 documented that less than half (45% felt they could discuss nutrition with patients. The majority (n=606 regularly consulted the internet for nutrition information, while only 163 utilised peer-reviewed journals. With the first year cohort (n=297 “clickers” revealed that 91% felt nutrition important to health care and 82% felt it important in general practice. 71% found using clickers an interesting enhancement, whilst 70% noted the nutrition content informative. Early nutrition teaching was well received by students. Long-term increases in nutritional information dissemination, particularly by influential health care workers, might benefit not only economies but also the health of society as a whole.

  12. Design Features of Product-Integrated PV: An Evaluation of Various Factors under Indoor Irradiance Conditions

    OpenAIRE

    Apostolou, G.

    2016-01-01

    This thesis explores the field of product-integrated photovoltaics (PIPV), a term which is used for all types of products that contain solar cells in one or more of their surfaces, aiming at providing power during the product’s use. Product-integrated photovoltaics (PIPV) began to be widely introduced around 2000, although the use of PV systems in products dates back to the 70s. PIPV includes products such as PV-powered boats, aircrafts, cars, bicycles, camping tents, street lights, recycling...

  13. Virtual Ribosome - a comprehensive DNA translation tool with support for integration of sequence feature annotation

    DEFF Research Database (Denmark)

    Wernersson, Rasmus

    2006-01-01

    Virtual Ribosome is a DNA translation tool with two areas of focus. ( i) Providing a strong translation tool in its own right, with an integrated ORF finder, full support for the IUPAC degenerate DNA alphabet and all translation tables defined by the NCBI taxonomy group, including the use...

  14. Investigation of Selected Surface Integrity Features of Duplex Stainless Steel (DSS) after Turning

    Czech Academy of Sciences Publication Activity Database

    Krolczyk, G.; Nieslony, P.; Legutko, S.; Hloch, Sergej; Samardžić, I.

    2015-01-01

    Roč. 54, č. 1 (2015), s. 91-94 ISSN 0543-5846 Institutional support: RVO:68145535 Keywords : duplex stainless steel * machining * turning * surface integrity * surface roughness Subject RIV: JQ - Machines ; Tools Impact factor: 0.959, year: 2014 http://hrcak.srce.hr/126702

  15. Inkjet-printed conductive features for rapid integration of electronic circuits in centrifugal microfluidics

    CSIR Research Space (South Africa)

    Kruger, J

    2015-05-01

    Full Text Available activation is therefore a critical prerequisite to improve wetability of the substrate surface to the ink. Wiping or washing with a solvent cleans loose particles and degreases the surface, while also increasing the surface energy. Solvents... visual appraisal of the printed dogbone structures in Figure 6 indicates feature shapes that are well defined and adherent on the substrate, while edge raggedness is noticeable on the widest line. There appears to be a "coffee-ring" effect where...

  16. Integrating angle-frequency domain synchronous averaging technique with feature extraction for gear fault diagnosis

    Science.gov (United States)

    Zhang, Shengli; Tang, J.

    2018-01-01

    Gear fault diagnosis relies heavily on the scrutiny of vibration responses measured. In reality, gear vibration signals are noisy and dominated by meshing frequencies as well as their harmonics, which oftentimes overlay the fault related components. Moreover, many gear transmission systems, e.g., those in wind turbines, constantly operate under non-stationary conditions. To reduce the influences of non-synchronous components and noise, a fault signature enhancement method that is built upon angle-frequency domain synchronous averaging is developed in this paper. Instead of being averaged in the time domain, the signals are processed in the angle-frequency domain to solve the issue of phase shifts between signal segments due to uncertainties caused by clearances, input disturbances, and sampling errors, etc. The enhanced results are then analyzed through feature extraction algorithms to identify the most distinct features for fault classification and identification. Specifically, Kernel Principal Component Analysis (KPCA) targeting at nonlinearity, Multilinear Principal Component Analysis (MPCA) targeting at high dimensionality, and Locally Linear Embedding (LLE) targeting at local similarity among the enhanced data are employed and compared to yield insights. Numerical and experimental investigations are performed, and the results reveal the effectiveness of angle-frequency domain synchronous averaging in enabling feature extraction and classification.

  17. An intelligent recovery progress evaluation system for ACL reconstructed subjects using integrated 3-D kinematics and EMG features.

    Science.gov (United States)

    Malik, Owais A; Senanayake, S M N Arosha; Zaheer, Dansih

    2015-03-01

    An intelligent recovery evaluation system is presented for objective assessment and performance monitoring of anterior cruciate ligament reconstructed (ACL-R) subjects. The system acquires 3-D kinematics of tibiofemoral joint and electromyography (EMG) data from surrounding muscles during various ambulatory and balance testing activities through wireless body-mounted inertial and EMG sensors, respectively. An integrated feature set is generated based on different features extracted from data collected for each activity. The fuzzy clustering and adaptive neuro-fuzzy inference techniques are applied to these integrated feature sets in order to provide different recovery progress assessment indicators (e.g., current stage of recovery, percentage of recovery progress as compared to healthy group, etc.) for ACL-R subjects. The system was trained and tested on data collected from a group of healthy and ACL-R subjects. For recovery stage identification, the average testing accuracy of the system was found above 95% (95-99%) for ambulatory activities and above 80% (80-84%) for balance testing activities. The overall recovery evaluation performed by the proposed system was found consistent with the assessment made by the physiotherapists using standard subjective/objective scores. The validated system can potentially be used as a decision supporting tool by physiatrists, physiotherapists, and clinicians for quantitative rehabilitation analysis of ACL-R subjects in conjunction with the existing recovery monitoring systems.

  18. Part 2 -- current program integrating strategies and lubrication technology

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, B.

    1996-12-01

    This paper is the second of two that describe the Predictive Maintenance Program for rotating machinery at the Palo Verde Nuclear Generating Station. The Predictive Maintenance program has been enhanced through organizational changes and improved interdisciplinary usage of technology. This paper will discuss current program strategies that have improved the interaction between the Vibration and Lube Oil programs. The {open_quotes}Lube Oil{close_quotes} view of the combined program along with case studies will then be presented.

  19. 3D Printed Unibody Lab-on-a-Chip: Features Survey and Check-Valves Integration

    Directory of Open Access Journals (Sweden)

    Germán Comina

    2015-04-01

    Full Text Available The unibody lab-on-a-chip (ULOC concept entails a fast and affordable micro-prototyping system built around a single monolithic 3D printed element (unibody. A consumer-grade stereo lithography (SL 3D printer can configure ULOCs with different forms of sample delivery, transport, handling and readout, while minimizing material costs and fabrication time. ULOC centralizes all complex fabrication procedures and replaces the need for clean room resources, delivering prototypes for less than 1 US$, which can be printed in 10 min and ready for testing in less than 30 min. Recent examples of ULOC integration of transport, chemical sensing for optical readout and flow mixing capabilities are discussed, as well as the integration of the first check-valves for ULOC devices. ULOC valves are strictly unidirectional up to 100 psi, show an exponential forward flow behavior up to 70 psi and can be entirely fabricated with the ULOC approach.

  20. Matching of array CGH and gene expression microarray features for the purpose of integrative genomic analyses

    Directory of Open Access Journals (Sweden)

    van Wieringen Wessel N

    2012-05-01

    Full Text Available Abstract Background An increasing number of genomic studies interrogating more than one molecular level is published. Bioinformatics follows biological practice, and recent years have seen a surge in methodology for the integrative analysis of genomic data. Often such analyses require knowledge of which elements of one platform link to those of another. Although important, many integrative analyses do not or insufficiently detail the matching of the platforms. Results We describe, illustrate and discuss six matching procedures. They are implemented in the R-package sigaR (available from Bioconductor. The principles underlying the presented matching procedures are generic, and can be combined to form new matching approaches or be applied to the matching of other platforms. Illustration of the matching procedures on a variety of data sets reveals how the procedures differ in the use of the available data, and may even lead to different results for individual genes. Conclusions Matching of data from multiple genomics platforms is an important preprocessing step for many integrative bioinformatic analysis, for which we present six generic procedures, both old and new. They have been implemented in the R-package sigaR, available from Bioconductor.

  1. An integrated measure of display clutter based on feature content, user knowledge and attention allocation factors.

    Science.gov (United States)

    Pankok, Carl; Kaber, David B

    2017-11-14

    Existing measures of display clutter in the literature generally exhibit weak correlations with task performance, which limits their utility in safety-critical domains. A literature review led to formulation of an integrated display data- and user knowledge-driven measure of display clutter. A driving simulation experiment was conducted in which participants were asked to search 'high' and 'low' clutter displays for navigation information. Data-driven measures and subjective perceptions of clutter were collected along with patterns of visual attention allocation and driving performance responses during time periods in which participants searched the navigation display for information. The new integrated measure was more strongly correlated with driving performance than other, previously developed measures of clutter, particularly in the case of low-clutter displays. Integrating display data and user knowledge factors with patterns of visual attention allocation shows promise for measuring display clutter and correlation with task performance, particularly for low-clutter displays. Practitioner Summary: A novel measure of display clutter was formulated, accounting for display data content, user knowledge states and patterns of visual attention allocation. The measure was evaluated in terms of correlations with driver performance in a safety-critical driving simulation study. The measure exhibited stronger correlations with task performance than previously defined measures.

  2. International Polar Year 2007: An Integrated Heliospheric and Oceanographic Program?

    Science.gov (United States)

    Johnson, G.; Davila, J.

    An international symposium SPerspectives of Modern Polar ResearchT was convened - in Bad Durkeim, Germany 2001 to celebrated the 175the anniversary of the birth of Georg von Neumayer. At that symposium the Nermayer Declaration was adopted to commemorate the 125th anniversary of the IPY in 2007. SA 125th year IPY program be initiated using new and present technologies to determine: 1 . Causes and effects of climatic variability-air/sea/ice interactins, and 2. Lithosphere dynamicsUevolution and history of crust and sedimentary cover. The po lar regions would be the focus.T Polar oceanographic contributions to global climate change are still a matter of conjecture, and to a large extent so are the extraterrestrial contributions. The proposed IPY would focus on these issues. As part of the global heat engine, the polar regions hav a major role in the worldSs transfer of energy, and the ocean/stmosphere system is known to be both an indicator and a componenet of climate change. It is clear that acomplex suite of significant, interrelated, atmospheric, oceanic and terrestrial changes has occurred in the the polsar regions in recent decades. These events are affecting every part of the polar environment and are having repercussions on society. In a similar vein an International Heliophysical Year (IHY) has been proposed to obtain a coordinated set of observations to study at the largest scale the solar genergated events that affect life and climate on Earth as has been documented in the Holocene sedimentary recofd. A modeling capability is the ultimate goal so the physical process can be tracked throughout the entire Sun-Earth system. This program will require an integrated, holistic system approach encompassing a side range of disciplines with new and improved technologies for long term measurements on the seabed, in the water column and in space over all seasons. Coordination, collaboration and documentation of an interated science plan with international scientific

  3. Integrated Task And Data Parallel Programming: Language Design

    Science.gov (United States)

    Grimshaw, Andrew S.; West, Emily A.

    1998-01-01

    his research investigates the combination of task and data parallel language constructs within a single programming language. There are an number of applications that exhibit properties which would be well served by such an integrated language. Examples include global climate models, aircraft design problems, and multidisciplinary design optimization problems. Our approach incorporates data parallel language constructs into an existing, object oriented, task parallel language. The language will support creation and manipulation of parallel classes and objects of both types (task parallel and data parallel). Ultimately, the language will allow data parallel and task parallel classes to be used either as building blocks or managers of parallel objects of either type, thus allowing the development of single and multi-paradigm parallel applications. 1995 Research Accomplishments In February I presented a paper at Frontiers '95 describing the design of the data parallel language subset. During the spring I wrote and defended my dissertation proposal. Since that time I have developed a runtime model for the language subset. I have begun implementing the model and hand-coding simple examples which demonstrate the language subset. I have identified an astrophysical fluid flow application which will validate the data parallel language subset. 1996 Research Agenda Milestones for the coming year include implementing a significant portion of the data parallel language subset over the Legion system. Using simple hand-coded methods, I plan to demonstrate (1) concurrent task and data parallel objects and (2) task parallel objects managing both task and data parallel objects. My next steps will focus on constructing a compiler and implementing the fluid flow application with the language. Concurrently, I will conduct a search for a real-world application exhibiting both task and data parallelism within the same program m. Additional 1995 Activities During the fall I collaborated

  4. Digital compared to screen-film mammography: breast cancer prognostic features in an organized screening program.

    Science.gov (United States)

    Prummel, Maegan V; Done, Susan J; Muradali, Derek; Majpruz, Vicky; Brown, Patrick; Jiang, Hedy; Shumak, Rene S; Yaffe, Martin J; Holloway, Claire M B; Chiarelli, Anna M

    2014-09-01

    Our previous study found cancer detection rates were equivalent for direct radiography compared to screen-film mammography, while rates for computed radiography were significantly lower. This study compares prognostic features of invasive breast cancers by type of mammography. Approved by the University of Toronto Research Ethics Board, this study identified invasive breast cancers diagnosed among concurrent cohorts of women aged 50-74 screened by direct radiography, computed radiography, or screen-film mammography from January 1, 2008 to December 31, 2009. During the study period, 816,232 mammograms were performed on 668,418 women, and 3,323 invasive breast cancers were diagnosed. Of 2,642 eligible women contacted, 2,041 participated (77.3 %). The final sample size for analysis included 1,405 screen-detected and 418 interval cancers (diagnosed within 24 months of a negative screening mammogram). Polytomous logistic regression was performed to evaluate the association between tumour characteristics and type of mammography, and between tumour characteristics and detection method. Odds ratios (OR) and 95 % confidence intervals (CI) were recorded. Cancers detected by computed radiography compared to screen-film mammography were significantly more likely to be lymph node positive (OR 1.94, 95 %CI 1.01-3.73) and have higher stage (II:I, OR 2.14, 95 %CI 1.11-4.13 and III/IV:I, OR 2.97, 95 %CI 1.02-8.59). Compared to screen-film mammography, significantly more cancers detected by direct radiography (OR 1.64, 95 %CI 1.12-2.38) were lymph node positive. Interval cancers had worse prognostic features compared to screen-detected cancers, irrespective of mammography type. Screening with computed radiography may lead to the detection of cancers with a less favourable stage distribution compared to screen-film mammography that may reflect a delayed diagnosis. Screening programs should re-evaluate their use of computed radiography for breast screening.

  5. Integrated siRNA design based on surveying of features associated with high RNAi effectiveness

    Directory of Open Access Journals (Sweden)

    Lin Dong

    2006-11-01

    Full Text Available Abstract Background Short interfering RNAs have allowed the development of clean and easily regulated methods for disruption of gene expression. However, while these methods continue to grow in popularity, designing effective siRNA experiments can be challenging. The various existing siRNA design guidelines suffer from two problems: they differ considerably from each other, and they produce high levels of false-positive predictions when tested on data of independent origins. Results Using a distinctly large set of siRNA efficacy data assembled from a vast diversity of origins (the siRecords data, containing records of 3,277 siRNA experiments targeting 1,518 genes, derived from 1,417 independent studies, we conducted extensive analyses of all known features that have been implicated in increasing RNAi effectiveness. A number of features having positive impacts on siRNA efficacy were identified. By performing quantitative analyses on cooperative effects among these features, then applying a disjunctive rule merging (DRM algorithm, we developed a bundle of siRNA design rule sets with the false positive problem well curbed. A comparison with 15 online siRNA design tools indicated that some of the rule sets we developed surpassed all of these design tools commonly used in siRNA design practice in positive predictive values (PPVs. Conclusion The availability of the large and diverse siRNA dataset from siRecords and the approach we describe in this report have allowed the development of highly effective and generally applicable siRNA design rule sets. Together with ever improving RNAi lab techniques, these design rule sets are expected to make siRNAs a more useful tool for molecular genetics, functional genomics, and drug discovery studies.

  6. Algorithms and FORTRAN programs to calculate classical collision integrals for realistic intermolecular potentials. [Classical transport integrals; SCAN; Coll

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, W.L.

    1979-11-29

    Numerical methods and computer programs are given to evaluate, for an arbitrary intermolecular potential, the classical transport collision integrals which appear in the kinetic theory of dilute gases. The method of Gaussian quadrature was employed to integrate the triple integral. A detailed discussion is given of the mathematics necessary to determine the boundaries of the individual integrations as well as a detailed analysis of errors introduced by the numerical procedures. Results for a recently published helium potential, the HFDHE2, are given. 5 references.

  7. Using the integrated nurse leadership program to reduce sepsis mortality.

    Science.gov (United States)

    Kliger, Julie; Singer, Sara J; Hoffman, Frank H

    2015-06-01

    The Integrated Nurse Leadership Program (INLP) is a collaborative improvement model focused on developing practical leadership skills of nurses and other frontline clinicians to lead quality improvement efforts. Sepsis is a major challenge to treat because it arises unpredictably and can progress rapidly. Nine San Francisco Bay Area hospitals participated in a 22-month INLP Sepsis Mortality Reduction Project to improve sepsis detection and management. The INLP focused on developing leadership and process improvement skills of nurses and other frontline clinicians. Teams of trained clinicians then implemented three strategies to improve early identification and timely treatment of sepsis: (1) sepsis screening of all patients, with diagnostic testing according to protocol; (2) timely treatment on the basis of key elements of Early Goal-Directed Therapy (EGDT); and (3) ongoing data review. Each hospital agreed to pursue the goal of reducing sepsis mortality by 15% by the end of the project. In the data collection period (baseline, July-December 2008 and project completion, January-June 2011), team members showed strong improvement in perceived leadership skills, team effectiveness, and ability to improve care quality. During this period, sepsis mortality for eight of the participating hospitals (Hospital 9 joined the project six months after it began) decreased by 43.7%-from 28% in the baseline period to 16% at project completion. Sepsis mortality rates trended downward for all hospitals, significantly decreasing (pone hospital, pmanagement of septic patients, hospitals participating in the INLP Sepsis Mortality Reduction Project achieved reductions in sepsis mortality during the study period and sustained reductions for more than one year later. The INLP model can be readily applied beyond sepsis management and mortality to other quality problems.

  8. Integrated Research on Midwestern Landscape Change: A Program Description and Progress Report

    Science.gov (United States)

    Paul H. Gobster; Robert G. Haight; David S. Shriner

    2000-01-01

    The USDA Forest Service North Central Research Station has embarked on a new integrated research and development program to identify and understand the development-related aspects of Midwestern landscape change. This paper describes the framework and scope of the Landscape Change Integrated Program and highlights projects begun during the first two years. Partnerships...

  9. SoftSearch: integration of multiple sequence features to identify breakpoints of structural variations.

    Directory of Open Access Journals (Sweden)

    Steven N Hart

    Full Text Available BACKGROUND: Structural variation (SV represents a significant, yet poorly understood contribution to an individual's genetic makeup. Advanced next-generation sequencing technologies are widely used to discover such variations, but there is no single detection tool that is considered a community standard. In an attempt to fulfil this need, we developed an algorithm, SoftSearch, for discovering structural variant breakpoints in Illumina paired-end next-generation sequencing data. SoftSearch combines multiple strategies for detecting SV including split-read, discordant read-pair, and unmated pairs. Co-localized split-reads and discordant read pairs are used to refine the breakpoints. RESULTS: We developed and validated SoftSearch using real and synthetic datasets. SoftSearch's key features are 1 not requiring secondary (or exhaustive primary alignment, 2 portability into established sequencing workflows, and 3 is applicable to any DNA-sequencing experiment (e.g. whole genome, exome, custom capture, etc.. SoftSearch identifies breakpoints from a small number of soft-clipped bases from split reads and a few discordant read-pairs which on their own would not be sufficient to make an SV call. CONCLUSIONS: We show that SoftSearch can identify more true SVs by combining multiple sequence features. SoftSearch was able to call clinically relevant SVs in the BRCA2 gene not reported by other tools while offering significantly improved overall performance.

  10. Understanding Legacy Features with Featureous

    DEFF Research Database (Denmark)

    Olszak, Andrzej; Jørgensen, Bo Nørregaard

    2011-01-01

    Feature-centric comprehension of source code is essential during software evolution. However, such comprehension is oftentimes difficult to achieve due the discrepancies between structural and functional units of object-oriented programs. We present a tool for feature-centric analysis of legacy...... Java programs called Featureous that addresses this issue. Featureous allows a programmer to easily establish feature-code traceability links and to analyze their characteristics using a number of visualizations. Featureous is an extension to the NetBeans IDE, and can itself be extended by third...

  11. Advanced Hybrid Spacesuit Concept Featuring Integrated Open Loop and Closed Loop Ventilation Systems

    Science.gov (United States)

    Daniel, Brian A.; Fitzpatrick, Garret R.; Gohmert, Dustin M.; Ybarra, Rick M.; Dub, Mark O.

    2013-01-01

    A document discusses the design and prototype of an advanced spacesuit concept that integrates the capability to function seamlessly with multiple ventilation system approaches. Traditionally, spacesuits are designed to operate both dependently and independently of a host vehicle environment control and life support system (ECLSS). Spacesuits that operate independent of vehicle-provided ECLSS services must do so with equipment selfcontained within or on the spacesuit. Suits that are dependent on vehicle-provided consumables must remain physically connected to and integrated with the vehicle to operate properly. This innovation is the design and prototype of a hybrid spacesuit approach that configures the spacesuit to seamlessly interface and integrate with either type of vehicular systems, while still maintaining the ability to function completely independent of the vehicle. An existing Advanced Crew Escape Suit (ACES) was utilized as the platform from which to develop the innovation. The ACES was retrofitted with selected components and one-off items to achieve the objective. The ventilation system concept was developed and prototyped/retrofitted to an existing ACES. Components were selected to provide suit connectors, hoses/umbilicals, internal breathing system ducting/ conduits, etc. The concept utilizes a lowpressure- drop, high-flow ventilation system that serves as a conduit from the vehicle supply into the suit, up through a neck seal, into the breathing helmet cavity, back down through the neck seal, out of the suit, and returned to the vehicle. The concept also utilizes a modified demand-based breathing system configured to function seamlessly with the low-pressure-drop closed-loop ventilation system.

  12. 49 CFR 192.909 - How can an operator change its integrity management program?

    Science.gov (United States)

    2010-10-01

    ... Transmission Pipeline Integrity Management § 192.909 How can an operator change its integrity management... 49 Transportation 3 2010-10-01 2010-10-01 false How can an operator change its integrity management program? 192.909 Section 192.909 Transportation Other Regulations Relating to Transportation...

  13. Software-Programmed Optical Networking with Integrated NFV Service Provisioning

    DEFF Research Database (Denmark)

    Mehmeri, Victor; Wang, Xi; Basu, Shrutarshi

    2017-01-01

    We showcase demonstrations of “program & compile” styled optical networking as well as open platforms & standards based NFV service provisioning using a proof-of-concept implementation of the Software-Programmed Networking Operating System (SPN OS).......We showcase demonstrations of “program & compile” styled optical networking as well as open platforms & standards based NFV service provisioning using a proof-of-concept implementation of the Software-Programmed Networking Operating System (SPN OS)....

  14. Multi-task feature selection in microarray data by binary integer programming

    OpenAIRE

    Lan, Liang; Vucetic, Slobodan

    2013-01-01

    A major challenge in microarray classification is that the number of features is typically orders of magnitude larger than the number of examples. In this paper, we propose a novel feature filter algorithm to select the feature subset with maximal discriminative power and minimal redundancy by solving a quadratic objective function with binary integer constraints. To improve the computational efficiency, the binary integer constraints are relaxed and a low-rank approximation to the quadratic ...

  15. Improving biological understanding and complex trait prediction by integrating prior information in genomic feature models

    DEFF Research Database (Denmark)

    Edwards, Stefan McKinnon

    externally founded information, such as KEGG pathways, Gene Ontology gene sets, or genomic features, and estimate the joint contribution of the genetic variants within these sets to complex trait phenotypes. The analysis of complex trait phenotypes is hampered by the myriad of genes that control the trait...... variant to be represented as different sets. We interpret this as separating the genomic signal from the noise. This is however not without issues, as in some populations, such as the Danish Holstein dairy cattle, the genetic variants can be highly correlated across multiple genes. Selecting one...... use cross validations to estimate the predictive ability of a set. --- The thesis consists of 3 chapters introducing the methodology of linear mixed models, their application, and evaluation by means of test statistics. Then 3 manuscripts in which we investigate the usage of our approach in Danish...

  16. General and Child and Adolescent Psychiatry Resident Training in Integrated Care: a Survey of Program Directors.

    Science.gov (United States)

    Reardon, Claudia L; Bentman, Adrienne; Cowley, Deborah S; Dunaway, Kristen; Forstein, Marshall; Girgis, Christina; Han, Jaesu; Hung, Erick; Jones, Jeralyn; Keeble, Tanya; McCarron, Robert M; Varley, Christopher K

    2015-08-01

    Integrated care models are an evidence-based approach for integrating physical and behavioral health services. The American Association of Directors of Psychiatric Residency Training Integrated Care Task Force sought to describe current practices for providing training in integrated care to general and child and adolescent psychiatry residents. Directors of US general and child and adolescent psychiatric residency training programs were anonymously surveyed to examine current practices in educating their residents in integrated care. Based on themes that emerged from the survey, the authors make recommendations for integrated care education of general and child and adolescent psychiatry residents. Fifty-two of 197 (26%) general and 36 of 111 (32%) child and adolescent program directors responded. Results demonstrate that a majority of responding general psychiatry (78%) and child and adolescent psychiatry (CAP) (72%) training programs offer integrated care rotations, many of which are electives for senior residents. The Veterans Health Administration (VA) and Federally Qualified Health Centers are common venues for such rotations. Sustainable funding of these rotations is a concern. Fewer than half of programs offer integrated care didactics. This report is intended to help program directors consider options for starting or optimizing their own integrated care curricula. Future research should examine the educational value, and the overall value to health care systems, of training in the integrated care model.

  17. Generation of Cosmological Flows in General Relativity (Features and Properties of Integrable Singularities)

    CERN Document Server

    Lukash, V N; Strokov, V N; 10.3367/UFNe.0182.201208k.0894

    2012-01-01

    We discuss status of the singularity problem in General Relativity and argue that the requirement that a physical solution must be completely free of singularities may be too strong. As an example, we consider properties of the integrable singularities and show that they represent light horizons separating T-regions of black and white holes. Connecting an astrophysical black hole to a white hole, they lead to a natural mechanism of generating new universes. Under favorable conditions the new universes will also contain black holes which, in their turn, will give rise to another generation of universes. In this case the cosmological evolutionary tree will continue to grow to form the "hyperverse". This scenario essentially differs from other known mechanisms, such as bounce, birth from "nothing", baby-universe scenario, etc.

  18. FEATURES OF TERRITORIAL INTEGRATION OF MARKETING COMMUNICATIONS IN THE CAUCASIAN MINERAL WATERS REGION

    Directory of Open Access Journals (Sweden)

    Михаил Влидимирович Беляев

    2013-10-01

    Full Text Available The purpose of the work is to describe the situation taken place with integration of marketing communications in the region. The author conducted research aimed at identifying the most popular and effective forms of communication with the consumer, allowing in detail to characterize the state of the advertising market of Caucasian Mineral Waters. Information concluded in article may be used by companies present in the Caucasian Mineral Waters region, to form notion about the effectiveness of the regional channels of communication with customers and building a more efficient model of advertising policy, also its could be useful for specialists, which are working in marketing communication and advertising sphere.DOI: http://dx.doi.org/10.12731/2218-7405-2013-9-34

  19. Promoting convergence: The integrated graduate program in physical and engineering biology at Yale University, a new model for graduate education

    Science.gov (United States)

    Noble, Dorottya B.; Mochrie, Simon G. J.; O'Hern, Corey S.; Pollard, Thomas D.

    2016-01-01

    Abstract In 2008, we established the Integrated Graduate Program in Physical and Engineering Biology (IGPPEB) at Yale University. Our goal was to create a comprehensive graduate program to train a new generation of scientists who possess a sophisticated understanding of biology and who are capable of applying physical and quantitative methodologies to solve biological problems. Here we describe the framework of the training program, report on its effectiveness, and also share the insights we gained during its development and implementation. The program features co‐teaching by faculty with complementary specializations, student peer learning, and novel hands‐on courses that facilitate the seamless blending of interdisciplinary research and teaching. It also incorporates enrichment activities to improve communication skills, engage students in science outreach, and foster a cohesive program cohort, all of which promote the development of transferable skills applicable in a variety of careers. The curriculum of the graduate program is integrated with the curricular requirements of several Ph.D.‐granting home programs in the physical, engineering, and biological sciences. Moreover, the wide‐ranging recruiting activities of the IGPPEB serve to enhance the quality and diversity of students entering graduate school at Yale. We also discuss some of the challenges we encountered in establishing and optimizing the program, and describe the institution‐level changes that were catalyzed by the introduction of the new graduate program. The goal of this article is to serve as both an inspiration and as a practical “how to” manual for those who seek to establish similar programs at their own institutions. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):537–549, 2016. PMID:27292366

  20. Promoting convergence: The integrated graduate program in physical and engineering biology at Yale University, a new model for graduate education.

    Science.gov (United States)

    Noble, Dorottya B; Mochrie, Simon G J; O'Hern, Corey S; Pollard, Thomas D; Regan, Lynne

    2016-11-12

    In 2008, we established the Integrated Graduate Program in Physical and Engineering Biology (IGPPEB) at Yale University. Our goal was to create a comprehensive graduate program to train a new generation of scientists who possess a sophisticated understanding of biology and who are capable of applying physical and quantitative methodologies to solve biological problems. Here we describe the framework of the training program, report on its effectiveness, and also share the insights we gained during its development and implementation. The program features co-teaching by faculty with complementary specializations, student peer learning, and novel hands-on courses that facilitate the seamless blending of interdisciplinary research and teaching. It also incorporates enrichment activities to improve communication skills, engage students in science outreach, and foster a cohesive program cohort, all of which promote the development of transferable skills applicable in a variety of careers. The curriculum of the graduate program is integrated with the curricular requirements of several Ph.D.-granting home programs in the physical, engineering, and biological sciences. Moreover, the wide-ranging recruiting activities of the IGPPEB serve to enhance the quality and diversity of students entering graduate school at Yale. We also discuss some of the challenges we encountered in establishing and optimizing the program, and describe the institution-level changes that were catalyzed by the introduction of the new graduate program. The goal of this article is to serve as both an inspiration and as a practical "how to" manual for those who seek to establish similar programs at their own institutions. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):537-549, 2016. © 2016 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology.

  1. Montana Integrated Carbon to Liquids (ICTL) Demonstration Program

    Energy Technology Data Exchange (ETDEWEB)

    Fiato, Rocco A. [Accelergy Corporation, Houston, TX (United States); Sharma, Ramesh [Univ. of North Dakota, Grand Forks, ND (United States). Energy & Environmental Research Center (EERC); Allen, Mark [Accelergy Corporation, Houston, TX (United States). Integrated Carbon Solutions; Peyton, Brent [Montana State Univ., Bozeman, MT (United States); Macur, Richard [Montana State Univ., Bozeman, MT (United States). Dept. of Land Resources and Environmental Sciences; Cameron, Jemima [Australian Energy Company Ltd., Hovea (Australia). Australian American Energy Corporation (AAEC)

    2013-12-01

    Integrated carbon-to-liquids technology (ICTL) incorporates three basic processes for the conversion of a wide range of feedstocks to distillate liquid fuels: (1) Direct Microcatalytic Coal Liquefaction (MCL) is coupled with biomass liquefaction via (2) Catalytic Hydrodeoxygenation and Isomerization (CHI) of fatty acid methyl esters (FAME) or trigylceride fatty acids (TGFA) to produce liquid fuels, with process derived (3) CO2 Capture and Utilization (CCU) via algae production and use in BioFertilizer for added terrestrial sequestration of CO2, or as a feedstock for MCL and/or CHI. This novel approach enables synthetic fuels production while simultaneously meeting EISA 2007 Section 526 targets, minimizing land use and water consumption, and providing cost competitive fuels at current day petroleum prices. ICTL was demonstrated with Montana Crow sub-bituminous coal in MCL pilot scale operations at the Energy and Environmental Research Center at the University of North Dakota (EERC), with related pilot scale CHI studies conducted at the University of Pittsburgh Applied Research Center (PARC). Coal-Biomass to Liquid (CBTL) Fuel samples were evaluated at the US Air Force Research Labs (AFRL) in Dayton and greenhouse tests of algae based BioFertilizer conducted at Montana State University (MSU). Econometric modeling studies were also conducted on the use of algae based BioFertilizer in a wheat-camelina crop rotation cycle. We find that the combined operation is not only able to help boost crop yields, but also to provide added crop yields and associated profits from TGFA (from crop production) for use an ICTL plant feedstock. This program demonstrated the overall viability of ICTL in pilot scale operations. Related work on the Life Cycle Assessment (LCA) of a Montana project indicated that CCU could be employed very effectively to reduce the overall carbon footprint of the MCL/CHI process. Plans are currently being made to conduct larger

  2. A method of evolving novel feature extraction algorithms for detecting buried objects in FLIR imagery using genetic programming

    Science.gov (United States)

    Paino, A.; Keller, J.; Popescu, M.; Stone, K.

    2014-06-01

    In this paper we present an approach that uses Genetic Programming (GP) to evolve novel feature extraction algorithms for greyscale images. Our motivation is to create an automated method of building new feature extraction algorithms for images that are competitive with commonly used human-engineered features, such as Local Binary Pattern (LBP) and Histogram of Oriented Gradients (HOG). The evolved feature extraction algorithms are functions defined over the image space, and each produces a real-valued feature vector of variable length. Each evolved feature extractor breaks up the given image into a set of cells centered on every pixel, performs evolved operations on each cell, and then combines the results of those operations for every cell using an evolved operator. Using this method, the algorithm is flexible enough to reproduce both LBP and HOG features. The dataset we use to train and test our approach consists of a large number of pre-segmented image "chips" taken from a Forward Looking Infrared Imagery (FLIR) camera mounted on the hood of a moving vehicle. The goal is to classify each image chip as either containing or not containing a buried object. To this end, we define the fitness of a candidate solution as the cross-fold validation accuracy of the features generated by said candidate solution when used in conjunction with a Support Vector Machine (SVM) classifier. In order to validate our approach, we compare the classification accuracy of an SVM trained using our evolved features with the accuracy of an SVM trained using mainstream feature extraction algorithms, including LBP and HOG.

  3. 47 CFR 76.504 - Limits on carriage of vertically integrated programming.

    Science.gov (United States)

    2010-10-01

    ... programming. 76.504 Section 76.504 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST... Limits on carriage of vertically integrated programming. (a) Except as otherwise provided in this section... national video programming services owned by the cable operator or in which the cable operator has an...

  4. An Integrative Suicide Prevention Program for Visitor Charcoal Burning Suicide and Suicide Pact

    Science.gov (United States)

    Wong, Paul W. C.; Liu, Patricia M. Y.; Chan, Wincy S. C.; Law, Y. W.; Law, Steven C. K.; Fu, King-Wa; Li, Hana S. H.; Tso, M. K.; Beautrais, Annette L.; Yip, Paul S. F.

    2009-01-01

    An integrative suicide prevention program was implemented to tackle an outbreak of visitor charcoal burning suicides in Cheung Chau, an island in Hong Kong, in 2002. This study evaluated the effectiveness of the program. The numbers of visitor suicides reduced from 37 deaths in the 51 months prior to program implementation to 6 deaths in the 42…

  5. Active Participation of Integrated Development Environments in the Teaching of Object-Oriented Programming

    Science.gov (United States)

    Depradine, Colin; Gay, Glenda

    2004-01-01

    With the strong link between programming and the underlying technology, the incorporation of computer technology into the teaching of a programming language course should be a natural progression. However, the abstract nature of programming can make such integration a difficult prospect to achieve. As a result, the main development tool, the…

  6. Adding Value through Program Integration: A Kayaking Model (Rental, Retail, Repair, Clinics and Outings).

    Science.gov (United States)

    Poff, Raymond

    Outdoor programs can offset initial investment costs in services and products by developing integrated program areas. The experience of Outdoors Unlimited, a recently created kayaking program at Brigham Young University (Utah), is provided as a model. The purchase of 11 kayaks for rental was followed by the introduction of retail sales, repair…

  7. Key Features of Management of Technology (MoT) Undergraduate Program in Malaysia

    Science.gov (United States)

    Shamsuddin, Alina; Abdullah, Nor Hazana; Wahab, Eta

    2011-01-01

    Management of Technology (MoT) Education is growing both in numbers and importance. There are more than 200 universities in the world that are offering MoT programs. However, these universities have taken different approaches with respect to the names and designs of the programs. In Malaysia, some of the programs are known as Technology…

  8. The Performance Enhancement Group Program: Integrating Sport Psychology and Rehabilitation

    OpenAIRE

    Granito, Vincent J.; Hogan, Jeffery B.; Varnum, Lisa K.

    1995-01-01

    In an effort to improve the psychological health of the athlete who has sustained an injury, the Performance Enhancement Group program for injured athletes was created. This paper will offer a model for the Performance Enhancement Group program as a way to: 1) support the athlete, both mentally and physically; 2) deal with the demands of rehabilitation; and 3) facilitate the adjustments the athlete has to make while being out of the competitive arena. The program consists of responsibilities ...

  9. Exploring the Unique Features of a First Nations Graduate-Level Social Work Program

    Directory of Open Access Journals (Sweden)

    Ralph C. Bodor

    2015-03-01

    Full Text Available Recently, a one-time cohort of graduate-level social work students completed a unique MSW program. The program was delivered in partnership between the Faculty of Social Work, University of Calgary and Blue Quills First Nations College and, of the twenty four graduates; twenty-one were of First Nations or Me´tis ancestry. The program honored traditional knowledge and ways of learning combined with a critical analysis of Western perspectives of social work knowledge. Strong fiscal resources enabled the program to establish a formal support network for the students and to support the development of Indigenous curriculum and programming that encouraged success for the students. The program was fundamentally different than urban on-campus programs while still maintaining graduate level accreditation requirements. This analysis of the program required the use of Indigenous Research Methodology to collect and create an understanding of the program. Instructors commented on the centered, empowered, balanced, and congruent students. The formal and informal, concrete and invisible supports to the students ensured the success of this program and this cohort of students. As one student commented, the program started in ceremony, ended in ceremony, and could not fail within the context ceremony.

  10. SITE-94. Discrete-feature modelling of the Aespoe site: 2. Development of the integrated site-scale model

    Energy Technology Data Exchange (ETDEWEB)

    Geier, J.E. [Golder Associates AB, Uppsala (Sweden)

    1996-12-01

    A 3-dimensional, discrete-feature hydrological model is developed. The model integrates structural and hydrologic data for the Aespoe site, on scales ranging from semi regional fracture zones to individual fractures in the vicinity of the nuclear waste canisters. Hydrologic properties of the large-scale structures are initially estimated from cross-hole hydrologic test data, and automatically calibrated by numerical simulation of network flow, and comparison with undisturbed heads and observed drawdown in selected cross-hole tests. The calibrated model is combined with a separately derived fracture network model, to yield the integrated model. This model is partly validated by simulation of transient responses to a long-term pumping test and a convergent tracer test, based on the LPT2 experiment at Aespoe. The integrated model predicts that discharge from the SITE-94 repository is predominantly via fracture zones along the eastern shore of Aespoe. Similar discharge loci are produced by numerous model variants that explore uncertainty with regard to effective semi regional boundary conditions, hydrologic properties of the site-scale structures, and alternative structural/hydrological interpretations. 32 refs.

  11. Academic Autonomy for Adult Degree Programs: Independence with Integration

    Science.gov (United States)

    Curry, Judson

    2012-01-01

    North Park University's adult program has moved steadily from a centralized governance structure toward a more distributed structure in many ways. The School of Adult Learning hires its own faculty, some of whom are full time in the adult program. The school also has autonomy over academic policy. Ultimately, this academic autonomy has fostered…

  12. The engineering design integration (EDIN) system. [digital computer program complex

    Science.gov (United States)

    Glatt, C. R.; Hirsch, G. N.; Alford, G. E.; Colquitt, W. N.; Reiners, S. J.

    1974-01-01

    A digital computer program complex for the evaluation of aerospace vehicle preliminary designs is described. The system consists of a Univac 1100 series computer and peripherals using the Exec 8 operating system, a set of demand access terminals of the alphanumeric and graphics types, and a library of independent computer programs. Modification of the partial run streams, data base maintenance and construction, and control of program sequencing are provided by a data manipulation program called the DLG processor. The executive control of library program execution is performed by the Univac Exec 8 operating system through a user established run stream. A combination of demand and batch operations is employed in the evaluation of preliminary designs. Applications accomplished with the EDIN system are described.

  13. Discriminant Feature Selection by Genetic Programming: Towards a domain independent multi-class object detection system.

    Directory of Open Access Journals (Sweden)

    Jacques-André Landry

    2005-02-01

    Full Text Available In order to implement a multi-class object detection system, an efficient object representation is needed; in this short paper, we present a feature selection method based on the Genetic Algorithm paradigm. This method allows for the identification of a set of features that best represent the classes in the problem at hand. The idea would then be to have a broad set of features to describe any object, and then to use the presented feature selection method to adapt the description to the actual needs of the classification problem. Furthermore, the tree like solutions generated by the method can be interpreted and modified for increased generality. A brief review of literature, the first implementation of the method and the first results are presented here. The method shows potential to be used as a building block of a detection system, although further experimentation is underway in order to fully asses the power of the method.

  14. INDDGO: Integrated Network Decomposition & Dynamic programming for Graph Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Groer, Christopher S [ORNL; Sullivan, Blair D [ORNL; Weerapurage, Dinesh P [ORNL

    2012-10-01

    It is well-known that dynamic programming algorithms can utilize tree decompositions to provide a way to solve some \\emph{NP}-hard problems on graphs where the complexity is polynomial in the number of nodes and edges in the graph, but exponential in the width of the underlying tree decomposition. However, there has been relatively little computational work done to determine the practical utility of such dynamic programming algorithms. We have developed software to construct tree decompositions using various heuristics and have created a fast, memory-efficient dynamic programming implementation for solving maximum weighted independent set. We describe our software and the algorithms we have implemented, focusing on memory saving techniques for the dynamic programming. We compare the running time and memory usage of our implementation with other techniques for solving maximum weighted independent set, including a commercial integer programming solver and a semi-definite programming solver. Our results indicate that it is possible to solve some instances where the underlying decomposition has width much larger than suggested by the literature. For certain types of problems, our dynamic programming code runs several times faster than these other methods.

  15. Generic multiset programming for language-integrated querying

    DEFF Research Database (Denmark)

    Henglein, Fritz; Larsen, Ken Friis

    2010-01-01

    This paper demonstrates how relational algebraic programming based on efficient symbolic representations of multisets and operations on them can be applied to the query sublanguage of SQL in a type-safe fashion. In essence, it provides a library for naïve programming with multisets in a generalized...... SQL-style fashion, but avoids many cases of asymptotically inefficient nested iteration through cross-products....

  16. Integrating a Supplemental Vocabulary Instruction Program into an EFL Curriculum

    OpenAIRE

    ヒューバート, ラッセル ポール; ゴーベル, ピーター

    2012-01-01

    This article describes a supplemental vocabulary instruction program piloted in the KSU Faculty of Cultural Studies during the 2011 academic year. The program was created to enhance the depth of vocabulary knowledge and active usage of English vocabulary of first-year students (N=230). Initial student vocabulary knowledge levels were evaluated by a Vocabulary Levels Test (VLT) examination at the beginning of the academic year. A vocabulary textbook series was selected for the required reading...

  17. Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data.

    Science.gov (United States)

    Koleti, Amar; Terryn, Raymond; Stathias, Vasileios; Chung, Caty; Cooper, Daniel J; Turner, John P; Vidovic, Dušica; Forlin, Michele; Kelley, Tanya T; D'Urso, Alessandro; Allen, Bryce K; Torre, Denis; Jagodnik, Kathleen M; Wang, Lily; Jenkins, Sherry L; Mader, Christopher; Niu, Wen; Fazel, Mehdi; Mahi, Naim; Pilarczyk, Marcin; Clark, Nicholas; Shamsaei, Behrouz; Meller, Jarek; Vasiliauskas, Juozas; Reichard, John; Medvedovic, Mario; Ma'ayan, Avi; Pillai, Ajay; Schürer, Stephan C

    2017-11-13

    The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national consortium funded by the NIH to generate a diverse and extensive reference library of cell-based perturbation-response signatures, along with novel data analytics tools to improve our understanding of human diseases at the systems level. In contrast to other large-scale data generation efforts, LINCS Data and Signature Generation Centers (DSGCs) employ a wide range of assay technologies cataloging diverse cellular responses. Integration of, and unified access to LINCS data has therefore been particularly challenging. The Big Data to Knowledge (BD2K) LINCS Data Coordination and Integration Center (DCIC) has developed data standards specifications, data processing pipelines, and a suite of end-user software tools to integrate and annotate LINCS-generated data, to make LINCS signatures searchable and usable for different types of users. Here, we describe the LINCS Data Portal (LDP) (http://lincsportal.ccs.miami.edu/), a unified web interface to access datasets generated by the LINCS DSGCs, and its underlying database, LINCS Data Registry (LDR). LINCS data served on the LDP contains extensive metadata and curated annotations. We highlight the features of the LDP user interface that is designed to enable search, browsing, exploration, download and analysis of LINCS data and related curated content. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  18. Building relationships and facilitating immigrant community integration: An evaluation of a Cultural Navigator Program.

    Science.gov (United States)

    Thomas, Rebecca L; Chiarelli-Helminiak, Christina M; Ferraj, Brunilda; Barrette, Kyle

    2016-04-01

    Despite the long history of immigration in the United States, communities around the country struggle to integrate newcomers into the economic, cultural, and political spheres of society. Utilizing results from the program evaluation of one public library's Cultural Navigator Program, the authors illustrate how communities and public institutions can promote integration and relationship-building between newly arrived immigrants and long-time residents. Existing social networks within receiving communities, conceptualized in this article as social capital, were leveraged to build capacity among newly arrived immigrants and foster inclusivity and integration at the community level. As a place of intervention, public libraries are suggested as a safe and shared space where community integration can be fostered. Insights derived from the evaluation inform a discussion on engaging approaches to immigrant integration. Lessons learned and recommendations for program evaluators and administrators are provided. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Lessons learned from the scaling-up of a weekly multimicronutrient supplementation program in the integrated food security program (PISA).

    Science.gov (United States)

    Lechtig, Aarón; Gross, Rainer; Vivanco, Oscar Aquino; Gross, Ursula; López de Romaña, Daniel

    2006-01-01

    Weekly multimicronutrient supplementation was initiated as an appropriate intervention to protect poor urban populations from anemia. To identify the lessons learned from the Integrated Food Security Program (Programa Integrado de Seguridad Alimentaria [PISA]) weekly multimicronutrient supplementation program implemented in poor urban populations of Chiclayo, Peru. Data were collected from a 12-week program in which multimicronutrient supplements were provided weekly to women and adolescent girls 12 through 44 years of age and children under 5 years of age. A baseline survey was first conducted. Within the weekly multimicronutrient supplementation program, information was collected on supplement distribution, compliance, biological effectiveness, and cost. Supplementation, fortification, and dietary strategies can be integrated synergistically within a micronutrient intervention program. To ensure high cost-effectiveness of a weekly multimicronutrient supplementation program, the following conditions need to be met: the program should be implemented twice a year for 4 months; the program should be simultaneously implemented at the household (micro), community (meso), and national (macro) levels; there should be governmental participation from health and other sectors; and there should be community and private sector participation. Weekly multimicronutrient supplementation programs are cost effective options in urban areas with populations at low risk of energy deficiency and high risk of micronutrient deficiencies.

  20. Integrating the IEP and SOI with Educational Programing for the Gifted.

    Science.gov (United States)

    Hedbring, Charles; Rubenzer, Ronald

    1979-01-01

    The paper investigates a strategy for integrating the IEP (individualized educational plan) and J. Guilford's Structure-of-Intellect (SOI) in order to promote an accountability based approach to differentiated programing for the gifted classroom student. (Author/PHR)

  1. Postpartum Family Planning During Sociopolitical Transition: Findings from an Integrated Community-Based Program in Egypt

    National Research Council Canada - National Science Library

    Chelsea M. Cooper; Elaine Charurat; Issam El-Adawi; Young-Mi Kim; Mark R. Emerson; Wael Zaki; Anne Schuster

    2016-01-01

    .... : A quasi-experimental evaluation of an integrated reproductive and maternal and child health program implemented in selected sites in Upper and Lower Egypt was conducted between 2012 and 2014...

  2. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

    NARCIS (Netherlands)

    Arts, R.J; Novakovic, B.; Horst, R; Carvalho, A.; Bekkering, S.; Lachmandas, E.; Rodrigues, F.; Silvestre, R.; Cheng, S.C.; Wang, S.; Habibi, E.; Goncalves, L.G.; Mesquita, I.; Cunha, C.; Laarhoven, A van; Veerdonk, F.L van de; Williams, D.L.; Meer, J.W van der; Logie, C.; O'Neill, L.A.; Dinarello, C.A.; Riksen, N.P; Crevel, R. van; Clish, C.; Notebaart, R.A; Joosten, L.A.; Stunnenberg, H.G.; Xavier, R.J.; Netea, M.G

    2016-01-01

    Induction of trained immunity (innate immune memory) is mediated by activation of immune and metabolic pathways that result in epigenetic rewiring of cellular functional programs. Through network-level integration of transcriptomics and metabolomics data, we identify glycolysis, glutaminolysis, and

  3. Automated identification of protein-ligand interaction features using Inductive Logic Programming: a hexose binding case study

    Directory of Open Access Journals (Sweden)

    A Santos Jose C

    2012-07-01

    Full Text Available Abstract Background There is a need for automated methods to learn general features of the interactions of a ligand class with its diverse set of protein receptors. An appropriate machine learning approach is Inductive Logic Programming (ILP, which automatically generates comprehensible rules in addition to prediction. The development of ILP systems which can learn rules of the complexity required for studies on protein structure remains a challenge. In this work we use a new ILP system, ProGolem, and demonstrate its performance on learning features of hexose-protein interactions. Results The rules induced by ProGolem detect interactions mediated by aromatics and by planar-polar residues, in addition to less common features such as the aromatic sandwich. The rules also reveal a previously unreported dependency for residues cys and leu. They also specify interactions involving aromatic and hydrogen bonding residues. This paper shows that Inductive Logic Programming implemented in ProGolem can derive rules giving structural features of protein/ligand interactions. Several of these rules are consistent with descriptions in the literature. Conclusions In addition to confirming literature results, ProGolem’s model has a 10-fold cross-validated predictive accuracy that is superior, at the 95% confidence level, to another ILP system previously used to study protein/hexose interactions and is comparable with state-of-the-art statistical learners.

  4. Technology Integration: A Research-Based Professional Development Program

    Science.gov (United States)

    Faulder, Tori Rose

    2011-01-01

    This research-based thesis project explains the governmental acts and policies, investors, and other stakeholders who have worked to promote, question, and explore the use of information and communication technologies (ICT) in the classroom. Research suggests that best-practice ICT integration requires using ICT alongside constructivist pedagogy.…

  5. Optimising an integrated crop-livestock farm using risk programming ...

    African Journals Online (AJOL)

    Numerous studies have analysed farm planning decisions focusing on producer risk preferences. Few studies have focussed on the farm planning decisions in an integrated croplivestock farm context. Income variability and means of managing risk continues to receive much attention in farm planning research. Different risk ...

  6. Learning SQL Programming with Interactive Tools: From Integration to Personalization

    Science.gov (United States)

    Brusilovsky, Pete; Sosnovsky, Sergey; Yudelson, Michael V.; Lee, Danielle H.; Zadorozhny, Vladimir; Zhou, Xin

    2010-01-01

    Rich, interactive eLearning tools receive a lot of attention nowadays from both practitioners and researchers. However, broader dissemination of these tools is hindered by the technical difficulties of their integration into existing platforms. This article explores the technical and conceptual problems of using several interactive educational…

  7. Sustainable Procurement: Integrating Classroom Learning with University Sustainability Programs

    Science.gov (United States)

    Goldschmidt, Kyle; Harrison, Terry; Holtry, Matthew; Reeh, Jeremy

    2013-01-01

    Organizations are facing increased pressure from various stakeholders to address issues of sustainability, resulting in a growing demand for sustainability education and training. Procurement groups remain the key drivers of many sustainability-related strategies, placing pressure on universities to integrate sustainability concepts into the…

  8. High performance organic integrated device with ultraviolet photodetective and electroluminescent properties consisting of a charge-transfer-featured naphthalimide derivative

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Hanyu; Wang, Xu; Yu, Junsheng, E-mail: luzhiyun@scu.edu.cn, E-mail: jsyu@uestc.edu.cn [State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu 610054 (China); Zhou, Jie; Lu, Zhiyun, E-mail: luzhiyun@scu.edu.cn, E-mail: jsyu@uestc.edu.cn [College of Chemistry, Sichuan University, Chengdu 610064 (China)

    2014-08-11

    A high performance organic integrated device (OID) with ultraviolet photodetective and electroluminescent (EL) properties was fabricated by using a charge-transfer-featured naphthalimide derivative of 6-(3,5-bis-[9-(4-t-butylphenyl)-9H-carbazol-3-yl]-phenoxy)-2- (4-t-butylphenyl)-benzo[de]isoquinoline-1,3-dione (CzPhONI) as the active layer. The results showed that the OID had a high detectivity of 1.5 × 10{sup 11} Jones at −3 V under the UV-350 nm illumination with an intensity of 0.6 mW/cm{sup 2}, and yielded an exciplex EL light emission with a maximum brightness of 1437 cd/m{sup 2}. Based on the energy band diagram, both the charge transfer feature of CzPhONI and matched energy level alignment were responsible for the dual ultraviolet photodetective and EL functions of OID.

  9. Deep Fault Recognizer: An Integrated Model to Denoise and Extract Features for Fault Diagnosis in Rotating Machinery

    Directory of Open Access Journals (Sweden)

    Xiaojie Guo

    2016-12-01

    Full Text Available Fault diagnosis in rotating machinery is significant to avoid serious accidents; thus, an accurate and timely diagnosis method is necessary. With the breakthrough in deep learning algorithm, some intelligent methods, such as deep belief network (DBN and deep convolution neural network (DCNN, have been developed with satisfactory performances to conduct machinery fault diagnosis. However, only a few of these methods consider properly dealing with noises that exist in practical situations and the denoising methods are in need of extensive professional experiences. Accordingly, rethinking the fault diagnosis method based on deep architectures is essential. Hence, this study proposes an automatic denoising and feature extraction method that inherently considers spatial and temporal correlations. In this study, an integrated deep fault recognizer model based on the stacked denoising autoencoder (SDAE is applied to both denoise random noises in the raw signals and represent fault features in fault pattern diagnosis for both bearing rolling fault and gearbox fault, and trained in a greedy layer-wise fashion. Finally, the experimental validation demonstrates that the proposed method has better diagnosis accuracy than DBN, particularly in the existing situation of noises with superiority of approximately 7% in fault diagnosis accuracy.

  10. Integration of Academic and Vocational Programs in Illinois Community Colleges. The Status of Integration Activities Funded through the Quality Assurance Program.

    Science.gov (United States)

    Illinois Univ., Urbana. Dept. of Vocational and Technical Education.

    Quality Assurance Program (QAP) integration activities were studied at eight Illinois community and junior colleges. Data collection involved telephone interviews with career deans at the colleges, 11 follow-up site observations, and attendance at a regional vocational education system directors meeting. When classroom observations occurred,…

  11. Clinical capabilities of graduates of an outcomes-based integrated medical program

    Directory of Open Access Journals (Sweden)

    Scicluna Helen A

    2012-06-01

    Full Text Available Abstract Background The University of New South Wales (UNSW Faculty of Medicine replaced its old content-based curriculum with an innovative new 6-year undergraduate entry outcomes-based integrated program in 2004. This paper is an initial evaluation of the perceived and assessed clinical capabilities of recent graduates of the new outcomes-based integrated medical program compared to benchmarks from traditional content-based or process-based programs. Method Self-perceived capability in a range of clinical tasks and assessment of medical education as preparation for hospital practice were evaluated in recent graduates after 3 months working as junior doctors. Responses of the 2009 graduates of the UNSW’s new outcomes-based integrated medical education program were compared to those of the 2007 graduates of UNSW’s previous content-based program, to published data from other Australian medical schools, and to hospital-based supervisor evaluations of their clinical competence. Results Three months into internship, graduates from UNSW’s new outcomes-based integrated program rated themselves to have good clinical and procedural skills, with ratings that indicated significantly greater capability than graduates of the previous UNSW content-based program. New program graduates rated themselves significantly more prepared for hospital practice in the confidence (reflective practice, prevention (social aspects of health, interpersonal skills (communication, and collaboration (teamwork subscales than old program students, and significantly better or equivalent to published benchmarks of graduates from other Australian medical schools. Clinical supervisors rated new program graduates highly capable for teamwork, reflective practice and communication. Conclusions Medical students from an outcomes-based integrated program graduate with excellent self-rated and supervisor-evaluated capabilities in a range of clinically-relevant outcomes. The program

  12. Utilisation of Perkin-Elmer Operating System Features to Optimise Programming Efficiency

    OpenAIRE

    Gray, L.S.; Morris, A.S.

    1982-01-01

    This paper consists of printed notes given as the first lecture of a two-part special lecture course on efficient programming. Emphasis is laid on on efficient programming in relation to the hardware and operating system of the Perkin-Elmer 3220 computer, although the principles embodied are in general, universally applicable. The functioning of the operating system and its interaction with the hardware of the computer is explained in considerable detail, as this is felt a necessary prerequis...

  13. The Human Factor: Student Reactions to the Integration of Personal Dispositions into a Counseling Program

    Science.gov (United States)

    Gibbons, Melinda M.; Cochran, Jeff L.; Spurgeon, Shawn; Diambra, Joel F.

    2013-01-01

    The authors explored student reactions to the integration of personal dispositions, or characteristic attitudes, into a counseling program. Results suggested participants liked focusing on personal dispositions and were able to identify areas of personal growth related to these characteristics. Integrating humanistic principles by using…

  14. Views on and Practices of Integrating Theory and Practice in Teacher Education Programs in Atlantic Canada

    Science.gov (United States)

    Falkenberg, Thomas; Goodnough, Karen; MacDonald, Ronald J.

    2014-01-01

    The need for and lack of integration of theory and practice in initial teacher education programs has been discussed as a central issue for teacher education. This article reports on a study that surveyed university-based teacher educators in Atlantic Canada on their perspectives regarding how theory and practice can be integrated, how they and…

  15. Changing Personal Epistemologies in Early Childhood Pre-Service Teachers Using an Integrated Teaching Program

    Science.gov (United States)

    Brownlee, Jo; Petriwskyj, Anne; Thorpe, Karen; Stacey, Phillip; Gibson, Megan

    2011-01-01

    This study investigated changes in pre-service teachers' personal epistemologies as they engaged in an integrated teaching program. Personal epistemology refers to individual beliefs about the nature of knowing and knowledge and has been shown to influence teaching practice. An integrated approach to teaching, based on both an "implicit"…

  16. A Critical Agency Network Model for Building an Integrated Outreach Program

    Science.gov (United States)

    Kiyama, Judy Marquez; Lee, Jenny J.; Rhoades, Gary

    2012-01-01

    This study considers a distinct case of a college outreach program that integrates student affairs staff, academic administrators, and faculty across campus. The authors find that social networks and critical agency help to understand the integration of these various professionals and offer a critical agency network model of enacting change.…

  17. Wave of the Future?: Integrating IR, Outcomes Assessment, Planning, Program Review, and Accreditation

    Science.gov (United States)

    Leimer, Christina

    2010-01-01

    Integrating institutional research, outcomes assessment, program review, strategic planning, and accreditation can be a powerful means of creating a culture of evidence-based decision making and continuous improvement. This study examined how this "integrated" model is organized in practice, how such offices began, why this approach was chosen,…

  18. Enhancing creative problem solving in an integrated visual art and geometry program: A pilot study

    NARCIS (Netherlands)

    Schoevers, E.M.; Kroesbergen, E.H.; Pitta-Pantazi, D.

    2017-01-01

    This article describes a new pedagogical method, an integrated visual art and geometry program, which has the aim to increase primary school students' creative problem solving and geometrical ability. This paper presents the rationale for integrating visual art and geometry education. Furthermore

  19. Integrated predictive maintenance program vibration and lube oil analysis: Part I - history and the vibration program

    Energy Technology Data Exchange (ETDEWEB)

    Maxwell, H.

    1996-12-01

    This paper is the first of two papers which describe the Predictive Maintenance Program for rotating machines at the Palo Verde Nuclear Generating Station. The organization has recently been restructured and significant benefits have been realized by the interaction, or {open_quotes}synergy{close_quotes} between the Vibration Program and the Lube Oil Analysis Program. This paper starts with the oldest part of the program - the Vibration Program and discusses the evolution of the program to its current state. The {open_quotes}Vibration{close_quotes} view of the combined program is then presented.

  20. The Identification, Implementation, and Evaluation of Critical User Interface Design Features of Computer-Assisted Instruction Programs in Mathematics for Students with Learning Disabilities

    Science.gov (United States)

    Seo, You-Jin; Woo, Honguk

    2010-01-01

    Critical user interface design features of computer-assisted instruction programs in mathematics for students with learning disabilities and corresponding implementation guidelines were identified in this study. Based on the identified features and guidelines, a multimedia computer-assisted instruction program, "Math Explorer", which delivers…

  1. Let's get technical: Enhancing program evaluation through the use and integration of internet and mobile technologies.

    Science.gov (United States)

    Materia, Frank T; Miller, Elizabeth A; Runion, Megan C; Chesnut, Ryan P; Irvin, Jamie B; Richardson, Cameron B; Perkins, Daniel F

    2016-06-01

    Program evaluation has become increasingly important, and information on program performance often drives funding decisions. Technology use and integration can help ease the burdens associated with program evaluation by reducing the resources needed (e.g., time, money, staff) and increasing evaluation efficiency. This paper reviews how program evaluators, across disciplines, can apply internet and mobile technologies to key aspects of program evaluation, which consist of participant registration, participant tracking and retention, process evaluation (e.g., fidelity, assignment completion), and outcome evaluation (e.g., behavior change, knowledge gain). In addition, the paper focuses on the ease of use, relative cost, and fit with populations. An examination on how these tools can be integrated to enhance data collection and program evaluation is discussed. Important limitations of and considerations for technology integration, including the level of technical skill, cost needed to integrate various technologies, data management strategies, and ethical considerations, are highlighted. Lastly, a case study of technology use in an evaluation conducted by the Clearinghouse for Military Family Readiness at Penn State is presented and illustrates how technology integration can enhance program evaluation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Social Skill Training in an Integrated Preschool Program

    Science.gov (United States)

    Guglielmo, Hindi M.; Tryon, Georgiana Shick

    2001-01-01

    This study examined the effectiveness of a commercially available social skills training program plus classroom reinforcement for use with preschoolers with developmental delays. Two groups of 19 participants each received either the combined treatment package or classroom reinforcement of target behaviors only. An additional 20 participants…

  3. Integrating Research into an Undergraduate Family Sciences Program

    Science.gov (United States)

    Khelifa, Maher; Sonleitner, Nancy; Wooldridge, Deborah; Mayers, Gloysis

    2004-01-01

    The authors report the outcomes of introducing undergraduate research to family science majors at Zayed University, United Arab Emirates. The program has enriched students' educational experiences and has had tangible benefits. In addition to acquiring research skills, students improved in critical analysis, originality, independent learning,…

  4. 76 FR 34385 - Program Integrity: Gainful Employment-Debt Measures

    Science.gov (United States)

    2011-06-13

    ... unprecedented public engagement is stronger regulations that (1) Are based on careful consideration of both the.... Programs that offer a rewarding education at an affordable price will prosper, and institutions will... Engineering Institution, Washington, DC, who testified that ``the purely material rewards of continued...

  5. Efficiency of Social Studies Integrated Character Education Program

    Science.gov (United States)

    Katilmis, Ahmet; Eksi, Halil; Ozturk, Cemil

    2011-01-01

    In this research, it is aimed to find out (i) the efficiency of a character education program based on overt values of Turkish 7th grade social studies lesson, and (ii) its hidden effects on the academic success. This research employed a semi-experimental design with pre-test, post-test and control group For this research primarily character…

  6. How to Integrate International Financial Reporting Standards into Accounting Programs

    Science.gov (United States)

    Singer, Robert A.

    2012-01-01

    It is expected the SEC will require U.S. domestic companies to prepare and file their annual 10Ks in accordance with international financial reporting standards (IFRS) by 2016. Given the probability that the FASB-IASB convergence project (i.e., Norwalk Agreement) will continue subsequent to mandatory adoption, US accounting programs will be…

  7. Integrated Data Collection Analysis (IDCA) Program - KClO3/Dodecane Mixture

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorenson, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Shelley, Timothy J. [Air Force Research Lab. (AFRL), Tyndall AFB, FL (United States); Whinnery, LeRoy L. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2011-05-23

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small-Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of a mixture of KClO3 and dodecane—KClO3/dodecane mixture. This material was selected because of the challenge of performing SSST testing of a mixture of solid and liquid materials. The mixture was found to: 1) be more sensitive to impact than RDX, and PETN, 2) less sensitive to friction than PETN, and 3) less sensitive to spark than RDX. The thermal analysis showed little or no exothermic features suggesting that the dodecane volatilized at low temperatures. A prominent endothermic feature was observed assigned to melting of KClO3. This effort, funded by the Department of Homeland Security (DHS), ultimately will put the issues of safe handling of these materials in perspective with standard military explosives. The study is adding SSST testing results for a broad suite of different HMEs to the literature. Ultimately the study has the potential to suggest new guidelines and methods and possibly establish the SSST testing accuracies needed to develop safe handling practices for HMEs. Each participating testing laboratory uses identical test materials and preparation methods wherever possible. Note, however, the test procedures differ among the laboratories. The results are compared among the laboratories and then compared to historical data from various sources. The testing performers involved for the KClO3/dodecane mixture are Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), and Indian Head Division, Naval Surface Warfare Center, (NSWC IHD). These tests are conducted as a proficiency study in order to establish some consistency in test protocols, procedures, and experiments and to understand

  8. Generalization of special features of boundary element method realization in Ukrainian computer-aided programming systems

    OpenAIRE

    Korobanov, Yurii M.; Lishchuk, Ohnieslav M.; Lishchuk, Ivan M.

    2014-01-01

    The generalization of theoretical bases for engineering calculations of ship structures in the Ukrainian computer-aided design systems is performed. The mathematical base of the boundary elements method is set out; the boundary integral equation is presented. The method of fictitious loads is considered as the basis of ship structures calculation realization.

  9. The effectiveness and cost-effectiveness of an integrated cardiometabolic risk assessment and treatment program in primary care (the INTEGRATE study).

    NARCIS (Netherlands)

    Stol, D.; Badenbroek, I.; Hollander, M.; Nielen, M.; Schellevis, F.; Wit, N. de

    2014-01-01

    The effectiveness and cost-effectiveness of an integrated cardiometabolic risk assessment and treatment program in primary care (the INTEGRATE study): a stepped-wedge randomized controlled trial protocol. Rationale: The increasing prevalence of cardiometabolic disease (CMD), including cardiovascular

  10. An Examination of the Feasibility of Integrating Motivational Interviewing Techniques into FCS Cooperative Extension Programming

    Science.gov (United States)

    Radunovich, Heidi Liss; Ellis, Sarah; Spangler, Taylor

    2017-01-01

    Demonstrating program impact through behavior change is critical for the continued success of Family and Consumer Sciences (FCS) Cooperative Extension programming. However, the literature suggests that simply providing information to participants does not necessarily lead to behavior change. This study pilot tested the integration of Motivational…

  11. Integrated Program on Malaria in sub-Saharan Africa (IPMA) : Call ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Integrated Program on Malaria in sub-Saharan Africa (IPMA) will offer a shared and synergistic approach to existing malaria control programs. It will do so by supporting research aimed at understanding the complex societal and environmental dynamics affecting malaria in the region, and testing interventions that ...

  12. Programming of endogenous and exogenous saccades: Evidence for a competitive integration model

    NARCIS (Netherlands)

    Godijn, R.J.; Theeuwes, J.

    2002-01-01

    Participant's were required to make a saccade to a uniquely colored target while ignoring the presentation of an onset distractor. The results provide evidence for a competitive integration model of saccade programming that assumes endogenous and exogenous saccades are programmed in a common saccade

  13. School-Based Childhood Sexual Abuse Prevention Programs: An Integrative Review

    Science.gov (United States)

    Fryda, Candice M.; Hulme, Polly A.

    2015-01-01

    One prevention strategy for childhood sexual abuse (CSA) involves educational programs delivered to children in the school environment. The purpose of this integrative literature review was to determine the state of the science on school-based CSA prevention programs. The authors extracted data from 26 articles that fit inclusion criteria to…

  14. Shifting Views: Exploring the Potential for Technology Integration in Early Childhood Education Programs

    Science.gov (United States)

    Dietze, Beverlie; Kashin, Diane

    2013-01-01

    Using technology with children in play-based early learning programs creates questions for some within the Early Childhood Education (ECE) community. This paper presents how two faculty who teach in ECE-related degree programs integrated educational technology into their teaching pedagogy as a way to model to their students how it can be used to…

  15. Partnerships and Learning Communities in Work-Integrated Learning: Designing a Community Services Student Placement Program

    Science.gov (United States)

    Harris, Lisa; Jones, Martyn; Coutts, Sally

    2010-01-01

    The paper describes and analyses the design and implementation of a higher education student placement program in the community services sector. Principally ideas about partnerships and social learning informed the design. The placement program represents a significant innovation in work-integrated learning, achieved through collaboration between…

  16. Integrating Reproductive Health Services Into Intimate Partner and Sexual Violence Victim Service Programs.

    Science.gov (United States)

    Gmelin, Theresa; Raible, Claire A; Dick, Rebecca; Kukke, Surabhi; Miller, Elizabeth

    2017-12-01

    This study assessed the feasibility of integrating reproductive health services into intimate partner violence/sexual violence (IPV/SV) programs. After a training for victim service agencies on integration of health services, we conducted semistructured interviews with IPV/SV program leadership. Leadership reported advocates were more likely to recognize the need to refer clients to health services, and revealed challenges operationalizing partnerships with health care centers. Training to integrate basic health assessment into victim services may be one way to address women's urgent health needs. Formal partnership agreements, protocols to facilitate referrals, and opportunities to cross-train are needed to nurture these cross-sector collaborations.

  17. Syntax-Directed Editing: Towards Integrated Programming Environments

    Science.gov (United States)

    1982-03-01

    Center, June, 1979. Stallman , Richard M. EMACS, the extensible, customizable, self documenting display editor. In Proceedings of the ACM SIGPLAN/SIGOA...display-oriented text editors such as EMACS [ Stallman 61] and UNixtm EMACS [Gosling 81a]. Within the programming task, these text editors are still...EMACS [ Stallman 81]. To experiment with these decisions and to provide the flexibility necessary for different kinds of users, both forms are

  18. Making automated computer program documentation a feature of total system design

    Science.gov (United States)

    Wolf, A. W.

    1970-01-01

    It is pointed out that in large-scale computer software systems, program documents are too often fraught with errors, out of date, poorly written, and sometimes nonexistent in whole or in part. The means are described by which many of these typical system documentation problems were overcome in a large and dynamic software project. A systems approach was employed which encompassed such items as: (1) configuration management; (2) standards and conventions; (3) collection of program information into central data banks; (4) interaction among executive, compiler, central data banks, and configuration management; and (5) automatic documentation. A complete description of the overall system is given.

  19. Trauma Center Based Youth Violence Prevention Programs: An Integrative Review.

    Science.gov (United States)

    Mikhail, Judy Nanette; Nemeth, Lynne Sheri

    2016-12-01

    Youth violence recidivism remains a significant public health crisis in the United States. Violence prevention is a requirement of all trauma centers, yet little is known about the effectiveness of these programs. Therefore, this systematic review summarizes the effectiveness of trauma center-based youth violence prevention programs. A systematic review of articles from MEDLINE, CINAHL, and PsychINFO databases was performed to identify eligible control trials or observational studies. Included studies were from 1970 to 2013, describing and evaluating an intervention, were trauma center based, and targeted youth injured by violence (tertiary prevention). The social ecological model provided the guiding framework, and findings are summarized qualitatively. Ten studies met eligibility requirements. Case management and brief intervention were the primary strategies, and 90% of the studies showed some improvement in one or more outcome measures. These results held across both social ecological level and setting: both emergency department and inpatient unit settings. Brief intervention and case management are frequent and potentially effective trauma center-based violence prevention interventions. Case management initiated as an inpatient and continued beyond discharge was the most frequently used intervention and was associated with reduced rearrest or reinjury rates. Further research is needed, specifically longitudinal studies using experimental designs with high program fidelity incorporating uniform direct outcome measures. However, this review provides initial evidence that trauma centers can intervene with the highest of risk patients and break the youth violence recidivism cycle. © The Author(s) 2015.

  20. Integrating research and education into clinical practice: the multi-organ transplant student research training program.

    Science.gov (United States)

    Famure, Olusegun; Li, Anna; Ross, Heather; Kim, S Joseph

    2012-01-01

    Given the increased student interest in health research and the need to implement health research initiatives, the Multi-Organ Transplant Student Research Training Program provides student trainees with the opportunity to contribute to health research initiatives in transplant care. Program quality initiatives achieved include the development of a clinical research database, knowledge exchange, performance measurement tools, and health research projects. The program promotes collaboration between academic and healthcare institutions to integrate research and education into clinical practice.

  1. DITTY - a computer program for calculating population dose integrated over ten thousand years

    Energy Technology Data Exchange (ETDEWEB)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.

    1986-03-01

    The computer program DITTY (Dose Integrated Over Ten Thousand Years) was developed to determine the collective dose from long term nuclear waste disposal sites resulting from the ground-water pathways. DITTY estimates the time integral of collective dose over a ten-thousand-year period for time-variant radionuclide releases to surface waters, wells, or the atmosphere. This document includes the following information on DITTY: a description of the mathematical models, program designs, data file requirements, input preparation, output interpretations, sample problems, and program-generated diagnostic messages.

  2. Program of Adaptation Assistance in Foster Families and Particular Features of Its Implementation

    Science.gov (United States)

    Zakirova, Venera G.; Gaysina, Guzel I.; Zhumabaeva, Asia

    2015-01-01

    Relevance of the problem stated in the article, conditioned by the fact that the successful adaptation of orphans in a foster family requires specialized knowledge and skills, as well as the need of professional support. Therefore, this article aims at substantiation of the effectiveness of the developed pilot program psycho-pedagogical support of…

  3. Integrated care programs for patients with psychological comorbidity: A systematic review and meta-analysis.

    Science.gov (United States)

    Lemmens, Lidwien C; Molema, Claudia C M; Versnel, Nathalie; Baan, Caroline A; de Bruin, Simone R

    2015-12-01

    Presently, little is known about the characteristics and impact of integrated care programs for patients with psychological comorbidity. The aim was to provide an overview of these integrated care programs and their effectiveness. Systematic literature review including papers published between 1995 and 2014. An integrated care program had to consist of interventions related to at least two out of the six components of the Chronic Care Model. Programs had to address patients with psychological comorbidity, which is a psychological disease next to a somatic chronic disease. A meta-analysis was performed on depression treatment response and a best evidence synthesis was performed on other outcomes. Ten programs were identified, which mostly addressed comorbid depression and consisted of interventions related to three to five components of the Chronic Care Model. Meta-analysis showed significantly higher odds for depression treatment response for patients receiving integrated care (OR: 2.49, 95%CI [1.66-3.75]). Best evidence synthesis suggested moderate evidence for cost-effectiveness and for a beneficial effect on patient satisfaction and emotional well-being. Insufficient evidence was found for a beneficial effect on health-related quality of life, medication adherence, Hb1Ac levels and mortality. There are few studies evaluating integrated care programs for patients with psychological comorbidity. Although these studies suggest that integrated care programs could positively affect several patient outcomes and could be cost-effective, additional studies are recommended to further assess the value of integrated care for this patient group. This is especially important since the number of people with psychological comorbidity is rising. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Unpacking vertical and horizontal integration: childhood overweight/obesity programs and planning, a Canadian perspective.

    Science.gov (United States)

    Maclean, Lynne M; Clinton, Kathryn; Edwards, Nancy; Garrard, Michael; Ashley, Lisa; Hansen-Ketchum, Patti; Walsh, Audrey

    2010-05-17

    Increasingly, multiple intervention programming is being understood and implemented as a key approach to developing public health initiatives and strategies. Using socio-ecological and population health perspectives, multiple intervention programming approaches are aimed at providing coordinated and strategic comprehensive programs operating over system levels and across sectors, allowing practitioners and decision makers to take advantage of synergistic effects. These approaches also require vertical and horizontal (v/h) integration of policy and practice in order to be maximally effective. This paper examines v/h integration of interventions for childhood overweight/obesity prevention and reduction from a Canadian perspective. It describes the implications of v/h integration for childhood overweight and obesity prevention, with examples of interventions where v/h integration has been implemented. An application of a conceptual framework for structuring v/h integration of an overweight/obesity prevention initiative is presented. The paper concludes with a discussion of the implications of vertical/horizontal integration for policy, research, and practice related to childhood overweight and obesity prevention multiple intervention programs. Both v/h integration across sectors and over system levels are needed to fully support multiple intervention programs of the complexity and scope required by obesity issues. V/h integration requires attention to system structures and processes. A conceptual framework is needed to support policy alignment, multi-level evaluation, and ongoing coordination of people at the front lines of practice. Using such tools to achieve integration may enhance sustainability, increase effectiveness of prevention and reduction efforts, decrease stigmatization, and lead to new ways to relate the environment to people and people to the environment for better health for children.

  5. Unpacking vertical and horizontal integration: childhood overweight/obesity programs and planning, a Canadian perspective

    Directory of Open Access Journals (Sweden)

    Ashley Lisa

    2010-05-01

    Full Text Available Abstract Background Increasingly, multiple intervention programming is being understood and implemented as a key approach to developing public health initiatives and strategies. Using socio-ecological and population health perspectives, multiple intervention programming approaches are aimed at providing coordinated and strategic comprehensive programs operating over system levels and across sectors, allowing practitioners and decision makers to take advantage of synergistic effects. These approaches also require vertical and horizontal (v/h integration of policy and practice in order to be maximally effective. Discussion This paper examines v/h integration of interventions for childhood overweight/obesity prevention and reduction from a Canadian perspective. It describes the implications of v/h integration for childhood overweight and obesity prevention, with examples of interventions where v/h integration has been implemented. An application of a conceptual framework for structuring v/h integration of an overweight/obesity prevention initiative is presented. The paper concludes with a discussion of the implications of vertical/horizontal integration for policy, research, and practice related to childhood overweight and obesity prevention multiple intervention programs. Summary Both v/h integration across sectors and over system levels are needed to fully support multiple intervention programs of the complexity and scope required by obesity issues. V/h integration requires attention to system structures and processes. A conceptual framework is needed to support policy alignment, multi-level evaluation, and ongoing coordination of people at the front lines of practice. Using such tools to achieve integration may enhance sustainability, increase effectiveness of prevention and reduction efforts, decrease stigmatization, and lead to new ways to relate the environment to people and people to the environment for better health for children.

  6. Integrating electron microscopy into nanoscience and materials engineering programs

    Science.gov (United States)

    Cormia, Robert D.; Oye, Michael M.; Nguyen, Anh; Skiver, David; Shi, Meng; Torres, Yessica

    2014-10-01

    Preparing an effective workforce in high technology is the goal of both academic and industry training, and has been the engine that drives innovation and product development in the United States for over a century. During the last 50 years, technician training has comprised a combination of two-year academic programs, internships and apprentice training, and extensive On-the-Job Training (OJT). Recently, and especially in Silicon Valley, technicians have four-year college degrees, as well as relevant hands-on training. Characterization in general, and microscopy in particular, is an essential tool in process development, manufacturing and QA/QC, and failure analysis. Training for a broad range of skills and practice is challenging, especially for community colleges. Workforce studies (SRI/Boeing) suggest that even four year colleges often do not provide the relevant training and experience in laboratory skills, especially design of experiments and analysis of data. Companies in high-tech further report difficulty in finding skilled labor, especially with industry specific experience. Foothill College, in partnership with UCSC, SJSU, and NASA-Ames, has developed a microscopy training program embedded in a research laboratory, itself a partnership between university and government, providing hands-on experience in advanced instrumentation, experimental design and problem solving, with real-world context from small business innovators, in an environment called `the collaboratory'. The program builds on AFM-SEM training at Foothill, and provides affordable training in FE-SEM and TEM through a cost recovery model. In addition to instrument and engineering training, the collaboratory also supports academic and personal growth through a multiplayer social network of students, faculty, researchers, and innovators.

  7. An integrative machine learning strategy for improved prediction of essential genes in Escherichia coli metabolism using flux-coupled features.

    Science.gov (United States)

    Nandi, Sutanu; Subramanian, Abhishek; Sarkar, Ram Rup

    2017-07-25

    Prediction of essential genes helps to identify a minimal set of genes that are absolutely required for the appropriate functioning and survival of a cell. The available machine learning techniques for essential gene prediction have inherent problems, like imbalanced provision of training datasets, biased choice of the best model for a given balanced dataset, choice of a complex machine learning algorithm, and data-based automated selection of biologically relevant features for classification. Here, we propose a simple support vector machine-based learning strategy for the prediction of essential genes in Escherichia coli K-12 MG1655 metabolism that integrates a non-conventional combination of an appropriate sample balanced training set, a unique organism-specific genotype, phenotype attributes that characterize essential genes, and optimal parameters of the learning algorithm to generate the best machine learning model (the model with the highest accuracy among all the models trained for different sample training sets). For the first time, we also introduce flux-coupled metabolic subnetwork-based features for enhancing the classification performance. Our strategy proves to be superior as compared to previous SVM-based strategies in obtaining a biologically relevant classification of genes with high sensitivity and specificity. This methodology was also trained with datasets of other recent supervised classification techniques for essential gene classification and tested using reported test datasets. The testing accuracy was always high as compared to the known techniques, proving that our method outperforms known methods. Observations from our study indicate that essential genes are conserved among homologous bacterial species, demonstrate high codon usage bias, GC content and gene expression, and predominantly possess a tendency to form physiological flux modules in metabolism.

  8. UniCarbKB: New database features for integrating glycan structure abundance, compositional glycoproteomics data, and disease associations.

    Science.gov (United States)

    Campbell, Matthew P; Packer, Nicolle H

    2016-08-01

    UniCarbKB aims to provide a resource for the representation of mammalian glycobiology knowledge by providing a curated database of structural and experimental data, supported by a web application that allows users to easily find and view richly annotated information. The database comprises two levels of annotation (i) global-specific data of oligosaccharides released and characterised from single purified glycoproteins and (ii) information pertaining to site-specific glycan heterogeneity. Additional, contextual information is provided including structural, bibliographic, and taxonomic information for each entry. Since the launch of UniCarbKB in 2012, we have continued to improve the organisation of our data model. Recently, we have extended our pipeline to collate structural and abundance changes of oligosaccharides in different human disease states and experimental models to extend our coverage of the human glycome. In this manuscript, we demonstrate the capability of UniCarbKB to store and query relative glycan abundance data using a set of published colorectal and prostate cancer cell lines as examples. Furthermore, we outline our strategy for managing large-scale glycoproteomics data, site-specific and glycan compositional data, and how this information is adding value to UniCarbKB. Finally, we summarise our efforts to improve the efficient representation of disease terms and associated changes in glycan heterogeneity by integrating the Disease Ontology. Updates and improvements to UniCarbKB have introduced unique features for storing and displaying glycosylation features of mammalian glycoproteins. The integration of site-specific glycosylation data obtained from large-scale glycoproteomics and introduction of cell line studies will improve the analysis of glycoproteins and entire glycomes. Continuing advancements in analytical technologies and new data types are advancing disease-related glycomics. It is increasingly necessary to ensure all the data are

  9. Socio-economic, epidemiological and geographic features based on GIS-integrated mapping to identify malarial hotspots.

    Science.gov (United States)

    Qayum, Abdul; Arya, Rakesh; Kumar, Pawan; Lynn, Andrew M

    2015-05-07

    Malaria is a major health problem in the tropical and subtropical world. In India, 95% of the population resides in malaria endemic regions and it is major public health problem in most parts of the country. The present work has developed malaria maps by integrating socio-economic, epidemiology and geographical dimensions of three eastern districts of Uttar Pradesh, India. The area has been studied in each dimension separately, and later integrated to find a list of vulnerable pockets/villages, called as malarial hotspots. The study has been done at village level. Seasonal variation of malaria, comparison of epidemiology indices and progress of the medical facility were studied. Ten independent geographical information system (GIS) maps of socio-economic aspects (population, child population, literacy, and work force participation), epidemiology (annual parasitic index (API) and slides collected and examined) and geographical features (settlement, forest cover, water bodies, rainfall, relative humidity, and temperature) were drawn and studied. These maps were overlaid based on computed weight matrix to find malarial hotspot. It was found that the studied dimensions were inter-weaving factors for malaria epidemic and closely affected malaria situations as evidenced from the obtained correlation matrix. The regions with water logging, high rainfall and proximity to forest, along with poor socio-economic conditions, are primarily hotspot regions. The work is presented through a series of GIS maps, tables, figures and graphs. A total of 2,054 out of 8,973 villages studied were found to be malarial hotspots and consequently suggestions were made to the concerned government malaria offices. With developing technology, information tools such as GIS, have captured almost every field of scientific research especially of vector-borne diseases, such as malaria. Malarial mapping enables easy update of information and effortless accessibility of geo-referenced data to policy

  10. Sensitivity Analysis of the Integrated Medical Model for ISS Programs

    Science.gov (United States)

    Goodenow, D. A.; Myers, J. G.; Arellano, J.; Boley, L.; Garcia, Y.; Saile, L.; Walton, M.; Kerstman, E.; Reyes, D.; Young, M.

    2016-01-01

    Sensitivity analysis estimates the relative contribution of the uncertainty in input values to the uncertainty of model outputs. Partial Rank Correlation Coefficient (PRCC) and Standardized Rank Regression Coefficient (SRRC) are methods of conducting sensitivity analysis on nonlinear simulation models like the Integrated Medical Model (IMM). The PRCC method estimates the sensitivity using partial correlation of the ranks of the generated input values to each generated output value. The partial part is so named because adjustments are made for the linear effects of all the other input values in the calculation of correlation between a particular input and each output. In SRRC, standardized regression-based coefficients measure the sensitivity of each input, adjusted for all the other inputs, on each output. Because the relative ranking of each of the inputs and outputs is used, as opposed to the values themselves, both methods accommodate the nonlinear relationship of the underlying model. As part of the IMM v4.0 validation study, simulations are available that predict 33 person-missions on ISS and 111 person-missions on STS. These simulated data predictions feed the sensitivity analysis procedures. The inputs to the sensitivity procedures include the number occurrences of each of the one hundred IMM medical conditions generated over the simulations and the associated IMM outputs: total quality time lost (QTL), number of evacuations (EVAC), and number of loss of crew lives (LOCL). The IMM team will report the results of using PRCC and SRRC on IMM v4.0 predictions of the ISS and STS missions created as part of the external validation study. Tornado plots will assist in the visualization of the condition-related input sensitivities to each of the main outcomes. The outcomes of this sensitivity analysis will drive review focus by identifying conditions where changes in uncertainty could drive changes in overall model output uncertainty. These efforts are an integral

  11. Integrated Risk and Knowledge Management Program -- IRKM-P

    Science.gov (United States)

    Lengyel, David M.

    2009-01-01

    The NASA Exploration Systems Mission Directorate (ESMD) IRKM-P tightly couples risk management and knowledge management processes and tools to produce an effective "modern" work environment. IRKM-P objectives include: (1) to learn lessons from past and current programs (Apollo, Space Shuttle, and the International Space Station); (2) to generate and share new engineering design, operations, and management best practices through preexisting Continuous Risk Management (CRM) procedures and knowledge-management practices; and (3) to infuse those lessons and best practices into current activities. The conceptual framework of the IRKM-P is based on the assumption that risks highlight potential knowledge gaps that might be mitigated through one or more knowledge management practices or artifacts. These same risks also serve as cues for collection of knowledge particularly, knowledge of technical or programmatic challenges that might recur.

  12. Gore-Mbeki Binational Commission integrated housing program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report documents the work done under Grant DE-FG36-97GO10209, Innovative Renewable Energy Technology Transfer Program. PEER Consultants, PC, and its subcontractor, PEER Africa (Pty.) Ltd., received an $88,000.00 grant to plan and build two energy efficient homes in the black township of Gugulethu in Cape Town, South Africa. These demonstration homes were given to the people of South Africa as a gesture of goodwill by the US government as part of the Gore-Mbeki Binational Commission (BNC) agreements and cooperation. The BNC is the term used to describe the agreement to work together by the US and the South African governments for economic development of South Africa in the areas of energy, commerce, agriculture, housing, and transportation. The BNC was formed in 1995. This project under the auspices of the BNC started in September 1996. The DOE-funded portion was performed between January 11, 1997 and February 28, 1997.

  13. Sustainability Science Educational Program as Integrated Disciplinary Education : Practices and Lessons at Osaka University

    Science.gov (United States)

    Uwasu, Michinori; Shimoda, Yoshiyuki

    As global threats such as climate change and economic crisis have been emerging, the demand for the establishment of integrated disciplinary education programs is increasing. The Research Institute for Sustainability Science (RISS) at Osaka University started a new program on sustainability in October 2007. The RISS program addresses the ways to utilize knowledge effectively to understand the dynamic interactions between nature and human society. This paper first overviews the RISS Program for Sustainability Science. The paper then discusses the main problems as well as attempts and efforts to challenge those issues. Although issues including institutional barriers and faculty development yet remain in promoting integrated education, the RISS program functions as a platform to disseminate the idea of sustainability science across the university.

  14. Processes and Outcomes from a Medical Student Research Training Program in Integrative, Complementary, and Alternative Medicine.

    Science.gov (United States)

    Dicianno, Brad E; Glick, Ronald M; Sowa, Gwendolyn A; Boninger, Michael L

    2016-10-01

    In response to the growing need to train a new generation of clinician scientists, a research program was developed to train medical students in integrative, complementary, and alternative medicine (ICAM) research early in their careers. A total of 25 students (100%) successfully completed a 10-week program. Students reported significantly increased levels of knowledge in all 7 integrative, complementary, and alternative medicine topics at the conclusion of the program. All students presented their work at one or more local research symposia. In addition, the average number of quality research outputs, which included manuscripts, awards, and abstracts presented at national and international meetings, was 1.5 per student, which exceeded benchmarks based on prior program outcomes. Results from this program may be useful when planning larger or longer-term projects aimed at attracting physicians who will become our next generation of academicians, researchers, and healers.

  15. Human health risk comparisons for environmental management baseline program and integration opportunities (discussion draft)

    Energy Technology Data Exchange (ETDEWEB)

    Eide, S.A.; Jones, J.L.; Wierman, T.E.

    1998-02-01

    This report documents the process and results of human health risk assessments of the US Department of Energy (DOE) complex-wide programs for high-level waste, transuranic waste, low-level waste, mixed low-level waste, and spent nuclear fuel. The DOE baseline programs and alternatives for these five material types were characterized by disposition maps (system flow diagrams) and supporting information in the May 1997 report A Contractor Report to the Department of Energy on Environmental Baseline Programs and Integration Opportunities (Discussion Draft). Risk analyses were performed using the Simplified Risk Model (SRM), developed to support DOE Environmental Management (EM) integration studies. The SRM risk analyses consistently and comprehensively cover the entire programs for the five material types, from initial storage through final disposition. Risk results are presented at several levels: DOE complex-wide, material type program, individual DOE sites, and DOE site activities.

  16. Functional Integration of mRNA Translational Control Programs

    Directory of Open Access Journals (Sweden)

    Melanie C. MacNicol

    2015-07-01

    Full Text Available Regulated mRNA translation plays a key role in control of cell cycle progression in a variety of physiological and pathological processes, including in the self-renewal and survival of stem cells and cancer stem cells. While targeting mRNA translation presents an attractive strategy for control of aberrant cell cycle progression, mRNA translation is an underdeveloped therapeutic target. Regulated mRNAs are typically controlled through interaction with multiple RNA binding proteins (RBPs but the mechanisms by which the functions of distinct RBPs bound to a common target mRNA are coordinated are poorly understood. The challenge now is to gain insight into these mechanisms of coordination and to identify the molecular mediators that integrate multiple, often conflicting, inputs. A first step includes the identification of altered mRNA ribonucleoprotein complex components that assemble on mRNAs bound by multiple, distinct RBPs compared to those recruited by individual RBPs. This review builds upon our knowledge of combinatorial control of mRNA translation during the maturation of oocytes from Xenopus laevis, to address molecular strategies that may mediate RBP diplomacy and conflict resolution for coordinated control of mRNA translational output. Continued study of regulated ribonucleoprotein complex dynamics promises valuable new insights into mRNA translational control and may suggest novel therapeutic strategies for the treatment of disease.

  17. Aging Evaluation Programs for Jet Transport Aircraft Structural Integrity

    Directory of Open Access Journals (Sweden)

    Borivoj Galović

    2012-10-01

    Full Text Available The paper deals with criteria and procedures in evaluationof timely preventive maintenance recommendations that willsupport continued safe operation of aging jet transports untiltheir retirement from service. The active service life of commercialaircraft has increased in recent years as a result of low fuelcost, and increasing costs and delivery times for fleet replacements.Air transport industry consensus is that older jet transportswill continue in service despite anticipated substantial increasesin required maintenance. Design concepts, supportedby testing, have worked well due to the system that is used to ensureflying safety. Continuing structural integrity by inspectionand overhaul recommendation above the level contained inmaintenance and service bulletins is additional requirement, insuch cases. Airplane structural safety depends on the performanceof all participants in the system and the responsibility forsafety cannot be delegated to a single participant. This systemhas three major participants: the manufacturers who design,build and support airplanes in service, the airlines who operate,inspect and mantain airplanes and the airworthiness authoritieswho establish rules and regulations, approve the design andpromote airline maintenance performance.

  18. The biology of lysine acetylation integrates transcriptional programming and metabolism

    Directory of Open Access Journals (Sweden)

    Mujtaba Shiraz

    2011-03-01

    Full Text Available Abstract The biochemical landscape of lysine acetylation has expanded from a small number of proteins in the nucleus to a multitude of proteins in the cytoplasm. Since the first report confirming acetylation of the tumor suppressor protein p53 by a lysine acetyltransferase (KAT, there has been a surge in the identification of new, non-histone targets of KATs. Added to the known substrates of KATs are metabolic enzymes, cytoskeletal proteins, molecular chaperones, ribosomal proteins and nuclear import factors. Emerging studies demonstrate that no fewer than 2000 proteins in any particular cell type may undergo lysine acetylation. As described in this review, our analyses of cellular acetylated proteins using DAVID 6.7 bioinformatics resources have facilitated organization of acetylated proteins into functional clusters integral to cell signaling, the stress response, proteolysis, apoptosis, metabolism, and neuronal development. In addition, these clusters also depict association of acetylated proteins with human diseases. These findings not only support lysine acetylation as a widespread cellular phenomenon, but also impel questions to clarify the underlying molecular and cellular mechanisms governing target selectivity by KATs. Present challenges are to understand the molecular basis for the overlapping roles of KAT-containing co-activators, to differentiate between global versus dynamic acetylation marks, and to elucidate the physiological roles of acetylated proteins in biochemical pathways. In addition to discussing the cellular 'acetylome', a focus of this work is to present the widespread and dynamic nature of lysine acetylation and highlight the nexus that exists between epigenetic-directed transcriptional regulation and metabolism.

  19. Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program

    Directory of Open Access Journals (Sweden)

    Charu Mehta

    2017-09-01

    Full Text Available Hematopoietic development requires the transcription factor GATA-2, and GATA-2 mutations cause diverse pathologies, including leukemia. GATA-2-regulated enhancers increase Gata2 expression in hematopoietic stem/progenitor cells and control hematopoiesis. The +9.5-kb enhancer activates transcription in endothelium and hematopoietic stem cells (HSCs, and its deletion abrogates HSC generation. The −77-kb enhancer activates transcription in myeloid progenitors, and its deletion impairs differentiation. Since +9.5−/− embryos are HSC deficient, it was unclear whether the +9.5 functions in progenitors or if GATA-2 expression in progenitors solely requires −77. We further dissected the mechanisms using −77;+9.5 compound heterozygous (CH mice. The embryonic lethal CH mutation depleted megakaryocyte-erythrocyte progenitors (MEPs. While the +9.5 suffices for HSC generation, the −77 and +9.5 must reside on one allele to induce MEPs. The −77 generated burst-forming unit-erythroid through the induction of GATA-1 and other GATA-2 targets. The enhancer circuits controlled signaling pathways that orchestrate a GATA factor-dependent blood development program.

  20. A Design Case Featuring the Graduate Design Studio at Indiana University Bloomington’s Human-Computer Interaction Design Program

    Directory of Open Access Journals (Sweden)

    Matthew Callison

    2011-01-01

    Full Text Available In this article the author illustrates the design of a physical space that was created to serve as a performance intervention for graduate students in the Human-Computer Interaction Design (HCId program in the School of Informatics, Indiana University Bloomington. Opened in Fall 2010, the HCId Graduate Design Studio was designed to help facilitate collaboration between students and faculty in the HCId Program. An effort was made to document the Studio and students working in the Studio over an extended period of time. The author visited the Design Studio a minimum of ten times between late January and late April 2011. Visits were conducted on different days of the week (Monday - Friday and at different times of the day to capture a variety of students and activity level in the Studio. In order to gain a perspective on the two distinct groups of students who utilize the Studio, interviews of graduate students from both the HCId Master of Science and Doctoral program were conducted. In addition interviews were conducted of two other important stakeholders, the HCId Program Director and the Director of Facilities for the School of Informatics, both of whom were heavily involved in the design of the Studio. Through faculty and student interviews, text descriptions, photographs, and audio and video recordings this article addresses the design features and their impact, both successful and unsuccessful, on student and faculty collaboration of the HCId Graduate Design Studio.

  1. Integration of a specific nutrition program into a comprehensive program of therapeutic education

    OpenAIRE

    Trolonge, Stanislas; Idier, Laetitia; Larroumet, Nicole; Lespinasse, Lucille; Capdepon, Laurence; Dos Reis, Sandra; Chauveau, Philippe

    2012-01-01

    Nutritional education strategies should be included in a multidisciplinary team for therapeutic education (TPE). We conduct a comprehensive program of therapeutic education for out-center hemodialysis patients. 5 education workshops were performed during dialysis sessions, every 15 days: Illness experience (psychologist), vascular access (nurses), medication management (pharmacist), nutrition management (dietitian) and final evaluation. A specific program of nutrition (EDAM project: Educat...

  2. Programming and Training Booklet 6: How to Integrate Programming and Training.

    Science.gov (United States)

    Peace Corps, Washington, DC. Information Collection and Exchange Div.

    This booklet, one of six that compose the Peace Corp's programming and training (P&T) guidelines, provides information and ideas on ways to increase each post's effectiveness through linking P&T. An introduction discusses the direct impact that P&T have on the success of each other, since, at the Peace Corps, programming drives…

  3. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Code Reference Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; K. J. Kvarfordt; S. T. Wood

    2006-07-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer. SAPHIRE is funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). The INL's primary role in this project is that of software developer. However, the INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users comprised of a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. SAPHIRE can be used to model a complex system’s response to initiating events, quantify associated damage outcome frequencies, and identify important contributors to this damage (Level 1 PRA) and to analyze containment performance during a severe accident and quantify radioactive releases (Level 2 PRA). It can be used for a PRA evaluating a variety of operating conditions, for example, for a nuclear reactor at full power, low power, or at shutdown conditions. Furthermore, SAPHIRE can be used to analyze both internal and external initiating events and has special features for ansforming models built for internal event analysis to models for external event analysis. It can also be used in a limited manner to quantify risk in terms of release consequences to both the public and the environment (Level 3 PRA). SAPHIRE includes a separate module called the Graphical Evaluation Module (GEM). GEM provides a highly specialized user interface with SAPHIRE that automates SAPHIRE process steps for evaluating operational events at commercial nuclear power plants. Using GEM, an analyst can estimate the risk associated with operational events in a very efficient and expeditious manner. This reference guide will introduce the SAPHIRE Version 7.0 software. A brief discussion of the purpose and history of the software is included along with

  4. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Code Reference Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; K. J. Kvarfordt; S. T. Wood

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer. SAPHIRE is funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). The INL's primary role in this project is that of software developer. However, the INL also plays an important role in technology transfer by interfacing and supporting SAPHIRE users comprised of a wide range of PRA practitioners from the NRC, national laboratories, the private sector, and foreign countries. SAPHIRE can be used to model a complex system’s response to initiating events, quantify associated damage outcome frequencies, and identify important contributors to this damage (Level 1 PRA) and to analyze containment performance during a severe accident and quantify radioactive releases (Level 2 PRA). It can be used for a PRA evaluating a variety of operating conditions, for example, for a nuclear reactor at full power, low power, or at shutdown conditions. Furthermore, SAPHIRE can be used to analyze both internal and external initiating events and has special features for transforming models built for internal event analysis to models for external event analysis. It can also be used in a limited manner to quantify risk in terms of release consequences to both the public and the environment (Level 3 PRA). SAPHIRE includes a separate module called the Graphical Evaluation Module (GEM). GEM provides a highly specialized user interface with SAPHIRE that automates SAPHIRE process steps for evaluating operational events at commercial nuclear power plants. Using GEM, an analyst can estimate the risk associated with operational events in a very efficient and expeditious manner. This reference guide will introduce the SAPHIRE Version 7.0 software. A brief discussion of the purpose and history of the software is included along with

  5. Integrated agriculture programs to address malnutrition in northern Malawi.

    Science.gov (United States)

    Kerr, Rachel Bezner; Chilanga, Emmanuel; Nyantakyi-Frimpong, Hanson; Luginaah, Isaac; Lupafya, Esther

    2016-11-28

    were some of the reasons that respondents named for changed gender norms. Participatory education that explicitly addresses hegemonic masculinities related to child nutrition, such as women's roles in child care, can begin to change dominant gender norms. Involving male leaders, participatory methods and integrating agriculture and food security concerns with nutrition appear to be key components in the context of agrarian communities.

  6. Integrated agriculture programs to address malnutrition in northern Malawi

    Directory of Open Access Journals (Sweden)

    Rachel Bezner Kerr

    2016-11-01

    agriculture and food security, alongside involving male leaders were some of the reasons that respondents named for changed gender norms. Conclusions Participatory education that explicitly addresses hegemonic masculinities related to child nutrition, such as women’s roles in child care, can begin to change dominant gender norms. Involving male leaders, participatory methods and integrating agriculture and food security concerns with nutrition appear to be key components in the context of agrarian communities.

  7. An integrative theory-driven framework for evaluating travel training programs.

    Science.gov (United States)

    Park, Chul Hyun; Welch, Eric W; Sriraj, P S

    2016-12-01

    Since the 1970s, travel training programs, which provide a short-term training to people with disabilities and older people to teach them independent travel skills required to use fixed-route transportation, have spread across the United States. But the authors note that currently, there is no integrative framework for evaluating the training programs, although it is crucial for improving program implementation and developing knowledge and theories related to travel training. Therefore, this research aims to build an integrative theory-driven evaluation framework of the programs on the basis of prior studies on travel training and the literature on program evaluation and learning and training theories. The framework considers (1) a wide range of key elements related to the delivery systems and outcomes of travel training; (2) diverse stakeholders that engage in designing, operating, and assessing travel training; and (3) the short-term, intermediate, and long-term outcomes of the programs. Based on the framework, the authors develop a flexible logic model for travel training programs to help scholars and practitioners design and conduct actual evaluation studies. Thus, this research is expected to make theoretical and practical contributions to theory-driven program evaluation and travel training programs. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Implementing preventive chemotherapy through an integrated National Neglected Tropical Disease Control Program in Mali.

    Directory of Open Access Journals (Sweden)

    Massitan Dembélé

    Full Text Available BACKGROUND: Mali is endemic for all five targeted major neglected tropical diseases (NTDs. As one of the five 'fast-track' countries supported with the United States Agency for International Development (USAID funds, Mali started to integrate the activities of existing disease-specific national control programs on these diseases in 2007. The ultimate objectives are to eliminate lymphatic filariasis, onchocerciasis and trachoma as public health problems and to reduce morbidity caused by schistosomiasis and soil-transmitted helminthiasis through regular treatment to eligible populations, and the specific objectives were to achieve 80% program coverage and 100% geographical coverage yearly. The paper reports on the implementation of the integrated mass drug administration and the lessons learned. METHODOLOGY/PRINCIPAL FINDINGS: The integrated control program was led by the Ministry of Health and coordinated by the national NTD Control Program. The drug packages were designed according to the disease endemicity in each district and delivered through various platforms to eligible populations involving the primary health care system. Treatment data were recorded and reported by the community drug distributors. After a pilot implementation of integrated drug delivery in three regions in 2007, the treatment for all five targeted NTDs was steadily scaled up to 100% geographical coverage by 2009, and program coverage has since been maintained at a high level: over 85% for lymphatic filariasis, over 90% for onchocerciasis and soil-transmitted helminthiasis, around 90% in school-age children for schistosomiasis, and 76-97% for trachoma. Around 10 million people have received one or more drug packages each year since 2009. No severe cases of adverse effects were reported. CONCLUSIONS/SIGNIFICANCE: Mali has scaled up the drug treatment to national coverage through integrated drug delivery involving the primary health care system. The successes and lessons

  9. Integrating information from disparate sources: the Walter Reed National Surgical Quality Improvement Program Data Transfer Project.

    Science.gov (United States)

    Nelson, Victoria; Nelson, Victoria Ruth; Li, Fiona; Green, Susan; Tamura, Tomoyoshi; Liu, Jun-Min; Class, Margaret

    2008-11-06

    The Walter Reed National Surgical Quality Improvement Program Data Transfer web module integrates with medical and surgical information systems, and leverages outside standards, such as the National Library of Medicine's RxNorm, to process surgical and risk assessment data. Key components of the project included a needs assessment with nurse reviewers and a data analysis for federated (standards were locally controlled) data sources. The resulting interface streamlines nurse reviewer workflow by integrating related tasks and data.

  10. Integrated use of computer programs for analysis and optimization of aircraft structures

    Science.gov (United States)

    Moon, Young IN

    1990-01-01

    The objective is to present results from investigating the integrated use of five computer programs: ANALYZE, ASTROS, NASTRAN, OPTSTAT, and VAASEL for analysis and optimization of a given structure. The structure designated for study purposes was the F-15E vertical tail. The concept of integrated use is limited to the capability of using a NASTRAN structural model to run each of the other specified programs. This was actually accomplished in practice by converting a NASTRAN model of the designated structure into an appropriate analysis model. For optimization purposes, the torque-box of the F-15E vertical tail was used.

  11. Integrating forensically and civilly committed adult inpatients in a treatment mall program at a state hospital.

    Science.gov (United States)

    Webster, Steven L; Sheitman, Brian B; Barboriak, Peter N; Harmon, Susan H; Paesler, Betty T; Gordon, Pamela A; Kelly, Shirley Y; Geller, Jeffrey L

    2009-02-01

    This brief report presents outcome data from a 350-bed state psychiatric hospital that integrated its adult forensically and civilly committed inpatient populations within one rehabilitative program. Dorothea Dix Hospital, located in Raleigh, North Carolina, used the "treatment mall" model to offer all of its resources to all adult patients in a centralized setting. Program participation of 100 patients from two long-term civil units was compared with program participation of 94 patients from the hospital's medium- and maximum-security forensic units. The forensic patients were significantly less likely to refuse to join or to leave a group, and they were better engaged in their treatment. The use of restrictive interventions and the incidence of assault were minimal for both groups. The experience at Dorothea Dix Hospital suggests that integrating these populations in rehabilitative programming is not only fiscally responsible but also clinically promising, with no evidence of greater disruptiveness attributable to forensic patients.

  12. Integrative Review of Admission Factors Related to Associate Degree Nursing Program Success.

    Science.gov (United States)

    Olsen, Jeanette M

    2017-02-01

    High attrition in associate degree nursing (ADN) programs contributes to the nursing shortage and causes hardship for students, families, faculty, colleges, and taxpayers. The purpose of this integrative literature review is to identify admission criteria related to ADN program success to inform evidence-based admission policies and reduce attrition. Integrative review methodology, suggested by Whittemore and Knafl, was used. A systematic search of existing professional literature was conducted using five databases and key word searches. The final sample included 26 documents that were analyzed and synthesized with the matrix method. Five categories of admission criteria and factors related to success in ADN programs were revealed from the analysis of findings: academic aptitude, demographic factors, psychological hardiness, specialty skills and experience, and socioeconomic support. ADN programs with a goal of decreasing attrition may want to implement admission selection guidelines that consider applicant criteria and attributes across all five dimensions. [J Nurs Educ. 2017;56(2):85-93.]. Copyright 2017, SLACK Incorporated.

  13. In Situ Remediation Integrated Program, Evaluation and assessment of containment technology

    Energy Technology Data Exchange (ETDEWEB)

    Gerber, M.A.; Fayer, M.J.

    1994-04-01

    The In Situ Remediation Integrated Program (ISRIP) was established by the US Department of Energy (DOE) to advance the state-of-the art of innovative in situ remediation technologies to the point of demonstration and to broaden the applicability of these technologies to the widely varying site remediation requirements throughout the DOE complex. This program complements similar ongoing integrated demonstration programs being conducted at several DOE sites. The ISRIP has been conducting baseline assessments on in situ technologies to support program planning. Pacific Northwest Laboratory conducted an assessment and evaluation of subsurface containment barrier technology in support of ISRIP`s Containment Technology Subprogram. This report summarizes the results of that activity and provides a recommendation for priortizing areas in which additional research and development is needed to advance the technology to the point of demonstration in support of DOE`s site restoration activities.

  14. Low-level feature extraction for edge detection using genetic programming.

    Science.gov (United States)

    Fu, Wenlong; Johnston, Mark; Zhang, Mengjie

    2014-08-01

    Edge detection is a subjective task. Traditionally, a moving window approach is used, but the window size in edge detection is a tradeoff between localization accuracy and noise rejection. An automatic technique for searching a discriminated pixel's neighbors to construct new edge detectors is appealing to satisfy different tasks. In this paper, we propose a genetic programming (GP) system to automatically search pixels (a discriminated pixel and its neighbors) to construct new low-level subjective edge detectors for detecting edges in natural images, and analyze the pixels selected by the GP edge detectors. Automatically searching pixels avoids the problem of blurring edges from a large window and noise influence from a small window. Linear and second-order filters are constructed from the pixels with high occurrences in these GP edge detectors. The experiment results show that the proposed GP system has good performance. A comparison between the filters with the pixels selected by GP and all pixels in a fixed window indicates that the set of pixels selected by GP is compact but sufficiently rich to construct good edge detectors.

  15. A review of the safety features of 6M packagings for DOE programs

    Energy Technology Data Exchange (ETDEWEB)

    1988-12-01

    This report, prepared by a US Department of Energy (DOE) Task Force and organized for clarity into two-page modules, argues that the US Department of Transportation (DOT) Specification-6M packagings (hereafter referred to as 6M packaging, or simply 6M) merit continued DOE use and, if necessary, DOE certification. This report is designed to address the specific requirements of a Safety Analysis Report for Packaging (SARP). While not a SARP, this report constitutes a compilation of all available documentation on 6M packagings. The authors individually, and the Task Force collectively, believe their investigation provides justification for the continued use of 6M packagings because they meet criteria for quality assurance and for safety under normal and accident conditions as defined by the US Nuclear Regulatory Commission (NRC) regulations. This report may be used by DOE managers to assist in deliberations on future requirements for 6M packagings as they are required to support DOE programs. For the purpose of ready evaluation, this report includes categorical topics found in Nuclear Regulatory Guide 7.9, the topical guideline for SARPs. The format, however, will (it is hoped) pleasantly surprise customary reader expectations. For, while maintaining categorical headings and subheadings found in SARPs as a skeleton, the Task Force chose to adopt the document design principles developed by Hughes Aircraft in the 1960s, ''Sequential Thematic Organization of Publications'' (STOP). 37 figs.

  16. NIF Programs Directorate: Integrated Safety Management System Implementation Plan October 2000

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, L

    2001-09-17

    Lawrence Livermore National Laboratory (LLNL) has developed a work structure that serves to ensure work is performed safely and in compliance with applicable environment, safety, and health (ES&H) requirements. Safety begins and ends with the worker ''on the floor'' conducting the work activity. The primary focus of the NIF Programs Integrated Safety Management System (ISMS) is to provide the worker with a sound work environment, necessary resources to perform the job, and adequate procedures and controls to ensure the work is performed safely. It is to this end that the ES&H roles, responsibilities, and authorities are developed and practiced. NIF Programs recognizes and understands the Department of Energy (DOE)/University of California (UC) Contract requirements for ISMS at LLNL and the opportunities and values of the system. NIF Programs understands and supports the DOE Integrated Safety Management (ISM) objective, guiding principles, core functions, and the institutional requirements contained in the LLNL ISMS Description document. NIF Programs is committed to implementing and utilizing ISMS in all of its programs, operations, facilities, and activities and to continuing to assess its successful implementation and use. NIF Programs ISMS has been developed consistent with the requirements of the ''LLNL Integrated Safety Management System Description'' document and specific ISMS implementation needs of NIF Programs. The purpose of this document is to define for NIF Programs' workers and communicate to both senior LLNL management and DOE how and where NIF Programs satisfies the institutional ISM requirements. This document consists of: (1) A NIF Programs document hierarchy that illustrates the flow of ES&H requirements from the directorate level to the worker. (2) A roles, responsibilities, and authorities section for ES&H management chain positions, (3) An ISM implementation matrix that references specific

  17. Rapid Health Care Improvement Science Curriculum Integration Across Programs in a School of Nursing.

    Science.gov (United States)

    Oliver, Brant J; Potter, Mertie; Pomerleau, Mimi; Phillips, Andrew; O'Donnell, Mimi; Cowley, Connie; Sipe, Margie

    This article describes the systematic efforts undertaken by a school of nursing in the Northeastern United States to foster innovation in health professions education. We present an application of modified team coaching and plan-do-study-act improvement methods in an educational context to rapidly integrate a quality and safety curriculum across programs. We discuss applications in generalist, advanced practice, doctoral, residency, and advanced fellowship programs and provide examples of each.

  18. ePortfolio Integration in Teacher Education Programs: Does Context Matter from a Student Perspective?

    OpenAIRE

    Ndoye, Abdou; Parker, Michele A; Albert D. Ritzhaupt

    2012-01-01

    Though ePortfolios have grown in acceptance by teacher education programs across the United States, there still remain many questions regarding whether the tools are meeting student and teacher education program needs. This chapter will address this concern by first describing ePortfolios within teacher education. Next, the chapter will present a stakeholder interaction model and identify the individuals involved in an ePortfolio system. Then, a series of integration questions will be high...

  19. Student and Faculty Perceptions of iPad Integration in a Prelicensure Program.

    Science.gov (United States)

    Rubenstein, Cynthia D; Schubert, Carolyn F

    This article provides an overview of strategies for integration of iPads into a prelicensure nursing program. The study evaluated the actual use of iPads in the classroom, skills and simulation laboratories, and clinical settings and examined the satisfaction of students and faculty with the iPad platform. The study findings provide guidance for a phased-in iPad implementation for prelicensure nursing programs.

  20. Analysis to develop a program for energy-integrated farm systems

    Energy Technology Data Exchange (ETDEWEB)

    Eakin, D.E.; Clark, M.A.; Inaba, L.K.; Johnson, K.I.

    1981-09-01

    A program to use renewable energy resources and possibly develop decentralization of energy systems for agriculture is discussed. The purpose of the research presented is to establish the objective of the program and identify guidelines for program development. The program's objective is determined by: (1) an analysis of the technologies that could be utilized to transform renewable farm resources to energy by the year 2000, (2) the quantity of renewable farm resources that are available, and (3) current energy-use patterns. Individual research, development, and demonstration projects are fit into a national program of energy-integrated farm systems on the basis of: (1) market need, (2) conversion potential, (3) technological opportunities, and (4) acceptability. Quantification of these factors for the purpose of establishing program guidelines is conducted using the following four precepts: (1) market need is identified by current use of energy for agricultural production; (2) conversion potential is determined by the availability of renewable resources; and (3) technological opportunities are determined by the state-of-the-art methods, techniques, and processes that can convert renewable resources into farm energy. Each of these factors is analyzed in Chapters 2 to 4. Chapter 5 draws on the analysis of these factors to establish the objective of the program and identify guidelines for the distribution of program funds. Chapter 6 then discusses the acceptability of integrated farm systems, which can not be quantified like the other factors.

  1. Integrative psychotherapeutic nursing home program to reduce multiple psychiatric symptoms of cognitively impaired patients and caregiver burden: randomized controlled trial

    NARCIS (Netherlands)

    Bakker, T.J.; Duivenvoorden, H.J.; Lee, J. van der; Olde Rikkert, M.G.M.; Beekman, A.T.; Ribbe, M.W.

    2011-01-01

    OBJECTIVE: To test the effectiveness of an integrative psychotherapeutic nursing home program (integrative reactivation and rehabilitation [IRR]) to reduce multiple neuropsychiatry symptoms (MNPS) of cognitively impaired patients and caregiver burden (CB). DESIGN: Randomized controlled trial.

  2. Working together – integration of information literacy in educational programs at Blekinge Institute of Technology

    Directory of Open Access Journals (Sweden)

    Jenny Gunnarsson

    2013-12-01

    • The library can, together with the Schools, create and offer IL modules adapted to the educational programs Today IL education at BTH is quite extensive, but also irregular and highly dependent on contacts with individual teachers, which makes IL education vulnerable. In order to bring this problem to light, and inspired by the Borås model (presented at Creating knowledge VI, as well as Sydostmodellen, the library at BTH contacted the Board of Education during the winter of 2012, and presented a plan on how the library and Schools at BTH could cooperate in order to integrate IL education within all educational programs. Suggestions regarding content, extent, progression, timing, assessment and learning outcomes of the IL education are the focal point of the presented plan. As the first result of the proposal, the library has been commissioned by the BTH Quality Assurance Council to review the situation regarding IL education at BTH together with the educational program directors. In cooperation with the programs, the library should also make a plan for each program on how to integrate IL education as a part of generic skills. At the conference, the following themes were addressed and discussed during our presentation: sustainability of IL education, collaboration within the academy regarding IL education and how integration of IL education at university educational programs is reflected in research on IL in general.

  3. Integrated Data Collection Analysis (IDCA) program--KClO4/Dodecane Mixture

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Shelley, Timothy J. [Air Force Research Lab. (AFRL), Tyndall AFB, FL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2012-05-11

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of a mixture of KClO4 and dodecane—KClO4/dodecane mixture. This material was selected because of the challenge of performing SSST testing of a mixture of solid and liquid materials. The mixture was found to: 1) be less sensitive to impact than RDX, and PETN, 2) less sensitive to friction than RDX and PETN, and 3) less sensitive to spark than RDX and PETN. The thermal analysis showed little or no exothermic features suggesting that the dodecane volatilized at low temperatures. A prominent endothermic feature was observed and assigned to a phase transition of KClO4. This effort, funded by the Department of Homeland Security (DHS), ultimately will put the issues of safe handling of these materials in perspective with standard military explosives. The study is adding SSST testing results for a broad suite of different HMEs to the literature. Ultimately the study has the potential to suggest new guidelines and methods and possibly establish the SSST testing accuracies needed to develop safe handling practices for HMEs. Each participating testing laboratory uses identical test materials and preparation methods wherever possible. Note, however, the test procedures differ among the laboratories. The results are compared among the laboratories and then compared to historical data from various sources. The testing performers involved for the KClO4/dodecane mixture are Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Indian Head Division, Naval Surface Warfare Center, (NSWC IHD), and Air Force Research Laboratory (AFRL/RXQL). These tests are conducted as a proficiency study in order to establish some

  4. Do Plastic Surgery Programs with Integrated Residencies or Subspecialty Fellowships Have Increased Academic Productivity?

    Science.gov (United States)

    Duquette, Stephen P.; Valsangkar, Nakul P.; Sood, Rajiv; Socas, Juan; Zimmers, Teresa A.

    2016-01-01

    Background: The aim of this study was to evaluate the effect of different surgical training pathways on the academic performance of plastic surgical divisions. Methods: Eighty-two academic parameters for 338 plastic surgeons (PS), 1737 general surgeons (GS), and 1689 specialist surgeons (SS) from the top 55 National Institutes of Health (NIH)-funded academic departments of surgery were examined using data gathered from websites, SCOPUS, and NIH Research Portfolio Online Reporting Tools. Results: The median size of a PS division was 7 faculty members. PS faculty had lower median publications (P)/citations (C) (ie, P/C) than GS and SS (PS: 25/328, GS: 35/607, and SS: 40/713, P < 0.05). Publication and citation differences were observed at all ranks: assistant professor (PS: 11/101, GS: 13/169, and SS: 19/249), associate professor (PS: 33/342, GS: 40/691, and SS: 44/780), and professor (PS: 57/968, GS: 97/2451, and SS: 101/2376). PS had a lower percentage of faculty with current/former NIH funding (PS: 13.5%, GS: 22.8%, and SS: 25.1%, P < 0.05). Academic productivity for PS faculty was improved in integrated programs. P/C for PS faculty from divisions with traditional 3-year fellowships was 19/153, integrated 6-year residency was 25/329, and both traditional and 6-year programs were 27/344, P < 0.05. Craniofacial and hand fellowships increased productivity within the integrated residency programs. P/C for programs with a craniofacial fellowship were 32/364 and for those that additionally had a hand fellowship were 45/536. PS faculty at divisions with integrated training programs also had a higher frequency of NIH funding. Conclusions: PS divisions vary in degree of academic productivity. Dramatically improved scholarly output is observed with integrated residency training programs and advanced specialty fellowships. PMID:27014543

  5. Integration of Metabolic Modeling with Gene Co-expression Reveals Transcriptionally Programmed Reactions Explaining Robustness in Mycobacterium tuberculosis

    Science.gov (United States)

    Puniya, Bhanwar Lal; Kulshreshtha, Deepika; Mittal, Inna; Mobeen, Ahmed; Ramachandran, Srinivasan

    2016-01-01

    Robustness of metabolic networks is accomplished by gene regulation, modularity, re-routing of metabolites and plasticity. Here, we probed robustness against perturbations of biochemical reactions of M. tuberculosis in the form of predicting compensatory trends. In order to investigate the transcriptional programming of genes associated with correlated fluxes, we integrated with gene co-expression network. Knock down of the reactions NADH2r and ATPS responsible for producing the hub metabolites, and Central carbon metabolism had the highest proportion of their associated genes under transcriptional co-expression with genes of their flux correlated reactions. Reciprocal gene expression correlations were observed among compensatory routes, fresh activation of alternative routes and in the multi-copy genes of Cysteine synthase and of Phosphate transporter. Knock down of 46 reactions caused the activation of Isocitrate lyase or Malate synthase or both reactions, which are central to the persistent state of M. tuberculosis. A total of 30 new freshly activated routes including Cytochrome c oxidase, Lactate dehydrogenase, and Glycine cleavage system were predicted, which could be responsible for switching into dormant or persistent state. Thus, our integrated approach of exploring transcriptional programming of flux correlated reactions has the potential to unravel features of system architecture conferring robustness. PMID:27000948

  6. Integration of Metabolic Modeling with Gene Co-expression Reveals Transcriptionally Programmed Reactions Explaining Robustness in Mycobacterium tuberculosis.

    Science.gov (United States)

    Puniya, Bhanwar Lal; Kulshreshtha, Deepika; Mittal, Inna; Mobeen, Ahmed; Ramachandran, Srinivasan

    2016-03-22

    Robustness of metabolic networks is accomplished by gene regulation, modularity, re-routing of metabolites and plasticity. Here, we probed robustness against perturbations of biochemical reactions of M. tuberculosis in the form of predicting compensatory trends. In order to investigate the transcriptional programming of genes associated with correlated fluxes, we integrated with gene co-expression network. Knock down of the reactions NADH2r and ATPS responsible for producing the hub metabolites, and Central carbon metabolism had the highest proportion of their associated genes under transcriptional co-expression with genes of their flux correlated reactions. Reciprocal gene expression correlations were observed among compensatory routes, fresh activation of alternative routes and in the multi-copy genes of Cysteine synthase and of Phosphate transporter. Knock down of 46 reactions caused the activation of Isocitrate lyase or Malate synthase or both reactions, which are central to the persistent state of M. tuberculosis. A total of 30 new freshly activated routes including Cytochrome c oxidase, Lactate dehydrogenase, and Glycine cleavage system were predicted, which could be responsible for switching into dormant or persistent state. Thus, our integrated approach of exploring transcriptional programming of flux correlated reactions has the potential to unravel features of system architecture conferring robustness.

  7. Formal verification and testing: An integrated approach to validating Ada programs

    Science.gov (United States)

    Cohen, Norman H.

    1986-01-01

    An integrated set of tools called a validation environment is proposed to support the validation of Ada programs by a combination of methods. A Modular Ada Validation Environment (MAVEN) is described which proposes a context in which formal verification can fit into the industrial development of Ada software.

  8. Integrating Social Responsibility into an Entrepreneurship Education Program: A Case Study

    Science.gov (United States)

    Maistry, Suriamurthee Moonsamy; Ramdhani, Jugathambal

    2010-01-01

    Entrepreneurship education in South Africa is often presented as a neutral discipline. Yet fundamental to any entrepreneurship education program should be the integration of key issues, such as ethics, values and social responsibility. This paper reports on a study that set out to explore student teachers experiences of engaging in an…

  9. 10 CFR 70.62 - Safety program and integrated safety analysis.

    Science.gov (United States)

    2010-01-01

    ... to the technology of the process, and information pertaining to the equipment in the process. (c... have experience in nuclear criticality safety, radiation safety, fire safety, and chemical process... this safety program; namely, process safety information, integrated safety analysis, and management...

  10. Integrating Instructional Technology into a Teacher Education Program: A Three-Tiered Approach

    Science.gov (United States)

    Truesdell, Elizabeth; Birch, Rebecca

    2013-01-01

    This project description examines how a teacher education program integrated new instructional technology through the creation of a Technology Facilitator position in the department. The project proceeded through a three-tiered system of learning "literacy" to establish a knowledge base amongst faculty members, "augmenting"…

  11. Vertical and Horizontal Integration of Laboratory Curricula and Course Projects across the Electronic Engineering Technology Program

    Science.gov (United States)

    Zhan, Wei; Goulart, Ana; Morgan, Joseph A.; Porter, Jay R.

    2011-01-01

    This paper discusses the details of the curricular development effort with a focus on the vertical and horizontal integration of laboratory curricula and course projects within the Electronic Engineering Technology (EET) program at Texas A&M University. Both software and hardware aspects are addressed. A common set of software tools are…

  12. Integrating Science in Applied Psychology Programs: A Student-Operated Journal

    Science.gov (United States)

    Antonius, Daniel; Brown, Adam D.; Todman, McWelling; Safran, Jeremy D.

    2007-01-01

    As a requirement of APA accreditation, many PhD programs in applied psychology subscribe to some variant of the scientist-practitioner model. However, critics have argued that integrating science into an applied psychology curriculum may be too challenging a task. This article describes the development of The New School Psychology Bulletin, a…

  13. Curriculum-Integrated Information Literacy (CIIL) in a Community College Nursing Program: A Practical Model

    Science.gov (United States)

    Argüelles, Carlos

    2016-01-01

    This article describes a strategy to integrate information literacy into the curriculum of a nursing program in a community college. The model is articulated in four explained phases: preparatory, planning, implementation, and evaluation. It describes a collaborative process encouraging librarians to work with nursing faculty, driving students to…

  14. A Integracao de Ensino das Ciencias da Saude (An Integrated Medical Education Program [in Brazil]).

    Science.gov (United States)

    Pourchet-Campos, M. A.; Guimaraes Junior, Paulino

    At the Sixth Annual Reunion of the Brazilian Association of Medical Schools (VI Reuniao Anual da Associacao Brasileira de Escolas Medicas) leaders in the Brazilian medical profession proposed an integrated educational program for training students in the fields of medicine and public health. Under Brazil's present system of education, all…

  15. Preparing Teachers for Technology Integration: Programs, Competencies, and Factors from the Literature

    Science.gov (United States)

    Oliver, Kevin; Townsend, Latricia

    2013-01-01

    This article presents a review of recent literature about preparing teachers for technology integration. The review found six types of training programs are commonly implemented: pre-service training, long-term courses, short-term workshops and institutes, coaching/mentoring, learning communities, and product/assessment approaches. The review…

  16. Integrating Clinical Experiences in a TESOL Teacher Education Program: Curriculum Mapping as Process

    Science.gov (United States)

    Baecher, Laura

    2012-01-01

    Across all certification areas, teacher education is being challenged to better integrate clinical experiences with coursework. This article describes the process of curriculum mapping and its impact on the organization of clinical experiences in a master's TESOL program over a 1-year redesign process. Although curriculum mapping has been employed…

  17. Work-Integrated Learning Process in Tourism Training Programs in Vietnam: Voices of Education and Industry

    Science.gov (United States)

    Khuong, Cam Thi Hong

    2016-01-01

    This paper addresses the work-integrated learning (WIL) initiative embedded in selected tourism training programs in Vietnam. The research was grounded on the framework of stakeholder ethos. Drawing on tourism training curriculum analysis and interviews with lecturers, institutional leaders, industry managers and internship supervisors, this study…

  18. Integration of Digital Dentistry into a Predoctoral Implant Program: Program Description, Rationale, and Utilization Trends.

    Science.gov (United States)

    Afshari, Fatemeh S; Sukotjo, Cortino; Alfaro, Maria F; McCombs, Jeri; Campbell, Stephen D; Knoernschild, Kent L; Yuan, Judy Chia-Chun

    2017-08-01

    A recently revised predoctoral implant curriculum at the University of Illinois at Chicago College of Dentistry integrated digital dentistry into both the preclinical dental implant course and clinical activities. Traditionally, competence in the didactic and clinical parts of predoctoral education in single tooth implant restorations has emphasized the analog impression technique and subsequent mounting of soft tissue working casts. However, computer-aided design/computer-aided manufacturing (CAD/CAM) implant restorations can play a significant role in predoctoral dental education utilizing digital technologies. The goal of the curriculum expansion is to transition from analog to partially digital and, finally, complete digital workflow. The aim of this article is to describe the specific components, implementation, and rationale for the new digitally integrated implant curriculum and present short-term clinical utilization trends.

  19. National strategy for the integration of pharmacovigilance in the Moroccan TB Control Program.

    Science.gov (United States)

    Tanani, Driss Soussi; Serragui, Samira; Hammi, Sanae; Moussa, Latifa Ait; Soulaymani, Abdelmajid; Soulaymani, Rachida; Cherrah, Yahia

    2017-01-01

    The objective of this work is to demonstrate the interest of integration of pharmacovigilance in Moroccan Tuberculosis Control Program (MTCP). The integration of pharmacovigilance in MTCP was conducted in October 2012with the Global Fund support. We compared the reports notified before and after this integration (period 1: January 2010-October2012; period 2: October 2012-December 2013). The detection of signals was based on the Information Component available inVigiMine. We used the SPSS version 10.0 and Med Calc version 7.3 for data analysis. The average number of spontaneous reports increased from 3.6 to 37.4 cases/month (Ppharmacovigilance in Moroccan Tuberculosis Control Program improved the management of ADRs and detected new signals of antituberculosis drugs.

  20. Longitudinal integration of cultural components into a physician assistant program's clinical year may improve cultural competency.

    Science.gov (United States)

    Bahrke, Barbara; De Oliveira, Kathleen; Scheel, Matthew H; Beck, Barbra; Hopp, Jane

    2014-01-01

    This study assessed the efficacy of longitudinal integration of cultural components into the clinical year of a 2-year master of science in physician assistant studies (MSPAS) program. Students submitted cultural reflection papers, gave a medical case/cultural presentation, and participated in cultural awareness discussion groups throughout the clinical year. Students completed the same cultural awareness survey at the conclusion of their clinical year that they had completed at benchmarked intervals during their didactic year. Additionally, cultural competency was assessed during the students' summative objective structured clinical examination (OSCE) using a combination of the program's objectives and established professional standards. Qualitative data suggested that students recognized the importance of cultural competency in providing quality patient care and recognized that remaining culturally competent is an ongoing process. Linear trend analyses revealed significant positive relationships between survey response scores and time in the program. The OSCE's cultural assessment scores indicated cultural competency in broad, general categories, but scores declined as cultural categories narrowed and became more detailed. Continued integration of cultural awareness training and assessment throughout the clinical year of a physician assistant (PA) program may have a positive impact on improving cultural competency. PA programs seeking to improve cultural competency in their students should consider continued integration of cultural components throughout the clinical year.

  1. US Department of Energy Integrated Resource Planning Program: Accomplishments and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    White, D.L. [Oak Ridge National Lab., TN (United States); Mihlmester, P.E. [Aspen Systems Corp., Oak Ridge, TN (United States)

    1993-12-17

    The US Department of Energy Integrated Resource Planning Program supports many activities and projects that enhance the process by which utilities assess demand and supply options and, subsequently, evaluate and select resources. The US Department of Energy program coordinates integrated resource planning in risk and regulatory analysis; utility and regional planning; evaluation and verification; information transfer/technological assistance; and demand-side management. Professional staff from the National Renewable Energy Laboratory, Oak Ridge National Laboratory, Lawrence Berkeley Laboratory, and Pacific Northwest Laboratories collaborate with peers and stakeholders, in particular, the National Association of Regulatory Utility Commissioners, and conduct research and activities for the US Department of Energy. Twelve integrated resource planning activities and projects are summarized in this report. The summaries reflect the diversity of planning and research activities supported by the Department. The summaries also reflect the high levels of collaboration and teaming that are required by the Program and practiced by the researchers. It is concluded that the Program is achieving its objectives by encouraging innovation and improving planning and decision making. Furthermore, as the Department continues to implement planned improvements in the Program, the Department is effectively positioned to attain its ambitious goals.

  2. Integrated neuroscience program: an alternative approach to teaching neurosciences to chiropractic students.

    Science.gov (United States)

    He, Xiaohua; La Rose, James; Zhang, Niu

    2009-01-01

    Most chiropractic colleges do not offer independent neuroscience courses because of an already crowded curriculum. The Palmer College of Chiropractic Florida has developed and implemented an integrated neuroscience program that incorporates neurosciences into different courses. The goals of the program have been to bring neurosciences to students, excite students about the interrelationship of neuroscience and chiropractic, improve students' understanding of neuroscience, and help the students understand the mechanisms underpinning the chiropractic practice. This study provides a descriptive analysis on how the integrated neuroscience program is taught via students' attitudes toward neuroscience and the comparison of students' perceptions of neuroscience content knowledge at different points in the program. A questionnaire consisting of 58 questions regarding the neuroscience courses was conducted among 339 students. The questionnaire was developed by faculty members who were involved in teaching neuroscience and administered in the classroom by faculty members who were not involved in the study. Student perceptions of their neuroscience knowledge, self-confidence, learning strategies, and knowledge application increased considerably through the quarters, especially among the 2nd-year students. The integrated neuroscience program achieved several of its goals, including an increase in students' confidence, positive attitude, ability to learn, and perception of neuroscience content knowledge. The authors believe that such gains can expand student ability to interpret clinical cases and inspire students to become excited about chiropractic research. The survey provides valuable information for teaching faculty to make the course content more relevant to chiropractic students.

  3. Implementation of an integrity management program in a crude oil pipeline system

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, Maria; Tomasella, Marcelo [Oleoductos del Valle, General Roca (Argentina); Rossi, Juan; Pellicano, Adolfo [SINTEC S.A. , Mar del Plata, Buenos Aires (Argentina)

    2005-07-01

    The implementation of an Integrity Management Program (IMP) in a crude oil pipeline system is focused on the accomplishment of two primary corporative objectives: to increase safety operation margins and to optimize available resources. A proactive work philosophy ensures the safe and reliable operation of the pipeline in accordance with current legislation. The Integrity Management Program is accomplished by means of an interdisciplinary team that defines the strategic objectives that complement and are compatible with the corporative strategic business plan. The implementation of the program is based on the analysis of the risks due to external corrosion, third party damage, design and operations, and the definition of appropriate mitigation, inspection and monitoring actions, which will ensure long-term integrity of the assets. By means of a statistical propagation model of the external defects, reported by high-resolution magnetic inspection tool (MFL), together with the information provided by corrosion sensors, field repair interventions, close internal surveys and operation data, projected defect depth; remaining strength and failure probability distributions were obtained. From the analysis, feasible courses of action were established, including the inspection and repair plan, the internal inspection program and both corrosion monitoring and mitigation programs. (author)

  4. Association between U.S. state AIDS Drug Assistance Program (ADAP features and HIV antiretroviral therapy initiation, 2001-2009.

    Directory of Open Access Journals (Sweden)

    David B Hanna

    Full Text Available U.S. state AIDS Drug Assistance Programs (ADAPs are federally funded to provide antiretroviral therapy (ART as the payer of last resort to eligible persons with HIV infection. States differ regarding their financial contributions to and ways of implementing these programs, and it remains unclear how this interstate variability affects HIV treatment outcomes.We analyzed data from HIV-infected individuals who were clinically-eligible for ART between 2001 and 2009 (i.e., a first reported CD4+ <350 cells/uL or AIDS-defining illness from 14 U.S. cohorts of the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD. Using propensity score matching and Cox regression, we assessed ART initiation (within 6 months following eligibility and virologic suppression (within 1 year based on differences in two state ADAP features: the amount of state funding in annual ADAP budgets and the implementation of waiting lists. We performed an a priori subgroup analysis in persons with a history of injection drug use (IDU.Among 8,874 persons, 56% initiated ART within six months following eligibility. Persons living in states with no additional state contribution to the ADAP budget initiated ART on a less timely basis (hazard ratio [HR] 0.73, 95% CI 0.60-0.88. Living in a state with an ADAP waiting list was not associated with less timely initiation (HR 1.12, 95% CI 0.87-1.45. Neither additional state contributions nor waiting lists were significantly associated with virologic suppression. Persons with an IDU history initiated ART on a less timely basis (HR 0.67, 95% CI 0.47-0.95.We found that living in states that did not contribute additionally to the ADAP budget was associated with delayed ART initiation when treatment was clinically indicated. Given the changing healthcare environment, continued assessment of the role of ADAPs and their features that facilitate prompt treatment is needed.

  5. Planning integration FY 1995 Multi-Year Program Plan (MYPP)/Fiscal Year Work Plan (FYWP)

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    This Multi-Year Program Plan (MYPP) for the Planning Integration Program, Work Breakdown structure (WBS) Element 1.8.2, is the primary management tool to document the technical, schedule, and cost baseline for work directed by the US Department of Energy (DOE), Richland Operations Office (RL). As an approved document, it establishes a binding agreement between RL and the performing contractors for the work to be performed. It was prepared by the Westinghouse Hanford Company (WHC) and the Pacific Northwest Laboratory (PNL). This MYPP provides a picture from fiscal year 1995 through FY 2001 for the Planning Integration Program. The MYPP provides a window of detailed information for the first three years. It also provides `execution year` work plans. The MYPP provides summary information for the next four years, documenting the same period as the Activity Data Sheets.

  6. The effects of the integration of external and internal communication features in digital magazines on consumers' magazine attitude

    NARCIS (Netherlands)

    Rauwers, F.; Voorveld, H.A.M.; Neijens, P.C.

    2016-01-01

    This study investigates the effects of external and internal communication features on consumers' digital magazine attitude, and the processes (i.e., perceived interactivity and social presence) underlying these effects. Both feature types enable communication between two or more people. Though, in

  7. Developing the Adversity Quotient of Mathayomsuksa 3 Students using the Integrated Group Counseling Program

    Directory of Open Access Journals (Sweden)

    Pantheetra Samart

    2017-11-01

    Full Text Available The purposes of this study were (1 to study the definitions, and components of the adversity quotient ; (2 to develop the integrated group counseling program ; and, (3 to compare the results of using the integrated group counseling program to develop the adversity quotient of students. The samples of study consisted of 16 students who enrolled in Mathayomsuksa 3 in an academic year 2015 at Mahasarakham University Demonstration School (secondary. They were randomly selected and divided into two groups: an experimental group and a control group, each of which contained 8 students. The instruments were the 5 rating scale adversity quotient test, integrated group counseling program, behavioral observation and recording form. The data were analyzed by using the Friedman Test, the Wilcoxon Match Pair Signed – Ranks Test and the Mann - Whitney U – Test, respectively. The results of this study indicated that the adversity quotient was defined as the expression of the students on understanding, embracing and responsibility to the adversity, planning and controlling to deal the adversity with patience, perseverance and overcoming the adversity There were four components of the adversity quotient, that is, controlling, responsibility, adversity accessing and analyzing, and motivation and patience. These components were put in the integrated group counseling program to develop the adversity quotient of students. This program was validated by the experts with known appropriate values of 4.00 to 4.80 and standard deviation values of 0.00 to 0.89. After this program was implemented, it was found that the mean scores of the adversity quotient in the experimental group after participating in the program were higher than those before participating in the program at the statistically significance level of .05. When considering the retention behaviors, it was found that the mean scores of the adversity quotient in the experimental group during the follow-up 1

  8. Analisis Efektivitas Perangkat pada Program Desa Broadband Terpadu [Analysis of Device Effectiveness in Integrated Broadband Village Program

    Directory of Open Access Journals (Sweden)

    Hilarion Hamjen

    2016-12-01

    Full Text Available Pemerintah berkomitmen mendukung pertumbuhan e-commerce dan ekonomi digital di Indonesia untuk mencapai visi Indonesia 2020 sebagai negara ekonomi digital terbesar di Asia Tenggara. Secara fundamental diperlukan dukungan konektivitas nasional dari tingkat pusat sampai ke tingkat lokal, salah satunya melalui program KPU/USO yaitu program DBT (Desa Broadband Terpadu. Penelitian ini bertujuan untuk mengetahui efektivitas perangkat pada program DBT phase 1 dan keterkaitannya dengan konektivitas, dengan menggunakan metode analisis kepentingan kinerja dan uji statistik Chi square. Berdasarkan hasil penelitian diketahui bahwa efektivitas perangkat meliputi variabel kondisi, fungsi, pemeliharaan dan pemanfaatan rata-rata adalah 84,5 persen. Dengan nilai efektivitas tersebut diketahui bahwa keseluruhan variabel kondisi perangkat, fungsi dan pemanfaatannya tidak mempengaruhi konektivitas.  *****The Indonesian government has a strong commitment in supporting the growth of e-commerce and Digital Economy in Indonesia to attain Indonesia’s vision by 2020 as the largest digital economy nation in Southeast Asia. Fundamentally, the national connectivity supports from central level to local level are needed, where one of them comes from Integrated Broadband Village program. This research determines the effectiveness of devices in the DBT program and its correlation to the connectivity, by using importance-performance analysis method and Chi-square statistical test. It is known from the result that the effectiveness of devices, including condition, function, maintenance, and utilization variables, achieves 84.5 percent on average. The value shows that all mentioned variables have insignificant correlations to the connectivity.

  9. A Program to Protect Integrity of Body-Mind-Spirit: Mindfulness Based Stress Reduction Program

    Directory of Open Access Journals (Sweden)

    Oznur Korukcu

    2015-03-01

    Full Text Available Mindfulness-based applications allow health care staffs to understand themselves as well as other individuals. Awareness based applications are not only stress reduction techniques but also a way of understanding the life and human existence, and it should not be only used to cope with the diseases. Emotions, thoughts and judgments of people might give direction to their life sometimes. Accessing a life without judgment and negative feelings brings a peaceful and happy life together. Mindfulness based stress reduction exercises may help to enjoy the present time, to cope with the challenges, stress and diseases and accept the negative life experiences rather than to question their reasons. About three decades ago, Kabat-Zin conducted the first investigation of Mindfulness-Based Stress Reduction program which is used commonly all around the world. The 8-weeks program, which contains mindful living exercises (such as eating, walking, cooking, etc., yoga, body scan and meditation practices, requires doing daily life activity and meditation with attention, openness and acceptance. The aim of this review article is to give information about Mindfulness Based Stress Reduction program and to emphasize its importance. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2015; 7(1: 68-80

  10. Integrating Buprenorphine Into an Opioid Treatment Program: Tailoring Care for Patients With Opioid Use Disorders

    Science.gov (United States)

    Polydorou, Soteri; Ross, Stephen; Coleman, Peter; Duncan, Laura; Roxas, Nichole; Thomas, Anil; Mendoza, Sonia; Hansen, Helena

    2016-01-01

    Objectives This report identifies the institutional barriers to, and benefits of, buprenorphine maintenance treatment (BMT) integration in an established hospital-based opioid treatment program (OTP). Methods This case study presents the authors’ experiences at the clinic, hospital, and corporation levels during efforts to integrate BMT into a hospital-based OTP in New York City and a descriptive quantitative analysis of the characteristics of hospital outpatients treated with buprenorphine from 2006 to 2013 (N=735). Results Integration of BMT into an OTP offered patients the flexibility to transition between intensive structured care and primary care or outpatient psychiatry according to need. Main barriers encountered were regulations, clinical logistics of dispensing medications, internal cost and reimbursement issues, and professional and cultural resistance. Conclusions Buprenorphine integration offers a model for other OTPs to facilitate partnerships among primary care and mental health clinics to better serve diverse patients with varying clinical needs and with varying levels of social support. PMID:27745534

  11. A Large-Scale Design Integration Approach Developed in Conjunction with the Ares Launch Vehicle Program

    Science.gov (United States)

    Redmon, John W.; Shirley, Michael C.; Kinard, Paul S.

    2012-01-01

    This paper presents a method for performing large-scale design integration, taking a classical 2D drawing envelope and interface approach and applying it to modern three dimensional computer aided design (3D CAD) systems. Today, the paradigm often used when performing design integration with 3D models involves a digital mockup of an overall vehicle, in the form of a massive, fully detailed, CAD assembly; therefore, adding unnecessary burden and overhead to design and product data management processes. While fully detailed data may yield a broad depth of design detail, pertinent integration features are often obscured under the excessive amounts of information, making them difficult to discern. In contrast, the envelope and interface method results in a reduction in both the amount and complexity of information necessary for design integration while yielding significant savings in time and effort when applied to today's complex design integration projects. This approach, combining classical and modern methods, proved advantageous during the complex design integration activities of the Ares I vehicle. Downstream processes, benefiting from this approach by reducing development and design cycle time, include: Creation of analysis models for the Aerodynamic discipline; Vehicle to ground interface development; Documentation development for the vehicle assembly.

  12. Human Research Program Integrated Research Plan: December 20, 2007, Interim Baseline

    Science.gov (United States)

    2008-01-01

    The Human Research Program (HRP) delivers human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration. This Integrated Research Plan (IRP) describes the program s research activities that are intended to address the needs of human space exploration and serve HRP customers. The timescale of human space exploration is envisioned to take many decades. The IRP illustrates the program s research plan through the timescale of early lunar missions of extended duration. The document serves several purposes for the Human Research Program: The IRP provides a means to assure that the most significant risks to human space explorers are being adequately mitigated and/or addressed, The IRP shows the relationship of research activities to expected outcomes and need dates, The IRP shows the interrelationships among research activities that may interact to produce products that are integrative or cross defined research disciplines, The IRP illustrates the non-deterministic nature of research and technology activities by showing expected decision points and potential follow-on activities, The IRP shows the assignments of responsibility within the program organization and, as practical, the intended solicitation approach, The IRP shows the intended use of research platforms such as the International Space Station, NASA Space Radiation Laboratory, and various space flight analogs. The IRP does not show all budgeted activities of the Human research program, as some of these are enabling functions, such as management, facilities and infrastructure

  13. Integrated musculoskeletal rehabilitation care at a comprehensive combat and complex casualty care program.

    Science.gov (United States)

    Goldberg, Capt Kathy F; Green, Bart; Moore, Jacqueline; Wyatt, Marilynn; Boulanger, Lynn; Belnap, Brian; Harsch, Peter; Donaldson, David S

    2009-01-01

    The purpose of this study is to describe the musculoskeletal rehabilitation model used to care for combat and severely wounded or ill US military service members at an integrated Comprehensive Combat and Complex Casualty Care center located at Naval Medical Center San Diego. Through a collaborative and iterative process, providers from the various services included at the Comprehensive Combat and Complex Casualty Care program developed a description of the integration of services provided at this location. After construction of the facility in 2007, the program has provided services for approximately 2 years. Eighteen different health care providers from 10 different specialties provide integrated musculoskeletal services, which include primary care, physical therapy, occupational therapy, vestibular therapy, gait analysis, prosthetics, recreational therapy, and chiropractic care. At the time of this writing (early 2009), the program had provided musculoskeletal rehabilitation care to approximately 500 patients, 58 with amputations, from the operational theater, Veterans Affairs, other military treatment facilities, and local trauma centers. The complex nature of combat wounded and polytrauma patients requires an integrated and interdisciplinary team that is innovative, adaptable, and focused on the needs of the patient. This article presents a description of the model and the experiences of our musculoskeletal rehabilitation team; it is our hope that this article will assist other centers and add to the small but emerging literature on this topic.

  14. DOE`s integrated low-level waste management program and strategic planning

    Energy Technology Data Exchange (ETDEWEB)

    Duggan, G. [Dept. of Energy, Washington, DC (United States). Office of Environmental Restoration and Waste Management; Hwang, J. [Science Applications International Corp., Germantown, MD (United States)

    1993-03-01

    To meet the DOE`s commitment to operate its facilities in a safe, economic, and environmentally sound manner, and to comply with all applicable federal, state, and local rules, regulations, and agreements, DOE created the Office of Environmental Restoration and Waste Management (EM) in 1989 to focus efforts on controlling waste management and cleaning up contaminated sites. In the first few years of its existence, the Office of Waste Management (EM-30) has concentrated on operational and corrective activities at the sites. In 1992, the Office of Waste Management began to apply an integrated approach to managing its various waste types. Consequently, DOE established the Low-Level Waste Management Program (LLWMP) to properly manage its complex-wide LLW in a consistent manner. The objective of the LLWMP is to build and operate an integrated, safe, and cost-effective program to meet the needs of waste generators. The program will be based on acceptable risk and sound planning, resulting in public confidence and support. Strategic planning of the program is under way and is expected to take two to three years before implementation of the integrated waste management approach.

  15. Educating Social Workers for Practice in Integrated Health Care: A Model Implemented in a Graduate Social Work Program

    Science.gov (United States)

    Mattison, Debra; Weaver, Addie; Zebrack, Brad; Fischer, Dan; Dubin, Leslie

    2017-01-01

    This article introduces a curricular innovation, the Integrated Health Scholars Program (IHSP), developed to prepare master's-level social work students for practice in integrated health care settings, and presents preliminary findings related to students' self-reported program competencies and perceptions. IHSP, implemented in a…

  16. A review of integrity TM

    NARCIS (Netherlands)

    Veldkamp, Bernard P.

    2008-01-01

    Integrity™, an online application for testing both the statistical integrity of the test and the academic integrity of the examinees, was evaluated for this review. Program features and the program output are described. An overview of the statistics in Integrity™ is provided, and the application is

  17. An Integrated Constraint Programming Approach to Scheduling Sports Leagues with Divisional and Round-robin Tournaments

    Energy Technology Data Exchange (ETDEWEB)

    Carlsson, Mats; Johansson, Mikael; Larson, Jeffrey

    2014-01-01

    Previous approaches for scheduling a league with round-robin and divisional tournaments involved decomposing the problem into easier subproblems. This approach, used to schedule the top Swedish handball league Elitserien, reduces the problem complexity but can result in suboptimal schedules. This paper presents an integrated constraint programming model that allows to perform the scheduling in a single step. Particular attention is given to identifying implied and symmetry-breaking constraints that reduce the computational complexity significantly. The experimental evaluation of the integrated approach takes considerably less computational effort than the previous approach.

  18. Progress and status of the Integral Fast Reactor (IFR) development program

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Yoon I.

    1992-01-01

    In the Integral Fast Reactor (IFR) development program, the entire reactor system -- reactor, fuel cycle, and waste process is being developed and optimized at the same time as a single integral entity. The ALMR reactor plant design is being developed by an industrial team headed by General Electric and is presented in a companion paper. Detailed discussions on the present status of the IFR technology development activities in the areas of fuels, pyroprocessing, safety, core design, and fuel cycle demonstration are presented in the other two companion papers that follows this.

  19. Progress and status of the Integral Fast Reactor (IFR) development program

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Yoon I.

    1992-04-01

    In the Integral Fast Reactor (IFR) development program, the entire reactor system -- reactor, fuel cycle, and waste process is being developed and optimized at the same time as a single integral entity. The ALMR reactor plant design is being developed by an industrial team headed by General Electric and is presented in a companion paper. Detailed discussions on the present status of the IFR technology development activities in the areas of fuels, pyroprocessing, safety, core design, and fuel cycle demonstration are presented in the other two companion papers that follows this.

  20. Integrated Data Collection Analysis (IDCA) Program — IDCA Quarterly Program Review, September 14 and 15, 2010

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (IHD-NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (IHD-NSWC), Indian Head, MD (United States). Indian Head Division; Shelley, Timothy J. [Air Force Research Lab. (AFRL/RXQF), Tyndall AFB, FL (United States); Reyes, Jose A. [Applied Research Associates, Inc., Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2012-02-07

    The IDCA conducted a program review at Los Alamos National Laboratory, September 14 and 15, 2010. The review was divided into three parts: 1) an update on the current status of the program, 2) an information exchange and discussion on technical details for current issues and future planning, and 3) a tour of the SSST testing facilities at LANL. The meeting started with an update from DHS by Laura Parker and a restating of some of the objectives of the Proficiency Test of which the IDCA is currently engaged. This update was followed by a discussion of some high level programmatic issues particularly about ways of communicating the overall goals of the IDCA to non-technical representatives. The final topic focused on the difficulty of releasing information, including the DHS approval process, ITAR, and open publication. Next JGR presented a technical summary of accomplishments, schedule, milestones, and future directions. These key points made were: 1) about 1/3 of the materials have been tested, 2) some participants are behind others causing a lag in report writing, 3) method reports have been assigned to various participants to speed up the process of reporting, 4) the SSST Compendium needs reformatting and restructuring, and 5) the Compendium needs a web site to house with access control. After the technical update, some of the Proficiency Test results were shown comparing data from the various laboratories. These results included comparisons of the RDX standard, KC/sugar mixtures (-100 mesh and as received), KC/dodecane, KP/Al, and KP/C. Impact, friction, ESD, and DSC results were the focus. All the participants were involved in these discussions. This report includes summary notes, presentations, and explanatory information.

  1. 34 CFR 425.1 - What is the Demonstration Projects for the Integration of Vocational and Academic Learning Program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the Demonstration Projects for the Integration... EDUCATION DEMONSTRATION PROJECTS FOR THE INTEGRATION OF VOCATIONAL AND ACADEMIC LEARNING PROGRAM General § 425.1 What is the Demonstration Projects for the Integration of Vocational and Academic Learning...

  2. 49 CFR 192.915 - What knowledge and training must personnel have to carry out an integrity management program?

    Science.gov (United States)

    2010-10-01

    ...: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.915 What knowledge... to the integrity management program possesses and maintains a thorough knowledge of the integrity... 49 Transportation 3 2010-10-01 2010-10-01 false What knowledge and training must personnel have to...

  3. CLASSIFICATION OF URBAN FEATURE FROM UNMANNED AERIAL VEHICLE IMAGES USING GASVM INTEGRATION AND MULTI-SCALE SEGMENTATION

    Directory of Open Access Journals (Sweden)

    M. Modiri

    2015-12-01

    Full Text Available The use of UAV in the application of photogrammetry to obtain cover images and achieve the main objectives of the photogrammetric mapping has been a boom in the region. The images taken from REGGIOLO region in the province of, Italy Reggio -Emilia by UAV with non-metric camera Canon Ixus and with an average height of 139.42 meters were used to classify urban feature. Using the software provided SURE and cover images of the study area, to produce dense point cloud, DSM and Artvqvtv spatial resolution of 10 cm was prepared. DTM area using Adaptive TIN filtering algorithm was developed. NDSM area was prepared with using the difference between DSM and DTM and a separate features in the image stack. In order to extract features, using simultaneous occurrence matrix features mean, variance, homogeneity, contrast, dissimilarity, entropy, second moment, and correlation for each of the RGB band image was used Orthophoto area. Classes used to classify urban problems, including buildings, trees and tall vegetation, grass and vegetation short, paved road and is impervious surfaces. Class consists of impervious surfaces such as pavement conditions, the cement, the car, the roof is stored. In order to pixel-based classification and selection of optimal features of classification was GASVM pixel basis. In order to achieve the classification results with higher accuracy and spectral composition informations, texture, and shape conceptual image featureOrthophoto area was fencing. The segmentation of multi-scale segmentation method was used.it belonged class. Search results using the proposed classification of urban feature, suggests the suitability of this method of classification complications UAV is a city using images. The overall accuracy and kappa coefficient method proposed in this study, respectively, 47/93% and 84/91% was.

  4. Mixed Waste Integrated Program: A technology assessment for mercury-containing mixed wastes

    Energy Technology Data Exchange (ETDEWEB)

    Perona, J.J.; Brown, C.H.

    1993-03-01

    The treatment of mixed wastes must meet US Environmental Protection Agency (EPA) standards for chemically hazardous species and also must provide adequate control of the radioactive species. The US Department of Energy (DOE) Office of Technology Development established the Mixed Waste Integrated Program (MWIP) to develop mixed-waste treatment technology in support of the Mixed Low-Level Waste Program. Many DOE mixed-waste streams contain mercury. This report is an assessment of current state-of-the-art technologies for mercury separations from solids, liquids, and gases. A total of 19 technologies were assessed. This project is funded through the Chemical-Physical Technology Support Group of the MWIP.

  5. Integrating the Jewish Dietary Laws into a dietetics program. Kashruth in a dietetics curriculum.

    Science.gov (United States)

    Natow, A B; Heslin, J A; Raven, B C

    1975-07-01

    A clinical and community dietetics program integrates Kashruth, the Jewish Dietary Laws, into its curriculum. Simply defined, kosher means fit for consumption. Emblems used throughout the United States and Canada to indicate a program of rabbinic endoresment and supervision of canned, boxed, and bottled products are included. An existing kosher unit is described, and guidelines for establishing a kosher food science laboratory unit are offered. Suggestions for instituting kosher foodservice in health care facilities are given. Therapeutic applications of Kashruth are suggested, and approved therapeutic food products are listed.

  6. Annual Report of the Integrated Status and Effectiveness Monitoring Program: Fiscal Year 2008

    Energy Technology Data Exchange (ETDEWEB)

    Terraqua, Inc. (Wauconda, WA)

    2009-07-20

    This document was created as an annual report detailing the accomplishments of the Integrated Status and Effectiveness Monitoring Program (ISEMP) in the Upper Columbia Basin in fiscal year 2008. The report consists of sub-chapters that reflect the various components of the program. Chapter 1 presents a report on programmatic coordination and accomplishments, and Chapters 2 through 4 provide a review of how ISEMP has progressed during the 2008 fiscal year in each of the pilot project subbasins: the John Day (Chapter 2), Wenatchee/Entiat (Chapter 3) and Salmon River (Chapter 4). Chapter 5 presents a report on the data management accomplishments in 2008.

  7. New flexible origination technology based on electron-beam lithography and its integration into security devices in combination with covert features based on DNA authentication

    Science.gov (United States)

    Drinkwater, John K.; Ryzi, Zbynek; Outwater, Chris S.

    2002-04-01

    Embossed diffractive optically variable devices are becoming increasingly familiar security items on plastic cards, banknotes, security documents and on branded goods and media to protect against counterfeit, protect copyright and to evidence tamper. Equally as this devices become both more widely available there is a pressing requirement for security technology upgrades to keep ahead of technology advances available to potential counterfeiters. This paper describes a new generation electron beam DOVID origination technology particularly suitable for high security applications. Covert marking of security devices is provided using the DNA matrix by creating and verifying unique DNA sequences. This integration of this into practical security features in combination with covert features based on DNA matrix authentication and other more straightforwardly authenticable features to provide multi- technology security solutions will be described.

  8. Association between U.S. State AIDS Drug Assistance Program (ADAP) Features and HIV Antiretroviral Therapy Initiation, 2001–2009

    Science.gov (United States)

    Hanna, David B.; Buchacz, Kate; Gebo, Kelly A.; Hessol, Nancy A.; Horberg, Michael A.; Jacobson, Lisa P.; Kirk, Gregory D.; Kitahata, Mari M.; Korthuis, P. Todd; Moore, Richard D.; Napravnik, Sonia; Patel, Pragna; Silverberg, Michael J.; Sterling, Timothy R.; Willig, James H.; Collier, Ann; Samji, Hasina; Thorne, Jennifer E.; Althoff, Keri N.; Martin, Jeffrey N.; Rodriguez, Benigno; Stuart, Elizabeth A.; Gange, Stephen J.

    2013-01-01

    Background U.S. state AIDS Drug Assistance Programs (ADAPs) are federally funded to provide antiretroviral therapy (ART) as the payer of last resort to eligible persons with HIV infection. States differ regarding their financial contributions to and ways of implementing these programs, and it remains unclear how this interstate variability affects HIV treatment outcomes. Methods We analyzed data from HIV-infected individuals who were clinically-eligible for ART between 2001 and 2009 (i.e., a first reported CD4+ <350 cells/uL or AIDS-defining illness) from 14 U.S. cohorts of the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). Using propensity score matching and Cox regression, we assessed ART initiation (within 6 months following eligibility) and virologic suppression (within 1 year) based on differences in two state ADAP features: the amount of state funding in annual ADAP budgets and the implementation of waiting lists. We performed an a priori subgroup analysis in persons with a history of injection drug use (IDU). Results Among 8,874 persons, 56% initiated ART within six months following eligibility. Persons living in states with no additional state contribution to the ADAP budget initiated ART on a less timely basis (hazard ratio [HR] 0.73, 95% CI 0.60–0.88). Living in a state with an ADAP waiting list was not associated with less timely initiation (HR 1.12, 95% CI 0.87–1.45). Neither additional state contributions nor waiting lists were significantly associated with virologic suppression. Persons with an IDU history initiated ART on a less timely basis (HR 0.67, 95% CI 0.47–0.95). Conclusions We found that living in states that did not contribute additionally to the ADAP budget was associated with delayed ART initiation when treatment was clinically indicated. Given the changing healthcare environment, continued assessment of the role of ADAPs and their features that facilitate prompt treatment is needed. PMID:24260137

  9. Space station integrated propulsion and fluid systems study. Space station program fluid management systems databook

    Science.gov (United States)

    Bicknell, B.; Wilson, S.; Dennis, M.; Lydon, M.

    1988-01-01

    Commonality and integration of propulsion and fluid systems associated with the Space Station elements are being evaluated. The Space Station elements consist of the core station, which includes habitation and laboratory modules, nodes, airlocks, and trusswork; and associated vehicles, platforms, experiments, and payloads. The program is being performed as two discrete tasks. Task 1 investigated the components of the Space Station architecture to determine the feasibility and practicality of commonality and integration among the various propulsion elements. This task was completed. Task 2 is examining integration and commonality among fluid systems which were identified by the Phase B Space Station contractors as being part of the initial operating capability (IOC) and growth Space Station architectures. Requirements and descriptions for reference fluid systems were compiled from Space Station documentation and other sources. The fluid systems being examined are: an experiment gas supply system, an oxygen/hydrogen supply system, an integrated water system, the integrated nitrogen system, and the integrated waste fluids system. Definitions and descriptions of alternate systems were developed, along with analyses and discussions of their benefits and detriments. This databook includes fluid systems descriptions, requirements, schematic diagrams, component lists, and discussions of the fluid systems. In addition, cost comparison are used in some cases to determine the optimum system for a specific task.

  10. Narrowing the Retention Gap of High School Females in an Integrated STEM Program

    Science.gov (United States)

    Seigworth, Clifton F.

    This study examined the differences in the overall sense of belonging of female high school students in an integrated STEM program in comparison to gender, ethnicity, and socio-economic status. The researcher surveyed female and male students in grades 8 through 12 to determine if there were differences in attitudes toward STEM. Additionally, the researcher assessed the STEM teachers to determine if a relationship existed between the teachers' years of experience and level of education to their self-efficacy and attitudes pertaining to STEM. Lastly, the administrators and counselors of both the middle and high schools were surveyed using a written evaluation to understand and gain their perspective of an integrated STEM program with regard to increasing female participation in STEM-related courses.

  11. Constellation Program Human-System Integration Requirements. Revision E, Nov. 19, 2010

    Science.gov (United States)

    Dory, Jonathan

    2010-01-01

    The Human-Systems Integration Requirements (HSIR) in this document drive the design of space vehicles, their systems, and equipment with which humans interface in the Constellation Program (CxP). These requirements ensure that the design of Constellation (Cx) systems is centered on the needs, capabilities, and limitations of the human. The HSIR provides requirements to ensure proper integration of human-to-system interfaces. These requirements apply to all mission phases, including pre-launch, ascent, Earth orbit, trans-lunar flight, lunar orbit, lunar landing, lunar ascent, Earth return, Earth entry, Earth landing, post-landing, and recovery. The Constellation Program must meet NASA's Agency-level human rating requirements, which are intended to ensure crew survival without permanent disability. The HSIR provides a key mechanism for achieving human rating of Constellation systems.

  12. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.

    Science.gov (United States)

    Arts, Rob J W; Novakovic, Boris; Ter Horst, Rob; Carvalho, Agostinho; Bekkering, Siroon; Lachmandas, Ekta; Rodrigues, Fernando; Silvestre, Ricardo; Cheng, Shih-Chin; Wang, Shuang-Yin; Habibi, Ehsan; Gonçalves, Luís G; Mesquita, Inês; Cunha, Cristina; van Laarhoven, Arjan; van de Veerdonk, Frank L; Williams, David L; van der Meer, Jos W M; Logie, Colin; O'Neill, Luke A; Dinarello, Charles A; Riksen, Niels P; van Crevel, Reinout; Clish, Clary; Notebaart, Richard A; Joosten, Leo A B; Stunnenberg, Hendrik G; Xavier, Ramnik J; Netea, Mihai G

    2016-12-13

    Induction of trained immunity (innate immune memory) is mediated by activation of immune and metabolic pathways that result in epigenetic rewiring of cellular functional programs. Through network-level integration of transcriptomics and metabolomics data, we identify glycolysis, glutaminolysis, and the cholesterol synthesis pathway as indispensable for the induction of trained immunity by β-glucan in monocytes. Accumulation of fumarate, due to glutamine replenishment of the TCA cycle, integrates immune and metabolic circuits to induce monocyte epigenetic reprogramming by inhibiting KDM5 histone demethylases. Furthermore, fumarate itself induced an epigenetic program similar to β-glucan-induced trained immunity. In line with this, inhibition of glutaminolysis and cholesterol synthesis in mice reduced the induction of trained immunity by β-glucan. Identification of the metabolic pathways leading to induction of trained immunity contributes to our understanding of innate immune memory and opens new therapeutic avenues. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Integration of simulation in postgraduate studies in Saudi Arabia: The current practice in anesthesia training program

    Science.gov (United States)

    Arab, Abeer; Alatassi, Abdulaleem; Alattas, Elias; Alzoraigi, Usamah; AlZaher, Zaki; Ahmad, Abdulaziz; Albabtain, Hesham; Boker, Abdulaziz

    2017-01-01

    The educational programs in the Saudi Commission for Health Specialties are developing rapidly in the fields of technical development. Such development is witnessed, particularly in the scientific areas related to what is commonly known as evidence-based medicine. This review highlights the critical need and importance of integrating simulation into anesthesia training and assessment. Furthermore, it describes the current utilization of simulation in anesthesia and critical care assessment process. PMID:28442961

  14. Evaluation Of Model Based Systems Engineering Processes For Integration Into Rapid Acquisition Programs

    Science.gov (United States)

    2016-09-01

    integration of new capabilities seamlessly into an existing software baseline or architecture  the ability to effectively assess performance at... software development,” (b) “model driven development,” (c) “ architecture centric development,” (d) “specification-driven development,” and (e) “generative...Development Process Like the MK54 program, this Radar project utilized an agile Vee process, in a Scrum environment. However, in this case, the software

  15. Single session of integrated "Silver Yoga" program improves cardiovascular parameters in senior citizens

    Directory of Open Access Journals (Sweden)

    Ananda Balayogi Bhavanani

    2015-06-01

    Conclusion: There is a healthy reduction in HR, BP and derived cardiovascular indices following a single yoga session in geriatric subjects. These changes may be attributed to enhanced harmony of cardiac autonomic function as a result of coordinated breath-body work and mind-body relaxation due to an integrated and #8220;Silver Yoga and #8221; program. [J Intercult Ethnopharmacol 2015; 4(2.000: 134-137

  16. MethBank: a database integrating next-generation sequencing single-base-resolution DNA methylation programming data.

    Science.gov (United States)

    Zou, Dong; Sun, Shixiang; Li, Rujiao; Liu, Jiang; Zhang, Jing; Zhang, Zhang

    2015-01-01

    DNA methylation plays crucial roles during embryonic development. Here we present MethBank (http://dnamethylome.org), a DNA methylome programming database that integrates the genome-wide single-base nucleotide methylomes of gametes and early embryos in different model organisms. Unlike extant relevant databases, MethBank incorporates the whole-genome single-base-resolution methylomes of gametes and early embryos at multiple different developmental stages in zebrafish and mouse. MethBank allows users to retrieve methylation levels, differentially methylated regions, CpG islands, gene expression profiles and genetic polymorphisms for a specific gene or genomic region. Moreover, it offers a methylome browser that is capable of visualizing high-resolution DNA methylation profiles as well as other related data in an interactive manner and thus is of great helpfulness for users to investigate methylation patterns and changes of gametes and early embryos at different developmental stages. Ongoing efforts are focused on incorporation of methylomes and related data from other organisms. Together, MethBank features integration and visualization of high-resolution DNA methylation data as well as other related data, enabling identification of potential DNA methylation signatures in different developmental stages and accordingly providing an important resource for the epigenetic and developmental studies. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  17. Integration of Wind Energy Systems into Power Engineering Education Program at UW-Madison

    Energy Technology Data Exchange (ETDEWEB)

    Venkataramanan, Giri [Univ. of Wisconsin, Madison, WI (United States); Lesieutre, Bernard [Univ. of Wisconsin, Madison, WI (United States); Jahns, Thomas [Univ. of Wisconsin, Madison, WI (United States); Desai, Ankur R [Univ. of Wisconsin, Madison, WI (United States)

    2012-09-01

    This project has developed an integrated curriculum focused on the power engineering aspects of wind energy systems that builds upon a well-established graduate educational program at UW- Madison. Five new courses have been developed and delivered to students. Some of the courses have been offered on multiple occasions. The courses include: Control of electric drives for Wind Power applications, Utility Applications of Power Electronics (Wind Power), Practicum in Small Wind Turbines, Utility Integration of Wind Power, and Wind and Weather for Scientists and Engineers. Utility Applications of Power Electronics (Wind Power) has been provided for distance education as well as on-campus education. Several industrial internships for students have been organized. Numerous campus seminars that provide discussion on emerging issues related to wind power development have been delivered in conjunction with other campus events. Annual student conferences have been initiated, that extend beyond wind power to include sustainable energy topics to draw a large group of stakeholders. Energy policy electives for engineering students have been identified for students to participate through a certificate program. Wind turbines build by students have been installed at a UW-Madison facility, as a test-bed. A Master of Engineering program in Sustainable Systems Engineering has been initiated that incorporates specializations that include in wind energy curricula. The project has enabled UW-Madison to establish leadership at graduate level higher education in the field of wind power integration with the electric grid.

  18. Open pre-schools at integrated health services - A program theory

    Directory of Open Access Journals (Sweden)

    Agneta Abrahamsson

    2013-04-01

    Full Text Available Introduction: Family centres in Sweden are integrated services that reach all prospective parents and parents with children up to their sixth year, because of the co-location of the health service with the social service and the open pre-school. The personnel on the multi-professional site work together to meet the needs of the target group. The article explores a program theory focused on the open pre-schools at family centres.Method: A multi-case design is used and the sample consists of open pre-schools at six family centres. The hypothesis is based on previous research and evaluation data. It guides the data collection which is collected and analysed stepwise. Both parents and personnel are interviewed individually and in groups at each centre.Findings: The hypothesis was expanded to a program theory. The compliance of the professionals was the most significant element that explained why the open access service facilitated positive parenting. The professionals act in a compliant manner to meet the needs of the children and parents as well as in creating good conditions for social networking and learning amongst the parents. Conclusion: The compliance of the professionals in this program theory of open pre-schools at family centres can be a standard in integrated and open access services, whereas the organisation form can vary. The best way of increasing the number of integrative services is to support and encourage professionals that prefer to work in a compliant manner.

  19. Open pre-schools at integrated health services - A program theory

    Directory of Open Access Journals (Sweden)

    Agneta Abrahamsson

    2013-04-01

    Full Text Available Introduction: Family centres in Sweden are integrated services that reach all prospective parents and parents with children up to their sixth year, because of the co-location of the health service with the social service and the open pre-school. The personnel on the multi-professional site work together to meet the needs of the target group. The article explores a program theory focused on the open pre-schools at family centres. Method: A multi-case design is used and the sample consists of open pre-schools at six family centres. The hypothesis is based on previous research and evaluation data. It guides the data collection which is collected and analysed stepwise. Both parents and personnel are interviewed individually and in groups at each centre. Findings: The hypothesis was expanded to a program theory. The compliance of the professionals was the most significant element that explained why the open access service facilitated positive parenting. The professionals act in a compliant manner to meet the needs of the children and parents as well as in creating good conditions for social networking and learning amongst the parents. Conclusion: The compliance of the professionals in this program theory of open pre-schools at family centres can be a standard in integrated and open access services, whereas the organisation form can vary. The best way of increasing the number of integrative services is to support and encourage professionals that prefer to work in a compliant manner.

  20. Epistemology, development, and integrity in a science education professional development program

    Science.gov (United States)

    Hancock, Elizabeth St. Petery

    This research involved interpretive inquiry to understand changes in the notion of "self" as expressed by teachers recently enrolled as graduate students in an advanced degree program in science education at Florida State University. Teachers work in a context that integrates behavior, social structure, culture, and intention. Within this context, this study focused on the intentional realm that involves interior understandings, including self-epistemology, professional self-identity, and integrity. Scholarship in adult and teacher development, especially ways of knowing theory, guided my efforts to understand change in these notions of self. The five participants in this study were interviewed in depth to explore their "self"-related understandings in detail. The other primary data sources were portfolios and work the participants submitted as part of the program. Guided by a constructivist methodology, I used narrative inquiry and grounded theory to conduct data analysis. As learners and teachers, these individuals drew upon epistemological orientations emphasizing a procedural orientation to knowledge. They experienced varying degrees of interior and exterior development in self and epistemology. They created integrity in their efforts to align their intentions with their actions with a dynamic relationship to context. This study suggests that professional development experiences in science education include consideration of the personal and the professional, recognize and honor differing perspectives, facilitate development, and assist individuals to recognize and articulate their integrity.

  1. Impact of a Post-Discharge Integrated Disease Management Program on COPD Hospital Readmissions.

    Science.gov (United States)

    Russo, Ashlee N; Sathiyamoorthy, Gayathri; Lau, Chris; Saygin, Didem; Han, Xiaozhen; Wang, Xiao-Feng; Rice, Richard; Aboussouan, Loutfi S; Stoller, James K; Hatipoğlu, Umur

    2017-11-01

    Readmission following a hospitalization for COPD is associated with significant health-care expenditure. A multicomponent COPD post-discharge integrated disease management program was implemented at the Cleveland Clinic to improve the care of patients with COPD and reduce readmissions. This retrospective study reports our experience with the program. Groups of subjects who were exposed to different components of the program were compared regarding their readmission rates. Multivariate logistic regression analysis was performed to build predictive models for 30- and 90-d readmission. One hundred sixty subjects completed a 90-d follow-up, of which, 67 attended the exacerbation clinic, 16 subjects received care coordination, 51 subjects completed both, and 26 subjects did not participate in any component despite referral. Thirty- and 90-d readmission rates for the entire group were 18.1 and 46.2%, respectively. Thirty- and 90-d readmission rates for the individual groups were: exacerbation clinic, 11.9 and 35.8%; care coordination, 25.0 and 50.0%; both, 19.6 and 41.2%; and neither, 26.9 and 80.8%, respectively. The model with the best predictive ability for 30-d readmission risk included the number of hospitalizations within the previous year and use of noninvasive ventilation (C statistic of 0.84). The model for 90-d readmission risk included receiving any component of the post-discharge integrated disease management program, the number of hospitalizations, and primary care physician visits within the previous year (C statistic of 0.87). Receiving any component of a post-discharge integrated disease management program was associated with reduced 90-d readmission rate. Previous health-care utilization and lung function impairment were strong predictors of readmission. Copyright © 2017 by Daedalus Enterprises.

  2. The Efficiency of an Integrated Program Using Falconry to Deter Gulls from Landfills

    Directory of Open Access Journals (Sweden)

    Ericka Thiériot

    2015-04-01

    Full Text Available Gulls are commonly attracted to landfills, and managers are often required to implement cost-effective and socially accepted deterrence programs. Our objective was to evaluate the effectiveness of an intensive program that integrated the use of trained birds of prey, pyrotechnics, and playback of gull distress calls at a landfill located close to a large ring-billed gull (Larus delawarensis colony near Montreal, Quebec, Canada. We used long-term survey data on bird use of the landfill, conducted behavioral observations of gulls during one season and tracked birds fitted with GPS data loggers. We also carried out observations at another landfill located farther from the colony, where less refuse was brought and where a limited culling program was conducted. The integrated program based on falconry resulted in a 98% decrease in the annual total number of gulls counted each day between 1995 and 2014. A separate study indicated that the local breeding population of ring-billed gulls increased and then declined during this period but remained relatively large. In 2010, there was an average (±SE of 59 ± 15 gulls/day using the site with falconry and only 0.4% ± 0.2% of these birds were feeding. At the other site, there was an average of 347 ± 55 gulls/day and 13% ± 3% were feeding. Twenty-two gulls tracked from the colony made 41 trips towards the landfills: twenty-five percent of the trips that passed by the site with falconry resulted in a stopover that lasted 22 ± 7 min compared to 85% at the other landfill lasting 63 ± 15 min. We concluded that the integrated program using falconry, which we consider more socially acceptable than selective culling, was effective in reducing the number of gulls at the landfill.

  3. The experience of primary care providers with an integrated mental health care program in safety-net clinics.

    Science.gov (United States)

    Bentham, Wayne D; Ratzliff, Anna; Harrison, David; Chan, Ya-Fen; Vannoy, Steven; Unützer, Jürgen

    2015-01-01

    Primary care providers participating in a statewide implementation of an integrated mental health care program for "safety-net" patients in primary care clinics were surveyed to elicit their experiences and level of satisfaction. Quantitative analyses were performed to identify respondent characteristics and satisfaction with the program. Qualitative analyses were done to identify common themes in response to the question "How could psychiatric consultation [in the program] be improved?" Primary care providers were generally satisfied with the integrated mental health care program and raised several concerns that suggest important principles for successful future implementations of these types of programs.

  4. Integrating prevention of mother-to-child HIV transmission programs to improve uptake: a systematic review.

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    Lorainne Tudor Car

    Full Text Available BACKGROUND: We performed a systematic review to assess the effect of integrated perinatal prevention of mother-to-child transmission of HIV interventions compared to non- or partially integrated services on the uptake in low- and middle-income countries. METHODS: We searched for experimental, quasi-experimental and controlled observational studies in any language from 21 databases and grey literature sources. RESULTS: Out of 28 654 citations retrieved, five studies met our inclusion criteria. A cluster randomized controlled trial reported higher probability of nevirapine uptake at the labor wards implementing HIV testing and structured nevirapine adherence assessment (RRR 1.37, bootstrapped 95% CI, 1.04-1.77. A stepped wedge design study showed marked improvement in antiretroviral therapy (ART enrolment (44.4% versus 25.3%, p<0.001 and initiation (32.9% versus 14.4%, p<0.001 in integrated care, but the median gestational age of ART initiation (27.1 versus 27.7 weeks, p = 0.4, ART duration (10.8 versus 10.0 weeks, p = 0.3 or 90 days ART retention (87.8% versus 91.3%, p = 0.3 did not differ significantly. A cohort study reported no significant difference either in the ART coverage (55% versus 48% versus 47%, p = 0.29 or eight weeks of ART duration before the delivery (50% versus 42% versus 52%; p = 0.96 between integrated, proximal and distal partially integrated care. Two before and after studies assessed the impact of integration on HIV testing uptake in antenatal care. The first study reported that significantly more women received information on PMTCT (92% versus 77%, p<0.001, were tested (76% versus 62%, p<0.001 and learned their HIV status (66% versus 55%, p<0.001 after integration. The second study also reported significant increase in HIV testing uptake after integration (98.8% versus 52.6%, p<0.001. CONCLUSION: Limited, non-generalizable evidence supports the effectiveness of integrated PMTCT programs. More research measuring coverage and

  5. Evaluation of a Integral School-Sports Program first year development

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    González Pascual, Marta

    2012-01-01

    Full Text Available This paper provides the results of the evaluation carried out at the end of the first year of implementation of an integrated municipal scholar-sports project, especially focusing on the satisfaction ratings provided by various stakeholders (students, parents, teachers and monitors. A questionnaire was designed «ad hoc» for each of the four people involved in the development of the program: students, families, teachers and monitors. It was applied in the last two weeks of the program. Data were analyzed with SPSS 15.0. The results show that, overall, the integrated program of scholar-sport has generated very high satisfaction rates in all participating groups. We analyze the strengths and weaknesses of the project on the following aspects: the Friday meetings, use of facilities, attitude and methodology used by the monitors, an approach that is given to exercise regularly (AFD and information received about the project. Conclusion: The performance evaluation of the program shows a very high satisfaction rate in all the agents involved, although there are some weaknesses that should be improved in the following application

  6. Alberta Healthy Living Program--a model for successful integration of chronic disease management services.

    Science.gov (United States)

    Morrin, Louise; Britten, Judith; Davachi, Shahnaz; Knight, Holly

    2013-08-01

    The most common presentation of chronic disease is multimorbidity. Disease management strategies are similar across most chronic diseases. Given the prevalence of multimorbidity and the commonality in approaches, fragmented single disease management must be replaced with integrated care of the whole person. The Alberta Healthy Living Program, a community-based chronic disease management program, supports adults with, or at risk for, chronic disease to improve their health and well being. Participants gain confidence and skills in how to manage their chronic disease(s) by learning to understand their health condition, make healthy eating choices, exercise safely and cope emotionally. The program includes 3 service pillars: disease-specific and general health patient education, disease-spanning supervised exercise and Better Choices, Better Health(TM) self-management workshops. Services are delivered in the community by an interprofessional team and can be tailored to target specific diverse and vulnerable populations, such as Aboriginal, ethno-cultural and francophone groups and those experiencing homelessness. Programs may be offered as a partnership between Alberta Health Services, primary care and community organizations. Common standards reduce provincial variation in care, yet maintain sufficient flexibility to meet local and diverse needs and achieve equity in care. The model has been implemented successfully in 108 communities across Alberta. This approach is associated with reduced acute care utilization and improved clinical indicators, and achieves efficiencies through an integrated, disease-spanning patient-centred approach. Crown Copyright © 2013. Published by Elsevier Inc. All rights reserved.

  7. STARS: An Integrated, Multidisciplinary, Finite-Element, Structural, Fluids, Aeroelastic, and Aeroservoelastic Analysis Computer Program

    Science.gov (United States)

    Gupta, K. K.

    1997-01-01

    A multidisciplinary, finite element-based, highly graphics-oriented, linear and nonlinear analysis capability that includes such disciplines as structures, heat transfer, linear aerodynamics, computational fluid dynamics, and controls engineering has been achieved by integrating several new modules in the original STARS (STructural Analysis RoutineS) computer program. Each individual analysis module is general-purpose in nature and is effectively integrated to yield aeroelastic and aeroservoelastic solutions of complex engineering problems. Examples of advanced NASA Dryden Flight Research Center projects analyzed by the code in recent years include the X-29A, F-18 High Alpha Research Vehicle/Thrust Vectoring Control System, B-52/Pegasus Generic Hypersonics, National AeroSpace Plane (NASP), SR-71/Hypersonic Launch Vehicle, and High Speed Civil Transport (HSCT) projects. Extensive graphics capabilities exist for convenient model development and postprocessing of analysis results. The program is written in modular form in standard FORTRAN language to run on a variety of computers, such as the IBM RISC/6000, SGI, DEC, Cray, and personal computer; associated graphics codes use OpenGL and IBM/graPHIGS language for color depiction. This program is available from COSMIC, the NASA agency for distribution of computer programs.

  8. Evidence and Feasibility of Implementing an Integrated Wellness Program in Northeast Georgia.

    Science.gov (United States)

    Flanigan, Amber; Salm Ward, Trina

    2017-08-01

    Evidence for the connection between physical and mental health is growing, as is interest in providing a holistic, mind-body approach to improving mental health and wellness. A needs assessment in northeast Georgia identified several regional health priorities, including mental health and substance abuse, access to care, and cardiovascular health. The study's purpose is threefold: to (1) review evidence for integrated mind-body wellness services, (2) explore the feasibility of implementing wellness services in a small mental health agency serving northeast Georgia, and (3) conduct a brief survey assessing interest in a wellness program. The literature search identified articles within the past 10 years with these key words: "yoga," "mental health," "wellness program," "complementary alternative medicine," "tai chi," "mindfulness," "meditation," and "nutrition." The survey was distributed to the agency's affiliates. The literature review identified strong evidence for an integrated mind-body wellness program that includes yoga, tai chi, mindfulness meditation, and nutrition education. Among 73 survey respondents, 86 percent indicated interest in wellness services, and 85 percent agreed that wellness services are important to mental health and well-being. Authors suggest a model to incorporate a holistic wellness program to complement mental health services and help facilitate physical and mental health. © 2017 National Association of Social Workers.

  9. THE INTEGRATION ARTICULATION BETWEEN THE EDUCATION AND HEALTH ACTIONS IN THE FAMILY HEALTH PROGRAM – PSF

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    Cesar Cavalcanti da Silva

    2006-04-01

    Full Text Available ABSTRACT: The article discusses the practical actions of a team of the Family Health Program-PSF in a city of the Northeastern Brazilian region and, it reveals the lack of integration/articulation of those actions with the educational dimension. The disarticulation of the team members’ knowledge of health on the theoretical, methodological and philosophical principles of PSF is pointed as one of the determinant of the little involvement of the team work with the educational area. the analysis of the collected data was accomplished through the technique of the critical Analysis of the speeches that led to the empiric category: contradiction theoretical x practice in the actions of the health teams of the Family Health Program. KEY WORDS: Health Education, Family Health Program; Public Health Nursing.

  10. Treating prison inmates with co-occurring disorders: an integrative review of existing programs.

    Science.gov (United States)

    Edens, J F; Peters, R H; Hills, H A

    1997-01-01

    The tremendous growth in state and federal correctional populations has focused greater attention on the needs of mentally ill and substance abusing inmates. Although an estimated 3-11% of prison inmates have co-occurring mental health (psychotic and major mood) disorders and substance abuse disorders, few treatment programs are described in the literature and there is little available information regarding effective treatment strategies for this population. The current study provides an integrative review of seven 'dual diagnosis' treatment programs that recently have been developed in state and federal prisons. Many of these have evolved from existing substance abuse treatment programs and approaches. Key program components include an extended assessment period, orientation/motivational activities, psychoeducational groups, cognitive-behavioral interventions such as restructuring of 'criminal thinking errors', self-help groups, medication monitoring, relapse prevention, and transition into institution or community-based aftercare facilities. Many programs use therapeutic community approaches that are modified to provide (a) greater individual counseling and support, (b) less confrontation, (c) smaller staff caseloads, and (d) cross-training of staff. Research is underway in three of the seven sites to examine the effectiveness of these new programs.

  11. [Multicenter program for the integrated care of newborns with perinatal hypoxic-ischemic insult (ARAHIP)].

    Science.gov (United States)

    Arnáez, J; Vega, C; García-Alix, A; Gutiérrez, E P; Caserío, S; Jiménez, M P; Castañón, L; Esteban, I; Hortelano, M; Hernández, N; Serrano, M; Prada, T; Diego, P; Barbadillo, F

    2015-03-01

    Newborns with perinatal indicators of a potential hypoxic-ischemic event require an integrated care in order to control the aggravating factors of brain damage, and the early identification of candidates for hypothermia treatment. The application of a prospective, populational program that organizes and systematizes medical care during the first 6 hours of life to all newborns over 35 weeks gestational age born with indicators of a perinatal hypoxic-ischemic insult. The program includes 12 hospitals (91,217 m(2)); two level i centers, five level ii centers, and five level iii hospitals. The program establishes four protocols: a) detection of the newborn with a potential hypoxic-ischemic insult, b) surveillance of the neurological repercussions and other organ involvement, c) control and treatment of complications, d) procedures and monitoring during transport. From June 2011 to June 2013, 213 of 32325 newborns above 35 weeks gestational age met the criteria of a potential hypoxic-ischemic insult (7.4/1000), with 92% of them being cared for following the program specifications. Moderate-severe hypoxic-ischemic encephalopathy was diagnosed in 33 cases (1/1,000), and 31 out of the 33 received treatment with hypothermia (94%). The program for the Integrated Care of Newborns with Perinatal Hypoxic-Ischemic Insult has led to providing a comprehensive care to the newborns with a suspected perinatal hypoxic-ischemic insult. Aggravators of brain damage have been controlled, and cases of moderate-severe hypoxic-ischemic encephalopathy have been detected, allowing the start of hypothermia treatment within the first six hours of life. Populational programs are fundamental to reducing the mortality and morbidity of hypoxic-ischemic encephalopathy. Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.

  12. Pharmacy characteristics associated with the provision of medication management services within an integrated care management program.

    Science.gov (United States)

    Smith, Megan G; Shea, Christopher M; Brown, Patrick; Wines, Kristen; Farley, Joel F; Ferreri, Stefanie P

    To examine pharmacy operational and personnel characteristics that influence engagement in providing a community pharmacy medication management service within a statewide integrated care management program. Before the program launch, all of the pharmacies were surveyed to collect demographic, operational, and personnel characteristics such as weekly prescription volume and number of staff, respectively. Those data were then compared with engagement in the program. Engagement was defined as providing initial comprehensive medication review as part of the medication management service. Three months after program launch, pharmacies were dichotomized as consistently engaged or inconsistently engaged. Data were analyzed with the use of descriptive statistics and chi-square and t tests to test for statistical significance between consistent and inconsistent engagement groups. A baseline survey was collected for all 123 pharmacies who joined the integrated care management program. After the first 3 months, 50 pharmacies were consistently engaged in the program. Compared with inconsistently engaged pharmacies, consistently engaged pharmacies employed more full-time pharmacists (mean 2.1 vs. 1.8; P = 0.05) and more full-time technicians (mean 4.0 vs. 3.0; P <0.01), allocated more nondispensing hours for pharmacists (88% vs 60%; P <0.01), were more likely to employ a dedicated clinical pharmacist (20% vs 5%; P = 0.013), and hosted more pharmacy residents (78% vs 22%; P = 0.02). Years of pharmacy operation (P = 0.05) and pharmacy store type (P = 0.05) also were significantly associated with level of engagement. Neither prescription volume dispensed per week, number of hours of pharmacist overlap, nor hosting pharmacy students was statistically different between consistent and inconsistent pharmacies. Engagement in clinical activities in community pharmacy appears to improve with adequate staffing, availability of time for nondispensing activities, and having 1 or more

  13. Working Together: Building Successful Policy and Program Partnerships for Immigrant Integration

    Directory of Open Access Journals (Sweden)

    Els de Graauw

    2017-03-01

    Full Text Available Supporting and investing in the integration of immigrants and their children is critically important to US society. Successful integration contributes to the nation’s economic vitality, its civic and political health, and its cultural diversity. But although the United States has a good track record on immigrant integration, outcomes could be better. A national, coherent immigrant integration policy infrastructure is needed. This infrastructure can build on long-standing partnerships between civil society and US public institutions. Such partnerships, advanced under Republican- and Democratic-led administrations, were initially established to facilitate European immigrants’ integration in large American cities, and later extended to help refugees fleeing religious persecution and war. In the twenty-first century, we must expand this foundation by drawing on the growing activism by cities and states, new civil society initiatives, and public-private partnerships that span the country. A robust national integration policy infrastructure must be vertically integrated to include different levels of government and horizontally applied across public and private sector actors and different types of immigrant destinations. The resultant policy should leverage public-private partnerships, drawing on the energy, ideas, and work of community-based nonprofit organizations as well as the leadership and support of philanthropy, business, education, faith-based, and other institutions. A new coordinating office to facilitate interagency cooperation is needed in the executive branch; the mandate and programs of the Office of Refugee Resettlement need to be secured and where possible expanded; the outreach and coordinating role of the Office of Citizenship needs to be extended, including through a more robust grant program to community-based organizations; and Congress needs to develop legislation and appropriate funding for a comprehensive integration

  14. Integrated Optimization of Long-Range Underwater Signal Detection, Feature Extraction, and Classification for Nuclear Treaty Monitoring

    NARCIS (Netherlands)

    Tuma, M.; Rorbech, V.; Prior, M.; Igel, C.

    2016-01-01

    We designed and jointly optimized an integrated signal processing chain for detection and classification of long-range passive-acoustic underwater signals recorded by the global geophysical monitoring network of the Comprehensive Nuclear-Test-Ban Treaty Organization. Starting at the level of raw

  15. Exploring Features of Integrative Teaching through a Microanalysis of Connection-Making Processes in a Health Sciences Curriculum

    Science.gov (United States)

    Hooper, Barbara R.; Greene, David; Sample, Pat L.

    2014-01-01

    The interconnected nature of knowledge in the health sciences is not always reflected in how curricula, courses, and learning activities are designed. Thus have scholars advocated for more explicit attention to connection-making, or integration, in teaching and learning. However, conceptual and empirical work to guide such efforts is limited. This…

  16. Indicators of integration of oncology and palliative care programs: an international consensus

    Science.gov (United States)

    Hui, D.; Bansal, S.; Strasser, F.; Morita, T.; Caraceni, A.; Davis, M.; Cherny, N.; Kaasa, S.; Currow, D.; Abernethy, A.; Nekolaichuk, C.; Bruera, E.

    2015-01-01

    Background Recently, the concept of integrating oncology and palliative care has gained wide professional and scientific support; however, a global consensus on what constitutes integration is unavailable. We conducted a Delphi Survey to develop a consensus list of indicators on integration of specialty palliative care and oncology programs for advanced cancer patients in hospitals with ≥100 beds. Methods International experts on integration rated a list of indicators on integration over three iterative rounds under five categories: clinical structure, processes, outcomes, education, and research. Consensus was defined a priori by an agreement of ≥70%. Major criteria (i.e. most relevant and important indicators) were subsequently identified. Results Among 47 experts surveyed, 46 (98%), 45 (96%), and 45 (96%) responded over the three rounds. Nineteen (40%) were female, 24 (51%) were from North America, and 14 (30%) were from Europe. Sixteen (34%), 7 (15%), and 25 (53%) practiced palliative care, oncology, and both specialties, respectively. After three rounds of deliberation, the panelists reached consensus on 13 major and 30 minor indicators. Major indicators included two related to structure (consensus 95%–98%), four on processes (88%–98%), three on outcomes (88%–91%), and four on education (93%–100%). The major indicators were considered to be clearly stated (9.8/10), objective (9.4/10), amenable to accurate coding (9.5/10), and applicable to their own countries (9.4/10). Conclusions Our international experts reached broad consensus on a list of indicators of integration, which may be used to identify centers with a high level of integration, and facilitate benchmarking, quality improvement, and research. PMID:26088196

  17. Sperm chromatin maturity and integrity correlated to zygote development in ICSI program.

    Science.gov (United States)

    Asmarinah; Syauqy, Ahmad; Umar, Liya Agustin; Lestari, Silvia Werdhy; Mansyur, Eliza; Hestiantoro, Andon; Paradowszka-Dogan, Agnieszka

    2016-10-01

    This study aimed to evaluate sperm chromatin maturity and integrity of that injected into good-quality oocytes in an in vitro fertilization-intra cytoplasmic sperm injection (IVF-ICSI) program. A cut-off value of sperm chromatin maturity and integrity was developed as a function of their correlation to the zygote development, i.e., embryo formation and cleavage rate. The study assessed sperm chromatin maturity using aniline blue (AB) staining, whereas toluidine blue (TB) staining was used to assess sperm chromatin integrity. Ejaculates from 59 patients undergoing ICSI and 46 fertile normozoospermic donors for determination of normal values of sperm chromatin status were used in this study. Embryo formation and cleavage rates were observed for the period of 3 days after ICSI. There was a significant difference in the percentage of sperm with mature chromatin between ejaculate from ICSI patients and fertile donor (p=0.020); while there was no significant difference in sperm chromatin integrity of both samples (p=0.120). There was no significant correlation between sperm chromatin maturity and either embryo formation or cleavage rate; as well as sperm chromatin integrity to both parameters of zygote development (p>0.05). Furthermore, we found that the cut-off value of sperm chromatin maturity and integrity of the fertile normozoospermic ejaculates were 87.2% and 80.2%, respectively. Using the cut-offs, we found that low sperm chromatin maturity at the level of chromatin integrity at the level of chromatin (AB<87% and TB<80%, respectively), could affect zygote development following ICSI. AB: aniline blue; CMA3: chromomycin A3; ICSI: intra cytoplasmic sperm injection; IVF: in vitro fertilization; PBS: phosphate buffer saline; SPSS: Statistical Package for Social Science; TB: toluidine blue; WHO: World Health Organization.

  18. Mapping the Consequences of Impaired Synaptic Plasticity in Schizophrenia through Development: An Integrative Model for Diverse Clinical Features.

    Science.gov (United States)

    Forsyth, Jennifer K; Lewis, David A

    2017-10-01

    Schizophrenia is associated with alterations in sensory, motor, and cognitive functions that emerge before psychosis onset; identifying pathogenic processes that can account for this multi-faceted phenotype remains a challenge. Accumulating evidence suggests that synaptic plasticity is impaired in schizophrenia. Given the role of synaptic plasticity in learning, memory, and neural circuit maturation, impaired plasticity may underlie many features of the schizophrenia syndrome. Here, we summarize the neurobiology of synaptic plasticity, review evidence that plasticity is impaired in schizophrenia, and explore a framework in which impaired synaptic plasticity interacts with brain maturation to yield the emergence of sensory, motor, cognitive, and psychotic features at different times during development in schizophrenia. Key gaps in the literature and future directions for testing this framework are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Integrating an internet-mediated walking program into family medicine clinical practice: a pilot feasibility study.

    Science.gov (United States)

    Goodrich, David E; Buis, Lorraine R; Janney, Adrienne W; Ditty, Megan D; Krause, Christine W; Zheng, Kai; Sen, Ananda; Strecher, Victor J; Hess, Michael L; Piette, John D; Richardson, Caroline R

    2011-06-24

    Regular participation in physical activity can prevent many chronic health conditions. Computerized self-management programs are effective clinical tools to support patient participation in physical activity. This pilot study sought to develop and evaluate an online interface for primary care providers to refer patients to an Internet-mediated walking program called Stepping Up to Health (SUH) and to monitor participant progress in the program. In Phase I of the study, we recruited six pairs of physicians and medical assistants from two family practice clinics to assist with the design of a clinical interface. During Phase II, providers used the developed interface to refer patients to a six-week pilot intervention. Provider perspectives were assessed regarding the feasibility of integrating the program into routine care. Assessment tools included quantitative and qualitative data gathered from semi-structured interviews, surveys, and online usage logs. In Phase I, 13 providers used SUH and participated in two interviews. Providers emphasized the need for alerts flagging patients who were not doing well and the ability to review participant progress. Additionally, providers asked for summary views of data across all enrolled clinic patients as well as advertising materials for intervention recruitment. In response to this input, an interface was developed containing three pages: 1) a recruitment page, 2) a summary page, and 3) a detailed patient page. In Phase II, providers used the interface to refer 139 patients to SUH and 37 (27%) enrolled in the intervention. Providers rarely used the interface to monitor enrolled patients. Barriers to regular use of the intervention included lack of integration with the medical record system, competing priorities, patient disinterest, and physician unease with exercise referrals. Intention-to-treat analyses showed that patients increased walking by an average of 1493 steps/day from pre- to post-intervention (t = (36) = 4.13, p

  20. Starting and resourcing family and internal medicine residency programs as integral mission

    Directory of Open Access Journals (Sweden)

    Stephen P Merry

    2016-01-01

    Full Text Available Graduate medical education is an excellent means of building the capacity of health care systems in low and middle Income Countries (LMIC and a growing way for physicians in the U.S to get involved in integral mission – the proclamation and demonstration of the Gospel. This white paper purposes to provide a “best practices” recommendations on family and internal medicine (“medical” residency program development in majority world settings. An expert panel of residency educators convened in November 2015 at the Global Missions Health Conference (GMHC in Louisville, Kentucky and through an iterative process identified themes that were then further defined and clarified by medical residency faculty unable to be present. Participants largely agreed that integration and cooperation with the country’s Ministry of Health (MOH is essential for sustainable residency development. Recognition of family medicine as a specialty will enable graduates to succeed in the country’s physician job market and health systems leadership. Recognition by the national church of the unique needs of their mission hospitals’ educational programs to control their revenue in order to fund their programs’ growth and development exemplifies the common wisdom to provide authority and resources where responsibility for good outcomes is expected. Co-training of general surgeons and medical residents who can provide essential surgical call coverage may lead to on-going synergies. Teaching by medical and surgical subspecialists is essential in medical residencies to provide the depth of instruction residents need to develop as excellent clinicians. Dependable scheduling of their specialty instruction allows residency program directors to assure inclusion of their content in the residency curriculum. In summary, participants agreed that teaching in medical residency programs in LMIC present excellent opportunities for national and expat Christian physician educators

  1. Beyond beach width: Steps toward identifying and integrating ecological envelopes with geomorphic features and datums for sandy beach ecosystems

    Science.gov (United States)

    Dugan, Jenifer E.; Hubbard, David M.; Quigley, Brenna J.

    2013-10-01

    Our understanding of ecological responses to climatic and anthropogenic forcing lags far behind that of physical or geomorphic responses for beach ecosystems. Reconciling geomorphic features of beaches with ecological features, such as intertidal zones and mobile biota that are not described by beach width alone, could help address this issue. First, although intertidal zones characterized by distinct groups of mobile burrowing animals are described for beaches, the locations and elevations of these zones do not coincide with standard shoreline datums. Second, intertidal zonation on beaches is extremely dynamic due to the combination of unstable sandy substrate and a highly mobile biota; shifting strongly with tides, waves, storms, and beach conditions. We propose that beach biota use ecological "envelopes" of cross-shore habitat to cope with constantly changing beach conditions. We estimated the extent of these "envelopes" for a variety of taxa on tidal to daily, semi-lunar and seasonal to annual time scales, using literature values on cross-shore animal movements and a field study of the positions of intertidal beds of two species of typical mid and upper shore beach invertebrates. Daily or tidal cross-shore movement varied most (1 m to 100 m) with daily "envelopes" covering 7% to 85% of the available beach width. Semi-lunar movement (12 m) and envelopes (28%) were relatively small, while estimated annual "envelopes" were large, averaging 61% of beach width. The large scope of annual ecological envelopes relative to beach widths reflects how intertidal animals escape seasonally extreme or episodically harsh conditions. Intertidal bed positions of a talitrid amphipod and an opheliid polychaete correlated well with selected beach features in our field study suggesting that incorporation of ecological envelopes in models of shoreline evolution may be feasible. Describing ecological zones in terms of more dynamic shoreline features, such as total water level (TWL

  2. Perceptual Confusions Among Consonants, Revisited: Cross-Spectral Integration of Phonetic-Feature Information and Consonant Recognition

    DEFF Research Database (Denmark)

    Christiansen, Thomas Ulrich; Greenberg, Steven

    2012-01-01

    -spectral summation. This difference is mirrored in a measure of error-pattern similarity across bands—Symmetric Redundancy. Consonants, as well as Voicing and Manner, share a moderate degree of redundancy between bands. In contrast, the cross-spectral redundancy associated with Place is close to zero, which means....... Adding a third band increases the IT by an amount somewhat less than predicted by linear cross-spectral integration (i.e., a compressive function). In contrast, for Place of Articulation, the IT gained through addition of a second or third slit is far more than predicted by linear, cross...... for why conventional cross-spectral integration speech models, such as the Articulation Index, Speech Intelligibility Index, and the Speech Transmission Index do not predict intelligibility and segment recognition well under certain conditions (e.g., discontiguous frequency bands, audio-visual speech)....

  3. Maternal substance use and integrated treatment programs for women with substance abuse issues and their children: a meta-analysis.

    Science.gov (United States)

    Milligan, Karen; Niccols, Alison; Sword, Wendy; Thabane, Lehana; Henderson, Joanna; Smith, Ainsley; Liu, Jennifer

    2010-09-01

    The rate of women with substance abuse issues is increasing. Women present with a unique constellation of risk factors and presenting needs, which may include specific needs in their role as mothers. Numerous integrated programs (those with substance use treatment and pregnancy, parenting, or child services) have been developed to specifically meet the needs of pregnant and parenting women with substance abuse issues. This synthesis and meta-analysis reviews research in this important and growing area of treatment. We searched PsycINFO, MedLine, PubMed, Web of Science, EMBASE, Proquest Dissertations, Sociological Abstracts, and CINAHL and compiled a database of 21 studies (2 randomized trials, 9 quasi-experimental studies, 10 cohort studies) of integrated programs published between 1990 and 2007 with outcome data on maternal substance use. Data were summarized and where possible, meta-analyses were performed, using standardized mean differences (d) effect size estimates. In the two studies comparing integrated programs to no treatment, effect sizes for urine toxicology and percent using substances significantly favored integrated programs and ranged from 0.18 to 1.41. Studies examining changes in maternal substance use from beginning to end of treatment were statistically significant and medium sized. More specifically, in the five studies measuring severity of drug and alcohol use, the average effect sizes were 0.64 and 0.40, respectively. In the four cohort studies of days of use, the average effect size was 0.52. Of studies comparing integrated to non-integrated programs, four studies assessed urine toxicology and two assessed self-reported abstinence. Overall effect sizes for each measure were not statistically significant (d = -0.09 and 0.22, respectively). Findings suggest that integrated programs are effective in reducing maternal substance use. However, integrated programs were not significantly more effective than non-integrated programs. Policy

  4. Plagiarism, Cheating and Research Integrity: Case Studies from a Masters Program in Peru.

    Science.gov (United States)

    Carnero, Andres M; Mayta-Tristan, Percy; Konda, Kelika A; Mezones-Holguin, Edward; Bernabe-Ortiz, Antonio; Alvarado, German F; Canelo-Aybar, Carlos; Maguiña, Jorge L; Segura, Eddy R; Quispe, Antonio M; Smith, Edward S; Bayer, Angela M; Lescano, Andres G

    2017-08-01

    Plagiarism is a serious, yet widespread type of research misconduct, and is often neglected in developing countries. Despite its far-reaching implications, plagiarism is poorly acknowledged and discussed in the academic setting, and insufficient evidence exists in Latin America and developing countries to inform the development of preventive strategies. In this context, we present a longitudinal case study of seven instances of plagiarism and cheating arising in four consecutive classes (2011-2014) of an Epidemiology Masters program in Lima, Peru, and describes the implementation and outcomes of a multifaceted, "zero-tolerance" policy aimed at introducing research integrity. Two cases involved cheating in graded assignments, and five cases correspond to plagiarism in the thesis protocol. Cases revealed poor awareness of high tolerance to plagiarism, poor academic performance, and widespread writing deficiencies, compensated with patchwriting and copy-pasting. Depending on the events' severity, penalties included course failure (6/7) and separation from the program (3/7). Students at fault did not engage in further plagiarism. Between 2011 and 2013, the Masters program sequentially introduced a preventive policy consisting of: (i) intensified research integrity and scientific writing education, (ii) a stepwise, cumulative writing process; (iii) honor codes; (iv) active search for plagiarism in all academic products; and (v) a "zero-tolerance" policy in response to documented cases. No cases were detected in 2014. In conclusion, plagiarism seems to be widespread in resource-limited settings and a greater response with educational and zero-tolerance components is needed to prevent it.

  5. Unit and integration testing of Lustre programs: a case study from the nuclear industry

    Energy Technology Data Exchange (ETDEWEB)

    Thevenod-Fosse, P

    1998-12-31

    LUSTRE belongs to the class of synchronous data flow languages which have been designed for programming reactive and real-time systems having safety-critical requirements. It is implemented in the SCADE tool. SCADE is a software development environment for real-time systems which consists of a graphical and textual editor, and a C code generator. In previous work, a testing approach specific to LUSTRE programs has been defined, which may be applied at either the unit or integration testing levels of a gradual testing process. The paper reports on an industrial case study we have performed to exemplify the feasibility of the testing strategy. The software module, called SRIC (Source Range Instrumentation channel), was developed by SCHNEIDER ELECTRIC in the SCADE environment. SRIC is extracted from a monitoring software system of a nuclear reactor: it approximates 2600 lines of C code automatically generated by SCADE. Section 2 outlines the testing strategy. Then, Section 3 presents the results related to the program SRIC, for which four testing levels were defined (unit testing followed by three successive integration testing levels). First conclusions and direction for future work are proposed in Section 4. (author)

  6. Validating a two-dimensional bipolar spectrum model integrating DSM-5's mixed features specifier for Major Depressive Disorder.

    Science.gov (United States)

    Ferentinos, Panagiotis; Fountoulakis, Konstantinos N; Lewis, Cathryn M; Porichi, Evgenia; Dikeos, Dimitris; Papageorgiou, Charalambos; Douzenis, Athanassios

    2017-08-01

    The literature on DSM-5's 'Major Depressive Disorder with lifetime mixed features' (MDD-MF) is limited. This study investigated MDD-MF's potential inclusion into a bipolar spectrum. We recruited 287 patients with Bipolar I disorder (BD-I), BD-II, MDD-MF or 'MDD without lifetime mixed features' (MDD-noMF); most (N=280) were stabilized for at least one year on medication. Sixteen validators (clinical features, psychiatric family history, temperament, stabilizing treatment) were compared across groups and subjected to trend analyses. Two discriminant function analyses (DFA; primary and secondary), excluding or including, respectively, treatment-related predictors, explored latent dimensions maximizing between-group discrimination; mahalanobis distances between group 'centroids' were calculated. Eleven validators differed significantly across groups; nine varied monotonically along a bipolar diathesis gradient with significant linear trends; two peaked at MDD-MF and displayed significant quadratic trends. In the primary DFA, apart from a classic bipolarity dimension, correlating with hospitalizations, early age at onset, lifetime psychosis and lower anxious temperament scores, on which groups ranked along a bipolar propensity gradient, a second dimension was also significant, peaking at BD-II and MDD-MF (challenging the classic bipolar ranking), which correlated with lifetime psychiatric comorbidities, suicidality, lower lifetime psychosis rates, female gender, higher cyclothymic and lower depressive temperament scores; MDD-MF was equipoised amidst BD-II and MDD-noMF. After including treatment-related predictors (secondary DFA), discrimination improved overall but BD-II and MDD-MF were closest than any other pair, suggesting similar treatment patterns for these two groups at this naturalistic setting. To our knowledge, this is the first time a two-dimensional bipolar spectrum based on classic external validators is proposed, fitting the data better than a

  7. An Investigation of Non-Thesis Master's Program Geography Teacher Candidates' Attitudes towards Teaching Profession regarding Several Socio-Cultural Features

    Science.gov (United States)

    Sezer, Adem; Kara, Hasan; Pinar, Adnan

    2011-01-01

    The purpose of this study is to examine the attitudes of non-thesis master's degree program: geography teacher candidates towards teaching profession regarding several socio-cultural features. The study was conducted in different universities with 218 geography teacher candidates enrolled in the geography education non-thesis master's degree…

  8. Features of parallel processing of Russian language content using the basic characteristics of object-oriented high-level programming languages

    Directory of Open Access Journals (Sweden)

    Дмитрий Евгеньевич Кошкин

    2013-12-01

    Full Text Available The article discusses the general features which are traceable in the Russian language and high-level programming languages, and offers an approach to identify the relationship between words in a sentence and proposals within the text. A matter may be interesting in terms of automatic semantic analysis of texts and for the systems of automatic translation.

  9. Integrating Science Communication Training and Public Outreach Activities into the Juneau Icefield Research Program

    Science.gov (United States)

    Timm, K.; Kavanaugh, J. L.; Beedle, M. J.

    2012-12-01

    and challenges to integrating a science communication training program and outreach campaign into a field-based program were documented using ethnographic methods and student surveys. The results and lessons learned provide an avenue to explore the methods by which to integrate science communication training into remote, field-based, research training programs.

  10. Integrating an internet-mediated walking program into family medicine clinical practice: a pilot feasibility study

    Directory of Open Access Journals (Sweden)

    Sen Ananda

    2011-06-01

    Full Text Available Abstract Background Regular participation in physical activity can prevent many chronic health conditions. Computerized self-management programs are effective clinical tools to support patient participation in physical activity. This pilot study sought to develop and evaluate an online interface for primary care providers to refer patients to an Internet-mediated walking program called Stepping Up to Health (SUH and to monitor participant progress in the program. Methods In Phase I of the study, we recruited six pairs of physicians and medical assistants from two family practice clinics to assist with the design of a clinical interface. During Phase II, providers used the developed interface to refer patients to a six-week pilot intervention. Provider perspectives were assessed regarding the feasibility of integrating the program into routine care. Assessment tools included quantitative and qualitative data gathered from semi-structured interviews, surveys, and online usage logs. Results In Phase I, 13 providers used SUH and participated in two interviews. Providers emphasized the need for alerts flagging patients who were not doing well and the ability to review participant progress. Additionally, providers asked for summary views of data across all enrolled clinic patients as well as advertising materials for intervention recruitment. In response to this input, an interface was developed containing three pages: 1 a recruitment page, 2 a summary page, and 3 a detailed patient page. In Phase II, providers used the interface to refer 139 patients to SUH and 37 (27% enrolled in the intervention. Providers rarely used the interface to monitor enrolled patients. Barriers to regular use of the intervention included lack of integration with the medical record system, competing priorities, patient disinterest, and physician unease with exercise referrals. Intention-to-treat analyses showed that patients increased walking by an average of 1493 steps

  11. Rhesus monkeys (Macaca mulatta) remember agency information from past events and integrate this knowledge with spatial and temporal features in working memory.

    Science.gov (United States)

    Hoffman, Megan L; Beran, Michael J; Washburn, David A

    2018-01-01

    The purpose of the present study was to examine whether rhesus monkeys remember information about their own agency-along with spatial, temporal and contextual properties-from a previously experienced event. In Experiment 1, rhesus monkeys (n = 4) used symbols to reliably indicate whether they had performed or observed an event on a computer screen. In Experiment 2, naïve and experienced monkeys (n = 8) reported agency information when stringent controls for perceptual and proprioceptive cues were included. In Experiment 3, five of the monkeys completed a task in which they reported agency information along with spatial and temporal features of events. Two monkeys performed this agency discrimination when they could not anticipate which memory test they would receive. There was also evidence that these features were integrated in memory. Implications of this research are discussed in relation to working memory, episodic memory and self-awareness in nonhuman animals.

  12. Features of spatial and functional segregation and integration of the primate connectome revealed by trade-off between wiring cost and efficiency

    Science.gov (United States)

    Chen, Yuhan; Wang, Shengjun

    2017-01-01

    The primate connectome, possessing a characteristic global topology and specific regional connectivity profiles, is well organized to support both segregated and integrated brain function. However, the organization mechanisms shaping the characteristic connectivity and its relationship to functional requirements remain unclear. The primate brain connectome is shaped by metabolic economy as well as functional values. Here, we explored the influence of two competing factors and additional advanced functional requirements on the primate connectome employing an optimal trade-off model between neural wiring cost and the representative functional requirement of processing efficiency. Moreover, we compared this model with a generative model combining spatial distance and topological similarity, with the objective of statistically reproducing multiple topological features of the network. The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56%) explained by the generative model. While not explicitly aimed for, the trade-off model captured several key topological features of the real connectome as the generative model, yet better explained the connectivity of most regions. The majority of the remaining 33% of connections unexplained by the best trade-off model were long-distance links, which are concentrated on few cortical areas, termed long-distance connectors (LDCs). The LDCs are mainly non-hubs, but form a densely connected group overlapping on spatially segregated functional modalities. LDCs are crucial for both functional segregation and integration across different scales. These organization features revealed by the optimization analysis provide evidence that the demands of advanced functional segregation and integration among spatially distributed regions may

  13. Features of spatial and functional segregation and integration of the primate connectome revealed by trade-off between wiring cost and efficiency.

    Directory of Open Access Journals (Sweden)

    Yuhan Chen

    2017-09-01

    Full Text Available The primate connectome, possessing a characteristic global topology and specific regional connectivity profiles, is well organized to support both segregated and integrated brain function. However, the organization mechanisms shaping the characteristic connectivity and its relationship to functional requirements remain unclear. The primate brain connectome is shaped by metabolic economy as well as functional values. Here, we explored the influence of two competing factors and additional advanced functional requirements on the primate connectome employing an optimal trade-off model between neural wiring cost and the representative functional requirement of processing efficiency. Moreover, we compared this model with a generative model combining spatial distance and topological similarity, with the objective of statistically reproducing multiple topological features of the network. The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56% explained by the generative model. While not explicitly aimed for, the trade-off model captured several key topological features of the real connectome as the generative model, yet better explained the connectivity of most regions. The majority of the remaining 33% of connections unexplained by the best trade-off model were long-distance links, which are concentrated on few cortical areas, termed long-distance connectors (LDCs. The LDCs are mainly non-hubs, but form a densely connected group overlapping on spatially segregated functional modalities. LDCs are crucial for both functional segregation and integration across different scales. These organization features revealed by the optimization analysis provide evidence that the demands of advanced functional segregation and integration among spatially

  14. KOC's integrity management program for non-piggable pipelines, a case study

    Energy Technology Data Exchange (ETDEWEB)

    Khera, Ashish [Allied Engineers, New Delhi (India)], email: akhera@alliedengineer.com; Al-Mithin, Abdul Wahab; Safri, Shabbir T.; Al-Sulaiman, Saleh [Kuwait Oil Company, Ahmadi (Kuwait)], email: amithin@kockw.com, email: ssafri@kockw.com, email: ssulaima@kockw.com; Marr, James E. [TransCanada Pipeline Ltd., Calgary, AB (Canada)], email: jim_marr@transcanada.com

    2010-07-01

    The Kuwait Oil Company (KOC) has a network consisting of 420 transmission pipelines. It realized that current integrity management techniques could not all be applied to each pipeline in its system. After completing a risk assessment analysis, KOC separated the pipelines into two categories, namely piggable and non-piggable lines. This paper deals with risk analysis for non-piggable pipelines, which represent more than 60% of the system. The External Corrosion Direct Assessment (ECDA) process is iterative and includes four steps: integration of data from available line histories; multiple indirect field surveys; direct examination; post-assessment of the documented results. Some measures are recommended as a result of this case study; for example, the ECDA program should be implemented on a per-line basis; pipelines should be further subdivided into unique ECDA regions; customized or innovative techniques should be implemented for each ECDA region.

  15. An object-oriented programming system for the integration of internet-based bioinformatics resources.

    Science.gov (United States)

    Beveridge, Allan

    2006-01-01

    The Internet consists of a vast inhomogeneous reservoir of data. Developing software that can integrate a wide variety of different data sources is a major challenge that must be addressed for the realisation of the full potential of the Internet as a scientific research tool. This article presents a semi-automated object-oriented programming system for integrating web-based resources. We demonstrate that the current Internet standards (HTML, CGI [common gateway interface], Java, etc.) can be exploited to develop a data retrieval system that scans existing web interfaces and then uses a set of rules to generate new Java code that can automatically retrieve data from the Web. The validity of the software has been demonstrated by testing it on several biological databases. We also examine the current limitations of the Internet and discuss the need for the development of universal standards for web-based data.

  16. Archive of Core and Site/Hole Data and Photographs from the Integrated Ocean Drilling Program (IODP)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The US Science Operator for the Integrated Ocean Drilling Program (IODP) operated the drilling vessel JOIDES Resolution from 2004-2013 for worldwide expeditions...

  17. Integrating interdisciplinary pain management into primary care: development and implementation of a novel clinical program.

    Science.gov (United States)

    Dorflinger, Lindsey M; Ruser, Christopher; Sellinger, John; Edens, Ellen L; Kerns, Robert D; Becker, William C

    2014-12-01

    The aims of this study were to develop and implement an interdisciplinary pain program integrated in primary care to address stakeholder-identified gaps. Program development and evaluation project utilizing a Plan-Do-Study-Act (PDSA) approach to address the identified problem of insufficient pain management resources within primary care. A large Healthcare System within the Veterans Health Administration, consisting of two academically affiliated medical centers and six community-based outpatients clinics. An interprofessional group of stakeholders participated in a Rapid Process Improvement Workshop (RPIW), a consensus-building process to identify systems-level gaps and feasible solutions and obtain buy-in. Changes were implemented in 2012, and in a 1-year follow-up, we examined indicators of engagement in specialty and multimodal pain care services as well as patient and provider satisfaction. In response to identified barriers, RPIW participants proposed and outlined two readily implementable, interdisciplinary clinics embedded within primary care: 1) the Integrated Pain Clinic, providing in-depth assessment and triage to targeted resources; and 2) the Opioid Reassessment Clinic, providing assessment and structured monitoring of patients with evidence of safety, efficacy, or misuse problems with opioids. Implementation of these programs led to higher rates of engagement in specialty and multimodal pain care services; patients and providers reported satisfaction with these services. Our PDSA cycle engaged an interprofessional group of stakeholders that recommended introduction of new systems-based interventions to better integrate pain resources into primary care to address reported barriers. Early data suggest improved outcomes; examination of additional outcomes is planned. Wiley Periodicals, Inc.

  18. Towards the integration of mental practice in rehabilitation programs. A critical review

    Directory of Open Access Journals (Sweden)

    Francine eMalouin

    2013-09-01

    Full Text Available Many clinical studies have investigated the use of mental practice (MP through motor imagery (MI to enhance functional recovery of patients with diverse physical disabilities. Although beneficial effects have been generally reported for training motor functions in persons with chronic stroke (e.g. reaching, writing, walking, attempts to integrate MP within rehabilitation programs have been met with mitigated results. These findings have stirred further questioning about the value of MP in neurological rehabilitation. In fact, despite abundant systematic reviews, which customarily focused on the methodological merits of selected studies, several questions about factors underlying observed effects remain to be addressed. This review discusses these issues in an attempt to identify factors likely to hamper the integration of MP within rehabilitation programs. First, the rationale underlying the use of MP for training motor function is briefly reviewed. Second, three modes of MI delivery are proposed based on the analysis of the research protocols from 27 studies in persons with stroke and Parkinson’s disease. Third, for each mode of MI delivery, a general description of MI training is provided. Fourth, the review discusses factors influencing MI training outcomes such as: the adherence to MI training, the amount of training and the interaction between physical and mental rehearsal; the use of relaxation, the selection of reliable, valid and sensitive outcome measures, the heterogeneity of the patient groups, the selection of patients and the mental rehearsal procedures. To conclude, the review proposes a framework for integrating MP in rehabilitation programs and suggests research targets for steering the implementation of MP in the early stages of the rehabilitation process. The challenge has now shifted towards the demonstration that MI training can enhance the effects of regular therapy in persons with subacute stroke during the period of

  19. High-Resolution Studies of Oceanic Spreading Center Volcanic and Hydrothermal Features and Processes - New Insights from Ridge 2000 Program Experiments

    Science.gov (United States)

    Fornari, D. J.

    2011-12-01

    During the past 60 years of research on mid-ocean ridges (MORs) we have exponentially increased our understandings one of the planet's most fundamental features and the myriad processes associated with the transfer of energy from the mantle to the hydrosphere that is focused along accretionary plate boundaries. The past decade's research, implemented by a broad community of scientists in numerous disciplines has yielded a watershed of information that has helped to make both temporal and spatial connections between processes that store and deliver magma to the crust and seafloor, and the consequent hydrothermal and biological phenomena that derive from that energy transfer. Ridge 2000 Program research at each of the three Integrated Study Sites (ISSs) - East Pacific Rise 8-10N, Juan de Fuca - Endeavour Segment, and Eastern Lau Spreading Center - provided an opportunity to coordinate field experiments, laboratory studies and modeling that has lead to new concepts of oceanic spreading center processes. In particular, the latest generation of near-bottom seafloor mapping and sampling systems and a new array of deep submergence vehicles, which include remotely operated vehicles (ROVs) and autonomous underwater vehicles (AUVs), as well more traditional human occupied vehicles (HOVs) like Alvin, have yielded important new views of MOR seafloor. These systems have allowed us to resolve the sub-meter topography of specific volcanic and hydrothermal features and relate them to distributions of hydrothermal communities, chemical variations among hydrothermal chimneys and their fluid effluent, and to axial structures that are surface manifestations of tectonic processes. In situ chemical, biological and microbial studies carried out during the past decade have increasingly shown how tightly linked chemical and biological processes are within MOR hydrothermal communities. Previous hypotheses concerning frequency of magmatism and volcanic eruptions that have related

  20. The VIS-AD data model: Integrating metadata and polymorphic display with a scientific programming language

    Science.gov (United States)

    Hibbard, William L.; Dyer, Charles R.; Paul, Brian E.

    1994-01-01

    The VIS-AD data model integrates metadata about the precision of values, including missing data indicators and the way that arrays sample continuous functions, with the data objects of a scientific programming language. The data objects of this data model form a lattice, ordered by the precision with which they approximate mathematical objects. We define a similar lattice of displays and study visualization processes as functions from data lattices to display lattices. Such functions can be applied to visualize data objects of all data types and are thus polymorphic.

  1. Integrated Data Collection Analysis (IDCA) Program - RDX Standard Data Set 2

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Phillips, Jason J. [Air Force Research Lab. (AFRL), Tyndall Air Force Base, FL (United States); Shelley, Timothy J. [Applied Research Associates, Tyndall Air Force Base, FL (United States); Reyes, Jose A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-02-20

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of the RDX Type II Class 5 standard, from testing the second time in the Proficiency Test. This RDX testing (Set 2) compared to the first (Set 1) was found to have about the same impact sensitivity, have more BAM friction sensitivity, less ABL friction sensitivity, similar ESD sensitivity, and same DSC sensitivity.

  2. Preventive Dental Care: An Educational Program to Integrate Oral Care Into Pediatric Oncology
.

    Science.gov (United States)

    Hartnett, Erin; Krainovich-Miller, Barbara

    2017-10-01

    Early childhood dental caries (dental cavities) is an infectious process. The development of oral problems during cancer care results in pain, fever, and delay in treatment. 
. The objective of this project was to integrate preventive oral care into pediatric oncology care. 
. This project consisted of an educational program for pediatric oncology providers who completed pre- and postprogram surveys assessing oral health knowledge, attitudes, and practice; attended an oral health education session; and performed oral assessment and fluoride varnish application on children during cancer treatment. 
. Three major outcomes resulted from this project.

  3. Integrated Data Collection Analysis (IDCA) Program — Bullseye® Smokeless Powder

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Phillips, Jason J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shelley, Timothy J. [Bureau of Alcohol, Tobacco and Firearms, Redstone Arsenal, AL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-05-30

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of Bullseye® smokeless powder (Gunpowder). The participants found the Gunpowder: 1) to have a range of sensitivity to impact, from less than RDX to almost as sensitive as PETN, 2) to be moderately sensitive to BAM and ABL friction, 3) have a range for ESD, from insensitive to more sensitive than PETN, and 4) to have thermal sensitivity about the same as PETN and RDX.

  4. Effects of an Integrated Stress Management Program (ISMP) for Psychologically Distressed Students: A Randomized Controlled Trial.

    Science.gov (United States)

    Kim, Sunah; Lee, Hyangkyu; Kim, Hyunlye; Noh, Dabok; Lee, Hyunhwa

    2016-07-01

    This study aimed to evaluate the effects of an integrated stress management program (ISMP) on college life stress, stress coping, psychological distress, and cortisol among male college students. Out of 137 initially enrolled students, 99 participants were identified as distressed subjects and randomly assigned to either the ISMP or control group. Ultimately, 84 participants (43: experimental, 41: control) completed pretest-posttest. The experimental group received eight 2-hr sessions over 4 weeks. Stress and psychological distress decreased significantly, whereas stress coping and cortisol did not improve significantly. Further studies with longer follow-up periods and physiological interventions are required. © 2015 Wiley Periodicals, Inc.

  5. Monitoring of persistent accreting pulsating neutron stars observed during the INTEGRAL Core Program

    DEFF Research Database (Denmark)

    Sidoli, L.; Wilms, J.; Paizis, A.

    2004-01-01

    The INTEGRAL satellite is performing regular scans of the Galactic plane (CPS) every 12 days together with a deep exposure of the Galactic Center region (GCDE). Our collaboration is processing the data from this survey on a regular basis in order to monitor the evolution of the spectral and timin...... properties of the pulsating persistent neutron star sources observed. We present here an overview over the whole monitoring program and the status of the project and we report on the preliminary results of the analysis of the few scans already performed....

  6. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Quality Assurance Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; R. Nims; K. J. Kvarfordt; C. Wharton

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment using a personal computer running the Microsoft Windows operating system. SAPHIRE is primarily funded by the U.S. Nuclear Regulatory Commission (NRC). The role of the INL in this project is that of software developer and tester. This development takes place using formal software development procedures and is subject to quality assurance (QA) processes. The purpose of this document is to describe how the SAPHIRE software QA is performed for Version 6 and 7, what constitutes its parts, and limitations of those processes.

  7. Effect of an Integrated Health Management Program Based on Successful Aging in Korean Women.

    Science.gov (United States)

    Ahn, Okhee; Cha, Hye Gyeong; Chang, Soo Jung; Cho, Hyun-Choul; Kim, Hee Sun

    2015-01-01

    This study evaluates the efficacy of an integrated health management program (IHMP) based on successful aging in older women. A single group pretest and posttest research design was employed, with a sample of 33 older Korean women over 60 years registered in a public health center. The intervention, including exercise, health education, and social activities, was performed 3 hr per week for 12 weeks. Demographic characteristics, body composition, physical fitness, biomarkers, depression, and social support were measured. Data were analyzed with a Wilcoxon signed-rank test, statistical significance levels were set at p successful aging in older Korean women. © 2014 Wiley Periodicals, Inc.

  8. A cost effectiveness study of integrated care in health services delivery: a diabetes program in Australia

    Directory of Open Access Journals (Sweden)

    Snow Jill

    2008-10-01

    Full Text Available Abstract Background Type 2 diabetes is rapidly growing as a proportion of the disease burden in Australia as elsewhere. This study addresses the cost effectiveness of an integrated approach to assisting general practitioners (GPs with diabetes management. This approach uses a centralized database of clinical data of an Australian Division of General Practice (a network of GPs to co-ordinate care according to national guidelines. Methods Long term outcomes for patients in the program were derived using clinical parameters after 5 years of program participation, and the United Kingdom Prospective Diabetes Study (UKPDS Outcomes Model, to project outcomes for 40 years from the time of diagnosis and from 5 years post-diagnosis. Cost information was obtained from a range of sources. While program costs are directly available, and costs of complications can be estimated from the UKPDS model, other costs are estimated by comparing costs in the Division with average costs across the state or the nation. The outcome and cost measures are used derive incremental cost-effectiveness ratios. Results The clinical data show that the program is effective in the short term, with improvement or no statistical difference in most clinical measures over 5 years. Average HbA1c levels increased by less than expected over the 5 year period. While the program is estimated to generate treatment cost savings, overall net costs are positive. However, the program led to projected improvements in expected life years and Quality Adjusted Life Expectancy (QALE, with incremental cost effectiveness ratios of $A8,106 per life-year saved and $A9,730 per year of QALE gained. Conclusions The combination of an established model of diabetes progression and generally available data has provided an opportunity to establish robust methods of testing the cost effectiveness of a program for which a formal control group was not available. Based on this methodology, integrated health care

  9. Education, outreach, and inclusive engagement: Towards integrated indicators of successful program outcomes in participatory science.

    Science.gov (United States)

    Haywood, Benjamin K; Besley, John C

    2014-01-01

    The use and utility of science in society is often influenced by the structure, legitimacy, and efficacy of the scientific research process. Public participation in scientific research (PPSR) is a growing field of practice aimed at enhancing both public knowledge and understanding of science (education outreach) and the efficacy and responsiveness of scientific research, practice, and policy (participatory engagement). However, PPSR objectives focused on "education outreach" and "participatory engagement" have each emerged from diverse theoretical traditions that maintain distinct indicators of success used for program development and evaluation. Although areas of intersection and overlap among these two traditions exist in theory and practice, a set of comprehensive standards has yet to coalesce that supports the key principles of both traditions in an assimilated fashion. To fill this void, a comprehensive indicators framework is proposed with the goal of promoting a more integrative and synergistic PPSR program development and assessment process.

  10. DOE In Situ Remediation Integrated Program. In situ manipulation technologies subprogram plan

    Energy Technology Data Exchange (ETDEWEB)

    Yow, J.L. Jr.

    1993-12-22

    The In Situ Remediation Integrated Program (ISRP) supports and manages a balanced portfolio of applied research and development activities in support of DOE environmental restoration and waste management needs. ISRP technologies are being developed in four areas: containment, chemical and physical treatment, in situ bioremediation, and in situ manipulation (including electrokinetics). the focus of containment is to provide mechanisms to stop contaminant migration through the subsurface. In situ bioremediation and chemical and physical treatment both aim to destroy or eliminate contaminants in groundwater and soils. In situ manipulation (ISM) provides mechanisms to access contaminants or introduce treatment agents into the soil, and includes other technologies necessary to support the implementation of ISR methods. Descriptions of each major program area are provided to set the technical context of the ISM subprogram. Typical ISM needs for major areas of in situ remediation research and development are identified.

  11. Integrated Status and Effectiveness Monitoring Program - Entiat River Snorkel Surveys and Rotary Screw Trap, 2007.

    Energy Technology Data Exchange (ETDEWEB)

    Nelle, R.D.

    2008-01-01

    The USFWS Mid-Columbia River Fishery Resource Office conducted snorkel surveys at 24 sites during the summer and fall periods of 2006 survey periods as part of the Integrated Status and Effectiveness Monitoring Program in the Entiat River. A total of 37,938 fish from 15 species/genera and an unknown category were enumerated. Chinook salmon were the overall most common fish observed and comprised 15% of fish enumerated followed by rainbow trout (10%) and mountain whitefish (7%). Day surveys were conducted during the summer period 2007 (August), while night surveys were conducted during the fall 2007 (October) surveys. The USFWS Mid-Columbia River Fishery Resource Office (MCFRO) operated two rotary screw traps on the Entiat River as part of the Integrated Status and Effectiveness Monitoring Program (ISEMP) program from August through November of 2007. Along with the smolt traps, juvenile emigrants were also captured at remote locations throughout the Entiat watershed and its major tributary, the Mad River. A total of 999 wild Oncorhynchus mykiss and 5,107 wild run O. tshawytscha were PIT tagged during the study period. Rotary screw trap efficiencies averaged 22.3% for juvenile O. tshawytscha and 9.0% for juvenile O. mykiss. Rotary screw traps operated 7 days a week and remote capture operations were conducted when flow and temperature regimes permitted. This is third annual progress report to Bonneville Power Administration for the snorkel surveys conducted in the Entiat River as related to long-term effectiveness monitoring of restoration programs in this watershed. The objective of this study is to monitor the fish habitat utilization of planned in-stream restoration efforts in the Entiat River by conducting pre- and post-construction snorkel surveys at selected treatment and control sites.

  12. Integration

    DEFF Research Database (Denmark)

    Emerek, Ruth

    2004-01-01

    Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration......Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration...

  13. Health informatics and analytics - building a program to integrate business analytics across clinical and administrative disciplines.

    Science.gov (United States)

    Tremblay, Monica Chiarini; Deckard, Gloria J; Klein, Richard

    2016-07-01

    Health care organizations must develop integrated health information systems to respond to the numerous government mandates driving the movement toward reimbursement models emphasizing value-based and accountable care. Success in this transition requires integrated data analytics, supported by the combination of health informatics, interoperability, business process design, and advanced decision support tools. This case study presents the development of a master's level cross- and multidisciplinary informatics program offered through a business school. The program provides students from diverse backgrounds with the knowledge, leadership, and practical application skills of health informatics, information systems, and data analytics that bridge the interests of clinical and nonclinical professionals. This case presents the actions taken and challenges encountered in navigating intra-university politics, specifying curriculum, recruiting the requisite interdisciplinary faculty, innovating the educational format, managing students with diverse educational and professional backgrounds, and balancing multiple accreditation agencies. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. Integrating between Malay culture and conservation in Green campus program: Best practices from Universitas Riau, Indonesia

    Science.gov (United States)

    Suwondo, Darmadi, Yunus, Mohd.

    2017-11-01

    Green campus program (GCP) is a policy to optimize the role of the University of Riau in implementing sustainable development. Green campus development is done by integrating Malay culture and conservation in every implementation of the program. We identify the biophysical, economic and socio-cultural characteristics as well as the problems encountered in the campus environment. This study uses desk study, survey, and focus group discussion (FGD). GCP analysis is divided into several stages, namely assess problem, design, implementation, monitor, evaluate and adjust. Bina Widya Campus of Universitas Riau has a good biodiversity of flora and fauna with species characteristics in lowland tropical forest ecosystems. Plant species of the Dipterocarpaceae family are the dominant species, whereas fauna is from reptile, leaves, and mammals. Efforts to maintain and enhance species diversity are undertaken by designing and constructing Arboretum and Ecoedupark for the ex situ conservation of flora and fauna. The enrichment of species is carried out by planting vegetation types that are closely related to Malay culture. On the other hand, the management of the green campus faces challenges in the diverse perceptions of stakeholders with low levels of academic participation. Economically the existence of the campus provides a multiplier effect on the emergence of various economic activities of the community around the campus. Implementation of green university campus of Riau University by integrating Melayu culture and conservation contributes to the creation of green open space which is increasingly widespread and able to support sustainable development, especially in Pekanbaru City.

  15. SAMPLE RESULTS FROM THE INTEGRATED SALT DISPOSITION PROGRAM MACROBATCH 4 TANK 21H QUALIFICATION SAMPLES

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T.; Fink, S.

    2011-06-22

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H to qualify them for use in the Integrated Salt Disposition Program (ISDP) Batch 4 processing. All sample results agree with expectations based on prior analyses where available. No issues with the projected Salt Batch 4 strategy are identified. This revision includes additional data points that were not available in the original issue of the document, such as additional plutonium results, the results of the monosodium titanate (MST) sorption test and the extraction, scrub strip (ESS) test. This report covers the revision to the Tank 21H qualification sample results for Macrobatch (Salt Batch) 4 of the Integrated Salt Disposition Program (ISDP). A previous document covers initial characterization which includes results for a number of non-radiological analytes. These results were used to perform aluminum solubility modeling to determine the hydroxide needs for Salt Batch 4 to prevent the precipitation of solids. Sodium hydroxide was then added to Tank 21 and additional samples were pulled for the analyses discussed in this report. This work was specified by Task Technical Request and by Task Technical and Quality Assurance Plan (TTQAP).

  16. Establishing an Integrative Medicine Program Within an Academic Health Center: Essential Considerations.

    Science.gov (United States)

    Eisenberg, David M; Kaptchuk, Ted J; Post, Diana E; Hrbek, Andrea L; O'Connor, Bonnie B; Osypiuk, Kamila; Wayne, Peter M; Buring, Julie E; Levy, Donald B

    2016-09-01

    Integrative medicine (IM) refers to the combination of conventional and "complementary" medical services (e.g., chiropractic, acupuncture, massage, mindfulness training). More than half of all medical schools in the United States and Canada have programs in IM, and more than 30 academic health centers currently deliver multidisciplinary IM care. What remains unclear, however, is the ideal delivery model (or models) whereby individuals can responsibly access IM care safely, effectively, and reproducibly in a coordinated and cost-effective way.Current models of IM across existing clinical centers vary tremendously in their organizational settings, principal clinical focus, and services provided; practitioner team composition and training; incorporation of research activities and educational programs; and administrative organization (e.g., reporting structure, use of medical records, scope of clinical practice) and financial strategies (i.e., specific business plans and models for sustainability).In this article, the authors address these important strategic issues by sharing lessons learned from the design and implementation of an IM facility within an academic teaching hospital, the Brigham and Women's Hospital at Harvard Medical School; and review alternative options based on information about IM centers across the United States.The authors conclude that there is currently no consensus as to how integrative care models should be optimally organized, implemented, replicated, assessed, and funded. The time may be right for prospective research in "best practices" across emerging models of IM care nationally in an effort to standardize, refine, and replicate them in preparation for rigorous cost-effectiveness evaluations.

  17. An integrated malaria control program with community participation on the Pacific Coast of Colombia

    Directory of Open Access Journals (Sweden)

    William Rojas

    Full Text Available The study focuses on integrated malaria control in 23 communities on the Pacific Coast of Colombia, with several elements of an ecosystem approach to human health, including malaria-related sociopolitical, ecological, and economic factors. The program fostered community participation. The program presented here had 2 components: implementation and research. The first was conducted in 23 communities, 21 of which lacked adequate health services in terms of education, community participation, prompt diagnosis and complete treatment, and vector control. Research focused on specific vector control measures and the current national health services decentralization process. The project: 1 created a malaria prevention culture in the community; 2 avoided deaths from malaria (no fatal cases in the 3-year period, compared to 5-8 deaths a year previously; 3 avoided cases of cerebral malaria (no cases, as compared to 90-110 per year previously; 4 reduced malaria incidence by 45.36%; 5 decreased length of sick leave from 7.52 to 3.7 days; 6 established a permanent network of microscope technicians and 2-way radio communications; 7 integrated work by local, regional, and outside institutions; 8 demonstrated efficacy of insecticide-impregnated bednets to reduce malaria transmission.

  18. An integrated malaria control program with community participation on the Pacific Coast of Colombia

    Directory of Open Access Journals (Sweden)

    Rojas William

    2001-01-01

    Full Text Available The study focuses on integrated malaria control in 23 communities on the Pacific Coast of Colombia, with several elements of an ecosystem approach to human health, including malaria-related sociopolitical, ecological, and economic factors. The program fostered community participation. The program presented here had 2 components: implementation and research. The first was conducted in 23 communities, 21 of which lacked adequate health services in terms of education, community participation, prompt diagnosis and complete treatment, and vector control. Research focused on specific vector control measures and the current national health services decentralization process. The project: 1 created a malaria prevention culture in the community; 2 avoided deaths from malaria (no fatal cases in the 3-year period, compared to 5-8 deaths a year previously; 3 avoided cases of cerebral malaria (no cases, as compared to 90-110 per year previously; 4 reduced malaria incidence by 45.36%; 5 decreased length of sick leave from 7.52 to 3.7 days; 6 established a permanent network of microscope technicians and 2-way radio communications; 7 integrated work by local, regional, and outside institutions; 8 demonstrated efficacy of insecticide-impregnated bednets to reduce malaria transmission.

  19. Education and leisure: analyzing the Integrated School Program in Belo Horizonte

    Directory of Open Access Journals (Sweden)

    Marcília de Sousa Silva

    2015-01-01

    Full Text Available This article aims to analyze the concepts of leisure and education that permeate the documents in the Integrated School Program in Belo Horizonte. The analysis was based on the Policy cycle approach and emphasized the contexts of influence and the policy text production. Thus, the formation of the political agenda, the Political Pedagogical Project Program and the Strategic Plan 2010-2030 BH were investigated. The policy context is not organized in a linear fashion; it is a process of groups of interest interaction. With the discourse of coping with school failure, revealed by the students’ yield and flow evaluation indices (approval, repetition and dropout, the Integrated School education documents announce education and leisure as forms of production, strengthening links between public and private. The right to education is restricted to children’s and youth’s access and permanence in school without creating a perspective of universalization and quality. The documents address the leisure with a simplistic view of construction and maintenance of equipment and the idea of activity

  20. Real-world program evaluation of integrated behavioral health care: Improving scientific rigor.

    Science.gov (United States)

    Funderburk, Jennifer S; Shepardson, Robyn L

    2017-06-01

    Designing systematic, scientifically rigorous program evaluations (PE) is 1 way to contribute to the significant need to build best practices and a stronger evidence base for integrated behavioral health care. However, there are many potential pitfalls when conducting PE in real-world settings, and many clinicians and administrators may be hesitant to engage in PE due to lack of training or resources. Rigorous PE can be achieved feasibly and efficiently. This article discusses common challenges that arise when conducting PE in integrated behavioral health care settings and illustrates ways to increase the methodological quality of PE efforts using lessons learned from 2 real-world case examples. The first example included a PE of a training program for brief alcohol interventions, and the second example included a PE of a depression medication monitoring service. The case examples demonstrate the need for strategic planning beforehand, including the use of a conceptual framework as well as appropriate study designs/methodology, measurement, and the need for consistency to achieve a well-designed PE. Using the recommendations within this article, it is hoped that the quality of PEs can be improved resulting in more generalizable data that can be used to inform organizations and policymakers to improve health care delivery. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Botswana water and surface energy balance research program. Part 1: Integrated approach and field campaign results

    Science.gov (United States)

    Vandegriend, A. A.; Owe, M.; Vugts, H. F.; Ramothwa, G. K.

    1992-01-01

    The Botswana water and surface energy balance research program was developed to study and evaluate the integrated use of multispectral satellite remote sensing for monitoring the hydrological status of the Earth's surface. Results of the first part of the program (Botswana 1) which ran from 1 Jan. 1988 - 31 Dec. 1990 are summarized. Botswana 1 consisted of two major, mutually related components: a surface energy balance modeling component, built around an extensive field campaign; and a passive microwave research component which consisted of a retrospective study of large scale moisture conditions and Nimbus scanning multichannel microwave radiometer microwave signatures. The integrated approach of both components in general are described and activities performed during the surface energy modeling component including the extensive field campaign are summarized. The results of the passive microwave component are summarized. The key of the field campaign was a multilevel approach, whereby measurements by various similar sensors were made at several altitudes and resolution. Data collection was performed at two adjacent sites of contrasting surface character. The following measurements were made: micrometeorological measurements, surface temperatures, soil temperatures, soil moisture, vegetation (leaf area index and biomass), satellite data, aircraft data, atmospheric soundings, stomatal resistance, and surface emissivity.

  2. Integrated programs for mothers with substance abuse issues: A systematic review of studies reporting on parenting outcomes.

    Science.gov (United States)

    Niccols, Alison; Milligan, Karen; Sword, Wendy; Thabane, Lehana; Henderson, Joanna; Smith, Ainsley

    2012-03-19

    Integrated treatment programs (those that include on-site pregnancy-, parenting-, or child-related services with addiction services) were developed to break the intergenerational cycle of addiction, dysfunctional parenting, and poor outcomes for mothers and children, yet there has been no systematic review of studies of parenting outcomes. As part of larger systematic review to examine the effectiveness of integrated programs for mothers with substance abuse issues, we performed a systematic review of studies published from 1990 to 2011 with data on parenting outcomes. Literature search strategies included online bibliographic database searches, checking printed sources, and requests to researchers. Studies were included if all participants were mothers with substance abuse problems at baseline, the treatment program included at least one specific substance use treatment and at least one parenting or child service, and there were quantitative data on parenting outcomes. We summarized data on parenting skills and capacity outcomes. There were 24 cohort studies, 3 quasi-experimental studies, and 4 randomized trials. In the three randomized trials comparing integrated programs to addiction treatment-as-usual (N = 419), most improvements in parenting skills favored integrated programs and most effect sizes indicated that this advantage was small, ds = -0.02 to 0.94. Results for child protection services involvement did not differ by group. In the three studies that examined factors associated with treatment effects, parenting improvements were associated with attachment-based parenting interventions, children residing in the treatment facility, and improvements in maternal mental health. This is the first systematic review of studies evaluating the effectiveness of integrated programs on parenting. The limited available evidence supports integrated programs, as findings suggest that they are associated with improvements in parenting skills. However, more research is

  3. Evaluation of NSF's Program of Grants and Vertical Integration of Research and Education in the Mathematical Sciences (VIGRE)

    Science.gov (United States)

    National Academies Press, 2009

    2009-01-01

    In 1998, the National Science Foundation (NSF) launched a program of Grants for Vertical Integration of Research and Education in the Mathematical Sciences (VIGRE). These grants were designed for institutions with PhD-granting departments in the mathematical sciences, for the purpose of developing high-quality education programs, at all levels,…

  4. BEfree: A new psychological program for binge eating that integrates psychoeducation, mindfulness, and compassion.

    Science.gov (United States)

    Pinto-Gouveia, José; Carvalho, Sérgio A; Palmeira, Lara; Castilho, Paula; Duarte, Cristiana; Ferreira, Cláudia; Duarte, Joana; Cunha, Marina; Matos, Marcela; Costa, Joana

    2017-09-01

    Binge eating disorder (BED) is associated with several psychological and medical problems, such as obesity. Approximately 30% of individuals seeking weight loss treatments present binge eating symptomatology. Moreover, current treatments for BED lack efficacy at follow-up assessments. Developing mindfulness and self-compassion seem to be beneficial in treating BED, although there is still room for improvement, which may include integrating these different but complimentary approaches. BEfree is the first program integrating psychoeducation-, mindfulness-, and compassion-based components for treating women with binge eating and obesity. To test the acceptability and efficacy up to 6-month postintervention of a psychological program based on psychoeducation, mindfulness, and self-compassion for obese or overweight women with BED. A controlled longitudinal design was followed in order to compare results between BEfree (n = 19) and waiting list group (WL; n = 17) from preintervention to postintervention. Results from BEfree were compared from preintervention to 3- and 6-month follow-up. BEfree was effective in eliminating BED; in diminishing eating psychopathology, depression, shame and self-criticism, body-image psychological inflexibility, and body-image cognitive fusion; and in improving obesity-related quality of life and self-compassion when compared to a WL control group. Results were maintained at 3- and 6-month follow-up. Finally, participants rated BEfree helpful for dealing with impulses and negative internal experiences. These results seem to suggest the efficacy of BEfree and the benefit of integrating different components such as psychoeducation, mindfulness, and self-compassion when treating BED in obese or overweight women. The current study provides evidence of the acceptability of a psychoeducation, mindfulness, and compassion program for binge eating in obesity (BEfree); Developing mindfulness and self-compassionate skills is an effective way of

  5. Genetic Programming and Frequent Itemset Mining to Identify Feature Selection Patterns of iEEG and fMRI Epilepsy Data.

    Science.gov (United States)

    Smart, Otis; Burrell, Lauren

    2015-03-01

    Pattern classification for intracranial electroencephalogram (iEEG) and functional magnetic resonance imaging (fMRI) signals has furthered epilepsy research toward understanding the origin of epileptic seizures and localizing dysfunctional brain tissue for treatment. Prior research has demonstrated that implicitly selecting features with a genetic programming (GP) algorithm more effectively determined the proper features to discern biomarker and non-biomarker interictal iEEG and fMRI activity than conventional feature selection approaches. However for each the iEEG and fMRI modalities, it is still uncertain whether the stochastic properties of indirect feature selection with a GP yield (a) consistent results within a patient data set and (b) features that are specific or universal across multiple patient data sets. We examined the reproducibility of implicitly selecting features to classify interictal activity using a GP algorithm by performing several selection trials and subsequent frequent itemset mining (FIM) for separate iEEG and fMRI epilepsy patient data. We observed within-subject consistency and across-subject variability with some small similarity for selected features, indicating a clear need for patient-specific features and possible need for patient-specific feature selection or/and classification. For the fMRI, using nearest-neighbor classification and 30 GP generations, we obtained over 60% median sensitivity and over 60% median selectivity. For the iEEG, using nearest-neighbor classification and 30 GP generations, we obtained over 65% median sensitivity and over 65% median selectivity except one patient.

  6. Integrative Curriculum Development in Nuclear Education and Research Vertical Enhancement Program

    Energy Technology Data Exchange (ETDEWEB)

    Egarievwe, Stephen U.; Jow, Julius O.; Edwards, Matthew E.; Montgomery, V. Trent [Nuclear Engineering and Radiological Science Center, Alabama A and M University, Huntsville, AL (United States); James, Ralph B.; Blackburn, Noel D. [Nonproliferation and National Security Department, Brookhaven National Laboratory, Upton, NY (United States); Glenn, Chance M. [College of Engineering, Technology and Physical Sciences, Alabama A and M University, Huntsville, AL (United States)

    2015-07-01

    Using a vertical education enhancement model, a Nuclear Education and Research Vertical Enhancement (NERVE) program was developed. The NERVE program is aimed at developing nuclear engineering education and research to 1) enhance skilled workforce development in disciplines relevant to nuclear power, national security and medical physics, and 2) increase the number of students and faculty from underrepresented groups (women and minorities) in fields related to the nuclear industry. The program uses multi-track training activities that vertically cut across the several education domains: undergraduate degree programs, graduate schools, and post-doctoral training. In this paper, we present the results of an integrative curriculum development in the NERVE program. The curriculum development began with nuclear content infusion into existing science, engineering and technology courses. The second step involved the development of nuclear engineering courses: 1) Introduction to Nuclear Engineering, 2) Nuclear Engineering I, and 2) Nuclear Engineering II. The third step is the establishment of nuclear engineering concentrations in two engineering degree programs: 1) electrical engineering, and 2) mechanical engineering. A major outcome of the NERVE program is a collaborative infrastructure that uses laboratory work, internships at nuclear facilities, on-campus research, and mentoring in collaboration with industry and government partners to provide hands-on training for students. The major activities of the research and education collaborations include: - One-week spring training workshop at Brookhaven National Laboratory: The one-week training and workshop is used to enhance research collaborations and train faculty and students on user facilities/equipment at Brookhaven National Laboratory, and for summer research internships. Participants included students, faculty members at Alabama A and M University and research collaborators at BNL. The activities include 1) tour and

  7. A multi-feature integration method for fatigue crack detection and crack length estimation in riveted lap joints using Lamb waves

    Science.gov (United States)

    He, Jingjing; Guan, Xuefei; Peng, Tishun; Liu, Yongming; Saxena, Abhinav; Celaya, Jose; Goebel, Kai

    2013-10-01

    This paper presents an experimental study of damage detection and quantification in riveted lap joints. Embedded lead zirconate titanate piezoelectric (PZT) ceramic wafer-type sensors are employed to perform in situ non-destructive evaluation (NDE) during fatigue cyclical loading. PZT wafers are used to monitor the wave reflection from the boundaries of the fatigue crack at the edge of bolt joints. The group velocity of the guided wave is calculated to select a proper time window in which the received signal contains the damage information. It is found that the fatigue crack lengths are correlated with three main features of the signal, i.e., correlation coefficient, amplitude change, and phase change. It was also observed that a single feature cannot be used to quantify the damage among different specimens since a considerable variability was observed in the response from different specimens. A multi-feature integration method based on a second-order multivariate regression analysis is proposed for the prediction of fatigue crack lengths using sensor measurements. The model parameters are obtained using training datasets from five specimens. The effectiveness of the proposed methodology is demonstrated using several lap joint specimens from different manufactures and under different loading conditions.

  8. A mixed-methods evaluation of an Integrated Medication Management program and implications for implementation.

    Science.gov (United States)

    Fischer, Shira H; Armstrong, Courtney K; Duffy, Erin L; Hussey, Peter S

    Improving medication adherence is a common and challenging issue. Taking medications as prescribed becomes particularly difficult for individuals with multiple chronic conditions. Poor adherence can lead to exacerbated health issues and prolonged disease severity. Medication Therapy Management is increasingly being used to help clinics improve medication adherence and reduce adverse events, but factors that enable implementation of such programs are not well identified. To describe the factors associated with implementation of an innovative pharmacy program and to measure the impact of the intervention. This mixed-methods cohort study in a federal qualified health center with its own pharmacy examined the implementation and the impact of a broad program including MTM. The intervention included appointments with pharmacists, communication between pharmacists and physicians, and, for some, monthly pre-packaged medications. Semi-structured interviews with patients and staff were recorded, transcribed, and analyzed for themes relating to implementation, satisfaction, and challenges. Quantitative methods using data collected by the pharmacists at each visit were used to compare the first visit to those at later visits and provided measures of impact on diabetes control, statin use, and medication-related problems (MRPs). Qualitative interviews identified enabling factors that contributed to successful implementation of this program, including: program factors such as data access, communication with patients, and dedicated staff; organizational factors such as culture of integration, leadership support, and staffing; and lastly, environmental factors such as the availability of 340B funding. Quantitative analyses were limited by poor retention and lack of a similarly-documented comparison group. Health outcomes were not found to be significantly better, though there was a significant decrease in some kinds of MRPs. This program was well received by patients and staff and

  9. Integrating Hydrology and Historical Geography in an Interdisciplinary Environmental Masters Program in Northern Ontario, Canada

    Science.gov (United States)

    Greer, Kirsten; James, April

    2016-04-01

    Research in hydrology and other sciences are increasingly calling for new collaborations that "…simultaneously explore the biogeophysical, social and economic forces that shape an increasingly human-dominated global hydrologic system…" (Vorosmarty et al. 2015, p.104). With many environmental programs designed to help students tackle environmental problems, these initiatives are not without fundamental challenges (for example, they are often developed around a single epistemology of positivism). Many environmental graduate programs provide narrow interdisciplinary training (within the sciences, or bridging to the social sciences) but do not necessarily engage with the humanities. Geography however, has a long tradition and history of bridging the geophysical, social sciences, and humanities. In this paper, we reflect on new programming in an Interdisciplinary Master's program in Northern Ontario, Canada, inspired by the rich tradition of geography. As Canada Research Chairs trained in different geographical traditions (historical geography and hydrology), we aim to bring together approaches in the humanities and geophysical sciences to understand hydrological and environmental change over time. We are teaching in a small, predominantly undergraduate University located in Northern Ontario, Canada, a region shaped significantly by colonial histories and resource development. The Masters of Environmental Studies/Masters of Environmental Sciences (MES/MESc) program was conceived from a decade of interdisciplinary dialogue across three undergraduate departments (Geography, Biology and Chemistry, History) to promote an understanding of both humanistic and scientific approaches to environmental issues. In the fall of 2015, as part of our 2015-2020 Canada Research Chair mandates, we introduced new initiatives to further address the integration of humanities and sciences to our graduate program. We believe the new generation of environmental scientists and practioners

  10. A data-driven algorithm integrating clinical and laboratory features for the diagnosis and prognosis of necrotizing enterocolitis.

    Directory of Open Access Journals (Sweden)

    Jun Ji

    Full Text Available Necrotizing enterocolitis (NEC is a major source of neonatal morbidity and mortality. Since there is no specific diagnostic test or risk of progression model available for NEC, the diagnosis and outcome prediction of NEC is made on clinical grounds. The objective in this study was to develop and validate new NEC scoring systems for automated staging and prognostic forecasting.A six-center consortium of university based pediatric teaching hospitals prospectively collected data on infants under suspicion of having NEC over a 7-year period. A database comprised of 520 infants was utilized to develop the NEC diagnostic and prognostic models by dividing the entire dataset into training and testing cohorts of demographically matched subjects. Developed on the training cohort and validated on the blind testing cohort, our multivariate analyses led to NEC scoring metrics integrating clinical data.Machine learning using clinical and laboratory results at the time of clinical presentation led to two nec models: (1 an automated diagnostic classification scheme; (2 a dynamic prognostic method for risk-stratifying patients into low, intermediate and high NEC scores to determine the risk for disease progression. We submit that dynamic risk stratification of infants with NEC will assist clinicians in determining the need for additional diagnostic testing and guide potential therapies in a dynamic manner.http://translationalmedicine.stanford.edu/cgi-bin/NEC/index.pl and smartphone application upon request.

  11. Dynamic Features of the Highly Excited Vibrational States of the HOCl Non-Integrable System Based on the Dynamic Potential and Lyapunov Exponent Approaches.

    Science.gov (United States)

    Wang, Aixing; Fang, Chao; Liu, Yibao

    2017-01-07

    In this article the dynamic features of the highly excited vibrational states of the hypochlorous acid (HOCl) non-integrable system are studied using the dynamic potential and Lyapunov exponent approaches. On the condition that the 3:1 resonance between the H-O stretching and H-O-Cl bending modes accompany the 2:1 Fermi resonance between the O-Cl stretching and H-O-Cl bending modes, it is found that the dynamic potentials of the highly excited vibrational states vary regularly with different Polyad numbers (P numbers). As the P number increases, the dynamic potentials of the H-O stretching mode remain the same, but those of the H-O-Cl bending mode gradually become complex. In order to investigate the chaotic and stable features of the highly excited vibrational states of the HOCl non-integrable system, the Lyapunov exponents of different energy levels lying in the dynamic potentials of the H-O-Cl bending mode (P = 4 and 5) are calculated. It is shown that the Lyapunov exponents of the energy levels staying in the junction of Morse potential and inverse Morse potential are relative large, which indicates the degrees of chaos for these energy levels is relatively high, but the stabilities of the corresponding states are good. These results could be interpreted as the intramolecular vibrational relaxation (IVR) acting strongly via the HOCl bending motion and causing energy transfers among different modes. Based on the previous studies, these conclusions seem to be generally valid to some extent for non-integrable triatomic molecules.

  12. Integration of spectral, thermal, and textural features of ASTER data using Random Forests classification for lithological mapping

    Science.gov (United States)

    Masoumi, Feizollah; Eslamkish, Taymour; Abkar, Ali Akbar; Honarmand, Mehdi; Harris, Jeff R.

    2017-05-01

    The ensemble classifier, Random Forests (RF), is assessed for mapping lithology using the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) imagery over an area in southern Iran. The study area in the northern part of Rabor in the Kerman's Cenozoic magmatic arc (KCMA) is well exposed and contains some copper mineralization occurrences. In this research, the following six groups of ASTER datasets were used for RF classification: nine spectral bands in the VNIR and SWIR, five thermal bands in TIR, all 14 bands (including VNIR, SWIR, and TIR), band ratios, texture features, and principal components (PCs). The results showed that band ratios and all ASTER bands were able to more efficiently discriminate rock units than PC and texture images. The overall classification accuracies achieved were 62.58%, 55.40%, 65.04%, 67.12%, 54.54%, and 53.99% for the nine VNIR/SWIR bands, five TIR bands, all ASTER bands, band ratios, textural, and PCs datasets, respectively. Four datasets including all ASTER bands, band ratios, textural, and PCs datasets (37 bands) were combined as one group and applied in second RF classification which led to increase overall accuracy (up to 81.52%). Based on the four classified maps, an uncertainty map was produced to identify areas of variable (uncertain) classification results, which revealed that approximately 21.43% of all pixels on the classified map were highly uncertain. The RF algorithm found that 12 of the predictors were more important in the classification process. These predictors were used in a third RF classification, which resulted in an overall classification accuracy of 77.21%. Thus, the third RF classification decreases the accuracy. Field observations were used to validate our classification results.

  13. Integration-free induced pluripotent stem cells model genetic and neural developmental features of down syndrome etiology.

    Science.gov (United States)

    Briggs, James A; Sun, Jane; Shepherd, Jill; Ovchinnikov, Dmitry A; Chung, Tung-Liang; Nayler, Sam P; Kao, Li-Pin; Morrow, Carl A; Thakar, Nilay Y; Soo, Set-Yen; Peura, Teija; Grimmond, Sean; Wolvetang, Ernst J

    2013-03-01

    Down syndrome (DS) is the most frequent cause of human congenital mental retardation. Cognitive deficits in DS result from perturbations of normal cellular processes both during development and in adult tissues, but the mechanisms underlying DS etiology remain poorly understood. To assess the ability of induced pluripotent stem cells (iPSCs) to model DS phenotypes, as a prototypical complex human disease, we generated bona fide DS and wild-type (WT) nonviral iPSCs by episomal reprogramming. DS iPSCs selectively overexpressed chromosome 21 genes, consistent with gene dosage, which was associated with deregulation of thousands of genes throughout the genome. DS and WT iPSCs were neurally converted at >95% efficiency and had remarkably similar lineage potency, differentiation kinetics, proliferation, and axon extension at early time points. However, at later time points DS cultures showed a twofold bias toward glial lineages. Moreover, DS neural cultures were up to two times more sensitive to oxidative stress-induced apoptosis, and this could be prevented by the antioxidant N-acetylcysteine. Our results reveal a striking complexity in the genetic alterations caused by trisomy 21 that are likely to underlie DS developmental phenotypes, and indicate a central role for defective early glial development in establishing developmental defects in DS brains. Furthermore, oxidative stress sensitivity is likely to contribute to the accelerated neurodegeneration seen in DS, and we provide proof of concept for screening corrective therapeutics using DS iPSCs and their derivatives. Nonviral DS iPSCs can therefore model features of complex human disease in vitro and provide a renewable and ethically unencumbered discovery platform. Copyright © 2012 AlphaMed Press.

  14. A hybrid feature selection algorithm integrating an extreme learning machine for landslide susceptibility modeling of Mt. Woomyeon, South Korea

    Science.gov (United States)

    Vasu, Nikhil N.; Lee, Seung-Rae

    2016-06-01

    An ever-increasing trend of extreme rainfall events in South Korea owing to climate change is causing shallow landslides and debris flows in mountains that cover 70% of the total land area of the nation. These catastrophic, gravity-driven processes cost the government several billion KRW (South Korean Won) in losses in addition to fatalities every year. The most common type of landslide observed is the shallow landslide, which occurs at 1-3 m depth, and may mobilize into more catastrophic flow-type landslides. Hence, to predict potential landslide areas, susceptibility maps are developed in a geographical information system (GIS) environment utilizing available morphological, hydrological, geotechnical, and geological data. Landslide susceptibility models were developed using 163 landslide points and an equal number of nonlandslide points in Mt. Woomyeon, Seoul, and 23 landslide conditioning factors. However, because not all of the factors contribute to the determination of the spatial probability for landslide initiation, and a simple filter or wrapper-based approach is not efficient in identifying all of the relevant features, a feedback-loop-based hybrid algorithm was implemented in conjunction with a learning scheme called an extreme learning machine, which is based on a single-layer, feed-forward network. Validation of the constructed susceptibility model was conducted using a testing set of landslide inventory data through a prediction rate curve. The model selected 13 relevant conditioning factors out of the initial 23; and the resulting susceptibility map shows a success rate of 85% and a prediction rate of 89.45%, indicating a good performance, in contrast to the low success and prediction rate of 69.19% and 56.19%, respectively, as obtained using a wrapper technique.

  15. Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological features.

    Directory of Open Access Journals (Sweden)

    Yasuyuki Shimada

    Full Text Available Keratocystic odontogenic tumor (KCOT arises as part of Gorlin syndrome (GS or as a sporadic lesion. Gene mutations and loss of heterozygosity (LOH of the hedgehog receptor PTCH1 plays an essential role in the pathogenesis of KCOT. However, some KCOT cases lack evidence for gene alteration of PTCH1, suggesting that other genes in the hedgehog pathway may be affected. PTCH2 and SUFU participate in the occurrence of GS-associated tumors, but their roles in KCOT development are unknown. To elucidate the roles of these genes, we enrolled 36 KCOT patients in a study to sequence their entire coding regions of PTCH1, PTCH2 and SUFU. LOH and immunohistochemical expression of these genes, as well as the downstream targets of hedgehog signaling, were examined using surgically-excised KCOT tissues. PTCH1 mutations, including four novel ones, were found in 9 hereditary KCOT patients, but not in sporadic KCOT patients. A pathogenic mutation of PTCH2 or SUFU was not found in any patients. LOH at PTCH1 and SUFU loci correlated with the presence of epithelial budding. KCOT harboring a germline mutation (Type 1 showed nuclear localization of GLI2 and frequent histological findings such as budding and epithelial islands, as well as the highest recurrence rate. KCOT with LOH but without a germline mutation (Type 2 less frequently showed these histological features, and the recurrence rate was lower. KCOT with neither germline mutation nor LOH (Type 3 consisted of two subgroups, Type 3A and 3B, which were characterized by nuclear and cytoplasmic GLI2 localization, respectively. Type 3B rarely exhibited budding and recurrence, behaving as the most amicable entity. The expression patterns of CCND1 and BCL2 tended to correlate with these subgroups. Our data indicates a significant role of PTCH1 and SUFU in the pathogenesis of KCOT, and the genotype-oriented subgroups constitute entities with different potential aggressiveness.

  16. Plagiarism, Cheating and Research Integrity: Case Studies from a Masters Program in Peru

    Science.gov (United States)

    Carnero, Andres M.; Mayta-Tristan, Percy; Konda, Kelika A.; Mezones-Holguin, Edward; Bernabe-Ortiz, Antonio; Alvarado, German F.; Canelo-Aybar, Carlos; Maguiña, Jorge L.; Segura, Eddy R.; Quispe, Antonio M.; Smith, Edward S.; Bayer, Angela M.; Lescano, Andres G.

    2017-01-01

    Plagiarism is a serious, yet widespread type of research misconduct, and is often neglected in developing countries. Despite its far-reaching implications, plagiarism is poorly acknowledged and discussed in the academic setting, and insufficient evidence exists in Latin America and developing countries to inform the development of preventive strategies. In this context, we present a longitudinal case study of seven instances of plagiarism and cheating arising in four consecutive classes (2011–2014) of an Epidemiology Masters program in Lima, Peru, and describes the implementation and outcomes of a multifaceted, “zero-tolerance” policy aimed at introducing research integrity. Two cases involved cheating in graded assignments, and five cases correspond to plagiarism in the thesis protocol. Cases revealed poor awareness of high tolerance to plagiarism, poor academic performance, and widespread writing deficiencies, compensated with patchwriting and copy-pasting. Depending on the events’ severity, penalties included course failure (6/7) and separation from the program (3/7). Students at fault did not engage in further plagiarism. Between 2011 and 2013, the Masters program sequentially introduced a preventive policy consisting of: (i) intensified research integrity and scientific writing education, (ii) a stepwise, cumulative writing process; (iii) honor codes; (iv) active search for plagiarism in all academic products; and (v) a “zero-tolerance” policy in response to documented cases. No cases were detected in 2014. In conclusion, plagiarism seems to be widespread in resource-limited settings and a greater response with educational and zero-tolerance components is needed to prevent it. PMID:27848191

  17. Integrated experimental test program on waterhammer pressure pulses and associated structural responses within a feedwater sparger

    Energy Technology Data Exchange (ETDEWEB)

    Nurkkala, P.; Hoikkanen, J. [Imatran Voima Oy, Vantaa (Finland)

    1997-12-31

    This paper describes the methods and systems as utilized in an integrated experimental thermohydraulic/mechanics analysis test program on waterhammer pressure pulses within a revised feedwater sparger of a Loviisa generation VVER-440-type reactor. This program was carried out in two stages: (1) measurements with a strictly limited set of operating parameters at Loviisa NPP, and (2) measurements with the full set of operating parameters on a test article simulating the revised feedwater sparger. The experiments at Loviisa NPS served as an invaluable source of information on the nature of waterhammer pressure pulses and structural responses. These tests thus helped to set the objectives and formulate the concept for series of tests on a test article to study the water hammer phenomena. The heavily instrumented full size test article of a steam generator feedwater sparger was placed within a pressure vessel simulating the steam generator. The feedwater sparger was subjected to the full range of operating parameters which were to result in waterhammer pressure pulse trains of various magnitudes and duration. Two different designs of revised feedwater sparger were investigated (i.e. `grounded` and `with goose neck`). The following objects were to be met within this program: (1) establish the thermohydraulic parameters that facilitate the occurrence of water hammer pressure pulses, (2) provide a database for further analysis of the pressure pulse phenomena, (3) establish location and severity of these water hammer pressure pulses, (4) establish the structural response due to these pressure pulses, (5) provide input data for structural integrity analysis. (orig.). 3 refs.

  18. EM-54 Technology Development In Situ Remediation Integrated Program. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    The Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of Environmental Restoration and Waste Management (EM) in November 1989. EM manages remediation of all DOE sites as well as wastes from current operations. The goal of the EM program is to minimize risks to human health, safety and the environment, and to bring all DOE sites into compliance with Federal, state, and local regulations by 2019. EM-50 is charged with developing new technologies that are safer, more effective and less expensive than current methods. The In Situ Remediation Integrated Program (the subject of this report) is part of EM-541, the Environmental Restoration Research and Development Division of EM-54. The In Situ Remediation Integrated Program (ISR IP) was instituted out of recognition that in situ remediation could fulfill three important criteria: Significant cost reduction of cleanup by eliminating or minimizing excavation, transportation, and disposal of wastes; reduced health impacts on workers and the public by minimizing exposure to wastes during excavation and processing; and remediation of inaccessible sites, including: deep subsurfaces; in, under, and around buildings. Buried waste, contaminated soils and groundwater, and containerized wastes are all candidates for in situ remediation. Contaminants include radioactive wastes, volatile and non-volatile organics, heavy metals, nitrates, and explosive materials. The ISR IP tends to facilitate development of in situ remediation technologies for hazardous, radioactive, and mixed wastes in soils, groundwater, and storage tanks. Near-term focus is on containment of the wastes, with treatment receiving greater effort in future years.

  19. [Integrity].

    Science.gov (United States)

    Gómez Rodríguez, Rafael Ángel

    2014-01-01

    To say that someone possesses integrity is to claim that that person is almost predictable about responses to specific situations, that he or she can prudentially judge and to act correctly. There is a closed interrelationship between integrity and autonomy, and the autonomy rests on the deeper moral claim of all humans to integrity of the person. Integrity has two senses of significance for medical ethic: one sense refers to the integrity of the person in the bodily, psychosocial and intellectual elements; and in the second sense, the integrity is the virtue. Another facet of integrity of the person is la integrity of values we cherish and espouse. The physician must be a person of integrity if the integrity of the patient is to be safeguarded. The autonomy has reduced the violations in the past, but the character and virtues of the physician are the ultimate safeguard of autonomy of patient. A field very important in medicine is the scientific research. It is the character of the investigator that determines the moral quality of research. The problem arises when legitimate self-interests are replaced by selfish, particularly when human subjects are involved. The final safeguard of moral quality of research is the character and conscience of the investigator. Teaching must be relevant in the scientific field, but the most effective way to teach virtue ethics is through the example of the a respected scientist.

  20. SYSTEM-VALUE PRINCIPLES OF MANAGEMENT OF INTEGRATED PROGRAMS OF THE MILK PRODUCTION DEVELOPMENT BASED ON MODELING

    Directory of Open Access Journals (Sweden)

    Анатолій Миколайович ТРИГУБА

    2016-03-01

    Full Text Available On the basis of analysis and implementation of state programs of milk-trade development, the need for the improvement of instruments to manage by these programs are grounded. The scientific and methodological principles of management by technologically integrated development programs of milk-trade development based on systematic and evaluative approach and simulation are proposed. A conceptual model of technologically integrated milk-trade management system includes a range of interconnected technical and technological, organizational and technical subsystems, in each of which the value is formed. System-value principles of configuration grounding of the technologically integrated milk-trade management system foresee next elements: reveal the cause-effect relation between its subsystems, content of input actions changes, options, and resources for the operation of production subsystems. The identified systemic properties of individual subsystems of technologically integrated milk-trade management system are in the base of evaluation of value indices of subsystems functioning.